College hockey’s version of March Madness gets underway this afternoon and the 16 teams that are in the tournament, they know that one loss ends their season. How do things shake out in the four regionals? Safe to say we’ve got 12 curious games to get us through the weekend.

Here’s the quick and the dirty on the first round games as well as my idea on how things shake out as the road to Pittsburgh and the Frozen Four sets up.

Northeast Regional – Manchester, NH

1. UMass-Lowell vs. 4. Wisconsin

Lowell took down their first ever Hockey East tournament title while Wisconsin roared through the WCHA to win that conference’s tourney. For a 1-4 game, this one’s a doozy. The Badgers have the tourney history, while the Riverhawks have been rolling since December. Lowell will go as far as freshman goalie Connor Hellebuyck takes them.

Both teams bowed out of their conference tournaments early. Both teams landed extended vacations before the NCAAs. Who does the break help? Who does it hinder? New Hampshire has home ice and Denver didn’t do well in 2010 when they headed east for the tournament. Hmm…

It’s the top seeded team in the tournament against the last seeded team. In the NCAA basketball tourney that usually means the top team wins in a walk. Not so for the hockey tourney. That said, Canisius is on a roll after winning the Atlantic Hockey tournament. Then again, they were not overly good this season. Quinnipiac lost in the semifinals of the ECAC tournament to Brown. This could wind up being the closes of the 1 vs. 4 games in this year.

An intriguing match-up of what could’ve been last year’s national championship game had Union beaten Ferris State in the national semis. BC is the perennial vampire of the playoffs. They’re not done until you put the stake through their heart. Union is on fire having won their way through the ECAC tournament on their way to the title. The Dutchmen are a chic pick to make the Frozen Four out of this region and that’s just what Boston College (with Jerry York back behind the bench) likes to hear.

The Fighting Irish battled their way through to win the final CCHA tournament and earn a No. 1 seed. Lucky for them they get to face the WCHA’s co-regular season champs from St. Cloud State. Some reward. Jeff Jackson’s Fighting Irish played strong throughout the playoffs while St. Cloud disappointed in the Final Five. This one’s an honest to goodness toss-up, but keep in mind that the Huskies did not fare too well out of conference this season (swept by Northern Michigan and New Hampshire, lost to Rensselaer).

The Redhawks have become a fixture in the NCAAs. Unfortunately for them, they have yet to win a national title. They came up short in the CCHA tournament so they’ve got motivation to prove they’re better than that. Minnesota St. is making their first appearance in the NCAAs since 2003 and don’t look for them to take the “glad to be selected” approach. They’re a darkhorse team to come out of this region.

The Golden Gophers were a co-dominant force this season along with Quinnipiac and are the definitive No. 2 team in the tournament. Getting rewarded with a mercurial Yale squad doesn’t make life easy for them. If they run into the Bulldogs team that has goalie Jeff Malcolm stopping everything and them pushing the pace offensively, Minnesota will have their hands full. If they get the Yale team that “showed up” in the ECAC semis and consolation game, it’ll be a walk in the park as they haven’t scored a goal since the ECAC quarterfinals against St. Lawrence.

The formerly Fighting Sioux boast perhaps the best offensive one-two punch in the tournament with Hobey Baker finalist forwards Danny Kristo and Corban Knight. They’ve combined for 99 points this season alone but Niagara boasts a Hobey finalist of their own in junior goalie Carsen Chubak. You can debate the competition he’s faced but his numbers do all the talking (1.91 GAA, .938 SV%). North Dakota is capable of winning it all, but Niagara will look to give them fits.

Prediction: Keep in mind I’m terrible at predictions (but you knew that by now) but I like UMass-Lowell, Boston College, Minnesota St., and North Dakota to make it to Pittsburgh. If I go 0-for-4 on those picks, I won’t be the least bit surprised. There’s no overly dominant team with a gift-like road to the Frozen Four this year.

We’re taking you “Back To Class” for our roundup of the weekend’s action in college hockey. Look for more college hockey on NBCSN Friday, November 16 at 7:30 p.m. ET as Cornell takes on Harvard.

There’s something very wrong with the Maine Black Bears.

Last season, they were an NCAA tournament team with a Hobey Baker finalist in forward Spencer Abbott. While Abbott is gone, fellow big scorer Joey Diamond is back again this season but coach Tim Whitehead’s team is very much in the dumper.

Maine’s problems might be too many to count right now. Junior goalie Dan Sullivan is off to a miserable start and backups junior Martin Ouellette (Columbus) and freshman Matt Morris have been worse. They’re 1/44 on the power play so far this season (2.3%) a rate that’s miserable at any level.

As for Diamond? The good news is he leads the team in scoring. The bad news? He has just one goal and three assists. If Maine doesn’t start fixing things soon, they could wind up missing the Hockey East playoffs, never mind the NCAAs.

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Series of the weekend: Boston University and North Dakota faced off in Grand Forks and made it worthwhile splitting the weekend set. North Dakota took down the Terriers on Friday night 4-2 while BU turned it back around on the formerly Fighting Sioux by the same score on Saturday. Can we see more inter-conference stuff like this, please?

2014 Regionals: If you’re planning way ahead for the 2014 NCAA tournament, you’ll need to book a hotel in either St. Paul, Worcester, Bridgeport, Cincinnati to do it. Interesting seeing the NCAA go back to Cincy after having nightmarish issues there in 1996. Now the committee will hope Miami University can earn a spot to make it their home for the weekend.