We know Huddy fans don't want to think about it, but who could ever replace her? It's possible they could promote from within, but they probably don't want to ruin the team dynamic either. And if they bumped Wilson up to bossman status, that would certainly complicate his friendship with House even more.

So we've come up with a list of strong contenders ... all women, as it turns out, so I guess we like that sexual tension, too. I mean, someone's gonna have to be the soft feminine shoulder for House to cry on when his favorite sparring partner says goodbye, right?

Following in the impressive footsteps of 'Lost' and 'Fringe', starting a series on an airplane isn't necessarily the most original way to begin a new television journey.

However, 'The Event' (Mon. 9PM ET, NBC) proves to be an entirely different show and establishes itself as a unique viewing experience within the first three episodes. Ratings are obviously a major factor, but there are four other essential ingredients that will determine the fate and future of 'The Event.'

In 'The Event,' Laura Innes plays Sophia Maguire, a woman who's been held in a secret government facility and who may know more about what's going on in the series than anyone else. But Sophia isn't ready to spill the beans, and neither was Innes when she appeared on 'Today' (Weekdays, 7AM on NBC). "We cannot tell," she told co-hosts Hoda Kotb and Kathie Lee Gifford. Innes is so committed to the secrecy, she won't even tell her 9-year old daughter.

But Innes almost missed out on the mysteries herself. "They had called me about a particular part," she said. "And it wasn't that interesting to me." That was until the producers suggested they might change one particular character into a woman. "That was very, very intriguing to me," Innes admitted. "Because [Sophia]'s sort of the hub of the mystery."

'The Event' is a new conspiracy-mystery-thriller-adventure ensemble drama that kicks off its own brand of mythology 9PM ET Monday on NBC. Opinions vary on whether America is clamoring for another one of those.

If my opinion on the drama (which is below) isn't enough for you, I've also gotten some intel on 'The Event' from creator Nick Wauters; exclusive video and casting news follows. Wauters explained how the show will progress and evolve, how it will be augmented with online content, and how he and the show's writers plan to avoid making viewers feel like Charlie Brown after Lucy has pulled the football away.
Ten Things to Know About 'The Event':

I have absolutely no idea, but that's why 'The Event' is so intriguing. Mixing elements of hit sci-fi shows like 'Lost' with the addictive serialized nature of a '24,' the new NBC series (premieres Mon., Sept. 20, 9PM ET) follows a number of intriguing characters on all sides of a mysterious, possibly supernatural occurrence.
The stars of the show -- including Jason Ritter, Laura Innes, Blair Underwood, Scott Patterson and Zeljko Ivanek -- can't say too much for fear of network snipers, but I tried to get as much out of them as I could. The result? Even more intrigue, I think -- are you excited to watch?

'The Event' deals with a young man -- Jason Ritter -- who's thrust into the middle of mystical game of espionage as he tries to find his missing girlfriend.

Most of the panel for the NBC series that's best described as part 'Lost' and part '24' was taken up by the screening of the show's pilot. Fans had only about 15 minutes for a moderator-conducted Q&A with the ensemble show's cast, which is headlined by Jason Ritter, Blair Underwood and Laura Innes.

But the good news is that If the crowd reaction was any indication, THIS is the must-see series of the fall. If you're still going through Jack Bauer and Jack Shephard withdrawal, trust us -- Ritter's Sean Walker is your new hero.

Each act break ended on a compelling cliffhanger, the biggest one was saved for the end of the show. Kudos to producers for informing viewers as to when a scene was set by starting each one off with "eight days ago" or "13 hours ago." It would be nice if 'Lost' had done that all shows with big casts and lots of flashbacks would do that.

Creator Nick Wauters explained that there are definitely elements of "mystery, sci-fi, thrillers, and a love story" to 'The Event.' "We wanted to create something that' has a little bit of something for everyone."

'ER's' David Lyons, Shane West and Laura Innes have each booked pilots on NBC and the CW. According to reports, Lyons will lead NBC's 'The Cape,' about an ex-cop who becomes a superhero in an attempt to fix his reputation and reunite with his son. Over at the CW, West will join Maggie Q in the upcoming reboot of 'Nikita,' while Innes will create an 'Event' at NBC, playing the head of the inmates at a "secret facility." [Hollywood Reporter]

But it was a pretty good finale anyway. It's impossible to please all fans of a long-running show in a series finale because we expect too much, and what we expect can change depending on whether you've been watching it since the beginning or just started four years ago. Do they focus on the old cast members coming back and focus on the people who have been there for the past few years? Do they tie up all loose ends neatly in a bow or leave things open-ended because that's how life is? ER managed to do both last night.

Yup, tonight is the final ER. NBC will have an hour-long retrospective at 8 PM and then the two-hour season finale of the show at 9 PM (sorry, fans of My Name Is Earl, The Office, and 30 Rock). We've seen several old favorites come back this season in previous episodes, and we know that a couple more are coming back for tonight's last hurrah. Will George Clooney be one of them?

Clooney already made an appearance on the show with Juliana Margulies a few weeks ago, and I liked the episode enough. It's just that there was a slight something missing from the episode, something concerning Doug and Carol and them not knowing that the kidney going to County General was for Carter.

So this Thursday at 9pm, the series finale ofERairs on NBC. I think that even former fans who drifted away from the show when Anthony Edwards was killed off, or when Noah Wyle left, or when they just didn't enjoy the show anymore because it had been on for too long will tune into the finale. You can't watch a show for so many years and then just forget all about the finale. The thing has been on since Bill Clinton's first term, so we gotta find out how it ends.

The episode (like this season in general) will also have some familiar faces coming back to County General, and probably some in pictures and/or flashbacks (the episode will be preceded by a retrospective at 8pm). After the jump, a video sneak peek at the episode (and, yes, there are possible spoilers, so proceed with caution!)

Juliana Margulies, who played Nurse Carol Hathaway on the show before she and Clooney walked off into the sunset in a surprise scene in her last episode, has agreed to come back to the show too. She and Clooney are going to film their scenes later this week. Margulies joins Anthony Edwards, Laura Innes, Alex Kingston, Paul McCrane, Abraham Benrubi, who have already made return engagements this season, and Noah Wyle, William H. Macy, and Eriq LaSalle. who are still to come (Gloria Reuben made an appearance last season). You know who'd I'd like to see return to the show one last time? Sherry Stringfield. Susan Lewis was one of my favorite characters.

Yet another ER veteran is coming back to the show for a last-season guest spot.

Alex Kingston will reprise her role as Dr. Elizabeth Corday in the January 15 episode. She'll come back when Neela has to interview with her for an attending job. If you remember, Corday was married to Dr. Mark Greene but inevitably had to leave the show after he died and there really wasn't much for her to do (those episodes where she dated others just didn't ring true).

Seems like we've been hearing news about old ER members coming back to the show for its final season, and now comes word from Juliana Marguiles. The actress says that she won't be coming back to the show because she thinks that Carol Hathaway left on a good note and she really can't see how they could top it. A lot of fans would probably say they don't want them to top the character's last appearance, they just want to see the character one more time before the series fades off into the sunset.

Tonight's the night that thousands of fans of ER have been waiting for, the return of Jennifer Aniston! Oh wait, that's 30 Rock that she'll be on tonight. Never mind.

Actually, tonight is the night that Dr. Mark Greene (Anthony Edwards) returns to County to try to save the life of Dr. Banfield's sick son. As we told you last week, Greene isn't really alive and he's not a ghost. It seems that Dr. Banfield came to County with her son and husband, years before she became the new head of the ER, and Greene was the doctor who worked on her son. Her memory (and the flashbacks) are triggered by a current story where Banfield is trying to save the life of another child who comes to County.

Edwards isn't the only one who comes back. Since most of the episode takes place years ago, we also see Laura Innes as Dr. Weaver and Paul McCrane as Dr. Romano. Innes has a rather dramatic entrance in the clip after the jump!