Complaint of headache is a frequent application to the emergency department. Most of the patients have benign primary headache so a fast and effective treatment is sufficient. A 24-year-old patient was admitted to the emergency department with symptoms of headache, slowing down in speech, numbness and weakness on the left side. After the examinations, the patient was diagnosed with hemiplegic migraine attack. During follow-up, the patient's muscular weakness and symptoms totally improved and migraine prophylaxis was started. Hemiplegic migraine, a rare subtype of migraine, characterized by recurrent focal weakness and headache episodes, was reviewed on this case.