Test Directory

IHC: Calponin IHC: Calponin

Specimen Requirements

Paraffin block or wet tissue

Method

Immunohistochemistry (IHC)

Schedule

Mon-Fri

Turn-Around Time

24 hrs

Instructions/Notes

Formalin-Fixed, Paraffin-Embedded

Clinical Utility

The expression of calponin is restricted to smooth muscle cells. Expression of the 29kDa form isprimarily restricted to muscle of the urogenital tract. Calponin also labels myoepithelial cells andcan be useful in distinguishing in situ from infiltrating breast carcinoma.