We hypothesized that the increase in mitochondrial proliferation in hearts from copper-deficient rats is due to an increase in expression of the transcriptional factor Ppargc1a, which regulates transcriptional activity for ...

Changes in mitochondrial and sarcoplasmic proteins using proteinomics and western blotting in hearts from copper deficient rats were explored in this study. Also, key enzymes that are involved in cardiac energy metabolism ...