This manuscript highlights two novel receptors for the sensing of bacterial products and provides the perspective that the other members of the NOD-like receptor (NLR) family apoptosis inhibitory protein (NAIP) family are further putative sensors for microbial products.

Inflammasomes are cytoplasmic protein complexes that sense microbial products and activate caspase 1, which leads to cleavage and activation of the cytokines...

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