ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

IP

1/30.

Target

Function

Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.

Sequence similarities

Belongs to the annexin family.Contains 4 annexin repeats.

Domain

A pair of annexin repeats may form one binding site for calcium and phospholipid.

The two band 37kDa is the full length band and the 33kDa supposed to be the cleavage form, this expression pattern observed is consistent with what has been described in the literature (PMID: 25510623 and 20679535).