Two men were killed and four others were injured in shootings Sunday night on the South Side as continuing violence brought to six the number of people fatally shot in the city on the first weekend of summer.

About 9:30 p.m., two men were sitting in a disabled vehicle in the 1500 block of East 76th Place in the Grand Crossing neighborhood when three people approached and at least one of them opened fire, police said, citing preliminary information.

Both men took off running, according to police.

One of them, a 22-year-old man, collapsed after being shot in the side as he fled. He was taken in critical condition to Northwestern Memorial Hospital, where he was pronounced dead, according to the Cook County medical examiner's office.

He was identified as Justin Jackson, of the same block where the shooting happened, a representative for the medical examiner's office said.

The other man fleeing the vehicle, who is 26, sustained graze wounds to his head and shoulder and was taken to Jackson Park Hospital, where he was listed in good condition.

The three suspects were seen running from the crime scene and a "flash message" with their descriptions was sent over police radio, police said. Soon after police took three people into custody outside a White Castle restaurant at 79th Street and Stony Island Avenue, a little more than three blocks from the crime scene, and confiscated a gun, police said.

Later, about 11:25 p.m., 18-year-old Eduardo Venagas was standing on the sidewalk in the 3300 block of South Bell Avenue in the McKinley Park neighborhood when three males approached and one of them opened fire, authorities said.

The teen was struck in the chest and grazed in the shoulder, Chicago Police Department News Affairs Officer Hector Alfaro said.

Venagas, who lived in the 3200 block of South Bell, was taken to John H. Stroger, Jr. Hospital of Cook County, where he was pronounced dead at 11:59 p.m., according to the Cook County medical examiner's office.

Police have no one in custody as they investigate the homicide.

In other shootings:

• Also Sunday night, a 22-year-old man was shot multiple times in the head as he stood on a street corner in the West Englewood neighborhood, police said. About 10:40 p.m., a gunman approached and opened fire at the corner of South Ashland Avenue and West 61st Street, striking the man with multiple gunshot wounds to the head, Alfaro said.

The man was taken in critical condition to Stroger hospital.

No suspects are in custody in the shooting.

• About 11:50 p.m. a 29-year-old man was shot in the right foot in the 7200 block of South Langley Avenue in the Park Manor neighborhood, News Affairs Officer Jose Estrada said. The man was walking on the street when another man across the street fired at him. He was taken in good condition to St. Bernard Hospital and Health Care Center.

No one is in custody in the shooting.

• A 29-year-old man was shot about 10:45 p.m. while walking on the sidewalk in the 6100 block of South Throop Street in the Englewood neighborhood, police said. A shooter approached and opened fire, striking the man in the back and the leg. He was taken to Stroger hospital, where his condition was stabilized.