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Mizuho Kusanagi (Nee Kazami), a 23 (as alien physiology is only hinted at, and growth rates may be different for the un-named alien species she is partly derived from) year old half alien, half human, Class C Planet Inspector from the Galactic Federation, sent to delta DES 8228 (Earth) to observe and study humans. Mizuho came to Earth to monitor the planet, but was inadvertently seen by Kei Kusanagi as she was just landing on Earth. Although she did not trust him at first, she started to become attracted to Kei and eventually falls in love with him after they shared secrets about their past to one another. In a conversation with Maho, Kei learns that she is the youngest member of the GF Observers ever to gain a license. She is stripped of her surveyor status in episode twelve. Also from Maho, we learn that Mizuho apparently has never had a romantic relationship, which is verified when she admits as much to Kei. Her first and only romantic relationship is with Kei as he is her first and true love. She gave him her first kiss and chastity, and copulates with Kei every night.

Mizuho Kazami is an half alien half human. she has hot pink hair and purple eyes. Her height is 170 cm and she is 23 year old.Mizuho is a very beautiful,hot &sexy girl. She is a calm,nice and good behaviored girl. She is a teacher in Kei's school,in school she is seemed as Kei's teacher but back at home Mizuho and Kei are actually married. But they keep this a secret from the other school teachers,students and Kei's friends only it is seemed at some ending episodes that Ichigo and Koishi gotted to know about Kei liking thier teacher(Mizuho Kazami).

One of the main conflicts in the story involves Mizuho and how she tends to have great jealousy and misjudgment. She even went to great lengths to spy on Kei while he was hanging out with a friend from school, Koishi Herikawa, in a date set up by Ichigo Morino. Also, when Mizuho's mother held Kei hostage in a hotel.

She loves eating pochy, a Japanese snack food that consists of a biscuit stick covered with chocolate. She eats Pochy because it reminds her of her dead father; an empty box of Pochy was all Mizuho has left of him. Her mother and sister are also seen eating it in several episodes. Pochy is a fictional version of an actual snack known as pocky. Her catch phrase is "Saiyūsen jikō yo!" ("This is a priority one!").