The proper filter for a therapy question is to search for the desired
level of evidence. For a therapy question, the highest level of
evidence would be a meta-analysis, followed by a systematic review, and
then a single prospective randomized blinded placebo-controlled clinical
trial.

For example, if you wanted to search for information on whether it would
be appropriate to use the antibiotic amoxicillin for a six-month old with
otitis media, you would take the following steps.

1) Click on the link at the bottom of the screen
to enter the MeSH database.

2) Enter the term "otitis media" in the search box. Click in the box next to the term "Otitis Media." Click on the button labeled "Add to Search Builder" on the right side of the screen.

3) Enter the term "amoxicillin" in the search box. Click in the
box next to the term "Amoxicillin". Click on the button labeled "Add to Search Builder" on the right side of the screen.

4) Enter the term "randomized clinical trial" in the search box. Click in the boxes next to "Randomized Controlled Trial as Topic" and "Randomized Controlled Trial [Publication Type]". Click on the button labeled "Add to Search Builder" on the right side of the screen.