Gilles Simon, the 19th seed, also fell as grass-court specialist Feliciano Lopez notched up a 6-2 6-4 7-6 (13-11) victory over the Frenchman.

Milos Raonic and Grigor Dimitrov both enjoyed straight set successes as they progressed, while there were also wins for Kei Nishikori, Kevin Anderson,Jeremy Chardy, Andreas Seppi and Alexandr Dolgopolov.