The network computing platform is an advanced means to realize the intelligent service of seismic information, but it is still blank in the field of disaster prevention and mitigation engineering.This paper uses Java Web technology and Matlab programming to design and complete an online interactive network computing platform based on the new generation seismic response analysis method developed by Chinese scholars.According to user requirements and computing characteristics, the platform adopts B/S mode and three-tier architecture to facilitate maintenance and expansion; MySQL database is used to complete data storage, and multi-threaded concurrent computing is supported; MD5 encryption method is used to ensure data security. Using Java and Matlab mixed programming, the two-dimensional drawing is realized quickly and easily, and the calculation efficiency is greatly improved. The platform has been used by hundreds of users at home and abroad for hundreds of times, which proves that the design method is reasonable and the operation is relatively good. The platform is used to solve the problem that the previous seismic response analysis method of the national soil construction project can not solve. It has also accumulated experience in the establishment of other advanced computing platforms in the field of disaster prevention and mitigation.