Insulin Receptors

On and in our body's cells, Insulin Receptor is a cell surface receptor for insulin, comprised of a tetramer of two alpha and two beta subunits, derived from a cleavage of a single precursor protein. In our body, Insulin Receptor contains an intrinsic tyrosine kinase domain located within the beta subunit, and activation of the receptor by insulin results in numerous metabolic changes including increased uptake of glucose into the liver, muscle, and adipose tissue. *

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