GFAP Antibody (GFA-02) Summary

Immunogen

The antibody reacts with the GFAP antigen.

Marker

Astrocyte Marker

Specificity

GFA-02 reacts with Glial Fibrillary Acid Protein (52 kD). GFAP is the major protein of glial filaments in astrocytes and ependymal cells. In the peripheral nervous system GFAP is found in Schwann cells. Source: A BALB/c mouse immunized with a crude preparation from porcine spinal cord.

Isotype

IgG1

Clonality

Monoclonal

Host

Mouse

Gene

GFAP

Purity

Protein A or G purified

Innovator's Reward

Test in a species/application not listed above to receive a full credit towards a future purchase.

Reactivity Notes

Packaging, Storage & Formulations

Alternate Names for GFAP Antibody (GFA-02)

FLJ45472

GFAP astrocytes

GFAP

glial fibrillary acidic protein

Background

Glial fibrillary acidic protein (GFAP) is a member of the class III intermediate filament protein family. It is heavily and specifically expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In addition neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Blogs on GFAP.

Beta Tubulin III and neurogenesisBeta tubulin III, also known as Tuj-1, is a class III member of the beta tubulin protein family. Beta tubulins are one of two structural components that form our microtubule network. While general tubulins play a role in a wide range of cellular pr... Read full blog post.

"Whats the Hap" with GFAP?Glial Fibrillary Acidic Protein (GFAP) is one of the major intermediate filament axonal proteins found in mature astrocytes, the star-shaped glial cells that comprise the majority of cells within the central nervous system (1). Astrocytes perform a wi... Read full blog post.

Contact Information

Product PDFs

Calculators

Concentration Calculator

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

Volume

=

Mass

÷

Concentration

Review this Product

Be the first to review our GFAP Antibody (GFA-02) and receive a gift card or discount.