Myocardial disease

Damage to the
heart muscle most often develops from coronary artery disease (CAD) related
myocardial infarction, usually in people in their middle or later decades. Inherited forms of heart muscle disease
(Cardiomyopathies) are the most prominent cause of myocardial disease in the
young. Myocardial infarction and
cardiomyopathies are the major causes of heart failure and arrhythmic sudden
death. We undertake translational
research focused on determining those at risk (genomics), with an aim of
preventing or minimizing myocardial damage by early disease recognition and
treatment with techniques such as ischaemic preconditioning. Arrhythmia and heart failure research is
concentrated on implementation of new treatments, development and trials of
novel device therapies, and the assessment of ‘improvements’ in healthcare
delivery.