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The Safari update is more substantial, while the other programs are getting a handful of new features and fixes.

Note that, for now at least, Safari 6 is only available on Macs running the new Mountain Lion operating system update. There is currently no upgrade path if you're using Windows or a previous version of OS X.
The product page on Apple's Web site says, "The latest version of Safari is available in Mountain Lion. The latest version of Safari for Lion is available through Software Update."