An ultrafast and memory-efficient package named BS-SNPer for the exploration of SNP sites from BS-Seq data. Compared to Bis-SNP, a popular BS-Seq specific SNP caller, BS-SNPer is over 100 times faster and uses less memory. BS-SNPer also offers higher sensitivity and specificity compared to existing methods.

BS-SNPer statistics

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BS-SNPer in publication

[…] or ratios, thus preserving information about sequencing depth for each site-sample combination. additionally, recent tools for calling snp genotypes directly from bs reads (e.g., bissnp and bs-snper) can help with constructing kinship/relatedness matrices, although not without error ()., most research on dna methylation to date has focused on humans and a handful of model systems. […]

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