U++ is a C++ cross-platform rapid application development suite focused on programmers' productivity without sacrificing runtime performance. Based on strictly deterministic design, it provides a viable alternative to garbage-collected platforms, even for business logic oriented problems.

Chicken is a Scheme compiler that translates most of R5RS Scheme into relatively portable C. It supports fully general tail-call recursion, first-class continuations, and has a very flexible and efficient interface to C and C++. Chicken implements several extensions to the Scheme language: lightweight threads, pattern matching macros, dynamic loading of compiled code, and various object-oriented paradigms, such as TinyCLOS, and others. The library system includes hundreds of convenient modules for practical use.

Erlang is a small concurrent functional programming language developed by Ericsson. It is being used by Ericsson as a systems programming language for large concurrent fault-tolerant distributed systems.

Pike is an interpreted, object-oriented, dynamic programming language with a syntax similar to C. It includes a powerful modules system that, for instance, has image manipulation, database connectivity and advanced cryptography. It is simple to learn, does not require long compilation passes and has powerful built-in data types allowing simple and fast data manipulation.

J2ObjC is a tool from Google that translates Java code to Objective-C for the iOS platform. It enables Java code to be part of an iOS build, as no editing of the generated files is necessary. The goal is to write an app's non-UI code (such as data access or application logic) in Java, which can then be shared by Web apps using GWT, Android apps, and iOS apps. J2ObjC supports most Java language and runtime features required by client-side application developers, including exceptions, inner and anonymous classes, generic types, threads, and reflection. JUnit test translation and execution are also supported.

Steel Bank Common Lisp is a development
environment for Common Lisp, with excellent
support for the ANSI standard: garbage collection,
lexical closures, powerful macros, strong dynamic
typing, incremental compilation, and the famous
Common Lisp Object System (multimethods and all).
It also includes many extensions, such as native
threads, socket support, a statistical profiler,
programmable streams, and more. These are all
available through an integrated, interactive
native compiler which feels like an interpreter.
SBCL is unique in being a multiplatform native
compiler which bootstraps itself completely from
source, using a C compiler and any other ANSI
Common Lisp implementation.

Parrot is a virtual machine designed to efficiently compile and execute bytecode for dynamic languages. It currently hosts a variety of language implementations in various stages of completion, including Tcl, Javascript, Ruby, Lua, Scheme, PHP, Python, Perl 6, APL, and a .NET bytecode translator.