NCK1 is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS.Synonyms: SH2/SH3 adaptor protein NCK-alpha, NCK adaptor protein 1, Nck-1, Cytoplasmic protein NCK1, NCK1, NCK