WELCOME TO CHATEAU DU MER BEACH RESORT

If this is your first time in my site, welcome! Chateau Du Mer is a beach resort with a beach house and conference Hall. The beach house could now accommodate 10 guests, six in the main floor and four in the first floor( air conditioned room). In addition, you can now reserve your vacation dates ahead and pay the rental fees via PayPal. I hope to see you soon in Marinduque- Home of the Morions and Heart of the Philippines. The photo above was taken during our first Garden Wedding ceremony at The Chateau Du Mer Gardens. You can now read the national and international news in this blog at the right side bar. I have also posted my favorite Filipino and American dishes and recipes in this site. Some of the photos and videos on this site, I do not own, but I have no intention on the infringement of your copyrights!

Marinduque Mainland from Tres Reyes Islands

View of Marinduque Mainland from Tres Reyes Islands-Click on photo to link to Marinduque Awaits You

Sunday, April 17, 2011

Addendum to My Article on Drug Expiration Dating and its Efficacy

The other day, I wrote my personal comments about drug expiration dating and its efficacy. I had several positive comments and it seems the topic was informative. Below is an article on the subject which added confirmation on my personal knowledge is this subject. I hope you enjoy the article as follows:

Do Medications Really Expire? By Richard Altschuler

Does the expiration date on a bottle of a medication mean anything? If a bottle of Tylenol, for example, says something like "Do not use after June 1998," and it is August 2002, should you take the Tylenol? Should you discard it? Can you get hurt if you take it? Will it simply have lost its potency and do you no good?

In other words, are drug manufacturers being honest with us when they put an expiration date on their medications, or is the practice of dating just another drug industry scam, to get us to buy new medications when the old ones that purportedly have "expired" are still perfectly good?

These are the pressing questions I investigated after my mother-in-law recently said to me, "It doesn't mean anything," when I pointed out that the Tylenol she was about to take had "expired" 4 years and a few months ago. I was a bit mocking in my pronouncement -- feeling superior that I had noticed the chemical corpse in her cabinet -- but she was equally adamant in her reply, and is generally very sage about medical issues.

So I gave her a glass of water with the purportedly "dead" drug, of which she took 2 capsules for a pain in the upper back. About a half hour later she reported the pain seemed to have eased up a bit. I said "You could be having a placebo effect," not wanting to simply concede she was right about the drug, and also not actually knowing what I was talking about. I was just happy to hear that her pain had eased, even before we had our evening cocktails and hot tub dip (we were in "Leisure World," near Laguna Beach, California, where the hot tub is bigger than most Manhattan apartments, and "Heaven," as generally portrayed, would be raucous by comparison).

Upon my return to NYC and high-speed connection, I immediately scoured the medical databases and general literature for the answer to my question about drug expiration labeling. And voila, no sooner than I could say "Screwed again by the pharmaceutical industry," I had my answer. Here are the simple facts:

First, the expiration date, required by law in the United States, beginning in 1979, specifies only the date the manufacturer guarantees the full potency and safety of the drug -- it does not mean how long the drug is actually "good" or safe to use.

Second, medical authorities uniformly say it is safe to take drugs past their expiration date -- no matter how "expired" the drugs purportedly are. Except for possibly the rarest of exceptions, you won't get hurt and you certainly won't get killed.

Studies show that expired drugs may lose some of their potency over time, from as little as 5% or less to 50% or more (though usually much less than the latter). Even 10 years after the "expiration date," most drugs have a good deal of their original potency. So wisdom dictates that if your life does depend on an expired drug, and you must have 100% or so of its original strength, you should probably toss it and get a refill, " If your life does not depend on an expired drug -- such as that for headache, hay fever, or menstrual cramps -- take it and see what happens.

One of the largest studies ever conducted that supports the above points about "expired drug" labeling was done by the US military 15 years ago, according to a feature story in the Wall Street Journal (March 29, 2000), reported by Laurie P. Cohen. The military was sitting on a $1 billion stockpile of drugs and facing the daunting process of destroying and replacing its supply every 2 to 3 years, so it began a testing program to see if it could extend the life of its inventory. The testing, conducted by the US Food and Drug Administration (FDA), ultimately covered more than 100 drugs, prescription and over-the-counter. The results showed that about 90% of them were safe and effective as far as 15 years past their original expiration date. ( I have personal knowledge of this having worked for FDA for 12 years)

In light of these results, a former director of the testing program, Francis Flaherty, said he concluded that expiration dates put on by manufacturers typically have no bearing on whether a drug is usable for longer. Mr. Flaherty noted that a drug maker is required to prove only that a drug is still good on whatever expiration date the company chooses to set. The expiration date doesn't mean, or even suggest, that the drug will stop being effective after that, nor that it will become harmful. "Manufacturers put expiration dates on for marketing, rather than scientific, reasons," said Mr. Flaherty, a pharmacist at the FDA until his retirement in 1999. "It's not profitable for them to have products on a shelf for 10 years. They want turnover."

The FDA cautioned there isn't enough evidence from the program, which is weighted toward drugs used during combat, to conclude most drugs in consumers' medicine cabinets are potent beyond the expiration date. Joel Davis, however, a former FDA expiration-date compliance chief, said that with a handful of exceptions -- notably nitroglycerin, insulin, and some liquid antibiotics -- most drugs are probably as durable as those the agency has tested for the military. "Most drugs degrade very slowly," he said. "In all likelihood, you can take a product you have at home and keep it for many years." Consider aspirin. Bayer AG puts 2-year or 3-year dates on aspirin and says that it should be discarded after that. However, Chris Allen, a vice president at the Bayer unit that makes aspirin, said the dating is "pretty conservative"; when Bayer has tested 4-year-old aspirin, it remained 100% effective, he said. So why doesn't Bayer set a 4-year expiration date? Because the company often changes packaging, and it undertakes "continuous improvement programs," Mr. Allen said. Each change triggers a need for more expiration-date testing, and testing each time for a 4-year life would be impractical. Bayer has never tested aspirin beyond 4 years, Mr. Allen said. But Jens Carstensen has. Dr. Carstensen, professor emeritus at the University of Wisconsin's pharmacy school, who wrote what is considered the main text on drug stability, said, "I did a study of different aspirins, and after 5 years, Bayer was still excellent. Aspirin, if made correctly, is very stable.

Now I think I'll take a swig of the 10-year dead package of Alka Seltzer in my medicine chest -- to ease the nausea I'm feeling from calculating how many billions of dollars the pharmaceutical industry bilks out of unknowing consumers every year who discard perfectly good drugs and buy new ones because they trust the industry's "expiration date labeling."

Again, do you find this article informative? Cheers to ALL! Happy Easter!

Feedjit

Travel Site Catalog

ABOUT ME

I am a retired (Chemistry Team Leader from USFDA) Filipino-American who loves writing, gardening and photography. My wife (of 58 years) and I enjoy our snowbird lifestyle between the US and the Philippines. We have a small but very private beach resort (above video) in the beautiful island of Marinduque, Philippines. I have several blog sites(ten), a personal blog, blogs about Marinduque and our beach resort and conference center-CHATEAU DU MER. I also write for www.squidoo.com now owned by Hubpages.com

Sunset from CDM Beach Resort

Click on Photo to link to Marinduque Blog

Recent Photos of Orchids in the Gardens of Chateau Du Mer

A dark Yellow Vanda
A dark pink Vanda
A Small light yellow Phaelonopsis
A reddish Vanda
A pinkish-white Vanda
Another favorite Vanda
My twin blue Princess Mikasa
One of My Favorite Vanda
The above photos are some of the orchids blooming in the gardens of Chateau Du Mer from January to April, 2011. I hope you like them as much as I do! I have a dozen more plants that are blooming, but it will just be too boring to publish them all in this blog. Your comments will be appreciated.

Chateau Du Mer Beach Resort

Beach House, Boac, Marinduque, Philippines

Blue Orchid - Chateau Du Mer

Princess Mikasa-My Favorite Variety

Chateau Du Mer Beach Resort Logo

Chateau Du Mer Logo-Click Photo to link to Life in US

Chateau Du Mer Beach Resort

Beach House and Bridge

Chateau Du Mer Beach Resort and Conference Center

Conference Center and Multi-Purpose Hall

Chateau Du Mer Beach Resort

Beach House Balcony at Night

BlogCatalog

Coral Reefs of Amoingon Coast

Click Photo for Link/Details

Disclaimer: Most of the photos and videos included in this blog are not owned by me unless stated. If you are the owner of the photo/video and you would like to be credited, please let me know and I will pay proper attribution after careful verification of your identity and of your 'claimed' image/s. The photos/videos used in this blog are results of myGoogle and other Internet searches. Thank you and if you enjoy this blog, help support it by clicking on the ads.

Orchid in Front of Main House-Chateau Du Mer-click on photo to link to Marinduque Awaits You