He has already started the first of his five marathons, which by the end of the five days will take him all the way to the historic city of Petra.

In a video he posted on social media the 31-year-old said the weather was cooler than he expected and made for perfect running conditions.

Jaguar Land Rover worker Andrew, from Halewood, helped to raise £50,000 for the Anthony Nolan Trust last year with his 10,000-mile cycle ride from Shanghai to Liverpool.

He won an ECHO Pride of Merseyside Award, and was also presented with an award at the House of Commons after he was named Individual Fundraiser of the Year by the Anthony Nolan charity, which manages the country’s bone marrow donor register.

Andrew was inspired to take on his daring challenges when a work colleague’s four-year-old son, Charlie Fearns, was diagnosed with leukaemia and in desperate need of a life-saving bone marrow transplant.

Anthony Nolan charity spokeswoman Jackie Graveney said: “We’re delighted that Andrew has been inspired to take on another incredible fundraising challenge for Anthony Nolan, the charity that saves the lives of people with blood cancer by matching people willing to donate their stem cells.

“Last year, Andrew cycled a staggering 10,000 miles from China to Liverpool which helped to raise a fantastic £50,000 for Anthony Nolan. Now, he’s pushing himself even further by taking on five marathons in five days.

“We need more people to join our register, but it also costs us £60 to recruit and process each new donor. Andrew’s ‘Running Scouser’ challenge will allow us to add more people to our register, ultimately providing more matches and saving more lives.”

Anyone who wants to donate to Andrew’s latest challenge should visit justgiving.com/runningscouser. You can join the Anthony Nolan bone marrow register at www.anthonynolan.org