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Anemia Due to Enlarged Blood Cells in Dogs

Anemia, Megaloblastic (Anemia, Nuclear Maturation Defects) in Dogs

In this disease, red blood cells fail to divide and become abnormally large. These cells are also deficient in necessary DNA material. These giant cells with underdeveloped nuclei are called megaloblasts, or “big cells.” Red blood cells are mainly affected, but white blood cells and platelets can also go through changes.

Giant schnauzers seem to have an inherited tendency to have this kind of anemia. In dogs, it is generally mild, and left treated. The seriousness of the anemia can range from mild to severe. This disease is genetic in Toy Poodles, but it does not require treatment.

The condition or disease described in this medical article can affect both dogs and cats. If you would like to learn more about how this disease affects cats, please visit this page in the PetMD health library.