Cardiovascular Diseases

Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) announced that the license and collaboration agreement between Arrowhead and Amgen covering the novel RNAi ARC-LPA program has closed, following early termination of the waiting period.
About ARC-LPA
ARC-LPA is designed to reduce production of apolipopr more

A strong association between a genetic mutation and a rare kind of heart muscle disease has been discovered by researchers at the University of Colorado Anschutz Medical Campus.
The finding could improve understanding of the disease and lead to new treatments.
"There are many kinds of cardiomyopathi more

Research from the University of Glasgow shows that people who have a cardiometabolic disease, such as high blood pressure, diabetes or coronary heart disease (CHD), perform worse on mental tests of reasoning, memory and reaction time, and having more than one of these conditions has an even greater more

Although congenital heart malformations are the most common birth defects in humans, the underlying patho­mechanisms remain widely unknown. Through linkage analyzes and candidate-gene approaches, several gene mutations causing congenital heart defect more

In all oxygen consuming cells, metabolism and oxidative stress generate several intermediates and byproducts that are collectively known as reactive oxygen species (ROS). ROS are necessary intermediates in the human body, but they are also involved i more

Up until the new millennium, the pharmaceutical industry grew stronger by 11%. However, the blockbuster model is increasingly at risk and the declining growth rates in the industry require a search for new strategies. In this context, orphan drugs ar more

by Yu Zhang, Shiguo Chen, Chaoyang Wei, Hui Gong, Lanqi Li, Xingqian Ye
Oxidative stress is highly associated with the development of cardiovascular diseases and cancer and has drawn great attention. Natural products suggest a potential role in prevention of these disorders. The aim of this study more

Background
Geographic variation in congenital heart disease is not well‐described. This study uses geographic information systems (GIS) to describe the spatial epidemiology of tetralogy of Fallot (TOF), in North Carolina (NC) and to compare travel time for cases to congenital heart centers in NC more

Abstract
Numerous studies have investigated the distribution of methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and their associations with diseases in China. In this study we conducted a systematic review and meta‐analysis of these studies (715 eligible studies in tot more

TechNavio’s analysts forecast the Drug-eluting Stent market in Europe to grow at a CAGR of 4.3 percent over the period 2011–2015. One of the key factors contributing to this market growth is the high prevalence of cardiovascular diseases in the region. The Drug-eluting Stent market in Europe has als more

TechNavio’s analysts forecast the Global Implantable Cardioverter Defibrillator (ICD) market to reach US$6.22 billion by 2015. One of the key factors contributing to this market growth is the rising incidence of Cardiovascular diseases. The Global ICD market has also been witnessing the development more

TechNavio's analysts forecast the Global Bare Metal Stents market to reach US$1.86 billion by 2015. One of the key factors contributing to this market growth is the high prevalence of cardiovascular diseases. The Global Bare Metal Stents market has also been witnessing the trend of increasing demand more