Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

hydrocodone-ibuprofen oral and procarbazine oral

hydrocodone-ibuprofen oral increases toxicity of procarbazine oral by unknown mechanism. MAOIs may increase central nervous system (CNS) depression and hypotension (low blood pressure). Do not take within 14 days of MAOI use.

Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

procarbazine oral and hydrocodone-ibuprofen oral

procarbazine oral increases toxicity of hydrocodone-ibuprofen oral by unknown mechanism. MAOIs may increase central nervous system (CNS) depression and hypotension (low blood pressure). Do not take within 14 days of MAOI use.

Significant

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.