Deuteronomy 28:35

The Lord shall smite thee in the knees, and in the legs, witha sore botch, that cannot be healed Which in those parts as it is very painful, so is not easily cured; and this which is threatened was incurable by the art of man, as others in ( Deuteronomy 28:27 ) ; and which should not stop there in the lower parts of the body, but proceed and spread:

from the sole of thy foot unto the top of thy head; and so be filled with them, as Job was with his boils and ulcers.