2013 Investor Warrants were exercised at $3.144 per share for cash proceeds of $204,659.

[2]

Warrants issued to Valent (note 4) were exercised at $1.54 (CDN $2.00) per share for cash proceeds of $192,075.

[3]

2015 Investor Warrants were exercised at $3.00 per share for cash proceeds of $146,250.

[4]

680 of the 2015 Agent Warrants were exercised at $3.00 per share for cash proceeds of $2,040 and 1,000 of the 2015 Agent Warrants were exercised on a cashless basis for 594 shares of common stock.

[5]

Warrants were issued on February 27, 2017 and are exercisable at $5.93 until they expire on February 27, 2020. They vest pro rata over six months from February 27, 2017 and are exercisable commencing 180 days from the date of issuance.