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Combination Prevention

Expanded high-impact prevention is needed to bring the epidemic to a conclusive end.

Combination or high-impact prevention is a set of strategically-selected interventions that matches the needs of a given country or community--and is delivered at the scale needed to make an impact. It means doing less of something and far more of others. It means making tough decisions and measuring impact. Above all, it means moving with clarity and speed.

There are emerging global definitions of what combination prevention is, and evolving models of what it can achieve. AVAC works with advocates to define what combination prevention means in a given context, track country and donor alignment with a combination prevention strategy and ensure that there is an implementation science agenda to fill in gaps in knowledge. To learn more about combination prevention in general and our work in particular visit the links below:

The majority of cisgender MSM and TGW who exchange sex and participate in this study are interested in PrEP, report taking sufficient PrEP, and stay on PrEP, though additional efforts are needed to address community misinformation and stigma. This novel multilevel, open-label study design and person-time approach will allow evaluation of the effectiveness and cost-effectiveness of combination prevention intervention in the contexts of both organized sex work and exchanged sex.

At the threshold of 2020, it’s clear that global goals for HIV prevention will miss the mark by a long shot. Though important progress has been made, the crisis UNAIDS called out in 2016 persists today with new infections around 1.7 million annually, a far cry from the 2020 target of fewer than 500,000. So, we asked ourselves, Now What?, and answered with cross-cutting analysis and an advocacy agenda to match.

As part of the HIV Prevention Coalition’s 2020 Roadmap, each of the 25 countries with highest number of new diagnoses receives a scorecard. The scorecards track progress in prevention efforts in five priority areas: adolescent girls and young women, key populations, condoms, voluntary medical male circumcision (VMMC) and pre-exposure prophylaxis (PrEP).

On the Blog

AVAC released Now What?, our 2019 annual report on the state of the HIV prevention field. Each year, the AVAC Report frames the most pressing advocacy issues facing the HIV response. At the threshold of 2020, it’s clear that global goals for HIV prevention will miss the mark by a long shot.