Multicellular co-culture, with meaningful organization into models of biological systems.

Control over chemical gradients and flow across the gel region and/or within the media channels.

Novel posts enable easy gel filling & long working regions

AIM 3D Cell Culture Chips utilize a patented approach with a novel post design in conjunction with optimized post spacing & channel height. This allows hydrogels to be contained within gel channels during the hydrogel filling process, with little risk of leaking into adjacent channels. The DAX-1 chip, for instance, has a 14mm long gel region. The air-liquid interface is substantially flat & uniform, with minimal occurrence of concave (under-filled) or convex (over-filled) interfaces. As the hydrogel is caged within the gel channel, the meniscus that usually obstructs phase contrast imaging is also absent. In short, AIM chips make it easy for users to cast hydrogels for 3D cell culture, and provide excellent optical clarity for various imaging techniques.Gas permeable laminate

AIM 3D Cell Culture Chips are fabricated with gas permeable laminates to ensure that oxygen tension in each chip correctly reflects incubator conditions. Users have the flexibility of setting up normoxic or hypoxic culture conditions.