ESRD Frequently Follows Dialysis-Dependent AKI

In a study, end-stage renal disease developed in 56% of patients discharged from a hospital with acute kidney injury requiring dialysis.

The following article is part of conference coverage from Kidney Week 2017 in New Orleans hosted by the American Society of Nephrology. Renal & Urology News staff will be reporting live on medical studies conducted by nephrologists and other specialists who are tops in their field in acute kidney injury, chronic kidney disease, dialysis, transplantation, and more. Check back for the latest news from
Kidney Week 2017.

NEW ORLEANS—Patients discharged from a hospital with acute kidney injury requiring dialysis (AKI-D) have a high incidence of transitioning to end-stage renal disease (ESRD), researchers reported at the American Society of Nephrology's Kidney Week 2017 meeting.

Possible risk factors associated with the development of ESRD include baseline chronic kidney disease (CKD), hypertension, and diabetes.

ESRD developed in more than half of AKI-D patients (56%). Serum creatinine increased from 1.4 mg/dL at baseline to 5.8 mg/dL at dialysis initiation with limited urine output of 290 mL/day. In univariate analysis, factors associate with the development of ESRD included male gender, CKD, hypertension, diabetes mellitus, and heart failure.

He added that the presence of factors associated with transition to ESRD, including baseline kidney disease, diabetes, and hypertension, should prompt nephrologists to discuss the likelihood of poor renal recovery and appropriate treatment options with patients and their families.