Abstract:To optimize the extraction process of flavones from black bean by microwave and studied its antioxidant activity, on the basis of single factor tests, selected the ratio of ethanol to material, volume fraction of ethanol and the microwave power as the independent variables and the yield of flavones as response value, the method of response surface analysis with 3 factors and 3 levels was adopted. A quadratic regression equation of prediction model was acquired. The results showed that the optimal conditions for extraction was as follows: Power 600 W, ratio of ethanol to material 40∶1 and volume fraction of ethanol 60%. Under those conditions, the yield of the flavones was up to 22.1 mg·g-1. The flavonoids in black bean, which were a kind of good source for natural antioxidants, showed relatively strong antioxidant activities on oil.