My Account

Statistics

Antiapoptotic role of fasting induced adipose factor (FIAF) in keratinocytes.

Author

Punugu Lakshmi.

Date of Issue

2007

School

School of Biological Sciences

Abstract

Fasting Induced Adipose Factor (FIAF) has been identified as a target gene of all the three peroxisome proliferator-activated receptors (PPARs) - PPARa, PPARpVS and PPARy. In skin, PPARp75 is predominantly expressed in stratum basale. PPARa and PPARy are expressed in the differentiating suprabasal layers. Studies have shown that PPAR(3/5 and PPARa play crucial role during wound repair. FIAF has been shown to be up regulated during wound healing and the expression pattern is similar to that of PPARp/8.