An online web server enabling users perform A-to-Z functional analyses, starting from next-generation sequencing expression data to the identification of important regulators with crucial roles in the investigated libraries. Users can analyze their own experiments or utilize the extensive mirExTra NGS expression library, in order to assess the role of microRNAs and transcription factors in various states, diseases and conditions. DIANA-mirExTra v2.0 permits complete substitution of in silico predictions with experimentally supported interactions and TSS positions for human and mouse. Importantly, the new web server performs sophisticated methodologies and advanced visualizations from a user-friendly interface. The multifaceted modular structure of this web application permits numerous different use-case scenarios and enables researchers to utilize DIANA-mirExTra v2.0 as a one stop shop for differential expression, functional or investigative analyses.

Type:

Web

DIANA-mirExTra specifications

Unique identifier:

OMICS_05978

Restrictions to use:

None

Programming languages:

Javascript, PHP

Computer skills:

Basic

Stability:

Stable

Interface:

Web user interface

Input data:

A miRNA/RNA-Seq read count data sets that can be uploaded for analysis. Users can combine their data with 350 small-RNA-seq and 65 RNA-seq in-house analyzed libraries which are provided by DIANA-mirExTra v2.0.

Database management system:

PostgreSQL

Version:

2.0

Maintained:

Yes

Animals

Homo sapiens

Mus musculus

DIANA-mirExTra support

Maintainer

Ioannis S. Vlachos
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forum

&times

Communicate with other users

Participate in the forum to get support for using tools. Ask questions about technical specifications.