This research
characterized and optimized a GnRH-based spawning induction
technology for striped bass and related species, using
sustained-release biodegradable GnRHa delivery systems.
The recipient demonstrated that D-Arg6
-cGnRHII (an analog of a common perciform GnRH) is equally
important compared to the D-Ala6
-mGnRH agonist (which is currently used in culture situations).
Doses for acute administration and analog effectiveness
in eliciting in vivo gonadotropin release also
were established. Finally, the data demonstrated rapid
and satisfactory clearance rates of the GnRHa from fish
tissues. This research was conducted in view of facilitating
regulatory approval of the GnRH-based technology and its
large-scale application in the aquaculture industry.