This course is designed to have students experience the history of biology and cancer science as it evolved. Seminal papers in the last 100 years will be reviewed in a chronological fashion to have students appreciate seminal discoveries that advanced our fundamental understanding of human biology and the disease called Cancer. Through this journey, students will be able to experience how techniques and tools to study Biology evolved and how such knowledge was applied to understand and unravel new information about cancer. The course will highlight how such fundamental biology helped translate science and help generate drugs to combat cancer.