Despite the use of antimycotics as a treatment option, there are few studies reporting favorable results and do not show results with convincing evidence of the efficacy of the treatment in cutaneous granuloma due to pythiosis (7).

Within the first 30 minutes, they were taken to the laboratory in a transporting media which consisted of Dulbecco's Modified Eagle Medium (DMEM) (Biosera, South Africa), 10% Fetal Bovine Serum (FBS) (Biosera, South Africa), 1% antimycotic (PAA) and 1% gentamycine (PAA).

Due to the fact that chemotherapy protocols lead to subsequently longer periods of aplasia with different recommendations for antibiotic or antimycotic prophylaxis, we performed a subgroup analyses (Cheson et al.

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