Description

DMRT3, also known as Doublesex and mab-3-related transcription factor 3, is a 51.2 kDa, 472 amino acid protein that is involved in arranging spinal circuits, developing neuronal specification in particular spinal cord neurons, and regulating transcription during sexual development. Diseases and disorders such as gonadoblastoma, Turner syndrome, sex reversal, Rokitansky-Kuster-Hauser syndrome, and squamous cell carcinoma have been studied with the protein. The protein interacts in transcription pathways.