This anorexigenic neuropeptide has a plausible biological role in the regulation of food intake and energy balance, and numerous studies have demonstrated that the SNPs in POMC gene linkage with obesity-related traits.

If there is a drop in leptin levels in the blood, the ARN is stimulated to release orexigenic NPY, agouti-related peptide (AgrP), and GABA along with an inhibition of anorexigenic [alpha]-MSH (Kalra et al.

We now have the funds available to complete the toxicology program for UGP281, our lead proprietary anorexigenic peptide for the treatment of obesity, and subsequently prepare and file an Investigational New Drug Application with the FDA next year.

OTCBB: UGNE) a leader in the design, delivery, manufacture and development of peptide-based therapeutics announced today that the Company presented positive preclinical data for UGP281, its potent, orally-delivered anorexigenic peptide as a late-breaking poster presentation at the American Diabetes Association (ADA) 71st Scientific Sessions being held June 24-28 in San Diego, California.

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