Secondary Screening Kits

After the initial screening to find the best combination of resolving agent and solvent that offers maximum yield and purity of the enantiomer, scientists then need to further qualify their findings to see if a specific derivative of the resolving agent can offer better results; or if it reduces the number rystallization steps get the desired purity of the target enantiomer. These steps also have to be fine-tuned to minimize the amount of raw material needed, amount of chemical waste, etc. To help fine-tune the target resolving agent, ChiroSolve offers:

Acid kits with derivatives of a specific acid resolving agent

Strongly acid kits for weakly base racemates

We recommend that the Process Chemists do this additional screening before establishing their manufacturing route; since it may result into tremendous time and money saving for the company. In one such example, we were able to reduce the number of recrystallization steps from 4 to 3 by doing such screening.