Jenner was partially responding to Cruz's support for a North Carolina law that restricts the use of public bathrooms to individuals of the same biological sex, whichessentially bars transgender individuals from using bathrooms that conform with their expressed gender identity.

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Ted Cruz on North Carolina bathroom law: 'This isn't about the Caitlyn Jenners of the world'

Republican U.S. presidential candidate Ted Cruz stands with Carly Fiorina after he announced Fiorina as his running mate at a campaign rally in Indianapolis, Indiana, United States April 27, 2016. REUTERS/Aaron P. Bernstein - TPX IMAGES OF THE DAY

Republican presidential candidate Sen. Ted Cruz, R-Texas, hugs former Hewlett-Packard CEO Carly Fiorina during a rally in Indianapolis, Wednesday, April 27, 2016, where he announced he has tapped Fiorina as his running mate. (AP Photo/Michael Conroy)

A supporter of Republican U.S. presidential candidate Ted Cruz holds up a new campaign sign reflecting Cruz's choice of Carly Fiorina as his running mate at a campaign rally in Indianapolis, Indiana, United States April 27, 2016. REUTERS/Aaron P. Bernstein

Republican U.S. presidential candidate Ted Cruz is joined by former Republican presidential candidate and recently announced supporter Carly Fiorina at a Cruz town hall event at the Faith Assembly of God in Orlando, Florida U.S. March 11, 2016. U.S. Republican presidential candidate Ted Cruz is expected to announce former business executive Carly Fiorina will be his vice presidential running mate if he wins the party's nomination, ABC News affiliate WMUR reported, citing unnamed sources. REUTERS/Kevin Kolczynski/File Photo TPX IMAGES OF THE DAY

A supporter of Republican U.S. presidential candidate Ted Cruz holds up a new campaign sign reflecting his choice of Carly Fiorina as his running mate at a campaign rally in Indianapolis, Indiana, United States April 27, 2016. REUTERS/Aaron P. Bernstein

Former U.S. Republican presidential candidate Carly Fiorina speaks to the crowd during a Ted Cruz campaign rally at American Legion Post 22 in Towson, Maryland, April 18, 2016. REUTERS/Bryan Woolston

Republican U.S. presidential candidate Senator Ted Cruz, with his daughter Catherine (2nd L), wife Heidi (C), daughter Caroline (2nd R) and supporter and former rival Carly Fiorina (R) at his side, reacts to the primary election results in Florida, Ohio and Illinois during a campaign rally in Houston, Texas March 15, 2016. REUTERS/Trish Badger EDITORIAL USE ONLY. NO ARCHIVES. NO RESALES.

Former U.S. Republican presidential candidate Carly Fiorina watches as U.S. Republican presidential candidate Ted Cruz speaks with the media ahead of a campaign rally in Rothschild, Wisconsin, U.S. March 28, 2016. U.S. Republican presidential candidate Ted Cruz is expected to announce former business executive Carly Fiorina will be his vice presidential running mate if he wins the party's nomination, ABC News affiliate WMUR reported, citing unnamed sources. REUTERS/Mark Kauzlarich/File Photo

Former U.S. Republican presidential candidate Carly Fiorina speaks at a campaign rally in support of U.S. Republican presidential candidate Ted Cruz in Rothschild, Wisconsin, U.S. March 28, 2016. U.S. Republican presidential candidate Ted Cruz is expected to announce former business executive Carly Fiorina will be his vice presidential running mate if he wins the party's nomination, ABC News affiliate WMUR reported, citing unnamed sources. REUTERS/Mark Kauzlarich/File Photo

U.S. Republican presidential candidate Ted Cruz (R) speaks with the media as former U.S. Republican presidential candidate Carly Fiorina stands by his side ahead of a campaign rally in Rothschild, Wisconsin March 28, 2016. REUTERS/Mark Kauzlarich

Republican U.S. presidential candidate Ted Cruz is joined by former Republican presidential candidate and recently announced supporter Carly Fiorina at a press conference after a Cruz town hall event at the Faith Assembly of God in Orlando, Florida March 11, 2016. REUTERS/Kevin Kolczynski

Republican U.S. presidential candidate Ted Cruz and former Republican presidential candidate Carly Fiorina pose for photos after she endorsed Cruz at a campaign rally in Miami, March 9, 2016. REUTERS/Carlo Allegri

HOUSTON, TX - MARCH 15: Carly Fiorina speaks at a watch party for Republican presidential candidate Sen. Ted Cruz (R-TX) on March 15, 2016 in Houston, Texas. Cruz is in a tight race with Donald Trump in the Missouri GOP primary, while Trump took Florida, North Carolina, and Illinois. Gov. John Kasich won his home state of Ohio. (Photo by Bob Levey/Getty Images)

"This is the height of political correctness," Cruz said. "Frankly, the concern is not the Caitlyn Jenners in the world. But if the law is such that any man if he feels like it can go in a women's restroom and you can't ask him to leave, that opens the door for predators."

Host Jake Tapper pushed back, saying that the law would not make it any easier for male predators to go into female restrooms.

"I don't think that's what the law is," Tapper said. "You and I don't identify as female. You and I aren't transgender. This law wouldn't be about you and me going to a women's room."

"The law doesn't specify transgender. It's whatever you feel like at the given moment," Cruz responded.

Cruz is one of the only major presidential candidates left in the field who has expressed outright support for North Carolina's law.

Democratic presidential candidates Hillary Clinton and Sen. Bernie Sanders both oppose the law, while the Republican presidential frontrunner Trump argued that he did not support the law because he believed it could be damaging to businesses.