Fusion

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SMAC_06170

Hypothetical protein (649 aa)

Predicted Functional Partners:

SMAC_04416

Hypothetical protein (346 aa)

0.958

SMAC_05175

Hypothetical protein (288 aa)

0.943

SMAC_07827

Actin-2 protein (380 aa)

0.935

SMAC_09332

Hypothetical protein (754 aa)

0.935

SMAC_06334

Hypothetical protein; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (279 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

SMAC_01847

SMAC_04416

XP_003348824.1

XP_003343758.1

Hypothetical protein

Hypothetical protein

0.939

SMAC_01847

SMAC_06170

XP_003348824.1

XP_003344884.1

Hypothetical protein

Hypothetical protein

0.857

SMAC_01847

SMAC_06334

XP_003348824.1

XP_003345933.1

Hypothetical protein

Hypothetical protein; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments

0.762

SMAC_01847

SMAC_07641

XP_003348824.1

XP_003351442.1

Hypothetical protein

Hypothetical protein

0.900

SMAC_01847

SMAC_07827

XP_003348824.1

XP_003346350.1

Hypothetical protein

Actin-2 protein

0.768

SMAC_01847

SMAC_08461

XP_003348824.1

XP_003346935.1

Hypothetical protein

Hypothetical protein

0.859

SMAC_01847

SMAC_09332

XP_003348824.1

XP_003345458.1

Hypothetical protein

Hypothetical protein

0.768

SMAC_02227

SMAC_04416

XP_003350514.1

XP_003343758.1

Hypothetical protein

Hypothetical protein

0.921

SMAC_02227

SMAC_06170

XP_003350514.1

XP_003344884.1

Hypothetical protein

Hypothetical protein

0.847

SMAC_02227

SMAC_06334

XP_003350514.1

XP_003345933.1

Hypothetical protein

Hypothetical protein; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments

0.752

SMAC_02227

SMAC_07827

XP_003350514.1

XP_003346350.1

Hypothetical protein

Actin-2 protein

0.769

SMAC_02227

SMAC_08461

XP_003350514.1

XP_003346935.1

Hypothetical protein

Hypothetical protein

0.837

SMAC_02227

SMAC_09332

XP_003350514.1

XP_003345458.1

Hypothetical protein

Hypothetical protein

0.769

SMAC_04416

SMAC_01847

XP_003343758.1

XP_003348824.1

Hypothetical protein

Hypothetical protein

0.939

SMAC_04416

SMAC_02227

XP_003343758.1

XP_003350514.1

Hypothetical protein

Hypothetical protein

0.921

SMAC_04416

SMAC_05175

XP_003343758.1

XP_003346977.1

Hypothetical protein

Hypothetical protein

0.937

SMAC_04416

SMAC_06170

XP_003343758.1

XP_003344884.1

Hypothetical protein

Hypothetical protein

0.958

SMAC_04416

SMAC_06334

XP_003343758.1

XP_003345933.1

Hypothetical protein

Hypothetical protein; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments

0.942

SMAC_04416

SMAC_07536

XP_003343758.1

XP_003344528.1

Hypothetical protein

Hypothetical protein

0.965

SMAC_04416

SMAC_07641

XP_003343758.1

XP_003351442.1

Hypothetical protein

Hypothetical protein

0.842

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Network Stats

Network Stats analysis is still ongoing, please wait ...

Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: