Giuliana Rancic’s son Edward Duke has quickly become a constant, but she’ll have to leave her three-week-old bundle of joy with hubby Bill on Sunday when she covers for E!’s Live From The Red Carpet special at the Emmys in L.A.

She adds, “It’s going to be nice to be reunited with the Fashion Police crew – Kelly [Osbourne], George [Kotsiopoulos] and Joan [Rivers], but it’s going to be hard – that 24 hours away from the baby is still going to be pretty hard.”

Getting a baby break has been a welcome change for the reality star, who chronicled her struggle with breast cancer and infertility on her Style Network show Giuliana and Bill.

“I love maternity leave,” she says. “I’ve never taken off more than a few days in ten years, and so, to have all this time off to just bond with the family has been incredible.”

Catch Giuliana on E!’s Live From The Red Carpet special, which begins at 5 p.m. ET.

Giuliana is a spokesperson for "Do It For the Girls!" Day of Action, a P&G GIVE Hope initiative designed to motivate woman nationwide, via Facebook and Twitter Party #GiveHope, to conduct a breast self-exam and create an early detection plan. P&G will donate an uncapped amount to the National Breast Cancer Foundation.