Anderson Cooper may be known for occasionally cracking up on air, but one of the guests on his daytime talk show this week definitely did not leave him laughing.

In fact, she simply left altogether, at the request of the host himself.

Cooper was chatting on Tuesday with Sarah Burge, a British woman who calls herself the "human Barbie" because she has reportedly spent hundreds of thousands of dollars on plastic surgery, when he began grilling her on how she gave her 8-year-old daughter vouchers for breast implants (to be redeemed upon turning 18) and encouraging her 15-year-old daughter to get Botox.

The breaking point for Cooper occurred when Burge was explaining that her 15-year-old, a dancer, didn't want to be seen perspiring while performing and so Burge suggested she get a shot of Botox..

"I would prefer to actually oversee my daughter's Botox than actually have her go underground, find a voodoo witch doctor or getting it off the Internet and administering it herself," Burge said.

With that, Cooper paused and said, "Um, I honestly have nothing more to talk to you about. I got to stop, sorry. I try to be really polite to all my guests, but I think you're dreadful and I honestly don't want to talk to you anymore."

"That's fine, that's fine," Burge replied as she walked off the set.

Backstage after the show, Cooper said on camera, "I got the feeling this was about publicity for her. I regret having her on in the first place and I regret how things ended."