To the Editor: Dr Grundy1 discussed
evidence that C-reactive protein at baseline is independently associated with
an increased risk of hypertension in women. As he indicated, the mechanism
remains uncertain. Recent studies2,3 suggest
that women with elevated C-reactive protein levels may be at risk for extensive
periodontal disease at baseline and subsequent tooth loss during follow-up.
A recent population-based study4 found that
the intake of some nutrient-rich foods correlated with significantly lower
serum levels of beta carotene, folate, and vitamin C in denture-wearers. Antioxidant
vitamins are important in the underlying cause of hypertension.5 Dietary
pattern change during follow-up may be one mechanism that links C-reative
protein level with the risk of developing hypertension.