Go into central administration - Application Management - Configure Alternate Access Mappings, select the appropriate web application and add http://10.0.45.62:16191 as one of the Public Urls for the web app. That will tell SharePoint to respond to those requests.

You may need to add that to the web application directly in IIS as well.

Found my problem. Its such a newbie thing I dont even want to mention it.... I created the subsite as part of SharepointCentral - not as a site on its own under Sharepoint-80. Thats the reason for all the issues. Thanks to Dave and 1c1cle for trying to help!