Qamar made her debut in the TV series Main Aurat Hoon. She won the PTV award for the best TV actress in both public and jury choice categories in the 16th Annual PTV awards on 23 July 2011 for her role in Tinkay.

In 2014, she starred in Main Manto directed by Sarmad Sultan Khoosat. She will next appear in the spin-off to Karachi Se Lahore called Lahore Se Aagey. It was announced that she will make her debut in Bollywood in Hindi Medium opposite Irrfan Khan.