The Centers for Disease Control and Prevention (CDC) recently released 2 infection prevention documents for clinicians in outpatient settings. The Guide to Infection Prevention for Outpatient Settings: Minimum Expectations for Safe Care highlights existing CDC and Healthcare Infection Control Practices Advisory Committee recommendations, summarizes basic infection prevention recommendations for outpatient (ambulatory care) settings, reaffirms standard precautions as the foundation for preventing transmission of infectious agents during patient care in all health care settings, and provides links to full guidelines and source documents. The Infection Prevention Checklist for Outpatient Settings: Minimum Expectations for Safe Care is a companion to the guide. Facilities can use it to ensure that they have established appropriate policies and procedures, have adequate supplies to allow health care personnel to provide safe care, and systematically assess personnel adherence to correct infection prevention practices.