Poitier made his film debut playing part of Tec's crew in the 2003 comedy Malibu's Most Wanted, which also featured Greg Grunberg. He then had a supporting role in the crime thriller Never Die Alone, along with Tommy "Tiny" Lister, Jr. and Henry Gibson. He also had a supporting role in the 2005 war film Jarhead, with Scott MacDonald.

For television, Poitier has made both credited and uncredited appearances on such series as True Blood, Dollhouse, The Practice, CSI:NY, Charmed, Firefly, ALIAS, Judging Amy,Sheena Queen of the Jungle, Boston Legal, and Boomtown, the latter of which starred Neal McDonough. Poitier also worked with Fran Bennett, Tom Wright, and Star Trek: The Next Generation's LeVar Burton during his stint on Boomtown.