The varied etiology of appendicitis and the present somewhat chaotic conception of it renders any unique case interesting, and constitutes a reason for the publication of the following cases:

Case 1.—On June 9, 1897, I was called at 6 P.M. to see Mrs. W., 57 years of age, a large fleshy woman, who that morning was seized with colicky pains in the abdomen. Her temperature was 99 degrees F., pulse 96. The abdomen was generally tender, without any localization of pain. She had arteriosclerosis and complained of a cardiac irregularity which had troubled her for some years; otherwise personal and family history were good.June 10, temperature 100 degrees F.; pulse 104; pain more localized in right iliac region; bowels loose, having been moved by citrate of magnesium.June 11, temperature 101 degrees F.; pulse 108; localized tenderness in right iliac region. A sense of resistance over an area