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Glasgow, UK, Sistemic Limited (Sistemic), the miRNA profiling company with headquarters in Glasgow, Scotland, announced today the expansion of its granted patent portfolio in both the European Union and in the USA.

Glasgow, SCOTLAND. Sistemic Ltd. Announced today that it has been successful in securing funding from Scottish Enterprise, under the SMART: SCOTLAND grant scheme, that will aid and accelerate the company’s plans to develop a range of exosome-based products and introduce them into the cell therapy market in the latter part of 2015.

Recent News

Glasgow, SCOTLAND. Sistemic Ltd. is excited to announce significant progress with the development of a miRNA-based assay for assessment of pluripotent stem cell (PSC) contamination in derived cell therapy products. The development is being undertaken in conjunction with LGC, the UK National Measurement Laboratory and Designated Institute for chemical and bio-measurement.

Sistemic Ltd. announced today the publication of its ground-breaking research, undertaken together with TiGenix, identifying a set of circulating miRNA biomarkers which could potentially be used, if further clinically validated, to stratify refractory rheumatoid arthritis patients, prior to treatment, into responders and non-responders to an allogenic cell-based therapy:

Our Products

Sistemic’s platform technology pioneering the approach and development of miRNA-based profiling tools to guide and support Cell Therapy (CT) product development and drug discovery and repositioning

Allows for robust miRNA profiling, customised multi-layered statistical analysis, and biological interpretation and identification of the key markers (KmiR’s™) of cell phenotype. Whilst also seeking to maximise the utility and value of the KmiR’s™ identified

Sistemic's methodologies can also be applied to define, qualify and validating miRNA biomarkers from biofluids and surgical samples for prediction, diagnostic, prognostic, monitoring, toxicity and end-point.

Sistemic’s highly curated knowledge from internal and external projects covering miRNA and cell therapy-based knowledge. The database includes kmiR™ lists from all analyses and high impact meta-data. The knowledgebase is fully integrated with SistemSeek™ literature database