A Developmental Process Independent of Morphogenetic (shape) Change That Is Required For an Oocyte to Attain Its Fully Functional State. Oocyte Maturation Commences After Reinitiation of Meiosis Commonly Starting with Germinal Vesicle Breakdown and Continues Up to the Second Meiotic Arrest Prior to Fertilization.

Any Process That Results in a Change in State or Activity of a Cell or an Organism (in Terms of Movement Secretion Enzyme Production Gene Expression Etc.) As a Result of a Stimulus Indicating Lowered Oxygen Tension. Hypoxia Defined As a Decline in O2 Levels Below Normoxic Levels of 20.8 20.95% Results in Metabolic Adaptation At Both the Cellular and Organismal Level.

The Process Whose Specific Outcome Is the Progression of the Placenta Over Time From Its Formation to the Mature Structure. the Placenta Is an Organ of Metabolic Interchange Between Fetus and Mother Partly of Embryonic Origin and Partly of Maternal Origin.

The Chemical Reactions and Pathways Resulting in the Formation of Diacylglycerol a Glyceride in Which Any Two of the R Groups (positions Not Specified) Are Acyl Groups While the Remaining R Group Can Be Either H or an Alkyl Group.

Any Process That Mediates Interactions Between a Cell and Its Surroundings. Encompasses Interactions Such As Signaling or Attachment Between One Cell and Another Cell Between a Cell and an Extracellular Matrix or Between a Cell and Any Other Aspect of Its Environment.

The Initiation of the Activity of the Inactive Enzyme Phospolipase C As the Result of a Series of Molecular Signals Generated As a Consequence of a G Protein Coupled Receptor Binding to Its Physiological Ligand.

The Biological Process Whose Specific Outcome Is the Progression of a Multicellular Organism Over Time From an Initial Condition (e.g. a Zygote or a Young Adult) to a Later Condition (e.g. a Multicellular Animal or an Aged Adult).

The Controlled Self Propelled Movement of a Cell From One Site to a Destination Guided by Molecular Cues. Cell Migration Is a Central Process in the Development and Maintenance of Multicellular Organisms.

The Process in Which Relatively Unspecialized Cells E.g. Embryonic or Regenerative Cells Acquire Specialized Structural And/or Functional Features That Characterize the Cells Tissues or Organs of the Mature Organism or Some Other Relatively Stable Phase of the Organism's Life History. Differentiation Includes the Processes Involved in Commitment of a Cell to a Specific Fate and Its Subsequent Development to the Mature State.

The Space External to the Outermost Structure of a Cell. For Cells Without External Protective or External Encapsulating Structures This Refers to Space Outside of the Plasma Membrane. This Term Covers the Host Cell Environment Outside an Intracellular Parasite.

A Layer Consisting Mainly of Proteins (especially Collagen) and Glycosaminoglycans (mostly As Proteoglycans) That Forms a Sheet Underlying or Overlying Cells Such As Endothelial and Epithelial Cells. the Proteins Are Secreted by Cells in the Vicinity. an Example of This Component Is Found in Mus Musculus.

A Thin Layer of Dense Material Found in Various Animal Tissues Interposed Between the Cells and the Adjacent Connective Tissue. It Consists of the Basal Lamina Plus an Associated Layer of Reticulin Fibers.

A Membrane Bounded Organelle of Eukaryotic Cells in Which Chromosomes Are Housed and Replicated. in Most Cells the Nucleus Contains All of the Cell's Chromosomes Except the Organellar Chromosomes and Is the Site of RNA Synthesis and Processing. in Some Species or in Specialized Cell Types RNA Metabolism or DNA Replication May Be Absent.

A Small Dense Body One or More of Which Are Present in the Nucleus of Eukaryotic Cells. It Is Rich in RNA and Protein Is Not Bounded by a Limiting Membrane and Is Not Seen During Mitosis. Its Prime Function Is the Transcription of the Nucleolar DNA Into 45s Ribosomal Precursor RNA the Processing of This RNA Into 5.8s 18s and 28s Components of Ribosomal RNA and the Association of These Components with 5s RNA and Proteins Synthesized Outside the Nucleolus. This Association Results in the Formation of Ribonucleoprotein Precursors; These Pass Into the Cytoplasm and Mature Into the 40s and 60s Subunits of the Ribosome.

A Membrane Bounded Vesicle That Is Released Into the Extracellular Region by Fusion of the Limiting Endosomal Membrane of a Multivesicular Body with the Plasma Membrane. Extracellular Exosomes Also Simply Called Exosomes Have a Diameter of About 40 100 Nm.

Interacting Selectively and Non Covalently with One or More Specific Sites On a Receptor Molecule a Macromolecule That Undergoes Combination with a Hormone Neurotransmitter Drug or Intracellular Messenger to Initiate a Change in Cell Function.

Interacting Selectively and Non Covalently with Heparin Any Member of a Group of Glycosaminoglycans Found Mainly As an Intracellular Component of Mast Cells and Which Consist Predominantly of Alternating Alpha (1 >4) Linked D Galactose and N Acetyl D Glucosamine 6 Sulfate Residues.