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In this thesis, we have focused on the image pre-processing in order to enhance the image information. The main aspects of this enhancement rely on removing any image noise and correcting any intensity bias induced by the scanner. Besides, we also contributed with a new technique based on a multispectral, adaptive, region growing algorithm in order to segment the brain from the rest of the head.
We include, as a pre-processing step, the image registration process, in which we proposed a novel pipeline by using information from multiple modalities to improve the results of this process.
Furthermore, we have also studied the current techniques for the detection and segmentation of WML, proposing a new method based on a previous proposal. Therefore, we presented a tool able to automatically detect and segment WML of Multiple sclerosis and Lupus patients.
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