Ana left SNL in 2002, and since then has appeared in various television programs and films, including Mean Girls. She can also be seen as a customer in the famous "Soup Nazi" episode of Seinfeld, well before she secured her SNL gig.

Most recently, Gasteyer starred as Elphaba, the Wicked Witch of the West, in the musical Wicked at the Oriental Theater in Chicago.

Currently, Gasteyer is starring in a revival of The Threepenny Opera on Broadway as Mrs. Peachum, along with Jim Dale, Alan Cumming, and Cyndi Lauper.

She and her husband, Charlie McKittrick, have a daughter, Frances (with whom she was famously pregnant during her last season on SNL).