The party split during the debate on Confederation, with Howe and most other Liberals forming an Anti-Confederation Party, while supporters of confederation joined Tory Charles Tupper's Confederation Party. Howe, himself, initially opposed Confederation, but accepted it as a reality after initial attempts to scuttle it failed.

Prior to 1956, the Nova Scotia Liberal Party had ruled the province for 76 of its 89 years, most of that time with fewer than 5 opposition members. It had also ruled prior to confederation, and was responsible for bringing the first responsible government to North America. From 1882 to 1925, the Liberals held power for an unbroken 43 years, the second longest serving political dynasty in Canadian history, behind the Alberta PCs.[4]

From 1956 the Tories gained significant ground with Robert Stanfield's reformation of the "Progressive Conservatives", and have successfully challenged the Liberals for control of the government. The Liberals faltered in the province at the beginning of the 21st century, and for a time were the third-largest party in the House of Assembly, behind the Tories and the Nova Scotia New Democratic Party. After the Nova Scotia Liberal Party's dismal performance in the 2006 election (and failing to win his own seat), leader Francis MacKenzie announced his resignation.[5] He was succeeded by Stephen McNeil. In the 2009 election, the Liberals moved out of third-party status and formed the official opposition once again. In the 2013 election, the Liberals won a majority government, their first since the 1993 election under John Savage, and took office for the first time in 14 years.[6]