A profile of the DeMoe family, in which five of six siblings carry one of the rare genetic mutations that cause inherited, early-onset Alzheimer's disease. The family is partnering with University of Pittsburgh doctors to understand the course of early-onset Alzheimer's.

This video is part of the "THE ALZHEIMER'S PROJECT," a presentation of HBO Documentary Films and the National Institute on Aging at the National Institutes of Health in association with the Alzheimer's Association, The Fidelity® Charitable Gift Fund and Geoffrey Beene Gives Back® Alzheimer's Initiative.

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