Mortality & Cardiovascular Events: The Role of Maternal Obesity

Maternal Obesity during Pregnancy and Premature Mortality from Cardiovascular Event in Adult Offspring: Follow-up of 1,323,275 Person Years.

Study Question

Is maternal obesity associated with an increased risk of premature death and cardiovascular disease in adult offspring?

Summary Answer

Yes, maternal obesity is associated with an increased risk of both outcomes in offspring followed up to ages 36-62.

What is Known and What This Paper Adds

Adult offspring of women who were obese in pregnancy have increased cardiometabolic risk factors and increased risk of premature death and hospital admissions for cardiovascular events. Offspring of overweight women also have higher risk of adverse events in later life.

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