CASTLE

Cas·tle

CASTLE

CardiologyCandesartan Amlodipine Study of Tolerability and Efficacy.

PathologyCarcinoma showing thymus-like elements. An acronym for a rare indolent tumour that occurs in middle-aged adults. CASTLE is similar to thymic carcinoma of the lymphoepithelioma or squamous cell variety, and thought to arise either from ectopic thymus or remnants of branchial pouches that retain the potential to differentiate along the thymic lines.

SitesAnterior mediastinum, soft tissues of the neck and thyroid; it ranges from completely benign to malignant.

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