THE SIMPSONS adventures continue this fall, beginning Sunday, Sept. 28, with a stellar array of guest voices, including Jane Fonda (“The Newsroom”), who is featured as Mr. Burns’ girlfriend, Democratic Assemblywoman Maxine Lombard; Willem Dafoe (“The Grand Budapest Hotel”) as Bart’s new bully-of-a-teacher, Mr. Lassen; and “Futurama’s” Billy West, John DiMaggio, Katey Sagal, Maurice LaMarche, Phil LaMarr, Lauren Tom and Tress MacNeille in a crossover episode between the two animated series. Additional 26th season guest voices include Nick Offerman (“Parks and Recreation”), Sarah Silverman (“A Million Ways to Die in the West”), David Hyde Pierce (“Frazier”), comedian Jeffrey Ross and musician Matthew Sweet. Plus, Judd Apatow (“Girls,” “Anchorman 2: The Legend Continues”) pens a special episode scheduled to air later in the season.

FAMILY GUY (Sundays, 9:00-9:30 PM)

In this season’s special one-hour premiere of FAMILY GUY, “The Simpsons Guy,” airing Sunday, Sept. 28 (9:00-10:00 PM), two of the most iconic and revered families on television will come together when the Griffins meet The Simpsons, with guest voices by Dan Castellaneta as Homer Simpson, Nancy Cartwright as Bart Simpson, Hank Azaria as Moe, Yeardley Smith as Lisa and Maggie and Julie Kavner as Marge. The rest of the star-studded season will include guest voices by Liam Neeson (“Taken 2”), Julie Bowen (“Modern Family”) and Allison Janney (“Mom”).

AMERICAN DAD (Sundays, 9:30-10:00 PM)

AMERICAN DAD wraps up its run on FOX with three all-new episodes this fall. First, in the special one-hour season premiere (Sunday, Sept. 14, 9:00-10:00 PM), Roger is forced to sell his beloved attic bar to a restaurant chain after suffering a heart attack, and a sexy new next-door neighbor (guest voice Jane Krakowski, “30 Rock”) promises to take Steve and his friends’ virginity in return for housework. John Lutz (“30 Rock”) and Eddie Kaye Thomas (“American Pie”) also guest-voice. In the final FOX episode (Sunday, Sept. 21, 9:30-10:00 PM), Roger and Francine discover an alien in the woods (guest voice Kim Kardashian), and Roger has a fling with her. Swoosie Kurtz (“Sisters”), Corey Stoll (“The Strain”) and Steven Yeun (“The Walking Dead”) also guest-voice.