Ethnobotanical knowledge associated with wetland plants in Uasin Gishu County, Kenya, was assessed and documented. Data on the uses of plants, their local names, and parts used were collected through semi-structured interviews. Fifty wild plant species distributed across 45 genera and 23 families were cited as having traditional uses in the area. Of these, 26 were used as fodder, 14 as medicine, 12 as firewood, 9 as food, and 11 for construction. Some, like Cyperus papyrus L. and Acacia seyal Delile, had multiple uses. Thirty-one plants (62%) of the total recorded were herbs, 13 (26%) shrubs, 3 (6%) trees, and 3 (6%) climbers. Various plant parts were used for different purposes. Medicinal plants were useful in treating a total of 19 ailments and had various methods of preparation.