The single rate codon model of non-synonymous substitution is ubiquitous in phylogenetic modeling. Indeed, the use of a non-synonymous to synonymous substitution rate ratio parameter has facilitated the interpretation of ...

ENGLISH ABSTRACT: Two procedures to compute the output distribution 0S of certain stack filters S (so
called erosion-dilation cascades) are given. One rests on the disjunctive normal form of S
and also yields the rank ...

Codon models of evolution have facilitated the interpretation of selective forces operating on genomes. These models,
however, assume a single rate of non-synonymous substitution irrespective of the nature of amino acids ...

ENGLISH ABSTRACT: While it was known that all models of a Horn formula can be generated in outputpolynomial time, here we present an explicit algorithm as opposed to the rather vague oracle-scheme suggested in the proof ...

ENGLISH ABSTRACT: The majority of nonlinear filters used in practise are stack filters. An algorithm is
presented which calculates the output distribution of an arbitrary stack filter S from the disjunctive
normal form ...

Markov models of codon substitution are powerful inferential tools for studying biological processes such as natural
selection and preferences in amino acid substitution. The equilibrium character distributions of these ...

The problem of finding edge-disjoint trees in a hypercube arises for example in the context of parallel computing [3].
Independently of applications it is of high aesthetic appeal. The hypercube of dimension n, denoted ...

The imprint of natural selection on protein coding genes is often difficult to identify because selection is frequently transient or episodic, i.e. it affects only a subset of lineages. Existing computational techniques, ...

The present work investigates numerically the inherent irreversibility in a steady
flow of a couple stress fluid through a vertical channel packed with saturated porous
substances. The First and Second Laws of Thermodynamics ...

In 1852, in London, Francis Guthrie posed the question of colouring a map with four colours only, the question that eventually became known as the Four Colour Problem. The problem is famous, but what else do we know of ...

The size and shape of plant leaves change with growth, and an accurate description of leaf shape is crucial for describing plant morphogenesis and development. Bilateral symmetry, which has been widely observed but poorly ...

Motivated by topological quantum field theory, we investigate the geometric
aspects of unitary 2-representations of finite groups on 2-Hilbert spaces,
and their 2-characters. We show how the basic ideas of geometric ...

Biological invasion remains a major threat to biodiversity in general and a disruptor to mutualistic interactions in particular. While a number of empirical studies have directly explored the role of invasion in mutualistic ...

Background: This paper considers automatic segmentation of the left cardiac ventricle in short axis magnetic
resonance images. Various aspects, such as the presence of papillary muscles near the endocardium border, makes ...

Agent-oriented programming techniques seem appropriate for developing systems that operate in complex, dynamic, and unpredictable environments. We aim to address this requirement by developing model-checking techniques for ...

The evolution of substitutions conferring drug resistance to HIV-1 is both episodic, occurring when patients are on
antiretroviral therapy, and strongly directional, with site-specific resistant residues increasing in ...