Tartt got hurt tackling 270-pound tight end Tony Niklas early in the second quarter of Sunday’s 20-10 loss to the Arizona Cardinals.

So ends what had been a solid season by Tartt, a 2015 second-round draft pick. A third-down stop highlighted his three tackles Sunday, which raised his season total to 54. He was on pace to easily eclipse his totals of 66 and 61 tackles his first two seasons.

Replacing Tartt on Sunday and the foreseeable future was rookie Adrian Colbert, whose best play came when he broke up a deep pass by Cardinals quarterback Drew Stanton.

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"Adrian’s done a good job," coach Kyle Shanahan said. "One play, the quarterback tried to look him off, they threw a go-route and Adrian showed very good range to break it up. I’ve seen him play physical.

"… With Tartt’s broken arm, sounds like he’s going to have more opportunities, so hopefully he continues to get better."

The 49ers have put 17 players on injured reserve since training camp.

Tartt seized the starting strong safety spot once Eric Reid sustained a Week 2 knee injury, and Tartt started Sunday at free safety in place of Jimmie Ward, his high school teammate who went on IR last week with his own fractured forearm.

— Before the 49ers finally pried Jimmy Garoppolo away from the Patriots last week, general manager John Lynch reportedly aimed even higher. After all, Bill Belichick made it clear that New England’s backup quarterback was off-limits.

So when Lynch inquired about Garoppolo and was rebuffed, he called Belichick back to ask about trading for Tom Brady, according to Jay Glazer of Fox Sports.

"Belichick just said, ‘What did you just ask me?" Glazer reported. "(Lynch) said, ‘I’m asking if you’d trade us Tom Brady, (since) you said Garoppolo is off-limits. (Belichick) said, ‘Did you just ask me if I’d trade Tom Brady? … Did you just ask if I’d trade the greatest quarterback of all time. And John said, ‘So is that a no?’"

"I didn’t see Carlos throw a punch. I don’t know exactly what he did," Shanahan said. "I did see him get punches get thrown at him. I did see him get knocked over a couple times. I really loved how he went and got our quarterback’s back."

— Reid’s return from linebacker to safety paid off with an end-zone interception 2:56 before halftime in coverage against Jermaine Gresham. It was Reid’s second interception since 2015; he had four in his first season and three in 2014.

"It was a tendency that we knew, so great job by our defensive quality control guys and assistant coaches of getting us that play," Reid said. "I was just able to make a play on what we practiced." Reid also had a quarterback hit, a pass breakup and four tackles.

— Beathard went deep for Marquise Goowin on consecutive series, and it paid off the second time with a 55-yard reception to the Cardinals 27-yard line. That set up Robbie Gould’s 42-yard field goal to open the second quarter.

But Goodwin mourned over his season-long trend of dropping passes when open. "I just have to do better, especially with Pierre (Garçon) out," Goodwin said. "I can’t be sporadic."

— Defensive lineman Ronald Blair had a fourth-quarter scare to his surgically repaired thumb but returned to action. He was making his season debut and did so as a starter after being activated Saturday off injured reserve.

Blair came off the field to seek treatment on his thumb after a fourth-quarter tackle of Adrian Peterson (37 carries, 159 yards). "He’s got good vision, is one of the greatest of all time and it was an honor playing against him," Blair said. "They just had our number today."

— Injuries to George Kittle and Cole Hikutini thwarted plans to often deploy two tight-end sets to help in pass protection and the overall game plan. Kittle sustained a knee injury on a 14-yard reception on the 49ers’ second snap, and he appeared limited throughout his second-half return. Hikutini was ruled out in the first quarter with a knee injury that is not believed to be of the season-ending variety. Tight end Garrett Celek had one reception for 14 yards.

— Elvis Dumervil and DeForest Buckner, the 49ers’ top pass-rushing threats, watched on the sideline as Drew Stanton threw his second touchdown pass, an 11-yarder to Jermaine Gresham for a 14-3 Cardinals lead 11:04 before halftime.

— The 49ers were 0-for-6 on third down until Kittle’s conversion catch of a 9-yard Beathard pass 2 minutes before halftime. They finished 6-of-17 while the Cardinals were 7-of-16.