Further study details as provided by Rikshospitalet University Hospital:

Primary Outcome Measures:

Number of skin conductance fluctuations

Estimated Enrollment:

24

Study Start Date:

January 2006

Detailed Description:

Skin conductance (SC), in terms of numbers of skin conduction fluctuations (NSCF), amplitude and mean skin conductance level, reflect the activity in the sympathetic postganglionic cholinergic fibers which innervate the palmar and plantar sweat glands. Skin conductance, especially numbers of skin conductance fluctuations, may be a promising tool to monitor anesthesia. Atropine, an anticholinergic agent, acts as an antagonist on the muscarinic receptors of the sweat glands and inhibits their secretion in a dose-dependent way. The aim of this study was to find out to what degree SC is influenced by i.v. administration of atropine.

Study hypothesis: SC is not influenced by i.v. administration of atropine.

Eligibility

Ages Eligible for Study:

18 Years and older (Adult, Senior)

Genders Eligible for Study:

Both

Accepts Healthy Volunteers:

No

Criteria

Inclusion Criteria:

Patients in ASA-group 1-2

Operations (anal fissures, anal fistulas and haemorrhoids) lasting for less than one hour

informed consent

BMI <30

Exclusion Criteria:

Patients using any medication known to influence the autonomous nervous system

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Please refer to this study by its ClinicalTrials.gov identifier: NCT00328900