STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RPS16

40S ribosomal protein S16 (143 aa)

Predicted Functional Partners:

RPL16A

60S ribosomal protein L16 (200 aa)

0.999

XP_446276.1

40S ribosomal protein S2 (253 aa)

0.999

XP_446019.1

40S ribosomal protein S15 (143 aa)

0.999

XP_448200.1

40S ribosomal protein S3 (247 aa)

0.999

RPS11B

40S ribosomal protein S11 (156 aa)

0.999

XP_446818.1

40S ribosomal protein S5 (225 aa)

0.999

RPS0

40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits (251 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

RPL16A

RPS0

XP_448152.1

XP_449470.1

60S ribosomal protein L16

40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits

0.994

RPL16A

RPS11B

XP_448152.1

XP_448726.1

60S ribosomal protein L16

40S ribosomal protein S11

0.998

RPL16A

RPS16

XP_448152.1

XP_447288.1

60S ribosomal protein L16

40S ribosomal protein S16

0.999

RPL16A

RPS29

XP_448152.1

XP_445451.1

60S ribosomal protein L16

40S ribosomal protein S29

0.986

RPL16A

XP_445776.1

XP_448152.1

XP_445776.1

60S ribosomal protein L16

40S ribosomal protein S19

0.990

RPL16A

XP_446019.1

XP_448152.1

XP_446019.1

60S ribosomal protein L16

40S ribosomal protein S15

0.994

RPL16A

XP_446276.1

XP_448152.1

XP_446276.1

60S ribosomal protein L16

40S ribosomal protein S2

0.994

RPL16A

XP_446818.1

XP_448152.1

XP_446818.1

60S ribosomal protein L16

40S ribosomal protein S5

0.997

RPL16A

XP_448200.1

XP_448152.1

XP_448200.1

60S ribosomal protein L16

40S ribosomal protein S3

0.998

RPL16A

XP_448361.1

XP_448152.1

XP_448361.1

60S ribosomal protein L16

40S ribosomal protein S20

0.993

RPS0

RPL16A

XP_449470.1

XP_448152.1

40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits

60S ribosomal protein L16

0.994

RPS0

RPS11B

XP_449470.1

XP_448726.1

40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits

40S ribosomal protein S11

0.998

RPS0

RPS16

XP_449470.1

XP_447288.1

40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits

40S ribosomal protein S16

0.999

RPS0

RPS29

XP_449470.1

XP_445451.1

40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits

40S ribosomal protein S29

0.999

RPS0

XP_445776.1

XP_449470.1

XP_445776.1

40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits

40S ribosomal protein S19

0.998

RPS0

XP_446019.1

XP_449470.1

XP_446019.1

40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits

40S ribosomal protein S15

0.998

RPS0

XP_446276.1

XP_449470.1

XP_446276.1

40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits

40S ribosomal protein S2

0.998

RPS0

XP_446818.1

XP_449470.1

XP_446818.1

40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits

40S ribosomal protein S5

0.998

RPS0

XP_448200.1

XP_449470.1

XP_448200.1

40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits

40S ribosomal protein S3

0.999

RPS0

XP_448361.1

XP_449470.1

XP_448361.1

40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits

40S ribosomal protein S20

0.998

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: