Select valve for liquid chromatography11/06/14 - 20140326664 - A liquid chromatography system includes a pumping system with a selector valve in fluidic communication with a pump inlet. The selector valve switches between a first position, in which the selector valve fluidically couples a solvent reservoir to the pump inlet, and a second position, in which the selector valve...

Method and system for liquid chromatography fluidic monitoring10/09/14 - 20140299542 - A method for monitoring a fluidic system of a liquid chromatography system is characterized by: (a) drawing a fluid into a syringe pump; (b) configuring a valve so as to fluidically couple the pump to either a fluidic pathway through the fluidic system or to a plug that prevents fluid...

Mixed-mode chromatography membranes08/28/14 - 20140238935 - Described are composite materials and methods of using them for mixed-mode chromatography. In certain embodiments, the composite material comprises a support member, comprising a plurality of pores extending through the support member; and a multi-functional cross-linked gel. The multi-functional cross-linked gel possesses at least two of the following functions or...

Reducing dispersion due to vias in planar microfluidic separation devices05/22/14 - 20140138312 - A planar microfluidic chemical separation device includes a separation channel that is located in the plane of the device. The device also includes one or more vias situated perpendicular to the separation channel. The vias extends between the separation channel and an outer surface of the substrate for fluid communication...

Device and method for restoration of the condition of blood05/15/14 - 20140131276 - The present invention relates to a device for extracorporeal removal of harmful agents from blood or blood com-Components, comprising full length heparin immobilized on a solid substrate by covalent end point attachment. The present invention also relates to a method for extracorporeal removal of a harmful agent from mammalian blood...

Closed loop flow control of a hplc constant flow pump to enable low-flow operation05/15/14 - 20140131277 - A method and apparatus for monitoring and controlling nano-scale flow rate of fluid in the operating flow path of a HPLC system provide fluid flow without relying on complex calibration routines to compensate for solvent composition gradients typically used in HPLC. The apparatus and method are used to correct the...

Removal of elements from aqueous fluids05/01/14 - 20140116940 - Methods of removing ions from an aqueous fluid can comprise increasing the pH of the aqueous fluid and contacting the aqueous fluid with anion exchange materials....

Method for removing biopolymer aggregates and viruses from a fluid05/01/14 - 20140116941 - The present invention relates to a method for removing biopolymer aggregates and viruses from a fluid. In a first step, the biopolymer aggregates are selectively removed by filtration through a porous, polyamide-comprising shaped body having a native surface. In a second step, the biopolymer aggregate-free fluid is filtered through at...

Countercurrent chromatography rotor04/03/14 - 20140091036 - A method for constructing a spiral tube support apparatus used in countercurrent chromatography, improvements to countercurrent chromatography tube support design, and methods of using the improved countercurrent chromatography apparatus are described. The spiral tube support apparatus may be constructed by a shape forming process such as a three dimensional printing...

Mobile phase preparation device for liquid chromatography03/06/14 - 20140061128 - A mobile phase delivery device for use with high pressure liquid chromatography includes a manifold having a plurality of inlets, wherein each inlet is fluidly coupled with a solvent source. The manifold further has a mobile phase outlet that outputs a mobile phase, composed of solvent or solvent mixture, onto...

Method and apparatus for reaction chromatography11/21/13 - 20130306558 - An apparatus for reaction chromatography comprising: a chromatography column, the column having a fluid outlet for an eluate flow, wherein the fluid outlet is configured with two or more fluid ports, the two or more fluid ports comprising one or more reactant ports, wherein each reactant port is for connecting...

Gradient separation method transfer for liquid chromatography systems09/05/13 - 20130228513 - Described is a method of transferring a gradient separation method to a liquid chromatography system. A value of a delivered gradient slope for a gradient separation method performed on a first liquid chromatography system is determined based on a value of a programmed gradient slope for the gradient separation method...

Chromatography system with guard columns08/22/13 - 20130213884 - A chromatography system with a main column comprising a chromatography resin, a first guard column and a second guard column, wherein the first guard column is connected to a first end of the main column, the second guard column is connected to a second end of the main column and...

Methods and materials for performing hydrophobic interaction chromatography05/24/12 - 20120125843 - A method for performing hydrophobic interaction chromatography includes providing at least one wall defining a chamber having an inlet and an exit, and a stationary phase disposed within the chamber. The stationary phase comprises particles or monolith having a hydrophobic surface and a hydrophilic ligand. The method also includes loading...

Sol-gel monolithic column with optical window and method of making01/05/12 - 20120000850 - A method of preparing a sol-gel monolithic column includes the step of forming a separation bed (14) from a sol-gel solution in a single process step. This column has improved characteristics for CEC based on its incorporated surface charge and ease of operation due to a lack of or need...

Liquid chromatography apparatus and liquid chromatography08/04/11 - 20110186511 - A liquid chromatography apparatus is provided with a sample preparation unit, a column that separates components of a sample, an eluent supplier that includes a feeder for supplying eluents to the column, a flow path directional valve capable of introducing fixed amounts of the sample and the eluents to the...

Method and device for chromatographic purification02/24/11 - 20110042310 - A process for continuous or quasi-continuous purification of a multi-component mixture (F) by means of individual chromatographic columns through which the mixture is fed by means of at least one solvent(s). The multi-component mixture (F) at least comprises light impurities (A), an intermediate product (B) to be purified and heavy...

Selective sulphate removal by exclusive anion exchange from hard water waste streams12/09/10 - 20100307972 - The invention provides waste water treatment processes utilizing an ion exchange resin to remove sulphate anions, while adjusting the pH of the ion exchange loading solution with carbon dioxide gas. The effect of the resin loading reactions is that dissolved sulphate is replaced with sequestered carbon dioxide gas, in the...

Templated native silk smectic gels11/25/10 - 20100294716 - One aspect of the present invention relates to a method of preparing a fibrous protein smectic hydrogel by way of a solvent templating process, comprising the steps of pouring an aqueous fibrous protein solution into a container comprising a solvent that is not miscible with water; sealing the container and...

Control system and method for flash separation09/02/10 - 20100219127 - Provided are methods and apparatus for determining conditions for performing chromatography, particularly flash chromatography. The methods may be utilized for separating compounds in a sample in a column chromatography system. The method includes determining at least two retention factors corresponding to the TLC performance of a target compound and an...

Countercurrent tangential chromatography methods, systems, and apparatus08/05/10 - 20100193434 - This invention relates to a breakthrough in the art of chromatography allowing 1) larger scale of operation; 2) faster processing time; 3) disposability; 4) reduction of media/resin expenses; and 5) a reduction of capital equipment investment. In this invention, the chromatography column is replaced by a module that consists of...

Boron-removing agent and boron removal method utilizing xerogel04/29/10 - 20100101996 - Disclosed is a boron removal method which can remove boron from boron-containing water satisfactorily by using a small amount of a chemical agent, and which generates small amount of precipitate. Also disclosed is a boron-removing agent which is easy to handle and has excellent boron-adsorption ability. A xerogel of an...

Continuous collection method of particle component in aqueous solution and apparatus therefor04/01/10 - 20100078382 - The particle components may be collected by using a phenomenon that the particle components in the aqueous phase aggregate at the liquid-to-liquid interface. Both of the particle components and the dissolved components in the aqueous phase may be simultaneously collected if combined with liquid-liquid extraction phenomenon that the dissolved components...

Apparatus and methods for preparative liquid chromatography03/18/10 - 20100065495 - A method of liquid chromatography includes providing one or more solvent reservoirs, providing a solvent pump, drawing one or more solvents into the pump in response to a pressure drop that promotes outgassing of the solvents, and dispersing outgassed bubbles into smaller bubbles to promote re-dissolution of the gas. A...

Open-cell foam modified with hydrophobines02/25/10 - 20100044308 - Open-cell foam based on a melamine-formaldehyde condensation product, a polyurethane or a polyimide, which has been modified with hydrophobins, a method of producing such foams, and the use thereof for absorbing organic liquids, as leakage and bleeding protection for liquid stores, for liquid-liquid separation and as matrix for carrying out...

Method for purifying sialyllactose by chromatography02/18/10 - 20100038313 - The application relates to a method for purifying sialyllactose by ion-exclusion chromatography of a solution containing the sialyllactose on a mainly manovalent strong cationic resin, Na or K, and obtaining a sialyllactose-enriched raffinate....

Use of a primary liquid filtration/stabilization installation for triple purpose02/11/10 - 20100032372 - The present invention relates to a primary liquid filtration/stabilization installation comprising in combination, a liquid in-feed line, a conventional dosing tank system for single use filter-aid and/or stabilization-aid, and an alternate dosing/storage tank system for regenerable filter-aid and/or stabilization-aid, wherein the installation is adapted to selectively operate one or the...

Reaction and separation methods01/28/10 - 20100018920 - A method of separating compounds that includes the steps of: tagging at least a first organic compound with a first tagging moiety to result in a first tagged compound; tagging at least a second organic compound with a second tagging moiety different from the first tagging moiety to result in...

Method for separation01/14/10 - 20100006501 - The invention relates to a method for separation of elements from a fluid using affinity-bearing particles suspended in the fluid and using ultrasonic standing waves and micro-fluidics. The method includes the steps of: mixing said fluid mixture with particles (10) having affinity to at least one element (9) to be...

Method and device for extracting bitterness from beer12/31/09 - 20090321353 - A method for liquid-liquid extraction comprises introducing a first liquid into a container (16) and introducing a second liquid into the container (16). The second liquid is substantially immiscible with the first liquid and a one of the first and second liquid contains a substance to be extracted and the...

Method and device for desalting an analyte09/10/09 - 20090223893 - The invention provides gel filtration columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The columns typically include a bed of gel filtration media positioned above...

Modified silica gel and use thereof08/20/09 - 20090206034 - wherein each X2 is the same or different, and is a hydrogen atom, a halogen atom, or a C1-C4 alkoxy group; each R1 is the same or different and is a C1-C30alkyl group; and m is an integer from 1 to 10....

Method for selective removal of cadmium03/26/09 - 20090078649 - A method for selective removal of cadmium from a feed solution also containing other metals such as nickel (Ni) and/or cobalt (Co), utilizing a thiourea based ion exchange resin, and a method for eluting cadmium adsorbed on the thiourea based resin....

Method for separating polymer systems and pore-free polymer films used in said method02/05/09 - 20090032461 - The invention pertains to a separation of polymer systems by means of permeation through polymer films—semi-crystalline, cross-linked, amorphous—with thicknesses in a nanometer scale. The restriction to thicknesses in a nanometer scale is essential for a high throughput of polymers. Of particular significance is the selectivity towards colloidal additives with a...

Method for the extraction of components made from organic material02/05/09 - 20090032462 - The present invention relates to a process for extracting constituents from organic material, comprising the step of extracting with a monophasic mixture of 50% by volume to 90% by volume of methanol and 50 to 10% by volume of water and optionally 0% by volume to 40% by volume of...

Composite materials comprising supported porous gels02/05/09 - 20090032463 - This invention relates to a composite material that comprises a support member that has a plurality of pores extending through the support member and, located in the pores of the support member, and filling the pores of the support member, a macroporous cross-linked gel. The invention also relates to a...