Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Applications

Specificity and Use

Recognizes Testosterone, which promotes the development and maintenance of male secondary sex characteristics and is produced primarily in the testes. It is also produced in small amounts by the adrenal glands, ovaries and placenta. Synthetic derivatives of testosterone are used therapeutically in the treatment of breast cancer and for hormone replacement therapy. The following cross reactivities have been observed: Testosterone, 100%; 11-beta-hydroxy testosterone, 3.3%; 17-alpha-methyl testosterone, <0.1%; 5-alpha DHT, 0.8%; Estradiol, <0.1%; Progesterone, <0.1%;.