In Charlas de Café: pensamientos, anécdotas y confidencias (1920, 1967), 32. (Café Chats: Thoughts, Anecdotes and Confidences). As translated in Peter McDonald (ed.) Oxford Dictionary of Medical Quotations (2004), 83. A more complete translation attempted by Webmaster using Google Translate is “When you are not born rich and mighty, thus, struggle for existence, the most shrewd and pious behavior is to calm and reduce the toxicity of our rivals and adversaries with the chloroform of politeness and flattery. Proceed as the bacteriologist who, unable to kill the microbe, opt for embolization (?), ie, by converting it healthy vaccine.”

In Preface, written at Dresden in August 1818, first German edition, Die Welt als Wille und Vorstellung, 4 Bücher nebst einem Anhange der die Kritik der Kentischen Philosophie (1819), xv-xvi. As translated by E.F.J. Payne in The World as Will and Representation (1958, 1969), Vol. 1, xvii. In the preface, Schopenhauer is joking that some readers of his book may find his work does not interest them.

Question: If you were to pour a pound of molten lead and a pound of molten iron, each at the temperature of its melting point, upon two blocks of ice, which would melt the most ice, and why?Answer: This question relates to diathermancy. Iron is said to be a diathermanous body (from dia, through, and thermo, I heat), meaning that it gets heated through and through, and accordingly contains a large quantity of real heat. Lead is said to be an athermanous body (from a, privative, and thermo, I heat), meaning that it gets heated secretly or in a latent manner. Hence the answer to this question depends on which will get the best of it, the real heat of the iron or the latent heat of the lead. Probably the iron will smite furthest into the ice, as molten iron is white and glowing, while melted lead is dull.

A research laboratory jealous of its reputation has to develop less formal, more intimate ways of forming a corporate judgment of the work its people do. The best laboratories in university departments are well known for their searching, mutual questioning.

An old writer says that there are four sorts of readers: “Sponges which attract all without distinguishing; Howre-glasses which receive and powre out as fast; Bagges which only retain the dregges of the spices and let the wine escape, and Sives which retaine the best onely.” A man wastes a great many years before he reaches the ‘sive’ stage.

Address for the Dedication of the New Building of the Boston Medical Library (12 Jan 1901). Printed as 'Books and Men', The Boston Medical and Surgical Journal (17 Jan 1901), 144, No. 3, 60. [Presumably “Howre-glasses” refers to Hour-glasses. -Webmaster]

At their best, at their most creative, science and engineering are attributes of liberty—noble expressions of man’s God-given right to investigate and explore the universe without fear of social or political or religious reprisals.

Committees are dangerous things that need most careful watching. I believe that a research committee can do one useful thing and one only. It can find the workers best fitted to attack a particular problem, bring them together, give them the facilities they need, and leave them to get on with the work. It can review progress from time to time, and make adjustments; but if it tries to do more, it will do harm.

Common sense is science exactly in so far as it fulfills the ideal of common sense; that is, sees facts as they are, or at any rate, without the distortion of prejudice, and reasons from them in accordance with the dictates of sound judgment. And science is simply common sense at its best, that is, rigidly accurate in observation, and merciless to fallacy in logic.

Engineering is the science of economy, of conserving the energy, kinetic and potential, provided and stored up by nature for the use of man. It is the business of engineering to utilize this energy to the best advantage, so that there may be the least possible waste. (1908)

Examination for Inquiry on Scutari (20 Feb 1855). In Great Britain Parliament, Report upon the State of the Hospitals of the British Army in Crimea and Scutari, House of Commons Papers (1855), Vol. 33 of Sess 1854-55, 343.

He who designs an unsafe structure or an inoperative machine is a bad Engineer; he who designs them so that they are safe and operative, but needlessly expensive, is a poor Engineer, and … he who does the best work at lowest cost sooner or later stands at the top of his profession.

I tell [medical students] that they are the luckiest persons on earth to be in medical school, and to forget all this worry about H.M.O.'s and keep your eye on helping the patient. It's the best time ever to be a doctor because you can heal and treat conditions that were untreatable even a couple of years ago.

If you advertise to tell lies, it will ruin you, but if you advertise to tell the public the truth, and particularly to give information, it will bring you success. I learned early that to tell a man how best to use tires, and to make him want them, was far better than trying to tell him that your tire is the best in the world. If you believe that yours is, let your customer find it out.

If you have an idea that you wish your audience to carry away, turn it upside down and inside out, rephrasing it from different angles. Remember that the form in which the thing may appear best to you may not impress half your audience.

Advice to the writer of his first paper for presentation at a scientific meeting. As expressed in quotation marks by Charles Thom in 'Robert Almer Harper', National Academy Biographical Memoirs (1948), 25, 233-234. Also, in Thom's words, “[Harper] added that a miscellaneous audience can not he expected to carry away a lot of separate facts but one good idea, well pictured out, will be remembered by some of them.”

In order that the relations between science and the age may be what they ought to be, the world at large must be made to feel that science is, in the fullest sense, a ministry of good to all, not the private possession and luxury of a few, that it is the best expression of human intelligence and not the abracadabra of a school, that it is a guiding light and not a dazzling fog.

In the discovery of lemmas the best aid is a mental aptitude for it. For we may see many who are quick at solutions and yet do not work by method ; thus Cratistus in our time was able to obtain the required result from first principles, and those the fewest possible, but it was his natural gift which helped him to the discovery.

As given in Euclid, The Thirteen Books of Euclid's Elements, translated from the text of Johan Ludvig Heiberg by Sir Thomas Little Heath, Vol. 1, Introduction and Books 1,2 (1908), 133. The passage also states that Proclus gives the definition of the term lemma as a proposition not proved beforehand. Glenn Raymond Morrow in A Commentary on the First Book of Euclid's Elements (1992), 165, states nothing more seems to be known of Cratistus.

It is always the case with the best work, that it is misrepresented, and disparaged at first, for it takes a curiously long time for new ideas to become current, and the older men who ought to be capable of taking them in freely, will not do so through prejudice.

From letter reprinted in Journal of Political Economy (Feb 1977), 85, No. 1, back cover, as cited in Stephen M. Stigler, The History of Statistics: The Measurement of Uncertainty Before 1900 (1986), 307. Stigler notes the letter is held by David E. Butler of Nuffield College, Oxford.

It is for such inquiries the modern naturalist collects his materials; it is for this that he still wants to add to the apparently boundless treasures of our national museums, and will never rest satisfied as long as the native country, the geographical distribution, and the amount of variation of any living thing remains imperfectly known. He looks upon every species of animal and plant now living as the individual letters which go to make up one of the volumes of our earth’s history; and, as a few lost letters may make a sentence unintelligible, so the extinction of the numerous forms of life which the progress of cultivation invariably entails will necessarily render obscure this invaluable record of the past. It is, therefore, an important object, which governments and scientific institutions should immediately take steps to secure, that in all tropical countries colonised by Europeans the most perfect collections possible in every branch of natural history should be made and deposited in national museums, where they may be available for study and interpretation. If this is not done, future ages will certainly look back upon us as a people so immersed in the pursuit of wealth as to be blind to higher considerations. They will charge us with having culpably allowed the destruction of some of those records of Creation which we had it in our power to preserve; and while professing to regard every living thing as the direct handiwork and best evidence of a Creator, yet, with a strange inconsistency, seeing many of them perish irrecoverably from the face of the earth, uncared for and unknown.

I’ve met a lot of people in important positions, and he [Wernher von Braun] was one that I never had any reluctance to give him whatever kind of credit they deserve. He owned his spot, he knew what he was doing, and he was very impressive when you met with him. He understood the problems. He could come back and straighten things out. He moved with sureness whenever he came up with a decision. Of all the people, as I think back on it now, all of the top management that I met at NASA, many of them are very, very good. But Wernher, relative to the position he had and what he had to do, I think was the best of the bunch.

Lay aside all conceit Learn to read the book of Nature for yourself. Those who have succeeded best have followed for years some slim thread which once in a while has broadened out and disclosed some treasure worth a life-long search.

Man tries to make for himself in the fashion that suits him best a simplified and intelligible picture of the world; he then tries to some extent to substitute this cosmos of his for the world of experience, and thus to overcome it. This is what the painter, the poet, the speculative philosopher, and the natural scientist do, each in his own fashion. Each makes this cosmos and its construction the pivot of his emotional life, in order to find in this way the peace and security which he cannot find in the narrow whirlpool of personal experience.

No politics, no committees, no reports, no referees, no interviews – just highly motivated people picked by a few men of good judgment.[Describing the compelling ideas of Max Perutz on how best to nurture research.]

Progress is achieved by exchanging our theories for new ones which go further than the old, until we find one based on a larger number of facts. … Theories are only hypotheses, verified by more or less numerous facts. Those verified by the most facts are the best, but even then they are never final, never to be absolutely believed.

Religion shows a pattern of heredity which I think is similar to genetic heredity. ... There are hundreds of different religious sects, and every religious person is loyal to just one of these. ... The overwhelming majority just happen to choose the one their parents belonged to. Not the sect that has the best evidence in its favour, the best miracles, the best moral code, the best cathedral, the best stained-glass, the best music when it comes to choosing from the smorgasbord of available religions, their potential virtues seem to count for nothing compared to the matter of heredity.

Scientists wrote beautifully through the 19th century and on into the early 20th. But somewhere after that, coincident with the explosive growth of research, the art of writing science suffered a grave setback, and the stultifying convention descended that the best scientific prose should sound like a non-human author addressing a mechanical reader.

Some of the scientists, I believe, haven’t they been changing their opinion a little bit on global warming? There’s a lot of differing opinions and before we react I think it’s best to have the full accounting, full understanding of what’s taking place.

Students who have attended my [medical] lectures may remember that I try not only to teach them what we know, but also to realise how little this is: in every direction we seem to travel but a very short way before we are brought to a stop; our eyes are opened to see that our path is beset with doubts, and that even our best-made knowledge comes but too soon to an end.

Success is achievable without public recognition, and the world has many unsung heroes. The teacher who inspires you to pursue your education to your ultimate ability is a success. The parents who taught you the noblest human principles are a success. The coach who shows you the importance of teamwork is a success. The spiritual leader who instills in you spiritual values and faith is a success. The relatives, friends, and neighbors with whom you develop a reciprocal relationship of respect and support - they, too, are successes. The most menial workers can properly consider themselves successful if they perform their best and if the product of their work is of service to humanity.

Take the rose—most people think it very beautiful: I don’t care for It at all. I prefer the cactus, for the simple reason that it has a more interesting personality. It has wonderfully adapted itself to its surroundings! It is the best illustration of the theory of evolution in plant life.

The American, by nature, is optimistic. He is experimental, an inventor and a builder who builds best when called upon to build greatly. Arouse his will to believe in himself, give him a great goal to believe in, and he will create the means to reach it.

Given with date 1 Jan 1960 in Brian M. Thomsen, The Dream That Will Not Die: Inspiring Words of John, Robert, and Edward Kennedy (2010), 79. Webmaster has not seen a primary document for this quote. Although it is widely circulated, the origin is usually never cited. If you know the primary source, please contact Webmaster.

The best and safest way of philosophising seems to be, first to enquire diligently into the properties of things, and to establish those properties by experiences [experiments] and then to proceed slowly to hypotheses for the explanation of them. For hypotheses should be employed only in explaining the properties of things, but not assumed in determining them; unless so far as they may furnish experiments.

In speech, 'Education for Creativity in the Sciences', Conference at New York University, Washington Square. As quoted by Gene Currivan in 'I.Q. Tests Called Harmful to Pupil', New York Times (16 Jun 1963), 66.

The Engineer is one who, in the world of physics and applied sciences, begets new things, or adapts old things to new and better uses; above all, one who, in that field, attains new results in the best way and at lowest cost.

The moral principle inherent in evolution, that nothing can be gained in this world without an effort; the ethical principle inherent in evolution is that only the best has the right to survive; the spiritual principle in evolution is the evidence of beauty, of order, and of design in the daily myriad of miracles to which we owe our existence.

The picture of scientific method drafted by modern philosophy is very different from traditional conceptions. Gone is the ideal of a universe whose course follows strict rules, a predetermined cosmos that unwinds itself like an unwinding clock. Gone is the ideal of the scientist who knows the absolute truth. The happenings of nature are like rolling dice rather than like revolving stars; they are controlled by probability laws, not by causality, and the scientist resembles a gambler more than a prophet. He can tell you only his best posits—he never knows beforehand whether they will come true. He is a better gambler, though, than the man at the green table, because his statistical methods are superior. And his goal is staked higher—the goal of foretelling the rolling dice of the cosmos. If he is asked why he follows his methods, with what title he makes his predictions, he cannot answer that he has an irrefutable knowledge of the future; he can only lay his best bets. But he can prove that they are best bets, that making them is the best he can do—and if a man does his best, what else can you ask of him?

The power that produced Man when the monkey was not up to the mark, can produce a higher creature than Man if Man does not come up to the mark. What it means is that if Man is to be saved, Man must save himself. There seems no compelling reason why he should be saved. He is by no means an ideal creature. At his present best many of his ways are so unpleasant that they are unmentionable in polite society, and so painful that he is compelled to pretend that pain is often a good. Nature holds no brief for the human experiment: it must stand or fall by its results. If Man will not serve, Nature will try another experiment.

The psychiatric interviewer is supposed to be doing three things: considering what the patient could mean by what he says; considering how he himself can best phrase what he wishes to communicate to the patient; and, at the same time, observing the general pattern of the events being communicated. In addition to that, to make notes which will be of more than evocative value, or come anywhere near being a verbatim record of what is said, in my opinion is beyond the capacity of most human beings.

The world has arisen in some way or another. How it originated is the great question, and Darwin's theory, like all other attempts, to explain the origin of life, is thus far merely conjectural. I believe he has not even made the best conjecture possible in the present state of our knowledge.

There was, I think, a feeling that the best science was that done in the simplest way. In experimental work, as in mathematics, there was “style” and a result obtained with simple equipment was more elegant than one obtained with complicated apparatus, just as a mathematical proof derived neatly was better than one involving laborious calculations. Rutherford's first disintegration experiment, and Chadwick's discovery of the neutron had a “style” that is different from that of experiments made with giant accelerators.

From 'Physics in a University Laboratory Before and After World War II', Proceedings of the Royal Society of London, Series A, (1975), 342, 463. As cited in Alan McComas, Galvani's Spark: The Story of the Nerve Impulse (2011), 107.

This is the patent-age of new inventionsFor killing bodies, and for saving souls,All propagated with the best intentions;Sir Humphrey Davy's lantern, by which coalsAre safely mined for in the mode he mentions,Tombuctoo travels, voyages to the Poles,Are ways to benefit mankind, as true,Perhaps, as shooting them at Waterloo.

This single Stick, which you now behold ingloriously lying in that neglected Corner, I once knew in a flourishing State in a Forest: It was full of Sap, full of Leaves, and full of Boughs: But now, in vain does the busy Art of Man pretend to vie with Nature, by tying that withered Bundle of Twigs to its sapless Trunk: It is at best but the Reverse of what it was; a Tree turned upside down, the Branches on the Earth, and the Root in the Air.

'A Meditation Upon a Broom-stick: According to The Style and Manner of the Honorable Robert Boyle's Meditations' (1703), collected in 'Thoughts On Various Subjects', The Works of Jonathan Swift (1746), Vol. 1, 55-56.

We are consuming our forests three times faster than they are being reproduced. Some of the richest timber lands of this continent have already been destroyed, and not replaced, and other vast areas are on the verge of destruction. Yet forests, unlike mines, can be so handled as to yield the best results of use, without exhaustion, just like grain fields.

We have not done the things that are necessary to lower emissions because these things fundamentally conflict with deregulated capitalism… We are stuck because the actions that would give us the best chance of averting catastrophe–and would benefit the vast majority–are extremely threatening to an elite minority that has a stranglehold over our economy, our political process, and most of our major media outlets.

We may fondly imagine that we are impartial seekers after truth, but with a few exceptions, to which I know that I do not belong, we are influenced—and sometimes strongly—by our personal bias; and we give our best thoughts to those ideas which we have to defend.

As quoted by Jessica Guynn, reporting on a media roundtable at a conference on Google’s campus, in 'Google’s Schmidt, Page and Brin hold court at Zeitgeist', Los Angeles Times (17 Sep 2008). On latimesblogs.latimes.com webpage.

When the world is mad, a mathematician may find in mathematics an incomparable anodyne. For mathematics is, of all the arts and sciences, the most austere and the most remote, and a mathematician should be of all men the one who can most easily take refuge where, as Bertrand Russell says, “one at least of our nobler impulses can best escape from the dreary exile of
the actual world.”

Which do I consider my greatest invention? … I like the phonograph best … because I love music. And then it has brought so much joy into millions of homes all over this country, and, indeed, all over the world.

Why do they [Americans] quarrel, why do they hate Negroes, Indians, even Germans, why do they not have science and poetry commensurate with themselves, why are there so many frauds and so much nonsense? I cannot soon give a solution to these questions ... It was clear that in the United States there was a development not of the best, but of the middle and worst sides of European civilization; the notorious general voting, the tendency to politics... all the same as in Europe. A new dawn is not to be seen on this side of the ocean.

The Oil Industry in the North American State of Pennsylvania and in the Caucasus (1877). Translated by H. M. Leicester, from the original in Russian, in 'Mendeleev's Visit to America', Journal of Chemical Education (1957), 34, 333.

[To give insight to statistical information] it occurred to me, that making an appeal to the eye when proportion and magnitude are concerned, is the best and readiest method of conveying a distinct idea.

In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion.
(1987) -- Carl Sagan