EVALUATION OF THE EFFECT OF A FAT MODIFIED DIET ON HORMONES DURINGADOLESCENCE
NIH GUIDE, Volume 21, Number 36, October 9, 1992
RFP AVAILABLE: NCI-CN-25502-51
P.T. 34, AA
Keywords:
Nutrition/Dietetics
Metabolism, Lipid
Hormones
National Cancer Institute
The National Cancer Institute (NCI), Prevention and Control Contracts
Section (PCCS), intends to issue a Request for Proposal (RFP)
NCI-CN-25502-51. The Division of Cancer Prevention and Control, NCI,
is conducting a study to evaluate the effect of a fat-modified diet
on hormones during childhood and adolescence. The study is being
performed ancillary to the Diet Intervention Study in Children
(DISC), a randomized clinical trial sponsored by the Division of
Epidemiology and Clinical Applications, National Heart, Lung and
Blood Institute (NHLBI). The objectives of DISC are to determine
whether a fat-modified diet during childhood and adolescence will
lower LDL-cholesterol and to assess the feasibility and safety of
this diet. The objectives of the NCI ancillary study are to evaluate
the effect of this fat-modified diet on sex hormones and to correlate
characteristics of children and adolescents, such as age, Tanner
stage, anthropometry, diet, and physical activity, with sex hormone
levels. This solicitation seeks a contractor to store serum
specimens collected for DISC, develop and issue an RFP for a
laboratory to perform serum hormone assays, evaluate the offerors'
proposals, award a subcontract to the best qualified laboratory
offering the best buy for the Government, and monitor the laboratory
to ensure high quality work and fulfillment of contractual
obligations. This RFP will be available on or about October 2, 1992,
with responses due approximately six weeks thereafter. No collect
calls will be accepted.
Copies of the RFP may be obtained by sending a written request to:
Christine L. Ptak, Contract Specialist
Research Contracts Branch, PCCS
National Cancer Institute
Executive Plaza South, Room 635
9000 Rockville Pike
Bethesda, MD 20892
Telephone: (301) 496-8603
.