"I don't think anything's going to be Lost," he said. "On the other hand, you know, things can take off. I've seen things that I didn't think deserved the attention they got, get it. And the other way around."

O'Quinn - who will next be seen in new ABC drama 666 Park Avenue - admitted that the success of Lost made it difficult to pick his next project.

"It made it very challenging for whatever I was going to do next," he explained. "It would be putting too much of a burden on 666 or anything to have those kinds of expectations. So, I don't have expectations at all. Be prepared for the worst and hope for the best."