Stavros Liatis, Nikolaos Katsilambros Sulfonylureas and non-sulfonylurea insulin secretagogues (meglitinides) exert their antidiabetic effects by binding to the sulfonylurea receptor (SUR) on the beta-cell, which regulates the activity of an ATP-dependent potassium channel.1

Hypoglycemia is bad, and hypoglycemia unawareness is worse. Drug manufacturers may be making better insulin delivery systems to combat hypoglycemia, but they haven’t yet been able to eliminate the chance that a low can happen. Hypoglycemia Treatment Quick Hits.

” Asymptomatic hypoglycemia can be like a boogeyman under the bed for people with diabetes. Clinically, a bout of asymptomatic hypoglycemia involves a measured plasma glucose below ?70 mmol/L), not accompanied by some or all of the typical symptoms of hypoglycemia.

Some people don’t understand why people with diabetes get upset at the price of insulin. They see insulin for sale at a relatively reasonable price in Walmart and don’t see the problem. What they don’t know is that these Walmart insulins just don’t perform nearly as well as the more expensive insulins, and that gap in performance can have a very negative effect on the health of people with diabetes. These insulins are not interchangeable. Commentary. MORE >>

For her, the sacrifice, including many, many episodes of hypoglycemia, has been well worth it. There is no rhyme nor reason to his glucose levels, and he has a great deal of lipohypertrophy, which is a thickening underneath the skin that makes absorption of injected insulin difficult and irregular. The bionic pancreas requires patients wear two insulin pumps, one containing insulin and the other containing glucagon, a well as a glucose sensor. MORE >>

It seems incongruous to have to worry about hypoglycemia more during a hospital stay than in daily life, but diabetes specialists warn that people with diabetes who are hospitalized face a greater risk of experiencing hypoglycemic events in the hospital. Our study showed that patients with diabetes who have hypoglycemia in the hospital are at higher risk for death both while hospitalized and for at least a year after discharge,” says Dr. Turchin in an email interview. MORE >>