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Mangiferin (a pharmacologically active hydroxylated xanthone C-glycoside) is extracted from mango at high concentrations from the young leaves (172 g/kg), bark (107 g/kg), and from old leaves (94 g/kg).[8] Allergenic urushiols are present in the fruit peel and can trigger contact dermatitis in sensitised individuals. This reaction is more likely to occur in people who have been exposed to other plants from the family Anacardiaceae, such as poison oak and poison ivy, which are widespread in the United States.[9]

The tree is more known for its fruit rather than for its timber. However, mango trees can be converted to lumber once their fruit bearing lifespan has finished. The wood is susceptible to damage from fungi and insects.[11] The wood is used for musical instruments such as ukuleles,[11] plywood and low-cost furniture.[12] The wood is also known to produce phenolic substances that can cause contact dermatitis.[13]