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A normal girl from a small town, graduated from a super sophisticated uni and working in a luxurious city... Loves writing, loves reading, loves shopping, loves talking, loves MUSIC,MATHS and MEDICINE.

Wishing star

:: Christ-like life
:: Happy family
:: Be a good Doctor
:: Be a good Wife
:: Be a good Daughter
:: Be a good Daughter-in-Law
:: Be a good Mother
:: High IQ
:: High EQ
:: Lots of $$$$
:: Lots of good friends
:: Become Prettier
:: Become Thinner
:: More Talented
:: Healthy parents

Followers

I decided to make a comparison between all the various whitening pills esp in the aspect of ingredients.

As I am taking Lucent currently to try up the effectiveness.......

My 2 boxes of Lucent. Got it from a registered clinic in KL. Don't get cheated by the photo, the boxes are cute and tiny actually.

Both Lucent and Crystal Tomato boxes side by side.

According to the claimed by Lucent and EstheWhite, the PhytoflORAL tomato powder is the 3rd generation of Crystal Tomato carotenoid powder, which means their ingredient is much potent even though in a lower dosage.

This the TABLE i make for all few types of whitening pills available in Malaysia 's Clinic. All these medication are marketed through registered clinic. So if you got from unknown seller / online / non clinic centre, kindly question the source.

The ingredient in Crystal Tomato

The ingredient in Lucent

I had never took EstheWhite before and can't find a photo with the actual ingredient of that product. If I have chance to try in future i will upload here k.

Here's the comparison for those Japanese brand whitening product, most of the product contains high dose of Vitamin C and L-Cysteine - at least double the dosage! However actually i do read from somewhere that L-Cysteine is actually of no use in whitening effect.

CHOCOLA
BB Lucent C

The ingredients in Japanese

TRANSINO White C

The ingredients in Japanese

FANCL White Force

The down side of those Japanese brand whitening pill is that, you need to consume many tablets for the optimal effect.

For me, I think as long as the product is safe and able to deliver optimal result, with supplement in the product, then it's safe to take for long term. Another thing to consider is the price, for me Lucent's price range still acceptable. Hope can see a good result by then.

○ Relief of the following symptoms: Spots, freckles and pigmentation due to sun exposure or rash

○ Bleeding prophylaxis in the following situations: Gingival bleeding and epistaxis

○ Supply of Vitamin C in the following situations: Physical fatigue, pregnancy/lactation period, decline of physical strength during or after illness, and old age

Take the following amount with cold or warm water.

Age Adults (15 years or over)

Daily dose 3 tablets Twice a day in the morning and evening.

(1) Follow the Dosage and Administration strictly. (2) Use for children aged 7 or over should be supervised by guardians.

This product is a slightly orangish white to white film-coated tablet.

Taking this product may affect the results of laboratory tests performed on the urine or feces. If you are examined by doctors, tell them that you are taking a medicine containing Vitamin C. (2) The riboflavin (vitamin B2) contained in this product may turn the urine yellow.

The CHOCOLA BB series is designed to provide support for women's beauty and wellness through a number of products, such as CHOCOLA BB PLUS® for treating acne and other skin troubles. The new CHOCOLA® BB Lucent C helps whiten blemishes and brown spots on skin, two of the most common skin problems for women, and the introduction of the product will enable Eisai to respond to more diversified needs related to skin care.

It is widely believed that the oxidation in pigment cells of skin (melanocytes) causes excessive melanin production, which induces blemishes and brown spots on skin.

CHOCOLA® BB Lucent C , a pharmaceutical product which contains 600mg of vitamin C and 240mg of L-Cysteine in an adult daily dosage (6 tablets per day) promotes whitening of black-melanine with a redox action.

Containing a large quantity of L-Cysteine compared with other L-Cysteine consumer products, the CHOCOLA® BB Lucent C treats blemishes and brown spots at subepidermal level.

Also, natural type vitamin E, vitamin B2 and B6 have been added to improve blood flow in the epidermis and normalize skin metabolism (turnover), and eventually restore healthy skin.

Alleviation of the following conditions: blemishes and brown spots on skin, pigmentation caused by sunburn or rush

Vitamin C supplementation in the following conditions: physical fatigue, pregnancy and nursing, recuperation during and after sickness, aging

Prevention of bleeding from the gums and nose

Dosage and administration

Tablets should be taken with cold or hot water.
For an adult (15 years old and above), take 2 tablets, three times a day, before or after meals. For a child between 7 years old and 14 years old, take 1 tablet, three times a day, before or after meals.

When compared to the Chocola BB Plus’ main compound is Vitamin B2, Chocola BB Lucent C is a pharmaceutical product that has Vitamin C and L-cysteine as the main compounds. It softens the pigmentation resulting from freckles, spots, sunburn etc.

Chocola BB Lucent C works from inside our bodies to tackle existing skin spots or the root causes of spots, thus is recommended for anyone who wants to wants a brighten tone for their skin.Disclaimer: Most of the product information from the product website.

Carotenoids are natural sun protectants
found in plants. They absorb harmful UVA and UVB rays and supress free radicals
that lead to premature ageing and dark, uneven skin tone. The human body is
unable to produce carotenoids, but they can be obtained through diet.

EstheWhite’s key active ingredient,
PhytoflORAL® is a patented innovative dietary supplement derived from a
proprietary source of non-GMO tomato species that are rich in colourless
carotenoids – phytoene and phytofluene. These specific carotenoids are known to
lighten and even out skin tone through

It has been shown to prevent the
production of darker melanin, stimulate the production of glutathione, promote
skin renewal and display anti-oxidant effects

In a clinical study on the effects of
colorless carotenoids, clinical scoring by the dermatologist had shown that 60%
to 86% of the subjects’ skin quality was signiﬁcantly improved after 6 weeks
and up to 90% of the subjects had improvement in skin dryness, roughness,
suppleness, evenness and texture after 12 weeks. The research also showed that
after 12 weeks of colorless carotenoids intake, 65% of the subjects‘ skin had a
signiﬁcant 20% increase in the Minimum Erythemal Dose (MED) after UV exposure
testing, characterizing a photo-protective effect.

Is It Safe To Take EstheWhite?
EstheWhite is a natural food supplement, that consists of 100% non-GMO,
chemically unmodiﬁed tomato powder and natural amino acids. There are no known
safety concerns, however patients who are allergic or possibly allergic to
tomatoes should not take it without consulting their doctor. Pregnant and
breastfeeding patients are advised to consult with their obstetricians prior to
commencing.

The core ingredient of EstheShield is a
proven natural fern extract, polypodium leucotomos. It is an effective
chemophoto-protective agent that leads to a significant decrease of UV-induced
erythema, sunburn cell formation, DNA damage, epidermal hyperproliferation, and
dermal mast cell infiltration.

Polypodium leucotomos has been extensively
researched. Clinical studies show that polypodium extracts is effective in
defending skin against damage from UV radiation when taken orally. EstheShield
is a high potency formulation (500 mg) designed to provide the highest level of
protection.
Polypodium leucotomos has both antioxidant and anti-inflammatory properties
that help to prevent skin inflammation by inhibiting free radicals in skin
tissues from causing long-term DNA damage and photo-ageing.

Is It Safe To Take EstheShield?

EstheShield has been researched for over
40 years, with an excellent safety profile. There are no known
contraindications to polypodium leucotomos, however pregnant and breastfeeding
patients are advised to consult with their obstetricians prior to commencing.

Sun damage may not be visible at an
early age, but multiple studies warn of the consequences later in life. Sun
exposure damages fibres in the skin called elastin, resulting in skin laxity.
UV rays alter the DNA, causing saggy skin, lines, wrinkles, discolouration, age
spots, and even cancer.

UV radiation is composed of two
different wavelengths, UVA and UVB. When the skin is exposed to UV rays,
melanin is photo-oxidised (immediate pigment darkening). This is the process
that darkens your skin as it attempts to block out the radiation. Prolonged or
repeated exposure to UV radiation results in persistent pigment darkening and
eventually long term tanning (delayed tanning) which increases both the amount
and activity of melanocytes. The delayed tanning process can last 10 days to
several weeks, and with repeated exposure can cause DNA photo-damage.

UVB rays cause sunburn, but it is the
UVA rays, with their longer wavelength that penetrate deep into the dermis,
that are responsible for photo-ageing of skin. Sensitivity to sunburn is
routinely evaluated by minimal erythema dose (MED). MED describes the lowest
dose (J/cm2) of UV radiation that will cause erythema assessed 24 hours after
exposure. Higher MED means higher tanning capacity. Darker skin is a result of
increased number of melanin: it acts a barrier to the UV radiation.

PhytoflORAL

Carotenoids are natural sun protectants
found in plants. They absorb harmful UVA and UVB rays and suppress free
radicals that lead to premature ageing and dark, uneven skin tone. The human
body is unable to produce carotenoids, but they can be obtained through diet.

It has been shown to prevent the
production of darker melanin, stimulate the production of glutathione, promote
skin renewal and display anti-oxidant effects.

Clinical scoring of the skin quality was
significantly improved in 60 to 86% of the panelists after 42 days and in
up to 90% of the panelists after 84 days , across all parameters
evaluated. Of particular interest, 95% of the subjects had improved skin
evenness.

Study
subjects found their skin more resistant to sun damage, more beautiful and
visibly younger and healthier

Sunlight is a source for
external/topical generation of hydroxyl radicals, as was demonstrated by Taira
J. et al. This group suggested that sunlight exposure of skin may lead to
hydroxyl radical generation and simultaneous lipid peroxidation. Phytoene and
phytofluene, the colorless carotenoids are one of the few anti-oxidants that
are most effective in quenching of hydroxyl radicals (·OH) and shown in a
number of publications.

Polypodium leucotomos has been
extensively researched. Clinical studies show that polypodium extract is
effective in defending skin against damage from UV radiation when taken orally.
EstheShield is a high potency formulation (500 mg) designed to provide the
highest level of protection.

Polypodium leucotomos has both
antioxidant and anti-inflammatory properties that help to prevent skin
inflammation by inhibiting free radicals in skin tissues from causing long-term
DNA damage and photo-ageing.

Overall, 19 human and 6 basic science
studies were included in this review spanning over 40 years of research from
1972 to 2014. Oral polypodium leucotomos was administered in daily doses
ranging from 120 mg to 1080 mg. This review of literature has demonstrated that
PLE is well tolerated at all doses administered.

Current level of evidence suggests that
oral PLE is safe and can be prescribed confidently for long term use.

Much of the research that has been done
on polypodium leucotomos over the past 40+ years has been on its management of
skin conditions and its photo-protective properties after it is ingested. Many
of these clinical studies have shown extracts of polypodium leucotomos to be
surprisingly effective at defending skin against damage from the sun
(ultraviolet radiation) when polypodium leucotomos is taken orally, with some
authors even calling it an “internal sunscreen.”

A 2010 publication reported the results
of a clinical trial in which 10 healthy volunteers were given either 240mg oral
polypodium leucotomos 8 hours and again 2 hours before UVA exposure, or not
given anything at all before UVA exposure. Prior to exposure, each individual
was measured to determine his or her baseline skin histology and how much UVA
radiation it took to cause erythema (MED: minimal erythema dose). After
exposure, skin samples were again taken and tested for CD (common deletion: a
type of DNA damage and a marker of chronic UVA radiation). At 2 times the MED
the non-PL group had increases of CD of 217% over baseline, while the group
taking PL had decreases of 84%. At 3 times the MED, the non-PL group had
increases of CD of 760% over baseline, while the group taking PL only had a 61%
increase on average. These trends were determined “very strong” by the
researchers, and while the data was not statistically significant (due in part
to the small sample size), the researchers concluded that Polypodium leucotomos
“may prevent UVA-induced skin photodamage possibly by preventing UVA-dependent
mitochondrial DNA damage.”

In 2007, a study found that polypodium
leucotomos extract was beneficial to individuals who are extremely sensitivity
to the sun. The individuals all had either polymorphic light eruption (itchy
red rashes from sun exposure) or solar urticaria (a form of hives caused by
sunlight), but had not responded well to other available therapies. These
patients’ response to sunlight was measured both before and after taking an
oral dose of 480 mg of Polypodium leucotomos. The researchers reported
that after taking Polypodium leucotomos and being exposed to sunlight, patients
had a relevant and statistically significant reduction of skin reactions and
subjective symptoms as compared to exposure without PL. The researchers
concluded that the “photoprotective activity of Polypodium leucotomos was
significant,” and furthermore, the tolerance of PL was excellent and
administration was shown to be effective and safe.

L-Cysteine

Glutathione, the major intracellular
reductant, may become rate limiting to cytotoxic lymphocyte activation and
proliferation under these circumstances. N-Acetylcysteine (NAC-cys) was used to
increase intracellular glutathione levels significant changes in total
glutathione (58% increase) at 96 hours.

Glutathione acts as a nucleophilic
scavenger and as an enzyme-catalyzed antioxidant in the event of
electrophilic/oxidative tissue injury. Therefore, glutathione has a major role
as a protector of biological structures and functions.

Reactive oxygen species (ROS) are
involved in various cellular events including cell proliferation, apoptosis and
immune responses L-cysteine is converted to intracellular
gluthathione acting as a scavenger of ROS.