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Combining Medications

Advil® is committed to your safety. When taking medication, it is important to understand the potential for interactions with other medication. If you are taking supplements, prescription medications or other over the counter drugs, make sure you consult with your doctor before taking Advil®.

Advil® is a nonsteroidal anti-inflammatory drug (NSAID) and should not be taken with any other product containing:

Ibuprofen (like Motrin®)

Naproxen (like Aleve® or Midol®)

Aspirin

Will Advil® interact with my prescription medication?

Interactions vary depending on the type of prescription. It's important to speak with your doctor or pharmacist and read the drug information that accompanies your prescription to understand how it may interact with other medications.

Can I take Advil® and acetaminophen together?

Talk to your doctor before combining Advil® with other medications. Due to potential negative interactions, don’t take Advil® with naproxen or aspirin.

Can Advil® be taken with antibiotics?

Yes. It depends on the medication, but generally there’s no need to avoid taking Advil® alongside antibiotics.

Does Advil® interact with my opioid medication?

Talk to your doctor before taking Advil® with an opioid medication, since some opioids are already combined with NSAIDs.

It’s important to know that studies have shown that taking ibuprofen (Advil®) can reduce the amount of opioids needed for pain relief, and in some cases they’re even prescribed together.

Can Advil® be taken with NyQuil®?

Some cold remedies like NyQuil® already contain pain relieving ingredients. So watch out for ingredients and don’t take Advil® with any cold medication containing other forms of ibuprofen (like Motrin®), naproxen (like Aleve® or Midol®), or aspirin. It is important to read the label before taking any medication to understand uses, interactions and potential side effects.