Product Details anti-XIAP Antibody

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results. 2. Please refer to us for technical protocols. 3. Source of all serum proteins is from USDA inspected abattoirs located in the United States. 4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

Purification

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen

Human hILP aa. 268-426

Clone

48-hILP-XIAP

Isotype

IgG1

Target Details XIAP

Apoptosis is a genetically programmed, selective process of cell death that occurs during normal cell differentiation and development of multicellular organisms. Viruses depend on the biosynthetic machinery of their host cell for the production of progeny and survival. Therefore, many viruses encode proteins that protect the cell from apoptosis. hILP (human IAP-like protein) is a human homologue of the viral IAP (Inhibitor of Apoptosis Protein). hILP is a widely expressed cytoplasmic protein of 497 amino acids with three BIR (Baculovirus IAP repeats) domains and a C-terminal RING finger domain. hILP-transfected cells are protected against the apoptotic effects of Sindbis virus infection and ICE (interleukin-1beta converting enzyme) expression. This product is sold under license from Aegera Therapeutics, Inc. This antibody is routinely tested by western blot analysis.Synonyms: hILP