Mechano growth factor (MGF) is a recently discovered splice variant of IGF-1 or insulin growth factor-1. This is known as IGF-1ec in humans and 1GF-1Eb in rats. This peptide is named as MGF because its RNA form is expressed in the muscle tissues as a response to damage or overload. The C-terminal peptide of MGF is a critical region as the peptide’s alternative splicing area.

How does PEG-MGF works?

1) MGF contains an E domain as such; it is able to act independently on the muscles.

It also produces varying effects due to its ability to induce IGF-1 differentiation and promote mGF satellite cell proliferation. MGF was thought to play several physiological roles because failure of MGF expression leads to age-related loss of skeletal function.

2) It also has neuroprotective properties to which it is able to protect facial neuronal cells after nerve damage.

3) MGF also triggers new protein synthesis.

After the initial splicing of insulin growth factor-1 into MGF, the production turns towards insulin growth factor-1Ea release from the liver. This also increases synthesis of proteins. Over the recovery and regrowth of muscles, the release of IGF-1 splice variants is thought to be the major anabolic mechanism to which the body is producing new muscle. Since PEG-MGF is an injectable peptide, anecdotal evidence has shown that injection of this peptide causes localized muscle growth.

How much PEG-MGF should you take?

You may inject it subcutaneously an hour or 2 before training to mimic the physiologic secretion of IGF 1.

Since Pegylated MGF is considered to be more bioavailable, you will only need to inject it to your body 2 to 3 times a week. PEG MGF remains to be effective few days after self-administration.

What are the benefits of PEG-MGF use?

PEG-MGF has the ability to improve the release of IGF-1 as well as protein synthesis which can help in improving muscle growth amongst its users. It could also promote reduction of fat mass in the body whilst improve immune system, strengthen bone and skin, decrease cholesterol level, increase endurance and improve recovery after injury. Several studies have also shown that unlike other drugs used to increase body and muscle mass gains, PEG-MGF has not caused any serious side effects.

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Related Peptides List:

Polypeptide Hormones

Name

CAS

CJC1295 without DAC(Mod GRF 1-29 )

863288-34-0

CJC1296 with DAC

863288-34-0

Hexarelin

140703-51-1

MGF

/

PEG MGF

/

MT-1

75921-69-6

MT-2

121062-08-6

GHRP-2

158861-67-7

GHRP-6

87616-84-0

Ipamorelin

170851-70-4

Sermorelin

86168-78-7

Oxytocin

50-56-6

TB500

77591-33-4

Pentadecapeptide BPC 157

/

AOD 9604

221231-10-3

Triptorelin

57773-63-4

Tesamorelin

218949-48-5

DSIP

62568-57-4

Selank

/

PT141

189691-06-3

Gonadorelin

34973-08-5

Epitalon

307297-39-8

Follistatin 344

/

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