Chemical Engineering in the Pharmaceutical Industry: R&D to Manufacturing

This book deals with various unique elements in the drug
development process within chemical engineering science and
pharmaceutical R&D. The book is intended to be used as a
professional reference and potentially as a text book reference in
pharmaceutical engineering and pharmaceutical sciences. Many of the
experimental methods related to pharmaceutical process development
are learned on the job. This book is intended to provide many of
those important concepts that R&D Engineers and manufacturing
Engineers should know and be familiar if they are going to be
successful in the Pharmaceutical Industry. These include basic
analytics for quantitation of reaction components– often
skipped in ChE Reaction Engineering and kinetics books. In addition
Chemical Engineering in the Pharmaceutical Industry
introduces contemporary methods of data analysis for kinetic
modeling and extends these concepts into Quality by Design
strategies for regulatory filings. For the current professionals,
in-silico process modeling tools that streamline
experimental screening approaches is also new and presented here.
Continuous flow processing, although mainstream for ChE, is unique
in this context given the range of scales and the complex economics
associated with transforming existing batch-plant capacity.

The book will be split into four distinct yet related parts.
These parts will address the fundamentals of analytical techniques
for engineers, thermodynamic modeling, and finally provides an
appendix with common engineering tools and examples of their
applications.

28 The Role of Simulation and Scheduling Tools in the
Development and Manufacturing of Active Pharmaceutical Ingredients
(Demetri Petrides, Alexandros Koulouris, Charles Siletti, Jose
O. Jimenez, and Pericles T. Lagonikos).

"Coverage is practical and up-to-date concerning industry practices
including, for example, software used in the design and modeling of
experiments for pharmaceutical development and for support of the
complexities of moving drugs from the laboratory to the
manufacturing plant." (Booknews, 1 April 2011)

"The book will be split into four distinct yet related parts.
These parts will address the fundamentals of analytical techniques
for engineers,thermodynamic modeling, and finally provides an
appendix with common engineering tools and examples of their
applications. " (Gadgets, 8 March 2011)

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