Collagenous colitis with mucosal tears in two proton-pump inhibitors and non-steroidals naïve patients who developed metachronous cancers.

MedLine Citation:

PMID:
23134231
Owner:
NLM
Status:
Publisher

Abstract/OtherAbstract:

Microscopic colitis (MC) is an umbrella term comprising two entities, lymphocytic and collagenous colitis (CC), which is essentially diagnosed by pathology. Minor mucosal edema and/or erythema can sometimes be observed on endoscopy, but these changes are mostly subtle, patchy and rather non-specific. Recently, several reports of proton pump inhibitors (PPIs)- or non-steroidal anti-inflammatory drugs (NSAIDs)-induced CC associated with colonic mucosal defects have been published. In the current study, we presented two patients with CC and colonic mucosal defects unrelated to PPIs and NSAIDs administration.