Denver is an important railway centre, being served by nine railways, of which the chief are the Atchison, ' Topeka & Santa Fe; the Chicago, Burlington & Quincy; the Chicago, Rock Island & Pacific; the Denver & Rio Grande; the Union Pacific; and the Denver, North-Western & Pacific, Denver lies on the South Platte river, at an altitude exactly m.

Pacific from Kansas City (1870, now also part of the Union Pacific), the Denver & Rio Grande (1871), the Burlington system (1882), the Atchison, Topeka & Santa Fe (1887), and other roads which have made Denver's fortune.

Other river ports, of less importance, are Concordia on the Uruguay river, San Nicolas and Campana on the Parana river, Santa Fe on the Salado, a few miles from the Parana, the city of Parana on the Parana river, and Gualeguay on the Gualeguay river.