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Usages:

This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Exemestane is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen.Exemestane decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.

Mechanism Of Action:

Exemestane is an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate androstenedione. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme, causing its inactivation, an effect also known as "suicide inhibition."

Exemestane significantly lowers circulating estrogen concentrations in postmenopausal women, but has no detectable effect on adrenal biosynthesis of corticosteroids or aldosterone. Exemestane has no effect on other enzymes involved in the steroidogenic pathway up to a concentration at least 600 times higher than that inhibiting the aromatase enzyme.

Breast Cancer that has Spread to Another Part of the Body Medications;Prevention of Breast Cancer Medications;Advanced Breast Cancer Progression Post-Antiestrogen Therapy Medications

How to use exemestane?

Take this medication by mouth, usually once daily with food (after a meal), or as directed by your doctor.

Dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

We do understand that you will be worried about our packing methods before you tried or knew us, while we are making the real deal and we do know how customs works. We have professionfal team for special disguised package, no word concern steroid will be whown on the parcels, the pass custom rate is more than 99%.Before we could be able to offer some details of our package and shipping methods, and it is better to discuss by mail , skype.Our company owns a professional and efficient team for packing with our best discrete or stealth packages. Orders will be sent out within only one working day after payment.Package details and tracking number will be ent to you.Shipment by DHL, TNT, FedEx, HKEMS, UPS, ,EUB,ETK and so on.It usually takes 4 to 7 days or 7 to 10 days by some other express courier; it will be 15 to 20 days by slowpost.

Our company owns a professional and efficient team for packing with our best discrete or stealth packages. Orders will be sent out within only one working day after payment.Package details and tracking number will be ent to you.Shipment by DHL, TNT, FedEx, HKEMS, UPS, ,EUB,ETK and so on.It usually takes 4 to 7 days or 7 to 10 days by some other express courier; it will be 15 to 20 days by slowpost.

Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month. We will stack on the parcels until you get them on hand so that you do not need to spare time on this.