My previous post highlighted how the imaging community is leveraging NCIP Hub’s capabilities to run its image analysis needs and to collaborate on tool development. This post discusses how the NCI plans to use NCIP Hub to address the need for robust, reliable translational use of mouse and human-in-mouse models. The NCI established the Mouse …

Researchers are using 3D printing to gain insights that contribute to advances in basic biomedical research and the development of precision medical therapies by creating 3D models of pathogens, tumors, normal tissues, cells, and biomolecules. Dr. Sriram Subramaniam, principal investigator in the Laboratory of Cell Biology at the NCI Center for Cancer Research (CCR), uses …

In his earlier post, Ishwar Chandramouliswaran introduced the objectives of the NCIP Hub, an online resource for research and collaboration in cancer informatics. As a scientific repository, the NCIP Hub can store community-generated data, tools, and other resources. Members can upload tools, conduct analyses, and collaborate, giving researchers the opportunity to engage with and leverage …

One of the major goals of the NCIP is to help facilitate open innovation and scientific collaboration in the cancer research and informatics community. To that end, we have undertaken several projects, two of which were the focus of previous NCIP blog posts: The Cancer Genomics Cloud Pilot, an initiative to democratize access to and …

To the Cancer Informatics Community, As you may know, Dr. George Komatsoulis, Deputy Director of the NCI Center for Biomedical Informatics and Information Technology (CBIIT), will be leaving the NCI on May 2, 2014 to join the National Center for Biotechnology Information (NCBI) at the National Library of Medicine, where he will be focusing on …

While working with big genomics data can be very challenging, it can also be fun. And when your team wins a competition, it’s positively exhilarating, as our NCIP Computational Genomics Research Group discovered while participating in the 8th annual set of challenges posed by The Dialogue on Reverse Engineering Assessment and Methods (DREAM) project. DREAM …

On September 4, 2013, NCI’s Clinical Proteomics Tumor Analysis Consortium (CPTAC) publicly released proteomic data produced from colorectal tumor samples previously analyzed as part of The Cancer Genome Atlas (TCGA) initiative. This is the first release of proteomic tumor data designed to complement genomic data from the same tumors. Since its launch in 2006, the …

The Pathway Interaction Database (PID) is a collection of biomolecular interactions and events involving signaling and regulatory pathways that have been curated from the peer-reviewed literature. Users are able to browse through biomolecular interactions, run computational analyses, or synthesize and combine interactions to establish novel pathways. Begun as a collaborative project between the National Cancer …

I was fortunate enough to attend the Bioinformatics Open Source Conference (BOSC) this summer and heard a wonderful talk by Cameron Neylon on “The Role of Open Source and Open Thinking.” In his talk, he presented a clever equation for calculating the probability of helping someone through an open source project: P (of helping someone) …

Through this blog, we are pleased to provide you with regular updates on the NCI Cancer Genomics Cloud Pilots. In a recent post, George Komatsoulis discussed the NCI Board of Scientific Advisors’ unanimous approval of the project concept. He also announced the release of a Sources Sought notice, an opportunity for the technical community to …