Details

Tag Info: N-terminal 6xHis-tagged. MW: 68.6 kDa. Function: Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity). Subcellular Location: Cytoplasm, Nucleus. Protein Families: Nuclear hormone receptor family, NR4 subfamily. Tissue Specificity: Expressed in a number of cell lines of T-cell, B-cell and fibroblast origin. Strong expression in brain tissue.