With players dedicated to making the time to post at least once a day. I've wanted to play a 3.5 Paladin using the E6 ruleset for a long time now. The setting doesn't much matter, could be anything an E6 version of a classical setting like Wilderlands of High Fantasy or Eberron doing typical adventures, a party of adventurers who activate an ancient artifact and become stranded in some campy plane of lust, a High seas or Airship pirate/marine adventure, the party are all members of some prince's harem and he's taking them with him on his trial to prove himself more worthy to inherit the throne than his many many siblings who are trying to finish their own trials before he does, whatever the gm feels like running, there's never a shortage of players interested, so keeping the gm motivated is the most important thing.