It’s a long way from “Homeland,” but Claire Danes has signed on as the new host of Art21’s TV series, “Art in the Twenty-First Century.”

Danes will helm the show as it profiles 16 artists and the cities in which they live, including LA’s Edgar Arceneaux and Tala Madani, Chicago’s Nick Cave and Barbara Kasten, and Mexico City’s Natalia Almada and Minerva Cuevas.

Danes said: “Artists today influence how we see the world, how we express ourselves and how art can transform society.”