Over twenty years of research experience in biostatistics, with rich experience of medical statistical work and strong data processing ability, Based on grasping the theory and method of, medical statistics and epidemiology, familiar with and attention mathematical statistics, geographical epidemiology, geological statistics, geographic information system and other disciplines, enhance innovation consciousness, pay attention to interdisciplinary in the research topic, after many years of efforts, has formed its unique research direction - Spatial Epidemiology and Spatial Statistics theory and method research and it’s application. Research results enrich and develop the spatial epidemiology and statistical analysis method.