Specific Therapies For Nonulcer Dyspepsia

A wide variety of agents have been used to treat nonulcer dyspepsia. Therapeutic efficacy for most agents is limited and biomarkers to predict responses to specific agents are largely lacking. There are however some useful observations that may improve clinical outcomes.

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FIGURE 30-1. Symptom Checklist-90-R subscale scores in controls and patients with nonulcer dyspepsia. Significant differences are seen for all scales with the most profound differences occurring on the somatization and depression scales. FD = patients with nonulcer dyspepsia. From Jones et al (2003).

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