In this study, detailed diffusion measurements of pediatric
glioma using multiple b-factors ranging up to 4000 s/mm2 have been made. 17
children with brain tumors underwent brain MR examinations at 3T scanner.
Results showed that the biexponential and stretched-exponential model can all
meet the WHO classification of the pediatric gliomas in the brain more
accurately than the standard ADC. Multi-exponential diffusion decay functions
are required for diffusion signal decay curves when sampled over an extended
b-factor range, providing additional, unique tissue characterization
parameters for pediatric gliomas in the brain.