A senior police officer from the Tweed-Byron Local Area Command says it's one of the worst areas in the state for alcohol-related crime.

There are renewed concerns about the issue after two men, aged 42 and 50, were punched in separate incidents on the Tweed coast this month.

Both died in hospital yesterday, prompting police to lay murder charges.

Superintendent Stuart Wilkins says the problem is being brought under control in other commands across the state.

"We have 12 commands in the north region here, 11 of them are under target for alcohol-related crime and reducing it," he said.

"We've actually had some good success since January in reducing alcohol-related crime but without question, I don't flip it off at all, it is an issue for us and particularly for the culture within this command.

"We address it every day of the week, every night of the week we do significant business inspections on licensed business premises.

"We have extra patrols in the Byron Bay and Tweed Heads areas for alcohol-related assaults and alcohol-related crime.

"People that know me from this area know that I've been bleating on about alcohol-related assaults and violence for some time.

"We are absolutely in close collaboration with the licensed premises and they absolutely know what the expectation is upon them and we have a very healthy relationship with them.

"It's also about time people took some personal responsibility for themselves, I think."

Meanwhile, the state member for Tweed says problems with alcohol in the area also extend to local roads.

Geoff Provest says he's often shocked by the reports he receives about booze-fuelled behaviour.

"Tweed notoriously has a badge of shame," he said.

"For many years we've suffered the highest level of drink driving per head of population than anywhere else in NSW.

"I think a lot more can be done with it.

"There is no silver bullet to this... there is a cultural problem here within the Tweed."