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Lumps associated with various forms of arthritis are most likely to develop around the knees, explains Healthgrades. Depending on the cause of a leg lump, people may experience symptoms such as bruising, pain, swelling, redness, fever, weakness, muscle weakness and weight loss. Additional symptoms include bleeding, pus, warmth, joint deformities and discharge. There are cases when symptoms can signal a medical emergency, such as extreme pain, a fever above 101 degrees Fahrenheit, paralysis, broken bones, cold feet, hemorrhaging or a weak pulse.

It is important to see a doctor about any suspicious lumps on the legs and undergo a thorough examination of the area. Doctors should question patients about their medical history and gather detailed information regarding all symptoms associated with the lump. Patients are likely to answer questions about when the lump first appeared, whether there is any pain associated with it, if the lump was caused by an injury and whether it has grown since it first developed. These questions help doctors to accurately diagnose the condition and develop an effective treatment plan, explains Healthgrades.