During a major outbreak the Black Death from 1348 to 1350; Clement did what he could for sufferers. He fought the wave of anti-Semitism brought on by the plague, and helped protect Jews. Fought with Holy Roman Emperor Louis IV over the annulment of Margaret Maultasch’s marriage, but was chosen a “Knight of Rome”. Condemned the Flagellants. Defended the Mendicant friars in 1351 against the accusations of secular prelates. Clement spent extravagantly, held an elegant court, patronized artists, favored his relatives, and was pro-French in all matters; most of the 25 cardinals he created were French, and 12 were his relatives.