Clomiphene

Trade Names :

Clomiphene is used to enhance female fertility. Use of clomiphene increases levels of follicle stimulating hormone (FSH), which in turn causes the ovaries to bring more eggs to maturity. Clomiphene is particularly helpful for women with
polycystic ovary syndrome
.

The supplement N-acetylcysteine (NAC) has shown promise for enhancing the effectiveness of clomiphene. A double-blind study enrolled 150 women with PCOS for whom clomiphene had not been effective.
1
Half were given NAC at a dose of 1.2 g per day, while the other half received placebo. All participants continued to receive clomiphene. The results showed that use of NAC significantly improved both ovulation rate and pregnancy rate.

Traditional Chinese Herbal Medicine employs complex combinations of herbs. Several studies conducted in China reported that use of such combinations can enhance the effectiveness of clomiphene.
2-6
Unfortunately, none of these studies achieved the minimum standards necessary for scientific validity.

Revision Information

This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.