Thyrotropin Releasing Hormone Receptor (TRHR) What is lean body mass (LBM)? LBM is the amount you weigh if you subtract your fat content, for many sports having a good LBM is key to success as it can increase power to weight and improve aesthetics (bodybuilding). Did you know that genetics actually impact LBM? One gene in particular called TRHR can actually cause variations of up to 6lbs natural difference in LBM to multiple populations, and is recognised as an important gene for LBM variance and metabolism.

Myostatin-related muscle hypertrophy is a genetic condition that is characterised by increased skeletal muscle size and a reduced bodyfat (the perfect condition for a bodybuilder). Myostatin-related muscle hypertrophy is not known to cause any negative medical issues, unless you class increased strength as one. The only way to truly be diagnosed is with genetic testing, as myostatin-related muscle hypertrophy is caused by mutations in the gene MSTN, those with a mutation in one copy of the gene have increased muscle bulk and to some extent increased strength, those with a mutation in both copies of the gene will have significantly superior strength and far increased muscle size. Side Note: Induced myostatin-related muscle hypertrophyGenetic editing has been conducted in other animals such as pigs and beagles to induce the condition. The aim of this research is to perhaps help those who suffer with muscle dystrophy and neuromuscular diseases.

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