An investigation of the transition to delta matter is performed based on a relativistic mean field formulation of the nonlinear sigma and omega model. We demonstrate that in addition to the Delta-meson coupling, the occurrence of the baryon resonance isomer also depends on the nucleon-meson coupling. Our results show that for the favored phenomenological value of m* and K, the Delta isomer exists at baryon density ~ 2–3 p0 if beta=1.31 is adopted. For universal coupling of the nucleon and Delta, the Delta density at baryon density ~ 2–3 p0 and temperature ~ 0.4–0.5 fm-1 is about normal nuclear matter density, which is in accord with a recent experimental finding.