Macular edema

Macular edema occurs when fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken and swell (edema). The swelling may distort a person's central vision, because the macula holds tightly packed cones that provide sharp, clear, central vision to enable a person to see detail, form, and color that is directly in the centre of the field of view.

Causes of macular edema

The causes of macular edema are numerous and different causes may be inter-related.

It is commonly associated with diabetes. Chronic or uncontrolled diabetes type 2 can affect peripheral blood vessels including those of the retina which may leak fluid, blood and occasionally fats into the retina causing it to swell.

Age-related macular degeneration may cause macular edema. As individuals age there may be a natural deterioration in the macula which can lead to the depositing of drusen under the retina sometimes with the formation of abnormal blood vessels.

Macular edema

Macular edema occurs when fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken and swell (edema). The swelling may distort a person's central vision, because the macula holds tightly packed cones that provide sharp, clear, central vision to enable a person to see detail, form, and color that is directly in the centre of the field of view.

Causes of macular edema

The causes of macular edema are numerous and different causes may be inter-related.

It is commonly associated with diabetes. Chronic or uncontrolled diabetes type 2 can affect peripheral blood vessels including those of the retina which may leak fluid, blood and occasionally fats into the retina causing it to swell.

Age-related macular degeneration may cause macular edema. As individuals age there may be a natural deterioration in the macula which can lead to the depositing of drusen under the retina sometimes with the formation of abnormal blood vessels.

In fact, myopia progression is a back of the eye disease as we highlighted earlier, and this maybe the first one of the very few times we are treating a back of the eye disease and we have a front of the eye approach for that, because as you know we treat macular degeneration and DiabeticMacularEdema with anti-VEGF, but those actually require intravitreal in the eye injections....

While suprachoroidal CLS-TA is being studied as a monotherapy in patients with macularedema associated with non-infectious uveitis, Clearside is also studying suprachoroidal CLS-TA together with an intravitreal anti-VEGF agent in two other retinal vascular diseases, retinal vein occlusion or RVO and diabetic macularedema, or DME, both of which have a high vascular endothelial growth factor response to their diseases....

CAMBRIDGE, Mass ... (NASDAQ... The initial focus is on inhibitors of plasma kallikrein, which is an important component of the body’s inflammatory response and which, in excess, can lead to increased vascular permeability, edema and inflammation. KalVista has developed a proprietary portfolio of novel, small molecule plasma kallikrein inhibitors initially targeting hereditary angioedema (HAE) and diabetic macularedema (DME) ... CONTACT ... KEYWORD....

I maintain that the prospects for the biopharmaceutical industry are extremely favorable, driven by new drug discovery in oncology, hematology and inflammatory diseases ...Gilead (GILD) reset Hepatitis C revenue expectations earlier this year to approximately 18% of the corporate total ... Eylea could benefit significantly from approval for non-proliferative diabetic retinopathy in patients without diabetic macularedema (DME) ... Disclosure ... ....

Opthea announced that its Phase 1b trial of OPT-302 in diabetic macularedema or DME met its primary objective and that they dosed the first patient in a Phase 2a randomized controlled trial evaluating OPT-302 in patients with persistent center involved DME....

AeriePharmaceuticals, Inc ...Eastern Time in Boston, MA. Mr. Rubino will provide an Aerie overview and business update ... A replay of the webcast will be available for 10 business days. About Aerie Pharmaceuticals, Inc ... Aerie continues to focus on global expansion and the development of additional product candidates and technologies in ophthalmology, including for wet age-related macular degeneration and diabetic macularedema ... SOURCE ... Media.....