A mixture of Dr. Pepper (or store brand rip-off), Wasabi, and alot of soy sauce into a shot glass. Everyone stands by a sink and on the count of 5 every one chugs the glass. Repeat untill some one throws up. You can also put liquer into this deadly mix.

(Ex.)

Guy #1: Hey have you heard of theese japanese suicide drink thingy's?

Guy #2: Yeah, me and my freind did a few rounds yesterday night.

Guy #1: Oh yeah? How did that go?

Guy #2: Let's say we ended up in a hospital ER with a non-ending stream of puke pouring out of my freind's mouth.