We currently run autotunes every couple of weeks, however we are in need of daily maintenance indicators. Are there any benefits to manual tuning that would outweigh autotuning and give us a daily status? I'm looking for a "heartbeat" for the instrument's performance that we can track from day to day, and ideally, we would manually adjust to maintain the same performance over time.

I've seen guidance documents for tuning Agilent GC MS single quads, but I'm having a difficult time finding anything similar for triple quads. Any direction or insight would be greatly appreciated!