Have you tried using the Forum Search option? Searching for libclntsh.so.10.1 will get you a lot of useful posts, [this one|http://forums.oracle.com/forums/thread.jspa?threadID=845201&tstart=0&messageID=3337566#3337566] is a sample.

OK let's start again with all you need to do as you don't clarify if you have done it or not:

1) Make sure you got a full Oracle 10g client installed (check with your DBA).
2) Make sure your Oracle 10g client has the OCI 32bits libraries installed (check in the ORACLE_HOME/lib32 directory that the libclntsh.so.10.1 library exists and it's size is bigger than 0 bytes).
3) Configure your OBIEE user.sh file to make sure your ORACLE_HOME and TNS_ADMIN variables are correctly set. You also need to set these two: