VCF2Networks

Genotype networks are a representation of the set of genotypes associated with a single phenotype, and they allow one to estimate properties such as the robustness of the phenotype to mutations, and the ability of its associated genotypes to evolve new adaptations. So far, though, genotype networks analysis has rarely been applied to population genetics data. To help fill this gap, VCF2Networks is a tool to determine and study genotype network structure from single-nucleotide variant data.

Maintainer

Publication for VCF2Networks

VCF2Networks citation

library_books

Human Genome Variation and the Concept of Genotype Networks

2014

PLoS One

PMCID: 4049842

PMID: 24911413

DOI: 10.1371/journal.pone.0099424

[…] Genotype Networks are computed using a customized version of Networks, a software produced by our group . VCF2Networks allows to parse a Variant Call Format (vcf) file , generate a genotype network from it, and calculate network properties. The igraph library and its python bindings are used to represent […]