"'What are you going to do as a graduate student?' He just assumed that I was going to be one. He started talking about the electron microscope. I had never heard of such an animal, so it intrigued me. I guess within hours I decided to look at the electron microscopes as a career. "

"Roger, at Cornell University they have an incredible piece of scientific equipment known as the Tunneling Electron Microscope. Now, this microscope is so powerful that by firing electrons you can actually see images of the atom, the infinitesimally minute building blocks of our universe. Roger, if I were using that microscope right now, I still wouldn't be able to locate my interest in your problem. "

Frasier

"Once you add a computer between the microscope and the human observer, the whole game changes. At that point a microscope is no longer a device that has to generate a directly interpretable image. Now it's a device to record information."