genetic relatedness

Tag archives for genetic relatedness

An ancestry informative marker set for determining continental origin: validation and extension using human genome diversity panels: Results In this study, genotypes from Human Genome Diversity Panel populations were used to further evaluate a 93 SNP AIM panel, a subset of the 128 AIMS set, for distinguishing continental origins. Using both model-based and relatively model-independent…

In the comments below on the post on human population structure there was some request for a bigger global perspective. Below the fold I’ve placed a table with FST values which compare each population to the other. This an older population genetic statistic derived from the work of Sewall Wright, but you are almost certainly…

I still remember when L. L. Cavalli-Sforza’s The History and Geography of Human Genes was a candle in the dark, illuminating human history with slivers of genetic data laboriously gathered and analyzed over decades. We’ve come a long way. Dienekes points me to a new paper, Fine-scaled human genetic structure revealed by SNP microarrays: We…

Haplotypic Background of a Private Allele at High Frequency in the Americas: Recently, the observation of a high-frequency private allele, the 9-repeat allele at microsatellite D9S1120, in all sampled Native American and Western Beringian populations has been interpreted as evidence that all modern Native Americans descend primarily from a single founding population. However, this inference…

Dan MacArthur has a post, Genetics of complex traits in Europeans and East Asians: similarities and differences: With those goals in mind, you can expect to see many more GWAS of non-European populations over the next couple of years, and some explicit comparisons of the differing genetic architecture of complex traits between populations. Exciting times…

Sheril’s post, Chimpanzees Are NOT Pets!, is good. She notes: 1 Chimpanzees are wild animals. Animals that make good PETS like dogs and cats, have been domesticated for [thousands] of years. There has been selection on them against aggression, which is why a dog, unlike a wolf, will not automatically tear you to pieces. Anyone…