Fusion

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

XP_504416.1

YALI0E26235p (374 aa)

Predicted Functional Partners:

NPL4

YALI0E13233p; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity) (563 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

NPL4

XP_502686.1

XP_503893.2

XP_502686.1

YALI0E13233p; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity)

YALI0D11132p

0.866

NPL4

XP_502745.1

XP_503893.2

XP_502745.1

YALI0E13233p; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity)

YALI0D12452p

0.877

NPL4

XP_502773.1

XP_503893.2

XP_502773.1

YALI0E13233p; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity)

YALI0D13046p

0.886

NPL4

XP_502835.1

XP_503893.2

XP_502835.1

YALI0E13233p; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity)

YALI0D14784p

0.935

NPL4

XP_503636.1

XP_503893.2

XP_503636.1

YALI0E13233p; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity)

YALI0E06655p

0.965

NPL4

XP_504128.2

XP_503893.2

XP_504128.2

YALI0E13233p; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity)

YALI0E18986p

0.799

NPL4

XP_504416.1

XP_503893.2

XP_504416.1

YALI0E13233p; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity)

YALI0E26235p

0.998

NPL4

XP_505137.1

XP_503893.2

XP_505137.1

YALI0E13233p; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity)

YALI0F07843p

0.939

NPL4

XP_505319.1

XP_503893.2

XP_505319.1

YALI0E13233p; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity)

YALI0F12155p

0.997

XP_501290.1

XP_502745.1

XP_501290.1

XP_502745.1

YALI0C00561p

YALI0D12452p

0.686

XP_501290.1

XP_504128.2

XP_501290.1

XP_504128.2

YALI0C00561p

YALI0E18986p

0.956

XP_501290.1

XP_504416.1

XP_501290.1

XP_504416.1

YALI0C00561p

YALI0E26235p

0.920

XP_502686.1

NPL4

XP_502686.1

XP_503893.2

YALI0D11132p

YALI0E13233p; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity)

0.866

XP_502686.1

XP_502745.1

XP_502686.1

XP_502745.1

YALI0D11132p

YALI0D12452p

0.922

XP_502686.1

XP_502773.1

XP_502686.1

XP_502773.1

YALI0D11132p

YALI0D13046p

0.895

XP_502686.1

XP_502835.1

XP_502686.1

XP_502835.1

YALI0D11132p

YALI0D14784p

0.710

XP_502686.1

XP_503636.1

XP_502686.1

XP_503636.1

YALI0D11132p

YALI0E06655p

0.929

XP_502686.1

XP_504128.2

XP_502686.1

XP_504128.2

YALI0D11132p

YALI0E18986p

0.937

XP_502686.1

XP_504416.1

XP_502686.1

XP_504416.1

YALI0D11132p

YALI0E26235p

0.867

XP_502686.1

XP_505319.1

XP_502686.1

XP_505319.1

YALI0D11132p

YALI0F12155p

0.946

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: