Karen Willcox is Professor of Aeronautics & Astronautics in the Aerospace Computational Design Laboratory at the Massachusetts Institute of Technology. She is also Co-Director of the MIT Center for Computational Engineering. She holds a Bachelor of Engineering Degree from the University of Auckland, New Zealand, and masters and PhD degrees from MIT. Before joining the faculty at MIT, she worked at Boeing Phantom Works with the Blended-Wing-Body aircraft design group. Her research and teaching interests lie in computational simulation and optimization of engineering systems with two major research focuses. The first is model reduction for large-scale systems with applications in unsteady aerodynamics, flow control, uncertainty quantification, inverse problems, and decision under uncertainty. The second is multifidelity methods for design, with particular emphasis on aircraft system design.