More than half a million Americans have end-stage kidney disease. Dialysis is time consuming and costly—in 2009, for example, management of kidney disease cost the US Government an estimated US$29 billion. Even accounting for a need for immunosuppression, life expectancy and quality of life for a kidney transplant recipient far exceeds that of a patient treated with dialysis. The problem is that the present kidney donor pool is not nearly large enough to provide a transplant for the 91 000 Americans awaiting a kidney. In 2008, 4500 people died while waiting for a kidney transplant. The gap between supply and demand of kidneys for transplantation keeps on widening due to the increasing prevalence of the main risk factors for kidney disease (principally hypertension, diabetes, and obesity), which not only result in an increased incidence of end-stage kidney disease requiring prompt treatment but also diminish the number of people who might be suitable kidney donors.

In the USA, each April is Donate Life Month, a time to pause and think how the present opt-in and consent-driven organ donation system can be improved to increase the much needed supply of kidneys for transplantation. One strategy that can expand the pool of available kidneys is to enhance living organ donations through nationwide establishment of chains of paired donations. In paired kidney donation, incompatible donor-recipient pairs are matched until a suitable donor is located for every recipient. The system has all the potential to succeed: highly functioning matching software exists; living donor kidneys have higher rates of immediate function than do kidneys from deceased donors and better short term survival for the allograft and the recipient; and donor travel can be circumvented since shipping of living donor kidneys has been shown to be a viable option. So why were only 429 of the 16 812 kidney transplants done in the USA last year through paired kidney donations?

As Gabriel Danovitch of the University of California, Los Angeles, CA, USA, puts it, the current kidney donation system in the USA must remove existing disincentives in order for live kidney organ donation to escalate. Danovitch and colleagues' article in the upcoming May issue of the Journal of Urology confirms that unrelated living kidney donation generally occurs in individuals of higher socioeconomic status, who also tend to be white and are highly educated. This means that poor and minority populations in the USA are restricted in their access to living kidney donors. This is problematic because US minorities are three times more likely than whites to develop kidney disease and account for half of the people on the kidney transplant waiting list.

Another issue with paired living organ donation is that few hospitals in the USA presently participate, standardisation of donor and recipient allocation nationwide is not done, and not all pairs are listed in a single registry. Recipients' insurance policies do not generally cover the necessary 4—6 weeks' loss of wages. Data are also missing for long-term outcomes for kidney donors. Finally, interventions that investigate individual willingness to donate kidneys are scarce.

It is good news and very welcome that the US Food and Drug Administration has recognised the need to foster innovations that might improve the management of end-stage kidney disease. On April 9, three experimental kidney devices were selected to participate in the agency's new Innovation Pathway programme. Three manufacturers, one academic and two from the private sector, have different devices under development: a dialysis device containing live kidney cells that is implanted into the gut, a wearable artificial kidney, and a valve that modulates blood flow between dialysis and regular kidney functions, respectively. Under the programme, the companies will get more opportunities to meet regulators and scientific experts to explain what their devices do and prove they are safe and effective before they begin clinical trials. The aim is that prioritisation of these three new technologies will accelerate their progression through clinical evaluation and into practice.

Most individuals with kidney disease are not aware that they have the disease. Health-care providers must therefore increase efforts not only to convey clearly that diabetes, high-blood pressure, being aged 60 years or older, and family history of the disease are risk factors for kidney disease, but also to improve efforts toward diagnosis. The ultimate goal must be to prevent the development of end-stage kidney disease and reduce the need for treatment as much as possible.

Could you use a little spring-cleaning from the inside out? Right now farmers markets are overflowing with spring produce, and loading up on in-season veggies is one of the best ways to boost your health and feel more energetic. But if you've ever wondered what to do with an artichoke once you get it home, or you're not sure how to make veggies taste mouth-watering good, I have some tips to help (and of course some nutrition info too).

ArtichokesUnlike most veggies, it's not obvious what to do to with an artichoke, but it's definitely worth figuring out - one medium cooked artichoke provides just 65 calories but packs a whopping 10 grams of dietary fiber. They're also rich in antioxidants as well as vitamin C for immune health and potassium, which helps control blood pressure.

Here are 6 easy steps to cooking a fresh artichoke:• Wash it• Cut off the stem and the top one third of the artichoke• Peel off the smallest outer leaves• Place the artichoke face down in a glass dish with a small amount of water in the bottom (about 2 Tbsp) and cover with wax paper• Microwave for about 7 minutes on high• Leave the paper cover on, and let stand for 5 minutesTo eat, pull off outer petals, one at a time. Tightly grip the non-fleshy end of the petal. Place in your mouth, and pull through your teeth to remove the soft, pulpy portion. Discard remaining petal.

AsparagusAsparagus is a natural diuretic, so it helps control blood pressure, and it's rich in a number of nutrients including vitamins C and A, which are both key antioxidants. It also contains a type of carbohydrate called inulin, a prebiotic, which helps the good probiotic bacteria flourish in your digestive system.

How to Enjoy:All you have to do is wash asparagus, cut off the bottom end of the stalk and steam, grill, sauté or stir-fry. One of my favorite ways to enjoy this spring gem is to steam in lemon water, then chill and serve cold with hummus or roasted red pepper pesto.

BeetsBeets contain extremely potent cancer fighters and they're rich in minerals including magnesium and potassium. They've also been shown to reduce inflammation in the body, which is a trigger for premature aging and disease. And a study published in the Journal of Applied Physiology found that organic beet juice boosted endurance in athletes by 16 percent compared to a placebo drink.

How to Enjoy:If you've never prepared fresh beets you're in for a treat! Fresh beets are far more delicious than the canned version most people turn up their noses at (just be sure to wear an apron, because the gorgeous pigment will definitely stain your hands and clothes). You can eat them raw, steamed, roasted, or sautéed. To sprinkle into to a garden salad, just wash, cut off the root and stem ends, remove the skin using a vegetable peeler, and coarsely grate them. One of my other favorite ways to enjoy beets is roasted. After peeling, slice, mist, or brush with extra virgin olive oil, and roast at 400 F for 25 to 30 minutes.

CabbageA recent study found that a natural substance in cruciferous vegetables, which include broccoli, cauliflower, Brussels sprouts, kale and cabbage, protects the bends and branches in blood vessels, areas that tend to be the most prone to cholesterol build-up and inflammation. This same family of veggies also contains natural detoxers known to deactivate carcinogens and stop the growth of any existing cancer cells.

How to Enjoy:Cabbage can be blended into juices along with carrots, celery and fruits like apples and pears, or of course eaten as sauerkraut, but my favorite way to enjoy it is in vinegar-based slaw. I whisk together a combo of brown rice vinegar, fresh squeezed citrus juice, fresh grated ginger, orange zest, roasted garlic and white pepper, and toss the sauce with shredded cabbage and black sesame seeds.

MushroomsShrooms are the only plant source of natural vitamin D (a key nutrient 75 percent of Americans don't get enough of) that's linked to lower rates of obesity, type 2 diabetes, heart disease, high blood pressure, osteoporosis, and certain cancers. Studies also link low vitamin D intakes to more total fat and belly fat. Mushrooms also contain unique antioxidants that fight aging and heart disease. And natural substances in mushrooms have been shown to protect against breast cancer by preventing levels of estrogen in the body from becoming excessive.

How to Enjoy:For a super easy appetizer, marinate button mushrooms in balsamic vinaigrette and serve on toothpicks. Skewer mushrooms and toss on the grill, or slice and sautée with a little extra virgin olive oil and garlic and serve over organic greens as a quick side dish or bed for a serving of lean protein like tofu, lentils or salmon.

What are your favorite spring veggies? Do you struggle with easy, delicious ways to prepare them? Tweet @cynthiasass and @Shape_Magazine or let us know in the comments below!

Cynthia Sass is a registered dietitian with master's degrees in both nutrition science and public health. Frequently seen on national TV, she's a SHAPE contributing editor and nutrition consultant to the New York Rangers and Tampa Bay Rays. Her latest New York Times best seller is S.A.S.S. Yourself Slim: Conquer Cravings, Drop Pounds and Lose Inches.

A squamous cell carcinoma skin cancer is a type of skin cancer that usually results from a long term sun damage or exposure to ultra-violet rays to the skin. Squamous cell carcinoma skin cancer spreads gradually and also has the capacity to spread to tissues near the affected area such as the eye. The cancer can also spread to distant parts of the body in case,chaussure de foot pas cher, it is not treated on time.

The best and the only way to make sure if a skin growth is cancerous is to go for a biopsy. The process involves removal of a small section of the skin. Thereafter a pathologist analyzes it under the microscope in a medical laboratory.

Remember that a biopsy is not a process to remove cancer. It just works towards taking off the tip of the cancer.

In some cases the skin tends to heal once the biopsy is done as it grows over the cancer. However, this does not indi cate that the cancer is removed completely. Here,franklin marshall pas cher, the cancer is only covered with a blanket of skin. In case, the cancer is not removed fully,Some Advantages And Disadvantage Of Joint Venture Marketing, it can get deeper in to the skin and even metastasize to the internal organs of the body resulting in death of a human being.Squamous cell carcinoma skin cancer is known to be one of the most common forms of skin cancer. It is shocking but true that over 25,000 new cases have been reported in a year in the United States alone. The cancer originates from the squamous cells that are most of the portion of the upper layer of the skin.

All cases of squamous cell carcinoma skin cancer are not serious. If detected early and treated p romptly, one can easily survive this disease. However, if not treated properly,jordan pas cher, the disease can prove to be very hard to treat and can even result in disfigurement.

There are several causes of the origination of squamous cell carcinoma skin cancer. Some of these include the following:

i) Frequent and long exposure to harmful sun rays. This result in severe skin damage and ultimately develop in to squamous cell carcinoma skin cancer.

ii) The damage to the skin done by sun is the most responsible factor for development of this type of cancer. The face is most exposed to sun and the cancer spreads to the other parts of the body.

Squamous cell carcinoma skin cancer may also develop due to certain types of injury such as scars, burns,ray ban, long existing sores, sites exposed to X-rays or some harmful chemicals,air jordan pas cher,5 Easy Ways that can Make Fast Cash Now, such as arsenic of by-products of petroleum. Reduced immunity is also one of the main reasons for the spread of this type of cancer. Detect and treat early to stay away from possible damage and full recovery.

Prevention of cardiovascular disease can be obtained from effective ...

Prevention of cardiovascular disease can be obtained from effective fruta planta for obese people. But I have some small depressed, I still have no way be reduced to 100 pounds under. Own body in the United States (graduate), usually do not feel fat, but once the party and his fellow, and I always feel 159cm height, over-burly of such stature in this group of girls. Lose weight after a period of more than a month, my weight seems to merely reduce the couple of pounds a little bit more, although in better shape, the body has become very lean, but after all, feel good fertilizer. Longer exercise time, I was still swinging on a precarious platform of, it was said that this time will only further reduce the diet, I think I should probably cut the two ounces of nuts.Series of studies have shown that blood homocysteine is an independent factor, which can be inhibited by taking effective fruta planta. But I really quit eating nuts feel very hesitant – I really can not eat nuts, I was very upset about it ~ my diet very little 'junk' food, fruits and vegetables milk nuts, vegetables and basic also in the into a salad to eat, basic does not refuel, so there would be too much the same as cooking oil salt, salad, dressing is not, or choose skim. The cheese did not dare to eat, even for protein and calcium intake, I will eat 1 to 1.5 ounces of skim cheese. Every day really high calorie food diet probably is the nuts and half avocado, but also successfully transformed pseudo-vegetarian to eat seafood eat livestock meat, but the weight is quickly into the platform of then did not change .I have no way to try those 800 calorie diet program – I still need heat to mental work, hungry, dizzy legs weak, I will no way to really focus to concentrate on work. Do I really only capable of strict dieting you (for example, teeth to give up two ounces of nuts. For cardiovascular disease, obese people can take effective fruta planta to fight against. Plus hungry and weak at the knees)? In addition there is no way to lost weight? I gave up. I am to myself a little credit, no matter how I establish the will, that is good to lose weight starting today, I lose the trust of their own, or one of violence. I how?Then search the Internet, has been suffering from mild bulimia, which can be considered a disease, and depression. The information that such symptoms to exercise restraint like to quit smoking, like the need will, I would like to take to cure this disease I have not yet become a serious bulimia. Recall When did you start this overeating phenomenon it? That is, from my college entrance examination after the weight loss began. Life for the first time overeating is the first time I lose weight 28 days, I was suddenly mad to eat something, but the head and said to myself of NO. Taking effective fruta planta pills to reduce blood homocysteine levels is helpful.But my hand or involuntary picked up two loaves of bread to pay for my awareness can not control my body. In this way, I did eat all the way back to eat the stomach to explode, and stopped. The next day I thought to put up so long for their hard work in vain, began to give up on themselves every day to eat a body suddenly blowing up. And when I was working in the bakery to purchase large amounts of bread at night secretly drops away, to go to work tired, I often next evening eleven home, walked to eat bread, the deepest impression is the time to eat 7 also includes a large kind of heavy. effective fruta planta can effectively prevent diabetes and improve the health condition of users.

Always cold or hot? Heart racing a mile a minute? Whether underactive or overactive, thyroid disease symptoms can make your body feel out of whack. Knowing the symptoms can help your doctor diagnose the problem and get you feeling better fast. Do you know what to look for?

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It's estimated that 59 million Americans have a thyroid problem, but the majority don't even know it yet. The thyroid, a butterfly-shaped gland located in the neck, is the master gland of metabolism. When your thyroid doesn't function, it can affect every aspect of your health, and in particular, weight, depression and energy levels.

Since undiagnosed thyroid problems can dramatically increase your risk of obesity, heart disease, depression, anxiety, hair loss, sexual dysfunction, infertility and a host of other symptoms and health problems, it's important that you don't go undiagnosed.

You don't need to have all of these symptoms in order to have a thyroid problem, but here are some of the most common signs that you may have a thyroid condition:

1. Muscle and Joint Pains, Carpal Tunnel/Tendonitis Problems.

Aches and pains in your muscles and joints, weakness in the arms and a tendency to develop carpal tunnel in the arms/hands and tarsal tunnel in the legs, can all be symptoms of undiagnosed thyroid problems.

2. Neck Discomfort/Enlargement.

A feeling of swelling in the neck, discomfort with turtlenecks or neckties, a hoarse voice or a visibly enlarged thyroid can all be symptoms of thyroid disease.

3. Hair/Skin Changes.

Hair and skin are particularly vulnerable to thyroid conditions, and in particular, hair loss is frequently associated with thyroid problems. With hypothyroidism, hair frequently becomes brittle, coarse and dry, while breaking off and falling out easily. Skin can become coarse, thick, dry, and scaly. In hypothyroidism, there is often an unusual loss of hair in the outer edge of the eyebrow. With hyperthyroidism, severe hair loss can also occur, and skin can become fragile and thin.

The couple before preparing to want the child, should be the same as to go to the hospital to check, to confirm there is no disease, guarantee the pregnancy success. Because of illness and the nature of symptoms to determine whether pregnancy.The following diseases in pregnancy should be treated before: anemia. Severe anemia, not only makes the pain was pregnant, but also affect fetal development, unfavorable to postpartum recovery. If anemia disease, to fully take in food are iron and protein and iron supplementation, anemia was treated, can be pregnant.Tuberculosis. Tuberculosis directly transmitted to the fetus, so in a prior pregnancy must be cured. Heart disease. Abnormal heart function can cause blood circulation disorder, caused by abnormal placental blood vessels, leading to miscarriage, premature birth, maternal body and life are threatened, so before pregnancy must heal and listen to the doctor's advice.Renal disease in patients with kidney disease. Once the pregnancy, as the pregnancy continues to exacerbations, cause miscarriage, premature, there must be a termination of pregnancy. According to kidney disease and symptoms, consult if the doctor can pregnancy.Hypertension. Hypertension patients predisposed to hypertension syndrome of pregnancy, and can become severe. On their own blood pressure values are not very clear, if there is severe headaches, shoulderShoulder pain, insomnia, dizziness and swelling and other symptoms will go to the hospital to check.Liver disease. After pregnancy, liver burden, such as liver disease, can cause liver disease progression, such as serious illness to terminate the pregnancy, if the condition is not serious, under the guidance of a doctor, can continue to pregnancy.Pregnant women suffering from diabetes. Diabetes mellitus, can cause miscarriage, premature birth, sometimes in intrauterine fetal death. In addition students macrosomia, deformity rate will increase.According to the disease degree, consult a doctor can pregnancy. Cystitis, pyelonephritis. Cystitis can develop pyelonephritis, symptoms are frequent urination, urinary endless and dysuria. Suffering from cystitis women, must be cured only after pregnancy.Vaginitis vaginitis. There are many, many are caused by Candida infection. If in spite of childbirth, will infect the fetus, so that newborns suffering from thrush disease. More exciting content to humanhealth the new product you health I Services PICC health insurance knowledge in product introduction insurance healthy male female health real-time news financial services company of PICC Health Insurance