I just finished binging Altered Carbon and I once again noted the absolute hatred of the oligarchy present in modern writing. It is clear to me, more than ever, that Iron Man's enemies need to be richer than he is. It shouldn't even be competitive.

Even though Roxxon started as a private joke from Steve Englehart about Exxon, it has become the nearly unbeatable Marvel antagonist : too huge, too important to ever really fall.

It is possible to beat one of their executives or even one of the shareholders (such as Aleksander Lukin) but Roxxon remains.

The only other corporation with as much power as Roxxon might be Alchemax but only in the near future (2099).

Even in the MCU, its presence made itself felt in the 3 Iron Man movies. Interestingly enough, each time, it was during one of the battles against the main opponent (Obadiah Stane, Ivan Vanko, Aldrich Killian).