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ALAMEDA — The Raiders released wide receiver Ryan Grant Wednesday in order to elevate linebacker Justin Phillips from the practice squad.Grant had just four receptions for 14 and was inactive in favor of J.J. Nelson in Sunday’s 34-14 loss to the Minnesota Vikings. In Week 2 against the Kansas City Chiefs, Grant had one reception in five targets for a loss of two yards.With Grant’s release, the Raiders have five wide receivers on the roster — Tyrell Williams, Hunter Renfrow, Nelson, Dwayne …read more

by Dr Jerry BergmanAn article in New Scientist titled “Sex Differences in Human Gene Expression” concluded that “Researchers uncover thousands of genes whose activity varies between men and women.”[1] Specifically, their study found 6,500 genes were differentially expressed. They concluded that men and women are distinctly dimorphic, consequently one result of this fact is that they have very dissimilar disease susceptibilities.[2] The sexual dimorphic traits result mainly from differential expression of the genes that exist in both sexes. These results strongly go against the current politically correct view that the only differences between males and females are a few minor plumbing variations and a couple of small hormones.Two researchers, Shmuel Pietrokovski and Moran Gershoni, evaluated organ-, tissue-, and individual-specific gene expression from the Genotype-Tissue Expression (GTex) Portal data base. Researchers from the Weizmann Institute of Science produced a comprehensive genetic map of the genes that are differentially expressed in men and women.[3]This was not the first research in this area. One study found that mutations likely accumulated in genes that produced sperm because these mutations were expressed only in men. As a result, harmful mutations that cause health problems or death in only half of the population are passed on by women who have no sign of the mutation. The result is even further evidence for the accumulation of deleterious mutations that leads to mutational meltdown, the exact opposite that is required for Darwinian evolution. Evolution is thus true, but going backwards.To explore if other genes were differentially expressed, Pietrokovski and Gershoni examined close to 20,000 protein-coding genes. Of these, around 6,500 were expressed more in one sex than the other. They found removal of these genes by death or reduced fecundity was lower in these genes, thus these gene were more likely to be passed on to the next generation, resulting the accumulation of deleterious mutations.[4]The study is just one example of the latest research that emphasizes the many genetic differences between males and females. More surprising is the same sexual differences that have been found in animals. Kathleen Gardiner, a neuroscientist at the University of Colorado School of Medicine in Aurora, found evidence of brain region sex differences in mice.[5] Other studies have documented that sex differences in mice exist that can affect cardiovascular health, liver disease, and even cancer risk. These and many other studies were published in the Journal of Biology of Sex Differences.The study is just one example of the latest research that emphasizes the many genetic differences between males and females.Researchers studying pigeons determined that the sexes showed notably different gene expression patterns.[6] The researchers found hundreds of examples of differential patterns of gene expression in the hypothalamus, pituitary, and gonads, and, if they had looked at every body structure, presumably they would have found hundreds more differences.These differences may be due to, or in addition to, differences caused by genomic imprinting, the epigenetic silencing that allows certain genes to be expressed in a parent-of-origin-specific manner. Also, an allele on the Y chromosome inherited from the father causes sexually selective imprinting, silencing hundreds of genes. As a result, only the allele from the mother is expressed. Epigenetic silencing involves DNA and histone methylation, attaching a methyl (CH3) group, to block expression of the gene without altering the genetic sequence. Likewise, the Xist (X-inactive specific transcript), a gene located on the X chromosome in placental mammals is a major effector of the X inactivation process, creating even more genetic differences.Update from Editor 5/10/17: Science Daily mentioned the Weizmann report on May 4. On May 9, a WND Exclusive report offered more “proof that a man can never become a woman.” The report includes multiple stories of transgender males outcompeting true biological women in sports. “A biological male can take hormones, surgically alter his body and identify as ‘female,’ but the procedures still won’t make him a woman, according to new evidence found by Israeli researchers,” the report begins. “That’s because there are at least 6,500 genes that contain sex-specific instructions for males and females.” President of Oklahoma Wesleyan University Dr. Everett Piper notes that the transgender craze invading our culture is actually anti-woman and anti-feminist, because it pretends womanhood is unreal. If anyone can claim to be a man one day and a woman the next, that’s tantamount to denying the very existence of the female. Feminists should be outraged.[1] Akst, Jef. 2017. Sex Differences in Human Gene Expression. The Scientist. http://www.the-scientist.com/?articles.view/articleNo/49347/title/Sex-Differences-in-Human-Gene-Expression/[2] Gershoni, Moran and Shmuel Pietrokovski. 2017. The landscape of sex-differential transcriptome and its consequent selection in human adults. BMC Biology. 15(7):1-15[3] https://www.gtexportal.org/home/[4] Weizmann Wonder Wander May 3, 2017. http://wis-wander.weizmann.ac.il/life-sciences/researchers-identify-6500-genes-are-expressed-differently-men-and-women.[5] Krisch, Joshua A. 2017. How Much Do Sex Differences Matter in Mouse Studies? February, 24. http://www.the-scientist.com/?articles.view/articleNo/48616/title/How-Much-Do-Sex-Differences-Matter-in-Mouse-Studies-/[6] https://www.nature.com/articles/srep45125.Dr. Jerry Bergman is a professor, author and speaker.Men and women are different in many major ways and the politically correct movement cannot change that fact. Every scientific test we have performed has documented this fact and now we know that many of these differences have a genetic basis.(Visited 847 times, 1 visits today)FacebookTwitterPinterestSave分享0read more

5 Outdoor Activities for Beating Office Burnout 4 Keys to a Kid-Safe App 12 Unique Gifts for the Hard-to-Shop-for People… Well, this is disappointing.As magazines make the transition from print to pixels, some publishers are using the move as an opportunity to jack up their prices – in some cases, to more than they were charging for print editions. And that’s for tablet versions that are too often crappy afterthoughts. To be fair, magazines are contending with legitimate financial concerns. Their advertising revenue has been declining and the historically discounted subscription rates they’ve charged for print delivery just aren’t enough to pay the freight. To cope, many publishers are asking readers to chip in more – on digital versions as well as print editions.There are some problems with driving up prices too much, though.For one, everyone knows it’s cheaper to distribute content digitally than to print it and mail it. Asking buyers to pay more for something that costs you less to deliver is the kind of tactic that makes many subscribers feel exploited. It’s a head-scratcher, if not a subscription-canceler. Sure, magazine makers may still be coping with meaty legacy cost structures. But that’s not our problem, is it? Readers Have Way More ChoicesThere’s also much more competition. Long gone are the days when magazines competed only with each other. Today, the entire Internet churns out content at a volume too great for any one human to keep up with – and it’s all instantly available at any time. In addition to traditional magazines gone tablet, there are the digital-only magazines, sitting right there on the skeuomorphic newsstand shelf. For every frustrated TIME subscriber, there’s a free download of the Huffington magazine, not to mention personalized, social-fueled digital “magazines” from Flipboard, AOL Editions, Google Currents, Zite and an ever-growing list of others. If Wiredjacks up its prices, there’s always digital mags from The Next Web and Engadet, not to mention the huge selection of tech coverage available through news aggregator apps and feed readers. How Publishers Have Fared With TabletsNot everyone in the publishing industry is enamored with the idea of publishing native tablet apps for readers to flip through. MIT Technology Review editor Jason Pontin vowed to kill his magazine’s native apps, citing high costs, technical challenges and the walled-off, un-Web-like nature of apps. The Financial Times famously pulled its iOS apps in favor of the HTML5 approach and isreportedly seeing more traffic and revenue since making the switch. Indeed, research has suggested that most readers prefer Web apps to native, platform-specific publications. 9 Books That Make Perfect Gifts for Industry Ex… Related Posts Tags:#digital publishing#iPad#ipad magazines#magazines#tablets john paul titlow Still, some magazines have done pretty well with their digital editions, especially when they bundle them with print. In the United States, tablet publications are the second highest-grossing category of apps on iOS, according to an independent audit. Time and Conde Nast are selling the most digital mags, with news and women’s interest magazines dominating those sales. Half of Wired‘s revenue now comes from digital, which is a rare but promising milestone for a legacy publisher. I still subscribe to Wired in print, and I appreciate the fact that the iPad edition comes at no extra charge. I also happily pay for Marco Arment’s experimental publication The Magazine, because it consistently publishes content I enjoy in relatively small doses, rather than flooding me with irrelevant features and full-page ads.“The Magazine was profitable from day one,” says Arment. “As subscribers increased past break-even, I’ve been able to reinvest the additional income into more articles, higher author payments, original illustrations, photos and a professional editor.”While Arment won’t disclose hard numbers, he says he’s satisfied with what he calls The Magazine’s “fantastic success.” By utilizing what publishing expert Craig Mod calls “compact publishing” and monetizing it fairly, Arment has managed to build a profitable, if small media business in an age when industry trend lines have the stubborn tendency to slide downward.There’s clearly a limit to how much people will pay for magazine-style content. And it’s not at all clear that number is rising instead of falling. Folks who want to remain in the publishing business need to figure out a hybrid model that works, and not just jack up their prices to make up for shrinking subscriber rolls. Digital Magazines SuckThe business model isn’t the only issue here. Just as important is the consensus that most digital magazines just aren’t very good. In far too many cases, subscribing to a magazine on your tablet means downloading a bloated, glorified PDF that hardly delivers the potentially magical experience the form factor allows. Even some of the digital-only magazines from online publishers mimic print page-for-page in disappointing pinch-to-zoom layouts. There are some promising alternatives. Wired‘s iPad app is pretty print-centric but at least the editors go to the trouble of adding multimedia bells and whistles. The Magazine takes an attractive minimalistic approach – both in terms of publication design and pricing.Traditional publishers may want to look to The Magazine for inspiration, as well as to social news aggregators like Flipboard and Zite, which have managed to produce truly addictive reading environments worthy of a slot in one’s home screen dock. Rethinking magazines for tablets will require publishers to get completely out of the print mindset. That means different layouts, lighter file sizes, deeper social integrations and yes, occasionally pointing readers toward content published by others. On the whole, digital magazines have a long way to go. When they get there, those of us who are most hungry for the news, analysis and entertainment they provide will happily pay up. Hopefully, there will be enough of us to make the best digital magazines into viable businesses.read more

The BJP in West Bengal is planning to rope in Hindutva preacher Swami Aseemanand, who was acquitted in the Mecca Masjid blast case earlier this week, to strengthen its base, its State unit chief said here on Thursday.“I have personally known Swami Aseemanand for a long time. I will talk to him and try to bring him to West Bengal so that he can work here. For a long time, he has worked among the tribals in Bengal. He can help us in a lot of ways,” BJP State president Dilip Ghosh said.A special anti-terror court on Monday acquitted the 66-year-old self-confessed monk and four others in the 2007 Mecca Masjid blast case, holding that the prosecution failed to prove “even a single allegation” against them.Aseemanand’s younger brother, Sushanta Sarkar, is presently secretary of the BJP’s Hooghly unit.Mr. Sarkar said he would be happy if his brother returned to the State to work. “Our entire family is dedicated towards the Sangh Parivar. If my brother comes to Bengal and wants to work here, we will be very happy,” Mr. Sarkar said.A science graduateAseemanand, who was born Naba Kumar Sarkar at Kamarpukur in West Bengal’s Hooghly district, completed his graduation in science in 1971.He became involved with right-wing groups from school, going on to work full time with the Vanvasi Kalyan Ashram in Purulia and Bankura districts of the State. It was at the ashram that Naba Kumar Sarkar was christened Swami Aseemanand in 1981.read more

The administration of eastern Assam’s Golaghat district had set a week’s deadline to Numaligarh Refinery Limited (NRL) to demolish a boundary wall erected on a major elephant corridor.The Supreme Court had on January 18 ordered NRL to remove the 2.2 km wall around its proposed township that included a golf course. The refinery was given a month’s time to comply.In a notice to NRL’s Chief General Manager (Human Resources) on February 14, the district’s Deputy Commissioner said the refinery should demolish the entire wall within seven days and ensure that the land so acquired was kept free of any barrier for facilitating the movement of elephants.The order, the notice pointed out, was in reference to the apex court’s order as well as that of the National Green Tribunal (NGT) in 2016.Environmentalists had objected to the wall the refinery had erected in 2011 in – as the NGT had observed later – a part of the 133.45-hectare Deopahar Reserve Forest which the Assam Forest Department notified a day after the Supreme Court’s order.The refinery received flak from wildlife activists when a seven-year-old male elephant died of haemorrhage in May 2015 after trying to force its way through the wall. Videos also captured herds trying to cross the high boundary wall with barbed wire in vain. In August 2016, the NGT ordered NRL to demolish the wall within a month, but only a 289-metre stretch was demolished.The refinery challenged the NGT order to demolish the entire wall, but the Supreme Court said “there cannot be any township as elephants have the first right on forest”.read more