Mailing Address

Dr. Kyriakos A. Kirou, Assistant Attending Physician at Hospital for Special Surgery, is a physician-scientist in the field of academic rheumatology. He has a special interest in the research and treatment of systemic autoimmune rheumatic diseases, such as systemic lupus erythematosus.

Affiliations

American College of Rheumatology, FellowAmerican College of Physicians, FellowArthritis Foundation Member, MemberHellenic Medical Society of New York, MemberNew York Rheumatism Association, MemberNational Psoriasis Foundation, Member

Insurances Accepted

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One of the goals of Hospital for Special Surgery (HSS) is to advance the science of orthopedic surgery, rheumatology, and related disciplines for the benefit of patients. Physicians at HSS may collaborate with outside companies for education, research and medical advances. HSS supports this collaboration in order to foster medical breakthroughs; however HSS also believes that these collaborations must be disclosed.

As part of the disclosure process, this website lists physician collaborations with outside companies if payments were received during the prior year, or if the HSS physician currently receives payment. The disclosures are provided by information provided by the physician and other sources and are updated regularly. Further information may be available on individual company websites.

As of April 21, 2015, Dr. Kirou reported no financial interest relationships with healthcare industry.

By disclosing the collaborations of HSS physicians with industry on this website, HSS and its physicians make this information available to their patients and the public, thus creating a transparent environment for those who are interested in this information. Further, HSS’ Conflicts of Interest Policy does not permit physicians to collect royalties on products developed by him/her that are used on patients at HSS.

Education

MD, Aristotle University of Thessaloniki, GreeceDSc, National University of Athens, Greece

Research Description

Dr. Kyriakos Kirou has been very active in the translational and clinical research of systemic lupus erythematosus (SLE). Our approach has been the close comparison of carefully collected clinical with gene expression data from patients. In particular, we have investigated the role of type I IFN in the pathogenesis of lupus, but also in scleroderma (systemic sclerosis). We have found that the activation of the type I IFN pathway in SLE is independently associated with the presence in the blood of autoantibodies against RNA-binding proteins (RBP), renal disease, serologic activity of the disease, disease-related damage and failure to treat with antimalarial medications. Similar findings were noted in scleroderma. We are currently investigating other candidate biomarkers for lupus disease activity and damage.