Innate Immunity to Influenza Virus Infection
The authors discuss the various ways in which the innate immune system uses pattern recognition receptors to detect and respond to influenza virus infection. They consider whether the outcome of innate sensor stimulation promotes antiviral resistance or disease tolerance, and propose rational treatment strategies for the acute respiratory disease that is caused by influenza virus infection. [Nat Rev Immunol]Abstract

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SCIENCE NEWS

Coral Reefs Provide Potent New Anti-HIV Proteins
Researchers have discovered a new class of proteins capable of blocking the HIV virus from penetrating T-cells, raising hope that the proteins could be adapted for use in gels or sexual lubricants to provide a potent barrier against HIV infection. The proteins, called cnidarins, were found in a feathery coral collected in waters off Australia’s northern coast. [Press release from ScienceDaily discussing research presented at Experimental Biology 2014, San Diego]Abstract