In a teaser for the show that was released during the DC Universe panel at NYCC, Kaley-as-Harley addresses the crowd from Arkham Asylum, where she's locked in a cell with Poison Ivy (voiced by Lake Bell). The clip pokes fun at DC's recent "gritty" productions, as well as the failed Deadpool spin-off series, and claims that this particular project will be much lighter and more fun. The star-studded Harley Quinn cast will reportedly be rounded out by Chris Meloni, Wanda Sykes, Alan Tudyk, Jason Alexander, Natalie Morales, Diedrich Bader, and Tony Hale, among many, many others.

The show is currently in production and is set to premiere sometime in 2019. It'll be available exclusively on the DC Universe streaming service.

In an interview with EW at NYCC, Cuoco, who will soon wrap up her years-long stint on The Big Bang Theory, said she was excited to return to voice work with the new show. "[Harley Quinn] is so edgy, it's obviously a very adult comedy, and with such a world-renowned character. It's been a blast to record," she said, adding that playing the disgraced psychologist is "empowering."

"To sit in a booth and scream and cuss and yell at boys for hours at a time, it has been an absolute blast. Not having to do hair and makeup has made it that much better," she said. "But it's such an iconic character, so with all of that respect and love toward the character, we're trying to bring a new spin to it, and I think the fans that love this type of show are really going to enjoy it."

Cuoco told EW that the show will start with Harley breaking up with on-again, off-again boyfriend the Joker, and focusing instead on becoming the "best badass supervillain that there is." Along the way, she'll cross paths with DC favorites like Batman, Lex Luthor, Wonder Woman, and Doctor Psycho. "She just doesn't want to be Joker's girlfriend anymore," Cuoco said. "She wants to lead the pack, which I find very appropriate for this kind of day and age and vibe that we're in."