Translational Genomics & Bioinformatics Group , GBRC

Delivering Quality Research

For developing a centre-of-excellence in Translational Genomics & Bioinformatics

Tackling societal problems

Through multiomics and systems biology

Developing skilled human resources

For cutting-edge research in Bioinformatics and computational biology

RESEARCH PROGRAMS

Development of Potential RNA based Therapeutic Agents

MicroRNAs (miRNAs) targeting pathways of human disease provide a new and potential powerful candidate for therapeutic intervention against various diseases. Our group is trying to decipher the mechanism of action, the ability to function as master regulators of the genome and an apparent lack of adverse events in normal tissue,which make microRNA a promising technology for current and future therapeutic development. Ineterestingly, we are involved in using this tiny riboswitches as a targeted immunomodulators for various discorders

Development of DNA based Diagnostics for important societal health problem

Understanding the disease architecture and possible multiomics and systems biology interventions towards the discovery of new molecular targets for effective vaccine candidates. Our group is trying to develop a complete cascade of information on diseases like leptospirosis, MDR and various Cancers and make an attempt to understand the metadata of genomes, epigenomes and proteomes towards host-pathogen relationship & molecular pathways involved, which may translate into valuable products for the society.

Currently, Biotechnology and Life sciences sector is completely dependent on the Bioinformatics as a major driver. There is a huge demand of need-based tool/software/pipeline/database for each type of biological data analysis and contributes major market as well. It will help to facilitate processing, analysis, and management of large data sets for human welfare. Our group is trying to look into the Big Data of bioresources and analyse extensively in all levels of genomics, metabolomics and proteomics for valuable enzymes, genes, proteins and metabolites which may use for various industrial and environmental applications.

Marine Biotechnology Unit

Marine biotechnology research can unlock the potential of the marine environment’s biodiversity; leading to new knowledge, improved industrial competitiveness and supporting India’s economic growth. Currently, Marine biotechnology unit investigate the novel biomarkes for the development of Diagnostic kit for Alzhimer disease towards developing therapeutic targets for AD. Our group is also doing research on marine genomics with special emphasis on Metagenomic studies of mangroves rhizospheric soil and Coral whole genome sequencing.

Opportunities

We value your research Interest in collaborating with us and welcome any opportunities to explore the possibilities of working with you. Please feel free to drop an Interest for joint program/bilateral projects/postdoc to jd2-gbrc[at]gujarat[dot]gov[dot]in

SERB/DST/DBT/CSIR/ICMR young scientists and Post doctoral researchers are encouraged to apply for joining the group through a funding agency

TRAINING & WORKSHOP

We provide hands-on-trainning to faculties in the areas of Genomics, Transcriptomics, systems biology, Network biology, etc. from time to time. Also, we committed to produce highly skilled manpower for NGS data analysis, development of software/pipeline/database which will be useful for addressing biological problems. We provide training to all level of students and scholars including B.Sc., B.E., B.Tech., M.Sc., M.Tech., M.Phil., Ph.D and Postdoc. For training and dissertation keep visiting GSBTM website.