Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Cyclophilin B (CYPB)
No significant cross-reactivity or interference between Cyclophilin B (CYPB) and analogs was observed.

Description:

LS-F4871 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the detection of Human PPIB / Cyclophilin B in samples of Plasma and Serum. It is based upon a Sandwich assay principle and can be used to detect levels of PPIB / Cyclophilin B as low as 134 picograms per milliliter.

Intended Sample Types:

Plasma, Serum

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Detection Range:

78.13 - 5000 pg/ml

Sensitivity:

134 pg/ml

Assay Time:

4.5 h

Precision:

Intra-Assay: CV<10% Inter-Assay: CV<12%

Quality Assurance:

Due to their limited shelf life, LSBio ELISA kits are not typically stocked as finished goods. Upon receipt of an order each kit is assembled and tested to ensure that it meets specifications before shipping. Minor changes may occur to the Range, Sensitivity, and Precision. In the event of a significant change the order would be confirmed with the customer before shipping ELISA kit lot numbers reflect the date of final assembly and testing for each specific kit rather than a bulk manufactured lot. All kits are tested to confirm that they fall within their defined Inter- and Intra- assay coefficient of variation.

Description: PPIB / Cyclophilin B is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.