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The Antibody Molecule follows the extraordinary journey of the medics and scientists who shaped the course of medical advances in the field of immunology. One of the oldest of the medical ...
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The Antibody Molecule follows the extraordinary journey of the medics and scientists who shaped the course of medical advances in the field of immunology. One of the oldest of the medical sciences, immunology has a history that has seen chemists, physicists and biologists alike seeking to unravel the most complex system in the human body outside the brain. This title charts its intriguing history, from the genetic basis of antibody diversity, through the understanding of the mechanism by which the immune system's first line of defence works, to breakthroughs in crystallography and the exploitation of immunoglobulins as therapeutic platforms to treat cancer, inflammation and allergy. Tracing the developments in immunology in chronological order, Professor Anthony R. Rees presents the historical contexts of the periods in rich detail, bringing them to life with quotes and illustrations.Less

This resource provides a concise, up-to-date, and readable account of immunology in general and its translation into key areas of clinical practice. It provides the necessary foundation for ...
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This resource provides a concise, up-to-date, and readable account of immunology in general and its translation into key areas of clinical practice. It provides the necessary foundation for a critical understanding of this essential and rapidly expanding area of biological science that underpins and explains the modern concepts of a range of diseases and conditions, encompassing autoimmunity, infection, trauma, cancer, nutrition, organ transplantation, and various forms of therapy.Less

While there have been a large number of recent textbooks dealing with tuberculosis in adults, usually with minimal or no content relevant to pediatrics, and there have been several ...
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While there have been a large number of recent textbooks dealing with tuberculosis in adults, usually with minimal or no content relevant to pediatrics, and there have been several textbooks on childhood tuberculosis with distribution limited mostly to India and South Africa, there has not been a widely distributed book on childhood tuberculosis since 1963. We have assembled a group of internationally recognized clinicians, researchers and authors to create a modern handbook of childhood tuberculosis. This book covers all aspects of childhood tuberculosis including: the natural history of childhood tuberculosis and the history of its scientific study; microbiology and laboratory testing for Mycobacterium tuberculosis and Mycobacterium bovis; epidemiology; clinical and radiographic presentations of intra- and extra-thoracic tuberculosis; diagnosis and treatment of tuberculosis infection; diagnosis and treatment of drug-susceptible and drug-resistant tuberculosis disease; management of tuberculosis in newborns, adolescents and children with HIV infection; BCG vaccines; public health and infection control aspects of childhood tuberculosis; and the World Health Organization Roadmap for Childhood Tuberculosis. We highlight those aspects of tuberculosis that are unique to children and adolescents and principles that have practical applications through the use of algorithms, figures and tables to emphasize key points and encourage standardization of practice, when possible. This book is intended for use by clinicians, researchers and policy makers to ensure that the needs of children and adolescents with tuberculosis are met throughout the world.Less

These case studies illustrate infections encountered in hospitals among patients with compromised immune systems. As a result of immunocompromise, the patients are vulnerable to common and ...
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These case studies illustrate infections encountered in hospitals among patients with compromised immune systems. As a result of immunocompromise, the patients are vulnerable to common and uncommon infections. These cases are carefully chosen to reflect the most frequently encountered infections in the patient population, with a specific emphasis on illustrations and lucid presentations to explain state-of-the-art approaches in diagnosis and treatment. Common and uncommon presentations of infections are presented while the rare ones are not emphasized. The cases are written and edited by clinicians and experts in the field. Each case highlights the immune dysfunction that uniquely predisposed the patient to the specific infection, and the cases deal with infections in the cancer patient, infections in the solid organ transplant recipient, infections in the stem cell recipient, infections in patients who receive immunosuppressive drugs, and infections in patients with immunocompromise that is caused by miscellaneous conditions.Less

Landmark Papers in Allergy is a definitive collection of over 90 papers charting key discoveries in relation to allergy and the development of treatment and care for allergic disorders. ...
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Landmark Papers in Allergy is a definitive collection of over 90 papers charting key discoveries in relation to allergy and the development of treatment and care for allergic disorders. Commentaries from leading international experts provide reflections on the historical importance and current relevance of each contribution.
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The medical management of infectious diseases and antimicrobial therapy can be a daunting task for health care professionals. Although expansive textbooks and online resources are ...
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The medical management of infectious diseases and antimicrobial therapy can be a daunting task for health care professionals. Although expansive textbooks and online resources are available, we believe that a more simplified, quick reference guide is needed for the day-to-day office and hospital clinical practice. This book is designed to provide information about infectious diseases and antimicrobial therapy in a format that is readily accessible and easily applicable to the clinical environment. Highlights of this book include simplified and thorough drug dosing recommendations for renal function and renal replacement therapies, drugs of choice for specific organisms (including bacteria, fungi, and viruses), and simplified antimicrobial and management recommendations for specific infectious syndromes.Less

Part of the What Do I Do Now?” series, Neuroimmunology uses a case-based approach to cover common and important topics in the examination, investigation, and management of central and ...
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Part of the What Do I Do Now?” series, Neuroimmunology uses a case-based approach to cover common and important topics in the examination, investigation, and management of central and peripheral demyelinating diseases, vasculitis, and other immune system related neurological disorders. Each chapter provides a discussion of the diagnosis, key points to remember, and selected references for further reading. For this edition, all cases and references have been updated and new cases have been added, including POEMS, CASPR2 Antibody Syndrome, Isaac’s Syndrome, Histiocytosis, and Churg-Strauss. Neuroimmunology is an engaging collection of thought-provoking cases which clinicians can utilize when they encounter difficult patients. The volume is also a self-assessment tool that tests the reader’s ability to answer the question, “What do I do now?”Less

The Oxford Handbook of Clinical Immunology and Allergy is a unique, practical and clinically relevant guide for clinicians and laboratory staff to assist with the diagnosis and management ...
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The Oxford Handbook of Clinical Immunology and Allergy is a unique, practical and clinically relevant guide for clinicians and laboratory staff to assist with the diagnosis and management of immunological/allergic disease, and the correct selection and interpretation of immunological tests, and has been expanded to include the latest developments, drugs, diagnostic tests, and therapy options in the field.Less

This resource provides an up-to-date and comprehensive account of cancer immunity and immunotherapy, and discusses our adaptive and innate immunity to cancer, the mechanisms underpinning ...
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This resource provides an up-to-date and comprehensive account of cancer immunity and immunotherapy, and discusses our adaptive and innate immunity to cancer, the mechanisms underpinning our immune response, current approaches to cancer immunotherapy, and how tumour and host responses can circumvent effective anti-cancer immunity. It then examines recent results, publications and current areas of interest including 'immune editing' and the specific issues that are affecting the research and development of vaccines, providing insight into how these problems may be overcome.Less