Tiss®-IMAC

Nonwoven nanofibre membrane with IMAC technology

High concentration of special metal-based groups for Immobilized Metal ion Affinity Chromatography (IMAC). Tiss®-IMAC membranes allow histidine-tagged biomolecules to be specifically retained. Elution of the protein of interest can be carried out by changing the pH, or adding a competitive molecule, such as imidazole.

Highlights

New format for IMAC technology based materials. Membrane made of nanofibers easier to use than traditional gels or particles suspensions.

Available with different metals attached for the purification of a broad variety of His-tagged proteins: Co, Ni, Cu and Fe.

Highly specific. No retention of undesired substances.

One step purification.

Minimal metal leaching.

Applications

Purification of recombinant Histidine- tagged proteins.

Competitive edge

The nanostructured nature of Tiss®-IMAC membranes allows to take advantage of a very high specific surface area thus enhancing the retention capacity of these membranes. Moreover, NanoMyP® is the only company that provides this type of membranes as they are based on an exclusive technology developed by the company.