Hh Signaling

Aims To test our hypothesis that transgenic induction of miR-210 in mesenchymal stem cells (MSC) simulate the pro-survival effects of ischemic preconditioning (IPC) and that engraftment of PCMSC help in functional recovery of ischemic heart by miR-210 transfer to host… Read more

In unstimulated cells NF-κB transcription factors are maintained in the cytoplasm by inhibitory IκB proteins. necrosis aspect alpha-induced IκBα gene transcription and abolished NF-κB DNA binding activity due to the continued cytoplasmic sequestration of RelA(p65) by TD-IκBα. In vivo genomic… Read more

Mesenchymal stromal cells (MSCs) are multipotent adult stem cells which are recruited to the tumor microenvironment (TME) and influence tumor progression through multiple mechanisms. the mouse mammary excess fat pad but no tumor was created when five or ten 4T1… Read more

Colorectal tumor (CRC) is the third most common cancer in western countries. (miRNAs) a class of small endogenous non-coding single-stranded RNAs that play a role as post-transcriptional regulators has added new dimensions to the diagnosis and treatment of cancer. Because… Read more

Middle East respiratory system symptoms coronavirus (MERS-CoV) is certainly a recently isolated betacoronavirus defined as the etiologic agent of the frequently fatal disease in American Asia Middle East respiratory system syndrome. lines directly correlates using the lack or existence of… Read more

piRNA (PIWI-interacting RNA) is a germ cell-specific small RNA where biogenesis PIWI (P-element wimpy testis) family members protein play crucial jobs. examining the molecular mechanisms of piRNA production the principal digesting pathway especially. We discovered that glycerol-3-phosphate acyltransferase 2 (GPAT2)… Read more