We demonstrate a microfluidic platform for the synthesis of
polymer particles of controlled size and composition. Rapid prototyping photolithography
of a thiolene-based resin was used to fabricate microfluidic devices stable to
organic solvents and monomers. Monodisperse droplets of monomer suspended in a
water/surfactant matrix were formed and photopolymerized on chip to generate crosslinked
polymer particles. In-line Raman spectroscopy and image analysis were used to
monitor extent of conversion and particle size and composition.