She tweeted an image of the offensive Facebook post, calling on Premier Annastacia Palaszczuk and Deputy Premier Jackie Trad to join her in calling out the "disgusting behaviour".

Neither Labor leader responded.

The offensive Facebook post followed Ms O'Dwyer's shock resignation within the Federal LNP Government, citing family issues and suffering a miscarriage in Parliament House.

The post was made by an account called Union News Australia.

"I don't care your politics, this treatment of a female politician is totally unacceptable. I am calling on @AnnastaciaMP and @jackietrad to show some leadership and call out this disgusting behaviour today. #qldpol #auspol," Ms Frecklington tweeted, along with a screenshot of the Facebook Post captioned 'bye, bye, b*tch'.