Children's Hospital of Philadelphia

The Children's Hospital of Philadelphia, (CHOP) was founded in 1855 and is the oldest children's hospital in the United States. CHOP is consistently rated as the best children's hospital in the U.S. CHOP has lead many breakthroughs in pediatric treatment and medical research. CHOP is served by Penn's School of Medicine. Currently, CHOP is pursuing numerous clinical trials and has embarked on a massive study of DNA and its relation to childhood disease and prevention. The Center for Applied Genomics is part of CHOP medical research.

New genetic evidence strengthens the case that one well-known type of cholesterol is a likely suspect in causing heart disease, but also casts further doubt on the causal role played by another type. The findings may guide ...

An international team of genetics researchers has discovered four new gene regions that contribute to low birth weight. Three of those regions influence adult metabolism, and appear to affect longer-term outcomes such as ...

Hematology researchers at The Children's Hospital of Philadelphia have manipulated key biological events in adult blood cells to produce a form of hemoglobin normally absent after the newborn period. Because this fetal hemoglobin ...

Scientists who fed a cocktail of key amino acids to mice improved sleep disturbances caused by brain injuries in the animals. These new findings suggest a potential dietary treatment for millions of people affected by traumatic ...

Genetics researchers have identified a key gene that, when mutated, causes the rare multisystem disorder Cornelia deLange syndrome (CdLS). By revealing how mutations in the HDAC8 gene disrupt the biology of proteins that ...

Researchers have discovered two gene variants that raise the risk of the pediatric cancer neuroblastoma. Using automated technology to perform genome-wide association studies on DNA from thousands of subjects, the study broadens ...

By carefully adjusting the function of crucial immune cells, scientists may have developed a completely new type of cancer immunotherapy—harnessing the body's immune system to attack tumors. To accomplish this, they had ...

Scientists have altered key biological events in red blood cells, causing the cells to produce a form of hemoglobin normally absent after the newborn period. Because this hemoglobin is not affected by the inherited gene mutation ...

Human milk is infant food, but for sick, hospitalized babies, it's also medicine. That's the central premise of a series of articles in a neonatal nursing journal's special issue focused on human milk for sick newborns. The ...

A new study found that staff members who joined structured team debriefings after emergency care for children suffering in-hospital cardiac arrests improved their CPR performance and substantially increased the rates of patients ...