Cutting down on vendor prefixes

Most web developers currently use vendor prefixes in CSS to enable certain features in some browsers. That’s fine, but sometimes I see code examples and prefix-adding tools that go a bit overboard with the support and add every possible prefix that has ever been in use (and sometimes even ones that were never used). I think there are a bunch of CSS properties that we can safely stop using vendor prefixes for, or at least considerably cut down on the number of prefixes.