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A Message from President Young.....3 A Message from John Francis.....4 A Message from Steven Roens.....5 Undergraduate Abstracts.....6 Research Posters on the Hill.....78 Utah Conference on Undergraduate Research.....114 Honors Program.....116 Alphabetical Index.....137

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THE UNIVERSITY OF UTAH Static Stretch Induces Parallel Alignment of Endothelial Cell Sprouts in an In Vitro Angiogenesis Model Jacob A. Jensen (Yan-Ting Shiu) Department of Bioengineering University of Utah A better understanding of how mechanical forces influence angiogenic behavior under both physiological and pathological conditions can aid in multiple conditions resulting from irregular vessel growth. Previous work has demonstrated that cyclic stretch does not affect the occurrence nor the length of invasive endothelial cells, however, it does cause the endothelial cells to align perpendicularly to the stretch direction. This investigation conducts similar experiments under static stretch. It is shown that a simple static stretch also does not affect the number and length of endothelial cells during angiogenesis. However, the static stretch had an opposite affect on the orientation of endothelial cell sprouts; it caused alignment parallel to the stretch direction. Yan-Ting Shiu 38