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I have programmed hundreds of these. The radio may be receiving, but the speaker may be muted. If using a hand mic, have the mic "off hook" or ungrounded and try again. Does the front light flash while the radio is receiving? This indicates the radio is "hearing", just not passing the audio to the speaker. Is there something plugged into the audio jack in the back? Let me know. In 20-30 minutes most shops familiar with Vertex will know exactly what is happening.

Are you programming the radio or did you buy it used? In the programming, a radio can be set for receive only. The other possibility is a bad battery. A battery has a huge draw on transmit and may not actually send a signal. Think of it like trying to start a car. I encounter this issue weekly. (poor battery) Post more information if you want me to help you. Such as: do you have the software, is it a fresh battery. How old is the radio. Let me know.

In the software, there is a transmit inhibit feature. Also, if you try to program some frequencies outside what the radio is allowed to do, they will receive only. This is a Ham radio, not a business band radio. You cannot legally program business frequencies on it from 01/01/2013. It is not US FCC type accepted.

Beeps and flashes, well my radio does that only if I try to transmit while someone else is using the airwaves already. the radio tells me the Channel is in use, so you can't get on the air until the channel is clear.

Sometimes, some nasty person(s), will hold down their PTT button without saying anything thus blocking the channel with what is known as a 'CARRIER' signal.

Is this the reason you're not making it on air?

I hope this has resolved the issue, if so, nothing wrong with your radio.

The short answer to your question is: no, or "not readily". Here's why:

The Motorola 4900 radio operates in the FRS (family radio service) and GMRS (general mobile radio service) in the UHF band. This radio will work with any other FRS / GMRS band radios (no reprogramming of transmit and or receive frequencies is possible for these radios). The trick is that the numbering of the channels may differ from brand to brand ie: Ch1 on your Motorola may not necessarily be Ch1 on a Midland radio or other brand. A complete list of the frequencies and channel assignments for FRS /GMRS can be found on Pg. 17 of the manual. It is important to note that without a valid GMRS license, you are prohibited from transmitting on the GMRS only channels (Ch 15 through Ch 22). The combination GMRS/FRS channels (Ch1 through Ch7) and the FRS only channels (Ch8 through Ch14) are for individuals and family members that do not have valid GMRS licenses. If this is you, you should limit your transmissions to Ch1 through Ch14 only, as FRS does not require a license in the US. Unlicensed use of GMRS only Ch15 through Ch22 can result in fines and imprisonment if caught by the FCC.

Further complicating the issue are the so called "privacy tones". This is simply a very low or "sub-audible" frequency that is sent whenever transmitting. Motorola calls these "Interference Eliminator Codes". When another radio receiver is set to listen for a particular privacy tone, it stays silent until a transmission with the exact same privacy tone is detected. Again, these tones are listed in no particular order, but are generally listed as 1, 2, 3, etc. or a, b, c, etc. instead of the actual frequency in hertz. You can selectively set your radio to transmit & receive one of the 38 codes or, set the code to "0" to communicate with radio that do not offer these privacy codes - or does not use the same frequencies for these codes. You can read more on Motorola's codes on Pg. 19 of the manual.

The Motorola CP200 radio on the other hand is a commercial radio, and requires computer programming with Motorola software. The CP200 is offered as both Low & High sub-banded VHF and Low, Mid & High sub-banded UHF radios. You would need to have a CP200 that is designed to accept the Mid UHF band (438Mhz - 470Mhz) frequencies in order to program the 462Mhz & 467Mhz FRS / GMRS frequencies into it. The final obstacle would be what is called "FCC Type Acceptance". The CP200 is probably NOT Type Accepted for transmitting FRS/GMRS frequencies, and as such the Motorola dealer doing the programing might balk at putting them in. You can read a spec sheet on the CP200 here.