Browse our anti-FOXO1 (FOXO1) Antibodies

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anti-Forkhead Box O1 Antibodies (FOXO1)

On www.antibodies-online.com are 490 Forkhead Box O1 (FOXO1) Antibodies from 39 different suppliers available. Additionally we are shipping FOXO1 Kits (65) and FOXO1 Proteins (10) and many more products for this protein. A total of 586 FOXO1 products are currently listed.

miR-486-5p can inhibit inflammatory response, ECM degradation and apoptosis in NP cells by directly targeting FOXO1, which may contribute to the biological therapy of intervertebral disc degeneration.

Low FOXO1 expression is associated with cancer.

The reciprocal expression of PGR and FOXO1 was conserved in endometrial samples during the proliferative and secretory phase. Expression of FOXO1 and the loss of PGR during the window of receptivity are interrelated and critical for embryo implantation.

The presence of FOXO1 (and SESN3 and TSC2) were identified in Lewy bodies from brainstem.

Zebrafish Forkhead Box O1 (FOXO1) interaction partners

The findings reveal a novel mechanism by which Ca2+ overload disrupts myofibril integrity by activating a Calcineurin-FoxO-MuRF1-proteosome signaling pathway.

These results indicate that miR-182 functions as a FoxO1 inhibitor to antagonize osteoblast proliferation and differentiation, with a subsequent negative effect on osteogenesis.

gas6 protects endothelial cells from apoptosis by a mechanism that involves PI3K-Akt-dependent inactivation of FOXO1a.

Mouse (Murine) Forkhead Box O1 (FOXO1) interaction partners

These results indicate that liver FoxO1 promotes serpinB1 expression in hepatic insulin resistance and that non-cell-autonomous factors contribute to FoxO1-dependent effects on serpinB1 expression in the liver.

FOXO1 is continuously required for all the phenotypic characteristics of memory-effector T cells such that with acute inactivation of the gene encoding FOXO1, T cells revert to a short-lived effector phenotype, exhibit reduced viability, and manifest characteristics of anergy.

Results demonstrate that the timing of FOXO1 activation affects its role in pituitary gland organogenesis and somatotrope differentiation.

High Foxo1 expression is associated with cardiac dysfunction.

Demonstrate that the transcription factor Forkhead Box O1 (FOXO1) is a critical regulator of endometrial receptivity in vivo. Uterine ablation of Foxo1 using the progesterone receptor Cre (PgrCre) model resulted in infertility due to altered epithelial cell polarity and apoptosis, preventing the embryo from penetrating the luminal epithelium.

The results together illustrated that as a major regulator in redox homeostasis and osteoblast physiology, FoxO1 provides a favorable intracellular environment for osteoblast functions by defensing against the adverse effects of oxidative stress.

CD226 regulation of NK cell cytotoxicity is facilitated through inactivation of FOXO1. Gene-expression analysis of NK cells isolated from syngeneic tumors grown in wild-type or CD226-deficient mice revealed dysregulated expression of FOXO1-regulated genes in the absence of CD226.

The results indicate that chondrocytes play a prominent role in diabetes-impaired fracture healing and that high levels of glucose, AGEs, and tumor necrosis factor-alpha, which are elevated by diabetes, alter RANKL expression in chondrocytes via FOXO1.

data reveal the pervasive role of forkhead box O1(FoxO1) in mediating the effects of insulin on not only glucose metabolism but also other hormonal signaling pathways and even some aspects of lipid metabolism

FOXO1 deletion in epithelium led to impaired healing that included decreased formation of new connective tissue.

Pig (Porcine) Forkhead Box O1 (FOXO1) interaction partners

Studied the effects of microRNA-27a on myogenin expression and the Akt/FoxO1 signal pathway during porcine myoblast differentiation. Overexpression of miR-27a suppressed myogenin expression during porcine myoblast differentiation, whereas inhibition of miR-27a promoted the mRNA and protein expression levels of myogenin; overexpression of miR-27a decreased the level of P-Akt/Akt and increased the protein level of FoxO1.

he knockdown of FoxO1 repressed lipogenesis by downregulating PDGFRalpha, and miR-34a inhibited adipogenesis through targeting PDGFRalpha.

These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing the activation of TLR4 and/or NOD2 signaling pathways.

Data show that IL-4 induces upregulation of the junction protein claudin-5 in endothelial cells (ECs) through activation of Jak/STAT6 and phosphorylation and translocation of FoxO1 from the nucleus to the cytoplasm.

FoxO1 delays and negatively regulates the porcine myoblast differentiation. It may also play a critical role in muscle fiber-type specification through the inhibition of myogenic regulation factors.

concluded that PI 3-kinase and Akt are activated after renal ischemia/reperfusion and that Akt phosphorylation leads to phosphorylation of FKHR and FKHRL1, which may affect epithelial cell fate in acute renal failure.

FoxO1a can regulate p27kip nuclear localization

FoxO1 expression level has a negative correlation with the development of muscle fiber

results suggested that porcine FoxO1 gene took part in the regulation of adipose and was a negative transcription regulation factor in preadipocyte differentiation

Cow (Bovine) Forkhead Box O1 (FOXO1) interaction partners

This is the first study demonstrating a role for AMPK-SIRT1-FOXO1 signalling pathway in regulating apoptosis in bovine intramuscular adipocytes.

The results demonstrate pathways through which two different mediators, TNF-alpha and an advanced glycation endproduct, can induce pericyte apoptosis through activation of the transcription factor FOXO1.

Rhesus Monkey Forkhead Box O1 (FOXO1) interaction partners

FOXO1, 3, and 4 as well as their upstream regulator, AKT/p-AKT, was examined in rhesus macaque ovaries of three developmental stages: fetal, prepubertal, and adult

Xenopus laevis Forkhead Box O1 (FOXO1) interaction partners

FoxO1 translocation to the nucleus, and the increase in FoxO1 DNA binding activity in X. laevis liver strongly correlate with the up-regulation of manganese-dependent superoxide dismutase and catalase mRNA and protein levels in this organ.

FOXO1 Antigen Profile

Antigen Summary

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined\; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.