Background: The number of founding germ cells (FGCs) in mammals is of fundamental
significance to the fidelity of gene transmission between generations, but estimates from various methods vary widely. In this paper we ...

Drug resistant malaria was a major factor contributing to the failure of a worldwide campaign to eradicate malaria in the last century, and now threatens the large investment being made by the global community in the rollout ...

Intrinsic resistance of Plasmodium falciparum is clearly a major determinant of the clinical failure of antimalarial drugs. However, complex interactions between the host, the parasite and the drug
obscure the ability to ...

Molecular markers for drug resistant malaria represent public health tools of great but mostly unrealized potential value. A key reason for the failure of molecular resistance markers to live up to their potential is that ...

A World Antimalarial Resistance Network (WARN) database has the potential to improve the treatment of malaria,
through informing current drug selection and use and providing a prompt warning of when treatment policies need ...