Does anyone just do interface>computer?

Does anyone here bypass a mixer when recording into your software application? Or is a mixer and buses necessary for most?
I'd like to monitor to the talent with effects but would like to record just the basic tracks dry. Is this possible to do with most software?

Yes, I will be micing drums, amps, vocals, etc. to go into an analog to digital interface. I'm wondering if Cubase or other software applications allow to monitor back with effects. And If I want to use my analog rackmount reverbs and delays will I need a mixer?

Before I had outboard mic pres I just used the mic pres on the Digi 001. Now I use outboard pres, no mixer in the studio. If I'm out of preamp channels for MIDI gear I can run direct to line inputs on the 001.

I used a mixer just last month on a remote project I tracked with the MBox, mixed down to two tracks on the spot. That's about it.

I am routing from a stereo mike preamp into Audition running on a PC with Firewire and USB ports. The MAudio unit includes preamps, which I would want to bypass in favor of my (better) outboard preamp, so I am just using the A/D converter, basically.

Pretty similar here. I have a couple of signal chains that I can use. For vocals, I use a Focusrite Platinum TrakMaster channel strip directly into my M-Audio Delta 1010. For instruments, I usually go into a bank of BlueTube preamps then into Behringer compressors, then into the Delta. It's been working very well for me for a while now.