Cefotaxime

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In 2000, a new strain of Escherichia coli, serotype O25:H4, which demonstrates both high virulence and antibiotic resistance, was isolated in Munich. In particular, it has CTX-M beta-lactamases, or beta-lactamases against cefotaxime, previously an effective drug against gram-negative infections. It is a major source of serious urinary tract infections. [2]