The unintended (and costly) effects due to the introduction of an unrestricted reimbursement policy for atypical antipsychotic medications in a Canadian public prescription drug program: 1996/97 to 2005/06

..To quantify the improvement in health outcomes in patients after total knee replacement (TKR)...

The unintended (and costly) effects due to the introduction of an unrestricted reimbursement policy for atypical antipsychotic medications in a Canadian public prescription drug program: 1996/97 to 2005/06

..The goal of this study was to analyze health-related quality of life (HRQL) data from a Canadian population with type 2 diabetes in order to estimate the disutility associated with experiencing a diabetes-related complication...

Cost-effectiveness analysis of elective endovascular repair compared with open surgical repair of abdominal aortic aneurysms for patients at a high surgical risk: A 1-year patient-level analysis conducted in Ontario, Canada

..The objective of this study was to estimate the cost-effectiveness and cost-utility of elective endovascular aneurysm repair (EVAR) compared with open surgical repair (OSR) in patients at a high risk of surgical complications...

..e., opportunity costs). The objective of this paper is to provide an overview of economic evaluations and how these tools can be used to help inform payers of the best use of scarce health care resources...

Effects of study design and trends for EVAR versus OSR

Robert HopkinsProgram for the Assessment of Technology in Health PATH Research Institute, Department of Clinical Epidemiology and Biostatistics, London Health Sciences Center, London, Ontario, CanadaVasc Health Risk Manag 4:1011-22. 2008

..Finally, we investigate trends over time in EVAR versus OSR outcomes...

Cost-effectiveness of 64-slice CT angiography compared to conventional coronary angiography based on a coverage with evidence development study in Ontario

..To summarize and then assess with a pilot study the use of published best practice recommendations for priority setting during management of multiple healthcare research projects, in a resource-constrained environment...

Cost-effectiveness of reducing wait times for cataract surgery in Ontario

..The objective of the study was to use queuing models to determine the cost-effectiveness of reducing, to target levels, wait times for cataract surgery at the provincial level within 1 to 10 years by increasing treatment volumes...

..While considerable variation was observed among studies, all studies indicated that the costs of treating CVD-related conditions are significant, outlining a convincing case for CVD prevention programs...

..Attempts so far at harmonization have raised numerous legal and practical issues and these must be considered when introducing a more harmonized framework into the existing regulatory and reimbursement arrangements. ..

Validation of Chinese Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) in patients scheduled for total knee replacement

..Our aim was to cross-culturally validate Chinese Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) in patients with knee osteoarthritis (OA) scheduled for total knee replacement in Singapore...

Effect of computer-generated tailored feedback on glycemic control in people with diabetes in the community: a randomized controlled trial

..Obesity is today's principal neglected public health problem, as a rising proportion of adults will succumb to the medical complications of obesity. However, little is known about the burden of obesity in adults living in Ontario...

..Whether HTA is beneficial (supporting timely access to needed technologies) or detrimental depends on three critical issues: when the assessment is performed, how it is performed, and how the findings are used...

Bernice TsoiHamilton, Ontario, Canada and Warsaw, Poland From the Department of Clinical Epidemiology and Biostatistics, The Division of Plastic Surgery, Department of Surgery, and the Surgical Outcomes Research Center, Department of Surgery, McMaster University Programs for Assessment of Technology in Health Research Institute, St Joseph s Healthcare Hamilton and the Second Department of General, Vascular, and Oncologic Surgery, Medical University of WarsawPlast Reconstr Surg 133:234-49. 2014

..The authors compared the safety of tissue expander/implant reconstruction with that of autologous abdominal tissue reconstruction...

The effectiveness of integrated health information technologies across the phases of medication management: a systematic review of randomized controlled trials