"Defensively we did some good things," Graves said. "But you can't expect to shoot 25 percent and beat anybody, let alone one of the best teams in the country."

Stanford held Gonzaga to 1-of-14 shooting in the opening seven minutes, and Greenfield made three 3-pointers, as the Cardinal built a 17-5 lead.

Greenfield hit her fourth 3-pointer with 8:12 left in the first to lift Stanford to a 23-5 lead. Gonzaga was 2-of-22 from the floor at that point, while Stanford was 9-of-17.

Palmer scored a pair of baskets for Gonzaga to cut Stanford's lead to 25-9.

Stanford's shooting cooled off and a basket by Karr cut the Cardinal advantage to 14. Ogwumike scored and Tinkle hit a 3-pointer to lift Stanford of a 32-16 halftime lead.

Gonzaga shot just 17.9 percent (7-of-39) in the first half, and did not attempt a free throw.

The teams traded baskets through the first 10 minutes of the second half, and Stanford gradually extended its lead. Greenfield's sixth 3-pointer gave the Cardinal a 52-28 lead with 10 minutes left in the game. Gonzaga did not threaten after that.

The game featured a matchup of sisters Joslyn Tinkle, a senior at Stanford, and Elle Tinkle, a freshman at Gonzaga. Their father is Montana head coach Wayne Tinkle, who wore a shirt with "Gonzford" written on the front.

"It's a special feeling for them to watch their daughters out there and at this level," Joslyn said. "It was extremely fun."

Joslyn Tinkle had 16 points and eight rebounds. Elle finished with two points and 3 rebounds.

Stanford is coming off an 87-38 win at UC Davis in which they held the Aggies to 18 percent shooting. Stanford improved to 5-0 against Gonzaga.

Stanford's last loss was in the semifinals of the NCAA tournament national semifinals to Baylor.

Gonzaga's only other loss this season was to No. 7 Louisville. This is the second time they have played the No. 1 team in the nation, losing at Tennessee in 2007.