We heard hints of this project at the New York Comic-Con and we know that Cable is squaring off against the Avengers in January. But starting in March 2012, Avengers Vs. X-Men — a 12-issue, biweekly series written by Brian Michael Bendis, Jason Aaron, Ed Brubaker, Jonathan Hickman, and Matt Fraction — will see Marvel's two bigger superteams butt heads. John Romita Jr., Olivier Coipel, and Adam Kubert will be on art chores.

The New York Comic Con is a frothing bouillabaisse overflowing with panels and pageantry. Here are…
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Of course, many X-Men are Avengers (and vice versa), so some people are going to lose their membership privileges to Tony Stark's walk-in humidor. From the synopsis in today's, uh, USA Today:

Kicking off in a special "zero issue" prologue in March written by Bendis and Aaron, Avengers vs. X-Men begins the next month with an extinction-level event barreling its way toward Earth, namely the cosmic entity of death and rebirth known as the Phoenix Force. It's looking for a new host who will possess all of its power, which may or may not be the mutant teenager Hope Summers.

Cyclops, Wolverine, Magneto and the other X-Men want to protect her and prepare her if she's to be the new Phoenix. Captain America, Iron Man, Spider-Man and their fellow Avengers want her handed over to them so they can figure out what to do with her and keep the world safe from a potentially fiery fate.