Return to the Tower (High Chaos)

Playing through Return to the Tower on High Chaos is a task about sniping and being thorough. You can kill many in open combat, except when you face a Tallboy, an indestructible Watchtower, and about 10,000 Red Shirt City Guardsmen with Overseer Organgrinder and Wolfhound back-up.

You should have a enough runes (accumulated from missions and the Hounds Pit bonuses) to pick some nice powers (like extra Vitality) but also Wind Blast (which substitutes for Grenades and Spring Razors once upgraded to lethal speed) and Adrenaline.

With the loot you should be getting from slaying foes and exploring, you should be able to upgrade Corvo's pistol, Crossbow, and various bomb devices.

Bring the body count up using drop assassinations, and resort to stealth to gather enemies to a large group for Spring Razors or Grenades to be effective.

With the carnage you're causing on High Chaos, you will want to thoroughly explore all areas and choices for coin. You will need the cash to spend on Sokolov Elixirs and upgrades for Corvo's Crossbow and Pistol.