Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.

Positive Controls

HEK 293T, HeLa nuclear extract

Form Supplied

Liquid

Purification

Purified by affinity chromatography

Specifications: O-GlcNAc transferase antibody

Full Name

O-linked N-acetylglucosamine (GlcNAc) transferase

Background

O-linked N-acetylglucosamine transferase (OGT) catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects.