Physiologically, the pressure that is primarily regulated is the mean arterial pressure. This is the average level of the blood pressure over several heart beats. This could be determined by measuring the blood pressure at many closely spaced intervals and averaging the numbers. But this is not necessary, since it can be estimated satisfactorily by adding one-third of the pulse pressure (see below) to the diastolic pressure.
Mean Arterial Pressure ~= 1/3 * SBP + 2/3 * DBPhttp://www.mdcalc.com/mean-arterial-pressure-maphttp://courses.washington.edu/conj/circulation/reflectedPulse.htm

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Dr. Johnson Francis

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Senior Consultant Interventional Cardiologist & Former Professor of Cardiology. Founder and Emeritus Editor of Indian Pacing and Electrophysiology Journal. Co-editor of: "Leo Schamroth - An Introduction to Electrocardiography", Eighth Adapted Edition. Peer Reviewer for 15 International Journals including The Journal of American College of Cardiology and Heart Rhythm. Published more than forty articles in reputed journals. International Editorial Board Member, Europace, the official Journal of European Heart Rhythm Association.

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