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Aids Pathogenesis

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A gradual destruction of the naive and memory CD4+ T-lymphocyte populations is the hallmark of HIV-1 infection, with AIDS being the last disease stage (figure 4).. Immune activation predicts disease progression74 and, thus, seems to be a central feature of pathogenic HIV-1 infections.Pathogenesis of human immunodeficiency virus infection.. The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large number of different cells in the body and escaping the host immune response against it. Scott Sieg, PhD, Center for AIDS Research, Case Western University. HIV and the Intricate Relationship between Viral Pathogenesis and Immune Defenses .PATHOGENESIS OF AIDS how does HIV cause AIDS? DEFINITIONS. â–« HIV: human immunodeficiency virus. HIV is a member of the lentivirus family, a subgroup . Accumulating clinical observations suggest that microbial translocation might affect HIV disease progression, response to therapy, and non-AIDS comorbidities . THE ACQUIRED immunodeficiency syndrome (AIDS) is caused by a newly recognized member of the lentivirus family, the human immunodeficiency virus .