The restructuring continues in .com-ville as Amazon.com, the world’s largest e-tailer, announced yesterday it’s laying off 150 employees, or 2 percent of its staff.

The move comes as investors are looking harder at the bottom line of Internet companies.

The cuts come on the heels of layoffs at e-tailers Value America, boo.com and Beyond.com, whose CEO resigned.

They also follow news that theglobe.com founders Todd Krizelman, 26, and Stephan Paternot, 25, would step down as chief executives of the one-time Wall Street darling, whose stock has been hammered. Theglobe.com promoted COO Dean Daniels to President and are starting to search for a new CEO.

In January, Amazon.com, under Chairman Jeff Bezos, said its record $650 million in holiday season revenue wouldn’t cut losses for the quarter. Amazon.com will disclose the size of its fourth-quarter loss Wednesday.

The job cuts may indicate that new Chief Financial Officer Warren Jenson is making Amazon.com more disciplined, analyst Ron Sachs at Janus Capital Corp. told Bloomberg. Janus is Amazon.com’s largest investor after founder Jeff Bezos.

Amazon.com shares fell $5.25, or 7.8 percent, to $61.68.

At theglobe.com, execs downplayed the changes.

“We’re just as committed as we’ve ever been,” said Paternot. He and Krizelman emphasized they weren’t leaving the company, but would continue to work on product development, international expansion and product acquisition.

The Silicon Alley community site soared ten-fold its first day on the market back in November 1998, although it’s been hovering in the single-digits in recent weeks.

“Todd and Stephan presided over the company when investors saw its valuation decrease ten-fold,” said Mark Mooridian, senior analyst with Jupiter Communications. “Everyone would agree this is a good step to instill investors’ confidence.”

Theglobe.com fell $1.06 to $7.94.

Many community sites, such as Xoom.com, Tripod and AngelFire, were acquired, which analysts expect of theglobe.com as well. “As a stand-alone company, I don’t think it’s viable,” said Mooridian.