Content

You will carry out case studies selected to illustrate the multifactorial and integrated nature of disease and its laboratory investigation. Indicative content includes:

Homeostasis and malignant disease: Central importance of homeostasis, mechanisms of control and the consequences of failure. Concepts of disease and normality, reference ranges Mechanisms of cancer development at a cellular level, haematological disorders and diagnosis and treatment.

Cellular Pathology: Microscopic analysis of cells and tissues. Preparative processes for microscopical analysis of tissues and cells. Cell and tissue stabilisation. Histological and cytological features of the disease state. Clinical laboratory applications of cellular pathology; its role in diagnosis, prognosis and prediction.

Clinical Biochemistry: diagnosis, screening and monitoring of disease through qualitative and quantitative evaluation. Diagnosis of Liver, Cardiac diseases and endocrine disorders. Drug toxicity and drug monitoring Haematology and Transfusion Science: haematology of normal and disease states, haemoglobinopathies and thalassaemias, anaemias, leukaemias and thrombosis. Laboratory investigation of disease states. The role of the laboratory in monitoring of therapy. Immunohaematology; including identification of blood group antigens, methods for antibody detection and compatibility testing and safety aspects of blood transfusion.