At the beginning of Part 5, Colton is sent to alert the president of the arrival of Chew Toy, the helicopter piloted by Jeff and containing the rest of the group. When they are cleared, Colton runs back off to deliver the confirmation.

When Brian's group was detained, they were immediately screened and quarantined. Later, when Jack is found to be the former Alpha, President Craig Fitzpatrick took Colton's pistol and prepared to shoot Jack. Brian escaped his restraints and tried to help his dad, so Craig ordered Colton to grab the boy. When he did, however, Brian thrashed around and accidentally bit the soldier on the hand. Pvt. Mulroney dropped Brian and fell to the ground, starting to transform. Before he could, Craig shot him in the back of the head. By doing so, some of Colton's infected blood splashed into Craig's eyes, infecting him and ultimately leading to the deaths of several people.