As you walk through halls of the building in the opening sequence, you briefly see Doug from The Walking Dead Episode 1carrying something in a door. You are to save him or reporter Carley from zombies. Carley usually gets saved. That explains why Doug gets a cameo.

Bandit from The Walking Dead: Episode 2, who shot a bandit for stealing food and later, while destracted by Lee, gets shot by Lily in The Walking Dead: Episode 3, is seen in the opening sequence where you meet Brock Sampson from Venture Brothers. The bandit to whom Brock says, "Good game- see you next week" is Bandit from The Walking Dead: Episode 2.