The history of Yangzhou University Medical college can be traced back to as early as 1950. The predecessor of the college is Subei Health School, which was grown into Yangzhou in 1958 and then Yangzhou medical college in 1984. In 1992, Yangzhou medical college, together with other 5 college, was enrolled to found Yangzhou University and became Yangzhou University Medical college.

Yangzhou University Medical college consists of five bachelor's degree programs including clinical medicine, traditional Chinese medical science, clinical discipline of Chinese and western integrative medicine, nursing and pharmacy. The professional emphasis of obstetrics and gynecology and dermatology and sexually transmitted diseases prevention which belong to clinical medicine have high influence in and out of Jiangsu province. From 2006, five-year international undergraduate professional in clinical medicine were enrolled who were taught using English only.

The college owns 1 first-level doctorate program (Chinese and western integrative medicine), 7 first-level master's programs (Basic medical sciences, Clinical medicine, Nursing, Preventive medicine, Pharmaceutical sciences, Chinese and western integrative medicine, and Chinese materia medica), 45 second-level master's programs (human anatomy and histoembryology, physiology, immunology, pathology and pathophysiology, pharmacology, internal medicine, surgery, obstetrics and gynecology, dermatology and sexually transmitted diseases prevention, medical imaging and nuclear medicine, science of Chinese traditional medicine, basic and clinical discipline of Chinese and western integrative medicine, ect.) and two professional degree programs (Clinical medicine and Chinese materia medica). Our college is among the colleges that were authorized by Ministry of Education to enroll foreign undergraduate student of clinical discipline. The Chinese and western integrative medicine is the key discipline at provincial level, and 13 disciplines (digest Internal medicine, cardiology, haematology, osteology, neurology, medical imaging and nuclear medicine and general surgery, ect.) are the key clinical specialties at provincial level. It possesses state-level endoscopy training center of Ministry of Health, and counseling psychology training base of the Ministry of Human Resources and Social Security of China. For now, there are 2210 full-time undergraduate, 468 master degree candidates and doctoral candidates and 48 overseas students in the college.