The aim of the research is to determine the possible application of Acacia polycantha in the treatment
of sexual behavior and serum testosterone. We determined the LD50 from the dried bark of the plant to be
3808.88 kg/body weight, then treated the wistar rats with 150, 300 and 600 mg/kg body weight that was shown
to have effects on mounting behavior which increased from 6.20±2.49 in control to up to 8.40±3.25 with
concentration of 150 mg/kg and falls to 3.80±1.35 and 0.20+0.20 with 300 and 600 mg/kg body weight
respectively. On the other hand the testosterone levels increased from 3.62±2.19 in control to 6.88±1.78 with
150 mb/kg and 7.18±2.38 and 7.78±2.38 with 300 and 600 mg/kg respectively while falling insignificantly
below the control to 3.60±1.34 with Viagra 150 mg/kg. We concluded therefore based on the experiment
conducted that Acacacia polycantha plant could be used to enhance sexual behavior after further screening of
its active ingredients.