I'm pretty sure it won't run at 60FPS on a 380, and probably not on a 380x. I tried to at 1080p with an NVidia GTX 960, which ran at about 40FPS on SEUS ultra motion blur and 16 render distance. The 380x doesn't really perform that much better than a 960 so I wouldn't say it could run at 60FPS, especially at 1440p. Without shaders it would be fine. My R9 270 (overclocked) can play at 1440p easily at a stable 90FPS(frame limited) on high settings (render distance 16 and fancy graphics etc). For the settings you have said you would need a R9 290/390 or a GTX 970.