The aim of this study is to identify families with hereditary chronic tubulointerstitial renal diseases , characterize the phenotype and screen for mutations in known genesis (UMOD, REN, TCF2, NPHP1). Genome wide analysis will be performed in families without mutations identified.

High blood pressure known for more than 10 years before the discovery of the renal disease.

Major cardiovascular before the discovery of the renal disease.

Chronic auto-immune or infectious disease.

Polycystic kidney disease with increased of the size of the kidneys

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Please refer to this study by its ClinicalTrials.gov identifier: NCT01312727