BACKGROUND

A two-year postdoc position is available in the Regulatory Genomics group at the Center for Biological Sequence Analysis (CBS). The successful applicant will join a team of researchers working in the "Center for non-coding RNA in Technology and Health" (rth.dk) funded by the Danish Strategic Research Council.

Research within the regulatory genomics group at CBS is focused on the relationships between genotype, signaling, gene regulation and phenotype. The group consists of both biologists and computational researchers. Our research objectives relate to understanding the genetic basis for the differences in gene regulation and subsequent response to changing environmental conditions in different strains, cell lines or individual organisms. Data analysis and integration across diverse high-throughput data sources (e.g. genotypes, gene expression, protein expression, post-translational modification) is of a high importance. In addition, development of new computational and statistical methods for mining and exploiting systematic data resources are of interest.

The Center for Biological Sequence Analysis is focused on research in bioinformatics and systems biology and employs a staff of >100 with a highly multi-disciplinary background (molecular biologists, biochemists, medical doctors, physicists, computer scientists, and technical staff). The center represents one of the largest academic bioinformatics and systems biology groups in Europe.

Further information may be obtained from Associate Professor Chris Workman, workman[at]cbs.dtu.dk

You can read more about CBS at www.cbs.dtu.dk and the Center for non-coding RNA in Technology and Health at rth.dk.

RESPONSIBILITIES

The project will relate to developing models of RNA-protein interactions. Currently available experimental data on protein-RNA complexes, computational machine-learning methods, and experimental techniques for in vivo analysis of protein-RNA interactions, have enabled the investigation of protein-RNA interactions, their specificity and affinity. Aims of the project relate to understanding the function of different RNA-binding proteins (RBPs) and their target RNAs in post-transcriptional gene regulation.

REQUIREMENTS

Candidates should have a PhD degree or equivalent. The candidate should have a background in molecular biology, biotechnology, bioinformatics, computer science or similar subjects and an interest in working in a highly interdisciplinary and international setting. Interest in both the biological and computational aspects of modeling is essential. Experience with analysis of high-throughput data sets is highly desirable. Skills in managing or developing bioinformatics infrastructure are also desirable.

COMPENSATION

The appointment will be based on the collective agreement with the Confederation of Professional Associations. The allowance will be agreed with the relevant union.

HOW TO APPLY

To apply, please visit www.career.dtu.dk - open the link "apply online" and fill in the application form and attach a concise motivated application, CV including list of publications and diploma. The material that should be given consideration in the assessment must be attached. Applications should be submitted in English.