Topic Suggestion Description

1. Your Nomination - Please briefly describe in your own words the question about a health care test or treatment that interests or concerns you:

What is the most effective therapy for a depressed patient who has not responded to an SSRI?

2. Why do you think your question is important? (you may select more than one category if appropriate)

My question relates to a very common disease or problem

People with this disease or problem have considerable health or financial hardships

There is uncertainty about how well the test, treatment, or intervention works

There is significant potential for side effects/harms using this test, treatment, or intervention

Funding of this test, treatment, or intervention is uncertain or variable

There is unequal access or application of this health care intervention across providers

There is potential for cost savings from better information on this subject

This is a new technology/development

There is new evidence of clinical and/or cost effectiveness for this test, treatment, or intervention

Other

Other, please specify

3. What illness or health condition is related to your question? (You can also specify a particular health-promoting activity, such as breast-feeding)

Depression

4. What group(s) or patients does your question apply to?

Adults with depression.

5. What is the specific purpose of the health care test or treatment you have a question about? (mark all that you think apply)

Identification of a disease or condition:

Screening or diagnosis/identification for a particular disease, or risk assessment for a disease

Risks or harms that can come from a disease identification tool or test

Diagnostic tests and tools

Diagnosis of co-occurring diseases

Treatment of a particular disease or condition:

Intervention (such as a drug treatment, therapy, device)

Management of a condition or particular system of care

Delivery of a health service

Referral

Risks or harms associated with treatment of a disease or condition

Prevention of a particular disease or condition:

Prevention or health promotion

Specific population health concerns, such as ethnic group or gender

Other

Other

Don't know

Other, please specify:

Note:If you aren't certain about which category to select, you may select 'don't know'

6. Does your question include a comparison of different health care approaches?

Yes

No

If yes, please list what you would like to see compared:

SSRI vs other classes of antidepressants vs cognitive/behavioral therapy, or a combination of these.

7.Desired Health Improvements: If you question focuses on:

Identificationof a particular disease or condition, what improvements in identification or diagnosis would you like to see?

Treatmentof a particular disease or condition, what improvements in patient symptoms or problems would you like to see?

Improved symptoms of depression and quality of life.

8.Harms: Are there risks, side effects, or harms you are concerned about? If yes, please specify what those are:

There are potential harms to the different treatment options and there are potential harms of inadequate treatmeent.

9. Based on your answers to the previous questions, what research question(s) would you like to have answered?

How effective are diffeerent treatment options in an adult with deprression who has not responded to an SSRI?

10. Are there health-care focused, disease-focused, or patient-focused organizations that you see as being relevant to this issue? Who do you think we should contact as we consider your nomination?

American Academy of Family Physicians

11. Other Information About You (OPTIONAL)In order to help us understand the context of your health care question, it would be helpful to know more about you. The answers you give will not influence the progress of your suggestion. Thank you.

a. Please choose a description that best describes your role or perspective: (you may select more than one category if appropriate)

Administrator - hospital or other organization

Continuous quality improvement group

Health benefits plan/Insurance carrier

Health Care industry (device)

Health Care industry (drug)

Health Care industry (other)

Health Care Payer/Purchaser (employer)

Health Care Payer/Purchaser (federal government)

Health Care Payer/Purchaser (state government)

Nurse

Other

Other Health Care Professional

Patient/consumer (individual)

Patient/consumer (organization)

Pharmacist

Physician

Professional Society

Public Policymaker

Researcher

b. Is there any other information about you that is relevant to your question?

c. Are you making a suggestion as an individual or on behalf of an organization?