Oprah showed Pharrell a montage of people around the world who have uploaded their own happy-go-lucky dance videos to the tune of “Happy.” The moment moved Pharrell to tears.

“Why am I crying on Oprah?” Pharrell asked rhetorically.

But Pharrell isn’t the only celebrity who has been moved to tears after sharing a pivotal moment with the former queen of daytime talk. Watch the video below and check out our list of five other celebrities who have been moved to tears on Oprah.

1. Arsenio Hall tears up while talking about his son

2. 50 Cent tears up while talking about his mother

3. Madonna cries as a mother reads a letter about how much the singer affected her daughter’s life

4. Celine Dion cries just being in Oprah’s presence

5. Jennifer Aniston gets emotional while talking about the end of Friends

Which moment made you want to grab a Kleenex? Tell us about your favorite interview in the comments below.