This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated.

Protein Function

RAP2B has several biochemical functions, for example, GDP binding, GTP binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RAP2B itself. We selected most functions RAP2B had, and list some proteins which have the same functions with RAP2B. You can find most of the proteins on our site.

Interacting Protein

RAP2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAP2B here. Most of them are supplied by our site. Hope this information will be useful for your research of RAP2B.

RUNDC3A; CAMK2B; RASSF5; VCAM1; pi3p; FN1; MME

RAP2B Related Articles

Paganini, S; Guldetti, GF; et al. Identification and biochemical characterization of Rap2C, a new member of the Rap family of small GTP-binding proteins. BIOCHIMIE 88:285-295(2006).