Intrinsically Disordered Proteins

Keynote Speaker:Lila Gierasch, University of Massachusetts, Amherst, Moving the Protein Folding Problem from the Test Tube to the Cell

Keynote Speaker:Peter Wright, Scripps Research Institute, IDP Research in 2013: what have we accomplished and where are we going?

James Bardwell, University of Michigan, Structural Studies on the Activation and Substrate Binding of a Conditionally Disordered Acid-Activated ChaperoneAd Bax, National Institutes of Health, Alpha-Synuclein, An Intrinsically Unstructured Protein.How Interesting Can It Be?Liesbeth Veenhoff, University of Groningen, The Netherlands, A Long Disordered Linker in Nuclear Transport of Membrane ProteinsGaragin Papoian, University of Maryland, Acetylations of Lysines of the H4 Histone Tail lead to Functionally Important Remodeling of its Energy LandscapeJeffrey Hayes, University of Rochester, Linker Histone Structural Transitions upon Binding to DNA, Mononucleosomes, and Oligonucleosomal ArraysJörg Langowski, German Cancer Research Center, Germany, Dynamics of Nucleosome Tails Studied by All-Atom and Course-Grained MD SimulationsElisar Barbar, Oregon State University, Intrinsic Protein Disorder in the Regulation of Large Molecular MachinesJennifer Lee, National Institutes of Health, Membrane Curvature Generation by α-SynucleinBen Schuler, University of Zürich, Switzerland, Probing the Polymeric Properties of Unfolded and Disordered Proteins with Single-Molecule Spectroscopy

Mechanobiology

Linda Kenney, University of Illinois, Chicago, OrganizerDennis Discher, University of Pennsylvania, From Matrix Elasticity to Nuclear Physics in Lineage ProgramsGV Shivashankar, National University of Singapore, Singapore, Nuclear Mechanics and Genome RegulationMike Dustin, New York University, T-cell Receptor-Associated Actin Patches Generated by Wiskott-Aldrich SyndromeAntoine Triller, Institute of Biology at Ecole Normale Superieure (IBENS), France, Synapse Stability and Plasticity: From Super-Resolution to Physical Chemistry of Molecular InteractionsJennifer Zallen, Rockefeller University, Shaping the Embryo: Cellular Dynamics in DevelopmentRob Phillips, California Institute of Technology, Bacteria Are Stressed Out Too: The Physics of Mechanosensation

Bonnie A. Wallace, University of London, United Kingdom, The Open Conformation of a Voltage-Gated Na Channel Reveals the Transmembrane Pathway and Gating MechanismKevin J. Foskett, University of Pennsylvania, Regulatory Proteins of a Mitochondrial Calcium UniporterPeter H. Larsson, University of Miami, Regulation of Voltage Sensor Movement in KCNQ Channels by KCNE Beta Subunits

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