An efficient construction of a $C_{3}-symmetric$ macrocycle by head to tail cyclotrimerization of an unsymmetrical diene via a sequence of highly regio- and stereoselective metathesis reactions

Srikrishna, A and Dethe, Dattatraya H
(2005)
An efficient construction of a $C_{3}-symmetric$ macrocycle by head to tail cyclotrimerization of an unsymmetrical diene via a sequence of highly regio- and stereoselective metathesis reactions.
In: Tetrahedron Letters, 46
(19).
pp. 3381-3383.

Abstract

A sequence of highly regio- and stereoselective intermolecular metatheses followed by ring-closing metathesis of an1-allyl-3-(3-butenyl)cyclohexanol led to a $C_{3}-symmetric$ head to tailcyclic trimer; a 24-membered macrocycle containing three inward directed hydroxyl groups creating a hydrophilic cavity.