Probably not, but it really depends on what you are trying to do, and the processor you are trying to do it on.

If you have a large number and you have to add it in pieces, one byte or word at a time, when you start with the lowest byte or word you have to do one of two things, either add without carry, or first execute an extra instruction to clear the carry and then you can add with carry.

The 6502 microprocessor used in the original Apple II computer only had one add instruction, add with carry. So you always had to put an instruction to clear the carry before the addition of two byte values, or of the first bytes of a multibyte addition.