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Uses

Principal Proposed Natural Treatments

Leukoplakia is a disorder of the mucous membranes. Symptoms consist of white, grey or red patches that form on the tongue, inside of the mouth, or, more rarely, the female vulva. These patches are thick, slightly raised, and often present a hardened surface. Areas of leukoplakia may be sensitive to touch, heat or spicy foods.

The cause of leukoplakia is not clear, but it often develops in response to chronic irritation, such as rough surfaces on dentures, fillings or crowns. One special type, known as hairy leukoplakia, involves a viral infection; it is found only in people who are HIV-positive.

Leukoplakia is associated with an increased risk of cancer in the affected area. Removing an identifiable irritant may resolve the problem. In some cases, surgical treatment is advised.

Principal Proposed Natural Treatments

Vitamin A
is known to play a role in the health of skin and mucous membranes. For this reason, vitamin A, used orally or topically, has been tried for leukoplakia. Unfortunately, no clear benefits have been seen. However, the related substance
lycopene
might be helpful.

In this
double-blind, placebo-controlled study
, 58 patients people with oral leukoplakia received either 8 mg oral lycopene daily, 4 mg daily, or placebo capsules for three months.
1,2
Participants were then followed for an additional two months. The results indicated that lycopene in either dose was more effective than placebo for reducing signs and symptoms of leukoplakia, and that 8 mg daily was more effective than 4 mg.

While one study cannot prove a treatment effective, these findings are definitely promising. For more information, including dosage and safety issues, see the
full lycopene article
.

Revision Information

This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.