Lengthy, detailed, filled with links and riviting - this article interviewing Michael Eisen, co-founder of the Public Library of Science.

And here is a bit with which I am in total agreement: "the time has come for the research community to abandon pre-publication peer review in favour of something more like the 'endorsement' model pioneered by ArXiv. Essentially, he explained, this would mean, 'replacing the ‘filter first, then publish’ by ‘publish first, then filter’. The entire web works that way, and the exceptionalism of scientific publishing is no longer plausible, in my view.' Were the research community to take this step, he added, it could hope to save 'in the order of $3 billion a year'."