Tracking outcomes from first episode psychosis in Ontario: A descriptive multicentre study examining the outcomes and predictors of outcome in four first episode psychosis programs1 edition

Tracking outcomes from first episode psychosis in Ontario: A descripti ...

Natasja M. Menezes

Tracking outcomes from first episode psychosis in Ontario: A descripti ...
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Tracking outcomes from first episode psychosis in Ontario: A descriptive multicentre study examining the outcomes and predictors of outcome in four first episode psychosis programs.

About the Book

Objectives. Research from First Episode Psychosis (FEP) programs suggests that outcome from schizophrenia-spectrum illnesses may be better and more heterogeneous than previously reported. This study examines one-year outcome and its predictors, for patients in four Canadian FEP programs.Methods. Secondary data analysis of data from a prospective cohort of 200 patients was conducted. Descriptive and regression analyses were used to examine primary symptomatic (Positive and Negative Syndrome Scale= PANSS) and functional (Social and Occupational Functioning Assessment Scale =SOFAS) outcomes, several secondary outcomes, and their predictors. Missing data was addressed using multiple imputation.Results. Symptomatic remission (74%) exceeded functional recovery (51%); PANSS negative (six months) and site were significantly associated with symptomatic and functional outcomes.Conclusion. FEP samples have higher rates of good outcome than previously reported. Symptoms account for significant variance in later outcome in symptomatic and functional domains. Controlling for site differences may be an important methodological issue.