The rear I/O ports consist of keyboard/mouse PS2 jacks, a clear CMOS button, analog and optical SPDIF outputs, IEEE 1394 FireWire, gigabit NIC, audio block, six USB 2 ports and one USB 3 port with an extra USB 3 port available internally. The two USB 3 ports are provided by the NEC 720200F1 controller located in its usual spot just to the right of the audio block. A Realtek RTL811E provides the Gigabit Ethernet jack while a VIA VT6315N supplies the FireWire. A Fintek F71889ED allows for hardware voltage, fan speed and temperature readings.

The 8-channel HD audio is courtesy of the Realtek ALC892 while a Realtek RTM880N-793 does clock generation. The AMD SB710 provides up to 12 USB 2.0 ports, although only 10 are present on the Fuzion; the six external rear and four via internal header. It also supplies the six SATA 3Gb/s (black connectors) while a Marvell 88SE9128 adds another two SATA 6Gb/s (white connectors). MSI Military Class components use aluminum core solid capacitors, ferrite core icy chokes and tantalum core Hi-C (highly-conductive) polymer caps. This gives the MSI boards a rated 10-year lifetime expectancy.