Is it possible to automate the city queue? i.e. what buildings to build next (and stop pestering me with it, once I have given a general guideline). I seem to remember this feature from Civ4, where it did not work very well though.

3 Answers
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I don't think you can automate it, but you can certainly create a production queue from the city screen. Tick the Show Queue box and add items one by one. You then won't be pestered until the queue is empty.

Unfortunately no, there is no Civ3/4 style Governor feature. But, if you capture an enemy city you have the option to make it a "puppet" city, which basically means it uses a governor- the entire city screen is automated and unavailable to you- in exchange for lower unhappiness. However you can't do this to your own cities.