Overview

Pancreatic agenesis is a rare condition that occurs when the pancreas fails to develop before birth. The severity depends on how much functional pancreatic tissue is present. Children with this condition usually have permanent neonatal diabetes mellitus due to a lack of insulin. Pancreatic agenesis can also be associated with abnormalities in other parts of the body. Mutations in the GATA6, PDX1, and PTF1A genes have been found to cause pancreatic agenesis.[1][2][3]

On this page

Basic Information

NetWellness is a consumer health web site that provides information created and evaluated by medical and health professional faculty. Click on the link to read a question in the Ask an Expert section about pancreatic agenesis.

In Depth Information

Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.

Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.

Other Names for this Disease

Congenital pancreatic agenesis

Pancreatic agenesis, congenital

See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.