Abstract: A review. Stimuli-responsive polymers are capable of translating changes in their local environment to changes in their chem. and/or phys. properties. This ability allows stimuli-responsive polymers to be used for a wide range of applications. In this review, the authors highlight the anal. applications of stimuli-responsive polymers that were published over the past few years with a focus on their applications in sensing/biosensing and sepns. From this review, the authors hope to make clear that while the history of using stimuli-responsive polymers for anal. applications is rich, there are still a no. of directions to explore and exciting advancements to be made in this flourishing field of research. [on SciFinder(R)]