...To this day, there is still controversy over when to operate on these fixed nasal deformities acquired during midfacial growth. The painting by Helnwein, entitled "Mean Child", depicts a terrified child who has just undergone a reconstructive operation to form a new nose from a frontal flap (Fig. 46). Blood drips from the tubes projecting from the reconstructed nose. A purulent scrap of granulation is seen in the left medial canthus, while a fresh scar from which the sutures have just been removed stretches from the angle of the mouth to the left ear. The flowered wallpaper in the background contains these words: disobedience allowed, taking pleasure in punishments, unchaste things, and other words which are connected with lines to the pathological alterations in the face. Do these harken back to the mediaeval belief that sickness is a punishment for greater or lesser human failings?
Artists:
George Grosz, Gottfried Helnwein, Albrecht Dürer, Rembrandt, Peter Paul Rubens, William Hogarth, Otto Dix, Velásques, Hans Holbein the Younger, Bernard van Orley, Vrubel, Jacob Jordaens, Juan Carreno de Miranda, George Catlin, Jan Provoost, Honoré Daumier , Heinrich Zille, Wilhelm Busch, , Gaetano Guilio Zumbo, Manfred Deix, Simone Martini, Cornelis Cornelisz van Haarlem, Marc Chagall, Chicotot, Laurence Sterne, Utamaro, Ferdinand Bol, Master of the Wenemaer Triptych, Liberale da Verona, Jules Lenepveu, Alexandrowitsch Wssjewoloshskij, and Ancient Egypt-, Phoenician-, Roman-, Greek- and Mayan -artists.

In the last century, the removal of the obstructing adenoids had become very popular like this unpleasant method to examine a child's nasopharynx by the physician (Fig. 38). Here the aggressive examination had been photographed for a German ENT book. The physician is probing the child's mouth, thrusting his index finger deeply into the throat. In order that the child cannot bite the palpating finger, the examiner's other hand pushes the skin of the child's cheeks between the rows of teeth.

The model head of the eldest daughter Merit-Amen (Fig. 3) shows the deformed head best. According to an ancient source King Akhenaten ordered his chief sculptor, Bek, to portray him in a way different from the standard representation. Thus, other interpretations concerning the King's distorted head seem to be somewhat speculative.Fig. 3.

The model head of the eldest daughter Merit-Amen (Fig. 3) shows the deformed head best. According to an ancient source King Akhenaten ordered his chief sculptor, Bek, to portray him in a way different from the standard representation. Thus, other interpretations concerning the King's distorted head seem to be somewhat speculative.

Albrecht Dürer

Albrecht Dürer

Until today, magical and fantastical ideas about positive and damaging influences have dominated the imagination of pregnant women concerning their unborn babies. The Swabian artist of this paper-maché (Fig. 8) gives us an idea of his "3-D Magnetic Resonance Image" of the foeti around 1440..Fig. 8.

Therefore, one had to wait until the baby was born and, as this father of healthy twins exhibits, everybody was happy when they heard the newborn crying loudly (Fig. 9)..Fig. 9.

In the Middle Ages, a test of viability was to demonstrate the newborn's ability to cry so loudly that it could be heard in the four corners of a room. This was handed down in the illuminated manuscript of the "Sachsenspiegel", an illustrated book of law of Saxonia. Here, it reads: "Born alive is any child, if one can hear its voice at the four walls of the house". The half figures in the corners (Fig. 10) represent the statement that "one can hear its voice at the four walls of the house". The mother emphasizes this by pointing with her index finger. This is also one early depiction of the ability to hear by holding the ear forward with the index finger into the direction of the sound..Fig. 10.

At one time, a common method of disposing unwanted and handicapped children was drowning, as shown in this illustration from Dijon (Fig. 11). Here, three women of various classes have the same goal: to hurl their unwanted children off a bridge into the swirling torrent below. The child of the woman to the right is almost drowned; only its legs and right arm are still rising from the water. The woman with the simple, blue dress is in the act of dropping her infant, weighed down with a stone, from the bridge while the richly dressed lady to the left is just stepping onto the bridge with her child in arm, in order to dispose of it "cleanly" in the river..Fig. 11.

Saint Blaise, an ancient physician in Sivas in Asian Turkey, is known as a guardian of the neck: "Blaise's blessings". He performed several miracles including saving a child who had choked on a fish bone. Before his beheading, Blaise beseeched God that anyone with a disease of the throat should be healed if he prayed to the saint with the words: "Blaise, martyr and servant of Christ, said 'either go up or go down'". This recommendation goes back to the Greek physician Aetius (5th century AD) who left the text in Latin: "Blasius martyr et servus Christi dixit: aut ascende, aut descende". Saint Blaise is surrounded by putti (Fig. 13) that display his attributes: the crozier, candle, and book. In front of the bishop there lies a putto who is being menaced by a huge toad crouching on his neck. This is certainly a very original allegory of a disease entity of the neck..Fig. 13.

Since antiquity, ex-votos have been testimonies of faith in the form of bodily organs or pictures which were offered both as a plea for help and as thanksgiving. In this votive image (Fig. 14), the resuscitation of a girl is depicted who has fallen into a washtub. With the help of a little tube, a physician aspirates water from the mouth and pharynx. This salvation of the little girl seems to be ascribed to the Mother of God, who is depicted in a cloud..Fig. 14.

The intubation of a diphtheric infant, 100 years later, is performed by a physician without the help of a saint as shown in this oil painting by the French artist Chicotot (Fig. 15)..Fig. 15.

The injury of the newborn's nose during the act of birth and its repair was described by Laurence Sterne in his book: "The Life and Opinions of Tristam Shandy, Gentleman" (Fig. 16). We read: "This unfortunate drawbridge of yours, quoth my father... God bless your honour, cried Trim, 'tis a bridge for master's nose. In bringing him into the world with his vile instruments, he has crushed his nose, Susannah says, as flat as a pancake to his face, and he is making a false bridge with a piece of cotton and a thin piece of whalebone out of Susannah's stays, to raise it up". We can see that the method of nasal reposition in newborns has remained the same, though with different instruments..Fig. 16.

Otto Dix

1927

Artists have depicted dwarfism, as in achondroplasia, for thousands of years. Fig. 22 shows an achondroplastic dwarf from the Late Period of Ancient Egypt with the typical frontal bossing, saddle nose, and short, deformed extremities..Fig. 22.

In 1920, Otto Dix depicted the same disease in his painting "Praha Street" (Fig. 23)..Fig. 23.

In the painting "St. Bernard heals the sick" (Fig. 24), we see one of the diseased children holding a little bell in his right hand with his thumb and index finger. The other fingers seem syndactylic. The child's head is remarkable for its brachycephaly with frontal bossing, exorbitism and hypertelorism, the flat bridge of the short nose, and its deep root. These anomalies of the head, together with the malformation of the right hand, would suggest that the child suffered from Apert's syndrome..Fig. 24.

In this watercolor, the Russian painter Alexandrowitsch Wssjewoloshskij caricatured a mother and her baby at the court of the tsar (Fig. 26) when he depicted the inherited progenia and enlarged lower lip, which were well-known characteristics of the Habsburgian dynasty..Fig. 26.

An unknown artist painted Emperor Charles V at the age of 45 with marked Habsburgian characteristics, partly camouflaged by the beard (Fig. 29)..Fig. 29.

Among the works of the Russian painter Vrubel, I found the portrait of a sad boy with left cleft lip and nasal stenosis sitting in a baby carriage (Fig. 31). This is a very personal statement of a father and painter, whose child was born with an incomplete cleft lip and deformed left nasal wing..Fig. 31.

At the same time, Juan Carreno de Miranda painted this portrait of the 5-year-old Eugenia Martenez who also looks as if she suffered from Prader-Willi syndrome (Fig. 35)..Fig. 35.

One of the pioneers of the 19th century who documented sleep-disturbing snoring in children was George Catlin, lawyer, civil engineer and noted painter of the American Indian. This drawing of a snoring boy (Fig. 36) is part of the booklet "Shut Your Mouth and Save Your Life". The comment to this drawing reads: "Children, I have said, are not born hunchbacks, but a habit of sleeping thus, in the varying temperatures of the night, might make them such. Infants are not born idiots or lunatics, but a habit of sleeping thus, in sudden change of weather, would tend to make them so"..Fig. 36.

A massive adenotonsillar hyperplasia, untreated in childhood, may result in a so-called long-face syndrome as can be seen in the features of this adolescent depicted by Jan Provoost (Fig. 37)..Fig. 37.

In the last century, the removal of the obstructing adenoids had become very popular like this unpleasant method to examine a child's nasopharynx by the physician (Fig. 38). Here the aggressive examination had been photographed for a German ENT book. The physician is probing the child's mouth, thrusting his index finger deeply into the throat. In order that the child cannot bite the palpating finger, the examiner's other hand pushes the skin of the child's cheeks between the rows of teeth..Fig. 38.

This brutal method of examination is seen through the eyes of the Austrian artist Helnwein in his painting, "The Operation" (Fig. 39). A girl, her left hand tied down, lies supine on an operating table, fully clothed. A tight leather belt about her thorax and arms has committed her to immobility. The gigantic steel tube, which coming down from above has filled the child's mouth, underscores this state of being tied down. The girl is forced, defenceless and totally awake, to endure this torture. In the background, we see a similar scene as in the photograph of the ENT textbook..Fig. 39.

Honoré Daumier

In the 1920s, Heinrich Zille, a popular caricaturist in Berlin, depicted the most effective way to remove the snot from one's sister's nose (Fig. 41)..Fig. 41.

Wilhelm Busch has drawn an allergic response of the external nose to a bee sting in his comic strip series "The small thieves of honey" (Fig. 42). Peter and John wanted to satisfy their sweet tooth by stealing honey, but the bees stung into their noses, which resulted in an allergic edema..Fig. 42.

The father tried to soothe them with cold water (Fig. 43). In vain, the boys could not eat their beloved dumplings, thus, the father had to call for the blacksmith of the village who removed the stingers with a huge pliers..Fig. 43.

The physician put a black plaster on top of their noses (Fig. 44), and a happy ending came after a deep sleep when Peter and John could again enjoy their dumplings..Fig. 44.

Artists also depicted the sequelae of an early nasal injury. Rembrandt, for instance, portrayed "The girl at a window" who has got a crooked hypoplastic nose to the left (Fig. 45, left) and Otto Dix painted the "Boy from the Working Class" with a bony deviation of the nasal pyramid, an asymmetric face, squinted eyes, a prominent left ear and a hopeless facial expression as symbols of the lad's social status during the hunger years following World War I (Fig. 45, right)..Fig. 45.

To this day, there is still controversy over when to operate on these fixed nasal deformities acquired during midfacial growth. The painting by Helnwein, entitled "Mean Child", depicts a terrified child who has just undergone a reconstructive operation to form a new nose from a frontal flap (Fig. 46). Blood drips from the tubes projecting from the reconstructed nose. A purulent scrap of granulation is seen in the left medial canthus, while a fresh scar from which the sutures have just been removed stretches from the angle of the mouth to the left ear. The flowered wallpaper in the background contains these words: disobedience allowed, taking pleasure in punishments, unchaste things, and other words which are connected with lines to the pathological alterations in the face. Do these harken back to the mediaeval belief that sickness is a punishment for greater or lesser human failings?.Fig. 46.

From the beginning of the 16th century, the use of a padded cap to prevent injuries of the head in infants during their period of learning to walk is documented in medicine and arts. In 1577, the physician Omnabonus Ferrarius recommended the head pad in his book on Pediatrics (Fig. 47): "... because it often happens to the child to fall down while beginning to walk. Therefore, to prevent injuries to the face and head, I recommend to put upon the child's head a round ring each day, made from wrapped linen or from buck's skin and filled with wadding, divided into four parts like a king's crown..." An outstanding example of prophylactic medicine more than 400 years ago!.Fig. 47.

In this ex-voto (Fig. 51), Saint Notburga with her typical symbols (sheaf, sickle, bunch of keys, bucket for milk) is asked for help with a child with nosebleed. The girl is sitting in an upright position on a stool, the head slightly bent forward so that the blood from her nose cannot spoil her clothes..Fig. 51.

Heinrich Zille from Berlin, mentioned above, described a boy with a nosebleed who is weeping because he has injured his nose in a soccer game and returns to his mother in need of consolation (Fig. 52)..Fig. 52.

Patron saints can be helpful – in many ways. Their multifacetted assistance is shown, for example, in the "Blessed Agostino Novello Altarpiece", of Simone Martini in Siena (Fig. 54). The altarpiece is composed of a central area with Agostino and of two side areas with Agostino's miracles. I would like to focus on two miracles: a child falling out of his bed (right side, bottom) and a child being attacked by a wolf when it was playing outside the gates of the city (left side, top). The scene of the falling child shows a very early depiction of epistaxis of an infant, dated 1324 AD. We look into the bedroom of a house where a pendulous bed is hanging, the torn suspension rope having made the infant fall out. A woman in a pink dress is calling for help by turning her eyes to Agostino, who is floating down through the air from the upper right corner..Fig. 54.

Very nature-like is this small polychrome semi-relief of Phoenician ivory from the 8th century BC in the British Museum (Fig. 57), part of a furniture ornament from Calah (Nimrud). In this semi-relief, a lioness has thrown an Ethiopian boy to the ground and is ripping open his throat..Fig. 57.

The horrific abuse and slaughter of children by warriors is certainly as old as mankind itself. The archetype in Christian iconography is seen in "The Slaughter of the Innocents at Bethlehem", though the event is not at all historical. From the fifth century on, there are many depictions of how soldiers stab the children who also die due to neck injuries. In this example from Baroque, created by the leading mannerist among Dutch painters, Cornelis Cornelisz van Haarlem, the accuracy of the artist's eye is visible in this detail (Fig. 58) from his painting "The Murder of the Innocents". Alongside the deadly blade, fine drops of blood spray in a narrow gush from the infant's short neck in whose face there is nothing but pain and fear..Fig. 58.

An illustration in the manuscript "Book of the Deeds" from the 15th century (Fig. 59) provides details of an inflammatory neck tumor suffered by a child of Rouen in 1281. The inscription tells that the tumor, which started the size of a chicken's egg, had ulcerated, became purulent and expanded as far as the larynx, then to the contralateral side of the neck and even into the armpits. The large lesion became clear of infection, but could not be healed..Fig. 59.

In 1731, more than 20,000 Protestants were driven from the Archdiocese of Salzburg on account of their confession and were resettled in The Netherlands, Germany, and even in Georgia in the United States. As in many Alpine areas, goiter was endemic in the region of Salzburg. An example is shown with this engraving of the emigrant Steinbacher with her three children, of whom at least one girl has as much sign of a goiter as her mother (Fig. 60)..Fig. 60.

The "battered-child syndrome" is not an invention of our time. As early as the Middle Ages, we find documents telling of insane or drunken parents who injured their children with blows or even killed them. In 18th century England, many children were injured by their drunken parents. It was again William Hogarth who, as an artist, tried to fight against alcohol as here in the engraving "Gin Lane" (Fig. 61). Between 1730 and 1749, approximately 75% of all baptised children under 5 years died, very often due to alcohol embryopathy and early abuse of gin. Probably this microcephalic infant, thrown down to death by her drunken mother, had this symptom of alcohol embryopathy..Fig. 61.

In this detail of the right edge of the engraving (Fig. 62), we see how a mother is feeding her infant with gin, and how two young orphan girls are drinking gin for breakfast, because they were too poor to get normal food..Fig. 62.

The vertiginous effect of alcohol upon a child can be seen in this detail of a sarcophagus from the 3rd century AD where a staggering drunken boy, with a bunch of grapes in his hand, is supported by another boy (Fig. 63)..Fig. 63.

Vertigo can also be a symptom of a diseased ear, our last topic. Seven women carved in stone are part of the wall decoration in the entrance hall of the cathedral in Freiburg and represent the ideal of Christian education. One of them (Fig. 64, left) keeps a bundle of rods in her right hand ready to give the standing child the stick because he has not learnt his lesson unlike the sitting boy who is reading a book. She punishes the boy by pulling his left auricle, a method that I found as early as in the 4th century BC in a Greek terracotta from Tanagra. In 1841, Honoré Daumier caricaturized this instrument of education in his lithograph "How to Finally Get a Young Man to be Respectful to his Parents" (Fig. 64, right)..Fig. 64.

Marc Chagall has also depicted this pulling at children's ears in an etching (Fig. 65, left) from the series illustrating Gogol's "Dead Souls" (1924–1926) as commentary to the following text: ...and then there is that similarly well-known, but nonetheless unpleasant feeling when, after these words, his earlobes were painfully twisted by his father's fingers with their long nails. "Also, comics like to depict this method of education as we can see from the naughty boy Jeremiah in Lucky Luke's series "California or Death" (Fig. 65, right)..Fig. 65.

The removal of ear wax from a child's ear is rarely depicted in art as here in a woodcut of the Japanese painter Utamaro (Fig. 66)..Fig. 66.

Ferdinand Bol, a pupil of Rembrandt, depicted an example of a prominent ear (Fig. 67, left). The boy is also suffering from favus. Otto Dix painted another example of prominent ears in his work "Matchbox-seller" nearly 400 years later (Fig. 67, right)..Fig. 67.

Several persons with various grades of microtia are probably depicted in the altarpiece of the "Master of the Wenemaer Triptych" in the Museum for Fine Arts at Ghent. The artist painted all the people's faces with life-like features. Deformed auricles are visible in 9 out of a total of 41 persons of all age groups, among the auricles one microtic ear, which belongs to Jesus as a newborn, which is really unusual (Fig. 68)..Fig. 68.

In another scene of this altarpiece, we see Jesus with a normal left auricle and two angels with left-hand microtia (Fig. 69)..Fig. 69.

Fig. 70 probably shows two shepherds as examples for adults with microtia in this altarpiece. In the shepherd with a flute, the ear remnant is positioned extremely low. The neck is short and broad, the mandible seems underdeveloped, and there is some degree of hypertelorism. The bearded shepherd is painted with a left ear that is positioned low on the face. The pinna and the earlobe are underdeveloped, and adjacent to the deformed lobe, there seems to be a skin tag..Fig. 70.

Albrecht Dürer

Coming to the modalities of treating hearing loss in children, we encounter, of course, more miracles than causative methods. The ancients ascribed the inner tempests of severely hearing impaired children who were also believed to be mute as being the work of demons, by which some mutes were possessed. This woodcut depicts St. Aldedrut (Fig. 72) helping a mute girl fettered to a column, a meaningful symbol of the girl's handicap. As the saint, reading from the Bible, is pointing with her fingers at the mouth of the girl, the demons of disease depart from her mouth, where they inhibited her speech..Fig. 72.

This miniature to the initial 'O' (Fig. 73) of the artist Liberale da Verona shows Christ bending over the standing child, touching the child's right ear and lips with his hands in order that he might again hear and speak..Fig. 73.

In this ex-voto dating to 1720 (Fig. 74), the cure of deafness is represented by two bright rays, which link Saint Mary (cut off in this detail) in the clouds with the ears of the child who lost his hearing after a severe illness, and received help. This ex-voto shows the mother in the foreground who also tries to help her son..Fig. 74.

In the next ex-voto (Fig. 75), a mute boy is standing all alone in the countryside looking up to Saint Mary in the clouds for help. Beneath Mary, we read: "The child is mute, 1816"..Fig. 75.

To facilitate the ability of speaking in infancy, the frenulum was cut, a recommendation since the time of the Roman writer Celsus. The town physician of Ulm, Scultetus, described in his surgical textbook "Armamentarium Chirurgicum" which instruments were used to cut the frenulum off the tongue, namely a small scalpel and a special tongue forceps (Fig. 76). Many had to pay for this operation with their death due to bleeding or infection..Fig. 76.

In Fig. 77, Jules Lenepveu depicts how Jacob Rodrigues Pereire, the first teacher for deaf-mutes in France, tries to teach the girl Marbois from Orléans to recognize tones via the vibrations of the larynx..Fig. 77.

A miniature, with four events in the "Book of the Deeds of our Lord Saint Louis", tells the story of a boy in the 13th century who was deaf and mute by birth. The miracle happened at the grave of St. Louis. We see how the deaf boy is approaching the grave together with other diseased people (Fig. 78, left). On the right part of the figure, the boy is kneeling in front of the grave praying..Fig. 78.

The miracle made the boy able to hear the bells (Fig. 79) and even more miraculously, he realized that he was able to speak, as noted by his lifted arms and his open mouth (Fig. 80).Fig. 79.Fig. 80.

In this presentation, you have seen a lot of miracles that happened due to prayer and the help of saints. In the last 100 years, more and more miracles in handicapped children have been achieved on the base of scientific progress, technical development, and surgical skill. What is the future? Will we still need miracles of the older type at all when all the details of diagnostics and treatments have been explained on a rational base one day? I think so, because healing which we physicians have experienced every day with our patients will not be possible without the help of an omnipotent creator.

Acknowledgements

I am very grateful to Dr. Jörg Lindemann and Dr. Siegfried Tewes for helping to prepare this paper for a Power Point presentation.