A distinguished diplomat, scholar and statesman has said: "It is too much the habit of men who have more education than experience, more culture than perception, to desire to mold the policy of the future by avoidance of all cases of trouble in the past." This logic can be well applied to-day in medical research. I come before you not to present anything specially new, but to call your attention briefly to some of the clinical features of malaria as seen in the Mississippi Delta. I shall not attempt a dissertation on the life history of the parasites outside the body, nor to theorize on the relationship which exists between malaria and the much talked-of mosquito. We have been taught much about acute malaria. The biology of the parasites causative of the various forms of malarial fevers has been heralded to us from all quarters of the globe, by men