custom papers on jyhfr (1 essays)

DM has been
identified which is characterized by a non-immune mediated destruction
of pancreatic islet cells and has been termed as Type 1B DM (Eisenbarth McCulloch , 2009 .
It is a well established fact that type 1 DM is genetically determined .
Several genes have been implicated to play a role in the pathophysiology
of type 1 DM including polymorphisms in HLA-DQalpha , HLA-DQbeta , HLA-DR ,
preproinsulin , the PTPN22 gene , CTLA-4 , interferon-induced helicase , IL2
receptor (CD25 , a lectin-like gene (KIA0035 , ERBB3e , and an undefined...