The Chamber supports general election candidates who are aligned with what it describes as a pro-business agenda. While it occasionally backs Democrats who agree with its philosophy, the bulk of its support goes to Republicans. More recently, however, the Chamber has spent money opposing tea party Republicans, who disagree with its positions. In 2014 it spent $1 million opposing Republican candidates, and $1.4 million opposing Democratic candidates. The group is planning to spend about $100 million in the 2016 election cycle.

known donors:

Freedom Partner Chamber of Congress, which, according to Politico, has deep ties to the Koch brothers, donated $5.5 million from 2012 to 2014, Crossroads GPS, whose president Stephen Law was formerly general counsel to the Chamber, gave $5.25 million in 2014. The Kentucky Opportunity Coalition also gave $1 million in 2014.