Many complex real-world problems which are difficult to understand can be solved by discrete or continuous
simulation techniques, such as Discrete-Event-Simulation, Agent-Based-Simulation or System Dynamics.
In recently published literature, various multilevel and large-scale hybrid simulation examples have been
presented that combine different approaches in common environments.

The offshore wind industry in Europe is looking to move further from shore and increase the size of wind
parks and wind turbines. As of now marine logistics during the operation and maintenance life cycle
phase is, besides wind turbine reliability, the most important limitation for wind turbine service, repair
and replacement, and pose a large risk for wind park operators and owners.

This paper proposes a multi-paradigm modeling framework (MPMF) for modeling and simulating problem situations (problems whose specification is not agreed upon). The MPMF allows for a different set of questions to be addressed from a problem situation than is possible through the use of a single modeling paradigm.

Like most countries, Canada faces rising rates of diabetes and diabetic ESRD, which adversely affect
cost, morbidity/mortality and quality of life. These trends raise great challenges for financial, human
resource and facility planning and place a premium on understanding tradeoffs between different
intervention strategies. We describe here our hybrid simulation model built to inform such efforts.

This paper discusses the development of a simulation model to mimic a return to work phenomenon of Social Security Disability Insurance (SSDI) enrollees in the United States. Agent Based and Bayesian Network methods are used within a multi-method simulation model to capture system conditions and enrollee behavior.

This paper presents preliminary analysis of the Panama Canal Expansion from the viewpoint of salinity in
the Gatun Lake and the utilization of neural networks. This analysis utilized simulation modeling and
artificial intelligence.

Due to the transition towards a sustainable energy supply, many electricity generation systems are faced with great challenges worldwide. Highly volatile renewable energy sources play an important role in the future electricity generation mix and should help compensate the phase-out of nuclear power in countries such as Germany. Simulation-based energy system analysis can support the conversion into a sustainable future energy system and are intended to find risks and miscalculations. In this paper we present main components of the electricity generation system models. We use a hybrid simulation approach with system dynamics and discrete event modules. This modular design allows quick model adoptions for different scenarios. Simulation results show the development of the future annual electricity balance, CO2 emission balance, electricty imports and exports, and the wholesale price of electricity.

This paper discusses the development of an individual based simulation of interventions for better treatment of patients with abdominal aortic aneurysms (AAA). The interdisciplinary subject required collaboration of medical doctors, Health Technology Assessment (HTA) experts and modelers.

Several challenges of port/terminal and/or ferry company managers pertain to decisions for the justification of investments and concurrent operational tasks of roll-on/roll-off passenger (RoPax) and roll-on/roll-off (RoRo) systems. This paper explores the possible uses of Modeling and Simulation (M&S) techniques as a decision-support aid for a RoPax/RoRo system managers.