HOUSTON -- (September 24, 2012) -- Comprehensive genomic analysis of breast tumors revealed four main subclasses of breast cancer, each of which has extensive genetic heterogeneity, said an international consortium of scientists in The Cancer Genome Atlas Network that included those from...

(SACRAMENTO, Calif.) — Scientists affiliated with the UC Davis MIND Institute have discovered how a defective gene causes brain changes that lead to the atypical social behavior characteristic of autism. The research offers a potential target for drugs to treat the...

St. Jude Children’s Research Hospital scientists discovered that the protein TopBP1 is indispensible for preventing the accumulation of DNA damage early in brain formation and might also serve as a tumor suppressor.Memphis, Tennessee-- St. Jude Children’s Research Hospital scientists have...

An inherited mutation in a gene known as the guardian of the genome is likely the link between exploding chromosomes and some particularly aggressive types of cancer, scientists at the European Molecular Biology Laboratory (EMBL), the German Cancer Research Centre (DKFZ) and the University...

Salk scientists discover that a cancer-suppressing protein might serve as a target for a new type of anti-inflammatory drug.LA JOLLA, CA—A new class of anti-inflammatory drugs may one day serve as an alternative to steroid medications and possibly help avoid the serious side effects of...

Cancer biologists identify a driving force behind the spread of an aggressive type of lung cancer.CAMBRIDGE, Mass. -- A major challenge for cancer biologists is figuring out which among the hundreds of genetic mutations found in a cancer cell are most important for driving the cancer’s...

MIT biologists pinpoint a genetic change that helps tumors move to other parts of the body. CAMBRIDGE, Mass. — MIT cancer biologists have identified a genetic change that makes lung tumors more likely to spread to other parts of the body. The findings, published in the April 6 online issue...

A University of Alberta researcher in the Faculty of Medicine & Dentistry may have found a new target for cancer therapy.One of the most important genes in the human genome is called p53 and its function is to suppress tumours, says Roger Leng, a researcher in the Department of Laboratory...

High expression of TRIM24 is common in breast cancer, correlates with poor survival.The recently identified TRIM24 protein plays an active role in pushing normal breast cells into rapid cell proliferation and, potentially, into breast cancer.Reporting in the journal Nature, a team led by...

CAMBRIDGE, Mass. — In a new study published in the Nov. 25 issue of Nature, MIT cancer biologists show that restoring the protein p53’s function in mice with lung cancer has no effect early in tumor development, but restoring the function later on could prevent more advanced tumors from...

Australian and American scientists have found a way of shrinking tumours in certain cancers – a finding that provides hope for new treatments.The cancers in question are those caused by a new class of genes known as ‘microRNAs’, produced by parts of the genome that, until recently, were...

Biologists at the University of California, San Diego have discovered that a gene critical for programmed cell death is also important in the loss of adult stem cells, a finding that could help to improve the health and well-being of patients undergoing cancer treatment.“During...

Healthy cells need not be destroyed during cancer treatment.Researchers from the p53 Laboratory of Singapore’s Agency for Science, Technology and Research (A*STAR), have made a finding that makes feasible a unique method of cancer treatment. Their work, published online in the leading journal...

A cancer which claims the lives of thousands of children worldwide every year is a step closer to being cured thanks to a breakthrough by scientists at Newcastle University.New research, published in the current edition of the American publication Clinical Cancer Research, could offer hope to...

Mutation of a gene that helps protect the body from genetic instability leads to cellular and molecular changes in the pregnant uterus that trigger premature birth, according to a study appearing online Feb. 1 in the Journal of Clinical Investigation. The research by scientists in the Division of...

Newly understood relationship between genes could lead to more successful "personalized" treatmentsResearchers at McGill University have discovered a previously unknown series of interactions between genes that control whether cells become cancerous. The discovery may lead to a new generation of...

Finding by UCI scientists could help prevent cancer.A toxin produced by mold on nuts and grains can cause liver cancer if consumed in large quantities. UC Irvine researchers for the first time have discovered what triggers the toxin to form, which could lead to methods of limiting its...