There was a general consensus among staff working at the medical clinic at the Manus Island detention centre that Iranian asylum seeker Hamid Khazaei needed to be provided with higher care, an inquest into his death has heard.

The 24-year-old was flown from Manus Island to the Pacific International Hospital in Port Moresby three days later, before being moved to Brisbane's Mater Hospital where he died from severe sepsis from an infected leg.

Queensland coroner Terry Ryan is investigating whether Mr Khazaei received appropriate medical care, and if the Australian Government and its contractors had adequate procedures in place to handle medical emergencies at offshore detention centres.

Day one of the inquest, being held at Brisbane Magistrates Court, heard from paramedic Rafael Cruz, who started working at the clinic in April 2014 and treated Mr Khazaei during two consecutive night shifts.

He told the inquest via video link at first Mr Khazaei presented as a routine patient as infections were common in the humid conditions on the island.

Mr Cruz said during the second night it was clear Mr Khazaei's health was deteriorating and that medical staff were having a hard time getting his blood pressure to a healthy level.

"There was a general consensus on day two he needed to be in a place that provided higher care," Mr Cruz said.