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March 13, 1987
SP97
Patricia Martin, Director
CARLETON STUDENTS, FACULTY DO GENE RESEARCH
Northfield, Minn.—Few college students get a chance to do significant
hands-on scientific research and to see the results published in science
journals. But at Carleton College, John Tymoczko involves students in
his study of how genes are regulated.
Tymoczko, professor of biology and chair of the department, combines
teaching and research. For the past six years, he has been working on a
project to understand how a group of hormones regulate gene activity.
Genes carry the information which decides how the chemicals we are
made of are put together. Tymoczko is interested in the genes in liver
cells, and how they are affected by glucocorticoids.
Glucocorticoids are hormones which can regulate gene activity. In
plain English, they can turn genes on and off. By looking at this
mechanism of control in rat livers, Tymoczko hopes to learn how
glucocorticoids affect the way genes work.
Most people would probably think that the isolation and purification
of a steroid receptor from rat livers would be an obscure and pointless
task, but now that many cancers are known to be "in the genes," the
results of this research may have far-reaching implications. They may
show how our bodies control the way cancer genes operate. "Some cancers
are stimulated by glucocorticoid steroids and others are unaffected by
them," Tymoczko explains. The research, he says "will help us understand
how certain cancers can be stopped from growing."
To help him with the project, Tymoczko has enlisted the assistance
of Carleton students. Both Alison Unger (a 1985 graduate from Chagrin
Falls, Ohio) and Georgia Ede (a 1986 graduate from Newburyport, Mass.)
majored in biology at Carleton. Now they work for Tymoczko as full-time
lab technicians.
In addition, two Carleton seniors, Ravindra Uppaluri (Brooklyn Park,
Minn.) and Shawn Ahern (Tnver Grove Heights, Minn.), are helping Tymoczko
with the research by doing independent study through the Honor's Program
in Biology.
(more)

March 13, 1987
SP97
Patricia Martin, Director
CARLETON STUDENTS, FACULTY DO GENE RESEARCH
Northfield, Minn.—Few college students get a chance to do significant
hands-on scientific research and to see the results published in science
journals. But at Carleton College, John Tymoczko involves students in
his study of how genes are regulated.
Tymoczko, professor of biology and chair of the department, combines
teaching and research. For the past six years, he has been working on a
project to understand how a group of hormones regulate gene activity.
Genes carry the information which decides how the chemicals we are
made of are put together. Tymoczko is interested in the genes in liver
cells, and how they are affected by glucocorticoids.
Glucocorticoids are hormones which can regulate gene activity. In
plain English, they can turn genes on and off. By looking at this
mechanism of control in rat livers, Tymoczko hopes to learn how
glucocorticoids affect the way genes work.
Most people would probably think that the isolation and purification
of a steroid receptor from rat livers would be an obscure and pointless
task, but now that many cancers are known to be "in the genes," the
results of this research may have far-reaching implications. They may
show how our bodies control the way cancer genes operate. "Some cancers
are stimulated by glucocorticoid steroids and others are unaffected by
them," Tymoczko explains. The research, he says "will help us understand
how certain cancers can be stopped from growing."
To help him with the project, Tymoczko has enlisted the assistance
of Carleton students. Both Alison Unger (a 1985 graduate from Chagrin
Falls, Ohio) and Georgia Ede (a 1986 graduate from Newburyport, Mass.)
majored in biology at Carleton. Now they work for Tymoczko as full-time
lab technicians.
In addition, two Carleton seniors, Ravindra Uppaluri (Brooklyn Park,
Minn.) and Shawn Ahern (Tnver Grove Heights, Minn.), are helping Tymoczko
with the research by doing independent study through the Honor's Program
in Biology.
(more)