I would try Slic3r again but use 0.2mm for the first layer and support. If you are using the stock nozzle 0.4mm is too high of a layer height. I will typically not go more than 75% of the nozzle diameter.

In KISSlicer, are you using the profile that has the prime line at the beginning?

Agreed about following the directions exactly as written. I noticed the web interface loads quicker which is nice, but the main issue which I was hoping to solve was the AJAX disconnects and it doesn't appear to have solved that issue with 1.19. One not about 1.20 is it is still in early beta stages...

Awesome! I noticed the web interface is much quicker too. Only strange thing is deleting files, I read somewhere that you have to hover over the item and right click it to delete or something like that.