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Linux.com: KToon: Simple 2D Animation

"If you are running Mac OS X or Microsoft Windows, you have
access to many different animation applications, ranging from Adobe
Flash to Anime Studio. That is not so for Linux. While many think
of animation in Linux as a lost cause, there are alternatives. The
relatively new KToon calls itself 'the open source animation
revolution.' KToon has a small learning curve and an intuitive
interface, making it an excellent choice for simple animation
within Linux.

"KToon was designed for animators by the animators at Toonka. To
use KToon, you need a CPU speed of 800MHz or more, at least 256MB
of RAM, and 5MB of free space, as well as Qt 4.1.1 or higher. If
you really want to create, those numbers should probably be higher.
I have found that a processor that is faster than 1GHz with at
least 512MB of RAM does well..."