Keras Skin Care System

Evidence and Outcomes

Faster healing post procedure

Scientists at the University of Miami Miller School of Medicine have determined that application of ReplicineTM Functional Keratin® immediately after receiving a partial thickness injury to the skin results in 26% improvement in healing rate (2). Histological work identified the mechanism of increased epithelization as keratinocytes at the wound edge entering an activated phase and as a result migrating faster.
As a result, keragelTTM gives reduced downtime following microdermabrasion, chemical peels or laser treatments, so patients heal faster, and can complete intensive repeat treatments quicker.

Through an extensive clinical research programme in three countries and multiple centres of excellence in the care of RDEB, Replicine Functional Keratin in the form of Keragel T has been established as an effective tool in the management of wounds arising from RDEB. Specifically patients report more rapid healing of skin blisters and importantly, a more robust skin and reduced tendency to blister. See for example A Arbuckle, A case study series of the management of Epidermolysis Bullosa using Keragel T, Society of paediatric dermatology portland USA, July 10, R.Kirsner Use of topical keratin gel by patients with epidermolysis bullosa, Journal of the American Academy of Dermatology, March 2009 (Vol. 60, Issue 3, Supplement 1, Page AB202.

1.- Faster healing post procedure

Scientists at the University of Miami Miller School of Medicine have determined that application of Replicine Functional Keratin immediately post receiving a partial thickness injury to the skin results in 26% improvement in healing rate. (S Davis, et al., The effect of a keratin based dressing on the epithelialization of deep partial thickness wounds, Journal of the American Academy of Dermatology March 2009 (Vol. 60, Issue 3, Supplement 1, Page AB201)). Histological work has identified increase in keratin gene expression (KRT6A, KRT16 and KRT17) indicating that keratinocytes enter an activated phase and migrate faster.
In the laboratory, kerationcytes have been measured as migrating faster in response to injury in the presence of Replicine Functional Keratin.
This benefit translates directly to better healing post procedure Go to testimonials
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BETTER HEALING

Research on skin structure, British Journal of Dermatology 140 (1999) 1038 – 1047, has identified the importance of collagen 7 and collagen 4 in forming the basis of the dermal-epidermal junction in the skin, the point at which the two outermost layers of the skin join. Furthermore, the research has also identified that an absence of these specific proteins occurs at the base of wrinkles. Low levels of collagen 7 and 4 significantly contribute to poor skin appearance and wrinkle formation as a result of reduced integrity of the dermal-epidermal junction. Research published by the University of Miami Miller school of Medicine has demonstrated that skin cells grown in the presence of ReplicineTM Functional Keratin® express more collagen 7 and collagen 4 (3). This is the right form of collagen expressed at the dermal epidermal junction to strengthen it, build healthy skin structure, and reduce wrinkles.

Keras Microdermabrasion Cream:

Keras Eye Gel:

Reduces wrinkles around the eyes by 42% within 2 hours of application and improves
skin smoothness by 49%.

Keras Intensive Serum:

Keras Intensive Serum addresses and corrects many common skin concerns such as: after burn from sun exposure, dry skin, redness and irritation, and minor damage or abrasion.

Keras Night Renewal:

Bioactive peptides that activate collagen within the skin that will reduce the appearance of fine lines and wrinkles. Also improves hydration by 20% in 5 days.
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Keras Day Shield SPF 15:

Protects the skin from environmental damage and reduces skin roughness by 27% and wrinkle depth by 25%. Stimulates the body’s own glutathione production. Boosts the body’s own antioxidant system.

keragel for post procedures

The use of keragelTTM immediately after a peel, laser, or microdermabrasion procedure will help with the healing process. Application is very simple and streamlined to fit in with the normal treatment process in your practice.

Application

Conduct the chemical peel, microdermabrasion, or laser treatment following your normal protocol. Mix keragelT into the topical cream you normally use following on from the treatment, at a ratio of approximately 1:1. This may be a moisturizer cream, a topical antibiotic, or any cream you normally apply. Apply the mixture to the treated skin in a manner identical to your normal procedure. Allow the mixture to absorb in to the skin and gently massage into the skin in the same way you would as part of normal post procedure care. Continue the recovery process at home post procedure with Keras Intensive Serum. Indicated following the use of keragelTTM after the first 24 hrs and continued for 5-7 days or until skin is completely healed. Keras Intensive serum is applied twice daily after gentle cleansing.
* Use of the Keras Skin Care System maintains the results of procedures.

2.- BETTER HEALING

In a randomized controlled study on 17 volunteers by independent research institute AgResearch, New Zealand, skin moisture measurements made using a corneometer measured a 20% (p< 0.01) improvement in skin moisture following 5 days of treatment with Keras Night Cream and sustained for the duration of the 21 day study (data on file). This rapid and sustained improvement in skin moisture levels is attributed to the action of the Replicine Functional Keratin Night Cream formulation in building a healthy skin structure able to act as a moisture reservoir,

retaining the skin’s natural moisture through cellular deposition of the appropriate collagens, hyaluronates and other natural humectants created by the cell.

Builds natural skin structure

Forms new skin

Substantiation of these claims comes directly from the published data on wound healing and skin treatment detailed above.

3.- Rapid wrinkle removal

Rapid removal of wrinkles through a short term tensor effect is achievable through strong adhesion of high molecular weight film forming Replicne Functional Keratin proteins to the skin and resulting contraction of those proteins on drying to tighten the skin and remove wrinkles. The result is a dramatic 49% (p< 0.0056) reduction in skin roughness and 42% (p< 0.0056) reduction in wrinkle depth in 2 hours. In a study of 5 volunteers by independent skin research facility Dermatest Australia silicone profilometry was used to measure skin properties 2 hours after application of the Keras Eye Gel (data on file). ,

4.- Boost the body’s antioxidant system

The cell’s master antioxidant is glutathione, a natural defence mechanism and powerful scavenger of free radicals that the body chooses over and above all other components to defend against UV and environmental insult. Cells make glutathione from components based on the amino acid cysteine. Replicine Functional Keratin contains many times more cysteine than any other natural material, due to the sulphur rich nature of the keratin protein. The direct result of this is a statistically significant improvement in the body’s production of glutathione related enzymes, glutathione peroxidase and superoxide dismutase, following exposure to Replicine Functional Keratin, (R. Mcpherson, Nutrafoods, 70, 4(4), 2005).

5.- Reduces redness and inflammation

In laboratory tests undertaken by third party laboratory MDS Pharma, Replicine Functional Keratin protein has been demonstrated to reduce the production of prostaglandin E2 associated with inflammation and redness in cells stimulated to become inflamed (data on file). In further work in chronically inflamed tissue associated with chronic venous ulcers, substantially reductions in redness and inflammation were reported when using wound care products incorporating Replicine Functional Keratin technology, (C Hammond, M Than, J Walker. From the laboratory to the leg: Patient's and nurses perceptions of product application using three different dressing formats, Wound Practice and Research, 18, 4, 189-195, November 2010.).

testimonials

“As an aesthetician with twenty-two years of experience, skin resurfacing is my objective. Keragel, a hydrogel produced by Keraplast, has increased my revenue by decreasing downtime between appointments, allowing me to be more aggresive in my treatments and producing faster results for my clients. Where healing time between appointments required a week before, Keragel allows me to safely treat my clients as often as twice a week. Not only do my clients see a quicker end result, they have the luxury of resuming their normal routines without worrying about damage to their skin.
As the final step in all my treatments, Keragel gives me peace of mind knowing that my clients are starting the healing process immediately”.

“I have been the cosmetic industry for over 25 years and recently tried the Keras Skin care line. I started the regime in July and for the first time in a awhile I really saw a visual difference. Fine lines diminished, hydration and firming were obvious. It was exciting. I am a 59 year old female and will continue this program.”

-Lauren Boyar, Skincare Specialist-

“Since I have been using Keras products , I am thrilled!
The texture of my skin has changed in a matter of weeks , it feels so nice and I use half the make up I use too...I went to a friends house after using the products about two weeks she kept asking me if I had went to a doctor and had work done. Several lady have ask me what is going on I look younger !
I can wait till I can use all the products , I have a few brown spots that have gotten lighter , can wait till they are gone ...I would recommend it to anyone ..”

-Deb Huff, 58, Sandy Springs Ga-

testimonials

"I have been involved in the beauty business for over 20 years and have literally tried hundreds of products. I am religious about my skin care routine but am always looking for the holy grail of eye products. The 'eye gel' from Keras could be it! It has an immediate firming feel. Lightweight and greaseless, you have a refreshed and hydrated appearance to the tired skin around the eyes. I've used it under concealer with perfect application and applied at night to wake up with out puffiness. Certainly a different product from anything I have tried in the past."

- Lisa M. Cosmetic Professional-

“I started using Keras products in August, in a matter of days I saw improvement around my eyes, and my skin looks and feels the best it has ever been! These products are the best I have used, I'm hooked! “