The three novellas would then be published as a book, together with an essay by the scientist who created the planet. This formula, which Pratt called a "Twayne Triplet", had already resulted in the book The Petrified Planet in 1952.

The scenario created was that of a binary star system in the globular cluster, Messier 13, with an Earthlike planet called Troas (or more informally, "Junior") located at one of the system's Lagrangian points. An earlier expedition to Troas for colonization had suffered some mysterious disaster, and a second expedition is being sent to find out if "Junior" was suitable for colonization, and to find out what happened to the first expedition.

Asimov finished his short story, and then Anderson finished a story called "Question and Answer", but Kidd (or James Blish) never completed the third story. The proposed book was never printed. Asimov anticipated that just such a thing might happen, and he arranged that he held the first serial rights for his story. He sold "Sucker Bait" to Astounding Magazine, where it appeared just a few months before "Question and Answer".

The story concerns the starship George G. Grundy, or Triple G., which has been chartered by the "Confederacy of Worlds" to investigate "Junior". The only nonscientist among the passengers of the Triple G. is 20-year-old Mark Annuncio of the "Mnemonic Service", who has been trained from the age of five to memorize and correlate vast amounts of information.

Over a century earlier, an attempt to colonize Junior had failed. After nearly two years on the planet, all 1,337 colonists had died for reasons unknown. The scientists of the Triple G. and Annuncio have the mission to find out what killed them. For the first two weeks after landing, everyone remains aboard while the scientists take readings. After Rodriguez, the expedition's microbiologist, declares that the local life forms are noninfectious, a handful of scientists, plus Annuncio, travel to the original site of the colony.

Relations between the scientists and Annuncio deteriorate rapidly. The Mnemonics are loners by nature, and their training makes them even more so. The scientists, on the other hand, as specialists, tend to be contemptuous of a professional generalist like Annuncio. When Annuncio asks Rodriguez to explain how he came to a conclusion, the microbiologist regards the request as an affront to his professional reputation, and refuses to answer. The other scientists manage to offend Annuncio in various ways.

When Annuncio finally realizes that the abnormally high concentration of beryllium in the soil and plants of Junior was what killed the colonists, and that they all have to leave immediately, he does not trust the scientists to deal with it. He returns to the ship and persuades the crew to mutiny and take the ship off from the planet. The captain is barely able to convince the crew to stop at the colony site to pick up the scientists. When Annuncio is put on trial for fomenting the mutiny, he explains his actions, is acquitted, and the ship returns to the Earth to seek medical treatment for its crew for beryllium poisoning.

Like other short stories by Asimov such as The Dead Past and Profession, the theme of Sucker Bait is the peril of scientific overspecialization. Only Annuncio, the professional generalist, can make the connections between seemingly unrelated facts that solves the mystery of the deaths of the original colonists, and he saves the crew and passengers of the Triple G. from sharing that fate. Asimov would soon begin to practice what he preached, making himself into a professional generalist by writing popular science books on a number of different fields, as well as The Intelligent Man's Guide to Science, a general overview of science as a whole.

Some "80,000 worlds" are mentioned as having been colonized by that period of time, and it is perhaps an interesting coincidence[according to whom?] that the Spacer world of Aurora—completely unconnected to the Foundation Universe at the time Asimov wrote the story—is mentioned. This points to Sucker Bait having taken place during a period in which Aurora itself was still populated and known to the galaxy at large, and some as-yet-unrevealed time prior to the Mycogenian relocation to Trantor. However, it is also possible the novella occurs in a separate continuity, and the similarity of names is purely coincidental.

This novella was stated by Asimov (in 1955) [3] to have been set in his Foundation Universe, although some slight inconsistencies exist with the political status and physical condition of the Earth by the time frame of the tale—with no mention being made of the Earth's ever-increasing radioactivity (though this was retconned to be a very, very gradual process, and not the result of a nuclear war c. the 10th millennium), and the Earth still appears to be the center of the human race in general. This, however, was an early version of the timeline, inconsistent with Asimov's "Robot" tales.

Mark Annuncio's memory and mental abilities and behavior is similar to that displayed by some people with autism spectrum disorder, particularly Asperger syndrome.

At one point, a scientist states that a computer cannot do what the Mnemonic Service does, since even if there is a computer that knows all the required data, no one will know to ask the right question. A similar theme is present in the short story Jokester, which it is stated that such people (so called Grand Masters), capable of finding the right questions to ask the all-knowing Multivac do exist, but are extremely rare, only born about once a decade.

The cover for the issue of Astounding magazine in which this novella appeared is notable for its chemistry-based wordplay. That cover shows a group of people gathered before an promotion-of-emigration poster reading "Be on Troas." Though this is apparently an invitation to emigrate, it is also a slight give-away of the story's solution: "Be" is the chemical symbol for beryllium.