STAT3 IHC Antibody

Ready To Use

Catalog
Number

Size

Price

Availability

IW-PA1108

9 ml

$258

Yes

Description

The transcription factor, signal transducer and activator
of transcription-3 (STAT-3) is the most pleiotropic member
of the signal transducer and activator of transcription
(STAT) family of transcription factors and mediates pivotal
responses for the cytokine family. The mouse STAT3 gene
contains 24 exons and spans 30 kb. The translation
initiation codon is in exon 2, and the stop codon is in exon
24. STAT3 is mapped to
17q21, it contributes to various physiological
processes. Hepatic STAT-3 signaling is thus essential for
normal glucose homeostasis and may provide new therapeutic
targets for diabetes mellitus.

Catalog Number

IW-PA1108

Quantity

9 ml

Host

Rabbit

Clone

Polyclonal

Isotype

IgG

Immunogen

A synthetic peptide corresponding to a sequence at the
C-terminal of human STAT3, identical to the related rat and
mouse sequence.

Purity

Immunogen affinity purified

Conjugate

Unconjugated

Species Reactivity

Human, mouse, rat.
Not tested in other species.

Positive Control

Human mammary cancer

Cellular Localization

Cytoplasmic, nuclear.

Form

Ready to use solution. No further dilution needed. Serum
blocking step should be omitted.