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International LeagueJustin Wilson, Indianapolis(1-1, 2.19 ERA, 2 G, 2 GS, 12 1/3 IP, 5 H, 3 R, 3 ER, 0 HR, 1 HBP, 7 BB, 14 K)
Wilson took the loss in three of his first four starts this season, including a five-walk performance at Louisville on Monday. The Durham Bulls provided a cure for the Pirates' No. 10 prospect, as Wilson tossed the first 7 1/3 frames of Indianapolis' first no-hitter since 2005. The left-hander, who helped Fresno State clinch the 2008 College World Series, struck out nine and retired 14 batters in a row from the third to the eighth innings to send Durham to its 13th consecutive defeat.Indians' Wilson saves a hitWilson strikes out Rhymes to end the sixthTop prospects: Justin Wilson

Pacific Coast LeagueHeath Hembree, Fresno(0-0, 0.00 ERA, 3 G, 3 SV, 3 IP, 0 H, 0 R, 0 ER, 0 HR, 0 HBP, 0 BB, 1 K)
All a manager can ask of his closer is perfection. Hembree delivered it for Grizzlies skipper Bob Mariano this week, retiring all nine batters he faced to close out three victories. Only one opposing hitter was able to get the ball out of the infield against the 23-year-old right-hander, who began the season as San Francisco's No. 3 prospect. After leading the Minor Leagues with 38 saves in 41 opportunities last season, Hembree has converted five of six chances in his first month in Triple-A.Top prospects: Heath Hembree

Eastern LeagueTyler Cloyd, Reading(1-0, 0.00 ERA, 2 G, 2 GS, 13 IP, 6 H, 0 R, 0 ER, 0 HR, 0 HBP, 3 BB, 12 K)
It's been a wild month for the 24-year-old Cloyd. When Dave Bush was suspended for the start of the season, Cloyd made a spot start for Lehigh Valley on Opening Day. The former 18th-round pick responded by throwing six perfect innings in his Triple-A debut and earning International League Pitcher of the Week honors. Back in Double-A, Cloyd has been almost as good. This week he held Richmond to five hits over seven scoreless innings Tuesday before tossing six one-hit frames at Portland in a no-decision Sunday afternoon. After five starts at two levels this season, the Phillies prospect is 4-0 with a 1.45 ERA and a .200 average against.

Southern LeagueMatt Magill, Chattanooga(2-0, 1.29 ERA, 2 G, 2 GS, 14 IP, 11 H, 2 R, 2 ER, 0 HR, 0 HBP, 5 BB, 13 K)
Magill was ripped for eight runs on seven hits and three walks over three innings April 18 but rebounded this week with a pair of solid outings that earned him his first two Double-A victories. The 22-year-old right-hander allowed a single run over seven innings against both Tennessee on Tuesday and Mobile on Sunday while racking up 13 strikeouts. Magill, who went 11-5 and surrendered 15 homers in the Cal League last season, has given up just one longball in his first five Southern League outings.

Texas LeagueDan Houston, Tulsa(2-0, 0.64 ERA, 2 G, 2 GS, 14 IP, 6 H, 2 R, 1 ER, 1 HR, 0 HBP, 3 BB, 12 K)
Tulsa owns the Texas League's best record at 18-6, thanks largely to its pitching staff, which leads the circuit with a 2.83 ERA. Houston did his part for the cause this week, allowing one earned run on six hits over 14 innings while earning wins over Arkansas on Tuesday and Springfield on Sunday. In his five starts this season, the 25-year-old righty has given up 22 hits in 30 innings for a .204 average against.Drillers' Houston fans seventh

California LeagueNick Maronde, Inland Empire(0-0, 0.00 ERA, 1 G, 1 GS, 7 IP, 3 H, 0 R, 0 ER, 0 HR, 0 HBP, 2 BB, 12 K)
A third-round pick out of the University of Florida last June, Maronde has been strong in his first five full-season outings but has yet to notch a victory. The Angels' seventh-ranked prospect held High Desert -- the top-hitting team in the Cal League -- to three hits while striking out a career-high 12 batters over seven scoreless innings, but the 66ers ultimately fell, 5-3. Maronde leads the Inland Empire staff with 30 strikeouts and saw his WHIP fall to 1.03.Top prospects: Nick Maronde

Carolina LeagueBrandon Workman, Salem(1-0, 0.00 ERA, 1 G, 1 GS, 6 IP, 3 H, 0 R, 0 ER, 0 HR, 0 HBP, 0 BB, 4 K)
Workman's season debut did not go well on April 20, as the 2010 second-round pick gave up four runs on eight hits over 4 1/3 innings in a no-decision at Potomac. The right-hander's first home start, however, was sublime. Workman held Carolina to three hits in six innings and allowed just one Mudcat to reach second base in the 7-2 win. The Texas product struck out four and did not walk a batter as the Sox won the opener of what would be a three-game sweep.Top prospects: Brandon Workman

Florida State LeagueJameson Taillon, Bradenton(1-0, 0.00 ERA, 2 G, 2 GS, 11 IP, 6 H, 0 R, 0 ER, 0 HR, 0 HBP, 2 BB, 10 K)
The Pirates have been understandably cautious with the arm of Taillon, the second overall pick in the 2010 Draft. The right-hander averaged four innings in his 23 starts for West Virginia last season. This week served notice that the training wheels are coming off, as Taillon stifled the Jupiter Hammerheads for 11 scoreless innings over two starts. Sunday's game, in which Taillon earned his first Florida State League victory, was the longest of his career: six three-hit innings. MLB.com's No. 8 prospect has fanned 28, walked four and held FSL hitters to a .169 average in 24 2/3 innings this season.Taillon on his progress as a pitcherNo. 8 prospect: Jameson Taillon

Midwest LeagueSean Murphy, Burlington(1-0, 0.00 ERA, 1 G, 1 GS, 7 IP, 4 H, 0 R, 0 ER, 0 HR, 0 HBP, 0 BB, 13 K)
After struggling to a 6.33 ERA in 15 appearances for Burlington last year, Murphy has been dominant for the Bees this spring. The 6-foot-6 right-hander limited host Fort Wayne to four hits while striking out a career-high 13 batters over seven scoreless innings on Wednesday. Murphy's 31 strikeouts are one shy of the league lead. Last season, the Midwest League hit .328 off the Keystone College product; in 2012, it is managing just .185.

South Atlantic LeagueJose Fernandez, Greensboro(2-0, 0.79 ERA, 2 G, 2 GS, 11 1/3 IP, 7 H, 2 R, 1 ER, 0 HR, 0 HBP, 3 BB, 12 K)
The Marlins made Fernandez the 14th overall pick in last year's Draft and many consider him their top pitching prospect. He showed why this week, striking out eight over six innings and combining with two relievers on the Minor Leagues' first no-hitter of the season. West Virginia managed seven hits off Fernandez on Sunday, but just one earned run as the 19-year-old right-hander improved to 3-0 in five starts. He ranks second in the Sally League with 37 strikeouts in 28 1/3 innings.Top prospects: Jose Fernandez

John Parker is a contributor to MLB.com. This story was not subject to the approval of the National Association of Professional Baseball Leagues or its clubs.