They developed a drug for anxiety sufferers (a benzodiazapene) and found that it solidifies at temparatures at RTP. As such, they developed it as a sort of "sweet" - a jelly bean drug to be precise. Now, drug abusers dont like eating a drug, it sort of takes the novelty out of dangering yourself for a high. Benzodiazapenes are drugs that if you take, its very difficult to kill you, and so these druggies thought that melting the jelly bean sweet and injecting it would be a good idea to get a really quick high from the drug. So they did it, but the drug started to resolidfy in the major veins, meaning that blood flow was cut off to arms severely, leading to ischaemia. But, some drug was taking effect, so they didnt have the wherewithal to go to the hospital quick enough, so had to get their arms amputated cos by the time they were cognitive, the arms started to become gangrenous.