Please notice!
This website uses cookies to provide necessary site functionality and improve your online experience. By using this website, you agree to the use of cookies as outlined in the
Privacy Statement
.

As a global market leader with numerous subsidiaries and distributors, Miltenyi Biotec is
committed to providing our customers around the world with the highest quality products.
In addition to direct selling in more than 20 countries in North America, Europe and
Asia/Pacific, Miltenyi Biotec also provides support for our customers through an
extensive distributor network covering dozens of additional countries.

As a global market leader with numerous subsidiaries and distributors, Miltenyi Biotec is
committed to providing our customers around the world with the highest quality products.
In addition to direct selling in more than 20 countries in North America, Europe and
Asia/Pacific, Miltenyi Biotec also provides support for our customers through an
extensive distributor network covering dozens of additional countries.

Anti-Embigin antibodies, mouse

Clone REA501 recognizes the mouse embigin antigen, a single-pass type I membrane protein, which is also known as teratocarcinoma glycoprotein Gp-70. Embigin is a developmentally expressed protein that is a member of the immunoglobulin superfamily class of cell adhesion molecules (CAMs). It is strongly expressed in mouse embryos between five and nine days of gestation but only weakly in adult organs. Embigin plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, embigin promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting the terminal Schwann cell number or their morphology.

Figure 1

Splenocytes from C57BL/6 mice were stained with Anti-Embigin antibodies or with the corresponding REA Control antibodies (left images) as well as with CD45R (B220) antibodies. Flow cytometry was performed using the MACSQuant

®

Analyzer. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence.