With the tip of a sharp knife, scrape seeds from inside of vanilla bean. Place in a small saucepan. Add the pod halves and 1/2 cup butter. Melt over medium heat. Reduce heat to medium-low. Continue to cook, without stirring, for 5 to 6 minutes or until butter becomes brown and fragrant. Remove from heat; cool slightly.

In a large bowl, combine 2 tablespoons brown sugar, 1 tablespoon flour, pears and pear brandy, if desired. Toss together until well mixed. Remove vanilla pods from butter and discard. Stir browned butter into the pear mixture.