The primary mission of WSTF is to support NASA's Space Station program, and previously the Space Shuttle. As the official Johnson Space Center (JSC) Propulsion Systems Development Facility, WSTF participates in propulsion systems testing, with test expertise in hypergolic propellant handling and training. It was the Shuttle Fleet Leader for testing orbital maneuvering and reaction control subsystems.WSTF Propulsion

The engineers, chemists, and scientists in WSTF laboratories conduct testing of hazardous materials and propellants, air quality, aerospace hardware and ground support equipment, and all materials used in space flight. Standard Testing for ASTM and NASA, as well as ignition and flammability testing is routinely performed.

Oxygen compatibility is a critical issue in space, aircraft, medical, and industrial applications. At WSTF, researchers investigate the effects of increased oxygen concentration on the ignition and burning of materials and components used in these applications. Hazards analyses are performed on materials, components, and systems; and failure analyses determine the cause of fires. Training courses about design and operation of safe oxygen systems are provided by WSTF personnel under the auspices of ASTM. WSTF NASA Oxygen Systems

Since the late 1990s, NASA and a series of subcontractors have been working under the oversight of the New Mexico Environment Department to remediate a large plume of polluted ground water caused by repeated leaks and spills of cleaning fluids and rocket propellants at the site. Remediation has involved the construction of six wells from which the groundwater is pumped; a UV reactor which treats the contaminated water; and four injection wells to inject the cleaned water back into the water table. A second, similar system is currently in the planning stage.