Marie Skepö, Associate Professor and Deputy Head of the Division

Grant for Neutron Research awarded by NordForsk

Marie Skepö (PI), has in collaboration with Lise Arleth and Kresten Lindorff-Larsen at University of Copenhagen, and Jens Preben Morth at University of Oslo, been awarded 6.8 MNOK for studying the structure of membrane proteins under solution conditions. The aim is to understand how the lipid environment influences the activity of membrane proteins, using the active transporter MgtA as benchmark system, and to investigate the dynamic fluctuations between lipid and protein in solution, utilising neutron and X-ray scattering in combination with computer simulations.

Adsorption of polyelectrolyte-like proteins to silica surfaces and the impact of pH on the response to ionic strength. A Monte Carlo simulation and ellipsometry study. K. Hyltegren, and M. Skepö. Journal of Colloid and Interface Science 2017.

Molecular Dynamics Simulations of Intrinsically Disordered Proteins: On the Accuracy of the TIP4P-D Water Model and the Representativeness of Protein Disorder Models. J Henriques, and M Skepö. Journal of Chemical Theory and Computation 2016 DOI: 10.1021/acs.jctc.6b00429.