A 1920 Italian wrought-iron ceiling fixture is suspended above a bronze sculpture by Libero Andreotti and a pair of ’30s armchairs in the entrance hall; the wall sculpture is a contemporary piece by Lucio Perone.

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The living room features a metal bar made by François-Xavier Lalanne for Yves Saint Laurent and Pierre Bergé. A white nail-studded Enrico Castellani painting hangs above the Rovatti-designed sofa, as do works by (from left) Lucio Fontana, Henri Matisse, and Alberto Burri.

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On one side of the living room, a pair of Lalanne bronzes—a desk in the form of a preening mountain sheep and a ram stool—flank a seating area; a Giorgio Morandi still life is mounted on an 18th-century Italian gilt-wood mirror, while Gio Ponti vases rest on nesting tables by Rovatti. The red-lacquer stool is by Émile-Jacques Ruhlmann.

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White leather sofas by Rovatti anchor the library.

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A Thonet chair by Josef Hoffmann accompanies a Rovatti table; the floor lamp is by Vibia.

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Armchairs by Patricia Urquiola for De Padova sit next to the fireplace; the drawing is by Pablo Picasso, and the bronze figures on the tables are by Umberto Baglioni.

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Canvases by Carlo Levi, Anthony Moore, Felice Casorati, and Alberto Ziveri are displayed near Rovatti-designed maple benches in the portrait gallery; the woman at center is Adele Fendi, the company’s founder and Carla’s mother.

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Fendi and Speroni share a moment near a painting by Giulio Aristide Sartorio.

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In the dining room, a painting by Mario Sironi overlooks a circa-1925 Murano-glass-and-paste tabletop decoration by Napoleone Martinuzzi that was owned by the Italian royal family.

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IKEA metal chairs are pulled up to a counter in the kitchen, which is paved with Sicis tiles.

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The billiard room’s 17th-century ceiling hosts a Rovatti pendant light; the Brenno del Giudice armoire is from the 1930s, as is the pool table.

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Joe Colombo card tables from 1968 furnish the bridge room, along with vintage Cassina hanging lights; the French bar and Spanish carpet are from the ’30s.

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The fashion executive’s bedroom is outfitted with a French Art Deco bed made of thuya wood; the chandelier is 19th-century French, and the nude is by Scuola Romana artist Francesco Trombadori.