Lead investigator Professor Craig Anderson of The George Institute for Global Health said: “Many stroke specialists believe that the way the body is positioned after stroke makes a difference to their patient’s recovery. But, there was really no conclusive evidence to back this up.

“We know the first 24 hours of care post-stroke is crucial to recovery, so it was vital to find out if sitting up or lying down flat could make any difference.

“What we found is that head position does not matter so much over and above good nursing care. It does not help with recovery, with mortality or how a patient feels. However, we also found there were no significant harms associated with either lying down flat or sitting up.”

The study is the largest ever randomised nursing care trial and took place at 114 hospitals in the UK, Australia, China, Taiwan, India, Sri Lanka, Chile, Brazil and Colombia.

Patients were either assigned to lie flat with their face upwards or with their head raised to at least 30 degrees during the first 24 hours after being admitted to the hospital for a stroke. They were then assessed 90 days later.

Professor Craig Anderson said the results were very reassuring to lower to middle income countries, where lying flat is more commonly practiced due to the lack of motorized beds.

“What we found is that patients found lying flat somewhat uncomfortable, but it certainly didn’t make their condition any worse. Our findings suggest a review of current clinical practice guidelines is warranted,” Professor Anderson added.

The majority of patients who took part in the study had mild to moderate severity strokes, with an average age of 68 years.