In brief:
Many

Adults do not gain height once the bones are completely mineralized, but the bones can grow in width.

So wider hands or feet are classic symptoms. Facial bones may enlarge and lead to coarsening of facial features; the jaw may enlarge and protrude. People with acromegaly may also have headaches, diabetes, sleep apnea, heart problems, carpal tunnel, arthritis, & higher risk for cancer.
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