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The Developmental Care Program centers on finding ways to accurately assess and effectively treat stress and pain responses in preterm infants in the Neonatal Intensive Care Unit. We are conducting a comprehensive program of research that includes studies which are descriptive, mechanistic and interventionist; outcome measures ranging from cellular to behavioural levels; and mothers, fathers and infants born from the earliest gestational ages to term.

Oral glucose during targeted neonatal echocardiography: is it useful?Lavoie PM and Stritzke A and Ting J and Jabr M and Jain A and Kwan E and Chakkarapani E and Brooks P and Brant R and McNamara PJ and Holsti LDOI: 10.1136/archdischild-2015-308191PubMed: 2605497107/2015

Neonatal pain and developmental outcomes in children born preterm: a systematic review.Valeri BO and Holsti L and Linhares MBDOI: 10.1097/AJP.0000000000000114PubMed: 2486685304/2015

The development of the Pediatric Motivation Scale for rehabilitation.Tatla SK and Jarus T and Virji-Babul N and Holsti LDOI: 10.1177/0008417414556884PubMed: 2628143304/2015

A Randomized Controlled Trial of the Use of Oral Glucose with or without Gentle Facilitated Tucking of Infants during Neonatal Echocardiography.Lavoie PM and Stritzke A and Ting J and Jabr M and Jain A and Kwan E and Chakkarapani E and Brooks P and Brant R and McNamara PJ and Holsti LDOI: 10.1371/journal.pone.0141015PubMed: 264963612015

The effects of motivating interventions on rehabilitation outcomes in children and youth with acquired brain injuries: a systematic review.Tatla SK and Sauve K and Jarus T and Virji-Babul N and Holsti LDOI: 10.3109/02699052.2014.890747PubMed: 246610002014

Evidence for outcomes of motivational rehabilitation interventions for children and adolescents with cerebral palsy: an American Academy for Cerebral Palsy and Developmental Medicine systematic review.Tatla SK and Sauve K and Virji-Babul N and Holsti L and Butler C and Van Der Loos HFDOI: 10.1111/dmcn.12147PubMed: 2355089607/2013

Content validation of the infant malnutrition and feeding checklist for congenital heart disease: a tool to identify risk of malnutrition and feeding difficulties in infants with congenital heart disease.St Pierre A and Khattra P and Johnson M and Cender L and Manzano S and Holsti LDOI: 10.1016/j.pedn.2009.04.009PubMed: 2081655910/2010

Is it painful or not? Discriminant validity of the Behavioral Indicators of Infant Pain (BIIP) scale.Holsti L and Grunau RE and Oberlander TF and Osiovich HDOI: 10.1097/AJP.0b013e318158c5e5PubMed: 1818064101/2008

Congratulations to the CFRI investigators who were recently appointed or renewed as Canada Research Chairs. The Canada Research Chair program helps attract and retain top researchers across the country. Eleven CFRI investigators now hold these prestigious appointments.

Dr. Bahaa Abu Raya has been awarded a Vanier Canada Graduate Scholarship (CGS) for his research into whooping cough immunization in pregnancy that helped change Canada’s national immunization guidelines on when expectant mothers should get a booster shot.

On March 11, 2019, BC Children’s Hospital Research Institute hosted the Canadian Institutes of Health Research for the announcement of $1.7-million in funding for early career investigators conducting high impact research in maternal, reproductive, child and youth health.

Donate to Research

We believe there’s nothing we can’t do with your support. It can take years to turn scientific breakthrough into new interventions and treatments. Funding helps speed the pace of change. When given the resources, we can bring transformative therapies – and hope – out of the laboratory and into the clinic to save and improve children’s lives.