Fresh Air Weekend highlights some of the best interviews and reviews from past weeks, and new program elements specially paced for weekends. Our weekend show emphasizes interviews with writers, filmmakers, actors and musicians, and often includes excerpts from live in-studio concerts. This week:

Adrian Younge: Looking Back To Move Hip-Hop Forward: Spaghetti Westerns, Philadelphia soul, opera and the Wu-Tang Clan all come together in the music of Adrian Younge. He has produced and composed two new albums — one with William Hart, the lead singer of The Delfonics, and another with rapper Ghostface Killah.

'Frankenstein's Cat': Bioengineering The Animals Of The Future: Science journalist Emily Anthes talks about how scientists are engineering mice with tumors and working to create pigs that can grow organs for human transplant and insects that could serve as drones for the military.

Tegan And Sara Reach Out To New Audiences With 'Heartthrob': The twin sisters from Canada depart from their indie singer-songwriter roots with their latest album. The music on Heartthrob is often loaded with a carefully articulated sense of doubt that Tegan and Sara suggest needs to be shaken off through a triumph of the pop-music will.