(Natural News) In an article in People.com, Dr. Howard A. Riina, Professor of Neurology at NYU Langone Medical Center said that a brain aneurysm feels like the“worst headache of someone’s life”. Even those with a history of migraines or headaches have described the sensation as feeling like a lightning strike. “It’s this severe, severe headache...

Authors: Nehra V, Rizza SA, Temesgen Z
Abstract
The fixed-dose combination of glecaprevir (GLE), a nonstructural protein 3/4A (NS3/4A) protease inhibitor, and pibrentasvir (PIB), an NS5A inhibitor, was recently approved for the treatment of adult patients with chronic hepatitis C virus (HCV) genotypes 1-6 (GT-1-6) without cirrhosis or with compensated cirrhosis, and for the treatment of HCV GT-1 patients who have failed treatment with either NS5A inhibitors or NS3/4A protease inhibitors, but not both. This combination, administered over 8 or 12 weeks, has resulted in high cure rates in all six HCV genotypes, includ...

ElectroCore said yesterday it inked a collaborative research deal with Massachusetts General Hospital exploring the use of ElectroCore’s non-invasive vagus nerve stimulation tech in targeted treatments for neuroinflammation.
The Basking Ridge, N.J.-based company said that investigators will examine the effects the nVNS system has on neuroinflammatory mechanisms associated with conditions in the central nervous system including pain, trauma and neurodegeneration.
ElectroCore said it will supply up to $1 million through a research grant over four years to support preclinical trials of the device, including work al...

CONCLUSION: the history we report, therefore, confirms previous experiences reporting a possible favourable outcome of pregnancy in patients affected by acromegaly and add further information about the behaviour of giant pituitary tumors in patients underwent pregnancy.
PMID: 30088454 [PubMed - as supplied by publisher]

Abstract
The relationship of sleep and migraine is unequivocal and familiarity with the nature and magnitude of these associations may inform clinical practice. Recent prospective, longitudinal, and time-series analysis has begun to unravel the magnitude and temporal patterns of sleep and migraine. Prospective evidence has shown that sleep variables can trigger acute migraine, precede and predict new onset headache by several years, and indeed, sleep disturbance and snoring are risk factors for chronification. The presence of a sleep disorder is associated with more frequent and severe migraine and portends a poor...

Sometimes, it is fairly safe to assume that a patient is more likely to have a familial disorder than a sporadic form of the same disease. A 39-year-old man was brought to the emergency department by ambulance with chest pain and palpitations. He had a history of migraines and dyspepsia. His family history was remarkable for a sister with Wolff-Parkinson-White syndrome, detected at age 18 years during pregnancy, and a brother with Wolff-Parkinson-White syndrome. The patient's son, born prematurely, was diagnosed with Wolff-Parkinson-White syndrome at 1 month of age, and he underwent ablation therapy when he was 8 years old.

AbstractMany central nervous system diseases currently lack effective treatment and are often associated with defects in microvascular function, including a failure to match the energy supplied by the blood to the energy used on neuronal computation, or a breakdown of the blood–brain barrier. Pericytes, an u nder-studied cell type located on capillaries, are of crucial importance in regulating diverse microvascular functions, such as angiogenesis, the blood–brain barrier, capillary blood flow and the movement of immune cells into the brain. They also form part of the “glial” scar isolating dam...