"Man, I never thought [Brexit] would happen," says Pitt, who also graces the magazine's upcoming men's fall issue, on sale Sept. 11. "Same way I can’t bring myself to think that Trump will be in charge."

"In the simplest terms, what brings us together is good, and what separates us is bad," he adds.

Photo: T The New York Times Style Magazine

Pitt, whose new film, Allied, arrives in theaters Nov. 23, also explains how he tries to understand Trump supporters.

"Coming from Oklahoma, southern Missouri, which leans more toward a Trump voice, I try to understand it," he shares. "You gotta understand that it’s also in our DNA. Most Americans don’t have time to watch CNN and Fox and Al Jazeera. They’re trying to make the rent, get the kids fed, they’re tired when they get home and they want to forget about everything. And so suddenly when this voice comes in — and it doesn’t have to be a voice of substance — saying he’s fed up with all of this, that’s the part that hooks into the DNA."

"As painful as it is to hear Donald Trump talk, and as embarrassing as it is as an American to hear him talk, I think it's good," Smith said. "We get to hear it. We get to know who people are and now we get to cleanse it out of our country."

Grindhouse star Rose McGowan had even stronger words in an open letter addressed to "Enablers and Donald" last month, in which she refers to Trump as "a murderer in the making."

"We, the public, are being sickened by an ever expanding assault on our right to live a healthy and free life," she wrote. "Donald and you ratings-driven colluders are holding us, the public, hostage and exposing us to disease."