Background
Optimal brain function requires the ready availability of brain critical nutrients,
especially during periods of extreme stress. Deficiencies of brain-specific nutrients,
in addition to inadequate calories, may not only substantially contribute to suboptimal
cognition and alertness, but may manifest as severe psychiatric disorders including
adjustment disorders, major depression, impulsive violence and suicide.

The mammalian brain is primarily composed of fats and lipids, usually 60% wet weight.
Approximately 30% of fatty acid pool cannot be made de novo and must be obtained
through the diet and are thus termed essential fatty acids.