Cefamandole

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cephalosporins

The second-generation cephalosporins (
cefamandole, cefaclor, cefotetan, cefoxitin, and cefuroxime) have an extended antibacterial spectrum that includes greater activity against additional species of gram-negative rods. Thus, these drugs are active against
Escherichia coli and
Klebsiella and
Proteus species (though several strains of these...

Second-generation cephalosporins (
e.g., cefuroxime and
cefamandole) and third-generation ones (such as ceftazidime) tend to be more effective against gram-negative bacterial species that are resistant to the first-generation cephalosporins. Second-generation cephalosporins have proven effective against gonorrhea,
Haemophilus influenzae, and the abscesses caused by
Bacteroides...

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