Contents

In the 7th century BC,[2] Greek influence in the region becomes prominent when Corinth settled Anactorium, Sollium and Leucas, and Kefalonia settled Astacus. Settlements in Alyzeia, Coronta, Limnaea, Medion, Oeniadae, Palaerus, Phytia and Stratus are also mentioned by Thucydides, this latter city being the seat of a loose confederation of Acarnanian powers that was maintained until the late 1st century BC.

Because it is located strategically on the maritime route to Italy, Acarnania was emmired in many wars. In 5th century BC, the Corinthians were forced out of their Acarnanian settlements by Athens. In 4th century BC, c. 390 BC, the cities of Acarnania surrendered to the Spartans under King Agesilaus, and continued to be Spartan allies until joining the Second Athenian Empire in 375 BC. The Acarnanians later sided with Boeotia in their fight against Sparta, and with Athens against Philip II of Macedon at Chaeronea.

Ancient coin of Acarnania, Circa 300-167 BC

Acarnania thereafter came under Macedonian rule. In 314 BC, at the behest of Macedonian king Cassander, the settlements of Acarnania lying near the Aetolian border were conglomerated into fewer, larger settlements. Still, border conflicts with the Aetolians were frequent, and led to Acarnania's territory being partitioned between Aetolia and Epirus, c. 250 BC. After the fall of the king of Epirus, the Acarnanian territory that had been given to Epirus regained its independence, and gained Leucas from Epirus, which became the capital of the region.