Take I-75 and get off at Exit 123, heading east on Corkscrew road, until it ends at 82/Immokalee Road, Take a right on 82, take a right on 29 and head towards Immokalee, left onto CR 846. Follow this road into Hendry County, until it intersects with CR 833, Take a right on CR 833 and follow it into the Big Cypress Reservation.

Take US-27 North to I-75 North (toward Naples -Toll Road), take Exit 49/Snake Road North 17 miles.

FROM CLEWISTON/MOORE HAVEN
40 MIN.

Take SR-80 to the intersection of SR-80 and US-27, Continue on SR-80 to LaBelle/Ft. Myers, make a left onto CR-833 (Big Cypress Reservation), Follow CR-833 for approximately 29 miles until you reach the Big Cypress Reservation (Please note, there will be two sharp turns on CR-833, but do not get off the highway. Just follow until you cross the Reservation line), CR833 becomes N. Boundary Road as you enter the Reservation.