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infused alone or added to opioid solutions, bupivacaine and clonidine can provide pain relief for patients who do not get relief from opioids alone, and they can mini- mize the side effects of the opioids by decreasing the doses needed for pain re- lief.

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if therapy is to be discontinued in patients receiving a beta-blocker and clonidine concurrently, the beta-blocker should be withdrawn several days before the gradual discontinuation of catapres tablets.

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the effect of clonidine on such an explicitly spatial aspect of task performance is mirrored by clonidine-induced attenuation of activity in right superior parietal cortex during spatial orienting, an area which has been heavily implicated in spatial attentional orienting corbetta et al.

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do not take this medicine if you are also taking fluvoxamine or certain medicines for high blood pressure such as clonidine, guanfacine, guanabenz, or methyldopa .