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A new edition of a highly regarded text in the series on Pain Research and Clinical Management. The book is now used as a standard reference text for those working in the field of neonatology and paediatric pain assessment and management. It provides a comprehensive resource of the latest information in the field for use by both researchers and clinicians. The text is intended for use by all professionals working in the field: neonatologists; pediatricians; anestheiologists; nurses; psychologists.

Multidisciplinary editorship and authorship ensuring relevancy and balance of content for all professional groups concerned.

Clinically relevant and research based.

Edited and written by the best known international names in the field.

Covers pain management in infants up to 1 year of age as well as term and preterm neonates.

Includes new chapters on: Long-term consequences of neonatal pain from animal models; Pharmacogenetics and pharmacodynamics of analgesic drugs; Neuraxial and Regional Analgesia and Anesthesia; Fetal pain and surgery; Vulnerable Populations, Palliative Care; Infant Pain in the Home and Community, Developing Countries; Health Policy and Health Economics related to Infant Pain; Complementary and Alternative Approaches to Pain in Infancy; and Future Direction.

Overview of neonatal and infant pain

Development of peripheral and spinal nociceptive systems

Development of supraspinal pain processing

Long-term consequences of pain in human neonates

Long-term consequences of neonatal and infant pain from animal models. Assessment of pain in neonates and infants

Infant colic: clinical implications and current controversies

Pharmacogenetics and pharmacogenomics of analgesic drugs

Pharmacokinetics and pharmacodynamics of analgesic drugs

Evidence for systemic morphine and fentanyl analgesia

Central and peripheral regional analgesia and anesthesia

The social and environmental context in which pain is experienced in neonates. Pain and the human fetus