We studied the influence of highly dispersed copper particles on the metabolism of broiler chicks after a single intramuscular injection. Preparations containing of copper nanoparticles, agglomerates of nanoparticles of copper and copper microparticles were used in the experiment. Intramuscular injections of copper nanoparticles stimulate growth and metabolic changes quickly. Nanoparticle agglomerates and microparticles promote the similar effect but it is extended. The maximum difference in live weight was observed on the fourth day following injection of copper nanoparticles. The injection of copper nanoparticle agglomerates was accompanied by a significant increase in live weight 7 days after injection. The preparation containing copper microparticles had the smallest effect on growth. These changes were observed 16 days after microparticle injection. Copper nanoparticles a day after injection promoted increase in red cell level, hemoglobin, copper and protein in blood serum. Copper nanoparticle agglomerates and microparticles changed protein and copper content in blood serum only 7 and 21 days after injection. Copper microparticles had prolonged effect. The copper preparations promoted an increase in the arginine content of the chicken liver. The results of studies can be used to improve microelement preparations.
Source