DCE measurements are able to detect, quantify and
monitor tumor response on anti-angiogenic agents by assessing changes in the
contrast agents permeability of the tumor vascular system. Especially DCE
experiments in mice can help to better verify effects of anti-angiogenic drugs
on tumors. Unfortunately, the design and setup of DCE experiments in small
animals are reported only fragmentally. However, a reasonable setup is crucial
to conduct reliable DCE experiments. The purpose of this work was to report in
detail the design and setup of DCE experiments of our institution to monitor
treatment of anti-angiogenic drugs in tumor bearing mice.