Home >> Your Questions About Genetic Engineering >> How do you remove Glyphosate from runoff water from agricultural land? How do you prevent glyphosate from entering the drinking water supply? How do you prevent glyphosate from contaminating our salmon? How do you prevent glyphosate from affecting huma

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QHow do you remove Glyphosate from runoff water from agricultural land? How do you prevent glyphosate from entering the drinking water supply? How do you prevent glyphosate from contaminating our salmon? How do you prevent glyphosate from affecting huma

Question submitted By: Konrad Roeder

How do you remove Glyphosate from runoff water from agricultural land? How do you prevent glyphosate from entering the drinking water supply? How do you prevent glyphosate from contaminating our salmon? How do you prevent glyphosate from affecting humans and wildlife?
Glyphosate acid and its salts are moderately toxic compounds in EPA toxicity class II. Glyphosate has been linked to the same birth defect that the Washington State Department of Health reported to have found a high incidence of – anencephaly.
Rull et al. provided evidence of an association between maternal exposure to glyphosate herbicides and anencephaly, a type of neural tube defect, as well as with neural tube defects (NTDs) in general [71,72]–consistent with retinoic acid-linked teratogenicity. Antoniou et al., J Environ Anal Toxicol 2012, S:4

You have a number of questions and comments, and I will try to address each one of them.

Having worked in our Product Safety Center and now in Stewardship, I can assure you that the safety of our products is of critical importance to my colleagues and me. When we see claims that glyphosate is associated with neural tube defects or any other adverse health effect, we take them very seriously and review all relevant information.

Let’s first talk about what we know about glyphosate. Glyphosate inhibits the growth of plants by blocking an enzyme found in plants. This enzyme is not found in humans, fish, birds, insects or any other type of wildlife. Glyphosate has undergone extensive toxicology testing over the last 40 years, with at least six separate toxicology data sets generated by different registering companies across the globe. These data are remarkably consistent, and there is no evidence in any of those studies that glyphosate produces neural tube defects, like anencephalitis. Glyphosate is registered in 166 countries around the world, and the consensus of regulatory authorities and scientific bodies (e.g. the World Health Organization) is that glyphosate is not carcinogenic, genotoxic, neurotoxic or immunotoxic, has no endocrine disruption potential and does not impact reproduction or cause birth defects. Glyphosate has an excellent toxicological profile and there is no scientific evidence that it poses a potential hazard to an unborn child.

The allegation that glyphosate is linked to cases of anencephaly in Washington state is simply not true. Researchers from the Centers for Disease Control (CDC) assisted the Washington State Department of Health (DOH) to investigate the affected pregnancies in a three-county area. A clear cause of the increased rate of anencephaly was not determined. The Washington State DOH emphasized the importance of folic acid supplementation for women of childbearing age and recommended monitoring private wells for nitrates because of their potential association with birth defects and other adverse health outcomes. Glyphosate was not mentioned as a potential cause in these cases by either CDC or the Washington State DOH.

The Rull et al. references cited by Antoniou et al. report the results of an epidemiology study where the authors linked the mother’s address with agricultural pesticide use reports of 59 products and crop maps. There was no observation of the pesticide applications and no actual measurement of maternal exposure to the pesticides; the mothers were considered ‘‘exposed’’ to a particular pesticide if any crop type within a designated radius (1,000 m) surrounding the mother’s residence was treated with that product. There was no verification of the mother’s addresses, and given that the addresses were self-reported by the mothers in some cases almost four years after the delivery of the child, there may be some recall error in the data. Rull et al. (2006) analyzed the data several ways and found that with one model, glyphosate was weakly associated with anencephaly, but modeled another way it had no association. Given that the one association is weak and not repeated in another model, limitations exist in the exposure assessment, no other epidemiology studies have reported an association between glyphosate and neural tube defects and there is no evidence of neural tube defects in toxicology studies conducted with glyphosate, this one publication does not provide any scientific evidence that glyphosate produces neural tube defects in humans.

GMOs can affect the environment in many ways, and this response discusses the many ways in which GMOs can benefit the environment and the impact GM crops have on the environment. The data in this response from Brookes and Barfoot is from 2013, updated information can be found in their most recent report here.
Additionally, these infographics are helpful in explaining how GMOs can help preserve the habitat and H2O, protect the environment and improve soil health.
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The topic of labeling can be discussed in many different ways. We hope the below information on labeling GM food addresses your question.
The issue of GMO labeling, the consumer choice and logistical impacts of labeling genetically engineered food is discussed in this response.
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About the Expert

I’ve held a variety of roles in Monsanto’s regulatory group since joining the company in 1991. Regardless of my role, whether it was in our Stewardship Group or as a Toxicologist in our Product Safety Center, my focus is on the safe use of our products.