Granger Sutton, PhD

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Bio

Granger Sutton, PhD is a professor at the J. Craig Venter Institute (JCVI) where his primary role is to coordinate the prokaryotic informatics group and oversee all aspects of shotgun fragment assembly. Prior to joining JCVI, Dr. Sutton was a director in the Informatics Research department at Celera Genomics from 1998 to 2004 where he developed and managed research programs in gene finding, comparative genomics, and shotgun fragment assembly including the development of the Celera Assembler for assembling the human genome. He was a Computer Scientist at The Institute for Genomic Research (TIGR) from 1992-1998 developing protein homology search, multiple sequence alignment, and shotgun fragment assembly algorithms.

JCVI is one of three NIAID Genome Centers for Infectious Disease (GCID) providing genome sequencing, genotyping, and analysis in response to arising infectious disease issues as a resource to the research community. His group supports the annotation and analysis for prokaryotic projects under this contract. The nature of the GCID prokaryotic projects, where dozens or hundreds of strains or closely related species were to be sequenced, necessitated the development of pan-genome analysis tools. Dr. Sutton has taken a leading role in the development of pan-genome analysis tools.

Research Priorities

Developed the TIGR Assembler to assemble the first genome of a free-living organism, Haemophilus influenza, as well as many more prokaryotic genomes.

Co-developed the Celera Assembler to assemble the Drosophila melanogaster, human, mouse, rat as well as many more eukaryotic genomes. The Celera assembler enabled the shotgun fragment assembly of large eukaryotic genomes revolutionizing the sequencing strategy for large genomes.

Co-developed a method for determining mammalian orthologous genes and their intron/exon boundaries using genome and mRNA data.