Are you an ambitious researcher looking for your next challenge? Do you have an established background in biomedical sciences with an interest in biomedical engineering? Do you want to further your career in one of the UKs leading research intensive Universities?

This project is part of a £4M EPSRC Programme Grant on Optimising Knee therapies. The aim of the programme is to develop preclinical testing methods, for early-stage treatments for knee osteoarthritis so their performance can be optimised. In the UK, one third of people aged over 45 have sought treatment for osteoarthritis. The knee is the most common site for osteoarthritis and there is a major unmet clinical need, for effective earlier stage interventions that delay or prevent the requirement for total knee replacement surgery. Such treatments involve replacement of diseased or damaged tissues in the knee joint, such as the anterior cruciate ligament, the meniscus or a small region of cartilage and underlying bone with a regenerative device such as and acellular biological scaffold.

The aim of this project is to further develop and apply processes for the decellularisation of allogeneic and xenogeneic tissue scaffolds (osteochondral, ligament, meniscus, bone) for use in experimental testing and to collaborate with engineers working in the programme in the analysis of tissues post-experimental testing to assess changes in tissue structure and composition.

You will have a PhD or be close to competition in a biomedical science/ bioengineering or a closely allied discipline, with experience of tissue decellularisation related to musculoskeletal tissues, histological techniques and biochemical analysis of tissue composition, and have a proactive approach to working in a multidisciplinary team with engineers, biologists and clinicians.

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Location: Leeds - Main CampusFaculty/Service: Faculty of Biological SciencesSchool/Institute: School of Biomedical SciencesCategory: ResearchGrade: Grade 7Salary: £33,199 to £39,609 p.a.
Due to funding limitations, it is unlikely an appointment will be made above £33,199 p.a.Working Time: 100%Post Type: Full TimeContract Type: Fixed Term (2 years - due to external funding)Closing Date: Sunday 25 August 2019 Downloads: Candidate Brief