Menai Science Park Ltd was given planning permission for the project, which will be based near Gaerwen on Anglesey, in July.

Economy Secretary Ken Skates broke the ground to mark the start of work, with the park expected to open by 2017-18.

The project has secured £10.8m investment from the Welsh Government and £10.2m of EU funding.

The aim of the park - owned by Bangor University - is to provide office and laboratory facilities for people who want to grow their business in the region.

Anthony Dillon, managing director of Willmott Dixon Construction Ltd, said the M-SParc building would house up to 300 people.

"In addition we will be providing community benefits during the construction, including internships, apprenticeships, and workshops for local supply chain and people who want to develop their skills in the industry," he said.

Executive director Ieuan Wyn Jones said work had already been ongoing behind the scenes to secure tenants.

Ken Skates said: "Once up and running the science park will offer huge benefits to the North Wales region.

"I am confident that its focus on low carbon and renewable energy sectors will complement the work being undertaken by the Energy Island Initiative and the Anglesey Enterprise Zone and will help local businesses more widely to create jobs and achieve sustainable economic growth."