A former Real Housewife is going to take a fictional one under her wing.

In an upcoming episode of ABC’s The Neighbors, Bethenny Frankel will guest star as a businesswoman who offers to help launch Debbie Weaver’s (Jami Gertz) handbag business.

The episode, titled “Mo Purses Mo Money Mo Problems,” is shooting this week and expected to air in March or April.

While Frankel, who recently announced her impending divorce from husband Jason Hoppy, has appeared on a series of reality shows – including The Apprentice: Martha Stewart and her Housewives spin-offs Bethenny Getting Married/Bethenny Ever After – this will mark her first time appearing on a network primetime scripted TV series. Her talk show Bethenny will air in syndication fall 2013.