Blanche, who has been employed at a museum, comes upon a new job opportunity--an assistant's position under a man named Kendall Nesbitt. She is also revealed to be a member of the Maltese Falcon Club and organizes the museum's outing (which is mentioned to be the first annual). The outing is a murder mystery weekend at the Queen of the Keys Hotel. The name of the hotel implies that it is located in the Florida Keys.
Two "guests" (who are really actors) at the hotel are first part of the murder mystery at dinner the first night there, one having been "shot" and his wife, Candy having had her throat "slit" with a Mayan sacrificial dagger. Dorothy solves the "murder" single-handedly, while Rose is just being...Rose and Sophia merely wants some birthday cake.
Soon after that, Blanche is told by Kendall that he needs to be alone with her, and she gives him her hotel room key. She gets the second key from Rose, and tells her that she can "bunk with Dorothy and Sophia tonight". Blanche then goes to the room, later, takes a shower, and puts on a negliche as she waits on Kendall. She assumes that it is Kendall, but it is a young male waiter with a bottle of champagne. The waiter discovers Kendall's "dead" body on Blanche's bed and she is suspected in his "murder," but Dorothy argues her case and that the real murderer is Posey McGlen, a rival of Blanche's for the assistant's job. Posey had been with Kendall all night, she described the bedroom with a detail that nobody saw apart from the girls and the detective, she argued with Kendall while Blanche had a shower and killed him. However it turns out that it was Part 2 of the Murder Mystery and Rose helped, to get back at Blanche for stealing her earrings, when Dorothy checked for breath with her hand mirror Rose had used Defogger on it