A field experiment was carried out to study the variety difference of growth response and Cd accumulation in 28 cultivars of sunflower (Helianthus annuus L.) in typical Cd-contaminated farmland soil with 2.22mg/kg Cd in Northern China, which aimed to screen sunflower cultivars with high accumulation of Cd. The results showed that significant differences were observed among 28 cultivars of sunflower, with the shoot biomasses ranged from 1 101.38kg/hm 2-12 511.13kg/hm 2, the shoot Cd concentrations ranged from 1.68mg/kg-19.25mg/kg, the bioconcentration factor ranged from 0.76-8.67, and the uptake amount of Cd ranged from 4.17g/hm 2-114.20g/hm 2.According to the cluster analysis of Cd concentration in sunflower, 28 cultivars of sunflower were divided into 3 categories in which the G3, G1, Y1, G8, G12, G4 and G6 cultivars were defined as high accumulation capacity cultivars. The analysis of Cd uptake in shoot of sunflower suggested that Y3, G24 and G3 cultivars could accumulated more than 100g/hm 2 Cd in shoot, which were suitable for applying in phytoremediation of Cd-contaminated soil.