WP CoffeeScript is a WordPress plugin that makes enqueueing CoffeeScript as easy as enqueueing JavaScript. Instead of using wp_enqueue_script(), as you would for JS, you just use enqueue_coffeescript(), which takes almost exactly the same arguments. The only difference is that the second argument should be the file path instead of the URL. If you'd like to compile multiple CS files into a single JS file, you can use an array of file paths as the second argument.