Half the tubuli were hypoplastic or hyalinized, with a thickened lamina, immature Sertoli cells, and spermatogonia. The spouse were made up of mature Sertoli cells and germ cells at all phases of differentiation .9,11 There have been markedly fewer Leydig cells in the patient’s testis-cells sample than in an example from an age-matched control . The expression patterns of the androgen receptor and of both markers of germ-cell-maturation histone H1 and proacrosin were very similar in samples from the patient’s testis and the control testis.13 The amount of intratesticular testosterone in the patient’s biopsy sample was approximately one eighteenth that of a specimen from an age-matched control ; the control worth matches values in earlier reviews.59 ng per gram of tissue) than in the control sample .