Metabolomic profiles in short day, after bolting, single leaf analysis, Arabidopsis thaliana

Choose a data normalisation

The controls below visualise relative metabolite
concentrations normalised to fresh weight and internal standards. Please choose
from the normalisation radio buttons below to visualise this experiment with respect
to different reference points. You might use the mouse wheel to zoom the controls
or drag and drop to move the zoomed area. This page is undergoing active development
and might change without further notice in the future.

absoluterelative to averagerelative to median
relative to replica groupcotyledonleafshoot apical meristemPlease choose from the 6 normalisations for data visualisation!

Update in progress...

replica group correlations

The correlation and network plots below visualise
the statistical relationship between the replica groups based on the oberserved
metabolite profiles. The network plot is derived from the correlation such that
only positive correlations are converted into distances, Distance(i,j) = 1 - COR(i,j).
The edges are filtered for distances < 0.5. The plot can be zoomed and dragged by
using the mouse wheel and left mouse button.

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technical replicates (aka chromatogram) correlations

This correlation plot visualise the statistical
relationship between the chromatograms based on the observed metabolite profiles.
It is kind of 'zoom in' into the replica groups. The assumtion is, that chromatograms
within one replica group correlate very well. However, the correlation of chromatograms
between replica groups is much worse, depending on the similarity of the replica
groups.

metabolite correlations

The correlation and network plots below visualise
the statistical relationship between the identified metabolites based on their observed
profile accross replica groups. The network plot is derived from the correlation
such that only poistive correlations are converted into distances, Distance(i,j)
= 1 - COR(i,j). The edges are filtered for distances < 0.2. The plot can be zoomed
and dragged by using the mouse wheel and left mouse button.

This is a alert, as your browser does not support the HTML5 <canvas>
element. To enjoy the full functionality of the GMD, please upgrade to a HTML5 ready
Browser and enable JavaScript!

dendrogram view

The heatmap below can be zoomed and dragged
by using the mouse wheel and left mouse button, respectively! Please note, that
the order of columns in the control below does neither necessarily reflect the numerical
ordering of the replica group column names nor correspond to the column order of
the second heatmap.

sortable table based heatmap with boxplot extension

The table below can be sorted by clicking
the column headers. Metabolite links point to the metabolite details pages. The
table is initially sorted according to decreasing anova F-score values (metabolites
with large changes in relative concentration between the replica groups at the top
and metabolites with small concentration changes between replica groups at the bottom).
Please hoover the mouse over the table to see box plots of the metabolite concentrations
according to the replica groups.