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Malaria

Malaria research has a significant role in the Broad Infectious Disease Program, and its scope and impact at the institute is currently in a phase of considerable growth.

Research in malaria reaches across the Broad, leveraging the Institute’s unique resources — its platforms and its people — to fill significant gaps in our understanding of malaria biology and to tackle critical roadblocks on the path to disease control. Key areas of focus in malaria research at Broad include:

Understanding the nature and impact of genetic diversity in malaria parasites and their vectors.

Using nanotechnology to unlock the elusive liver stage infection.

Using stem cell and RNAi technologies to understand the role of the host red cell.

Using a variety of genomic, chemogenomic and proteomic approaches to identify novel drug and vaccine candidates.

Broad malaria researchers also work closely with colleagues at affiliated institutions and across the globe — particularly through the Harvard T.H. Chan School of Public Health — to address this global health threat through close collaboration.

In keeping with the Broad mission, tools and data that grow out of this research are shared openly with the global malaria research community.