Browsing Physiology and biophysics by Subject "Physiology and biophysics"

Proteolytic cleavage of amyloid precursor protein (APP) generates the amyloid β peptide (Aβ), the main component of cortical and subcortical plaques in Alzheimer's disease (AD). APP can be processed at the cell surface or ...

Muscle is highly organized in both the axial direction and the radial direction, or the direction of contraction and the direction orthogonal to it. As muscle generates force, it does so in both the axial and radial ...

Before physically dividing into two nascent daughter cells, a cell must first duplicate, organize and segregate its entire genome. During mitosis, chromosomes are aligned along an axis of symmetry and then pulled apart by ...

L-type Ca<super>2+</super> (Ca<sub>V</sub>1.2) channels shape the cardiac action potential waveform and are essential for excitation-contraction (EC) coupling in the heart. We find that a transient subpopulation of 2 to ...