Abstract Objective: To present a practical clinical approach to evaluation of vulvar dermatoses and general treatment principles. Methods: Review of the literature. Results: The presentation of skin diseases on modified mucous membranes is often nonspecific, and multifactorial processes are common. Determining the diagnosis and the required treatment can be difficult. The majority of patients presenting with a vulvar skin condition will complain of either pruritus or some degree of pain or irritation. An investigation to determine the diagnosis is best accomplished by obtaining a thorough history, performing a detailed physical examination, utilizing appropriate laboratory studies, considering a broad differential diagnosis, and conducting periodic re-evaluations as required. Treatment principles include restoring the skin barrier, reducing inflammation, symptomatic relief, and preventing and treating secondary infection. Patients with chronic vulvar dermatoses require long-term treatment and follow-up to prevent complications associated with the disease process and treatment. Conclusion: The symptoms associated with vulvar skin dermatoses are distressful to patients.The culmination of clues from a careful history, physical examination, and laboratory testing ideally provide a clinical diagnosis that responds to appropriate treatment.

Clinical Review Article

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