As second-generation sequencing platforms have matured, all three major high-throughput sequencing systems — Illumina's Genome Analyzer, Life Technologies' ABI SOLiD, and Roche's 454 GS FLX — have entered labs across the world, according to a recent survey by In Sequence.

Although two-thirds of the 50 labs polled in the survey own only a single type of next-gen sequencing platform, a number of centers have started to mix and match systems from different vendors.

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