"Tonight, we honour the victims of the unimaginable violence that has taken place in Paris and around the world. France matters. Russia matters, Syria matters, Mali matters, the United States matters. The entire world matters and peace is possible," Leto said.

Dion's performance received a standing ovation and served as a poignant moment in the otherwise light-hearted show.

Over 120 people were killed in the ISIS-perpetrated Paris terror attack, with most of those victims attending the Eagles of Death Metal concert at the city's Bataclan venue, including the band's merchandise manager Nick Alexander.