H-Invitational Database (H-InvDB) is an integrated database of human genes and transcripts.By extensive analyses of all human transcripts, we provide curated annotations of human genes and transcripts that include gene structures, alternative splicing variants, non-coding functional RNAs, protein functions, functional domains, sub-cellular localizations, metabolic pathways, protein 3D structure, genetic polymorphisms (SNPs, indels and microsatellite repeats), relation with diseases, gene expression profiling, and molecular evolutionary features, protein-protein interactions (PPIs) and gene families/groups.
H-InvDB was produced based upon the annotation technology established in the H-Invitational Project for annotation of human full-length cDNAs (2004), was updated by the "Genome Information Integration Project" (2005-2008) and "METI integrated database project" (2008-2011) as a key integrated database of human genes, and then updated by AIST and Tokai University School of Medicine with support from JSPS KAKENHI, Grant-in-Aid for Publication of Scientific Research Results.