Overview

Special Offers

Key Specifications Table

Species Reactivity

Key Applications

Host

Format

Antibody Type

M

ELISA

R

Purified

Monoclonal Antibody

Description

Catalogue Number

ELI-018-M

Description

TNFα ELISPOT Antibody Pair, Mouse

Overview

Tumor Necrosis Factor alpha (TNFα) is a multifunctional proinflammatory cytokine that is secreted by activated macrophages, monocytes, neutrophils, T-cells, and NK cells, and is involved in the regulation of several biological processes including inflammatory responses, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. While under normal conditions, mouse TNFα expression has been shown to induce the destruction of tumor cells, the overproduction of this cytokine has also been implicated in autoimmune diseases, insulin resistance, and cancer, as well as the induction of cachexia and toxic shock. The Millipore mouse TNFα ELISPOT Antibody Pair provides a sensitive and highly reliable method for the detection of TNFα secreting cells at the single cell level.

Please refer to the Certificate of Analysis for the lot-specific concentration.

Host

Rat

Specificity

Both the capture and the detection antibodies included in this kit react with mouse tumor necrosis factor (TNFα).

Species Reactivity

Mouse

Antibody Type

Monoclonal Antibody

Molecular Weight

~17 kDa

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Usage Statement

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information

Storage Conditions

Maintain refrigerated at 2-8°C for up to six months from the date of receipt.