While the control of cell migration by biochemical and biophysical factors is largely documented, a precise quantification of cell migration parameters in different experimental contexts is still questionable. Indeed, these phenomenological parameters can be evaluated from data obtained either at the cell population level or at the individual cell level. However, the range within which both characterizations of cell migration are equivalent remains unclear. We analyse here to which extent both sources of data could be integrated within a unified description (...) of cell migration by considering the motility of the endothelial cell line EAhy926. Using time-lapse video-microscopy and associated analysis of digital image time series, we quantified EAhy926 random motility coefficient, migration speed and trajectory persistence time in two different migration assays: the in vitro wound healing assay, and the cell-populated agarose drop assay. In order to analyse the agreement between independent quantifications of cell motility based either on individual cell analysis or cell population dynamic analysis, a theoretical multi-agents cellular model was developed and discussed as a possible theoretical framework able to unify these multi-scale data. Model simulations especially reveal the potential bias induced by cell proliferation and cell-cell adhesion when cell migration parameters are estimated from the extensively used in vitro wound healing assay. (shrink)

The present study is an attempt to relate the multicomponent response of the cytoskeleton (CSK), evaluated in twisted living adherent cells, to the heterogeneity of the cytoskeletal structure - evaluated both experimentally by means of 3D reconstructions, and theoretically considering the predictions given by two tensegrity models composed of (four and six) compressive elements and (respectively 12 and 24) tensile elements. Using magnetic twisting cytometry in which beads are attached to integrin receptors linked to the actin CSK of living adherent (...) epithelial cells, we specifically measured the elastic CSK response at quasi equilibrium state and partitioned this response in terms of cortical and cytosolic contributions with a two-component model (i.e., a series of two Voigt bodies). These two CSK components were found to be prestressed and exhibited a stress-hardening response which both characterize tensegrity behaviour with however significant differences: compared to the cytosolic component, the cortical cytoskeleton appears to be a faster responding component, being a less prestressed and easily deformable structure. The discrepancies in elastic behaviour between the cortical and cytosolic CSK components may be understood on the basis of prestress tensegrity model predictions, given that the length and number of constitutive actin elements are taken into account. (shrink)

Radical Orthodoxy, a growing movement among contemporary Christian theologians, argues that the prominent philosophical paradigms of modern and postmodern thought lack transcendence, are ultimately nihilistic, and are guided by an ontology of violence. Among the thinkers Radical Orthodoxy criticizes are Hegel, Nietzsche, and Hobbes, but surprisingly also the Jewish philosopher Emmanuel Levinas, whom they claim offers an ethics for nihilists. In this essay, I analyze the claims of two prominent thinkers in Radical Orthodoxy, John Milbank and Catherine Pickstock, and argue (...) that their account of Levinas is not only unfounded but point out the ways in which Levinas himself is also just as critical of the prevailing ontology of violence that figures in modern accounts of intersubjectivity and politics. Indeed, in his own way, Levinas also offers an ontology of peace, making him an important dialogue partner for Radical Orthodoxy's construction of an alternative ethics and politics. (shrink)

In this article, I re-evaluate critiques of Levinas's Eurocentrism by exploring his openness to decolonial theory. First, I survey Levinas's conceptual confrontation with imperialism, showing that his early Eurocentric work (1930s-1960s) is revised in his later writing (1970s-1980s). Second, I explore the contextual reasons that led him to take that path, such as his previously overlooked conversations with the liberationist South American intellectual Enrique Dussel. Finally, I present the case for a revisitation of the current theoretical frameworks of Jewish thought. (...) I explain how Levinas's encounter with Third World discourses helps to add a needed decolonial layer to contemporary Jewish intercultural conversations. (shrink)

The phenomenological ethics of Emmanuel Levinas challenges fundamental assumptions regarding the ethical and ontological nature of interpersonal relationships. Although Levinas did not address the specific ethical realities of enduring intimacy, the existential anthropology of Martin Buber is used to explore the implications of Levinas' ethic for enduring intimate relationships. These philosophers call for a reexamination of some of our basic assumptions about being a couple, and challenges us to articulate a more meaningful description of what it means to be a (...) couple. 2012 APA, all rights reserved). (shrink)

The controversial case of Terri Schiavo came to a close on March 31, 2005, with her death following the removal of a percutaneous endoscopic gastrostomy tube. This event followed years of controversy and social upheaval. Voices from across the entire political and cultural spectrums filled the airwaves and op-ed pages of major newspapers. Protests ensued outside of Ms. Schiavo’s care facility. Ms. Schiavo’s parents published videos of their daughter on the internet in an effort to prove that she was not (...) in a vegetative state and could potentially recover. There is a certain mystery to the entire controversy given the fact that, legally, it was largely a matter of settled law. Precedent cases and legal statutes clearly set out the proper procedures and decisions to be followed in this case. Nonetheless, powerful challenges and virulent opposition to these standards arose. Through an investigation of this case as well as a comparative study of the case of Dax Cowart (in particular, the documentary depictions of Dax Cowart’s case) and of a photograph by Joel-Peter Witkin, I plan to investigate the source of these social upheavals and hypothesize that they were largely the result of a phenomenological reaction to the human face. (shrink)

Emmanuel Levinas (1905-1995) is at the center of the renewed debate over the question of the ethical. In the context of the phenomenological tradition, Levinas defines ethics as an originary response to the face of the other. Between 1982 and 1992, Levinas gave numerous interviews, closing a distinguished sixty-year career. Of the twenty interviews collected in this volume, seventeen appear in English for the first time. In the interviews Levinas sets forth the central features of his ethical philosophy. He underlies (...) his dedication to the phenomenological search for the concrete and the nonformal signification of alterity. He also elaborates on issues that do not receive extensive treatment in his formal philosophical works, including the question of pre-philosophical experiences, the ethical signification of money, justice, and the State. The informality of the interviews prompt Levinas to address matters about which he is reticent in his published works. (shrink)

: Emmanuel Levinas compares ethical responsibility to a maternal body who bears the Other in the same without assimilation. In explicating this trope, he refers to a biblical passage in which Moses is like a "wet nurse" bearing Others whom he has "neither conceived nor given birth to" (Num. 11:12). A close reading of this passage raises questions about ethics, maternity, and sexual difference, for both the concept of ethical substitution and the material practice of mothering.

Critics of Levinas reject the notion that the abstract face of the other can ground ethics and generate specific responsibilities. To the contrary, I argue that the face does ground a practical and pragmatic ethics. Drawing on Levinas' phenomenological analyses of the enjoying subject, I show that the face communicates an imperative to the subject that obligates her or him to repair the concrete context of action in which the subject encounters the other. My elucidation takes very seriously the notion (...) that the face speaks and the face is a body. When coupled with a pragmatic account of communication, Levinas gives us a robust elucidation of the phenomenological and pragmatic dimensions of ethical responsibility. Key Words: embodiment  ethics  face  Emmanuel Levinas  phenomenology  pragmatics  responsibility. (shrink)

For Emmanuel Levinas objectivity is intersubjectively constituted. But this intersubjectivity is not, as in Merleau-Ponty, the intercorporeality of perceivers nor, as in Heidegger, the active correlation of practical agents. It has an ethical structure; it is the presence, to each cognitive subject, of others who contest and judge him. But does not the exposure of each cognitive subject to the wants and needs of others result in the constitution of a common practical field, which is not yet the objective world (...) of scientific cognition? For Levinas, the constitution of a world common to all is governed by the practice of justice. Justice begins when above the elf and the other there intervenes a third party, who contests and judges both. But whether this third party is a representative of humanity, or a figure of God, would not his justice be but the name of a higher egoism? (shrink)

The Face of the Other and the Trace of God contain essays on the philosophy of Emmanuel Levinas, and how his philosophy intersects with that of other philosophers, particularly Husserl, Kierkegaard, Sartre, and Derrida. This collection is broadly divided into two parts: relations with the other, and the questions of God.

From the relative obscurity in which Levinas's work languished until very recently, Emmanuel Levinas must now be judged as one of the most influential figures in contemporary Continental philosophy. There is no better guide than John Lewelyn to lead one through the thickets of Levinas's prose. Bursting with questions, multiple references, cascading citations and multilingual puns and nuances, this book is the compelling record of intellectual obsession. Taking as its guiding thre the theme of genealogy, the book gives a broadly (...) chronological and impressively manageable presentation of the whole sweep of the Levinas's work. Balanced and finely grained, Llewelyn confronts questions of method, Heidegger, phenomenology, the theme of sensibility, religion, enjoyment, feminity, eros, justice and the political. The book reaches a stunning climax in a series of chapters that give a hestitant but tolerant discussion of the question of God in Levinas, the relation to Levinasian ethics to Nietzschean genealogy, and an extraordinary discussion of metaphor that leads into a wholly original analysis of Levinas's poetics and metaphorics. The book concludes with a sensitive reading of the autobiographical epigraphs to Levinas's Otherwise than Being... and a consideration of the Holocaust. (shrink)

In 1982 the American philosopher and Levinas scholar Edith Wyschogrod conducted an interview with Emmanuel Levinas, the transcript of which she published seven years later. Early in the interview, Wyschogrod proposed to Levinas that his philosophy constituted a radical break with western theological tradition because it started not with a Parmenidean ontological plenitude, but rather with the God of the Hebrew Bible. The God Levinas began with, according to Wyschogrod, wasan indigent God, a hidden God who commands that there be (...) a world apart from God, because God needs the multiplicity of the world in order for there to be justice. Levinas responds to this proposal: That’s quite right. Justice, I call it responsibility for the other, right? There is even in Totality and Infinity, the evocation of the tzimtzum [the idea in kabbalistic writings of the self-contraction of God in order to create the void in which creation can take place], but I won’t venture into that. (shrink)

Ethics as First Philosophy brings together original essays by an outstanding group of international scholars that discuss the work of Emmanuel Levinas. The book explores the significance of Levinas' work for philsophy, psychology and religion. Ethics as First Philosophy comprises an excellent collection of work on this major contemporary thinker. The book presents Levinas philosophy from a wide and well-balanced variety of perspectives. The contributions range from thematic discussions of Levinas central concepts to explorations of his affinities and differences with (...) other key writers such as Kant, Kierkegaard, Rosenzweig, Benjamin, Blanchot and Derrida. Some of the authors focus on the religious and philosophical issues presented by Levinas while others analyze the role of Levinas within phenomenology in or within recent French philosophy. (shrink)

Emmanuel Levinas (1905-1995) was one of the foremost thinkers of the twentieth century. His work influencing a wide range of intellectuals such as Maurice Blanchot, Jacques Derrida, Luce Irigaray and Jean-Luc Marion.

The present paper aims to view three ways of thinking time by Emmanuel Levinas. We distinguish existential, historical, and eschatological time demonstrating how they are connected with his central notion of responsibility toward the Other. The following analysis reorders and interprets what Levinas has said in response of Martin Heidegger’s and Hegel’s position. The text does not make any other claims but aims to offer a possible reading and exegesis of Levinas’s philosophy and open a further discussion on these topics.

Leo Strauss and Emmanuel Levinas, two twentieth-century Jewish philosophers and two extremely provocative thinkers whose reputations have grown considerably over the last twenty years, are rarely studied together. This is due to the disparate interests of many of their intellectual heirs. Strauss has influenced political theorists and policy makers on the right while Levinas has been championed in the humanities by different cadres associated with postmodernist thought. In Leo Strauss and Emmanuel Levinas: Philosophy and the Politics of Revelation, Leora Batnitzky (...) brings together these two seemingly incongruous contemporaries, demonstrating that they often had the same philosophical sources and their projects had many formal parallels. While such a comparison is valuable in itself for better understanding each figure, it also raises profound questions in the current debate on the definitions of 'religion', suggesting new ways that religion makes claims on both philosophy and politics. (shrink)

This paper explores Emmanuel Levinas' Jewish writings, and in particular, his Talmudic commentaries and essays on Judaism. The aim is to elicit some salient features of his methodological approach to the Jewish sacred texts. In general, Levinas' specific reflections on method (in terms of reading the Jewish Scriptures) are confined to sporadic, fragmentary comments interspersed throughout his writings. In extracting these reflections, a specifically Levinasian approach emerges. In particular, his approach shows how one may ethically encounter the Other(s) in these (...) sacred texts. (shrink)

Edith Wyschogrod presents the first full-length study in English of the important contemporary French philosopher Emmanuel Levinas. It is a revision of the author’s earlier study and includes discussions of his recent writings as well as current scholarship. Dr. Wyschogrod’s extensive discussion of Levinas's relation to Judaism, especially his use of literature from the Torah and other religious writings, will be of interest to religious scholars. The author compares Levinas’s thought with that of his contemporaries, most notably Jacques Derrida and (...) Husserl. (shrink)

This paper examines the extent to which certain aspects of the philosophies of Emmanuel Lévinas and Jean-Luc Marion are directed toward the divine, especially in regard to how they employ religious imagery or even explicitly biblical metaphors, namely those of the face of the neighbor, the glory of the Infinite, the response of the witness, and the breaking or sharing of bread. This will show important parallels and connections between their respective works, but it will also highlight where they diverge (...) from each other. In respect to all four symbols or (biblical) images, I suggest that while it is indeed one (or even the primary) goal of Marion’s work to open phenomenological discourse to enable talk about the divine, Lévinas is instead interested in emptying biblical language of its theological import for purely philosophical (or ethical) purposes. (shrink)

This paper concerns the possibility of “thinking” God, and uses the work of Emmanuel Levinas to frame a contemporary approach to some of the problems involved. The difficult relationship between philosophy and Christian theology is noted, before Levinas’s thought is examined as it relates to that which both marks consciousness and exceeds it. Levinas’s adoption of the “idea of the Infinite” and hisexploration of two ways in which the Infinite might signify (have meaning) open up a useful trajectory for a (...) thought of God which is not reductive. At the same time, however, this aporetic approach raises difficulties in the context of specific religious traditions. Three problems as they occur for Christian theology are examined in the light of Levinas’s work: the problem of not being able to identify an experience of God as such; the problem of the infinite interpretability of revelation; and the problem of understanding the divinity of Jesus Christ. (shrink)

The natural world’s myriad differences from human beings, and its apparent indifference to human purposes and ends, are often regarded as problems an environmental ethics must overcome. Perhaps, though, ecological ethics might instead be re-envisaged as a form of other-directed concern that responds to just this situation. That is, the recognition of worldly (in)difference might actually be regarded as a precondition for, and opening on, any contemporary ethics, whether human or ecological. What is more, the task of ethics might be (...) regarded as one of conserving (at least some) such differences. The work of Iris Murdoch and the “difference ethics” of Emmanuel Levinas seem to offer possible ways to express such understandings. However, their ecological potential and theoretical limits, especially in terms oftheir metaphysical presuppositions, remain relatively under-explored. A closer examination of their work is presented in order to illustrate some of the possibilities and difficulties facing an ecological form of difference ethics. (shrink)

In his review of my book, Le voyage de Nietzsche à Sorrente, Emmanuel Salanskis writes that it is an agreeable read and philologically precise, but that it presents some philosophical difficulties.The first alleged difficulty lies in the conception of “epiphany.” Salanskis asks, “Can we really include Nietzsche among adherents of an aesthetics of the ‘instant’ (170) like Virginia Woolf ?” No, certainly not. On the page cited, I discuss James Joyce’s conception of epiphany (and mention Virginia Woolf only in passing) (...) in order to distinguish Joycean epiphanies and the aesthetics of the instant from Nietzsche’s epiphanies. The latter, I argue shortly thereafter, are “from an epistemological point of view not moments .. (shrink)

Abstract In this article, I attempt to trace Emmanuel Levinas's notion of transcendence and its relation to infinity to his Talmudic lectures to offer both a philosophical diagnosis as well as a counter to the essentialist logic of what Levinas considers the traditional or ?metaphysical? concept of time. This opens my speculative argument up to two levels of interpretation as it requires an historical investigation into the cultural context that conditioned Levinas's particular understanding of transcendence and infinity in relation to (...) his turn toward Talmud and sacred Jewish texts in the years following World War Two. But it also requires that we take seriously the critique of history as inadequate to such a task that is inherent in Levinas's presentation of these concepts. All of this hinges on the role and place of ?time? in Levinas. I consider Levinas's category of ?time immemorial? as a counter to the essentialist logic of what Levinas considers the traditional or ?metaphysical? concept of time which I claim is at the core of the ?realist? attitude toward the practice of history founded upon the categories of agency, experience, memory, testimony, and most recently the importance of ?presence?. This in turn leads me to propose two possible alternatives, through Freud and Derrida, that conserve Levinas's critique of the essentialist understanding of time uncoupled from any transcendent or theological mechanism. (shrink)

Ch. 1: Inadequate approaches to the question of God -- 1.1. Initial clarifications -- 1.2 Wholly unsystematic direct approaches -- 1.3. Semi-systematic indirect approaches -- 1.4. A wholly anti-systematic, anti-theoretical, and direct approach: Ludwig Wittgenstein -- 1.5. A characteristic example of a failed critique: Thomas Nagel's objections to God as "last point" -- Ch. 2. Heidegger's thinking of Being: the flawed development of a significant approach -- 2.1. Heidegger's failed and distorting interpretation and critique of the Christian metaphysics of Being (...) -- 2.2. Heidegger's four approaches to "retrieving" the "question of being" -- 2.3. What is unthought in Heidegger's thinking of Being I: Being-as-Ereignis -- 2.4. What is unthought in Heidegger's "thinking of Being" II: Being and being(s)- Ereignis and Ereignete(s) -- 2.5. The "overcoming [Überwinding] of metaphysics" as "transformational recovering [Verwindung]" of metaphysics and "the end of the history of Being" -- 2.6. The status of Heideggerian thinking I: thinking of Being as thinking within Ereignis, thinking that reaches its destination with Ereignis (Denken, das in das Ereignis einkehrt) -- 2.7. The status of Heideggerian thinking II: absolute claim, provisionality, the poverty of language, the language of thinking, the finitude of thinking -- 2.8. Heidegger's thinking and the topic "God" -- 2.9. Heidegger's "thinking": a fundamentally deficient and confused form of thinking -- Ch. 3:The structural-systematic approach to a theory of Being and God -- 3.1. The systematic context: the theoretical framework of the structural-systematic philosophy -- 3.2. The unrestricted universe of discourse as the universal dimension of primordial Being -- 3.3. Explication of the dimension of Being I: theory of Being as such -- 3.4. Explication of the dimension of Being II: theory of Being as a whole -- 3.5. Explication of the relation between absolutely necessary Being and the contingent dimension of Being as key to a conception of absolutely necessary Being as minded (as personal) -- 3.6. Absolutely necessary minded (personal) Being as creator of the world (as absolute creating) -- 3.7. The clarified relation between Being and God and the task of developing an integral theory about God -- Ch. 4: Critical examination of two counterpositions: Emmanuel Levinas and Jean-Luc Marion -- 4.1. Levinas's misguided conception of transcendence "beyond B/being" -- 4.2. Jean-Luc Marion's failed conception of "radical and non-metaphysical transcendence" and of "God without Being". (shrink)

This article addresses Emmanuel Levinas's re-conceptualization of Jewish identity by examining his response to a question he himself poses: “In which sense do we need a Jewish science?” First, I attend to Levinas's critique of modern science of Judaism, particularly as it was understood in the critical approaches of the nineteenth-century school of thought, Wissenschaft des Judentums. Next, I detail Levinas's own constructive proposal that would, in his words, “enlarge the science of Judaism.” He retrieved classical textual sources that modern (...) Judaism had neglected, while at the same time he enlarged Judaism's relevance beyond a historical community by turning to phenomenology as a rigorous science. Finally, I conclude with some reflections on the broader implications of this new science of Judaism for Jewish ethics and identity in a post-war period. (shrink)