My research interests involve to investigate the molecular and cellular metabolic pathways in innate T cells and how they are different from conventional T cells. In our laboratory, we have PLZF tg mice in which CD4 T cells behaves like NKT cells, therefore, I am going to demonstrate the similarities in PLZF tg CD4 and innate NKT cells. Till now, we have demonstrated that PLZF tg CD4 T cells produce more ROS similar to NKT cells and produce more cytokines without activation. I have also demonstrated that PLZF tg CD4 T cells as compared to conventional CD4 from WTB6 mice, have less glucose...

My research interests have been to identify the key elements for chemotherapeutic resistance in ovarian cancer microenvironment at both molecular and cellular levels. I explore the impact of fibroblasts and immune cells on cisplatin resistance and sensitivity in ovarian cancer cells and identify that effector T cells abrogate fibroblasts-mediated cisplatin resistance. This finding provides a scientific rationale for the combination of chemotherapy and immunotherapy.