Description:
Human CD3, a glycoprotein, consists of five polypeptide chains (gp20, gp26, p16, p20 & p28). The CD3 complex is involved in T cell activation and signal transduction. The CD3 antigen is T cell specific, and normally present in resting and activated T lymphocytes. It is also present in peripheral blood T cells and thymocytes. CD3 antibody is specific for T cells, and often used to distinguish precursor T cell lymphoblastic lymphoma from its B cell counterpart.

Applications:Suitable for use in Immunohistochemistry. Other applications have not been tested.

Recommended Dilution:Immunohistochemistry: Frozen and formalin-fixed paraffin-embedded tissue sections. Optimal dilutions to be determined by the researcher.

Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type

Isotype

Clone

Grade

Pab

IgG

Purified

Size

Storage

Shipping

Source

Host

1ml

-20°C

Blue Ice

Human

Rabbit

Concentration:

~0.05mg/ml

Immunogen:

Synthetic peptide derived from human CD3.

Purity:

Purified

Form

Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.1% sodium azide.

Specificity:

Recognizes both normal and neoplastic human T cells.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.