Method for the Measurement of 14C-5 HT Uptake and Release by Platelets

Abstract

It has long been known that platelets take up and store 5—hydroxytryptamine (5-HT); under certain conditions, they can also release it. The affinity of platelets for this biogenic amine and its role in platelet aggregation are factors which could influence the formation of hemostatic platelet plug and thrombus.(1–7)