Nevada Cancer Institute , founded in 2002, was the official cancer institute for the state of Nevada from 2003 to 2013, located in Summerlin, Nevada. The Institute became part of the UC San Diego Health System in February, 2012. A non-profit organization, NVCI served patients throughout the greater Las Vegas area, offering full-service clinics in Summerlin, Nevada, and at University Medical Center, in the downtown medical district. The Institute’s mobile screening unit, the Hope Coach, has provided mammography services throughout the state.NVCI has served more than 17,000 patients since opening in 2005. The Institute was dedicated to providing innovative and collaborative cancer care, clinical trials and community education.The Institute closed on January 31, 2013. Wikipedia.

"Jim and I are honored and humbled as recipients of this award from an institution whose work is critical and whose impact is enduring," Heather Hay Murren said. "In a city full of memorials, the Wilson Center is unique as both a remembrance of the past and a pioneer of the future. Since its founding nearly 50 years ago, it has remained the preeminent institution for civil justice – revered around the world."
"The Woodrow Wilson Award for Corporate Citizenship honors corporate leaders who exemplify Woodrow Wilson's commitment to scholarship, public discourse, and the promotion of knowledge both at home and abroad," said Congresswoman Jane Harman, director, president and CEO of the Wilson Center. "Jim and Heather embody these principles. We are delighted to honor their commitment to communities and our greater global society."
Jim Murren is chairman and CEO of MGM Resorts International, a global entertainment company operating in national and international destinations that feature hotel resorts, conference centers, casino and live entertainment venues, restaurants and retail stores. The company opened MGM National Harbor in Maryland on December 8, 2016, and is in the process of developing MGM Springfield in Massachusetts. Murren serves as chairman of MGM China Holdings Ltd., which owns MGM Macau and is developing a resort in Cotai. He also serves as chairman of MGM Growth Properties, a real estate investment trust engaged in the acquisition, ownership and leasing of large-scale destination entertainment and leisure resorts.
Mr. Murren joined MGM in 1998 after spending more than a decade on Wall Street, where he was regarded as a leading analyst in the hotel and gaming industries. His arrival at MGM coincided with a period of dramatic growth for the company, including the acquisitions of Mirage Resorts and Mandalay Resort Group. He steered the company through the financial crisis, deleveraging the enterprise by restructuring debt, maximizing cash flow and certain selected asset sales. He is the visionary behind CityCenter, the unprecedented urban resort destination that opened on the Las Vegas Strip in 2009 featuring the centerpiece ARIA Resort & Casino. Mr. Murren has led the industry in environmentally responsible practices to lower the company's carbon footprint in operations, resorts, restaurants, retail spaces, meetings and conventions.
Heather Hay Murren is a private investor and former managing director and group head of Global Securities and Economics at Merrill Lynch. She retired in 2002 after more than a decade on Wall Street as a highly-respected, celebrated and leading analyst. At a time when the consumer goods industry was undergoing a period of profound transition, Ms. Murren established a reputation for incisive analysis and a willingness to take controversial stances that consistently proved correct. She played key roles in dozens of complex and high-profile Fortune 500 transactions, including Estee Lauder's initial public offering.
In 2002, influenced by a passion for health issues, cancer research and access to high quality healthcare, the Murrens founded the nonprofit Nevada Cancer Institute, a cancer research and treatment center that launched the first-ever clinical trials in Nevada. Ms. Murren served as chairman and CEO and later as a board member until the institute merged with Roseman University in 2013. She was appointed by Congress to serve on the Financial Crisis Inquiry Commission tasked with determining the causes of the financial crisis. "The Financial Crisis Inquiry Report" of the commission's findings was listed on the New York Times bestseller list. She also served the state of Nevada as a member of the Nevada Board of Economic Development, formed in September 2011 by Governor Brian Sandoval. Ms. Murren was appointed and served as a commissioner on the White House Commission on Enhancing National Cybersecurity in 2016. The commission's findings were presented to President Obama in December 2016. She serves on the board of directors of Fidelity National Financial Inc. and on the board of trustees of Johns Hopkins University and the Johns Hopkins University Applied Physics Laboratory.
The Murrens have been ardent supporters of Volunteers in Medicine of Southern Nevada, a non-profit organization that provides medical care and support at no cost to uninsured and underserved residents of Clark County, which has a population of more than 2 million people. They have also provided foundational funding on a Fisher House hotel at the VA Medical Center to serve the families of Nevada wounded warriors receiving care at the Veterans Administration Hospital in Las Vegas.
The Wilson Center (www.wilsoncenter.org), chartered by Congress as the official memorial to President Woodrow Wilson, is the nation's key non-partisan policy forum for tackling global issues through independent research and open dialogue to inform actionable ideas for the policy community.
MGM Resorts International (NYSE: MGM) is one of the world's leading global hospitality companies, operating a portfolio of destination resort brands including Bellagio, MGM Grand, Mandalay Bay and The Mirage. The Company opened MGM National Harbor in Maryland on December 8, 2016, and is in the process of developing MGM Springfield in Massachusetts. MGM Resorts controls and holds a 76 percent economic interest in the operating partnership of MGM Growth Properties LLC (NYSE: MGP), a premier triple-net lease real estate investment trust engaged in the acquisition, ownership and leasing of large-scale destination entertainment and leisure resorts. The Company also owns 56 percent of MGM China Holdings Limited (SEHK: 2282), which owns MGM MACAU and is developing MGM COTAI, and 50 percent of CityCenter in Las Vegas, which features ARIA Resort & Casino. MGM Resorts is named among FORTUNE® Magazine's 2016 list of World's Most Admired Companies®. For more information about MGM Resorts International, visit the Company's website at www.mgmresorts.com.
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— Des Hague, Froozer® Chairman of the Board, and Rich Naha, Froozer® CEO, recently announced that Joseph C. Essa, President of Wolfgang Puck Worldwide, has been appointed to the Board of Directors, effective immediately.
"We are delighted to have Joe join our Board of Directors," stated Des Hague, "and we are confident that Joe will have an immediate positive impact on Froozer®. He will be able to share best practices in navigating our retail channels, accelerating key introductions in the military channel, expanding our broker network in numerous channels and helping us refine our overall position in the market."
As President of Wolfgang Puck Worldwide, Essa's responsibilities include building and leading an executive team as well as the related strategic plan and systems for this successful casual restaurant and consumer product business with annual retail revenues of $250 million.
Prior to joining the Wolfgang Puck Fine Dining Group, Essa worked with restaurateur Pino Luongo in New York City as Vice President of Operations at TOSCORP, Inc., which includes the restaurant concepts Coco Pazzo, Le Madri and Tuscan Square. He also founded and operated two successful restaurants, Assaggio in West Hartford, Connecticut and Café Pasta in Greensboro, North Carolina.
Essa graduated cum laude from Boston College with a bachelor of science in accounting and finance. He is a Certified Public Accountant and is accredited by the National Restaurant Association. His community involvement includes personal work with charitable organizations benefiting Meals on Wheels, Alzheimer's research, Nevada Cancer Institute, Nevada Public Education Foundation and March of Dimes, among others.
"Joe's experience and proven track record in managing global brands is invaluable to Froozer®," stated Naha. "We believe that Joe will truly help to accelerate the growth and relevance of the brand."
"I am honored to join the Froozer® board, and look forward to supporting Rich Naha, his talented team of industry professionals and the very exciting Froozer® product line," said Essa.
About Froozer® - "simple ingredients. real nutrition."
Froozer® products, the official healthy frozen fruit & veggie snack partner of US Speed Skating, represent the pure goodness of freshly harvested fruits & veggies picked at the peak of their ripeness, flash-frozen whole and blended for optimal taste, nutrition and digestion. Natural fruits and veggies in all their glory, nothing added or subtracted, not even a drop of water. Available in three delicious flavors - STRAWBANANA BLISS, TROPICAL SUNSET and BLUE ALOHA - in 6-pack boxes. Look for Froozer® in your local grocery store freezer at select fine retail locations in the Denver Area, including WholeFoods and Alfalfa's, and various select retailers in Arizona, California, Connecticut, Oregon, Washington State, Rhode Island and Alaska, or place your order for a 48-count box at http://www.Froozer.com or http://www.amazon.com to have your Froozer® delivered directly to your home or office.
For more information, please visit http://froozer.com

Uridine phosphorylase (UPP) is a central enzyme in the pyrimidine salvage pathway, catalyzing the reversible phosphorolysis of uridine to uracil and ribose-1-phosphate. Human UPP activity has been a focus of cancer research due to its role in activating fluoropyrimidine nucleoside chemotherapeutic agents such as 5-fluorouracil (5-FU) and capecitabine. Additionally, specific molecular inhibitors of this enzyme have been found to raise endogenous uridine concentrations, which can produce a cytoprotective effect on normal tissues exposed to these drugs. Here we report the structure of hUPP1 bound to 5-FU at 2.3 A resolution. Analysis of this structure reveals new insights as to the conformational motions the enzyme undergoes in the course of substrate binding and catalysis. The dimeric enzyme is capable of a large hinge motion between its two domains, facilitating ligand exchange and explaining observed cooperativity between the two active sites in binding phosphate-bearing substrates. Further, a loop toward the back end of the uracil binding pocket is shown to flexibly adjust to the varying chemistry of different compounds through an "induced-fit" association mechanism that was not observed in earlier hUPP1 structures. The details surrounding these dynamic aspects of hUPP1 structure and function provide unexplored avenues to develop novel inhibitors of this protein with improved specificity and increased affinity. Given the recent emergence of new roles for uridine as a neuron protective compound in ischemia and degenerative diseases, such as Alzheimer's and Parkinson's, inhibitors of hUPP1 with greater efficacy, which are able to boost cellular uridine levels without adverse side-effects, may have a wide range of therapeutic applications.

The present invention relates to the compositions, formulations and methods of treating fatty liver disorders, such as non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) and their sequelae by administration of uridine or a compound that modulates one or more uridine phosphorylases in a subject in need thereof.