I've been back to endo last week and though my tsh has come down slightly - 3.6 ( was previously 22 then 19) , he's still aiming to get it suppressed ( thyroid cancer 12 years ago) The best I've felt over those years seemed to be when tsh was almost undetectable.

As a result he's told me to double the thyroxine to 100 ( from 50) and lower the T3 to 10 MCG (split in 2_doses of 5 )

It's now been four days and I'm feeling worse than ever, headaches dizziness and acheing painful body, - generally exhausted and feeling quite desperate .

Is this a normal reaction as I've doubled the T4 ?

I'm wondering ( desperately hoping) that it's a reaction to going up quite a large amount?

Other results were FT4 9.8 and FT3 4.4

He wants to see me and repeat bloods in a month but really don't know how I'm going to carry on til then at this rate.

Amanda, it usually takes 7-8 days for the extra dose to be absorbed and having reduced T3 to 10mcg you're probably running on empty. It won't hurt to take 20mcg T3 for a couple of days, reduce to15mcg for a couple of days and then to the 10mcg your endo recommended as the extra 50mcg T4 kicks in.