Summary

This is a prospective randomized study of 114 patients. The purpose of this study is to
compare the efficacy of two standard methods of analgesia for pain control in patients
undergoing elective colon and rectal surgery, as measured by the Numeric Pain Scale (NPS)
and by the need for supplemental narcotic analgesics. This study is designed to determine if
postoperative pain control by local analgesics delivered through preperitoneally placed ON-Q
Silver SoakerTM catheters (CPA) is equivalent to continuous epidural analgesia (CEA).

Background Perioperative analgesia is a vital part of the management of patients undergoing
colon and rectal surgery, affecting well being and length of hospital stay. Neuraxial
anesthetics infused through epidural or spinal catheters have become commonplace pain
management agents for patients. These techniques, however, are labor-intensive and
expensive. Alternatively, local analgesics may be administered directly to the surgical
wound via silver catheters.
Aim Two standard methods of analgesia for pain control for colon and rectal surgery will be
evaluated systematically to determine if these two approaches are equivalent in terms of
patient pain scores and supplemental narcotic use.
Study Design This is a prospective randomized study of 114 participants undergoing elective
colon and rectal surgery at an independent academic medical center. The primary outcomes
are post-operative pain control and supplemental narcotic usage.
Other variables of interest
- Surgical site infections
- The post-operative time to return of bowel function
- The hospital expenses/cost differences
- Quality of life measured with the SF- 36 questionnaire