Noroviruses (NoVs) are second only to the rotaviruses as etiologic agents of acute fulminant gastroenteritis in infants and young children worldwide. While only one species is currently recognized within the genus Norovirus, molecular epidemiological studies have demonstrated a marked ..., Abstract

Bats have been implicated as important reservoir hosts of alpha- and betacoronaviruses. In this
study, diverse coronaviruses (CoVs) were detected in 50 of 951 (positive rate 5.3%) intestinal
specimens of eight bat species collected in four provinces and the Tibet Autonomous Region of
China by ..., Abstract

We developed a Gaussia luciferase (Gluc) reporter replicon of West Nile virus (WNV) and used it to quantify viral translation and RNA replication. The advantage of the Gluc replicon is that Gaussia luciferase is secreted into the culture medium from cells transfected with Gluc replicon RNA, and the ..., Abstract

Coxsackievirus A16 (CVA16), together with enterovirus type 71 (EV71), is responsible for most cases of hand, foot and mouth disease (HFMD) worldwide. Recent findings suggest that the recombination between CVA16 and EV71, and the co-circulation of these two viruses may have ..., Abstract