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Hmmmm that is interesting. But this would only apply to breeders who were DNA testing their breeding dogs? Do I just misunderstand this piece when I come to the conclusion that yes you should breed the carriers to expand the gene pool and even tho less dog would be affected by using the carrier it still could happen however this is the best way to try and keep the carriers good genes in???? Don't worry I'm not going to breed cavaliers or any other animals for that matter I'm just still trying to understand it all.

Hmmmm that is interesting. But this would only apply to breeders who were DNA testing their breeding dogs?

Correct. The breeder has to know whether or not the dog is a carrier. Carriers are asymptomatic of the disorder, so you cannot tell just by looking.

Originally Posted by MomObvious

... Do I just misunderstand this piece when I come to the conclusion that yes you should breed the carriers to expand the gene pool and even tho less dog would be affected by using the carrier it still could happen however this is the best way to try and keep the carriers good genes in????

I am not sure I am following you here. If a carrier is bred with a clear mate, then half of the offspring should be carriers and the other half should be clear. None of the offspring should be affected. As long as a carrier is mated with a clear dog, none of the offspring should be affected.

Once the first litter is produced, those offspring can be tested to determine which are clear and which are carriers. The breeder then can breed away from the carriers in her bloodline by breeding only the clear offspring in the next generation.

Correct. The breeder has to know whether or not the dog is a carrier. Carriers are asymptomatic of the disorder, so you cannot tell just by looking.

I am not sure I am following you here. If a carrier is bred with a clear mate, then half of the offspring should be carriers and the other half should be clear. None of the offspring should be affected. As long as a carrier is mated with a clear dog, none of the offspring should be affected.

Once the first litter is produced, those offspring can be tested to determine which are clear and which are carriers. The breeder then can breed away from the carriers in her bloodline by breeding only the clear offspring in the next generation.