Additional file 3.

Volcano plots. Log2 ratios and p-values for the comparison of untreated HaCaT cells at 4 hours compared
to 2 hours, 12 hours compared to 2 hours, and 12 hours compared to 4 hours were calculated
based on the gene expression measured. Displayed are the -log10(p-value) against log2 ratio for the respective comparisons and the different normalization methods used.
The blue line represents a loess-curve fitted to the values.