An international collaborative study led by the University of Strasbourg has demonstrated a novel way how chronic hepatitis C infection can be cured. Instead of attacking the virus itself, the scientists target a liver protein which serves as a door for the virus entry into the cell. A humanized mouse model developed in the lab of Prof. Maura Dandri (also head of SFB 841 project A5) was used to succesfully test the new therapeutic approach in human liver cells.