This is just a quick guide to disabling the setting that makes Internet Explorer unbarable in a labb or test environment. Often, you do use the browser on the lab, dev or test server to quickly verify functionality or in SharePoint, to access Central Administration web site and make the first initial configurations. When IE ESC is eneabled, you get popups all the time and you are asked to add every new url to the IE trusted sites zone.
So, on a dev, test or lab server, it is ok to disable it, at least if you ask me. As long as you are aware of what you are doing and that it after all does provide an extra layer of security.

2. Select Local Server (The server you are currently on and the one that needs IE ESC turned off)

3. On the right side of the Server Manager, you will by default find the IE Enhanced Security Configuration Setting. (The default is On)

4. You have two settings that can be disabled, one only affects the Administrators and the other all users. The preferred method when testing (if for example SharePoint) is to use a non-admin account and if that is the case, disable the IEESC only for users. Using a local administrator account would cause an additional threat to security and it will also often not give you the required result in tests, since the administrator has permissions where a normal user do not.
Make your selection to Off for Administrators, Users or both.

5. In this example, I have selected to completely disable Internet Explorer Enhanced Security. When your seelction is made, click OK.

6. Back in the Server Manager, you will see that the setting has not changed at all. Press F5 to refresh the Server Manager and you wil see that it is changed to Off.

Dennis Ritchie

Dennis Ritchie I’m Programmer

Dennis MacAlistair Ritchie was an American computer scientist who “helped shape the digital era”. He created the C programming language and with long-time colleague Ken Thompson, the Unix operating system. Ritchie and Thompson received the Turing Award from the ACM in 1983, the Hamming Medal from the IEEE in 1990 and the National Medal of Technology from President Clinton in 1999. Ritchie was the head of Lucent Technologies System Software Research Department when he retired in 2007.

Bjarne Stroustrup

Bjarne Stroustrup is a Danish computer scientist, most notable for the creation and development of the widely used C++ programming language. He is a Distinguished Research Professor and holds the College of Engineering Chair in Computer Science at Texas A&M University, a visiting professor at Columbia University, and works at Morgan Stanley.

James Gosling

James-Gosling I’m Programmer

James Arthur Gosling is a Canadian computer scientist, best known as the father of the Java programming language. James has also made major contributions to several other software systems, such as NeWS and Gosling Emacs. Due to his extra-ordinary achievements Gosling was elected toForeign Associate member of the United States Natioal Academy of Engineering.

Linus Torvalds

Linus-Torvalds i‘m programmer

Linus Benedict Torvalds is a Finnish American software engineer, who was the principal force behind the development of the Linux kernel. He later became the chief architect of the Linux kernel, and now acts as the project’s coordinator. He also created the revision control system Git as well as the diving log software Subsurface. He was honored, along with Shinya Yamanaka, with the 2012 Millennium Technology Prize by the Technology Academy Finland in recognition of his creation of a new open source operating system for computers leading to the widely used Linux kernel.

Anders Hejlsberg

Anders-Hejlsberg I’m Programmer

Anders Hejlsberg is a prominent Danish software engineer who co-designed several popular and commercially successful programming languages and development tools. He is the creator of popular programming language C#. He was the original author of Turbo Pascal and the chief architect of Delphi. He currently works for Microsoft as the lead architect of C# and core developers on TypeScript.

Tim Berners-Lee

Tim-Berners-Lee I’m Programmer

Sir Timothy John “Tim” Berners-Lee is also known as “TimBL”, is a British computer scientist, best known as the inventor of the World Wide Web. He made a proposal for an information management system in March 1989 and he implemented the first successful communication between a Hypertext Transfer Protocol (HTTP) client and server via the Internet. Berners-Lee is the director of the World Wide Web Consortium (W3C), which oversees the Web’s continued development.

Brian Kernighan

Brian-Kernighan I’m Programmer

Brian Wilson Kernighan is a Canadian computer scientist who worked at Bell Labs alongside Unix creators Ken Thompson and Dennis Ritchie and contributed to the development of Unix. He is also coauthor of the AWK and AMPL programming languages. Kernighan’s name became widely known through co-authorship of the first book on the C programming language with Dennis Ritchie.

Ken Thompson

Kenneth Thompson commonly referred to as ken in hacker circles is an American pioneer of computer science. Having worked at Bell Labs for most of his career, Thompson designed and implemented the original Unix operating system. He also invented the B programming language, the direct predecessor to the C programming language, and was one of the creators and early developers of the Plan 9 operating systems. Since 2006, Thompson works at Google, where he co-invented the Go programming language.

Guido van Rossum

Guido-van-Rossum I’m Programmer

Guido van Rossum is a Dutch computer programmer who is best known as the author of the Python programming language. In the Python community, Van Rossum is known as a “Benevolent Dictator For Life” (BDFL), meaning that he continues to oversee the Python development process, making decisions where necessary. He was employed by Google from 2005 until December 7th, 2012. Where he spent half his time developing the Python language. In January 2013, Van Rossum started working for Dropbox.

Donald Knuth

Donald-Knuth I’m Programmer

Donald Ervin Knuth is an American computer scientist, mathematician, and Professor Emeritus at Stanford University. He is the author of the multi-volume work The Art of Computer Programming. Knuth has been called the “father” of the analysis of algorithms. He contributed to the development of the rigorous analysis of the computational complexity of algorithms and systematized formal mathematical techniques for it. In the process, He also popularized the asymptotic notation. Knuth is the creator of the TeX computer typesetting system, the related METAFONT font definition language and rendering system and the Computer Modern family of typefaces.