ADA051728

Title:

Insulin-like Effects of Taurine,

Descriptive Note:

Corporate Author:

ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FREDERICK MD

Personal Author(s):

Report Date:

1978-03-17

Pagination or Media Count:

12.0

Abstract:

A one-time injection of taurine in a dose of 200 mgkg will increase insulin-like activity in rat plasma, doubles the glycogen content of the liver and decreases glycemia. In in vitro experiments taurine increases glucose absorption by isolated diaphragms and raises insulin activity. On the basis of increased adenylacyclase activity in incubated diaphragms upon introduction of taurine and insulin-like action of 3, 5, -AMF and theophylline the conclusion was made that the insulin-like effect of taurine is mediated through cyclic AMF. Author