It’s a familiar sight to NFL fans. Drew Brees snapping off passes with precision. Saints catching the ball in stride. Saints celebrating touchdowns in the Superdome.

How the Chargers hold up against Brees could decide who celebrates last on Sunday night.

“No one else has really got him stopped,” said Chargers cornerback Quentin Jammer.

Brees is one of the NFL’s most accurate passers; on the TV show “Sports Science,” his passes thrown at game velocity rivaled Olympic archers for accuracy.

The Saints have two playmakers who put defenses on edge: Tight end Jimmy Graham, 6-foot-7 and 265 pounds, is able to pluck passes above defensive backs and outrun most linebackers assigned to him; and scatback Darren Sproles, who reaches top speed in a matter of steps.

Make no mistake: The Brees-led Saints attack, which leads the NFL in passing yards, is more capable than the aerial shows the Chargers defended in victories over the Raiders, Chiefs and Titans.

But the Saints aren’t as sharp as they used to be. Brees ranks 19th in passer rating (86.1) and 24th in completion percentage (57.6). He’ll be without one of his favorite receivers, Lance Moore (hamstring).

In pass defense, the Chargers are 18th in yards allowed and 16th in yards per attempts. The San Diego defense is 28th in sacks per pass play. In third-down efficiency, one year after finishing last the Chargers are tied for 18th.

The Chargers are healthy across their starting defense. With the Saints in mind, they signed veteran cornerback Chris Carr as an emergency fill-in. Backup corner Shareece Wright is out with an ankle sprain.

Expect the Chargers to lean toward conservative in their pass coverage, in the expectation that their front seven can limit the rush and pressure Brees. “You’ve just got to make sure you keep everything in front of you, and don’t let them get behind you, because big plays are the ones that kill you, 40- and 50-yard chunks,” Jammer said. “That’s the thing that you can’t let happen.”