..Our data indicates that screening compounds for the ability to affect transsulfuration in cultured cell models must take proliferation status into account to avoid masking regulatory interactions that may be of significance in vivo...

..Thus, elevated MMA concentration may be associated with hearing loss in older adults. However, short-term B12 supplementation was unrelated to improvements in hearing status in B12-deficient individuals...

Hyperhomocysteinemia and vitamin B-12 deficiency in elderly using Title IIIc nutrition services

Total homocysteine is associated with white matter hyperintensity volume: the Northern Manhattan Study

Clinton B WrightDepartment of Neurology, Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY, USAStroke 36:1207-11. 2005

..White matter hyperintensities may be a risk factor for both, but studies of the relationship between tHcy and quantitative measures of white matter hyperintensity volume (WMHV) are lacking, especially in minority populations...