Radiology

Research + Clinical Trials

As part of a major academic medical center, the Radiology Department considers research to be an important part of its mission. Our radiologists are regularly exploring innovative new uses of imaging technologies. They also actively collaborate with Tufts MC colleagues who are conducting clinical research on a variety of diseases with an imaging component, including osteoarthritis and fatty liver disease.

Faculty Scholarly Activities

Recently completed or on-going research projects being conducted by members of the Department:

Do-Dai, D: Co-P.I. - A Multi-Center, Double-Blind, Randomized Study Comparing the Combined use of Interferon Beta-1a and Glatiramer Acetate to Either Agent Alone in Patients with Relapsing Remitting Multiple Sclerosis (CombiRx-Phase III). PI: Jeffrey Chavin, MD. This trial is not yet open, but has IRB approval.

Do-Dai, D: Co-P.I. - A Phase III, Randomised, Parallel Group, Multi-Centre Study in Recurrent, Glioblastoma Subjects to Compare the Efficacy of AZD2171 [RECENTIN(tm)], Monotherapy and the Combination of AZD2171 with Lomustine to the Efficacy of Lomustine Alone. PI: Jay-Jiguang Zhu, MD, PhD. This trial has been postponed until summer 2008.

Do-Dai, D: AstraZenica-AZD2171: A Phase III, Randomised, Parallel Group, Multi-Centre Study in Recurrent Glioblastoma Patients to Compare the Efficacy of Cediranib [RECENTIN™, AZD2171] Monotherapy and the Combination of Cediranib with Lomustine to the Efficacy of Lomustine Alone.

Do-Dai, D: NovoCure-EF14: A Prospective, Multi-center Trial of NovoTTF-110A Together with Temozolomide Compared to Temozolomide Alone in Patients with Newly Diagnosed Glioblastoma Multiforme

Do-Dai, D: Myriad-MPC-6827: A Phase II Study of Azixa™ (MPC-6827) for the Treatment of Patients with Glioblastoma Multiforme or Anaplastic Gliomas in First Relapse

Tedesco K, Bhadelia R. Association between Fractional Anisotropy in the Corpus Callosum and Quantitative Measures of Gait and Balance in Elderly Individuals. January 2006 Presented as a scientific paper at the 45th Annual Meeting of the American Society of Neuroradiology (June 2007).

Tedesco K, Bhadelia R. Increased Cochlear Signal on FLAIR Images in Patients with Acoustic Neuroma: A Manifestation of High Protein Levels in Perilymph. November 2006. Presented as a scientific paper at the 45th Annual Meeting of the American Society of Neuroradiology (June 2007).