Increasing obstructive sleep apnoea (OSA) severity appears to have an independent association with retinal arteriolar narrowing and attenuated vascular pulsation amplitude, with the retinal vasculature a potential surrogate biomarker of cerebral and systemic vascular risk in patients with OSA, according to a study.

New drug applications approved by US FDA as of 1 - 15 August 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.