Globally, young women aged 15–24 are most vulnerable to HIV, with infection rates twice as high as in young men, at 0.6%. This disparity is most pronounced in sub-Saharan Africa, where 3.1% of young women are living with HIV, versus 1.3% of young men. Each minute one young woman acquires HIV, accounting for 22% of all new HIV infections, with sexual transmission being the dominant mode of infection. Much remains to be done to ensure that young people are able to correctly identify ways of preventing the sexual transmission of HIV.