The cartel is global with business in the US, Mexico, Europe, Asia and Australia

Nemesio Ruben Oseguera Cervantes, 52, is known as “El Mencho.” He is a fugitive and was designated as a “Kingpin” under the Foreign Narcotics Kingpin Designation Act by the Department of the Treasury in April 2015.

The reward for Oseguera Cervantes’s arrest is the highest the government offers for narcotics fugitives.

His son, known as “Menchito,” is in custody in Mexico and awaiting extradition to the U.S.

The new plans include putting greater emphasis on attacking cartels' financial infrastructure and calling for a new enforcement group based in Chicago that will concentrate on international investigations of cartels.

A 2018 report by the University of San Diego's Justice in Mexico said Guzman's takedown "dramatically reshaped the landscape of Mexican organized crime," including by clearing the way for the rise of CJNG. It added the cartel's 52-year-old leader "has a reputation as a ruthless killer." He migrated to the U.S. in the 1980s and was deported back to Mexico after a trafficking conviction.