Isolation and Partial Characterization of the Major Histocompati-Bility Antigen in the Chicken

Abstract

In a number of mammalian species it is well documented that the immune responses to a variety of antigens are controlled by the major histocompatibility gene complex (1–4). Several laboratories have recently shown that in the chicken as in mammals, the major histocompatibility complex controls various immune responses (5–10). These observations have resulted in increasing efforts in the study of the structure and in the elucidation of the function of the major histocompatibility complex and its various gene products.