"...My conclusion is that the improvement is real, and that it is due to increased basal NO from iNOS expressed during the immune system activation. I think that inducing a fever can only produce transient improvement while the NO level is acutely higher... "

Wat de Low Dose Naltrexone (LDN) betreft, interessante lectuur:

These results indicate that the antinociceptive pathway involves the O2-induced biosynthesis of NO via neuronal NOS and implicates the opiate receptors.