Ovarian hyperstimulation syndrome

Common Name(s)

Ovarian hyperstimulation syndrome

Ovarian hyperstimulation syndrome (OHSS) is a disorder that usually is caused by taking hormonalmedications to stimulate the development of eggs in the ovaries. In OHSS, the ovaries become swollen and painful. Symptoms usually present within 10 days after taking the medications, though the severity of symptoms varies and may worsen or improve over time. Moderate symptoms include nausea, vomiting, diarrhea, abdominal bloating, mild abdominal pain, or tenderness in the ovary areas. Severe symptoms include dark urine, decreased urinary frequency, shortness of breath, severe abdominal pain, rapid weight gain, tight or enlarged abdomen, or dizziness.

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Advocacy and Support Organizations

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Finding the right clinical trial for Ovarian hyperstimulation syndrome can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ovarian hyperstimulation syndrome" returned 164 free, full-text research articles on human participants.
First 3 results:

The objective of this investigation was to determine if kinase insert domain/vascular endothelial growth factor receptor 2 (KDR/VEGFR2) genetic variation was associated with the development of ovarian hyperstimulation syndrome (OHSS) in patients undergoing controlled ovarian hyperstimulation (COH).

Spontaneous ovarian hyperstimulation syndrome (sOHSS) is a rare event that may result from a FSH-producing pituitary adenoma (FSHoma), activating mutations of the FSH receptor (FSHR), and cross-reactivity of the FSHR to elevated hCG and TSH in the setting of pregnancy or hypothyroidism. ...

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ovarian hyperstimulation syndrome" returned 29 free, full-text review articles on human participants.
First 3 results:

Spontaneous severe ovarian hyperstimulation syndrome-complicated natural pregnancy (SOHSSp) is a rare clinical entity and can be easily misdiagnosed as ovarian tumors. We report a case of SOHSSp in a 26-year-old women with successful delivery, and reviews the clinical data and the ...

Ovarian hyperstimulation syndrome (OHSS) is the most serious complication of controlled ovarian stimulation (COS) as part of assisted reproductive technologies (ART). While the safety and efficacy of ART is well established, physicians should always be aware of the risk of OHSS in ...

The ovarian hyperstimulation syndrome is a major complication of ovulation induction for in vitro fertilization, with severe morbidity and possible mortality. Whereas its pathophysiology remains ill-established, the VEGF may play a key role as well as coagulation disturbances. Risk ...

According to ClinicalTrials.gov there are currently 19 additional "open" studies for "Ovarian hyperstimulation syndrome" (open studies are recruiting volunteers) and 51 "Ovarian hyperstimulation syndrome" studies with "all" status. Visit ClinicalTrials.gov now to view them. Or alternatively, consider TrialsFinder for assistance:

Relief is when you and the right researcher find each other
Finding the right clinical trial for Ovarian hyperstimulation syndrome can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.