I was looking at a piece in the newspaper last week on some new research on women with post natal depression. There is a link between low levels of oxytocin during pregnancy and decreased ability to bond well with the baby and that has been shown as a factor in the ‘baby blues’. However, the suggestion that women who are likely to be more prone to this should be given oxytocin during their pregnancy as a ‘preventive’ doesn’t make much sense to me. If a woman is overdue then hospitals give oxytocin to start labour so that might give a women pause for thought over taking it during a pregnancy don’t you think? The risk of starting labour prematurely is a real one, and there is no need to take such action when there are alternatives available.

Previous research has confirmed that giving the hormone natural progesterone given during pregnancy, and afterwards, can help control post natal depression and also prevent miscarriage in the first trimester. If you know someone who is concerned about this then there are two excellent articles on dealing with post natal depression by Dr Tony Coope at http://www.bio-hormone-health.com/2010/04/16/hormones-and-the-baby-blues-part-1/

Premature Birth Risk Reduced by Half:
A new study published in the journal Ultrasound in Obstetrics and Gynecology has found that natural progesterone given to certain groups of pregnant women effectively reduced premature birth rates by 50 percent. Doctors working with natural hormones have for many years recommended natural progesterone to help women both before and during pregnancy and now this new study has identified pregnant women with a condition known as short cervix as being specifically lacking in progesterone.

Progesterone is an essential hormone released by the corpus luteum that stimulates the uterus to prepare for pregnancy, and provides optimum conditions in the body that are necessary for the furtherance of the pregnancy and the development of healthy babies.

For the study, Dr. Sonia S. Hassan and her team from the National Institutes of Health (NIH) assigned 458 pregnant women to either receive a once-daily dose of vaginal progesterone, or a once-daily dose of a placebo gel, during their second and third trimesters. While 16 percent of those in the placebo group gave birth before the 33rd week of pregnancy, only 8.9 percent in the progesterone group gave birth early.

Besides reducing the overall rate of preterm births, the progesterone also demonstrably reduced the rate of respiratory distress syndrome (RDS), a breathing disorder linked to early births. Not only did the women themselves experience less cases of RDS as a result of taking progesterone, but so did their children. Infants whose mothers did not receive progesterone during their pregnancies were nearly three times more likely to develop RDS than children from mothers who took the hormone.

Dr. Roberto Romero, chief of the Perinatology Research Branch of NIH, said “The study … offers hope to women, families and children. Worldwide, more than 12 million premature babies — 500,000 of them in this country — are born each year, and the results are often tragic. Our clinical study clearly shows that it is possible to identify women at risk and reduce the rate of preterm delivery by nearly half, simply by treating women who have a short cervix with a natural hormone — progesterone.”

Although this study was done using progesterone gel, progesterone cream is a highly effective and rapid delivery method, as well as being cost effective, and I would like to see another study done using it.

Wellsprings Serenity is a premium natural progesterone cream for conditions associated with hormone imbalance, including osteoporosis and menopause related symptoms.

Recommended by John Lee MD, Serenity cream has been helping women since 1995, you can learn more about Wellsprings Serenity and natural progesterone with free booklets on hormone balance and osteoporosis written by AnnA Rushton and Dame Dr Shirley Bond by visiting

Throughout our lives our bones continue to break down, and be replaced with new material as part of our body’s natural cycle of growth. However, when whole bones need to be replaced after tumours, or accidents, then there has so far been no way to successfully grow replacement bones. It happened in fiction with J K Rowling’s description of Skele-Gro which magically re-grows bones in around 8 to 12 hours and is a very painful process. Many women with osteoporosis find that using a natural bone growth promoter like natural progesterone may take longer but certainly isn’t painful!

Not sure if the scientists at Imperial College London had this in mind, but it seems that there is a worldwide interest in producing bone-like materials derived from stem cells with stem cell technology. The research results were recently published in the journal Nature Materials and it is hoped will be able to be implanted into patients who have damaged or fractured bones, or who have had parts of diseased bones removed. The idea is that, ultimately, these bone-like materials could be inserted into cavities so that real bone could meld with it and repair the bone.

It is currently possible to grow small ‘nodules’ of what appear to be bone-like material in the laboratory from different types of bone cells and stem cells. It is these different types of material that the scientists from Imperial College London have been comparing and they have discovered significant differences between the quality of the bone-like material that these can form.

For example, they found that materials grown from bone cells from mouse skull and mouse bone marrow stem cells successfully mimicked many of the hallmarks of real bone, which include stiffness. However, they found that the material grown from mouse embryonic stem cells was much less stiff and less complex in its mineral composition when compared to the other materials.

So what we have here is a good starting point as Professor Molly Stevens, from the Institute of Biomedical Engineering at Imperial College London, says: “Many patients who have had bone removed because of tumours or accidents live in real pain. By repairing bone defect sites in the body with bone-like material that best mimics the properties of their real bone we could improve their lives immeasurably. It brings us one step closer to developing materials that will have the highest chance of success when implanted into patients.”

When I was running the Natural Progesterone Advisory Service I would hear many reports of the cream being used for other purposes than the recommended use for osteoporosis or hormone management. Most of these claims were anecdotal, and interesting but not verifiable. Over the years there has been research on the benefits of natural progesterone, but the most powerful advocates are still its users.

I was always particularly interested in its use for men, and the late Dr John Lee – the pioneer of natural progesterone usage – told me he often prescribed it for men with osteoporosis as, although there had been no research done, his patients showed consistently good results and higher bone density.

A similar situation has now come to my attention, with men using natural progesterone cream as part of their own treatment/self help programme for prostate cancer. Trevor Taylor runs Wellspring, a company that imports natural progesterone, and I am passing on information he gave me and which I think will be of interest to anyone with a family member at risk. I stress this is an anecdotal story, not medically verified, and I have let Trevor tell it in his own words:

I want to tell you about the experiences of a personal friend who was diagnosed with prostate cancer in 2007. He has had a poor medical history and is 70 years old and in 1996 was diagnosed with cancer of the oesophagus; which was operated on in 1996, 2000 and 2003. In 2003 he also had a double hip replacement operation. He then learned of his prostate cancer diagnosis in 2007.

Over the years we have had several women customers who have recounted to us how natural progesterone had helped their husbands or partners who were suffering from prostate cancer. I of course was aware of this but was reticent to publicise these reports, but when my friend told me of his diagnosis I asked him if he would like to try it as well as his prescribed treatment, on the basis that it would do him no harm and might well help.

He was first diagnosed in October 2007 and eight sample biopsies showed a PSA level of over 4000. The ideal is less than one. His treatment is 3 monthly Zoladex injections and he used natural progesterone cream daily. In January 2008 his PSA level was checked and had dropped from 4,000 to 100. At the next check in April 2008 it had dropped from 100 to 20. The next check in August 2008 showed a drop from 20 to 6. Checks and treatment have been extended to 4 monthly and I am pleased to say that my friend looks in good health, is very active; married in August 2008, and is thoroughly enjoying life.

Now Trevor Taylor does not claim that this remarkable drop in PSA levels from over 4000 to just 6 in just eleven months is due entirely or in part to his friend’s using natural progesterone, but it is certainly food for thought. If you want to know more about using natural progesterone you can contact Wellsprings for a free booklet and more information on 01481 233370 or via their website at www.progesterone.co.uk

No matter what your age, your hair reflects your state of health and particularly as we get older it is more prone to weakness and thinning. You don’t have to accept poor or lacklustre hair as a given, because there are plenty of things you can do naturally to help improve its condition. These suggestions might help:

Thinning hair: The hormone natural progesterone has been used by several trichologists to help people with thinning hair, in particular Ailsa Bosworth of Hair Tomorrow has had good success. The ‘recipe’ for healthy hair is to have a good intake of iron, zinc, vitamin C and B vitamins. All of those can be got from a good healthy diet but if you have a serious hair loss problem then it will be worth while taking them as supplements. A natural way to stimulate hair growth is to go out in the countryside and pick some nettles or get dried nettle from any good herbalist, or online from people like Neal’s Yard. This old-established method is easy to follow, because instead of using shampoo, you take a handful of loose nettle tea and boil in water. Strain the tea, let it cool and then use it to ‘wash’ your hair.

If you can’t bear not to use shampoo, then please pick one that is organic, mild, natural and PEG free. That excludes most commercial, major brand shampoos no matter how ‘herbal’ or natural they claim to be. Not sure what to look for? Avoid these:

Always read the label, and if you have trouble finding such a shampoo locally, then Simply Nature have a very effective natural one and you will find it on their website at www.simply-nature.co.uk. Your scalp matters if we are not happy with your hair, it’s tempting to hide it away under a hat or scarf, but please don’t. Your scalp has to be healthy to allow new hair growth to come through, and in order to do that you need to keep your pores and hair follicles free of dead skin cells. One of the best ways to do that is to massage your scalp every night before you go to bed.

Here’s a great two fold process: first using a metal comb tap all over your head with it for about a minute. It has to be metal, not plastic, because tapping with metal will create tiny electromagnetic currents on the scalp that stimulate the cells in the hair follicles. Next, you massage your scalp gently with a few drops of jojoba oil. It will naturally and gently help cleanse your scalp and contains lots of great hair nutrients like Vitamins C and B and the hair health mineral Zinc.

Over the years of working with natural progesterone for osteoporosis, I was often asked about whether men also suffered from this painful bone condition – and the answer is a resounding yes. Because you don’t get any early warning symptoms with osteoporosis, it is vital for men to keep track of their health. I talked with a man in his 30′s who played rugby every Saturday and kept getting more frequent bone breaks than average. When he had a bone scan, he had advanced osteoporosis and all the fractures had been his ‘early warning’ signs.

Certainly men do benefit from taking natural progesterone for osteoporosis, but there now seems to be another factor, certainly in older men. Getting plenty of vitamin C from foods and supplements seems to boost bone strength in the over 70′s, according to research at Tufts University, Massachusetts, USA. They found that men whose had the highest intake of vitamin C intake also had the least bone loss in the hip. On an average dose of 314mg those didn’t lose bone density in the hip- even when their calcium intake was low – but men who got the least vitamin C of only 106 mg per day lost 5.6 percent of their bone over the four years.

Sadly the same effects were not seen in the women in the study, but it’s a good reason for getting at least 500mg of C a day to help protect bone health.

Some years ago I set up the Natural Progesterone Information Service to provide women with the latest news on natural hormones rather than synthetic ones such as HRT. One of the things that John Lee talked a lot about all those years ago was how in his opinion the biphosphonate drugs given for osteoporosis were actually weakening the bone rather than helping to build it. He had seen great results with women using natural progesterone to build bone density, though the medical profession did not accept that progesterone could work more effectively than the drugs. Now after all these years, more questions have emerged about whether long-term use of bone-building drugs for osteoporosis may actually lead to weaker bones in a small number of people who use them. Case reports show an unusual fracture pattern in people who have used bone-building drugs, the biphosphonates, for five years or more.

If you are taking such drugs please ensure you are also having regular bone scans to check your progess and it would be worth looking at your diet and natural supplements that can help build bone such as horsetail and silica. If you would like information on natural progesterone for osteoporosis and HRT replacement (I no longer have any connection with the service since I gave up running it) you can obtain a booklet from the Natural Progesterone Information Service, tel: 07000 784849 or visit their website at www.npis.info.
Wellspring Trading in Guernsey also have an excellent free booklet on natural progesterone cream which is written by my good friend and colleague, Dr Shirley Bond – a private GP who specialises in hormone therapy for women. Wellspring’s telephone number is – 01481 233 370.

I am very familiar with this natural hormone being used to treat osteoporosis and alleviate menopause symptoms, but Guomin Xiao, M.D., of Zhejiang University, has been doing a trial on treating head injury patients with injections of progesterone.

What was found was that less-severely brain-injured patients had almost a 50 per cent better chance of survival and better function after six months of treatment. Progesterone appeared to have little or no other effect during the acute phase but the main effect was seen during the recovery period after the patient had been discharged.

Although interesting, this was only a small study of 153 patients and further research is needed. However, certainly one of the benefits of progesterone as I have seen it used is to help alleviate depression, so it makes sense to see it extended to other brain function issues. Other medical research has previously found that the hormone aids in neuronal development and protects brain function in animal experiments.

Please Note: Natural progesterone is not available in the UK without a prescription as it is regulated as a natural medicine, although it is perfectly legal to buy it outside the UK and import it for your own use. Anyone wanting further information on how to obtain natural progesterone can contact us.

It was widely reported in March 2008 that breast cancer survivors, who were afterwards treated with HRT, had a more than two-fold increased risk of a recurrence. According to long-term follow-up data from a randomised clinical trial, after five years women with previous breast cancer had a recurrence rate of 22.2% compared with 8% in women who received no hormone therapy. The study was undertaken at King’s College London, and scary though it is, I would suggest any woman with follow up care for breast cancer examines her options carefully.

This study does not, sadly, stand alone as more recently, data from the Women’s Health Initiative and the Million Women Study provided additional compelling evidence of an increased risk of breast cancer among HRT users, according to the King’s College researchers and authors of the above study.

It is the oestrogen in HRT that is the problem, as it causes proliferation of the cells, so investigate alternatives such as natural progesterone. An excellent book on this is the one by the late John Lee, MD called ‘What Your Doctor May Not Tell You About Breast Cancer’, and the straightforward book I co-wrote with Dr Shirley Bond on the applications of the hormone and called simply ‘Natural Progesterone’ and which is available from the website at www.catalystonline.co.uk

As the woman who set up the Natural Progesterone Information Service many years ago to alert women to the benefits of progesterone for osteoporosis I used to talk to lots of women who were on drug medication for their condition. I, and others, were concerned about the long-term effects of these drugs and just how effective they actually were.

Now according to a report in the January 19 2008 issue of the British Medical Journal it appears that pharmaceutical companies exaggerate the benefits and downplay the risks of prescribing osteoporosis drugs for women whose bones appear to be slightly weakened. This condition (osteopenia) is not full blown osteoporosis but the pre-stage and this new report says that pharmaceutical companies are pushing doctors to prescribe osteoporosis drugs for this group of women.

The problem with this is that women with osteopenia have such a low risk of experiencing fractures that taking osteoporosis drugs would provide almost no benefit. The study co-author Dr. Pablo Alonso-Coello, a family physician at Hospital Sant-Pau in Barcelona, contends that four studies that found benefits to giving osteoporosis drugs to women with osteopenia exaggerated those benefits.

Statistics can be tricky things, but Dr. Alonso-Coello gives the following example:

** The absolute risk of a woman with osteoporosis having a fracture in a given year might be 10 percent so the effect of an osteoporosis drug is to lower that risk by half, so the absolute benefit is a 5 percent reduction.

** But in women with pre-osteoporosis (osteopenia), the risk of fracture is very low, say 1 percent a year, so if you lower that by half, you go down to 0.5 percent absolute reduction.

One study cited in Dr. Alonso-Coello’s paper claimed a 75% relative reduction in risk of fracture. The absolute risk reduction was 0.9 percent, which, from a statistical perspective, means that up to 270 women with pre-osteoporosis would have to take osteoporosis drugs for three years to avoid a single fracture. Risks of Taking Osteoporosis Drugs These drugs are not risk-free and the pioneering work of the late Dr John Lee alerted many women to the potential hazard to their health they were risking by taking them. Just this month, researchers at the University of British Columbia and McGill University issued a warning on a class of osteoporosis drugs (bisphosphonates) taken by millions of women around the world that can lead to bone necrosis, a painful and disfiguring condition. The U.S. Food and Drug Administration also issued an alert on bisphosphonates, including alendronate and risedronate, warning that these medications can cause severe bone pain.