TERMS OF USE

This Web site, including all of the content, applications, and services offered from time to time by, on, or through the site (the “Site”) is offered to you, the user, (“you” or “User”) conditioned solely upon your acceptance of all the provisions of this Agreement. By accessing and using the Site, you agree to abide by all the provisions of this Agreement.

Patent, Trademark and Copyright

This Site is operated by BioMed Valley Discoveries, Inc. (“BVD”). BVD is the owner of all right, title and interest in this Site and its contents, including without limitation, all patents, copyrights, trademarks, service marks, trade dress, trade names and any and all other Intellectual Property whether now known or here after existing and all of the good will therein (“Intellectual Property”). The Site is for your personal, noncommercial use only, with no transfer of title.

You may not modify, copy, distribute, transmit, display, perform, reproduce, publish, license, create derivative works from, transfer, sell, or make any other use of any of the content obtained from the Site. You may not use any of the Site content on any other Web site or networked computer environment, or in any format or medium, whether now known or hereafter existing. You may not remove any Intellectual Property or legal notice from any content downloaded from the Site.

Third Party Web Sites and Access

This Site may contain links and pointers to Internet sites maintained by third parties. BVD does not operate or control in any respect, or endorse, the content found on such third-party sites. You assume sole responsibility for use of third party links and pointers.

You further acknowledge that all connections to, and transmissions through, the Internet, including your access to this Site, are subject to opportunities for access by third parties. As a result, by accessing the Site, you acknowledge that you have no legitimate expectation of privacy in such connections and/or transmissions, and BVD shall not be responsible for any such third party access to such connections and/or transmissions.

Privacy Policy; Limited Authorization to Use and Disclose Your Information

You hereby acknowledge that BVD may from time to time collect, retain, and disclose information and data collected from you in accordance with BVD’s Privacy Policy located on the Site at https://biomed-valley.com/privacy-policy/ (the “Privacy Policy”). You hereby consent, as a condition of your use of the Site, to the collection, use, processing, and transfer of your information as described in this Agreement and the Privacy Policy.

Modification of this Agreement

BVD reserves the right to change this Agreement at any time by publishing a revised version of this Agreement on the Site. You are responsible for regularly reviewing this Agreement. Continued use of the Site following any such changes means you accept and will abide by these changes.

Warranty Disclaimer; Limitation of Liability

THE MATERIALS IN THIS SITE ARE PROVIDED “AS IS” AND WITHOUT WARRANTIES OF ANY KIND, EITHER EXPRESS OR IMPLIED, TO THE FULLEST EXTENT PERMISSIBLE PURSUANT TO APPLICABLE LAW. BVD DISCLAIMS ALL WARRANTIES, EXPRESS OR IMPLIED, INCLUDING, BUT NOT LIMITED TO, IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE, TITLE AND NONINFRINGEMENT. NEITHER BVD NOR ANY PERSON ASSOCIATED WITH BVD WARRANTS THAT THE SITE WILL BE OPERATED FREE OF DELAYS IN TRANSMISSION, FAILURE IN PERFORMANCE, COMPUTER VIRUSES, INACCURACIES OR ERRORS IN THE MATERIALS, OR OTHER ERRORS OR DEFECTS. YOU USE THIS SITE AT YOUR OWN RISK. YOU UNDERSTAND AND EXPRESSLY AGREE THAT NEITHER THIS SITE OR THE CONTENT OF THIS SITE CONSTITUTES MEDICAL ADVICE AND YOU AGREE YOU HAVE NOT RELIED ON THIS SITE, IN ANY RESPECT, FOR MEDICAL ADVICE.

UNDER NO CIRCUMSTANCES, INCLUDING BUT NOT LIMITED TO BREACH OF CONTRACT, TORT OR NEGLIGENCE, WILL BVD OR ITS AFFILIATES, OR ITS OR THEIR LICENSORS, SERVICE PROVIDERS, EMPLOYEES, AGENTS, OFFICERS, OR DIRECTORS, BE LIABLE FOR DAMAGES OF ANY KIND, INCLUDING WITHOUT LIMITATION ANY DIRECT, INDIRECT, SPECIAL, PUNITIVE, INCIDENTAL OR CONSEQUENTIAL DAMAGES, THAT ARISE OUT OF OR IN CONNECTION WITH THE USE OF THE SITE OR WITH THE DELAY OR INABILITY TO USE THE SITE, OR FOR ANY INFORMATION, HARDWARE, SOFTWARE, PRODUCTS AND SERVICES OBTAINED THROUGH THE SITE, OR OTHERWISE ARISING OUT OF THE USE OF THE SITE, EVEN IF ADVISED OF THE POSSIBILITY OF DAMAGES. BECAUSE SOME STATES/JURISDICTIONS DO NOT ALLOW THE EXCLUSION OR LIMITATION OF LIABILITY FOR CONSEQUENTIAL OR INCIDENTAL DAMAGES, THE ABOVE LIMITATION MAY NOT APPLY TO YOU.

Indemnification

You agree to indemnify and hold harmless BVD, its suppliers, and any third parties assisting in the operation of the Site from any claims, liabilities, and expenses (including reasonable attorney’s fees) that may arise from your use of the Site in any way or from your breach of the terms of this Agreement.

General

BVD reserves the right to make any and all changes to the Site at its sole discretion without notice to users. BVD reserves the right to deny access to the Site to anyone at any time, and to terminate this Agreement at any time without notice in its sole discretion.

This Agreement shall be deemed to include all other notices, policies, disclaimers, and other terms contained in the Site, including without limitation the Privacy Policy; provided, however, that in the event of a conflict between such other terms and the terms of this Agreement, the terms of this Agreement shall control.

This Agreement is governed by the laws of the State of Missouri, in the United States of America, without regard to conflicts of law provisions. You consent to the exclusive jurisdiction and venue of courts of Kansas City, Missouri, in the United States of America, in all disputes arising out of or relating to the use of the Site. Use of the Site is unauthorized in any jurisdiction that does not give effect to all provisions of these terms and conditions, including without limitation this paragraph.

If any provision of this Agreement is determined to be invalid or unenforceable pursuant to applicable law including, but not limited to, the warranty disclaimers and liability limitations set forth above, then the invalid or unenforceable provision will be deemed superseded by a valid, enforceable provision that most closely matches the intent of the original provision and the remainder of the Agreement shall continue in effect.

This Agreement constitutes the entire agreement between you and BVD with respect to the Site and it supersedes all prior or contemporaneous communications and proposals, whether electronic, oral or written, between you and BVD with respect to the Site. A printed version of this Agreement and of any notice given in electronic form will be admissible in judicial or administrative proceedings based upon or relating to this Agreement to the same extent and subject to the same conditions as other business documents and records originally generated and maintained in printed form.

Any rights not expressly granted herein are reserved to BVD.

BVD’s waiver of any condition or covenant of this Agreement, or its failure to exercise a right or remedy available to it, shall not constitute a further waiver of the same or any other condition, covenant, right, or remedy.

Dr. Martin Teresk is an Associate Director of Chemistry at BioMed Valley Discoveries. Prior to joining BioMed Valley Discoveries, Martin served as Director of Process Development at Orbis Biosciences, where he led the development and manufacturing scale-up of the company’s particle engineering technology.

He previously held key positions in process research and development at Gilead Sciences, providing scientific and technical leadership in developing scalable chemical processes for the manufacture of drug substances from preclinical development through commercialization. Martin received a BS in Chemistry from Purdue University and a PhD in Organic Chemistry from the University of Texas at Austin.

Jessica Box is a Scientist in the Translational Sciences group at BioMed Valley Discoveries. Prior to joining BioMed Valley Discoveries, Jessica was the Laboratory Manager at IntelligeneCG, where she oversaw the genomics laboratory and accessioning department.

She has experience in several facets of research including: basic biomedical research, clinical research, and industry. Jessica received a BS degree in biology from Baker University.

JONATHAN S. THOMASPresident and Chief Executive Officer, American Century Investments

Mr. Jonathan S. Thomas is President and Chief Executive Officer of American Century Investments. Mr. Thomas joined American Century in 2005 as Chief Financial Officer and Executive Vice President, and a member of the American Century Companies Board of Directors. He became CEO in March 2007.

Prior to joining American Century, Mr. Thomas was Global Chief Operating Officer and Managing Director of the Investment Management division at Morgan Stanley in New York City. Mr. Thomas received a BA in Economics from the University of Massachusetts and a MBA from Boston College.

Mr. Roderick L. Sturgeon is currently Executive Vice President and Chief Financial Officer of the Stowers Institute for Medical Research. Mr. Sturgeon joined the Stowers Institute in February 2007 from a position as Senior Vice President, Personal Expression Group Finance at Hallmark Cards, Inc.

Mr. Sturgeon received a bachelor’s degree from Kansas State University and a MBA from the University of Missouri, Kansas City. He serves on the Kansas State University Business College Advisory Board and the Community National Bank Board.

WILLIAM B. NEAVES, PhDPresident Emeritus, Stowers Institute for Medical Research

Dr. William B. Neaves is President Emeritus of the Stowers Institute for Medical Research. Previously, Dr. Neaves served as Chief Executive Officer of the Stowers Institute from 2000 to 2010. Prior to joining the Stowers Institute, he held various positions at the University of Texas Southwestern Medical Center at Dallas.

Dr. Neaves currently serves as a member of the Boards of Directors of the Stowers Institute for Medical Research, Stowers Resource Management, BioMed Valley Corporation, and BioMed Valley Discoveries. Dr. Neaves received an AB magna cum laude with highest honors in biology from Harvard College in 1966 and a PhD in anatomy from Harvard University in 1969.

Dr. Brent L. Kreider serves as Chief Operating Officer of both BioMed Valley Discoveries and the Stowers Institute for Medical Research. In his previous position as Vice President and Global Head of Scientific Operations at the Novartis Institutes for Biomedical Research, Dr. Kreider provided senior management oversight to scientific support functions at institute sites throughout North America, Europe, and Asia.

Prior to joining Novartis, he held senior leadership positions at three biotech companies. Dr. Kreider received a PhD in microbiology from the University of Pennsylvania and performed postdoctoral research at St. Jude Children’s Research Hospital.

Mr. Clifford W. Illig is Vice Chairman of the Board and Co-Founder of Cerner Corporation, one of the world’s largest suppliers of healthcare information technology solutions, healthcare devices, and related services.

He focuses on growing and expanding Cerner’s market-oriented business units, key strategic relationships, and priority corporate initiatives. Mr. Illig serves some significant regional civic boards and organizations. Mr. Illig received a degree in accounting and business administration from the University of Kansas.

ABBY FREEMANFormer Executive Vice President for Administration, Stowers Institute for Medical Research

Ms. Abby Freeman is the former Executive Vice President for Administration at the Stowers Institute for Medical Research. Prior to joining the Institute, Ms. Freeman held positions at The University of Texas Southwestern Medical Center at Dallas including Director of the Graduate School of Biomedical Sciences, Equal Opportunity and Minority Affairs Officer, and Vice President for Human Services Administration.

Ms. Freeman previously held leadership positions with the Young Women’s Christian Association (YWCA). Ms. Freeman earned a BA in business administration from Huston-Tillotson College in Austin, Texas. She serves as a member of the Boards of Directors of the Stowers Institute for Medical Research and American Century Companies.

Dr. David M. Chao serves as President and Chief Executive Officer of BioMed Valley Discoveries and the Stowers Institute for Medical Research. Prior to joining BioMed Valley Discoveries, Dr. Chao was head of operations for strategic alliances at the Novartis Institutes for Biomedical Research. His previous positions also include co-founder and executive at two biotech start-ups and consultant at McKinsey & Company.

After receiving combined MA and BA degrees in biology from Harvard University, Dr. Chao received a Ph.D. in biology from the Massachusetts Institute of Technology where he was a predoctoral fellow of the Howard Hughes Medical Institute. He serves on the board of the Stowers Institute for Medical Research, American Century Companies, Nectagen, and the Pembroke Hill School.

RICHARD W. BROWNChairman of the Board, BioMed Valley Discoveries, Inc.
Chairman of the Board, American Century Companies, Inc.
Chairman of the Board, Stowers Institute for Medical Research and Stowers Resource Management

Mr. Richard W. Brown serves as Chairman of the Board for BioMed Valley Discoveries, American Century Companies, Stowers Institute for Medical Research, and Stowers Resource Management. Mr. Brown has also served as Chairman, President, and Chief Executive Officer of Stowers Resource Management and BioMed Valley Corporation.

Mr. Brown was previously President and Chief Executive Officer of Health Midwest from 1993 to March 2003. Mr. Brown received a MHA from the School of Medicine at Washington University in St. Louis, Missouri, and a BA in Biology from Phillips University.

Dr. Anna Groover is a Scientist in the Translational Sciences group at BioMed Valley Discoveries, where she manages day-to-day clinical operations for clinical trials involving BVD-523, a selective, reversible, ERK1/2 inhibitor.

Anna joined BioMed Valley Discoveries after completing her PhD in anatomy and cell biology at the University of Kansas Medical Center. She received a BS degree in biology from Baylor University.

Deb Knoerzer is an Associate Director of Translational Sciences at BioMed Valley Discoveries. Prior to joining BioMed Valley Discoveries, Deb was Vice President of Research Operations for Horizon Discovery where she led the research operations for multiple sites within the US.

She has a vast range of experience in both small and large organizations, serving as Chief Operating Officer at SAGE labs and holding a variety of senior positions during her 19 years within the pharmaceutical industry including positions at Pfizer, Pharmacia, Searle, and Monsanto. Deb received a BS in biological sciences from Illinois State University and a MS in biological sciences from Washington University School of Medicine in St. Louis.

Dr. Caroline Emery is an Associate Director of Translational Sciences at BioMed Valley Discoveries. Previously, Carrie held a position in early pharmaceutical development at Novartis Oncology, where she supported the evolution of novel agents into the clinic.

She earned her PhD in developmental genetics from the University of Oxford, UK, and completed postdoctoral training at the Dana-Farber Cancer Institute and Harvard University, where she studied mechanisms of resistance to targeted therapies in melanoma. Carrie received a BSc degree in pathology and microbiology from the University of Bristol, UK.

Dr. Halle Zhang is a Director and Project Leader at BioMed Valley Discoveries, where she leads the clinical development of Clostridium novyi-NT, a bacterial oncolytic therapy. Prior to joining BioMed Valley Discoveries, Halle served as a Clinical Trial Lead within the Harvard Catalyst network.

Her previous positions also include LAM Foundation Research Fellow at Harvard TH Chan School of Public Health and Research Scientist at Tufts University, where she examined cell signaling in cancer and metabolic diseases. Halle is an RN with over ten years of clinical experience in medical, surgical, pediatric, and operating room settings. Halle received a Master in Medical Sciences in immunology and a PhD in medicine from the University of Birmingham, UK.

Dr. Dean Welsch is an Executive Director of Translational Sciences and Head of Pharmacology at BioMed Valley Discoveries. Prior to joining BioMed Valley Discoveries, Dean held positions of increasing responsibility in research and development at Monsanto, Searle, Pharmacia, and Pfizer.

Prior to leaving Pfizer, he was Senior Director and Research Fellow in the company’s Indications Discovery Unit, where he was responsible for identifying and validating through clinical proof-of-concept new indications for development compounds. Dean received a BS in Chemistry from Hope College, a PhD in Biochemistry from the University of Minnesota, and performed postdoctoral research in the lab of Dr. Paul Friedman at Merck Sharpe and Dohme Research Labs.

Dr. David M. Chao serves as President and Chief Executive Officer of BioMed Valley Discoveries and the Stowers Institute for Medical Research. Prior to joining BioMed Valley Discoveries, Dave was head of operations for strategic alliances at the Novartis Institutes for Biomedical Research. His previous positions also include co-founder and executive at two biotech start-ups and consultant at McKinsey & Company.

After receiving combined MA and BA degrees in biology from Harvard University, Dave received a PhD in biology from the Massachusetts Institute of Technology where he was a predoctoral fellow of the Howard Hughes Medical Institute. Dave serves on the board of the Stowers Institute for Medical Research, American Century Companies, Nectagen, and the Pembroke Hill School.

Dr. Brent L. Kreider serves as Chief Operating Officer of both BioMed Valley Discoveries and the Stowers Institute for Medical Research. In his previous position as Vice President and Global Head of Scientific Operations at the Novartis Institutes for Biomedical Research, Brent provided senior management oversight to scientific support functions at Institute sites throughout North America, Europe, and Asia.

Prior to joining Novartis, he held senior leadership positions at three biotech companies. Brent received a PhD in microbiology from the University of Pennsylvania and performed postdoctoral research at St. Jude Children’s Research Hospital.

Gary DeCrescenzo is a consultant at BioMed Valley Discoveries. Prior to joining BioMed Valley Discoveries, Gary was Senior Director of World Wide Medicinal Chemistry at Pfizer Inc, where he oversaw medicinal chemistry and early chemical development.

He previously held senior leadership positions in research and development at Pharmacia Corporation and GD Searle. Gary received a BS in Chemistry and a MS in industrial chemistry from the University of Central Florida.