For one such investigation, a crewmate set up Neuromapping hardware to perform tests for Flight Day 90, conducting strapped in and free-floating body configurations. This experiment studies whether long missions can cause changes to brain structure and function, motor control and multitasking abilities, as well as how long it would take the brain and body to recover from the possible effects. Previous anecdotal evidence supplied by astronauts suggests that movement control and cognition can be affected in microgravity.

The crew also continued work with Veggie-03, watering the lettuce plants, documenting growth and selecting some for consumption. Veggie-03 supports the concept that for future long-duration space missions, a fresh food supply can be grown in space to supplement the crew while far from home.

On the ground, Expedition 55-56, consisting of Soyuz Commander Oleg Artemyev and NASA Flight Engineers Ricky Arnold and Drew Feustel, checked off more reviews of launch day and rendezvous procedures in anticipation of a March 21 liftoff from the Baikonur Cosmodrome in a Soyuz MS-08 spacecraft. They will join the crew already in orbit following a March 23 docking.