The unstoppable sandwich trend meets the revered Southern biscuit, and a new style of restaurant is born.

New York City The biscuits at 24-hour Empire Biscuit are "sturdy and fortifying," says co-owner Jonathan Price. "Late at night, drunk dudes will order three fried-chicken biscuit sandwiches drenched with hot sauce." 198 Ave. A; empirebiscuit.com.