A potential association was found for exposure to ambient air concentrations of suspected neurotoxicant hazardous air pollutants, specifically aromatic solvents, among place of residence in 2002 and 1999 and risk of Amyotrophic Lateral Sclerosis.

Some air toxics were associated with autism spectrum disorder risk and severity, including some traffic-related air pollutants and newly-reported associations, but other previously reported associations with metals and volatile organic compounds were not reproducible.

Children with autism/autism spectrum disorder and developmental delay were similar to typically developing controls for all polybrominated diphenyl ether congeners, but levels were high for all three groups.

Multiple chemical contaminants were quantified in the plasma of pregnant women; PFOA had the highest detection rate in cord plasma; however, compared to other Canadian and international studies, our participants had lower contaminant concentrations of these substances.

The objective of this paper is to use statistical methods to compare the concentrations of select persistent organic pollutants and metals in the blood of primiparous women from Canada and Mexico after adjusting for covariates.

Within a mixture of 24 toxicants measured in breast milk, p,p'-DDT was the single toxicant associated with behavioral problems at 12 months using different methods for handling numerous correlated exposures.

Although remote from pollution sources, the Faroe Islands show high concentrations of persistent organic pollutants in human milk, particularly polychlorinated biphenyls, but also polybrominated diphenyl ethers.

An overall higher endocrine-disrupting chemical contamination in the follicular micro-environment was associated with a decreased fertilization rate and consequently with a lower chance of an oocyte to develop into a high-quality embryo.

Health Outcomes and Measures of the Environment (HOME) | National Health and Nutrition Examination Survey (NHANES)

We used a semi-Bayesian hierarchical regression model to estimate associations between prenatal blood or urine concentrations of 52 suspected endocrine disrupting chemicals and autistic behaviors at 4 and 5 years of age in a prospective birth cohort of 175 mothers and their children.

In summary, the correlation analysis presented here of multiple environmental exposures among pregnant women provide a first picture of the structure of the exposome during the crucial in utero period.

This study aimed to identify electronic products that contributed to halogenated flame retardants (HFRs) measured in indoor dust and to develop a screening method for identifying HFRs in hard polymer products.

Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS)

Our findings confirm that exposure to the penta-brominated diphenyl ethers mixture is ongoing, and that Mexican-American children living in California may be experiencing higher polybrominated diphenyl ether exposure from their environment compared to children sampled from the general U.S. population.

Exposure to several polyhalogenated compounds was associated with modifications of the thyroid parameters in adult Inuit, mainly by reducing total triiodothyronine and thyroxine-binding globulin circulating concentrations.

The aim of the present inventory was to determine the levels of PBDEs (n = 6), 2,2',4,4',5,5'-hexabromobiphenyl (BB-153), and 2,2',4,4',5,5'-hexachlorobiphenyl (CB-153) in archived serum samples collected over 1985-2002 in order to assess the concentration change over time in serum for the target analytes.

Pooling of surplus serum from individual samples, collected between 2007 and 2009 during Cycle 1 of the Canadian Health Measures Survey (CHMS), was performed to develop a national baseline estimate of brominated flame retardants in Canadians.

Our objective was to characterize predictors of exposure to polybrominated diphenyl ethers among a multi-ethnic, low-income cohort of pregnant women enrolled from highly urban communities in New York City between years 2009-2010.

Our results suggested that maternal PBDE47 exposure altered CpG site specific DNA methylation at the TNF-alpha promoter, which may contribute to the aberrant TNF-alpha gene expression in the offspring.

The objectives of the present study were: (1) to indentify and quantify the methoxylated/hydroxylated brominated diphenyl ethers and bromophenols in blood plasma of people living in Hong Kong; (2) to assess potential sources and bioaccumulation of these compounds in humans; and (3) to evaluate the contribution of dietary intakes of these compounds via consumption of fish.

In this investigation of polybrominated diphenyl ether (PBDE) body burdens in repeated serum samples from a cohort of Great Lakes residents, we noted increasing geometric mean levels of PBDE and BDE congeners between 1994-1995 and 2001-2003 and 1994-1995 and 2004-2005, but not from 2001-2003 to 2004-2005.

To investigate relationships between the home environment and internal exposure, we assessed associations between two organophosphate flame retardants, tris(1,3-dichloropropyl) phosphate and triphenyl phosphate, in paired hand wipe and dust samples and concentrations of their metabolites in urine samples.

The aim of this study was to conduct an integrated assessment of polybrominated diphenyl ethers exposure and human body burden using 10 matched samples of human milk, indoor air and dust collected in 2007-2008 in Brisbane, Australia.

We present concentrations and partitioning ratios of polybrominated diphenyl ethers (PBDE) in milk and serum from women; modeled predictions of milk PBDE concentrations using serum concentrations appear to be a valid method for estimating PBDE exposure in U.S. infants.