A disease of the lungs caused by chronic inflammation of the airways most often caused by allergies. This inflammation results in airway swelling and hyperactivity leading to difficulty breathing, shortness of breath, dry cough, etc.
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2

CF vs asthma:
There is some overlap. Kids with CF often have other symptoms besides their respiratory ones, like oily stool, failure to gain weight, diarrhea. They can also get frequent bacterial lung infections that children with asthma do not often get. They also tend to produce phlegm that is thicker, white/green and looks more like pus, than the white/clear phlegm that children with asthma produce.
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3

Confusing question:
Patients with any of the listed conditions can have an infection or infestation by a common pathogen (they can all get strep throat).There is no unifying pathogen that causes all the conditions listed. Perhaps your question is really something else and the words are not quite able to address it.
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4

Maybe:
Surprisingly, M470V is a common variation. Studies have shown 50% of the population has this mutation and actually less likely to cause CF. Most individuals with CF and carry M470V have some other hidden etiology that is the cause, rather than M470V. Genetic expression may be variable and so will be the clinical manifestations. Speak with your doc and a geneticist for specific information.
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5

Yes but:
Yes but with early diagnosis and regular care and adherence to prescribed therapy by a pediatric pulmonologist the long term survival has improved greatly in the past two decades.
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6

Depends on genes:
The risk of acquiring cystic fibrosis (CF) depends on whether the parents of a child are carriers for the gene. It is estimated that about 1 in 20 americans are carriers of the CF gene. In order for a child to acquire the disease, both parents must be carriers. If both parents are carriers, there is then a 25% chance that the child will acquire the disease.
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9

Cough, poor growth:
Common symptoms of cystic fibrosis include cough, wheeze, recurrent lung infections, poor growth, foul smelling stools, salty sweat, clubbing, and rectal prolapse. The more symptoms the greater the chance of having cystic fibrosis. Most infants today are diagnosed by newborn screening for CF before they develop any symptoms and early therapy can minimize disease symptoms.
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10

Sweat test:
The gold standard to diagnose cystic fibrosis is the sweat test, which measures the amount of chloride in the sweat. The test takes a few minutes to an hour and is painless. It is done in specialized clinics and hospitals.
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13

Recessive gene:
A mutation is carried in the dna of both unaffected parents & that matching or similar mutation is paired up at conception when the sperm & egg form completed chromasomes with the defective info. Late in pregnancy and after delivery, the effect of the CF gene abnormality begins to reveal itself. In carriers, the good gene compensates for the bad & no problems occur.
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14

Recessive genes:
A mutation is carried in the dna of both unaffected parents ; that matching or similar mutation is paired up at conception when the sperm ; egg form completed chromasomes with the defective info. Late in pregnancy and after delivery, the effect of the CF gene abnormality begins to reveal itself. In carriers, the good gene compensates for the bad ; no problems occur.
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17

Progressive disease:
Cystic fibrosis (CF) is a progressive, lifelong condition in which the glands that produce mucus, sweat, and intestinal secretions do not function properly. Thick mucus accumulates in the lungs, leading to breathing difficulty and infection. CF also impairs digestion, and affected males are usually infertile.
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18

Cystic fibrosis (CF):
An inherited condition that affects the cells that produce mucus, sweat and digestive juices. These secreted fluids are normally thin & slippery. But in cf, a defective gene causes the secretions to become thick and sticky. Instead of acting as a lubricant, the secretions plug up tubes, especially in the lungs and pancreas. Treatments are aimed at preventing lung infections & improving nutrition.
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20

Organ Donation:
Organ donation is possible and should be discussed with Lifelink. Many people do not realize that other useful tissues like heart valves, tendons, corneas are part of the donation process as well and can help recipients. In CF lungs heart, pancreas and liver are likely not able to be shared.

21

Recessive:
Cystic fibrosis (CF) requires both copies of the gene to carry a mutation (one copy each from mother and father). The way a person usually gets CF is if both of their parents are unaffected carriers (one mutated copy and one normal copy). In this situation, there is a 25% chance that the offspring will get cf, 50% chance of being an unaffected carrier, and a 25% of inheriting two normal copies.
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22

As a carrier:
Genetic carrier testing: more than 10 million americans are symptomless carriers of the defective CF gene. This blood test can help detect carriers, who could pass CF onto their children. To have cystic fibrosis, a child must inherit one copy of the defective CF gene from each parent.
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23

Why?:
If you are 45 and have not manifested signs of cystic fibrosis then you don't have it and need not worry. The disease is a genetic defect that requires both genes of the pair to be effected to manifest itself. If you and your partner each carry one defective gene then 25% of your children on average could be affected. See: http://en. Wikipedia. Org/wiki/cystic_fibrosis

24

Yes:
Yes it is possible. Presentation of cystic fibrosis varies greatly, and it is possible, depending on your specific mutation (and other factors) to present at a later age. In order to prevent late diagnoses, all states now have a newborn screen in place for cystic fibrosis.
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26

Overall 1/3700:
Acording to the CF foundation: the overall birth prevalence is 1/3700. It can occur in any race, however the greatest incidence is in caucasians of northern european descent, being 1/2500. The other major groups affected are hispanics 1/13500, african americans 1/15000.More than 10 million of us carry one part of the defective gene, but to have the disease you must have a copy from both parents.
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27

Kind of...:
Cystic fibrosis (CF) is a genetic disease. Patients with the disease are born with a defective gene that is part of the body's system for making mucus, sweat, and digestive fluids. Their mucus is therefore abnormally thick and causes blockages in the lungs, pancreas and other organs that damage them and make them prone to infections and other problems.
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28

Testing; can be:
Cystic fibrosis (CF) can be diagnosed with appropriate examination by a doctor and a sweat chloride testing. No single symptom is unique to that disease. CF can be deadly, at any age, young or old. Severity varies greatly, and lung (respiratory) failure is the most common cause of death from cf.
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30

Stinky, runny poo:
No enzymes= poor or no absorption of food products. Poor absorption = bulky stinky stool that are partially digested by the germs in your gut, and significant weight loss for you as your body begins to self destruct.
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A genetic disorder of the lungs and digestive tract. It causes recurrent lung infections and inhibits growth in patients and average life expectancy of patients with cystic fibrosis is approximately 40 years.
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