This article explores how relevant the “Responsibility to Protect” (RtoP) principle is in Southeast Asia. Southeast Asia is usually thought of as a region that is highly resistant to external “interference” in its domestic affairs and relatively impervious to the influence of externally generated norms. The article explores the potential relevance of RtoP through an analysis of the impact of Cyclone Nargis on Myanmar. Although the military regime in Myanmar was initially resistant to external intervention, pressure from both the United Nations and especially fellow members of the Association of Southeast Asian Nations (ASEAN) caused the regime to change its behavior. The authors argue that this marks an important shift in intra-ASEAN relations and suggests that even in Southeast Asia where sovereignty is still jealously guarded, external norms and ideas can have a decisive impact in propitious circumstances.