Douglas County, Kan., funds by Health and Human Services, Department of

Note: For some programs where states do not report where money will be distributed across the state, we do not have the allocation for individual counties. Those programs include: Medicaid, unemployment benefits and food stamps. Those amounts are included in the totals for where the state agency receiving that money is located.

Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.

Recipient

Amount

Description

Federal Dept./Agency

Date

UNIVERSITY OF KANSAS CENTER FOR RESEARCH, INC.

$4,657,861

Trans-NIH Recovery Act Research Support The University of Kansas Lawrence campus requests funding to renovate and expand 3646 gross square feet (gsf) in Nichols Hall designated as the Bioinformatics Computing Facility core (BCF). The renovated space will support computationally intensive multid

Trans-NIH Recovery Act Research Support One of the major unsolved problems in drug delivery is how to transport poorly permeable molecules across membrane barriers and release them in specific cells or tissues. The way that Nature solves this problem is through membrane trafficking; cell imperm

Trans-NIH Recovery Act Research Support Inflammatory bowel disease (IBD) is a chronic inflammation of the GI tract that includes Crohn's disease and ulcerative colitis. The major enzymes involved in mediating the inflammatory response in IBD are cyclooxygenase (COX), lipoxygenase (LOX) and nitr

Trans-NIH Recovery Act Research Support We propose to investigate the role of epileptic seizures in oxidative stress. There is a wealth of research that demonstrates epileptic seizures lead to the formation of reactive oxygen species (ROS), which cause oxidative damage to DNA, lipids, and prot

Trans-NIH Recovery Act Research Support Complex diseases are controlled by a large number of potentially interacting genetic and environmental factors. Each year millions of Americans are diagnosed with complex diseases such as diabetes, heart disease, Alzheimer's, and various forms of cancer.

Trans-NIH Recovery Act Research Support The 90 kDa heat shock proteins are proving to be extraordinary cancer chemotherapeutic targets as evidenced by the fact that more than 20 clinical trials are currently in progress. Unfortunately, all of these trials are based upon N-terminal inhibitors,

Trans-NIH Recovery Act Research Support One of the major unsolved problems in drug delivery is how to transport poorly permeable molecules across membrane barriers. The way that Nature solves this problem is through membrane trafficking; cell impermeable ligands such as the iron-carrying transf

Trans-NIH Recovery Act Research Support Organic synthesis provides access to novel chemical entities essential for human health research as biological probes, libraries for high-throughput screening, and even as drug candidates. However, traditional chemical methodology development and reaction

Trans-NIH Recovery Act Research Support Considerable advances have been made in the study of opioid receptor structure and function, and in recent years evidence has accumulated that opioid receptors can interact with one another. Early studies demonstrated that antagonism of delta opioid recep

Trans-NIH Recovery Act Research Support The long-term objective of this application is to regenerate a patient-specific temporomandibular joint (TMJ) condyle using a process free of solvents, particulates and polymerization initiators. In a broader sense, this technology can be readily applied

Trans-NIH Recovery Act Research Support Radioresistance markedly impairs the efficacy of radiotherapy and involves cell signal transduction pathways that prevent radiation-induced cell death. Proteins in the Bcl-2 family are central and dual regulators of apoptosis and autophagy, and members th

Trans-NIH Recovery Act Research Support Tumor-initiating cells, or cancer stem cells (CSC), are a small subpopulation of cells capable of self-renewal and differentiation, which are highly resistant to chemo/radiation therapy and may be responsible for tumor recurrence and metastasis. The tumo

Trans-NIH Recovery Act Research Support Tumor-initiating cells, or cancer stem cells (CSC), are a small subpopulation of cells capable of self-renewal and differentiation, which are highly resistant to chemo/radiation therapy and may be responsible for tumor recurrence and metastasis. The tumo

Trans-NIH Recovery Act Research Support Human cytochrome P450 (CYPs) are essential enzymes involved in clearing drugs and foreign chemicals from the body. The last decade of cytochrome P450 research suggests that many P450 proteins undergo induced fit in response to ligand binding and that liga

Trans-NIH Recovery Act Research Support This proposal requests support to continue development of a Center of Biomedical Research Excellence in Protein Structure and Function (COBRE-PSF) at the University of Kansas. Our Center was established in October 2002, and includes participants from thre

Trans-NIH Recovery Act Research Support We seek continuation of the University of Kansas (KU) IMSD program, a program whose underrepresented scholars are enrolling in graduate programs in the sciences at more than twice the national average, and that has succeeded in bringing five American Indi

Trans-NIH Recovery Act Research Support This program of investigation focuses on the genetics of Specific Language Impairment. We investigate longitudinal behavioral language phenotypes within a multi-gene developmental model involving a complex interaction of genetics, developmental brain chan

ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for the Child Care and Development Fund (CCDF); Description: The CCDF ARRA funds will be used to provide child care financial assistance to low-income working families and fund activities to improve the quality of child ca

Trans-NIH Recovery Act Research Support Most children transition from presymbolic (e.g., gestures and vocalizations) to symbolic (e.g., words) communication during the first year of life. This transition enables children to communicate more efficiently and leads to further developments in langu

Trans-NIH Recovery Act Research Support The protein-protein docking problem is one of the focal points of activity in computational structural biology. The 3D structure of a protein-protein complex, generally, is more difficult to determine experimentally than the structure of an individual pr

Trans-NIH Recovery Act Research Support A major problem with drugs of abuse is the return to drug use after a period of abstinence (relapse). A contributing factor to relapse is the withdrawal-induced anxiety and depression, which stimulates re-administration as a form of self-medication. Super

ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for the Child Care and Development Fund (CCDF); Description: The CCDF ARRA funds will be used to provide child care financial assistance to low-income working families and fund activities to improve the quality of child ca

Trans-NIH Recovery Act Research Support Chlamydiae infections have an immense impact of public health causing sterility, blindness, pneumonia, and correlated with formation of atherosclerotic lesions and heart disease. These obligate intracellular bacteria are perpetuated through a developmenta

Trans-NIH Recovery Act Research Support Chlamydia are human pathogens that cause sterility, blindness, pneumonia, and are strongly correlated with the number one cause of death in humans, heart disease. Chlamydia are obligate intracellular bacteria that are perpetuated through a defining bi-pha

Trans-NIH Recovery Act Research Support Out of 290 million dental restorations placed/year in the U.S., 200 million are replacements for failed restorations. This emphasis on replacement therapy is expected to grow as the public's concern regarding mercury and dental amalgam forces dentists to

Trans-NIH Recovery Act Research Support Dengue viruses (DENV), members of mosquito-borne flaviruses of Flaviviridae family, are included in the NIAID Category A Priority Pathogen as they cause frequent epidemics and serious illness with considerable morbidity and mortality. Two-thirds of human

ARRA ? Equipment to Enhance Training for Health Professionals The University of Kansas, Clinical Psychology Program Lawrence Kansas (KU-Lawrence) and the University of Kansas School of Medicine Center Kansas City (KUMC) seek funding to buy equipment to support the development of a TeleBehavioral SlSleep Medicine (T-... Show more

Trans-NIH Recovery Act Research Support Herpes simplex virus (HSV) is a common and significant pathogen which causes a variety of disease processes in humans, ranging from cold and genital sores to Herpes simplex virus (HSV) is a common and significant pathogen which causes a variety of disease

Trans-NIH Recovery Act Research Support The Kansas IDeA Network of Biomedical Research Excellence (K-INBRE, first known as the K-BRIN) was established in 2001 as a network of 9 Kansas institutions of higher learning. Kansas falls into the bottom half of states receiving research funding from th

Trans-NIH Recovery Act Research Support The Kansas IDeA Network of Biomedical Research Excellence (K-INBRE, first known as the K-BRIN) was established in 2001 as a network of 9 Kansas institutions of higher learning. Kansas falls into the bottom half of states receiving research funding from th

Trans-NIH Recovery Act Research Support The 500 Nations Haskell / KU Bridge program supports students from Haskell Indian Nations University who seek to transfer to other institutions; it works collaboratively with other MORE programs (IMSD, RISE, PREP, and IRACDA) to move American Indians into

Trans-NIH Recovery Act Research Support Over the past six years, a partnership between Haskell Indian Nations University and the University of Kansas has been forged to achieve the goal of bringing more American Indians into the biomedical research community. With support from the NIGMS MORE pr

Trans-NIH Recovery Act Research Support Disordered and/or delayed communication and language development constitute a defining characteristic of mental retardation. The proposed research is guided by a conceptualization of communication and language development that stresses the central role of

Trans-NIH Recovery Act Research Support This application requests continued support for the doctoral training program in Dynamic Aspects of Chemical Biology in the Departments of Chemistry, Medicinal Chemistry, Molecular Biosciences, and Pharmaceutical Chemistry at the University of Kansas. Thi

Trans-NIH Recovery Act Research Support The pathogenesis of Gram-negative septic shock, a leading cause of mortality in critically ill patients, is a consequence of the overwhelming innate immune response to endotoxins, or lipopolysaccharides (LPS), present on the surface of Gram-negative bacte

Trans-NIH Recovery Act Research Support In terms of health, Wyandotte County ranks 105th out of the 105 counties in the state of Kansas. Wyandotte County is a G??majority minorityG?? county with high rates of poverty, unemployment, poor access to healthcare and excessive morbidity and mortality

Trans-NIH Recovery Act Research Support This proposal will use the interferon-gamma binding protein from ectromelia virus (IFN-gBPECTV) to design new cytokine antagonists and improved research reagents with broad applications to many disciplines. Preliminary structural studies on IFN-gBPECTV h

Trans-NIH Recovery Act Research Support The Kansas IDeA Network of Biomedical Research Excellence (K-INBRE, first known as the K-BRIN) was established in 2001 as a network of 9 Kansas institutions of higher learning. Kansas falls into the bottom half of states receiving research funding from th

Trans-NIH Recovery Act Research Support The Kansas IDeA Network of Biomedical Research Excellence (K-INBRE, first known as the K-BRIN) was established in 2001 as a network of 9 Kansas institutions of higher learning. Kansas falls into the bottom half of states receiving research funding from th

Trans-NIH Recovery Act Research Support The primary goal of this Program Project is to use a synergistic combination of genomics, molecular genetics and natural products chemistry to identify and purify potentially useful secondary metabolites of the filamentous fungus Aspergillus nidulans. The