2018-05-24T21:52:18Zhttp://herbmed.skums.ac.ir/?_action=export&rf=summon&issue=34752016-02-01Advanced Herbal MedicineAdv Herb Med201621Qualitative and quantitative changes of essential composition in the flowers of some populations of Elaeagnus angustifoliaFaranakElmiGholamrezaDehghanBehnamBeigzadehBackground and aims: Elaeagnus angustifolia L. is a member of the Elaeagaceae family; different parts of it, especially fruits have been used for the treatment of several diseases in traditional medicine. The aim of this study was to isolate and determine essential oil composition of flowers of E. angustifolia collected from different ecological areas of East-Azarnayjan in Iran. Methods: In this experimental study, the essential oils of the flower were isolated by hydrodistillation method and analyzed by GC and GC/MS. Results: The number of compounds in the essential oil isolated from the population of Ahar, Marand and Hashtroud were 22, 17 and 14, respectively. The major component of all of the populations was ethylcinnamate; Ahar (47.59%), Marand (69.99%) and Hashtroud (85.49%). It was observed that the oil number of E. angustifolia decreases from 22 to 14 when the altitude increases from 1344-1750 m. Conclusion:Chemical composition of the essential oils of E. angustifolia L. such as esters and aromatic acids contents were increased while the ketone content was decreased with increasing altitude.Elaeagnus angustifoliaEssential oilsGC/MSEstersKetones2016020116http://herbmed.skums.ac.ir/article_20785_77aee565bcd873773ee056b2dda22fc7.pdf2016-02-01Advanced Herbal MedicineAdv Herb Med201621Comparison of protective effects of omega3 fish oil and aqueous extract of Glycyrrhiza glabra root on biochemical factors and liver tissue changes induced by thioacetamide in male ratsDavoodMoghadamniaMokhtarMokhtariSaeedKhatamsazBackground and aims: Thioacetamide can lead to liver cirrhosis and hepatocarcinoma. This study was aimed to evaluate the ability of omega3 fish oil and Glycyrrhiza glabra aqueous extract to attenuate biochemical factors and liver tissue changes induced by thioacetamide.
Methods: In this experimental study, 63 wistar male rats were divided into 9 groups. Control group, Sham group received 0.4ml olive oil orally per day for 3 months. Thioacetamide group received 150 mg/kg of TAA intraperitoneally in a single dose for 3 months. Experimental groups 1, 2, 3, 4, 5 and 6 received 100, 200, 300 mg/kg of omega3 fish oil and aqueous extract of Glycyrrhiza glabra root orally per day for 3 months and 150 mg/kg of TAA intraperitoneally in a single dose for 3 months. The provided blood samples were tested for serum levels of bilirubin, albumin, and total protein. The pathological examination of hepatic tissue samples was done after hematoxylin and eosin staining.
Results: Treatment with 100 mg/kg of omega3 fish oil (0.06±0.013) significant reduced the serum level of billirubin comparing with thioacetamide group (0.38±0.015). Treatment with the aqueous extract of Glycyrrhiza glabra root at all doses (0.37±0.034) (0.34±0.027) (0.15±0.028) showed no significant difference in the serum level of billirubin comparing with thioacetamide group (0.38±0.015). Treatment with the omega3 fish oil (4.40±0.02) (4.32±0.10) (4.34±0.10) and aqueous extract of Glycyrrhiza glabra root at all doses (4.33±0.06) (4.31±0.5) (4.20±0.07) significant reduced the serum level of albumin comparing with thioacetamide group (4.70±0.00). The mean levels of total protein showed no significant difference in the experimental groups (8.77±0.31) (8.53±0.20) (8.63±0.24) (8.58±0.05) (8.57±0.10) (7.92±0.21) comparing with thioacetamide group (8.56±0.08). In all experimental groups, the hepatic tissue changes induced by thioacetamide improved which were dose dependent (PGlycyrrhiza glabra rootOmega3 fish oilThioacetamidebiochemical factorsRat20160201719http://herbmed.skums.ac.ir/article_20787_75b8037b93680fc27e1ba55f5c3fb837.pdf2016-02-01Advanced Herbal MedicineAdv Herb Med201621Antibacterial and ciprofloxacin -potentiation activities of Berberis vulgaris L. root extracts against some gram-negative pathogenic bacteriaAzizollahEbrahimiBaharehMoazamiMohamad RezaMahzooniehShararehLotfalianBackground and aims: Some medicinal plants particularly those with antimicrobial properties contain compounds that potentiate the activity of antimicrobials against pathogenic bacteria. This study was planned to search the antibacterial activities of the hydro alcoholic and chloroform extracts of Berberis vulgaris L.root and their synergistic effects with ciprofloxacin against some gram-negative pathogenic bacteria.
Methods: After grinding, powder of Berberis vulgaris L. roots were extracted with ethanol 85% and chloroform by maceration method. Broth micro dilution method was used for determination of minimum inhibitory concentrations (MICs) of the extracts alone or in association with ciprofloxacin and Phenylalanine-Arginine β- Naphtylamide (PAβN) as a positive control and efflux pumps inhibitor (EPI).
Results: MIC determination indicated that the hydro alcoholic and chloroform extracts from Berberis vulgaris L. rootwere able to inhibit the growth of all the studied bacteria within a concentration range of 25000 to 75000 and 1562 to 6250 µg/mL, respectively. Synergistic effects were noted between the extracts from Berberis vulgaris L.root extracts and ciprofloxacin on all tested bacteria.
Conclusion: Berberis vulgaris L. root extracts act as an antibacterial agent and potentiate ciprofloxacin effects on examined pathogenic bacteria. The present investigation brings about primary information’s for the possible use of these extracts in association with fluoroquinolones.Antibacterial activitiesBerberis vulgaris LGram-negative bacteria201602012025http://herbmed.skums.ac.ir/article_20789_fd48d42b4fc46784f24c652ef8fc7c22.pdf2016-02-01Advanced Herbal MedicineAdv Herb Med201621Antimicrobial activities of Gold nanoparticles against Salmonella typhimuriumFarzanehGhanavati BehbahanMohammadSalariSeyedeh RazeyehMousaviRazeyehRezaeiBackground and aims: One of the major problems in hospitals is resistant pathogenic bacteria to antimicrobial substances. The problem of increased costs of treatment failure and mortality rates is increasing.The aim of this study was to evaluate the antimicrobial activity of gold nanoparticles has been on Salmonella typhimurium. Methods: This cross-sectional study was performed and Salmonella typhimurium bacteria were isolated from poultry.Gold nanoparticles for business were purchased. Minimum inhibitory concentrations of gold nanoparticles in different concentrations by dilution in the wells were determined on bacteria. Susceptibility to several antibiotics was evaluated by Kirby-Bauer disk diffusion method. Results: The result of gold nanoparticles showed the highest MIC (the minimum inhibitory concentration) was 100 ppm concentration that 6 strains of them were inhibited by this concentration. The lowest MIC was 50 ppm concentration that 1 strain of Salmonella was inhibited. The highest and lowest MBC value of extractwas 200 and 100 ppm, respectively. Conclusions: The results showed that gold nanoparticles have good inhibitory effect on all studied bacteria.Gold nanoparticlesAntibacterial activitySalmonella typhimurium201602012630http://herbmed.skums.ac.ir/article_20779_6129e665ec7d9524fbcd165e84b509eb.pdf2016-02-01Advanced Herbal MedicineAdv Herb Med201621Antifungal effects of the extract of the Withania somnifera on Candida albicansFereshtehJavadianZahraSepehriSaeidehSaeidiMehdiHassanshahianBackground and aims: Withania somnifera (W. somnifera), commonly known as Ashwagandha, is an important medicinal plant that has been used in Ayurvedic and indigenous medicine for over 3,000 years. Candidiasis is one of the most common opportunistic fungal diseases in humans. In fact, the most important fungal disease in women is vaginal candidiasis. This study aimed to investigate the antifungal effects of the extracts of the W. somnifera on Candida albicans (C. albicans). Methods: In this experimental research, 9 vaginal samples were collected using the sterile swap and Falcon tube by the gynecological specialists. The extracts of the shallot and artichoke were prepared using a rotary device. The inhibitory concentration against C. albicans was determined using incubation in media. Results: The results of this study suggested that the minimum inhibitory concentration (MIC) against C. albicans, which is equivalent 50 ppm to 250 ppm has the highest concentration of inhibitor. Conclusion: The results of this study showed that the antifungal activity of wind cheese against C. albicans is good, so it can be used as a drug to treat infections caused by C. albicans.Extract plantWithania somniferaCandida albicansAntifungal effects201602013137http://herbmed.skums.ac.ir/article_20790_05b0fd0e1c19d18469cbef8f08151982.pdf2016-02-01Advanced Herbal MedicineAdv Herb Med201621Antifungal effects of the extracts of the shallots and artichokes on Candida albicansMohammad AminMashhadiBarat AliFakheriSaeidehSaeidiBackground and aims: Over the recent decades, the infections caused by the opportunistic fungus including the Candida albicans (C. albicans) have increased, thereby causing the high rate of diseases. With respect to the limitations of the treatment of the fungal infections and expensive antifungal drugs, researchers have been increasingly interested in finding anti-fungal drugs. This study aims to investigate the antifungal effects of the extracts of the shallots and artichokes on C. albicans. Methods: In this experimental research, the extracts of the shallot and artichoke were prepared using a rotary device. The inhibitory concentration against C. albicans was determined using incubation in media. Results: The results of the study showed that increased concentration of the extract increased the antifungal effects. The extract of the artichoke had higher inhibitory effect compared to the extract of the shallot. Moreover, as the extract was decreased the size of the fungi colony was increased. Conclusion: The results of the study showed that extracts of the shallots and artichoke were proper inhibitors for the C. albicans and it is hoped that herbal medicines and possibly new compounds for treatment of the fungal infections be discovered in future.Antifungal activityShallotArtichokeCandida albicans201602013843http://herbmed.skums.ac.ir/article_20791_949d19876709f2c6eae3649f6d193feb.pdf2016-02-01Advanced Herbal MedicineAdv Herb Med201621A review on the medical effects of Capparis spinosa L.RaminRahnavardNastaranRazaviBackground and aims: Plants are a valuable source of wide range of secondary metabolites. Caper (Capparis spinosa L.) belongs to the Capparaceae family. It has a lot of medical uses especially in medical fields. The aim of this study is to review the medical uses of this plant in nobel studies. Methods: In order to conduct this review study, INLM and Google scholar and Science direct databases were searched for English published articles during 2000-2015. Results: This plant has a lot of traditional and medical use. The whole plant was used for rheumatism. Roots were used as diuretic, astringent, and tonic. Bark root, which has a bitter taste, was used as appetizer, astringent, tonic, ant diarrheic and to treat hemorrhoids and spleen disease. Bark was also used for gout and rheumatism, as expectorant, and for chest diseases. Infusion of stems and root bark were used as anti-diarrheic and febrifuge. Fresh fruits were used in sciatica, and dropsy. Dried and powdered fruit combined with honey was used in colds, rheumatism, gout, sciatica and backache. Seeds were used in feminine sterility and dysmenorrheal and to relieve toothache. Crushed seeds were used for ulcers, scrofula, and ganglions. Conclusion: The paper reviewed was promising medicinal plant with wide range of pharmacological activities which could be utilized in several medical applications because of its effectiveness and safety.Capparis spinose LINLMGoogle scholarScience directMedical uses201602014453http://herbmed.skums.ac.ir/article_20857_00a5e7232f142c8d3dd08855a4c8dc19.pdf2016-02-01Advanced Herbal MedicineAdv Herb Med201621Herbal medicine in pregnancyMahdiehJaafariAsiehFotoohiNastaranRazaviAmirAbdian AslBackground and aims: Herbal medicines are derived from natural plants with medicinal or preventive properties. Use of herbal remedies has increased despite lack of scientific evidence about their efficacy and safety during pregnancy. Methods: This is an internet-based study. In this mini review, a publication search was conducted in the Medline, Google Scholar, and EMBASE databases, using a combination of medical subject headings (MeSH) and Black cohosh, Ginseng, Red Raspberry, Aloe vera, Chamomile, Chasteberry and Garlic keywords. The MeSH terms included herbal medicine, herbal products, pregnancy, and pregnant women. Results: Herbal remedies are very common. Some information will list an herb as safe to consume during pregnancy, whereas another source may list the same herb as unsafe depending on the source. Although herbs are natural, not all herbs are safe to take during pregnancy. Conclusion: Medicinal herbs can be very useful and effective during pregnancy. Despite the beneficial effects of herbs during pregnancy, use of certain herbal and traditional medicines without prior consultation with a health care professional may be harmful for pregnant women and their babies.Herbal MedicinePregnancyMedline201602015466http://herbmed.skums.ac.ir/article_20885_40223f69dbfb6dcc0cd295fa1c0e92d9.pdf