The treatment portion of this study consists of a 40 minute TMS session 5 days a week (Mon-Fri) for 6 weeks. Other visits include an intake assessment, a pre-treatment MRI, a post-treatment assessment and MRI, and a 6 month follow up visit. Participants are paid for both MRI visits, the post-treatment visit and the follow up visit. Half of participants will receive real TMS, while the other half will receive sham (placebo) TMS.

Organization:

Hartford Hospital’s Institute of Living, Yale University School of Medicine

Principal Investigator:

Gretchen Diefenbach, PhD

Eligibility Criteria:

Individuals with the following will be considered for this study:

Diagnosed with GAD as the principal or co-principal disorder

Clinical Global Impression Score ≥ 4

Hamilton Anxiety Rating Scale ≥ 18

Hamilton Rating Scale for Depression ≤ 17

Fluency in English

Capacity to understand the nature of the study and willingness to sign informed consent form