The international drug control regime is broken. Past approaches premised on a punitive law enforcement paradigm have failed, emphatically so. They have resulted in more violence, larger prison populations, and the erosion of governance around the world. The health harms associated with drug use have gotten worse, not better. The Global Commission on Drug Policy instead advocates for an approach to drug policy that puts public health, community safety, human rights, and development at the center. I have listed the five pathways to ending the drug war recommended by the Global Commission on Drug Policy that I chair. (Other members of the commission, ranging from Kofi Annan to Paul Volcker to former Mexican President Ernesto Zedillo are listed after the recommendations.)