From experience, acne gets much worse the longer a cycle gets, and then the HUGE breakout in PCTAnd hairloss comes from hair follicules gradually shrinking and eventually dying and falling out from continuous strong androgen exposure

So.. if I do 2 on and 1 off

1) My sebacious glands won't be so active and there won't be as much of an HPTA shutdown, so acne and PCT acne won't be as harsh

2) I won't be under continuous heavy androgens so hair follicules won't have a chance to die and fall of

This is how I'm imagining it.Opinions?

PS:

For extra acne protection I'll be running 40mg of Accutane and 100mg of Doxy EDFor hair protection I'll be running .5mg of fina ED and I'm gonna get some Nizoral shampoo

Don't use accutane and an antibiotic at the same time. If you run either be careful with your liver. No oral steroids or rec drugs. 2 on 1 off might be better for sides, but it's a moot point. If you have the MPB gene, you're going to lose your hair no matter what.

In my opinion you should just deal with it and run a regular 12 week cycle. Are you sure you have the MPB gene? I understand your rational about the hair follicles, and it does make sense, but I don't know if hair follicles are logical. What is true is that if you take any steroids, your hair will fall out more quickly than it would without steroid usage.

Counterpoint: Bill Roberts suggests 2 on 2 off with deca for female body builders. Articles about women & steroids are good reads.

I think there's a higher chance of all the ancillary drugs causing issues, than there is of the ancillaries solving issues.

I'm also going to die someday, I'd rather put it off as long as possible.

Exactly. I don't get the "who cares, just shave your head" crowd. If we can delay it as much as possible, why not? Since using Nioxin shampoo I've not lost any significant hair in years.

As for acne, I got my first outburst after going OFF. Since then, I get about one pimple a week whatever I do (back, shoulder, belly, even legs sometimes). Sucks but not horrible. I never had any acne issues as a teenager, and certainly not in those weird places. But, being on, off, whatever, doesn't change a things for me. So I wouldn't do your 2 on 1 off thing, but that's just me.

For the same number of weeks "on" per year and same choice and amount of total drug use, with regard to hair loss or acne I don't think short cycles have any advantage over longer cycles.

On the acne, your principal culprit may be the SERM used in PCT.

Where hypothetically short cycles could give an advantage is that it could be a reasonable plan to only use an AI as PCT when the cycle length is only 2 weeks, as recovery is so easy. E.g., letrozole at 1 mg on day 1, and about 0.36 mg/day after that for 2 weeks.

I'm talking about an androgen that doesn't automatize to DHT or estrogen. There are two distinct androgen receptors, not one, so that complicates things. It's also irrelevant to this issue. Let's pretend there's only one type of androgen receptor. For example, you can think of it as insulin. There's really only one type of insulin, and one type of insulin receptor.

I guess the idea you're talking about (which I think I've heard somewhere before) is that muscle cells will react differently tothe amount of androgens than hair follicle cells will. I don't know of any reason why one type of tissue will react differently to length of time exposed to androgens, or total amount, etc.

I don't know if I'm making sense. Basically, the entire idea is that a hair follicle cell will react differently to the length of time exposed to an androgen than a muscle cell will. I don't see why a pulse of androgens will make muscle cells grow, but not make hair fall out. There's no scientific reason to support this idea. If a higher dose for a shorter period of time has less of an effect on hair cells, it will also have less of an effect on muscle cells.

I have heard that women are supposed to pulse steroids in 2-3 week intervals to avoid virilization. Sorry, Bill Roberts, I'm not sure if I actually read that in one of your articles. It might have been that shithead Anthony Roberts. Either way, no universities are doing research into BodyBuilder Steroid enhancers, so this all just my opinion.

'I don't know if I'm making sense. Basically, the entire idea is that a hair follicle cell will react differently to the length of time exposed to an androgen than a muscle cell will. I don't see why a pulse of androgens will make muscle cells grow, but not make hair fall out.'

Hair follicules gradually shrink before they die and fall off.It's why plenty of users experience thinning on cycle but it bounces back when they're off, the follicule didn't effectively die.