In this chilling adaptation of the best-selling novel by Thomas Harris, the astonishingly versatile director Jonathan Demme crafted a taut psychological thriller about an American obsession: serial murder. As Clarice Starling, an FBI trainee who enlists the help of the infamous Hannibal “the Cannibal” Lecter to gain insight into the mind of another killer, Jodie Foster subverts classic gender dynamics and gives one of the most memorable performances of her career. As her foil, Anthony Hopkins is the archetypical antihero—cultured, quick-witted, and savagely murderous—delivering a harrowing portrait of humanity gone terribly wrong. A gripping police procedural and a disquieting immersion into a twisted psyche, The Silence of the Lambs swept the Academy Awards (best picture, best director, best screenplay, best actress, best actor) and remains a cultural touchstone.