Posters: Natural SciencesCopyright (c) 2015 University of Iowa All rights reserved.http://ir.uiowa.edu/icru/FURF2009/NaturalSciences
Recent Events in Posters: Natural Sciencesen-usTue, 28 Apr 2015 22:12:54 PDT3600Strategies to study NADPH Oxidase 4http://ir.uiowa.edu/icru/FURF2009/NaturalSciences/20
http://ir.uiowa.edu/icru/FURF2009/NaturalSciences/20Thu, 03 Dec 2009 00:00:00 PSTSamuel CarrellEffect of Surface Functionalization on Stability of Zeolite Y Nanoparticles in Aqueous Mediumhttp://ir.uiowa.edu/icru/FURF2009/NaturalSciences/19
http://ir.uiowa.edu/icru/FURF2009/NaturalSciences/19Thu, 03 Dec 2009 00:00:00 PST
Nanocrystalline NaY zeolite is a prospective material for a variety of biomedical applications, such as drug and gene delivery, as well as magnetic resonance imaging. The stability of the zeolite framework is necessary to assure safety of the material in the human body. The NaY zeolite samples (27 and 53 nm particles) were synthesized and functionalized with chloropropyl (CP) groups and polyethyleneimine (PEI) polymer. The stability of the zeolite samples at pH 7.4 for up to 10 days was studied using ICP-OES for elemental analysis. The CP and PEI-functionalized NaY showed a higher stability at pH 7.4 than the parent zeolite samples because the zeolite framework is protected by the organic moieties.
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Suhyoung YoonMapping the Lesioned Brainhttp://ir.uiowa.edu/icru/FURF2009/NaturalSciences/18
http://ir.uiowa.edu/icru/FURF2009/NaturalSciences/18Thu, 03 Dec 2009 00:00:00 PSTAnnie E. TyeMorphometrics Research on Megalonyx Scapulae from the Tarkio Valley Ground Sloth Projecthttp://ir.uiowa.edu/icru/FURF2009/NaturalSciences/17
http://ir.uiowa.edu/icru/FURF2009/NaturalSciences/17Thu, 03 Dec 2009 00:00:00 PSTJustine C. HartExtent of Compliance with Recommended Therapy after Total Knee Replacement and Subsequent Recovery of Knee Joint Functionhttp://ir.uiowa.edu/icru/FURF2009/NaturalSciences/16
http://ir.uiowa.edu/icru/FURF2009/NaturalSciences/16Thu, 03 Dec 2009 00:00:00 PSTTyler Johnston et al.A novel technique to study the time course of morphological and functional vascular responses to hypertension in conscious ratshttp://ir.uiowa.edu/icru/FURF2009/NaturalSciences/15
http://ir.uiowa.edu/icru/FURF2009/NaturalSciences/15Thu, 03 Dec 2009 00:00:00 PST
A novel technique to study the time course of morphological and functional vascular responses to hypertension in conscious rats Harald M. Stauss, Katie M. Leick, Jason W. Burkle, Diane L. Rotella, Kevin R. Rarick, Jonathan D. Alterie, Joshua R. Nelson, Thomas A. Salter, Michael J. Harvey, Sung H. Kim, Thomas Ebnet, Michael G. Anderson* Departments of Integrative Physiology and Molecular Physiology & Biophysics*, The University of Iowa, Iowa City, IA Assessment of morphological vascular responses to exposure to cardiovascular risk factors in experimental animals requires ex vivo experiments that do not allow assessment of the time course of vascular alterations in individual subjects. We used a slit-lamp biomicroscope (resolution < 1 >μm) to photograph the long posterior ciliary artery (LPCA) of the iris in conscious normotensive Wistar Kyoto rats (WKY, n=10) and spontaneously hypertensive rats (SHR, n=10) on regular-salt diet (RS) and in SHR (n=10) on high-salt diet (HS). The same segment along the LPCA was imaged in consecutive weekly imaging sessions and an imaging software was used to determine the wall to lumen (W/L) ratio. After 4 weeks systolic blood pressure (SBP) did not change in WKY (115±5 vs. 111±5 mmHg) and SHR-RS (148±7 vs. 155±3 mmHg) but increased significantly in SHR-RS (139±5 mmHg vs. 166±6 mmHg, p< 0.05). The time course of the changes in W/L ratio of the LPCA mirrored the time course of the SBP changes. While W/L ratio did not change in WKY-RS (+12±10%) and SHR-RS (+18±17%), there was a 39±14% increase in W/L ratio in SHR-HS. Since the LPCA was not dilated pharmacologically the W/L ratio assessed in this study may reflect the combination of morphologic alterations and changes in vascular tone. In vivo imaging of the LPCA may allow assessment of the time course of morphological and functional vascular responses to hypertension in conscious rats.
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Tom A. SalterAntibody Mediated Identification of Cyclin G2 and its Role in Cell Cycle Arresthttp://ir.uiowa.edu/icru/FURF2009/NaturalSciences/14
http://ir.uiowa.edu/icru/FURF2009/NaturalSciences/14Thu, 03 Dec 2009 00:00:00 PST
Cancer cells have lost control of their divisional regulation, leading to uncontrolled growth. This may eventually lead to invasion (intrusion on and destruction of nearby tissues) and metastasis (spread to other locations in the body via the lymphatic system or bloodstream). In the cell, increased levels of the cell cycle protein Cyclin G2 have been correlated with cell cycle arrest. It has been shown that in many cancer cells, the level of G2 is significantly decreased. Thus, methods of detecting Cyclin G2 levels are important in determining its exact role in cancer development. To accomplish this, antibodies specific to Cyclin G2 were generated by animal immunization, sequentially purified, and then applied to cell samples through immunoblotting. The extent of this antibody attachment allowed for the accurate quantification and evaluation of Cyclin G2 levels in cells.
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Eric MouNeural Differentiation of Reprogrammed Human Skin Keratinocyteshttp://ir.uiowa.edu/icru/FURF2009/NaturalSciences/13
http://ir.uiowa.edu/icru/FURF2009/NaturalSciences/13Thu, 03 Dec 2009 00:00:00 PSTMohammed A. SaidExamining the Effects of VAP on Vinculinhttp://ir.uiowa.edu/icru/FURF2009/NaturalSciences/12
http://ir.uiowa.edu/icru/FURF2009/NaturalSciences/12Thu, 03 Dec 2009 00:00:00 PSTMelissa L. PalmaPurification of factors controlling the elongation phase of transcription by RNA polymerase IIhttp://ir.uiowa.edu/icru/FURF2009/NaturalSciences/11
http://ir.uiowa.edu/icru/FURF2009/NaturalSciences/11Thu, 03 Dec 2009 00:00:00 PSTNicholas Loudas