Ariana Grande was one of the many celebrities who took to social media after learning of the Las Vegas attack. Photo: AP

Many other celebrities also called for tougher gun ownership restrictions.

Tagging US President Donald Trump and Speaker of the House of Representatives Paul Ryan, singer Lady Gaga encouraged politicians to "act quickly".

"Blood is on the hands of those who have power to legislate," she tweeted.

"Sensible gun control NOW," actress Alyssa Milano tweeted, adding her voice to the outpouring of grief.

Singer Rihanna described the event as a "horrific act of terror".

Other celebrities simply expressed sorrow for those affected.

Singer Taylor Swift, who found fame in the country music scene, tweeted there were "no words to express the helplessness and sorrow [her] broken heart feels for the victims in Vegas and their families".