The RIIB KO mutation rescues the obesity of Agouti mice in studies conducted by Traci Czyzyk and Ama Sikorski in the lab.

Two genetically lean mice weigh in on a scale with a genetically obese mouse.

Injection of AAV-CRE into the ventral medial hypothalamus of RIIbeta lox animals causes reexpression of RII in specific neurons. Linghai Yang is using this technique to determine what neurons require PKA-RIIbeta for regulation of energy balance and locomotor activity.

AGRP-cre dependent expression of HA-tagged ribosomes in the hypothalamus is being developed by Paul Amieux for gene array analysis of specific neurons.

Graduate student Katie Newhall measures a mouse's oxygen consumption as part of an effort to compare basal metabolic rate to body weight.