When comparing Marionette Studio vs Moho 12, the Slant community recommends Moho 12 for most people. In the question“What are the best 2D skeletal animation tools?”Moho 12 is ranked 6th while Marionette Studio is ranked 9th. The most important reason people chose Moho 12 is:

Pros

Pro

Actively maintained

Marionette Studio team is actively involved in the development of this software. There is a changelog available and a public Trello board.

Pro

Cloud based solution

Projects and files can be stored in cloud and the is no need for creating backups.

Pro

Animation export

Animations can be exported as image packs and using some 3rd party tools can be imported and used in Unity.

Pro

Easy to use

Can be used by anyone - intuitive interface and short learning curve.

Pro

Web-based software

Easy to be accessed as no software needs to be download or installed on your computer.

Pro

Easy to use interface

Quicker to animate and use than other similar products.

Pro

Good community support

Lots of online forums, Facebook groups, YouTube videos, etc.

Pro

Cheaper than Toon Boom and Adobe Products

Cheaper than Toon Boom and Adobe Products. People often complain about the price hike, but the pro version does go on sale, and even the full priced version is less than other insdurty standards on the market.

Pro

It's better than any 2D animation software on the market for vector based animations

It beats Adobe Flash and Toon Boom at vector based animation. It has more features for 2D vector animations with it's integration with 3D mesh and bone rigs. Smart bone rigs create better animtions with less distortions then Toon Boom, and there are no bone rig animation options with Adobe Flash.

Cons

Con

No integration for major game development engines

There is no integration with major game engines such as Unity, Construct 2D, Unreal, Cocos 2dx, etc.

Con

Limited support for game engines

In most cases you'll have to export and edit sprite sheets. This will consume memory. Also, FBX file support is limited and not all features will run in Unity. Aside from Unity, there is no support for runtimes for video game engines. Also, many animation features such as vector integrated features will not export to Unity. Spriter, Spine, and Dragon Bones would be better options.