Ewido Anti Spyware

Each time i scan ewido finds Hijacker.Agent.a which i hae quarantined and deleted numerous times. It seems each time the pc is restarted this "thing" comes back. It is in the IE5 folder, which I have also deleted but it returns.
Can someone please tell me what to do. Nothing else finds this except Ewido.

Teluga.....I have a similar problem although it doesn't find it with every reboot. Ewido picks it up in my kids temporary internet files as a popup[#].htm.
Could this possibly be downloaded from a website that my kids may be visiting? Any answers out there?

"Could this possibly be downloaded from a website that my kids may be visiting?"
This is possible, there are "some" security holes in Internet Explorer, so if you visit some websites it is possible that these websites use these security holes of an unpatched system to install adware or other unwanted software.