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Thursday, 27 February 2014

Role of Semen Preparation Techniques in Success of IUI – Where and How?

Dr. Aruna Saxena ,Dr. Sharda Jain, Dr. Jyoti Bhaskar, Dr.Jyoti Agarwal, Dr. Abhishek PariharIntrauterine insemination is accepted as the most common first therapeutic intervention in Infertile couples. It can be performed with or without ovarian stimulation for treatment of cervical factor, mild to moderate male factor, anovulation and unexplained infertility.Big part of the success of IUI lies in semen processing. The semen preparation which is offered as IVF services in Delhi to IVF patients is now universally followed for IUI patients too. It has eliminated the risk of pelvic inflammatory disease and uterine cramping.The aim of semen preparation is to separate the normal sperm from the debris of the ejaculate and in case of IUI, to yield as many normal motile spermatozoa as possible.It is important to remember that for the best results of IUI, Semen preparation should be done in In house Lab and should not be processed outside – as sperm capacitation process starts immediately and inspite of motile sperms, no pregnancy results.We are 30 thousand gynaecologists in India and nearly half of them are practising infertility and doing IUI. It is unfortunate that except in IVFcentres in Delhi Ncr– very few gynaecologists in Delhi have In house lab for semen preparation.

As far as the technique of sperm preparation is concerned – it is clear one size does not fit all.Spermatozoa may be selected by their ability to swim, known as the 'swim-up technique'. This technique is performed by layering culture medium over the liquefied semen. Motile spermatozoa swim up into the culture. The upper part of the layered medium is then carefully removed for further use.

The second method of selecting spermatozoa is by the use of density gradients. The semen sample is pipetted on top of the density column, which is then centrifuged. Density gradient centrifugation separates spermatozoa according to their density. This way we can select the motile, morphologically normal spermatozoa in the solution with the highest concentration of gradient, which is aspirated for further use.

The third method is conventional wash method in combination with centrifugation. The semen sample is diluted with a medium and centrifuged. Subsequently, the pellet (the bottom part after centrifugation) is resuspended in a small amount of medium and incubated until the time of insemination.

It is our experience at Lifecare IVF, a reputed IVF centre in Delhi Ncr, that there is no statistically significant difference between pregnancy rates for swim up versus gradient /wash technique though results from various studies may suggest a preference for gradient technique for most of the samples. Only samples with very good parameters should be prepared by Swim up technique.

Saturday, 15 February 2014

Infertility affects a relatively large number of couples now ranging from 10-15%,

It is evident from news articles that Indian men are facing a queer, unique problem of Both reduced sperm count and suboptimal sperm quality.

Globally , there is a new trend of 'Voluntary Infertility' in girls. Similar trend is found in Indian women, who are educated, independent, career- minded. They defer marriage & childbearing till they can afford all the good things in life.

90 % of women's egg degrade in quality & number at the end of her 37th year. By the time she decides to have a baby, her biological clock, often slows down. She then requires the help of Assisted Reproductive Technique (ART) like IUI, IVF, ICSI to conceive.

With the enormous advances in ART technologies, today, 85 -90 % of the cases of infertility can get pregnant. Lifecare IVF has A to Z of all ART facilities oferreing Total Solution to Infertility. In 2014, we have added PGS / PGD & ERA test for Recurrent IVF Failures.

The Lifecare IVF E- Bulletin will focus on the current trends in Infertility - IUI and IVF - ICSI ,Recent data on the current therapies used, as well as information on additional measures to improve fertility outcome.

The STRESS experienced by the patients undergoing therapy has also been touched upon by us by Counseling by Clinical Psychologist & Acupuncture Expert.

Better outcomes of infertility are likely if the mother gives up smoking and alcohol before undergoing IUI & IVF treatment & normalizes her WEIGHT by our wellness & Health Experts,

IVF Center in Delhi Ncr is in your
service for the last 22 years. We are sure you will continue with your
patronage in the coming year 2014 and for the years to come.

Integrity
and Sincerity of Our Team is the hallmark of our success. Over the years we have realised that the
Indian women are Health Information Hungry. With the aim to provide you
Correct, authenticated information directly from the Horses mouth, we are
launching our monthly E – Bulletin.

Please
do follow us on the Facebook, LifecareCentre/IVF website too for more

According to a recent survey by TOI in August 2013, out of the
world's 100richest people today, 27 are Heirs (Inherited) and 73 are Self
made. These super achievers are not born rich but are self made people. It is not
external favour that makes one a super achiever, but one's own efforts and self
acquired success.

There is a saying that Mr. X was born with a silver spoon in his
mouth. This kind of inheritance creates in the concerned person and kills the motivation.

In
contrast, a child born in a poor family, not sure if he will get the next meal, develops
a kind of discontentment and hunger that kindles a
fire within him to work hard. Living examples
next to you are Mr. Narender Modi, Mr. Kejariwal, Dr.
Walia, Dr. Harshwardhan, Dr. Sharda Jain and Dr. Vinay Agarwal whom you all know.

The
Law of nature is greater and more strict than everything else.

They are Eternal!
They cannot be Changed!

The
Law is - “It is not ease but effort, Not facility
but difficulty – that makes an