First large-scale use of chemicals such as chlorine and mustard gases.

1925

Geneva Protocol

Chemical warfare in WWI leads to the Geneva Protocol, which prohibits the use
of biological or chemical weapons in warfare, but does not ban the research or
production of these agents.

World War II

Despite the Geneva Protocol, chemical weapons use appears in WWII, although not
to the extent of WWI. Japan experiments with biological agents throughout the
30s and 40s and uses biological weapons in China and Manchuria.

1942

Gruinard Island

On Gruinard Island, off the coast of Scotland, the British conduct anthrax
tests on sheep. Today, the uninhabited island is still believed to be infected
with anthrax spores.

1950s and 60s

United States' Offensive Biological Program

The U.S. expands its offensive biological warfare program, which started during
World War II. Tests are conducted in secret by the U.S. Army in U.S. cities
using nonpathogenic bacteria.

In 1969, the program culminates with a large series of tests of its offensive
biological munitions in the Pacific Ocean. The tests, conducted by the U.S.
Army, involve a large number of ships loaded with caged animals. The tests are
considered a success.

At the end of 1969 President Nixon terminates the U.S. offensive biological warfare program and
orders all stockpiled weapons destroyed.

1972

Biological Weapons Convention

The Biological Weapons Convention (BWC), an international treaty that prohibits
the research, development and production of offensive biological weapons, is
established. The treaty does allow defensive work in the area of biological
weapons. The Soviet Union is one of the signatories.

April 1979

Sverdlovsk

An unusual anthrax outbreak occurs in the city of Sverdlovsk, USSR. Up to 100
are affected; at least 64 of them die.The Soviet government claims
contaminated meat is responsible.

Within a year debate begins within international scientific and intelligence
communities on whether the Sverdlovsk incident was a result of tainted meat or
an accidental release of anthrax spores from a nearby suspected biological
weapons facility. The debate will last for more than a decade.

1980

Eradication of Smallpox

After a long and successful vaccination campaign, smallpox is declared
eradicated worldwide. Only two labs will maintain smallpox stocks - the Center
for Disease Control in Atlanta and the Ivanovsky Institute in Moscow.

1980-88

Iraq

Chemical weapons are used extensively during the Iran-Iraq war, mainly by
Iraq.

After the Gulf War, in 1991, Iraq is ordered by the UN Security Council to stop
its biological, chemical and nuclear weapons program. The United Nations
Special Commission begins post-war inspections that have continued with
numerous interruptions and obstacles thrown up by Iraq.

1989

Pasechnick

Dr. Vladimir Pasechnick, the former director of the Leningrad Institute of
Ultrapure Biological Preparations, defects to the UK. He reveals that the
Soviet Union has an extensive offensive biological weapons program.

1989

Communism falls

Jan. 1991

Inspections

Joint U.S./UK inspection teams visit some biological facilities in Russia. The
Russians insist these are defensive facilities. The team believes they find
evidence of an offensive program that involves biological agents, such as
smallpox, anthrax, Marburg virus, and plague.

The following December, Russian inspection teams visit the closed-up U.S.
biological facilities and see that the U.S. has ended its offensive program.
However, the Russians report back to Moscow that the U.S. continues to have an
offensive program.

1992

Alibekov

Dr. Kanatjan Alibekov, former first deputy director of Biopreparat (the
civilian arm of the Soviet Union's biological warfare program) defects to the
United States. He confirms many of the West's suspicions of Russia's offensive
biological program, including the fact that Russia has used its smallpox stock
to make weapons.

Sverdlovsk Admission

President Yeltsin, without giving details, admits the Sverdlovsk anthrax
outbreak was caused by activity at the military facility. Around the same time,
a team of Western and Russian scientists visit the city of Sverdlovsk and
conclude the outbreak was caused by anthrax spores accidentally released from
the facility.

1993

Chemical Weapons Convention

The Chemical Weapons Convention (CWC) is established. It prohibits the
research and production of offensive chemical agents, similar to the BWC.

February 27, 1993

World Trade Towers Bombing

A bomb explodes at the World Trade Towers in New York City. Some analysts
suspect the bomb was laced with cyanide that failed to ignite. Six people are
killed and hundreds injured.

March 20, 1995

Tokyo Subway Attack

Members of the Aum Shinrikyo religious sect release sarin gas in the Tokyo
subway system, killing 12 and injuring over 5,000. Due to the poor quality of
the sarin agent and an ineffective dispersal system, casualties are lower than
expected. Afterwards, the religious group is found to have been experimenting
with anthrax and other biological agents.

April 25, 1997

B'nai B'rith

An envelope marked "antrachs" is discovered in the mailroom of the world
headquarters of B'nai B'rith in Washington DC. The fire department seals off
the building for what turns out to be a hoax.

March 1998

Anthrax Vaccination

The Defense Department begins an anthrax vaccination program to immunize all
military personnel against anthrax.

May 1998

Presidential Initiatives

President Clinton approves two new Presidential decision directives, known as
PDD-62 and PDD-63, to improve the country's ability to prevent and respond to
chemical and biological attacks.

President Clinton appoints Richard Clarke as the national coordinator for
antiterrorism programs. Over 40 government agencies have some responsibility
for dealing with terrorism. However, there currently is no centralized
group/organization for countering chemical or biological attacks.

An additional $1 billion is added to the defense budget for chemical and
biological defense.