““Headache patients everywhere lost an ally and advocate re

““Headache patients everywhere lost an ally and advocate recently with the passing of Dawn A. Marcus, MD . Dawn was born on July 13, 1961. She completed

her medical education at the State University of New York at Depsipeptide datasheet Syracuse in 1986, where she met her future husband, Richard. Over the next several years they welcomed to their family two sons, Steven in 1989 and then Brian a year later. After medical school she completed a transitional year at St. Joesph’s in Syracuse waiting for Richard to graduate. They then moved to Pittsburgh when she completed her residency in Neurology and Richard in Nephrology. In 1990 she joined the faculty at the University of Pittsburgh, most recently achieving the rank of Professor in the Department of

Anesthesia. Since joining the faculty at UPMC she authored over 100 articles and nine books on headache, chronic pain and her most recent http://www.selleckchem.com/products/cobimetinib-gdc-0973-rg7420.html interest, therapy dogs. Dr. Marcus was the 2002 National Headache Foundation Lectureship Award recipient and the 2007 Excellence in Media Award. In 2013 she was named one the top 10 social–health makers for driving the online conversation on migraines and headaches. Dawn’s physical presence left us on October 19, 2013. She is survived by her loving husband of 28 years Richard and her sons, Steven and Brian. She was also the alpha female for her precious Wheaton terriers Wheatie and Toby. Dawn’s family asked that any remembrances be contributed to the Canine Support Team’s Pawz for Wounded Veterans,

P.O. Box 891767, Temecula, CA 92589-1767 orwww.caninesupportteams.org. Supporting Information ““Butalbital is a barbiturate, most frequently prescribed in combination with acetaminophen or aspirin, and caffeine, for the treatment of migraine and tension-type headaches. Its use has waned over the years, in part because so many Amrubicin better remedies are available, and in part because of its reputation for habituation, rapid development of medication overuse headache, and a potentially fatal withdrawal syndrome. This issue of Headache presents a case-controlled analysis of the associations between butalbital and a range of specific birth defects, mining data from the National Birth Defects Prevention study, which evaluates major birth defects across 10 states. Despite an analysis of 8373 unaffected controls and 21,090 case infants, it is an encouraging sign that only 73 case mothers and 15 control mothers reported periconceptional butalbital use. Of the 30 birth defect groups analyzed, statistical significance was found for 3 congenital heart defects: tetralogy of Fallot, pulmonary valve stenosis, and secundum-type atrial septal defect.[1] The study is important despite its being underpowered by the lack of pregnant women using this barbiturate. Unfortunately, this medication is still a go-to drug for many prescribing doctors who mistakenly view it as safer than other alternatives.