The Jets could enter next Sunday’s critical home game against New England without several important offensive players.

They already know they won’t have tight end Kellen Winslow, who entered Sunday’s 19-6 loss to the Steelers as their catches leader. Sunday was the first of Winslow’s four-game suspension for using a performance-enhancing substance.

There’s a chance they might not have their most talented wide receiver, Santonio Holmes, who sat out Sunday’s game with a sore hamstring. He also missed last week’s win at Atlanta.

On Sunday, when they Jets fell to 3-3, they also saw two now-valuable offensive players fall to injuries in the fourth quarter.

Receiver Clyde Gates hurt his left shoulder and didn’t return. Nor did running back Mike Goodson after injuring his left knee when trying to tackle linebacker Lawrence Timmons as he returned Geno Smith’s second interception.

Goodson was helped to the sideline and wasn’t in the locker room afterward when it was open to reporters. Gates was, and had his left arm in a sling. Gates declined to discuss his injury.

It marked a sour conclusion to an otherwise productive day for him. He led the Jets in catches (five) and was tied for second with seven targets. He had 36 receiving yards, third-most on the team, with a long of 11.

If the Jets don’t have Winslow, Holmes, Gates and Goodson against the Patriots, it will be a tall order to crack New England’s defense. No. 1 running back Bilal Powell, who carried nine times for 30 yards Sunday, also hurt his shoulder, according to coach Rex Ryan. But Powell returned to the game and said afterward that it wasn’t a significant injury at all.

The injuries Sunday weren’t just limited to the offense, which isn’t good news as the Jets prepare to face future Hall of Fame quarterback Tom Brady.

Cornerback Kyle Wilson left the game in the first half with a head injury and did not return. Isaiah Trufant, who played 14 snaps all season before Sunday, took his place as the slot/nickel corner.

Wilson was just the latest injury to the Jets’ secondary. Corner Dee Milliner missed his third straight game Sunday with a hamstring injury, but he said last week that he expected to be ready for New England. Corner Antonio Cromartie hyperextended his right knee in Thursday’s practice, but started Sunday.

Darrin Walls started opposite Cromartie. Walls took Milliner’s place for the second straight game. Wilson started for Milliner in the first game of his absence, a win over Buffalo. If Wilson can’t play against New England, Trufant might have a large role again, depending on how much Milliner is available.