She introduced the pessary (diaphragm) to the Netherlands despite intense opposition from male colleagues, held a free clinic for poor women two mornings a week, and campaigned to change the unhealthy working conditions of salesgirls.

'One of his targets was Margaret Sanger, a nurse who wrote a sex education column, “What Every Girl Should Know,” for a left-wing New York newspaper, The Call. When Comstock banned her column on venereal disease, the paper ran an empty space with the title: “What Every Girl Should Know: Nothing, by Order of the U.S. Post Office.”'