Despite widespread public attention to distracted and illegal drug-impaired driving in recent years, alcohol-impaired driving remains the deadliest and costliest danger on U.S. roads today. One person dies in an alcohol-impaired driving crash every 49 minutes. The causes of alcohol-impaired driving are complex and multifaceted, but these deaths are entirely preventable. This report offers a blueprint for solving the problem by identifying numerous evidence-based and promising policies, programs, and systems changes to accelerate national progress in reducing alcohol-impaired driving fatalities.