BackgroundAnnually over 520,000 newborns die from neonatal sepsis, and 60,000 more from tetanus. Estimates of the effect of clean birth and postnatal care practices are required for evidence-based program planning.

ObjectiveTo review the evidence for clean birth and postnatal care practices and estimate the effect on neonatal mortality from sepsis and tetanus for the Lives Saved Tool (LiST).

MethodsWe conducted a systematic review of multiple databases. Data were abstracted into standard tables and assessed by GRADE criteria. Where appropriate, meta-analyses were undertaken. For interventions with low quality evidence but a strong GRADE recommendation, a Delphi process was conducted.

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Mission

LiST aims to improve the quality of information available to support public health policies and decision making in maternal and child health and nutrition. The focus is on low-income countries, and on research that produces information to improve programs and policies. IIP is a network of scientists based in various institutions, and is housed administratively within the Johns Hopkins Bloomberg School of Public Health.Get more Information