5) The Global Integrated ISR Command would develop doctrine and plans to enable "leaders to make informed decisions at a superior decision speed to help ensure freedom of action, maintain deterrence, contain crises, and achieve operational success" (emphasis in original).

Specifically it will be evaluated in: a)big biostreams where the decision speed is critical and needs non-linear and multi-parametric estimators for clinical decision support within limited time, b)big-data from non-malignant diseases where the need for NGS and molecular data analytics requires the combination of cloud located resources, coupled with local demands for data and visualization, and finally c)big-data from chronic diseases including EHRs and medication, with needs for quantified estimates of important clinical parameters, semantics extraction and regulatory issues for integrated care.

Part of learning to fly twins involves being coached about selecting a go/no-go decision speed, as well as how to safely abort a takeoff--in other words, thinking ahead about what you would do if things don't go according to plan.

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