Thesis “Determination of cisplatin toxicity and the dose prognostication depending on the patient’s adipose tissue mass” is based on a clinical study. The hypothesis of study, that toxicity of cisplatin is prognostically related to the patient’s individual body fatty tissue mass amount and triglyceride level in blood serum. The study included 210 individuals, among them 172 cancer patients and a specially set up group of 38 healthy individuals to validate the study method. Methods. To analyze the human body parts different measurements were carried out with an emphasis on the adipose tissue mass. In addition, parameters such as body surface area (BSA), body mass index (BMI), body fat percentage (%) were determined. To prognose cisplatin toxicity, clearance was identified, using fluid chromatography and its correlation with triglyceride level in blood serum was researched.