Comment by Carkasjak

For fast melee attackers this is by far the strongest Enhancement and will significantly ease your daily grind in Dread Wastes.

Comment by Nucleic

tooltip seems to be bugged or the skill doesn't hit for what it's supposed to either way,

says it will hit for 1,000,000+

only hits for me for 170k-180k

Comment by Noxyuz

Insanely good as a combat rogue. Blade flurry can trigger the serum on the secondary target too, making it possible to pull loads of mobs, use killing spree, and blow them all up in a matter of seconds. If used in combination with Battle Hymn, it pretty much makes you play in God Mode as you'll be getting constant heals while doing insane damage.

Comment by DiViDE

When this explodes it will clear stacks from other mobs hit by the explosion.

Comment by Alfa

For hunters, spec into Barrage and you will get two full serum shots before its done casting.

Comment by Draconax

Insanely effective for doing dailies as a Mistweaver. 1 sec GCD combined with jab spam allows you to stack this incredibly fast. Even single quest mobs with 1mil+ hp die in under 20 seconds with this abilities, as you stack it in 4-5 seconds. This is by far the best enhancement you can take while questing as a mistweaver (or likely a monk in general).

Comment by dpatchen1229

Throw's 0.5 second cast and no GCD makes this buff a deadly opener for warriors. You can easily get 8 stacks on a mob before it gets to you, or on a player before they know what's hitting them.

Comment by Chumbado

Guardian Druid's Growl confirmed to apply 1 stack of poison, just as faerie fire, very easy to reach 8 stacks with the bear.

Comment by salvo711

It seems that they nerfed this ability quite hard with patch 5.1 (quite stealthily might I add). As an unholy death knight the injections used to skyrocket to 8 in a matter of a few seconds... right now I'm barely ever seeing the stacks reach 8 at all before my targets die. Can anyone confirm/deny whether they're experiencing the same issue?

Edit: Seems like our only recourse is going back to Kil'ruk for Angel of Death, then.

Comment by elprimo84

Seems to have been nerfed with 5.1 it used to proc all the time but now most mobs die without it getting to full stacks.

Comment by xerics

Looks like they just stealth nerfed this enhancement. It now has an internal cooldown that is the same as a global cooldown.

Comment by Lancun

Amazingly has gone from one of the best Enhancements to one of the worst. As others below have stated, the Global Cooldown these procs have now makes sure that most mobs die before you even get a full stack, even when you pull large groups and happen to be cleaving. This means the buff's only useful for Rare Spawns, and even then, Silent Lucidity, Angel of Death, or Children of the Grave (if there are adds around) are comparable to this in terms of damage benefit.

The reasoning for this escapes me. While it was certainly a powerful buff before, turning it into something WORTHLESS for standard mobs and only marginally useful for Champions seems a bit much.

Comment by Anedill

I get the feeling that since patch 5.1, this buff has been shrunk in power. Building up the stacks is slower and they do nowhere near as much damage when exploding than before 5.1. :(

Comment by Archaelias

Yep, the speed of application totally got nerfed. Maybe cuz jerks like me used this for hunting the rares in the area and obliterating them a little too easily.

Comment by jmok

I do believe this was nerfed a bit after the 5.1 patch. Not that I'm complaining

Comment by Waterhouse

Was this nerfed in 5.1? Seems to stack a lot slower for my Enh Shaman...

Comment by urakantu

seems to be nerfed after 5.1i dont have a certain information but it seems so to me.can anyone confirm ?

Comment by Titanius05

Today while working on my rogue, I used distract...and one charge went to the mob I was distracting...broke stealth, and got my face bashed in.Sap also applies the debuff. Blind does not.

Without sap and distract, this is just unbelievable bad for rogues.

edit: added about sap/blind

Comment by Seniorold

On my Paladin i used to get procs on this using AoE abilities like "Mass Exorcism" and "Hammer of the Righteous" when pulling big packs of mobs, which meant all mobs in the pack would get the debuff.

What would end up happening was that the first mob i targeted would usually die to melee and the abilities i used, but then i would switch to the second target which had like 3-5 stacks and continue to AoE, at this time somewhere in the pack of mobs the "Unstable Serum" would go off and stun all enemies.

Tbh i saw nothing overpowered with this since when "Unstable Serum" went off it would remove the debuff from all the other mobs in the pack and stun them instead of keeping the stacks of the debuff which would basically kill the whole pack in rapid succession.

Now they Nerfed it so it does NOT proc on all targets in a pack of mobs when using AoE abilities, and what will happen then is what i explained above, i would kill the mob before it goes off, and there is no longer mobs to switch too which got like 3-5 stacks of the debuff to continue building on until "Unstable Serum" goes off.

(This is my first comment, so it's not very well made compared to other comments I've seen. I just want to explain what I've noticed)