Note that following from third row, the input has 12 ($1 to $12) columns, tab separated. The last line of the file has 16 ($1 to $16) columns, tab separated. ## lines should be ignored.

I want to take $14 of the last line (interval="1960862) only the number (1960862) add to $4 column (161,2194,2848..4729) i.e (161+1960862=1961023,2194+1960862=1963056..) and to $5 column (317,2280,2951..4756) i.e (317+1960862=1961179,2280+1960862=1963142), ignore the last line.