... I will certainly ask the questions you described in your reply to my father's Urologist this week. I will ask about DRE and repeat PSA testing and probably a newer antibiotic for his bacterial infection. ... (38 replies)

... and that typically affects PSA. In fact, infection can affect PSA a lot and fast. It can drive PSA to very high levels. Then, when the infection wanes, the PSA often drops back to normal levels, only to climb again when the infection becomes more active again. ... (38 replies)

... ise. Other blood tests are often helpful before going ahead with a biopsy, though age is a factor. If you are young, say younger than about 50, that's a pretty highPSA. If you are in your 70s or older, that PSA is on the low side of normal. ... (3 replies)

... Catching the cancer early is the best cure. Like sparky0911 mentions, biopsies aren't fun, but it gives you valuable information. My PSA was 12, I had a normalDRE and no symptoms. I had a biopsy done and it came back cancer positive in 2 of the 10 sites. ... (58 replies)

... The score that's driving the concern in your case is that PSA of 15. If there might be some infection involved, which would also likely boost PSA independent of cancer, that could alter the picture a lot. ... (13 replies)

... or to a combination of some of these. You are probably most worried about prostate cancer with that PSA of 4.5, but cancer is not the most likely cause. While such a PSA is in the zone of concern, it is not a very highPSA. ... (1 replies)