Anto, Berko Panyin (Kwame Nkrumah University of Science and Technology)

Publication Date

2019-01-01

Funding Reference

The research was financed entirely from researchers' resources. No funding was therefore received from any organization or agency whether public or private

Award Number: Not applicable

Description

Abstract

The antiretroviral therapy outcomes study conducted in Ghana is a multicentre retrospective study among HIV-infected adults offered clinical care at four health facilities in the Ashanti region of Ghana. Demographic and clinical data of patients offered antiretroviral therapy between January 2008 and December 2012 were reviewed. Data were gathered from each patient's hospital records for 36 months beginning from the first day of therapy initiation. The main objective of the study was to investigate treatment outcomes of individual patients after 36 months of therapy. Outcome measures included retention in care, loss to follow-up, mortality, treatment failure and immunologic response to antiretoviral therapy. For patients who were lost to follow up within the study period the duration on treatment before being lost to follow up was also investigated. Data extraction process was started January 2015 and completed in October 2015. Data cleaning and validation was done in July 2016

HIV-infected adults 18 years and above initiated on antiretroviral therapy within the study period

Sampling

From an estimated population of 10,000 HIV-infected adults receiving care from the four treatment site, sample size was calculated to be 370 folder. This was however increased to 450 but 17 folders were rejected due to insufficient data. A total of 433 folders were finally reviewed. Stratified sampling technique was used to apportion appropriate number
of folders to each of the four facilities depending on data volume. The
specific number of folders apportioned to facility was picked from 2008,
2009, 2010, 2011 and 2012 records