Hi Till:
Any change triggers an update to all users? For example: the change of the password?
I ask because i have many users and that is time-consuming task, each time a user changes his password, the change is not instantaneous. The delay of actions is 5 to 10 minutes.

Any change triggers an update to all users? For example: the change of the password?

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Yes. Typical sites have 5 - 10 users, so this does not matter. If your server has hunbdreds of users in one site, you should consider to migrate to use ISPConfig 3 when it becomes stable as iSPConfig 3 does not use Linux system users for email.