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Sadism personality disorder is a psychic disorder. The afflicted one reaches to some mental, physical and sexual satisfaction by making others suffer mentally, physically and sexually. Therefore, many behaviors that are based on sadism are considered as criminal acts. What are investigated in this article encompass:Nature, reason and circumstances of sadism personality disorder, concept of crime of sadism, the answer to the question why all the crimes cannot be considered sadistic and quality of criminal responsibility of the perpetrators afflicted to sadism that finally lead to investigation of sadistic crimes against person, its social aspects and additionally crimes against property, ownership, public safety and security that are based on sadism personality disorder. This abstract ends by considering the importance of sadism crime prevention and necessity of attention to the difference of this crime with ordinary ones by presenting practical suggestions.