A Study of Naltrexone SR/ Bupropion SR in Overweight and Obese Subjects Who Are Nicotine-Dependent

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All subjects are to complete a 4 week titration period at which time subjects will be titrated up to a maintenance level of study drug. Subjects will then take the maintenance dose of study drug for an additional 20 weeks.

Other Names:

Contrave

Naltrexone SR 32 mg/Bupropion SR 360 mg daily

Behavioral: Ancillary therapy

During the study, subjects will receive ancillary therapy including counseling on smoking cessation, diet and exercise.