Pilopine HS

SIDE EFFECTS

The following adverse experiences associated with pilocarpine therapy have
been reported: lacrimation, burning or discomfort, temporal or periorbital headache,
ciliary spasm, conjunctival vascular congestion, superficial keratitis and induced
myopia. Systemic reactions following topical administration are extremely rare,
but occasional patients are peculiarly sensitive to develop sweating and gastrointestinal
overactivity following suggested dosage and administration. Ocular reactions
usually occur during initiation of therapy and often will not persist with continued
therapy. Reduced visual acuity in poor illumination is frequently experienced
in older individuals and in those with lens opacity. A subtle corneal granularity
was observed in about 10% of patients treated with PILOPINE HS® (pilocarpine hydrochloride ophthalmic gel) . Cases of
retinal detachment have been reported during treatment with miotic agents; especially
in young myopic patients. Lens opacity may occur with prolonged use of pilocarpine.