I’ve been searching for companies that developed native 64-bit TWAIN drivers for their scanners, but I seem to only find drivers that work with WoW (I’m assuming those drivers are 32-bit). Is development of native 64-bit TWAIN drivers uncommon? Other than searching for drivers of various scanners, is there a centralized source where I could find this? This is anecdotal, but tech support people for scanner manufactures don’t seem to understand the difference between an OS’s bit version and the driver’s bit version. So I’m skeptical of the information they’re giving me.

We have developed native 64 bit TWAIN drivers for scanner manufacturers. Due to the nature of the OEM business we are not allowed to publish the names here in a forum. But I have approval to guide you by personal message.

I am using twain_32.dll for scanner application and it is using as activex for my web application. it is working fine in windows7. when I have upgrade to windows10 OS. Scanner option is not working. twain_32.dll is crashing. Please let me know how to solve this issue for windows 10?

The 64 bit computers can run both 32bit programs and 64 bit programs. 32 bit computers cannot run 64 bit programs, because the bit sizes are fundamentally different. Latest Laptops with pre-installed Windows are usually x64 i.e. 64 Bit, old Desktops and Laptops could be having Windows x86 which means 32 bit.