Basic Informations of Complement C5

References

PMID:19307471|Circulation. 2009;119:1805-1813
..."Activation of the alternative pathway led to generation of the anaphylatoxins C3a and C5a, which recruited neutrophils to the aortic wall. Moreover, antagonism of both C3a and C5a activity was required to block AAA, which suggests that each can independently promote the aneurysmal phenotype."...