This thesis describes an efficient synthesis of 5,6-substituted enlactones starting from (R,R)-tartaric acid as an easy available chiral source. First a lactone-ring compound was synthesised. Wittig reaction of this lactone-compound in form of its aldehyde with various side chain compounds afforded readily the desired enlactones. By using different side chain compounds the described sequence allows now the synthesis of a wide variety of 5,6-substituted enlactones in only 9 to 10 steps.