Detects miRNAs from smRNA-seq data, with an emphasis on separately annotating and quantifying functionally-distinct isoforms of canonical miRNAs, termed isomiRs. miRquant provides detailed information on the quality of the sequencing data, genome mapping statistics, abundance of other types of small RNAs such as tDRs (tRNA-derived RNAs) and yDRs (Y-RNA derived small RNAs), prevalence of post-transcriptional modifications such as A-to-I edits and 3’ non-templated nucleotide additions, and correlation in miRNA profiles across multiple samples. miRquant will be useful for researchers interested not only in quantifying known microRNAs but also mining the rich well of additional information embedded in small RNA-sequencing data.

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Maintainer

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Praveen Sethupathy
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miRquant institution(s)

Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Lineberger Comprehensive Cancer Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

miRquant funding source(s)

This work was supported in part by a grant from NIH/NIDDK (R01DK105965), from the American Heart Association (Collaborative Science Award awarded), and from the American Diabetes Association Pathway Program (1-16-ACE-47).