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Complement Component 4 Binding Protein, beta ELISA Kits (C4BPB)

On www.antibodies-online.com are 10 Complement Component 4 Binding Protein, beta (C4BPB) ELISA Kits from 6 different suppliers available. Additionally we are shipping C4BPB Antibodies (45) and C4BPB Proteins (6) and many more products for this protein. A total of 71 C4BPB products are currently listed.

C4BPB/C4BPA may not confer susceptibility to schizophrenia among Han Chinese

Binding of complement inhibitor C4b-binding protein to a highly virulent Streptococcus pyogenes M1 strain is mediated by protein H and enhances adhesion to and invasion of endothelial cells.

crystallographic data on the structure of CD11c (show ITGAX ELISA Kits)/CD18 (show ITGB2 ELISA Kits) and prediction of the secondary structure of the C4BP (show C4BPA ELISA Kits) oligomerization domain, we show that epitopes bound by KIM185 in these proteins are unlikely to share any major structural similarity.

Since FI requires cofactors for its activity we also investigated the binding of purified cofactors C4BP (show C4BPA ELISA Kits) and FH and found acquisition of both proteins, which retained their activity in FI mediated degradation of C3b and C4b (show C4B ELISA Kits).

C4BPB Antigen Profile

Antigen Summary

This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.