We always travel with cloth but I think I'm pretty hardcore (though it's super easy so I don't see why not). You just need a wet bag to put the dirty diapers in- for a weekend you'd want a big one and bring a bunch of diapers(; the more the better, especially if you are driving and have room. Bring wipes and spritz or whatever solution you're using and some cream and you're good to go. You could also do liners or disposable inserts.