When Clyde's mother dies after falling in the toilet (due to Clyde leaving the toilet seat up), the government hires TSA agents to patrol anyone and everyone who goes to the bathroom with a belt attached to the toilet. Meanwhile, Stan convinces Clyde to sue the inventor of the toilet, so he employs a lawyer who conducts a séance that will allow this to happen.

Stan discovers the horrible secret behind home-shopping networks that sell cheap jewelry to the elderly after trying to sell a bolo tie that his grandfather gave him as a birthday present. Meanwhile, Cartman starts a cash-for-gold scam.

The boys get into meme photography, become discouraged and conflicted after learning that the meme that they tried to perform at the Republican National Convention has been supplanted in popularity by newer ones, including one that leads investigators to believe that cats are evolving in intelligence, and have become a threat to humanity.

When a new black girl named Nichole comes to South Park Elementary, Cartman, thinking that blacks belong together, tries to play matchmaker with her and Token. When he learns that the girl has a crush on Kyle, Cartman spreads a rumor about Kyle in order to maneuver Token and Nichole together.

Randy's sarcastic protests over attempts to make football safer leads to the creation of a new sport, Sarcastaball, and an unusual tactic on the part of Butters to improve the South Park team's morale.

The widespread lack of shame underlined by the lifestyles of morbidly obese people, including both Cartman and Alana "Honey Boo Boo" Thompson, prompts James Cameron to go on an underwater quest to find the bar of human decency and raise it.

After Ike witnesses his parents engaging in sexual roleplay, the men in the town come to believe that their wives are sleeping with UPS delivery men. Meanwhile, Cartman gets a security system for his house, but it is angered by the nonchalant responses of the agents who respond to its alerts.

When Butters starts becoming extremely aggressive and rude, his parents tell him that he is a native Hawaiian, and must journey to that island to take part in an adolescent rite of passage. When he goes there with Kenny, he becomes embroiled in a conflict between the Hawaiians and the mainland U.S.

In this parody of The Shining, Randy buys a Blockbuster Video store in the hopes of reviving the video rental business, but the obsolete business drives him mad. Meanwhile, the boys, dressed as the Avengers (including an in absentia Stan using his iPad's FaceTime) go trick or treating, and come face to face with a gang of serial killers.

When the public comes to believe that Jesus performed his miracles because he was using drugs, they cease wearing their "What would Jesus do?" wristbands, but Stan controversially refuses to take off his bracelet, which leads to both criticism and the creation of a new movement dedicated to nonconformity.