Generic ( Epirubicin )

Epirubicin Has Antimitotic And Cytotoxic Activity. It Inhibits Nucleic Acid (DNA And RNA) And Protein Synthesis Through A Number Of Proposed Mechanisms Of Action: Epirubicin Forms Complexes With DNA By Intercalation Between Base Pairs, And It Inhibits Topoisomerase II Activity By Stabilizing The DNA-topoisomerase II Complex, Preventing The Religation Portion Of The Ligation-religation Reaction That Topoisomerase II Catalyzes. It Also Interferes With DNA Replication And Transcription By Inhibiting DNA Helicase Activity.