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A discontinued drug is a drug that has been taken off the market due to safety issues, shortage of raw materials, or low market demand.

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Highlights for cilostazol

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1

CILOSTAZOL (sil OH sta zol) is used to treat the symptoms of intermittent claudication. This condition causes pain in the legs during walking, and goes away with rest. By improving blood flow, this medicine helps people with this condition walk longer distances without pain.

cilostazol Side Effects

Side effects that you should report to your doctor or health care professional as soon as possible:

allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

chest pain

fast, slow, or irregular heartbeat

signs and symptoms of bleeding such as bloody or black, tarry stools; red or dark-brown urine; spitting up blood or brown material that looks like coffee grounds; red spots on the skin; unusual bruising or bleeding from the eye, gums, or nose

swelling in the legs or ankles

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

diarrhea

headache

nausea, or upset stomach

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cilostazol May Interact with Other Medications

Oral tablet

Do not take this medicine with any of the following medications:

grapefruit juice

This medicine may also interact with the following medications:

agents that prevent or treat blood clots like enoxaparin or warfarin

aspirin

diltiazem

erythromycin or clarithromycin

omeprazole

some medications for treating depression like fluoxetine, fluvoxamine, nefazodone

some medications for treating fungal infections like ketoconazole, fluconazole, itraconazole

Disclaimer:
Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

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How to Use cilostazol

Oral tablet

Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 30 minutes before or 2 hours after food. Do not take with food. Take your doses at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of the following conditions:

bleeding disorder or hemophilia

history of heart failure, heart attack, or other heart disease

an unusual or allergic reaction to cilostazol, other medicines, foods, dyes, or preservatives

pregnant or trying to get pregnant

breast-feeding

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. It may take 2 to 4 weeks for your condition to start to get better once you begin taking this medicine. In some people, it can take as long as 3 months for the condition to get better.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.

Smoking may have effects on the circulation that may limit the benefits you receive from this medicine. You may wish to discuss how to stop smoking with your doctor or health care professional.

If you are going to have surgery, tell your doctor or health care professional that you are taking this medicine.

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Last Updated: April 10, 2014

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