The impact of modern medicine on the human condition can’t be underestimated. From antibiotics to vaccines, medicine has changed the way our bodies work, answered deadly questions, and promised faster cures.

But it’s not simple. Drug development is rife with tension. It costs a lot of money, and takes a long time. Most things fail. But when they succeed, they can make a tremendous difference in people’s lives.

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Where will the next breakthroughs come from? How will we pay for them? Who decides who gets them?