We describe a new method for measuring skin conductance responses, designed to overcome the problem of overlapping skin conductance responses. The method relies on the assumptions that the underlying sudomotor nerve signal has a shorter time-constant than the skin conductance signal itself, and that the sudomotor bursts arrive as discrete, separated events. By converting the skin conductance signal into a time-series with a shorter time-constant, we are able to extract the separated peaks in the estimated underlying driver signal. The separated driver peaks are then used to re-estimate each individual skin conductance response. The method is automated and applied to a normative database of 735 subjects, for which skin conductance was measured during an auditory oddball paradigm.

en_US

dc.language

eng

en_US

dc.relation.ispartof

J Neurosci Methods

en_US

dc.relation.isbasedon

10.1016/j.jneumeth.2005.02.001

en_US

dc.subject.classification

Neurology & Neurosurgery

en_US

dc.subject.mesh

Sweat Glands

en_US

dc.subject.mesh

Skin

en_US

dc.subject.mesh

Humans

en_US

dc.subject.mesh

Acoustic Stimulation

en_US

dc.subject.mesh

Reaction Time

en_US

dc.subject.mesh

Galvanic Skin Response

en_US

dc.subject.mesh

Electrophysiology

en_US

dc.subject.mesh

Neurophysiology

en_US

dc.subject.mesh

Algorithms

en_US

dc.subject.mesh

Time Factors

en_US

dc.subject.mesh

Signal Processing, Computer-Assisted

en_US

dc.subject.mesh

Adolescent

en_US

dc.subject.mesh

Adult

en_US

dc.subject.mesh

Aged

en_US

dc.subject.mesh

Aged, 80 and over

en_US

dc.subject.mesh

Middle Aged

en_US

dc.subject.mesh

Child

en_US

dc.subject.mesh

Female

en_US

dc.subject.mesh

Male

en_US

dc.subject.mesh

Skin Physiological Phenomena

en_US

dc.subject.mesh

Acoustic Stimulation

en_US

dc.subject.mesh

Adolescent

en_US

dc.subject.mesh

Adult

en_US

dc.subject.mesh

Aged

en_US

dc.subject.mesh

Aged, 80 and over

en_US

dc.subject.mesh

Algorithms

en_US

dc.subject.mesh

Child

en_US

dc.subject.mesh

Electrophysiology

en_US

dc.subject.mesh

Female

en_US

dc.subject.mesh

Galvanic Skin Response

en_US

dc.subject.mesh

Humans

en_US

dc.subject.mesh

Male

en_US

dc.subject.mesh

Middle Aged

en_US

dc.subject.mesh

Neurophysiology

en_US

dc.subject.mesh

Reaction Time

en_US

dc.subject.mesh

Signal Processing, Computer-Assisted

en_US

dc.subject.mesh

Skin

en_US

dc.subject.mesh

Skin Physiological Phenomena

en_US

dc.subject.mesh

Sweat Glands

en_US

dc.subject.mesh

Time Factors

en_US

dc.title

Separating individual skin conductance responses in a short interstimulus-interval paradigm.

en_US

dc.type

Journal Article

utslib.description.version

Published

en_US

utslib.citation.volume

1

en_US

utslib.citation.volume

146

en_US

utslib.location.activity

Netherlands

en_US

utslib.for

1109 Neurosciences

en_US

utslib.for

1109 Neurosciences

en_US

utslib.for

1702 Cognitive Science

en_US

pubs.embargo.period

Not known

en_US

pubs.organisational-group

/University of Technology Sydney

pubs.organisational-group

/University of Technology Sydney/Faculty of Engineering and Information Technology

pubs.organisational-group

/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Systems, Management and Leadership

We describe a new method for measuring skin conductance responses, designed to overcome the problem of overlapping skin conductance responses. The method relies on the assumptions that the underlying sudomotor nerve signal has a shorter time-constant than the skin conductance signal itself, and that the sudomotor bursts arrive as discrete, separated events. By converting the skin conductance signal into a time-series with a shorter time-constant, we are able to extract the separated peaks in the estimated underlying driver signal. The separated driver peaks are then used to re-estimate each individual skin conductance response. The method is automated and applied to a normative database of 735 subjects, for which skin conductance was measured during an auditory oddball paradigm.