In vitro protein secondary structure detection

Plasmonic nanoantennas offer new applications in mid-infrared (mid-IR) absorption spectroscopy with ultrasensitive detection of structural signatures of biomolecules, such as proteins, due to their strong resonant near-fields. UltraChiral EPFL partners have introduced a non-invasive, label-free mid-IR nanoantenna-array sensor for secondary structure identification of nanometer-thin protein layers in aqueous solution. This novel sensor is a highly promising and versatile tool for in vitro structural analysis of thin protein layers. The research is published in the journal Light: Science & Applications.