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The Coming of Age of Drug-Susceptibility Testing for Tuberculosis

27 Sep 2018 - 10:45

Prof Helen Cox (left); Prof Valerie Mizrahi (right)

CIDRI-Africa Contributing and Principal Investigators A/Prof. Helen Cox and Prof. Valerie Mizrahi's editorial on genomic approaches to Mtb drug susceptibility testing was published yesterday in the New England Journal of Medicine. Profs Cox and Mizrahi discussed the paper published by Allix-Béguec and colleagues in the same issue in which they showed a strong correlation between whole-genome sequencing-based genotypic predictions of Mtb drug susceptibility, and phenotypic susceptibility as determined by culture.

"Our goals should include the provision of universal drug-susceptibility testing as a key requirement for meeting the WHO End TB targets.", they concluded.