Current Research and Scholarly Interests
Our research is aimed at defining the pathways of p53-mediated apoptosis and tumor suppression, using a combination of biochemical, cell biological, and mouse genetic approaches. Our strategy is to start by generating hypotheses about p53 mechanisms of action using primary mouse embryo fibroblasts (MEFs), and then to test them using gene targeting technology in the mouse.

Current Research and Scholarly Interests
I specialize in the treatment of gastrointestinal malignancies. I am interested in developing stereotactic body radiotherapy for tumors of the liver, both primary and metastatic. I am interested in developing functional imaging as a means of determining treatment response with radiation. I am also interested in developing image-guided radiotherapy to improve radiation delivery for GI cancers to reduce toxicity and improve disease outcome.

Current Research and Scholarly Interests
My laboratory focuses on two main areas: 1) cancer stem cell biology and 2) novel biomarkers for identifying the presence of malignant cells (diagnostic), predicting outcome (prognostic), and predicting response to therapy (predictive). Areas of study include cancers of the lung, breast, and gastrointestinal system. Clinically I specialize in the treatment of lung cancer and applications of stereotactic ablative radiotherapy and perform both prospective and retrospective clinical studies.

Current Research and Scholarly Interests
During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically.

Current Research and Scholarly Interests
Dr. Gibbs is a board-certified radiation oncologist who specializes in the treatment of CNS tumors. Her research focuses on developing new radiation techniques to manage brain and spinal tumors in adults and children. Dr. Gibbs has gained worldwide acclaim for her expertise in Cyberknife robotic radiosurgery.

Current Research and Scholarly Interests
Applications of molecular imaging in radiation therapy, development of hypoxia and radiosensitivity imaging techniques, small animal image-guided conformal radiotherapy, image processing and analysis.

Current Research and Scholarly Interests
Outcomes of radiation treatment for prostate cancer. Clinical research interests in the late effects of radiation on normal tissues and chemical modification of radiation injury. Hodgkins's disease and late effects of radiation and combined modality therapy. Radiation sensitizers. Hypoxic cell cytotoxins. Esophageal cancers.General adult and pediatric radiation therapy.

Bio
Dr. Wendy Hara specializes in the treatment of head and neck and skin cancers. Dr. Hara has a special interest in intraoperative radiation therapy (IORT) and Stereotactic Body Radiation Therapy (SBRT).

Current Research and Scholarly Interests
Development and integration of X-ray, MRI and US imaging technologies for radiation therapy guidance; Design of synergistic approaches to radiation therapy delivery; Treatment planning optimization and modeling.

Current Research and Scholarly Interests
Current research interests are inter- and intra- fractional motion, focusing on SBRT and realtime imaging. I have also recently been looking at quality assurance for gated VMAT delivery

Bio
Tae Jin Kim completed his Ph.D. degree in Mechanical Engineering from the University of Texas at Austin in 2013 (PI: Prof. Carlos H. Hidrovo). His dissertation research was on hydrodynamic and thermal characterization of superhydrophobic surfaces in microchannels with the aid of precision sensors and imaging fluorescent signals. He has served as a short-term postdoc at the University of Texas at Austin and Northeastern University under Prof. Hidrovo's supervision and has recently joined Dr. Guillem Pratx's laboratory in the Radiation Oncology department. His current work is focused in imaging emission of radiotracers in microchannels in the small scale and emission of Cherenkov radiation (radionuclide decay on surfaces).

Current Research and Scholarly Interests
Our interests include 1) study of the effect of radiation on regulatory cell subpopulations and co-stimulatory molecules, 2) use of radiation as an immune modulator for optimization of transplant regimens, 3) the role of radiation in tumor vaccine strategies, 4) study of new radiosensitizers and radioprotectors, and 5) discovery of new targeted therapies for the treatment of solid tumors.

Current Research and Scholarly Interests
The focus of my laboratory is to understand the role of hypoxia and the tumor microenvironment on malignant progression. My clinical area of interest is in the application of chemoradiotherapy and stereotactic body radiotherapy (SBRT) for GI malignancies.

Current Research and Scholarly Interests
My laboratory research interest focuses on the identification of biomarkers for prognosis in patients with head & neck or lung cancers. I am also conducting a number of clinical trials specifically in patients with head & neck cancers.

Current Research and Scholarly Interests
My current research is mainly focused on 3 areas: 1) quantitative imaging biomarkers for prognosis and early prediction of response to cancer therapy; 2) MRI-based radiation therapy treatment planning; and 3), image guided and adaptive radiation therapy.

Current Research and Scholarly Interests
1. Mathematical modeling of damage to tumors and normal tissues from irradiation.2. Image-guided intensity-modulated radiotherapy.3. Modeling the combined radiobiological effect of brachytherapy and external beam irradiation.4. Development of clinical hypofractionated extracranial radiosurgery.

Current Research and Scholarly Interests
My research interests focus on the design and discovery of synthetic, and natural product inspired small molecules which can be used as probes for developing understanding of biological phenomena, including protein-protein interactions and modulation of signal transduction pathways. My laboratory employs the tools of synthetic medicinal chemistry, molecular modeling and chemical biology for translational research in drug discovery, development, imaging and radiation.

Current Research and Scholarly Interests
My personal vision is the development of advanced, curative radiation therapy for all types and stages of malignancies, and new indications such as cardiovascular illnesses that will lead to increased survival worldwide from the top cancer and non-cancer causes of mortality.

Bio
Stav is a Physicist in training (B.Sc. in Physics with Medical Applications) with expertise in radiation detection (M.Sc. in Radiometrics: Instrumentation and Modelling) and radiation biology (M.Sc. in Radiation Biology). He joined the Graves lab after completing his Ph.D. in Radiation Biology at the University of Oxford, at the Experimental Neuroimaging Group. During his work at Oxford he focused on the development of novel molecular contrast agents for in vivo imaging methods, aiming to monitor angiogenesis in solid tumours or early detection of pulmonary micrometastasis. During his research at Stanford, Stav aims to expand his expertise in Radiation Therapy and more specifically on the effect of radiation on the tumour microenvironment and tumour cell migration.

Bio
Lynn Million specializes in the treatment of cancer. She has practiced Radiation Oncology for more than 30 years. Dr. Million has a special interest in the treatment of sarcoma’s of soft tissue, bone and cartilage in children, young adolescents and adults.

Current Research and Scholarly Interests
My research interests center around three areas of medical physics: radionuclide imaging, X-ray molecular imaging and high-performance medical computing. My research efforts aim to advance cancer care by integrating new imaging techniques into the clinical workflow, and further our basic understanding of cancer biology by designing new assays that can probe subtle biochemical processes in single cells.

Bio
Dr. Schüler is a medical physicist currently doing a postdoc at the department of Radiation Oncology at Stanford University.

His personal areas of emphasis are in the fields of radiation biology and physics, and he did his Ph.D. in the study of the biological effects of normal tissue following radiopharmaceutical administration. From his Ph.D. studies, Dr. Schüler acquired a special interest for peptide receptor radionuclide therapy and immunotherapy, as well as for molecular imaging techniques, and has since then also developed a specific interest in the challenging issues of more effective cancer treatments through novel treatment modalities and techniques.

He is currently working within the PHASER project, a large multicenter project involving Stanford University, Stanford hospital, and SLAC, with the goal of developing a radically new medical linear accelerator design, based on very high-energy electron beams that can be steered electromagnetically to deliver extremely rapid and highly conformal radiation therapy in a compact and affordable design compared to other particle therapy technologies.

Dr. Schüler received his Master’s of Science and Ph.D. from the University of Gothenburg, Sweden. He is a licensed Medical Physicist by the Swedish National Board of Health. He is currently a Postdoc at the department of Radiation Oncology at Stanford University.

Bio
Dr. Sengupta completed her PhD from Stanford University's Department of Chemistry in 2012, where she studied protein-based biomaterials for muscle tissue engineering applications. Thereafter, she completed a short bioengineering postdoc at UC Berkeley, where she studied vascular stem cell differentiation. She is currently a postdoctoral scholar at Stanford University’s School of Medicine in the Radiation Oncology department. Her current research is focused on the characterization of breast cancer cells using radioluminescence microscopy.

Current Research and Scholarly Interests
The photochemistry and radiation chemistry of DNA, the genetic control and biochemical bases of the multiple pathways of DNA repair, and the roles of DNA repair processes in radiation and spontaneous mutagenesis. Over 190 papers have been published on these and related topics.

Current Research and Scholarly Interests
My clinical and research interests focus on the development of new radiation techniques involving stereotactic radiosurgery and radiotherapy for the treatment of malignant and benign tumors of the brain and spine, as well as functional disorders such as trigeminal neuralgia.