This research study was designed to test the safety and effectiveness of autologous stem cell graft in the myocardium of patients with refractory Congestive Heart Failure (CHF) with ischemic etiology. Cellular implantation will take place during off-pump revascularization surgery or during an ad hoc procedure using a mini-thoracotomy access.

History of malignant neoplasia in the 5-year period before the study (save for in-situ carcinoma of the cervix treated successfully and skin tumors – not melanomas)

Incapability or unwillingness to comply with the envisaged treatment protocol, follow-up, or tests.

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00480961

Locations

Italy

Ismett

Palermo, PA, Italy, 90127

Sponsors and Collaborators

The Mediterranean Institute for Transplantation and Advanced Specialized Therapies

Investigators

Principal Investigator:

CESARE SCARDULLA, md

The Mediterranean Institute for Transplantation and Advanced Specialized Therapies