In my opinion Plasma is the only desktop with the best scaling options and the best results. Everything works fine. There is no need to adjust the font sizes or other configuration. I simply choosed Scaling factor = 2 (--> system settings --> hardware --> screen and monitor --> display scaling).

But Plasma is also not perfect: Gnome-Apps (f.e. gThumb) or Apps like Pinta come with very tiny icons. And in LibreOffice the drop-down menu arrows are also very thin.