Dozens of people have been hurt. They were taken to area hospitals where 10 people remained hospitalized Wednesday evening, according to a Greyhound spokesman.

Trooper Matthew Burrows said the bus struck the rear end of a flatbed trailer that was hauling bales of garbage. He said the bus was extensively damaged.

The driver of the bus has been identified by Pennsylvania State Police as Sabrina Anderson, 42, of Cleveland.

At least two other Clevelanders were passengers on the bus -- Manaja Livinston, 21, and Shara King, 37. A passenger list sent out by the State Police did not list a city or state for many of the passengers on the bus, however.

Alexandra Pedrini, Greyhound spokeswoman, said most of the 50 people on board were taken to five local hospitals. Those hospitals are: Evangelical Medical Center, Geisinger Medical Center, Williamsport Regional Hospital, Lockhaven Hospital and Muncie Valley Hospital.

Pedrini said the bus driver has been with the company for more than 12 years. The driver is on administrative leave until the crash investigation is completed. Pedrini says the move is standard operating procedure.

Those passengers not hurt in the crash and those treated and released from the hospital have been placed on other buses to continue their trip to Cleveland.

Greyhound Lines are asking for anyone who believes their family members may have been involved in the crash should contact them at 1-800-972-4583.