Ten physics problems for the next millenium from the Strings 2000 ConferenceAre all the (measurable) dimensionless paramters that characterize the physical universe calculable in principle or are some merely determined by historical or quantum mechanical accident and uncalculable?How can quantum gravity help explain the origin of the universe?What is the lifetime of the proton and how do we understand it?Is nature supersymmetric and if so, how is supersymmetry broken?Why does the universe appear to have one time and three space dimensions?Why does the cosmological constant have the value that it has, is it zero and is it really constant?What are the fundamental degrees of freedom of M-theory (the theory whose low-energy limit is eleven-dimensional supergravity and which subsumes the five consistent superstring theories) and does the theory describe nature?What is the resolution of the black hole information paradox?What physics explains the disparity between the gravitational scale and the typical mass scale of the elementary particles?Can we quantitatively understand quark and gluon confinement in quantum chromodynamics and the existence of a mass gap?

Problems: construct a quantum theory of gravity from some basic principles assuming noncommutative geometry (John Madore, ...) or express some sector or limit of an underlying theory in terms of the language of noncommutative geometry