Depression during pregnancy is highly likely to recur after delivery, Mass General researchers have determined. The finding implies that maternal depression is a major confounder when assessing the influence of prenatal antidepressant exposure on child neurodevelopment.

Ketamine has long been used as a general anesthetic, but more recent research has found it to be effective in rapidly relieving depression symptoms when given at low, subanesthetic doses. New research identifies two optimal dosages.

Unlike traditional antidepressants, ketamine may be similarly effective in both anxious and nonanxious patients with treatment-resistant depression, according to a secondary analysis of a randomized, controlled clinical trial.

Joan A. Camprodon, MD, PhD, is chief of Mass General's Division of Neuropsychiatry, director of the Transcranial Magnetic Stimulation (TMS) Clinical Service and director of the Laboratory for Neuropsychiatry & Neuromodulation. In this video, he discusses creating individualized treatments using TMS for patients with depression and using TMS to reduce suicide risk in other patients. He also discusses the use of transcranial direct current stimulation (tDCS) as a precognitive therapy to improve executive function in patients across the neurological and psychiatric spectrum.

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