The advanced intermediates in the syntheses of tetrodotoxin reported by Fukuyama, Alonso,
and Sato were prepared. The key steps in the synthesis of the title compounds involved the toluene dioxygenase–mediated dihydroxylation ...

A total synthesis of the fungal-derived natural prod-uct pestynol is reported via a convergent chemoenzymatic ap-proach from the readily available precursors geranyl bromide,ethyl acetoacetate, trimethylsilylacetylene, and ...

Immobilized lipase B from Candida antarctica (Novozym® 435, N435) was utilized as part of a
chemoenzymatic strategy for the synthesis of branched polyesters based on a cyclotetrasiloxane core in
the absence of solvent. ...

An efficient protocol for the isolation of narciclasine from common Amaryllidaceae bulbs, separation from haemanthamine, and the occurrence of a trace alkaloid, 2-epi-narciclasine are reported. Attempts to convert natural ...

The base-catalyzed condensation reaction between (E)-4-phenylbut-2-enal and phenylpropargyl aldehyde recently reported in the literature to provide formylcyclobutadiene was repeated under the published conditions. The ...