Direct assessment of myelin would reveal central nervous
system (CNS) abnormalities and enhance our understanding
of neurological diseases. Our previous work demonstrated
that myelin can be directly imaged on a 9.4T NMR
laboratory spectrometer/imaging system with ultra-short
echo time (UTE) imaging. However, the extremely short T2
values (~100s) and relatively low proton density of
myelin limit its detectability on clinical scanner. In
this work, we demonstrate the feasibility of
quantitative zero-echo time (ZTE) imaging of
reconstituted extracted myelin and intact lamb spinal
cord at 9.4T and on a 3T whole-body scanner.

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