Chugai Pharmaceutical Co. Ltd. (4519) jumped after its parent company Roche Holding AG
RHHDY
said there was no clear evidence its flu drug Tamiflu had contributed to the deaths of two Japanese teenagers, as weekend news reports had suggested.

Mitsubishi Motors Corp. (7211) plunged 10.7% to a one-month low of 234 yen, extending Monday's decline. The stock met a flurry of sales after the automaker said a unit of Goldman Sachs sold to undisclosed parties the 12.4% stake in Mitsubishi Motors it bought from DaimlerChrysler AG
DCX

Elsewhere, China's factories kept up a hot pace in October as booming exports and strong investment boosted industrial output by 16.1% from a year earlier, the National Bureau of Statistics said.

Also in China, Standard & Poor's on Tuesday upgraded the rating of top offshore oil producer CNOOC Ltd.
CEO, -0.53%
by one notch to A-minus.

In Seoul, Posco Co.
PKX, -0.82%
the world's fifth-biggest steel maker, is set to raise $690.6 million in a Japanese share offering, the company said, making it the first South Korean firm to list in Tokyo.

The money raised could allow Posco to finance its foreign expansion and potentially allow it to catch up to regional rivals, such as Nippon Steel Corp. (5401) and JFE Holdings (5411), in terms of valuation.

Also in IPO news, Australian food group Burns, Philp & Co. Ltd. plans to raise up to A$2.1 billion ($1.5 billion) from a share offering in its Goodman Fielder business, after rejecting a bid from a private equity consortium.

The IPO will be the world's ninth biggest this year and takes the value of Australian IPOs announced this month to A$5.5 billion, Reuters reported.

U.S. stocks ended mixed Monday on some caution ahead of key inflation and retail-sales data due later in the week. See full story

The Dow Jones Industrial Average
DJIA, +0.72%
ended at a fresh three-and-a-half-month high, up 11.13 points at 10,697.17. The Nasdaq Composite Index
$COMPX
fell 1.52 points to 2,200.95, while the S&P 500 Index
SPX, +0.59%
was off 0.96 points at 1,233.76.

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