From 1828 he was director of the Rouen Museum of
Natural History and the Rouen Jardin des Plantes. Later, in
1838, he became professor at the School of Medicine at Rouen. His
major scientific work Hétérogénie was published in 1859.
He also wrote a layperson's encyclopedia The Universe,
published in 1870, which gives an overview of the sciences, but in
which Pouchet ridicules Louis Pasteur's theories (calling them panspermism) and atomic theory.

In 1847 Felix-Archimede Pouchet effectively launched the study
of the physiology of cytology[2].