When I was a high school student, a Japanese astronaut went into space with Medaka fish. The fish became famous as the “first vertebrate mating in space”. The experiment opened my eyes to the field of “Space Biology”. I became a student of the Department of Biology at Ochanomizu University. In 2000, "JUSTSAP S*T*A*R*S Program" started to accept candidates for a space experiment with aquatic animals from all over Japan. I applied it to the Medaka fish experiment and was selected as the primary student investigator. The road to success of the space experiment was winding. I would like to introduce my space experiment experience and discuss my current research at the Japan Aerospace Exploration Agency (JAXA) Biomedical Research Office.