Zebeta

DRUG DESCRIPTION

Zebeta (bisoprolol fumarate) is a synthetic, beta1-selective (cardioselective)
adrenoceptor blocking agent. The chemical name for bisoprolol fumarate is (±)-1-[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]-3[(1-methylethyl)amino]-2-propanol(E)-2-butenedioate
(2:1) (salt). It possesses an asymmetric carbon atom in its structure and is
provided as a racemic mixture. The S(-) enantiomer is responsible for most of
the beta-blocking activity. Its empirical formula is (C18H31NO4)2•C4H4O4
and its structure is:

Bisoprolol fumarate has a molecular weight of 766.97. It is a white crystalline
powder which is approximately equally hydrophilic and lipophilic, and is readily
soluble in water, methanol, ethanol, and chloroform.

Zebeta (bisoprolol fumarate) is available as 5 and 10 mg tablets for oral administration.

What are the precautions when taking bisoprolol fumarate (Zebeta)?

Before taking bisoprolol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain types of heart rhythm problems (such as a slow heartbeat, second- or third-degree atrioventricular block), severe heart failure.