JAMA Pediatrics: Rhinoplasty Topic Collectionhttp://archpedi.jamanetwork.com/
en-usMon, 24 Dec 2012 00:00:00 GMTTue, 01 Jan 2013 00:51:51 GMTSilverchaireditor@archpedi.jamanetwork.comwebmaster@archpedi.jamanetwork.comPathological Case of the Monthhttp://archpedi.jamanetwork.com/article.aspx?articleID=349348
Mon, 01 May 2000 00:00:00 GMTMeadows KP, Egan CA, Vanderhooft SL. <span class="paragraphSection">A 4-YEAR-OLD white girl had an enlarged frontal bone at birth. She had reconstructive surgery, and findings from bone biopsy showed fibrous dysplasia. Physicians in the dermatology department were consulted because of an 18-month history of "growths" on both feet. On examination, she had a dysmorphic facies with frontal bossing and a broad nasal root. An epidermal nevus followed Blaschko lines on the right posterior neck (<a href="#ppc8081f1" class="reflinks">Figure 1</a>). There was cerebriform hyperplasia of both soles, with macrodactyly most notable on the right second toe (<a href="#ppc8081f2" class="reflinks">Figure 2</a>). A faint port-wine stain was also observed on the left upper lateral thigh. A specimen from shave biopsy was obtained from the hypertrophic soft tissue on the toe. There was marked, dense, dermal fibrosis with mild disorganization and minimal cellularity (<a href="#ppc8081f3" class="reflinks">Figure 3</a>). The fibrosis was well visualized by trichrome stain (<a href="#ppc8081f4" class="reflinks">Figure 4</a>).</span>154552752810.1001/archpedi.154.5.527http://archpedi.jamanetwork.com/article.aspx?articleID=349348