Causes a slow progressive depressant flaccid paralysis, when injected into S.falculata blowfly larvae. Inhibits dose-dependently the total sodium (Nav) currents both in dorsal root ganglia neurons and in ventricular myocytes. Is toxic to mice by intravenous injection, but not by subcutaneous or intracerebroventricular injection. Produces antiarrhythmia in rat. Is then active on both mammals and insects.

Causes a slow progressive depressant flaccid paralysis, when injected into S.falculata blowfly larvae. Inhibits dose-dependently the total sodium (Nav) currents both in dorsal root ganglia neurons and in ventricular myocytes. Is toxic to mice by intravenous injection, but not by subcutaneous or intracerebroventricular injection. Produces antiarrhythmia in rat. Is then active on both mammals and in