My biopsy report reveal I have a yeast infection on both lips.
I have peeling lips for 10 years now.
My doctor is prescribing me Diflucan pills for 2 weeks starting today.
I'm hoping once the yeast is gone, the lips will permanetly heal up.

Do you have the same condition as us :
- white stuff every morning when you wake up (like the photos posted by me (alesiom11))
- always the same area that peels
- Continous peeling process since years, without pause.

Thank you and good luck for your treatment. Could you please make an update in few weeks on this forum ?

Update lip biopsy result show yeast infection.
I been taken Diflucan for 14 days now to treat the yeast infection for my peeling lips. I also apply corticoid ointment on my lips.
I don't see any improvements since I been on my medication.
My lips are still scabbing up.
I still have white stuff sticking on my teeth.
My lips still washes and peels off.
I don't know what to do, but keep hoping my lips will eventually heal up.

hello, I would like to suggest a way to get rid of your lip problem, I don't know if it will stay away so you may have to keep using it - but it has worked for a frined of mine with psoriasis, and then with me when I got something that looked like what you have, except above my belly.

There is a product called Miracle II, I suggest u buy the small sampler pack since you may try it out first - and it has enough to see if it works for you.

First use their "soap" to clean it, please, do not use chlorinated water on your wound, use distilled water.

Second you let it air dry (and never use toilet paper on your lips - anywhere for that matter - if you want to wipe after using the toilet then get a jar with a cover, get a sponge and fill up the jar half way with hydrogen peroxide. just squeeze out the liquid and wipe - change as needed.)

Third you take the Miracle II "Gel" and smear it on.

Forth you take Aloe Vera clear gel (not the green gel, it will irritate open wounds). Put the clear aloe gel on just before the Miracle II "Gel" is dried.

leave it alone. You can do this in the morning and evening, and expect results within 3 days, maybe it will be gone within a week!

Hey everybody. It seems that of the people whoíve had biopsyís, some have had yeast infections and some havenít (I would assume that labs would always test for this, but not absolutely positive). Iím not sure what this means, but please keep us updated with how the diflucan works. Also, it was reported that for the biopsyís that didnít mention a yeast infection, only a nondescript inflammation was noted (they were described in previous threads on this board.

Hello. Can you please ask your doctors if they tested for acid fast bacilli. These types of bacteria are hard to stain/isolate (because they have a unique cell wall) and might not be found if they werenít looked for. This would be super, super helpful information. Thank you =)

the two only mycobacterial pathogens are:
1-mycobacterium tuberculosis--cause tuberculosis and is life threatening unless you are immunized ,,and i suppose that all of us vaccinated since its vaccine is given after birth.
2-mycobactirium leprae--cause leprosy life threatining ,very infectious, spread by touch ,,so if it was ,all the people you know + you are dead.

both diseases are manifested more as multisystemic symptoms and dont affect lips.

about biobsy,,
sure it will reveal yeast infection for all people , cuz candida albicans a fungi part of the normal flora of the skin((normaly present on skin)),the qusesion would be if you have a candida overgrowhth or not.
candida over growth can cuz mucocutanious candidiasis at the mucocutaniuous junction of lips((vermilion)) and is difficult to treat ((chronic)),but unless you have systemic signs and symptoms fevers,chills,etc--i dont think that you have candida.

Hi Genzowakabashi. I admit that the mycobacteria theory is a long shot, but hereís my thinking:

The two most common pathogenic mycobacteria are indeed m.tuberculosis and m.leprae. However, I was thinking that our condition might be related to one of the other 70+ environmental variants, collectively referred to as MOTTís (mycobacteria other than tuberculosis), which have been increasingly linked to opportunistic infections. (including: M. simiae, szulgai, bovis, chelonae, ulcerans, avium complex, malmoense, kansasii, xenopi, scrofulaceum, haemophilum, abscessus, marinum, fortuitum, gordonae, smegmatis, etcÖ.). I admit that cases involving these organisms are, as presently understood, relatively rare; then again, our condition is equally rare.

Normally these atypical MOTTís do not have the ability to pass through the mucosa, but itís interesting to note that almost every reported case of EC, or whatever it is we have, has been precipitated by some form of trauma to the lips (biting, accidental cutting, etc.), which could serve as a vector to an infectious agent.

Itís also interesting that one of the only people (a long time ago) on this message board who seems to have been successfully treated was prescribed clofazimine (mechanism of action is unknown, but itís believed to preferentially bind to mycobacterial DNA), a drug that is only labeled as effective for treating bacterial and mycobacterial infections (most commonly leprosy).

Itís very possible that mycobacteria are in no way related to whatís happening, but itís important to definitively rule out such a finding before writing it off.

I just noticed this: the biopsy report posted by Alesiom11 noted that the lab found polymorphonuclear (neutrophile) leucocytes. Polymorphonuclear leucocytes are ďa type of white blood cell with a nucleus that is so deeply lobated or divided that the cell looks to have multiple nuclei.Ē The usual findings associated with mycocaterial infection include dermal inflammatory infiltrates made up of lymphocytes, neutrophils, and multinucleated giant cells. It sounsds like multinucleated giant cells could easily be mistaken for polymorphonuclear leucocytes.

about the other minor micro bacteria ,,,indeed they are very rare,,,and occur mainly in immunocompromised people((i dont think we are immunocompromised coz if we are we would be suffuering many chronic microbial infections)).
more over minor micobaceria mainly case tuberculosis like disease.((less severe tuberculosis)).

polymorphonutrophils are the main cells in the acute and chronic inflamation,so its normal that they are present on lips which are chronically irritated and inflamed.

about clofazimine,, first its a third line in the treatment of leprosy and mycpbacterium avium complex,,
the drug acts in two ways:
1- interfere with production of dna in bactria
2- anti-inflamatory cortisone like action, and in our case it will decrease the peeling only when administered but as the cause of the proplem is not yet treated as soon as you stop using the drug the peeling will continue.

Hi all. Iíve only got a second (back on Sunday), but according to the biopsy report there were, in addition to other things, micro abscesses and a negative PAS. Additionally, some have reported (including myself) that we have some form of granulomas, slightly nodular swelling in our lips. According to http://pathhsw5m54.ucsf.edu/case29/image292.html from UCSF, ďcultures and special stains for acid fast organisms and fungi should be done on all tissue that shows granulomatosis and/or microabscesses.Ē

So, with a negative PAS, micro-abscesses, and granulomas activity, it would be prudent to perform an acid-fast bacilli test. It might show nothing, but it would be informative and what if it did show something.

MOTTís are rare; so is our condition.

Agreed, clofazimine is rarely prescribed and has some pretty negative side-effects. Such considerations make it all the more curious that a doc would prescribe it for our condition (I was wrong earlier: the drug also has some anti-inflammatory properties, but the mechanism is still unknown and much more effective anti-inflammatories exist; what would the motivation be for prescribing such a drug?).