Summary:
The DinF protein is an uncharacterised member of the MATE family of multidrug efflux transporters [Brown99a]. Expression of the dinF gene is DNA damage (UV or mitomycin C) inducible [Kenyon80]. The dinF gene is located downstream of the lexA gene, which encodes the global repressor of the SOS regulon. Based on sequence similarity, DinF may function as a proton-driven efflux system, possibly for nucleotides given its potential role in response to DNA damage.