2015-01-31T17:29:06ZDissension within the Confederacy : the Tenth Legislature of Texas during the U.S. – C.S. War.http://hdl.handle.net/2104/9223
Dissension within the Confederacy : the Tenth Legislature of Texas during the U.S. – C.S. War.
At the time that Texas’ Tenth Legislature began their session in the autumn of 1863, the war between the United States and the Confederacy was in its third year. The Eighth and Ninth Legislatures worked to respond to the necessities of the state during the outset and first years of the war, often putting the war effort and the needs of the Confederacy first. Various issues such as state finances, state defense, and frontier protection demanded action. After the summer of 1863, as the war shifted in favor of the North, the newly elected legislature and new governor began to put the needs of Texas first. This caused some dissension between the state and the Confederate government.
2014-10-29T00:00:00ZEvaluation of resurgence after functional communication training of two communication responses.http://hdl.handle.net/2104/9202
Evaluation of resurgence after functional communication training of two communication responses.
Zoch, Tamara L.
The current study examined the effects of multiple evaluations of resurgence of challenging behavior. A functional analysis identified the function of participants' challenging behavior. Participants were taught two alternative communication behaviors that served the same function as the challenging behavior. After the participants were taught the first communication behavior, a test for resurgence was implemented, in which reinforcement was withdrawn for using the alternative communication device. Then, a second alternative communication was taught to the participants and reinforced. Next, reinforcement was available for both alternative communication devices. In the final test for resurgence, neither alternative communication behavior was reinforced. This study used an A-B-C-D-B'-C design to evaluate participant responses.
2014-09-05T00:00:00ZClergy perceptions of sexual assault victimization.http://hdl.handle.net/2104/9201
Clergy perceptions of sexual assault victimization.
Yuvarajan, Elil.
Although congregants often turn to clergy for help in dealing with personal difficulties, including marital problems, substance abuse issues, and mental illness, survivors of sexual assault do not commonly turn to clergy for support or guidance. This study utilized a mixed-methods approach, including an online survey and semi-structured interviews, to look at how clergy perceive sexual assault victimization to discover how those attitudes influence relationships with survivors of sexual assault. The results of the study showed that more blame was assigned to the victim as the relationship with the perpetrator became closer, with the exception of marital rape. The study also found that hostile sexism was a predictor of negative attitudes toward rape victims. Also, religious fundamentalism was not a predictor of negative attitudes toward rape victims. The results of the semi-structured interviews were used to inform the interpretation of the survey results. Clergy reported four main themes that drove their perceptions of sexual assault: the taboo nature of sexual assault, benevolent sexism as a part of church culture, differences in the power hierarchy between clergy and congregants, and the lack of and need for training on working with survivors.
2014-09-05T00:00:00ZThe integrin interacts with cki-1/p27kip1, a tumor suppressor gene, of the nematode Caenorhabditis elegans.http://hdl.handle.net/2104/9200
The integrin interacts with cki-1/p27kip1, a tumor suppressor gene, of the nematode Caenorhabditis elegans.
Yu, Eun-Jeong.
Integrin is a heterodimeric cell surface receptor for extracellular matrix (ECM) and plays essential roles in regulating cell behaviors such as cell migration, adhesion, growth and death. The cell-ECM interaction is particularly important for progression and arrest of cell cycle. However, the mechanism by which the ECM influences the cell cycle in vivo is poorly understood. To study the role of integrin in cell cycle, we generated a pat-3, Caenorhabditis elegans β integrin, transgenic mutant. The pat-3 (sp) carrying a defective splicing of intron 7 displayed growth defective phenotypes such as coldsensitive larval arrest, shorter body length, reduced lifespan, and increased sterility. To study the role of integrin in cell growth, we assessed for the interaction of integrin signaling to CKI-1 that is a C. elegans homologue of the cyclin dependent kinase inhibitor p27kip1, a tumor suppressor. In wild type pat-3 (+), CKI-1::GFP is localized to nucleoli in hypodermis; whereas, CKI-1::GFP appeares clumped and scattered in the nucleoplasm of pat-3 (sp). In addition, the level of CKI-1::GFP protein was found elevated in pat-3 (sp). In an RNAi screen, we found that integrin signaling and SCF E3 ubiquitin ligase genes appeared to involve in the localization and expression of CKI-1. This result suggests that integrin signaling and SCF E3 ligase work together to regulate the cellular distribution of CKI-1. We continued to study the localization of CKI-1 and investigate suppressors of pat-3 (sp) defects. RNAi screen revealed that genes involved in ribosome biogenesis, unfolded protein response, chromatin modification, rRNA processing, and ubiquitin-mediated protein degradation are required for the up regulation of CKI-1::GFP, suggesting that integrin signaling links to the function of many genes acting in nucleus, nucleolus, and protein degradation. My study demonstrated that integrin plays robust roles in regulating the proper localization and level of CKI-1/p27kip1 in concert with integrin signaling, protein degradation, and many nucleus expressed genes including dnc-1, hda-1, mig-32, and lpd- 7. This provides insight into potential molecular mechanism of the mammalian β1 integrin splice variants, β1B and β1C, in regulating cell behavior.
2014-09-05T00:00:00Z