After back-to-back successful seasons in 1996–97, Sehorn suffered a debilitating knee injury, tearing his anterior cruciate and medial collateral ligaments while returning the opening kickoff in a 1998 preseason game against the New York Jets.[5] Though Sehorn returned the next season, his speed was diminished. Still, he started 73 games for the Giants at cornerback in six seasons played from 1996–2002.

The Giants released Sehorn on March 7, 2003, and in May of that year he signed with the St. Louis Rams as a safety.[6][7] He missed the first six games of the season with a broken foot, but played in the last ten. The next year, his contract with the Rams was terminated after he failed a physical examination before the start of the 2004 season.[8]

Sehorn was signed by the Chicago Cubs after just one season of playing American Legion Baseball following his senior year of high school. An outfielder, Sehorn failed to produce as a hitter, batting just .184 in 49 games in 1990 for the rookie league Huntington Cubs.[citation needed]

Sehorn is now the Director of Communications at Sonic Automotive, an automotive retailer in the United States. As of March 19, 2009, the Company operated 164 dealership franchises at 135 dealership locations, representing 33 different brands of cars and light trucks, and 31 collision repair centers in 15 states.[citation needed]

Sehorn is also a college football analyst for ESPNU. He joined the network in 2011 as the in-studio analyst for Thursday and Saturday night games on ESPNU.[citation needed]

Sehorn was married to former CNN correspondent Whitney Casey.[9] His marriage to actress Angie Harmon is well known due to his unusual and public proposal. During one of Harmon's appearances on The Tonight Show with Jay Leno, Sehorn (with the assistance of host Jay Leno)[10] hid backstage and surprised Harmon by getting on one knee and asking for her hand in marriage in front of a live studio audience and millions more watching on television. They married in 2001 and have three daughters: Finley Faith, born October 2003, Avery Grace, born June 2005, and Emery Hope, born December 2008.[11] Both publicly support the Republican party.[12] The couple announced in November 2014 that they were separating after 13 years of marriage,[13] and divorced in December 2015. Sehorn married Meghann Gunderman January 2017.

Sehorn played a firefighter for one episode on the NBC show, Third Watch, in which his character is killed in a warehouse blaze.

On January 19, 1999, Sehorn's high school jersey #1 was retired by his alma mater, Mount Shasta High School, in a ceremony hosted by his longtime friend, mentor, and former coach, Joe Blevins. The ceremony aired on local cable television.[14]

In 2005, Sehorn joined Fox Sports Net, where he was a panelist on their Sunday NFL pregame show.[15]

Sehorn participated in ABC'sSuperstars competition during the NFL offseason. As a testament to his athleticism, he won the competition three consecutive years from 1998 to 2000.[16]