Textmining

Fusion

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

IL2506

Hypothetical protein (377 aa)

Predicted Functional Partners:

IL2508

Hypothetical protein (78 aa)

0.859

IL2507

Hypothetical protein (79 aa)

0.859

IL2509

rRNA (guanine-N1-)-methyltransferase (278 aa)

0.577

IL2510

Serine endoprotease (721 aa)

0.529

IL1186

NAD synthetase (543 aa)

0.487

aat

Leu/Phe-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (236 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

IL1186

IL2506

IL1186

IL2506

NAD synthetase

Hypothetical protein

0.487

IL1564

IL2506

IL1564

IL2506

S-adenosylmethionine-dependent methyltransferase

Hypothetical protein

0.440

IL2506

IL1186

IL2506

IL1186

Hypothetical protein

NAD synthetase

0.487

IL2506

IL1564

IL2506

IL1564

Hypothetical protein

S-adenosylmethionine-dependent methyltransferase

0.440

IL2506

IL2507

IL2506

IL2507

Hypothetical protein

Hypothetical protein

0.859

IL2506

IL2508

IL2506

IL2508

Hypothetical protein

Hypothetical protein

0.859

IL2506

IL2509

IL2506

IL2509

Hypothetical protein

rRNA (guanine-N1-)-methyltransferase

0.577

IL2506

IL2510

IL2506

IL2510

Hypothetical protein

Serine endoprotease

0.529

IL2506

aat

IL2506

IL0671

Hypothetical protein

Leu/Phe-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine

0.472

IL2507

IL2506

IL2507

IL2506

Hypothetical protein

Hypothetical protein

0.859

IL2507

IL2508

IL2507

IL2508

Hypothetical protein

Hypothetical protein

0.973

IL2507

IL2509

IL2507

IL2509

Hypothetical protein

rRNA (guanine-N1-)-methyltransferase

0.575

IL2508

IL2506

IL2508

IL2506

Hypothetical protein

Hypothetical protein

0.859

IL2508

IL2507

IL2508

IL2507

Hypothetical protein

Hypothetical protein

0.973

IL2508

IL2509

IL2508

IL2509

Hypothetical protein

rRNA (guanine-N1-)-methyltransferase

0.575

IL2509

IL2506

IL2509

IL2506

rRNA (guanine-N1-)-methyltransferase

Hypothetical protein

0.577

IL2509

IL2507

IL2509

IL2507

rRNA (guanine-N1-)-methyltransferase

Hypothetical protein

0.575

IL2509

IL2508

IL2509

IL2508

rRNA (guanine-N1-)-methyltransferase

Hypothetical protein

0.575

IL2509

IL2510

IL2509

IL2510

rRNA (guanine-N1-)-methyltransferase

Serine endoprotease

0.549

IL2510

IL2506

IL2510

IL2506

Serine endoprotease

Hypothetical protein

0.529

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Network Stats

Network Stats analysis is still ongoing, please wait ...

Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: