Title (fr)

Publication

Application

Priority

US 9911268 W 19990521

US 8649798 P 19980522

Abstract (en)

[origin: WO9961579A2] An important advance in the battle against drug resistance by elucidating the domains of MarA which are critical in mediating its function. Accordingly, MarA family protein helix-turn-helix domains, mutant MarA family protein helix-turn-helix domains and methods of their use, for example, in screening assays to identify compounds which are useful as antiinfective agents and in screening assays to identify loci which are involved in mediating antibiotic resistance are described.