RX Drugs Information:

DRUG DESCRIPTION

MiocholŪ-E (acetylcholine chloride intraocular solution) is a parasympathomimetic
preparation for intraocular use. It is packaged in a blister pack containing
one vial and one ampoule. The vial contains 20 mg acetylcholine chloride and
56 mg mannitol. The accompanying ampoule contains 2 mL of a modified diluent
of sodium acetate trihydrate, potassium chloride, magnesium chloride hexahydrate,
calcium chloride dihydrate and sterile water for injection.

The reconstituted liquid will be a sterile isotonic solution (275-330 milliosmoles/Kg)
containing 20 mg acetylcholine chloride (1:100 solution) and 2.8% mannitol.
The pH range is 5.0-8.2. Mannitol is used in the process of lyophilizing acetylcholine
chloride, and is not considered an active ingredient.

The chemical name for acetylcholine chloride, C7H16ClNO2,
is Ethanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride and is represented
by the following chemical structure: