On February 4, 1657, Oliver Cromwell, Lord Protector of England, issued the first residence permit to a Jew, Luis Carvajal, since the expulsion of all Jews from England by King Edward I in the year 1290. The edict of expulsion had been officially overturned in the previous year, 1656. The re-admittance of Jews into England was partially due to the efforts of the great scholar Rabbi Menasseh Ben Israel.

Rabbi Moshe Galante II was born in Safed in 1620 and later moved to Jerusalem where he founded a large yeshivah. He was a grandson of the famed Rabbi Moshe Galante I, who was a student of Rabbi Yosef Karo.

Rabbi Galante was the first rabbi endowed with the title Rishon l'Tzion ("the First of Zion"), a title traditionally conferred upon the Chief Sephardic Rabbi of Jerusalem and later of the Land of Israel. This due to the profound love and esteem he was given by the Sephardic community in Jerusalem.

He authored a number of works including Elef HaMagen, which includes 1,000 responsa on various topics; Parpara'ot l'Chochmah, a commentary on the Bible; and Zevach HaShelamim on the Talmud.

Counted among his students was Rabbi Chizkiyah De Silva, rabbi of Hebron and author of the Pri Chadash (printed in the standard edition of the Code of Jewish Law).