Randomized. 366 pts, positive N1 or N2 nodes after surgery. Randomized to RT 60 Gy vs no further therapy. Field included bronchial stump, ipsilateral hilum, and most of the mediastinum; included SCLV for pts with upper mediastinal node involvement; mediastinum down to diaphragm for lower lobe primary.

Toxicity: Myelosuppression, alopecia, and fatigue more frequent in cisplatin/docetaxel group, but skin toxicity, liver dysfunction, and diarrhoea more frequent in the gefitinib group. Two patients (2%) developed interstitial lung disease

Conclusion: Patients with EGFR mutations have longer PFS on gefitinib than on cisplatin/docetaxel