Open "Setup" in the root game directory. There the relevant options should be these set so:

Triple buffering - off /not pressed/

Vertical synchronization - off

Bit Depth - 32

Texture quality size

True color - off

Low detail - off

Compressed - off

lightmap quality size

Truecolor - off

Software mixing - off

Disable EAX - off

Expert settings

Hardware transform lightning - off

Suspend when inactive - on

Multipass rendering - on

Clip always - on

The other settings like resolution etc are irrelevant. They may be relevant though for some computers and monitors if they don't maintain that resolution chosen. However with these settings the Mod should run on most computters without further problems. It was tested with them and the 2.5 Traffic Mod as city daytime, never crashed.