General Information on Viramune XR

Viramune XR, with the active ingredient Nevirapine, is prescribed for the treatment of HIV infections. This drug falls under a category of drugs known as reverse transcriptase inhibitors. You can buy Viramune XR online from a certified and reputable online prescription service, but you must note that it cannot cure HIV or AIDS.

Side effects of Viramune XR

You should not buy Viramune XR if you are hypersensitive to any of its constituents. This drug can cause life-threatening side effects in some cases. Your doctor may ask you to undergo certain tests before and during treatment to ensure that you do not experience any fatal side effects.

The use of Viramune XR in certain conditions may not be recommended, or patients may require special monitoring or dosage adjustments. Inform your doctor if you have a kidney disease, liver disease or malfunction, or skin problems.

In some patients, Viramune XR has been reported to cause fatal toxicity of the liver. Watch out for these signs of liver damage: loss of appetite, nausea, dark urine, low fever, dark or black stools, skin rash, or yellowing of the eyes or skin. If you experience any of these, consult your doctor immediately.

In some patients, Viramune XR has been reported to cause severe skin reactions. Consult your doctor if you experience any of the following symptoms: swelling in the tongue or face, skin pain, fever, sore throat, or burning in the eyes.

Mild side effects associated with Viramune XR may include:

Tiredness

Headache

Diarrhea, vomiting, stomach pain, or nausea

Muscle pain

Although this drug is considered safe to be taken during pregnancy, you should consult your doctor before you buy Viramune XR. You should not breastfeed if you are HIV positive as the virus may enter your baby’s body through breast milk.

Dosage of Viramune XR

The recommended dosage for adult patients is Viramune XR 200 mg daily for the first 2 weeks. After this period, the dosage should be increased to 200 mg twice daily.

Pediatric patients who are 15 days or older should be given 150 mg/m² for the first 2 weeks. After the first 14 days, the dosage should be doubled to 150 mg/m² two times per day. The maximum daily dosage is Viramune XR 400 mg. A daily dose in excess of 400 mg should not be administered.

Interactions

You should not take the following drugs if you are using Viramune XR:

St. John’s wort

Efavirenz

Ketoconazole

Atazanavir

Itraconazole

Rifampin

The following drugs are expected to interact with Viramune XR:

Antifungal medicines such as voriconazole or fluconazole

Blood thinners

Antibiotics

Maraviroc

Other HIV drugs such as nelfinavir, darunavir, ritonavir, saquinavir, or indinavir

Anti-seizure medicines

Certain antibiotics such as rifabutin or clarithromycin

Methadone

Blood pressure or heart medicines such as ergonovine, ergotamine, methylergonovine, or dihydroergotamine

Drugs that are not listed above may also interact with this HIV medication. Your doctor will know about this, so inform him/her about all other medicines that you are taking. If you are using any drugs that have a potential to interact with Viramune XR, your doctor may reduces its dosage or ask you to stop taking that drug.

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What is a "Generic" medication/drug?

Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:

Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)

Dosage (e.g. 10 mg of the active ingredient)

Safety (e.g. same or similar side effects, drug interactions)

Strength

Quality

Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)

Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)

What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.

What differences are there between generic and brand?

While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:

Color

Shape

Size

Cost

Appearance (e.g. the scoring or markings)

The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.

Why do generics cost less than the brand name equivalents?

When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.

The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.

How are Generic drugs tested to ensure quality and efficacy?

The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.