Uses for Tripohist D

Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant, and an analgesic, in addition to a medicine for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Also, in general, it is best to buy a product that includes only those medicines you really need. If you have questions about which product to buy, check with your pharmacist.

Since different products contain ingredients that will have different precautions and side effects, it is important that you know the ingredients of the medicine you are taking. The different kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines—Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are:

Bromodiphenhydramine

Brompheniramine

Carbinoxamine

Chlorpheniramine

Dexchlorpheniramine

Diphenhydramine

Doxylamine

Phenindamine

Pheniramine

Phenyltoloxamine

Pyrilamine

Promethazine

Triprolidine

Decongestants—Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in patients who have high blood pressure. These include:

Ephedrine

Phenylephrine

Pseudoephedrine

Antitussives—Antitussives help relieve coughing and are some contain a narcotic. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if used for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Narcotic antitussives

Codeine

Dihydrocodeine

Hydrocodone

Hydromorphone

Non-narcotic antitussives

Carbetapentane

Caramiphen

Dextromethorphan

Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and cold medicines is guaifenesin. Other ingredients added as expectorants (for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide, and sodium citrate) have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics—Analgesics are used in these combination medicines to help relieve the aches and pain that may occur with the common cold. These include:

Acetaminophen

Aspirin

Other salicylates such as salicylamide and sodium salicylate

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medicines are taken together for a long time. However, taking the recommended amounts of combination medicines that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics—Anticholinergics, such as homatropine may help produce a drying effect in the nose and chest.

These cough and cold combinations are available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

Before using Tripohist D

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Very young children are usually more sensitive to the effects of this medicine. Before giving any of these combination medicines to a child, check the package label very carefully. Some of these medicines are too strong for use in children. If you are not certain whether a specific product can be given to a child, or if you have any questions about the amount to give, check with your health care professional, especially if it contains:

Antihistamines—Nightmares, unusual excitement, nervousness, restlessness, or irritability may be more likely to occur in children taking antihistamines.

Decongestants (e.g., ephedrine, phenylephrine, pseudoephedrine—Increases in blood pressure may be more likely to occur in children taking decongestants.

Iodides (e.g., calcium iodide and iodinated glycerol)—These medicines pass into the breast milk and may cause unwanted effects, such as underactive thyroid, in the baby.

Narcotic antitussives (e.g., codeine, dihydrocodeine, hydrocodone, and hydromorphone)—Breathing problems may be especially likely to occur in children younger than 2 years of age taking narcotic antitussives. Also, unusual excitement or restlessness may be more likely to occur in children receiving these medicines.

Salicylates (e.g., aspirin)—Do not give medicines containing aspirin or other salicylates to a child or teenager with a fever or other symptoms of a virus infection, especially flu or chickenpox, without first discussing its use with your child's doctor. This is very important because salicylates may cause a serious illness called Reye's syndrome in children with fever caused by a virus infection, especially flu or chickenpox. Also, children may be more sensitive to the aspirin or other salicylates contained in some of these medicines, especially if they have a fever or have lost large amounts of body fluid because of vomiting, diarrhea, or sweating.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

Geriatric

The elderly are usually more sensitive to the effects of this medicine, especially if it contains:

Antihistamines—Confusion, difficult or painful urination, dizziness, drowsiness, feeling faint, or dryness of mouth, nose, or throat may be more likely to occur in elderly patients. Also, nightmares or unusual excitement, nervousness, restlessness, or irritability may be more likely to occur in the elderly taking antihistamines.

Decongestants (e.g., ephedrine, phenylephrine, pseudoephedrine—Confusion, hallucinations, drowsiness, or convulsions (seizures) may be more likely to occur in the elderly, who are usually more sensitive to the effects of this medicine. Also, increases in blood pressure may be more likely to occur in elderly persons taking decongestants.

Pregnancy

The occasional use of a cough/cold combination is not likely to cause problems in the fetus or in the newborn baby. However, when these medicines are used at higher doses and/or for a long time, the chance that problems might occur may increase. For the individual ingredients of these combinations, the following information should be considered before you decide to use a particular cough/cold combination:

Acetaminophen—Studies on birth defects have not been done in humans. However, acetaminophen has not been shown to cause birth defects or other problems in humans.

Alcohol—Some of these combination medicines contain a large amount of alcohol. Too much use of alcohol during pregnancy may cause birth defects.

Antihistamines—Antihistamines have not been shown to cause problems in humans.

Caffeine—Studies in humans have not shown that caffeine causes birth defects. However, studies in animals have shown that caffeine causes birth defects when given in very large doses (amounts equal to the amount of caffeine contained in 12 to 24 cups of coffee a day).

Codeine—Although studies on birth defects with codeine have not been done in humans, it has not been reported to cause birth defects in humans. Codeine has not been shown to cause birth defects in animal studies, but it caused other unwanted effects. Also, regular use of narcotics during pregnancy may cause the baby to become dependent on the medicine. This may lead to withdrawal side effects after birth. In addition, narcotics may cause breathing problems in the newborn baby if taken by the mother just before delivery.

Hydrocodone—Although studies on birth defects with hydrocodone have not been done in humans, it has not been reported to cause birth defects in humans. However, hydrocodone has been shown to cause birth defects in animals when given in very large doses. Also, regular use of narcotics during pregnancy may cause the baby to become dependent on the medicine. This may lead to withdrawal side effects after birth. In addition, narcotics may cause breathing problems in the newborn baby if taken by the mother just before delivery.

Iodides (e.g., calcium iodide and iodinated glycerol)—Not recommended during pregnancy. Iodides have caused enlargement of the thyroid gland in the fetus and resulted in breathing problems in newborn babies whose mothers took iodides in large doses for a long period of time.

Phenylephrine—Studies on birth defects with phenylephrine have not been done in either humans or animals.

Pseudoephedrine—Studies on birth defects with pseudoephedrine have not been done in humans. In animal studies pseudoephedrine did not cause birth defects but did cause a decrease in average weight, length, and rate of bone formation in the animal fetus when given in high doses.

Salicylates (e.g., aspirin)—Studies on birth defects in humans have been done with aspirin, but not with salicylamide or sodium salicylate. Salicylates have not been shown to cause birth defects in humans. However, salicylates have been shown to cause birth defects in animals.

Some reports have suggested that too much use of aspirin late in pregnancy may cause a decrease in the newborn's weight and possible death of the fetus or newborn infant. However, the mothers in these reports had been taking much larger amounts of aspirin than are usually recommended. Studies of mothers taking aspirin in the doses that are usually recommended did not show these unwanted effects. However, there is a chance that regular use of salicylates late in pregnancy may cause unwanted effects on the heart or blood flow in the fetus or newborn baby.

Use of salicylates, especially aspirin, during the last 2 weeks of pregnancy may cause bleeding problems in the fetus before or during delivery, or in the newborn baby. Also, too much use of salicylates during the last 3 months of pregnancy may increase the length of pregnancy, prolong labor, cause other problems during delivery, or cause severe bleeding in the mother before, during, or after delivery. Do not take aspirin during the last 3 months of pregnancy unless it has been ordered by your doctor.

Breastfeeding

If you are breastfeeding, the chance that problems might occur depends on the ingredients of the combination. For the individual ingredients of these combinations, the following apply:

Acetaminophen—Acetaminophen passes into the breast milk. However, it has not been reported to cause problems in nursing babies.

Alcohol—Alcohol passes into the breast milk. However, the amount of alcohol in recommended doses of this medicine does not usually cause problems in nursing babies.

Antihistamines—Small amounts of antihistamines pass into the breast milk. Antihistamine-containing medicine is not recommended for use while breastfeeding since most antihistamines are especially likely to cause side effects, such as unusual excitement or irritability, in the baby. Also, since antihistamines tend to decrease the secretions of the body, the flow of breast milk may be reduced in some patients.

Caffeine—Small amounts of caffeine pass into the breast milk and may build up in the nursing baby. However, the amount of caffeine in recommended doses of this medicine does not usually cause problems in nursing babies.

Codeine and other narcotic cough medicines (e.g., dihydrocodeine, hydrocodone, and hydromorphone)—Codeine is changed to morphine in the body. Some people change codeine to morphine more quickly than others. These individuals are called "ultra-rapid metabolizers of codeine". If a nursing mother is an ultra-rapid metabolizer of codeine, it could lead to a morphine overdose in the nursing baby and cause very serious side effects. A nursing mother should talk to her doctor if she has any questions about taking codeine or about how this medicine may affect her baby .

Decongestants (e.g., ephedrine, phenylephrine, pseudoephedrine—Phenylephrine has not been reported to cause problems in nursing babies. Ephedrine and pseudoephedrine pass into the breast milk and may cause unwanted effects in nursing babies (especially newborn and premature babies).

Iodides (e.g., calcium iodide and iodinated glycerol)—These medicines pass into the breast milk and may cause unwanted effects, such as underactive thyroid, in the baby.

Salicylates (e.g., aspirin)—Salicylates pass into the breast milk. Although salicylates have not been reported to cause problems in nursing babies, it is possible that problems may occur if large amounts are taken regularly.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these medicines, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.

Alfuzosin

Amiodarone

Amisulpride

Amitriptyline

Amprenavir

Anagrelide

Apomorphine

Aripiprazole

Aripiprazole Lauroxil

Arsenic Trioxide

Artemether

Asenapine

Astemizole

Atazanavir

Azithromycin

Bedaquiline

Bepridil

Boceprevir

Buprenorphine

Buserelin

Ceritinib

Chloroquine

Chlorpromazine

Ciprofloxacin

Cisapride

Citalopram

Clarithromycin

Clofazimine

Clomipramine

Clorgyline

Clozapine

Cobicistat

Crizotinib

Cyclobenzaprine

Cyclopropane

Dabrafenib

Darunavir

Dasabuvir

Dasatinib

Defibrotide

Degarelix

Delamanid

Delavirdine

Desipramine

Deslorelin

Deutetrabenazine

Dichlorphenamide

Dihydroergotamine

Disopyramide

Dofetilide

Dolasetron

Domperidone

Donepezil

Doravirine

Doxepin

Dronedarone

Droperidol

Ebastine

Efavirenz

Elvitegravir

Encorafenib

Entrectinib

Eribulin

Erythromycin

Escitalopram

Famotidine

Felbamate

Fingolimod

Flecainide

Fluconazole

Fluoxetine

Fluvoxamine

Formoterol

Foscarnet

Fosphenytoin

Furazolidone

Galantamine

Gatifloxacin

Gemifloxacin

Glasdegib

Gonadorelin

Goserelin

Granisetron

Halofantrine

Haloperidol

Halothane

Histrelin

Hydroquinidine

Hydroxychloroquine

Hydroxyzine

Ibutilide

Iloperidone

Imipramine

Indinavir

Influenza Virus Vaccine, Live

Inotuzumab Ozogamicin

Iproniazid

Isocarboxazid

Itraconazole

Ivabradine

Ivosidenib

Ketoconazole

Ketorolac

Lapatinib

Lenvatinib

Leuprolide

Levofloxacin

Levomethadyl

Linezolid

Lofexidine

Lumefantrine

Macimorelin

Maraviroc

Mefloquine

Mesoridazine

Methadone

Methotrimeprazine

Methylene Blue

Metronidazole

Mifepristone

Mizolastine

Moclobemide

Moricizine

Moxifloxacin

Nafarelin

Nalmefene

Naltrexone

Nefazodone

Nelfinavir

Nialamide

Nilotinib

Norfloxacin

Octreotide

Ofloxacin

Olanzapine

Ombitasvir

Ondansetron

Osimertinib

Paliperidone

Panobinostat

Papaverine

Pargyline

Paritaprevir

Paroxetine

Pasireotide

Pazopanib

Pentamidine

Perphenazine

Phenelzine

Pimavanserin

Pimozide

Pipamperone

Piperaquine

Pitolisant

Posaconazole

Potassium

Praziquantel

Probucol

Procainamide

Procarbazine

Prochlorperazine

Promethazine

Propafenone

Protriptyline

Quetiapine

Quinidine

Quinine

Ranolazine

Rasagiline

Ribociclib

Rilpivirine

Riociguat

Risperidone

Ritonavir

Safinamide

Saquinavir

Selegiline

Sertindole

Sertraline

Sevoflurane

Sibutramine

Sodium Oxybate

Sodium Phosphate

Sodium Phosphate, Dibasic

Sodium Phosphate, Monobasic

Solifenacin

Sorafenib

Sotalol

Sparfloxacin

Sulpiride

Sultopride

Sunitinib

Tacrolimus

Tamoxifen

Telaprevir

Telavancin

Telithromycin

Tenofovir Alafenamide

Tetrabenazine

Thioridazine

Tipranavir

Tizanidine

Toloxatone

Tolterodine

Toremifene

Tranylcypromine

Trazodone

Triclabendazole

Trimipramine

Triptorelin

Vandetanib

Vardenafil

Vemurafenib

Venlafaxine

Vilanterol

Vinflunine

Voriconazole

Vorinostat

Ziprasidone

Zolmitriptan

Zotepine

Zuclopenthixol

Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Abciximab

Acarbose

Aceclofenac

Acemetacin

Acenocoumarol

Acepromazine

Acetyldigoxin

Adenosine

Alefacept

Alfentanil

Alipogene Tiparvovec

Almotriptan

Alprazolam

Alteplase, Recombinant

Amifampridine

Amiloride

Amineptine

Amiodarone

Amisulpride

Amitriptyline

Amitriptylinoxide

Amobarbital

Amoxapine

Amphetamine

Amprenavir

Amtolmetin Guacil

Amygdalin

Anagrelide

Ancrod

Anileridine

Anisindione

Antithrombin III Human

Apixaban

Aprepitant

Aprobarbital

Ardeparin

Argatroban

Aripiprazole

Armodafinil

Arsenic Trioxide

Asenapine

Aspirin

Atazanavir

Axitinib

Baclofen

Balsalazide

Bemiparin

Bendroflumethiazide

Benperidol

Benzhydrocodone

Benzphetamine

Benzthiazide

Betamethasone

Betrixaban

Bisacodyl

Bismuth Subsalicylate

Bivalirudin

Boceprevir

Bosentan

Brigatinib

Bromazepam

Bromfenac

Bromocriptine

Bromopride

Bromperidol

Brompheniramine

Bucindolol

Budesonide

Bufexamac

Bumetanide

Buprenorphine

Bupropion

Buspirone

Butabarbital

Butalbital

Butorphanol

Calcifediol

Cangrelor

Cannabidiol

Caplacizumab-yhdp

Carbamazepine

Carbinoxamine

Carisoprodol

Carmustine

Carphenazine

Carteolol

Carvedilol

Celecoxib

Ceritinib

Certoparin

Cetirizine

Chloral Hydrate

Chlordiazepoxide

Chlorothiazide

Chlorpheniramine

Chlorpromazine

Chlorpropamide

Chlorthalidone

Chlorzoxazone

Choline Magnesium Trisalicylate

Choline Salicylate

Cilostazol

Cimetidine

Cinacalcet

Ciprofloxacin

Citalopram

Clarithromycin

Clobazam

Clomipramine

Clonazepam

Clonixin

Clopamide

Clopidogrel

Clorazepate

Clorgyline

Clozapine

Cobicistat

Cobimetinib

Cocaine

Codeine

Conivaptan

Cortisone

Crizotinib

Cyclobenzaprine

Cyclopenthiazide

Cyclosporine

Dabigatran Etexilate

Daclatasvir

Dalteparin

Danaparoid

Dantrolene

Darunavir

Dasabuvir

Deferasirox

Deferoxamine

Defibrotide

Deflazacort

Delavirdine

Dermatan Sulfate

Desipramine

Desirudin

Deslanoside

Desmopressin

Desogestrel

Desvenlafaxine

Dexamethasone

Dexibuprofen

Dexketoprofen

Dexmedetomidine

Dextroamphetamine

Dextromethorphan

Dezocine

Diacetylmorphine

Diazepam

Diazoxide

Dibenzepin

Dichloralphenazone

Diclofenac

Dicumarol

Dienogest

Difenoxin

Diflunisal

Digitalis

Digitoxin

Digoxin

Dihydroartemisinin

Dihydrocodeine

Dilevalol

Diltiazem

Diphenhydramine

Diphenoxylate

Dipyridamole

Dipyrone

Dixyrazine

Dolasetron

Dolutegravir

Domperidone

Donepezil

Dothiepin

Doxepin

Doxorubicin

Doxorubicin Hydrochloride Liposome

Doxylamine

Dronedarone

Droperidol

Drospirenone

Droxicam

Duloxetine

Edoxaban

Efavirenz

Elbasvir

Eletriptan

Encorafenib

Enflurane

Enoxacin

Enoxaparin

Entacapone

Entrectinib

Enzalutamide

Epinephrine

Eplerenone

Epoprostenol

Eptifibatide

Erdafitinib

Ergonovine

Erlotinib

Erythromycin

Escitalopram

Esketamine

Eslicarbazepine Acetate

Estazolam

Estradiol

Estradiol Cypionate

Estradiol Valerate

Eszopiclone

Ethacrynic Acid

Ethchlorvynol

Ethinyl Estradiol

Ethopropazine

Ethylmorphine

Ethynodiol

Ethynodiol Diacetate

Etintidine

Etodolac

Etofenamate

Etonogestrel

Etoricoxib

Etravirine

Fedratinib

Felbinac

Fenoprofen

Fentanyl

Fepradinol

Feprazone

Feverfew

Fexofenadine

Flibanserin

Floctafenine

Fluconazole

Flufenamic Acid

Flunitrazepam

Fluocortolone

Fluoxetine

Fluphenazine

Flurazepam

Flurbiprofen

Fluspirilene

Fluvoxamine

Fondaparinux

Fosamprenavir

Fosaprepitant

Fosnetupitant

Fosphenytoin

Fospropofol

Frovatriptan

Furazolidone

Furosemide

Gabapentin

Gabapentin Enacarbil

Gestodene

Ginkgo

Givosiran

Glimepiride

Glipizide

Glyburide

Glycopyrrolate

Glycopyrronium Tosylate

Gossypol

Granisetron

Grazoprevir

Guanethidine

Halazepam

Haloperidol

Halothane

Hemin

Heparin

Hexobarbital

Hyaluronidase

Hydrochlorothiazide

Hydrocodone

Hydrocortisone

Hydroflumethiazide

Hydromorphone

Hydroxytryptophan

Hydroxyzine

Ibrutinib

Ibuprofen

Idelalisib

Idrocilamide

Ifosfamide

Iloprost

Imatinib

Imipenem

Imipramine

Indapamide

Indinavir

Indomethacin

Inotersen

Iobenguane I 123

Iobenguane I 131

Iproniazid

Isocarboxazid

Isoflurane

Isoniazid

Itraconazole

Ivacaftor

Ketamine

Ketazolam

Ketobemidone

Ketoconazole

Ketoprofen

Lamotrigine

Lasmiditan

Ledipasvir

Lefamulin

Lepirudin

Levalbuterol

Levobunolol

Levofloxacin

Levomilnacipran

Levonorgestrel

Levorphanol

Licorice

Linezolid

Lisdexamfetamine

Lithium

Lofepramine

Lofexidine

Lomitapide

Lopinavir

Lorazepam

Lorcaserin

Lorlatinib

Lormetazepam

Lornoxicam

Loxapine

Loxoprofen

Lumacaftor

Lumiracoxib

Macimorelin

Magnesium Salicylate

Meadowsweet

Meclizine

Meclofenamate

Medazepam

Medroxyprogesterone Acetate

Mefenamic Acid

Melitracen

Meloxicam

Melperone

Memantine

Meperidine

Mephenesin

Mephobarbital

Meprobamate

Meptazinol

Mesalamine

Mesoridazine

Mestranol

Metaxalone

Metformin

Methacholine

Methadone

Methamphetamine

Methdilazine

Methocarbamol

Methohexital

Methotrexate

Methotrimeprazine

Methoxyflurane

Methyclothiazide

Methyldopa

Methylene Blue

Methylergonovine

Methylprednisolone

Metildigoxin

Metipranolol

Metoclopramide

Metolazone

Metopimazine

Mexiletine

Mibefradil

Midazolam

Midodrine

Mifepristone

Milnacipran

Mirabegron

Mirtazapine

Mitotane

Moclobemide

Modafinil

Molindone

Moricizine

Morniflumate

Morphine

Morphine Sulfate Liposome

Nabumetone

Nadolol

Nadroparin

Nafcillin

Nalbuphine

Naproxen

Naratriptan

Nateglinide

Nefazodone

Nelfinavir

Nepafenac

Neratinib

Netupitant

Nevirapine

Nialamide

Nicomorphine

Nicorandil

Nifedipine

Niflumic Acid

Nilotinib

Nimesulide

Nimesulide Beta Cyclodextrin

Nimodipine

Nitrazepam

Nitrous Oxide

Norelgestromin

Norethindrone

Norgestimate

Norgestrel

Nortriptyline

Olanzapine

Olaparib

Olsalazine

Ombitasvir

Ondansetron

Opipramol

Opium

Opium Alkaloids

Orlistat

Orphenadrine

Oxaprozin

Oxazepam

Oxcarbazepine

Oxprenolol

Oxycodone

Oxymorphone

Oxyphenbutazone

Oxytocin

Paclitaxel

Palbociclib

Palonosetron

Panobinostat

Papaveretum

Paramethasone

Parecoxib

Paregoric

Pargyline

Paritaprevir

Parnaparin

Paroxetine

Pefloxacin

Peginterferon Alfa-2a

Peginterferon Alfa-2b

Pemetrexed

Penbutolol

Pentazocine

Pentobarbital

Pentosan Polysulfate Sodium

Pentoxifylline

Perampanel

Perazine

Periciazine

Perphenazine

Phenelzine

Phenindione

Phenobarbital

Phenprocoumon

Phenylbutazone

Phenyl Salicylate

Phenytoin

Piketoprofen

Pimozide

Pindolol

Pipamperone

Piperacetazine

Piperaquine

Pipotiazine

Piracetam

Piritramide

Piroxicam

Pitolisant

Pixantrone

Pneumococcal 13-Valent Vaccine, Diphtheria Conjugate

Polythiazide

Posaconazole

Practolol

Pralatrexate

Pranoprofen

Prasugrel

Prazepam

Prednisolone

Prednisone

Pregabalin

Pretomanid

Primidone

Procarbazine

Prochlorperazine

Proglumetacin

Promazine

Promethazine

Propiomazine

Propofol

Propranolol

Propyphenazone

Proquazone

Protein C

Protriptyline

Quazepam

Quetiapine

Quinidine

Quinine

Ramelteon

Ranitidine

Ranolazine

Rasagiline

Reboxetine

Regadenoson

Remifentanil

Remoxipride

Repaglinide

Reteplase, Recombinant

Revefenacin

Reviparin

Rifabutin

Rifampin

Rifapentine

Ritonavir

Rivaroxaban

Rizatriptan

Rofecoxib

Rolapitant

Salicylamide

Salicylic Acid

Salsalate

Saquinavir

Scopolamine

Secobarbital

Secretin Human

Selegiline

Senna

Sertindole

Sertraline

Sibutramine

Simeprevir

Siponimod

Sirolimus

Sodium Oxybate

Sodium Picosulfate

Sodium Salicylate

Sonidegib

Sotalol

Spironolactone

St John's Wort

Sufentanil

Sulfasalazine

Sulindac

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Sumatriptan

Sunitinib

Suvorexant

Tacrolimus

Tapentadol

Telaprevir

Telithromycin

Temazepam

Teniposide

Tenofovir Disoproxil Fumarate

Tenoxicam

Terbinafine

Terfenadine

Tertatolol

Thiabendazole

Thiethylperazine

Thiopental

Thiopropazate

Thioproperazine

Thioridazine

Tianeptine

Tiaprofenic Acid

Ticagrelor

Ticlopidine

Tilidine

Timolol

Tinzaparin

Tiotropium

Tirofiban

Tizanidine

Tolazamide

Tolbutamide

Tolfenamic Acid

Tolmetin

Tolonium Chloride

Tolvaptan

Topiramate

Torsemide

Tramadol

Tranylcypromine

Trazodone

Treprostinil

Triamterene

Triazolam

Trichlormethiazide

Trifluoperazine

Trifluperidol

Triflupromazine

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Troleandomycin

Tryptophan

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Varicella Virus Vaccine, Live

Velpatasvir

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Verapamil

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Voriconazole

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Zolpidem

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Zotepine

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Using medicines in this class with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use your medicine, or give you special instructions about the use of food, alcohol, or tobacco.

Ethanol

Grapefruit Juice

Tobacco

Other medical problems

The presence of other medical problems may affect the use of medicines in this class. Make sure you tell your doctor if you have any other medical problems, especially:

Alcohol abuse (or history of)—Acetaminophen-containing medicines increase the chance of liver damage; also, some of the liquid medicines contain a large amount of alcohol.

Anemia or

Gout or

Hemophilia or other bleeding problems or

Stomach ulcer or other stomach problems—These conditions may become worse if you are taking a combination medicine containing aspirin or another salicylate.

Brain disease or injury or

Colitis or

Convulsions (seizures) (history of) or

Diarrhea or

Gallbladder disease or gallstones—These conditions may become worse if you are taking a combination medicine containing codeine, dihydrocodeine, hydrocodone, or hydromorphone

Cystic fibrosis (in children)—Side effects of iodinated glycerol may be more likely in children with cystic fibrosis.

Emphysema, asthma, or chronic lung disease (especially in children)—Salicylate-containing medicine may cause an allergic reaction in which breathing becomes difficult.

Enlarged prostate or

Urinary tract blockage or difficult urination—Some of the effects of anticholinergics (e.g., homatropine) or antihistamines may make urinary problems worse.

Glaucoma—A slight increase in inner eye pressure may occur with the use of anticholinergics (e.g., homatropine) or antihistamines, which may make the condition worse.

Heart or blood vessel disease or

High blood pressure—Decongestant-containing medicine may increase the blood pressure and speed up the heart rate; also, caffeine-containing medicine, if taken in large amounts, may speed up the heart rate.

Kidney disease—This condition may increase the chance of side effects of this medicine because the medicine may build up in the body.

Liver disease—Liver disease increases the chance of side effects because the medicine may build up in the body; also, if liver disease is severe, there is a greater chance that aspirin-containing medicine may cause bleeding.

Thyroid disease—If an overactive thyroid has caused a fast heart rate, the decongestant in this medicine may cause the heart rate to speed up further; also, if the medicine contains narcotic antitussives (e.g., codeine), iodides (e.g., iodinated glycerol), or salicylates, the thyroid problem may become worse.

Proper use of Tripohist D

This section provides information on the proper use of a number of products that contain cough and cold combinations. It may not be specific to Tripohist D. Please read with care.

To help loosen mucus or phlegm in the lungs, drink a glass of water after each dose of this medicine, unless otherwise directed by your doctor.

Take this medicine only as directed. Do not take more of it and do not take it more often than recommended on the label, unless otherwise directed by your doctor. To do so may increase the chance of side effects.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

For patients taking the extended-release capsule or tablet form of this medicine:

Swallow the capsule or tablet whole.

Do not crush, break, or chew before swallowing.

If the capsule is too large to swallow, you may mix the contents of the capsule with applesauce, jelly, honey, or syrup and swallow without chewing.

For patients taking the extended-release oral solution or oral suspension form of this medicine:

Do not dilute with fluids or mix with other drugs.

For patients taking a combination medicine containing an antihistamine and/or aspirin or other salicylate:

Take with food or a glass of water or milk to lessen stomach irritation, if necessary.

If a combination medicine containing aspirin has a strong vinegar-like odor, do not use it. This odor means the medicine is breaking down. If you have any questions about this, check with your pharmacist.

Missed dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Keep the liquid form of this medicine from freezing. Do not refrigerate the syrup.

Precautions while using Tripohist D

If your cough has not improved after 7 days or if you have a high fever, skin rash, continuing headache, or sore throat with the cough, check with your doctor. These signs may mean that you have other medical problems.

For patients taking a codeine-containing medicine or any other narcotic analgesics (e.g., dihydrocodeine, hydrocodone, oxycodone, and pentazocine):

Contact your doctor immediately if you experience extreme sleepiness, confusion, or shallow breathing. These symptoms may indicate that you are an "ultra-rapid metabolizer of codeine". Ultra-rapid metabolizers change codeine to morphine more quickly and completely than other people. As a result, there is too much morphine in the body and more side effects of morphine than usual

For nursing mothers taking a codeine-containing medicine or any other narcotic cough medicine (dihydrocodeine, hydrocodone, or hydromorphone):

Call your doctor if you become extremely tired and have difficulty caring for your baby.

Your baby should generally nurse every two to three hours and should not sleep more than four hours at a time.

Check with your doctor or hospital emergency room immediately if your baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, difficulty breathing, or limpness. These may be symptoms of an overdose and need immediate medical attention .

For patients taking antihistamine-containing medicine:

Before you have any skin tests for allergies, tell the doctor in charge that you are taking this medicine. The results of the test may be affected by the antihistamine in this medicine.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are taking this medicine.

This medicine may cause some people to become drowsy, dizzy, or less alert than they are normally.

Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.

When taking antihistamines on a regular basis, make sure your doctor knows if you are taking large amounts of aspirin at the same time (as in arthritis or rheumatism). Effects of too much aspirin, such as ringing in the ears, may be covered up by the antihistamine.

Antihistamines may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.

For patients taking decongestant-containing medicine:

This medicine may add to the central nervous system (CNS) stimulant effects of diet aids. Do not use medicines for diet or appetite control while taking this medicine unless you have checked with your doctor.

This medicine may cause some people to be nervous or restless or to have trouble in sleeping. If you have trouble in sleeping, take the last dose of this medicine for each day a few hours before bedtime. If you have any questions about this, check with your doctor.

Before having any kind of surgery (including dental surgery) or emergency treatment, tell the medical doctor or dentist in charge that you are taking this medicine.

This medicine will add to the effects of alcohol and other central nervous system (CNS) depressants (medicines that slow down the nervous system, possibly causing drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are taking this medicine.

This medicine may cause some people to become drowsy, dizzy, less alert than they are normally, or to feel a false sense of well-being. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert and clearheaded.

Nausea or vomiting may occur after taking a narcotic antitussive. This effect may go away if you lie down for a while. However, if nausea or vomiting continues, check with your doctor.

Dizziness, lightheadedness, or fainting may be especially likely to occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem.

Before having any kind of surgery (including dental surgery) or emergency treatment, tell the medical doctor or dentist in charge that you are taking this medicine.

Make sure your doctor knows if you are planning to have any future thyroid tests. The results of the thyroid test may be affected by the iodine in this medicine.

For patients taking analgesic-containing medicine:

Check the label of all nonprescription (over-the-counter [OTC]), and prescription medicines you now take. If any contain acetaminophen or aspirin or other salicylates, including diflunisal or bismuth subsalicylate, be especially careful. Taking them while taking a cough/cold combination medicine that already contains them may lead to overdose. If you have any questions about this, check with your health care professional.

Do not take aspirin-containing medicine for 5 days before any surgery, including dental surgery, unless otherwise directed by your medical doctor or dentist. Taking aspirin during this time may cause bleeding problems.

If you take 8 or more 325-mg doses of aspirin every day for several days in a row.

If you take 8 or more 325-mg or 4 or more 500-mg doses of sodium salicylate.

Smaller doses or occasional use of aspirin or sodium salicylate usually will not affect urine sugar tests. If you have any questions about this, check with your health care professional, especially if your diabetes is not well controlled.

For patients taking homatropine-containing medicine:

This medicine may make you sweat less, causing your body temperature to increase. Use extra care not to become overheated during exercise or hot weather while you are taking this medicine since overheating may result in heat stroke. Also, hot baths or saunas may make you feel dizzy or faint while you are taking this medicine.

Tripohist D side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Although serious side effects occur rarely when this medicine is taken as recommended, they may be more likely to occur if: too much medicine is taken, it is taken in large doses, or it is taken for a long period of time.

Get emergency help immediately if any of the following symptoms of overdose occur:

If you are a nursing mother and you notice any of the following symptoms of overdose in your baby, get emergency help immediately:

Cold, clammy skin

confusion (severe)

convulsions (seizures)

drowsiness or dizziness (severe)

nervousness or restlessness (severe)

pinpoint pupils of eyes

slow heartbeat

slow or troubled breathing

Difficulty breathing

difficulty nursing

increased sleepiness (more than usual)

limpness

For acetaminophen-containing

Diarrhea

increased sweating

loss of appetite

nausea or vomiting

stomach cramps or pain

swelling or tenderness in the upper abdomen or stomach area

For salicylate-containing

Any loss of hearing

bloody urine

confusion

convulsions (seizures)

dizziness or lightheadedness

drowsiness (severe)

excitement or nervousness (severe)

fast or deep breathing

fever

hallucinations (seeing, hearing, or feeling things that are not there)

increased sweating

nausea or vomiting (severe or continuing)

shortness of breath or troubled breathing (for salicylamide only)

stomach pain (severe or continuing)

uncontrollable flapping movements of the hands, especially in elderly patients

unusual thirst

vision problems

For decongestant-containing

Fast, pounding, or irregular heartbeat

headache (continuing and severe)

nausea or vomiting (severe)

nervousness or restlessness (severe)

shortness of breath or troubled breathing (severe or continuing)

Check with your doctor as soon as possible if any of the following side effects occur:

For all combinations

Skin rash, hives, and/or itching

For antihistamine- or anticholinergic-containing

Clumsiness or unsteadiness

convulsions (seizures

drowsiness (severe)

dryness of mouth, nose, or throat (severe)

flushing or redness of face

hallucinations (seeing, hearing, or feeling things that are not there)

restlessness (severe)

shortness of breath or troubled breathing

slow or fast heartbeat

For iodine-containing

Headache (continuing)

increased watering of mouth

loss of appetite

metallic taste

skin rash, hives, or redness

sore throat

swelling of face, lips, or eyelids

For acetaminophen-containing

Unexplained sore throat and fever

unusual tiredness or weakness

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Constipation

decreased sweating

difficult or painful urination

dizziness or lightheadedness

drowsiness

dryness of mouth, nose, or throat

false sense of well-being

increased sensitivity of skin to sun

nausea or vomiting

nightmares

stomach pain

thickening of mucus

trouble in sleeping

unusual excitement, nervousness, restlessness, or irritability

unusual tiredness or weakness

Not all of the side effects listed above have been reported for each of these medicines, but they have been reported for at least one of them. There are some similarities among these combination medicines, so many of the above side effects may occur with any of these medicines.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 4 May 2020), Cerner Multum™ (updated 2 June 2020), Wolters Kluwer™ (updated 2 May 2020) and others.