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Latest & greatest articles for knee osteoarthritis

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on knee osteoarthritis or other clinical topics then use Trip today.

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Viscosupplementation for KneeOsteoarthritis: A Review of Clinical and Cost-Effectiveness and Guidelines Viscosupplementation for KneeOsteoarthritis: A Review of Clinical and Cost-Effectiveness and Guidelines | CADTH.ca Find the information you need Viscosupplementation for KneeOsteoarthritis: A Review of Clinical and Cost-Effectiveness and Guidelines Viscosupplementation for KneeOsteoarthritis: A Review of Clinical and Cost-Effectiveness and Guidelines Published on: June 22, 2017 Project (...) Number: RC0895-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of viscosupplementation for the treatment of adults with osteoarthritis of the knee? What is the cost-effectiveness of viscosupplementation for the treatment of adults with osteoarthritis of the knee? What are the evidence-based guidelines associated with viscosupplementation for the treatment of adults with osteoarthritis of

Treatment of osteoarthritis of the knee: an update review Treatment of osteoarthritis of the knee: an update review Treatment of osteoarthritis of the knee: an update review Newberry SJ, FitzGerald J, SooHoo NF, Booth M, Marks J, Motala A, Apaydin E, Chen C, Raaen L, Shanman R, Shekelle PG. Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Newberry SJ, FitzGerald (...) J, SooHoo NF, Booth M, Marks J, Motala A, Apaydin E, Chen C, Raaen L, Shanman R, Shekelle PG.. Treatment of osteoarthritis of the knee: an update review. Rockville: Agency for Healthcare Research and Quality (AHRQ). Comparative Effectiveness Review No. 190. 2017 Authors' objectives To assess the evidence for the efficacy of the following interventions for improving clinical outcomes in adults with osteoarthritis (OA) of the knee: cell-based therapies; glucosamine, chondroitin, or glucosamine

Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients With KneeOsteoarthritis: A Randomized Clinical Trial. Importance: Synovitis is common and is associated with progression of structural characteristics of kneeosteoarthritis. Intra-articular corticosteroids could reduce cartilage damage associated with synovitis but might have adverse effects on cartilage and periarticular bone. Objective: To determine the effects of intra-articular injection of 40 (...) mg of triamcinolone acetonide every 3 months on progression of cartilage loss and knee pain. Design, Setting, and Participants: Two-year, randomized, placebo-controlled, double-blind trial of intra-articular triamcinolone vs saline for symptomatic kneeosteoarthritis with ultrasonic features of synovitis in 140 patients. Mixed-effects regression models with a random intercept were used to analyze the longitudinal repeated outcome measures. Patients fulfilling the American College of Rheumatology

Comparison of Single Intra-Articular Injection of Novel Hyaluronan (HYA-JOINT Plus) with Synvisc-One for KneeOsteoarthritis: A Randomized, Controlled, Double-Blind Trial of Efficacy and Safety 28291178 2017 03 14 2017 04 18 2017 04 18 1535-1386 99 6 2017 Mar 15 The Journal of bone and joint surgery. American volume J Bone Joint Surg Am Comparison of Single Intra-Articular Injection of Novel Hyaluronan (HYA-JOINT Plus) with Synvisc-One for KneeOsteoarthritis: A Randomized, Controlled, Double (...) -Blind Trial of Efficacy and Safety. 462-471 10.2106/JBJS.16.00469 Viscosupplementation has been widely used for the treatment of kneeosteoarthritis. Because we found no well-controlled trial comparing single-injection regimens of hyaluronan for kneeosteoarthritis, we compared the efficacy and safety of a single intra-articular injection of a novel cross-linked hyaluronan (HYA-JOINT Plus) with a single injection of Synvisc-One in patients with kneeosteoarthritis. In a prospective, randomized

Impact of total knee replacement practice: cost effectiveness analysis of data from the Osteoarthritis Initiative. Objectives To evaluate the impact of total knee replacement on quality of life in people with kneeosteoarthritis and to estimate associated differences in lifetime costs and quality adjusted life years (QALYs) according to use by level of symptoms. Design Marginal structural modeling and cost effectiveness analysis based on lifetime predictions for total knee replacement and death (...) from population based cohort data. Setting Data from two studies-Osteoarthritis Initiative (OAI) and the Multicenter Osteoarthritis Study (MOST)-within the US health system. Participants 4498 participants with or at high risk for kneeosteoarthritis aged 45-79 from the OAI with no previous knee replacement (confirmed by baseline radiography) followed up for nine years. Validation cohort comprised 2907 patients from MOST with two year follow-up. Intervention Scenarios ranging from current practice

Effect of Topical Application of Nigella Sativa Oil and Oral Acetaminophen on Pain in Elderly with KneeOsteoarthritis: A Crossover Clinical Trial. 28344755 2017 03 27 2017 08 16 2008-5842 8 11 2016 Nov Electronic physician Electron Physician Effect of Topical Application of Nigella Sativa Oil and Oral Acetaminophen on Pain in Elderly with KneeOsteoarthritis: A Crossover Clinical Trial. 3193-3197 10.19082/3193 Limited evidence supports Nigella sativa's role as an effective complementary (...) and alternative medicine and the anti-inflammatory effects of Nigella sativa on patients with allergic rhinitis. The aim of this study was to investigate the effect of topical application of Nigella sativa oil and oral acetaminophen on pain in the elderly with kneeosteoarthritis residing in a parents' home in Sabzevar. This study is done as a crossover clinical trial. After obtaining written consent of elderly patients with osteoarthritis of the knee, they were randomly divided into two groups. In step 1

A Prospective Randomized Trial of Prognostic Genicular Nerve Blocks to Determine the Predictive Value for the Outcome of Cooled Radiofrequency Ablation for Chronic Knee Pain Due to Osteoarthritis 29300971 2018 03 08 1526-4637 2017 Dec 28 Pain medicine (Malden, Mass.) Pain Med A Prospective Randomized Trial of Prognostic Genicular Nerve Blocks to Determine the Predictive Value for the Outcome of Cooled Radiofrequency Ablation for Chronic Knee Pain Due to Osteoarthritis. 10.1093/pm/pnx286 (...) Genicular nerve radiofrequency ablation is an effective treatment for patients with chronic pain due to kneeosteoarthritis; however, little is known about factors that predict procedure success. The current study evaluated the utility of genicular nerve blocks to predict the outcome of genicular nerve cooled radiofrequency ablation (cRFA) in patients with osteoarthritis. This randomized comparative trial included patients with chronic knee pain due to osteoarthritis. Participants were randomized

Comparative effectiveness review of platelet-rich plasma for kneeosteoarthritis: a review of reviews Comparative effectiveness review of platelet-rich plasma for kneeosteoarthritis: a review of reviews Comparative effectiveness review of platelet-rich plasma for kneeosteoarthritis: a review of reviews HAYES, Inc Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation (...) HAYES, Inc. Comparative effectiveness review of platelet-rich plasma for kneeosteoarthritis: a review of reviews. Lansdale: HAYES, Inc. Directory Publication. 2017 Authors' conclusions Health Problem: Osteoarthritis (OA) is a painful condition in which the cartilage between the bones degenerates, no longer providing a smooth, gliding surface for motion or adequate cushioning. Because OA damages the cartilage and may ultimately damage the bone, it disrupts how components work together, resulting

Comparative effectiveness review of hyaluronic acid for kneeosteoarthritis: a review of reviews Comparative effectiveness review of hyaluronic acid for kneeosteoarthritis: a review of reviews Comparative effectiveness review of hyaluronic acid for kneeosteoarthritis: a review of reviews HAYES, Inc Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation HAYES, Inc (...) . Comparative effectiveness review of hyaluronic acid for kneeosteoarthritis: a review of reviews. Lansdale: HAYES, Inc. Directory Publication. 2017 Authors' conclusions Health Problem: Osteoarthritis (OA) is a painful condition in which the cartilage between the bones degenerates, no longer providing a smooth, gliding surface for motion or adequate cushioning. Because OA damages the cartilage and may ultimately damage the bone, it disrupts how components work together, resulting in pain, swelling

Intra-articular Corticosteroids for Osteoarthritis of the Knee. Clinical Question: Are intra-articular corticosteroids associated with improvement in pain and physical function compared with sham injection or no intervention in patients with kneeosteoarthritis? Bottom Line: Intra-articular corticosteroids may be associated with moderate improvement in pain and a small improvement in physical function up to 6 weeks after injection. However, the quality of the evidence is low.