WJPR Citation

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar. Best Paper Award : Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

GLYCEMIC CONTROL WITH DIFFERENT TYPES OF INSULIN IN THE MANAGEMENT OF GESTATIONAL DIABETES MELLITUS

Ambarisha Bhandiwad and *Surakshith L Gowda

ABSTRACT

Background: Gestational diabetes mellitus is one of the most common
medical complications of pregnancy. It has been demonstrated that
good metabolic control maintained throughout pregnancy can reduce
maternal and fetal complications in diabetes and insulin is considered
as gold standard for the management of GDM. Aim: To compare the
efficacy of regular insulin with rapid acting insulin in combination
with intermediate acting insulin in the management of GDM.
Methods: It is a retrospective review analysis of two groups of
patients, in whom one group of patients was started with regular
insulin and another group of patients on rapid acting insulin with one
dose of isophane insulin at bed time and results were compared in
terms of mean glucose values, neonatal birth weight, amniotic fluid index, period of gestation
and neonatal hypoglycemia. Results: The mean glucose value in rapid acting insulin group
was 108.2mg/dl whereas it was 116.4mg/dl with regular insulin group. The mean AFI and
period of gestation in rapid acting group was 10.6 cms and 38 weeks 5 days respectively in
comparison with 13 cms and 37 weeks 3 days for regular insulin group. 60% of the babies in
regular insulin group had neonatal hypoglycemia and it was 30% for rapid acting group.
Conclusion: It was found that rapid acting insulin along with isophane insulin (NPH) at bed
time had better glycemic control in comparison with only regular insulin.