PLOS ONE Associate Editor Carla Pegoraro highlights some of the latest research on the development and uses of chemical probes, including in vivo and in vitro imaging, drug discovery, protein functions and cellular processes.

PLOS NTDs Editor-in-Chief Serap Aksoy has assembled a collection of previously-published Yellow Fever research articles that are of interest considering the 2015-2016 outbreaks of Yellow Fever in Africa and Brazil.

This collection, as selected by PLOS ONE Associate Editor, Adya Misra, highlights publications that represent recent developments in molecular biology with a special focus on genome editing and high throughput sequencing.

Research exploring how cells work helps us understand the proper functioning of the body, as well as understand and treat disease. Senior Editor Meghan Byrne has selects recent papers highlighting the critical research PLOS journals publish in this area.

Open Highlights use recent PLOS Biology research articles as keystones around which to nucleate a short synthesis of up to ten related research articles from other PLOS journals and from the wider Open Access corpus.

This collection investigates a series of questions about the welfare of North American zoo elephants using epidemiological methods. The studies provide objective information about how the elephants are faring, identify the most salient connections between their daily lives and a range of behavioral and physical welfare outcomes, and support advances in evidence-based zoological management.

Each year, norovirus causes over 200,000 deaths and a global economic burden of more than $60 billion. In this PLOS Collection global norovirus experts fill critical knowledge gaps and provide key information to further development of a much-needed vaccine.

PLOS and iGEM share a belief that science is best advanced through openness. Submissions to the PLOS iGEM Collection will be posted for open review on the PLOS Collections blog, where members of the PLOS and iGEM communities will review them openly.

Understanding Images is a collection of posts and articles from a PLOS Genetics blog series. The aim of the series is to showcase the research that created or inspired the journal's cover image, and explain how the image helps us to understand the research question addressed in the manuscript.

To celebrate the 10th anniversary of the launch of PLOS Pathogens, over 60 Section Editors, all experts on studies of viruses, bacteria, prions, fungi, oomycetes and parasites of animals and plants, were invited to select articles that they believed represented the very best exemplars from their respective fields.

2015 marks the tenth anniversary of PLOS Genetics and brings with it a host of celebrations to mark this momentous occasion. This collection exhibits some of the best research PLOS Genetics has had the privilege to publish over the past decade.

PLOS Pathogens presents an Open Access compendium of "lessons-that-last." This living collection of short, educational, and highly useful articles addresses topics of relevance and importance within the wide-ranging field of pathogens research, with insights tailored to graduate students and post-docs.

This Collection describes multiple parasite and host processes engaged in infection in blood, the blocking of which could stop human illness. Control and eradication of malaria will also require the development of drugs against stages responsible for mosquito transmission and those that remain latent in the liver.

This new PLOS Collection discusses major efforts by evolutionary biologists and paleontologists to understand sauropods as living animals and to explain their evolutionary success and uniquely gigantic body size. The articles address these questions from the widest selection of disciplinary viewpoints, including those of ecology, engineering, functional morphology, animal nutrition and palaeontology.

Broad categories focus on DNA synthesis and assembly techniques, the development of libraries for biological parts, the use of synthetic biology in protein engineering applications, work focussing on synthetic life and multicellular systems, gene editing, and the engineering of gene regulatory networks and metabolic pathways.

This collection represents a first step in gathering under easily identifiable rubrics some of the most recent neuroscience research published across the PLOS journals. The Collection has been organized into broad categories to provide more structured and efficient access to papers of interest in the PLOS corpus.

This collection reports the results of the efforts of investigators, in providing important, practical details on studying immune responses in the genital and rectal mucosa, which will help guide future studies of HIV prevention.

The technical advances highlighted in this collection exemplify how basic research discoveries are being translated into methods to develop and improve, both agriculturally and environmentally, important crop traits.

This collection collates some of the best and most recent immunobiology articles published at PLOS, featuring papers that examine cellular and molecular immunology, evolutionary immunology, animal models of the human immune system and ontogeny of the immune system.

This series aims to investigate whether, and under what conditions, it is possible to engage the public in scientific issues in meaningful ways in decision-making about the innovation pathways of biosciences.

This collection contains manuscripts that describe functional findings on various tsetse biology. In addition two manuscripts reflect on the unique historical aspects of sleeping sickness epidemics that have plagued sub-Sahara in the 20th century.

PLOS Neglected Tropical Diseases has dedicated a special collection to VL-HIV co-infection including basic and molecular work, immunological and diagnostic studies, clinical studies, and public health aspects.

In response to the 2014 Ebola outbreak in West Africa, PLOS editors curated content from across the seven journals, PLOS Currents and the PLOS Blogs Network into a rapidly evolving collection of research.

The Pacific Ocean Shelf Tracking (POST) Program seeks to advance understanding of the movement and behavior of marine animals through the use of a large-scale acoustic telemetry and data management system.

The Rosetta framework for macromolecular modeling, prediction and design is a widely used code with a large, dynamic developer community. This special collection presents recent developments from the Rosetta community, drawn from the groups participating in RosettaCon 2012.

The Rosetta framework for macromolecular modeling, prediction and design is a widely used code with a large, dynamic developer community. This special collection presents recent developments from the Rosetta community, drawn from the groups participating in RosettaCon 2010.

The Italian Space Agency contracted Thales Alenia Space Italia to build a spaceflight payload (Mice Drawer System (MDS)) for mice research on the International Space Station (ISS), including wild type and transgenic strains. These studies examined changes that occurred in the animals.

This collection of articles represents the output of a group of international research institutions (informally referred to as EUMOOD) who collaborated around the causal link between stress exposure and depression vulnerability.

The Prokaryotic Genome Collection is an attempt to present and highlight a number of important articles that describe whole genome sequence and/or comparative genomics of important prokaryotic organisms.

This collection of articles represents some of the research highlights from the SGC, an international public-private partnership that determines three dimensional structures of medically important proteins from both human and human parasites and places this information into the public domain, free from restrictions on use.

In a joint venture between PLOS Computational Biology, PLOS ONE and the conference program committee, this collection draws together papers from the 6th Annual RECOMB Satellite on Regulatory Genomics and the 5th Annual RECOMB Satellite onSystems Biology, held jointly at MIT, December 2-6, 2009.

Funded by the National Institutes of Health Common Fund, the Human Microbiome Project (HMP) was established to provide a comprehensive baseline of the microbial diversity at 18 different human body sites. The Human Microbiome Project Collection encompasses publications from the project.

This Collection contains papers representing the output of the best performing methods in the DREAM challenges, which themselves were discussed and presented at the DREAM (Dialogue for Reverse Engineering Assessment and Methods) conferences, which have been running annually since 2007.

These articles describe the technical and applied aspects of GM insects. We have also included articles that are not strictly GM, but aim to modify the disease transmission traits of insects through the use of symbiotic microbes.

In celebration of the Tenth Anniversary of PLOS Biology, this collection showcases ten specially selected PLOS Biology research articles, drawn from a decade of publishing excellent science. The articles, which were chosen by PLOS Biology's Editors and Editorial Board, are representative of the high quality research published in the journal over the last decade.

This collection features articles describing findings that redefine the landscape of the mammalian transcriptome by introducing an extensive collection of novel cDNAs and millions of sequenced tags corresponding to 5'- and 3'-ends of mRNAs.

The J. Craig Venter Institute's Global Ocean Sampling Expedition revealed an enormous amount of unexplored diversity in the world's oceans. This collection includes commentary and analysis highlighting the achievements and challenges of this work.

This Collection has been created by the editors of the World Register of Marine Species, an open-access online database which holds information on all marine species, and some of their freshwater and terrestrial relatives.

Through a global network of researchers in more than 80 nations, the Census of Marine Life (2000-2010) has engaged in a coordinated scientific program to assess and explain the diversity, distribution, and abundance of life in the oceans.

This collection of papers presents research in the field of Marine Barcoding under the auspices of MarBOL: a joint effort of the Consortium for the Barcode of Life (CBOL) and the Census of Marine Life to enhance our capacity to identify marine life by utilizing DNA barcoding.

This collection of papers highlights research performed under the auspices of the Tagging of Pacific Predators (TOPP) program, a component of the Census of Marine Life (CoML). TOPP is a multi-institutional, multi-year large-scale biologging program that has deployed nearly 4300 tags on 23 marine species throughout the Pacific Ocean.

This collection of brief provocative discussion papers, initiated and edited by Simon Levin, aims to highlight fundamental questions in biology that cut across and help unify different biological disciplines.

PLOS Pathogens and PLOS Neglected Tropical Diseases sent a collection of primary research articles on topics spanning these sister journals, including: proteomics, kinetoplastids, insect vectors, genomics, and transcriptomics within the context of the NTDs.