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Dear Healthcare provider, This communication is to remind you about the increased risk of ototoxicity following concomitant administration of gentamicin and furosemide. Nephrotoxicity and ototoxicity are the most important side effects of aminoglycosides for example Gentamicin. Furosemide is a loop diuretic which is documented to cause hearing loss in some patients especially at a high…

Pregabalin is a gama aminobutyric acid (GABA) analogue used in the treatment of pain due to nerve injury, fibromyalgia, epilepsy, and anxiety disorders. Pregabalin is registered in Uganda, and known to be prescribed in the management of neuropathic pain and anxiety disorders. Case series reviewed from the WHO global database of individual case safety reports…

Fluconazole is used in the treatment and prevention of specified fungal infections in adults and children. Management of opportunistic fungal infections among HIV infected mothers, and the inherent increased risk of fungal infections during pregnancy may call for Fluconazole use. Review of current literature has shown evidence to suggest an increased risk of spontaneous abortion…