Phenobarbital (PB) is the prototype for a class of agents that produce marked induction in the genetic expression of a variety of metabolic enzymes in many species. One of the consequences of this induction is a change in ...

Background: Climate, land cover, and other environmental factors have been shown to have a direct impact on the epidemiology of vector-borne diseases. Warming temperatures combined with other effects of climate change and ...

Background: Climate change is projected to have serious long-term consequences for public health. The existing body of literature has largely characterized increases in hospitalization and mortality in relation to extreme ...

Assessing physical exposures in occupational health studies proves challenging regardless of the industry. In transportation, however, the problem is exacerbated by the fact that subjects are literally on the move. To ...

Pathogen transmission is a major concern when implementing sanitation systems in resource poor areas. Multiple studies have shown that ecological sanitation systems are an effective means for improving health in areas where ...

Current models of reproductive toxicity can be expensive, time consuming and require a large number of animals. While new in vitro methods have the potential to aid in reducing these burdens, the use of alternative models ...

Inhalation of particulate matter (PM) has long been implicated to influence health. Historically, emphasis has been placed on adverse effects to the lung, but advances in ambient PM monitoring and use of modern epidemiological ...

Exposure biomonitoring of organophosphate (OP) pesticides is a common practice to protect the health of agricultural workers. However, few studies have examined the association between markers of exposure and cholinesterase ...

<bold>Investigating Seasonal and Occupational Trends of Five Organophosphate Pesticides in House Dust in the Lower Yakima Valley, WA</bold> Katie M McDonald Organophosphate pesticides (OPs) are a class of insecticides and ...

The marine environment is the largest, most diverse and influential ecosystem on Earth. Still largely unexplored, the foundation for further ocean exploration begins with the most abundant and productive life forms in the ...

Workers chronically exposed to manganese (Mn) are at increased risk for the development of a Parkinsonism syndrome called manganism. A longitudinal cohort study worked with students at a welding training school to investigate ...

Despite evidence of adverse health effects resulting from exposure to welding fume and in particular to manganese (Mn), biomarkers of exposure are poorly understood and have not been thoroughly evaluated in a longitudinal ...

Exposure to diesel exhaust (DE) is prevalent in both occupational and environmental settings and has been associated with several adverse health outcomes including cancer and respiratory and cardiovascular disease. The ...

Pacific salmon populations on the west coast of the U.S. are increasingly threatened by anthropogenic activities. One potential factor driving the population declines is disruption of olfactory function via waterborne ...

Background The shellfish industry in Western Washington is an integral part of the State economy; with products being distributed in both domestic and international markets. Oysters and geoducks are two widely harvested ...

Fire is an essential ecological process. However, forest fire burn area in the Pacific Northwest is likely to double or even triple by the end of the 2040s based on projected climate change models and ecosystem evaluations. ...

It is increasingly becoming clear that astrocytes release numerous factors that contribute to the process of synaptogenesis. The fact that astrocytes express a wide range of neurotransmitter receptors suggest that they ...

Abstract Background: Molecular viability testing (MVT) is a novel RT-qPCR based diagnostic assay designed for rapid, sensitive, and specific detection of viable bacterial pathogens. Previous research has found it to be 5- ...

Background: In 2007, the International Agency for Research on Cancer classified shift work that involves circadian disruption as a probable human carcinogen. Nighttime chronodisruption has been shown to decrease concentrations ...