A detailed understanding of the RNA content (both coding and noncoding) in a given cell or cell sample is invaluable for understanding differential expression in normal and disease processes. Research using RNA sequencing approaches helps avoid some of the weaknesses associated with using microarrays for RNA profiling. It gives a more quantitative view of the RNA population within a cell (by providing higher sensitivity and a broader dynamic range) and a hypothesis-neutral approach. Interrogate a cell's whole transcriptome, small RNA content, or gene expression profile, using the RNA sequencing solution right for you.

The Ion PGM™ and Ion Proton™ systems provide sequencing-based analysis of all known and novel small RNA transcripts, such as microRNA (miRNA), short interfering RNA (siRNA), and piwi-interacting RNA (piRNA), in a strand-specific, hypothesis-free fashion.