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Abstract

Near-field coded aperture imaging is known to have superior image resolution and count sensitivity over conventional parallel-hole collimated nuclear imaging. There have been several studies in image reconstruction for two-dimensional planar objects using the coded aperture imaging technology. However, coded aperture imaging for three-dimensional (3D) objects has not been extensively investigated. In this paper, a 3D reconstruction method for near-field coded aperture imaging is presented. We first introduce the "out-of-focus" correction factor into the generic expectation maximization (EM) algorithm for 3D near-field coded aperture images with the assumption that the photon emissions of coded aperture projections follow the Poisson statistics. The ordered subset expectation maximization (OSEM) method is then adapted for full 3D coded aperture image reconstruction. A 3D capillary tube phantom filled with 99mTc radioactive solution was used to evaluate the performance of our methods. A dual-head SPECT camera, one head quipped with a coded aperture module and the other with a parallel-hole collimator, was utilized for image acquisitions. Images were reconstructed using the modified EM and OSEM methods associated with the depth-dependent out-of-focus correction. The preliminary phantom results showed that our methods may have potential of reconstructing 3D near-field coded aperture images and also providing superior image resolution as compared to conventional parallel-hole collimated images.

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Journal of Applied Remote SensingJournal of Astronomical Telescopes Instruments and SystemsJournal of Biomedical OpticsJournal of Electronic ImagingJournal of Medical ImagingJournal of Micro/Nanolithography, MEMS, and MOEMSJournal of NanophotonicsJournal of Photonics for EnergyNeurophotonicsOptical EngineeringSPIE Reviews