Fight microcephaly with arigo

Fight microcephaly with arigo

A good model for the study of microcephaly is important. Qian et al. describe a method to generate cerebral organoids by culturing human iPSCs under specific conditions that can self-assemble to form 3D-aggregates of neural cells. Cerebral organoids resemble brain tissue and that can be a good model for human cortical development.

By examining the effects of ZIKV infection on forebrain organoid growth, Qian et al. found that ZIKV infection induced proliferation deficits in NPCs and increased cell death and decreased VZ and neuronal layer thickness (a feature associated with microcephaly).

arigo accelerates study of ZIKV-caused microcephaly by providing excellent antibodies for the study of cortical development.