OBJECTIVE: 1) To compare cognitive and psychiatric outcomes 3 years after GPi DBS versus STN
DBS, and 2) to report on occurrence of suicidal ideation, psychiatric diagnoses, social functioning, and marital satisfaction
3 years after DBS.

RESULTS:
Eighty-seven patients (68%) completed at least one neuropsychological test after 3 years. No significant between-group differences
were found on the MDRS (p = 0.61), neuropsychological tests (p-values between 0.17 and 0.87), and psychiatric questionnaires
(p-values between 0.23 and 0.88) 3 years after DBS. The Mini International Neuropsychiatric Interview did not indicate a substantial
number of psychiatric diagnoses after 3 years. Social functioning and marital satisfaction were comparable in both groups.

CONCLUSIONS:
Three years after GPi DBS and STN DBS no pronounced between-group differences on measures of cognitive and psychiatric functioning
could be demonstrated. Overall, cognitive and psychiatric outcome 3 years after DBS do not provide a clear direction for clinicians
when considering which of these two surgical targets to choose.

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