Available hosts

Available applications

Background of HMGB3 antibody

This gene encodes a member of a family of proteins containing one or more high mobility group D-binding motifs. The encoded protein plays an important role in maintaining stem cell populations, and may be aberrantly expressed in tumor cells. A mutation in this gene was associated with microphthalmia, syndromic 13. There are numerous pseudogenes of this gene on multiple chromosomes. Altertive splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].