The Children’s Brain Tumor Tissue Consortium (CBTTC) is a collaborative, multi-institutional research program dedicated to the study and treatment of childhood brain tumors. The CBTTC supports the research of new prognostic biomarkers and therapies for children with pediatric brain tumors. The CBTTC consists of 16 primary member institutions and has enrolled more than 2,546 subjects and contains over 40,000 tubes of specimens, all highly annotated with longitudinal clinical data, genomic data, imaging and histology data and available for request by researchers across the world.

The CBTTC’s Pediatric Atlas is one of the world’s largest pediatric brain tumor data sets and was released without embargo on September 10, 2018.

To search the PBTA files and associated meta data please visit the Kids First DRC portal. There you will be able to identify genomic and associated files and seamlessly integrate them into a Cavatica workspace for research on the raw genomic data. The PBTA summary data is available on PedscBioPortal for analytic visualization.

Researchers can request access to the raw genomic data by completing and submitted the CBTTC Data Access Request form.

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The Center for Data Driven Discovery of Biomedicine at Children's Hospital of Philadelphia is a transformative healthcare discovery ecosystem which provides innovative care for all children through collaborative, data-driven science.