Drug Design and Development (PCOL3012)

UNIT OF STUDY

This unit of study is designed to introduce students with a basic understanding of pharmacology to the field of medicinal chemistry associated with drug design and development. The course covers the fundamental aspects of drug discovery and development with reference to the essentials of chemistry and illustrates drug development with examples that include neuraminidase inhibitors and ACE inhibitors. The role of computers in drug design is emphasised by classwork and assignments on molecular modelling and structure-activity relationships. The course also extends to a section on the design of diverse pharmacological agents which include compounds for imaging by positron emission tomography (PET), and kinase inhibitors.

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