Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Caution is recommended in using sparfloxacin in children up to 18 years of age because similar medicines have been shown to cause bone development problems in young animals. However, your doctor may choose to use this medicine if other medicines cannot be used.

Geriatric

This medicine has been studied in elderly patients and has not been found to cause different side effects or other problems than it does in younger adults.

Pregnancy

Information about this sparfloxacin-oral-route

Pregnancy Category

Explanation

All Trimesters

C

Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Alfuzosin

Amifampridine

Amiodarone

Amitriptyline

Anagrelide

Apomorphine

Aripiprazole

Arsenic Trioxide

Artemether

Asenapine

Astemizole

Atazanavir

Azithromycin

Bedaquiline

Bepridil

Buserelin

Chloroquine

Chlorpromazine

Ciprofloxacin

Cisapride

Citalopram

Clarithromycin

Clomipramine

Clozapine

Crizotinib

Cyclobenzaprine

Dabrafenib

Dasatinib

Degarelix

Delamanid

Desipramine

Deslorelin

Disopyramide

Dofetilide

Dolasetron

Domperidone

Donepezil

Doxepin

Dronedarone

Droperidol

Ebastine

Eribulin

Erythromycin

Escitalopram

Famotidine

Felbamate

Fingolimod

Flecainide

Fluconazole

Fluoxetine

Formoterol

Foscarnet

Fosphenytoin

Galantamine

Gatifloxacin

Gemifloxacin

Gonadorelin

Goserelin

Granisetron

Halofantrine

Haloperidol

Histrelin

Hydroquinidine

Hydroxychloroquine

Ibutilide

Iloperidone

Imipramine

Itraconazole

Ivabradine

Ketoconazole

Lapatinib

Leuprolide

Levofloxacin

Lumefantrine

Mefloquine

Mesoridazine

Methadone

Metronidazole

Mifepristone

Mizolastine

Moxifloxacin

Nafarelin

Nelfinavir

Nilotinib

Norfloxacin

Octreotide

Ofloxacin

Olanzapine

Ondansetron

Paliperidone

Panobinostat

Paroxetine

Pasireotide

Pazopanib

Pentamidine

Perflutren Lipid Microsphere

Perphenazine

Pimozide

Pipamperone

Piperaquine

Posaconazole

Probucol

Procainamide

Prochlorperazine

Promethazine

Propafenone

Protriptyline

Quetiapine

Quinidine

Quinine

Ranolazine

Rilpivirine

Risperidone

Ritonavir

Saquinavir

Sertindole

Sevoflurane

Sodium Phosphate

Sodium Phosphate, Dibasic

Sodium Phosphate, Monobasic

Solifenacin

Sorafenib

Sotalol

Sunitinib

Tacrolimus

Tamoxifen

Telaprevir

Telavancin

Telithromycin

Terfenadine

Tetrabenazine

Thioridazine

Tizanidine

Tolterodine

Toremifene

Trazodone

Trimipramine

Triptorelin

Vandetanib

Vardenafil

Vemurafenib

Venlafaxine

Vilanterol

Vinflunine

Voriconazole

Vorinostat

Ziprasidone

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acarbose

Acetohexamide

Alogliptin

Benfluorex

Canagliflozin

Chlorpropamide

Dapagliflozin

Exenatide

Gliclazide

Glimepiride

Glipizide

Gliquidone

Glyburide

Insulin

Insulin Aspart, Recombinant

Insulin Bovine

Insulin Degludec

Insulin Detemir

Insulin Glulisine

Insulin Lispro, Recombinant

Linagliptin

Liraglutide

Metformin

Miglitol

Nateglinide

Pioglitazone

Pramlintide

Rasagiline

Repaglinide

Rosiglitazone

Saxagliptin

Sitagliptin

Tolazamide

Tolbutamide

Vildagliptin

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Aluminum Carbonate, Basic

Aluminum Hydroxide

Aluminum Phosphate

Betamethasone

Budesonide

Calcium

Corticotropin

Cortisone

Cosyntropin

Deflazacort

Dexamethasone

Dihydroxyaluminum Aminoacetate

Dihydroxyaluminum Sodium Carbonate

Fludrocortisone

Fluocortolone

Hydrocortisone

Lanthanum Carbonate

Magaldrate

Magnesium Carbonate

Magnesium Hydroxide

Magnesium Oxide

Magnesium Trisilicate

Methylprednisolone

Prednisolone

Prednisone

Sucralfate

Triamcinolone

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

Brain or spinal cord disease, including hardening of the arteries in the brain, or epilepsy or other seizures—Sparfloxacin may increase the chance of convulsions (seizures) occurring

Heart rhythm problems or

Heart or blood problems that could lead to heart rhythm problems—Sparfloxacin can cause heart rhythm problems

Kidney disease—Effects of sparfloxacin may be increased because of slower removal from the body

Sensitivity of the skin to sunlight (previous)—Increased risk of severe reactions to sunlight caused by sparfloxacin