One tube. Many answers.

Use DNA or RNA for SNP, CNV, fusion, and indel detection

When analyzing suspected variants in genetic diseases, you need a discovery tool that is both rapid and cost-effective for analyzing multiple genes. Ready-to-use, made-to-order, and on-demand Ion AmpliSeq NGS panels can help.

Ion AmpliSeq panels consist of a pool of oligonucleotide primer pairs, each pair designed to amplify a specified genomic region. Each panel can be designed to interrogate all bases across a gene, or it can be focused on specific mutation hotspots.

Gene panels on demand, how and when you want them

Ion AmpliSeq On-Demand panels bring smaller pack sizes and an optimized catalog of pre-tested genes to custom NGS panels, so you can iterate panel design for human disease research with efficiency and convenience.

For maximum flexibility, simply select a subset of targets and enter your specific genomic content online using the Ion AmpliSeq Designer tool, and we will design and create customized Ion AmpliSeq panels just for you. Choose from a number of reference genomes or upload your own reference sequence.

Power and speed for targeted NGS analysis

Ion AmpliSeq panel results from Boston Children’s Hospital, USA

Applications of targeted NGS panels for clinical research of primary immunodeficiency diseases

Dr. Janet Chou and Wayne Bainter discuss the application of the Ion AmpliSeq Primary Immune Deficiency (PID) Research Panel v2 to accelerate and improve the search for causal variants in clinical research of PIDs.