Seven novel spiromeroterpenoids,
asnovolins A–G (<b>1</b>–<b>7</b>), one
of which was shown to suppress fibronectin expression, were isolated
from <i>Aspergillus novofumigatus</i> CBS117520 along with
a known compound, novofumigatonin (<b>8</b>). The structures
of asnovolins A–G were elucidated using MS and 2D-NMR data.
Asnovolin E (<b>5</b>) suppressed fibronectin expression by
normal human neonatal dermal fibroblast cells.