NIPT Test

PrenatalSAFE®is a Non-Invasive Prenatal test which, by analysing the free circulating fetal DNA isolated from a sample of maternal blood, provides6 levels of information in Pregnancy.The NIPT allows for the detection of aneuploidies and microdeletion syndromes, from the most common to the rarest, structural alterations in all the chromosomes of the fetus and the presence of mutations related to serious genetic diseases.

Home visits available for an additional fee of £ 25 within a 20 mile radius of Scan Centre . A voucher will be given for your free reassurance scan at time to suit you.

PrenatalSAFE® 3 – £ 400

For screening of aneuploidies such as Downs, Edwards, Patau with a Dating Ultrasound Scan Included

Genesafe Facilitates Early Diagnosis Of Single-Gene Disorders.The First Non-Invasive Prenatal Test that Screens Multiple Genes For Mutations Causing Severe Genetic Disorders In The Foetus From £1000

GeneSafe works as a complementary screen to traditional and genome-wide NIPT PrenatalSafe KARYO. GeneSafe screens for several life-altering genetic disorders that are not screened with current NIPT technology, allowing for a more complete picture of the risk of a pregnancy being affected by a genetic disorder.

All pregnant women regardless of age are at equal risk of the genetic conditions screened by GeneSafe. Although the occurrence of each disorder is relatively rare, the cumulative rate of these conditions (~1 to 600) is similar to that of Down Syndrome, in younger women.

GeneSafe ™ De Novo – £ 1000

This test screens for 44 severe genetic disorders due to de novo mutations (a gene mutation that is not inherited) in 25 genes.

Many disorders screened with GeneSafe De Novo are not typically associated with abnormal prenatal ultrasound findings (especially in the first trimester), or may not be evident until late second/third trimester, when confirmatory invasive testing can pose a risk of pre-term birth, or baby’s health after delivery.

GeneSafe™ Complete – £ 1500

This test screens for both inherited and de novo single-gene disorders and represents a combination of the tests GeneSafe Inherited and GeneSafe De Novo providing a complete picture of the pregnancy risk.

For More details please Visit https://www.genesafe.co.uk/ for more informations

FREQUENTLY ASKED QUESTIONS

PRENATALSAFE test is a non-invasive prenatal test (NIPT) that offers the reassurance of knowing in the early stages of pregnancy, as early as 10 weeks, that your baby is at low risk of Down Syndrome (Trisomy 21), Edwards Syndrome (Trisomy 18), and Patau Syndrome (Trisomy 13). Other tests that are commonly requested are sex chromosome linked conditions such as Klinefelter syndrome and Turner syndrome. (Please discuss with your healthcare provider which Downs syndrome test is right for you). The NIPT test does not assess risk for mosaicism, partial trisomies or translocations. The test will provide accurate answers when they matter most—simply, safely, sooner.

Your baby’s cell free DNA can be detected circulating in your blood and so it requires a simple blood test, which is then sent to GENOMA Genetic’s labs , analysed and the results returned within 1 week. You will also be required to have an ultrasound scan prior to the blood test to check the viability of your pregnancy.

Although it’s not 100% conclusive, PRENATALSAFE test is highly accurate. The NIPT test identifies in singleton pregnancies more than 99% of fetuses with Trisomy 21, 98% of fetuses with Trisomy 18, and 98% of fetuses with Trisomy 13, and 95% of fetuses with Turner Syndrome. X and Y analysis provides >99% accuracy for fetal sex. Accuracy for detecting other sex chromosome anomalies varies by condition. The risk of requiring further testing such as CVS or Amniocentesis after a PRENATALSAFE NIPT is dramatically reduced.

The PRENATALSAFE test is able to deliver a much higher accuracy than NHS tests giving you greater peace of mind. It’s totally non-invasive, posing minimal risk to mother or baby, can test for more than just Down Syndrome and can be carried out as early as 10 weeks pregnant. NHS Down Syndrome tests are typically undertaken via a nuchal translucency ultrasound between 11 and 14 weeks. NIPT test can only estimate the risk of your baby having Down’s, it can’t tell you for sure either way. For example, if your result is one in 1,000, this means that for every 1,000 babies with your level of risk, one will have Down’s syndrome. A risk of one in 150 or less is considered high. If for some reason the scan cannot be completed, expectant mothers are offered a blood test between 14 and 20 weeks of pregnancy, which is less accurate than the nuchal test. Further testing such as CVS and amniocentesis are invasive and have risk factors associated with them.

Once you have seen your Healthcare Professional and had your scan then a simple blood sample is taken from the expectant mothers arm to be sent to Eurofins labs for processing which will take less than 1 week. Results are sent to the healthcare professional to forward to patients.