"Let The Games Begin" is the second episode of the third season of ER. It first aired on NBC on October 3, 1996. It was written by Lydia Woodward and directed by Tom Moore. It has Jeanie Boulet dealing with HIV-positive status as she tries to keep it a secret. Another hospital, Southside Hospital closes down and it's employees, including new Chief of Staff Donald Anspaugh, merge with County General. Carol Hathaway has severe fianacial problems and considers seeling her house.

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Jeanie copes with the burden of being HIV-positive and gets kicked out from a trauma by Benton. Another hospital, Southside Hospital, closed down and former Southside staffers, including Dr. Donald Anspaugh, merge with County General. Carol has fianacial woes and decides whatever or not to sell her house. Mark and Susan endure disastrous blind dates.

Both Mark Greene and Susan Lewis have been on a round on unsuccessful blind dates but are enjoying each other's company whenever the opportunity arises. Doug Ross on the other hand finds it almost impossible to have any kind of an emotional relationship with a woman. Hathaway is having financial difficulties and desperately wants to sell her house. Carter sleeps in and finds he is again covering the ER while Dennis Gant gets to assist in an operation. Concerned by Jeanie Boulet's HIV status, Dr. Benton pushes her aside during a trauma leading Dr. Weaver to wonder just what is going on. All of the staff at County General is on edge as rumors fly that the hospital may be closed.