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Elizabeth Lavenza was a young woman in the early 19th century. She was engaged to Victor Frankenstein, a young student of medicine from a wealthy family. Lavenza was in good terms with Frankenstein's father Alphonse and with his younger brother William Frankenstein. Victor left Geneva to study at the University of Ingolstadt, with Lavenza and the Frankensteins waiting in Geneva. During his absence, Victor created a monster and lost control over him. The monster, out of spite, travelled to Geneva and murdered William; meanwhile, Victor's quest to find the monster had taken toll on his health and he was suffering from a fever. At that point, Victor's friend Henry Clerval was taking care of him. Lavenza, who knew and trusted Clerval, wrote him a letter so that Clerval could know of William's death. She also reported that Alphonse Frankenstein's protégée Justine Moritz had been found guilty of the crime and sentenced to death. Victor returned to Geneva and met with his father and with Lavenza; Victor then discovered that his monster was the real murderer, but he could not use this information to save Moritz.[1]

Victor Frankenstein left his family home to go after the monster.[1] Eventually, the monster threatened Frankenstein and forced him to create a mate for the monster. Frankenstein did so, but he then destroyed the female. The monster, in reprisal, killed Clerval and allowed Frankenstein to be arrested for that.[2] Frankenstein was cleared from this charge, but the monster appeared again and promised to be with Frankenstein during his wedding night. Frankenstein returned to Castle Frankenstein and joined his father and Lavenza. Lavenza's presence was a balm for the Frankensteins, as Alphonse Frankenstein noticed Victor to be happier than he had ever been in years.[3]

However, afraid of the monster, Victor Frankenstein tried to escape for his wedding night. After marrying in Geneva a few days later, he left for a secluded island to spend the wedding night. Even then, Frankenstein was so worried that the new Mrs. Frankenstein noticed it and called his attention to that. Frankenstein, appealing to a concern about the security, checked the building with a gun and a candle, looking for the monster…and leaving his wife alone. The monster was spying through her window and remained there for a while, entranced by her beauty and innocence. For a moment, the monster considered not killing her, as it would make him the beast he had once tried not to become.[3]

But the monster changed his mind and crashed into the room through the window. Seeing such a horrible creature, Mrs. Frankenstein tried to scream for help. The monster stopped her by grabbing her with one hand and clasping the other over her mouth. He then killed her, probably by strangulation—however, the monster would later admit that he could not remember that specific moment after attacking Mrs. Frankenstein.[3]

The discovery of his wife's body was a shock to Victor Frankenstein. The news of this new tragedy in his family were so devastating to Alphonse Frankenstein, that he lost his will to live and died soon thereafter. Victor Frankenstein started an active quest to destroy his creature. The doctor died before he could see the monster's death, but news of Victor's decease prompted the monster to attempt suicide. He failed, and survived for many decades.[3] However, the deaths caused by the monster did not end the Frankenstein line, as a number of relatives still survived.[4]