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Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar. Best Paper Award : Dr. Muhammad Baqir MR Fakhrildin
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Abstract

Acute disseminated encephalomyelitis (ADEM) is an acute widespread
demyelinating condition, which principally affects brain and spinal
cord. It usually follows an infection or vaccination. The ADEM is a
monophasic disease characterized by multifocal white matter lesions
on neuroimaging. A case of post-vaccinial encephalitis after purified
chick-embryo cell anti-rabies vaccination is presented for its rarity. We
are reporting a case report of patient of 25 years old male presented
with paraplegia with bladder retention and diplopia with exaggerated
DTR and extensor plantar of acute onset with recent history of ARV
vaccination. Cerebrospinal fluid examinations shows raised proteins
and MRI imaging showed demyelinating lesions characteristic lesions
seen on MRI appear as patchy areas of increased signal intensity on
conventional T2-weighted images and on fluid attenuated inversion
recovery sequence (FLAIR) predominantly seen in bilateral
asymmetric parieral region, basal ganglion, thalamus, brain stem, cervical and thoracic
cord with patchy distribution and skip lesions of ADEM in light of clinical scenario. The
patient was treated with methylprednisonlone and responded well, diplopia, bladder
involvement and paraplegia recovered over ten days.