Gene Family: CST complex

: The CST complex localizes specifically to single-stranded telomeric DNA, including the telomeric overhang. In yeast this complex is involved in chromosome end capping and telomere length regulation. The capping properties of CST may be dispensable in vertebrates in vivo due to the presence of the shelterin complex, which also caps chromosome ends.
There is evidence to suggest that the CST complex rescues stalled replication forks under conditions of replication stress.
[Source: Rice et al]