It is an NMDA receptor antagonist which slows the development of Alzheimer's disease by decreasing Ca into the cell.

1) What is the physiological behind Parkinson's Disease?

2) Name some signs and symptoms

3) What is the pharmacology behind this?

You have a loss of dopamingeric neurons originating in the substantial nigra and terminating in the striatum. This means you have a decrease of inhibition from dopamine and constant excitation from acetyl choline.

2) This leads to tremors and shaking. Some non-motor issues are anxiety and depression.

3) You want to increase the dopamine and decrease acetyl choline. You need to have a balance b/w the two for tone.

1) How does L-Dopa aid with Parkinson's disease?

2) How long does it take to become effective?

1) It is a DA precursor drug. It can cross BBB unlike dopamine and it metabolized there by dopa decarboxylase.

2) 6 months

** Remember to come slowly or parkinsonism.

1) How does Carbidopa aid in Parkinson's disease?

2) Name the side effects, interactions, contraindications.

1) Blocks dopa decarboxylase peripherally so more L-Dopa can cross the BBB