Press Release

NeoChord Passes 500 Patient Treatment Milestone

NeoChord, Inc., a privately-held global medical technology company,
today announced that it has surpassed the 500 patient treatment
threshold for its DS1000 Artificial Chordae Delivery System.

With traditional open mitral repair procedures, the heart is stopped,
and the patient is placed on cardiopulmonary bypass. With the NeoChord
System, the mitral valve is repaired while the heart is beating, and a
real-time assessment of the correction of mitral regurgitation is
performed.

“Achievement of a 500+ patient treatment milestone affirms the adoption
of this new procedure in Europe. The excellent two-year outcomes from
the University of Padua may be an early confirmatory signal for the long
term durability of our procedure and confirms the promise that this
technology holds for patients suffering from degenerative mitral valve
disease. We believe these impressive results will also be observed in
the U.S. pivotal trial, which will commence this year,” said David
Chung, CEO and President, NeoChord.

New data from the University of Padua demonstrated that patients had
improved ventricular function, no increase in mitral annular dimension,
and no recurrence or worsening of mitral regurgitation at up to two
years after treatment with the NeoChord DS1000 System and was presented
at the annual meeting of the European Association for Cardio-Thoracic
Surgery (EACTS) in Barcelona.

“We are very pleased with the mid-term clinical outcomes observed in our
series of patients with prolapsed and flail leaflets,” stated Professor
Gino Gerosa MD, PhD, Chief of Cardiac Surgery, Department of Cardiac,
Thoracic, and Vascular Sciences, University of Padua, Italy. “The
one-year results in our series has been previously reported, so it is
extremely promising to observe that these results have been sustained in
our patients out to two years,” stated Gerosa. “While we will continue
to study these patents, these data suggest that concomitant annuloplasty
may not be mandatory in the treatment of degenerative mitral valve
regurgitation.”

Dr. Andrea Colli, MD, PhD, FECTS, Department of Cardiac, Thoracic, and
Vascular Sciences, University of Padua, Italy, reported on the two-year
outcomes of 127 patients that received echo-guided transapical, off-pump
mitral valve repair with artificial chordae Implantation with the
NeoChord Artificial Chordae Delivery System, Model DS1000. “In our
series, we observed improvement in left ventricular function, (p=0.001),
and no increase in mitral annular dimension, (p=0.862)
between the follow-up periods of discharge and two-years,” said Colli.
“These data are remarkable because they are consistent with results that
have been reported and are expected in open mitral repair procedures.”

About NeoChord, Inc.Based in St. Louis Park, Minn.,
NeoChord, Inc. is a privately held medical technology company leading
the advancement of minimally invasive repair for degenerative mitral
regurgitation (DMR). DMR is a progressive disease that can result in
atrial fibrillation, congestive heart failure, and death when left
untreated. NeoChord received CE market clearance in December 2012 for
the DS1000 System to treat DMR without the use of cardiopulmonary
bypass. NeoChord received IDE approval from the FDA to begin the US
pivotal trial in May 2016. For more information, visit: www.NeoChord.com.

The NeoChord DS1000 System is CE marked and approved for sale in
Europe.

CAUTION: Investigational Device Limited by Federal (United States)
Law to Investigational Use

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