Willis continues to tend to Rox´s medical needs in San Diego and Leanne and Max´s father go searching for Ariel. Also, when Noa reveals to Mario she wants to take a job offer in Philadelphia, and Campbell offers Mario the attending position at Angels, they realize their career choices will mean ending their relationship.

Regina is surprised to find herself needed by Drizella, who is searching for magic. But when a brutal truth is revealed, it could lead Drizella down a dangerous path. In Hyperion Heights, Roni seeks Weaver´s help in finding answers, and Tilly offers Rogers some intriguing advice concerning Eloise Gardener.

With the clock ticking, Desna is scrambling to get out of her worst trouble yet. Determined, she goes searching for the truth with her crew right behind her, save for Jennifer, who is learning how to cope as a Dixie Mafia wife. When Desna´s sleuthing hits pay dirt, she goes to the only person who can save her. Time is running out.

Victims in California have the BAU searching for an UnSub who may have witnessed abuse as a child. Meanwhile, Kate shows parental concern when her niece, Meg, makes a date with a friend to meet a boy they met online.

Picking up after the last event series´ cliffhanger, Mulder and Scully learn that they aren´t the only ones desperately searching for their long-lost son, William. The very fate of the world may depend on it.

Paige deals with Jake´s impending move to Austin, and a revelation about Cassie fractures their friendship. Meanwhile, Rainer starts searching for his real father, but he´s thrown into a tailspin after he puts the pieces together. Later, Jordan tries to mend his relationship with Tangey, who feels betrayed by his secret. But when he shares information about his past, she considers forgiving him.