comment:

Retinal gliosis (
Figure 2
, compare to normal in
Figure 1
), the proliferation of astrocytes, Müller cells, and/or microglia, can occur in various retinal layers with focal to diffuse distribution. It is characterized by increased numbers of glial cells in the retina. Retinal gliosis can occur as a primary change (generally of uncertain etiology) or as a feature to other retinal lesions (e.g., degeneration).

recommendation:

When occurring as a primary change, retinal gliosis should be diagnosed and assigned a severity grade. When retinal gliosis occurs as a morphologic feature or reactive sequela of another pathologic process (e.g., retinal degeneration), it should not be diagnosed separately (unless warranted by severity), but should be described in the pathology narrative.