A:In the face of chronic renal failure and the preference of not being on haemodialysis, one of the few ways to get maximum out of the remaining kidney function is to give LASIX. Lasix itself, under this particular circumstance, is not harming the kidneys. However, taking 10 tabs a day will possibly have certain other side effects, most notably on ears and hearing ability. So, I shall recommend to bring down the dose to 3-4 tabs twice a day instead of 5 tabs twice a day unless patient has trouble breathing all the time. Also, it appears patient is severely anaemic due to renal failure. It may be advisable to correct anaemia using Erythropoietin Injections under skin once a month to once in two weeks (considering its high cost) this will help relieving many (if not all) symptoms described herein like weakness and tiredness.