Acetaminophen/dextromethorphan/guaifenesin/pseudoephedrine is used in the treatment of cough and nasal congestion; cold symptoms and belongs to the drug class upper respiratory combinations. FDA has not classified the drug for risk during pregnancy. Acetaminophen/dextromethorphan/guaifenesin/pseudoephedrine 325 mg / 15 mg / 200 mg / 30 mg is not a controlled substance under the Controlled Substances Act (CSA).