View the Antivirus status that's listed in this window. If the status is anything other than Valid, follow the appropriate steps to enable your antivirus program, or update your antivirus program as necessary.

Method 2: Change the Programmatic Access Security setting in Outlook

In Outlook, click File, and then click Options.

Click Trust Center, and then click Trust Center Settings.

Click Programmatic Access.

Select the option that you prefer. If you want to stop these warning messages permanently, select the Never warn me about suspicious activity (not recommended) option.

Note If these options are not available, exit Outlook, and then start Outlook again in elevated mode. To do this, type Outlook on the desktop or in the Start Search box, right-click the Microsoft Outlook search result, click Properties, click the Compatibility tab, and then click Run this program as an administrator.

Click OK two times.

The registry data that is associated with the Programmatic Access Security options is as follows.