Notes:
This re-invention of Supergirl borrows heavily from several sources, much as Loeb's reinvention of Superman himself did. It will doubtless grow to have several distinctive eras. For the moment, though, it appears to be in what we might come to call the "Meet and Greet" era. Storylines in the first few issues follow on from Kara's decision in Superman/Batman to don the Kryptonian "S" and be "Supergirl". Stories through at least the end of 2005 seem to all be concerned with her meeting different, typically female, DCU heroes in search for answers about whom she should become.

Note: The Superman/Batman series (and especially issues #8-13) are integral to this run of Supergirl. Anyone attempting to start their exploration of Supergirl IV would be well-advised to read the Loeb-written issues of that series first, or at least the Trade Hardcover/Paperback, Superman/Batman: Supergirl. So closely do the two titles follow each other that Superman/Batman #19 is reprinted as Supergirl #0.