July 28, 2015  A new article describes a new tool that improves the ability to match drugs to disease: the Kinase Addiction Ranker predicts what genetics are truly driving the cancer in any population of cells and ... read more

July 27, 2015  In industrialized countries, acute lymphoblastic leukemia is the most common form of cancer in children. An international research consortium has now succeeded in decoding a specific form of this ... read more

July 16, 2015  Bone marrow contains stem cells that normally give rise to new red and white blood cells. A team of researchers from Sweden and France has now shown that bone marrow cells can also form ... read more

July 10, 2015  Even though the transplantation of blood stem cells, also known as bone marrow, has saved many lives over many decades, the genes that control the number or function of blood ... read more

July 9, 2015  A recently-developed drug, already used safely in adult leukemia clinical trials, holds great promise for some children with an aggressive form of cancer known as acute lymphoblastic leukemia, a new ... read more

July 9, 2015  Multiple myeloma uses a trick akin to a wolf in sheep’s clothing to grow in and spread to new bone sites. By overexpressing Runx2, a gene that normally is a master regulator of bone formation, the ... read more

July 28, 2015  The safety and dosing of a new drug for treating blood cancers has now been established by a group of scientists. The drug is a small molecule inhibitor that suppresses the activity of a signaling ... read more

July 21, 2015  The first total syntheses of certain compounds involved in excessive cell death in leukemia has been carried out by researchers. The researchers completed the total syntheses of several members of ... read more

July 13, 2015  A new compound that locks a disease-related protein into an inactive position stifled the growth of an aggressive form of leukemia in laboratory and animal tests, researchers ... read more

July 2, 2015  A mutation found in most melanomas rewires cancer cells' metabolism, making them dependent on a ketogenesis enzyme. The finding points to possible strategies for countering resistance to ... read more

July 1, 2015  Scientists have identified a group of genetic mutations in patients with aplastic anemia, which likely will help doctors optimize treatment for this rare and deadly blood condition. The study could ... read more

June 23, 2015  An America-wide clinical trial analyzes outcomes after two common treatments: bone marrow transplant and chemotherapy. The results could lead to wider access to transplants, researchers ... read more

June 23, 2015  The costs associated with cancer drug prices have risen dramatically over the past 15 years, which is of concern to many top oncologists. In a new analysis, researchers concluded that the majority of ... read more

June 18, 2015  After collecting data on a leukemia-affected family for nearly a decade, an international team of genetic researchers is tracking down a mutation partly responsible for causing the disease. Their ... read more

June 15, 2015  Rich, creamy, nutritious and now cancer fighting. New research reveals that molecules derived from avocados could be effective in treating a form of cancer. AML is a devastating disease and proves ... read more

June 15, 2015  A particular human gene variant makes breast cancer cells more aggressive. Not only are these more resistant to chemotherapy but also leave the primary tumour and establish themselves in other parts ... read more

June 10, 2015  In preliminary experiments with mice and lab-grown cells, scientists have found that a protein-signaling process accelerates the work of the gene most frequently mutated in a common form of adult ... read more

June 9, 2015  Blood and Marrow Transplantation (BMT) is a potentially curative treatment for patients with leukemia or other life-threating blood diseases. With a goal of increasing survival rates, a research team ... read more

June 8, 2015  A potentially important discovery has been made in the battle against one of the most devastating forms of leukemia that accounts for as many as one in five children with a particularly aggressive ... read more

June 5, 2015  For patients with blood cancers such as leukemia and multiple myeloma, a bone marrow transplant can be both curative and perilous. It replenishes marrow lost to disease or chemotherapy but raises the ... read more

June 2, 2015  An long noncoding RNA (lncRNA), which might give an impact on tyrosine kinase-targeted leukemia therapy, was found to be expressed in a leukemia cell line. The function of the lncRNA ... read more

June 1, 2015  Breastfeeding for six months or longer was associated with a lower risk of childhood leukemia compared with children who were never breastfed or who were breastfed for a shorter time, according to an ... read more

May 30, 2015  Because of the significant benefit found in combining the targeted drug ibrutinib with standard chemotherapy for relapsed chronic lymphocytic leukemia or small lymphocytic lymphoma, an interim ... read more

May 30, 2015  Use of the targeted agent pacritinib significantly reduced the symptoms and burden of advanced myelofibrosis in patients, says a researcher who co-led PERSIST-1, the worldwide phase 3 clinical trial ... read more

May 21, 2015  A new chemical technology uses cancer cells' own protein-degrading machinery to destroy, rather than merely inhibit, cancer proteins. Researchers developed the strategy as a way to develop ... read more