Fusion

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

EDP09888

Predicted protein (53 aa)

Predicted Functional Partners:

EDP06353

Predicted protein (922 aa)

0.510

EDP09887

Predicted protein (614 aa)

0.509

FAP78

Flagellar associated protein (1909 aa)

0.506

EDP09417

Predicted protein (1527 aa)

0.485

FAP47

Flagellar associated protein (2832 aa)

0.480

EDP09735

Hydin-like protein (4524 aa)

0.477

FAP59

Flagellar associated protein; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, by acting as a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (PubMed-25395538). Together with CCDC40/FAP172 forms a 96-nm-long complex in flagella. This complex does not act as a physical ruler, but rather act as a negative regulator for radial spokes- the complex lays along specific protofilaments, masking radial spoke binding sites and allowin [...] (894 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

DHC8

EDP06353

EDP04582

EDP06353

Dynein heavy chain 8

Predicted protein

0.625

DHC8

EDP09417

EDP04582

EDP09417

Dynein heavy chain 8

Predicted protein

0.475

DHC8

EDP09735

EDP04582

EDP09735

Dynein heavy chain 8

Hydin-like protein

0.720

DHC8

EDP09887

EDP04582

EDP09887

Dynein heavy chain 8

Predicted protein

0.475

DHC8

EDP09888

EDP04582

EDP09888

Dynein heavy chain 8

Predicted protein

0.475

DHC8

FAP47

EDP04582

EDP04683

Dynein heavy chain 8

Flagellar associated protein

0.715

DHC8

FAP59

EDP04582

EDP04876

Dynein heavy chain 8

Flagellar associated protein; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, by acting as a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (PubMed-25395538). Together with CCDC40/FAP172 forms a 96-nm-long complex in flagella. This complex does not act as a physical ruler, but rather act as a negative regulator for radial spokes- the complex lays along specific protofilaments, masking radial spoke binding sites and allowin [...]

0.694

DHC8

FAP78

EDP04582

EDP03446

Dynein heavy chain 8

Flagellar associated protein

0.694

DHC8

FAP99

EDP04582

EDP03844

Dynein heavy chain 8

Flagellar associated protein

0.421

EDP06353

DHC8

EDP06353

EDP04582

Predicted protein

Dynein heavy chain 8

0.625

EDP06353

EDP09417

EDP06353

EDP09417

Predicted protein

Predicted protein

0.687

EDP06353

EDP09735

EDP06353

EDP09735

Predicted protein

Hydin-like protein

0.667

EDP06353

EDP09887

EDP06353

EDP09887

Predicted protein

Predicted protein

0.647

EDP06353

EDP09888

EDP06353

EDP09888

Predicted protein

Predicted protein

0.510

EDP06353

FAP148

EDP06353

EDP06430

Predicted protein

Flagellar associated protein

0.629

EDP06353

FAP47

EDP06353

EDP04683

Predicted protein

Flagellar associated protein

0.659

EDP06353

FAP59

EDP06353

EDP04876

Predicted protein

Flagellar associated protein; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, by acting as a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (PubMed-25395538). Together with CCDC40/FAP172 forms a 96-nm-long complex in flagella. This complex does not act as a physical ruler, but rather act as a negative regulator for radial spokes- the complex lays along specific protofilaments, masking radial spoke binding sites and allowin [...]

0.694

EDP06353

FAP78

EDP06353

EDP03446

Predicted protein

Flagellar associated protein

0.695

EDP06353

FAP99

EDP06353

EDP03844

Predicted protein

Flagellar associated protein

0.683

EDP09417

DHC8

EDP09417

EDP04582

Predicted protein

Dynein heavy chain 8

0.475

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Network Stats

Network Stats analysis is still ongoing, please wait ...

Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: