Microzide (Hydrochlorothiazide (Hctz)) is a thiazide diuretic (water pill). It works in the kidneys to make you urinate more, which removes extra water and certain electrolytes. This lowers blood pressure and swelling.

Aldactazide (Spironolactone / Hydrochlorothiazide) is a combination medicine that lowers your blood pressure with two diuretics (water pills), hydrochlorothiazide and spironolactone. They act on different parts of your kidney to get rid of extra fluids.