In an Alternate Universe set in the present, celebrity worship has reached its logical end: clinics now harvest diseases from the famous, dilute their infectiousness, and sell them to their fans. The success of the Lucas clinic hinges on their exclusive contract with starlet Hannah Geist (Sarah Gadon) - who is also the object of obsession of Lucas sales rep Syd March (Caleb Landry Jones). Unknown to anyone else, March has not only been shooting himself up with celebrity germs on the sly, he's also been sneaking said germs out of the lab and passing them on to bootleggers. His scheme begins to unravel when, after illicitly sampling Hannah's latest disease, March suffers an extreme, hallucination-fueled reaction, and finds himself the pawn of rival clinic owners and back-alley genetic scientists.

Celeb Crush: It's insinuated that much of the world has one on Hannah Geist.

Copy Protection: Lucas brags that his clinic's method of coding each customer's DNA into the celebrity disease prevents it from infecting others, either accidentally or deliberately. Subverted by Syd, whose home DNA sequencer lets him crack the copy protection and sell the diseases to black marketeers.

Deliberately Monochrome: Of the "Limited Palette" variety. Most of the sets (the Lucas Clinic, Syd's apartment) are all white, and Syd and the other sales reps wear black suits and ties with white shirts. Only in the "real world" - e.g. Hannah's hotel, Dr. Abendroth's country mansion - is a full (if subdued) color palette utilized.

Determinator: Syd, who ends up with a flu modified to cause hemorrhagic fever symptoms and hallucinations, keeps going no matter how many times he is beaten or collapses.

Girl in a Box: Hannah becomes this in the last scene, being kept just alive enough to harvest her cells and virii.

Hemo Erotic: The film ends with an extreme close-up of Syd slicing Hannah's arm with a scalpel and lovingly drinking her blood.

Kubrick Stare: Syd does this on the cover and throughout most of the film.

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