Experimental Pharmacology

We study the pharmacology of receptor and transporter targets using experimental techniques spanning from molecular pharmacology to in vivo testing in animals and human clinical trials.

Our main target classes are G protein-coupled receptors, ligand-gated ion channels and transporters of which the majority are related to central nervous system (CNS) disorders including chronic pain states, cognitive dysfunction and emotional disturbances.

Our main focus is to develop and use pharmacological tool compounds to delineate mechanisms of drug action, and investigate the mechanisms underlying CNS disorders and their potential treatment.

Our approach is highly interdisciplinary and builds on integration molecular, ex vivo and in vivo pharmacology with medicinal chemistry, as well as computational chemistry and clinical pharmacology with collaborators in academia, pharmaceutical companies and hospitals, both in Denmark and abroad.