The Wedding Diary 2 picks up two years after the marriage of Wei Jie (Aniu) and Zhixin (Elanne), when they welcome a new and unexpected addition to their family.

However, all is not well for Wei Jie`s in-laws when Zhixin`s father, Colin (Jack Choo) suffers a stroke, which puts a strain on the couple`s relationship as Zhixin has to step up to handle her father`s business and at the same time, ensure that her mother (Kara Hui) does not fall into depression and anxiety due to her husband`s condition.