Sgt. Fury and his Howling Commandos were created by Stan Lee and Jack Kirby. Sgt. Fury and his Howling Commandos followed an elite special unit, the First Attack Squad, nicknamed the "Howling Commandos," which was stationed in a military base in England to fight missions primarily, but not exclusively, in the European Theatre of World War II. Under Captain "Happy Sam" Sawyer, Fury was the cigar-chomping noncom who led the racially and ethnically integrated unit, unusual for the time. The main character, Sgt. Nick Fury, later became the leader of Marvel's super-spy agency, S.H.I.E.L.D..

All issues beginning with #120 are reprints of early issues. Some issues were also reprinted in "Special Marvel Edition".