To avoid problems associated with colinearity, we performed a correlation analysis to identify pairs of predictor variables that had high colinearity ([absolute value of r] [greater than or equal to] 0.

The issues we have highlighted here--temporal relationships between stressors and pollution; nonlinearity and saturation effects; spatial colinearity across exposures; age-related susceptibility and critical periods; and distinctions between processes related to illness etiology and exacerbation--will be critical in exploring social--environmental interactions.

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