Record number of patients take part in clinical research(National Institute for Health Research) Over 870,000 participants involved in health and social care research across England -- a huge increase. The number of new life sciences studies supported by the National Institute for Health Research (NIHR) the highest yet. (Source: EurekAlert! - Cancer)Source: EurekAlert! - Cancer - May 19, 2019 Category: Cancer & Oncology Source Type: news

Largest study of sickness in pregnancy launches(NIHR Biomedical Research Centre at Guy  s and St Thomas  and King  s College London) Women with severe sickness during pregnancy are being invited to join the largest study of the condition in Europe, led by Guy's and St Thomas' NHS Foundation Trust and King's College London. (Source: EurekAlert! - Medicine and Health)Source: EurekAlert! - Medicine and Health - May 16, 2019 Category: International Medicine & Public Health Source Type: news

Test yourself against real surgeons in a giant game of OperationSurgeons from the National Institute for Health Research (NIHR) will be challenging passers-by to a giant game of Operation in Clifton Down Shopping Centre on 20 May to mark International Clinical Trials Day. (Source: University of Bristol news)Source: University of Bristol news - May 15, 2019 Category: Universities & Medical Training Tags: Health, Public engagement; Faculty of Health Sciences, Faculty of Health Sciences, Bristol Medical School, Institutes, Bristol Population Health Science Institute, Faculty of Health Sciences, Translational Health Sciences, Faculty of Health Sciences, Popu Source Type: news

Faster walkers more likely to live longer(National Institute for Health Research) People who report that they have a slower walking pace have a lower life expectancy than fast walkers, according to a new study conducted by researchers at the National Institute for Health Research (NIHR) Leicester Biomedical Research Centre -- a partnership between Leicester's Hospitals, the University of Leicester and Loughborough University. (Source: EurekAlert! - Social and Behavioral Science)Source: EurekAlert! - Social and Behavioral Science - May 15, 2019 Category: International Medicine & Public Health Source Type: news

Drug combination could be effective for treatment-resistant gonorrhea(National Institute for Health Research) Scientists comparing treatments for gonorrhea have identified a drug combination that could be an effective back-up for patients not responding to current therapy. The research team, from University Hospitals Birmingham, found that a treatment of the antibiotic gentamicin with azithromycin worked almost as well as the currently used ceftriaxone for genital gonorrhea. (Source: EurekAlert! - Infectious and Emerging Diseases)Source: EurekAlert! - Infectious and Emerging Diseases - May 2, 2019 Category: Infectious Diseases Source Type: news

Tackling antimicrobial resistance (AMR):A new campaign by the National Institute for Health Research (NIHR) is shining a light on the threat of antimicrobial resistance (AMR) and the research response required. The UK government's goal is to contain and control antimicrobial resistance by 2040. (Source: Current Awareness Service for Health (CASH))Source: Current Awareness Service for Health (CASH) - April 5, 2019 Category: Consumer Health News Source Type: news

‘ Overcoming Barriers: Autism in the Somali community ’ film premiereWorld Autism Awareness Day (WAAD) is an internationally recognised day on 2 April every year to raise awareness of the hurdles that people with autism – and others living with autism – face every day. Following research by the University of Bristol, the National Institute for Health Research (NIHR) and Autism Independence, a film that tells the stories of Bristol-based Somali families affected by autism and the professionals who support them will be premiered tomorrow [Wednesday 3 April]. (Source: University of Bristol news)Source: University of Bristol news - April 2, 2019 Category: Universities & Medical Training Tags: Health, Research; Faculty of Health Sciences, Faculty of Health Sciences, Population Health Sciences; Press Release Source Type: news

Surgery using ultrasound energy found to treat high blood pressure(Queen Mary University of London) A one-off operation that targets the nerves connected to the kidney has been found to maintain reduced blood pressure in hypertension patients for at least six months, according to the results of a clinical trial led in the UK by Queen Mary University of London and Barts Health NHS Trust, and supported by the National Institute for Health Research (NIHR). (Source: EurekAlert! - Medicine and Health)Source: EurekAlert! - Medicine and Health - March 18, 2019 Category: International Medicine & Public Health Source Type: news

Cochrane-REWARD prize - 2017 Award Winner: SYRCLEWhen it received the joint second Cochrane-REWARD prize in 2017,SYRCLE (the SYstematic Review Center for Laboratory animal Experimentation) was focused on encouraging the use of systematic reviews of animal studies to reduce waste and improve quality. Since then, SYRCLE has evolved, and here Merel Ritskes-Hoitinga gives an overview of how things have developed.SYRCLE started in the Netherlands with the aim of improving the reliability of laboratory animal research and its relevance for patients by using systematic reviews. Systematic reviews have not been commonly used for animal studies, yet we saw the potential of implem...Source: Cochrane News and Events - March 13, 2019 Category: Information Technology Authors: Muriah Umoquit Source Type: news

No additional weight-loss reported from a lifestyle programme for people with psychosisPeople with schizophrenia are twice as likely to be overweight as the general population, as medication side effects frequently include weight gain. This NIHR-funded study with over 400 participants in 10 areas across England is the largest UK randomised trial to date.
It shows that this hard-to-reach group can be recruited and retained in structured self-management programmes delivered by trained facilitators. However, it was neither clinically effective nor cost-effective.
Alternative, affordable approaches are much needed. (Source: Current Awareness Service for Health (CASH))Source: Current Awareness Service for Health (CASH) - February 18, 2019 Category: Consumer Health News Source Type: news

Patients' own cells could be the key to treating Crohn's disease(NIHR Biomedical Research Centre at Guy  s and St Thomas  and King  s College London) A new technique using patients' own modified cells to treat Crohn's disease has been proven to be effective in experiments using human cells, with a clinical trial of the treatment expected to start in the next six months. (Source: EurekAlert! - Medicine and Health)Source: EurekAlert! - Medicine and Health - February 15, 2019 Category: International Medicine & Public Health Source Type: news

A reflective group activity supports healthcare staff in EnglandRegular participation in structured organisation-wide forums, known as Schwartz Center Rounds ® , helps support healthcare staff. The forums are linked with increased empathy and compassion for colleagues and patients, and they facilitate practice change. Levels of poor psychological well-being decrease in forum attendees compared with non-attendees.
This NIHR-funded evaluation is the first mixed-methods, large-scale evaluation of the forums in England. They are now more widely adopted in the health service. The evaluation identifies learning and practical tips on running these forums well which could be useful for o...Source: Current Awareness Service for Health (CASH) - February 11, 2019 Category: Consumer Health News Source Type: news

Lifestyle changes may be more important than drugs for mild hypertensionA large NIHR-funded UK study compared rates of mortality and risk of cardiovascular disease between patients who received antihypertensive treatment and those who did not. There was an increased risk of adverse effects, like low blood pressure. It found no evidence to support starting drug treatment for adults of low-cardiovascular risk with mild hypertension. (Source: Current Awareness Service for Health (CASH))Source: Current Awareness Service for Health (CASH) - February 11, 2019 Category: Consumer Health News Source Type: news

E-cigs most effective in helping smokers quit, study saysA British study published in the New England Journal of Medicine found that e-cigarettes were almost twice as effective at helping people quit smoking as nicotine-replacement products like patches and gum.
The study, conducted by Queen Mary University in London and funded by Britain’s National Institute for Health Research and Cancer Research, found that when combined with one-on-one behavior therapy, using e-cigarettes was an effective path to smoking cessation.
A total of 886 participants… (Source: bizjournals.com Health Care News Headlines)Source: bizjournals.com Health Care News Headlines - January 31, 2019 Category: Health Management Authors: Anne Stych Source Type: news

E-cigs most effective in helping smokers quit, study saysA British study published in the New England Journal of Medicine found that e-cigarettes were almost twice as effective at helping people quit smoking as nicotine-replacement products like patches and gum.
The study, conducted by Queen Mary University in London and funded by Britain’s National Institute for Health Research and Cancer Research, found that when combined with one-on-one behavior therapy, using e-cigarettes was an effective path to smoking cessation.
A total of 886 participants… (Source: bizjournals.com Health Care:Biotechnology headlines)Source: bizjournals.com Health Care:Biotechnology headlines - January 31, 2019 Category: Biotechnology Authors: Anne Stych Source Type: news

New Cochrane review assesses the benefits and harms of exercise for preventing falls in older people living in the communityNew evidence published in the Cochrane Library today provides strong evidence that falls in people over sixty-years old can be prevented by exercise programmes.Falls are a leading cause of accidental or unintentional injury deaths worldwide. Older adults suffer the greatest number of fatal falls and over 37 million falls are severe enough to require medical attention each year.A new Cochrane Review produced by a team comprising researchers from the University of Sydney in Australia and University of Oxford, UK,summarizes the results from108 randomized controlled trials with 23,407 participants from across 25 countries. The...Source: Cochrane News and Events - January 30, 2019 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Radiotherapy benefits some men whose prostate cancer has spread to their bonesThis NIHR Signal adds further evidence that radiotherapy could benefit men with newly diagnosed prostate cancer with local metastases. The trial used CT and bone scans to define low and high metastatic burden. PET scans, which can detect smaller cancer deposits, are becoming widely available and may allocate people differently. However, the researchers did perform further analysis using different definitions of'low metastatic burden', with similar positive results. They are now planning to refine the definition to be more clinically useful.Nevertheless, radiotherapy can now be considered as a potential add-on treatment in ...Source: Current Awareness Service for Health (CASH) - January 30, 2019 Category: Consumer Health News Source Type: news

Researchers warn online GP consultations need careful implementationThe new NHS 10-year plan launched earlier this month [7 January] states all patients in England will have access to a " digital first primary care offer " , such as GP online consultations, by 2022/23. Online consultations have the potential to improve patient access and reduce face-to-face contacts, freeing up GP time. But research led by NIHR CLAHRC West and the Centre for Academic Primary Care at the University of Bristol found that unless these systems are carefully implemented, they won ’ t yield the benefits policymakers are hoping for. (Source: University of Bristol news)Source: University of Bristol news - January 22, 2019 Category: Universities & Medical Training Tags: Health, International, Research; Faculty of Health Sciences, Faculty of Health Sciences, Population Health Sciences; Press Release Source Type: news

Featured Review: Routine scale and polish for periodontal health in adultsExamining evidence for routine scale and polish treatment – an updated reviewThe Cochrane Review 'Routine scale and polish for periodontal health in adults' was carried out by authors working withCochrane Oral Health to assess the effects of routine scale and polish treatments for healthy adults and to establish whether different time intervals between treatments influence these effects. The review had aimed to compare the effectiveness of the treatment when given by a dentist compared to a dental therapist or hygienist, but there were no studies evaluating this comparison.This review updates the version publish...Source: Cochrane News and Events - January 15, 2019 Category: Information Technology Authors: Katie Abbotts Source Type: news

RWE: The Missing LinkThis article is from our latest'Trends in Real-World Evidence'magazine. Download for free.Data linkage challenges
Linking data is not an easy process; not only does it require the right technological tools and knowhow, it raises a range of concerns, from patient anonymity and data ownership, to how to transcend geographical barriers.Anonymizing data is a fundamental challenge, says Nigel Hughes, Scientific Director at Janssen Clinical Innovation – Patient Data for Research. “Data linkage requires, via an underlying consent model, linking different data together – with the patient being the common l...Source: EyeForPharma - January 7, 2019 Category: Pharmaceuticals Authors: Nicola Davies Source Type: news

Interview with Dr Ioannis Gallos lead author of the updated Uterotonic agents for preventing postpartum haemorrhage: a network meta ‐analysisThe aim of thisCochrane Review was to find out which drug is most effective in preventing excessive blood loss at childbirth and has the least side effects. The authors collected and analysed all the relevant studies to answer this question.The lead author of this review is Dr Ioannis Gallos. He is a Clinician Scientist in University of Birmingham and Honorary Consultant in Obstetrics& Gynaecology for Birmingham Women ’s Hospital. Ioannis obtained his Degree in Medicine and Surgery (DMS) cum laude from the University of Rome, Italy. He subsequently trained in Obstetrics& Gynaecology in the UK and sub-speciali...Source: Cochrane News and Events - December 20, 2018 Category: Information Technology Authors: Katie Abbotts Source Type: news

Ways of integrating care that better coordinate services may benefit patientsThis systematic review, part of the NIHR Signal series, looks at international literature to understand how new care models may affect patients, providers and systems. It includes a qualitative review of attitudes, barriers and enablers of integration and finds new integrated care models can increase patient satisfaction, perceived quality of care and improve access to services. It is less clear whether there may be effects on hospital admissions, appointments or healthcare costs. (Source: Current Awareness Service for Health (CASH))Source: Current Awareness Service for Health (CASH) - December 12, 2018 Category: Consumer Health News Source Type: news

Cochrane Library Special Collection: Diagnosing skin cancerThisSpecial Collection of Cochrane Systematic Reviews brings together a large body of research on the accuracy of tests used to diagnose skin cancer.The suite of eleven reviews was led by Dr Jac Dinnes at the University of Birmingham and supported by theCochrane Skin Group and a team of over 30 researchers and expert advisors, funded by the National Institute for Health Research (NIHR). The reviews summarise research evidence assessing the accuracy of different diagnostic tests to support clinical and policy related decision making in the diagnosis of all types of skin cancer. D...Source: Cochrane News and Events - December 5, 2018 Category: Information Technology Authors: Katie Abbotts Source Type: news

Are Smaller Hip Implants in Older Patients More Cost Effective?A study by researchers at the University of Bristol Medical School has shown that small-head cemented metal-on-plastic hip replacements less than 36 mm in diameter are the most cost-effective in patients older than 65.
The research was led by the Hip Implant Prosthesis Study (HIPS) team and found no evidence that uncemented or hybrid hip replacements are cost-effective options, while large-head implant sizes more than 36 mm in diameters are also not cost-effective.
To reach their conclusion the researchers used data from two large national cohorts, the National Joint Registry for England, Wales, and Northern Ireland, along...Source: MDDI - December 4, 2018 Category: Medical Devices Authors: Omar Ford Tags: Implants Orthopedics Source Type: news

Requests for emergency contraception could be an important sign of abuseWomen who experience domestic violence and abuse (DVA) are more than twice as likely to seek emergency contraception as other women, according to a study by National Institute for Health Research (NIHR)-funded researchers at the University of Bristol and Queen Mary University of London, suggesting that requests for emergency contraception could be an important sign of abuse. (Source: University of Bristol news)Source: University of Bristol news - December 4, 2018 Category: Universities & Medical Training Tags: Health, International, Research; Faculty of Health Sciences, Faculty of Health Sciences, Population Health Sciences; Press Release Source Type: news

Requests for emergency contraception could be an important sign of abuse(University of Bristol) Women who experience domestic violence and abuse (DVA) are more than twice as likely to seek emergency contraception as other women, according to a study by National Institute for Health Research-funded researchers at the University of Bristol and Queen Mary University of London, suggesting that requests for emergency contraception could be an important sign of abuse. (Source: EurekAlert! - Social and Behavioral Science)Source: EurekAlert! - Social and Behavioral Science - December 3, 2018 Category: International Medicine & Public Health Source Type: news

The University of Edinburgh - Centre for Medical Informatics: Research FellowLocation:
Edinburgh, UK
Job Type:
Full-Time
Employer:
The University of Edinburgh
Based in The University of Edinburgh's Usher Institute of Population Health Sciences and Informatics, this post offers an exciting opportunity to work with an established research group to contribute to an NIHR funded Programme to evaluate the Optimisation of ePrescribing systems in English hospitals. (Source: eHealth News EU)Source: eHealth News EU - November 30, 2018 Category: Information Technology Tags: Featured Jobs Source Type: news

Social care research gets up to £ 20 million boost from NIHRSocial care research in England is set to receive up to £ 20 million in new funding through the National Institute for Health Research, boosting research to improve adult social care across the country. (Source: University of Bristol news)Source: University of Bristol news - November 6, 2018 Category: Universities & Medical Training Tags: Announcements, Research; Faculty of Social Sciences and Law, Faculty of Social Sciences and Law, School for Policy Studies; Press Release Source Type: news

Cochrane prioritisation project informs NIHR tobacco research fundingIn 2016 the Cochrane Tobacco Addiction Group carried out a priority setting project (CTAG taps), funded by the NIHR School for Primary Care Research in the UK. Drawing on the opinions and experiences of members of the public, health professionals, healthcare commissioners, researchers, guideline developers and funders a clear message emerged- that there are still many unanswered research questions in the areas of tobacco use prevention, harm reduction and cessation. Now the NIHR have put out a large funding call, across a number of its funding streams, for research in these areas. The NIHR cite the findings of CTAG taps as...Source: Cochrane News and Events - November 1, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Data Flash: RIP PubMed HealthThis is not exactly a data post, but, the loss of a trusted source for clinical effectiveness research will have its effects on the dataverse. PubMed Health is being discontinued as of this coming Wednesday. As any of my colleagues can tell you, I’m taking the loss of PubMed Health hard– I loved showing it to people at various conferences, and using it myself– I found it a wonderful mid-point between MedlinePlus.gov and PubMed.gov, and it also had some great methodology resources and a glossary. All of its content will be findable in other ways though!
In thinking about how to proceed in...Source: Dragonfly - October 28, 2018 Category: Databases & Libraries Authors: Ann Glusker Tags: Data Science Public Health clinical effectiveness PubMed Health PubMed.gov search skills Source Type: news

An interview on consumer involvement in research with Simon Denegri, NIHRFor this year ’s Patients IncludedCochrane Colloquium, Richard Morley interviewed Simon Denegri, National Director for Patients, Carers and the Public, UK National Institute of Health Research. Simon talked about patient/consumer involvement in research, co-production, the role of researchers in meaningfully involving stakeholders, and what challenges he might set for Cochrane.Learn more about consumer involvement in CochraneTuesday, September 18, 2018 (Source: Cochrane News and Events)Source: Cochrane News and Events - September 18, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news