In many tumors, persistently-active signal transducer and activator of transcription 3 (STAT3) imparts several oncogenic features such as survival, proliferation, angiogenesis, and immune escape. Therefore, STAT3 targeting in cancer and cancer-exposed dendritic cells (DCs) is important for cancer...

In recent years, the application of self-associating block copolymer based drug delivery systems has attracted increasing attention as nano-sized carriers for the encapsulation and the controlled delivery of water insoluble drugs. Most of the drug formulations are based on the “trial and error”...

Neurotrophic factor peptide analogues are capable of promoting healing by neurogenesis, enhancing neuronal survival and attenuating glial activation. In vivo peptide delivery is difficult due to susceptibility to proteases, but they are considered ideal therapeutics due to specificity, potency,...