Lowering High Lipoprotein(a) Could Lead to Reductions in Cardiovascular Disease

Lipoprotein(a) or Lp(a) is an unusual
form of cholesterol that is highly heritable and runs in families.

Lowering High Lipoprotein(a) Could Lead to Reductions in Cardiovascular Disease

A team of researchers from the Research Institute of the McGill
University Health Center (RI-MUHC) found that elevations in Lp(a) is responsible for one
in 14 heart attacks and one in seven cases of aortic valve disease.

‘Elevations in an unusual form of cholesterol, called Lipoprotein(a) or Lp(a), is responsible for one in 14 heart attacks and one in seven cases of aortic valve disease.’

This form
of cholesterol is not commonly screened for in Canada, so most people
do not even know they are at risk. Although no specific treatments exist
to lower Lp(a), new therapies are being developed, and in addition to
this study, the researchers hope to demonstrate how lowering this form
of cholesterol could have an important impact on the
population.

"Approximately 20% of individuals have high Lp (a),"
says Dr. George Thanassoulis, who is a researcher at the RI-MUHC and
principal author of the study "We hope that our work will raise
awareness that individuals with high Lp(a) are at high risk of heart
disease and hopefully stimulate the development and testing of new
therapies."

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