Released in 2003, Red, White & Liberal tackles issues such as civil rights, the war on terror, and the perceived liberal media bias. Moreover, Colmes asserts that Bill Clinton was America's greatest president, that O. J. Simpson was innocent, and that Jesus was a liberal. Interspersed throughout are actual emails from Hannity & Colmes viewers, reprinted verbatim.

The book was prominently advertised on the website of Alan Colmes' conservative counterpart, Sean Hannity.