Benthic and planktic foraminifera oxygen and carbon stable isotope measurements from four North Atlantic deep sea drill sites from the late Eocene to early Oligocene climate transition. The dataset contains new and existing data and metadata for ODP Site 647, DSDP Site 112, IODP Site U1411 and DSDP Site 612. Mg/Ca data and bottom water temperature reconstructions are included for Southern Labrador Sea Site 647.