Clinical/Scientific Implications Aggressive treatment for brain metastases from lung cancer may be considered in selected patients. The treatment of multiple brain metastasis with stereotactic radiosurgery has not been shown to improve outcome in prospective randomized trials. Radiosurgical treatment of solitary brain metastasis remains under investigation and the results of a recent RTOG trial should shed light on this subject.

Mar 3, 2015 - In patients with non-small cell lung cancer, prophylactic cranial irradiation may help prevent brain metastases, and stereotactic radiotherapy may arrest the growth of lung cancer in frail patients, according to research presented at the 51st Annual Meeting of the American Society for Radiation Oncology, held from Nov. 1 to 5 in Chicago.