Watching a Great Dane cower in fear of a Chihuahua never gets old.

You often hear that size doesn't matter. Usually, it's when women are lying to men in order to make them feel better. When it comes to dogs, it's actually true. Of course, size would matter during an actual fight. That's why tiny Chihuahuas make sure it never gets to that point by posturing as lean, mean flesh-eating killers that would tear off your toes for looking at it sideways.

Great Danes, on the other hand, seem to offset whatever size advantage they may have by being, pound-for-pound, the biggest babies in the animal kingdom. That's certainly the case with Duke, the 105-pound dog who, when confronted by a 3.5 pound visitor, made a beeline for the safety of his owner's lap.