Ryan Reynolds – who recently ran the New York City Marathon in honor of his father, who suffers from Parkinson's – also attended the star-studded event, along with his new wife Scarlett Johansson. Also on the guest list: Rachael Ray, Julianne Moore, Ben Stiller and New York Yankee Derek Jeter.

The event was even more celebratory than usual, thanks to Barack Obama's presidential win the night before.

"I'm positive that one of the first things that [Obama] is going to do ... is revisit the [George W. Bush's] ban on stem cell research ...," Fox told PEOPLE at the event, which he attended along with wife Tracy Pollan and daughters, Schuyler and Aquinnah. "I'm really excited."