Q.
I'm getting error 1450 in the event log.
A.
This means that insufficient resources exist to complete a request.
Some versions of NT only allow a program to access a registry key up
to 64k times, after which all accesses to the key fail, producing unpredictable results.
Microsoft recognises this problem, and recommends rebooting.

Prior to Version 5.1f1, the software checked the registry every minute.
For Versions 5.1f1 and above, the software checks registry keys only once.
This may mean rebooting when some program options are changed (adding users, protecting
directories etc will not be affected - no reboot is required).