Sometime this weekend, perhaps as soon as Friday night, Luke Gregerson will face Gary Sanchez and Aaron Judge for the first time in his career.

The Astros’ setup man offered The Post a sneak preview of what the Baby Bombers can expect from him.

“Sliders!” the right-hander said, laughing, in a telephone interview early Thursday afternoon.

Gregerson throws sliders to righty batters. It’s why he gets the big bucks, as he’s in the last season of a three-year, $18.5-million deal with Houston. For his career, he has limited righty hitters to a .194/.242/.309 slash line, although he has struggled so far this season at.281/.343/.438. He didn’t appear in the series opener, a 3-2 Astros victory.

But the 32-year-old finds himself in an unexpected position, raising big bucks for others, as a result of his experience with Team USA in the World Baseball Classic.

If you followed the tournament, you know that Team USA took on a porcelain eagle as its unofficial mascot as it rode to its first championship in the tournament’s history. Gregerson, the team’s closer, procured the eagle from his father-in-law, Chuck Kuehner, who collects them.

Now that eagle, having been autographed by team members, is up for auction through May 20. The proceeds from the sale will go to St. Jude’s Children’s Research Hospital, a choice Gregerson made to honor his father, John, who died of brain cancer this past New Year’s Day.

“This is a cause near and dear to my heart,” Gregerson said. “To support this research, you do whatever you can.”

Gregerson and the Astros improved to 24-11 — the best record in baseball – with the series-opening victory in Yankee Stadium.

The signed eagle after the World Baseball ClassicAP

“It was only a matter of time until this team started doing what it’s supposed to be doing,” he said. “We’re clicking on all cylinders.”

The team has been aided by the addition of two former Yankees, Carlos Beltran and Brian McCann, both of whom were greeted warmly Thursday night in The Bronx.

“They’re two great team players, great clubhouse guys,” Gregerson said. “They’ve definitely helped with the dynamics in the clubhouse.”

This series will present the rare instance of the Yankees being underdogs to the Astros, given the preseason projections for both. Gregerson said he and his teammates won’t be caught off guard.

“We’ve obviously been keeping up with it,” he said of the Yankees’ success. “We have baseball on TV in the clubhouse at all times. We see what’s going on in the league. With a lot of the young talent they have on their team, it reminds me of where we were in ’15 (when the Astros won a wild-card berth – and beat the Yankees in the American League wild-card game — after six consecutive losing seasons).

“It’s going to be a really good matchup. We’ll see what happens.”

You know what will happen, though, when Gregerson gets Judge or Sanchez.

–Let’s catch up on Pop Quiz questions:

1) From Anthony LoBaido of Walnut Creek, Calif.: In a 1986 episode of “The Equalizer,” a young reporter shows McCall (Robert Woodward) a cherished 1967 baseball card of a prominent player. Name the player.

2) From Gary Mintz of South Huntington: What legendary TV character, after getting insulted by his mother-in-law as soon as they were in the same room, quipped, “Starting right in, no warming up in the bullpen!”?

3) From Chris Gannon of Scotch Plains, NJ: A 1974 episode of “Kolchak: The Night Stalker” features a (fictional, at the time) World Series between two MLB teams. Name the teams.

–Your answers:

1) Pete Rose

2) Ralph Kramden (Jackie Gleason) from “The Honeymooners”

3) The Cubs and Red Sox

If you have a tidbit that connects baseball with popular culture, please send it to me at kdavidoff@nypost.com.