Neurological Conditions

Neurological Conditions

The Interplay of Neurotransmitters & Mental States

The body is the theater for emotional and cognitive states. Whether mood or mental issues express themselves through behavior or physical functioning-neurotransmitters are one group of characters at play.

Memory and cognitive processes are heavily dependent on acetylcholine, a neurotransmitter known to decline with age.

Sense of tranquility is influenced by the calming effects of GABA, an inhibitory neurotransmitter.

Feelings of nervousness are influenced by glutamate, an excitatory neurotransmitter.

Perception is influenced by a healthy neuronal environment, particularly by the balance between GABA and

glutamate.

Mood, stressful feelings, and sense of well-being are influenced by the level of brain cortisol-a neurohormone that can become elevated during times of stress, which may impact serotonin.

Feeling happy, content, and relaxed is related to the level of serotonin, which is a common target for modulation

in conventional approaches.

Sleep and wake cycles are dependent on melatonin status-a hormone derived from serotonin and produced

in the pineal gland.

Addressing neurological health concerns

An estimated 1 in 4 Americans have mental health concerns. Neurotransmitter modulation is the primary goal

to address neurological health with many conventional products - which are not without adverse effects. In collaboration with a renowned neurologist, Metagenics has developed a natural, clinically successful family of neurological health products designed to nutritionally support brain function to influence neurotransmitter dynamics associated with specific cognitive and emotional states. Your guide to specialized neurological support In this clinical guide, you'll find product descriptions, recommendations, and a quick reference tool explaining how to support various aspects of neurological health:

Neuroprotection

Forgetfulness

Distracted mind

Nervousness

Negative mood

Occassional sleeplessness

Foundation Neuroprotection

Multidimensional Brain & Nervous System Support

Ceralin® Forte is formulated to provide well-rounded support for brain and nerve protection, addressing multiple pathways involved in neurological health. Designed to act within the brain and nervous system, this advanced formula features significant levels of grape seed extract, 5-methyl tetrahydrofolate, N-acetylcysteine (NAC), and acetyl-L-carnitine.

Suggested Nutritional Supplementation

Ceralin Forte® - Three capsules daily.

Ceralin Forte is formulated to provide well-rounded support for brain and nerve protection, addressing multiple pathways involved in neurological health.

Forgetfulness / Cognitive Function Decline

Acetylcholine Function

CerivaTM is formulated to support healthy cognitive function in those concerned about maintaining their memory by beneficially modulating the metabolism of the neurotransmitter acetylcholine. Designed to act centrally, within the brain, Ceriva features huperzine A, 5-methyl tetrahydrofolate, and alpha-tocotrienol (from Tocomin® SupraBioTM), which research suggests may be able to cross the blood-brain barrier.

Patient benefits:

Supports the healthy metabolism of acetylcholine, the primary neurotransmitter associated with cognitive

function and the formation and consolidation of memoriesu

Provides Tocomin® SupraBioTM and huperzine A for nerve cell protection against excitotoxic effects and other oxidative influencesu

Supports a healthy life cycle of neurons and other cells

Suggested Nutritional Supplementation

CerivaTM - 2 softgels daily.

Ceriva is formulated to support healthy cognitive function in those concerned about maintaining their

memory by beneficially modulating acetylcholine.

Exhilarin® - 2-6 tablets daily

Exhilarin is a proprietary blend of Ayurvedic herbs that are traditionally used to relieve stress, and to help maintain mental acuity and support overall well-being.

Ceralin® Forte - 3 capsules daily

Ceralin Forte is formulated to provide well-rounded support for brain and nerve protection, addressing multiple pathways involved in neurological health.

Wellness Essentials Blood Sugar Support is a combination of three premium supplements in convenient packets to provide essential vitamins and minerals, omega-3 fatty acids, antioxidants, and phytonutrients

to support healthy blood sugar levels already in the normal range and overall health when taken as part of

Distracted Mind / Attention Deficit Behavior

Dopamine Function

LuminaTM is designed to support healthy mental function and relaxation-issues related to proper focus, attention, learning, and memory-through modulating the metabolism of neurotransmitters such as dopamine, gamma- aminobutyric acid (GABA), and norepinephrine. Formulated to act centrally, within the brain, this advanced formula features docosahexaenoic acid (DHA) and LactiumPureTM-which research suggests are able to cross the blood-brain barrier-along with theanine for targeted neurological support.

Patient benefits:

Dopamine, GABA, and norepinephrine metabolism are implicated in executive brain functions such as

focus, attention, motivation, learning, and memoryu

Features LactiumPureTM, a patented, bioactive decapeptide that has been shown to support relaxation and a healthy stress response, possibly by influencing GABA

Provides theanine and DHA, which preliminary research suggests may positively influence the metabolism

of neurotransmitters such as dopamine, GABA, and norepinephrine

Suggested Nutritional Supplementation

LuminaTM - 2 softgels daily

Lumina is designed to support healthy mental function and relaxation-issues related to proper focus, attention, learning, and memory-through modulating the metabolism of neurotransmitters such as dopamine, gamma-aminobutyric acid (GABA), and norepinephrine.

Ceralin® Forte - 3 capsules daily

Ceralin Forte is formulated to provide well-rounded support for brain and nerve protection, addressing multiple pathways involved in neurological health.

Nervousness / Anxiety

GABA & Glutamate Balance

TrancorTM is formulated to support a sense of tranquility in those who may feel worried or nervous by beneficially modulating the balance between the calming influence of GABA and the excitatory effects of glutamate. Designed

to act centrally, within the brain, this advanced formula features the amino acids NAC and taurine-which research suggests may be able to cross the bloodbrain barrier-along with concentrated green tea catechins, vitamin B6, and magnesium malate for targeted neurological support.

Patient benefits:

Supports a sense of tranquility by modulating the balance between glutamate and GABA with NAC, green

tea catechins, and vitamin B6

Helps protect nerve cells from the excitotoxic effects of excess glutamate and other pro-oxidant influences with taurine and EGCG

Supports relaxation and a sense of calm with magnesium and vitamin B6

Suggested Nutritional Supplementation

TrancorTM - Four capsules daily

Trancor is formulated to support a sense of tranquility in those who may feel worried or nervous by beneficially modulating the balance between the calming influence of GABA and the excitatory effects of glutamate.

Serenagen® - 2-6 tablets daily

Serenagen is a classic, comprehensive herbal stress management formula targeting individuals who are

"stressed and wired".

Recommended uses:

Nervousness

Support for tranquility

CAUTION: Do not use if pregnant or nursing. Use with caution if patient has congestive heart failure or kidney disease, or is taking medication - including anticoagulants. Maintain adequate fluid intake while taking this product.

Occasional Sleeplessness / Sleep Disorders

Melatonin Function

BenesomTM is formulated to promote a restful, relaxed state and relieve occasional sleeplessness by beneficially modulating the metabolism of melatonin and GABA. Designed to act centrally, within the brain, Benesom features supplemental melatonin-which research suggests is able to cross the blood-brain barrier. LactiumPureTM-a patented, bioactive decapeptide with relaxing properties-and passionflower are added to round out this formula

for targeted neurological support.

Patient benefits:

Promotes restful, quality sleep for those with occasional sleeplessness

Features melatonin, a hormone naturally produced in the brain that helps regulate sleep,waking, and the body's circadian rhythm (or time clock)

Provides LactiumPureTM and passion flower, which may favorably modulate the metabolism of GABA

Suggested Nutritional Supplementation

BenesomTM - One tablet one hour before bedtime. A typical consumption range for melatonin is 1 mg - 3

mg for supporting occasional sleeplessness.

Benesom is formulated to promote a restful, relaxed state and relieve occasional sleeplessness by beneficially modulating the metabolism of melatonin and GABA.

Tran-Q® - 2-6 tablets daily

Tran-Q has been traditionally used to maintain a calm spirit, relax the body, and quiet the heart. According

to traditional Chinese herbology, a sustained intense emotional state causes a disharmony between liver

and heart energy resulting in nervousness and mild mood changes.

LuminaTM - 2-4 softgels daily

Lumina is designed to support healthy mental function and relaxation-issues related to proper focus, attention, learning, and memory-through modulating the metabolism of neurotransmitters such as dopamine, gamma-aminobutyric acid (GABA), and norepinephrine.

Recommended uses:

Occasional sleeplessness

CAUTION: Do not use if pregnant or nursing. For adult use only. Avoid use if patient has a history of seizures or depression, is taking benzodiazepine or sedating medication, or is consuming alcohol. Use with caution if taking antiocoagulants or other medications or if operating machinery. Not recommended for more than 2 consecutive months.

Negative Mood / Depression

The Cortisol Connection

SymphoraTM is formulated to promote a positive mood and mental well-being by beneficially modulating cerebral metabolism of the neurohormone cortisol. Designed to act centrally, within the brain, Symphora features 5-methyl tetrahydrofolate-which research suggests is able to pass the blood-brain barrier-along with DHEA and vitamin

D for targeted neurological support. Patient benefits:

Cortisol is a glucocorticoid hormone associated with mood, well-being, and stress response

Features DHEA, which research suggests may support a positive mood by modulating the effects of brain

cortisol during periods of stress

Provides vitamin D, a vitamin that has been associated with serotonin metabolism and a positive mood

Supplies neuroactive vitamin B12 and folate-cofactors in the synthesis of neurotransmitters such as

serotonin

Serotonin Function

Somnolin® is designed to support a positive mood and an alert, relaxed state during the day, while promoting recuperative sleep at night through beneficially modulating the metabolism of serotonin. This formula features clinically effective levels of 5-HTP and theanine in just one tablet daily.

Serotonin Uptake

St. John's Wort with ActiFolate and B12 is formulated to support a calm, positive mood with nutrients that may play a role in serotonin metabolism. This formula supplies clinically effective levels of standardized St. John's Wort leaf and flower extract combined with a bioactive folate blend and vitamin B12 in two tablets daily.

Suggested Nutritional Supplementation

SymphoraTM - Two tablets daily

Symphora is formulated to promote a positive mood and mental well-being by beneficially modulating

cerebral metabolism of the neurohormone cortisol.

Somnolin® - 2-4 Tablets daily

Somnolin features a complementary blend of nutrients, including 5-HTP, theanine, and targeted B

vitamins, to promote a restful, relaxed state and relieve occasional sleeplessness.

St. John's Wort - 1-2 Tablets daily

St. John's Wort contains 450 mg of a premium extract of St. John's wort standardized to 0.3% hypericins, combined with folates and vitamin B12.