RbsD-like domain (IPR023750)

Short name:
RbsD-like

Domain relationships

None.

Description

RbsD is a component of the ribose operon. It was originally thought to be a high affinity ribose transport protein, but further analysis [PMID: 16731978] shows that it is a D-ribose pyranase EC:5.5.1.n1. It catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. It also catalyzes the conversion between beta-allofuranose and beta-allopyranose.

FucU is a component of the fucose operon and is a L-fucose mutarotase EC:5.1.3.n2, involved in the anomeric conversion of L-fucose. It also exhibits a pyranase activity for D-ribose [PMID: 16731978].

Both have been classified in the RbsD/FucU family of proteins. Members of this family are ubiquitous having been found in organisms from eubacteria to mammals.