技术信息

纯度 & 产品资料

参考文献

GT 949 (GT949) enhances glutamate transport with an EC50 of 0.26 ± 0.03 nM. GT 949 also demonstrates selectivity to EAAT2 and has no effect on glutamate activity mediated by EAAT1 or EAAT3[1].
GT 949 is also tested for its effect on glutamate uptake kinetics in EAAT2-transfected cells. GT 949 enhances glutamate transport in a noncompetitive fashion, with increase in Vmax of about 47%[1].

Solvent & Solubility

In Vitro:

10 mM in DMSO

Preparing Stock Solutions

ConcentrationSolventMass

1 mg

5 mg

10 mg

1 mM

1.8952 mL

9.4758 mL

18.9516 mL

5 mM

0.3790 mL

1.8952 mL

3.7903 mL

10 mM

0.1895 mL

0.9476 mL

1.8952 mL

*Please refer to the solubility information to select the appropriate solvent.