Hi all, I have PCOS, this is my first Femara (actually Letrozole) cycle, 13th cycle of TTC though. My doctor told me if I didn't get a positive OPK by CD 16 to come in for an ultrasound. So we did the ultrasound on CD 17 and she told me that I had about 10 follicles on each ovary and she measured at least three or four that were 10 mm on each side.

She told me that since there wasn't a dominant follicle by now that I would not ovulate this month. So I asked if we could up the dosage for next month and she said that since I over responded with so many follicles that she was too nervous of OHSS and HOM so we would do another round of 2.5 mg Letrozole for days 3-7.

How can I have not responded but over responded at the same time? Has anyone had around six 10 mm follicles this late in the cycle and still have one be dominant and ovulate later? Should I keep taking OPKs or is it a waste? I'm so confused! Thanks in advance for your opinions.

I have no experience with Femara or Clomid but I do have experience with similar drugs(injectables)GonalF,Menopur etc,I believe ur doc is right the risk of OHSS is huge!!If you and ur doc decide to up the dosage or change meds I highly recommend the ones I used,no side effects no nasty symptoms but they are a bit pricey,make sure you have constant monitoring!listen to ur doc and try onother round his/hers way I you feel you get no where then I would find onother good doc go listen to my opinions!

My Ovulation Chart . Me 29DH 31After 3 years in which we tried everything we are doing IVF in Greece with Iakentro Athens.Short Protocol with Bemfola and Cetrotide19mature eggs and we have 9 day5 blasto.FET#1 ended in a very early loss,chemical pregnancy.FET#2 ended in a loss at 22w due to IC,my boys will be forever in my heart .FET#3 MMC at the 10 weeks ultrasound.FET#4 2018

Danaa wrote:I have no experience with Femara or Clomid but I do have experience with similar drugs(injectables)GonalF,Menopur etc,I believe ur doc is right the risk of OHSS is huge!!If you and ur doc decide to up the dosage or change meds I highly recommend the ones I used,no side effects no nasty symptoms but they are a bit pricey,make sure you have constant monitoring!listen to ur doc and try onother round his/hers way I you feel you get no where then I would find onother good doc go listen to my opinions!

I agree about the risk of OHSS and we will definitely follow protocol about that. I'm mostly curious about whether I could ovulate later this cycle. My doctor said no but before this cycle, I have ovulated as late as CD 28 before on unmedicated cycles.

Yes you could O later!!Why not the follies are still there,continue with opk's!

My Ovulation Chart . Me 29DH 31After 3 years in which we tried everything we are doing IVF in Greece with Iakentro Athens.Short Protocol with Bemfola and Cetrotide19mature eggs and we have 9 day5 blasto.FET#1 ended in a very early loss,chemical pregnancy.FET#2 ended in a loss at 22w due to IC,my boys will be forever in my heart .FET#3 MMC at the 10 weeks ultrasound.FET#4 2018