Anyone else been diagnosed as having the MTHFR mutation? I recently learned I have one copy of this gene mutation. My OB recommended baby aspirin as the treatment, but I have read mixed things on what the best treatment is. If you have this, what did your doctor recommend as treatment? (I am not currently pregnant, BTW.)

I've researched a lot about this. Did you know 40% of the population has one copy (or hetero) MTHFR?
I'm Homo (two copies) MTHFR but I also have Factor V, Pai-1 and Hashimoto's with extremely high anti-thyroid antibodies.
After close to three years of TTC and several early losses I finally left my clomid/IUI happy RE and found an OBGYN who would let me 'try' a few rounds of lovenox. (The RE would only let me try baby aspirin until confirmed pregnancy but I knew my issue was w/ implantation because I couldn't carry past 4 1/2-5 weeks, we never made it to 'heart beat')
On our 4th lovenox & femara (I O really late on my own without meds) cycle we got this sticky bfp.
Typically baby aspirin is the treatment if you only have one copy but if you feel in your heart you need more then I would push for it, even find a different dr if you need to. Pray on it, God will guide you like he did for me, on the best treatment.
Here is a website of ladies ttc w/ lovenox http://community.babycenter.com/groups/ ... enox_groupAnd here is a yahoo group for women TTC with immunology issues (MTHFR) would fall in that group, this site is cram packed full of info and led me on my search for the right treatment: http://health.groups.yahoo.com/group/immunologysupport/Be proactive, learn every thing you can to arm yourself with the right questions to ask your dr. Don't just go along w/ what they say, you have to almost dr. yourself when it comes to this.
Good luck, if I can help PM me

yes, happygolucky is correct, one copy of the mutated gene is pretty common. I am also + for one copy of MTHFR but also have Factor V which makes me alittle more high risk. My RE put me on baby aspirin and when I confirmed a pregnancy, I went on Lovenox at about 9 weeks and switched to Heparin at about 37 weeks pg.

I think your OBs suggestion to take baby aspirin regularly is a good one. Good luck and lots of babydust to you!

I have 2 copies of the gene and was put on baby aspirin until the day I delivered, lovenox injects. until 28 weeks and was on a heavy vitamin therapy... part of the mthfr gene is that it doesnt allow you to absorb folic acid properly or B vitamins. I was also told to start taking large amounts of folic acid and b vitamins. Pm me if you want to know exactly what it is I took (I can't remember off the top of my head and I would need to lookn it up...) Good luck!

I have two copies of the gene as well. I'm taking extra folic acid because of this. I also have factor V leiden. Spoke to a hemo doctor who said a lot of people have factor v and he wasnt worried about that. But i also have lupus anticolaguent and positive ANA's. I'm on lovenox now. I'll be high risk. Now I"m seeing and RE since I'm only 4 weeks and 4 days but I'll be seeing a high risk doctor then. Had many miscarriages and I hope this will finally be it for me and a stick one.

I have one copy of the gene and throughout this pregnancy, I have been on 5 mg of folic acid a day. It is something that my doctors have recommended I continue even after I am pregnant, in order to prevent deep vein clots in the long term.

Addressing the folic acid - there is a prescription prenatal out called Neevo DHA that has a special kind of folic acid that is supposed to be really great for those with MTHFR (something about the type it is and it bypassing any issues with absorption), you might want to ask for a script - I'm on it "just in case" because of all of my losses.

I have two copies and its recommended I take baby asprin and high doses of folic acid and vitamin b for my whole life to avoid blood clots, strokes, etc. I take Folbee Plus for this. I never had to do any other blood thinners. I had recurring miscarriages also, even after starting these meds. They found my progesterone does not raise like it should so I was also on progesterone to hold off AF until 14 days after ovulation. But now I have my magic potion because I am pg with #2.

I just found out I also have one copy of this gene (C). I am on my first pregnancy ever and exactly 6 weeks along. I had an ultrasound at 5w2d and all seemed to be progressing normally. I was told to take an EXTRA 200 mcg of B6, 500 mcg of B12 and 4mg of folic acid in addition to my prenatal. My doctor doesn't sound too worried and reassured me there is very little proof that this is directly correlated with miscarriages or birth defects, but I am worried that I have not been providing enough folic acid to my baby so far during this critical time. Is it possible that it has caused damage not having taken the extra folic acid, such as neural tube defects? (BTW my mom also recently found out she has this gene and had me and twins over thirty years ago and we were all perfectly healthy.) Please chime in ladies and let me know what you think. Thank you!