Defeating Drek

When Ratchet and Clank set off to stop Chairman Drek from destroying planets for his new world, he brought his OmniWrench 8000 with him and used it as a weapon. He also used it to get into new areas by turning bolt cranks and going down ziplines.

Bogon galaxy

Ratchet found wrenches in galaxies without Gadgetron's presence, such as the Bogon galaxy. Ratchet initially carried his OmniWrench 8000, although during his time in the Bogon galaxy he replaced it with more powerful wrenches that he came across. These were the OmniWrench 10000 on Tabora and then the OmniWrench 12000 on Aranos at the Flying Lab, where they were prisoned.

Return to Solana

Ratchet continued to use the OmniWrench 12000 after he returned to Solana. The Wrench's power, while initially weaker than it was in the Bogon Galaxy, was upgraded as Ratchet's maximum nanotech level increased. The power of the wrench was shown visually by the "air swipe" effect when performing a Multi-strike, and when the highest maximum nanotech level was earned in the game (200 nanotech), it was shown by the Hyper-strike as well.

In addition to this, the Wrench could be temporarily enhanced further by destroying Infernox Crates, activated the Infernox wrench effect, which 1-hit KO'd any non-boss enemy it touched, setting fire to them in the process. The Infernox wrench effect was disabled when a boss battle began.

The Shadow Sector

In the Shadow Sector Ratchet acquired a series of new, progressively stronger upgrades for his OmniWrench 12000 thanks to Vox Industries's DreadZone vendors. These were the Versa-Wrench Lite, Versa-Wrench Multicore, Versa-Wrench Striker, Fission Lance and Obsidian Blade. Ratchet then acquired further upgraded versions of the Obsidian Blade as he continued to compete in DreadZone.

Otto Destruct and the Technomites

Ratchet acquired an OmniWrench 10K that could be upgraded using Wrench Mods. By upgrading it in this way it could gain new abilities that harmed enemies in different ways. He used this wrench when he encountered the Technomites.

Stopping Tachyon

Later after leaving the Shadow Sector, he replaced his Dreadzone wrenches with the OmniWrench 3000, an older model of the OmniWrench. He used this in the same way as his original OmniWrench 8000.

Search for Clank

While separated from Clank, he replaced it with the OmniWrench Millennium 12. Ratchet also added an illegal kinetic tether mod to this wrench. This was used for grabbing objects that were out of reach.

Ratchet also indeed used this wrench in his adventure to find Clank and defeat Dr. Nefarious once again in A Crack in Time. The wrench worked different to how it did in Ratchet & Clank Future: Quest for Booty, however, as now it was able to take things out (pulling out objects) rather than move them. He can also not move around when using the Kinetic tether.

Ratchet & Clank: Full Frontal Assault

Ratchet & Clank: Into the Nexus

During the Nether crisis, Ratchet continued to use the OmniWrench Millennium 12. Like before, he does not use the kientic tether attachment.

Non-canon

PlayStation Move Heroes

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Ratchet also uses the Omniwrench 3000 in PlayStation Move Heroes, the reason for this is probably because all of the Ratchet & Clank things in the game were based on their appearance in Tools of Destruction, there was also an exploding OmniWrench.

Playstation All-Stars Battle Royale

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Ratchet uses the OmniWrench Millennium 12 as a melee weapon. His abilities with it are the hyper strike, the multi strike and the comet strike.

Uses

Wrenches could be used for a variety of tasks. As a tool they could be used to tighten bolts and help in the repair of vehicles. With a box breaker, a hyper-strike with a wrench would break any nearby breakables. A comet-strike could be used to destroy explosive crates from a safe distance. They could also be used to turn Bolt Cranks and, as they were magnetized; they could be used to collect bolts from afar.[4] As a weapon, wrenches were used to strike enemies with. This was handy if the user had run out of ammo in their other weapons. The Omni-Wrench Millennium 12 could be used to pick up items such as Lava Rocks. Wrenches could also be used to travel down zip lines.

Modifications

With various mods they could also complete a variety of other tasks. The kinetic tether allowed objects to be manipulated from a distance and spring-like pads to be loaded. The OmniWrench 10K had a variety of mods that could be equipped to give the wrench different abilities including giving out acidic sludge and freezing enemies.

Moves

Performing certain moves with a wrench allowed different amounts of damage to be dealt. A hyper-strike involved jumping up in the air and slamming the wrench back down; this dealt twice as much damage as a regular strike. A multi-strike was a combination of three regular strikes; it gave out double damage on the final strike. A comet-strike allowed the user to attack enemies with wrench from afar; this also allowed several enemies to be easily hit with one strike.

Trivia

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Despite being Rachet's signature weapon with him holding it most cutscenes and promo's the Wrench is used very little in game play due to the lack of upgrades for it in most games in the series.

The names of the two wrench upgrades in Going Commando were never explicitly stated in the game; however, the official Going Commando strategy guide referred to them as the OmniWrench 10000 and OmniWrench 12000. In Up Your Arsenal Ratchet used the second wrench upgrade and it was called the OmniWrench 8000 in the Help Menu, which suggests that the wrenches were newer versions of the original OmniWrench 8000.

Confusingly, although Ratchet's wrench in Size Matters was called the OmniWrench 10K, it resembled his standard OmniWrench 8000 from the first game.