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Harvard Medical School

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Local anesthetics are commonly used in peripheral nerve blockade for the management of postoperative and chronic pain. However, single administrations of conventional local anesthetics often result in nerve blocks that are ...

Neoantigens represent a class of tumor specific antigens that are encoded by somatic mutations which arise in cancer cells. Neoantigens are particularly attractive for the development of personalized cancer vaccines as ...

Osteoporosis is a metabolic bone disorder characterized by depleted bone mass, remodeling of microarchitecture, and an increased incidence of fractures. Predominantly diagnosed through a measurement of low bone mineral ...