acrodermatitis

1. chronic inflammation of the skin of the extremities, leading to atrophy.

2. a diffuse chronic skin disease usually confined to the limbs, seen mainly in women in Northern, Central, and Eastern Europe, and characterized initially by an erythematous, edematous, pruritic phase followed by sclerosis and atrophy. It is caused by infection with Borrelia burgdorferi. See also lyme disease.

acrodermatitis conti´nua (continuous acrodermatitis) chronic inflammation of the skin of the limbs, in some cases becoming generalized.

enteropathic acrodermatitis (acrodermatitis enteropa´thica) a hereditary disorder of infancy due to defective zinc uptake, characterized by dermatitis with vesicles and pustules, usually around the mouth or anus and on the head, elbows, knees, hands, and feet; there are also gastrointestinal disturbances such as diarrhea, as well as total alopecia.

ac·ro·der·ma·ti·tis en·ter·o·path·'i·ca

[MIM*201100]

a progressive hereditary defect of zinc metabolism in young children (onset, 3 weeks-18 months); often manifests first as a blistering, oozing, and crusting eruption on an extremity or around one of the orifices of the body, followed by loss of hair and by diarrhea or other gastrointestinal disturbances; relieved by lifelong oral zinc supplementation; autosomal recessive trait.

acrodermatitis enteropathica

[en′tərōpath′ikə]

a rare, chronic disease of infants characterized by vesicles and bullae of the skin and mucous membranes, alopecia, diarrhea, and failure to thrive. An autosomal-recessive disorder of zinc malabsorption, the disease may be lethal if not treated. Zinc sulfate is usually prescribed.

ac·ro·der·ma·ti·tis en·ter·o·path·i·ca

(ak'rō-dĕr'mă-tī'tis en'tĕr-ō-path'i-kă)

A progressive hereditary defect of zinc metabolism in young children (onset, 3 weeks-18 months); often manifests first as a blistering, oozing, and crusting eruption on an extremity or around one of the orifices of the body, followed by loss of hair and by diarrhea or other gastrointestinal disturbances; relieved by lifelong oral zinc supplementation; autosomal recessive trait.

acrodermatitis enteropathica

A rare genetic skin inflammation (DERMATITIS), affecting mainly the extremities, with reddening, ulceration and pustule formation. The condition is caused by the inability to absorb zinc from the diet and can be treated by zinc supplements.

ac·ro·der·ma·ti·tis en·ter·o·path·i·ca

(ak'rō-dĕr'mă-tī'tis en'tĕr-ō-path'i-kă) [MIM*201100]

Progressive hereditary defect of zinc metabolism in young children; often manifests first as a blistering, oozing, and crusting eruption on a limb or around an orifice; relieved by lifelong oral zinc supplementation.

One well-known zinc-deficiency disorder with overt clinical signs is acrodermatitis enteropathica, a genetic autosomal recessive disease with an inborn defect in metabolism that results in reduced intestinal absorption of zinc (19).

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