Fused Deposition Modeling 3D Printing for (Bio)analytical
Device Fabrication: Procedures,
Materials, and ApplicationsGert IJ. SalentijnPieter E. OomenMaciej GrajewskiElisabeth Verpoorte10.1021/acs.analchem.7b00828.s001https://acs.figshare.com/articles/Fused_Deposition_Modeling_3D_Printing_for_Bio_analytical_Device_Fabrication_Procedures_Materials_and_Applications/5119750In
this work, the use of fused deposition modeling (FDM) in a (bio)­analytical/lab-on-a-chip
research laboratory is described. First, the specifications of this
3D printing method that are important for the fabrication of (micro)­devices
were characterized for a benchtop FDM 3D printer. These include resolution,
surface roughness, leakage, transparency, material deformation, and
the possibilities for integration of other materials. Next, the autofluorescence,
solvent compatibility, and biocompatibility of 12 representative FDM
materials were tested and evaluated. Finally, we demonstrate the feasibility
of FDM in a number of important applications. In particular, we consider
the fabrication of fluidic channels, masters for polymer replication,
and tools for the production of paper microfluidic devices. This work
thus provides a guideline for (i) the use of FDM technology by addressing
its possibilities and current limitations, (ii) material selection
for FDM, based on solvent compatibility and biocompatibility, and
(iii) application of FDM technology to (bio)­analytical research by
demonstrating a broad range of illustrative examples.2017-06-19 18:00:36benchtop FDM 3 D printer12 representative FDM materials3 D printing methodpaper microfluidic devicesFused Deposition Modeling 3 D PrintingFDM technology