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This pre-Warchem was created by Med-Tek. They were designed to increase memory related functions and speed up other mental processes. These chalky red pills were a popular party drug once favored for the boost it gave to creativity - turn on, tune in, drop out.[1]

After the war, the Professor allegedly developed an easy method to mass-produce Mentats, likely owing to its ubiquitous nature across the country, even years after the war had already ended.

Mentats were sold in both cardboard and tin packaging, the latter a bit more likely to survive the nuclear holocaust. They are, of course, highly addictive, with regular Mentats at a 5% chance of addiction, and Party Time Mentats at a whopping 15% addiction chance.

The name Mentats is a reference to Frank Herbert's Dune, where, in the wake of humanity rejecting artificially intelligent computers and robots, Mentats are humans trained for computer-like mathematical and logical computations. Also of note is that the pills are colored red. Red-stained lips are a distinguishing characteristic of a Dune Mentat.