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IIS not accessing COM references

I have created a web service method that accesses another class For that I had to add a COM reference in my project in Visual Studio.While testing out the webservice in the development server ,everything works fine and the Boston class is accessed.
But when i publish the webservice to IIS,I cant access the class for which I had added the COM reference.
Do you need to add some settings or some other ocnfigurations while deploying to IIS to access COM references.