Skin zinc levels were found to be low in patients with acne, psoriasis and
other skin diseases, suggesting that many of these patients have a zinc
deficiency. Michaelsson G et al: Patients with dermatitis herpetiformis, acne,
psoriasis and Darier's disease have low epidermal zinc concentrations. Acta
Derm Venereol 70(4):304-8, 1990.

Zinc intake is of borderline sufficiency in the French population. Zinc
supplementation has been shown to be beneficial against several conditions,
including acne, reduced immunity and infertility. Favier A: Current aspects
about the role of zinc in nutrition. Rev Prat 15(2):146-51, 1993.

In a trial on 76 acne patients the efficacy of a vitamin B3 gel was found to
be comparable to the efficacy of an antibiotic gel (clindamycin). Shalita AR et
al: Topical nicotinamide compared with clindamycin gel in the treatment of
inflammatory acne vulgaris. Int J Dermatol 1995 34(6):434-7, 1995.