Search for Luxury hotels in San Francisco

Top San Francisco neighborhoods

South of Market

Once the center of the dotcom bubble, South of Market, just south of downtown San Francisco, still supports some tech companies, but nowadays has a more eclectic atmosphere. It’s full of art galle…

Once the center of the dotcom bubble, South of Market, just south of downtown San Francisco, still supports some tech companies, but nowadays has a more eclectic atmosphere. It’s full of art galleries and museums - the SOMArts Cultural Center is one of the most innovative. Catch a baseball game if the Giants are home, or look out over the beautiful San Francisco Bay at the natural Bay Front Park.

Financial District - Ferry Building

The heart-racing epicenter of business in San Francisco, the Financial District has a stunning skyline of gleaming high-rises – the Transamerica Pyramid is an icon of the city. All of this gives w…

The heart-racing epicenter of business in San Francisco, the Financial District has a stunning skyline of gleaming high-rises – the Transamerica Pyramid is an icon of the city. All of this gives way to the palm-trees of the Embarcadero, an epic avenue that gives you perfect views of San Francisco Bay. Take a walk down to the Beaux Arts-style Ferry Building, which houses cool cafes and an artisan food market.

Fisherman's Wharf

The most exciting waterfront district in San Francisco, Fisherman's Wharf is home to Pier 39, where sea lions flap happily about in the sun while visitors chow down on chowder, look at the sharks …

The most exciting waterfront district in San Francisco, Fisherman's Wharf is home to Pier 39, where sea lions flap happily about in the sun while visitors chow down on chowder, look at the sharks in the Aquarium of the Bay, and hop on amusement rides. Mingle with the surging crowds amid the restaurants of Ghirardelli Square, or wander over to Hyde Street Pier to see the historic ships anchored there.

Hotel types

Explore San Francisco

Luxury San Francisco hotel, United States of America Spoil yourselves on your next holiday by booking a Luxury San Francisco hotel with Hotels.com. Thanks to our comprehensive online hotel directory you can search through all of our Luxury San Francisco hotels and compare their room rates to find the right one for you. All you have to do is:

Popular with travelers from US

Luxury hotels in San Francisco

Most recent review

"Weather was horrible! My little family and I spent the night here. It was very comfortable and the people were very nice! However, there are four different charges to my card I still need to figure out why! We only stated there for 8 hour. Slept showered and left!"

Most recent review

"Loved the hotel and the location. I was a little concerned by reviews that said there were a lot of homeless in the area but I didn't see an exceptional amount. Just one or two here and there, which comes with SF. Other than that the service, room and everything about the hotel was so comfort..."

Most recent review

"Very nice hotel. The entrance is very hard to find. Staff that helped us was not helpful and not as friendly as I would expected for this price range hotels. They didn't offer bell service until I asked also when I asked for a room at different level, staff told us that she's going to che..."

Most recent review

"The hotel was beautiful and had fantastic service! It was also next-door to a number of restaurants and a mall including a Target. It's not the most artistic area of San Fran, but the hotel was great!"

Most recent review

"Booked the Mandarin Oriental for one night for a layover to Hawaii for our Anniversary trip. I wanted something special since we were only in SanFran for one night. Wow! The view was spectacular. But...to make it even better, the hotel sent up a bottle of champagne and chocolate dipped strawberri..."