Ranaudo will be looking to help bolster a depleted Boston rotation that lost four of its five season-opening starters over the past five days.

Taken by the Red Sox with the 39thpick of the 2010 draft after a stellar career at LSU, Ranaudo has overcome a series of setbacks and injuries on his way to posting one of the strongest seasons of his career in 2014.

Ranaudo has been on the top pitchers in the International League this season with Triple-A Pawtucket, leading the league in wins (12) while ranking second in ERA (2.41) and third in WHIP (1.15).

Ranaudo is in the midst of one of the strongest stretches of his career, as the 6-foot-7 righty has compiled an ERA of 1.94 since June, striking out 46 and walking 17.

Capuano will be looking to get his first win as a starter this season against the team that he opened the year with, as the southpaw posted a 1-1 record with a 4.55 ERA out the Red Sox bullpen before being designated for assignment June 25.

“It was a tough last month [with Boston], but really it was a tough last week. I grew up in New England, I grew up in Springfield, Mass., where it’s pretty much a 50-50 Yankees-Red Sox split,” Capuano said. “To have the opportunity to play for both teams in one year I think is unique and pretty special, and more than anything, I’m just excited to be back in the big leagues and starting.”

After being released by the Red Sox on July 1, Capuano signed a minor league deal with the Rockies before eventually getting traded to the Yankees on July 24.

Capuano was solid in his first start with the Yankees on Saturday against the Blue Jays, surrendering just five hits and two earned runs in what was eventually a 6-4 Toronto victory.

“Good job. He did a really good job, gave us six good innings,” Yankees manager Joe Girardisaid after the game. “I said we’d use him around 100 pitches and that’s what he gave us and he did a nice job.”

Capuano has only faced off against the Red Sox once in his career, allowing two earned runs over six innings as a member of the Dodgers on Aug. 25.