Tag Archives: aldol

Researchers at Gifu Pharmaceutical University led by Prof. Tsuyoshi Miura have been working on fluorous sulfonamide organocatalysts for some time now and have reported their results in various reactions. These include asymmetric aldol reactions and Michael additions which we have … Continue reading →

The Cai group at Nanjing University have been ardently pursuing various fluorous catalyst and tagging methods for small molecule synthesis. They’ve added to their body of work with a new publication in J. Fluorine. Chem. describing the use and recovery … Continue reading →

Fluorous tagged organocatalysts have been used by several groups to facilitate the removal, recovery, and reuse of these important class of catalysts from post reaction mixtures. For previous F-Blog posts regarding organocatalysts, please click here. The Miura group at Gifu … Continue reading →

A short commentary on two other recent reviews. The first is a mini-review from Kumar and Waldmann entitled “Synthesis of Natural Product Inspired Compound Collections” in Angewandte Chemie. If it sounds familiar, it should, because it’s essentially the same subject … Continue reading →

Aldol condensation is one of the most fundamental and important carbon-carbon bond-forming reactions wherein an enolate ion reacts with a carbonyl compound to form a beta-hydroxyaldehyde or beta-hydroxyketone which upon dehydration results in a conjugated enone. The reactions are usually … Continue reading →