Israel trolled Iran on Monday with a gif from the film “Mean Girls” after Iranian Supreme Leader Ayatollah Ali Khamenei called for their complete annihilation.

Khamenei tweeted that Israel is a “cancerous tumour” that needs to be “eradicated,” and referenced the Palestinian “March of Return” movement which has seen several large-scale protests along the Gaza border in recent weeks.

The Israeli Embassy in the US responded to Khamenei’s colorful language with a gif from the 2004 film “Mean Girls,” in which Regina George, played by Rachel McAdams, says to Cady Heron, played by Lindsay Lohan’s character, “Why are you so obsessed with me?”