Mitt Romney's debate comment about "binders full of women" has sparked a plethora of comedic artwork as well as anti-Mormon comments online.

Mitt Romney’s remark about “binders full of women” in Tuesday night’s debate is taking on a life of its own today, even being seized upon by anti-Mormon bigots on Twitter who suggest his comment refers to having multiple wives.

The Republican nominee used the phrase in discussing his efforts to find qualified women to serve in his cabinet when he was governor of Massachusetts.

As he responded to a question about equal pay for women, Romney said, “We took a concerted effort to go out and find women who had backgrounds that could be qualified to become members of our cabinet. I went to a number of women’s groups and said, can you help us find folks? And they brought us whole binders full of women.”

Even President Obama himself jumped on the binders bandwagon today during a campaign stop in Iowa.

“I’ve gotta tell you, we don’t have to collect a bunch of binders to find qualified, talented, terrific young women ready to work and teach in these fields right now!” Obama said as a crowd of some 2,800 at Cornell College, outside Cedar Rapids, cheered.

Emma G. Keller of Britain’s Guardian tried to explain why Romney’s remark struck a nerve with some women, saying: “Why did the phrase resonate? Because it was tone deaf, condescending and out of touch with the actual economic issues that women are so bothered about. The phrase objectified and dehumanized women. It played right into the perception that so many women have feared about a Romney administration – that a president Romney would be sexist and set women back.”

Business Insider notes that on a Republican National Committee conference call this morning, the GOP used to the comment to indicate President Obama has an “empty binder” of a plan for a second term as president.

“Obama has a weakness when it comes to the question, ‘Will the next four years be any different?’ And they won’t be,” RNC Chair Reince Priebus said.

“It’s the president that has the empty binder,” New Hampshire Sen. Kelly Ayotte added.

Meanwhile, David S. Bernstein of the Boston Phoenix claims the scenario of events when Romney was governor was not quite according to what was said in the debate.

What actually happened was that in 2002 – prior to the election, not even knowing yet whether it would be a Republican or Democratic administration – a bipartisan group of women in Massachusetts formed MassGAP to address the problem of few women in senior leadership positions in state government. There were more than 40 organizations involved with the Massachusetts Women’s Political Caucus (also bipartisan) as the lead sponsor.

They did the research and put together the binder full of women qualified for all the different cabinet positions, agency heads, and authorities and commissions. They presented this binder to Governor Romney when he was elected.