Module Database

Information for module GENEG002

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This module will provide a background to cardiovascular disease (CVD) and other related complex diseases and outline how genetics contributes to the development of these common disorders. The study of both polygenic and monogenic forms of the diseases will be outlined and how genetics may assist in CVD risk prediction in the future and personalised drug treatment.
The content of the module is as follows:
- Global burden of cardiovascular disease (CVD) and its genetic epidemiology.
- Candidate gene approaches and genome wide association studies on CVD.
- Genetic testing for CVD and the gene-environment interaction in determining disease risk.
- The genetics of type 2 diabetes, MODY, hypertension, stroke and aortic abdominal aneurism, FH, cardiomyopathies and congenital heart disease.
- Statistical analysis and scanning for complex disease genotypes and phenotypes
- Using genetics to determine causality and the role of transcription factors in complex disease development
- Personalised Medicine and translating genetics of disease into clinical practice

Module aims:

To provide a background to cardiovascular disease (CVD) and other complex diseases
To outline how genetics contributes to the development of these common disorders.

Module objectives:

Intended learning outcomes
- To understand the principles of Cardiovascular Genetics and Epidemiology and the role in health and disease
-Students will develop a systematic understanding of knowledge and current problems/insights related to CVD disease and its research
Critical thinking skills will be developed in terms of evaluating methodologies and results
Students will develop independent learning skills, original problem solving abilities, and presentation skills