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Abstract

There is a continuous search of new implant materials with better biocompatibility and
physiological properties than the current commercially pure Ti and Ti-6Al-4V alloys.
Gamma titanium aluminide (γTiAl) appears to have excellent potential for bone repair
and replacement. The response to γTiAl implant is expected to be similar or better than
those of Ti-6Al-4V. Human fetal osteoblast cells were cultured on the surface of γTiAl
and Ti-6Al-4V discs with variable surface roughness for both SEM and
immunofluorescent analysis to detect the presence of collagen type I and osteonectin,
proteins of the bone extracellular matrix. Results show that cell growth and attachment on
γTiAl was normal compared to that of Ti-6Al-4V, suggesting that γTiAl is not toxic to
osteoblasts. Normal growth and the presence of collagen type I and osteonectin was
observed on γTiAl and Ti-6Al-4V. The results obtained suggest γTiAl is biocompatible
with the osteoblasts.