I am interested in the biochemistry and biophysics of membrane proteins, and my research involves structural determination and dynamic studies of ion channels and receptors that are essential to sensory signal transduction. One family of ion channel proteins that are of particular interest are the transient potential receptor (TRP) channels, generally described as the vanguard of our sensory systems that are involved in temperature sensing, taste, olfaction, chemosensation, and mechanosensation. My lab is trying to elucidate the atomic details of the channel proteins and their corresponding activation and regulation mechanism, especially their interactions with membrane-bound second messenger, both structurally and dynamically, using novel nuclear magnetic resonance (NMR) spectroscopic methods, combining with other cutting-edge spectroscopic and thermodynamic techniques (fluorescence, CD, FTIR, ITC, DSC, SPR, etc.) and computational approaches.EducationPh.D., Columbia University, New York, NY 1999M.A., Columbia University, New York, NY 1995B.S., Peking University, Beijing, China, 1994

About Yufeng Wei

I am interested in the biochemistry and biophysics of membrane proteins, and my research involves structural determination and dynamic studies of ion channels and receptors that are essential to sensory signal transduction. One family of ion channel proteins that are of particular interest are the transient potential receptor (TRP) channels, generally described as the vanguard of our sensory systems that are involved in temperature sensing, taste, olfaction, chemosensation, and mechanosensation. My lab is trying to elucidate the atomic details of the channel proteins and their corresponding activation and regulation mechanism, especially their interactions with membrane-bound second messenger, both structurally and dynamically, using novel nuclear magnetic resonance (NMR) spectroscopic methods, combining with other cutting-edge spectroscopic and thermodynamic techniques (fluorescence, CD, FTIR, ITC, DSC, SPR, etc.) and computational approaches.EducationPh.D., Columbia University, New York, NY 1999M.A., Columbia University, New York, NY 1995B.S., Peking University, Beijing, China, 1994

Positions

Present

Assistant Professor, Department of Chemistry and Biochemistry,
Seton Hall University