The reason is that the big drug companies do not put their publicity machine behind studies that call into question the safety or healthfulness of their blockbuster drugs. And that is exactly what this study did.

Simvastatin is Zocor. What this small but interesting study found was that "Simvastatin significantly improved endothelium-dependent dilation, but reduced adiponectin levels and insulin sensitivity in hypercholesterolemic patients independent of dose and the extent of apolipoprotein B reduction."

Translated into English this means that Zocor reduced cholesterol and improved the elasticity of arteries, but did this at the cost of increasing insulin resistance and decreasing the hormone, adiponectin, that keeps people from gaining weight.

Can this be yet another reason for the so-called "Diabetes Epidemic?" It would be ironic if the overprescribing of statins to people with mildly elevated cholesterol turns out to be a major factor in worsening blood sugars.

We know that giving statins to people who don't already have heart disease does very little to improve health. But we also know that raising blood sugar by the amount needed to raise A1c by as little as 1% (i.e. from 4.7% to 5.7%) is enough to create a very significant increase in heart attack risk.

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More evidence that the value of statins should not be taken at face value alone. Perhaps a few years from now, we'll look back at this and ask ourselves "what were we thinking when we said statins should be prescribed to everyone -- especially those with diabetes?".

Until then, I think there needs to be more solid evidence of their value, and that, too, seems to be in short supply.

Do I have this right: Statins increase 'elasticity' of the arteries; insulin use (or more aptly, increased insulin use) 'hardens' the arteries. Statins (may) promote increased insulin use by inducing insulin resistance. Looks like a pretty profitable situation for BigPharma. They profit by selling statins; they profit by increasing insulin usage. And perhaps the best a diabetic can hope for, in the end, is "a wash" . . .

My doctor recently insisted that I start taking statins immediately simply because I have diabetes. I refused. I had made some big changes in my diet and management plan with the goal of increasing my insulin sensitivity and she hadn't even seen my current lab results. And as it turns out my cholesterol levels had dropped nearly 100 points and there was no need for the medication. She's no longer my doctor.

I get very tired of arguing with doctors about what drugs I'm willing to put in my body--and which ones I'm absolutely not.

Wow! I'm a T2 on meds, including Lipitor. I was asked to go from 20 mg to 40 mg of this statin, due to elevated levels of CRP. And I have gained 15 lbs. My insulin resistance is such that I am now to begin Byetta at my next appt (June '08). I have a reknowned endocrinologist (Nathan Becker of UCSF), so I will certainly be asking him about the relationship between my statin and my FAT ***!

Big News! (NBC Nightly News, July 7, 2008): Big Pharma is now targeting our kids for "Preventative" statin therapy--they suggest statin therapy for children as young as two years old.What a bonanza for Big Pharma! Imagine the consequences of all that potential for increased insulin resistance, congestive heart problems, worsening sugar levels, muscular weakness etc. Why is out major news media so unwilling to do some investigative reporting and challenge all this nonsense?

I found a way around the "Fat" problem with statins. Of course, what works for me may not work for you. Ask your doctor. The secret? Breakfast: 2 ounces of whole grain bread dipped into ione tablespoon cold pressed olive oil-- about twenty fresh grapes-- four figs--and one other fruit and a one ounce serving of cheese. This combo depresses appetite for almost the entire day and at noon, have a salad with another TBSPN olive oil. I lost six pounds the first week on this. (Include one regular moderate-sized meal of about 400 to 500 calories. It has been a miracle for me.

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I was diagnosed with diabetes in 1998. Since then I've kept my A1cs in the 5.0-6.0% range using the techniques you'll find explained at The main Blood Sugar 101 Web Site, where you'll also find extensive discussion of the peer-reviewed research that backs up the statements you read here.

I've also published two books on related subjects, Blood Sugar 101: What They Don't Tell You About Diabetes, which was an Amazon Diabetes bestseller for 3 years and Diet 101: The Truth About Low Carb Diets.