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New work published in February 2010 shows that weak coupling between cellular oscillators can lead to rapid synchronization. With such a strong effect, there is often no need for cellular processes to be connected to any centralized or controlling clock.

Systems Biology, Networks and Robust Control

The research group in this area at the University of Leicester includes Pat Heslop-Harrison. There are many collaborators, including those who have now moved from Leicester to Deputy Vice Chancellorships, Professorships and Lectureships elsewhere between 2008 and 2010. Links to their current positions are given with the names.

The development of in silico molecular models of phamaceutically important signal transduction pathways that regulate intracellular processes involved in human diseases.

The development of models that are strictly formulated according to experimental data and biophysical principles, that reproduce experimental data, and that make new predictions that cannot be seen from experiments only.

The use of mathematical models as tools for preclinical and clinical drug development pipeline.