A single dose of PEAK ATP® supplementation was shown to reduce systolic blood pressure after aerobic exercise and induced a faster recovery of heart rate variability.

A double-blind, randomized study of 11 hypertensive women were given either placebo or 400-mg of ATP supplementation randomly, and then completed 30 minutes of moderate to vigorous aerobic exercise. Post exercise blood pressure and heart rate variability were evaluated. The results of the study suggest that ATP supplementation can be used as a nutritional strategy to induce faster recovery of heart rate variability after exercise by increasing parasympathetic modulation and may be used to potentiate the reduction of systolic blood pressure after exercise in hypertensive women.