This episode we return to our ongoing series on genetic research and sociology inspired by our Summer 2009 feature article on the topic (take a listen to our interview with Thomas Bouchard to hear our first discussion). This time we engage with a slightly different “socio-cultural” perspective and invited sociologist Allan Horwitz to give us his take on how this new science of the gene may medicalize new syndromes. Horwitz also talks about his new controversial book The Loss of Sadness, an examination of the medicalization of depression.