The original SETI client was a non-BOINC software exclusively for SETI@home. As one of the first volunteer grid computing projects, it was not designed with a high level of security. Some participants in the project attempted to cheat the project to gain "credits", while some others submitted entirely falsified work. BOINC was designed, in part, to combat these security breaches.[8]

The BOINC project started in February 2002 and the first version was released on April 10, 2002. The first BOINC-based project was Predictor@home launched on June 9, 2004. In 2009, AQUA@home deployed multi-threaded CPU applications for the first time,[9] followed by the first OpenCL application in 2010.

In essence, BOINC is software that can use the unused CPU and GPU cycles on a computer to do scientific computing—what one individual does not use of his/her computer, BOINC uses. In late 2008, BOINC's official website announced that NVIDIA (a leading GPU manufacturer) had developed a system called CUDA that uses GPUs for scientific computing. With NVIDIA's assistance, some BOINC-based projects (e.g., SETI@home, MilkyWay@home) now have applications that run on NVIDIA GPUs using CUDA. Beginning in October 2009, BOINC added support for the ATI/AMD family of GPUs also. These applications run from 2× to 10× faster than the former CPU-only versions. In 7.x preview versions, GPU support (via OpenCL) was added for computers using Mac OS X with AMD Radeon graphic cards.

BOINC consists of a server system and client software that communicate with each other to distribute, process, and return workunits.

A BOINC Account Manager is an application that manages multiple BOINC project accounts across multiple computers (CPUs) and operating systems. Account managers were designed for people who are new to BOINC or have several computers participating in several projects. The account manager concept was conceived and developed jointly by GridRepublic and BOINC. Current account managers include:

BAM! (BOINC Account Manager) (The first publicly available Account Manager, released for public use on May 30, 2006)

GridRepublic (Follows the idea of keep it simple and keep it neat when it comes to account management)