Despite the calls for Winfrey to enter the political sphere after her speech at the Golden Globes, she told the magazine she wouldn’t be able to function in a political environment, instead telling Vogue that it would kill her.

In the midst of the #MeToo movement, Winfrey also said she isn’t discouraged and has a different perspective on the state of society.

“For years, women have endured craziness,” Winfrey said in the interview. “This is what's happening to people. They're allowing themselves to not just become corroded, but to become hysterical. You've got to lean to the happiness."