Pheochromocytoma Diagnosis (Off-label)

Dosing Considerations

Extended-release is not to be used interchangeably with immediate-release tablets

Conversion from oral to transdermal

Day 1: Place Catapress-TTS-1; administer 100% of oral dose

Day 2: Administer 50% of oral dose

Day 3: Administer 25% of oral dose

Day 4: Patch remains, no further oral supplement needed

Cancer pain

Dilute 500 mcg/mL to 100 mcg/mL with 0.9% NaCl before administration

Epidural infusion considered as adjunct to intraspinal opiate therapy; epidural administration (Duraclon) is indicated in combination with opiates for the treatment of severe pain in patients with cancer not adequately relieved by opioid analgesics alone

More likely to be effective in patients with neuropathic pain than in those with somatic or visceral pain