The city of Worcester has cleared the way for final two medical marijuana dispensaries to come into the city after City Manager Edward Augustus issued letters of non-opposition to Mission Massachusetts, Inc. and Medicinal Alternatives, Inc.

Mission Massachusetts will locate a retail and cultivation facility at 640 Lincoln St. and will employ approximately 50 people. Medicinal Alternatives will locate a retail and packaging facility at 1191 Millbury St. and employ approximately 30 people.

The city previously issued letters of non-opposition to Good Chemistry of Massachusetts, Inc. to locate a dispensary at 9 Harrison St. in the Canal District and Prime Wellness Centers, Inc. to locate in the northern part of the city on Pullman Street.

As a condition of receiving the letter, Mission Massachusetts and Medicinal Alternatives have signed community host agreements equivalent to those previously signed by Good Chemistry and Prime Wellness. The deals are worth $450,000 for the city and 2.5 percent of gross sales on an ongoing basis.

By 2019, the four entities operating dispensaries in Worcester will supply approximately 140 jobs, a minimum of $800,000 in annual payments, and a minimum of $50,000 annually to site neighborhoods.

The city's letter is just one part of the approval process for these dispensaries to begin operating, as the ultimate approval must be granted by the Massachusetts Bureau of Health Care Safety and Quality. The bureau has no specific timeline for how long these approves take, and each applicant must pay $31,500 in state fees.