IHC

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TTG result not available

Duodenum, Biopsy:
- Small bowel mucosa with increased intraepithelial lymphocytes, villous
architecture and crypt architecture within normal limits, see comment.
- Brunner's glands present.
- NEGATIVE for acute duodenitis.
- NEGATIVE for dysplasia.
Comment:
Focally, there are approximately 50 lymphocytes/100 enterocytes. Increased intraepithelial
lymphocytes is a nonspecific finding that may be seen in a number of conditions, including
infections (e.g. Helicobacter gastritis), and autoimmune disorders (e.g. Crohn's disease).
It is seen in celiac disease; correlation with TTG serology is suggested, if not done.

Block letters

SMALL BOWEL (DUODENUM), BIOPSY:
- SMALL BOWEL MUCOSA WITH INCREASED INTRAEPITHELIAL LYMPHOCYTES, VILLOUS
ARCHITECTURE AND CRYPT ARCHITECTURE WITHIN NORMAL LIMITS, SEE COMMENT.
- NEGATIVE FOR ACUTE DUODENITIS.
- NEGATIVE FOR DYSPLASIA.
COMMENT:
There are approximately 45 lymphocytes/100 enterocytes. Increased intraepithelial
lymphocytes is a nonspecific finding. It is seen in celiac disease; correlation with TTG
serology is suggested, if not done.

Alternate

DUODENUM, BIOPSY:
- SMALL BOWEL MUCOSA WITH INCREASED INTRAEPITHELIAL LYMPHOCYTES, VILLOUS
ARCHITECTURE AND CRYPT ARCHITECTURE WITHIN NORMAL LIMITS, SEE COMMENT.
- BRUNNER'S GLANDS PRESENT.
- NEGATIVE FOR ACUTE DUODENITIS.
- NEGATIVE FOR DYSPLASIA.
COMMENT:
Focally, there are approximately 50 lymphocytes/100 enterocytes. Increased intraepithelial
lymphocytes is a nonspecific finding that may be seen in a number of conditions, including
infections (e.g. Helicobacter gastritis), and autoimmune disorders (e.g. Crohn's disease).
It is seen in celiac disease; correlation with TTG serology is suggested, if not done.

Positive TTG

DUODENUM, BIOPSY:
- SMALL BOWEL MUCOSA WITH BRUNNER'S GLANDS AND AN INCREASE OF INTRAEPITHELIAL LYMPHOCYTES
(>50 LYMPHOCYTES/100 ENTEROCYTES), A PRESERVATION OF VILLOUS ARCHITECTURE AND CRYPTS
WITHIN NORMAL LIMITS, SEE COMMENT.
COMMENT:
The findings are consistent with celiac disease, Marsh classification 1.