NINDS encourages grant applications for research on the cause(s), diagnosis, pathophysiology, and treatment of chronic fatigue
syndrome (CFS). This announcement is made together with 12 other NIH components and is supported by 2 funding mechanisms:
R01 and R21.

CFS is a debilitating and complex syndrome that involves multiple body systems. It is characterized by profound fatigue that
is not improved by bed rest and may be exacerbated or rekindled by physical or mental activity. No specific cause or diagnostic
test has been identified for CFS. Innovative, well-designed studies are needed to provide a better understanding of the disorder,
which will lead to improved diagnostic and intervention strategies.