Pattern of Pediatric Oncology Cases in the Western Region of NepalThe objective of this study was to establish the pattern of childhood cancers in the
Western region of Nepal. We reviewed cases receiving external radiotherapy with both palliative and curative intent
between 28th September 2010 and 30th September 2015 at the Department of Radiotherapy and Oncology, Manipal
Teaching Hospital affiliated with Manipal College of Medical Sciences, Pokhara, Nepal. Of the total of 1217 cases,
2.71% involved children. The gender distribution showed a male preponderance (M:F= 1.35:1). The patients’ mean
age was 11.4 years (range 2 - 14 years). Considering the caste, Brahmins and Gurungs cons...Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Knowledge and Perceptions about Cancer Treatment-associated Infertility among Young Patients at a Tertiary Care Hospital in PakistanIn this study we assessed knowledge and perceptions among young cancer patients regarding the topic of cancer and
infertility related to different treatment options. Material and Methods: This cross-sectional study was conducted on
young cancer patients in the Clinical Oncology Department, JPMC, Karachi, from January to August 2013. Patients were
requested to fill in questionnaires. Comparisons between gender and age groups were performed using the Student’s
t test and Pearson’s Chi-squared. Significance was concluded with a two tailed p-value less than 0.05. Results: The
survey included 368 cancer patients, 19...Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Seroepidemiological Study of Hepatitis B, C and HIV among Blood Donors in KermanConclusion: Blood-borne viral infections in people with low education levels were more
common. The prevalence in Kerman province was low as compared to previous studies carried out in other regions of
Iran. Application of standard operating procedures, with updated equipment, as well as planning for the use of molecular
methods are necessary for the Iranian Blood Transfusion Organization, to monitor blood-transmitted infections.
PMID: 29286218 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Quality of Life Determinants in Breast Cancer Patients in Central Rural IndiaConclusions: The present study demonstrated a moderate QOL in women with breast
cancer in rural India. Young age, lack of education and being without a partner were negatively related to QOL, and
employment as casual and industrial workers, high monthly family income and higher self-efficacy were positively
associated with QOL. A comprehensive public health initiative is required, including social, financial and environmental
support, that can provide better QOL for breast cancer survivors.
PMID: 29286227 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Effects of Damnacanthal and Nordamnacanthal on Proliferation, Apoptosis, and Migration of Oral Squamous Cell Carcinoma CellsThe objectives of this study were to evaluate cytotoxicity, morphological
changes, cell death mode (apoptosis/necrosis), and cell migration induced by DAM and NDAM on the most common
type of oral cancer, oral squamous cell carcinoma (OSCC)cells. Anti-proliferative effects of these compounds against
OSCC cell lines were determined by MTT assay. The mode of cell death was analysed by phase contrast and fluorescent
microscopy as well as flow cytometry. In addition, cell migration was assessed. The results showed that DAM and
NDAM exerted cytotoxicity against OSCC cells with IC50 values of 1.9 to>30 μg/ml after 72 h trea...Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Synergistic Effect of Forbesione From Garcinia hanburyi in Combination with 5-Fluorouracil on CholangiocarcinomaThis study aimed to
investigate the synergistic effects of forbesione combined with 5-fluorouracil (5-FU) in hamster cholangiocarcinoma
(Ham-1) cells both in vitro and in vivo. The anti-tumor effects of 5-FU combined with forbesione in vitro were determined
using the Sulforhodamine B (SRB) assay and the effects in vivo were assessed in transplanted Ham-1 allograph
models. Using ethidium bromide/acridine orange (EB/AO) staining, the morphological changes of apoptotic cells
was investigated. The expressions of apoptosis-related molecules after combined treatment with forbesione and 5-FU
were determined using real-time RT-PCR...Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Human Papilloma Virus Genotype Distribution in Cervical lesions in Zanjan, IranConclusion: While HPV infection is the major etiological factor for cervical cancer, presence was relatively low in
our survey. In the positive cases, however, HPV18 was the most common in line with many other populations. The fact
that types vary among different populations must clearly be taken into account in design of vaccines for our country.
PMID: 29286606 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Limited Understanding of Pap Smear Testing among Women, a Barrier to Cervical Cancer Screening in the United Arab EmiratesAuthors: AL-Hammadi FA, Al-Tahri F, Al-Ali A, Nair SC, Abdulrahman M
Abstract
Global data indicate that cervical cancer is the fourth most common cancer among women worldwide. Important
factors that affect interventions for early diagnosis of cervical cancer include social beliefs and values and poor
knowledge. These may contribute to women’s participation in screening for cervical cancer and have a significant
impact on decisions to take preventive action. The present study was conducted with 599 women in the UAE between
September 2016 and March 2017. A cross-sectional survey was conducted to determine knowl...Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Dual Function of Gold Nanoparticles in Synergism with Mitoxantrone and Microwave Hyperthermia Against Melanoma CellsThis study was performed to evaluate any synergetic effects of mitoxantrone (MX) and gold
nanoparticles (GNPs) as dual therapeutic approach, along with microwave (MW) hyperthermia for melanoma
cancer. Methods: Various tests were performed on the DFW melanoma cell line in the presence of MX and different
concentrations of GNPs, with and without MW irradiation. MTT [3-(4,5-dimethylthiazol–2-yl)-2,5-iphenyltetrazolium
bromide] assays were conducted to evaluate the effectiveness of the used therapeutic methods in terms of cell survival.
Relative lethal synergism (RLS) was calculated as the ratio of cell death following h...Source: Asian Pacific Journal of Cancer Prevention - November 29, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Modulatory Effects of Chemoradiation on Angiogenic Factors and Laminin in Cervical Cancer: Link with Treatment ResponseAuthors: Sharma M, Khan R, Aggarwal M, Sharma A
Abstract
Objective: Carcinoma of the uterine cervix is either the first or second most common malignancy in Indian women,
depending on the registry. Tumor growth and metastasis primarily are determined by angiogenesis and parameters
of the molecular environment including extracellular matrix elements, growth factors and cytokines. Effects of
chemo-irradiation on biomarkers like vascular endothelial growth factor (VEGF), angiopoietin-2 (Ang-2) and laminin
in patients with carcinoma cervix therefore need to be explored. Methods: Circulatory and mRNA levels of VEGF,
Ang-...Source: Asian Pacific Journal of Cancer Prevention - November 29, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Predicting Intention Perform Breast Self-Examination: Application of the Theory of Reasoned ActionConclusion: TRA could be a suitable model to predict
BSE intentions . Participants who believed that doing BSE regularly is beneficial for early diagnosis of breast cancer
and also believed that their significant referents think that doing BSE would significantly detect breast cancer earlier,
were more likely to intend to perform BSE regularly. Therefore, the research findings supported the conclusion that
promoting the importance of BSE at the community/social level would enhance individuals to perform BSE routinely.
PMID: 29172263 [PubMed] (Source: Asian Pacific Journal of Cancer Prevention)Source: Asian Pacific Journal of Cancer Prevention - November 29, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research