Clean-up is a part of the workflow in the production of hand-drawn animation, in which "clean" versions of the "rough" animation drawings are produced.

The first drawings are called "roughs" or "rough animation" because they are often done in a very loose fashion. If the animation is successfully pencil tested and approved by the director, clean versions of the drawings have to be done. In larger studios this task is given to the animator's assistant, or, in a more specialised setting, to a clean-up-artist. The artist doing the clean-ups is responsible for the final line and finished look of the shot.

Clean-ups generally are done on a new sheet of paper. They can be done on the same sheet as the rough animation if this was done with a "non-copy blue" pencil. This certain tone of blue will be invisible for photocopying machines or grayscale scanners, where the finished animation will be copied on cels or transferred into a computer for further processing.