In the anti-time future influenced by Q, Picard attains the title of Federation ambassador, and retires by the 2390s, after being married for a time to Captain Beverly Crusher. A recessive tendency for Irumodic Syndrome asserts itself in this timeline, causing the degradation of Ambassador Picard's mental faculties. (TNG: "All Good Things...")

In a war-torn future caused by the occurrence of a red wormhole that destroys Deep Space 9 and threatens the end of reality, Picard survives the destruction of the Enterprises -E and -F, as well as Earth's annihilation by the Grigari, and is an admiral in one faction of Starfleet. Admiral Picard and adjutant Captain Nog are in charge of the project to build a time-traveling supership named USS Phoenix to save time from a cataclysm due to occur in the year 2400. Admiral Picard also seems to suffer from an Irumodic Syndrome-like mental degradation in this timeline. (Pocket DS9: Millennium)

In the Star Trek: Invincible timeline, Picard was promoted an Admiral and was co-head of Operation Federation Protection along with William Ross. It was Picard's task to design new starship series for Starfleet. (Star Trek: Invincible)