How do environments talk to genes?

News

Published: 10Jan2013

A report elucidates the widely recognized, but poorly understood, concept of gene-environment interaction, finding a molecular mechanism in the case of post-traumatic stress disorder: demethylation of a glucocorticoid response element in the stress response regulator FKBP5 that depends on both the risk allele and childhood trauma. [Review on epigenetics and childhood trauma by McGill's Moshe Szyf.]