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The ABCD Study is a national longitudinal study that will assess the short- and long-term impact of substance use on brain development. The project will recruit 10,000 youths before they begin using alcohol, marijuana, tobacco and other drugs, and follow them over 10 years into early adulthood.

ABCD Study investigators will use advanced brain imaging as well as psychological and behavioral research tools to evaluate brain structure and function. The study will track substance use, academic achievement, IQ, cognitive skills and mental health over time.