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Santarus, Inc. (NASDAQ:SNTS) jumped 9.65% to $3.07 with over 1.80 million shares after it reported Wednesday it met the primary goal of a late-stage trial of its treatment for a type of inflammatory bowel disease, which it said was a major step toward applying for Food & Drug Administration approval.

Santarus, Inc. (Santarus) is a specialty biopharmaceutical company focused on acquiring, developing and commercializing products that address the needs of patients treated by gastroenterologists, endocrinologists and other physicians.

SYNNEX Corporation (NYSE:SNX) climbed 8.50% to $28.09 with over 422K shares after its fiscal third-quarter profit climbed 38% on higher broad-based demand and better margins, as the information-technology distributor's results easily topped its expectations. The company also issued a strong profit target for the current quarter.

SYNNEX Corporation (SYNNEX) is a business process services company, serving resellers, retailers and original equipment manufacturers (OEMs) worldwide. It operates in two segments: distribution services and global business services (GBS). The Company provides services in distribution, contract assembly and business process outsourcing services (BPO).

YRC Worldwide Inc. (NASDAQ:YRCW) slumped 21.20% to $0.253 after late Wednesday it has reached a tentative agreement with the International Brotherhood of Teamsters. This agreement would help the struggling company save $350 million a year through March 2015 and improve its competitive position. The company is expecting that all these processes will be completed by late October 2010.

The tentative agreement would extend by two years, 2013 to 2015 and provide a further 15 percent wage reduction, benefit and work rule changes. Under this agreement, the temporary cessation of the payment of pension contributions to the multi-employer pension funds would continue until June 1, 2011, and during that time, YRC Worldwide will contribute 25 percent of the contribution rate in effect on July 1, 2009.

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