There are currently no cruises in our database that visit or depart from San Diego, CA

Cruises from San Diego depart year-round.

The Southern California city is approximately two hours south of Los Angeles. It is about a five-hour drive from Las Vegas, NV, and about six hours from Phoenix and Tucson, AZ. San Diego is known for its 70 miles of coastline and San Diego Bay, which is home to 16 bayside parks, landscaped promenades and public art. Visitors can go shopping in Seaport Village, visit the Maritime Museum, take a trip to SeaWorld and the San Diego Zoo, or take an Old Town Trolley Tour. Visit one or more of San Diego's historic districts: The Gaslamp Quarter is home to dining, shopping and entertainment, while Old Town San Diego has 15 museums, performing arts and beautiful gardens.