150 West Jefferson is a skyscraper and class-A office center in DowntownDetroit, Michigan. The building's construction began in 1987 and was completed in 1989. It stands at 26 stories tall, with two basement floors, for a total of 28. The building stands at 150 West Jefferson Avenue, between Shelby Street and Griswold Street, and between Jefferson and Larned Street bordering the Detroit Financial District.

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The building's main exterior materials include glass, granite, and concrete in a postmodern architectural design. The high-rise building is primarily used as an Office tower, with a parking garage, restaurant and retail offices inside it. This building is connected to the rest of downtown Detroit by a station stop on the Detroit People Mover transit system built into the adjacent parking ramp. The 150 West Jefferson high rise replaced the Detroit Stock Exchange Building. Some of the façade of the old building was preserved and incorporated into the interior and exterior decoration of the new building. The skyscraper rises 444' 6" from its front entrance off West Jefferson Avenue. The back entrance off the podium on Larned Street actually sits 7' lower. Four flagpoles, each 30 feet (9 m) high, are located at each corner of the top of the slanted roof. Each displays an American flag; the four can be seen across the river in Windsor, Ontario.