"I am so proud of what we accomplished with the 'Spider-Man' franchise over the last decade," Maguire said in a statement Monday. "Beyond the films themselves, I have formed some deep and lasting friendships. I am excited to see the next chapter unfold in this incredible story."

"Working on the 'Spider-Man' movies was the experience of a lifetime for me," Raimi, who directed all three "Spider-Man" films, also said in a statement Monday. "While we were looking forward to doing a fourth one together, the studio and Marvel have a unique opportunity to take the franchise in a new direction, and I know they will do a terrific job."

Meanwhile the plagued $50 million Broadway musical 'Spider-Man' has been pushed back until this fall. The Bono-scored mega musical, the most expensive Broadway musical in history, has had financing problems and will open in November instead of March.