Abstract

A number of personal and environmental risk factors are known to gastrointestinal (GI) cancer development. Cancer syndromes are also responsible for increased incidence of same or different cancers in involved family members. However, only a few genetic abnormalities were known to cancer syndrome. We wonder whether family history of GI cancers in first relatives has relevance to an increased risk of any GI cancer or not. But there were few studies investigating the risk of family history of GI cancers for other GI cancers. The aim of this study was to evaluate the relationship between family history of GI cancers and incidence of any GI cancer in Korean populations.