Pharmacist Only Medicine

MoviPrep

Pharmacist Only Medicine

MoviPrep

$36.90

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MoviPrep

A successful colonoscopy starts with a complete colonoscopy prepColonoscopy is the best available test for detecting and preventing colon cancer, but a successful colonoscopy requires a complete colonoscopy prep. Chances are you've heard that preparing for a colonoscopy is no picnic. It's true. The colonoscopy prep process may not be the most glamorous activity, but it is crucial to this potentially lifesaving procedure. That's because an effective colonoscopy prep allows your doctor to examine the entire lining of your colon for abnormal growths, which may grow into cancer if they are not detected and removed.

MoviPrep is a low-volume colonoscopy prep that is proven to provide a clear view of the entire colon, allowing your doctor to detect abnormal growths.1 That's one reason why MoviPrep has been prescribed over 8 million times since 2006.2

Your helpful guide for the colonoscopy prep process

Rest assured, getting a colonoscopy is time well spent toward living a healthier lifestyle. To help make the process more tolerable, we created this Web site to help guide you through the weeks and days leading up to your colonoscopy. Within the site, you will find helpful tools, such as the My MoviMent Prep Kit and a sample calendar for the time leading up to your colonoscopy . You can also read about others' experiences and learn more about the colonoscopy prep, colonoscopy, and colon cancer.

MOVIPREP is indicated for cleansing of the colon as a preparation for colonoscopy in adults 18 years of age or older. MoviPrep has proven 89% excellent or good cleansing when used as a split dose—efficacy that has been proven in clinical trials.2

MOVIPREP is a well-tolerated, low-volume polyethylene glycol (PEG) bowel prep. MOVIPREP has been proven more tolerable than 4-L preparations, with less nausea, vomiting, and abdominal pain.2Indication for MOVIPREP

MOVIPREP® (PEG-3350, sodium sulfate, sodium chloride, potassium chloride, sodium ascorbate and ascorbic acid for oral solution) is an osmotic laxative indicated for cleansing of the colon as a preparation for colonoscopy in adults 18 years of age or older.

Important Safety Information about MOVIPREP

Do not take MOVIPREP® (PEG-3350, sodium sulfate, sodium chloride, potassium chloride, sodium ascorbate and ascorbic acid for oral solution) if you have a gastrointestinal (GI) obstruction (a blockage in your bowel), bowel perforation (an opening in the wall of your stomach or intestine), gastric retention (problems with food and fluid emptying from your stomach), ileus (bowel muscle unable to move stomach contents), toxic colitis (damage to the thickness of the intestinal wall) or toxic megacolon (an extremely dilated or distended colon with fever and/or abdominal pain at times), or if you have a known allergy to MOVIPREP or any of its components.

It is important to drink sufficient liquids before, during, and after the use of MOVIPREP. Liquid and blood salt changes can lead to serious side effects including abnormal heartbeats, seizures, and kidney problems. Talk to your doctor before taking MOVIPREP if you take any medications that increase the risk of blood salt abnormalities or if you have known or suspected low blood salt (sodium) level (hyponatremia).

If you have kidney problems or if you take medication that affects kidney function, talk to your doctor before taking MOVIPREP.

If you have suspected bowel blockage or a suspected opening in the wall of your stomach or intestine, talk to your doctor before taking MOVIPREP.

Talk to your doctor before taking MOVIPREP if you have problems swallowing, if you have gastric reflux, or if you are predisposed to aspiration.

If you have a condition that destroys red blood cells called glucose-6-phosphate dehydrogenase (G6PD) deficiency, talk to your doctor before taking MOVIPREP.

Please be advised that MOVIPREP contains 131 mg of phenylalanine per treatment.

If you are pregnant or planning to become pregnant, talk to your doctor before taking MOVIPREP.

-Pour entire contents of the 6 oz oral solution bottle into the 16 oz mixing container and then fill to the fill line with cool water and mix-Drink the entire solution in the container within 20 minutes-Refill the container with 16 oz of water to the fill line and drink it over the next 2 hours-Refill the container with another 16 oz of water and drink it before going to bed

Dose 2: Next morning at least 3 and 1/2 hours prior to colonoscopy:

-Dissolve the powder by adding water to the fill line on the jug.-Shake the jug until all powder is dissolved.-Using the 16 oz container provided, drink all the solution in the jug at a rate of one 16 oz container every 20 minutes.-Refill the container to the fill line with 16 oz of water and finish drinking it before bed.-Complete drinking the solution at least 2 hours before the colonoscopy.-Consume only clear liquids until 2 hours prior to colonoscopy. Then nothing should be consumed until after the colonoscopy.

-Pour entire contents of the 6 oz oral solution bottle into the 16 oz mixing container and then fill to the fill line with cool water and mix.-Drink the entire solution in the container within 20 minutes.-Refill the container with 16 oz of water to the fill line and drink it over the next 2 hours.

Dose 2 (Approximately 2 hours after Dose 1):

-Dissolve the powder by adding water to the fill line on the jug.-Shake the jug until all powder is dissolved.-Using the 16 oz container provided, drink all the solution in the jug at a rate of one 16 oz container every 20 minutes.-Complete drinking the solution at least 2 hours before the colonoscopy.-Consume only clear liquids until 2 hours prior to colonoscopy. Then nothing should be consumed until after the colonoscopy.

Comments: Dose 2 solution can be used with or without flavor packets. When dissolved in water the Dose 2 solution should be clear and colorless. The Dose 2 solution may be refrigerated but should be used within 48 hours.

Usual Adult Dose for Gastrointestinal Decontamination

1 to 2 liters per hour orally or via nasogastric tube until the effluent is clear. Polyethylene glycol electrolyte solution is sometimes administered in combination with activated charcoal, however, charcoal adsorption may occur.

Usual Adult Dose for Constipation - Chronic

240 to 480 mL (8 to 16 fluid ounces) orally once a day.

Renal Dose Adjustments

No adjustment recommended; use with caution

Liver Dose Adjustments

No adjustment recommended

Precautions

Consult WARNINGS section for dosing related precautions.

Dialysis

No adjustment recommended

Other Comments

Administration advice: Each bottle needs to be diluted in water before ingestion; direct ingestion of the undiluted solution may increase the risk of nausea, vomiting, and dehydration. Oral medications may not be absorbed properly if they are taken within one hour of starting each dose. Solid food should not be given within 2 hours of administration of the solution. The addition of sweeteners or other additives to the solution may alter the osmolality or cause the formation of explosive gas.

General: Administration of the PEG-ELS is best accomplished when given to a patient capable of sitting on a commode. When given to an unconscious patient, or one that is unable to sit on a commode, a rectal tube may be placed to drain the effluent.

Patient advice: Consume only clear liquids (no solid food or milk). Do not eat or drink anything red or purple. Do not to take other laxatives. Avoid alcohol on the day before colonoscopy until after completion of the colonoscopy. Stay adequately hydrated before, during, and after treatment.

This Medication Guide has been approved by the U.S. Food and Drug Administration.

Warnings

How should I store MoviPrep?

• Store MoviPrep that has not been mixed with water at room temperature, between 68°F to 77°F (20°C to 25°C).

• Store MoviPrep that has been mixed with water in an upright position in the refrigerator.

• MoviPrep should be taken within 24 hours after it has been mixed with water.

Keep MoviPrep and all medicines out of the reach of children.

General information about the safe and effective use of MoviPrep.

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use MoviPrep for a condition for which it was not prescribed. Do not give MoviPrep to other people, even if they are going to have the same procedure you are. It may harm them.

This Medication Guide summarizes the most important information about MoviPrep. If you would like more information, talk with your healthcare provider. You can ask your pharmacist or healthcare provider for information that is written for health care professionals.