From 1987 to 1994, Michelinie wrote the The Amazing Spider-Man series which featured the art of Todd McFarlane, Erik Larsen, and Mark Bagley, while introducing the supervillainsVenom in issue #298 (March 1988)[16] and Carnage in #361 (April 1992).[17] Michelinie had planned to introduce Venom earlier and included a "teaser" scene in Web of Spider-Man #18, in which Peter Parker is pushed by an offscreen Venom into the path of an oncoming train, the symbiote being immune to Spider-Man's "spider sense" that would have normally warned him of the attack. This was the first of what was to be several clues leading to the reveal of Venom. Michelinie left Web of Spider-Man shortly after and was not able to continue the introduction of Venom until his time of writing The Amazing Spider-Man.

Michelinie returned to comics by teaming-up with Bob Layton and Dick Giordano to form Future Comics. The company closed in 2004. In 2008, he and Layton collaborated again for a four-issue Iron Man: Legacy of Doom miniseries and Iron Man: The End #1 one-shot for Marvel Comics.

^McAvennie, Michael; Dolan, Hannah, ed. (2010). "1970s". DC Comics Year By Year A Visual Chronicle. London, United Kingdom: Dorling Kindersley. p. 163. ISBN978-0-7566-6742-9. David Michelinie's pen and Ernie Chan's pencils and inks provided the magic for this fantasy series that introduced Claw the Unconquered, a barbaric outlander with a deformed claw-like right hand.

^McAvennie "1970s" in Dolan, p. 175: "The Sea King's fans were thrilled to see their hero resurface in his own title...Scribe David Michelinie and artist Jim Aparo chronicled Aquaman's [adventures]."

^Sanderson, Peter; Gilbert, Laura, ed. (2008). "1970s". Marvel Chronicle A Year by Year History. London, United Kingdom: Dorling Kindersley. p. 187. ISBN978-0756641238. Writer David Michelinie and inker Bob Layton began their classic run co-plotting The Invincible Iron Man with issue #116.

^Sanderson "1970s" in Gilbert (2008), p. 187: "In December [1978], co-plotters David Michelinie and Bob Layton, and penciler John Romita, Jr....came up with Bethany Cabe, a highly capable professional bodyguard and a different sort of leading lady."

^Sanderson "1970s" in Gilbert (2008), p. 188: "Writer David Michelinie and artists John Byrne and Bob Layton introduced James Rhodes Tony Stark's best friend and future super hero War Machine in The Invincible Iron Man #118."

^Sanderson "1970s" in Gilbert (2008), p. 189: "Tony Stark's billionaire nemesis Justin Hammer made his first appearance in The Invincible Iron Man #120 by writer David Michelinie and artist John Romita, Jr. and Bob Layton."

^DeFalco, Tom "1980s" in Gilbert (2008), p. 233: "Although actually called 'Stark Wars', the story arc that became known as 'Armor Wars began in [Iron Man #225] and ran until June 1988."

^DeFalco "1980s" in Gilbert (2008), p. 197: "Created by writer David Michelinie and artist George Pérez, Taskmaster could mimic any physical skill he had ever seen."

^Manning, Matthew K.; Gilbert, Laura, ed. (2012). "1980s". Spider-Man Chronicle Celebrating 50 Years of Web-Slinging. London, United Kingdom: Dorling Kindersley. p. 169. ISBN978-0756692360. In this landmark installment [issue #298], one of the most popular characters in the wall-crawler's history would begin to step into the spotlight courtesy of one of the most popular artists to ever draw the web-slinger."

^Cowsill, Alan "1990s" in Gilbert (2012), p. 197: "Artist Mark Bagley's era of The Amazing Spider-Man hit its stride as Carnage revealed the true face of his evil. Carnage was a symbiotic offspring produced when Venom bonded to psychopath Cletus Kasady."

^Manning, Matthew K. "1990s" in Dolan, p. 259: "Writer David Michelinie and artist Sal Velluto introduced a different type of Justice League in their new ongoing series ''Justice League Task Force."

^Manning "1980s" in Gilbert (2012), p. 164: "Plotted by Marvel Editor-in-Chief Jim Shooter and written by David Michelinie with pencils by Paul Ryan, this issue wasn't the standard wedding comic fare."