CTSB Mouse, Active

Catalogue number

PRO-2377

Synonyms

Cathepsin B, Cathepsin B1, CTSB.

Introduction

Cathepsin B preproprotein (CTSB) is a papain-family cysteine protease which is normally located in lysosomes. CTSB is able to degrade several extracellular matrix components at both neutral and acidic pH and has been implicated in the progression of some human and rodent tumors progression and arthritis.

Description

CTSB Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 330 amino acids (18-339a.a.) and having a molecular mass of 36.4kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).

CTSB is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.