Pharmacopoeias.

Ph. Eur. 6.2

(Thioctic Acid). A yellow, crystalline powder. M.p. about 61°. Very slightly soluble in water; very soluble in dimethylformamide; freely soluble in methyl alcohol. Protect from light.

USP 31

(Alpha Lipoic Acid). M.p. 60.0° to 62.0°.

💊 Profile

Thioctic acid is used for its antoxidant effects in the treatment of diabetic neuropathy. It has been tried in the treatment of liver dysfunction and in subacute necrotising encephalopathy. Beneficial results have been claimed in amanitin poisoning after ingestion of the mushroom Amanita phalloides, but such use is controversial. Ethylenediamine thioctate, sodium thioctate, thioctic acid amide (thioctamide), and trometamol thioctate have been used similarly.

Diabetic neuropathy.

References1-5 to the benefits of thioctic acid in diabetic neuropathy.