After five (or six) years of vanilla-wedded bliss, ordinary suburbanites John and Jane Smith (Pitt and Jolie) are stuck in a rut the size of the Grand Canyon?until the truth comes out! Unbeknownst to each other, they are both coolly lethal, highly paid assassins working for rival organizations.

Yuri Orlov is a globetrotting arms dealer. Through some of the deadliest war zones, Yuri struggles to stay one step ahead of a relentless Interpol agent, his business rivals, even some of his customers who include many of the world's most notorious dictators.