Dupuytren Literature: Abnormalities in Normal Appearing Tissue

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Others have not. When considering latent disease, note that Dupuytren affects superficial palmar fascia but never the transverse palmar fascia. One possible explanation is that these two fascial layers are subjected to very different mechanical environments. Another is that the superficial palmar fascia is in direct continuity with biologically active subcutaneous fat (PDF) but the transverse palmar fascia is not. Studies above compared diseased vs. normal appearing superficial palmar fascia from the same patient. Some studies below used transverse palmar fascia as controls which are not biologically comparable to normal appearing superficial palmar fascia controls.