Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )

Length:

67

Sequences:

481

Seq/Len:

7.18

HH_delta:

0.866 (20Jul13)

GREMLIN Results:
Residue pairs sorted by strength in covariance:Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

i

j

Raw Score

Scaled Score

8_N

12_W

0.39837

2.618

2_V

10_Y

0.34468

2.265

39_G

42_I

0.2744

1.803

6_K

28_D

0.25234

1.658

24_H

28_D

0.25062

1.647

17_V

44_L

0.23499

1.544

55_F

58_R

0.23297

1.531

3_T

13_Y

0.21881

1.438

5_N

9_T

0.21763

1.430

18_Y

41_K

0.21075

1.385

18_Y

44_L

0.20662

1.358

5_N

8_N

0.19664

1.292

29_R

33_M

0.18924

1.244

18_Y

43_P

0.18132

1.192

5_N

13_Y

0.17796

1.170

6_K

10_Y

0.17378

1.142

16_R

42_I

0.17195

1.130

53_P

58_R

0.17094

1.123

3_T

11_D

0.1706

1.121

19_K

44_L

0.16583

1.090

13_Y

16_R

0.16459

1.082

20_L

24_H

0.16374

1.076

28_D

32_A

0.16353

1.075

4_F

14_K

0.15835

1.041

20_L

47_F

0.15722

1.033

2_V

13_Y

0.15648

1.028

10_Y

28_D

0.15585

1.024

2_V

9_T

0.15375

1.010

11_D

50_N

0.14751

0.969

43_P

46_I

0.14731

0.968

11_D

15_E

0.14715

0.967

27_S

49_R

0.14663

0.964

9_T

13_Y

0.14624

0.961

12_W

26_P

0.14577

0.958

26_P

29_R

0.14375

0.945

55_F

59_L

0.14366

0.944

41_K

51_E

0.1422

0.935

14_K

34_E

0.14177

0.932

41_K

47_F

0.14108

0.927

34_E

61_E

0.14055

0.924

49_R

52_R

0.14012

0.921

16_R

39_G

0.13939

0.916

32_A

48_Y

0.13859

0.911

25_D

28_D

0.13626

0.895

29_R

44_L

0.13319

0.875

15_E

56_E

0.13254

0.871

49_R

53_P

0.13192

0.867

1_C

56_E

0.13121

0.862

17_V

62_L

0.13072

0.859

58_R

61_E

0.12994

0.854

2_V

22_E

0.1296

0.852

39_G

43_P

0.12769

0.839

27_S

33_M

0.12592

0.828

2_V

15_E

0.12574

0.826

46_I

49_R

0.12492

0.821

54_T

57_E

0.12419

0.816

11_D

21_D

0.12384

0.814

50_N

62_L

0.12341

0.811

34_E

41_K

0.12311

0.809

9_T

12_W

0.12214

0.803

11_D

51_E

0.12171

0.800

21_D

57_E

0.12136

0.798

26_P

53_P

0.12126

0.797

21_D

53_P

0.12122

0.797

24_H

47_F

0.12046

0.792

58_R

62_L

0.12003

0.789

16_R

60_P

0.11999

0.789

12_W

42_I

0.11913

0.783

13_Y

51_E

0.11691

0.768

21_D

48_Y

0.11623

0.764

22_E

58_R

0.11492

0.755

14_K

29_R

0.11416

0.750

17_V

48_Y

0.1138

0.748

24_H

29_R

0.11259

0.740

7_I

12_W

0.11096

0.729

22_E

40_D

0.1109

0.729

11_D

47_F

0.11046

0.726

5_N

24_H

0.10939

0.719

17_V

57_E

0.1087

0.714

29_R

52_R

0.10779

0.708

18_Y

22_E

0.10733

0.705

29_R

56_E

0.10703

0.703

7_I

33_M

0.10682

0.702

29_R

46_I

0.10667

0.701

Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.