In New York after college, Bobby moves in with Jonathan and his roommate, Clare, a veteran of the city's erotic wars. Bobby and Clare fall in love, scuttling the plans of Jonathan, who is gay, to father Clare's child. Then, when Clare and Bobby have a baby, the three move to a small house upstate to raise "their" child together and create a new kind of family.

Calliope's friendship with a classmate and her sense of identity are compromised by the adolescent discovery that she is a hermaphrodite, a situation with roots in her grandparents' desperate struggle for survival in the 1920s.