Description

Biochem/physiol Actions

Preparation Note

200 mg of triamterene is soluble in 4 ml of warm formic acid and yields a clear, yellow-green solution. Triamterene is also soluble in DMSO (5.4 mg/ml), and in 45% (w/v) aqueous 2-hydroxypropyl-β-cyclodextrin (1.2 mg/ml). However, it is insoluble in water.

Application

Triamterene has been used to study its effects on urokinase receptor (uPAR) induction in podocytes under in vitro conditions2. Triamterene has also been identified as an activator compound from a LOPAC library screen using a fluorogenic α-glucosidase assay3.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound was developed by Wellspring. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

The Carcinogen Selector gives researchers the ability to select carcinogens by the mouse organs that they promote cancer in. The tool includes over 750 carcinogens that target 35 specific organs acro...Keywords: Cancer, Carcinogens, Respiratory

The Carcinogen Selector gives researchers the ability to select carcinogens by the mouse organs that they promote cancer in. The tool includes over 750 carcinogens that target 35 specific organs acro...Keywords: Cancer, Carcinogens, Respiratory

Peer-Reviewed Papers

15

References

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