Metabolic Syndrome & CBD Oil: Addressing Multiple Conditions

Metabolic syndrome includes a number of conditions that have the potential to escalate into life-threatening diseases.

Metabolic syndrome covers a range of health conditions that all pose cardiovascular complications. Metabolic syndrome is shockingly common, and the American Heart Association estimates that 34% of American adults have it. Fortunately, CBD oil presents significant potential for use in managing the symptoms associated with this condition.

The risk factors associated with metabolic syndrome are obesity, high blood pressure, low HDL cholesterol/high LDL cholesterol, insulin resistance, and elevated triglycerides. Experiencing three or more of these conditions is the criteria for a clinical diagnosis. Metabolic syndrome greatly increases the risk of heart disease, stroke, and Type 2 diabetes.

Here’s a look at the benefits and effectiveness of using CBD oil as a potential treatment for metabolic syndrome.

Benefits of CBD Oil for Metabolic Syndrome

Metabolic syndrome does not have a specific cure. As mentioned above, it is a collection of conditions like high blood pressure and obesity, which can increase the risk of developing heart disease and diabetes.

The primary course of action used to treat metabolic syndrome is a lifestyle change. Diet, exercise, and stress relief can go a long way to reversing or managing the underlying conditions that are linked to metabolic syndrome. CBD oil may be able to help with some of these lifestyle changes.

The medications that are commonly prescribed to treat high blood pressure, cholesterol, and insulin resistance can carry some pretty hefty side effects. One of the primary potential benefits of CBD oil is that it may be able to produce some of the same effects of these medications without all of the associated risk.

For a better understanding of the possible benefits of CBD oil for metabolic syndrome, see the medication table below ANDspeak to your doctor. Because everyone is different, the information below should only be used as a general reference and does not replace a consultation with your physician.

Common Metabolic Syndrome Medications

Medication’s Uses

Medication’s Side Effects

Potential Benefits of CBD Oil for Metabolic Syndrome

Angiotensin II receptor blockers (ARBs) like Diovan

Used to dilate blood vessels.

Headache; diarrhea; nausea; skin rash; back and joint pain.

CBD oil can act as a vasodilator without causing the same side effects.

Effectiveness of CBD Oil for Metabolic Syndrome

There are a number of ways that CBD oil may prove to be effective in treating metabolic syndrome. While more research and clinical trials are needed, and are currently being conducted, here’s what we know so far.

CBD Oil for High Blood Pressure

CBD oil has been found to be effective at reducing high blood pressure. By dilating blood vessels, CBD allows more blood to flow through, lowering overall blood pressure.

One study conducted by the University of Nottingham revealed that a single dose of CBD oil significantly lowered blood pressure in the test subjects when they were both at rest and under stress.

A review of studies performed in 2017 examined the use of CBD oil on hemodynamics, or the dynamics of blood flow. While the data from clinical trials on CBD and human hemodynamics is limited, the review concluded that “CBD may be used as a treatment for various cardiovascular disorders, such as hypertension, myocardial infarction, and stroke.”

Another way that CBD oil can reduce blood pressure is by regulating and controlling stress levels.

CBD Oil for Stress Relief

The stress hormone, cortisol, is released in the body in periods of high stress. These elevated cortisol levels can lead the body to respond in ways that elevate blood pressure. In a study from 1993, CBD was shown to regulate cortisol excretion in the body of healthy human volunteers, effectively lowering their blood pressure.

In a study from 2013, researchers found that CBD could potentially reduce the defensive, stress-induced behaviors, like the fight-or-flight response, evoked by threatening stimuli through its effect on a serotonin receptor (5-HT1A). For the study, mice were treated with CBD as well as different doses of a 5-HT1A antagonist, and exposed to a wild snake. The fear responses were measured and results found that CBD’s anti-anxiety effects were real, and depended on the availability of the 5-HT1A receptor.

By targeting stress at the hormonal and neurotransmitter levels, CBD oil could show promise as a multi-pronged method for reducing stress and its contributions to metabolic syndrome.

CBD oil can also increase the level of adenosine found in the brain. This neurotransmitter, along with the A1 and A2 adenosine receptors, play a significant role in the reduction of cellular inflammation. By increasing available adenosine, CBD increases signaling by the A1 and A2 receptors. Researchers believe that this action is linked to CBD’s anti-inflammatory properties.

CBD Oil for Obesity

For one, CBD oil may function as an appetite suppressant. In a 2012 study, adult male rats were administered a range of cannabinoids and food consumption was measured following this treatment. CBD was found to reduce food consumption in the treated rats.

CBD may also help the body turn harmful white fat cells into the more favorable brown fat cells. White fat is used to store energy and it has been linked to heart disease and diabetes. Brown fat, on the other hand, converts calories from food into heat released by the body. Healthy individuals often have a higher ratio of brown to white fat cells.

In one study, CBD was found to transition white fat cells to brown, leading researchers to conclude that although more exploration was needed, CBD has the potential for actively combating obesity.

CBD Oil for Cholesterol

Unfortunately, at this time, there are not a lot of published studies on CBD and cholesterol. But, that doesn’t mean there isn’t a sign of promise.

Some of the research that does exist indicates that CBD oil can increase metabolism, which results in quicker processing of calories and fat, decreasing blood cholesterol levels.

Many of the products created from hemp contain omega 3 and 6 fatty acids and several polyunsaturated fats. These fats play a significant role in preventing bad cholesterol from building up in the arteries.

A study from 2011 looked into the effects of CBD on a cellular level. Researchers reported that CBD controls cholesterol homeostasis in microglial cells, which are found in the central nervous system and play a significant role in keeping it healthy. While the findings of this study are not conclusive, it does point to a potential focus for future investigation.

How to Use CBD Oil for Metabolic Syndrome

Before you begin taking CBD oil for metabolic syndrome, it is essential that you first speak to your health care provider. You will want to be sure that CBD oil is the best option for you and that you are using it as safely as possible.

Once you have had this conversation and are given the go-ahead, you will need to decide which types of CBD products you want to use.

When addressing the conditions associated with metabolic syndrome, it is likely that you will want to have a fairly consistent amount of CBD oil in your system. For this, the best options are likely to be CBD oil edibles, CBD oil tinctures or drops, and CBD oil capsules.

Edibles and capsules provide a relatively consistent dose of CBD oil, making them both convenient and worry-free methods for taking cannabidiol. Because these delivery formats need to pass through the digestive system before they can be absorbed into the bloodstream, they can take up to an hour to show effects. But, these effects can last 4 to 6 hours, meaning you probably won’t need to take more than one or two doses throughout the day.

CBD oil tinctures and drops do not need to pass through the digestive system since they are absorbed sublingually (under the tongue). These formats usually take effect within 30 minutes and can last 2 to 4 hours. With CBD oil drops and tinctures, it is easy to adjust the dose up or down as needed—to the literal drop—making them a good starting point for finding your ideal dosage. They also come in small, portable bottles, meaning you can take them on the go and use them should the need arise.

CBD flower and CBD oil vape products are also available. These items provide near-instant effects but these effects typically only last for an hour or so. These formats are better suited to pain, inflammation, and stress relief as needed.

You may find that it is a combination of products that work most effectively for you. For example, you may supplement regularly with a capsule and use a vape product or tincture during the day for relief of sudden stress and anxiety. Start slow, but do not be afraid to try a few different things to determine which is best for you.

Dosage of CBD Oil for Metabolic Syndrome

Unfortunately, when it comes to CBD oil, this is no “one size fits all” dosing recommendation. It is always best to start slow and begin with the lowest recommended dose listed on your packaging.

Once you know how your body will respond, you can adjust the dosage up or down as needed.

As a general starting point, we at CBD Oil Review have analyzed hundreds of products and come up with the following:

The CBD Oil Review Serving Standard is 25mg of CBD, taken twice daily

If this amount does not provide the results you were after, try increasing the dose by 25mg every 3-4 weeks until you find relief.

The Law. Before you begin shopping for CBD oil, be sure that it is legal in your state. CBD oil is legal at the federal level if it is derived from hemp and has 0.3% THC or less. But, not every state has come on board, so double check with your state’s cannabis laws to ensure you aren’t going to purchase a product illegally.

Check for THC. In states where cannabis is legally available for medical and recreational use, it will be possible to buy CBD oil with a THC content that is greater than 0.3%. If you live in a state that has strict regulation around cannabis, or would prefer to not ingest THC, be sure that you are shopping for products made using broad-spectrum CBD oil or a CBD oil isolate.

Look for a Certificate of Analysis (COA). Look for brands that post a Certificate of Analysis for every batch of CBD oil products they produce. These certificates are lab results that will tell you exactly what is present in your CBD oil. It will help you verify both THC and CBD concentrations and help you to avoid any heavy metal contamination.

Metabolic syndrome poses a significant risk to a large number of people and there is no specific treatment or cure. While diet and exercise go a long way to improving health, it is sometimes not enough. While the effects of CBD oil continue to be examined by researchers and medical professionals, it appears that it may be beneficial in helping people deal with the conditions associated with metabolic syndrome, and may help people to avoid contracting heart disease or Type 2 diabetes.