SYSTEM AND METHOD FOR TRAINING AND PROMOTING A CONDITIONED REFLEX INTERVENTION DURING SLEEP - An apparatus and method for causing a conditioned reflex in a person. The apparatus includes a detector configured to detect a physiological condition of the person, the physiological condition associated with an onset of a sleep apnea event. The apparatus also includes a controller configured to transmit a stimulus to the person upon a detection of the physiological condition. The controller is also configured to determine if the physiological condition is still occurring. The controller is further configured, upon a determination that the physiological condition is still occurring, to repeat the transmitting and determining steps.

2011-03-17

20110065981

Methods and Compositions for Improved Fertilization and Embryonic Survival - Single nucleotide polymorphic sites at positions 19069 and 25402 of the bovine STAT3 gene are associated with improved fertilization rate and/or improved embryo survival rate. The interactions between these two polymorphisms, and between them and the bovine STAT1 gene and fertilization and early embryonic survival rates were also disclosed. The interactions between STAT3 SNPs, and between STAT1 and STAT3 SNP19069 were highly significant for embryonic survival rate. Also disclosed are nucleic acid molecules, kits, methods of genotyping and marker assisted bovine breeding methods.

2011-03-17

20110065982

SYSTEM AND METHOD FOR DETERMINING AIRWAY DIAMETER USING ENDOSCOPE - A method and system for use with an endoscopic instrument determines anatomical properties of body lumen at various states. Lumen properties such as lumen diameter are identified in two or more states corresponding to, for example, an inflated or deflated state. The lumen states are registered with one another and the anatomical properties are identified in real time at the location of an endoscope or endoscopic instrument used with the endoscope. In one embodiment a diametrical range of an airway is identified in real time at the location of a bronchoscope.

2011-03-17

20110065983

Ingestible Circuitry - The present invention provides for safe and reliable electronic circuitry that can be employed in ingestible compositions. The ingestible circuitry of the invention includes a solid support; a conductive element; and an electronic component. Each of the support, conductive element and electronic component are fabricated from an ingestible material. The ingestible circuitry finds use in a variety of different applications, including as components of ingestible identifiers, such as may be found in ingestible event markers, e.g., pharma-informatics enabled pharmaceutical compositions.

2011-03-17

20110065984

COMBINATION ENDOSCOPIC OPERATIVE DELIVERY SYSTEM - An endoscope for performing minimally invasive surgery includes along a portion of its length a means such as a groove for slidingly engaging with a corresponding means such as a tongue in a second endoscope and guiding the second endoscope into the patient. Multiple endoscope may be connected together and guide one another into or out of a patient. The tongue structure may include incongruous portions to permit two endoscopes to be partially connected and guided by one another.

2011-03-17

20110065985

ENDOSCOPIC INSTRUMENT - An endoscopic instrument has a proximally arranged operating part, a distally arranged instrument head and a shaft connecting the operating part to the instrument head. A number of instrument channels guided through the shaft open out on the instrument head. These instrument channels run obliquely outwardly in the distal direction with respect to a central axis of the instrument head in a section of the channels that adjoins the distal openings thereof.

2011-03-17

20110065986

POSITIONING SYSTEM FOR MANIPULATING A CHANNEL WITHIN A MEDICAL DEVICE - Embodiments of the invention include a medical device for accessing a patient's body portion and used for diagnosis and treatment of medical conditions. Embodiments of the invention may include a particular endoscopic positioning mechanism for placing an endoscope and an additional treatment device within desired body portions in order to assist in diagnosis and treatment of anatomical diseases and disorders. In particular, a medical device according to an embodiment of the invention includes a positioning mechanism configured for movement through at least two degrees of freedom.

2011-03-17

20110065987

MINIATURE INGESTIBLE CAPSULE - A miniature ingestible capsule has multiple therapeutic or diagnostic operations that can be performed. These functions are controlled by a combination of an outside control, a pose beacon and through information relayed from an imagining array and transmitter. These functions can be in a separate capsule without an imaging array or within the same capsule with an imaging array. Typically, there is one function performed in addition to imaging. These functions can include suction and spray capabilities, ultrasound sensor, lithotripsy, laser, heat, electrocautery, BICAP, biopsy forceps, a needle knife snare cautery (cold and hot with continuous or pulsed current for cutting and coagulation), with a basket, and fine needle aspiration with various wheels and fins and motors controlled externally and other tools to be used in humans. All of these tools can be attached to a retractable arm. Also, they can be used on an elevator device that lifts them, allowing for an extra 180° of movement.

2011-03-17

20110065988

PROPELLABLE APPARATUS WITH ACTIVE SIZE CHANGING ABILITY - A propellable apparatus comprises one or more rotatable membranes. The rotatable membranes include an inner surface at least partially defining an encircled region and a continuous outer surface that turns outward to engage a cavity or lumen wall, for example, and turns inward to at least partially encompass a central region defining a longitudinal path. The membranes are powerable to provide movement relative to the cavity or lumen wall. The apparatus further comprises an inflatable and deflatable support structure, configured to bias the outer surface of the membranes outward to engage the cavity or lumen wall at a first outer diameter, and be deformable inward in response to a compressive force or operator command to provide a second outer diameter that is less than the first outer diameter. In some examples, the rotatable membranes include belt-like membranes, and the inflatable and deflatable support structure includes at least one impermeable bladder.

2011-03-17

20110065989

SYSTEM FOR ASSESSMENT OF COLONOSCOPE MANIPULATION - A comprehensive system for objective assessment of colonoscope manipulation includes a handgrip for collecting and transmitting colonoscope handling data including force and motion data; a patient pain monitor for collecting and transmitting data on the level of patient's pain and discomfort; and digital processing means for extracting useful features such as colonoscope tip advancement speed from colonoscope-provided video images. All data is wirelessly transmitted to an electronic unit for processing and displaying on a monitor. A colonoscopy procedure is properly conducted when certain shaft advancement causes appropriate tip advancement, all without an increased level of patient's pain. The system of the invention is aimed at providing objective assessment data allowing for safer and less painful colonoscopies.

HANDGRIP FOR ASSESSMENT OF COLONOSCOPE MANIPULATION - A handgrip for colonoscope shaft is equipped with force, torque, and acceleration sensors allowing for a comprehensive characterization of colonoscope shaft motion, including recognition of obstacles and recording of forces and torques applied at various times during a colonoscopy procedure. An electronic unit is adapted to receive sensors data wirelessly and calculate a variety of motion parameters guiding a medical practitioner during the procedure and aimed at making colonoscopy safer and less painful.

STEERABLE SEGMENTED ENDOSCOPE AND METHOD OF INSERTION - A steerable endoscope has an elongated body with a selectively steerable distal portion and an automatically controlled proximal portion. The endoscope body is inserted into a patient and the selectively steerable distal portion is used to select a desired path within the patient's body. When the endoscope body is advanced, an electronic motion controller operates the automatically controlled proximal portion to assume the selected curve of the selectively steerable distal portion. Another desired path is selected with the selectively steerable distal portion and the endoscope body is advanced again. As the endoscope body is further advanced, the selected curves propagate proximally along the endoscope body, and when the endoscope body is withdrawn proximally, the selected curves propagate distally along the endoscope body. This creates a serpentine motion in the endoscope body allowing it to negotiate tortuous curves along a desired path through or around and between organs within the body.

2011-03-17

20110065994

ENDOSCOPE - The endoscope is equipped with: a curving manipulation unit provided on the main body manipulating unit, for performing a manual operation which causes the curving portion; a curving drive unit for coupling the curving manipulation unit to the curving portion so as to curve the curving portion in response to a manipulation performed by the curving manipulation unit; a manipulating force detecting unit for detecting a manipulating force applied to the curving manipulation unit; a manipulation assisting power calculating unit for calculating manipulation assisting power corresponding to the manipulating force detected by the manipulating force detecting unit; and a rotation driving force generating unit for applying a driving force via a driving force transferring mechanism to the curving drive unit, so as to generate the manipulation assisting power calculated by the manipulation assisting power calculating unit; in which the rotation driving force generating unit is arranged in an appendix unit.

2011-03-17

20110065995

IN-LINE GAS ADAPTOR FOR ENDOSCOPIC APPARATUS - The present invention provides an adaptor that is suitable for attachment to an endoscopic device for delivery of a secondary gas. The adaptor can comprise a substantially cylindrical body with a two, opposing closed ends, two fluid transport channels extending through the cylindrical body and opening at the closed ends, and an inlet port extending outward from the cylindrical body and being in fluid connection with one of the fluid transport channels. The adaptor may be used in endoscopy methods and is particularly useful for adding a secondary gas source in an endoscopy procedure.

2011-03-17

20110065996

CASSETTE FOR IRRIGATION OR ASPIRATION MACHINE FOR ENDOSCOPY - A cassette insertable into an irrigation or aspiration machine for endoscopy includes an irrigation or an aspiration tube and a support provided with one or two inlet plugs and one or two outlet plugs where two tubes form an elbow to be connectable to the inlet or outlet plugs in an input and output direction of motion, respectively and to form an irrigation or aspiration pumping area in the input and output direction of motion. The support includes a T-shaped guide according to the head of the T for protecting the elbow of each tube and according to the length of the T body in a slot guiding the tube in the output direction. The T-shaped guide extends between one or two inlet plugs to form the irrigation or aspiration pumping area on both sides of the slot between each inlet plug and the head of the T.

2011-03-17

20110065997

REMOVABLE SUCTION ASSEMBLY FOR MEDICAL HANDPIECES - Systems and methods provide for more efficient cleaning and sterilizing of surgical handpieces by using a removable valve assembly. The valve assembly is removable to provide access to a first suction passageway and a second suction passageway for cleaning purposes. The first suction passageway may also be removable.

2011-03-17

20110065998

ENDOSCOPIC FLUID CONTROL APPARATUS - An endoscopic fluid control apparatus includes a cylinder which is attachable to an attachment part attached to an endoscope, and includes a first channel which transfers fluid to an insertion channel of the endoscope, a piston which is set on the cylinder and includes a valve part movable relative to the cylinder between a position where the first channel is opened relative to the insertion channel and a position where the first channel is closed relative to the insertion channel, a connection port part for connecting a fluid tube, and a second channel which transfers the fluid from the connection port part to the insertion channel, an elastic member which holds the piston to be movable relative to the cylinder between the position where the first channel is closed and the position where the first channel is opened, a first engagement part which engages the piston and the elastic member with each other so as not to rotate about an axis of movement of the piston, and a second engagement part which engages the cylinder and the elastic member with each other so as not to rotate about an axis of movement of the cylinder.

SCOPE AND MAGNETIC INTRODUCER SYSTEMS AND METHODS - Exemplary scope systems and methods involve a cannula assembly, a sheath assembly, and a tubing set. A cannula assembly, which may be a non-magnetic scope cap assembly, can include a cannula body, a proximal housing having a strap, an optical window, and a luer for suction or flushing. A cannula body may include a first lumen or scope channel for receiving a visualization device such as an endoscope or laparoscope, a distal end having suction or flushing flush apertures, and a second lumen for providing fluid communication between the apertures and the luer. Exemplary magnetic introducer systems and methods involve a cannula assembly, a sheath assembly, a tubing set. In some cases, the cannula assembly of a magnetic introducer system can be a magnetic scope cap assembly. In addition to cannula and sheath assemblies, magnetic introducer systems can include a magnetic introducer tubing assembly and a stylet assembly.

2011-03-17

20110066001

Access Method With Insert - Various devices and methods are provided with respect to inserting multiple surgical instruments through a single surgical access device. A medical device including a flexible tissue retractor and a releasable insert having multiple instrument openings is disclosed. The insert can be in the form of an insert assembly including multiple components. A method of using the insert is also described, and includes releasably positioning an insert having multiple instrument openings into the tissue retractor

2011-03-17

20110066002

PANDEMIC DIAGNOSTIC AND INTERVENTION TOOL FOR EMERGENCY DISPATCH - A system and method to assist an emergency medical dispatcher in responding to emergency calls. A computer implemented emergency medical dispatch protocol includes interrogatories for a dispatcher to ask a caller to generate an appropriate response. A diagnostic tool is provided to aid the dispatcher in gathering symptom information for a patient who may be suffering from a pandemic illness, such as a severe respiratory infection like influenza. The diagnostic tool facilitates uniform and consistent gathering of symptom information relating to a pandemic outbreak. The information may be stored and/or processed for use in monitoring and/or tracking pandemic outbreaks. The diagnostic tool can be launched automatically by the emergency dispatch protocol, or manually by a dispatcher. The diagnostic tool presents a user interface that provides, among other things, instructions, symptoms, and input fields.

PASSIVE PHYSIOLOGICAL MONITORING (P2M) SYSTEM - Passive physiological monitoring apparatus and method has a sensor for sensing physiological phenomenon. A converter converts sensed data into electrical signals and a computer receives and computes the signals and outputs computed data for real-time interactive display. The sensor is a piezoelectric film of polyvinylidene fluoride. A band-pass filter filters out noise and isolates the signals to reflect data from the body. A pre-amplifier amplifies signals. Signals detected include mechanical, thermal and acoustic signatures reflecting cardiac output, cardiac function, internal bleeding, respiratory, pulse, apnea, and temperature. A pad may incorporate the PVDF film and may be fluid-filled. The film converts mechanical energy into analog voltage signals. Analog signals are fed through the band-pass filter and the amplifier. A converter converts the analog signals to digital signals. A Fourier transform routine is used to transform into the frequency domain. A microcomputer is used for recording, analyzing and displaying data for on-line assessment and for providing realtime response. A radio-frequency filter may be connected to a cable and the film for transferring signals from the film through the cable. The sensor may be an array provided in a MEDEVAC litter or other device for measuring acoustic and hydraulic signals from the body of a patient for field monitoring, hospital monitoring, transport monitoring, home, remote monitoring.

2011-03-17

20110066005

MUTLI PURPOSE CRITERIA BASED ADAPTIVE TRAINING SYSTEM - A system and method include a computer implemented training framework that adapts its behavior to different types of training goals. The system utilizes a measured neuro-physiological state of a student to provide at least one of self regulation feedback and training environment feedback to optimize a learning experience for one or more different types of scenarios.

2011-03-17

20110066006

SYSTEM FOR MEASURING VITAL SIGNS DURING HEMODIALYSIS - The invention provides a system for continuously monitoring a patient during hemodialysis. The system includes a hemodialysis machine for performing the hemodialysis process that features a controller, a pump, a dialyzer filter, a lumen, and an interface to a body-worn monitor. A patient attaches to the dialysis machine through the lumen, and wears a body-worn monitor for continuously measuring blood pressure. The monitor includes an optical system for measuring an optical waveform, an electrical system for measuring an electrical waveform, and a processing component for determining a transit time between the optical and electrical waveforms and then calculating a blood pressure value from the transit time. The body-worn monitor features an interface (e.g. a wired serial interface, or a wireless interface) to transmit the blood pressure value to the controller within the hemodialysis machine. The controller is configured to receive the blood pressure value, analyze it, and in response adjust the dialysis process.

2011-03-17

20110066007

BODY-WORN MONITOR FOR MEASURING RESPIRATION RATE - The invention provides a multi-sensor system that uses an algorithm based on adaptive filtering to monitor a patient's respiratory rate. The system features a first sensor selected from the following group: i) an impedance pneumography sensor featuring at least two electrodes and a processing circuit configured to measure an impedance pneumography signal; ii) an ECG sensor featuring at least two electrodes and an ECG processing circuit configured to measure an ECG signal; and iii) a PPG sensor featuring a light source, photodetector, and PPG processing circuit configured to measure a PPG signal. Each of these sensors measures a time-dependent signal which is sensitive to respiratory rate and, during operation, is processed to determine an initial respiratory rate value. An adaptive digital filter is determined from the initial respiratory rate. The system features a second sensor (e.g. a digital 3-axis accelerometer) that attaches to the patient's torso and measures an ACC signal indicating movement of the chest or abdomen that is also sensitive to respiratory rate. This second signal is processed with the adaptive filter to determine a final value for respiratory rate.

2011-03-17

20110066008

BODY-WORN MONITOR FOR MEASURING RESPIRATION RATE - The invention provides a multi-sensor system that uses an algorithm based on adaptive filtering to monitor a patient's respiratory rate. The system features a first sensor selected from the following group: i) an impedance pneumography sensor featuring at least two electrodes and a processing circuit configured to measure an impedance pneumography signal; ii) an ECG sensor featuring at least two electrodes and an ECG processing circuit configured to measure an ECG signal; and iii) a PPG sensor featuring a light source, photodetector, and PPG processing circuit configured to measure a PPG signal. Each of these sensors measures a time-dependent signal which is sensitive to respiratory rate and, during operation, is processed to determine an initial respiratory rate value. An adaptive digital filter is determined from the initial respiratory rate. The system features a second sensor (e.g. a digital 3-axis accelerometer) that attaches to the patient's torso and measures an ACC signal indicating movement of the chest or abdomen that is also sensitive to respiratory rate. This second signal is processed with the adaptive filter to determine a final value for respiratory rate.

2011-03-17

20110066009

BODY-WORN VITAL SIGN MONITOR - The invention provides a body-worn monitor featuring a processing system that receives a digital data stream from an ECG system. A cable houses the ECG system at one terminal end, and plugs into the processing system, which is worn on the patient's wrist like a conventional wristwatch. The ECG system features: i) a connecting portion connected to multiple electrodes worn by the patient; ii) a differential amplifier that receives electrical signals from each electrode and process them to generate an analog ECG waveform; iii) an analog-to-digital converter that converts the analog ECG waveform into a digital ECG waveform; and iv) a transceiver that transmits a digital data stream representing the digital ECG waveform (or information calculated from the waveform) through the cable and to the processing system. Different ECG systems, typically featuring three, five, or twelve electrodes, can be interchanged with one another.

2011-03-17

20110066010

BODY-WORN VITAL SIGN MONITOR - The invention provides a body-worn monitor featuring a processing system that receives a digital data stream from an ECG system. A cable houses the ECG system at one terminal end, and plugs into the processing system, which is worn on the patient's wrist like a conventional wristwatch. The ECG system features: i) a connecting portion connected to multiple electrodes worn by the patient; ii) a differential amplifier that receives electrical signals from each electrode and process them to generate an analog ECG waveform; iii) an analog-to-digital converter that converts the analog ECG waveform into a digital ECG waveform; and iv) a transceiver that transmits a digital data stream representing the digital ECG waveform (or information calculated from the waveform) through the cable and to the processing system. Different ECG systems, typically featuring three, five, or twelve electrodes, can be interchanged with one another.

2011-03-17

20110066011

Method and apparatus for recording and presentation of physiological data - The invention relates to a method and device for recording and presentation of physiological parameters, which can include both blood pressure and heart pulse. Information about the heart pulse is derived from a recorded blood pressure signal, whereby the need for e.g. an external ECG measurement device is eliminated. It is likewise a part of the invention that a blood pressure measurement is used for the derivation of data such as Heart Rate Variability (HRV) and/or baroreflex sensitivity (BRS) values.

2011-03-17

20110066012

NEEDLE INSERTION SYSTEMS AND METHODS - A housing may have a needle, plunger, and bias mechanism supported within the housing by a tab configured to retain the plunger in position and to allow the plunger to move under bias force imparted by the bias mechanism to move the needle to an insert position when the tab is removed. A base and a structure may be configured for relative movement there between and may be adapted to be secured to a user with a cannula extending through a body of the structure into the user during use of a medical device. A housing may be adapted to be secured to a user to support a medical device operable with an insertion needle, the housing having a magnifying material for increasing visibility of an injection site.

2011-03-17

20110066013

PHYSIOLOGICAL PARAMETER MONITORING APPARATUS - A tissue oximeter sensor includes a substrate with a non-zero finite depth and first and second major sides. At least a first material free region extends along the depth from one of the sides to the other of the two sides forming a first well in the substrate. One of the sides of the substrate is configured to be removeably affixed to a human or animal subject. The sensor also includes a first channel with first and second end portions. One of the end portions of the first channel is selectively positioned in the first well along the depth alternatively at one of a plurality of different depth positions. The first channel routes radiation at least one of from the first end portion to the second end portion or from the second end portion to the first end portion.

2011-03-17

20110066014

METHOD AND APPARATUS FOR CEREBRAL OXIMETRY - The present invention pertains to a method and apparatus for cerebral oximetry. A modulated optical signal based on a digital code sequence is transmitted to the human brain. A temporal transfer characteristic is derived from the modulated optical signal. Oxygen level in the brain is determined based on the temporal transfer characteristic.

2011-03-17

20110066015

OXIMETER SENSOR WITH DIGITAL MEMORY ENCODING PATIENT DATA - The present invention provides a memory chip for use in an oximeter sensor, or an associated adapter or connector circuit. The memory chip allows the storing of patient related data, such as patient trending data or a patient ID, to provide enhanced capabilities for the oximeter sensor. In addition to providing unique data to store in such a memory, the present invention include unique uses of the data stored in such a memory.

2011-03-17

20110066016

OPAQUE, ELECTRICALLY NONCONDUCTIVE REGION ON A MEDICAL SENSOR - A medical sensor may be adapted to prevent unwanted light and electrical interference from corrupting physiological measurements. Sensors are provided with features that reduce the amount of outside light or shunted light that impinge the detecting elements of the sensor. The sensor is adapted to reduce crosstalk between electrical signals, increasing the accuracy of measurements. The sensor is also adapted to reduce the effect of outside light or shunted light on pulse oximetry measurements.

2011-03-17

20110066017

METHOD AND APPARATUS FOR POST-SHOCK EVALUATION USING TISSUE OXYGENATION MEASUREMENTS - A method and apparatus for controlling delivery of therapy that includes an emitting portion emitting light at a predetermined emitted light intensity to a volume of tissue at a plurality of wavelengths, and a detecting portion detecting the emitted light scattered by the volume of tissue to generate corresponding detected light intensity output signals. A control module controls the light emission so that an emitted light intensity at each of the plurality of wavelengths is within a predetermined intensity range, and determines a tissue oxygenation index in response to only the detected light intensity output signals, and a therapy delivery module delivers therapy in response to the determined tissue oxygenation index.

2011-03-17

20110066018

METHOD AND APPARATUS FOR POST-SHOCK EVALUATION USING TISSUE OXYGENATION MEASUREMENTS - A method and apparatus for controlling delivery of therapy that includes an emitting portion emitting light at a predetermined emitted light intensity to a volume of tissue at a plurality of wavelengths, and a detecting portion detecting the emitted light scattered by the volume of tissue to generate corresponding detected light intensity output signals. A control module adjusts the detected light intensity output signals for shifts in intensity corresponding to the emitted light intensity, and determines a tissue oxygenation index in response to only the adjusted detected light intensity output signals, and a therapy delivery module controlling therapy in response to the determined tissue oxygenation index.

2011-03-17

20110066019

Biosensor Membranes Composed Of Polymers Containing Heterocyclic Nitrogens - Novel membranes comprising various polymers containing heterocyclic nitrogen groups are described. These membranes are usefully employed in electrochemical sensors, such as amperometric biosensors. More particularly, these membranes effectively regulate a flux of analyte to a measurement electrode in an electrochemical sensor, thereby improving the functioning of the electrochemical sensor over a significant range of analyte concentrations. Electrochemical sensors equipped with such membranes are also described.

2011-03-17

20110066020

MULTI-CHANNEL EEG ELECTRODE SYSTEM - A multi-channel EEG electrode system has a plurality of electrodes operable to sense an EEG signal. The electrodes are arranged in a three-dimensional pattern and each has an identification and includes an indicating unit that displays information at a position at which it is placed. An image sensing device acquires stereoscopic images of the plurality of electrodes. A control device sequentially causes the indicating unit of each electrode to display the information and simultaneously cause the image sensing device to acquire the stereoscopic images of each electrode. A processing device calculates position information of the electrodes from the stereoscopic images and to correlate the position information to the identification of each electrode.

2011-03-17

20110066021

Medical Electrode with Self-Lifting Tabs - A medical electrode includes a backing layer having a top face and a bottom face, and a shrinkable layer covering at least a portion of the top face of the backing layer. Shrinkage of the shrinkable layer results in flexing of a portion of the backing layer to aid placement and attachment of the electrode to the patient.

2011-03-17

20110066022

APPARATUS FOR THE FLEXIBLE POSITIONING OF A RADIATION SOURCE AND A RADIATION DETECTOR - An apparatus for medical examinations includes a first arm that is rotatable about an axis, the first arm being configured to carry a radiation source or a radiation detector. The apparatus for medical examinations also includes a second arm that is rotatable about the axis, the second arm being configured to carry a radiation source or a radiation detector. The second arm is attached to the first arm and is rotatable relative to the first arm.

2011-03-17

20110066023

NON-INVASIVE SUBJECT-INFORMATION IMAGING METHOD AND APPARATUS - A non-invasive subject-information imaging apparatus according to this invention includes a light generating unit which generates light containing a specific wavelength component, a light irradiation unit which radiates the generated light into a subject, a waveguide unit which guides the light from the light generating unit to the irradiation unit, a plurality of two-dimensionally arrayed electroacoustic transducer elements, a transmission/reception unit which transmits ultrasonic waves to the subject by driving the electroacoustic transducer elements, and generates a reception signal from electrical signals converted by electroacoustic transducer elements, and a signal processing unit which generates volume data of a living body function by processing a reception signal corresponding to acoustic waves generated in the subject by light irradiation, and generates volume data of a tissue morphology by processing a reception signal corresponding to echoes generated in the subject upon transmission of the ultrasonic waves.

2011-03-17

20110066024

METHOD AND APPARATUS FOR ACQUIRING AN IMAGE BIOMARKER AND PROGNOSING A BLOOD RELATED DISEASE - A method of acquiring an image biomarker suitable for prognosis of a blood-related disease, such as acute myeloid leukemia, includes the steps of: (a) acquiring physical parameter sets, each including at least two physical parameters, respectively from time-signal intensity curves, the time-signal intensity curves being respectively obtained from magnetic resonance image sets of different subjects that are diagnosed as having the blood-related disease, each of the image sets being acquired through MRI scanning using one of first and second configuration parameter sets; (b) analyzing the physical parameter sets thus acquired with reference to prognoses of the different subjects so as to obtain weight values corresponding to the physical parameters; and (c) establishing a risk score function that is a sum of products of each of the physical parameters and the corresponding weight value, wherein a risk score obtained using the risk score function serves as the image biomarker suitable for prognosis of the blood-related disease.

2011-03-17

20110066025

SYSTEM AND METHOD FOR PHASE OFFSET AND TIME DELAY CORRECTION IN MAGNETIC RESONANCE SPECTROSCOPY DATA - A method is provided for producing, with a magnetic resonance (MR) system, a nuclear magnetic resonance spectrum that has been corrected for errors arising from phase offsets and time shifts in the acquired spectroscopic data. A spectroscopic data set includes temporal information indicative of the underlying phase offsets and time shifts. In general, this temporal information is utilized to correct for errors in the acquired data. As a result, a plurality of acquired spectroscopic data sets are more accurately combined by first individually correcting each spectroscopic data set for such errors. Exemplary sources of the phase offsets and time shifts include the physical separation between a volume of interest and the detectors in the MRI system. Using the temporal information, T

2011-03-17

20110066026

RF COIL FOR USE IN MAGNETIC RESONANCE IMAGING IN INTEGRATED SPECT AND MR IMAGING - An apparatus and method for performing dual modality SPECT/MRI imaging on an object in combination with a whole-body MRI system includes a collimated nuclear radiation detector for receiving radiation from the object, and a radiofrequency MRI coil enveloping the object and interfaced with the collimated nuclear radiation detector. The MRI coil and collimated detector are arranged and configured for disposition within the whole-body MRI system.

2011-03-17

20110066027

Combined Imaging System with a Magnetic Resonance System and a UWB Radar - During operation of a combined imaging system with a magnetic resonance system and a UWB radar, a wireless signal transmission in conjunction with a patient monitoring system is to be enabled in a simpler and more cost-effective manner. To this end, the use of already existing components of the UWB radar is proposed for the wireless signal transmission. This makes it possible to dispense with an additional transmitting and/or receiving antenna for the wireless signal transmission.

2011-03-17

20110066028

SYSTEMS AND METHODS FOR REMOTE MONITORING OF IMPLANTABLE MEDICAL DEVICE LEAD TEMPERATURES DURING AN MRI PROCEDURE - Systems and methods are provided for detecting and responding to excessive heating of implantable medical device leads, such as leads used with pacemakers or implantable cardioverter-defibrillators (ICDs), during a magnetic resonance imaging (MRI) procedure. In one example, a critical temperature is determined for the lead that is representative, e.g., of the temperature at which tissue damage might occur or pacing/sensing might be significantly impaired. A temperature threshold is then set based on the critical temperature by subtracting a predetermined safety margin. Lead temperatures are then sensed during the MRI procedure. The lead temperatures are compared against the threshold and suitable warnings are transmitted to an external monitoring system if lead temperatures exceed their thresholds so that the attending personnel can take corrective action. The implantable device may also be programmed to take corrective action, such as automatically changing pacing modes, adjusting pulse magnitudes or sensitivity values, etc.

2011-03-17

20110066029

Electromagnetic Medical Device - An insertable or implantable medical device includes an elongated member having a proximal end, a distal end, at least one conductive coil near the distal end, and electrical conductors which carry current from the coil towards the proximal end. The coil surrounds or is surrounded by a flexible magnetic polymeric composite.

2011-03-17

20110066030

SYSTEMS AND METHODS FOR SHEAR WAVE FIELD FORMATION - An ultrasound imaging system provides dynamic control of a shear wave front used to image viscoelasticity in a biological tissue. The system receives an indication of a region of interest and selects a shear wave front shape. The system also selects, based on the selected shear wave front shape, focus locations for a plurality of push pulses and a sequence for moving a shear wave source among the focus locations. The system transmits a series of push pulses according to the selected sequence, and determines a speed of the shear wave front as it passes through the region of interest. Changes in the speed of the shear wave front are related to changes in stiffness within the tissue.

2011-03-17

20110066031

ULTRASOUND SYSTEM AND METHOD OF PERFORMING MEASUREMENT ON THREE-DIMENSIONAL ULTRASOUND IMAGE - Embodiments for providing an ultrasound system of performing a 3D measurement, comprise: an ultrasound data acquisition unit configured to transmit ultrasound signals to a target object and receive ultrasound echo signals reflected from the target object to acquire ultrasound data; a user interface configured to receive input data from a user; and a processor configured to form a 3D-ultrasound image based on volume data derived from the ultrasound data, establish two or more points on the 3D-ultrasound image based on the input data, generate connection data among the established two or more points on the 3D-ultrasound image, and measure distances among the established two or more points based on the input data and the connection data.

2011-03-17

20110066032

ASYMMETRIC ULTRASOUND PHASED-ARRAY TRANSDUCER - An asymmetric ultrasound transducer array may include multiple regions or groups of transducer elements. The regions may be configured to generate respective ultrasound beams with different capabilities, such as, e.g., focusing at varying focal depths and lateral steering, and/or focusing into different volumes.

2011-03-17

20110066033

PROBE OF ULTRASONIC DIAGNOSTIC APPARATUS AND METHOD OF SUPPRESSING VIBRATION THEREOF - A probe of an ultrasonic diagnostic apparatus and a method of suppressing vibration thereof are disclosed. The probe includes a transducer moving along a preset locus; a drive unit driving the transducer, a detector sensing real-time vibration of the transducer during movement of the transducer, and a controller controlling operation of the drive unit depending on a sensed degree of vibration to suppress the real-time vibration of the transducer. Factors related to the drive unit and generating vibration of the transducer can be suppressed by changing a drive force transmitted to the transducer depending on a detected degree of real-time vibration of the transducer to suppress vibration of the transducer, thereby improving accuracy in ultrasonic diagnosis and providing a more accurate ultrasound image.

TEMPERATURE PROFILE MAPPING AND GUIDED THERMOTHERAPY - Techniques, apparatus and systems that use an optical probe head to deliver light to a target and to collect light from the target for imaging and monitoring a target while a separate radiation is applied to treat the target.

2011-03-17

20110066036

MOBILE SYSTEM AND METHOD FOR ADDRESSING SYMPTOMS RELATED TO MENTAL HEALTH CONDITIONS - A system and method for addressing mental health conditions includes a mobile processing device capable of executing a software application stored in memory. The software application is configured to employ peripheral devices associated with the mobile processing device to provide a user with a self-treating option for addressing mental conditions. When activated, the application provides one more of an interactive diagnosis routine configured to assist in discovering a mental state or condition of the user, and an interactive instructional routine configured to remedy a current mental state.

2011-03-17

20110066037

BODY-WORN MONITOR FOR MEASURING RESPIRATION RATE - The invention provides a multi-sensor system that uses an algorithm based on adaptive filtering to monitor a patient's respiratory rate. The system features a first sensor selected from the following group: i) an impedance pneumography sensor featuring at least two electrodes and a processing circuit configured to measure an impedance pneumography signal; ii) an ECG sensor featuring at least two electrodes and an ECG processing circuit configured to measure an ECG signal; and iii) a PPG sensor featuring a light source, photodetector, and PPG processing circuit configured to measure a PPG signal. Each of these sensors measures a time-dependent signal which is sensitive to respiratory rate and, during operation, is processed to determine an initial respiratory rate value. An adaptive digital filter is determined from the initial respiratory rate. The system features a second sensor (e.g. a digital 3-axis accelerometer) that attaches to the patient's torso and measures an ACC signal indicating movement of the chest or abdomen that is also sensitive to respiratory rate. This second signal is processed with the adaptive filter to determine a final value for respiratory rate.

2011-03-17

20110066038

BODY-WORN MONITOR FOR MEASURING RESPIRATION RATE - The invention provides a multi-sensor system that uses an algorithm based on adaptive filtering to monitor a patient's respiratory rate. The system features a first sensor selected from the following group: i) an impedance pneumography sensor featuring at least two electrodes and a processing circuit configured to measure an impedance pneumography signal; ii) an ECG sensor featuring at least two electrodes and an ECG processing circuit configured to measure an ECG signal; and iii) a PPG sensor featuring a light source, photodetector, and PPG processing circuit configured to measure a PPG signal. Each of these sensors measures a time-dependent signal which is sensitive to respiratory rate and, during operation, is processed to determine an initial respiratory rate value. An adaptive digital filter is determined from the initial respiratory rate. The system features a second sensor (e.g. a digital 3-axis accelerometer) that attaches to the patient's torso and measures an ACC signal indicating movement of the chest or abdomen that is also sensitive to respiratory rate. This second signal is processed with the adaptive filter to determine a final value for respiratory rate.

2011-03-17

20110066039

BODY-WORN MONITOR FOR MEASURING RESPIRATION RATE - The invention provides a multi-sensor system that uses an algorithm based on adaptive filtering to monitor a patient's respiratory rate. The system features a first sensor selected from the following group: i) an impedance pneumography sensor featuring at least two electrodes and a processing circuit configured to measure an impedance pneumography signal; ii) an ECG sensor featuring at least two electrodes and an ECG processing circuit configured to measure an ECG signal; and iii) a PPG sensor featuring a light source, photodetector, and PPG processing circuit configured to measure a PPG signal. Each of these sensors measures a time-dependent signal which is sensitive to respiratory rate and, during operation, is processed to determine an initial respiratory rate value. An adaptive digital filter is determined from the initial respiratory rate. The system features a second sensor (e.g. a digital 3-axis accelerometer) that attaches to the patient's torso and measures an ACC signal indicating movement of the chest or abdomen that is also sensitive to respiratory rate. This second signal is processed with the adaptive filter to determine a final value for respiratory rate.

2011-03-17

20110066040

PHYSIOLOGIC PARAMETER MONITORING APPARATUS - A physiologic parameter monitor includes a parameter value determiner that determines a parameter value indicative of a response of a human or animal subject to fluid intake during fluid therapy. The parameter value determiner determines the parameter value based on a signal indicative of a non-invasively obtained state of the subject. The physiologic parameter monitor also includes a display that displays the parameter value in a human readable format.

SYSTEM FOR MEASURING VITAL SIGNS DURING HEMODIALYSIS - The invention provides a system for continuously monitoring a patient during hemodialysis. The system includes a hemodialysis machine for performing the hemodialysis process that features a controller, a pump, a dialyzer filter, a lumen, and an interface to a body-worn monitor. A patient attaches to the dialysis machine through the lumen, and wears a body-worn monitor for continuously measuring blood pressure. The monitor includes an optical system for measuring an optical waveform, an electrical system for measuring an electrical waveform, and a processing component for determining a transit time between the optical and electrical waveforms and then calculating a blood pressure value from the transit time. The body-worn monitor features an interface (e.g. a wired serial interface, or a wireless interface) to transmit the blood pressure value to the controller within the hemodialysis machine. The controller is configured to receive the blood pressure value, analyze it, and in response adjust the dialysis process.

2011-03-17

20110066044

BODY-WORN VITAL SIGN MONITOR - The invention provides a body-worn monitor featuring a processing system that receives a digital data stream from an ECG system. A cable houses the ECG system at one terminal end, and plugs into the processing system, which is worn on the patient's wrist like a conventional wristwatch. The ECG system features: i) a connecting portion connected to multiple electrodes worn by the patient; ii) a differential amplifier that receives electrical signals from each electrode and process them to generate an analog ECG waveform; iii) an analog-to-digital converter that converts the analog ECG waveform into a digital ECG waveform; and iv) a transceiver that transmits a digital data stream representing the digital ECG waveform (or information calculated from the waveform) through the cable and to the processing system. Different ECG systems, typically featuring three, five, or twelve electrodes, can be interchanged with one another.

2011-03-17

20110066045

BODY-WORN VITAL SIGN MONITOR - The invention provides a body-worn monitor featuring a processing system that receives a digital data stream from an ECG system. A cable houses the ECG system at one terminal end, and plugs into the processing system, which is worn on the patient's wrist like a conventional wristwatch. The ECG system features: i) a connecting portion connected to multiple electrodes worn by the patient; ii) a differential amplifier that receives electrical signals from each electrode and process them to generate an analog ECG waveform; iii) an analog-to-digital converter that converts the analog ECG waveform into a digital ECG waveform; and iv) a transceiver that transmits a digital data stream representing the digital ECG waveform (or information calculated from the waveform) through the cable and to the processing system. Different ECG systems, typically featuring three, five, or twelve electrodes, can be interchanged with one another.

2011-03-17

20110066046

IMPLANTABLE FLAT BLOOD PRESSURE SENSING CUFF STRUCTURE AND IMPLANTABLE BLOOD PRESSURE MONITORING DEVICE USING THE CUFF STRUCTURE - An implantable flat blood pressure sensing cuff structure and an implantable blood pressure monitoring device use a first portion of the cuff structure that comprises a sidewall that extends from a surface and contains a pressure sensor, and a second portion of the cuff structure that is configured to overlie and be removably relative to the first portion. The first and second portions of the cuff structure are configured to provide an aperture extending transversely through the cuff structure for receiving a blood vessel therein generally sandwiched between the first portion and the second portion when the second portion is positioned on the first portion such that the pressure sensor is operative to detect vessel expansion and contraction.

2011-03-17

20110066047

ECCENTRIC PRESSURE CATHETER WITH GUIDEWIRE COMPATIBILITY - There is herein described a catheter for measuring a pressure in a cardiovascular system. The catheter comprises: a guiding tube adapted for insertion into the cardiovascular system. The guiding tube defines a lumen for sliding a guidewire therethrough. The catheter further comprises a tip pressure sensor eccentrically mounted relative to the guiding tube and a signal communication means extending therefrom. The tip pressure sensor is for sensing a pressure in the cardiovascular system and the signal communicating means is for transmitting a signal indicative of the pressure to a processing device in order to obtain a pressure measurement reading.

2011-03-17

20110066048

APPARATUS FOR EVALUATING VASCULAR ENDOTHELIAL FUNCTION - An apparatus for evaluating a vascular endothelial function, includes: a first cuff, to be wound around a first body part of a subject; a second cuff, to be wound around a second body part of the subject; a cuff pressure controller, configured to control a cuff pressure of each of the first and second cuffs, and configured to perform continuous pressure stimulation on the first body part of the subject for a time period by using the first cuff; a cuff pressure detector, configured to detect the cuff pressure of the second cuff from an output of a pressure sensor connected to the second cuff; a pulse wave detector, configured to detect, from the output of the pressure sensor, pulse waves before and after the continuous pressure stimulation is performed; and an analyzer, configured to evaluate the vascular endothelial function by comparing the pulse waves detected before and after the continuous pressure stimulation is performed.

2011-03-17

20110066049

PULSE ABNORMALITY DETECTING DEVICE - A pulse abnormality detecting device comprises a band attached to a wrist, a first sliding member with which the band is armored and which slides in the circumference direction of the band along the band, a second sliding member which is slidably provided on the first sliding member and which slides in the axis direction of the band, a pulse sensor which is provided on the second sliding member and which is provided in such a manner that the position of the sensor can be adjusted to the inner side or the side of the band, and a pulse abnormality detecting unit for detecting the abnormality of the pulse from the output data of the pulse sensor. The device can accurately detect the pulse of a user with high precision, adapting to a personal difference.

2011-03-17

20110066050

BODY-WORN VITAL SIGN MONITOR - The invention provides a body-worn monitor featuring a processing system that receives a digital data stream from an ECG system. A cable houses the ECG system at one terminal end, and plugs into the processing system, which is worn on the patient's wrist like a conventional wristwatch. The ECG system features: i) a connecting portion connected to multiple electrodes worn by the patient; ii) a differential amplifier that receives electrical signals from each electrode and process them to generate an analog ECG waveform; iii) an analog-to-digital converter that converts the analog ECG waveform into a digital ECG waveform; and iv) a transceiver that transmits a digital data stream representing the digital ECG waveform (or information calculated from the waveform) through the cable and to the processing system. Different ECG systems, typically featuring three, five, or twelve electrodes, can be interchanged with one another.

2011-03-17

20110066051

BODY-WORN VITAL SIGN MONITOR - The invention provides a body-worn monitor featuring a processing system that receives a digital data stream from an ECG system. A cable houses the ECG system at one terminal end, and plugs into the processing system, which is worn on the patient's wrist like a conventional wristwatch. The ECG system features: i) a connecting portion connected to multiple electrodes worn by the patient; ii) a differential amplifier that receives electrical signals from each electrode and process them to generate an analog ECG waveform; iii) an analog-to-digital converter that converts the analog ECG waveform into a digital ECG waveform; and iv) a transceiver that transmits a digital data stream representing the digital ECG waveform (or information calculated from the waveform) through the cable and to the processing system. Different ECG systems, typically featuring three, five, or twelve electrodes, can be interchanged with one another.

2011-03-17

20110066052

METHOD AND SYSTEM FOR REDUCING POWER LINE INTERFERENCES IN AN ECG SIGNAL - A method and system for correcting power line interferences in an ElectroCardioGram (ECG) signal is disclosed. The method comprises: providing an input signal having ECG signal along with interference signals to a digital filter capable of filtering at a preset frequency and identifying current power line frequency, if any, from the filtered input signal. The method further includes providing a look up table with index number for a set of frequency levels and corresponding filter coefficients, the set of frequency includes incremental steps in the range of possible variations on the power line frequency. The filter coefficient corresponding to current power line frequency is identified from the look up table. The digital filter is configured using the identified filter coefficient and the input signal is filtered using the re-configured digital filter.

2011-03-17

20110066053

ADAPTIVE SAMPLING - A method and apparatus is disclosed for adaptively sampling an analogue signal to increase the sampling rate in the presence of high frequency content within the signal, for example, QRS complex of an ECG signal. In one aspect, a change in a derivative of the analogue signal is used to control a voltage-controlled oscillator to provide a clock signal for an analogue-to-digital converter. The change in the derivative is compared to an automatically controlled threshold value. The clock signal controls the sampling rate of the analogue-to-digital converter so that the sampling rate is increased from one level, where only P and T waves are present to another higher level when the QRS complex has been detected.

2011-03-17

20110066054

METHOD AND ELECTRONIC MEDICAL DEVICE FOR SIMULTANEOUSLY MEASURING AN IMPEDANCE AND A BIOPOTENTIAL SIGNAL - A method and device is disclosed for continuously and simultaneously measuring an impedance signal and a biopotential signal on a biological subject's skin. In one aspect, the method includes attaching input and output electrodes to the biological subject's skin and applying a predetermined alternating current having a first frequency to the output electrodes for creating an alternating voltage signal over the input electrodes. The first frequency is above a predetermined minimum frequency. The method also includes measuring an input signal from the input electrodes which includes a biopotential signal and the alternating voltage signal. The method also includes extracting from the input signal the biopotential signal and the alternating voltage signal, and determining the impedance signal from the alternating voltage signal. The alternating voltage signal is extracted by amplifying and demodulating the input signal using a control signal having a frequency equal to the first frequency.

2011-03-17

20110066055

SYSTEM AND METHOD FOR USE WITH AN IMPLANTABLE MEDICAL DEVICE FOR DETECTING STROKE BASED ON PHYSIOLOGICAL AND ELECTROCARDIAC INDICES - Techniques are provided for detecting stroke within a patient using an implantable medical device. In one example, various electrocardiac and physiological signals are sensed within the patient by the implantable device. The device derives a set of indices from the sensed signals based on parameters affected by stroke. Stroke is then detected within the patient based on an examination of the set of indices. Warnings can then be generated, neurostimulation delivered, pacing therapy adjusted, medications dispensed, etc., in response to the stroke. In one particular example, the set of indices includes: a heart rate variability index; a heart rate turbulence index; a baroreflex index; a QT index; a respiration index; and a circadian variability index, from which a composite stroke index is derived. Time delta indices may also be generated for each individual index, which are exploited in generating the composite stroke index.

2011-03-17

20110066056

EXERCISE AUXILIARY DEVICE - The exercise auxiliary device comprises a body, a fastener, an ear-clip heart rate sensor, a microprocessor and an indicator. The fastener is mounted on the body for attaching the body to a garment on a user. The ear-clip heart rate sensor is adapted to clip an earlobe of the user, senses blood pulse from the earlobe and accordingly generates a voltage signal. The microprocessor is mounted in the body, electrically connected to the ear-clip heart rate sensor, computes an instantaneous heart rate according to the voltage signal. The indicator is connected to the microprocessor, controlled by the microprocessor to generate a reminding signal. The exercise auxiliary device can be easily worn by attaching the body to a garment of a user with the fastener and clipping an earlobe with the ear-clip heart rate sensor.

2011-03-17

20110066057

Electrical Angle Gauge - Methods of using electrodes to obtain physiological location motion data are provided. Embodiments of the methods include producing an electrode from a broadcasting electrode that is proximal to the physiological location of interest and detecting a change in an induced electric potential at a receiving electrode to obtain the motion data of interest. Also provided are systems and components thereof, e.g., programming, for practicing methods according to embodiments of the invention.

2011-03-17

20110066058

System and Method for Three-Dimensional Airway Reconstruction, Assessment and Analysis - This invention relates to a system and method for three-dimensional airway reconstruction, assessment and analysis. Specifically, the invention relates to a system and method for acquiring one- and two-dimensional data regarding a cavity, such as an esophagus or an airway, and manipulating that data to reconstruct a three-dimensional geometrical object representing that cavity. Suitable data collection methods include, but are not limited to, non-ionizing, non-invasive protocols including acoustic reflectometry, such as that performed by a DOS®- or Windows®-based pharyngometer or rhinometer. The resulting three-dimensional geometric object of the subject cavity can be used to diagnose cavity morphology/obstruction, aid in management and treatment of the obstruction, evaluate efficacy of management and treatment of the obstruction and also provide information for use in outcome analysis and forensic and medico-legal evaluation of diagnosis and treatment of cavity obstruction/stenosis.

2011-03-17

20110066059

SYSTEM AND METHOD FOR ANTICIPATING THE ONSET OF AN OBSTRUCTIVE SLEEP APNEA EVENT - Systems and methods for detecting a general breathing event and for anticipating an onset of an obstructive sleep apnea (OSA) event. The method for detecting a general breathing event includes receiving a plurality of signals from at least one microphone. The method also includes determining a one-sided power spectral density from the received signals. The method further includes distinguishing each received signal as either a breath signal or a background noise signal. The method still further includes calculating a breath signature by processing each breath signal.

2011-03-17

20110066060

APPARATUS AND METHOD FOR DIAGNOSTIC GAS ANALYSIS - A handheld, small but accurate and reliable device for diagnostic NO measurements using a NO sensor, where the parameters governing the taking of the sample are different from the parameters optimal for the accuracy of said NO sensor I described. By temporarily storing a portion of the exhaled air, and feeding this to the sensor at a flow rate adapted to the NO sensor, the accuracy and sensitivity of a system/method involving NO sensors, in particular electrochemical NO sensors, can be increased. The method for diagnostic NO measurements comprises steps for controlling the inhalation of NO free air, as well as the exhalation, both by built-in means and by audible and/or visual feedback to the patient.

2011-03-17

20110066061

WIRELESS CAPNOGRAPHY - According to some embodiments, there is provided a breath monitoring device and system that includes a patient interface unit, adapted to be positioned on the patient head, said patient interface unit comprises a cannula, adapted to collect a sample of exhaled breath from a patient; and a platform unit which includes: i. one or more CO

2011-03-17

20110066062

BODY-WORN MONITOR FOR MEASURING RESPIRATION RATE - The invention provides a multi-sensor system that uses an algorithm based on adaptive filtering to monitor a patient's respiratory rate. The system features a first sensor selected from the following group: i) an impedance pneumography sensor featuring at least two electrodes and a processing circuit configured to measure an impedance pneumography signal; ii) an ECG sensor featuring at least two electrodes and an ECG processing circuit configured to measure an ECG signal; and iii) a PPG sensor featuring a light source, photodetector, and PPG processing circuit configured to measure a PPG signal. Each of these sensors measures a time-dependent signal which is sensitive to respiratory rate and, during operation, is processed to determine an initial respiratory rate value. An adaptive digital filter is determined from the initial respiratory rate. The system features a second sensor (e.g. a digital 3-axis accelerometer) that attaches to the patient's torso and measures an ACC signal indicating movement of the chest or abdomen that is also sensitive to respiratory rate. This second signal is processed with the adaptive filter to determine a final value for respiratory rate.

2011-03-17

20110066063

Respiratory Inductive Plethysmography Band - The invention relates to improved apparatus and methods for respiratory inductive plesthysmography. The invention includes apparatus for measuring changes in the circumference of a subject comprising of an energisable conducting wire having two ends, engagement means for engaging said ends to form a gapless conducting loop, the engagement means being in electrical communication with the conducting wire. The relationship between the elements of the apparatus provides a reduced level of noise associated with a measureable signal attributed to the changes in circumference. Signals generated in the apparatus may be processed and communicated through various means for analysis of respiratory effort. A method is disclosed for measuring respiratory effort with a gapless conducting wire energised with current.

2011-03-17

20110066064

Method and System for Analyzing Breathing of a User - Methods, systems and apparatus for analyzing breathing of a user are disclosed. One method includes sensing motion of a first portion of the user, sensing motion of a second portion of the user, and generating a summed signal by inversely summing the sensed motion of the first portion of the user with the sensed motion of the second portion of the user. A breathing rate of the user is estimated based on the summed signal. Additionally, a breathing pattern of the user can be identified.

2011-03-17

20110066065

SYSTEMS AND METHODS TO IDENTIFY A SUBGROUP OF ADHD AT HIGHER RISK FOR COMPLICATING CONDITIONS - This invention is directed to embodiments of systems and methods to identify a subgroup of ADHD at higher risk for complicating conditions that, for example, may be of concern to an ADHD evaluation, may account for attention and behavior symptoms, and may lead a clinician to exclusion of ADHD from primary diagnosis. In one embodiment, a method for identifying a subgroup of attention deficit hyperactivity disorder (ADHD) patients at higher risk for complicating conditions is provided. The method can include receiving, from a user or clinician, evaluation data associated with a plurality of patients identified with ADHD as a primary diagnosis; obtaining EEG data for each of the plurality of patients; determining, based at least in part on the EEG data, an indicator of ADHD, wherein the indicator supports a positive or negative ADHD evaluation; correlating the indicator with a user's or clinician's evaluation data; and based at least in part on the correlation, determining at least one subgroup of the plurality of patients, wherein the correlation provides positive support for diagnosis of ADHD or provides support for further testing for complicating conditions before proceeding with diagnosis of ADHD in at least one patient within the at least one subgroup.

Methods for Diagnosis and Treatment of Processing Difficulties, Integration Problems, Imbalances and Abnormal Postures - Methods for diagnosis and treatment are provided for a patient having processing difficulties, integration problems, imbalances or abnormal postures. In one embodiment, a patient is identified having retinal signal problems creating at least one negative medical condition. Then the amount of a natural hormone in the eye is increased such that, as a result of the diagnosis and treatment, the patient achieves improved retinal signal processing and at least one of the patient's negative medical conditions is improved. Other embodiments include using the treatment in combination with the Z-Bell Test and/or light blocking or altering devices for diagnosis and treatment.

METHOD AND SYSTEM FOR QUANTITATIVE ASSESSMENT OF VISUAL MOTION DISCRIMINATION - A method is presented to address quantitative assessment of visual motion discrimination in a subject, where the method comprises the steps of: (1) presenting a scene, comprising a plurality of elements and a background, to a subject on a display; (2) moving a plurality of elements relative to the scene; (3) receiving feedback from the subject; (4)quantitatively refining the feedback; (5) modulating the movement relative to accuracy of the received feedback; (6) monitoring the response error; (7) calculating a critical threshold parameter for the subject; and (8) recording a critical threshold parameter onto a tangible computer readable medium. An apparatus for quantitative assessment of visual motion discrimination of a subject comprising a display device, an input device, a control device, and a tangible computer readable medium. In its simplest sense, a quantitative assessment profile of visual motion discrimination by psychophysical responses is generated on a tangible computer readable medium.

INTRACRANIAL PRESSURE SENSOR - An intracranial pressure device for measuring CSF pressure in a skull includes a housing located between the scalp and the skull containing pressure device circuitry and a conduit extending downwardly from the housing to the vicinity of the CSF. A pressure sensor is coupled to the conduit and located in communication with the CSF wherein the pressure sensor directly senses the pressure of the CSF and provides a signal representative of the pressure of the CSF to the pressure device circuitry by way of the conduit. The skull has a dura and the conduit extends by way of an opening through the skull and an opening through the dura to position the sensor in direct contact with the CSF. A fluid reservoir can be in communication with the CSF by way of a tube and by way of the housing. The fluid reservoir contains CSF.

2011-03-17

20110066073

BIOPSY DEVICE WITH ACOUSTIC ELEMENT - The invention relates to a biopsy device, particularly a biopsy device comprising a shaft with a transducer element for providing information about acoustic properties of a material to be analysed, a system of positioning a biopsy device and a method for positioning a biopsy device. The biopsy device may be adapted to take biopsies of different regions of the 5 human body for excluding or detecting abnormalities as cancerous lesions. The biopsy device may be used to measure acoustic properties of the material while inserting the tip portion of the biopsy device into the material to be analysed. The biopsy device may further allow measurement based on elastography.

2011-03-17

20110066074

Filter for Fine Needle Biopsy - A biopsy needle comprises a first lumen open to a tissue penetrating distal tip of the needle for receiving a tissue sample therein and a second lumen in combination with a filter separating the first and second lumens from one another, the filter being configured to permit fluids to pass therethrough while preventing the sampled tissue from passing therethrough.

2011-03-17

20110066075

Device for Biopsy of Tumors - A device and method of use for securing and coring of tumors within the body during a biopsy of the tumor, specifically breast tumors. An adhesion probe for securing the tumor is described. The probe secures the tumor by piercing the tumor and providing a coolant to the distal tip to cool the tip. The cooled tip adheres to the tumor. A coring instrument adapted for cutting a core sample of the tumor is described. The instrument is provided with a cannula that can cut a core sample of the tumor. The instrument is adapted for use with the probe with the probe fitting within the cannula. The instrument can be used in conjunction with the probe to secure and core a sample of the tumor for biopsy.

BLOOD SAMPLING NEEDLE - A blood sampling needle has a shell, a trigger seat, a needle stand, an elastic resetter and a safety switching member. The shell is provided with inner wall, retaining space, needle outlet and insertion end. A through-flange is formed into the shell. The through-flange and inner wall form a release groove with a tapered end-face. The trigger seat is mounted into the retaining space in a moveable state. The trigger seat has a control end and a rod. An axial chamber is opened on the rod so that two elastic release blades are formed on the rod, and also accommodated correspondingly into the release groove. An abutting bevel edge is formed at the bottom of the elastic release blade, and mated with the tapered end-face of the release groove in an oblique surface. The present invention saves structural members, reduces fabrication cost with better safety and applicability.

2011-03-17

20110066078

PAIN MONITOR FOR A PATIENT UNDERGOING A MEDICAL PROCEDURE - A pain monitor for a patient undergoing a medical procedure includes a housing adapted to fit in a hand of the patient, a force sensor, and a battery-powered data processor. The patient is instructed to squeeze the housing with a force representing his level of pain. That force is measured by the sensor, acquired by the data processor and then wirelessly transmitted to an outside data receiver for further processing and recording. This device allows the patient to non-verbally express his perception of the level of pain which in turn allows a physician to adjust the course of the procedure or the level of pain-reducing medication. The pain monitor of the invention is particularly useful during a colonoscopy procedure.

2011-03-17

20110066079

PROSTHETIC DEVICE AND SYSTEM AND METHOD FOR IMPLANTING PROSTHETIC DEVICE - A prosthetic device includes one or more components configured to be disposed in a joint. The component includes at least one feature configured to provide information about the component. The information can be used to determine or create the relationship between the component and the joint and/or other components. This relationship may be used to evaluate and/or modify the expected performance of the prosthetic device and assist in determining the optimal relationship between one or more components and a patient's anatomy.