Brief Summary

The purpose of this pilot project is to test whether a home-based eccentrically-biased exercise protocol during the 3-6 month period following hip fracture can mitigate the impairments typically seen in this needy population. Further, we will characterize changes in muscle composition following hip fracture. The specific aims of this project are as follows:

Aim 1. Determine the impact of 3 months of MOVE, initiated at 3 months after hip fracture on physical function.

Hypothesis: MOVE will have a greater effect on physical function (as measured by modified PPT score) than usual care at 3 and 6 months post-surgery

Hypothesis: MOVE will have a greater effect on physical function (as measured by 6-minute walk performance) than usual care at 3 and 6 months post-surgery.

Hypothesis: MOVE will improve muscle quality (force/unit area of muscle) between 3 and 6 months post-surgery to a greater extent than usual care

Exploratory Aim. Characterize muscle size and composition, and the balance between anabolic and catabolic cellular signaling in the muscle 3 months following hip fracture and following 3 months of MOVE or usual care.