Admin: must be taken routinely on sched to prev sx, take 1-2 weeks for

full effect.

Glucocorticoids:
Inhaled:
Inds
SEs
Admin

MOA: Dec inflammatory response by suppressing actns of WBCs

(neutrophils, eosinophils, lymphocytes), histamine, prostaglandins,

leukotrienes, interleukins. Keeps IgE from getting involved.

Ind: tx local inflammation of bronchiloes-chronic asthma, COPD. Used as prev of acute. Not effective at time of acute episode in progress. Initial tx asthma, COPD exac should include a bronchodilator (helps open

up bronchioles so corticos can get in deeper). Given in combo w bronchiodilator (long acting beta2) &/or anticholinergic) and possibly a a mast cell stabilizer or leuk modifier.