Abstract

Since the introduction of merbaphen as an antisyphilitic agent and a diuretic much attention has been directed to its toxic effects. These have been, in general, indicative of mercurial poisoning, and include stomatitis, diarrhea, and renal irritation; minor toxic symptoms, such as slight fever, chills, malaise, and headaches, are common, but more severe reactions are relatively rare. Marvin has described something resembling a state of shock with chills, sweating, cyanosis, collapse, and occasionally urinary suppression following its use. Deaths have also been attributed to the drug (Redlich) not only when used as a diuretic, but as a remedy for syphilis.