School of Medicine

Showing 1-20 of 37 Results

Current Research and Scholarly Interests
Our current research is focused on evaluation of cardiac bioenergetics and cardiac mechanics in pediatric sepsis. In particular, we have focused our efforts on the identification of developmental variability in cardiac bioenergetic reserve and mitochondrial oxidative stress in the setting of sepsis. Additionally we explore the role of mitochondrial dynamics in critical illness.

Bio
Jens Hainmueller is a Professor in the Department of Political Science at Stanford University and holds a courtesy appointment in the Stanford Graduate School of Business. He is also the Faculty Co-Director of the Stanford Immigration Policy Lab that is focused on the design and evaluation of immigration and integration policies and programs.

His research interests include immigration, statistical methods, political economy, and political behavior. He has published over 40 articles, many of them in top general science journals and top field journals in political science, statistics, economics, and business. He has also published three open source software packages and his research has received awards and funding from the Carnegie Corporation, the Russell Sage Foundation, the Robin Hood Foundation, the National Science Foundation, the Swiss SNF, the American Political Science Association, Schmidt Futures, the Society of Political Methodology, the National Bureau of Economic Research, and the Midwest Political Science Association.

Hainmueller received his PhD from Harvard University and also studied at the London School of Economics, Brown University, and the University of Tübingen. Before joining Stanford, he served on the faculty of the Massachusetts Institute of Technology.

Current Research and Scholarly Interests
1. development of hospital operations centers coupled with sophisticated simulation capabilities2. re-creation of near misses and adverse events 3. optimizing human and system performance during resuscitation 4. optimizing pattern recognition and situational awareness at the bedside5. evaluation and optimization of debriefing6. patient simulator design

Current Research and Scholarly Interests
My primary area of scholarly and clinical interest is the pathogenesis of problem behaviors shown by individuals diagnosed with intellectual and developmental disabilities (IDD), particularly those with neurogenetic forms of IDD, such as fragile X syndrome, Cornelia de Lange syndrome and Prader-Willi syndrome. My work aims to both advance understanding of these disorders and to identify effective new treatment approaches for pediatric and adult patient populations by state-of-the-art methodologies, such as brain imaging, eye tracking and functional analysis to determine how environmental and biological factors affect the development of aberrant behaviors in these syndromes. The end goal of my research is to create patient-specific methods for treating the symptoms of these disorders.

Current Research and Scholarly Interests
Principal InvestigatorInfrastructure to facilitate discovery of autism genesThe purpose of this project is to facilitate the discovery of the genes that contribute autism by maintaining an infrastructure which research groups studying the genetics of autism can work collaboratively. This will be accomplished through workshops, a Virtual Private Network, and access to a database that includes phenotype and genotype data from all participating groups.

Principal InvestigatorA California Population-Based Twin Study of AutismThis will address several fundamental questions: (1) What is the heritability of autism (2) What is the contribution of genetic factors to variation in symptom dimensions? (3) Is there a continuum between the quantitative neurocognitive traits and clinical disorder? (4) What proportion of the variance in the neurocognitive traits is accounted for by genetic and non-genetic factors?

Co-InvestigatorCenter for Integrating Ethics in Genetics Research(Cho)The goal of this project is to serve as a center of excellence in neurogenetics research, to develop a national model for bench, to bedside research ethics consultation, and to provide training opportunity in biomedical ethics.

Co-InvestigatorGene, Brain and Behavior in Turner Syndrome(Reiss)The primary objective of this project is to use advanced, multi-modal magnetic resonance imaging (MRI) techniques, analyses of X chromosome parent-of-origin and cognitive-behavioral assessment to elucidate the effects of monosomy and X-linked imprinting on neurodevelopment and neural function in a large cohort of young girls with Turner syndrome, pre-estrogen replacement.

Project DirectorProject F: Genomic Analysis in narcolepsy cataplexyThe goal of the project is to locate genes outside the HLA region that influence susceptibility to narcolepsy. In order to localize these genes we will carry out a linkage and association study in the most extensive world-wide collection of DNAs from well-characterized patients with narcolepsy and their families.

Current Research and Scholarly Interests
Research focuses on developmental, cognitive and psychosocial factors involved in adolescents? and young adults? health-related decision-making, perceptions of risk and vulnerability, health communication and risk behavior. My research has focused on understanding and reducing health risk behaviors such as tobacco use, alcohol and marijuana use, risky driving, and risky sexual behavior.

Current Research and Scholarly Interests
Dr. Hammer's primary research interests are pediatric pharmacology and perioperative care of children undergoing cardiac surgery. He has numerous funded research projects in these areas, including an NIH grant for $4.3 million to study the pharmacology of sodium nitroprusside, a drug commonly used for blood pressure control in the operating room and ICU. Dr. Hammer has two other NIH grants and other ongoing research projects in the area of pediatric pharmacology.

Current Research and Scholarly Interests
His research and clinical work focuses on the development of interventional techniques for fetal and neonatal treatment of congenital heart disease, pulmonary, vascular physiology, and the neurologic impact of open-heart surgery. He developed and pioneered the “unifocalization” procedure, in which a single procedure is used to repair a complex and life-threatening congenital heart defect rather than several staged open-heart surgeries as performed by other surgeons.

Current Research and Scholarly Interests
A bad latch means maternal excruciating pain, ineffective milk transfer with subsequent weight loss, hypoglycemia, higher risk of hyperbilirubinemia and dehydration fever.All of the above led to early cessation of breastfeeding; 46% of mothers who initiate exclusive breastfeeding stop within the first 12 weeks because of difficult latch. I developed a latch tutorial focusing on step-by step-in striations for achieving an effective, non-painful latch.

Current Research and Scholarly Interests
The neurobiology of autismNeuroimaging in individuals with autismPsychopharmacological treatment of children and adults with autism and/or developmental disordersThe neurobiology and innovative interventions of several neurogenic disorders including DiGeorge Syndrome (Velocardiofacial syndrome; 22q11.2 mutations), PTEN mutations, and Phelan McDermid Syndrome (22q13 mutations).

Current Research and Scholarly Interests
Our laboratory studies the mechanisms by which highly complex behaviors are mediated at the neuronal level, mainly focusing on the example of dynamic social interactions and the neural circuits that drive them. From dyadic interactions to group dynamics and collective decision making, the lab seeks a mechanistic understanding for the fundamental building blocks of societies, such as cooperation, empathy, fairness and reciprocity.

Current Research and Scholarly Interests
Flexible statistical modeling for prediction and representation of data arising in biology, medicine, science or industry. Statistical and machine learning tools have gained importance over the years. Part of Hastie's work has been to bridge the gap between traditional statistical methodology and the achievements made in machine learning.

Bio
I am a brain tumor neurosurgeon, treating patients with malignant and benign tumors, including glioma, brain metastases, meningioma, vestibular schwannoma, and pituitary adenomas. Our lab seeks greater understanding of the genetic and epigenetic mechanisms driving tumorigenesis and disease progression in malignant brain tumors. We currently study the capacity of cellular and cell-free nucleic acids to inform cancer biology and response to therapy. We also use single cell and cell subtype-specific transcriptomics to identify and target infiltrating glioblastoma. We use these techniques to identify mechanisms of tumor migration, and to stop tumor growth. Our laboratory is a unique and collaborative working environment, engaged in a dynamic research environment at Stanford. Our laboratory space lies at the heart of the Stanford campus between the core campus and the medical facilities, emblematic of the translational aspects of our work.

Current Research and Scholarly Interests
Our research focuses on the inner ear, from its earliest manifestation as one of the cranial placodes until it has developed into a mature and functioning organ. We are interested how the sensory epithelia of the inner ear that harbor the sensory hair cells develop, how the cells mature, and how these epithelia respond to toxic insults. The overarching goal of this research is to find was to regenerate lost sensory hair cells in mammals.

Bio
Lynn Hildemann's current research areas include the sources and dispersion of indoor aerosols, the physicochemical properties of organic aerosols, and assessment of human exposure to PM.

Prof. Hildemann received BS, MS, and PhD degrees in environmental engineering science from the California Institute of Technology. She is an author on >90 peer-reviewed publications, including two with over 1000 citations each, and another 6 with over 500 citations each. She has been honored with Young Investigator Awards from NSF and ONR, the Kenneth T. Whitby Award from the AAAR (1998), and Stanford's Gores Award for Teaching Excellence (2013); she also was a co-recipient of Atmospheric Environment?s Haagen-Smit Outstanding Paper Award (2001).

She has served on advisory committees for the Bay Area Air Quality Management District and for the California Air Resources Board. She has been an Associate Editor for Environmental Science & Technology, and Aerosol Science and Technology, and has served on the advisory board for the journal Environmental Science & Technology.

At Stanford, Prof. Hildemann is currently chair of the Department of Civil & Environmental Engineering. She has served as an elected member of the Faculty Senate, and chaired the School of Engineering Library Committee, the University Committee on Judicial Affairs, and the University Breadth Governance Board..