Portlandia will woo you. Shack up downtown at The Nines, a historic department store that’s been refashioned into a stylish hotel. The streetcar stops right outside, and the city is crosshatched with bike lanes. But just pedaling along the Willamette River with a rental from Waterfront Bicycles may be all you have time for this weekend. Across the water, boho Burnside Street has record stores and cafés, while the Mississippi Marketplace in the Boise neighborhood offers a cluster of popular food carts (the Big Egg’s Monte Cristo has melted hearts). Farther south, on Division Street, Pok Pok serves Vietnamese street food-inspired fish sauce wings and drinking vinegars. About a mile away, caffeinate with a lauded ristretto at Stumptown Coffee Roasters. Back near downtown in the arty Pearl District, the Blue Heron at BridgePort Brewing Company is a sudsy delight, while the off-menu burger at Gabe Rucker’s Frenchy bistro Little Bird has the James Beard stamp of approval.

While You’re ThereNot enough to do in Portland? Visit Steve Jones, who was named best cheesemonger on the planet in the international Cheesemonger Invitational. His Cheese Bar will pair the right Oregon wine with your mac and can hook you up with the manchego of your dreams.