Ashley had a relationship with Ray Boccino. Ray used this to his advantage when he convinced Ashley to use The Lost to steal several diamonds from Anthony "Gay Tony" Prince. In the GTA IV mission Taking in the Trash, he seemed to care about her and her addiction.

After completion of The Lost and Damned's storyline, if Johnny calls Ashley, she'll ask for forty dollars. Johnny declines, saying that she can kill herself on her own. She e-mails Johnny once more. The e-mail says that she checked into rehab, and is doing well. Johnny wishes her good luck but also tells her to stay away from him. A few in-game days later, she sends Johnny another email reluctantly confessing that she was booted out of the rehab facility and asking Johnny for yet more money, to which Johnny reinforces his wishes for her to stop contacting him. She is not heard or seen from again after this point.

The player can also occasionally call her after certain missions to hear her input on what's going on in the game's storyline.