Mausam Kalita, PhD

My ambition is to develop novel optical and chemical tools to solve diagnostic and therapeutic problems by integrating organic and material chemistry, biochemistry and biology. My research in chemistry-nanoscience-glycobiology interface has produced several peer-reviewed publications and a patent involving a nanosensor which diagnoses life-threatening contaminant in pharmaceutical grade heparin, an anticoagulant used extensively during surgery. This probe will protect humans from severe immune response stimulated by this contaminant. I am currently developing several other biosensors, which can image biomarkers involved in pathophysiological conditions such as cancer, diabetes, arthritis and bacterial infection. At UCSF, my projects focus on the development of a) low nanomolar inhibitors of glycosyltransferase enzymes for glioblastoma therapy (PI- Joanna Phillips) and b) PET probes for selective imaging of active bacterial infection (PI- David Wilson). We are excited to introduce our first PET probe in humans for infection screening later in 2018.

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