Summariesfor RCN1 gene

Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved

regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid

residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible

biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this

protein localizes to the plasma membrane.(provided by RefSeq, Jan 2009)

GeneCards Summary for RCN1 Gene:

RCN1 (reticulocalbin 1, EF-hand calcium binding domain) is a protein-coding gene. Diseases associated with RCN1 include prostate cancer, and wagr syndrome. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is RCN3.