Is Quadrivalent HPV Vaccine During Pregnancy Safe?

HealthDay News — Exposure to the quadrivalent human papillomavirus (HPV) vaccine during pregnancy is not associated with adverse pregnancy outcomes, according to a study published in the March 30 issue of the New England Journal of Medicine.

Nikolai M. Scheller, MD, from Statens Serum Institut in Copenhagen, Denmark, and colleagues linked information on vaccination, adverse pregnancy outcomes, and potential confounders in a cohort of women in Denmark with a pregnancy that ended between October 1, 2006, and November 30, 2013. The authors propensity-score matched women who had vaccine exposure during the prespecified time windows with women who did not have vaccine exposure in a 1:4 ratio.