Protease of Bacteroides gingivalis

A human salivary peptide that inhibits the protease of Bacteroides gingivalis, as well as clostripain.The antifungal (Candida, Leishmania) activity of histatin 5 involves penetration of the microbial cell, localization in the mitochondria, and inhibition of F1-F0 ATPase, with rapid depletion of ATP.