Bolton Wanderers v Aston Villa (Saturday, 3pm)

Bolton's manager, Gary Megson, will assess the fitness of the defenders Ricardo Gardner and Danny Shittu. Gardner limped out of last week's 1–0 defeat at Portsmouth after only 12 minutes with a hamstring injury and Shittu missed the trip to Fratton Park altogether with a calf strain. Yet Megson is hopeful both men will be available, which would leave the midfielders Mark Davies and Joey O'Brien as the only absentees, both with injured knees.

Aston Villa's Gabriel Agbonlahor is winning his battle to be fit after missing the 1–1 home draw with West Ham last weekend thanks to a calf strain suffered during the previous match, against Everton. He will be challenging John Carew and Emile Heskey for a starting place. Villa's manager, Martin O'Neill, has no fresh injury worries as his side look to end a run of 11 games in all competitions without a win.

Everton v Manchester City (Saturday, 3pm)

Everton's on-loan striker Jo will sit out tomorrow's clash with his parent club Manchester City at Goodison Park. The Brazilian's absence could see Louis Saha return to the team following the draw with Chelsea in midweek. Marouane Fellaini missed the game at Stamford Bridge because of a knee problem and his fitness will be monitored by the manager, David Moyes.

Manchester City will be without Craig Bellamy, Shaun Wright-Phillips and Pablo Zabaleta for the trip to Everton. But, although it has been suggested Bellamy will miss the remainder of the season with a knee injury, the manager, Mark Hughes, has not yet given up on the Welshman.

Nigel de Jong is a major doubt with a thigh injury as City step up their push for seventh spot, which would be enough to secure European football next term.

Fulham v Stoke City (Saturday, 3pm)

Fulham are missing their midfielder Simon Davies. The Welshman has had a scan on a stress fracture on his foot that has grown steadily worse and he could be ruled out for much of the run-in. The midfielder Giles Barnes (achilles) and defender Tony Kallio (virus) are also missing.

Stoke's manager, Tony Pulis, has been forced to reshuffle his side. James Beattie (thigh) and Danny Higginbotham (back) are both injured. Andy Wilkinson also has a back problem and is doubtful. With Mamady Sidibe, Amdy Faye and Salif Diao absent and having treatment, Pulis is short of options as his side aim to reach 40 points at Craven Cottage.

Hull City v Liverpool (Saturday, 3pm)

Daniel Cousin is likely to be involved after recovering from a back injury. The Gabonese forward was an unused substitute in the defeat at Sunderland last week but has trained all week and could replace Manucho in the starting line-up. Richard Garcia will also be in the squad following minor knee surgery and will boost the Tigers' attacking options as they look to move away from the relegation zone.

Liverpool's captain, Steven Gerrard, is still struggling with the groin problem that has forced him to sit out the last three matches. The Liverpool manager Rafael Benítez is hopeful, however, that Gerrard will be fit for next weekend's visit of Newcastle.

Manchester United v Tottenham Hotspur (Saturday, 5.30pm)

Gary Neville has been ruled out for a fortnight by Sir Alex Ferguson after injuring his foot against Portsmouth at Old Trafford on Wednesday. It means he will miss both legs of the Champions League semi-final against Arsenal and also the Premier League games against Tottenham tomorrow and Middlesbrough on 2 May.

However, John O'Shea is fit after injuring his ankle against Portsmouth and could be part of a United squad to face Spurs that also includes Wes Brown, who has come through two reserve outings this week without a reaction. Ryan Giggs will make his 800th appearance if he gets on the field.

The Tottenham centre-back Michael Dawson is still waiting for a scan on his ankle and will not face Manchester United. Roman Pavlyuchenko is also likely to be missing as he recovers from a back problem. Ledley King will require his usual check on his knee before being named in the starting XI, while on-loan Fraizer Campbell is ineligible to face his parent club.

West Brom v Sunderland (Saturday, 3pm)

West Bromwich will be without their key midfielder James Morrison. The Scottish international is ruled out with a heel problem which has dogged him in recent months. The striker Roman Bednar (hamstring) and central defender Shelton Martis (groin) are back in the squad. They have returned to training after missing three and two matches respectively.

Sunderland's Kieran Richardson is pushing for a recall after overcoming a calf injury. The captain, Dean Whitehead, is also back in training after a leg injury and is included in Ricky Sbragia's squad. Nyron Nosworthy is ruled out after hurting his hamstring playing for the reserves and George McCartney remains sidelined.

West Ham United v Chelsea (Saturday, 3pm)

West Ham hope to have Radoslav Kovac available again tomorrow. Kovac is likely to be the only addition to the squad that earned a point against Aston Villa last time out. That means the teenage striker Freddie Sears will again be included in Gianfranco Zola's matchday party.

Chelsea are without the midfielder Deco and defender Ricardo Carvalho for the trip to West Ham. The pair are struggling to regain fitness following hamstring problems but right-back Jose Bosingwa is included in the squad after recovering from a similar injury.

Joe Cole and Paulo Ferreira are out for the season with knee ligament injuries. The interim coach, Guus Hiddink, may also decide to rest some of his first-team regulars against the Hammers ahead of the Champions League semi-final against Barcelona on Tuesday.

Arsenal v Middlesbrough (Sunday, 1.30pm)

Arsenal will be without their leading scorer, Robin van Persie (groin), for the visit of Middlesbrough, but goalkeeper Manuel Almunia (ankle), striker Emmanuel Adebayor (hamstring) and defender Johan Djourou (knee) could all be available again. The left-back Gaël Clichy (back) is facing a battle to be fit for the first leg of the Champions League semi-final against Manchester United on Wednesday night.

The centre-half William Gallas (knee) is still out, while the long-term absentee Tomas Rosicky will also miss the rest of the season.

Middlesbrough's manager, Gareth Southgate, will welcome the midfielder Gary O'Neil back from suspension. O'Neil is back following two games on the sidelines after reaching 10 bookings for the season. The French midfielder Didier Digard, who has been out for two months with quadriceps and medial ligament injuries, could be involved after playing 65 minutes for the reserves in midweek, but Chris Riggott (ankle) is a doubt and Emanuel Pogatetz (knee) remains on the casualty list.

Blackburn Rovers v Wigan Athletic (Sunday, 4pm)

Blackburn will again be short of strikers with Roque Santa Cruz and Jason Roberts both still injured. There are now doubts over whether Santa Cruz (knee) and Roberts (metatarsal) will play again this season, but the manager, Sam Allardyce, at least has no fresh injury concerns.

Wigan's manager, Steve Bruce, has the luxury of a full-strength squad to choose from. The top scorer, Amr Zaki, has recovered from a hamstring injury and has impressed Bruce in training this week, while record signing Charles N'Zogbia is over a niggling knee problem.

Lee Cattermole returns from a four-match suspension to bolster the midfield, and Bruce has the option of pushing Paul Scharner back into the defence to accommodate him.

Erik Edman will again be on the bench as he returns to the ground on which he suffered a serious knee injury towards the end of last season.

Newcastle United v Portsmouth (Monday, 8pm)

Newcastle's full-back José Enrique could return after missing the last two games with a knee injury, but is due to resume full training over the weekend. The strikers Obafemi Martins (groin) and Mark Viduka (achilles) have suffered no reactions to their returns to action at Tottenham last Sunday, but Steven Taylor (ankle) and Joey Barton (fractured metatarsal) remain doubts.

Portsmouth are waiting on their forward David Nugent and defender Younes Kaboul with the pair suffering from thigh injuries. Nugent failed to come out for the second half against Manchester United on Wednesday after a challenge by Nemanja Vidic while Kaboul missed the game following a knock in the win over Bolton five days earlier. However, both are expected to benefit from the few extra days' rest.

Kaboul's return would enable Glen Johnson to revert to midfield at the expense of Jermaine Pennant. The midfielder Niko Kranjcar, however, is unlikely to feature although medical reports on his damaged ankle – also sustained against Bolton – suggest he will return before the end of the season.