Application Information: DDX46 antibody, Internal

Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.

Predicted Target Size

117 KDa (note)

Positive Controls

MCF-7

Form Supplied

Liquid

Concentration

0.5-1
mg/ml

Purification

Affinity Purified

Specifications: DDX46 antibody, Internal

Full Name

DEAD-box helicase 46

Background

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. [provided by RefSeq, Jul 2008]

Synonyms

PRPF5 Antibody , PRP5 Antibody , DDX46 Antibody

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

A synthetic peptide corresponding to an Internal region of Human DDX46