Examples:

In Dragon Ball Z, Buu tries to absorb Vegetto, but the absorbtion fails and Vegetto (now split into Vegeta and Goku) releases all the victims Buu had absorbed previously.

The Supreme Kais weakened Kid Buu into Buff Buu and finally Fat Buu when he tried absorbing them. It seems inconsistent considering how high their power-levels are, but its explained that because they are pure good, and Buu pure evil, the two forces diffused each other.

YuYu Hakusho: When Sensui Seven member Gourmet eats Elder Toguro to get his powers, Elder Toguro ends up taking over his body later.

Naruto: when Orochimaru tried to steal Sasuke's body, Sasuke reversed the process and absorbed him instead

Also, there's always the threat that the Tailed Beasts can take control of their hosts and go on a rampage. But a strong enough host can instead summon their power at will, and an even better host can make friends with their beast.

Toward the very end of Full Metal Alchemist Brotherhood, the Big Bad Father absorbs his Anti-Hero homunculus Greed, and his Ultimate Shield power with it. Having been previously defeated by Edward Elric, who figured out his extreme defensive abilities are merely carbon-based, Greed decides to turn his powers the other direction and turn Father's body into pathetic frail graphite...allowing the heroes to K.O. Father for good.

Previously, after Pride absorbs Kimblee, he is finally defeated by Ed Elric due to Kimblee weakening him from the inside.

Logan's Run: the computer was trying to drain his memories or something to find the hidden lair of the resistance groups. Instead, not only was there no "resistance", but the experiences outside the dome actually overloaded the system (c'mon it was a a rather short movie, they didn't spend that long outside).

In The Matrix, Agent Smith assimilates The Oracle, which appears to backfire in some way (since she knew he was coming). At the end, Neo defeats him by letting himself be assimilated. This gives Smith a direct link back to the machines, allowing them to purge the rogue AI.

In Ghost Rider, Blackheart No Sells Blaze's penance stare power the first time it's used on him since he doesn't have a soul. When he draws the trapped souls of San Venganza into his body in a bid to increase his power, Blaze realizes that he's made himself vulnerable to the stare and uses it to destroy him.

In Wreck-It Ralph, one of the main villains are Cybugs, which take on the features of whatever they eat. A Cybug eats King Kandy, who is assimilated a little too well and becomes said Cybug's primary consciousness.

Fanfics

In a Star Trek / Doctor Who / My Little Pony crossover fanfic "My Little Enterprise", the Doctor resolved the whole plot by going back in time to the destruction of his homeworld and impersonating the leader, tricking the Borg Celestia into having him assimilated, which allowed him to disrupt her during the final confrontation.

In the Discworld novel Carpe Jugulum, the Magpyrs suck Granny Weatherwax's blood and attempt to turn her. She survives the experience without becoming a vampire; the Magpyrs aren't so lucky, however, as feeding on Granny Weatherwax has allowed her to turn them. By the end, they're craving tea instead of blood and even talking like her.

In the Christmas special The Next Doctor, the cybermen attempt to upgrade Miss Hartigan, but she's so strong-willed that she not only survives the process with her mind intact but manages to rewrite the cybermen's programming.

In the Daleks Take Manhatten two-parter, in an experiment designed to save the Daleks from extinction, Dalek Sec absorbs human DNA and mutates itself into a human/dalek hybrid. The new hybrid-Sec finds himself developing human values and emotions, which eventually causes the other Daleks to execute him in disgust.

In Neverwinter Nights 2, if One of Many is in your party when you meet the dead god Myrkul, they'll ask you if they can eat Myrkul. Given that unlike your own Spirit-Eater curse, One of Many adds consumed souls to its collective, Myrkul will take over, resulting in a Bonus Boss.

The Borg Expy in an early Sluggy Freelancestrip run into this problem after assimilating Riff and Torg. "Since you have come among us, all we have done is drink fermented hopps beverages and ogle scantly clad females. This has seriously jeopardized our goal of the all-collective. We've never had to do this before... We are kicking you out."

In the 'Neogenic Nightmare' arc of Spiderman The Animated Series, Spiderman is attacked by the Vulture, a villain who uses advanced technology to steal vitality from others. Unfortunately for the Vulture, the mutation that gives Spiderman his powers is particularly unstable at the time of the attack, and he absorbs some of Spiderman's DNA, causing him to mutate in a monstrous man/spider hybrid.

Superman villain Parasite is a power stealer who also gains their weaknesses. This means whenever he steals Superman's powerset, Superman can actually beat him by using kryptonite.

One episode of South Park has Cartman's super high-tech Trapper Keeper begin assimilating all technology (beginning with a calculator, then a computer, then a lamp, then Cartman). "Trapper Keeper ready to ensorb." Eventually it goes on a rampage and heads for Cheyenne Mountain to ensorb the NORAD command center located there, but on the way it eats Rosie O'Donnell, weakening it enough for Kyle to turn it off.

In the last episode of The Secret Saturdays, V.V Argost has assimilated the Kur powers from Zak's Evil Twin from an anti-matter Mirror Universe, and then does the same to Zak himself to become even more powerful. But what Argost didn't realize (but Zak did) was what happens when matter and anti-matter combine, and Argost obliterates himself instead.

Young Justice had an appearance of Parasite who was defeated when he stole Miss Martian's powers without realizing they came with a weakness to fire, which the heroes exploit.

In The Matrix, Agent Smith assimilates The Oracle, which appears to backfire in some way (since she knew he was coming). At the end, Neo defeats him by letting himself be assimilated. This gives Smith a direct link back to the machines, allowing them to purge the rogue AI.

Would this include villains who steal powers and end up weakened by their side effects?

In Neverwinter Nights 2, if One of Many is in your party when you meet the dead god Myrkul, they'll ask you if they can eat Myrkul. Given that unlike your own Spirit-Eater curse, One of Many adds consumed souls to its collective, Myrkul will take over, resulting in a Bonus Boss.

EDIT: Note to self: plural possessive means put the apostrope after the 's'.

Toward the very end of Full Metal Alchemist Brotherhood, the Big Bad Father absorbs his Anti Hero homunculus Greed, and his Ultimate Shield power with it. Having been previously defeated by Edward Elric, who figured out his extreme defensive abilities are merely carbon-based, Greed decides to turn his powers the other direction and turn Father's body into pathetic frail graphite...allowing the heroes to K.O. Father for good.

In Ghost Rider, Blackheart No Sells Blaze's penance stare power the first time it's used on him since he doesn't have a soul. When he draws the trapped souls of San Venganza into his body in a bid to increase his power, Blaze realises that he's made himself vulnerable to the stare and uses it to destroy him.

The Aladdin example isn't this trope. However, I'd like to be the third to recommend the Carpe Jugulum example.

In the Discworld novel Carpe Jugulum, the Magpyrs suck Granny Weatherwax's blood and attempt to turn her. She survives the experience without becoming a vampire; the Magpyrs aren't so lucky, however, as feeding on Granny Weatherwax has allowed her to turn them. By the end, they're craving tea instead of blood and even talking like her.

In the 'Neogenic Nightmare' arc of Spiderman The Animated Series, Spiderman is attacked by the Vulture, a villain who uses advanced technology to steal vitality from others. Unfortunately for the Vulture, the mutation that gives Spiderman his powers is particularly unstable at the time of the attack, and he absorbs some of Spiderman's DNA, causing him to mutate in a monstrous man/spider hybrid.

The Borg Expy in an early Sluggy Freelancestrip run into this problem after assimilating Riff and Torg. "Since you have come among us, all we have done is drink fermented hopps beverages and ogle scantly clad females. This has seriously jeopardized our goal of the all-collective. We've never had to do this before... We are kicking you out."

In the Christmas special The Next Doctor, the cybermen attempt to upgrade Miss Hartigan, but she's so strong-willed that she not only survives the process with her mind intact but manages to rewrite the cybermen's programming.

In the Daleks Take Manhatten two-parter, in an experiment designed to save the Daleks from extinction, Dalek Sec absorbs human DNA and mutates itself into a human/dalek hybrid. The new hybrid-Sec finds himself developing human values and emotions, which eventually causes the other Daleks to execute him in disgust.

In a Star Trek / Doctor Who / My Little Pony crossover fanfic, the Doctor resolved the whole plot by going back in time to the destruction of his homeworld and impersonating the leader, tricking the Borg Celestia into having him assimilated, which allowed him to disrupt her during the final confrontation.

In Wreck It Ralph, one of the main villains are Cybugs, which take on the features of whatever they eat. A Cybug eats King Kandy, who is assimilated a little too well and becomes said Cybug's primary consciousness.

The Supreme Kais weakened Kid Buu into Buff Buu and finally Fat Buu when he tried absorbing them. It seems inconsistent considering how high their power-levels are, but its explained that because they are pure good, and Buu pure evil, the two forces diffused each other.

Naruto When Orochimaru tried to steal Sasukes body, Sasuke reversed the process and absorbed him instead

Also theres always the threat that the Tailed Beasts can take control of their hosts and go on a rampage. But a strong enough host can instead summon their power at will, and an even better host can make friends with their beast.

In Justice League, Amazo (acting on Lex Luthor's orders) copies the League members' powers and handily defeats them. Then Martian Manhunter allows Amazo to copy his powers, which include mind-reading. Upon using this new ability, Amazo realizes that Luthor has been manipulating him all along, and he immediately stops fighting the League.

Logans Run. The computer was trying to drain his memories or something to find the hidden lair of the resistance groups. Instead, not only was there no "resistance", but the experiences outside the dome actually overloaded the system (c'mon it was a a rather short movie, they didn't spend that long outside).

^^You weren't here when this trope was in the formative stages. Half the text was spoilered. The consensus was that it'd be better to mark this trope as spoiler-heavy than to have half the examples be a name of a work followed by blanked-out text.

In the last episode of The Secret Saturdays, V.V Argost has assimilated the Kur powers from Zak's Evil Twin from an anti-matter Mirror Universe, and then does the same to Zak himself to become even more powerful. But what Argost didn't realize (but Zak did) was what happens when matter and anti-matter combine, and Argost obliterates himself instead.

One episode of South Park has Cartman's super high-tech Trapper Keeper begin assimilating all technology (beginning with a calculator, then a computer, then a lamp, then Cartman). "Trapper Keeper ready to ensorb." Eventually it goes on a rampage and heads for Cheyenne Mountain to ensorb the NORAD command center located there, but on the way it eats Rosie O'Donnell, weakening it enough for Kyle to turn it off.

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