Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Additionally we are shipping MICAL3 Proteins (2) and many more products for this protein.

More Antibodies against MICAL3 Interaction Partners

MICAL3 acts as a midbody-associated scaffold for vesicle targeting, which promotes maturation of the intercellular bridge and abscission.

Further exploration of the NINL (show NINL Antibodies)-associated interactome identifies MICAL3, a protein known to interact with Rab8 (show RAB8A Antibodies) and to play an important role in vesicle docking and fusion.

data do not support our hypothesis that the association between rs2277831 and primary osteoarthriti is due to the effect this SNP has on MICAL3, BCL2L13 (show BCL2L13 Antibodies) or BID (show BID Antibodies) gene expression

The monooxygenase activity of MICAL3 is required to regulate its own turnover and the concomitant remodeling of vesicle-docking protein (show USO1 Antibodies) complexes.

MICAL3 Antigen Profile

Protein Summary

Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization (By similarity). Involved in is required for this process.