Prospective Randomized Comparison of Transurethral Resection by Mean of White Light and Narrow Band Imaging

Summary

To date, fluorescence and narrow band imaging cystoscopy have been tested in many
prospective within patient trials but only as an "add on" procedure. This results in a bias
that does not allow to determine the real impact of such innovative technologies on bladder
cancer management. Hereby we propose the first prospective randomized trial which compares
narrow band imaging trans urethral resection as a stand alone procedure versus white light
transurethral resection. The primary end point is to assess the recurrence rate of bladder
cancer lesions with each treatment modality. The study is designed to disclose an inferior
recurrence rate (estimated 10%) in the group treated by narrow band imaging transurethral
resection respect to the control group, treated by standard transurethral resection.

Transurethral resection of bladder cancer (TURB) is the critical step in the management of nonmuscle invasive bladder cancer (NMIBC). This review presents new improvements in the strategy and techniqu...

Urethral stricture is a well-known complication after transurethral surgeries. The incidence of urethral stricture after transurethral resection of prostate (TURP) varies between 2.2 and 9.8%. Most of...

The standard of care in non-muscle invasive bladder cancer consists of transurethral tumor resection. The aim of this study was to evaluate the influence of transurethral resection of bladder tumor (T...

To characterize the perioperative morbidity of transurethral resection of bladder tumor (TURBT) in order to identify important determinants of both quality and cost in the delivery bladder cancer care...

Transurethral resection of bladder tumor (TURBT) aims at complete resection of all the visible tumors. Existing guidelines recommend restage TURBT in all patients with T1 and high-grade tumors, to avo...

Medical and Biotech [MESH] Definitions

Prostatectomy

Complete or partial surgical removal of the prostate. Three primary approaches are commonly employed: suprapubic - removal through an incision above the pubis and through the urinary bladder; retropubic - as for suprapubic but without entering the urinary bladder; and transurethral (TRANSURETHRAL RESECTION OF PROSTATE).

Transurethral Resection Of Prostate

Removal of all or part of the PROSTATE, often using a cystoscope and/or resectoscope passed through the URETHRA.

Gardnerella Vaginalis

The only species in the genus GARDNERELLA, and previously classed as Haemophilus vaginalis. This bacterium, also isolated from the female genital tract of healthy women, is implicated in the cause of bacterial vaginosis (VAGINOSIS, BACTERIAL). It occasionally causes postpartum bacteremia and bacteremia following a transurethral resection of the prostate.

Narrow Band Imaging

Imaging techniques that use illumination created with several optical interference filters by which the frequency ranges are spectrally narrowed and light scatter is greatly reduced. Thus the reflected photons reconstituting the images are from distinct depths (the surface and deeper layers) of the object being imaged.

Vulvectomy

Surgical resection of the VULVA.

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Relevant Topics

Prostate CancerProstate cancer (cancer de prostata)
Prostate cancer (cancer de prostata) is a form of cancer that develops in the prostate, a gland in the male reproductive system. Most prostate cancers are slow growing; however, there are cases of aggressive prostat...