LOS ANGELES (AP) — Blake Griffin had 33 points and 12 rebounds, and the Clippers shot 71% in the first quarter on the way to their largest-ever victory over the downtrodden Los Angeles Lakers, 123-87 Friday night.

Darren Collison had 20 points and seven assists, J.J. Redick added 19 points in his return, and DeAndre Jordan had 13 points and 10 rebounds in the Clippers' third straight win and fifth in six games. They improved to 17-3 at home, second-best in the NBA.

The Clippers' previous biggest win over the Lakers was 31 points on Feb. 19, 1992. That Lakers team included James Worthy, Byron Scott and A.C. Green.

Kendall Marshall scored 16 points, and Wesley Johnson and Robert Sacre added 14 points each for the Lakers, who've lost four straight and 10 of 11. Pau Gasol had 10 points, eight rebounds and five assists. They had 21 turnovers and shot 34%.

Both teams were missing their resident superstars: Chris Paul has a separated right shoulder and Kobe Bryant has a fractured left knee, his second major injury this season.

The Lakers beat the Clippers by 13 points in the season opener in October.

Things sure have changed.

The Clippers under new coach Doc Rivers are fourth in the Western Conference standings; the injury-riddled Lakers are mired near the bottom under Mike D'Antoni.

The Lakers were so short-handed they had to re-insert starters Johnson and Sacre in the fourth, when the teams' second units matched up as fans began leaving Staples Center in droves. Marshall stepped on a referee's foot and rolled his ankle in the third, but stayed in the game.

The Clippers opened the game shooting a season-best 71% while scoring 43 points, most in a quarter this season. Redick scored eight of their first 12 points of the game after missing 21 games with a broken right hand and torn ligament in his wrist.

Griffin scored 18 points in the first, when the Clippers had runs of 10-0 and 14-0 in taking a 43-25 lead. The Lakers used a 12-2 spurt to close within one before Griffin and Jordan combined to score 12 of their final 14 points.

April 14, 2014: Minnesota Timberwolves forward Corey Brewer goes crowd surfing in the middle of a game against the Golden State Warriors. The Warriors went on to win a 130-120 shootout, clinching the 6th seed in the playoffs.
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April 13, 2014: Paul George and his Indiana Pacers got a much-needed win against the Oklahoma City Thunder, as his squad jousts with the Miami Heat for the top playoff spot in the East.
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March 18, 2014: On the day he was introduced as Knicks president, Phil Jackson joins former teammates Walt Frazier and Dick Barnett and Peter DeBusschere, son of Jackson teammate Dave.
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March 3, 2014: The night belonged to LeBron James, who put on a show for the South Beach crowd with a career-high and Heat-record 61 points in a 124-107 win over the Bobcats.
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March 2, 2014: Joakim Noah (13) sends Raymond Felton's (2) shot back where it came from as the Bulls rolled to a 109-90 win over the Knicks in Chicago. Noah wracked up a triple-double with 13 points, 12 rebounds and 14 assists.
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Feb 26, 2014: Dwight Howard (12) beat Blake Griffin (32) for an alley-oop slam here, but it wasn't enough for the Rockets, who fell 101-93 to the Clippers in a matchup of Western Conference contenders.
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Feb 24, 2014: Everyone knew he would take the shot, but the Knicks still couldn't stop Dirk Nowitzki (41), who hit the game-winning shot here at the buzzer to give the Mavericks a 110-108 win.
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Feb. 23, 2014: Brooklyn Nets center Jason Collins (46) attempts a shot during the second half against the Los Angeles Lakers. Collins became the first openly gay athlete to play in any of North America's four major professional sports.
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Feb. 5, 2014: Sacramento center DeMarcus Cousins attempts to save the ball from going out of bounds during the third quarter in the Kings' game against the Toronto Raptors.
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Jan. 26, 2014: It was another emotional night in Boston as Paul Pierce and Kevin Garnett returned for the first time since being traded to the Nets in July. Each only scored six points, but Brooklyn came away with a 85-79 win.
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Jan. 25, 2014: Thunder star Kevin Durant had his game face on for a 103-91 win over the 76ers, finishing with 32 points, 14 rebounds and 10 assists for his second triple-double of the season. Durant also scored 30 or more for the 10th consecutive game.
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Jan. 24, 2014: Carmelo Anthony was all smiles after he delighted the home crowd and lit up Madison Square Garden with a franchise and arena-record 62 points in the Knicks' 125-96 win over the Bobcats.
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Jan. 12, 2014: C.J. Miles (0) couldn't get to the bucket here against Jason Thompson (34), just as the Cavaliers had a tough time scoring against the Kings in a 124-80 loss. Sacramento's 44-point blowout was the biggest rout of the NBA season so far.
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Jan. 10, 2014: In an NBA first, the Heat and Nets wore jerseys with nicknames on the back. "The Truth" Paul Pierce (34) and the Nets got the better of "King James" LeBron James and the Heat in a 104-95 double-overtime win.
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Jan. 5, 2014: A frustrated Jose Calderon pleads his case with an official during the Mavericks' home loss to the Knicks. New York frustrated Dallas into a season low in points in a 92-80 win.
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Jan. 4, 2014: Kevin Love, right, got the better of Kevin Durant in this collision of All-Stars, but Durant and the Thunder got the better of Love and the Timberwolves on the scoreboard in Oklahoma City's 115-111 win.
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Jan. 1, 2014: Monta Ellis (11) played some tough defense on John Wall (2) here as the Mavericks locked down on the Wizards in the fourth quarter of an 87-78 win in Washington.
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Dec. 23, 2013: In the epitome of a size mismatch, the 7-0 Dirk Nowitzki shoots over the 6-3 Jeremy Lin during a Mavericks win over the Rockets. Nowtizki scored a game-high 31 points to move into 13th place on the all-time scoring list.
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Dec. 21, 2013: Damian Lillard does it all for the Portland Trail Blazers. The reigning Rookie of the Year hit the floor to corral a loose ball here and later hit the go-ahead three-pointer in a 110-107 home win over the New Orleans Pelicans.
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Dec. 19, 2013: No Big 3 was no problem for the Spurs. Even with Tim Duncan cheering from the bench and Manu Ginobili and Tony Parker also out, San Antonio edged Golden State on the road 104-102.
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Dec. 14, 2013: Washington point guard John Wall (2) wasn't happy with a call here or the Wizards' play in a 113-97 home loss to the Clippers. Wall finished with 24 points and 12 assists, but his Los Angeles counterpart Chris Paul answered with 38 points and 12 dimes.
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Dec. 11, 2013: It was an emotional night in Boston when former coach Doc Rivers returned to the TD Garden as a visitor. Rivers received a standing ovation during a video tribute to his nine years with the Celtics.
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Dec. 8, 2013: It was thumbs up all around in Laker Land when Kobe Bryant made his season debut eight months after suffering a torn Achilles tendon. Bryant's return was not enough, though, as Los Angeles lost to the Toronto Raptors.
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Dec. 6, 2013: Rockets guard James Harden (13) drives the ball on a fast break during the first quarter against the Golden State Warriors at the Toyota Center in Houston.
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Dec. 5, 2013: Iman Shumpert (21) and Andray Blatche (0) shared just a few of the many heated words exchanged between the Knicks and Nets in the battle of New York. Shumpert and the Knicks routed Blatche and the Nets in the first of four meetings this season.
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Nov. 23, 2013: Tempers flare during a third-quarter altercation between the Blazers and Warriors in Oakland. The fracas led to three ejections and six technical fouls during Portland's come-from-behind win.
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Griffin provided multiple highlight moments, slamming down a one-handed jam off an alley-oop pass from Collison. Another of Griffin's powerful dunks had former Clippers center Chris Kaman ducking out of the way before Jordan sealed the 14-0 run with a steal and monster dunk of his own.

The Clippers' reserves played most of the second quarter, extending their lead to 70-52 at the break.

The Lakers missed 18 of 20 shots in the third, when they scored just eight points and trailed 101-60 as Bryant looked on from the bench, his head propped in his left hand.

Griffin dominated the third, scoring 13 points. Jordan got a technical after he and Gasol exchanged words nose-to-nose. Griffin went on to hit a jumper over an outstretched Gasol.

NOTES: Veteran F Hedo Turkoglu worked out for the Clippers on Thursday. He has been without a team since he was released by Orlando last fall. "We're not doing anything anytime soon," Rivers said. … The Lakers fell to 6-13 on the road and 3-11 on the road against West opponents. … Injured Lakers G Steve Nash (nerve root irritation) has been working out on the court by himself. … Gilbert Arenas, currently out of the NBA, created a jam in the aisle at halftime when he stopped to take photos with fans. … Hall of Fame baseball manager Tom Lasorda drew shouts from fans as he made his way to his seat.