2,5-Dimethoxy-4-chloroamphetamin (DOC) is a psychedelic drug of the substituted phenethylamine and amphetamine chemical classes. There is no trace of DOC chemical prior to its first human usage in 1991 publication. The book “PhiKAL” (Phenethylamines i Have Known And Loved) by chemist Alexander Shulgin has mentioned that DOC powder was first synthesis and pharmacology in 1991. DOC is a highly dose sensitive psychedelic that is available as research chemical at online research chemical vendors.

DOC Chemical Formula C11H16ClNO2

DOC Molar mass 229.70 g/mol

DOC Structure

DOC Chemistry and Pharmacology

DOC is a substituted alpha-methylated phenethylamine. DOC has a stereocenter and its (R)-(−)-DOC is the more active stereoisomer. DOC acts as a selective 5-HT2A, 5-HT2B, and 5-HT2C receptor partial agonist. DOC is speculated to accelerate thought process, enhance immersion, conceptual thinking, thought connectivity, & much more.

DOB Chemical: Introduction

Dimethoxybromoamphetamine (DOB), also known as brolamfetamine and bromo-DMA, is a psychedelic compound that belongs to the phenethylamine class. DOB was first synthesized by Alexander Shulgin in 1967. Its synthesis and effects have been documented in Shulgin’s book “PiHKAL: A Chemical Love Story.”

Pharmacology

DOB is a 5-HT2A, 5-HT2B, and 5-HT2C receptor partial agonist. The psychedelic effects of DOB are mediated by its agonistic properties at the 5-HT2A receptor. Due to its selectivity characteristic, DOB is used in scientific research for studying the behaviour of 5-HT2 receptor subfamily. It is an agonist of human is trace amine-associated receptor 1 (TAAR1). It has been suggested by the scientific community that DOB is a prodrug metabolized in the lungs.

DOB Chemical formula C11H16BrNO2

DOB Molar mass 274.15 g/mol

DOB Structure

Reports have indicated that both DOC and DOB have similar chemical and pharmacological properties. So, possibilities are there that DOC can also be produced as prodrug in the lungs and it may also act as agonist to TRAA1 receptor. Further studies need to be conducted on the potential use of DOB and DOC for treating any lung disease as DOB is synthesized as prodrug in the lungs. So, if you’re thinking where can I buy research chemicals for your research purpose, then don’t worry. Just search on the Internet about reliable online research chemical suppliers in your area, order your product at the site of the most trusted company and you can get the highest quality DOB and DOC powders for your laboratory experiments delivered to your address.

Flubromazepam is a long-lasting psychoactive drug of the benzodiazepine class. It was first synthesized in 1960, but marketed in late 2012. It produces similar effects to other benzodiazepines chemicals such as anxiolytic, sedative, muscle relaxant, depressant and amnesic effects.

Flubromazepam is named for the fluorine and bromine substitutions on its core benzodiazepine skeleton. Flubromazepam belongs to the benzodiazepine class as it contains a 1,4 diazepine ring fused to a substituted benzene ring.

Pharmacology and Effects

Like other benzodiazepines, flubromazepam produces similar effects by binding to the benzodiazepine receptor site and magnifying the efficiency of the neurotransmitter gamma aminobutyric acid (GABA). Modulation of GABA receptor results in the sedating effects of flubromazepam on the nervous system. This research chemical has also been found to have anticonvulsant properties as it has the potential to bind to voltage-dependent sodium channels.

It has potential use for the short-term treatment of anxiety, insomnia, acute seizures, and the sedation of patients. Benzos are usually prescribed for legitimate medical reasons such as alcohol withdrawal and pain killer because of its sedative effects. It has been found that the drug has a strong anxiolytic as well as mood-lifting effect. However, it is currently exclusively sold by online research chemical vendors for use in clinical studies.

Research Uses and Scientific Experiment

Flubromazepam reportedly has a high addiction potential and risk of overdose. Flubromazepam is available in pellets, and is sold for in vitro research purposes only. Flubromazepam is not suitable for human consumption. With a longer half-life than other benzodiazeopines such as diazepam or etizolam, flubromazepam pellets present a fantastic opportunity to design innovative experiments aimed at understanding these chemical compounds and their in-vitro behaviour. This benzo chemical is suitable for use as a starting material in calibrators and controls for numerous GC/MS or LC/MS applications in forensic analysis, clinical toxicology and urine drug testing. If your interests lie in the pharmacology of etizolam, then Flubromazepam is an ideal substitute for comparable research. These types of chemicals are easily available in online stores. This benzodiazepine derivative has captured the imagination of scientists around the world. So, researchers who want to study all the fascinating properties of flubromazepam can buy research chemicals and legal highs of highest quality and purity online for research purposes from only trusted and reliable suppliers.

ETH-LAD was first synthesized by a Japanese research group in the 1970s. It has been described by pharmacologist Alexander Shulgin in his book “TiHKAL.” As an analogue of lysergic acid diethylamide (LSD), it has psychedelic properties but is more potent than LSD itself.

Chemistry of ETH-LAD

ETH-LAD is a structural analogue of lysergic acid having an N,N-diethylamide functional group bound to RN of the chemical structure. An indole derivative is present at the core polycyclic structure and tryptamine and phenethylamine groups embedded within it. ETH-LAD’s structure also has a bicyclic quinoline group that contains a bicyclic hexahydroindole.

Chemical Formula: C21H27N3O

Molar Mass: 337.47g/mol

Chemical Name: 6-ethyl-6-nor-lysergic acid diethylamide

ETH-LAD Effects

ETH-LAD acts as a 5-HT2A partial agonist. The psychedelic effects are believed to come from ETH-LAD’s efficacy at the 5-HT2Areceptors. 5-HT2A are widely distributed in the central nervous system, especially in brain region essential for learning and cognition. Antidepressants generally work by targeting these receptors. So, it is possible that this LSD analogue can be used as an antidepressant to treat depressed patients. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive and need to be found by the scientific community.

Legality

The UK Advisory Council on the Misuse of Drugs (ACMD) in June 2014 recommended that ETH-LAD be specifically named in the UK Misuse of Drugs Act as a class A drug. The chemical was listed with other drugs in The Misuse of Drugs Act 1971 (Amendment) (No. 2) Order 201. The drug is legal to be purchased in some countries for research use only.

Research Uses of ETH-LAD

Researchers can use ETH-LAD to develop selective 5-HT2AR modulators and other ETH-LAD analogues to target distinct signaling pathways and neural circuits for treating emotional, neuropsychiatric, learning and memory, spatial cognition, mental disorders and neurodegenerative disorders. Researchers, scientists and research organizations can buy ETH-LAD from online research chemicals supplier with fast shipping and delivery. Note: This compound must be treated with the utmost care and protective gloves must be worn when conducting research experiments.

5-hydroxytryptophan (5-HTP) is a chemical that is produced by human body makes from the amino acid – tryptophan (it is an essential amino acid that you get from food). 5-HTP converted into another chemical called serotonin inside human body. This naturally occurring substance can also be derived from the seed pods of Griffonia simplicifolia, which is a West African medicinal plant. Since 5-HTP is converted into neurotransmitter serotonin, it may have a positive effect on sleep disorders, mood, anxiety, appetite, obesity, headache, depression, and pain sensation.

How does it work?

5-HTP works in the central nervous system by increasing the production of the chemical serotonin. Since 5-HTP increases the synthesis of serotonin, it is used for several medical conditions and diseases where serotonin is believed to play an important role such as depression, insomnia, obesity, and many other conditions. Taking 5-HTP as a supplement can been shown to improve:

Obesity and Appetite

Three studies including “Eating Behavior And Adherence To Dietary Prescriptions In Obese Adult Subjects Treated With 5-hydroxytryptophan” have shown that 5-HTP appears to have a fairly effective impact on appetite, which tends to reduce food intake and obesity problem.

Insomnia and Sleep Terrors

One clinical trial suggests reductions in sleep terrors when 5-HTP is taken as supplementation. The study “L -5-Hydroxytryptophan Treatment Of Sleep Terrors In Children” has found that when taken during bedtime, 5-HTP can reduce sleep terror problem in children. Numerous double-blind clinical studies have revealed that the chemical can decrease the time required to get to sleep and the number of awakenings in adults.

Depression and Anxiety

Preliminary studies indicate that 5-HTP may also work well in the treatment of people with mild-to-moderate depression and anxiety. 5-HTP has been found to have similar effects like the class of antidepressants – selective serotonin reuptake inhibitors (SSRIs) on the brain. One study compared the effects of 5-HTP to fluvoxamine (Luvox) and found that participants who were given 5-HTP did just as well as those who receive Luvox.

Mood Enhancement and Energy Level

5-HTP can combine synergistically with DHEA and phenylalanine to enhance mood while boosting energy level. They are really helpful in counteracting the age-related decline of the neurotransmitters serotonin and noradrenaline, thus enabling people to avoid mood swings and also maintain energy as they age.

Fibromyalgia

Taking 5-HTP has been shown to improve symptoms of fibromyalgia including pain severity, morning stiffness, and sleeplessness. In one double-blind study, 50 patients with fibromyalgia were given either 5-HTP (100 mg) or a placebo three times per day. The group that received the 5-HTP experienced significant improvements in Fibromyalgia symptoms while the group that received the placebo did not improve much at all.

5-HTP is known to provide many benefits, however, several advanced research are required to be conducted to understand its other benefits for people with differing personal needs. Scientists and research organisations need to buy 5-HTP serotonin research chemical for their in-vivo research to understand its effects on human brain. Buy legal research chemical from online stores to know how 5-HTP can be used in pharmacotherapy.

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