history of stroke, transient ischemic attacks (TIAs or mini-strokes), or intracranial bleeding

kidney or liver disease

overweight

poor circulation

postmenopausal or surgical removal of uterus and ovaries

Raynaud's disease

seizure disorder

an unusual or allergic reaction to almotriptan, other medicines, foods, dyes, or preservatives

pregnant or trying to get pregnant

breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. This medicine is taken at the first symptoms of a migraine. It is not for everyday use. If your migraine headache returns after one dose, you can take another dose as directed. You must leave at least 2 hours between doses, and do not take more than 25 mg total in any 24 hour period. If there is no improvement at all after the first dose, do not take a second dose without talking to your doctor or health care professional. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply; this medicine is not for regular use.

What may interact with this medicine?

Do not take this medicine with any of the following medicines:

amphetamine or cocaine

dihydroergotamine, ergotamine, ergoloid mesylates, methysergide, or ergot-type medication - do not take within 24 hours of taking almotriptan

feverfew

MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate - do not take almotriptan within 2 weeks of stopping MAOI therapy

other migraine medicines like eletriptan, naratriptan, rizatriptan, zolmitriptan - do not take within 24 hours of taking almotriptan

tryptophan

This medicine may also interact with the following medications:

erythromycin

lithium

medicines for fungal infections like ketoconazole and itraconazole

medicines for mental depression, anxiety or mood problems

medicines for weight loss such as dexfenfluramine, dextroamphetamine, fenfluramine, or sibutramine

ritonavir

St. John's wort

What should I watch for while using this medicine?

Only take this medicine for a migraine headache. Take it if you get warning symptoms or at the start of a migraine attack. It is not for regular use to prevent migraine attacks.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. To reduce dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can increase drowsiness, dizziness and flushing. Avoid alcoholic drinks.

Smoking cigarettes may increase the risk of heart-related side effects from using this medicine.