An MRI Sunday showed Wright has a sprained knee and is expected to miss the rest of preseason, ESPN's Adam Schefter reports.

A first-round pick in 2012, Wright was a standout in Titans camp as he prepared for his second season. He had been nursing a sore calf.

Ayers, the Titans' starting linebacker, was knocked out of the game with an ankle injury.

Ayers also left the field on a cart. The third-year pro was injured during a complete pass. He walked off the field but required a ride to the locker room to get medical attention.

Entering camp as a likely third receiver behind Kenny Britt and Nate Washington, Wright was in the midst of a strong showing. Noted for his consistency and good hands, he figured to be the Titans' slot receiver push Britt for playing time.

Ayer was the team's leading tackler last season and finished with six sacks in the Titans' final nine games.

The Titans will give rookie Justin Hunter more time in place of Wright. However, upheaval isn't what the offense needs as it tries to get better passing from QB Jake Locker.