Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.167.194.4. If your access is via an institutional subscription, please contact your librarian to request reinstatement. If you are using a personal subscription, please contact the publisher.

The full content of Annals is available to subscribers

Abstract

Every now and then in the literature of medicine, a text appears that seems certain to become a tradition, if not a classic. The Smith/Thier treatise on pathophysiology is, I believe, such a text. It is to be the first volume in a proposed International Textbook of Medicine triology. The second volume is the text on infectious diseases edited by Braude, Davis, and Fierer. The third is the Cecil Textbook of Medicine.

An authoritative, complete, and up-to-date textbook of pathophysiology has long been needed. This discipline, as the authors emphasize, is central to the intelligent study of human disease. The