SPANK

Claude about to collect packages of SPANK in the mission S.A.M. Notice the resemblance between these and the Hidden Packages.

SPANK is a drug first introduced in Grand Theft Auto III. This drug is most likely based off cocaine, as it comes in a white, powdery substance (the hidden packages in Liberty City are also white powder). It also shares similarities with meth, in that it takes a serious toll on the user's sanity (as seen in Kingdom Come). Produced by the Colombian Cartel and brought into Liberty City through several ways, the drug serves as a plot device throughout GTA III.

Trivia

It is a play on methamphetamine, nicknamed crank -- and heroin, nicknamed smack.

The word SPANK is a reference to the physical act of spanking, specifically -- knowing Rockstar -- spanking for sexual enjoyment. 'Spank' and 'smack' are related terms in this context, pertaining to hitting with the hand.