From all I've read Grape Seed Extract is an acceptable substitute for the more expensive Pycnogenol so I'm alternating these two products in my daily regime. Should save a lot of money as Pycnogenol is more expensive.

Been using it only for a week and already could tell the difference.Better sleeping patterns, I just generally feel good.!! Just bought 2 more to stock up.! Much cheaper than pycnogenol but effectiveness, I believe this is better.