As with the original Spider-Man, the filming locations are a mix of New York (where it’s set) and Los Angeles (where it’s easier to film) – and even a bit of Chicago. After the success of the first film, the budget allowed for a little more filming in the real Big Apple.

There’s Columbia University again (where Peter Parker bumps into Dr Connors), and Aunt May’s house in Woodhaven, Queens. Harry Osborn’s place is still a mix of Tudor City, Manhattan, and the Greystone Mansion, Beverly Hills (and studio sets).

After a late delivery, Parker is sacked from his job delivering pizzas for Joe’s Pizza, 233 Bleecker Street at Carmine Street in the West Village, New York.

Spider-Man 2 film location: Doc Ock's laboratory: 32 Second Avenue, East Village, New York

The laboratory, in which Dr Octavius (Alfred Molina) disastrously demonstrates his fusion project and ends up with a permanent set of tentacles, is the old Second Avenue Courthouse building, now the Anthology
Film Archive, 32 Second Avenue at Second Street in the East Village. Fittingly, it’s a centre for the preservation and exhibition of film and video.

In Los Angeles, the interior of the theatre, where Parker tries unsuccessfully to catch Mary Jane’s performance in The Importance of Being Earnest (the elaborate exterior is a set), is the somewhat plainer Ivar Theatre, 1605 North Ivar Avenue in Hollywood.

The bank robbed by Doc Ock, as Aunt May tries to get a loan, is 650 Spring Street (seen in David Fincher’s Se7en, Marathon Man and The Mask among many other films). But when Spidey rescues May from Ock’s clutches, he gently deposits her in front of City Hall, City Hall Park, Broadway at Park Row in Lower Manhattan.

The ‘New York’ el, (the elevated railway) was demolished in the 30s and 40s, so the runaway train sequence had to be filmed in Chicago, on the Chicago Loop 'L' , on Wabash Avenue between Madison and Monroe.