i'm not sure how the cell handles it but glycogen is the hormone responsible for regulating blood sugar by releasing sugar into the blood....or is tha glucagon?? If you want to know what cells specifically would handle it, i think is would be the islets of langerhans..either alpha or beta. This whole thing is part of the pancreas.

Glycogen degradation takes place in the smooth endoplasmic reticulum. The enzyme glucose-6-phosphatase, present here, breaks down glucose-6-phosphate(which results from the release of monomers from the polimer that is glycogen) into glucose molecules. Unfortunately these molecules can not exit the endoplasmic reticulum, so another protein has to take it into the cytoplasm. Once there, it can exit the cell through a GLUT permease.

Andrew, your local cell bio geek

"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter