Browse our CrkL (CRKL) ELISA Kits

On www.antibodies-online.com are 22 V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) ELISA Kits from 11 different suppliers available. Additionally we are shipping CrkL Antibodies (190) and CrkL Proteins (11) and many more products for this protein. A total of 235 CrkL products are currently listed.

The impaired T-cell proliferation and reduction of CRKL, phosphorylated CRKL, and c-Fos levels suggest a possible role of CRKL in functional deficiencies of T cells in patients with pDGS.

he findings in this study indicate a regulation relationship between CRKL and SLC7A5 (show SLC7A5 ELISA Kits), and provide useful evidence for gastric cancer therapeutic strategies.

We identified a recurrent 370-kb deletion at the 22q11.2 locus as a driver of kidney defects in the DiGeorge syndrome and in sporadic congenital kidney and urinary tract anomalies. SNAP29 (show SNAP29 ELISA Kits), AIFM3 (show AIFM3 ELISA Kits), and CRKL appear to be critical to the phenotype, with haploinsufficiency of CRKL emerging as the main genetic driver.

a role for miR (show MLXIP ELISA Kits)-429 as a novel target suppressing invasion and migration of human cervical cancer cells through modulation of its targeting genes ZEB1 (show ZEB1 ELISA Kits) and CRKL, is reported.

both Crk and CrkL are required for the acquisition of cellular transformation by v-fos, whereas Crk plays a more prominent role than CrkL in v-ras-induced transformation.

The study screened CrkL binding proteins using RNA interference (RNAi) and identified Sorbs1 (show SORBS1 ELISA Kits) and Sorbs2 (show Sorbs2 ELISA Kits) as two proteins that are enriched at AChR clusters and are required for the formation of AChR aggregation in vitro.

CRKL plays an important role in hepatocarcinoma cell proliferation, invasion and migration as well hepatocarcinoma malignancy and metastasis.

CRKL is shown to act as a potential suppressor and to provide new insight for both the malignant behaviors of hepatocarcinoma cells and lymphatic metastasis mechanism of hepatocarcinoma.

The molecular signaling set off by ERalpha (show ESR1 ELISA Kits) and CrkL association may have a central role in pregnancy and cancer.

CrkL (CRKL) Antigen Profile

Antigen Summary

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.