765asebḗs (an adjective which is the negation of 4576/sébomai, "to respect") – properly, lack of reverence ("without due respect"), i.e. failing to honor what is sacred – especially in the outward (ceremonial) sense.

[765 (asebḗs) is the antonym (opposite) of 4576/sébomai ("respecting what is holy").]

1 Timothy 1:9Adj-DMPGRK:καὶ ἀνυποτάκτοις ἀσεβέσι καὶ ἁμαρτωλοῖςNAS: and rebellious, for the ungodly and sinners,KJV: disobedient, for the ungodly andINT: and insubordinate [ones] for [the] ungodly and sinful