... The role of the different factors associated with fatty liver is still poorly defined. We evaluated the relationships between liver fat content (LF) and metabolic, inflammatory and nutritional factors in a homogeneous cohort of individuals at high cardio-metabolic risk.In 70 individuals with high waist circumference and at least one more criterion for metabolic syndrome enrolled in a nutritional i ...

... It has been previously demonstrated that miR-1934 was specially regulated by adiponectin, an anti-inflammatory adipokine, in adipose tissue (AT) in vivo. Herein we investigated the role of miR1934 in the regulation of inflammatory response. Compared with chow-diet fed mice, miR1934 expression was down-regulated in epididymal AT of high-fat diet-induced obese mice. miR1934 expression was down-regul ...

... Canned vegetables and fruit (CV+CF) are ubiquitous throughout the food supply. Yet information regarding their specific contribution to nutrient intake and health measures is lacking.The objective of this study was to examine the association of CV+CF with nutrient intake, diet quality, anthropometric indicators of overweight/obesity, and blood pressure in a nationally representative population.A s ...

... A diet rich in fruits and vegetables has been associated with several health benefits. However, the effects on body weight (BW) and metabolic markers are not fully known. The present study investigated the effects of increased intake of fruits and vegetables in overweight and obese men and women on dietary habits, anthropometry and metabolic control. In a 16-week controlled intervention, thirty-fo ...

... Objective : We aimed to determine the effects of the Dietary Approaches to Stop Hypertension (DASH) diet on the metabolic side effects of corticosteroid medication use. Design : A randomized clinical trial was undertaken in 60 patients on corticosteroid therapy for 10 weeks. Patients were randomly assigned to a DASH or control diet. Carbohydrate, protein, and fat in both groups were 50–60%, 15–20% ...

... The combined association of dietary fat, glycaemic index (GI) and fibre with type 2 diabetes has rarely been investigated. The objective was to examine the relationship between a high-fat, high-GI, low-fibre dietary pattern across adult life and type 2 diabetes risk using reduced rank regression. Data were from the MRC National Survey of Health and Development. Repeated measures of dietary intake ...

... The South Asian population suffers from a high prevalence of type 2 diabetes and cardiovascular disease (CVD). A unique obesity phenotype of elevated visceral adipose tissue (VAT) is associated with CVD risk among South Asians. Exercise-induced reduction in VAT and body fat is an effective mechanism to improve cardiometabolic risk factors but this has not been shown in South Asians. Whether exerci ...

... Objective: In China, high-fat diets and excessive energy intake have led to an increasing prevalence of obesity which was previously uncommon. The current study examined the effects of meal replacement (MR) on weight control in overweight or obese Chinese individuals with hyperlipidemia. Methods: Patients, 18–65 years, with body mass index 25–35 kg/m ² and triglycerides >1.7 and <5.4 mmol/L were e ...

... AIM: Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in women and confers a substantial health burden. It is important to explore modifiable extrinsic factors that contribute to disease risk. The aim of the present study was to compare the dietary intake, physical activity and physiological characteristics of women with PCOS with those of controls to identify lifestyle be ...

... PURPOSE: To prospectively examine the relation between adolescent dietary intake and cardiometabolic risk (CMR) clustering at the end of adolescence. METHODS: Data from the NHLBI Growth and Health Study on 1369 girls enrolled at ages 9–10 in 1987–1988 and followed for 10 years were used to estimate the relative risk of having multiple (≥2 or ≥3) risk factors in late adolescence associated with usu ...

... OBJECTIVES: To assess body composition, nutritional status and its differences between genders in a sample of Portuguese centenarians. DESIGN: Observational cross-sectional study. SETTING: Centenarians recruited in Portugal, able to give informed consent. PARTICIPANTS: A total of 252 subjects, with a median age of 100 years, mostly women (77.8%) who accepted to participate in the study, during the ...

... Evidence from epidemiologic studies has shown that total antioxidant capacity (TAC) in the diet might be inversely associated with stroke, heart failure, and inflammatory biomarkers. However, studies on the association of TAC from both diet and supplements with cardiovascular disease (CVD) risk factors in the U.S. population are lacking. This cross-sectional population-based study aimed to investi ...

... To assess the interaction of three single nucleotide polymorphisms in the C-reactive protein (CRP) gene and plasma fatty acid (FA) levels in modulating inflammatory profile.A total of 262 subjects, aged >19 y and <60 y, participated in a cross-sectional, population-based study performed in Brazil. Three single nucleotide polymorphisms (rs1205, rs1417938, and rs2808630) spanning the CRP gene were g ...

... A negative association between serum 25-hydroxyvitamn D (25[OH]D) concentrations and adiposity has been found in adults. We hypothesized that serum 25(OH)D concentrations of children would correlate positively with vitamin D intake and correlate negatively with adiposity measures. Using a nationally representative sample of children aged 6 to 18 years from the National Health and Nutrition Examina ...

... BACKGROUND: Few studies have linked major dietary nutrient patterns to chronic diseases. Despite the growing evidence of associations between dietary patterns and obesity, we are aware of no study that examined the association between patterns of nutrient intake and obesity. OBJECTIVE: To identify major nutrient patterns in Iranian adults and investigate their association with general and abdomina ...