Anything was fair game during Andy Cohen's chat with BuzzFeed executive vp Ze Frank and YouTube talents Tyler Oakley and Grace Helbig during their talk at SXSW in Austin.

Cohen, host of Watch What Happens Live rattled off a series of questions during the hour-long March 7 panel. Among them, how do Oakley and Helbig keep their fans engaged even as their audiences grow?

"I think the one-on-one interaction is important," responded Oakley, who has more than 4 million YouTube subscribers. "For me it's a two-way street. I want to hang out with them in the same way that they want to connect to me."

Helbig, creator and host of the It's Grace channel, added that it's a 24-hour job interacting with fans. She said she tells herself to "tweet two or three things a day. There are some days I don't do that and it's like I didn't do my job today."

They also loosened up and answered some fun questions from Cohen and the audience. Frank's favorite Internet cat? Lil' Bub. Helbig's favorite Twitter account? Tyra Banks. One of Oakley's favorite shows to binge watch? Veep.

The conversation ranged several topics, even touching on advice to up-and-coming YouTube creators. Helbig said each person should figure out what they want to do and stick with it. Oakley echoed that they should be consistent in their programming.

At one point Helbig and Oakley engaged in some lighthearted bickering, and Cohen joked, "This is like a Housewives reunion."