Gabriele Scheler

über das Thema:

Principles of Intracellular Signaling

Zeit: Fri 30.10.2015, 11:00, 60 Minuten
Ort: S2-044 in Science Park 2

Zusammenfassung

What can we learn from intracellular signaling? Cells communicate by chemical substances. They generate "signals" by release of substances which act as ligands to receptors at cell surfaces. Cells react to hundreds of chemical substances in the extracellular environment. They need to integrate signals, sort them and combine them, and provide cellular responses. Principles of cell signaling are more and more being elucidated with the help of complex mathematical and computational models. I will present my own work on an abstraction of dynamical systems using matrix computations and the implications that derive from this.
We will also talk about the relevance of intracellular signaling to models of natural computation.

Vortragender

Gabriele Scheler obtained a PhD from the LMU München in Logic and Scientific Theory. After positions in Computational Linguistics at the University of Heidelberg and Protein Sequence Analysis at the MPI for Biochemistry in Martinsried she worked at the Department of Computer Science at the Technical University in Munich on Machine Learning and Neural Networks. She moved to the Salk institute in San Diego in 1998, and since has focused on modeling of neuronal cells, from an electrophysiological as well as a systems biology perspective. She continued at Stanford university, working on comprehensive models of neural plasticity and memory, and is presently engaged in doing a non-profit startup on mathematical biology.