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"Integrated Structural Biology is at a critical stage; failure is not an option..."

Prof. Dave Stuart

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The Protein Crystallisation Construct Designer (ProteinCCD) is a tool to help deciding how to choose promising constructs for protein expression and crystallisation. A specific feature of CCD is that since it starts from the DNA sequence, it keeps track of the protein-DNA relationship. Thus, although all the analysis and construct choice is being done in the protein level, CCD can be used to suggest primers for PCR amplification of the chosen constructs, since it also knows the DNA sequence.

The PDB_REDO server is a tool for macromolecular X-ray crystallographers who wish to optimize the refinement of their structure. It takes as input the coordinates of a macromolecular structure you are working on (PDB file), together with the associated X-ray diffraction data (MTZ file), and returns a refined and partially rebuilt model and a validation report.