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Description

Molecular Approaches to Immunology is the 9th volume of the series ""Miami Winter Symposia"". This volume presents papers that cover various aspects about cellular and modern immunology. Cellular immunology deals with the interactions of cells and molecules of the immune system and how these interactions help eliminate pathogens.The main goal of this book is to discuss and provide basic assumptions, approaches, and direction about the advances in the research of immunological science. In relation to this, the chapters of the book examine the recognition of antigen by T-lymphocytes, the role of cell interactions in determining the immune responsiveness, and the concepts behind clonal selection. The book also explains the different genes coding used for antibodies and the characterization of cell surface receptors at molecular level. Furthermore, it examines the evidences for genetic restrictions in cell interactions and the chemical properties of thymosin used in physiological studies. Discussions on the immunoregulation and immunological tolerance by T cells and the growth control of mammalian cells are also presented in this volume.
This compilation will be invaluable to biologists, medical practitioners, professors, and students.

Table of Contents

Speakers, Chairmen, and Discussants
Preface
The Sixth Feodor Lynen Lecture
The Shock of Molecular Recognition
Introduction
The Subject and Style of Modern Immunology: An Introduction
Current Concepts in Cellular Immunology
Discussion
Recognition of Antigen by T Lymphocytes
Discussion
The Logic of Cell Interactions in Determining Immune Responsiveness
Discussion
The Use of Mutant Myeloma Cells to Explore the Production of Immunoglobulins
Discussion
Immunoglobulin Genes in a Mouse Myeloma and in Mutant Clones
Discussion
Genes Coding for Antibodies
Discussion
The Organization and Diversity of Immunoglobulin κ and γ Genes
Discussion
Cell Surface Antigens and Cell Surface Proteins
Discussion
The Role of Products of the Histocompatibility Gene Complex in Immune Responses
Discussion
The Role of Thymosin and the Endocrine Thymus on the Ontogenesis and Function of T-Cells
Discussion
Immunoregulation by T Cells
Discussion
Control of Growth of Mammalian Cells
Discussion
Restricted Clonal Responses: A Tool in Understanding Antibody Specificity
Discussion
Poster Session: Communications
Repetitive Hinge Region Sequences in a γ3 Heavy Chain Disease Protein-Isolation of an 11,000 Dalton Fragment
Structural Characterization of a Mutant Human Lambda Immunoglobulin Type L-Chain
Heterogeneity of the C-Region of an IgGl Immunoglobulin: The Structure of γ-Heavy Chain Disease Protein Baz
Growth Factor for a Viral Transformed Cell From Rat Liver and Hemicorpus Perfusions
Lymphocyte Responses to Mitogens and Antigens in Agarose-Gel Cultures
Sterol Synthesis in Normal, Phytohemagglutinin-Stimulated, and Leukemic Mouse Lymphocytes
Can Protein Synthesis in Cultured Cells Be Regulated by Membrane- Mediated Events?
Alteration of Membrane Antigens by Trypsin
IgM Complex Receptors on T and B Lymphocytes
B and T Lymphocytes in Dysgammaglobulinemia
The Role of Thymic Extract in Transfer of Delayed Hypersensitivity (D.H.S.) and Immunostimulation
Growth Properties and Alloantigenic Expression of Murine Lymphoblastic Cell Lines Grown in Suspension Culture
Regulation of Ab Activity of Rabbit (Rab) Ig+Lymphocytes (LC) by Products of Rab Ig⁻LC
Evidence for the Genetic Control of Antigenic Modulation
The Response of Congenitally Athymic (NUDE) Mice to Infection with Mycobacterium bovis (Strain BCG)
Nonspecific Stimulators of the Immune System