Description:
Health & longevity through the healing power of
nature-that's what it means to trust the leaf Ashwagandha Extract (Withania somnifera) is standardized to 2.5% withanolides. It has been traditionally used for it adaptogenic benefits.

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This scientific independent research is provided by Aisle7 and is for informational use only. GNC provides this information as a service but does not endorse it. Likewise, Aisle7 does not recommend or endorse any specific products.

For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Dose: 80 to 300 mg of standardized herbal extract two to three times per day with a doctor's supervision
Antioxidant hawthorn appears to reduce symptoms and improve exercise capacity by increasing blood flow to the heart and the strength of heart contractions, and reducing resistance to blood flow in the extremities.
(more)

Hypertension

Dose: 1,200 mg per day of an herbal extract standardized to 2.2% flavonoidsHawthorn leaf and flower extracts have been reported to have a mild blood pressure-lowering effect.
(more)

Angina

Dose: 60 mg of an herbal extract containing 18.75% oligomeric procyanidins taken three times per dayParts of the hawthorn tree contain flavonoids that may protect blood vessels from damage. Taking hawthorn extract improved heart function and exercise tolerance in angina patients in one trial.(more)

Dose: 160 to 900 mg daily of a standardized herbal extract with a doctor's supervision
Studies have found hawthorn to be effective for the signs and symptoms of early-stage congestive heart failure, the main complication of cardiomyopathy.(more)

Cardiac Arrhythmia

Dose: Refer to label instructionsHawthorn has been used traditionally to reduce the frequency of arrhythmias.(more)

Dose: 80 to 300 mg of standardized herbal extract two to three times per day with a doctor's supervision

Clinical trials have shown that standardized extracts made from the leaves and flowers of hawthorn are effective in helping people with early-stage CHF.1, 2, 3 Hawthorn extracts appear to increase blood flow to the heart, increase the strength of heart contractions, reduce resistance to blood flow in the extremities, and act as an antioxidant.4, 5, 6 In a large preliminary trial, people with mild to moderate CHF were given 300 mg of hawthorn flower and leaf extract (standardized to contain 2.2% flavonoids) three times a day for two months.7 Symptoms of CHF-including heart palpitations, chest pressure, and swelling in the extremities-decreased throughout the trial during the use of hawthorn. The efficacy of hawthorn for the treatment of CHF has been confirmed in a double-blind trial.8

Hawthorn extracts are available in capsules or tablets standardized to either total flavonoid content (usually 2.2%) or oligomeric procyanidins (usually 18.75%). Doctors who work with herbal medicine often suggest 80-300 mg two to three times per day. Hawthorn berry products that are not standardized may be weaker, and the recommended amount is typically 4 to 6 grams per day for the whole herb, or 4-5 ml of the tincture three times per day.

Dose: 1,200 mg per day of an herbal extract standardized to 2.2% flavonoids

Hawthorn leaf and flower extracts have been reported to have a mild blood pressure-lowering effect in people with early stage congestive heart failure.1 In a double-blind study, supplementation with a hawthorn extract significantly decreased diastolic blood pressure in people with type 2 diabetes. The amount used was 1,200 mg per day of an extract standardized to 2.2% flavonoids corresponding to 6 grams per day of dried flowering tops.2

Dose: 60 mg of an herbal extract containing 18.75% oligomeric procyanidins taken three times per day

The fruit, leaves, and flowers of the hawthorn tree contain flavonoids, including oligomeric procyanidins, which may protect blood vessels from damage. A 60 mg hawthorn extract containing 18.75% oligomeric procyanidins taken three times per day improved heart function and exercise tolerance in angina patients in a small clinical trial.1

Dose: 160 to 900 mg daily of a standardized herbal extract with a doctor's supervision

Many doctors expert in herbal medicine consider hawthorn to be an effective and low-risk therapy for congestive heart failure, the main complication of cardiomyopathy. Rigorous clinical trials have now confirmed the effectiveness of hawthorn for the signs and symptoms of early-stage congestive heart failure,1, 2, 3, 4, 5 though hawthorn studies with cardiomyopathy patients have yet to be conducted. The clinical trials with heart-failure patients have demonstrated efficacy using 80 to 300 mg of standardized extract of hawthorn leaves and flowers two to three times per day.

An animal study showed that an extract of hawthorn significantly reduced the number of experimentally induced arrhythmias.1 Although the use of hawthorn for arrhythmia in humans has not been studied scientifically, it traditionally has been used for this purpose.2

The information presented by Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2017.