methotrexate sodium oral and phenytoin sodium extended oral

methotrexate sodium oral increases toxicity of phenytoin sodium extended oral by Other (see comment). Methotrexate is partially bound to serum albumin, and toxicity may be increased because of displacement by certain drugs, such as phenytoin.

phenytoin sodium extended oral and methotrexate sodium oral

phenytoin sodium extended oral increases toxicity of methotrexate sodium oral by Other (see comment). Methotrexate is partially bound to serum albumin, and toxicity may be increased because of displacement by certain drugs, such as phenytoin.

Significant

Minor

Interaction is unlikely, minor, or nonsignificant

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