As noted on the Bethesda Blog, the first patch for Fallout: New Vegas is now available automatically through Steam, where word is: "This update fixes quest and scripting issues." They say they are working on getting the console versions of Obsidian's RPG sequel patched as soon as possible, and also announce that the issue with PlayStation 3 digital preorder bonuses is now resolved.

Eldaron Imotholin wrote on Oct 21, 2010, 05:57:The sensitivity seems to... fluctuate? It's like I have some sort of "smooth mouse" option enabled or whatever. It's damn annoying. Anyone know what I'm talking about? Maybe it's because I have Vsync enabled? There's also this minor weirdness with my character sometimes taking another step before stopping, while I had already lifted my finger from the keyboard. Often when I'm stopping while making a curve.

There's a disconnect between the mouse sensitivity in the menu and in the game. So its not very sensitive in the game, but then when you open inventory for instance its extra sensitive. FO3 was like that too.

If I had to guess, I'd guess that the windows sensitivity is taking over in menus, while the game sensitivity is taking over while doing the game parts. Try turning down windows sensitivity, see if that helps.