The Novo Nordisk Foundation Centers for Stem Cell Biology (DanStem) and Protein Research (CPR) at the University of Copenhagen are jointly seeking applications for a 2-year position of Bioinformatics Specialist.

The Novo Nordisk Foundation Center for Stem Cell Biology (DanStem) addresses basic research questions in stem cell and developmental biology and has activities focused on the translation of promising basic research results into new therapeutic strategies for cancer and chronic diseases. Learn more about DanStem at https://danstem.ku.dk/.

The Novo Nordisk Foundation Center for Protein Research (CPR) promotes basic and applied research on proteins of medical relevance. Spanning in silico biology, proteomics, biochemistry and cell biology, and the unifying research theme is the identification and functional exploration of proteins and protein pathways involved in disease. Learn more about CPR at www.cpr.ku.dk.

Background

Both DanStem and CPR are vibrant, internationally diverse and ambitious research centers housing modern laboratories with state-of- the-art facilities located in close proximity to one another at the Faculty of Health and Medical Sciences, University of Copenhagen. The setting is ideally suited for seamless collaboration and exchange of expertise, material and lively scientific communication. DanStem and CPR collaboratively operate three research platforms in imaging, flow cytometry and genomics. These platforms are staffed with experts who provide advanced training and tailored project planning and assistance. The Genomics Platform provides high-throughput sequencing services with personalized support, covering applications from classical genomics to single-cell transcriptomics and has generated a demand for bioinformatics support. Therefore, the Centers intend to develop a new informatics platform to full fill the need of bioinformatics and computational approaches to data analysis enhancing the scientific synergies between the two centers.

We are now seeking a highly motivated and qualified bioinformatician with specialty in genomics to work within the Informatics Platform at DanStem and CPR.

Responsibilities

The Bioinformatics Specialist will provide bioinformatics support, develop new pipelines, and organize practical training to assist DanStem and CPR researchers with analysis and interpretation of primarily genomics data. The bioinformatician will work within the newly developing Informatics Platform, as well as with the dedicated sequencing specialist to provide tailored service and support for multiple research projects of broad biomedical scope throughout the two research centers.

This Bioinformatics Specialist is expected to:

Develop tailored bioinformatics approaches and provide advice and assistance to DanStem and CPR researchers in their analyses, focusing in particular on the planning, processing, analysis and publication of transcriptomic and epigenomic next-generation sequencing data.

Prepare pipelines and scripts for use by DanStem and CPR researchers.

Provide training and design new approaches to analysis.

Cooperate and collaborate with DanStem and CPR researchers.

Cooperate with platform personnel and contribute to platform management.

Network actively with the global bioinformatics community and stay up-to-date with current trends in the field.

Similar to our other platform specialists, the Bioinformatics Specialist will sit at the nexus of the two centers. To ensure good support and guidance, the NGS Bioinformatics Specialist will work closely with the Big Data Management Platform at CPR, which handles data from other technology platforms, as well as among research groups that cover many systems-level aspects of biology and medicine, including the integration of molecular level and healthcare data.

Qualifications, competences and experience

Candidates are expected to have a Master’s or PhD degree in bioinformatics, computational genomics or biology, computer science and data analysis, or a biological or natural sciences discipline, with at least four years of experience in bioinformatics for genomics. In addition, we are seeking a candidate with the following competences and experiences:

Fluent programming skills in R/Bioconductor.

Experience with next generation sequencing data.

Strong statistics skills.

Knowledge of UNIX-like operating system.

Experience in working with biologists and an understanding of molecular biology and genomics.

Excellent oral and written communication skills and fluency in English.

State-of-the-art computational infrastructure for data analysis, including access to cluster computing at the Danish National Supercomputer (Computerome) and excellent IT and systems administration support.

Stimulating and multifaceted research environment of high scientific and societal impact.

Possibility for continued education and training, especially to develop further as an expert in single cell bioinformatics.

With an initial duration until the end of 2020 with possibility of extension, employment can begin in November 2018 or upon agreement with the chosen candidate. The place of work is at DanStem, University of Copenhagen, Blegdamsvej 3B, Copenhagen. The position, with formal employment title of Senior consultant at the University of Copenhagen, will be in accordance with provisions of the collective agreement between the Danish Confederation of Professional Associations (AC/PROSA) and the Danish Ministry of Finance. To the salary is added a monthly contribution to a pension fund according to the collective agreement. A supplement could be negotiated, depending on the candidate’s experiences and qualification.

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