PRL-3 (catalytic domain) (human), (recombinant) (GST-tag)

Product Specification

Produced in E. coli. The catalytic domain of PRL-3 (aa 2-173) is fused at the N-terminus to a GST-tag.

UniProt ID:

O75365

Application Notes:

Useful for the study of enzyme kinetics and regulation, dephosphorylation of target substrates, and inhibitor screening.

Shipping:

Shipped on Blue Ice

Long Term Storage:

-20°C

Scientific Background:

PRL phosphatases comprise a class of small phosphatases with oncogenic activity, which are prenylated at their C-termini. PRL-3 is overexpressed in colon tumors metastasizing to the liver, but not in normal colorectal epithelium.