The Virgin, holding the Christ child, and St Catherine are sumptuously clothed in their heavenly space. In stark contrast St Dominic, from Spain, wears the black cloak and white tunic of his order while the donor, thought to be Domenico Balbi, is also sombrely dressed. A light-filled landscape indicates their earthly realm. The five figures dominate the foreground in this work, which Titian painted in his youth.