Some previous studies has demonstrated that Metformin can improve the weight gain which caused by antipsychotics. An our study, which will be published, also found that Metformin can improve the amenorrhea for patients with antipsychotics, approximately 60% patients recovery period. So the present study was designed to investigate the efficacy and safety of Metformin in preventing patients with Risperidone from weight gain and amenorrhea.

At screening, patients with abnormal results in physical examination, laboratory test, or electrocardiogram (ECG) were excluded.

Patients were also excluded if they met primary DSM-IV axis I psychiatric disorders other than schizophrenia, or ever used psychoactive substance.

Contacts and Locations

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To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01423487

Locations

China, Hunan

Mental Health Institute of The Second Xiangya Hospital

Changsha, Hunan, China, 410011

Sponsors and Collaborators

Central South University

Investigators

Study Chair:

Jing-Ping Zhao, Dr., Ph.D.

Mental Health Institute of The Second Xiangya Hospital, Central South University