During her appearance on "The Tonight Show Starring Jimmy Fallon” tonight, Clinton mocks the Republican presidential candidate’s famous coif -— joking that he has “one strand that he twirls over his head like a soft serve at Dairy Queen.”

Clinton makes the remark during a sketch where she sits down for a phone interview with Fallon, who pretends to be Donald Trump.

"Look, I hate to say it, but I think he’s losing his hair,” Fallon, doing his best Trump impression, tells Clinton over the phone, referring to her democratic opponent, Bernie Sanders.

“Well, at least he doesn’t have just one strand that he twirls over his head like a soft serve at Dairy Queen,” she jokes back.

In the sketch, which will air tonight, Fallon, channeling Trump, also offers campaign advice to Clinton.

“OK, you wanna win? Here’s what you gotta do,” he tells Clinton. "First: Yell. I yell all the time...Next: Pick three things people love and say you hate them.”

"Are you writing all this down?” he asks.

“Hold on, let me just grab my pen,” Clinton responds, as she rolls her eyes, picks up a glass of wine, and takes a sip.

Clinton also jokes about attending Trump’s wedding to Melania Trump, which she and former President Bill Clinton attended.

"I haven’t seen you since my last wedding,” Fallon says to Clinton.

"Well I’m sure I’ll see you at the next one,” she jokes back.

Clinton’s appearance on the "Tonight Show," the same night as the second GOP presidential debate, comes one week after her appearance on "Ellen," where she did the “Nae Nae,” as well as a New York Times report about Clinton’s new attempts to be more “spontaneous.”