TELOMERE PROTECTORS

TeloVite contains an array of telomere protecting nutraceuticals. All of them are backed by peer-reviewed scientific studies, published in prestigious medical journals. Here are the telomere lengthening evidence-based vitamins, antioxidants and phytonutrients found in TeloVite:

FOLATE, VITAMIN B12 AND LONGER TELOMERES

In July 2009, the USDA Research Center on Aging looked at telomere length, and one of the ingredients in TeloVite called folate. Now the study looked at 195 men, and they found that those men with higher folate levels had longer telomeres. We also matched the folate with vitamin B12, because studies show, when they’re combined it creates an additional pathway to longer telomeres – in humans.

VITAMIN E, VITAMIN A, FOLATE, PREFORMED NIACIN AND CALCIUM

Results from a recent population study suggest that at key micronutrients affect genome stability in human subjects in vivo The results have recently been reported of a cytogenetic epidemiological study of 190 healthy individuals designed to determine the association between dietary intake, measured and genome damage in lymphocytes. The highest tertile of intake of vitamin E, vitamin A, folate, preformed niacin (niacin or niacinamide) and calcium is associated with significant reductions in chromosome breakage or loss.

GREEN TEA EXTRACT

There was an exciting 2010 human study published in the British Journal of Nutrition. The researchers found that the cells of regular tea drinkers may have a younger biological age than cells from non-drinkers. They looked at the ‘telomere’ length of 976 Chinese men aged 65 and over. Here’s what they found:

3 cups per day of green or oolong tea, both derived from the same plant, was associated with significantly longer telomere lengths, which corresponds to, now get this, “approximately a difference of 5 years of life.” That’s 5 added years!

That’s why we made sure that TeloVite contains the amount of antioxidants found in at least three cups of green tea, the amount seen in this human study to promote healthy telomere length.

VITAMIN D

Vitamin D is the hottest vitamin out there today, and here’s a good reason. In a 2007 study from the American Journal of Clinical Nutrition, they looked at 2,160 women, those with higher vitamin D levels had fewer aging-related changes in their DNA. But guess what? They were also more likely to have longer telomeres. In fact, a positive 5 years difference in telomere aging, the same result as the green tea study. With TeloVite, we are combining these ingredients for maximum telomere lengthening.

There’s also a double blind, randomized and placebo-controlled clinical trial, the gold standard for research, published in the International Journal of Obesity in June 2012. They looked at whether vitamin D would positively impact the telomeres of overweight adults.

Here’s what the researchers found, “our data suggest that vitamin D may improve telomere maintenance and prevent cell senescence and counteract acceleration of cellular aging.” Translation: vitamin D kept their cells from decaying and it shut down the cellular damage. In fact, their telomerase activity shot up by nearly 20%!

Remember, telomerase is sometimes called your “fountain of youth” enzyme. That’s why we have the clinically relevant amount of vitamin D in TeloVite — because research shows an association with vitamin D and healthy telomeres.

Vitamin D is thought to play a role in reducing telomere loss through protective actions involving gene expression of several cellular pathways.

THE MULTIVITAMIN

National Institute of Health researchers were the first to report, in a study published in the March 2009 issue of American Journal of Clinical Nutrition, epidemiological evidence that regular multivitamin use was associated with longer telomeres among women.

The study found that when compared to non-users of multivitamins, the women who used multivitamins had an average of 5.1 percent longer telomeres, which can translate to a difference of a potential 9.8 years of age-related telomere loss.

The micronutrients most likely to have an important role in preserving telomeres, wrote the scientists, were vitamins C, D, E and certain B vitamins. Based on previous cell culture and animal studies, the authors stated that the higher dietary intake of vitamins C and E is thought to have made an impact on slowing telomere loss due to protection against free radicals, which cause oxidative stress.

The B vitamins, such as folate and B12, are thought to act on slowing telomere loss by reducing amounts of the unhealthy amino acid homocysteine in plasma.

RESVERATROL

Resveratrol was introduced into the dietary supplement market years ago because it was thought that resveratrol, and other polyphenol compounds from red wine, may contribute to the “French Paradox,” the unexpectedly longer lifespans found in the Mediterranean population, despite a diet that is relatively high in saturated fat.

In-vitro studies suggest that resveratrol is capable of promoting telomerase activity, thereby helping to maintain telomere length. Likewise, resveratrol has also demonstrated an ability to delay cell senescence (cell aging) by its action on telomerase, that healthy lifespan enzyme.

In addition, research has shown that resveratrol significantly extends the lifespan of lower organisms such as the yeast Saccharomyces cerevisiae, the worm Caenorhabditis elegans and the fruit fly Drosophila melanogaster. Other research demonstrated that resveratrol had similar positive lifespan effects on the short-lived fish, Nothobranchius furzeri, also increasing swimming performance, and cognitive performance. Another study has shown that resveratrol improved the health and survival of mice that were on a high-calorie diet.

L-CARNOSINE

Scientific research has demonstrated that L-Carnosine can maintain and actually lengthen telomeres. Due to the potent antioxidant action of L-Carnosine, the naturally derived nutrient is shown to play a protective role for telomeres while decreasing the rate of telomere shortening during cell division, effectively slowing down the aging process of your cells.

L-Carnosine is found in high concentrations in the muscle and in the brain. It’s believed to possess a significant number of powerful antioxidant properties and has been proposed to be a potential anti-aging compound for aging skin, brain functioning, and conditions of the eyes.

CHLORELLA

Oxidative agents like free radicals can cause damage to your cellular DNA, including telomere length. In one study, cells exposed to the oxidative effects of hydrogen peroxide, telomere length decreased significantly, coupled with a decline of telomerase activity. Telomerase is our enzyme responsible for lengthening telomeres.

However, these decreases were prevented with prior and post treatment of Chlorella vulgaris to those cells. Chlorella, a powerful biochemical detoxifier, has been found to be an effective preventive against telomerase-shortening due to oxidative damage.

GRAPE SEED POLYPHENOLS

Grape Seed Polyphenols contain oligomeric proanthocyanadins, OPCs, a group of powerful bioflavonoids. They have documented effectiveness as free radical scavengers. There is evidence that OPC’s may play a role in inhibiting enzymes that are involved in the degrading of skin and blood vessels.

MAGNESIUM

Magnesium is necessary for many enzymes involved with your DNA replication and repair. Dietary magnesium has also been shown to positively correlate with increased telomere length in women.

One animal study shows that magnesium deficiency is associated with increased free radical damage and shorter telomeres. A human cell study shows that magnesium deprivation causes rapid loss of telomeres and inhibits cell replication, the most important genetic role of telomeres.

It appears the lack of magnesium ions has a negative influence on genome integrity. Insufficient amounts of magnesium also reduce your body’s ability to repair damaged DNA, and can induce chromosomal abnormalities.

According to the authors of a recent study, they stated, “it’s reasonable to hypothesize that magnesium influences telomere length by affecting DNA integrity and repair, in addition to its potential role in oxidative stress and inflammation.”

Magnesium deficiency is common in the United States and likely contributes to rapid aging. Ensuring magnesium adequacy supports many aspects of your health, including the length of telomeres.

OVERALL HEALTH BENEFITS

It’s important to note, that you’re getting many additional health benefits from all these powerful nutritional ingredients to support your heart, brain, liver, and other key organs and systems. TeloVite is a game changer, because taken as an entire formula, it provides two tiers of benefits:

TeloVite ingredients empower your energy, immunity, vitality, skin quality, and a general feeling of well-being – right now. That in itself is great, but you get long term longevity support, because over your life time, these ingredients are strengthening and lengthening your telomeres – those parts of your cells’ DNA responsible for lifespan.

With the introduction of TeloVite, we have entered a new era of dietary supplementation, Nutrigenomics*.

Welcome to the future, and welcome aboard.

*Nutrigenomics is a branch of nutritional genomics and is the study of the effects of foods and food constituents on gene expression. This means that nutrigenomics is research focusing on identifying and understanding molecular-level interaction between nutrients and other dietary bioactives with the genome.