In February 1802, she was a twenty-nine-year-old spinster when she married widower James Van Ingen at the Albany Presbyterian church. A year earlier, Van Ingen had buried his second wife - Gertrude's slightly older sister. She then gave birth to Van Ingen children in 1806 and 1809.

Moving a couple of times, these Van Ingens finally settled at 250 North Market Street in a townhouse fit for the family of a civic leader.

Gertrude Schuyler Van Ingen died in December 1825. She had lived fifty-three years. Van Ingen survived until 1843.