She speculated that their relationship would have been different had Chloe been born a girl, but "that's not the way life went. That's not our journey —this is our journey now, and I feel like we've become so much closer because of it."

Despite being assigned male at birth, Chloe said that they have both suspected they were transgender throughout their childhood.

"We were putting tops on our heads to make it look like (long) hair, and tops on our bottoms to make it look like skirts -- anything we could find to make us look feminine, we would do," Jamie said. When they played together as children, they even called each other by their female names.

Slowly, Jamie said they began growing apart. By the time she became a teenager, and her sister was entering her preteen years, they no longer had much in common.

"I was going through my own thing, and she was going through her own thing," she said. "We kind of drifted apart."

By 16, Jamie —who had come out as gay two years prior —began performing in drag.

"I was always much happier in drag than out of drag," she said. "It was like going back into my childhood, and experiencing being that feminine again. I just felt so comfortable."

Through drag, Jamie said she began exploring her own gender identity. Even though their mom, who is a lesbian, has asked many times whether Jamie thought she was transgender, it was not until she began speaking with her transgender friends more did she begin questioning it.

Their next battle is coming to terms with the gender reassignment surgery.

Jamie said her hesitation was due to her fear of anesthesia and hospitals.

Chloe however, said, "to be honest, I'd do it tomorrow if that were an option," although she admitted she still has a ways to go in mentally transitioning before she is ready for the physical procedure.