Lyle Overbay hit a tiebreaking, two-run double in the ninth inning off Edward Mujica, and the Milwaukee Brewers beat the Red Sox 6-2 Friday in Boston's first game at Fenway since winning the World Series last October.

"They came out swinging against Mujica," Red Sox manager John Farrell said. "Knowing he's been in the National League Central, they're familiar with him. At the same time, Edward's had a lot of success against that lineup. He mislocated a couple of balls, and he paid for it."

Boston's streak in home openers was tied with Cincinnati (1983-91) for the third-longest in major league history, ending behind 11 straight by the New York Yankees (1998-08) and 10 by Pittsburgh (1945-54).

Khris Davis doubled off Mujica (0-1), who made his Boston debut, and took third when Scooter Gennett reached on a sacrifice bunt. Overbay doubled to right for a 4-2 lead, advanced on the throw and scored on Carlos Gomez's fourth single of the game. Aramis Ramirez added an RBI single.

Ryan Braun was 0 for 5 and was booed each time he came to the plate in his first road game following his 65-game suspension last season. Four days earlier, home fans applauded the 2011 NL MVP loudly during Milwaukee's season opener.

Mujica was the St. Louis Cardinals' closer for much of last season, then lost that job last September and did not pitch in the World Series. He signed a $9.75 million, two-year deal with Boston.

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