The next generation of protein interaction assays

“Next Interaction’s NGIS screening with mutant and wild-type version of a gene implicated in hearing disorders revealed distinct interactions that may underlie observed phenotypes. These initial findings were crucial to our current research.”Nicolas Grillet, Ph.D., Assistant Professor, Stanford University, USA

“With Next Interactions we were able to map candidate interactors to a novel protein epitope, allowing us to reach pivotal conclusions for our project. Great customer care and turnaround!”Gregor Andelfinger, MD, FRCPC, Université of Montréal, Canada

“Next Interactions is the ideal partner in molecular engineering and screening of synthetic proteins. This is an excellent team with such dedication, knowledge and enthusiasm.“Shuguang Zhang, Ph.D., Massachusetts Institute of Technology, USA

Protein-protein interactions fundamentally underlie the function of biological systems. Measuring protein-protein interactions is central to understanding the biological basis of disease and for enabling biotechnology to produce products ranging from safer and more effective therapeutics to next-generation foods, materials, and fuels.

Next Interactions, Inc. is a proteomics services company that delivers more complete, sensitive, and precise measurements of protein-protein interactions. We have developed a Next Generation Sequencing-Yeast Two Hybrid (NGS-Y2H) technology platform that combines the latest innovations in sequencing, yeast-based protein interaction mapping techniques, and quantitative cell-based reporters.

We offer a variety of protein interactome discovery solutions, including parallel interaction fingerprints, comparative interaction profiles, and complete screening of protein variants and mutational profiles of proteins, in addition to the construction and use of custom cDNA libraries for our clients.

Protein Interaction Screening Challenges

Understanding protein interactions can be powerful, but protein interaction screens need to be improved.

Quantitation

Precision

Data Visualization

Effective visualization is required to analyze quantitative and comprehensive results.

Consult our Protein Interaction Screening Experts.

Contact Next Interactions for advice from our scientists about the best approach for elucidating the protein interactions you need to understand for your research. We can advise you on methods such as the NGS-yeast two-hybrid system, yeast two-hybrid system, how to compliment interactome coverage by mass spectrometry, and more.