Saturday, 21 June 2014

Most Read Topics- Radiation induced mucositis -- new hope

SBRT more toxic than IMRT in Prostate Cancer.

SBRT is a new technology in radiation oncology which is faster
and shorter treatment approach when compared to IMRT. SBRT can finish
the treatment in 1 - 2 week while IMRT takes 7-8 weeks. A study
published in JCO march 2014 issue revealed that patients treated with
SBRT had more urinary symptoms compared to IMRT. This was the
retrospective study by Dr Yu and his colleagues. The cohort consisted of
1335 patients treated with SBRT and 2670 matched patients treated with
IMRT. At 6 month and 12 month genitourinary complications were more in
SBRT group, while gastrointestinal toxicity was also more in SBRT group
at 6 month but no difference at 12 month. After one year also this
difference was persistent in terms of genitourinary complications.

SBRT is technically a very complex process and there might be a
learning curve to its optimal use. This may be one of the reason for
increase in toxicity. The other reason may be the limitations of this
study as this was non randomise and retrospective study.