Preparation and Storage

General Info

Alternative names

D12Ggc2e

HJ 2

HJ2

JAG 2

JAG2

Jagged 2 precursor

Jagged2

Protein jagged 2

SER2

Syndactylism

see all

RelevanceJagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.

Cellular localizationCell Membrane

Recombinant Human Jagged 2 protein images

SDS-PAGE - Jagged 2 protein (ab114541)

ab114541 on a 12.5% SDS-PAGE Stained with Coomassie Blue.

References for Recombinant Human Jagged 2 protein (ab114541)

ab114541
has not yet been referenced specifically in any publications.

Publishing research using ab114541? Please let us know so that we can cite the reference in this datasheet.