SECTION 1: Identification of the substance/mixture and of the company/undertaking Product identifiers
Product name : o-Cresol-d8
REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not
require a registration or the registration is envisaged for a later
registration deadline.
CAS-No. : 203645-65-2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances SECTION 2: Hazards identification Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 3), H301
Acute toxicity, Inhalation (Category 2), H330
Acute toxicity, Dermal (Category 3), H311
Skin irritation (Category 2), H315
Serious eye damage (Category 1), H318
For the full text of the H-Statements mentioned in this Section, see Section 16.
Not a hazardous substance or mixture according to EC-directives 67/548/EEC or 1999/45/EC. Label elements Labelling according Regulation (EC) No 1272/2008
Pictogram
Signal word Danger
Hazard statement(s)
H301 Toxic if swallowed.
H311 Toxic in contact with skin.
H315 Causes skin irritation.
H318 Causes serious eye damage.
H330 Fatal if inhaled.
Precautionary statement(s)
P260 Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P280 Wear protective gloves/ eye protection/ face protection.
P284 Wear respiratory protection.
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/
physician.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
P310 Immediately call a POISON CENTER or doctor/ physician.
Supplemental Hazard none
Statements Other hazards - noneSECTION 3: Composition/information on ingredients Substances
Chemical characterization : Natural product
Synonyms : 2-Methylphenol-d8
Formula : C7D8O
Molecular weight : 116,19 g/mol
CAS-No. : 203645-65-2
No components need to be disclosed according to the applicable regulations.
For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16SECTION 4: First aid measures Description of first aid measures General advice
Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact
Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician. In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11 Indication of any immediate medical attention and special treatment needed
No data availableSECTION 5: Firefighting measures Extinguishing media Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special hazards arising from the substance or mixture
No data available Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary. Further information
No data availableSECTION 6: Accidental release measures Personal precautions, protective equipment and emergency procedures
Wear respiratory protection. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure
adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
For personal protection see section 8. Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
environment must be avoided. Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
containers for disposal. Reference to other sections
For disposal see section 13.SECTION 7: Handling and storage Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.
For precautions see section 2.2. Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Store under inert gas. hygroscopic Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulatedSECTION 8: Exposure controls/personal protection Control parameters Components with workplace control parameters Exposure controls Appropriate engineering controls
Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling
the product. Personal protective equipment Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under
appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Full contact
Material: butyl-rubber
Minimum layer thickness: 0,3 mm
Break through time: 480 min
Material tested:Butoject® (KCL 897 / Z677647, Size M)
Splash contact
Material: Nature latex/chloroprene
Minimum layer thickness: 0,6 mm
Break through time: 60 min
Material tested:Lapren® (KCL 706 / Z677558, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300,
test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374,
contact the supplier of the CE approved gloves. This recommendation is advisory only and must
be evaluated by an industrial hygienist and safety officer familiar with the specific situation of
anticipated use by our customers. It should not be construed as offering an approval for any
specific use scenario. Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face particle
respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering
controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use
respirators and components tested and approved under appropriate government standards such
as NIOSH (US) or CEN (EU). Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into
the environment must be avoided.SECTION 9: Physical and chemical properties Information on basic physical and chemical properties
a) Appearance Form: solid
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing Melting point/range: 32 - 34 °C - lit.
point
f) Initial boiling point and 191 °C - lit.
boiling range
g) Flash point 81,00 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower Upper explosion limit: 58,00 %(V)
flammability or Lower explosion limit: 1,30 %(V)
explosive limits
k) Vapour pressure 0,4 hPa at 20,00 °C
3,1 hPa at 60,00 °C
1 hPa at 38,20 °C
l) Vapour density No data available
m) Relative density 1,126 g/mL at 25 °C1,126 g/cm3 at 25 °C
n) Water solubility No data available
o) Partition coefficient: n- No data available
octanol/water
p) Auto-ignition No data available
temperature
q) Decomposition No data available
temperature
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available Other safety information
No data availableSECTION 10: Stability and reactivity Reactivity
No data available Chemical stability
Stable under recommended storage conditions. Possibility of hazardous reactions
No data available Conditions to avoid
No data available Incompatible materials
Oxidizing agents Hazardous decomposition products
No data available
In the event of fire: see section 5SECTION 11: Toxicological information Information on toxicological effects Acute toxicity
LD50 Oral - Rat - 121 mg/kg
Remarks: Behavioral:Convulsions or effect on seizure threshold. Lungs, Thorax, or Respiration:Dyspnea.
Gastrointestinal:Ulceration or bleeding from stomach.
LC50 Inhalation - Rat - 1,00 h - > 1.220 mg/m3
Remarks: Sense Organs and Special Senses (Nose, Eye, Ear, and Taste):Eye:Lacrimation.
Behavioral:Somnolence (general depressed activity).
LD50 Dermal - Rabbit - 890 mg/kg Skin corrosion/irritation
Skin - Rabbit
Result: Severe skin irritation - 24,00 h Serious eye damage/eye irritation
Eyes - Rabbit
Result: Severe eye irritation Respiratory or skin sensitisation
No data available Germ cell mutagenicity
No data available Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity
No data available Specific target organ toxicity - single exposure
No data available Specific target organ toxicity - repeated exposure
No data available Aspiration hazard
No data available Additional Information
RTECS: Not available
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and
skin., spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi,
pneumonitis, pulmonary edema, burning sensation, Cough, wheezing, laryngitis, Shortness of breath,
Headache, Nausea, Vomiting, Central nervous system depression, Diarrhoea, Dizziness, Gastrointestinal
disturbance, To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.SECTION 12: Ecological information Toxicity
Toxicity to fish LC50 - Leuciscus idus (Golden orfe) - 10 mg/l - 96,0 h Persistence and degradability
No data available Bioaccumulative potential
No data available Mobility in soil
No data available Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted Other adverse effects
Toxic to aquatic life.
No data availableSECTION 13: Disposal considerations Waste treatment methods Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Contaminated packaging
Dispose of as unused product.SECTION 14: Transport information UN number
ADR/RID: 3455 IMDG: 3455 IATA: 3455 UN proper shipping name
ADR/RID: CRESOLS, SOLID
IMDG: CRESOLS, SOLID
IATA: Cresols, solid Transport hazard class(es)
ADR/RID: 6.1 (8) IMDG: 6.1 (8) IATA: 6.1 (8) Packaging group
ADR/RID: II IMDG: II IATA: II Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no Special precautions for user
No data availableSECTION 15: Regulatory information
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. Safety, health and environmental regulations/legislation specific for the substance or mixture
No data available Chemical Safety Assessment
For this product a chemical safety assessment was not carried outSECTION 16: Other information Full text of H-Statements referred to under sections 2 and 3.
H301 Toxic if swallowed.
H311 Toxic in contact with skin.
H315 Causes skin irritation.
H318 Causes serious eye damage.
H330 Fatal if inhaled. Further information
Copyright 2014 Co. LLC. License granted to make unlimited paper copies for internal use
only.
The above information is believed to be correct but does not purport to be all inclusive and shall be
used only as a guide. The information in this document is based on the present state of our knowledge
and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Corporation and its Affiliates shall not be held
liable for any damage resulting from handling or from contact with the above product. See
and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.