The 22-year-old, the man of the match as Wigan beat Manchester City 1-0 in the FA Cup final last weekend, was stretchered off in Tuesday's 4-1 defeat at Arsenal – the result that sealed their relegation to the Championship.

McManaman only made his full Premier League debut in March, but his swift rise was capped when he was named in Stuart Pearce's under-21 party for the June tournament in Israel. Now, however, he will have to withdraw from it.

"Callum McManaman picked up an injury on Tuesday," Wigan manager Roberto Martinez said. "It is ligament damage in his right ankle.

"We expected the worst, but he is going to be out for the best part of three months, probably ten to 12 weeks. But probably that puts him out of the Under-21s, which is a real shame because he deserves to be there.

"It is such a joy to see him playing his football. It is such a joy for everyone. For me, he has been one of the sparks of the season, not just at Wigan.

"He has shown us all how to enjoy the game, to be incisive. He has rolled the years back to see the old-fashioned winger, taking people on, so he has no reason to feel down at all."