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This subject has a curious history. It never states the obvious. Most likely any encounter with an Alien Civilization would take place through their Robotic Explorers - not unlike our own case. If there were any life form in Mars or Europa - they would had meet our robotic devices.

The "belief' of the importance or relevance of a placebo effect always bothered me in the same way as the power of prayer.

I've never worked on clinical trials statistics so I was never privy to data from double-blind randomized controlled trials (RCT). Someone in the DC's Improbable Science did a great article on the subject.