Background: The immunosuppresion in HIV patients makes them highly susceptible to microbial infections. The
aim of the study was to establish whether HIV stage (as depicted by CD4+ T lymphocyte counts) could
independently ...

The influence of prophylactic metronidazole on vaginal
carriage rates of anaerobes and the development of postoperative
anaerobic infection was studied in 104 women
who underwent abdominal hysterectomy. Metronidazole
...

Introduction: The study of the aetiology of periodontal diseases has continued for decades with much
progress shown in the last two decades. Having moved through periods of “whole” plaque
(with emphasis on mass) being ...

Candida species are a common cause of infection in immune-compromised HIV-positive individuals, who are usually treated with the antifungal drug, fluconazole in public hospitals in Africa. However, information about the ...

Severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) caused a severe outbreak in several regions of the world in 2003. The
SARS-CoV genome is predicted to contain 14 functional open reading frames (ORFs). The ...

Severe acute respiratory syndrome (SARS), a life-threatening disease, is caused by the newly identified virus SARS coronavirus (SARSCoV).
In order to study the spike (S) protein of this highly contagious virus, we established ...

The severe acute respiratory syndrome coronavirus (SARS-CoV) genome contains open reading frames
(ORFs) that encode for several genes that are homologous to proteins found in all known coronaviruses. These
are the replicase ...

Preterm birth significantly impacts on neonatal
morbidity and mortality and is apparently increasing worldwide.
Several studies have attempted to define a causative role
for periodontal disease in adverse pregnancy ...

Besides genes that are homologous to proteins found in other coronaviruses, the severe acute respiratory
syndrome coronavirus genome also contains nine other potential open reading frames. Previously, we have
characterized ...

The genome of the severe acute respiratory syndrome coronavirus encodes for eight accessory viral proteins with no known homologues in other
coronaviruses. One of these is the 3b protein, which is encoded by the second ...

INTRODUCTION: The African continent has the highest burden of HIV infection, accounting for approximately 65% of new infections globally. Oral candidiasis is a major cause of increased morbidity in HIV-infected individuals ...

More than 20 million infants in the world (15.5% of all births) are born with low birth weight. Ninety-five
percent of them are in developing countries. The objective of this study was to examine different factors
which ...

A respiratory disease caused by a novel coronavirus, termed the severe acute respiratory syndrome coronavirus (SARS-CoV), was first reported in China in late 2002. The subsequent efficient human-to-human transmission of ...

Severe acute respiratory syndrome coronavirus (SARS-CoV) 7a is an accessory protein with no known homologues. In this study, we
report the interaction of a SARS-CoV 7a and small glutamine-rich tetratricopeptide repeat-containing ...

The treatment of invasive candidiasis and other Candida infections with the appropriate antifungal agent is assisted by the identification of Candida isolates to the species level. Rapid and accurate methods of differentiation ...

Even though coronavirus infection of humans is not normally associated with severe diseases, the identification
of the coronavirus responsible for the outbreak of severe acute respiratory syndrome showed that highly ...

RNA helicases of the DEAD (Asp-Glu-Ala-Asp)-box family of
proteins are involved in many aspects of RNA metabolism from
transcription to RNA decay, but most of them have also been
shown to be multifunctional. The DEAD-box ...