RD

Quantitatively determines RNA degradation on the short-read distribution of individual transcripts. RD aims to characterize and adjust the position-dependent bias in RNA-Seq for individual transcripts. This tool can improve the accuracy of transcript isoform expression estimation.

Supported by National Institutes of Health (P50 HG 002790 and 1 U01 HL108634); by National Natural Science Foundation of China (60928007 and 60805010) and Tsinghua National Laboratory for Information Science and Technology (TNLIST) Cross-discipline Foundation.