Bioorganic Synthesis - Oliver Seitz Group

Bioorganic Synthesis,
Nucleic Acid Chemistry,
Protein Chemistry

Our main interest pertains to the biopolymers including nucleic acids, proteins and glycoconjugates. We develop new approaches for the chemical synthesis of proteins and nucleic acids, as well as their hybrids. It is our aim to improve upon the repertoire of biomolecular tools for the interrogation of biological processes.

Read/detect nucleic acid sequences

To understand the function of RNA and RNA-regulated processes we use a new class of probe molecules, so called FIT-probes binding specifically to target mRNA in living cells and report hybridization by fluorescence enhancement.

It is one of the foremost challenges in the "post genome era" to unravel the function of newly discovered protein molecules. We believe that a true understanding of protein function can only be obtained at the molecular level.