mirrorball® Imaging Cytometer for Antibody Discovery

mirrorball ® – antibody screening on a plate The mirrorball high sensitivity cytometer represents one of the most versatile instruments available for antibody screening. The system embodies TTP Labtech’s laser scanning technology and enables streamlined workflows for unprecedented levels of throughput. mirrorball offers the benefits of a no-wash mix-and-read assay protocol. The throughput con...read more

Description

mirrorball® – antibody screening on a plate

The mirrorball high sensitivity cytometer represents one of the most versatile instruments available for antibody screening. The system embodies TTP Labtech’s laser scanning technology and enables streamlined workflows for unprecedented levels of throughput. mirrorball offers the benefits of a no-wash mix-and-read assay protocol. The throughput contrasts with traditional methods such as ELISA and flow cytometry, which can represent a bottleneck in the antibody discovery process as they require lengthy, multi-step preparation stages, large cell numbers and amounts of costly reagents. By offering analysis of samples in microplates without washing or flow-based detection, mirrorball is able to address soluble and cell-surface antigens expressed on adherent and suspension cell lines and thus presents a complete screening solution.

mirrorball provides many benefits including:

no wash steps required

sample integrity is retained

antibody interactions with low affinity and/or high dissociation rates can be detected

retains antigen conformation – able to scan adherent cells without any manipulation