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Adenovirus

Definition

Adenoviruses are infectious agents that replicate in humans and many animals, often causing no, or only mild, symptoms. Owing to their large genome size and overall stability, members of this virus family are used as viral vectors, for example in vaccines or cancer therapy.

Here, a small core protein of human adenoviruses is shown to associate with histones, sequestering proteins on host chromatin and preventing inflammatory proteins from being released and triggering inflammation.