Other factors that may be responsible for the decline in the prevalence of duodenal ulcer over the study period should be considered because of the unexpected difference in the changing prevalence patterns of duodenal ulcer and gastric ulcer.

Hence by their ability to differentiate into gastric cells and their ability to increase growth factors EGF & VEGF as well as reducing inflammatory mediators, stem cells have shown potential efficacy in treating gastric ulcer, where their effect was as good as that of omeprazole.

It included 80 healthy subjects and the studied population was divided on the basis of (a) eating food from outside home daily, twice a week or once a week, (b) using filtered or tap water for drinking, and (c) having family history of gastric ulcer or without family history of gastric ulcer.

These agents have been implicated in the pathogenesis of gastric ulcer including enhanced gastric acid and pepsin secretion, inhibition of prostaglandin synthesis and cell proliferation growth, diminished gastric blood flow and gastric motility (7)

Prevacid NapraPAC (lansoprazole delayed-release capsules and naproxen tablets kit) is now approved for reduction of NSAID-associated gastric ulcers in patients with a history of a documented gastric ulcer who require the use of an NSAID for the treatment of the signs and symptoms of rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.

Cytotec is indicated for the prevention of NSAID (nonsteroidal anti-inflammatory drugs)-induced gastric ulcers in patients at high risk of complications from gastric ulcer, as well as patients at high risk of developing gastric ulceration, such as patients with a history of ulcer.

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