Application Information: Acrolein antibody

ELISA: Use at a dilution of 1/2000 - 1/5000. Optimal dilutions/concentrations should be determined by the end user.

Concentration

1
mg/ml
(Please refer to the vial label for the specific concentration)

Purification

Immunogen affinity purified

Specifications: Acrolein antibody

Product Description

Rabbit polyclonal to Acrolein

Background

Acrolein, a reactive alpha,beta-unsaturated aldehyde, is a common environmental pollutant, a metabolite of the anticancer drug cyclophosphamide, and a byproduct of lipid peroxidation. An increase in acrolein production has been proposed as a marker for Alzheimer's disease, diabetic glomerular lesions, and atherosclerosis. Acrolein is a potent inhibitor of cell proliferation at nonlethal doses and may act through effects on redox-regulated transcription factors. It has been reported that NF-kappaB activation is inhibited by acrolein.