The present paper is aimed to ascertain the proper identity of Muladhara Chakra by a meticulous search. Proceeding in that direction, a review of the Muladhara Chakra was carried out in the texts of tantric literature, modern literature, journals and online publications. After going through various literatures, it is found that hindrance in normal body physiology may occur due to deactivation of Shat Chakra. Anatomically, each Chakra represents various plexus and sub-plexuses which are concerned with certain organs and its supply. Hence, there is a need to find each and every anatomical structure related to Chakras. Acharya Gananath Sen in his commentary Pratyaksha Shariram concluded that all the pelvic organs closely resemble with Muladhara Chakra. A cadaveric dissection has been carried out to correlate and establish that the anatomical structures which closely resemble the Muladhara Chakra can be thought of as inferior hypogastric plexus and its sub plexuses.