Directed application team in the development of a small, handheld gas chromatograph - differential mobility detector (GC-DMS) for use in chemical warfare agent detection, toxic industrial chemical analyses, and detection and identification of biological species.

Directed and participated in sensor chip system improvements in expanding the number of explosive compounds that could be detected in the Thermo Electron Corporation Egis™ Defender.

ESA Inc., Chelmsford, MA, Director of Development, 1991 - 2004

Manager Sensor Development, 1989 - 1991Scientist, 1988 - 1989

As the Director of the Engineering Division for analytical instrument company, responsible for research and development for new and existing products in analytical instrumentation, including electrochemical (EC) detectors for high performance liquid chromatography (HPLC) and medical device blood lead detectors.

Led the team that developed a research and development 100 award-winning charged aerosol detector (Corona® CAD™), which is a unique, universal detector technology for HPLC.

Managed chemistry/engineering team of 12 that developed an HPLC-EC detector for half of the production costs and one quarter the size of previous model while significantly improving sensitivity. Detector development was on budget, on schedule, and met target costs.

Directed the detector software development and regulatory compliance with 21 CFR part 11. Resulted in increased product sales of more than 100%.

Principal investigator and project manager, Centers for Disease Control and Prevention (CDC) contract:

Developed CLIA "waived" point-of-care blood lead analyzer (joint research and development venture). Project resulted in a marketed portable, hand-held blood lead analyzer using disposable electrodes for physician offices.

Product gained company $10 million in new business (growth of 20%) in an overall declining blood lead testing market place.

Managed research and development team that developed novel biosensor for immunoassay resulting in new product line at this Johnson & Johnson subsidiary.

Research and development on disposable sensors for the ChemPro 1000 point of care chemistry analyzer including ISEs (ion-selective electrodes).

Saved millions of dollars in biosensor production costs by eliminating waste through the development and application of a new spraying system for precisely applying a biological reagent during sensor production.

Research and development on biosensors and DNA probes using amperometry, potentiometry, and electrogenerated chemiluminescence.

Conceived, supervised, and performed experiments leading to the site-specific attachment of an enzyme-cofactor to electrode surfaces, resulting in the issuing of patents and publications vital to the future development of a generic biosensor.