Research using the adult mammalian model shows that regeneration in the limb is limited to the distal most portion of the terminal phalanx. Recent studies suggest that the cellular contributions made to the regenerating system are lineage...

In an attempt to understand the patterning regulation during limb development, three approaches have been taken in current studies. First, the relationship between cellular position and growth has been studied in cultures of dissociated fragments...

Synthesis and characterization of anisotropic micro- and nanoparticles, either in suspension or localized on a surface, are current areas of intense scientific interest because of their shape-tunable material properties with potential applications...

Patterning of the vertebrate limb appears to be mediated by position-specific cell-cell interactions. Evidence for these interactions stem from grafting experiments in which posterior (zone of polarizing activity or ZPA) tissue is placed into an...

It has been known for over three quarters of a century that Vitamin A and its derivatives (retinoids) are essential for both normal embryonic development and in the maintenance of adult tissues (Collins and Mao, 2000). Classical data demonstrated...