DOK4

(redirected from FLJ10488)

DOK4

A gene on chromosome 16q21 that encodes an enzymatically inert adaptor/scaffolding protein, which provides the docking platform for assembling multimolecular signalling complexes. DOK4 is involved in RET-mediated neurite outgrowth and neuronal differentiation; it may upregulate the MAP kinase pathway and may be involved in regulating the T-cell immune response. It is highly expressed in skeletal muscle, the heart, kidneys and liver.

All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.