SAM-e (S-Adenosyl-Methionine) is a dietary supplement that has been clinically shown to promote and support joint health and comfort as well as emotional well-being.

SAM-e is popular in Europe where doctors have administered it for over 20 years. The benefits of SAM-e have been demonstrated by its long term commercial use.

Short and long-term clinical studies show that SAM-e is a very safe and non-toxic product in levels of supplementation of up to 1,600 mg a day (8 caplets).

SAM-e is a naturally occurring compound that serves as a major source for the production of chemicals in the brain and protects DNA from the genetic mutations associated with aging and disease.

SAM-e has been used in clinical studies to treat depression, dementia, demyelination diseases, liver disease, schizophrenia, arthritis and other conditions.

SAM-e has been confirmed by several studies to be more effective in the treatment of depression than traditional pharmaceutical anti-depressants.

SAM-e can increase the levels of the important neurotransmitters: serotonin, dopamine, norepinephrine and phosphatdylserine.

SAM-e is used to counteract depression and anxiety during the detoxification of drug dependent patients.

SAM-e is used in Europe in the treatment of alcohol related liver damage and cirrhosis. SAM-e also helps to inactivate estrogens that cause liver damage and promotes bile flow to aid in the digestion of fat.

SAM-e promotes cartilage and the formation of connective tissue in joints, while a deficiency of SAM-e in the joints can result in the loss of integrity of cartilage.