Lipid Profile, Cardiovascular Disease & Mortality Events

Research Paper Title

Divergent Pathway of Lipid Profile Components for Cardiovascular Disease and Mortality Events: Results of over a Decade Follow-up among Iranian Population.

Background

Data regarding the impact of different lipid measures on cardiovascular diseases (CVD) and mortality events is not consistent. The researchers aimed to evaluate the relationship between different lipid parameters and incident CVD and mortality events in an Iranian population over a median follow-up of 11.9 years.

The same analyses were also repeated for tertiles of all lipid measures. Considering the absence of interaction between gender and lipid parameters, the researchers used a sex-adjusted analysis. For analyses of mortality events, prevalent CVD was adjusted as well (All p for interactions > 0.1).

Conclusions

These findings indicate divergent associations of TC, LDL-C, non-HDL-C, TC/HDL-C, TGs and TGs/HDL-C with CVD vs non-CV mortality, demonstrating a higher risk for the former and lower risk for the latter.