Risks and Warnings for Rexulti (brexpiprazole)

Older patients with dementia-related psychosis have a higher risk of death when treated with antipsychotic medications. Rexulti (brexpiprazole) is not approved to treat dementia-related psychosis. Talk to your doctor if you have questions.

This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Rexulti (brexpiprazole) can increase your blood sugar and cholesterol and your weight. If you already have high blood sugar or cholesterol, talk to your doctor to see what you can do to stop it from getting worse.

Rexulti (brexpiprazole) does not cause as much weight gain as other similar medications.