Plakson also had a recurring guest role on Mad About You as Dr. Joan Golfinos, the partner of Paul's sister Debbie (another regular guest star on the series was Anne Ramsay, who appeared in the same episode, "The Emissary", with Plakson; Gates McFadden also made several guest-appearances on the show). More recently she's appeared in a recurring role as Marshall's mother on How I Met Your Mother.