With the onset of the Flood and the Refugee Crisis, a number of countries entered into civil war as now geographically isolated regions rebelled against the governing bodies that they felt had abandoned them. Save for the Chinese Civil War, no country was more badly effected than Russia.

The Russian Civil war was the culmination of decades of political turmoil and civil unrest that was amplified by the Flood. Now isolated regions and ethnic groups began waging much more successful defensive wars of secession. While the Caucasus and the Sapmi regions were the first to break away, what drove the majority of the Russian Federation's attention in the war was the secession of Siberia under the leadership of the Siberian Liberation Army, and their allies in Western Russia under the leadership of the National Bolshevic Party.

The civil war in Russia lasted five years, and ultimately came to an end with the detonation of several captured Vacuum bombs against key Russian naval and air bases by the Red Siberians. The war concluded with the collapse of the Russian Federation, and creation of the Siberian Socialist Republic, among other post-Russian nations.