Building up the blood-brain barrier

Article Abstract:

The diseases like strokes, brain tumors, traumatic injury or multiple sclerosis, which lead to blocking of the central nervous system, are accompanied by dysfunction of the (BBB). The Src-suppressed C kinase substrate SSeCKS, the main factor that triggers signaling of the cascades that keep the blood-brain-barrier(BBB) function is identified.

The effects of blood-brain-barrier(BBB) and src-suppressed C-kinase (SSeCKS) on the that lead to brain disorders like Alzheimer and Ischemic are illustrated. The Modulation of both brain angiogenesis and tight junction formation is regulated by SSeCKS by differentiation of BBB.