Research

Research within MCT: Personalised diagnostics and therapeutics

Research in MCT focuses on understanding the molecular basis of disease in order to develop and apply our findings to the identification of biomarkers and drug targets. Our aim is to improve our understanding of disease, so as to aid diagnosis, treatment and, ultimately, prevention. Using our state-of-the-art facilities and innovative approaches, clinician-scientist teams within MCT are leading therapeutic and biomarker discovery in the areas of autoimmune and inflammatory disease, cancer, cardiovascular disease, infection, platelet biology and neurological and psychiatric disease. We have close ties with a number of clinical facilities throughout Ireland, including RCSI teaching hospitals and both national and international centres. We also have access to the Clinical Research Centre at Beaumont Hospital, which has state-of-the-art facilities, expertise and equipment to advance patient-orientated research and clinical trials.

For more information regarding our research activities please use the appropriate link for each member of academic staff and under each research areas.

Infection is one of the major causes of morbidity and mortality. Antibiotic resistance is on the rise and novel anti-parasitic and anti-virals are needed to treat many infections. The immune response to the variety of pathogens is complex and can break down or autoactivate leading to pathogenic conditions.

Pharmacogenomics is the study of human genetic variation in the context of inter-individual variation in drug response. The overall aim of this research is to personalise medicine by identifying genetic variants that are clinically significant in predicting how a patient responds to drug treatment.