NBIK15009U Cellular Signalling in
Health and Disease

The course covers leading-edge theoretical and experimental
knowledge of cellular strategies in communicating with the
extracellular environment and in coordinating complex signaling
pathways in health and disease. The course thus provides the
student with in-depth knowledge on the complexity of cellular
signaling and how aberrant signaling processing causes
developmental disorders and diseases, such as congenital heart
defects, neurological disorders, kidney diseases, metabolic
diseases, obesity, fibrosis, tumorigenesis and
cancer.

The course provides the student with a detailed and
comprehensive knowledge on how signaling systems control specified
cellular and physiological processes during development and in
tissue homeostasis (see also "Criteria for exam
assessment"). The course presents the latest research within
selected research areas on cell-cell communication and how
signaling pathways are integrated into higher order networks that
dictate the biological output of pathway activity. This will
provide knowledge into how aberrant regulation of cell signaling is
coupled to developmental disorders as well as diseases in the
adult.

Skills:

The course covers theoretical and experimental knowledge based
on text books, original articles and review papers such that the
student will be able to analyze, interpret and evaluate
experimental data obtained from cell biological research that
covers the criteria for exam assessment (please see "Criteria
for exam assessment").

Competences:

The student is competent to understand, interpret and integrate
the complexity of cellular communication and signaling processes in
cell biology.

Morning lectures are
followed by class teaching in the afternoon. Class teaching
includes discussions of the lectures of the day, description of
research techniques and methods, problem solving and discussions of
research data. Reviews and original papers from scientific journals
will accompany most lectures and class teaching.

Written open book exam. Exam problems will be handled out in
paper format, and you must answer the problems on special exam
paper, which is available at your desk and from the invigilators in
your exam room.

Aid

Only certain aids allowed

You are allowed to write your answers with pencil.

You are allowed to bring all aids in paper format.

You are allowed to bring your computer (either your laptop OR
your tablet). You are not allowed to bring more than one
computer.

Internet access and any form of communication with other
electronic devices are NOT allowed. Put your computer on ”flight
mode”.

Mobile phones, pocket calculators or any other electronic
devices (except your laptop or tablet) are NOT allowed.

NB: If the exam is held at the ITX, the ITX will provide
computers. Private computers, tablets or mobile phones CANNOT be
brought along to the exam. Books and notes should be brought on
paper or saved on a USB key.

Marking scale

7-point grading scale

Censorship form

External censorship

Re-exam

As ordinary exam.

If ten or fewer students have signed up for re-exam, the type of
assessment will be changed to oral exam 20 minutes with 20 minutes
preparation time. All aids allowed.

Criteria for exam assesment

In order to obtain the grade 12 the student should convincingly
and accurately demonstrate the knowledge, skills and competences
described under Learning Outcome.