"I'm not naive enough to think that with 45 Republicans in the Senate, we're going to be successful in repealing and replacing Obamacare," Portman said, "but that's where I stand."

A bit later, he continued, "The likelihood is that given the fact that there are 55 Democrats and 45 Republicans, that we will be unsuccessful in that. And ultimately, of course, the president has issued a veto threat."