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Through seven successful editions, Sabiston & Spencer Surgery of the Chest has set the standard in cardiothoracic surgery references. Now, the new 8th Edition, edited by Frank W. Sellke, MD, Pedro J. del Nido, MD, and Scott J. Swanson, MD, carries on this tradition with updated coverage of today's essential clinical knowledge from leaders worldwide. Guidance divided into three major sections ; Adult Cardiac Surgery, Congenital Heart Surgery, and Thoracic Surgery, lets you quickly find what you need, while new and revised chapters reflect all of the important changes within this rapidly evolving specialty. Expert Consult functionality, new to this edition, enables you to access the complete contents of the 2-volume set from anyplace with an Internet connection for convenient consultation where and when you need it. This is an ideal source for mastering all of the most important current knowledge and techniques in cardiac and thoracic surgery, whether for specialty board review or day-to-day practice. Features short, focused chapters that help you find exactly what you need. Presents the work of international contributors who offer a global view of the entire specialty. Covers thoracic surgery as well as adult and pediatric cardiac surgery for a practical and powerful single source. Includes nearly 1,100 illustrations that help to clarify key concepts.

"This book is a warning. It aims to warn policy-makers, industry, academia civil society organisations, the media and the public about the threats and vulnerabilities facing our privacy, identity, trust, security and inclusion in the rapidly approaching world of ambient intelligence (AmI)." "In the near future, every manufactured product - our clothes, money, appliances, the paint on our walls, the carpets on our floors, our cars, everything - will be embedded with intelligence, networks of tiny sensors and actuators, which some have termed "smart dust". The AmI world is not far off. We already have surveillance systems, biometrics, personal communicators, machine learning and more. AmI will provide personalised services - and know more about us - on a scale dwarfing anything hitherto available." "In the AmI vision, ubiquitous computing, communications and interfaces converge and adapt to the user. AmI promises greater user-friendliness in an environment capable of recognising and responding to the presence of different individuals in a seamless, unobtrusive and often invisible way. While most stakeholders paint the promise of AmI in sunny colours, there is a dark side to AmI as well." "The book identifies threats and vulnerabilities and illustrates them by means of four "dark scenarios". The authors set out a structured methodology for analysing AmI scenarios and propose safeguards to counter the foreseen threats and vulnerabilities. They make recommendations to policy-makers and other stakeholders about what they can do to maximise the benefits from ambient intelligence and minimise the negative consequences."--Jacket.

Cosmetic products and their current regulatory framework -- Challenges related to cosmetic safety assessment in the EU -- Critical analysis of the safety assessment of cosmetic ingredients performed at the European level -- Safety assessment of cosmetic ingredients present in technical information files of finished products -- The cosmetic technical information file in practice -- The use of alternative methods in the safety assessment of cosmetic ingredients.

In medical practice, unfamiliarity with procedures increases the likelihood of occupational exposures. Learning to perform a procedure properly early on reinforces safe habits, improves overall surgical safety, and reduces occupational exposures. Safety in Office-Based Dermatologic Surgery is relevant to any healthcare professional who participates in office-based procedures, such as injections, biopsies, excisions, and laser surgery. The authors bring over 15 years? combined experience in training residents and medical students, enabling them to identify common unsafe practices in office-based surgery. Chapters are divided into individual procedures for easy referencing by students, trainees, as well as seasoned practitioners. Figures illustrate how seemingly innocuous actions and procedures can result in dangerous exposures to healthcare workers. Hazardous scenarios are subsequently followed with one or a series of safer solutions, with the accident and solution concisely explained and clearly illustrated.

"This book covers the regulatory required evaluation and study of the potentially adverse pharmacological effects of new drugs, from the general regulatory requirements to the specific studies that must be done and how they are performed and interpreted. Based on more than 30 years of direct experience, the author describes tricks and practical insights for making studies work and understanding why they don't. The second edition includes current regulations (US FDA and international especially Europe and Japan) and updated test methods, interpretation, and science"--Provided by publisher.

The SAGES Manual of Hernia Repair will serve as a state-of-the-art resource for hernia surgeons and residents alike who are interested in the rapidly evolving area of abdominal wall hernia repair. This manual captures and summarizes the current trends in the field, as well as describing the new ideas, programs, and strategies regarding hernia repair. Through a unique section called Current Debates in Inguinal Hernia Repair, this volume also provides readers an overview of the current opinions on many of the ongoing debates of this time period. Furthermore, the manual is lavishly illustrated, containing an array of instructional charts and photographs, and is authored by a panel of experts in hernia repair.Comprehensive and easily accessible, The SAGES Manual of Hernia Repair is a portable reference that will be of great value to all practicing surgeons and residents working in the field of abdominal wall hernia repair.

1. Introduction -- 2. Differences in the nature of chicken meat production and the implications for salmonella and campylobacter -- 3. Review of available scientific information on control of salmonella and campylobacter : occurrence and challenges, and state of the science -- 4. Examples of possible interventions for hazard reduction -- 5. Evaluation of likey outcomes of specific interventions -- 6. Development of a Web-based risk-management tool -- 7. Summarized considerations of CCFH request -- 8. References -- Appendix.

This second edition of Samii's Essentials in Neurosurgery contains revised and updated versions of chapters from the first edition plus contributions on new topics written by leading neurosurgeons who were trained by Professor Madjid Samii in Hannover, Germany. Almost all fields of neurosurgery are covered. The authors follow the traditional principles of Samii's philosophy in the diagnosis and management of various neurosurgical pathologies, while presenting their own personal experiences. The extensively illustrated texts document clearly how cutting-edge technology in neurosurgery is being applied in new approaches and techniques. This book will greatly assist neurosurgeons, ENT surgeons, neuroradiologists, neurologists, and neurophysiotherapists in their everyday practice.

Access the latest information available in the challenging area of HIV/AIDS management with Sande's HIV/AIDS Medicine, 2nd Edition. Authored by a veritable "who's who" of current global experts in the field, this medical reference book will provide you with all the practical, indispensable guidance you'll need to offer your patients the best possible care.Access reliable, up-to-the-minute guidance that addresses the realities of HIV/AIDS management in your geographical region, thanks to contributions from a global cast of renowned expert clinicians and researchers. Locate the clinically actionable information you need quickly with an organization that mirrors the current state of the AIDS epidemic and the different needs of Western vs. developing-world patients and clinicians. Diagnose AIDS manifestations confidently by comparing them to full-color clinical images. Improve patient outcomes with the latest findings on the management of AIDS as a chronic illness. Efficiently review essential data through numerous at-a-glance tables. Get the most relevant information available on pediatric HIV and AIDS issues; anti-retroviral drugs, including integrase inhibitors; and the use of second- and third-line anti-retroviral drugs in resource-poor settings. Stay current on the latest actionable information, such as using antiretroviral therapy in patients with tuberculosis and drug-resistant tuberculosis; antiretroviral therapy; immune reconstitution inflammatory syndromes (IRIS); and implementation of the HPV vaccine. The very latest in HIV/AIDS management from global experts with a concise approach and a clinical/practical focus.

"Includes comprehensive hazard information on the substances encountered in the workplace. The objective of the work is to promote safety by providing the most up-to-date hazard information available"--Provided by publisher. "Since its inception in the early 1950's, this book has become the "bible" for those who need to evaluate the hazard of substances used in commerce. The book contains extensive data on approximately 28,000 substances. It is designed to fill the information needs of professionals who must work with and evaluate the hazards of chemicals"--Provided by publisher.

Laparoendoscopic Single-Site Surgery (LESS) and Natural Orifice Transluminal Endoscopic Surgery (NOTES) are based on the premise that patients should benefit in terms of recovery time, physical discomfort, pain, and cosmesis if a surgical procedure can be performed without visible scarring. Scar-Less Surgery: NOTES, Transumbilical, and Others is a multi-disciplinary effort which weaves together the surgical aspects of these novel techniques. It is the first comprehensive reference on the subject providing state-of-the-art technical information to both general and urologic surgeons while also highlighting future developments and research needs.

For over 40 years this book has been an invaluable resource for the pathologist in practice and in training in helping to solve diagnostic problems at the microscope. Lavishly illustrated in full color throughout it covers all aspects of liver pathology from the normal, the hepatidities, childhood disease and neoplasms. Copious technical tips and diagnostic 'pearls' reflect the extensive experience and insight of the late Peter Scheuer and Jay Lefkowitch. Throughout the text histopathologic features are correlated with clinical features to provide a practical account of how pathology impacts the diagnosis and management of liver disease.

"Schizophrenia: Recent Advances in Diagnosis and Treatment is a major addition to the literature, offering practical, comprehensive coverage of diagnosis and treatment options, genetic issues, neuroimaging, long-term management of schizophrenia, and future directions and predictions of how clinical care of schizophrenia will change. The book is divided into five sections. Section 1 summarizes the present state of knowledge about the diagnosis and treatment of schizophrenia. This includes recent changes in the DSM 5 categorization of schizophrenia and its implications for treatment. Section 2 considers recent discoveries into its pathoetiology, including the status of biological markers, genetics and neuroimaging as they relate to diagnosis and potential novel therapeutic approaches. Section 3 explores the optimization of present therapeutic approaches; novel treatments; and management of the substantial risks associated with both the illness and its present therapies. Section 4 discusses progress in the long-term management of schizophrenia, focusing on biological and psychotherapeutic strategies to improve functioning and facilitate recovery. Section 5 considers future directions and predictions of how diagnosis and treatment of schizophrenia will change. An invaluable addition to the field, Schizophrenia: Recent Advances in Diagnosis and Treatment is a definitive resource that will be of great interest to all clinicians caring for patients with schizophrenia."--Publisher's website.

"The recent advances in many aspects of kidney diseases have mandated a new edition of Schrier's Diseases of the Kidney. As in previous editions, a group of international experts was assembled to present this information in a comprehensive, authoritative, concise, and readily accessible fashion. The chapters have been extensively revised and updated"--Provided by publisher.

The care of critically ill and injured children needs to be safe, evidence-based, equitable, efficient, timely, and family-centered. "Science and Practice of Pediatric Critical Care Medicine" discusses these changes in the specialty in greater scope and detail, offering the reader fresh insight into not only where we came from, but also where we are going as a specialty. Thus, this book is designed for all involved in the management of the pediatric critically ill patient, from physicians, residents and fellows in critical care, pulmonology, cardiology and pediatricians to specialist.

"Keeping his focus on America, Nathaniel Comfort introduces the community of scientists, physicians, and public health workers who have contributed to the development of medical genetics from the nineteenth century to today. He argues that medical genetics is closely related to eugenics, and indeed that the two cannot be fully understood separately. He also carefully examines how the desire to relieve suffering and to improve ourselves genetically, though noble, may be subverted. History makes clear that as patients and consumers we must take ownership of genetic medicine, using it intelligently, knowledgeably, and skeptically"-- Provided by publisher.

The book does not focus primarily on grammar, but includes sections on important facets, such as 'voices' and tenses. It also addresses problems associated with writing other texts (reports, reviews, emails, social/professional networking communications etc.). Composed (with inputs from numerous senior scientists) by authors who have written, revised or edited more than 4,000 papers, A Scientific Approach to Scientific Writing will be essential reading for non-native English-speaking students and researchers of all disciplines, and a valuable resource for those with English as a first language."--pub. desc.

"In the past three decades there has been a major sea change in the way healthcare is taught and carried out. Healthcare has been transformed from a "this is what you do" concept to a profession that has a significant educational and scientific basis with an ethos of evidence-based material. The healthcare professional is now more educated, very often to the degree and masters level. As a consequence, Practice and Procedures are continually changing with a corresponding improvement in healthcare. Concomitantly, the demand for comprehensive and focused evidenced-based text and scientific literature covering single areas of nursing and healthcare science or treatment has also increased. This then is the rational for the present series. The volume on Arthritis covers, rheumatoid arthritis, cytokines, leukocyte immunoglobulin-like receptors, alleles, cardiovascular risk, disease outcomes, treatment protocols, and drugs for arthritis. The series is designed for student nurses, practicing healthcare workers, qualified nurses and healthcare practitioners, post graduates, special project students, teachers, lecturers and professors of nursing and healthcare. It is also suitable for college, university or nursing school libraries as a reference guide"-- Provided by publisher.

"In the past three decades there has been a major sea change in the way healthcare is taught and carried out. Healthcare has been transformed from a "this is what you do" concept to a profession that has a significant educational and scientific basis with an ethos of evidence-based material. The healthcare professional is now more educated, very often to the degree and masters level. As a consequence, Practice and Procedures are continually changing with a corresponding improvement in healthcare. Concomitantly, the demand for comprehensive and focused evidenced-based text and scientific literature covering single areas of nursing and healthcare science or treatment has also increased. This then is the rational for the present series. This volume on Asthma covers, inter alia, asthma care in primary care centers, rhinosinusitis and asthma, asthma and psychological distress, inhalation techniques for different inhalers, emergency treatment for acute asthma, therapy for elderly patients, treatment for pediatric asthma, nursing care at home and so on. The series is designed for student nurses, practicing healthcare workers, qualified nurses and healthcare practitioners, post graduates, special project students, teachers, lecturers and professors of nursing and healthcare. It is also suitable for college, university or nursing school libraries as a reference guide"-- Provided by publisher.

Current epidemiological evidence suggests that at least one third of people with diabetes suffer from clinically relevant depressive disorders which often go unrecognized and untreated. Research also shows that people with depressive disorders have an increased risk of developing Type 2 diabetes. Furthermore, the prognosis is poorer for either disease when they are co-morbid than when they occur separately. Co-morbid depression and diabetes has a huge impact on quality of life and diabetes management, and is an important public health problem. While there are many screening instruments available to identify individuals who may have depression, selecting the most appropriate tool for use in a busy diabetes clinic or primary care setting may not be straightforward. Screening for Depression and Other Psychological Problems in Diabetes: A Practical Guide provides an up-to-date overview of available instruments for screening for depression in diabetes. The book reviews the most commonly used screening tools and considers their utility in a range of settings and countries. Guidance on the practical use of each tool is also provided. Other psychological problems found to be common in people with diabetes as well as diabetes-specific emotional difficulties are also considered. This book will appeal to a range of health care practitioners caring for people with diabetes, including diabetologists, general practitioners, practice nurses and diabetes specialist nurses. The issues considered here are applicable to all diabetes populations across the world and thus this book will appeal to a broad international readership as well as to researchers in the field of diabetes and mental health.

"Second harmonic generation serves as the basis for a microscope imaging contrast mechanism that visualizes cell and tissue structure and function. This book provides a complete overview of the principles underlying this technique and its current applications, including use in molecular sensing. Covering practical issues related to instrumentation, the text examines which kinds of external labels to use. It also gives detailed reviews of the use of second harmonic generation in biomedical research, from imaging of cancer and skin disorders to self-assembled gels, holographic SHG imaging, and tissue engineering applications"--Provided by publisher.

The commercialization of U.S. medicine -- The consequences of commercialized care -- The revolt of the payers -- "Consumer-driven" health care: the new new thing -- The reform we need -- Can we get there? do we want to? -- Lessons from Canada -- An open letter to my colleagues in the medical profession.

Open heart surgery has been in a continuous state of evolution since its earliest day. This book presents information on the management of secondary mitral valve regurgitation, one of most vexing problems to cardiologists, cardiac surgeons and patients. The treatment for primary mitral regurgitation is straightforward and has as its primary aim timely intervention to prevent left ventricular remodelling and left ventricular dysfunction. The management of secondary mitral regurgitation is more challenging as the mitral valve is not the primary cause of the disease. Furthermore, correcting mitral regurgitation without changing the left ventricular geometry is not guaranteed to be either beneficial or curative. Secondary Mitral Valve Regurgitation draws together contributions from a range of experienced cardiac surgeons, cardiologists, anesthetists and scientists to provide comprehensive and authoritative coverage on anatomy, hemodynamics, mechanism, echocardiographic assessment and treatment modalities. Many of the elusive details surrounding the best management of secondary mitral regurgitation are presented in a comprehensive manner so that this book will serve as an important primary source for readers wanting information on this important topic.

Neuroscientist Penny Lewis explores the latest research into the nighttime brain to understand the real benefits of sleep, showing how, while our body rests, the brain practices tasks it learned during the day, replays traumatic events to mollify them, and forges connections between distant concepts.

From the Publisher: Combining essential theory with "how-to" technical instruction, this concise guide is the leading reference for basic techniques in sedation and anxiety control in the dental office. The latest guidelines from the ADA and the American Society of Anesthesiologists keep you up-to-date with the latest medical standards. Content on patient management for pediatric, geriatric, physically compromised, and medically compromised patients helps you successfully treat any patient population. In-depth discussions of the pharmacology of commonly used sedative agents allow you to fully understand properties and characteristics of drugs used. Combines all aspects of sedation with essential theory and instruction. Boxes and tables highlight key information and make it easy to find important content. Chapter 40-Legal Considerations include the current liability standards for patient treatment to help you protect yourself and your patients. Chapter 41-The Controversial Development of Anesthesiology in Dentistry focuses on the growing controversies, legal and otherwise, from both without and within the profession. Updated patient management procedures provide the most current guidelines on everything from AHA CPR standards to the safest sedative procedures. Full-color art program shows anatomy and other important concepts in vibrant detail. Photos of the newest sedation and emergency equipment ensure you have the latest information on developments in the field.

This atlas demonstrates all components of the body through imaging, in much the same way that a geographical atlas demonstrates components of the world. Each body system and organ is imaged in every plane using all relevant modalities, allowing the reader to gain knowledge of density and signal intensity. Areas and methods not usually featured in imaging atlases are addressed, including the cranial nerve pathways, white matter tractography, and pediatric imaging. As the emphasis is very much on high-quality images with detailed labeling, there is no significant written component; however, 'pearl boxes' are scattered throughout the book to provide the reader with greater insight. This atlas will be an invaluable aid to students and clinicians with a radiological image in hand, as it will enable them to look up an exact replica and identify the anatomical components. The message to the reader is: Choose an organ, read the 'map,' and enjoy the journey.

"... Use[s] extensive research and interviews with leading physicians to show how subconscious stereotyping influences doctor-patient interactions, diagnosis, and treatment"--From publisher description.

With a strong patient-centered approach to care and an author team comprised of nurses and physicians, Seidel's Guide to Physical Examination, 8th Edition, addresses teaching and learning health assessment in nursing, medical, and a wide variety of other health-care programs, at both undergraduate and graduate levels. This new edition offers an increased focus on evidence-based practice and improved readability, along with integrated lifespan content and numerous special features such as Clinical Pearls and Physical Variations, Functional Assessment, and Staying Well boxes. Evidence-Based Practice in Physical Examination boxes supply you with current data on the most effective techniques for delivering quality patient care.Clinical Pearls lend insights and clinical expertise to help you develop clinical judgment skills.Functional Assessment boxes present a more holistic approach to patient care that extends beyond the physical exam to patients' functional ability.Staying Well boxes focus you on patient wellness and health promotion. Risk Factor boxes provide opportunities for patient teaching or genetic testing for a variety of conditions.Differential diagnosis content offers you an understanding of how disease presentations vary and specific information for how to make diagnoses from similar abnormal findings.Abnormal Findings tables equip you with a quick, illustrated reference that allows for comparisons of various abnormalities along with key symptoms and underlying pathophysiology.Sample Documentation boxes clarify appropriate professional language for the process of recording patient assessment data.

Selected References in Trauma and Orthopaedics provides a selection of references from the Trauma and Orthopedic literature, aimed at the surgeon preparing for the Intercollegiate Specialty Board examination, and similar end-of training examinations in other countries. It is the perfect guide for examiners and trainers who are preparing their trainees for the examination, as well as providing a literature basis for their own practice. Selected References in Trauma and Orthopaedics presents the classical papers underlying current practice as well as recent publications which have brought about innovation, clarified pathology or demonstrated outcomes. The references are presented with a brief summary which allows the reader to access a literature review, with the use of online resources, with the key references already identified.

"Edward Laws and Jason Sheehan have edited the first comprehensive guide to the management of the large varieties of pathologies that arise in the sellar and parasellar area. Over the past two decades change in management practices have been underpinned by a better understanding of the nature of the pathology, improved imaging and a refinement of both surgical and radiation therapy techniques. The location of the sellar and parasellar region has challenged neurosurgeons (and radiotherapists) to develop innovative refined approaches to the region, often using the best of skull base, endoscopic and microsurgical techniques. These have been utilized within the context of an improved understanding of the pathology, with the imperative that the treatment (or therapy) must optimize control of the pathology, whilst minimizing morbidity"--Provided by publisher.

"The semblance hypothesis explains how associative memory can result from the multidimensional semblance of activity from a specific set of presynaptic terminals at different orders of neurons. The hypothesized basic units are then examined for their feasibility to explain various physiological and pathological conditions of the nervous system, ranging from physiological time-scales of memory retrieval to plausible explanation for long term potentiation (LTP)"--Back cover.

Introduction -- Biogenic Amines in the Skin -- Melatoninergic System in the Skin -- Cutaneous Cholinergic System -- Corticotropin Signaling System in the Skin -- Steroidogenesis in the Skin -- Equivalent of Hypothalamo-Pituitary-Adrenal Axis in the Skin -- Cutaneous Secosteroidal System -- Equivalent of Hypothalamic-Pituitary-Thyroid Axis -- Cutaneous Opioid System -- Cutaneous Endocannabinoid System -- Perspectives.

"Sensory perception : mind and matter aims at a deeper understanding of the many facets of sensory perception and their relations to brain function and cognition. It is an attempt to promote the interdisciplinary discourse between the neurosciences and psychology, which speaks the language of cognitive experiences, and philosophy, which has been thinking about the meaning and origin of consciousness since its beginning. Leading experts contribute to such a discourse by informing the reader about exciting modern developments, both technical and conceptual, and by pointing to the big gaps still to be bridged. The various chapters provide access to scientific research on sensory perception and the mind from a broad perspective, covering a large spectrum of topics which range from the molecular mechanisms at work in sensory cells to the study of the unconscious and to neurophilosophy"--Publisher.

This book combines the instructive nature of a textbook with the visual aspects of an atlas to guide readers through the surgical principles, approaches, and techniques they need to dissect and clip cerebral aneurysms. Comprised of three concise sections, the book distills the distinguished author's vast experience into a series of easily accessible tutorials presented through clear, systematic descriptions and stunning, full-color illustrations. The first section explains the critical concepts and basic tenets of aneurysm microsurgery followed by a section on the various craniotomies and exposures necessary for successful clipping. The final section covers microsurgical anatomy, dissection strategies, and clipping techniques for each of the seven most common aneurysm types that are the focus of this book.

"The book is organized into three sections: tenets, the seven arteriovenous malformations, and selection. The tenets establish eight steps for AVM resection that comprise the phases of battle, as follows: step 1, exposure; step 2, subarachnoid dissection; step 3, defining the draining vein; step 4, defining the feeding arteries; step 5, pial dissection; step 6, parenchymal dissection;, step 7, ependymal or deep dissection; and step 8, finally resection. Critical concepts for dissection and resection are covered in the tenets section. In the section on the seven arteriovenous malformations, the anatomical battlefields for the lobes and deep regions are reviewed, 32 subtypes are described, and a resection strategy is presented for each subtype, step by step. The selection section addresses the secret to successful AVM surgery, which has nothing to do with surgical strategy or technique; rather, it is choosing your battles wisely"--Provided by publisher.

Children are no less spared from severe skin diseases. This textbook is designed as a practical clinical reference that will guide practitioners in treating difficult dermatoses in children in whom topical therapy has been unsuccessful. Individual sections are devoted to inflammatory diseases, immune-mediated/autoimmune diseases, tumors and proliferative disorders, and genodermatoses. Each chapter addresses which patients represent suitable candidates for systemic or other non-topical therapy and considerations and caveats in the use of such approaches. Potential treatments are then appraised from a current evidence-based perspective, with provision of detailed but relevant information and reference tables that summarize recommendations in use and monitoring. Future directions in management are also presented.

This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed.

Sexual dysfunction presents a major challenge to physicians who take on the task of treating men with prostate cancer. While curing the disease and saving a life is paramount, improving technologies and therapies offer skilled surgeons and clinical oncologists the opportunity to eradicate the disease without compromising sexual function. In Sexual Function of the Prostate Cancer Patient, John Mulhall and a panel of internationally recognized experts on prostate cancer and sexual function assess in detail the current state of prostate cancer treatment. The authors offer a broad overview of the pathophysiology and treatment of erectile dysfunction in men with prostate cancer, reviewing the latest findings regarding erection-sparing radiation therapy and sexual function outcomes after laparascopic and robotic prostatectomy. Additional chapters discuss intra-operative maneuvers to minimize post-operative erectile dysfunction and pharmacologic penile preservation and rehabilitation. Timely and authoritative, Sexual Function in the Prostate Cancer Patient is a highly readable guide to preserving post-prostate cancer sexual function that no urologist or radiation and medical oncologist should be without.

A short reader for a holistic approach on human sexuality and its disorders -- Interdisciplinary references in sexual medicine -- Basic understanding of human sexuality -- The spectrum of sexual disorders -- Principles of diagnostics in sexual medicine -- Principles of therapy in sexual medicine -- New challenges for sexual medicine.

"These guidelines for the treatment of persons who have sexually transmitted diseases (STDs) were developed by CDC after consultation with a group of professionals knowledgeable in the field of STDs who met in Atlanta, Georgia, during April 19-21, 2005. The information in this report updates the Sexually Transmitted Diseases Treatment Guidelines, 2002 (MMWR 2002;51[No. RR-6]). Included in these updated guidelines are an expanded diagnostic evaluation for cervicitis and trichomoniasis; new antimicrobial recommendations for trichomoniasis; additional data on the clinical efficacy of azithromycin for chlamydial infections in pregnancy; discussion of the role of Mycoplasma genitalium and trichomoniasis in urethritis/cervicitis and treatment-related implications; emergence of lymphogranuloma venereum protocolitis among men who have sex with men (MSM); expanded discussion of the criteria for spinal fluid examination to evaluate for neurosyphilis; the emergence of azithromycin- resistant Treponema pallidum; increasing prevalence of quinolone-resistant Neisseria gonorrhoeae in MSM; revised discussion concerning the sexual transmission of hepatitis C; postexposure prophylaxis after sexual assault; and an expanded discussion of STD prevention approaches." - p. 1

Sexually Transmitted Diseases: A Practical Guide for Primary Care, Second Edition, covers the diagnosis and treatment of STDs and other information critical to patient care, and reflects the last five years of significant changes in information about STDs. Updated to reflect the 2010 Centers for Disease Control Guidelines on the Treatment of STDs, this book also contains new information about: -the epidemiology of herpes virus infections -expedited partner therapy -changes in recommendations for HPV vaccination for men -changes in resistance patterns for antimicrobial therapy for gonorrhea and chlamydia -treatment recommendations for genital warts In order to better meet clinician needs, the book has been streamlined to quickly convey critical, evidence-based information. Whether seeking information about particular conditions (including HPV, herpes, syphilis, trichomaniasis, HIV, and others) or related patient issues (such as STD exposure evaluation and evaluation of sexual assault), Sexually Transmitted Diseases, Second Edition, contains all the knowledge clinicians need in a friendly, to-the-point format.

Comprehensive and complete, this book delivers the definitive, clinically oriented, cutting-edge guidance you need to achieve optimal outcomes managing the entire spectrum of gastrointestinal disorders. Make effective use of the latest endoscopic, robotic, and minimally invasive procedures as well as medical therapies with unbeatable advice from a "who's who" of international authorities! Shorten patient recovery time and lessen surgical risks using the latest minimally invasive and robotic techniques, including natural orifice translumenal endoscopic surgery, endoscopic plication for gastrointestinal reflux disease, and much more. Achieve total patient management by applying the newest pharmacologic treatments, including new drugs to be used alongside surgical therapies. Personalize treatments for IBD, cancer, and other inherited disorders with therapies based on genomics and proteomics. Take full advantage of the most recent advances in immunosuppression for transplant patients. Effectively treat diseases of the GI Tract with a comprehensive overview of both the basic science and the clinical information associated with surgery in this area.

Novalis® Shaped Beam Radiosurgery has set new standards by delivering highly precise radiation treatments to tumors anywhere in the body through the use of a proprietary multileaf collimator. By shaping the radiation beam to the exact contours of the tumor or lesion, Novalis permits maximum dose delivery to the entire tumor while protecting healthy tissue; this makes it eminently suitable for the treatment of irregularly shaped tumors. Novalis features 360° gantry rotation, stereoscopic kV X-ray imaging, and 6D robotic patient positioning. Dose delivery is typically achieved through fixed conformal beams, dynamic conformal arcs, and IMRT, and most brain treatments do not require an invasive head frame. This book provides a complete guide to radiosurgery treatments with Novalis. After a thorough discussion of the clinical and technical basis for Shaped Beam Radiosurgery, current clinical applications are considered in detail, including brain, body, skull base, and spinal tumors as well as arteriovenous malformations. Careful consideration is also given to future developments and applications, including new technologies that promise to offer even more accurate treatments. This state-of-the-art book will appeal to a wide audience of physicians and their multidisciplinary clinical and technical collaborators.

Pharmaceutical companies, academic researchers, and government agencies such as the Food and Drug Administration and the National Institutes of Health all possess large quantities of clinical research data. If these data were shared more widely within and across sectors, the resulting research advances derived from data pooling and analysis could improve public health, enhance patient safety, and spur drug development. Data sharing can also increase public trust in clinical trials and conclusions derived from them by lending transparency to the clinical research process. Much of this information, however, is never shared. Retention of clinical research data by investigators and within organizations may represent lost opportunities in biomedical research. Despite the potential benefits that could be accrued from pooling and analysis of shared data, barriers to data sharing faced by researchers in industry include concerns about data mining, erroneous secondary analyses of data, and unwarranted litigation, as well as a desire to protect confidential commercial information. Academic partners face significant cultural barriers to sharing data and participating in longer term collaborative efforts that stem from a desire to protect intellectual autonomy and a career advancement system built on priority of publication and citation requirements. Some barriers, like the need to protect patient privacy, present challenges for both sectors. Looking ahead, there are also a number of technical challenges to be faced in analyzing potentially large and heterogeneous datasets. This public workshop focused on strategies to facilitate sharing of clinical research data in order to advance scientific knowledge and public health. While the workshop focused on sharing of data from preplanned interventional studies of human subjects, models and projects involving sharing of other clinical data types were considered to the extent that they provided lessons learned and best practices. The workshop objectives were to examine the benefits of sharing of clinical research data from all sectors and among these sectors, including, for example: benefits to the research and development enterprise and benefits to the analysis of safety and efficacy. Sharing Clinical Research Data: Workshop Summary identifies barriers and challenges to sharing clinical research data, explores strategies to address these barriers and challenges, including identifying priority actions and "low-hanging fruit" opportunities, and discusses strategies for using these potentially large datasets to facilitate scientific and public health advances.

This comprehensive and stunningly illustrated textbook covers the entire spectrum of shoulder disease and arthroscopic techniques. It reviews the anatomy and the biomechanics of the shoulder, basic arthroscopic procedures, advanced reconstructive surgeries, and an overview on shoulder pathologies with a special focus on surgical approach. Shoulder Arthroscopy: Principles and Practice is a highly organized reference with all chapters following a standardized format: from detailed descriptions regarding epidemiology, pathophysiology, clinical findings, imaging, indication for treatment up to a step-by-step description of current surgical techniques, including tips and tricks on how to avoid the most common mistakes and complications. There is also an entire section dedicated to the evaluation of outcome measurements. The tips and techniques presented in this book are based on the Editor and his Contributors' individual experience. The book guides the orthopaedic resident and fellow who wants to focus on shoulder diseases, but it also represents a landmark reference for expert surgeons already involved in shoulder surgery.

The new edition of this step-by-step guide covers the entire spectrum of operative shoulder arthroscopy from initial operation room set-up through advanced reconstructive procedures. View all-new illustrations and apply the latest treatment options for Bankart repair, SLAP repair, and repair of a full range of rotator cuff lesions, along with strategies for stiff shoulders and osteoarthritis. The included DVD narrated by Dr. Gartsman demonstrates exactly how to complete both simple and complex operations in over three hours of video clips. Whether you are a novice or an experienced shoulder surgeon, improve your technique with the expertise of Dr. Gartsman. Provides detailed step-by-step descriptions of Dr. Gartsman's approach-including variations and complications-so that you can reproduce his results. Includes a DVD with video clips of procedures demonstrating Dr. Gartsman's surgical techniques. Presents the most current scientific data on the treatment outcomes of specific.

The ISAKOS Upper Extremity Committee (UEC) meets on a biannual basis for Closed Consensus Meetings. Each summit, a worldwide expert panel of surgeons and researchers convene for an in-depth discussion about a controversial topic. The purpose of this endeavor is to combine expertise and reach international consensus for the most appropriate management of various shoulder disorders. This booklet constitutes an integral part of the agreement encountered during these meetings. Section A provides a comprehensive review of the currently available Classifications and Outcome Scores for shoulder disorders, illustrating their potential pitfalls and limitations. Section B presents a summary of the Acromio-Clavicular Joint (ACJ) Consensus Summit, describing pioneering techniques to re-establish shoulder function after dislocation. Section C describes the current state of evidence of Rotator Cuff Disorders, providing novel theories regarding its underlying biomechanics and reconstruction techniques. The 2009-2013 ISAKOS UEC members hope the readers find this compendium an insightful update for daily shoulder management.

"Shoulder Instability, by Drs. Mark Provencher and Anthony Romeo, is the first comprehensive resource that helps you apply emerging research to effectively manage this condition using today's best surgical and non-surgical approaches. Detailed illustrations and surgical and rehabilitation videos clearly demonstrate key techniques like bone loss treatment, non-operative rehabilitation methods, multidirectional instability, and more. You'll also have access to the full contents online at www.expertconsult.com. "-- Publisher's website.

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