Contents

Purpose

The purpose of this week's lab is to compare and analyze the strengths and weaknesses of different scholarly search engines and using the references found to study the relationship between structure and function of the HIV virus.

Google Scholar Disadvantages-Can only sort by date and relevance and cannot tell if a source is a review or primary literature

PubMed Advantages-Extensive Filters/allows for specificity and Labels Reviews/easy to differentiate

PubMed Disadvantages- Limited access to free full-text journals and much more complicated when trying to use the filters and look for specifics

Web of Science Advantages-Tagged for the function i.e. review article and easy to re-find a paper, making it easy when doing research

Web of Science Disadvantages- Only searches the abstract and tagging information and need to have institution access

Number 15 Assignment

Keywords can vastly change your search results, for instance, all of us students chose different phrases to use to search when looking up the same topic and got vastly different numbers for search results.

Abstract Summary- In this study, the authors looked at vicriviroc, a coreceptor antagonist of CCR5 that is used in treatment for HIV-1. The results of the study should that the VCV-resistant virus modified itself to use the drug-bound receptor, increasing the reliance on the N-terminus of CCR5.

Journal Club Recommendation-No we should not use this article for journal club because of the article was not organized in a manner that was easy to follow along with.

Copy and Paste into class BIB

Conclusion

Before Week 8"s class the only search engine I used for a majority of my projects was google scholar unless I was told to do otherwise. Week 8's class taught me the shortcomings of google scholar and how I can use other search engines to narrow down my search and find the best possible paper for my projects. For instance, I did not know PubMed stated when a paper was a Review, which is very helpful information when a professor is asking for a primary literature article, with this tool you do not have to open the paper and check for each one if it is a review or not. A feature that I knew before this class but that was also mentioned in class was the fact that google scholar gives citations, which is very helpful when including references on a paper.