Wolfgang Petersen helms this 1995 techno-thriller loosely based on Richard Preston's nonfiction book The Hot Zone. Dustin Hoffman stars as Sam Daniels, a take-charge Army virologist trying to stave off a global biological meltdown when a rare lethal virus from the jungles of Zaire is brought into the country by an illegally smuggled monkey. Daniels's estranged wife (Rene Russo) discovers that the disease caused by the virus has a 100 percent mortality rate, so when the virus takes hold in a coastal California community, authorities plan to firebomb the town and everybody in it. Kevin Spacey won a New York Film Critics Circle Award in a supporting role.