NSAIDs have the potential to increase the risk of heart attack, stroke, skin reactions, and serious stomach and intestinal bleeding. These risks are greater if NSAIDs are taken at higher doses or for longer periods than recommended.

Aspirin, unlike other NSAIDs, has been shown to reduce the risk of heart attack and stroke. It does carry the risks of serious stomach and intestinal bleeding as well as skin reactions.

Because aspirin can increase the risk of bleeding, it is not recommended for new injuries. Take other medicines such as ibuprofen or naproxen for the first 2 or 3 days after an injury.

NSAIDs should be taken exactly as prescribed or according to the label. Taking a larger dose or taking the medicine longer than recommended can increase the risk of dangerous side effects.

Talk to your doctor about whether NSAIDs are right for you. People who are older than 65 or who have existing heart, stomach, kidney, liver, or intestinal disease are at higher risk for problems. For other people, the benefits may outweigh the risks.

Aspirin should not be given to anyone younger than 20 because of the risk of Reye syndrome, a rare but serious disease.

By

Healthwise Staff

Primary Medical Reviewer

William H. Blahd, Jr., MD, FACEP - Emergency Medicine

Specialist Medical Reviewer

Robert B. Keller, MD - Orthopedics

Last Revised

December 14, 2011

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