XP Screen

Upgraded with the Anderson−Evans polyoxotungstate [TeW6O24]6− (TEW) as universal additive, the XP Screen promotes protein crystallization even for most challenging targets and improves diffraction quality of protein crystals[1]. Its potential has been shown in the new protein structures of aurone synthase from Coreopsis grandiflora[2-4] (PDB code: 4Z12, 4Z13) and mushroom tyrosinase PPO4 from Agaricus bisporus[6,7] (PDB code: 4OUA). The model protein lysozyme crystallized into a new crystal form[5] (PDB code: 4PHI).
The XP Screen is a TEW-optimized JBScreen Basic: 96 of the most prominent crystallization conditions complemented with TEW as "glue" for protein molecules.

TEW...

is highly soluble in aqueous solutions and stable over a wide pH range