Combat

Going the all out on lethality can reward you with some intense firefights, especially later in game where guards can activate alarms which in turn release the security bots. Not to mention that some of your adversaries are also augmented with stealth capabilities, requiring you to buy the wall penetration imaging augmentation. This will show you where exactly they are in the environment, and with the Mark & Track upgrades you can keep track of them without wasting energy on maintaining the wall penetration augmentation.

Combat Tips

Use cover! If it isn't obvious by now, use cover to your advantage. Not only does it protect you from the spray of bullets coming your way, but combined with the stealth augmentation can provide with some excellent flanking maneuvers

Upgrades! look for weapons upgrades or buy them if you really need to, they just might give you the advantage you need for battle against regular enemies and the boss battles ahead. And remember to focus on upgrades that would help you not only offensively, like Recoil Reduction, but also defensively such as Dermal Plating

The brute force approach, favored by some, is chiefly about killing first, and looting the corpses for personal secretaries and items later. That said, opt for long ranged sniper tactics, and perhaps a combat rifle (or shotgun) for back-up.

You can also try to find a more advantageous position by looking around before going in guns blazing. This will ensure that you can take out the most enemies whilst taking the least amount of damage.

Carry around other weapons along with extra ammo, you never know what upgrades you may find for your extra weapons or what kind of situation you would need it for

HEADSHOTS!!! The only way to pick off enemies undetected from a distance is with a headshot from a silenced weapon, it is recomended that you do this while peeking from cover with a laser sight attached to the weapon, the 10mm pistol and combat rifle are great at this. Be advised that some enemies wear helmets and can take multiple shots to the head before death.