"The 6490 QQQ is a quite easy to use the instrument. I first started with zero experience on QQQ but got comfortable with this instrument after very short period of training. The data we obtained are easy to analyze either with the manufactural software or Skyline. We did once have issues with the calibration and low sensitivity right after PM (not sure what happened, but a service engineer came to fix/replace some parts and since then the instrument is behaving great."

"Agilent offers brilliant packages for service contracts for Mass Spectrometry. We have two Agilent Mass Specs in our lab and have taken the silver contract with them. The response time for a logged call is 48 hours and there is hardly any time where they delayed in getting back to us. Their field scientist are well trained and know what they are doing. I have learnt a lot while they are on call at our facility. I would definitely recommend the equipment and service contracts from them. They also offer cross lab service contracts."

"The 6490 mass spectrometer has standard MS/MS scan capabilities, but is really designed and intended for a novice user. Many features for the operation of the instrument are automated, which is perhaps good for an inexperienced user. However, a mass spectrometrist is limited by what the software will allow. For example, tuning, resolution adjustment, and calibration are relatively restricted to automated procedures, rather than allowing the operator to adjust and set the instrument as desired. Sensitivity of the instrument is average or below, compared to other triple-quad instruments on the market, particularly negative-ion experiments. The instrument also has somewhat unstable ionization."

"Utilizing our new improved method, we have reach a highly sensitive way of analyzing low levels of metaldehyde within water. Using the Agilent 6400 LC/MS QQQ this has been accomplished, only problems which have occurred is with the maintenance as this can become problematic when organizing availability of engineers "

"The Instrument was purchased about 2 years ago, at this time it showed best sensitivity for nucleoside detection if compared to to triple Q models of Thermo, Waters, or Absciex at this time ( LOD ~20 fmols). We are a scientific group but have ran the instrument day and night since the purchase. It runs with minor technical problems, some can be solved by us, some require parts replacement and done by the service engineer one or two days after the call. It maintains the calibration over weeks or even months, requiring minor attention for cleaning and re-calibration. In general Agilent instruments are very well engineered and manufactured and this is instrument is one of such examples. We are very satisfied with its performance."

"It is a very robust instrument with high sensitivity, it has not totally proven it self in the Residue chemistry area but I think it has a lot of potential to be one of the best. The software needs some work but the Mass hunter has put Agilent with the best. It is easy to clean and maintain. One negative is that sometimes you have some variability between sample injections but it is compound dependent. I recommend this instrument for Environmental analysis, and some residue studies."