Microbial adaptation to degradation of natural and synthetic organo halogens: Effects on ecosystem acclimation and natural bioremediation of polluted sites

Projektdetails

Gesamtkosten:

EU-Beitrag:

Koordiniert in:

Thema(en):

Finanzierungsprogramm:

CSC - Cost-sharing contracts

Ziel

The project approach is to carry out laboratory research aimed at establishing the relationship between dehalogenation mechanisms for natural and synthetic organohalogen compounds. Subsequently, it will be investigated which genetic processes (mutation, genetransfer) occur during adaptation under selective conditions, and how these processes are influenced by environmental conditions. The activities include: -isolation of organisms that degrade halogenated substrates, using as inocula samples obtained from unpolluted areas and contaminated sites -physiological and biochemical studies to determine dehalogenation and halogenation mechanisms in newly isolated strains -analysis of the genetic organization of organisms that degrade xenobiotic halogenated compounds -examination of genetic processes that occur in chemostats or biofilm systems and that lead to an expansion of the substrate range of the organisms. Organisms known to degrade natural or synthetic gene transfer and adaptation of the community will be established -testing the effect of environmental conditions on the development of dehalogenating organisms and community adaptation, and establishing the relevance to bioremediation strategies.