On a night dominated by homers at the Stadium, Giancarlo Stanton hammered his 300th career home run Thursday in the third inning of the Yankees 8-7 loss to the Tigers.

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Stanton’s was one of eight home runs Thursday night. The Yankees, who are on pace to set a home run club record this season, hit three, while Detroit, who is dead last in the MLB in dingers, crushed five.

Dellin Betances gave up two of those homers in the top of the ninth for three runs to blow the save. He allowed a two-run shot to Victor Martinez and a solo home run to Niko Goodrum.

Happ, meanwhile, could not get out of the fifth, allowing five earned runs on a season-high tying 10 hits. He struck out three and went just 4.1 innings, marking by far his worst start since coming over to the Yankees from the Blue Jays last month.

Snapping a 40-at bat streak without a home run, Stanton crushed an 87-mile an hour changeup from Tigers’ lefty Francisco Liriano for the milestone. The two-run laser went into the right-field stands, 387 feet.

“I was just waiting for it to get over first, then I can enjoy it, That’s 300 right there,” Stanton said. “It was cool. Special moment for me. Put us up for the moment in the game too. It was cool.”

He received a standing ovation and came back out on the field from the dugout to tip his cap to the crowd at the Stadium. After the game, he got the game ball from fans that caught it in exchange for a bat and signed baseballs.

The outfielder hit the historic homer in his 1,119th game, becoming the fifth fastest player in baseball history to reach 300.