The CCR multi-dimensional concept (8 key dimensions and 28 reference parameters) intends to capture the essential elements of Creative Classrooms which can be seen as ‘live ecosystems’ that constantly evolve over the time, mainly depending on the context and the culture to which they pertain. Focus is on the innovative pedagogical practices and on the systemic approach that is needed for the sustainable implementation and progressively scaling up of ICT-enabled innovative learning environments.