Immunology, Inflammation and Diseases of the Eye

This selection of articles from the Encyclopedia of the Eye provides a comprehensive overview of immunological features, diseases and inflammation of the eye and its support structures and organs. Rather than taking an immunological focus that is strictly suitable for clinicians, the volume offers a considerable basic science background and addresses a broad range of topics - the immune system of the eye, its various disorders, mechanisms of inflammation of the eye and visual system, treatment, wound healing mechanisms, stem cells, and more.

Contents

I. Regulation of the Immune Response of the Eye and Its Dysregulation in Inflammation and InfectionAdaptive Immune System and the Eye: Mucosal ImmunityAdaptive immune system and the eye: T-cell mediated immunityInnate immune system and the eyeDefense mechanisms of tears and ocular surfaceRole of complement in the ocular immune responseImmunoregulatory processes that sustain immune privilege in the eyeImmunosupressive and anti-inflammatory molecules that maintain immune previlege of the eyeAntigen-presenting cells in the eye and ocular surfaceRegenfus and Cursiefen- Angiogenesis in the eyeDry eye: An immune-based inflammationPenetrating keratoplastyCorneal epithelium- response to infectionImmunopathogenesis of HSV KeratitisImmunopathogenesis of Onchocerciasis (River Blindness)Immunopathogenesis of pseudomonas keratitisImmunobiology of acanthomeba karatitisPathogenesis of fungal keratitisMolecular and cellular mechanisms in allergic conjunctivitisConjunctiva Immune surveillanceInflammation of the ConjunctivaImmunopathogenesis of experimental uveitic diseasesPathogenesis of Uveitis in humansImmunobiology of uveal melanomaImmunobiology of age-related macular degenerationPathogenesis and Immunology of Bacterial endophthalmitis

II. Angiogenesis in the Eye and Its Dysfunction in the Retina, Cornea and VitreousOrbiatl vascular anatomy Developmental anatomy of retinal and choroidal vasculatureDevelopment of the retinal vasculaturePhysiological Anatomy of the retinal vasculaturePhysiological anatomy of the choroidal vasculatureProperties and functions of the vessels of the ciliary bodyAnatomy and regulation of the optic nerve blood flowAngiogenesis in response to hypoxiaAngiogenesis and inflammationAngiogenesis in wound healingHemangiogenesis versus lymphangiogenesisInnate immunity and angiogenesisMechanisms of AngiostasisStability and functional integrity of new blood vesselsVessel regressionBlood-retinal barrierBreakdown of the blood-retinal barrierRetinal pigment epithelium barrierBreakdown of the retinal pigement epithelium blood-retinal barrierRetinal pigment epithelial-choroid interactionsMacular edemaCentral vein occlusionPathological retinal angiogenesisProliferative vitreoretinopathyChoroidal neovascularizationThe vascular stem cellConcept of Angiogenic PrivilegeCorneal angiogenesisAvascularity of the corneaAnti-angiogenic properties of vitreous