Peroxisomes and their key role in cellular signaling and metabolism

Peroxisomes are a class of ubiquitous and dynamic single membrane-bounded cell organelles, devoid of DNA, with an essentially oxidative type of metabolism. In recent years it has become increasingly clear that peroxisomes are involved in a range of important cellular functions in almost all eukaryotic cells. In higher eukaryotes, including humans, peroxisomes catalyze ether phospholipids biosynthesis, fatty acid alpha-oxidation, glyoxylate detoxification, etc, and in humans peroxisomes are associated with several important genetic diseases.더 읽기…

상세정보

Peroxisome interactions and cross-talk with other subcellular compartments in animal cells --
Peroxisomes in human health and disease: metabolic pathways, metabolite transport, interplay with other organelles and signal transduction --
Aging, age-related diseases and peroxisomes --
Peroxisomes and the antiviral responses of mammalian cells --
Peroxisome proliferator-activated receptor-b signaling in hepatocarcinogenesis --
Involvement of human peroxisomes in biosynthesis and signaling of steroid and peptide hormones --
Peroxisome Ca2+ homeostasis in animal and plant cells --
The versatility of peroxisome function in filamentous fungi --
Essential roles of peroxisomally produced and metabolized biomolecules in regulating yeast longevity --
Metabolite transporters of the plant peroxisomal membrane --
known and unknown --
Peroxisomes and photomorphogenesis --
Biosynthesis of vitamin K1 (phylloquinone) by plant peroxisomes and its integration into signaling molecule synthesis pathways --
Role of peroxisomes as a source of reactive oxygen species (ROS) signaling molecules --
Peroxisomes as a source of auxin signaling molecules --
Peroxisomes as cell generators of reactive nitrogen species (RNS) signal molecules --
Role of plant peroxisomes in the production of jasmonic acid-based signals --
Role of plant peroxisomes in protection against herbivores --
Function of Peroxisomes in Plant-Pathogen Interactions.

초록:

Peroxisomes are a class of ubiquitous and dynamic single membrane-bounded cell organelles, devoid of DNA, with an essentially oxidative type of metabolism. In recent years it has become increasingly clear that peroxisomes are involved in a range of important cellular functions in almost all eukaryotic cells. In higher eukaryotes, including humans, peroxisomes catalyze ether phospholipids biosynthesis, fatty acid alpha-oxidation, glyoxylate detoxification, etc, and in humans peroxisomes are associated with several important genetic diseases.

"Peroxisome interactions and cross-talk with other subcellular compartments in animal cells -- Peroxisomes in human health and disease: metabolic pathways, metabolite transport, interplay with other organelles and signal transduction -- Aging, age-related diseases and peroxisomes -- Peroxisomes and the antiviral responses of mammalian cells -- Peroxisome proliferator-activated receptor-b signaling in hepatocarcinogenesis -- Involvement of human peroxisomes in biosynthesis and signaling of steroid and peptide hormones -- Peroxisome Ca2+ homeostasis in animal and plant cells -- The versatility of peroxisome function in filamentous fungi -- Essential roles of peroxisomally produced and metabolized biomolecules in regulating yeast longevity -- Metabolite transporters of the plant peroxisomal membrane -- known and unknown -- Peroxisomes and photomorphogenesis -- Biosynthesis of vitamin K1 (phylloquinone) by plant peroxisomes and its integration into signaling molecule synthesis pathways -- Role of peroxisomes as a source of reactive oxygen species (ROS) signaling molecules -- Peroxisomes as a source of auxin signaling molecules -- Peroxisomes as cell generators of reactive nitrogen species (RNS) signal molecules -- Role of plant peroxisomes in the production of jasmonic acid-based signals -- Role of plant peroxisomes in protection against herbivores -- Function of Peroxisomes in Plant-Pathogen Interactions."@en

"Peroxisomes are a class of ubiquitous and dynamic single membrane-bounded cell organelles, devoid of DNA, with an essentially oxidative type of metabolism. In recent years it has become increasingly clear that peroxisomes are involved in a range of important cellular functions in almost all eukaryotic cells. In higher eukaryotes, including humans, peroxisomes catalyze ether phospholipids biosynthesis, fatty acid alpha-oxidation, glyoxylate detoxification, etc, and in humans peroxisomes are associated with several important genetic diseases."@en