Calcium oxide is affirmed by the FDA as a generally recognized as safe (GRAS) direct food substance (21 CFR 184.1210).

Prolonged contact with wet cement, which is alkaline due to the reaction of water with calcium oxide to form calcium hydroxide, can result in full-thickness skin burns that may require surgical treatment.

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Calcium ( /ˈkælsiəm/ KAL-see-əm) is the chemical element with the symbol Ca and atomic number 20. It has an atomic mass of 40.078 amu. Calcium is a soft gray alkaline earth metal, and is the fifth-most-abundant element by mass in the Earth's crust. Calcium is also the fifth-most-abundant dissolved ion in seawater by both molarity and mass...