The remark appeared to catch many in the predominately white crowd by surprise, particularly a woman standing on stage behind Trump

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Republican Presidential nominee Donald Trump speaks to a crowd at the Mississippi Coliseum on August 24, 2016 in Jackson, Mississippi. Thousands attended to listen to Trump's address in the traditionally conservative state of Mississippi.

Republican presidential nominee Donald Trump, who has been aggressively courting African-American voters in recent weeks, accused Hillary Clinton of being a "bigot" who panders to minorities.

"Hillary Clinton is a bigot who sees people of color only as votes, not as human beings worthy of a better future," Trump said Wednesday during a campaign rally in Jackson, Mississippi.

The remark appeared to catch many in the predominately white crowd by surprise, particularly a woman standing on stage behind Trump. Video of the woman grimacing at the comment as her eyes widened in shock was shared on social media. Her reaction seemed to encapsulate the audience's uncertain response: a delayed round of staggered cheers and applause.

"He is taking a hate movement mainstream," the former secretary of state said, arguing Trump is "very much peddling bigotry and prejudice and paranoia."

Clinton is set to address Trump's recent attacks in a speech in Nevada on Thursday afternoon.

Trump Booed Leaving New York Times

President Elect Donald Trump is booed as he walks through the lobby of The New York Times Building after a 75-minute meeting with Times journalists. The lobby of the Times building is open to the public, and a large crowd had gathered by the time he departed. (Published Tuesday, Nov. 22, 2016)

Critics have repeatedly accused Trump of pushing racist and bigoted views during his campaign, including calling for the U.S. to build a wall across its Mexican border to stem illegal immigration and to fight terrorism by temporarily banning Muslims from entering the U.S.

Trump also gave a vague preview of his new immigration policy, which is slated to be unveiled next week. Without offering any specifics, he said any immigration policy he supports must pass three tests: It should improve the wages, safety and quality of life for U.S. citizens.