This textbook on haematology in the Illustrated Colour Text series is suitable for medical students, junior doctors and others needing a concise and practical introduction to the subject. Concise and manageable coverage of the major blood diseases and their treatment. Does not overload the reader with science, unlike some competing books. Focus is on the haematology patient and on the practical aspects of the subject. Makes use of the attractive features of the ICT series - double page spreads, lots of colour illustrations, summary boxes.

Hematology Case Studies with Blood Cell Morphology and Pathophysiology compiles specialized case studies with specific information on various hematological disorders with Full Blood Examination (FBE or CBC), blood film images and pathophysiology of each condition. In addition, it provides basic information on how to recognize and diagnose hematological conditions that are frequently observed in the laboratory. Technicians and scientists working in core laboratories such as biochemistry labs or blood banks will find this book to be extremely thorough. Moreover, it can be used as a reference book by technicians, scientists and hematologists in every level of expertise in diagnosing hematological disorders.

An investigation into the types, physiological sources, and cultural resonances of hallucinations, this book traces everything from the disorientations of sleep and intoxication to the manifestations of injury and illness. ... Hallucinations ... are linked to sensory deprivation, intoxication, illness, or injury. People with migraines may see shimmering arcs of light or tiny, Lilliputian figures of animals and people. People with failing eyesight, paradoxically, may become immersed in a hallucinatory visual world. Hallucinations can be brought on by a simple fever or even the act of waking or falling asleep, when people have visions ranging from luminous blobs of color to beautifully detailed faces or terrifying ogres. Those who are bereaved may receive comforting "visits" from the departed. In some conditions, hallucinations can lead to religious epiphanies or even the feeling of leaving one's own body. Humans ... have used hallucinogenic compounds to achieve [such life-changing visions]. As a young doctor in California in the 1960s, the author had both a personal and a professional interest in psychedelics. These, along with his early migraine experiences, launched a lifelong investigation into the varieties of hallucinatory experience. Here, he weaves together stories of his patients and of his own mind-altering experiences to illuminate what hallucinations tell us about the organization and structure of our brains, how they have influenced every culture's folklore and art, and why the potential for hallucination is present in us all, a vital part of the human condition. --Excerpted from book jacket.

Employing a unique case-based approach, Ham's Primary Care Geriatrics continues to be your comprehensive source of clinical solutions for this challenging population. This gerontology medical reference book features an interdisciplinary perspective that empowers you with team-oriented knowledge on the best diagnosis, treatment, and management strategies available to address the complex needs of older adults. Effectively treat your geriatric patients, and provide helpful guidance to their families, through engaging geriatric case studies that illustrate the principles and key clinical information you need. Form a definitive diagnosis and create the best treatment plans possible using the evidence-based medicine guidelines throughout. Find the information you need quickly and efficiently with a 2-color layout and consistent format, and test your knowledge with USMLE-style questions in every chapter.

Injuries to the hamstring and quadriceps muscles can occur in both low- and high-impact sports and as such are among the more common injuries incurred by athletes. Reviewing the relevant physiology, epidemiology, mechanisms, clinical presentation and treatment of these conditions, Hamstring and Quadriceps Injuries in Athletes covers all sports-related injuries of the thigh musculature in one place. Topics covered include mid substance injuries, acute proximal tendon avulsions and harvesting of hamstrings, as well as strains, contusions and ruptures of the quadriceps, including the use of biologic enhancing agents in healing. Chapters on rehabilitation and injury prevention present techniques to maximize recovery and minimize long-term impairment, speeding up return to play. It will be an often-used and reliable guide for sports medicine practitioners, orthopedists, physical therapists, primary care physicians, team physicians and trainers who treat the injured athlete.

This book presents the human hand from an overall perspective from the first appearance of hand-like structures in the fins of big fishes living millions of years ago to today's and the future s mind-controlled artificial hands. Much focus is given to the extremely well-developed sensation of the hand, its importance and its linkage to brain plasticity mechanisms. How can active hands rapidly expand their representational area in the brain? How can the sense of touch substitute for other deficient senses, such as in Braille reading where hand sensation substitutes for missing vision? How can the mere observation of active hands, belonging to others, activate the hand area in the observer's own brain and what is the importance of this phenomenon for learning by imitation and the understanding of other peoples actions, gestures and body language? Why are some of us left-handed and what are the consequences from cultural and physiological viewpoints? Why does phantom sensation and phantom pain occur after hand amputation, and what can we do about it? Why can salamanders regenerate new extremities while humans can not? Is it possible to transplant a hand from a diseased individual to an amputee? Can artificial robotic hands be controlled by our mind, and can they ever gain the role of a normal hand? What role did the hand and the brain play during evolution in tool construction and development of language and cognitive functions? The hand has a high symbolic value in religion, literature and art and our hands have a key role in gestures and body language. The Hand and the Brain is aimed at anybody with interest in life sciences, in the medical field especially hand surgeons, orthopaedic specialists, neurologists and general practitioners, and those working in rehabilitation medicine and pain treatment.

This volume in the Procedures in Reconstructive Surgery Series covers the key hand and upper extremity reconstruction techniques you need to stay on the cutting edge of this rapidly evolving specialty. Experts clearly explain how to perform procedures, sharing ₃tricks of the trade₄ and clinical pearls so you can offer your patients superior results. Each book uses a concise, consistent format that complements the commentary and procedures in operative clips on the accompanying DVD. Master essential reconstructive surgical techniques with the comprehensive titles in this series! Provides real-life clinical details and clear visual guidance to the different operative steps with full-color illustrations and original artwork. Offers complete coverage of reconstructive techniques provided by well-recognized international authorities to provide balanced and comprehensive perspectives. Discusses common pitfalls, emphasizing optimizing outcomes, to refine the quality of your technique. Presents a DVD of video clips of key procedures performed by experts to show you how to enhance your skills.

Accurate assessment of hand function is critical to any treatment regimen of the hand compromised patient. Hand Function is a practical, clinical book which provides the knowledge needed to distinguish the different dimensions of hand function, particularly impairment, disability and handicap. Beginning with an overview of basic principles and examination, subsequent chaptersevaluate the hand function inspecific afflicted populations, including the rheumatoid patient, the stroke patient, the trauma patient, the geriatric patient and the pediatric patient, as well as special populations such asdiabetes mellitus patients and musicians. An appendix containing hand function scales essential to theassessment ofdisability is also included. Rheumatologists, physiatrists, hand surgeons, orthopedists, occupational therapistsand physical therapists will all find Hand Function a useful and valuable addition to their clinical references.

This book is a direct response to a severe treatment gap in recognising, treating and managing attention deficit hyperactivity disorder (ADHD) in adults. Affecting 34% of the global population, ADHD has long been considered a pediatric psychiatric condition and continues to be overlooked in adults, who often go on to endure a lifetime of clinically significant impairments that affect work performance, social behavior, and personal relationships. However, in the wake of the recognition of ADHD in adults in the Diagnostic and Statistical Manual of Mental Disorders IV (considered the absolute gold standard in psychiatry) and a greater number of pharmaceutical treatments being indicated for adults, this book will increase awareness of the condition and advocate expanding ADHD treatment across all age ranges. The book is especially relevant to psychiatrists, GPs, and specialist psychiatric nurses , while also a useful resource for patient societies and advocacy groups.

"Handbook for HIPAA-HITECH Security details the final regulations brought about by HITECH changes to the HIPAA security rule and to the privacy rule as it applies to security. Learn practical and pragmatic ways to interpret the new regulations and ensure compliance." -- Provided by publisher

The field of culture and psychology is one of the fastest growing areas in the social sciences. The 'Handbook of Advances in Culture and Psychology', Volume 6 belongs to an annual series that is the first to offer state-of-the-art reviews of scholarly research programs in this burgeoning field.

There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental and clinical processes of anticancer drug development, creating a single indispensable reference that covers all the steps from the identification of cancer-specific molecular targets to screening techniques and the development and validation of bioanalytical methods to clinical trial design and all phases of clinical trials. The authors have included new material on phase 0 trials in oncology, organ dysfunction trials, drug formulations and their impact on anticancer drug PK/PD including strategies to improve drug delivery, pharmacogenomics and cancer therapy, high throughput platforms in drug metabolism and transport pharmacogenetics, imaging in drug development and nanotechnology in cancer. Authoritative and up-to-date, Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, 2nd Edition provides in one comprehensive and highly practical volume a detailed step-by-step guide to the successful design and approval of anticancer drugs. Road map to anticancer drug development from discovery to NDA submission Discussion of molecular targets and preclinical screening Development and validation of bioanalytical methods Chapters on clinical trial design and phase 0, I, II, III clinical trials Pharmacokinetics, pharmacodynamics, pharmacogenomics, and pharmacogenetics of anticancer agents Review of the drug development process from both laboratory and clinical perspectives New technological advances in imaging, high throughput platforms, and nanotechnology in anticancer drug development.

"In this book the editors aim to disseminate important data pertaining to the modulatory effects of foods and nutritional substances on behavior and neurological pathways and visa versa. This ranges from the neuroendocrine control of feeding to the effects of disease on the brain. The importance of this book pertains to the fact that food is an essential component of cultural heritage but the effects of perturbations in the food-cognitive axis can be quite profound. The complex inter-relationship between neuropsychological processing, diet and beharioural outcome is explored within the context of the most contemporary psychobiological research in the area. This comprehensive psychobiologically and pathology-themed text examines the broad spectrum of diet, behavioural and neuropsychological interactions from normative function to occurrences of severe and enduring psychopathology. The editors have taken a scientific and objective stand and included chapters that scrutinize the relationships between the brain, behaviour, food and nutrition in a scientific and rational way"--Preface.

"Offering a molecular perspective not available 20 years ago, [this edition] provides physical and chemical data on proteins, nucleic acids, lipids, and carbohydrates. Presented in an organized, concise, and simple-to-use format, this popular reference allows quick access to the most frequently used data. Covering a wide range of topics, from classical biochemistry to proteomics and genomics, it also details the properties of commonly used biochemicals, laboratory solvents, and reagents." --excerpts from book jacket.

Technologies for discovery of biomarkers -- Biomarkers and molecular diagnostics -- Biomarkers for drug discovery and development -- Role of biomarkers in health care -- Biomarkers of cancer -- Biomarkers of disorders of the nervous system -- Biomarkers of cardiovascular disorders -- Biomarkers and personalized medicine -- Regulatory issues.

Fully revised and updated, the Handbook serves as a practical guide to endovascular methods and as a concise reference for neurovascular anatomy and published data about cerebrovascular disease from a neurointerventionalist's perspective. Divided into three parts, the book covers:* Fundamentals of neurovascular anatomy and basic angiographic techniques; * Interventional Techniques and endovascular methods, along with useful device information and tips and tricks for daily practice; * Specific Disease States, with essential clinical information about commonly encountered conditions.New features in the 2nd Edition include:* Global Gems that illuminate aspects of the field outside the United States;* Angio-anatomic and angio-pathologic image correlates;* Newly released clinical study results influencing neurointerventional practice;* Information on emerging technologies in this rapidly advancing field.The Handbook is a vital resource for all clinicians involved in neurointerventional practice, including radiologists, neurosurgeons, neurologists, cardiologists, and vascular surgeons.

This concise, clinically focused pocket handbook assembles and synthesizes the latest developments and trends in the diagnosis and treatment of CML and provides an authoritative and convenient summary of the latest progress in TKI trials, the molecular monitoring of CML responses, and the development of new therapies to overcome resistance and improve patient care. Chronic myeloid leukemia (CML) is a rare type of leukemia (1?2 per 100,000 people) but is the most common chronic myeloproliferative neoplasm. CML remains a key model for the improved understanding of the pathophysiology of a malignancy at a molecular level; CML was the first cancer to be associated with a recurring chromosome abnormality, which generates the Philadelphia (Ph) chromosome and its associated fusion gene BCR-ABL1. The clinical outcome for patients with CML has changed dramatically in the past 15 years and this has been due to the development of tyrosine kinase inhibitors (TKIs), compounds that inhibit the activity of the oncogenic BCR-ABL1 protein. A number of first-, second- and third-generation TKIs are now available for the treatment of CML, although a number of treatment challenges remain, not least the development of treatment-resistant CML. Parallel to the development of specific drugs for treating CML, major advances have been made in the field of disease monitoring and standardization of response criteria.

"The Handbook of Clinical Anesthesia, Seventh Edition, is a companion to the parent textbook, Clinical Anesthesia, Seventh Edition. This widely acclaimed reference parallels the textbook and presents content in a concise outline format with additional appendices. The Handbook makes liberal use of tables, graphics, and clinical pearls, to enhance rapid access of the subject matter. This comprehensive, pocket-sized reference guides you through virtually every aspect of perioperative, intraoperative, and postoperative patient care."--Provided by publisher.

Gender medicine is an important new field in health and disease. It is derived from top-quality research and encompasses the biological and social determinants that underlie the susceptibility to disease and its consequences. In the future, consideration of the role of gender will undoubtedly become an integral feature of all research and clinical care. Defining the role of gender in medicine requires a broad perspective on biology and diverse skills in biomedical and social sciences. When these scientific disciplines come together, a revolution in medical care is in the making. Covering twelve different areas of medicine, the practical and useful "Handbook of Clinical Gender Medicine" provides up-to-date information on the role of gender in the clinical presentation, diagnosis, and management of a wide range of common diseases. The contributing authors of this handbook are all experts who, in well-referenced chapters, cogently and concisely explain how incorporation of gender issues into research can affect the medical understanding and treatment of heart disease, osteoporosis, arthritis, pain, violence, and malaria among other conditions. This intriguing and unique medical textbook provides readers with a valuable new perspective to understand biology and incorporate gender issues into the different branches of medicine

This is the new and fully revised third edition of the well-received text that is the benchmark book in the field of nutrition and aging. The editors (specialists in geriatric nutrition, medical sociology, and clinical nutrition, respectively) and contributors (a panel of recognized academic nutritionists, geriatricians, clinicians, and other scientists) have added a number of new chapters and have thoroughly updated the widely acclaimed second edition. This third edition provides fresh perspectives and the latest scientific and clinical developments on the interaction of nutrition with age-associated disease and provides practical, evidence-based options to enhance this at-risk population?s potential for optimal health and disease prevention. Chapters on a wide range of topics, such as the role of nutrition in physical and cognitive function, and coverage of an array of clinical conditions (obesity, diabetes, heart failure, cancer, kidney disease, osteoporosis), compliment chapters on food insecurity, anti-aging and nutritional supplements, making this third edition uniquely different from previous editions. Handbook of Clinical Nutrition and Aging, Third Edition, is a practical and comprehensive resource and an invaluable guide to nutritionists, physicians, nurses, social workers and others who provide health care for the ever-increasing aging population.

Handbook of Clinical Nutrition and Stroke is a comprehensive reference on nutrition for the multidisciplinary team caring for stroke patients. Targeting physicians, nurse practitioners, clinical dietitians, and advanced allied health and medical students, this volume provides an introduction on the different types of stroke, associated risk factors, and uniquely featured global perspectives on stroke. In addition to discussing stroke risk factors, the book expands upon treatment and management from the acute care setting through rehabilitation, captures the lifespan of patients affected by stroke.

Growing recognition of the role of behavioral health in overall health, the rise of health psychology, the trend toward interdisciplinary medicine--any number of factors have made clinical psychology an integral part of integrative care. Its applicability to the range of specialties, populations, and levels of care adds to its increasing necessity in diverse healthcare settings. The Handbook of Clinical Psychology in Medical Settings emphasizes evidence-based care and practical strategies for hands-on work with patients while illuminating the unique aspects of the practice of psychology within medical settings. Skills are examined in depth for more effective work with patients, more efficient teamwork with colleagues, and better functioning within medical settings, whether readers are involved in primary, secondary, or tertiary care or prevention. Chapters also focus on ethical, legal, and financial issues, as well as changes needed in training programs to ensure that the field keeps up with the evolution of care systems and service delivery. Included in the Handbook 's forward-looking coverage: Psychology and population health. Core competencies for success in medical settings. Evidence-based practice--and practice-based evidence. Marketing health psychology, both within and outside the medical setting. Competency for diverse populations. Plus chapters devoted to specific specialties and settings, from cardiology to women's health. Comprehensive yet highly readable, the Handbook of Clinical Psychology in Medical Settings is a practice-building resource for health psychologists, clinical psychologists, and primary care physicians.

Introduction -- How to become a learner-centered teacher -- How to optimize teaching by using observation and feedback -- How to use learning preferences to optimize teaching effectiveness -- How to effectively teach millennials: understanding intergenerational factors -- How to use reflective and deliberate practice to maximize learning -- How to use teaching scripts to make teaching more effective and efficient -- How to give a great PowerPoint presentation -- How to give a great "chalk talk" -- How to teach at the bedside -- How to teach beginning students in the clinical setting -- How to teach medical students in an ambulatory clinic -- How to teach in free clinics: brief encounters with learners and patients in vulnerable communities -- How to teach students on an inpatient clerkship -- How to use Entrustable Professional Activities to evaluate and teach physician trainees -- How to teach in the emergency department -- How to teach in the operating room -- How to teach procedures -- How to teach quality improvement and patient safety -- How to teach fundamental communication skills -- How to teach clinical reasoning -- How to teach communication skills for palliative care conversations -- How to teach error disclosure to students and residents -- How to remediate learners on a short clinical rotation: getting the learner back on track -- How to give difficult feedback -- How to teach physical examination -- How to teach interprofessional learners.

This book promotes an evidence-based paradigm of fetal heart rate monitoring during labour, with a move away from the traditional 'pattern-based' interpretation to physiology-based interpretation. Chapters are presented in a systematic and accessible format, covering topics such as non-hypoxic causes of fetal brain injury, pre-existing hypoxia, types of intrapartum hypoxia, erroneous monitoring of maternal heart rate, fetal scalp blood sampling and fetal ECG (STAN), intermittent auscultation and medico-legal issues. Sections on 'pearls' and 'pitfalls' highlight good practice and common errors to promote best practice. End-of-chapter exercises allow the reader to engage with the theory and test their knowledge of key areas. This is a highly practical manual aimed at obstetricians and midwives, particularly those undergoing CTG training. The book will also be very useful to midwifery and medical students and to all those involved in multiprofessional intrapartum care.

Introduction : remembering as a psychological and social-cultural process / Brady Wagoner -- Part I. Concept and history of memory. The evolutionary origins of human cultural memory / Merlin Donald -- From memory as archive to remembering as conversation / Jens Brockmeier -- Discerning the history inscribed within : significant sites of the narrative unconscious / Mark Freeman -- Part II. Cultural contexts of remembering. The landscape of family memory / Bradd Shore and Sara Kauko -- Materiality of memory : the case of the remembrance poppy / Kyoko Murakami -- Approaches to testimony : two current views and beyond / Kotaro Takagi and Naohisa Mori -- Rethinking function, self, and culture in "difficult" autobiographical memories / Steve D. Brown and Paula Reavey -- Part III. Memory through the life course. The cultural construction of memory in early childhood / Katherine Nelson -- Memory in life transitions / Constance de Saint Laurent and Tania Zittoun -- Memory in old age : a lifespan perspective / Dieter Ferring -- Part IV. Memory, history, and identity. National memory and where to find it / James V. Wertsch -- History, collective memories, or national memories? : how the representation of the past is framed by master narratives / Mario Carretero and Floor van Alphen -- Media and the dynamics of memory : from cultural paradigms to transcultural premediation / Astrid Erll.

Depression is a common mood disorder that affects approximately 10% of the global population at some point in their lives and can cause serious psychological, physical, and cognitive distress. Additionally, patients with depression are at a greater risk for cardiovascular disease, stroke, functional impairment, disability and all-cause mortality. Aside from the impact on the individual, this condition presents a very real economic burden, as depression is the most predominant mental health problem among working-age patients and the leading cause of lost work productivity. Despite advances in screening and treating depression in recent decades, a vast majority of patients with depression do not actively seek treatment and, of those that do, only a quarter have been found to receive adequate and effective interventions. Handbook of Depression, Second Edition is a concise review of assessment tools, available and emerging pharmacological and non-pharmacological treatment options, and consensus management guidelines that center on enhancing the clinician-patient relationship and improving patient quality of life. Cowritten by expert US- and UK-based authors, this handbook has an innovative global focus that consolidates current knowledge in a convenient, pocket-sized guide that is ideal for every day reference in a clinical setting.

The Handbook of Dermatologic Surgery incorporates the most cutting edge technology applicable to dermatologists and dermatologic surgeons today. Designed as a reference guide for dermatologic surgery and aesthetic procedures, it disseminates key scientific information in an easy-to-use pocket book. This handbook is designed to be readily transportable for dermatologists and dermatologic surgeons, as well as those in training, dermatology residents and fellows, and medical students rotating through dermatology.

Reference to quantitative measures of quality of life, life expectancy, and the financial costs of illness and treatment. Features in-depth reviews of disability-adjusted life years (DALYs), quality-adjusted life years (QALYs), quality of life and financial measures for over 120 diseases and conditions.

"This book draws together recent data on both cytoplasmic and flagellar dyneins and the proteins they interact with, to give readers a clear picture of what is currently known about the structure and mechanics of these remarkable macro-molecular machines. Each chapter is written by active researchers, with a focus on currently used biophysical, biochemical, and cell biological methods. This is a useful handbook for frontline researchers as well as a textbook for advanced students."--P. [4] of cover.

Handbook of Endovascular Interventions presents a step-wise approach to the techniques of peripheral vascular interventions. Covering interventions in all major organ systems, this concise and comprehensive resource provides the rationale on why these approaches have been adopted by most practicing vascular interventionalists. This volume also presents key information on intervention techniques and pitfalls, complications and their management, surgical management options, as well as landmark papers on the topic. Unique to this book is the inclusion of sections building an endovascular suite, and coding as well as international training paradigms across the globe.Authored by international experts from around the globe, Handbook of Endovascular Interventions is a true how-to book for the busy interventionalist.

This updated and revised edition of the classic bedside pocket reference remains the gold standard in critical care medicine. The new edition maintains Dr. Marik's trademark humor and engaging writing style, while adding numerous references to make this book the most current and thorough treatment of evidence-based critical care available. The handbook enables the clinician to find the evidence to support or refute an intervention and to help choose the most appropriate, cost-effective treatment. The analysis of treatment strategies is presented by organ system, and the handbook also covers miscellaneous ICU topics (such as sedation, toxicology, radiology, and sepsis) based on the most frequently found and difficult to solve problems in ICU patient management.

Part I. Duties of forensic medicine in modern societies -- Part II. Medical aspects of death -- Part III. Traumatology and violent death -- Part IV. Sudden and unexpected death from natural causes -- Part V. Clinical forensic medicine -- Part VI. Forensic psychiatry -- Part VII. Toxicology -- Part VIII. Traffic medicine -- Part IX. Identification -- Part X. The doctor and the law -- Part XI. Insurance medicine.

Growth is one of the human bodys most intricate processes: each body part or region has its own unique growth patterns. Yet at the individual and population levels, growth patterns are sensitive to adverse conditions, genetic predispositions, and environmental changes. And despite the bodys capacity to compensate for these developmental setbacks, the effects may be far-reaching, even life-long. The Handbook of Growth and Growth Monitoring in Health and Disease brings this significant and complex field together in one comprehensive volume: impact of adverse variables on growth patterns; issues at different stages of prenatal development, childhood, and adolescence; aspects of catch-up growth, endocrine regulation, and sexual maturation; screening and assessment methods; and international perspectives. Tables and diagrams, applications to other areas of health and disease, and summary points help make the information easier to retain. Together, these 140 self-contained chapters in 15 sections [ok?] cover every area of human growth, including:Intrauterine growth retardation.Postnatal growth in normal and abnormal situations.Cells and growth of tissues.Sensory growth and development.Effects of disease on growth.Methods and standards for assessment of growth, and more. The Handbook of Growth and Growth Monitoring in Health and Disease is an invaluable addition to the reference libraries of a wide range of health professionals, among them health scientists, physicians, physiologists, nutritionists, dieticians, nurses, public health researchers, epidemiologists, exercise physiologists, and physical therapists. It is also useful to college-level students and faculty in the health disciplines, and to policymakers and health economists.

"A resource covering the delivery of all healthcare services, this handbook provides the collective source to promote and facilitate integrated system solutions for healthcare. Written from a systems engineering perspective, it provides theoretical foundations, methodologies, and case studies in each main sector of healthcare delivery systems for designing, assessing, optimizing, and managing each healthcare outcome. It covers the state-of-the-art in modern technologies and offers a comprehensive description of the healthcare delivery system from the macro level (e.g. hospitals) to the micro level (e.g. operation room)"--Provided by publisher.

"Human oocyte cryopreservation has undergone rapid growth, with technical improvement and increasing clinical application over the last ten years. Storing eggs is ethical and gives many young women their most realistic chance of conception. Cryopreservation, however, is still considered by many as an experimental technique and conflicting reports are published as to its efficacy. For these reasons, it is necessary to give reproductive researchers and practitioners comprehensive and systematic information about the field. This book describes and analyses the history of human oocyte freezing, the main steps of technical evolution, and the pros and cons of different techniques. In addition, the clinical applications, long-term outcome, efficiency and safety of oocyte cryopreservation are detailed. The Handbook of Human Oocyte Cryopreservation gives a complete picture of the field today and is a valuable text for embryologists, cryobiologists, reproductive medicine practitioners and anyone involved in researching and implementing the technique"--Provided by publisher.

edited by John Fuller, MD, FRCP, Professor in the Department of Anesthesia and Perioperative Medicine, and Division of Critical Care (Department of Medicine), Western University, London, ON, Jeff Granton, MD, FRCP, Associate Professor in the Department of Anesthesia and Perioperative Medicine, and Division of Critical Care (Department of Medicine), Western University, London, ON, Ian McConachie, MB, ChB, FRCA, FRCP, Associate Professor in the Department of Anesthesia and Perioperative Medicine, and Division of Critical Care (Department of Medicine), Western University, London, ON.

"This bestseller has been an essential book for all those working with laboratory animals since it was first published in 1994. This fourth edition retains all the classic features that have made it a must-have reference including emphasis on best practice in order to improve animal welfare. The contents have been thoroughly updated and reorganised to make sure it is a really practical book for day-to-day use in the laboratory. The first section of the book covers principles applicable to all species, for example husbandry, handling and the education and training required by scientists and technical staff working with animals in the laboratory. Later chapters focus on specific species or groups of species. New to this edition: Reflects changes in European legislation and their impact on national legislation. Covers recommendations for the education and training of those carrying out animal experiments across Europe. New chapters on ethical considerations and balancing animal welfare with science. New information on environmental enrichment for laboratory animals. Covers advancements in anaesthesia and analgesia and techniques. Spiral bound for ease-of-use as a bench-top reference. This book is ideal for all personnel carrying out scientific procedures using animals, particularly during training and also for the new researcher. It will also be essential reading for study directors designing research programmes, animal technicians and veterinarians working with laboratory animal species"--Provided by publisher.

Dramatic improvements in laser technology have yielded new indications and applications in cutaneous disorders. Existing texts covering lasers in dermatology are often bulky and therefore it has been hard for the dermatologist to find a complete and concise reference that highlights only the specific use of lasers in cutaneous medicine. This handbook has been written to provide a basic structural framework for clinicians and trainees, and clearly outlines laser techniques for each specific dermatologic disorder. Handbook of Lasers in Dermatology comprehensively covers each application of lasers for the skin in a manner that can be easily read by beginners and experts alike. It provides readers with a handy and reliable reference guide that improves patient care and treatment outcomes. It is therefore of interest to all dermatologists who use lasers in their clinical practice.

Well-organized and vibrantly illustrated throughout, Handbook of Liver Disease is a comprehensive yet concise handbook providing authoritative guidance on key clinical issues in liver disease. The quick-reference outline format ensures that you'll find answers when you need them, and cover-to-cover updates keep you abreast of the recent rapid changes in the field. Written by leading international experts in hepatology, this reference is ideal for gastroenterologists, hepatologists, internists, family practitioners, trainees, and others who diagnose and manage patients with liver disorders.

"Preface Almost 1,800 media are described in the Handbook of Media for Clinical and Public Health Microbiology, including newly described media for the cultivation of emerging pathogens. Diseases caused by emerging pathogens that are responsible for increased rates of morbidity and mortality rates, such as Escherichia coli O157:H7, methicillin resistant Staphylococcus aureus (MRSA), vancomycin resistant enterococci (VRE), and carbapenem resistant enterococci (CRE) have raised special concerns and various media included in the Handbook have been designed for the specific cultivation and identification of these pathogens. Many of the new media included in the Handbook of Media for Clinical and Public Health Microbiology permit the cultivation of bacteria, fungi, and viruses that are currently causing major medical problems around the world. These media are very important for the rapid detection of pathogenic microorganisms and the diagnosis of individuals with specific infectious diseases adn for preventing the spread of pathogens via food, water, and environmental sources. Several of the new media described in the Handbook of Media for Clinical and Public Health Microbiology include chromogenic or fluorogenic substrates that permit the rapid detection of specific pathogens. An important function of the Handbook of Media for Clinical and Public Health Microbiology is to provide descriptions of the media that are used to cultivate and identify microorganisms from clinical specimens and those of public health significance. The Handbook provides a compilation of the formulations, methods of preparation, and applications for media used in clinical and public health microbiology laboratories"--Provided by publisher.

The recent surge of interest in the neuroscience of autism, HIV/AIDS, cancer, Alzheimers, and other disorders has brought with it an increasing awareness of the effects of medical conditions on the brain and behavior-an awareness extending through the research and practice arenas, among those working with pediatric and adult clients alike. Comprehensive in scope and highly detailed in its coverage, the Handbook of Medical Neuropsychology is organized to give readers knowledge of the field, whether one needs to understand a clinical evaluation, design a research study, or gain a deeper understanding of disease processes and corresponding behaviors. Featuring the most up-to-date information on cognitive neuroscience to enhance the work of the practitioner, the student, or the researcher, the book handles theory, historical background, practical considerations, and controversial areas with clear explanations, clinical expertise, and real-world insight, and critiques diagnostic and assessment tools specific to disorders. The wide selection of commonly seen and rarely encountered diagnoses covered includes: . Primary nervous system disease and injury. . Vascular system disease. . Developmental, genetic, and structural disorders. . Dementia and normal aging. . Immune-related disorders. . Endocrine disease. . Metabolic conditions. . Plus a chapter on current and emerging approaches to rehabilitation. Opening out a specialty as it grows in importance, the Handbook of Medical Neuropsychology is an essential resource for the neuropsychology clinician, researcher, or graduate student. It will be stimulating and relevant reading for years to come.

"Reviewing the health applications of selected metallic elements and the inorganic, organic, and bio-chemistry underlying the formulation of metallonutraceuticals, this comprehensive work provides a detailed description of the fundamentals and end-use applications of a series of metals vital to the metabolic and nutritional activities of human beings. Assuming a basic understanding of the role of metals in human physiology, it addresses various production issues including scaling up, processing, and automation from different scientific perspectives, as well as FDA regulations, institutional regulations, and ethics for industrial operations and corporate transactions"--Provided by publisher.

"Reflecting the milestones in the field that have occurred since the publication of the first edition, this book provides an updated tool kit that incorporates conventional as well as modern approaches to tackling biological and medicinal research in the post genomic era. The authors have evaluated, revised, and sometimes replaced all protocols with more efficient, reliable, or simpler ones. The book is also completely reorganized and covers topics of modern "omics" approaches, including genomics, proteomics, and metabolomics. This is followed coverage of the Manipulation of Biological Systems, including RNAi, and the use of microscopy"--Provided by publisher.

Discusses the impact of cultural, ethnic, and racial variables for the assessment, diagnosis, treatment, service delivery, and development of skills for working with culturally diverse populations. This second edition recognizes diversity as extending beyond race and ethnicity to reflect characteristics or experiences related to gender, age, religion, disability, and socioeconomic status.

This handbook is an in-depth and comprehensive guide to the pathophysiology, diagnosis, staging, treatment and management of patients with multiple myeloma. The Handbook was commissioned to address an unmet need for a book of this kind in the myeloma field and to provide busy healthcare professionals with an informative and educational review of the current and emerging treatment recommendations for multiple myeloma. Myeloma is a type of bone marrow cancer arising from plasma cells and is the second most common form of bone marrow cancer, but represents just 1% of all cancers. The causes of myeloma are not fully understood but it is thought to be caused by an interaction of both genetic and environmental factors. This Handbook discusses these issues as well the latest developments in the field and will be an invaluable source of topical information for all healthcare professionals with an interest in multiple myeloma.

Over the past 30 years there have been significant advances in our understanding of multiple sclerosis (MS) due to the use of MRIs to better visualize the disease and because of the introduction of new ameliorating drugs. However, MS is still an incurable disease and diagnosis remains challenging for many physicians; for instance symptoms often mimic MS and there is not a specific test for the disease. To ensure optimal patient care there is a need for physicians to remain up to date with new drugs on the market, disease detection, diagnosis, and latest management options. The Handbook of Multiple Sclerosis (Second Edition) provides a concise, easily assessable guide for all healthcare professionals involved in the diagnosis and management of this condition, including standard therapies, as well as more novel treatments. The book includes comprehensive evaluations of the pharmacological treatments available, including novel investigational agents currently in development.

"Neuroscientists employ many different techniques to observe the activity of the brain, from single-channel recording to functional imaging (fMRI). Many practical books explain how to use these techniques, but in order to extract meaningful information from the results it is necessary to understand the physical and mathematical principles underlying each measurement. This book covers an exhaustive range of techniques, with each chapter focusing on one in particular. Each author, a leading expert, explains exactly which quantity is being measured, the underlying principles at work, and most importantly the precise relationship between the signals measured and neural activity. The book is an important reference for neuroscientists who use these techniques in their own experimental protocols and need to interpret their results precisely; for computational neuroscientists who use such experimental results in their models; and for scientists who want to develop new measurement techniques or enhance existing ones"--Provided by publisher.

Handbook of Neuroemergency Clinical Trials, Second Edition, focuses on the practice of clinical trials in acute neuroscience populations, or what have been called neuroemergencies. Neuroemergencies are complex, life-threatening diseases and disorders, often with devastating consequences, including death or disability. The overall costs are staggering in terms of annual incidence and costs associated with treatment and survival, yet despite their significance as public health issues, there are few drugs and devices available for definitive treatment. The book focuses on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. This volume provides neurologists, neuroscientists, and drug developers with a more complete understanding of the scientific and medical issues of relevance in designing and initiating clinical development plans for novel drugs intended for acute neuroscience populations. The editors provide the best understanding of the pitfalls associated with acute CNS drug development and the best information on how to approach and solve issues that have plagued drug development.

Neuroendocrinology, the discipline concerned with how the nervous system controls hormonal secretion and how hormones control the brain, is pivotal to physiology and medicine. Neuroendocrinology has disclosed and underpins fundamental physiological, molecular biological and genetic principles such as the regulation of gene transcription and translation, the mechanisms of chemical neurotransmission and intracellular and systemic feedback control systems. Reproduction, growth, stress, aggression, metabolism, birth, feeding and drinking and blood pressure are some of the bodily functions that are triggered and/or controlled by neuroendocrine systems. In turn, neuroendocrine dysfunction due to genetic or other deficits can lead, for example, to infertility, impotence, precocious or delayed puberty, defective or excessive growth, obesity and anorexia, Cushing's Syndrome, hypertension or thyroid disorders. These as well as neuroendocrine tumors are some of the themes covered in the 36 chapters of the Handbook. Drafted by internationally acknowledged experts in the field, the Handbook chapters feature detailed up-to-date bibliographies as well as "how do we know?" call out sections that highlight the experimental or technical foundations for major concepts, principles, or methodological advances in each area. Aimed at senior undergraduate and graduate students, post-doctoral fellows and faculty in neuroscience, medicine, endocrinology, psychiatry, psychology and cognate disciplines, the Handbook of Neuroendocrinology satisfies an unmet need that will prove useful at the laboratory bench as well as in the office.

"The evolution of vascular neurosurgery has continued and now provides a new set of tools to treat hemorrhagic and ischemic disease. Clearly, this evolution is becoming mainstream in neurosurgical training and adds to the body of knowledge that currently exists within traditional neurosurgical education."--Excerpt from notes provided by publisher.

Neuroprotection has been placed on a firm scientific basis during the past decade due to an improved understanding of the molecular basis of neurological diseases and the knowledge that treatment of neurological disorders should not be merely symptomatic but preventative against the progression of the underlying disease, as well as regenerative. The Handbook of Neuroprotection serves as a comprehensive review of neuroprotection based on knowledge of the molecular basis of neurological disorders. Neuroprotective effects of older, established drugs, as well as new drugs in development, are well documented in this detailed volume, featuring the most cutting-edge and innovative methods currently in use. In-depth and authoritative, The Handbook of Neuroprotection features a compendium of vital knowledge aimed at providing researchers with an essential reference for this key neurological area of study.

"Beginning with an overview of food and food constituents, the book outlines current nutrient analysis systems, techniques for data analysis, and food labeling. The book reviews nutrition science including terminology, biochemistry, nutrient-nutrient interactions, and comparative nutrition. There is a detailed assessment in section three on nutritional needs throughout the lifecycle. It highlights exercise and the value of vegetarian diets in health promotion and disease prevention. Section four considers issues surrounding nutritional assessment, screening, and monitoring tools including questionnaires, and anthropometric-, psychological-, and energy-assessments--Provided by publisher.

"Now in its third edition, The Handbook of Obesity: Epidemiology, Etiology, and Physiopathology offers comprehensive coverage of the biological, behavioural, and environmental determinants of obesity and how excess weight affects and exacerbates a range of comorbid conditions including diabetes, cardiovascular disease, diabetes, pulmonary function, arthritis, and cancer. The content of this new edition reflects our evolving understanding of the causes and consequences of obesity. The text now constitutes five sections: History and Prevalence, Biological Determinants, Behavioural Determinants, Environmental, Social, and Cultural determinants, Consequences of Obesity. We now have a much better understanding of internal, biological factors associated with the development of obesity and the new edition dedicates 18 chapters to discussing the role of internal mechanisms on weight gain including chapters discussing genotype, early fetal life and events, the regulation of energy balance, the role of adipose tissue, and energy costs, among others. The role of our individual behaviours and degrees to which these, as well as larger cultural and environmental factors, influence our eating and weight issues is now also better understood thanks to increased research. These sections look at the likes of our work culture, drinking, sleep duration, and changing eating behaviours, as well as government-level food policies, changing advertising practices, economic determinants, and cultural traits relating to weight gain. Finally, we are now increasingly aware of the damage excess weight has on our bodies and the role it plays in the development of disease. The many diseases that have obesity as important risk factors are discussed in 15 chapters and include heart disease, diabetes, metabolic syndrome, cancer, liver disease, and pulmonary function"--Provided by publisher.

Occupational safety and health--safe work in a safe environment. The challenge, of course, is how to make this happen and make it happen economically. A comprehensive study presenting the state of the art in the field, Handbook of Occupational Safety and Health provides a wide range of methods along with specific criteria for assessing hazards and exposures in the workplace environment. More importantly, it also offers ways to reduce these hazards. The book supplies a compendium of interdisciplinary knowledge that includes physical, chemical, and psychosocial risk factors in the work environment and also discusses issues concerning occupational safety and health management. The book discusses the ergonomic principles of shaping products, workstands, and work processes, highlighting the significance of international requirements for competitiveness in the world economy. It presents the scientific basis for each safety and health issue, followed by well-illustrated case studies to demonstrate the concepts and theories and their application in real-world situations. Based on the results of international research, the book covers. Developed by a team of renowned contributors, Handbook of Occupational Safety and Health includes strategies for creating safe working conditions, accurately assessing hazards posed by harmful environmental factors, and preventing occupational accidents and diseases. Meticulously designed to be user-friendly, it provides the tools to create a safety culture beginning at the enterprise level through to the individual employee. --Book Jacket.

"This handbook presents methods that improve the accuracy in glucose prediction based on infrared absorption spectroscopy, recent studies on the influence of acute hyperglycemia on cerebral blood flow, and the correlation between diabetes and the thermo-optical response of human skin. It examines skin glucose monitoring by near-infrared spectroscopy (NIR), fluorescence-based glucose biosensors, and a photonic crystal contact lens sensor. The contributors also explore problems of polarimetric glucose sensing in transparent and turbid tissues as well as offer a high-resolution optical technique for noninvasive, continuous, and accurate blood glucose monitoring and glucose diffusion measurement."--BOOK JACKET.

This book covers a wide range of disorders such as atrial fibrillation, artificial heart valves, deep vein thrombosis, pulmonary embolism and stroke. Handbook of Oral Anticoagulation aims to provide an accessible overview of the exciting new developments in this field. Incorporating numerous quick-reference tables and figures and fully referenced throughout to key papers and the latest reviews, it will be a useful resource for all healthcare professionals involved in thromboprophylaxis.

This handbook provides a short, contemporary text on the management of dentofacial deformities. The importance of a well organised, inter-disciplinary approach is emphasised throughout and the following key areas are presented: A detailed account of the role of the psychologist, from initial assessment through to post-operative support. A systematic approach to dentofacial assessment, including a section on diagnostic records and an overview of cephalometry. A logical step-by-step approach to treatment planning, emphasising the interactive thought process required.

Handbook of Pain and Palliative Care:Biobehavioral Approaches for the Life Course Rhonda J. Moore, editor Chronic pain sends millions to doctors every year{u2014}yet for many, due to professional caution, incomplete assessment, or other reasons, their treatment is less than adequate in relieving their suffering. With the rise of integrative perspectives and the emphasis on overall quality of life rather than discrete symptoms, pain management is gaining importance across medical disciplines. The Handbook of Pain and Palliative Care meets the needs of this growing field by taking both a biobehavioral and a lifespan approach to understanding long-term and chronic pain and intervening to improve patients{u2019} optimal functioning. Rich in clinical diversity, chapters explore emerging areas of interest (computer-based interventions, fibromyalgia, stress), ongoing concerns (cancer pain, low back pain), and special populations (pediatric, elders, veterans). This coverage provides readers with a knowledge base in assessment, treatment, and management that is up-to-date, practice-strengthening, and forward-looking. Subject areas featured in the Handbook Patient/practitioner communication. Assessment tools and strategies. Common pain conditions across the lifespan. Biobehavioral mechanisms of chronic pain. Pharmaceutical, neurological, and rehabilitative interventions. Psychosocial, complementary/alternative, narrative, and spiritual approaches. Ethical issues and future directions. The Handbook of Pain and Palliative Care stands out as a one-stop reference for a range of professionals, including health practitioners specializing in pain management or palliative care, clinical and health psychologists, public health professionals, and clinicians and administrators in long-term care and hospice.

"This pathophysiology handbook is ideally suited for easy reference in the classroom or clinical environment. The book presents a summary of physiology concepts for each body system, followed by an overview of important pathophysiology concepts related to 'alterations' in that body system. These pathophysiology concepts provide the necessary foundation for understanding the disease or injury states that are presented next in the chapter"--Provided by publisher.

Pathologists have long recognized that pediatric autopsy requires great care in technique and dissection to ensure that easily overlooked malformations are recognized and accurate diagnoses are made. The highly experienced authors have created a new edition of Handbook of Pediatric Autopsy Pathology, a comprehensive reference guide to the actual performance of the pediatric autopsy and the optimal recognition and interpretation of pathologic findings. The Handbook of Pediatric Autopsy Pathology, Second Edition covers the spectrum of pediatric pathology with particular reference to those conditions that can be identified at autopsy. New and updated material includes microbiological studies, particularly with the advent of newly described micro-organisms causing disease. The volume also addresses new developments in metabolic diseases, new techniques of ultrasound imaging, and specialized laboratory testing. Furthermore, the book provides a wealth of practical information and bibliographic citations throughout, new copious illustrations and line drawings, numerous standard reference tables, and appendices at the end of multiple chapters. Authored by authorities in the field, Handbook of Pediatric Autopsy Pathology, Second Edition is a valuable resource that will assist general and pediatric pathologists, neonatologists, interns and residents in training, as well as specialists in cytogenetics and ultrasound technicians in understanding the manner and cause of death in its broadest and comprehensive sense.

With just over half a decade passing since the first edition of the Handbook of Pediatric Cardiovascular Drugs was published, it remains the only book of its nature to provide health care practitioners with a tool to safely and consistently prescribe and administer cardiovascular drugs in children with cardiac disease. In this new edition, the editors have updated this important resource in collaboration with highly reputed authors. This pocket reference handbook remains tailored to help cardiovascular practitioners meet the daily challenges of caring forpatients, from the newborn to the young adult, with cardiac disease. In addition to providing an extensive review of all cardiovascular medications, the Handbook of Pediatric Cardiovascular Drugs, 2nd Edition also discusses the information required to assist caregivers in their daily clinical practice. Physicians, fellows, residents, nurse practitioners, physician assistants, pharmacists, nurses and other practitioners alike will find this handbook to be an essential resource for drug therapy in complex and high-risk patients with acquired and congenital heart disease.

Handbook of Pediatric Surgical Patient Care focuses on the decision-making process in the overall management of the pediatric surgical patient and provides guidelines for diagnosis. The book covers topics ranging from a wide spectrum of neonatal conditions and surgical critical care to other childhood afflictions, pediatric cancer and the injured child. It also focuses on the current management of common childhood conditions including appendicitis, pyloric stenosis and hernias. The purpose of this handbook is to provide a brief, easily accessible, rapid source of contemporary information to students, residents and practitioners caring for infants and children with surgical disorders.

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Biomedical and pharmacological
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information from the National Library of Medicine. Links are from
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or productsLPCH
CareNotes via MicroMedex: Patient education handouts customized by
LPCH clinical staffMicromedex
Lab Advisor: Evidence based laboratory test informationA drug database organized by generic
name, trade name and drug class.LPCH /
Stanford Hospital Formulary.A
goldmine of trusted consumer health information from the world's
largest medical library.A trusted
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Largest,
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In addition to covering Wiley and Springer, MyiLibrary is also
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Over 10,000 notes outline the status of specific infections
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Large number of high quality software
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