The Upper Room reveals the secret trials and tribulations in your average 1940s marriage. The show begins with the question "So, you want to stay married?" The Upper Room covers such serious marital difficulties such as money problems, losing a child, failed businesses, depression, anger, and problems with the in-laws.

Written and produced by Carlton E. Morse, The Upper Room sincerely tries to inspire listeners to work harder at their marriages, to be more forgiving and loving with their families, and to stay devoted to their partnership. Somewhat moralistic, the titles of episodes include "Romantic Life Versus Marital Love", "A Child Shall Lead Them", and "Those Whom God Has Joined Together."