What is the possible health issue the women would face in this record?

The record for most children born to a single couple belongs to the
first wife of Feodor Vassilyev of Russia. In 27 pregnancies between
1725 and 1765 she gave birth to 16 pairs of twins, 7 sets of triplets,
and 4 sets of quadruplets for a grand total of 69 children.

This can cause a number of symptoms, including urinary incontinence (due to an increase in pressure on the bladder from less effective muscular support), and possible prolapse of the bladder, uterus, or rectum into the vagina, again due to the weakening of the pelvic floor.