Neuroplasticity refers to any change or modification in the central nervous system because of any adaptation or experience to environmental demands. Musical training and experience can lead to neuroplasticity because music requires cognitive and neural challenges that need accurate and precise timing of many actions, exact interval control of pitch not involved in language, and various different way of producing sound. It was also reported that a musician's brain is best to study neuroplastic changes. Therefore, the current review explored studies related to neuroplasticity in musicians' brains. Various database such as Medline, PubMed, Google, and Google Scholar were searched for the reference to neuroplasticity in musicians.