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Intensity inhomogeneity is the prime obstacle for MR image processing like automatic segmentation, registration etc. This complication has strong dependence on the associated acquisition hardware and patient anatomy which recommends retrospective correction. In this paper, a new method is developed for correcting the intensity inhomogeneity using a non-iterative multi-scale approach that doesn't necessitate...

The use of enteral feeding tubes to administer antiretroviral medications is necessary in certain patients with human immunodeficiency virus (HIV) infection. However, adequacy of drug exposures after these administration routes are largely unknown, making dosing recommendations and the attainment of viral suppression challenging in this patient population. This report describes a patient with advanced...

One of the most significant benefits of directional drilling is the increase in well productivity using multiple wells from a single vertical wellbore. During directional drilling, the drill pipe rests on the low-side of the annulus because of gravity. Moreover, cuttings beds form on the low-side of the annulus. Cuttings beds are undesirable because they increase hydraulic resistance of the annulus...

The reconstruction of the signal from hadrons and jets emerging from the proton–proton collisions at the Large Hadron Collider (LHC) and entering the ATLAS calorimeters is based on a three-dimensional topological clustering of individual calorimeter cell signals. The cluster formation follows cell signal-significance patterns generated by electromagnetic and hadronic showers. In this, the clustering...

Recent reports indicate that anthelmintic resistance in gastrointestinal nematodes of cattle is becoming increasingly prevalent worldwide. Presently, the fecal egg count reduction test (FECRT) is the only means available for detection of resistance to anthelmintics in cattle herds at the farm level. However, the FECRT is labor and cost intensive, and consequently is only rarely performed on cattle...

Cisco Coregonus artedi, a historically abundant and commercially important fish in the Great Lakes, have declined drastically in the last century due to the impacts of invasive species, overfishing, and habitat degradation. Chaumont Bay, New York is believed to contain one of the last remaining spawning populations of cisco in Lake Ontario although direct evidence of spawning has remained elusive...

Laminar plumes from a line source of warm water at the base of a shallow, homogeneous body of cold water (below the temperature of maximum density) were simulated by a computational model. The plume water undergoes buoyancy reversal as it mixes with the cold ambient. If this occurs before the plume has reached the ceiling of the domain, the plume flaps from side to side. Otherwise, it spreads along...

Vaccine exposure to temperatures below recommended ranges in the cold chain may decrease vaccine potency of freeze-sensitive vaccines leading to a loss of vaccine investments and potentially places children at risk of contracting vaccine preventable illnesses.This literature review is an update to one previously published in 2007 (Matthias et al., 2007), analyzing the prevalence of vaccine exposure...

Background District hospitals in sub-Saharan Africa are in need of investment if countries are going to progress towards universal health coverage, and meet the sustainable development goals and the Lancet Commission on Global Surgery time-bound targets for 2030. Previous studies have suggested that government hospitals are likely to be highly cost-effective and therefore worthy of investment. Methods...

Application of fluid shear stress to adherent cells dramatically influences their cytoskeletal makeup and differentially regulates their migratory phenotype. Because cytoskeletal rearrangements are necessary for cell motility and migration, preserving these adaptations under in vitro conditions and in the presence of fluid flow are physiologically essential. With this in mind, parallel plate flow...

Cervically implanted vagus nerve stimulation (VNS) is FDA-approved for treating epilepsy or major depression. Additionally, interest in VNS has reemerged, showing promise in several translatable animal studies. We have developed a noninvasive device that electrically stimulates the auricular branch of the vagus nerve called transcutaneous auricular vagus nerve stimulation (taVNS).The aims of this...

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