A carboxylic ester resulting from the formal condensation of (<stereo>S</stereo>)-2-methylbutyric acid with the hydroxy group adjacent to the ring junction of (3<stereo>R</stereo>,5<stereo>R</stereo>)
-7-[(1<stereo>S</stereo>,2<stereo>S</stereo>,6<stereo>S</stereo>,8<stereo>S</stereo>,8a<stereo>R</stereo>)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid. De
rived from microbial transformation of mevastatin, pravastatin is a reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA). The sodium salt is used for lowering cholesterol and preven
ting cardiovascular disease. It is one of the lower potency statins, but has the advantage of fewer side effects compared with lovastatin and simvastatin. ChEBICHEBI:63618

Pravastatin is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 ?M.; Target: HMG-CoA reductase; Pravastatin (marketed as Pravachol or Selektine) is a member of the drug class of statins, used in combination with diet, exercise, and weight-loss for lowering cholesterol and preventing cardiovascular disease.; Pravastatin is primarily used for the treatment of dyslipidemia and the prevention of cardiovascular disease. MedChem ExpressHY-B0165