The Virginia Cavaliers will be looking to pick up a win and cover the spread when they take on the Cardinals in Louisville at Papa John's Cardinal Stadium on Saturday in Week 11 action.

Opening Odds & Computer Pick

The Louisville Cardinals are a 14-point home favorite as of Friday. The total opened at 49, but dropped a point to 48.

Odds Shark computer score prediction models pick a possible 35-17 win for the Cardinals on Saturday. View the computer score prediction and who will win the pick on the moneyline for all upcoming NCAAF matchups here.

Team Betting Records & Power Rankings

Louisville battles the Virginia Cavaliers, currently with a 3-6 mark (5-4 ATS). The over under records, important for totals betting, are 4-5 for the Cardinals and 4-4-1 for the Virginia Cavaliers. Stay Informed: follow us on Twitter for odds specials, betting line moves and Louisville vs Virginia injuries news.

This game matches up the No. 62 (Louisville Cardinals) and the No. 86 (Virginia Cavaliers) teams in the league, according to our current NCAA football Power Rankings at Odds Shark.

Statistical Matchup

Offensively, the game matches up the Louisville Cardinals No. 88-ranked offense (26.22 PPG) against a Virginia Cavaliers defense that ranks No. 97 at 32.33 PPG. The Louisville Cardinals passing attack has averaged 252.22 yards per game, less than the Virginia Cavaliers give up through the air (253 YPG on average).

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