Kanto was the first region introduced in the Pokémon series, being introduced as the setting of the Generation I titles Pokémon Red, Blue, Green, and Yellow Versions, and their Generation III remakes Pokémon FireRed and LeafGreen Versions.

Kanto is connected to Johto, and is located to its east. As such, Kanto can be reached in Generation II's Pokémon Gold, Silver, and Crystal Versions and their Generation IV remakes.