Biology is an informational science that critically depends on accurate measurements and standards. Whether quantifying the amount of protein in a cancer cell or how well an organism converts sugar to alcohol, measurements are the foundation for improving our understanding of biological systems to meet the next generation of health care needs. What’s next depends on our ability to measure key features— including the complex interplay of thousands of biochemicals that control living systems. MML activities are focused to meet these challenges by advancing protein measurements, bioimaging, DNA diagnostics, and health care measurements.