Methylscopolamine Hydrobromide
H2O Solubility

Methylscopolamine Hydrobromide
State

Methylscopolamine Hydrobromide
LogP

Methylscopolamine Hydrobromide
Dosage Forms

Methylscopolamine Hydrobromide
Indication

Used as adjunctive therapy for the treatment of peptic ulcer. Also used to treat nausea and vomiting due to motion sickness.

Methylscopolamine Hydrobromide
Pharmacology

Methscopolamine bromide is a muscarinic antagonist structurally similar to the neurotransmitter acetylcholine and acts by blocking the muscarinic acetylcholine receptors and is thus classified as an anticholinergic. Methscopolamine bromide has many uses including the prevention of motion sickness. It is not clear how methscopolamine bromide prevents nausea and vomiting due to motion sickness. The vestibular part of the ear is very important for balance. When a person becomes disoriented due to motion, the vestibule sends a signal through nerves to the vomiting center in the brain, and vomiting occurs. Acetylcholine is a chemical that nerves use to transmit messages to each other. It is believe that methscopolamine bromide prevents communication between the nerves of the vestibule and the vomiting center in the brain by blocking the action of acetylcholine. Methscopolamine bromide also may work directly on the vomiting center. Methscopolamine bromide must be taken before the onset of motion sickness to be effective.