This antibody may replace item sc-166399 from Santa Cruz Biotechnology.

Description of Target:

RHOA regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. RHOA serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. It may be an activator of PLCE1. RHOA is activated by ARHGEF2, which promotes the exchange of GDP for GTP.