Medicine Overview of Keftil CV 500mg/125mg Tablet

Uses of Cefuroxime

Cefuroxime is used in the treatment of Bacterial infectionsIt is used in serious bacterial infections of various body parts like urinary tract, skin and soft-tissue, blood, brain and lungs (pneumonia). It is also used to prevent infections after surgery.

Side effects of Cefuroxime

Common

Nausea, Diarrhoea, Allergic reaction.

How to use Cefuroxime

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It is better to take Keftil CV 500mg/125mg Tablet with food.Avoid Keftil CV 500mg/125mg Tablet with dietary sodium.

How Keftil CV 500mg/125mg Tablet works

Cefuroxime is a cephalosporin antibiotic. It prevents bacteria from making their own protective cell wall. This causes the bacteria to rupture and finally death.

Uses of Clavulanic Acid

Side effects of Clavulanic Acid

Common

Diarrhoea, Indigestion, Rash, Itching, Vomiting.

How to use Clavulanic Acid

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It is better to take Keftil CV 500mg/125mg Tablet with food.Avoid Keftil CV 500mg/125mg Tablet with dietary sodium.

How Keftil CV 500mg/125mg Tablet works

Clavulanic acid blocks the action of the enzymes produced by bacteria to inactivate the antibiotics.

In Depth Information on Keftil CV 500mg/125mg Tablet

Expert advice for Cefuroxime

Always take the complete course of treatment, as advised by your doctor even if you feel better.

Never take an antibiotic for a viral infection like a cold or the flu.

Can lead to nausea and diarrhoea frequently. If this becomes severe or persistent or you notice that your stool contains blood or mucus you should stop taking Cefuroxime immediately and consult your doctor.

Inform your doctor if you develop a rash or other unexpected symptoms.

Inform your doctor if there is the previous history of drug allergy.

Inform your doctor if you have ever been diagnosed with kidney or liver problems.

Expert advice for Clavulanic Acid

Take clavulanic acid containing antibiotics along with food and with plenty of fluids.

Do not start or continue the clavulanic acid containing antibiotic tablets and consult your doctor, if you are allergic (hypersensitive) to clavulanic acid, penicillins or any of the other ingredients of this drug.

Do not take the drug without consulting your doctor, if you have kidney or liver problems.

Do not take the drug without consulting your doctor, if you have any serious allergic reaction (skin rash, inflammation of blood vessels, fever, joint pain, swollen glands in neck, armpit or groin, swelling of face or mouth [angioedema], difficulty breathing, or collapse).

Do not take clavulanic acid, if you have had penicillin-associated jaundice or skin rash, kidney or liver dysfunction.

Warnings

Special precautions for Keftil CV 500mg/125mg Tablet

Alcohol

Interaction with alcohol is unknown. Please consult your doctor.

Pregnancy

PROBABLY SAFE

Keftil CV 500mg/125mg Tablet is probably safe to use during pregnancy.

Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.

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Lactation

CAUTION

Keftil CV 500mg/125mg Tablet should be used with caution dur

ing lactation.
Breast feeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

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Driving

Not relevant, as Keftil CV 500mg/125mg Tablet is intended for use in hospitalised patients.

Kidney

UNSAFE

Keftil CV 500mg/125mg Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.

Caution to be advised in patients with impaired renal function.

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Liver

There is no data available. Please consult doctor before consuming the drug.

Frequently asked questions for Keftil CV 500mg/125mg Tablet

Frequently asked questions for Cefuroxime

Yes, Cefuroxime is an antibiotic. It is a second-generation cephalosporin antibiotic used to treat various infections.

Q. Is Cefuroxime a form of penicillin drug?

Cefuroxime belongs to the cephalosporin antibiotics and is not a penicillin drug. However, its chemical structure and action is similar to penicillin.

Q. Is Cefuroxime safe?

Cefuroxime is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q. Is Cefuroxime a steroid?

Cefuroxime is not a steroid molecule. It is an antibiotic which belongs to the group of cephalosporins.

Q. Is Cefuroxime safe in G6PD deficiency?

Cefuroxime is not known to cause hemolysis in glucose-6-phosphate dehydrogenase (G6PD) deficient individuals. However, ask your doctor before taking Cefuroxime if you are G6PD deficient.

Q. Is Cefuroxime a fluoroquinolone?

Cefuroxime is not a fluoroquinolone. It is a second-generation cephalosporin antibiotic which is different from fluoroquinolones.

Q. Is Cefuroxime useful in the treatment of urinary tract infection (UTI)?

Cefuroxime is indicated for the treatment of uncomplicated urinary tract infection (UTI). Its effectiveness would depend on the infecting organism and hence you should consult your doctor for the right diagnosis and treatment.

Q. Can Cefuroxime be taken with azithromycin?

Cefuroxime is not known to have any clinically meaningful interaction with azithromycin. However, both are antibiotics and should be used only when advised by the doctor.

Q. Can Cefuroxime be taken with doxycycline?

Cefuroxime is not known to have any clinically meaningful interaction with doxycyclin. However, both are antibiotics and should be used only when advised by the doctor.

Q. Is it safe to take Cefuroxime with pseudoephedrine?

Cefuroxime is not known to have any clinically meaningful interaction with pseudoephedrine. However, interactions can occur. Ask your doctor before taking the drugs together.

Q. Can Cefuroxime be taken with naproxen?

Cefuroxime is not known to have any clinically meaningful interaction with naproxen. However, interactions can occur. Ask your doctor before taking the drugs together.

Q. Is it safe to take Cefuroxime with paracetamol (acetaminophen)?

Cefuroxime is not known to have any clinically meaningful interaction with paracetamol. However, interactions can occur. Ask your doctor before taking the drugs together.

Q. Does Cefuroxime have sulfa in it?

Cefuroxime has a sulfur molecule in its structure. However, it is a beta-lactam antibiotic and allergic reactions due to the drug are because of the beta-lactam ring present in its structure. Report to your doctor if you are allergic to penicillins, cephalosporins, or sulfa drugs before taking the drug.

Q. Does Cefuroxime expire?

Cefuroxime like any other drug has an expiry data and should not be used after that. Please check the package insert before using the medicine.

Q. Can Cefuroxime help to treat pneumonia?

Cefuroxime is indicated in the treatment of pneumonia. However, its effectiveness would depend on the infecting organism and hence you should consult your doctor for the right diagnosis and treatment.

Q. Does Cefuroxime have penicillin in it?

No, Cefuroxime does not have penicillin in it. It is a cephalosporin antibiotic which is similar to penicillin.

Q. Can the use of Cefuroxime cause constipation?

Cefuroxime is not known to cause constipation. It is associated with diarrhea. However, if you experience any such symptom while taking Cefuroxime, consult your doctor.

Q. Does Cefuroxime cover staphylococci?

Yes, Cefuroxime is active against staphylococcus. However, strains resistant to the drug have also been reported. Talk to your doctor for the right diagnosis and treatment of your infection.

Q. Can the use of Cefuroxime make you feel tired?

Cefuroxime use is not associated with tiredness. However, if you experience tiredness while taking Cefuroxime, consult your doctor.

Q. Can I take alprazolam with Cefuroxime?

No drug interactions have been reported when Cefuroxime is used with alprazolam. However, interactions can occur. Please consult your doctor before taking the two medicines together.

Q. Can I take Cefuroxime with ibuprofen?

No drug interactions have been reported when Cefuroxime is used with ibuprofen. However, interactions can occur. Please consult your doctor before taking the two medicines together.

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Frequently asked questions for Clavulanic Acid

Q. What is Clavulanic Acid?

Clavulanic Acid is a beta-lactamase inhibitor. It does not exert a clinically useful antibacterial effect on its own. It is used in combination with other antibiotics to increase their effect.

Q. What does clavulanic acid do when added to amoxicillin?

Amoxicillin is a semisynthetic penicillin (beta-lactam antibiotic) that is easily broken down by beta-lactamase enzyme produced by some bacteria. Clavulanic acid inactivates the beta-lactamase enzymes thereby preventing the breakdown of amoxicillin.

Amoxicillin/clavulanic acid combination is not effective against methicillin-resistant Staphylococcus aureus (MRSA) infections. Consult a doctor for the right choice of antibiotic for your infections.

Q. What are the side effects of amoxicillin/clavulanic acid combination?

Common side effects associated with the use of Amoxicillin/clavulanic acid combination are diarrhea, nausea, vomiting, and mucocutaneous candidosis. Talk to your doctor in case you experience these or other side effects while taking amoxicillin clavulanic acid combination.

Q. Is amoxicillin/clavulanic acid combination is safe in patients with a G6PD deficiency?

There is no study or research available regarding the safety of amoxicillin/clavulanic acid in G6PD deficiency. Talk to your doctor regarding its use in G6PD deficient patients.

Q. Is amoxicillin/clavulanic acid combination nephrotoxic?

Amoxicillin/clavulanic acid combination can cause kidney damage, especially if taken a dose more than recommended. Inflammation of the kidney tissue (interstitial nephritis), hematuria (blood in urine) and crystalluria (crystals in urine) has been reported in some patients. Always take a dose as recommended by your doctor and share your medical history of kidney disease if any when you are prescribed this combination.

Q. Does amoxicillin/clavulanic acid contain sulfa?

No, amoxicillin/clavulanic acid does not contain any sulfa substance.

Q. Do amoxicillin/clavulanic acid combination make you drowsy or tired?

Amoxicillin/clavulanic acid combination does not make you feel drowsy or tired. However, it can make you feel dizzy. Talk to your doctor if you have these symptoms while taking this combination.

Q. Is amoxicillin/clavulanic acid combination is effective against pseudomonas infections?

Amoxicillin/clavulanic acid combination is not effective against pseudomonas infections. Consult a doctor for the right choice of antibiotic for your infections.

Q. Where to buy Clavulanic Acid?

Clavulanic Acid does not have any antibacterial activity of its own and is not available as a single salt in the market. It is always available as a combination with antibiotics like amoxicillin, cefixime, and cefuroxime. Talk to your doctor before taking any antibiotics.

Q. Why does Clavulanic Acid cause diarrhea?

Clavulanic Acid iself is not known to cause diarrhea. However, it is always given in combination with a beta-lactam antibiotic and diarrhea is a common side effect associated with the use of this combination.

Q. What are the side effects of Clavulanic Acid?

Clavulanic Acid can cause hepatitis and allergy. However, since the drug is always given in combination with a beta-lactam antibiotic, there can be many side effects of this combination. Consult your doctor if you experience any side effects while using this combination.

Q. What is the dose of Clavulanic Acid?

The dose of Clavulanic Acid depends on the age of the patient and disease for which it is given. Consult your doctor for the appropriate dose, frequency, and duration of the drug.

Q. What is the mechanism of action of Clavulanic Acid?

Clavulanic Acid is a beta-lactamase inhibitor. It inactivates beta-lactamase enzyme produced by some bacteria and prevents the inactivation of the antibiotic when given along with it.

Q. What is the molecular weight of Clavulanic Acid?

The molecular weight of Clavulanic Acid is 199.16 g/mol.

Q. Can Clavulanic Acid cause allergy?

Clavulanic Acid may cause allergy but the chances of it causing an allergy is far less likely compared to the penicillins it is given along with. Consult your doctor if you have any allergic reactions while taking the drug.

Q. Can I take clavulanic acid with alcohol?

Clavulanic acid can be taken with alcohol. No interactions have been reported between the two. However, interactions can occur. Talk to your doctor regarding its use with alcohol.

Q. Can clavulanic acid be taken with cefuroxime?

Fixed dose combinations of cefuroxime with clavulanic acid are available in India. However, there is not enough research to prove the efficacy and safety of cefuroxime combined with clavulanic acid.

Q. Can I take clavulanic acid with penicillin?

Clavulanic acid is a beta-lactamase enzyme inhibitor which is available as a fixed-dose combination penicillin antibiotics like amoxicillin and ticarcillin. It is not available for use as a single agent. Talk to your doctor for further information on the same.

Q. Is clavulanic acid available in combination with cefixime?

Fixed dose combinations of cefixime with clavulanic acid are available in India. However, there is not enough research to prove the efficacy and safety of cefixime combined with clavulanic acid.

Q. Can I take Clavulanic Acid with food?

Food generally does not affect the absorption of Clavulanic Acid. The drug can be taken with or without food. However, there is evidence that a high-fat diet may interfere with the absorption of Clavulanic Acid.

Q. Can I take amoxicillin/clavulanic acid combination with paracetamol?

Amoxicillin/clavulanic acid combination can be taken with paracetamol (acetaminophen). No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.

Q. Is clavulanic acid and sulbactam same?

Sulbactam is a beta-lactamase inhibitor like clavulanic acid. They do not have any action on the bacteria. Clavulanic acid is commonly combined with amoxicillin and sulbactam is commonly combined with ampicillin. They increase the antibacterial action of these antibiotics.

Q. Is clavulanic acid same as dicloxacillin?

Dicloxacillin is a beta-lactam antibiotic whereas clavulanic acid is a beta-lactamase inhibitor. Dicloxacillin is not combined with clavulanic acid since it is inherently resistant to degradation by beta-lactamase enzyme and would not need any inhibitor for increasing its action.

Q. Can I take amoxicillin/clavulanic acid combination with azithromycin?

The effect of amoxicillin/clavulanic acid combination can be decreased when given with azithromycin. Talk to your doctor before taking the two antibiotics together.

Q. Can I take amoxicillin/clavulanic acid combination with alprazolam?

Amoxicillin/clavulanic acid can be taken with alprazolam. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.

Q. Can I take amoxicillin/clavulanic acid combination with guaifenesin?

Amoxicillin/clavulanic acid can be taken with guaifenesin. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.

Q. Can I take amoxicillin/clavulanic acid combination with lisdexamfetamine?

Amoxicillin/clavulanic acid can be taken with lisdexamfetamine. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.