The unhealthiest item on the McDonald’s menu is the “Big Breakfast with Hotcakes and Large Size Biscuit.” It has a whopping 1,150 calories, 60 grams of fat, 20 grams of saturated fat, 17 grams of sugar, 575 milligrams of cholesterol, 116 grams of carbohydrates, and 2,260 grams of sodium.