An early report from German public TV said 25 people were injured in the incident. But it's not clear if any of the injured were shot, or were hurt in other ways.

Beuth said police received a report about four shots fired.

"There were hostages in the vicinity of the individual. It was at this point that he was fatally shot by special forces," he said. "I have no knowledge that anyone else was harmed."

The U.S. Embassy in Germany said officials are looking into the possibility that tear gas might have caused some of the injuries among the people who were hurt, spokeswoman Jackie McKennan said.

The cinema is part of a major shopping center, home to more than 100 businesses. The Rhein Neckar Zentrum Vienheim shopping complex hosts 20,000 visitors daily, according to its website.

"This (police) operation is now finished," the shopping center said on its Facebook page. "At this moment in time we have no information on injured persons. The driveway is still blocked. We will keep you updated on new developments. "

While the motive for Thursday's attack remains unclear, police have repeatedly warned that Germany could be targeted by ISIS.

Germany absorbed more than 1 million refugees last year, and there have been concerns about the possibility of ISIS cells in the country.