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In traditional vaginal delivery used any intervention such as: IV line, prescription of oxytocin and episiotomy but in physiologic delivery did not do any intervention and exit of placenta was spontaneously and patient position in favorable situation. Comparing laceration and hemoglobin decrease in physiologic delivery and traditional vaginal delivery. Recent study are analytical epidemiologic study, case control that doing in 500 pregnant women who come to Kosar hospital with labor pain that randomly divided in two groups of traditional vaginal and physiologic delivery (250 cases in each group) and progress of delivery controlled then information an questionnaires completed. In recent study, in traditional vaginal delivery, 73.2% cases was used episiotomy. In physiologic group in 66.8% of cases there was not any laceration and 29.6% of cases grade I, 3.6% of cases laceration grade II. In traditional vaginal delivery in 26.8% of case there was not any episiotomy. That there was not laceration in 53.7%, 41.8% laceration grade I and 4.3% laceration grade II. The mean of Hb after 6 h of delivery in physiologic delivery was statically higher than traditional vaginal delivery (p<0.001). The findings show that the risk of laceration and decrease of Hb in physiologic delivery is less than traditional vaginal delivery. So, researchers can use physiologic delivery as routine.

This study was done in order to study the effect of IV injection of hyoscine upon delivery progression. This double blinded clinical trial study was done on 140 term, cephalic presentation pregnant women who have not natural vaginal delivery were admitted in Kosar hospital in autumn 1388 for pregnancy termination. A sample was selected based on inclusion and exclusion criteria and randomized divided into two groups, 20 mg (l mL) hyoscine was given to group one and l mL distilled water was given to control group (group 2). These IV injections were done as single dose at the beginning of active labor. After that duration of the 1st, 2nd and 3rd stages of labor, maternal complications and caesarean section rate during labor and APGAR scores in the neonates were recorded. Then data was analysis by Chi-square (χ2) and t-test. The mean time for the 1st stage in the control group was 113.5±47.2 min, compared with 100.64±48.3 min in the hyoscine group that was statistically significant (p = 0.045). There was no significant change in the duration of the 2nd and 3rd stages of labor and no difference in APGAR scores noted at 1 and 5 min, there was a slight (but statistically insignificant) increase in the caesarean section rate. No adverse effect was noted in the group of women receiving hyoscine, compared with the control group. Hyoscine butyl bromide is effective in significantly reducing the duration of the 1st stage of labor and it is not associated with any obvious adverse outcomes in mother or neonate.

Postpartum hemorrhage ranks among the leading causes of maternal morbidity and mortality, both in developed and developing countries. Intravenous Oxytocin is using now to reduce of postpartum hemorrhage. With this trial, researchers sought to determine the effectiveness of oral Misoprostol as an Uterotonic drug in comparison with intravenous Oxytocin in patients with a low risk of postpartum hemorrhage undergoing delivery. To compare the effect of 400 μg of oral Misoprostol with 10 IU of intravenous Oxytocin in preventing postpartum hemorrhage. In a randomized controlled trial conducted in Kosar hospital, 300 pregnant women with inclusion criteria received either 400 μg of oral Misoprostol or 10 IU of intravenous Oxytocin after delivery of the anterior shoulder or within 1 min of delivery. Hemoglobin and hematocrit of maternal was checked during admission and 24 h after delivery and compared together. There was no difference between two groups in hematocrit drop in 3.33±3.44 and 2.81±1.26% of the participants in the Oxytocin and Misoprostol group (p = 0.325). The rate of use of additional oxytocin was higher in the Oxytocin group (34.8 vs. 20.5%, p = 0.013). Shivering was higher in misoprostol group (12.3 vs. 2.9%, p = 0.005). Fever occurred only in 2 cases of Misoprostol group (p = 0.236). The routine use of 400 μg of oral misoprostol was no less effective than 10 IU of intravenous oxytocin in reducing blood loss after delivery as assessed by change in postpartum hematocrit and hemoglobin.