The algorithm can also be used to obtain an approximation of the Laplacian of Gaussian when the ratio of size 2 to size 1 is roughly equal to 1. The Laplacian of Gaussian is useful for detecting edges that appear at various image scales or degrees of image focus. The exact values of sizes of the two kernels that are used to approximate the Laplacian of Gaussian will determine the scale of the difference image, differences of Gaussians have also been used for blob detection in the scale-invariant feature transform. In fact, the DoG as the difference of two Multivariate normal distribution has always a total null sum and convolving it with a uniform signal generates no response.]