* Amount cited is for Lysine alone and does not include the
acetate salt.
** The minimum daily quantities needed to maintain nitrogen balance in the
healthy adult. (Rose, W.C., The Sequence of Events Leading to the Establishment
of the Amino Acid Needs of Man, Am J. Public Health, 58:2020, 1968.)
*** Histidine is considered essential for patients in renal failure.

Electrolytes and Product Characteristics

Acetate (C2H3O2_)a (mEq/Liter)

113

Protein Equivalent (approx. grams/liter)

52.27

Total Nitrogen (grams/liter)

7.93

Osmolarity (mOsmol/liter)

427

pH (Range)

5.2 (4.5 to 6.0b)

a Includes acetate from acetic acid used in processing
and from Lysine acetate. b Adjusted with acetic acid.

Each 500 mL represents three Rose Units of essential amino acids plus arginine and histidine. The formulas for the individual amino acids present in Aminosyn-RF 5.2% are as follows:

Essential Amino Acids

Isoleucine, USP

(C6H13NO2)

Leucine, USP

(C6H13NO2)

Lysine Acetate, USP

(C6H14N2O2•CH3COOH)

Methionine, USP

(C5H11NO2S)

Phenylalanine, USP

(C9H11NO2)

Threonine, USP

(C4H9NO3)

Tryptophan, USP

(C11H12N2O2)

Valine, USP

(C5H11NO2)

Nonessential Amino Acids

Arginine, USP

(C6H14N4O2)

Histidine, USP

(C6H9N3O2)

The flexible plastic container is fabricated from a specially formulated polyvinylchloride. Water can permeate from inside the container into the overwrap but not in amounts sufficient to affect the solution significantly.

Solutions in contact with the plastic container may leach out certain chemical components from the plastic in very small amounts; however, biological testing was supportive of the safety of the plastic container materials.

Exposure to temperatures above 25°C/77°F during transport and storage will lead to minor losses in moisture content. Higher temperatures lead to greater losses. It is unlikely that these minor losses will lead to clinically significant changes within the expiration period.