Jacking In to the Matrix Franchise examines the films, video and computer games, comics, anime short films and other aspects of the franchise. The book is organized as a series of essays on the cultural and religious implications of the Matrix franchise, including gender, race, ethics, religion, and cybernetics. Contributors include John Shelton Lawrence, Russell Blackford, Matthew Kapell, Bruce Isaacs, and William G. Doty.

The title phrase "jacking into the matrix" appears frequently in (and is probably a reference to) the novel Neuromancer by William Gibson.