As a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Takeda Pharmaceuticals North America, Inc. is among the top 15 pharmaceutical companies in the United States. Founded in 1998 to accelerate Takeda's global expansion into the U.S. market, Takeda started with three employees and is now one of the fastest growing pharmaceutical companies in the United States, employing more than 5,500 people.

Takeda's U.S. clinical development activities are conducted via Takeda Global Research & Development Center, Inc., which has a robust pipeline of compounds in multiple therapeutic areas including diabetes, cardiovascular disease, and gastroenterology.