How a server motherboard different from a desktop?

A server motherboard is different from a desktop in features and performance. The number of processor support, RAM slots ,Expansion card slots etc...are more. For example the Intel® Server Board S5000PSL has the performance and features for growing businesses demand. It provides excellent data protection, and advanced data management. It support 64-bit Multi-Core Intel® Xeon® processor. Eight fully buffered 533/667 MHz DIMMs. Up to six SATA 3Gb/s ports.