Patients who sign and date a Patient Informed Consent prior to study enrollment

Patients who remain in the clinical care of physicians of their implanting center

Exclusion Criteria:

Patients who have chronic atrial fibrillation. Paroxysms of AF are not an exclusion criterion, but the patient must be in normal sinus rhythm at the time of randomization. If history of AF is unknown or uncertain, or the patient was recently cardioverted, there must be at least 23 hours of normal sinus rhythm within the 24 hour period preceding randomization

Patients who previously had an ICD

Patients with current indications for cardiac resynchronization therapy with defibrillation (CRT-D)

Patients whose life expectancy is less than 12 months due to other medical conditions

Patients who are expected to receive a heart transplant during the duration of the study

Patients who have or who are likely to receive a tricuspid or other valve prosthesis

Patients who are currently enrolled in another investigational study of active medical therapy. Each instance should be brought to Guidant’s Clinical Application Research Studies (CARS) group to determine eligibility

Patients who are younger than 18 years of age

Patients who are mentally incompetent and cannot give a Patient Informed Consent or participate in the study

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00158912