1; Table 2) Two-way (Stimulus, Group) analysis of variance of th

1; Table 2). Two-way (Stimulus, Group) analysis of variance of the extracted percent signal change in the right pars triangularis revealed a main effect of Stimulus (P

Control P = 0.001; Acheulean vs. Control P check details in the frontal cortices, including medial frontal cortex, the right pars orbitalis, left pars triangularis, bilateral pars opercularis, right anterior insula, left posterior middle frontal gyrus and left precentral gyrus, as well as left middle temporal gyrus and right inferior temporal gyrus. Rapamycin The minimum statistic conjunction

between the three groups for the contrast Acheulean–Oldowan identified increases in activity in the anterior part of the left intraparietal sulcus (Fig. 3; Table 3), and in the left prefrontal cortex within the inferior frontal sulcus. In agreement with SPM whole-brain investigation, analysis of Guanylate cyclase 2C variance of activity extracted in these clusters indicated a main effect of the stimulus (both P 0.3) in these regions. Activity in Acheulean was significantly increased compared with Oldowan