When four lifelong friends travel to New Orleans for the annual Essence Festival, sisterhoods are rekindled, wild sides are rediscovered, and there's enough dancing, drinking, brawling, and romancing to make the Big Easy blush.

Two former backup soul singers, Louis and Floyd, have not spoken to each other in 20 years, and reluctantly agree to travel across the country together to a reunion concert to honor their recently-deceased lead singer. Cleo, a beautiful young woman who is believed to be Floyd's daughter, accompanies them as a new singer.