Excellent news. Will we actually be able to convince people to take it once trials are complete?

Seeing the difference between a 70% mortality and 30% mortality rate will be quite convincing to most folks out there. It's like with polio vaccination, for example. The folks who are spreading nonsense now certainly weren't around in the fifties and sixties to see what a difference it made, and those who were certainly aren't participating in the antivax madness.Seeing this sort of thing saving lives left, right and centre tends to make people set aside ideology in favour of, you know, not dying.

Treatments based on monoclonal antibodies that I've seen tend to be prohibitively expensive - any word on whether that's true for these two experimental drugs, or will/would be if they were produced at scale?

Excellent news. Will we actually be able to convince people to take it once trials are complete?

Seeing the difference between a 70% mortality and 30% mortality rate will be quite convincing to most folks out there. It's like with polio vaccination, for example. The folks who are spreading nonsense now certainly weren't around in the fifties and sixties to see what a difference it made, and those who were certainly aren't participating in the antivax madness.Seeing this sort of thing saving lives left, right and centre tends to make people set aside ideology in favour of, you know, not dying.

Nothing like a concrete, real-world example happening now to bring these things to the fore. I have a feeling that the vast majority of anti-vaxxers would have a completely different opinion if they'd seen the real-world effects of many of the diseases that are now mostly eradicated, and then seen that completely disappear with the introduction of the vaccines.

Modern medicine as pretty much a miracle in its own right.

I hope that the heroes and heroines working on an Ebola vaccine come up with something equally as effective.

Edit: To clarify - I hope the eventual Ebola vaccine is as effective as expected, and like other diseases of bygone eras, effectively become eradicated.

Excellent news. Will we actually be able to convince people to take it once trials are complete?

Seeing the difference between a 70% mortality and 30% mortality rate will be quite convincing to most folks out there. It's like with polio vaccination, for example. The folks who are spreading nonsense now certainly weren't around in the fifties and sixties to see what a difference it made, and those who were certainly aren't participating in the antivax madness.Seeing this sort of thing saving lives left, right and centre tends to make people set aside ideology in favour of, you know, not dying.

Nothing like a concrete, real-world example happening now to bring these things to the fore. I have a feeling that the vast majority of anti-vaxxers would have a completely different opinion if they'd seen the real-world effects of many of the diseases that are now mostly eradicated, and then seen that completely disappear with the introduction of the vaccines.

Modern medicine as pretty much a miracle in its own right.

I hope that the heroes and heroines working on an Ebola vaccine come up with something equally as effective.

The last line in the article says:"Earlier work in the outbreak suggested that an experimental vaccine against the virus is 97.5% effective."

I'm not sure they want to make the vaccine less effective such that it is equal to the 70% effectiveness of the anti-virals.

Excellent news. Will we actually be able to convince people to take it once trials are complete?

Seeing the difference between a 70% mortality and 30% mortality rate will be quite convincing to most folks out there. It's like with polio vaccination, for example. The folks who are spreading nonsense now certainly weren't around in the fifties and sixties to see what a difference it made, and those who were certainly aren't participating in the antivax madness.Seeing this sort of thing saving lives left, right and centre tends to make people set aside ideology in favour of, you know, not dying.

Nothing like a concrete, real-world example happening now to bring these things to the fore. I have a feeling that the vast majority of anti-vaxxers would have a completely different opinion if they'd seen the real-world effects of many of the diseases that are now mostly eradicated, and then seen that completely disappear with the introduction of the vaccines.

Modern medicine as pretty much a miracle in its own right.

I hope that the heroes and heroines working on an Ebola vaccine come up with something equally as effective.

The last line in the article says:"Earlier work in the outbreak suggested that an experimental vaccine against the virus is 97.5% effective."

I'm not sure they want to make the vaccine less effective such that it is equal to the 70% effectiveness of the anti-virals.

Teach me to make a vague statement in direct response to a comment about the effects of the Polio vaccine.

I've edited to clarify that I hope it is indeed as effective as successful vaccines for other diseases, rather than diminishing its capabilities to the anti-virals discussed in the article.

Excellent news. Will we actually be able to convince people to take it once trials are complete?

I have little doubt about it.Given the place these outbreaks usually happen, they can see first hand the effectiveness of such measures.

Only in countries where you don't see many outbreaks and people dying like flies or getting out with heavy permanent damages -you know, countries where vaccines have been proven to be the most effective, ironically - you can see movements against vaccines.

ZMapp™ is composed of three “humanized” monoclonal antibodies manufactured in plants, specifically Nicotiana. It is an optimized cocktail combining the best components of MB‐003 (Mapp) and ZMAb (Defyrus/PHAC).

Isn't the survival rate already high? It seems very strange that there are new cases here and there all the time. As if most people would only spread the virus without symptoms.

The survival rate is much higher in first-world countries with massive ICU-level resources. And like many diseases, the virus has a reservoir outside of human populations as well - so infection can still occur without direct human-to-human contact.

new vaccines probably contains nanites/nanotechnology in them, I helped developing such cures in secret army cyborg one programme, I can remember I was in big town chemical battle where foreign secret service spread chemicals able to create heart stroke and one man fell down on the pavement dead, I was instructed to pass the area as a cyborg with nanites in blood and I felt only small heart pain, but I survived... I can celarly remember the first aid vehicle helping dead man stroke in this fight.. It is caused the way sympaticus and parasympaticus are set up by spinalis nanites and it bans the heartbreak under chemical attack, you feel just a breeze in the body. But I paid a lot helping scientists to save these people, the liver is ill after all but we live.

new vaccines probably contains nanites/nanotechnology in them, I helped developing such cures in secret army cyborg one programme, I can remember I was in big town chemical battle where foreign secret service spread chemicals able to create heart stroke and one man fell down on the pavement dead, I was instructed to pass the area as a cyborg with nanites in blood and I felt only small heart pain, but I survived... I can celarly remember the first aid vehicle helping dead man stroke in this fight.. It is caused the way sympaticus and parasympaticus are set up by spinalis nanites and it bans the heartbreak under chemical attack, you feel just a breeze in the body. But I paid a lot helping scientists to save these people, the liver is ill after all but we live.

Uuuuh since when did the comment section become a place to write dystopian science fiction?

Excellent news. Will we actually be able to convince people to take it once trials are complete?

Seeing the difference between a 70% mortality and 30% mortality rate will be quite convincing to most folks out there. It's like with polio vaccination, for example. The folks who are spreading nonsense now certainly weren't around in the fifties and sixties to see what a difference it made, and those who were certainly aren't participating in the antivax madness.Seeing this sort of thing saving lives left, right and centre tends to make people set aside ideology in favour of, you know, not dying.

Nothing like a concrete, real-world example happening now to bring these things to the fore. I have a feeling that the vast majority of anti-vaxxers would have a completely different opinion if they'd seen the real-world effects of many of the diseases that are now mostly eradicated, and then seen that completely disappear with the introduction of the vaccines.

Modern medicine as pretty much a miracle in its own right.

I hope that the heroes and heroines working on an Ebola vaccine come up with something equally as effective.

Edit: To clarify - I hope the eventual Ebola vaccine is as effective as expected, and like other diseases of bygone eras, effectively become eradicated.

Agree with your sentiment. However modern medicine is science. These days science needs as much support as it can get.

Longevity and distribution solutions aren't of much help when there's nothing to distribute or expire.

Coming up with a cure first seems like the correct priority.

No,, No, no, one MUST have a complete solution before anything is done. That is why we can't address climate change, because we can't get everyone to agree to a complete solution. I mean that is just so obvious. One would never seek pain relief after a cancer diagnosis until a complete cure and payment method for treatment had been obtained would one?....Oh wait.......

While this is all great news and some progress to see, these tests are kinda hard to process when you image how they work: Imagine, you'll get a treatment, but you're getting the less effective one. Noone knows before, and if you die, you're just a number on the negative side...It's all good - all of them work in some way. But don't you wish in such a situation to get the most effective one?That's a real ethical issue...

Edit: If you downvoted this, I'm sorry, then you probably don't understand my deeper thought: I wish nobody to be in this situation. You're a hero either surviving it or not. But I'd rather like and wish everybody to survive it.Really, get your itchy fingers under control!

While this is all great news and some progress to see, these tests are kinda hard to process when you image how they work: Imagine, you'll get a treatment, but you're getting the less effective one. Noone knows before, and if you die, you're just a number on the negative side...It's all good - all of them work in some way. But don't you wish in such a situation to get the most effective one?That's a real ethical issue...

There’s no ethical issue in learning after the fact that the treatment you used was not the most effective treatment. If there were, no treatment would be ethical, because we’ll come up with better therapies later.

The ethical issue is when you have a therapy like ZMapp that in a small trial seems to maybe help, so now do you keep experimenting with a control of no drug therapy (with abysmal survival rates), or do you start treating everyone?

Now that we have better drugs, the ethical issue of relying on a not-ethically-testable therapy is gone.

Excellent news. Will we actually be able to convince people to take it once trials are complete?

Seeing the difference between a 70% mortality and 30% mortality rate will be quite convincing to most folks out there. It's like with polio vaccination, for example. The folks who are spreading nonsense now certainly weren't around in the fifties and sixties to see what a difference it made, and those who were certainly aren't participating in the antivax madness.Seeing this sort of thing saving lives left, right and centre tends to make people set aside ideology in favour of, you know, not dying.

Nothing like a concrete, real-world example happening now to bring these things to the fore. I have a feeling that the vast majority of anti-vaxxers would have a completely different opinion if they'd seen the real-world effects of many of the diseases that are now mostly eradicated, and then seen that completely disappear with the introduction of the vaccines.

Modern medicine as pretty much a miracle in its own right.

I hope that the heroes and heroines working on an Ebola vaccine come up with something equally as effective.

Edit: To clarify - I hope the eventual Ebola vaccine is as effective as expected, and like other diseases of bygone eras, effectively become eradicated.

Agree with your sentiment. However modern medicine is science. These days science needs as much support as it can get.