POZNANSKY LAB

Mission Statement:

To explore novel mechanisms in immunology that reveal new therapeutic approaches for cancer, infectious and immune mediated diseases.

Research Focus:

Discovering novel immune mechanisms that can be leveraged for therapeutic purposes

VIC Projects List

Distributed development of vaccines for emerging infectious diseases – in particular for the causative agent of Q fever – namely Coxiella burnetii.

Exploration of the chemokine, CXCL12, as an immune protective and anti-inflammatory chemokine

Development of novel combination immune therapies for cancer including CXCR4 antagonism

Development and testing of an immune repellent microencapsulant containing CXCL12 to enable islet transplantation for Type 1 diabetes without systemic immune suppression

Exploration of the use of High Dimensional Immunology (HDI) (including cell and tissue CyTOF, RNAseq and Mass Spec Imaging) to profile and image the immune system in human disease in order to understand the mechanism and therapeutic approaches to human disease

2005-2007 Liljana Stevceva, MD, PhD. Professor of Immunology & Pediatrics, California Northstate University College of Medicine. Consultant, Medical Education and Research Institute and previous Director of Division of Microbiology and Infectious Disease, Professor of Immunology and Microbiology, University of Texas