In Cameron, a group of hunters is attacked by a wild animal, and Charlie Cowley survives but sees his brother Scott dying. Seven years later, his teenage nephew Derek Cowley steals the key of his stepfather s cabin in the isolated Fire Road 13 and travels with four classmates and his friend Sam to spend the weekend having a party with booze and sex. However, they are attacked by a Beast that kills his friends in a sadistic way. Sam and Derek survive, and they suspect that his stepfather Mitchell Toblat is a werewolf. When Charlie meets Derek and Sam, they decide to collect evidence to prove that Mitchell is the Beast and kill him, but Mitchell discovers their plot and chases the trio.