Dosage

Higher daily doses of rifampin, a cornerstone of tuberculosis treatment, were shown to kill more TB bacteria in sputum cultures without increasing the adverse effects of treatment, according to a recent randomised controlled trial.

Better timing for cortisol replacement therapies, to more closely replicate the secretion patterns of people with normal levels of the hormone, has shown a significant improvement in patients' cognitive function...

Researchers in the US have found that a common practice among physicians to increase the use of steroids for worsening symptoms of asthma in children may be associated with slowing a child’s rate of growth.

Designing appropriate non-clinical safety studies requires thoughtful, and sometimes experimental, consideration of the delivery methodology for the therapeutic. The choice of formulation affects drug release and absorption and has a direct impact on the pharmacokinetic profile and associated response of the model system. The formulation should be compatible with the…