From BWI Airport

Take Route 295 North (Baltimore/Washington Parkway) towards Baltimore. In Baltimore, continue on 295 past the M&T Bank and Oriole Park at Camden Yards stadiums to Pratt Street. Turn right onto Pratt Street and continue east to Calvert Street. Turn left on Calvert Street and proceed north approximately 3 1/2 miles to University Parkway. Turn left on University Parkway and proceed approximately 1/3 mile (past JHU stadium and down hill) to San Martin Drive. Turn left at the signal and proceed approximately 1/4 mile to STScI.

From Points North (Pennsylvania-Philadelphia-New York)

Take Interstate 95 (I-95) or Interstate 83 (I-83) south to Interstate 695 West. Proceed on I-695 west to Exit 23 (I-83 South/Jones Fall Expressway). Take I-83 south to Exit 9A (Coldspring Lane). Left onto Coldspring Lane and proceed approximately 1 mile to Roland Avenue (top of hill). Turn right at signal and proceed approximately 100 yards to signal. Bear left at signal/road split, then continue down road (now University Parkway) approximately 1 mile to San Martin Drive. Turn right at the signal and proceed approximately 1/4 mile to STScI.

From Points South (Washington DC-Dulles-Northern Virginia)

Take Interstate 95 (I-95) north to I-395 (Downtown Baltimore). Proceed on I-395 north (bearing left at road split) to Pratt Street. Turn right onto Pratt Street and continue east to Calvert Street. Turn left on Calvert Street and proceed north approximately 3 1/2 miles to University Parkway. Turn left on University Parkway and proceed approximately 1/3 mile (past JHU stadium and down hill) to San Martin Drive. Turn left at the signal and proceed approximately 1/4 mile to STScI.