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Hun, Benadryl is why your legs are going nuts. It doesnt like our RLS apparently. It has an ingredient that reacts against the RLS.

Sorry about the Vicodin, i have said before we dont have it in the UK, so dont understand the ins and outs of that med. apart from being a very strong pain killer.

You should look at all the no no meds for RLS, and make a note of them, so in any emergency situation you wont be given something which will send your legs over the top. wwwrlshelp.org has a download of meds which you can print out and keep with you.

Elisse is right. Never let anyone give you benedryl / Diphenhydramine. It will make your legs bonkers. We talk about diphenhydramine all the time. They can give you something else for hives, besides that med. I am sorry it happened, but that should be on a card in your wallet on a "no-no" list. rlshelp.org