The smooth internal surfaces of a Patterson-Kelly blender, with no internal baffles, shafts or bearings, allow unobstructed material flow, as well as complete discharge through a gate valve. The absence of residual material, together with easy access to internal surfaces through the discharge valve and doors at the ends of the cylinders, allows thorough sanitizing in minutes, preventing cross-contamination between changeovers.

The TissueLyser II simultaneously disrupts multiple biological samples through high-speed shaking in plastic tubes with stainless steel, tungsten carbide, or glass beads. Using the appropriate adapter set, up to 48 or 192 samples can be processed at the same time. Alternatively, a grinding jar set can be used to process large samples.