MatchMiner

The input to MatchMiner is two fold: patient-specific genomicand clinical data, and structured eligibility criteria for clinical trials. Patient-specific information includes somaticgenomic events, including mutations, copy number alterations, and structural variants. Basic clinical data such as cancer type, age, and sex extracted from the Electronic Medical Record (EMR) are also utilized.

Structured clinical trial eligibility criteria are specified in the Clinical Trial Markup Language (CTML), and allows the specification of genomic and basic clinical criteria described in clinical trial protocol documents.

The MatchMiner platform matches patient-specific genomic events to clinical trials, and makes the results available to trial investigators and clinicians via a web-based platform.

We are in the process of open-sourcing MatchMiner on GitHub. Please contact us if you are interesting in learning more or would like to collaborate.