Trenbolone is an anabolic and androgenic steroid, also known under the trade names Tren, Finaplex, Finadzhet and Parabolan. Initially used in veterinary medicine to increase appetite and increase muscle mass in livestock. Available in the form of esterified derivatives.

Trenbolone acetate. The most popular form of the drug, which has the shortest period of action. The ether is stored in the fat depots, the active substance is gradually cleaved into the blood. The short period of semi-destruction determines the high frequency of injections, which can be inconvenient for beginners. The average dosage of acetate varies from 50-100 milligrams every other day.

Trenbolone hexahydrobenzylcarbonate. A rare form of steroid that has not been on the market for a long time. Despite the fact that today produced enough fakes, you can still buy the original Trenbolone Hexahydrobenzylcarbonate. For example, the production of Balkan Pharmaceuticals (Moldova). Cyclohexylmethyl carbonate is injected once a week. The recommended dosage is 300 milligrams.

Trenbolone Enanthate. According to its pharmacological characteristics, the form is similar to cyclohexylmethyl carbonate. The period of validity is up to 10 days, the number of weekly injections is 1-2, the dosage is 300 milligrams.

In today’s article we will talk about one very cool drug with a powerful anabolic effect. This drug is a very strong substance (stronger than testosterone and nandrolone) and is used, as a rule, by professional athletes. His name is trenbolone. In this article you will get answers to questions such as: Trenbolone acetate and enanthate – what is it? Cycle: Trenbolone + Testosterone for cutting and mass! What should be the duration and dosage? PCT after the cycle!

Trenbolone (Parabolan, Tren, Finanject, Finaplex) is a very powerful drug that is used both for cutting and for recruiting lean muscle mass. Since tren is very strong, the chances of side effects increase (the stronger the drug, the higher the efficiency and the more side effects).

Trenbolone 100 bu ULTRACHEM

This drug has similarity with nandrolone, but there are fundamental differences in effects. After hitting the muscle, parabolan esters smoothly decompose with plasma lipase, which ultimately results in a prolonged flow of the active substance into the bloodstream. In total there are three types of this drug:

Trenbolone acetate.

Trenbolone cyclohexylmethylcarbonate (hexahydrobenzylcarbonate).

Trenbolone enanthate.

Trenbolone Acetate – is the shortest ether, so you can feel its effect the fastest. This is both an advantage and a disadvantage. The advantage is a quick effect and a quick exit from the body (in the case of strong side effects, you can quickly jump off the cycle). The disadvantage is too frequent injections (every day or every other day). But, as practice shows, frequent injections do not frighten anyone, since this type of simulator is the most popular and sought after.

Trenbolone Cyclohexylmethylcarbonate (Hexahydrobenzylcarbonate) is the longest ether, therefore, to feel it in action you need to wait a bit. This species has a half-life of 10 – 14 days and, accordingly, you can prick only 1 time in 10 days. This is very convenient, since you do not need to constantly perforate yourself and as a result, the risk of getting such side effects as hardening, redness and pain in those places where the injection was made is reduced. There is, of course, a lack of such a long air. The disadvantage is that after drug withdrawal, the hormonal recovery processes do not begin immediately (as is the case with acetate), but after a certain period of time.

Trenbolone Enanthate – is a long-acting ether, therefore, to feel it you need to wait a little. This species has a half life of 7 – 10 days. Usually the dosage is divided into 2 parts and prick 2 times a week. Such rare injections are very convenient, as the risk of getting side effects such as hardening, redness and pain in the places where the injection was given is reduced. There is, of course, a lack of such a long air. The disadvantage is that after drug withdrawal, the hormonal recovery processes do not begin immediately (as is the case with acetate), but after a certain period of time.

Trenbolone Acetate

Important information and effects of trenbolone:

Aromatization (conversion to estrogen): absent.

Method of administration: injections (as a rule, injections are made: intramuscularly in the buttocks, thighs or deltas).

Liver toxicity: minimal (if very large dosages) and absent (if small and moderate dosages).

Increases insulin-like growth factor by 200%.

Lowers cortisol.

Increased lean muscle mass.

Increased anti-catabolic effect.

Increases power performance.

Side effects of trenbolone:

Insomnia.

Increased blood pressure.

Possible manifestation of increased aggression.

Pimples and blackheads appear on the body.

Baldness.

Oily skin.

Reduced libido and flaccid erection (not a fact, but maybe).

If you do not abuse this drug (do not put in excess of the dose), the chance of serious side effects is reduced to a minimum. If everything is done correctly, there will be no problems.

№1. Cycle: Trenbolone Acetate + Testosterone Propionate

This cycle is perfect for those athletes who first decided to try the train. In case of individual intolerance or major side effects, you can quickly jump off the cycle (short air will quickly stop its effect, which is not true for long airs). This cycle can be used both for cutting and for a set of lean muscle mass.

Trenbolone acetate by finexal

General information about the cycle:

Cycle duration: 6 weeks.

Dosage simulator: 150mg per week.

Propionate dosages: 300mg per week.

PCT after a cycle of trenbolone + testosterone – present (we will use Clomid to restore the natural hormonal background).

Injections should be given in the morning (the best places for injections are: the gluteus muscles and quadriceps).

Tren and propionate need to be combined in one syringe to minimize “tren cough” (that is, it draws 50 mg of training equipment + 100 mg of propionate into a syringe).

All that is written above (dosages) is the starting point of movement. If you try Trenbolone for the first time, then I do not recommend increasing its dosage. You can increase the dosage of testosterone or add oral medication (stanozolol, turinabol), but do not change the dosage of trenbolone. If you are an experienced athlete, you can increase the dosage of the device to 300 mg per week.

№2. Cycle: Trenbolone Enanthate + Testosterone Enanthate + Stanozolol

This cycle can be used both for cutting and for a set of lean muscle mass. Suitable only for experienced athletes, as there are large dosages and duration of the cycle.

Trenbolone enanthate by AceLabs

General information about the cycle:

Cycle duration – 8 weeks.

Dosage simulator – 300mg per week.

Testosterone dosage – 500 mg per week.

Dosages of stanozolol – 40mg per day.

Stanozolol should be taken evenly for 10mg during the day.

Tablets should be swallowed after meals (with water) or dissolve under the tongue before meals.

PCT after a cycle of trenbolone + testosterone + stanozolol – present (we will use clomid to restore the natural hormonal levels).

Injections should be given in the morning (the best places for injections are: the gluteus muscles and quadriceps).

Tren and test need to be combined in one syringe to minimize the “tren cough” (that is, it draws 150 mg of simulator + 250 mg of testosterone into a syringe).

The last 2 weeks of the cycle, we change trenbolone enanthate – to acetate, and testosterone enanthate – to propionate (we switch to short esters so that after the cycle you can start pct).

Now you understand what trenbolone is and what kinds there are. Also, you know how to make the right cycle for cutting and mass. Do not forget that this drug is very strong and there is a risk of getting big side effects. Do not exceed dosages to minimize the appearance of side effects.

So.. What is trenbolone acetate? What is Tren? Trenbolone is an androgenic and anabolic steroid produced in the form of esterified derivatives. The drug is marketed under several trademarks; consumers may be known as “Parabolan”, “Finaplex”, “Tren” and “Finajet”. The steroid was first used to increase muscle mass and appetite in cattle in veterinary medicine.

Acetate is the most common form of trenbolone. This ether is characterized by a minimum period of validity, which is deposited in the fat depot. The active component begins to flow into the blood, gradually splitting off. The high frequency of injections is due to the short half-life, which may not be very convenient for beginners. Acetate is required to enter from 50 to 100 ml in a day.

Cyclohexylmethyl carbonate is the rarest form of this steroid. The situation is aggravated by the presence of a sufficiently large number of fakes, but it is possible to find the original form. It produces, for example, the Moldovan company Balkan Pharmaceuticals. Injections of Trenbolone Hexahydrobenzylcarbonate need 300 ml once every seven days.

Enanthate has pharmacological indicators similar to cyclohexylmethyl carbonate. Activity is up to 10 days. The volume of injections, administered 1 or 2 times a week, is 300 ml.

Steroid Profile

Trenbolone acetate by MaxPro Pharma

The binding capacity of Trenbolone is five times higher than that of testosterone. This steroid is one of the most effective for the growth of muscle mass and increase strength. We must not forget about the side effects of the drug, manifested in non-compliance with the optimal dosage or duration.

The popularity of the steroid among athletes is due to zero estrogenic activity, the lack of conversion under the influence of aromatase. This allows not to worry about excessive hydration – fluid accumulation, as well as gynecomastia. Testosterone production in the body is suppressed by the feedback mechanism and progesterone activity.

Athletes who take Trenbolone may experience the following side effects: sluggish erection, decreased libido, and even testicular atrophy. The progestin activity of the drug is very similar to Nandrolone, which is explained by the origin of the steroid, which is a 19-derivative testosterone. Binding of steroid and progesterone receptors and is the cause of decreased libido and the occurrence of gynecomastia.

Acetate and enanthate are found in the athlete’s body up to five months after the end of the cycle.

The effectiveness of the steroid Trenbolone

The drug has the following effects:

Increases muscle mass. This figure is up to 10 kilograms when using the cycle of Trenbolone Solo.

Burns fat. Increased reduction occurs due to the activation of growth hormone synthesis.

Increases libido and sexual desire during the cycle. When the steroid is canceled, the secretion of testosterone produced in the body is significantly reduced.

Increases insulin-like growth factor twice.

Reduces cortisol concentration.

Increases strength.

Trenbolone Solo Cycle

Shows high power. It is not intended for women and novices. The higher the steroid injected, the greater the chance of side effects. Improving the safety of the cycle allows for the strict adherence to recommendations that minimize negative manifestations:

Dosage. Increasing the optimal rate in order to increase performance and achieve a much quicker effect only leads to an increased risk of negative consequences. Eat per day can be no more than 50 ml of acetate and 300 ml of enanthate per week.

Graduation. You need to take the drug with the minimum dosage and increase the volume until it reaches the limit rate. This allows the body to adapt, and in the event of a negative reaction, stop the cycle promptly.

Trenbolone boosts muscle growth

If the steroid is taken for longer than 5 weeks, it is recommended to start drinking 500-1000 IU of gonadotropin in the second week, up to the third week after the cancellation of the cycle. Post-cycle therapy begins 14 days after stopping the use of enanthate, or 2-3 days after the abolition of acetate. So much time is required for the withdrawal of each form of Trenbolone. Clomid is best used. Instead, it can be used Toremifen, but Tamoxifen due to the enhanced progestin effect of Trenbolone is better not to take.

Endogenous testosterone is restored by using the booster from three weeks to a month. Increase the effectiveness of the cycle allows proper balanced sports nutrition.

Combined Cycles Trenbolone

Achieved as a result of taking a steroid, the effect of the accumulated mass is high, does not require amplification by other drugs. Trenbolone taken with Winstrol or Anavar during drying.

Combined cycle involves taking half of the optimal rate of each drug. The duration of use is not more than two months. Take antiestrogens is not required.

Reception of Trenbolone by professionals

To gain muscle mass at the professional level of athletes, it is best to use a combination of enanthate and nandrolone. The total duration of the cycle, depending on the goal set by the athlete, can reach up to 15 weeks. Such a long reception has its drawback, which consists in increasing the risk of negative consequences.

Pro bodybuilders often use trenbolone acetate with testosterone

Possible side effects

Trenbolone can cause the following negative effects:

high blood pressure;

baldness;

acne – acne;

excessive aggression;

excessively oily skin.

Steroid suppresses the production of its own testosterone. This can lead not only to a decrease in libido, but also cause atrophy of the testicles. As a prophylaxis of this side effect, gonadotropin and cabergoline are administered.

The drug has a moderate effect on the liver, is not toxic. Possible staining of urine in red is associated with the elimination of metabolites. The increase in the risk of side effects increases when used during the cycle of Clenbuterol or ephedrine.

Trenbolone Reviews

The most popular form of steroid is acetate, and cyclohexylmethyl carbonate is inferior in use by athletes even enanthate. Athletes taking a steroid, noted in their reviews a pronounced increase in both muscle mass and strength indicators. The use of the minimum dosage reduces the manifestations of negative effects. The only thing that confuses consumers is the price.

Trenbolone acetate before and after

Professionals are pleased with obtaining an impressive amount when using Nandrolone and Enanthate. This combination allows you to increase the impressive volume, but also increases the risk of side effects.

As a result, the body is induced by a cascade of immune reactions directed to the destruction and elimination of pathogens and cells infected by them. The cells – producers of interferon acquire the ability to develop enhanced interferon in response to the re-induction, caused by pathological agent. This property is preserved for a long time after discontinuation of the drug. Immunomodulatory effects due to the ability trenbolone acetate buyactivated hematopoietic stem cells, to normalize the balance of subpopulations of T-lymphocytes, stimulate effector parts of the immune system. Has a pronounced stimulating effect on the functional activity of macrophages and polymorphonuclear leucocytes, increasing their migration and phagocytic activity. Corrects tissue growth: Activates NK-cells enhances all forms of cytotoxicity, a positive effect on recovery trenbolone acetate side effects adhesiveness cells inhibits their proliferative and metastatic activity.

Pharmacokinetics

In intramuscular bioavailability is more than 90%. After administration of 100-500 mg maximum plasma concentration is reached after 15-30 minutes and is 8.3 mg / ml. After 5 hours, only minor amounts determined , after 6 hours in plasma not detectable. Excreted unchanged by the kidneys without being metabolized, a half-life of 1 hour. After 15-30 min after administration plasma begin to increase endogenous interferon titers, especially early and interferon. 2 revealed a peak content of interferon in the plasma of 70 IU / ml after 1.5-2 hours and 110 IU / ml at 8-10 hours after which the interferon content and begins to decline. After 24 hours, the concentration of endogenous interferons remains high enough to the original values returned through 46-48 hours after administration.

Indications

In a monotherapy or in combination therapy:

influenza and other acute respiratory viral diseases, including the background of immunodeficiency states;

infections caused by the virus Herpes simplex, Varicella zoster, Herpes simplex genitalis, including persons with disorders of the immune system

Pregnancy and lactation

The safety of Neovir ® during pregnancy and lactation has not been studied, and the drug is contraindicated during pregnancy and lactation.

Contraindications

Hypersensitivity of the drug. Pronounced impairment of renal function (creatinine clearance less than 30 mL / min). Autoimmune disease. Pregnancy and lactation, children under 18 years.

With care

Apply elderly patients.

Dosage and administration

The solution for injection is administered intramuscularly, single therapeutic dose is 250 mg (1 ampoule) or 4-6 mg per kg of patient body weight. If necessary, a single dose of the preparation can be increased to 500 mg.
The course of treatment, unless otherwise indicated, includes intramuscular injections of 7.5 trenbolone acetate buy 250 mg every 48 hours, course dose depends on the clinical picture. The duration of 8-12 days. Single prophylactic dose is 250 mg (1 ampoule) or 6.4 mg per kg body weight. With prolonged use of the recommended interval between injections 3-7 days.
When HIV for Injection is used in combination with specific antiviral drugs. The treatment course consists of 10 injections of 250 mg every 48 hours between injections. After the course, make a

break for 2 months. Perhaps the use of repeated courses indicated.

Side effects

In rare cases may cause allergic reactions such as skin rash. There are low-grade fever, local pain rapidly passing into the injection site. When poor tolerability or soreness at the injection site is recommended to introduce together with the local anesthetic solution (2 ml 0.25-0.5% procaine solution).

Overdose

Neovir cases of overdose has not been described.

Interacting ones with other drugs

Physico-chemical incompatibility and other undesirable interactions have been identified.

Trenbolone perfectly combines with other steroids, it is good as a basic, and additional drug. In particular, it works great in combination with testosterone, providing an increase in dry muscle mass and physical strength, warm up exercises. It does not retain fluid in the body, has a short trenbolone acetate buy detection period in the analyzes and has a fat burning effect, so it is suitable for use in preparation for the competition. As already mentioned above, the best effect is achieved in the combination of Trenbolone acetate with Stanozolol, in the pre-competition period, you can also use Masteron or Drostenolone. It should be noted that the fat-burning effect of the drug is achieved only if the level of estradiol in the blood does not exceed the norm.

Another positive quality of Trenbolone is the absence of pronounced viral side effects. This means that this steroid can be used not only by men, but also by women. Of course, the acceptable dosage for women is much less – not more than 100 mg of drug per week, but in that case the results often exceed expectations.

Cautions

Information about possible negative impact of the drug on the performance of potentially hazardous activities that require attention and fast reactions (driving and other vehicles, work with moving machinery, the work manager and operator, etc.) is missing.

A feature of supercoiled circularis sensitive to the rupture of one of the 9116 phosphodiester chemical bonds. Buy trenbolone acetate molecule with a single break the link loses supercoiled, passing in the relaxed circular form (the parent compound). In experiment stimulated human endothelial cell proliferation, comparable to recombinant vascular endothelial growth factor, and significantly stimulated the growth of blood vessels mouse. The drug is trenbolone acetate stack with designed as a medicament for reducing the incidence of amputation and mortality in a population of patients with chronic limb ischemia, particularly in patients who can not be carried over standard revascularization occlusive lesion of peripheral arteries.

How to take: solo and combination with other steroids

Despite the fact that Trenbolone acetate does not suppress its own production of testosterone, it does not aromatize, and generally it has a low incidence of side effects, it is recommended to take it in courses of 4-6 weeks duration. The optimal dosage is 50-100 mg per day, depending on the course objectives, the individual characteristics of the athlete and the dosages of others entering the course of steroids. Frequency of injections – every day or every two days. The drug is not buy trenbolone acetate alkylated by 17-alpha, therefore it is easily decomposed by the liver and has no toxic effect on it. Observing small breaks between doses, it is possible to increase the bioavailability of the active substance, but it does not have a significant effect on the final result.

Pharmacokinetics: no data

Indications for use: in the buy trenbolone acetate complex therapy to revascularization in ischemia of the lower limbs atherosclerotic (IIa-III degree by AV Pokrovsky-Fontaine).

Contraindications for use: Hypersensitivity to the drug. Children under 18 years old.

Pregnancy and lactation: The drug is contraindicated.

Dosage and administration

Preparation is administered intramuscularly, twice, at a dose of 1.2 mg every 14 days, possibly in place as close as possible to the ischemic site. Single drug according to instructions after standard treatment oral tren of skin aseptically administered fractionally few of injection so that the whole array of muscles affected segment was infiltrated with a solution.

Special instructions

Before applying the contents of the vial are added to water for injection in an amount of 1.2 ml. Wait for complete dissolution of the drug (for 5-10 minutes). Prior to administration to the patient should be dissolved at room temperature. Drug treatment should be carried out under the supervision of surgeons on an outpatient or inpatient setting, beer and bodybuilding.

The impact of the drug on the ability to drive vehicles, mechanisms: Caution should be exercised. Since buy trenbolone acetate data on the effect of the drug on the ability to drive, there is no mechanism. how much to inject for weight loss

Suppositories contain metronidazole, which has antibacterial and protivotrihomonadnyh mikoiazol action and having an antifungal effect.Metronidazole is an antibacterial agent and protivoprotozoynoe and is active against Gardnerella vaginalis and anaerobic bacteria, including anaerobic streptococci and Trichomonas vaginalis. Miconazole nitrate has a broad spectrum of action (especially trenbolone acetate results active against pathogenic fungi including Candida albicans – causative agent of thrush), is effective against Gram-positive bacteria.
Bioavailability in intravaginal application of metronidazole was 20%, compared to oral administration. After vaginal administration of the drug Neo-Penotran when the equilibrium concentration of metronidazole in plasma was 1,6-7,2 mg / ml. Systemic absorption of miconazole nitrate in this method of administration is very low (about 1.4% of the dose) of miconazole nitrate was not detected in the plasma.

Metronidazole is metabolized in the liver. The active metabolite is a hydroxyl. The half-life of metronidazole is 6-11 hours. About 20% of the dose is excreted unchanged in at night.

Indications

Vaginal candidiasis,

Bacterial vaginosis

Trichomonas vaginitis

Vaginitis caused by mixed infections.

Contraindications

Known hypersensitivity to the active components of the drug or its derivative, the first trimester of pregnancy, porphyria, epilepsy, severe liver function, patients under the age of 18 years due to insufficient data on the use in this age group, virgins.

Pregnancy and lactation

Suppositories can be used after the first trimester of pregnancy under medical supervision, provided that the anticipated benefits to the mother outweighs the potential risk to the fetus.

At the time of treatment should stop breastfeeding because Metronidazole passes into breast milk. Breast-feeding can be resumed after 24-48 hours after treatment.

Dosage and administration

Intravaginal use. According to one vaginal suppository and one at night vaginal suppository morning for 7 days. When recurrent vaginitis or vaginitis, resistant to other treatments, should be used within 14 days.

Vaginal Suppositories should be administered deep into the vagina using a disposable fingertips contained in the package.

Elderly patients (over 65 years): the same recommendations as for younger patients.

Side effects

In rare cases, there may be hypersensitivity reactions (skin rash) and side effects such as abdominal pain, headache, vaginal itching, burning and irritation of the vagina.

Local reactions: miconazole nitrate, as well as all other antifungal agents based on imidazole derivatives which are inserted into the vagina, may cause vaginal irritation trenbolone acetate results (burning, itching) (6.2%). Due to the vaginal mucosa inflammation in vaginitis, vaginal irritation (burning, itching) may be intensified after the introduction of the first suppository, or the third day of treatment, abdominal muscles. These complications are rapidly disappearing with continued treatment. With strong stimulation treatment should be discontinued. Systemic side effects are very rare, because the vaginal absorption of metronidazole in plasma level is very low. Side effects associated trenbolone acetate buy with systemic absorption of metronidazole include hypersensitivity reactions (rare); leukopenia; ataxia; mental changes (anxiety, mood lability), convulsions; rare: diarrhea, dizziness; headache; loss of appetite; nausea; vomiting; pain or cramps; change in taste (rare); constipation; dry mouth; metallic taste; fatigue.

OD

Data concerning human overdose in intravaginal application of metronidazole absent. However, when administered metronidazole in the vagina can be absorbed in sufficient quantities to cause systemic effects. Accidental ingestion of large amounts of suppositories gastric lavage may be performed if necessary. Thereafter improvement can be achieved in patients, ingested 12 grams of metronidazole. No specific antidote exists. Recommended symptomatic and supportive therapy. Symptoms of metronidazole overdose include nausea, vomiting, abdominal pain, diarrhea, generalized itching, a metallic taste in the mouth, movement disorders (ataxia), dizziness, paraesthesia, convulsions, peripheral neuropathy (including after prolonged use at high doses), leukopenia, dark urine. Symptoms of overdose of miconazole nitrate were not identified.

Cimetidine:can increase the trenbolone acetate results concentration of metronidazole in blood and increase the risk of neurological side effects.

Lithium: there may be a rise of lithium toxicity.

Astemizole and terfenadine:metronidazole and miconazole inhibit the metabolism of these compounds and increase their concentrations in plasma.

There are several forms of this steroid drug:

Trenbolone acetate (Finaplex, Finajet, Finadjekt) is the most popular, but because of too short a half-life, there is a need for frequent intramuscular injection of the drug. The dose of the drug ranges from 50 to 100 mg every other day;

Trenbolone cyclohexylmethyl carbonate has a longer action up to 12 days. The injections can be done once every 10 days or half a dose 1 time every 5 days to trenbolone acetate results avoid sudden changes in testosterone levels in the blood. The recommended dosage is 300 mg per week;

Trenbolone enanthate is similar in its effect to the previous form. The duration of the action is about 10 days. The injections should be done 1 time in 3 days. The recommended dose is 300 mg per week.

Do not overdo this steroid (increase the dose and duration of the course of admission), as the risk of side effects increases.

Special notes

Pre-clinical data show no specific risk to humans based on the results of standard safety research, pharmacology, toxicity of repeated doses, genotoxicity, carcinogenic potential, toxicity to the reproductive system.

You should avoid drinking alcohol during treatment and for at least 24-48 hours after the completion of the course because of possible reactions disulfiramopodobnyh. Caution should be exercised when using suppositories along with contraceptive diaphragms and condoms because of possible damage to the rubber suppository base.

Patients with a diagnosis of “Trichomonas vaginitis” should be simultaneous treatment of sexual partners.

Do not ingest or apply a different way!

Laboratory tests

to change the results in determining the level of liver enzymes, glucose (hexokinase method), theophylline and procainamide blood.

Effects on ability to drive and use machinery

Suppositories Neo-Penotran not affect the ability to drive and use machines.

In the presence of any alarm symptoms (eg, such as a large spontaneous weight loss, frequent vomiting, dysphagia, vomiting of blood or melena), and in the presence of gastric ulcers (or suspected it) to exclude malignancy development, as trenbolone acetate powder treatment with esomeprazole can lead to a smoothing of symptoms and, thus, delay the correct diagnosis.

What does trenbolone acetate do

if there is a history of stomach ulcers or operations on the digestive tract;

during continuous symptomatic treatment of indigestion or heartburn for 4 or more weeks;

the development of jaundice or severe liver disease;

patients older than 55 years with the appearance of new symptoms of the gastrointestinal tract or a change in recent years is already available;

if necessary, endoscopic procedures or urea breath test (determination of Helicobacter pylori).
patients with recurrent symptoms of dyspepsia / heartburn or taking the drug for a long period (more than 1 year in particular) should be regularly monitored by the physician.

Trenbolone acetate powder

Do not use the drug Neo-zekst ®for a long time to prevent. Hypomagnesemia. Severe hypomagnesemia observed in patients treated with PPIs, such as esomeprazole, for at least three months, and in most cases the treatment for a year.There have been serious hypomagnesemia symptoms, such as chronic fatigue, convulsions, delirium, convulsions, dizziness trenbolone acetate powder and ventricular arrhythmia, but they can begin gradually and go unnoticed. In most patients, hypomagnesemia disappeared after supplementation of magnesium and discontinuation of PPIs. For patients who may require long-term treatment, or who are already taking PPIs together buy trenbolone acetatewith digoxin or drugs that may cause hypomagnesemia (eg, diuretics), physicians should consider measuring magnesium levels before starting reception PPI and periodically during treatment. fractures. Use of PPI, especially in large doses and for long periods (> 1 year) may result in a modest increased risk of hip fracture, carpal bones and the vertebral bodies, particularly in the elderly in the presence of people or other known risk factors.

Research suggests that taking these drugs may increase the overall risk of fractures by 10-40%. To some extent this risk increase may be the result of other factors. Patients at risk for osteoporosis should be treated according to current clinical guidelines and take in the required amount of vitamin D and calcium. During treatment with PPIs gastrin plasma concentration increases as a result of reduced intragastric acid secretion. Patients taking PPIs in for a long time, often marked formation of cysts in the glandular stomach. These phenomena are caused by physiological changes as a result of inhibition of gastric acid secretion. Cysts are benign and regress.

Patients on therapy “on demand” mode should be instructed to contact their physician if symptoms change in character. Taking into account the concentration fluctuations of esomeprazole in the blood plasma in the appointment of the drug in the treatment of “on demand” mode, it is necessary to take into account the interaction of the drug with other drugs. In the appointment of esomeprazole for Helicobacter pylori eradication should be considered the possibility of drug interactions for all components of the therapy. Clarithromycin is a potent inhibitor of the isoenzyme of CYP3A4, therefore the appointment of eradication therapy in patients receiving other drugs metabolized with the participation of isoenzyme CYP3A4 (eg cisapride), it is necessary to take into account possible contraindications and interactions of clarithromycin with these drugs.

Treatment PPI may slightly increase the risk of gastrointestinal infections , agents which are Salmonella, Campylobacter and Clostridium difficile in hospitalized patients. esomeprazole may reduce the absorption of vitamin B12 due to hypo- or achlorhydria. This should be considered when using the drug in patients with a deficiency or with a risk of deficiency of vitamin B 12 during prolonged therapy. The tablets contain sucrose, therefore should not be administered esomeprazole for patients with hereditary fructose intolerance, glucose-galactose malabsorption or sucrase-izomaltaznoy failure.

In the period of treatment with trenbolone acetate powder may increase the concentration of chromogranin a, used for the diagnosis of neuroendocrine tumors, so it is recommended the abolition of esomeprazole at least 5 days prior to the study. Subacute cutaneous lupus erythematosus (PKKV). The use of PPIs is associated with very rare cases PKKV development. If there is a lesion of the skin, especially in open areas to sunlight, together with arthralgia, then the patient should promptly seek medical care, yoga for beginners and the physician should consider the decision to cancel esomeprazole. PKKV the treatment of IDUs in history can increase the risk of PKKV the use of other PPIs.

Trenbolone Acetate

How does trenbolone work on an athlete’s body?

Here are all the effects of this steroid on the bodybuilder’s body:

weight gain athlete due to muscle tissue;

reduction of fat mass due to increased production of growth hormone;

during the reception of the drug, the libido rises, and after its abolition it sharply decreases due to a decrease in the production of its own testosterone;

growth hormone increases almost 2 times;

the level of cortisol decreases;

increase of power abilities.

Special precautions for the destruction of unused medicinal product

No need for special precautions during the destruction of the unused drug Neo-zekst.

Effects on ability to drive vehicles, machinery

During treatment with esomeprazole should be careful when driving, mechanisms and refrain from doing so in the case of side effects such as dizziness (rarely) and blurred vision (rare). bulking steroids for sale oraltec pharmaceuticals where to buy topical steroid creams

At the moment, it describes very rare cases of intentional overdose. Oral administration of esomeprazole in a dose of 280 mg was accompanied by general weakness and symptoms of gastro-intestinal tract.Single dose of esomeprazole 80 mg did not cause any adverse effects.
The specific antidote is known. Esomeprazole is bound to plasma proteins, therefore, dialysis is ineffective. In case of overdose should be carried out is symptomatic and general supportive treatment.

Interaction with other drugs

The study trenbolone acetate price was conducted esomeprazole interactions only adult patients. Effect of esomeprazole on the pharmacokinetics of other drugs Low acidity in the stomach in the treatment of esomeprazole can reduce or enhance absorption of other drugs, the absorption of which depends on the acidity of the medium. Just as the use of other drugs that suppress acid secretion or antacids, esomeprazole treatment can lead to decreased absorption of ketoconazole, itraconazole and erlotinib, and increase the absorption of drugs such as digoxin. Simultaneous use of esomeprazole 20 mg / day and digoxin increases the bioavailability of digoxin, 10% (bioavailability of digoxin was trenbolone acetate resultsincreased by up to 30% in two of 10 patients). About digitalis intoxication is rarely reported, however, caution should be exercised when treating elderly patients with high doses of esomeprazole. An enhanced monitoring of serum digoxin concentration. It has been shown that some of esomeprazole is reacted with antiretroviral drugs. Mechanisms and clinical significance of this interaction is not always known. The increase in pH during treatment with esomeprazole may interfere with the absorption of antiretroviral drugs. It is also possible to isoenzyme CYP2C19 interaction level. With simultaneous use of esomeprazole and some antiretroviral drugs, such as atazanavir and nelfinavir, there is a decrease in the blood serum concentrations, so their simultaneous use is not recommended. The simultaneous use of esomeprazole (40 mg once daily) with atazanavir 300 mg / ritonavir 100 mg to healthy volunteers resulted in a significant decrease in the bioavailability of atazanavir (area under the curve “concentration-time» (AUC), C max and C min plasma decreased approximately 75%). Increasing the dose of atazanavir to 400 mg of an offset lower its bioavailability exposed esomeprazole. The simultaneous use of esomeprazole (20 mg / day) with atazanavir 400 mg / 100 mg ritonavir in healthy volunteers resulted in a decrease of atazanavir bioavailability by approximately 30% compared to the bioavailability when using atazanavir 300 mg / 100 mg ritonavir without a proton pump inhibitor (PPI). The simultaneous use of esomeprazole with other drugs in the metabolism of which isozyme is involved CYP2C19, such as diazepam, citalopram, imipramine, clomipramine, phenytoin, et al., May lead to increased concentrations of these drugs in the blood plasma and require dose reduction. This cooperation is especially important to remember when using esomeprazole “as necessary.” With trenbolone acetate price the simultaneous ingestion of esomeprazole 30 mg and diazepam 45% reduced clearance of diazepam, which is a substrate isozyme of CYP2C19. With the simultaneous ingestion of esomeprazole 40 mg and phenytoin have epileptic patients was increased by 13% residual concentration of phenytoin in blood plasma. In this regard, it is recommended control phenytoin plasma concentration at the beginning of esomeprazole treatment and its cancellation. Application esomeprazole 40 mg once a day resulted in an increase in AUC and C max of voriconazole (substrate isoenzyme CYP2C19) at the 15% and 41%, respectively . When using the oral dose of esomeprazole 40 mg patients receiving warfarin clotting time remained within acceptable values. However, several reported cases of clinically significant increase MHO index (international normalized ratio), while the use of warfarin and esomeprazole. In this regard, it is recommended monitoring INR at the beginning and the joint application end esomeprazole and warfarin or other coumarin derivatives. Application of esomeprazole 40 mg in healthy volunteers, once a day resulted in an increase in C max and AUC cilostazol is 18% and 26%, respectively ; for one of the active metabolites cilostazol increase was 29% and 69%, respectively. In healthy volunteers inside the simultaneous use of esomeprazole and 40 mg of cisapride by 32% and increased the AUC value of 31% increased T 1/2cisapride; C max cisapride plasma while not significantly changed. A slight lengthening the interval QT, which was observed during monotherapy cisapride, adding esomeprazole is not increased. It was noted pharmacokinetic / pharmacodynamic interaction between clopidogrel (loading dose of 300 mg / maintenance dose of 75 mg), and esomeprazole (40 mg / day), which leads to a decrease in the active exposure metabolite of clopidogrel in average and reducing 40% maximal inhibition of ADP-induced platelet aggregation in average 14%. When clopidogrel together with a fixed combination of esomeprazole (20 mg / day) and aspirin (81 mg / day) there was a decrease exposure of the active metabolite of clopidogrel by 40% compared to a monotherapy clopidogrel, with maximal levels of inhibition of ADP-induced platelet aggregation were identical . During observations and clinical studies have provided conflicting data on the presence or absence of an increased risk of cardiovascular events, however, should be used with caution in conjunction with clopidogrel esomeprazole. Some patients have noted an increased concentration of methotrexate in the background of a joint application with the PPI. When high doses of methotrexate should be considered a temporary cancellation of esomeprazole. With simultaneous use of esomeprazole and tacrolimus showed an increase in serum concentrations of tacrolimus, which must be carefully monitored and the dose adjusted accordingly. Also to be assessed renal function (creatinine clearance, glomerular filtration rate). It is shown that esomeprazole does not cause clinically significant changes in the pharmacokinetics of amoxicillin and quinidine. Studies evaluating the short-term simultaneous use of esomeprazole and naproxen or rofecoxib did not reveal any clinically significant pharmacokinetic interaction. The effect of drugs on pharmacokinetics of esomeprazole in the metabolism of esomeprazole involved isoenzymes CYP2C19 and CYP3A4. Combined use inside esomeprazole and clarithromycin inhibitor isoenzyme CYP3A4 (500 mg, 2 times daily) resulted in a twofold increase in AUC of esomeprazole. Simultaneous use of esomeprazole and a combined inhibitor of isozyme CYP3A4 and CYP2C19, for example, voriconazole may increase AUC esomeprazole to 280% . Typically, in such cases does not require esomeprazole dose adjustment. Dose adjustment of esomeprazole may be required in patients with severe hepatic impairment and if long-term it is used. Drugs that induce isoenzymes CYP2C19 and of CYP3A4, such as rifampicin and drugs St. John’s wort,while the use of esomeprazole may lead to a reduction of esomeprazole plasma trenbolone acetate price concentrations of by accelerating its metabolism.

How to take the course of Trenbolon solo

While reviewing anabolic steroids, it is sometimes difficult to make the right choice and will stop at the most effective drug. To date, anabolic drugs have become a commonly used drug for stimulating muscle growth and strength, not only among athletes, but also among young beginners. But not everyone wants to use Methane, Anabol, Danabol and other potent drugs in trenbolone acetate price their courses , because behind a quick success there are a lot of important cons. Many athletes were able to assess on themselves that fast fluid retention in muscles does not lead to good.

If you could realize that a set of muscle mass can be of high quality, then try to pay attention to the course of Trenbolon solo, because it is this steroid is considered an excellent base drug. It is produced only in the form of injections and to date the products of the Balkans and Vermoji company are considered to be the most qualitative and working. If you know little about this anabolic and want to try the first time for a non-complicated course, then using not high dosages will help you get the result and not run into a pimple.

All trenbolone acetate 100mg drugs are taken twice a day for 7 days; • prevention of relapse of peptic ulcers associated with pylori Helicobacter – esomeprazole 20 mg, 1 g of amoxicillin and 500 mg of clarithromycin. All drugs are taken twice a day for 7 days.

Subsequently, the dose is adjusted individually, the duration of treatment is determined by the clinical picture of the disease. Any application experience in the range from 80 mg to 120 mg per day of esomeprazole. In applying the drug at a dose greater than 80 mg is necessary to divide the drug twice a day. Renal insufficiency: correction dose is not required. Hepatic impairment:in mild to moderate hepatic impairment dose adjustment is required. For patients with severe hepatic impairment should not exceed the maximum daily dose – 20 mg. Elderly patients: correction dose is not required.

How to take trenbolone

reception begin with a small dose (check the reaction of the body to the drug, monitor the occurrence of side effects);

The course should not be longer than 6 weeks in the absence of gonadotropin;

Post-course therapy should begin 2 weeks after the end of the last course;

To restore the production of your own androgens, you trenbolone acetate 100 should start taking a testosterone booster from the first day of the last week of the course and take it for 4 weeks;

to get the necessary effect while taking the drug, take sports nutrition and a special protein diet.

The introduction of the drug by gavage

In appointing the drug by gavage

1. Place the tablet in a syringe and fill the syringe with 25 ml water and approximately 5 mL air. Some probes may require dilution of the drug in 50 ml of drinking water to prevent clogging of the probe beads tablets.

2. Immediately shake the syringe for approximately two minutes to dissolve the tablets.

3. Keep the syringe tip up and check that the tip has not clogged.

4. Enter the syringe tip into the probe, while still holding it upward.

5. Shake trenbolone acetate 100mg the syringe tip and turn it down. 10 ml immediately enter into the probe-dissolvedtrenbolone acetate powderpreparation. After the introduction of the syringe return to its previous position and shake (the syringe must be held the tip up to avoid clogging of the tip).

6. Turn the syringe tip down and enter another 5-10 ml of the drug in the probe. Repeat this procedure until the syringe is not empty.

7. In the case of the remainder of the drug in the form of sediment in the syringe, fill the syringe with 25 ml of water and 5 mL of air and repeat the operations described in paragraphs 5 and 6. For some probes for this purpose may need 50 ml of drinking water.

Application of pregnancy and during breastfeeding

At the moment there is not enough data on the use of esomeprazole during pregnancy. With the introduction of esomeprazole animals did not reveal any direct or indirect negative impact on the development of the embryo or fetus and impact on reproductive function. Introduction of the racemic drug also did not have any negative impact on the animal during pregnancy, childbirth and in the postnatal period. Should be prescribed to pregnant trenbolone acetate price women only if the expected benefit to the mother outweighs the potential risk to the fetus. A study of pregnant women Information (300-1000 pregnancy outcomes) showed no malformations or fetal / neonatal toxicity of esomeprazole. Use of the drug during breast-feeding is contraindicated. At the moment not enough data on the effect of esomeprazole on infants and young children. The effects of esomeprazole on fertility has not been observed in research involving animals with trenbolone acetate cycle the use of racemic drug.

In fact, Trenbolone acetate can be used in a separate course, but where is the best result in combination with other steroids. Although he has a powerful effect, in general, the results in building muscle mass are worse than testosterone. Even in veterinary medicine it is often used together with Estradiol or other steroids, rather than by itself. The same opinion is shared by experienced bodybuilders and professionals: if there is an opportunity to get a better result, then why not do it.

Just a few of its properties Trenbolone acetate resembles testosterone. First of all, it is a question of hyperplasia of muscle cells and an increase in the level of IGF-1 due to the activation of cells of satellites. Due to this property, acetate provides growth trenbolone acetate cycle not only in muscle mass, but also in strength, endurance, performance and the result obtained from training exercises. Even more expressed its positive qualities, it manifests in combination with oral Stanozolol.

Dosing and Administration

Inside. Tablets should be swallowed whole with some liquid. Tablets should not be chewed or crush. For patients with difficulty swallowing can dissolve the pills in half a glass of still water (do not use any other liquids as well as a protective shell microgranules can be dissolved), stirring up the disintegration of tablets, after which the suspension of microgranules should be drunk immediately or within 15 minutes and then refill the glass halfway with water, stir and drink residues. Do not chew or crush the microgranules. For patients who can not swallow tablets should dissolve in water and carbonated administered by gavage. It is important that the selected syringe and tube have been thoroughly tested. Instructions for the preparation and administration of the drug by gavage given in this section.

Adults and children from 12 years

Gastroesophageal Reflux Disease:

treatment of erosive reflux esophagitis – 40 mg esomeprazole once. per day for 4 weeks is recommended that an additional 4-week course of treatment in cases when after the first course of healing of esophagitis trenbolone acetate cycle does not occur or symptoms persist;

symptomatic treatment of gastroesophageal reflux disease – 20 mg once daily in patients without esophagitis. If, after 4 weeks of treatment, the symptoms do not disappear, it is necessary to conduct an additional examination of the patient. After elimination of symptoms you can go to the reception of the drug regime “if necessary”, ie taking esomeprazole 20 mg once a day at the resumption of symptoms. For patients taking NSAIDs, and belonging to the group of risk of developing stomach or duodenal ulcer, it is not recommended treatment in the “if necessary”.

Adults Peptic ulcer and duodenal ulcer in a combination therapy for the eradication of Helicobacter pylori: