Platinum (Pt) drugs such as oxaliplatin and cisplatin are important in the treatment of cancer; however their clinical use is limited by the development of resistance. Pt drug cytotoxicity is mainly attributed to the ...

Photodynamic therapy (PDT) is a treatment for cancer which combines the administration of a drug, known as a photosensitizer, with light. When the photosensitizer is irradiated with the light, it produces singlet oxygen ...

Changes in HLA class I antigen and NK cell-activating ligand expression have been identified in malignant lesions. These changes are believed to play a major role in the clinical course of the disease since both HLA class ...

The 1986 nuclear reactor meltdown in Chernobyl, Ukraine remains one of the largest and most notable human-made environmental disasters. Radiation contamination from the disaster was widespread, with the greatest concentrations ...

The purpose of this study is to determine the heritability of occlusal traits in primary dentitions of Brazilian Twins using a twin study design. 16 pairs of monozygotic (MZ) identical twins casts and 19 pairs of dizygotic ...

Background . The success of surgical Endodontics procedures is often dependent on the properties of the retrograde filling material. Providing a reliable apical seal is the main objective of a root-end filling material ...

Current cancer therapy relies on inducing apoptosis in tumor cells. While apoptosis provides an effective strategy to eradicate cancer, obstacles such as high levels of host toxicity and resistance, remain. Intriguingly, ...

The primary goal of this study was to identify salivary biomarkers associate with periodontal disease activity. Ninety eight samples of whole saliva were collected from untreated subjects initially presenting to the dental ...

Growth, development, and function of the prostate gland are regulated through the androgen receptor (AR), and prostate cancer is associated with aberrant regulation of the AR. Three isoforms of a recently discovered calcium ...