Targeted acupuncture may offer women with major depression a safe and effective alternative to antidepressant medication, new research suggests.

Investigators at Stanford University School of Medicine in California found that women with major depressive disorder treated with depression-specific acupuncture had a 63% response rate after 12 sessions compared with a 44.3% response rate in 2 combined control groups who were treated with either acupuncture not known to help alleviate depressive symptoms or Swedish massage.

"Pregnancy just by its nature can bring out some underlying psychiatric and emotional issues ... but treatment of depression during pregnancy is critically important so that a woman can maintain her sense of well being and take good care of herself, her fetus and, someday, her child," study coauthor Deirdre Lyell, MD, Stanford University School of Medicine, said in a statement.

Led by Rachel Manber, PhD, the study was published in the March issue of Obstetrics & Gynecology.

Response Rates Significantly Higher

For the study, investigators randomized 150 women whose pregnancies were between 12 and 30 weeks of gestation and who met Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) criteria for major depressive disorder and who scored at least 14 on the 17-item Hamilton Rating Scale for Depression.

Of the 141 women who eventually entered the study, 52 received depression-specific acupuncture, 49 received control acupuncture, and 49 others received Swedish massage.

Treatments were provided twice a week for the first 4 weeks and then weekly thereafter for 4 additional weeks, with each session lasting about 25 minutes.

The investigators found that response rates were significantly higher in women who received depression-specific acupuncture than for either control group. Response rates in women randomized to the 2 control interventions did not differ significantly from each other at 37.5% for the control acupuncture group vs 50% for the massage group.

On the other hand, remission rates did not differ significantly between women who received depression-specific acupuncture at 34.8% and the combined control groups at 29.5%. They also did not differ between those assigned to the control acupuncture group at 27.5% or the massage group at 31.2%.

Thirty-three of the study participants discontinued treatment before the study endpoint, 30% of them for reasons related to the pregnancy. Some women in both acupuncture groups reported transient discomfort at the point of needle insertion, and 1 woman experienced bleeding at the needle site.

Significantly fewer women who received massage reported any adverse effects compared with the 2 acupuncture groups.

Clinically Meaningful

The study authors point out that the benefits observed with depression-specific acupuncture can be considered "clinically meaningful" when assessed in a broader context of depression studies.

Although there are no randomized controlled trials of antidepressants being used during pregnancy, 1 randomized controlled trial found that interpersonal psychotherapy produced a 52% reduction in Hamilton Rating Scale for Depression scores and a 19% remission rate after 16 weeks of therapy, to which the currently study compares very favorably.

According to the study, antidepressant use during pregnancy doubled between 1999 and 2003, but many women are reluctant to take these medications because of safety concerns. In fact, in this particular study, 94% of the women involved expressed reluctance to take an antidepressant because of their pregnancy.

"Because theres this concern about medication among pregnant women and their physicians, its important to find an alternative," said Dr. Manber.

Results from this study therefore suggest that this standardized acupuncture protocol could be considered a "viable treatment option" for depression during pregnancy, the investigators conclude.

Michael Thase, MD, University of Pennsylvania School of Medicine, cautions that findings from this study are preliminary, although they suggest that depression-specific acupuncture may have value in major depressive disorder in this patient population.

On the other hand, another study assessing depression-specific acupuncture in a broader population of men and women with major depressive disorder failed to find a significant effect from the modality, so evidence supporting acupuncture for the treatment of major depressive disorder is not consistent.

"Still there is reason to be cautious when prescribing antidepressants in pregnancy, and one has to weigh the pros and cons of using an antidepressant on an individual basis, he told Medscape Psychiatry.

"If these promising findings are confirmed, it would be good to have another option to complement the focused forms of psychotherapy which are currently used for antenatal depression," he added.

The study was funded by the Agency for Healthcare Research and Quality. The study authors and Dr. Thase have disclosed no relevant financial relationships.

In the 1992 presidential
campaign, Bill Clinton was a heavy underdog to popular incumbent George H. W.
Bush. Bush was considered unbeatable due to foreign policy successes including
the end of the Cold War and routing Saddam Hussein in the first Gulf War. But
Bushs approval ratings, which had been in the 90 percent range, began to dip as
his campaign ignored the economic recession. Clintons campaign manager James
Carvilles now famous campaign slogan, "Its the economy stupid," helped turn
the tide and Bill Clinton became the forty-second American president.

Just like George Bushs 1992
presidential campaign, todays medical community continues to promote the
medical myths associated with cholesterol while ignoring the real cause of
cardiovascular disease, inflammation.

Conventional opinion and
current medical dogma holds that low cholesterol, especially low LDL
cholesterol, reduces the risk and incidence of heart disease and stroke. This
belief is so entrenched in the medical community that the FDA now approves drugs
to prevent heart disease, as it did with Zetia and Vytorin, solely on the
evidence that they lower LDL cholesterol levels. Zetia has never been proven to
reduce heart attacks, strokes or death. Statin drugs help reduce the risk of
heart attack and stroke for those whove already had a cardiac event (one
percent over placebo) but fail to reduce death in women, the elderly, men over
the age of 47, and in men without cardiovascular risk factors.

A 2006 study in The
Archives of Internal Medicine looked at seven trials of statin use in
nearly 43,000 patients, mostly middle-aged men without heart disease. In that
review, statins didnt lower mortality.

Nor did they in a study known
as Prosper, published in The Lancet in 2002, which studied statin use
in people seventy and older. Nor did they in a 2004 review in The Journal of
the American Medical Association, which looked at thirteen studies of
nearly 20,000 women, both healthy and with established heart disease.

Despite a growing voice of
reason, which became even louder after the recently released Enhance study, the
cholesterol zealots continue to view cardiovascular disease with tunnel vision.
This myopic vision fuels the cholesterol drug war which rages on as each
pharmaceutical company seeks to gain economic gain in the 40 billion dollar a
year lipid lowering drug market.

In an attempt to take on the
cholesterol Goliath, Pfizers Lipitor (10 billion dollars in sales annually),
Merck and Schering-Plough combined their cholesterol lowering drugs, Zocor and
Zetia, to form the "super drug" known as Vytorin. Vytorins goal was to lower
LDL cholesterol more than either drug could alone. Zetia lowers blood
cholesterol by blocking the absorption of dietary cholesterol from the
intestines. Zetia used alone is modestly effective in lowering LDL cholesterol
by approximately 17 percent. Zocor alone lowers LDL levels by 36 percentsimilar
to Lipitor.

The hope was that by lowering
LDL to dramatically low levels, Vytorin would do a better job of slowing the
accumulation of fatty plaques in the arteries. Vytorin did, in fact, reduce
LDLby a whopping 51 percent (similar to AstraZenecas Crestor).

However, the two-year
"Enhance" trial failed to prove that Vytorin is better than Zocor alone for
slowing plaque accumulation; instead atherosclerosis worsened in those taking
Vytorin.

Merck and Schering-Plough
suppressed this finding for twenty months.

The study results were not
revealed until the two drug companies were pressured into doing so by an article
in The New York Times and a Congressional inquiry. The marketers of
Vytorin said they had nothing to hide. Its hard to believe they werent just a
little reluctant to publish their highly anticipated study. The news that
Vytorin, which retails for $100 a month and did $2 billion in sales in 2007, was
clinically inferior (perhaps even dangerous) to generic simvastatin (statin),
costing less than $20 a month, obviously wasnt what stockholders wanted to
hear.

Merck and Schering-Plough are
running full-page ads daily in the Times and Wall Street
Journal, warning people not to be confused by a single study and to
continue taking Vytorin. The advice was backed by the American Heart
Association, which the Times reported receives nearly $2 million a year
from Merck/Schering-Plough Pharmaceuticals.

Other LDL lowering drugs have
bitten the dust in the last coupe of years as well.

Pfizers trial of its
much-anticipated drug torcetrapib, which raised HDL, the good cholesterol, and
lowered LDL, had to be stopped in 2006 because the drug caused heart attacks and
strokes.

Estrogen replacement therapy,
which is known to lower LDL cholesterol levels, failed to reduce the incidence
of heart attack and stroke in clinical studies.

Ok, if cholesterol lowering
isnt the answer for everyone, why do statins help people with existing heart
disease? Dr. James K. Liao of Brigham & Womens Hospital in Cambridge,
Massachusetts, has been investigating this question for over a decade. He
suspects that statins have other biological effects. His research shows that
statin drugs not only block cholesterol, but also an inflammation-generating
enzyme known as rho-kinase.

When Liao reduced the
rho-kinase levels in rats, they didnt get heart disease. "Cholesterol lowering
is not the reason for the benefit of statins," he concludes. Of course, there
are dozens of inflammatory chemicals that play a role in triggering
cardiovascular disease. Diet, health habits, our environment, even our
personality may initiate inflammatory chemicals that perpetuate cardiovascular
disease events.

Ralph Waldo Emerson once said,
"People see only what they are prepared to see." As the evidence about
inflammation and cardiovascular disease rises, will conventional medicine and
the public at large be prepared to see that its not about lowering cholesterol
but in reducing inflammation? Hopefully, "Its the inflammation, stupid," will
become a common slogan in the campaign to fight cardiovascular disease.

Rodger Murphree, D.C., has
been in private practice since 1990. He is the founder of, and past clinic
director for a large integrated medical practice, which was located on the
campus of Brookwood Hospital in Birmingham, Alabama. He is the author of
Treating and Beating Fibromyalgia
and Chronic Fatigue Syndrome, Heart Disease What Your Doctor Wont Tell You,
and Treating and Beating Anxiety and Depression with Orthomolecular
Medicine. He can be reached at www.treatingandbeating.com, by email at
drrodgerm@yahoo.com or 1-205-879-2383.

LIVE LOVE LAUGHEvery day can be filled with meaning. Take a moment, just the amount of time you need to take a deep breath and exhale slowly, to ask yourself what is my dream, and how will I get there from here?What can you stop doing or do differently to simplify your life and make it more meaningful? What is truly important to you? Do you give some time each week to your true priorities?Why not fill your life with love and laughter whenever you can? There is no greater gift than the gift of loving others. There is nothing wrong with taking some time for self-care too. Love your pet? Love walking out in nature? Make time for your passions and those things that add value to your life. Your body, mind and soul will thank you.Do you have a mission in life?Dream it. Think about it. Talk about it. Commit to it.

British scientists have found those working more than 11 hours per day increase their risk of heart disease by 67 percent. Considering heart disease is one of the leading causes of death, a two-thirds increase is very significant. This should be a wake-up call for all those workaholics thinking hard work can't kill you. With that said, scientists were not positive of whether it was the long work hours specifically or the things that working long hours could be associated with (poor diets, lack of exercise, increased depression, etc.) that negatively affected heart health. At this point, for those who are stuck working longer hours, it is recommended to minimize other potential risk factors by getting adequate exercise, adhering to a healthy diet, ensuring they receive adequate rest and sleep as well as effectively dealing with any bouts of depression.

A new study finds an astounding one in three hospital stays within the U.S. will be associated with a medical error or mistake. These new findings indicate medical errors are significantly more common than previously thought. In this study, researchers utilized a new tool to help identify medical errors in a review of 795 patient records. In doing so, they were able to identify 10 times the number of medical errors as compared with those found by using the Agency for Healthcare Research's (AHR) process for identifying medical errors. Previous reports of medical errors, many of which were based on the AHR's methods, are likely to have reported far fewer errors than what likely actually occurred. Of the 795 records reviewed in this study, the new method found 354 errors while the AHR's method resulted in the finding of just 35 medical errors. A separate study of medical errors based on insurance claims estimated the annual cost of medical errors resulting in patient harm to be in excess of 17 billion dollars. They found the three most common medical errors were bed sores, post-operative infections and persistent back pain following back surgery.

According to a newly published 10-year study on 38,022 women, omega-3 fatty acid consumption (found at high levels in fish) may help to lessen age-related macular degeneration (AMD). AMD affects millions of older adults in the U.S. alone and is the leading cause of blindness in the elderly. Doctors have been able to prevent the progression of AMD once identified but are still not able to reverse the disease. This study was therefore important to identify what factors if any might be able to prevent AMD for occurring. Researchers found women who consumed foods with higher levels of DHA and EPA, both omega 3-fatty acids, experienced a 38 percent lower risk for AMD and a 34 percent lower risk for AMD, respectively. However, researchers were not positive if the omega-3 fatty acids were responsible for the lower incident of AMD or that those who consumed more omega-3s were also leading healthier lifestyles that were responsible for the lower incidence of AMD. Clearly more research is necessary. Previously, the only known way to help prevent AMD was to never smoke or for smokers, to stop smoking.

ACA Continues to Fight Boy Scouts' Discriminatory Policy, but Public Support is Crucial

The American Chiropractic Association (ACA) today announced that it has developed a template letter for members of the public who oppose the Boy Scouts of America's (BSA) policy change affecting the types of providers allowed to perform annual medical examinations for its youth and adult members. For over a year, the Boy Scouts of America (BSA) has not allowed chiropractic physicians to perform annual evaluations. Medical doctors, doctors of osteopathic medicine, nurse practitioners and physician's assistants are all eligible to perform these exams. The template letter is available online. ACA has sent two letters to BSA headquarters supporting the fact that DCs are qualified to perform annual physicals, voicing its concerns about the policy change and requesting that the previous policy be restored to recognize the state-authorized ability of doctors of chiropractic (DC) to provide annual exams to BSA. The group's decision was not supported by any evidence; in fact, chiropractic physicians performed these evaluations for BSA for more than 22 years prior to the change last year. Furthermore, many DCs are involved with BSA as volunteers, leaders or parents. While ACA is doing its part to rescind this policy, support from the public is crucial. The new template letter is designed to be completed by individuals within the scouting community, such as parents of scouts, troop leaders, troop committee members or council leaders. ACA encourages members of the chiropractic community to inform others about the online template. DCs and others within the chiropractic community are encouraged to contact BSA to voice their concern as well. A template letter for DCs, as well as BSA's phone number and talking points, are available online. The online template letter, when completed, is automatically sent to BSA. The letter for DCs has already generated considerable action by doctors throughout the country. However, despite this action, BSA has refused to rescind or even discuss this policy. The National Board of Chiropractic Examiners (NBCE) and National University of Health Sciences (NUHS) have also sent letters in opposition to this policy, clearly identifying the qualifications of chiropractic physicians to perform annual physical examinations. NUHS has even extended an invitation to BSA to take part in classes on its campus to learn more about chiropractic education. "Chiropractic physicians across the country have enjoyed a long-standing involvement with scouting," said ACA President Rick McMichael, DC. "Chiropractic physicians are primary care doctors who are educated and trained to diagnose health problems, treat conditions that are within their scope of practice and refer patients to other health care practitioners when appropriate. The Boy Scouts of America does everyone a disservice with this discriminatory policy. This policy must be changed."

The American Chiropractic Association (ACA), based in Arlington, Va., is the largest professional association in the United States representing doctors of chiropractic. ACA promotes the highest standards of patient care and ethics, and supports research that contributes to the health and well-being of millions of chiropractic patients. Visit www.acatoday.org.