Selective IgA deficiency

Common Name(s)

Selective IgA deficiency

Selective IgA deficiency refers to the complete or severe deficiency of IgA. This deficiency makes one more prone to infections, allergies, diarrhea, and autoimmune diseases. It is the most common type of primary immunodeficiency and is caused by a lack of mature B-lymphocytes. Why the B-lymphocytes fail to mature and produce IgA is not clear. Familial occurrence has been reported in the medical literature, some cases were suggestive of autosomal dominant inheritance, others of autosomal recessive inheritance.

How do you compare to others with this condition?

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

Advocacy and Support Organizations

Condition Specific Organizations

Following organizations serve the condition "Selective IgA deficiency" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

General Support Organizations

Recommended Apps

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

Finding the right clinical trial for Selective IgA deficiency can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Selective IgA deficiency" returned 56 free, full-text research articles on human participants.
First 3 results:

The pathogenesis of some primary humoral immunodeficiencies, such as transient hypogammaglobulinemia of infancy (THI) and immunoglobulin (Ig) A deficiency, remains unknown and can render diagnosis problematic.

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Selective IgA deficiency" returned 3 free, full-text review articles on human participants.
First 3 results:

Selective immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency in Caucasians. It has previously been suggested to be associated with a variety of concomitant autoimmune diseases. In this review, we present data on the prevalence of IgAD in patients with Graves ...

Immunoglobulin A (IgA) deficiency is the most common primary immunodeficiency defined as decreased serum level of IgA in the presence of normal levels of other immunoglobulin isotypes. Most individuals with IgA deficiency are asymptomatic and identified coincidentally. However, some ...

According to ClinicalTrials.gov there are currently 0 additional "open" studies for "Selective IgA deficiency" (open studies are recruiting volunteers) and 1 "Selective IgA deficiency" studies with "all" status. Visit ClinicalTrials.gov now to view them. Or alternatively, consider TrialsFinder for assistance:

Relief is when you and the right researcher find each other
Finding the right clinical trial for Selective IgA deficiency can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.