On a day the Seahawks settled for four field goals and had a safety, Wilson watched as Andrew Luck again rallied the Colts late and led Indy to a 34-28 victory.

"We had a lot of situations today that we could have controlled a little bit better. For whatever reason, we didn't make those," Wilson said. "We've got to find a way to eliminate that situation. When we have a chance to separate the game, we need to make sure that we do that."

The Seahawks (4-1) certainly had chances, they just couldn't convert as they suffered their first loss of the season.

Despite holding the Colts to 317 yards of offense, rushing for 218 yards and keeping the ball nearly twice as long as Indy (4-1) through the first three quarters, Seattle couldn't put this one away because of mistakes.

The Seahawks finished 2 of 12 on third downs, star cornerback Richard Sherman was called for pass interference on third-and-10 during the Colts' go-ahead drive and they couldn't recover a blocked punt in the end zone inbounds.

Seattle had won nine straight regular-season games since last losing Nov. 25 at Miami.

"We moved the ball really well. Had a lot of yards and all that. Russell was very resourceful, Marshawn was on today. The guys up front did the best they could," coach Pete Carroll said. "We really struggled on third down. That was the difference. Those turned into field goals."

And against Luck, that's always trouble.

He has led the Colts to nine fourth-quarter wins in 21 career games. Luck finished 16 of 29 for 229 yards with two touchdowns. Donald Brown scored on a 3-yard TD run with 8:55 to play, to give Indy the lead for the final time of the day.

"This is the most resilient team that I've ever been around," coach Chuck Pagano said. "They've got more grit than anybody, any team I've been around."

Indy has rebounded from its only loss with three straight wins, including victories over NFC powers San Francisco and Seattle. Now they have sole possession of the AFC South lead for the first time in the post-Peyton Manning era, too.

And all this came on a wacky day.

Both teams scored off a blocked kick. The Seahawks ran for 218 yards, averaged 6.4 yards per carry, had better field position and ran more than three dozen plays in Colts territory as they played keep away through the first three quarters.

None of it mattered to Luck. He still found a way to win.

On the decisive drive, he took advantage of a pass interference call against Sherman, got another break when Pagano won a challenge on a third-down spot that turned fourth down into a first down.

After consuming nearly seven minutes, he gave the ball to Brown, who squirted through the middle for the go-ahead score.

Luck then hooked up with his favorite receiver Reggie Wayne on a 2-point conversion pass and took nearly five more minutes off the clock to set up Adam Vinatieri for a game-sealing 49-yard field goal.

"A win is a win, if it was ugly, if it was great," Luck said. "To come back, you hold on for dear life, but a chance to beat a good team in front of our home fans, to get back on track at home, we take a lot of pride in that."

Wilson went 15 of 31 for 210 yards with two TDs before throwing an interception on the Seahawks' final play. He ran 13 times for 102 yards, Lynch ran 17 times for 102 yards, and the defense limited Indy to just 317 yards of offense, 120 of that coming in the fourth quarter.

The Seahawks also blocked a punt that bounced into the end zone and was recovered out of bounds for a safety.

After Seattle took a 12-0 lead, Luck got Indy back into the game with a 73-yard TD pass to T.Y. Hilton, and the Colts took the lead when Delano Howell returned a blocked field goal 61 yards for a score.

The Seahawks regained the lead 19-17 at halftime and appeared to be in good shape after two quick field goals in the third quarter.

But after taking a 25-17 lead, Luck rallied the Colts again — and this time, he made sure Wilson & Co. got to watch it all from the sideline.

"I don't think, anybody's built better to win these close games, especially down the stretch, especially in the fourth quarter than this team," Pagano said.

Notes: Hilton caught five passes for a career-high 140 yards and two scores. ... Colts defensive end Robert Mathis was credited with his 100th career sack when he forced a fumble at the end of the first half. He added another in the second half. .... Reggie Wayne caught six passes, leaving him four short of the 1,000-yard mark. ... Seattle was missing three of its starting offensive linemen for the second straight game. ... The two TD passes by Luck matched the total Seattle had allowed in its first four games.