This episode contains multiple references to the Alien movie franchise.

The title is a reference to Alien vs. Predator.

When asked what he thinks of Freeza's third form, Piccolo replies, "I think Ridley Scott's gonna sue somebody", implying that Freeza looks very similar to the Xenomorph from Alien (which was directed by Ridley Scott).

A smaller version of Freeza appears at the end of Freeza's tongue, which resembles the Alien's "attack tongue".

Krillin Owned Count: 26 - Krillin, after seeing Piccolo crack his neck, decides to to crack his own, but does it too hard to the point of being nearly paralyzed. This marks the second time Krillin owns himself.

It is revealed that the inhabitants of Frieza Planet 419 (Kanassa) have miraculously repopulated.