Re: Metabolizing/Restarting

I'm one of those slow metabolizers--I used to take prozac for a few days and be covered for a month. Tiny bits of some drugs do it for me when standard doses just make me feel bad. (Not so others. Immediate action meds seem to be different.)

I'm on day 3 of Strattera for the second time around. Gave up the first time because I couldn't sort out the Strattera effects from stimulant withdrawal. I feel alternately sedated and then energetic and nicely focused...possibly at onset it sedates me and then the more positive effect kicks in (including appetite supression). Sleep is definitely weird, though.

Maybe the reason some people feel an almost immediate response is something like what commonly happens with Lamictal—an initial improvement after a few days which levels off or decreases but kicks back in when the theraputic dose is reached.