PHMR is an international team of highly qualified health economists and research scientists

From the outset, health technology companies need to integrate health economics and health outcomes research in their product development strategy to ensure a focus on the market and maximise reimbursement, funding, uptake and market access at launch and beyond.

PHMR is an international team of highly qualified health economists and research scientists that offer expert advice based on extensive experience in HEOR and PR&MA groups in Global, EU and Emerging markets.

PHMR offers HTA and guideline reviews specific to client and product needs with options to focus on specific payers, and HTA bodies. PHMR has extensive experience in producing reviews of HTA submissions in multiple disease areas that have been used by clients to navigate the pricing and reimbursement bodies who ultimately determine market access.

PHMR offers a range of services, including:

• Provision of strategic advice• Evaluation of existing evidence and recommendations on other evidence needed• Information and analysis to support pricing decisions and positioning options• Communication and publications for market preparation and support

Mark Ratcliffe

Mark is the founder of PHMR and has developed the company into a successful health economics, pricing and market access consultancy working with a range of top 10 pharma companies. He has a vast amount of experience in the health economics, pricing, reimbursement and market access fields. He also possesses decades of experience with major international pharmaceutical companies and previous work in senior economics research positions.

Louise Longworth

Louise has 20 years of experience in health economics, health technology assessment and health outcomes and an in-depth knowledge of the methods of HTA. She has advised clients on HTA strategy and evidence generation in a diverse range of clinical areas. Louise has specialist experience in the area of outcome measurement and valuation. She has been a member of the EuroQol Group, the organisation responsible for the development of the EQ-5D instruments, for most of her career and currently holds a position on the Board of Directors.

Jeremy Morgan

Jeremy has extensive experience in leading large national, regional and global commercial operations in major pharmaceutical companies. Jeremy brings a wealth of experience to his role at PHMR, providing strategic advice to our clients on commercialisation at all stages of product development, from initial clinical development, to launch, to late lifecycle. He is an expert in commercial strategy development and operational execution. Most recently he led the launches of multiple new diabetes therapies across Europe, Japan, Canada and Australia including novel proteins and biosimilars.

Cormac Sammon

Cormac is an epidemiologist with several years’ experience of successfully delivering observational research projects for a variety of clients. His work has utilised real world data to contribute across the drug development process from establishing the clinical and economic burden of disease, to informing key parameters of cost-effectiveness models and monitoring the long term post-marketing safety and effectiveness of drugs. He has been published extensively across a range of clinical, therapeutic and methodological areas.

Donna Fountain

Donna has managed and delivered a wide range of projects to help pharmaceutical companies with their health economics and outcomes research needs as well as maximising market access/reimbursement for new pharmaceutical and diagnostic interventions. She has a proven history of successfully leading on client projects and performing effectively at all stages of the project cycle.

Jeshika Singh

Jeshika’s key responsibility at PHMR is outcomes research, including PRO development, use and preference elicitation studies. She is advanced in methods used commonly by instrument developers such as factor analysis, regression analysis, IRT and SEM with a focus on item selection. She has developed an instrument to measure patient experience that is amenable to valuation and could potentially inform economic evaluation of quality of care interventions.

Kevin Cadwell

Kevin is an experienced consultant who has responsibility as a project director managing teams of reviewers in our Newcastle Office. He specialises in systematic literature review methodology and delivers reports to clients that meet international HTA and Cochrane standards. Kevin has completed reviews in clinical efficacy, network meta-analysis, diagnostic accuracy, economic evaluations, health-related quality of life, HTA submissions, guidelines/treatment pathways, and disease epidemiology over a wide range of therapeutic areas.

Matt Glover

Matt is a health economist with extensive experience in conducting economic evaluations of new treatments and specialises in long-term modelling, with knowledge of a variety of software and conceptual models. He has contributed to and advised biopharma clients on submissions to a number of HTA agencies. He has also contributed health economic input to the design of numerous randomised controlled trials and analysed and synthesised trial data.

Megan Besford

Megan has extensive experience working across a variety of stages of the drug development process, ranging from analysis of Phase I and III clinical trial data to conducting systematic literature reviews and network meta-analyses for health technology assessment submissions. Megan is familiar with a wide range of common and novel statistical methods used in the pharmaceutical industry and has experience using both frequentist and Bayesian frameworks. She is also proficient with a wide range of programming languages, including SAS, R and WinBUGs.

Siobhan Bourke

Dr Siobhan Bourke has conducted multiple preference elicitation studies using a range of methodologies. She is experienced in developing surveys for a range of respondents, including general population, clinicians, decision makers and patients. Her principal research interest is the economics of rare disease and valuing preferences for health and social care. She is also experienced in qualitative research to help inform preference surveys. She has a PhD in health economics from Bangor University.

Rebecca Brown

Rebecca has a background in medical writing and horizon scanning for HTA organisations as part of a national horizon scanning centre. She has experience of conducting systematic reviews, from conception to completion, planning and conducting a clinical trial and preparing oral and poster presentations for a variety of audiences. Rebecca has experience in several disease areas including musculoskeletal health, nutrition and gastrointestinal disease.

Gintare Cepinskaite

Gintare’s journey at PHMR began in 2013 when she joined the
company as Administrative Assistant to help establish the Newcastle upon Tyne
(UK) office. Currently she is part of the team providing support to the growth
of the company by keeping HR operations aligned to the company values. Gintare
is passionate about her role and she strongly believes that positive working
relationships are the foundation for any kind of success. In her spare
time Gintare attends art exhibitions, goes on contemporary theatre breaks,
reads world literature and enjoys outdoor trips, especially if foraging is on
the agenda.

Patrick FitzGerald

Dr Patrick FitzGerald has made a career in quantitative analysis, including statistical and probabilistic modelling. He has worked in health economics since 2001 and been involved in many quantitative aspects of the work: probabilistic modelling, complex meta-analysis, statistical analysis to generate model inputs, generation of designs and analysis of discrete choice experiments, and software development.

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Lefteris Floros

Lefteris carries broad knowledge in health economics having served in multiple academic and commercial positions. He holds great experience with the collection, evaluation, and modelling of clinical and cost data having designed numerous clinical trial based economic evaluations and having led the development of multiple economic models for HTA submission purposes. He also carries great familiarity with HTA agency processes having been part of the technical teams supporting expert committees of UK NICE clinical guidelines.

Dave Fox

Dave has considerable experience in the information and library field supporting health research. He is responsible for designing literature searches and strategies to support the wide variety of projects and research that PHMR undertakes and managing the results of searches using reference management software. He has run literature searches to support numerous reviews including NICE single and multiple technology assessments, Cochrane reviews, Public Health Research Council projects, and British Thoracic Society clinical guidelines.

Nicola Illingworth

Nicola has conducted focussed and pragmatic literature reviews and contributed to projects on clinical trial design and burden of illness studies, global HTA strategies and the use of patient reported outcome measures in HTA. Nicola has extensive experience in clinical trial method development and has developed skills in data extraction and data management, presenting reports in the form of slide decks or word documents, as well the preparation of manuscripts and posters.

Persefoni Ioannou

Persefoni has a strong background in the field of medical writing with extensive experience in proofreading, quality assessment of publications and data extractions. Since starting work at PHMR, she has been involved in a range of projects, including preparation of manuscripts, pragmatic literature reviews, early pipeline assessments, global value dossiers and health technology assessment reviews. Persefoni has worked in a range of disease areas, including musculoskeletal diseases, gastrointestinal diseases, mental disorders and haematologic malignancies.

Gabriel Jones

Gabriel has experience in conducting multiple stages of systematic reviews from protocol development through to interpretation and communication of results in written format. He has contributed to reviews across a wide range of therapeutic areas which have been used to support strategic drug development, value message development, economic modelling, and to inform HTA submissions. In addition to systematic reviews, Gabriel has contributed to the development of dossiers and materials for publication and congress activities.

Thomas Leahy

Thomas is a statistician and has been involved in a variety of projects using real-world data to inform decision making and insight. He has worked with a variety of frequentist and Bayesian modelling approaches with complex spatio-temporal data using state-of-the-art MCMC fitting procedures. He is proficient in R and Python.Currently, he is completing his PhD at Imperial College London after having a varied background in mathematics and statistics with applications in various areas. He has presented at conferences and workshops nationally and internationally and is published in peer-reviewed journals.

Helen Lilley

Helen is experienced in conducting systematic and pragmatic literature reviews (clinical and economic), and in developing value messages and global value dossiers. She has worked in the fields of immunology, molecular biology, physiology, and cell biology research. Helen has written and edited a wide range of medical documents, including published manuscripts, posters and oral presentations.

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Darryl Low

Darryl has experience in conducting clinical systematic reviews and preparing manuscripts and slide decks for high impact peer-reviewed academic journals and conferences. He has extensive experience in searching and reviewing primary chemical literature; prior to joining PHMR, he was involved in the pharmaceutical industry as a medicinal chemist. Darryl has managed and contributed to projects in a range of therapeutic areas, including schizophrenia, epilepsy and inflammatory diseases.

Aurelie Meunier

Aurelie joined PHMR after successfully completing an MSc in Health Economics at the University of York. She has experience in decision modelling and developing and adapting models for local HTA agencies. Prior to joining PHMR, she conducted policy evaluative research in academia gaining experience in data analysis using econometrics methods. Additionally, she holds an MSc in Chemical Engineering and has previous work experience in marketing in the pharmaceutical industry.

Rachael Miller

Rachael has been involved with a range of projects at PHMR and has experience conducting multiple stages of systematic reviews and working with meta-analyses. Previous experience in clinical trial management has also allowed her to develop skills in stringent data analysis, leadership and communication with commercial and academic sponsors, as well as clinical trial patients.

Rachel Payne

Rachel has been involved in a range of projects at PHMR, including systematic and pragmatic literature reviews, advisory boards, HTA submissions and the preparation of a wide range of value communication documents. She has experience in the therapeutic areas of IBD, AAV and CKD, and extensive experience in nutraceuticals research prior to joining PHMR. She has prepared manuscripts for publication in high impact peer-reviewed research journals and presented at international conferences.

Robyn Roberts

Robyn joined PHMR in January 2019, as Administrative Assistant, based in the Newcastle office. She has 14 years admin support experience, 13 of those spent with the Royal Society for the Protection of Birds, where she supported the Reserves & Education teams. Robyn is passionate about customer service & admin support, & feels that effective administrative support is key to the successful running of any professional organization. She excited to be part of the Science & Innovation hub in her home town. In her spare time, Robyn is a keen knitter and knitwear designer, and enjoys walking on her beloved Northumberland coast & countryside, & further afield.

Caroline Shaw

Caroline has been involved in conducting systematic and pragmatic literature reviews of clinical efficacy, economic evaluations, health-related quality of life and burden of illness, to support market access strategies. She has experience in all aspects of the review process, including developing protocols, screening, data extraction and report writing. She has also conducted primary market research with payers and KOLs to assess market access opportunities. Before joining PHMR, Caroline worked in academia in public health research, where she performed observational and interventional studies, as well as systematic and scoping reviews.

Elaine Stamp

Elaine is a medical statistician with extensive experience of statistical input into clinical trials and large public health projects. She possesses experience in analysis of trial data using advanced techniques, merging large patient data sets to assess public health interventions and is fully compliant with Good Clinical Practice (GCP) with up to date certification. This includes contributing to study design, protocol development and the writing of Statistical Analysis Plans (SAPs) as well as the analysis of data using a wide variety of statistical techniques.

Catherine Watson

Catherine’s main responsibility at PHMR is focussed on undertaking pragmatic and systematic literature reviews. Prior to joining PHMR, Catherine worked for 15 years in clinical trial management in an academic and commercial trial environment and was involved in Phase II/III trials across different therapeutic areas. She has developed skills in data monitoring, communication with commercial and academic sponsors and preparing/submitting complex study documentation. During her PhD, she prepared manuscripts for publication and has presented at international conferences.