The purpose of this study is to evaluate the effects of experimental knee pain on the muscle strength gain after 8 weeks of strengthening exercises for the quadriceps. It is hypothesized that experimental knee pain will reduce the muscle strength gain following strengthening exercises in healthy volunteers.

non-painful injections of isotonic saline into the infrapatellar fatpad.

Other: Non-painful control injections

Injection of isotonic saline into the infrapatellar fat pad

Eligibility

Ages Eligible for Study:

20 Years to 35 Years

Genders Eligible for Study:

Both

Accepts Healthy Volunteers:

Yes

Criteria

Inclusion Criteria:

aged between 20 to 35 years

healthy

untrained (non-regular exercise participation [i.e. < 1 day/week])

Exclusion Criteria:

symptomatic musculoskeletal diseases

history of traumatic injuries to muscles, tendons or joints of the lower extremity

knee joint pain within a month prior to enrollment

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.