Studies show Capsaicin-based pain relievers are the way to go! Before you reach for IcyHot® or Bengay®, which use Methyl Salicylate as an active, consider this article (click on the link below). Not only is Methyl Salicylate less effective at relieving pain, but it can also cause an overdose when used excessively. It has the same lethal risks as aspirin. Capsaicin, on the other hand, is naturally derived, safe, effective, and proven to work better over time.