Digestion of beta-LPH with other enzymes such as renin, cathepsin D, trypsin, and chymotrypsin produced much less opiatelike activity. beta-Endorphin and methionine-enkephalin were not cleaved by tonin.

Comparisons between the controls and the three study groups revealed increased pyruvate and increased lactate (L) production in FMS and HO; decreased adenosine triphosphate (ATP) and lactase dehydrogenase (LDH) isoenzymes in FMS only; and no glycolytic impairment in OACP.