Browse our CSF2RB Proteins (CSF2RB)

On www.antibodies-online.com are 12 Colony Stimulating Factor 2 Receptor, Beta, Low-Affinity (Granulocyte-Macrophage) (CSF2RB) Proteins from 6 different suppliers available. Additionally we are shipping CSF2RB Antibodies (125) and CSF2RB Kits (20) and many more products for this protein. A total of 167 CSF2RB products are currently listed.

Exome sequencing identified candidate variants, including a missense mutation in DUOX2 (show DUOX2 Proteins) that impaired its function and a frameshift mutation in CSF2RB that was associated with Crohn's Disease in an independent cohort of Ashkenazi Jewish individuals.

In a genetic analysis of Ashkenazi Jewish individuals, we associated Crohn's Disease with a frameshift mutation in CSF2RB. Intestinal monocytes from carriers of this mutation had reduced responses to granulocyte-macrophage colony-stimulating factor (show CSF2 Proteins), providing an additional mechanism for alterations to the innate immune response in individuals with Crohn's Disease.

Suggest that beta common receptor may play an integrative role in the erythropoietin (show EPO Proteins) signaling-mediated activation of eNOS (show NOS3 Proteins) in endothelial cells.

CSF2RB Protein Profile

Protein Summary

The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP).