Seeing as Marvel’s Agents of S.H.I.E.L.D. is the only comic book show that we can say without qualms gets better and better every season, we’re hoping we can entice you to watch the premiere of what is sure to be their best season yet. So before the two-hour “Orientation” airs tonight at 8/7c, check out a few hints about what’s in store from the cast and crew’s 100th episode celebration.

1. Mack and Elena Face New Obstacles

After losing his virtual reality daughter Hope last season, Mack will still be suffering the ramifications of his choice to leave her behind. As actor Henry Simmons explained, “It obviously affected [him] a great deal. I think in the first couple of episodes, you see him more or less trying to survive and not really dealing with it in a way. But at some point Mack’s gonna hit the wall and have to face the reality of what just happened.” It’s not only going to affect his outlook on survival and life, it will also shape how he wants to move forward with Elena. Maybe Yo-yo will teach him Spanish? Natalia Cordova-Buckley teased that she has certainly been trying.

Speaking of Elena, now that the Agents of S.H.I.E.L.D. have been sent to space, Cordova-Buckley says they’re not even dealing with the same people anymore. And since they’re going to land in an oppressive system, “A lot is going to happen to [Yo-Yo] because of that. She’s up there whenever someone’s getting hurt; she’ll be the first one there.”

Anything that shocked them about the first two episodes? “Right off the bat, we’re in space,” Henry reminded us.

2. Are Fitzsimmons Cursed?

Agents of S.H.I.E.L.D.show runners Maurissa Tancharoen and Jed Whedon were hit with the shipper question out of the gate, and while they didn’t say much, they had a few words of comfort.“If you stick through the season…” Tancharoen began, only for Whedon to finish off with “Iain’s still on the show, it’ll be fine.”

Even Clark Gregg hopes for a Fitzsimmons reunion, though he bemoaned, “The universe tortures people like me who ship them.” But Iain De Caestecker was more optimistic. “The reason they’re not cursed is because… They find a way through it together.”

Specifically for Fitz himself, Tanchareon informed us that, “The fact that he was Leopold in the Framework and the things that he had done… Each alter identity in that world is derived from the person that you are, so him understanding that and being aware of that moving forward is something that will come into play.”

3. What’s Next For Coulson?

Clark Gregg hinted at Phil and Melinda’s relationship in the wake of the Framework. “You can’t own territory we didn’t really walk down together,” he explained. Due to the deception, Phil and Melinda are going to start over from their friendship and see what happens. “We’re going into season five with some very big, terrifying fish to fry… And [Philinda] remains on the table.”

Gregg also set the scene for an alienating yet exciting season 5 premiere. “We’re in space and we don’t know where we are. There’s people who seem human and we don’t know if they are… And yet I think very quickly there are reasons to believe it’s a good thing we’re here.” The Agents of S.H.I.E.L.D. will be beneficial in the new location.

Given that Coulson and company find themselves in space, are there any aliens they wanted to do on that they finally got the chance to on the show? “Stay tuned,” Executive Producer Jeph Loeb responded.

4. Daisy Stays a Hero

Daisy’s even more of a superhero now than ever before, which means she’s first through the door if anyone needs saving. For actress Chloe Bennet, that means “it’s been a really fun stunt season. People who are into that kind of thing are going to be excited, because there’s a lot of new characters to fight and a lot of new settings.”

She also poked fun of castmate Iain De Caestecker, suggesting another alternate reality where Daisy and Fitz are together. But they both agreed the writers know the characters best. “They really know our dialogue and our sense of humor, so they write and cater towards each actor,” Bennet gushed.

As much as they’re all shaken by what happened in the Framework, Bennet declared that they have more immediate concerns at the moment. “Let’s figure out how to get out of space now.”

5. Welcome, Jeff Ward

Jeff Ward is a new face on Agents of S.H.I.E.L.D. this season, and the mysterious character he is playing is called Deke. As a fan of the show, Ward is thrilled with how his character is introduced. “The people we’re familiar with are in a new environment and they don’t know what going on,” while Deke is acting like more of their guide. “To be the authoritative figure but [also] to be the new guy was an interesting dynamic.”

Ward also hinted at a burgeoning relationship with Daisy, though it will be tumultuous. “We immediately see a little bit of each other in the other person. And sometimes it makes for being really good teammates; sometimes it makes for butting heads. ” Regardless, Daisy is someone that Deke instantly feels connected to.

Producer Jeffrey Bell referred to Deke as an unreliable narrator, which ramps up the mystery surrounding the season-long story. In order to learn more, you’ll have to tune in to ABC tonight at 8/7c!