Although treatment options exist, patients with pulmonary arterial hypertension have a poor prognosis. Current recommendations include combination therapies that target the endothelin, nitric oxide, and prostacyclin pathways. The burden and risks of the administration of intravenous prostacyclin therapy likely contribute to the many patients who die before receiving this treatment.

Approximately 29.1 million Americans have diabetes, and at least 86 million Americans aged >20 years have prediabetes. Type 2 diabetes was once more common in people aged >45 years, but is now appearing more in young people and children. Although many factors can increase your risk for diabetes, disease onset can be delayed or even prevented. The following tips may help to lower your risk for diabetes.