Ondansetron (Zofran) is a moderately priced drug used to treat nausea and vomiting caused by chemotherapy. It is also used to prevent or treat nausea and vomiting after surgery. This drug is more popular than comparable drugs. It is available in both brand and generic form. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost. The lowest GoodRx price for the most common version of ondansetron is around $8.89, 94% off the average retail price of $172.91. Compare serotonin antagonists.

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