..7 Mb; for bacteria in a nutrient-poor, organism-sparse ocean surface water sample, EGS is as low as 1.6 Mb. The method also permits evaluation of completion status and assembly bias in single-genome sequencing projects...

Systematic association of genes to phenotypes by genome and literature mining

..We further present advances in delineating disease-causing elements that are affected by structural variants, and we discuss future directions for research on the functional consequences of structural variants...

Similar gene expression profiles do not imply similar tissue functions

..e., extracellular space or cell membrane). This suggests that the observed positive selection at the network periphery may be due to an increase of adaptive events on the cellular periphery responding to changing environments...

Analysis of copy number variation in the rhesus macaque genome identifies candidate loci for evolutionary and human disease studies