ADME/DMPK

Access a full range of services for studying the metabolism and pharmacokinetics of your drug candidates—from their selection through to their approval by the regulatory authorities

We assess the metabolic and pharmacokinetic characteristics of chemical and biological substances, and can provide you with a range of customised services to characterize their ADME-T (Absorption, Distribution, Metabolism, Excretion, Toxicity) properties.

Early in vitro ADME

Early in vitro ADME studies are a crucial step in a molecule’s discovery phase. The accurate results from these studies can be used to identify the best drug candidates. The earlier the data is produced, the more effective the identification of the critical stages will be and the greater your chances of shortening development times.

Access a full range of services for your early in vitro ADME assessment as well as for the metabolic studies of drugs to select your best molecules.

Early in vivo ADME

Oncodesign has developed expertise in identifying the early pharmacokinetic profile (plasma and/or target organ) on rodent species to accelerate the optimization of the chosen molecule and the selection of drug candidates.

Animal pharmacokinetics and metabolism

Whatever the administration routes used with radio-labelled or non-radio-labelled compounds, Oncodesign can provide tailored solutions for your animal pharmacokinetics and metabolism studies:

Pharmacokinetics of plasma and urine (single or repeat dose using the Empis Pump method, sample-taking methods using traditional methods, such as Dry Blood Spot or the Culex® automated collection system).