2016 NFL Week 3 Opening Line Report

Week 2 of the NFL season is in the books; however, it ended with several key players suffering significant injuries. Jimmy Garoppolo (shoulder), Adrian Peterson (knee), and Jay Cutler (hand) all left their games with injuries that will likely sideline them for Week 3.

Overall, the biggest changes are due to injuries at the quarterback position. The New England Patriots and Cleveland Browns will enter Week 3 with rookies under center. Although things could change before kick-off, it appears that Jacoby Brissett of NC State will start for the Patriots (+1) on Thursday and Cody Kessler of USC will start for the Browns (+10) on Sunday. Unlike Brissett, who filled in when Garoppolo left the game, Kessler has yet to throw a regular-season pass. The Pats are rarely underdogs, but it is profitable to back Bill Belichick’s squad when they are getting points (23-9 ATS, +13.45 units per BetLabsSports.com).

Another huge discrepancy is in the San Francisco-Seattle game. The Seahawks were -14 back in April, but have since dropped to -9 at the time of publication. While the defense has been one of the league’s best, Seattle’s offense has been shaky, putting up 15 points in Weeks 1 and 2 combined. Despite their struggles on offense, oddsmakers still believe in the Seahawks and expect that the 49ers will suffer another lopsided defeat.

These numbers are subject to change before kickoff, so bettors should be sure to visit our free NFL odds page for the latest lines, injuries, public betting trends and more.

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