Henoch-Schonlein Purpura

Definition

Henoch-Schonlein purpura (HSP) is
inflammation of the blood vessels in the skin and other body organs. When it involves the skin, it causes a telltale rash. The rash looks like bruising or small dots in the skin, referred to as purpura.

Causes

HSP is caused by an abnormal reaction of the immune system. Normally, the immune system marks and attacks foreign items like viruses and bacteria. However, with HSP, the immune system attacks the blood vessels. It is not clear why the immune system attacks the body.

The change in the immune system may be triggered by:

Bacterial or viral infections

Certain medications

Recent exposure to certain vaccines

Infection by insect bites

HSP occurs most often after a respiratory infection. HSP is not contagious.

Risk Factors

HSP is most common in children aged 2 to 11 years old, but it can occur at any age.
Factors that increase your risk of HSP include:

Revision Information

This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.