Not sure if it would work on the larger ones but on the smaller ones you can entomb them in super glue gel. I had a couple on the base of my scoly and didn't want to risk the Aptasia X that close to...

In my opinion, for what it is worth, I would put the return pump in the middle with the refugium on the end. Put a bubble trap between the skimmer section and return pump but only one baffle between...