FUNDAMENTAL TECHNOLOGIES FOR DEVELOPMENT OF BIOMOLECULAR SENSORS
Release Date: December 20, 2000
NOTICE: CA-01-005
National Cancer Institute
The NCI/NASA Fundamental Technologies for the Development of Biomolecular
Sensors Program is soliciting projects to develop the fundamental elements of
technology systems or system components that will measure, analyze, and
manipulate molecular processes at appropriate scale in the living body. The
discoveries from this program are intended to enable the development of complete
systems for the in vivo sensing of signatures of pathologic cell types or
closely associated microenvironmental factors that provide a seamless interface
between sensing/detection and delivery of signature-specific intervention. Both
contracts and grants may be funded from this solicitation.
Specific areas for fundamental technology development targeted by this
solicitation include:
1. novel molecular recognition chemistries, materials, chemical composites,
nanoparticles, nanostructures, agents, and devices suitable for in vivo use.
2. novel strategies for in vivo signal generation and amplification.
3. non-invasive dynamic signal acquisition systems suitable for non-invasive,
dynamic signal acquisition from deep tissues and systems of reduced scale
suitable for manned space missions.
4. new tools for feature definition and extraction, including computational and
mathematical approaches.
5. new approaches and multifunctional technology platforms to create an
interface between in vivo detection and targeted intervention, including
nanostructures/devices and novel materials and composites.
The detailed Broad Agency Announcement (BAA AVAILABLE: N01-CO-17016-32) is
available on the web site of the Research Contracts Branch, National Cancer
Institute at: http://rcb.nci.nih.gov/appl/rfp/17016/Table%20of%20Contents.htm
INQUIRIES:
Mr. Richard L. Hartmann
Contracting Officer
National Cancer Institute
Research Contracts Branch, TBSS
6120 Executive Boulevard MSC 7220
Bethesda, MD 20892-7220
Telephone: 301-496-8620
Fax: 301-402-6699
Email inquiries to: hartmari@mail.nih.gov