Evidence summaries

Summaries of the best available evidence for selected new medicines, off-label use of licensed medicines and unlicensed medicines.

Evidence summaries:

inform national commissioning decisions about medicines, for example by NHS England

provide information for healthcare professionals to inform their decision-making and support the development and updating of local formularies

help inform the public about a medicine and condition to help them make decisions about the medicine

provide information about an unlicensed medicine or off-label use of a licensed medicine that is being considered when there are no suitable alternatives licensed for that situation.

Evidence summaries are NICE advice, they do not include recommendations anddonot constitute formal NICE guidance. The strengths and weaknesses of the relevant evidence are critically reviewed within each evidence summary.