First, Rockstar Games Ships
Grand Theft Auto San Andreas for Xbox-R- and PC is the official press
release on the availability of the new GTA game on PC and Xbox first mentioned
last night. On a note related to the release, the
GTAForums
(thanks Tiscali Games) indicate that because the game does not offer an option to disable
pixel shader effects, it will not run on video cards without pixel shader
support, GeForce 4 MX cards are specifically discussed in this thread.

It is already possible to workaround some of the problems with the previous 3D GTA games with 3D-analyze so I give it good odds - I can't say how fast it will run or how good it will look without shadereffects (actually with 3D-analyze telling the game that card supports pixelshaders even if it does not) , but I'm pretty sure it will run.