This Rapper Just Won The ALS Ice Bucket Challenge With Marijuana

Just when you thought all variations on the Ice Bucket Challenge had been exhausted, rapper B-Real from Cypress Hill shows up with a bucket of marijuana.

"I know we're going through a drought with water and all that stuff, so we're going to do it a little different, but I accept the challenge," B-Real, a noted marijuana advocate, says in a video posted last week to Hustla Subs, a hip-hop YouTube channel, just before a large bucket of marijuana buds is dumped over his head.

"Snoop Dogg, Willie Nelson, Woody Harrelson -- you've got 24 hours to accept," B-Real says at the end of the video, challenging three other celebrities with well-known affinities for cannabis.

We eagerly await responses from these three.

Donations inspired by the ubiquitous Ice Bucket Challenge -- in which participants pour a bucket of ice water on their heads to raise awareness of amyotrophic lateral sclerosis (ALS), a degenerative nerve disease -- have been coming in at an astounding rate since the practice went viral earlier this summer.

As of Tuesday, the ALS Association (ALSA) -- which fights the disease by funding research, supporting people with the condition and corralling federal resources -- had collected $88.5 million toward its efforts, a majority of which had been donated in the past seven days. It's a particularly stunning figure considering that the organization took in just $2.6 million in the same period last year, according to a statement released by the group.

And while B-Real is having some fun with the viral video craze, substituting marijuana for ice water, research suggests that the plant may in fact be an effective treatment for ALS. A study published earlier this year in the journal CNS Neuroscience and Therapeutics found that Sativex, a drug developed by GW Pharmaceuticals that contains both cannabidiol (a non-psychoactive compound found in marijuana) and THC (the main psychoactive ingredient in marijuana that causes the "high" sensation), may slow the progression of ALS symptoms in mice.

There is no known cure for ALS, a condition that affects the nerves and muscles of approximately 30,000 Americans at any given time, according to ALSA. More than 5,000 new cases are diagnosed in the U.S. annually.

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Top 50 Most Influential Marijuana Users

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“It makes me feel the way I need to feel.”

"I have used cannabis all over the world."

“I went to Vietnam, and I was there for a long time. [Using marijuana] made the difference between staying human or, as Michael Douglas said, becoming a beast.”

"Kush rolled, glass full... I prefer the better things!"

“Smoking helped put me in touch with the realm of the senses.”

"You know you're a stoner when your friends make you a Bob Marley cake."

"Pot always just made me sleepy.”

“Robert Downey Jr. said he started smoking weed at age 8.”

"It [my behavior on the show in 1994] wasn't because I was excited about you [David Letterman]. I think it may have had something to do with the joint I smoked before I came on."

"I'm not a great pothead or anything like that… but weed is much, much less dangerous than alcohol."

In 1975 he wrote “Maverick,” a memoir about his days playing in the NBA. Among other things, Jackson spoke frankly about marijuana use. -- Salon

"I can't claim a Bill Clinton and say that I never inhaled.”

"Bieber both confirmed that he'd been caught smoking weed and apologized for it." -- Huffington Post

“Angelou settled into a job as a waitress and began smoking marijuana with abandon.”

"In 1999, then-Warwick Mayor Lincoln D. Chafee won accolades for his honesty in acknowledging he used marijuana and cocaine as a 1970s student at Brown University."

“The first time I smoked was at home with my mother and step-father.”

“I’ve tried pot, but it doesn’t do much for me.”

"Cocaine didn't interest me. Not at all. I'm way way back in the early pot…"

"The blogger and commentator Andrew Sullivan was busted in July for possessing a small amount of marijuana within the Cape Cod National Seashore."

"As I've already been open about in the past -- and as I assume many would expect -- I made personal choices when I was younger that I neither support nor condone for others and certainly wouldn't encourage through public policy."

"I don't smoke much pot anymore."

"Of course I know how to roll a joint."

“… the one that has the worst effect for me was pot. I felt silly and giggly - I hate feeling like that.”

"Never give up the ganja."

“I went through one period when I smoked a surprising, a really breath-taking, amount of grass almost every night.”

“I enjoy it once in a while. There is nothing wrong with that. Everything in moderation. I wouldn't call myself a pot-head.”

“[Phelps] firmly denies that he takes drugs, suggesting that the notorious photo of him smoking from a bong was a one-time lapse of judgment.”

“…what I did was experiment with a little marijuana like a lot of other people and walked away…”

"CNN anchor Gwen Scott claimed it is common knowledge that Turner sits in his office and smokes marijuana."

“I was hiding out from the celebrity thing, I was smoking way too much [marijuana].”

"I smoke a lot of pot when I write music."

"You bet I did. And I enjoyed it.''

“The owner of a local cannabis café told reporters George Clooney was no stranger there.”

Rush Limbaugh admits that he used cannabis during his recovery from opiate addiction and says that the legalization of marijuana is "a great issue" for the GOP.

“James also revealed he and his teammates smoked marijuana one night after getting access to a hotel room in Akron.”

"I have tried it."

"According to this woman, who requested anonymity because of her current job as a clinical psychologist, "He and Randy came to my house, they knocked on my door, and then they blindfolded me, tied me up, and put me in their car. They took me to their apartment and tried to force me to take bong hits. They'd been smoking pot."

"I did experiment with marijuana when I was a youth."

"I wouldn't answer the marijuana questions. You know why? Because I don't want some little kid doing what I tried."

“As for drugs – well, Gates was certainly not unusual there. Marijuana was the pharmaceutical of choice…”

"Look, I have never made a secret of the fact that I have tried marijuana... About 50,000 times."

"He said he had tried marijuana, enjoyed it, 'but it did not become a habit and I have not tasted it in many years.'"

"Yes." [In response to the question: "Which of you are ready to admit to having used marijuana in the past?"]

"I smoked some weed, and that’s how I finished ‘Izzo.’"

“Do you know how many movies I wrote when I was high?”

"First, [in high school], I smoked a lot of pot...and that’s how I got to know the people ‘half in’ the society of my high school and we waved at each other over the bong. Then I got to know people by making jokes.”

"The White House said today that Judge Clarence Thomas, President Bush's Supreme Court nominee, had smoked marijuana while in college."