Drew didn't exactly run roughshod this time. But in the Jaguars' 31-24 loss to Indianapolis on Thursday, he continued to build onto a short legacy of domination against the Colts. Logging 20 carries in a game for just the fourth time in his career, Drew finished with 91 yards rushing and produced 162 yards from scrimmage.

"We played well, just not well enough," Drew said. "We did some great things, but we also did some things that are uncharacteristic of us. We've got to stay consistent."

Despite the solid performance, Drew's night ended on a sour note after he went down with a sprained knee in the final minute after catching two passes for 27 yards during the Jaguars' last drive of the game.

Team officials didn't immediately have an update on Drew's condition, but he didn't return after the injury.

However, Drew said he's fine.

"I'm all right. I'll definitely play next week," he said. "It's not a big deal, just a bruise. It's football. You get tackled and you get back up."

Of the six running backs taken in the first two rounds of the 2006 draft (a class that includes Reggie Bush, Laurence Maroney, DeAngelo Williams, Joseph Addai and LenDale White), Drew entered Thursday's game leading the class in touchdowns (40), yards from scrimmage (3,691) and all-purpose yards (5,653).

A good portion of those statistics came in games against the Colts.

"A lot of people thought he was going to go to the Colts in the draft," NFL Network analyst Cris Collinsworth said. "[Colts coach] Tony Dungy loved him. Instead, the Colts took Joseph Addai because they thought he was a little better of a blocker. But when you watch Maurice block, it's had to imagine anyone could be a whole lot better."

Drew has had three of his seven 100-yard rushing games gainst the Colts, and he's produced 200 or more all-purpose yards in three of five career games against Indianapolis.

With seven touchdowns, no player has scored more TDs against Indianapolis since 2006.

Drew didn't make it into the end zone Thursday, but he averaged 4.6 yards per carry and 10.1 yards per reception.

Five of Drew's touches - two runs and three passes - went for gains of 10 yards or more.

"Maurice Drew is a tough, tough football player," Dungy said. "He's a heck of a back."