I want to update my wii 4.1e

I have my wii version is 4.1e and many channels i have installed from homebrew channel.
i want to know if i update my wii version to 4.3 or latest.. may come some problum or may brick my wii or may delete my all channels which i have in wii system momery..

or if not remove anything then before update my installed channel work in new version????????????

Please help!!
i want to update for enter in wii shop to download some channel so this what is have to do Thaks a Lot is Advance...