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L-Ornithine is a non-essential amino acid, metabolized to generate L-arginine, which is further incorporated into proteins. α-Ketoglutarate is a key intermediate in the Krebs cycle, coming after isocitrate and before succinyl CoA. Acting as a co-substrate, α-Ketoglutarate also plays important function in oxidation reactions involving molecular oxygen.http://www.creative-peptides.com/product/l-ornithine-ketoglutarate-monohydrate-item-10-101-118-72.html