Yes those granules will work. However they are not very economic. Fires Ants are actually very easy to control or kill. Therefore it isn't a matter of what works, But rather what method works and costs less to control Fire Ants.

Your cost of Talstar PL Granules is $ 26 for 25 lbs which LOW label rates says it cover just under 11K at a cost of $ 2.36 plus tax per thousand sq ft. My Chemical cost to treat the same 11K area is $ 1.62 instead of $ 26.00. Who do you think can competitively bid Fire Ant Control and turn a Profit.

Thanks for the info Ric. I was going to treat just the fire ant mounds for now, I'm new to the pesticide world.