Pharmacogenetic testing for allopurinol hypersensitivity is beneficial in select groups

KEY POINT

Testing for the human leukocyte antigen HLA-B*5801 allele before initiating allopurinol was found to be cost effective for black and Asian patients but not for white or Hispanic patients, according to results of a cost-effectiveness analysis published in Seminars in Arthritis and Rheumatism.

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