Manny Pacquiao has accused Juan Manuel Marquez of running from him in past fights, insisting he wants the Mexican to stand toe-to-toe this weekend.

Pacquiao and Marquez collide for a fourth time in Las Vegas, determined to settle a rivalry that has already spanned eight years. An initial draw was followed by two Pacquiao victories, but his most recent was hotly disputed.

Speaking 48 hours before the bout, Pacquiao claimed his last three opponents - of which Marquez is one - all refused to stand and fight like men. The Filipino has not finished any of his last five rivals, but insists that is not his fault.

"It just happens that in the last three fights I've fought people who run around - who won't fight me toe-to-toe," Pacquiao told Sky Sports News.

"I expect more action, it's going to be a good fight like the last three, and I'm expecting him to try to prove something and fight toe-to-toe with me.

"I'm very excited for the fight on Saturday. I need to answer all the doubts of Marquez's fans and this fourth fight will be the answer. My focus is on more aggressiveness and if I have the chance to finish the fight I will grab that opportunity and I will finish the fight."

Asked what he has been working on ahead of Saturday's battle, Pacquiao pointed to his weaker right hand, which he now predicts can be as damaging as his favoured left.

"We believe we can bring something new for this fight, I've worked on my right hand and I hope to use it in the fight," he said.

The inevitable question about a future fight with Floyd Mayweather Jr was raised, and Pacquiao reiterated that he has done all he can, including accepting a smaller percentage of the fight purse and agreeing to random drug testing.

"I'd love to fight Floyd Mayweather, I've agreed to anything he wants to make the fight happen. It's up to him. The call is his. I want that fight because that's what the fans want," Pacquiao said.