Levallofano [Dcit]
H2O Solubility

Levallofano [Dcit]
State

Levallofano [Dcit]
LogP

Levallofano [Dcit]
Dosage Forms

Levallofano [Dcit]
Indication

For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids.

Levallofano [Dcit]
Pharmacology

Levallorphan, an opioid antagonist similar to naloxone, is used to treat drug overdoses. Levallorphan differs from naloxone in that it also possesses some agonist properties. It is an analogue of levelorphanol that counteracts the actions of narcotic analgesics such as morphine. It is used especially in the treatment of respiratory depression due to narcotic overdoses. Levallorphan prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Also, it can reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine.