Diagnosis and management of premenstrual disorders

In the “Psychotropic drugs” section of this clinical review by Shaughn O’Brien and colleagues (BMJ 2011;342:d2994, doi:10.1136/bmj.d2994) the authors state that selective serotonin reuptake inhibitors have not been shown to be teratogenic. This is wrong; they have been. The reference quoted in support of the authors’ erroneous statement actually reads: “Paroxetine has been associated with significant risks of major malformation, particularly cardiac defects, when used during pregnancy.”