The National Cancer Institute, Rockville, MD, USA has successfully
collected
many chemical samples. These samples are used for developing drugs
againast
cancer. A project of collecting all chemical samples for all purposes
of
bioactivity studies was launched by the international organization MDPI
[1] in Switzerland.

This has been supported by companies collecting chemical samples.
With
the development of high throughput screening technology in recent
years,
the acquisition of chemical samples by samples collection and
combinatorial
synthesis now become the bottleneck in the process of new drug
discovery.
The development of any pharmaceutical and agrochemical products and
reesarch
on any fields of life sciences require a large number of chemical
samples.

It is also important for preparative or synthetic chemists. Chemists
contribute not only new knowledge but also new substances. However,
more
than 90% of compounds recorded in literature exist only on paper; they
were discarded by chemists. We are now appreciating molecular
diversity.
The high quality of a chemical library relies on the distinct
differences
of both the structures and properties of the collected samples [2].
These
compounds in isolated form are traditionally and still routinely
prepared
in the laboratories and isolated from natural sources. Among other
strategies,
the first journal of organic chemistry and natural product chemistry,
Molecules
(visit http://www.mdpi.org/molecule/), was launched by MDPI in 1995 to
encourage authors to deposit their compound samples at MDPI center in
Switzerland
and distribute at reasonable prices worldwide. This example has been
followed
by six other chemistry journals so far (http://www.mdpi.org/forum.htm).
The idea [3,4] of this program is to supply both chemical information
as
well as the chemical substances themselves.

Acknowledgements: I would like to thank my colleagues Dr. Regis
Turin
and Dr. Amparo Zapata for their supports.