Prizes

Editorial activities

Memberships in editorial boards: Cell Chem. Biol., Scientific Reports

Associate Editor: Synth. Syst. Biotechnol.

Research

Dr Weber is working on genome-based approaches to study and engineer secondary metabolite biosynthetic pathways in microorganisms.
He has pioneered in the development of bioinformatics tools to analyze such pathways. In close collaboration with international collaboration partners, the Weber group develops and provides the web-service of antiSMASH, the world-leading platform for the comprehensive genome-based analysis of secondary metabolite pathways, which is used by scientists from academia and industry all over the world.

The in silico work is directly coupled to experimental work of the group. His group was/is involved in the identification and characterization of various antibiotics biosynthetic pathways, such as streptocollin or kirromycin. The kirromycin pathway codes for a unique discrete PKS acyltransferase, which has a high potential for use in synthetic biology to rationally engineer polyketide biosynthesis pathways to generate novel compounds.

In addition, he is involved in developing molecular tools for the metabolic engineering of actinomycetes, e.g. a CRISPR toolkit for actinomycetes