The Severe and Acute Respiratory Syndrome coronavirus (SARS CoV) is a newly-emerged virus that caused an outbreak of atypical pneumonia in the winter of 2002-2003. Polyclonal antibodies raised against the nucleocapsid (N) ...

Coronavirus N is a multifunctional protein that plays an essential role in enhancing the efficiency of virus transcription and assembly. This manuscript reports the analysis of HCoV-NL63 N protein by comparing the amino ...

The DEAD-box RNA helicase DDX5 is involved in many aspects of RNA
processing and has been implicated in a number of cellular processes involving
alteration of RNA secondary structure. The N-terminal region of DDX5, ...

A series of frameshift mutations within the 3a gene has been observed in culture-derived severe
acute respiratory syndrome coronavirus (SARS-CoV). We report here that viral RNA from clinical
samples obtained from SARS-CoV ...

Severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) caused a severe outbreak in several regions of the world in 2003. The
SARS-CoV genome is predicted to contain 14 functional open reading frames (ORFs). The ...

Severe acute respiratory syndrome (SARS), a life-threatening disease, is caused by the newly identified virus SARS coronavirus (SARSCoV).
In order to study the spike (S) protein of this highly contagious virus, we established ...

The severe acute respiratory syndrome coronavirus (SARS-CoV) genome contains open reading frames
(ORFs) that encode for several genes that are homologous to proteins found in all known coronaviruses. These
are the replicase ...

The genome of the severe acute respiratory syndrome coronavirus encodes for eight accessory viral proteins with no known homologues in other
coronaviruses. One of these is the 3b protein, which is encoded by the second ...

Besides genes that are homologous to proteins found in other coronaviruses, the severe acute respiratory
syndrome coronavirus genome also contains nine other potential open reading frames. Previously, we have
characterized ...

Severe acute respiratory syndrome coronavirus (SARS-CoV) 7a is an accessory protein with no known homologues. In this study, we
report the interaction of a SARS-CoV 7a and small glutamine-rich tetratricopeptide repeat-containing ...

RNA helicases of the DEAD (Asp-Glu-Ala-Asp)-box family of
proteins are involved in many aspects of RNA metabolism from
transcription to RNA decay, but most of them have also been
shown to be multifunctional. The DEAD-box ...