The song is about TV evangelists and false messiahs making money off of
people's faith.

Before the premiere and various times before playing Leper, James would
dedicate this song
to "Jim and Tammy". Most probably didn't get it, but it's a joke - Jim and Tammy Fay Baker
were TV
evangelists
who embezzeled millions of dollars in charity money.

Dave Mustaine claims he wrote the song's main riff and wasn't credited.
Don't know if it's true.