Summary

This phase II trial is studying how well decitabine works in treating patients with
metastatic papillary thyroid cancer or follicular thyroid cancer that has stopped responding
to radioactive iodine. Iodine I 131 (radioactive iodine) kills thyroid cancer cells.
Metastatic thyroid cancer cells can lose the ability to be treated with radioactive iodine.
Decitabine may help thyroid cancer cells regain the ability to respond to treatment with
radioactive iodine.