The San Francisco VA Health Care System (SFVAHCS) has been a leader in health care for over 75 years, and is known as one of the country's most integrated, state-of-the-art acute medical, neurological, surgical, and psychological health care programs. SFVAMC is home to the largest medical research program in the national VA system, with more than 200 research scientists and clinicians, all of whom are faculty members at the University of California, San Francisco. The Medical Center has 124 operating hospital beds and a 120-bed Community Living Center. Primary and mental health care is provided at community-based outpatient clinics in Santa Rosa, Eureka, Ukiah, Clearlake and San Bruno, with a specialized homeless Veterans clinic located in downtown San Francisco. SFVAMC has National Centers of Excellence for Epilepsy Treatment, Cardiac Surgery, Post-Traumatic Stress, HIV, Renal Dialysis and Primary Care Education, plus many other nationally-recognized research and clinical programs. In 2007, the Integrated Care Clinic was created specifically to meet the health care needs of the newest generation of Veterans.

University of California, San Francisco

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. One of the world's premier health sciences universities, UCSF is San Francisco's second largest employer, with a $5 billion budget and generates an estimated economic impact of $6.2 billion. UCSF Medical Center and UCSF Children's Hospital rank among the top 10 hospitals in the United States; the UCSF Schools of Dentistry, Medicine, Nursing, Pharmacy and Graduate Division all rank among the nation's most prestigious advanced study programs in the health sciences; and UCSF schools are among the top institutional recipients of NIH research funding. UCSF faculty have one of the highest rankings for "scholarly productivity" and five faculty have been awarded Nobel prizes; 41 are members of the National Academy of Sciences; 72 are members of the Institute of Medicine; and 16 are Howard Hughes Medical Institute Investigators.

United States Department of Defense

NCIRE partners with several organizations within the Depatment of Defense to conduct advanced research in military medicine and Veterans health, including:

David Grant USAF Medical Center (DGMC) is the largest inpatient military treatment facility in Air Mobility Command and the second largest in the United States Air Force. It provides a full spectrum of care to a prime service area population of nearly 96,000 TRICARE eligible beneficiaries in the immediate San Francisco-Sacramento vicinity and 377,000 Department of Veterans Affairs Northern California Health Care System eligible patients from 17 counties covering 40,000 square miles. One of the premier Joint Commission-accredited teaching hospitals in the United States, DGMC provides postgraduate training programs in family medicine, radiology, surgery, transitional care, dentistry, oral surgery, pharmacy and social work, as well as training for technicians and clinical nurses. Situated on a 55-acre campus at the entrance to Travis Air Force Base, DGMC includes the VA Fairfield Outpatient Clinic, a Clinical Investigation Facility, and a community-supported Fisher House. DGMC also serves as a primary staging platform for combat support of Operation Iraqi Freedom and Operation Enduring Freedom, as well as humanitarian missions throughout the world.

Defense Centers of Excellence for Psychological Health and Traumatic Brain Injury (DCoE) together with the National Intrepid Center of Excellence (ICoE) assesses, validates, oversees and facilitates prevention, resilience, identification, treatment, outreach, rehabilitation and reintegration programs for psychological health (PH) and traumatic brain injury (TBI) to ensure that the Department of Defense meets the needs of the nation's military communities, warriors and families. DCoE partners with the Department of Veterans Affairs, and a national network of military and civilian agencies, community leaders, advocacy groups, clinical experts, and academic institutions to establish best practices and quality standards for the treatment of PH and TBI. Its work is carried out across these major areas: clinical care; education and training; prevention; research; and patient, family and community outreach. In addition, DCoE is working to tear down the stigma that still deters some from seeking psychological health care with its Real Warriors Campaign.

Military Operational Medicine Research Program (MOMRP) provides biomedical solutions that protect Soldiers and enhance their performance in operational and training environments that include multiple stressors. Its core biomedical research capabilities are organized into 13 areas ranging from environmental medicine and bioenergetics, injury sciences, and systems hazards to neuropsychological stress and performance. The MOMRP conducts collaborative research with university and commercial laboratories and other federal agencies oriented toward solving critical problems facing the Army today and in the future. Service and platform-specific issues are addressed through close coordination with Navy and Air Force counterparts.

Telemedicine and Advanced Technologies Research Center (TATRC) performs medical reconnaissance and special operations to address critical gaps that are underrepresented in DoD medical research programs. TATRC is an office of the headquarters of the US Army Medical Research and Materiel Command (USAMRMC). TATRC fosters research on health informatics, telemedicine/m-Health, medical training systems and computational biology, and promotes and manages science and engineering in other key portfolios. Through an extensive network of partners, TATRC is focused at both ends of the research spectrum, exploring models of high risk and innovative research, and putting research findings into the hands of warfighters while looking toward wider civilian utility. TATRC augments core medical research programs through special funding and partnership opportunities.