After visiting dozens of hotels as an international pilot for American Airlines for more than 20 years, Mark Wyant developed his dream: The Saint Hotel, which opened its doors in New Orleans’ French Quarter in January.

Louisiana’s only Autograph Collection hotel — a high-end collection of independent (read: not part of a chain) hotels in the Marriott family — the Saint breathed life into the old Audubon Building on Canal Street. The $45 million renovation converted the landmark structure into a 166-room, eight-story boutique hotel complete with luxurious amenities, a live-jazz speakeasy (Burgundy Bar) and a brasserie-style dining room (Sweet Olive) from famed NOLA chef Michael Stoltzfus of Coquette. Rates start at $189 per night, www.thesainthotelneworleans.com