Paper published in Nature Protocols

A team of LIMMS researchers has just reported in Nature Protocols the detailed methodology of a droplet-based microfluidic platform. This tool has enabled for the first time to map with high precision the dynamics of nonlinear biochemical circuits, such as a DNA bistable switch and a DNA predator prey oscillator. But focus of the platform extends beyond nonlinear chemistry and could find in principle be applied to any protocols that needs to be optimized. In order to enable non experts to implement the microfluidic platform, LIMMS researchers have now published a detailed paper covering all aspects of the platform, ranging from microfabrication and microfluidic operation to image acquisition and data processing.