Effectiveness of dabigatran etexilate for thromboprophylaxis of mechanical heart valves.

Dabigatran has been shown in this promising study to be an effective alternative to warfarin in patients with atrial fibrillation, and it is very interesting to compare dabigatran with warfarin for mechanical valve patients. Unfortunately, dabigatran cannot currently be used in place of warfarin for this purpose, but the situation will be changing when the factor Xa (FXa) inhibitor antidote becomes commercially available.

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