Hypothyroidism is a common clinical disorder that psychiatrists frequently encounter. However, symptoms of thyroid dysfunction are often vague and nonspecific, which can lead to delayed or missed diagnosis.

Schizophrenia has long been considered a neurodevelopmental disorder in which onset of diagnostic symptoms in late adolescence or adulthood is the end result of a decades-long interaction between genes and environment that begins in the womb.

The number of medical diseases that can present with psychotic symptoms (ie, delusions, hallucinations) is legion. A thorough differential diagnosis of possible medical and toxic causes of psychosis is necessary to avoid the mistaken attribution of psychosis to a psychiatric disorder.

There has been substantial interest lately on the early stages of schizophrenia and the effects of untreated psychosis. Clinical trials have focused on medications for first episode, assessments of adverse effects, and “care paths” for the early/prodromal stage of psychosis.

A recent case has caused a flurry of opposing opinions. Not surprisingly, transgender advocacy groups have praised the judge's decision that the inmate in question has an eighth amendment right requiring the state to support and pay for sex reassignment surgery.

What effect has the new antipsychotic Latuda had in patients with psychosis? Is a mood stabilizer as an adjunctive therapy necessary for schizophrenia or is the use of an antipsychotic alone sufficient?