With the world ending around them, Red Hood and Batgirl take shelter in the most unlikely place: an orphanage full of children! Will they be able to protect the kids from the impending hordes of the infected streaming out of Gotham City and Blüdhaven? And elsewhere, Deathstroke, Vandal Savage, and some of DC's worst villains battle the apocalypse out as an "Anti-Suicide Squad." But a certain wondrous woman may not let them have it their own way!