Analysis of Mycotoxins in Food Matrices using the Innovative Ultivo Triple Quad LC/MS

Mycotoxins are compounds produced by fungi which grow on various groups ranging from grains to fruits, vegetables, nuts and spices. Mycotoxins can be harmful to humans and livestock through consumption of contaminated crops; therefore, mycotoxin levels are monitored in foods to minimize the risk of ingestion. Regulatory agencies around the globe set Maximum Residue Limits (MRLs), which range from <10 to >500ppb to ensure harmful levels of mycotoxins do not enter the food supply. It is important to have the ability to detect and accurately quantify mycotoxin contents at low levels across various food matrices, as each matrix composition poses different challenges in detection.

In this study, we demonstrate the accurate and sensitive quantification of up to 12 regulated mycotoxin compounds in three commonly regulated foods using the novel Ultivo triple quad LC/MS.

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Sample preparation is a key step in the analysis processParameters for evaporation and their impact on analysis have been discussedImprovements in matching the sample to the evaporation device characteristics can help reduce variability and improve recoveryExamples for choosing a system based on sample volume, types of analytes, sample load, and initial investment considerations