Rather than seeking a new partner after a worldwide licensing deal with Roche AG quietly terminated last year, privately held Chiasma Inc. decided to take its new drug application (NDA)-ready oral octreotide to market in the U.S. on its own. And new and existing investors stepped up to help, to the tune of $70 million.

Cellectis SA, which last month disclosed plans to file for an IPO of American Depositary Shares (ADS) on the U.S. markets, dropped its paperwork, indicating it will seek to raise up to $115 million, including overallotments, and a listing on the Nasdaq Global Market under the ticker CLLS. The Paris-based company trades on the Alternext market of the Euronext Paris under the symbol ALCLS.

DUBLIN  Funding continues to flow to European biotech, with Cardio3 Biosciences SA and Quantum Genomics SA raising €32 million (US$36 million) and €12.9 million (US$14.44 million), respectively, in secondary offerings last week. Both transactions confirm the current appetite among investors for European biotech, but a much sterner test of that support is on the near-term horizon, as a new Irish-American firm Malin Corp. plc unveiled ambitious plans to raise €275 million to €325 million in an IPO in Dublin shortly.

Malin is building a global portfolio of life sciences companies to which it will offer high-level operational expertise as well as capital. It has strong links with the former Elan organization, the long-time flagship of Ireland's life sciences sector, which Dublin-based Perrigo Co. plc acquired in 2013.

Former Elan CEO Kelly Martin and former chairman Bob Ingram are on its board. Its CEO is former