In Hit The Road, Jack, stand-up comedian Jack Whitehall packs his bags and goes on a comedy tour of the country to find the best that Britain has to offer, joined along the way by celebrities and comedians who hail from each week's featured city. He arrives knowing no-one and without a place to lay his head, and so his first task is to find a random stranger willing to return to their home with Jack in tow. Thereafter he documents his experiences and the week reaches its climax in a high-octane show performed in a local venue temporarily transformed into an iconic studio.