About This Project

Ketamine is a very rapidly-acting and safe antidepressant medication given as an intravenous infusion, during which people may experience a brief dissociative state. Extensive research into the mechanism of ketamine has focused on physical/chemical changes in the brain, but little is known about the therapeutic role of the experience itself. Many describe a sense of profound awe during their treatment, and we want to see if the feeling of awe and antidepressant effects are correlated.