Nose, Olfactory Epithelium - Metaplasia, Respiratory - Gallery

Nose, Olfactory epithelium - Metaplasia, Respiratory in a female B6C3F1/N mouse from a chronic study. There is replacement of olfactory epithelium by ciliated, respiratory epithelium.

Nose, Olfactory epithelium - Metaplasia, Respiratory in a treated male B6C3F1/N mouse (left) and normal olfactory epithelium from a control male B6C3F1/N mouse from a subchronic study (right). The olfactory epithelium of the treated mouse has been replaced by respiratory epithelium. Image provided courtesy of Dr. R. Miller.

Nose, Olfactory epithelium - Metaplasia, Respiratory in a male B6C3F1/N mouse from a chronic study. The olfactory mucosa has been completely replaced by respiratory epithelium, and there is concurrent atrophy of the olfactory nerves. Image provided courtesy of Dr. R. Miller.

Nose, Olfactory epithelium - Metaplasia, Respiratory in a control B6C3F1/N mouse from a chronic study. There is localized replacement of the olfactory mucosa by respiratory epithelial cells (arrow) and dilation of Bowman�s glands. Image provided courtesy of Dr. R. Miller.