To characterize en face features and relationship of the polyps, retinal pigment epithelial detachment (PED) and fibrovascular component in eyes with polypoidalchoroidalvasculopathy(PCV) using a swept-source optical coherence tomography (SS-OCT).

Methods

We retrospectively reviewed the medical records of all patients that presented with PCV to Hanyang university hospital from June 2013 to May 2014. Totally 40 eyes from 38 patients were included in this study. There were 35 eyes with polyps, PED and fibrovascular component simultaneously, whereas 5 eyes were present polyps and PED. Fluorescein angiography (FA) and indocyanine-green angiography (ICGA) were performed. Three-dimensional 6×6 mm macular cube scans, B-scan and en face images were obtained by using SS-OCT.

Results

In en face image, PEDs are generally ovoid, smoothly thin-walled and optically empty in 24 eyes (60%), and partially irregularly notched and distorted by contiguous polyps and fibrovascular in 16eyes (40%). Polyps mainly appears as small, well-defined, round thin-wall with moderately hyper-reflective content in en face images. The portion of the PED overlying the polyp lesion was detected in 32 eyes (80%) In addition, fibrovascular components adjacent to PEDs and polyps in B-scan image are appeared as geographic hyper-reflectivity.

Conclusions

Because en face SS-OCT imaging show frontal plane of retro-retinal structure at various depth, these scans show different aspects of detachment and its contents in relation to the section level. En face SS-OCT imaging visualized the topographic relationship of polyps, PEDs and adjacent fibrovascular tissue well