A 24-year-old male patient with a diagnosis of hepatosplenic schistosomiasis mansoni was admitted to hospital with a history of upper digestive bleeding, pancytopenia and a huge spleen (Figures A and B). Magnetic resonance imaging (Figure C) in a T2 weighted image in the coronal plane (FIESTA), showed splenomegaly and Gamna-Gandy bodies (black arrows) that appeared as foci of low signal intensity or signal void. The portal vein was seen to be patent (white arrow). After a series of tests, he underwent an operation to treat portal hypertension (splenectomy, portal-variceal disconnection and suturing of the esophageal varices). Thirty days after discharge from hospital, he was reexamined at the outpatient clinic and was found to be asymptomatic. Gamna-Gandy bodies (siderotic nodules) consist of organized foci of bleeding within the spleen caused by portal hypertension. These lesions contain fibrous tissue, hemosiderin and calcium. They are also found in cases of portal or splenic thrombosis, hemolytic anemia, leukemia or lymphoma, acquired hemochromatosis and paroxysmal nocturnal hemoglobinuria, and in cases with blood transfusion.