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This is the peer reviewed version of the following article:Black, C., Tagiyeva-Milne, N., Helms, P., and Moir, D. (2015) Pharmacovigilance in children: detecting adverse drug reactions in routine electronic healthcare records. A systematic review. Br J Clin Pharmacol, 80: 844–854., which has been published in final form at 10.1111/bcp.12645. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.