We are testing Ants profiler 8 to see is upgrade is posible.
I start Ants from VS2010, and select profiling on line level mode. Soon after the program to profile starts, it fails with a buffer overrun exception in msvcr100_clr0400.dll.
When running our program without profiling, we do not have any problems.

With our current Ants version 6, we have the same problem, although I do not know if it is a buffer overrun there as well.
The current version of our porgram uses .Net 4.0.
Our previous version used .Net 2.0, and with that version we have no problems profiling. But there have been a lot more change than only switch from 2.0 to 4.0, so I am not sure this is the deciding factor.

For the test I used the newest Ants 8 - 8.3.0.8 - running on Windows XP with sp3 and all the last updates.