Dunn has two homers, five RBIs for White Sox

Chris Sale (2-1) struck out 11 in 6 1-3 innings. He gave up three runs and seven hits for the White Sox.

Dunn connected for a three-run homer off Hector Noesi (1-2) in the second inning to make it 6-0. He hit his third home run of the season in the eighth, giving him 31 multihomer games and the first since joining the White Sox last season, when he hit just 11 home runs. It was the first time Dunn had homered against Seattle in 12 career games.

Noesi lasted just 1 1-3 innings. He gave up six hits and six runs to send his ERA soaring to 9.49 from 5.73. Erasmo Ramirez pitched one-hit ball for 3 2-3 innings.

Noesi threw 38 pitches in the first, including an 11-pitch walk to A.J. Pierzynski. Alejandro De Aza singled, Brent Morel walked and Dunn had an RBI double. Alex Rios' sacrifice fly made it 2-0.

Jesus Montero hit his second home run of the season to center field in the sixth and Ichiro Suzuki singled home Brendan Ryan in the seventh to make it 6-3.

Seattle threatened from the start with back-to-back singles by Chone Figgins and Dustin Ackley, putting runners on first and third with none out. But Sale struck out Suzuki and got Justin Smoak to ground into a double play.

The Mariners also put runners on second and third in the second inning, but could not score. They finally broke through in the third when Suzuki had a run-scoring double into the left field corner.

Mariners reliever Hisashi Iwakuma made his major league debut in the sixth inning. Iwakuma was the last player on an opening-day roster that wasn't injured or sent to the minors to appear in a game this season. He pitched four innings and allowed just one run.

Casper Wells doubled twice for the Mariners which were 1 for 13 with runners in scoring position.

NOTES: Former Mariner Ruppert Jones, the first player selected in the 1976 expansion draft, threw out the ceremonial first pitch Friday. . Since 2003, White Sox pitchers lead the majors with 801 quality starts. . The White Sox struck out 16 times Thursday, their most since Sept. 17, 2005, at Minnesota, when they struck out 16 times, too.