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Re-launch Vivado and a new layout file will be created with default settings.

Note: The vivado.ini and the default.layout files have been found to be out of sync or corrupt on some user systems.

Therefore, they are specifically mentioned above.

To be thorough, you could rename the entire directory (for example C:\Users\(Username)\AppData\Roaming\Xilinx\vivado\2013.4_bac).

Ensuring that the Microsoft Redistributable runtime library has been properly installed:Note: If the redistributable library is missing, the failed launch is usually accompanied by an application error message window that states; "The application failed to initialize properly (0xc0150002). Click on OK to terminate the application."