Mother to infant transmission of coinfection by human immunodeficiency virus and hepatitis C...
Nigro, G.; D’Orio, F.; Catania, S.; Badolato, M. C.; Livadiotti, S.; Bernardi, S.; D’Argenio, P.
1997-03-01 00:00:00
The prevalence and the clinical course of hepatitis C virus (HCV) infections were studied in 23 HIV-1-infected children, who were born to 22 mothers with HIV-1/HCV coinfection. During the follow-up only two children (8.7%) showed persistent anti-HCV antibodies and circulating HCV RNA. Both children, who were aged 10 and 10.6 years respectively at the end of follow-up, had chronically-evolving liver disease and autoimmune thrombocytopenia but no signs of progressive HIV disease. Based on our experience, vertically-acquired HIV-1/HCV coinfection is less frequent than is generally reported and may be associated with the development of chronic thrombocytopenia in addition to liver disease. Moreover, perinatal HIV-1/HCV coinfection appears to be associated with a slow progression of HIV disease.
http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.pngArchives of VirologySpringer Journalshttp://www.deepdyve.com/lp/springer-journals/mother-to-infant-transmission-of-coinfection-by-human-immunodeficiency-J0zqK49LMk