INDICATION

DOSING INFORMATION

Before starting on ARICEPT 23 mg/day, patients should be on ARICEPT 10 mg/day for at least 3 months. The starting dose of ARICEPT is 5
mg/day and can be increased to 10 mg/day after 4–6 weeks. Please take ARICEPT as prescribed by the doctor.

IMPORTANT SAFETY INFORMATION

ARICEPT is not for everyone, including people who are allergic to any ingredients in ARICEPT or to medicines that contain piperidines.

Tell the doctor if your loved one takes nonprescription or prescription medicines, including those used to treat Alzheimer's or Parkinson's
disease; anticholinergic medicines, such as allergy or cold medicine; medicines to treat bladder or bowel spasms; or certain asthma medicines.

ARICEPT may cause slow heartbeat and fainting. This happens more often in people with heart problems. Call the doctor right away if the patient
faints while taking ARICEPT. People may also have seizures while taking ARICEPT. They may also have difficulty passing urine. Lung problems, including asthma,
may worsen with the use of ARICEPT. Tell the doctor that the patient takes ARICEPT before they have any procedure that may require anesthesia, including dental
and medical procedures or surgery.

People at risk for stomach ulcers or who take certain other medicines, such as aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs), should
tell their doctor because serious stomach problems, such as bleeding, may get worse.

In a study, more side effects were seen with ARICEPT 23 mg than with ARICEPT 10 mg. Many more people taking ARICEPT 23 mg experienced nausea and
vomiting than those taking ARICEPT 10 mg. These side effects may get better after the patient takes ARICEPT for a while. Other side effects that were seen more
often with ARICEPT 23 mg were stomach ulcers, gastrointestinal bleeding, and weight loss. People of lower weight (less than 121 lbs) may have increased nausea,
vomiting, and weight loss when taking ARICEPT 23 mg.

Other side effects of ARICEPT may include diarrhea, difficulty sleeping, vomiting, or muscle cramps. Some people may feel tired or may have loss
of appetite.