Application Information: HAI-2 antibody, Internal

Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.

Predicted Target Size

28 KDa (note)

Positive Controls

human fetal heart

Form Supplied

Liquid

Concentration

0.5-1
mg/ml

Purification

Affinity Purified

Specifications: HAI-2 antibody, Internal

Full Name

serine peptidase inhibitor, Kunitz type, 2

Background

This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]