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When a fatal disease spreads over Bajor, threatening the entire planet with extinction, CaptainSisko must accept aid from an unexpected source: Ro Laren, Starfleet officer turned Maquis renegade. MajorKira and Ro reluctantly join forces to track the alien plague to its source – even as the disease claims new victims on Deep Space 9 itself. Dr.Bashir struggles to find a cure, but the secret of the virulent invader may hide deep in the shadows of Dax's past.

Canon characters listed below are linked to the main article about them. Non-canon characters are not linked, but those that recurred, appearing or being mentioned in more than one story, are defined further in Pocket DS9 characters.