REGISTRATION STATEMENT (811-07239) UNDER THE INVESTMENT COMPANY ACT OF

1940 Amendment No. 54

[X]

VANGUARD HORIZON FUNDS

(Exact Name of Registrant as Specified in Declaration of Trust)

P.O. Box 2600, Valley Forge, PA 19482

(Address of Principal Executive Office)

Registrant’s Telephone Number (610) 669-1000

Heidi Stam, Esquire

P.O. Box 876

Valley Forge, PA 19482

Approximate Date of Proposed Public Offering:

It is proposed that this filing will become effective (check appropriate box)

[ ] immediately upon filing pursuant to paragraph (b)

[X] on October 22, 2012, pursuant to paragraph (b)

[ ] 60 days after filing pursuant to paragraph (a)(1)

[ ] on (date) pursuant to paragraph (a)(1)

[ ] 75 days after filing pursuant to paragraph (a)(2)

[ ] on (date) pursuant to paragraph (a)(2) of rule 485

If appropriate, check the following box:

[ ] This post-effective amendment designates a new effective date for a previously filed

post-effective amendment.

SIGNATURES

Pursuant to the requirements of the Securities Act of 1933 and the Investment Company Act of 1940, the Registrant hereby certifies that it meets all requirements for effectiveness of this Registration Statement pursuant to Rule 485(b) under the Securities Act of 1933 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the Town of Valley Forge and the Commonwealth of Pennsylvania, on the 22nd day of October, 2012.

VANGUARD HORIZON FUNDS

BY:____________/s/ F. William McNabb III*_____

F. William McNabb IIIChief Executive Officer, President, and Trustee

Pursuant to the requirements of the Securities Act of 1933, this Post-Effective Amendment to the Registration Statement has been signed below by the following persons in the capacities and on the date indicated:

Signature

Title

Date

/s/ F. William McNabb III*

Chief Executive Officer,

October 22, 2012

President, and Trustee

F. William McNabb

/s/ Emerson U. Fullwood*

Trustee

October 22, 2012

Emerson U. Fullwood

/s/ Rajiv L. Gupta*

Trustee

October 22, 2012

Rajiv L. Gupta

/s/ Amy Gutmann*

Trustee

October 22, 2012

Amy Gutmann

/s/ JoAnn Heffernan Heisen*

Trustee

October 22, 2012

JoAnn Heffernan Heisen

/s/ F. Joseph Loughrey*

Trustee

October 22, 2012

F. Joseph Loughrey

/s/ Mark Loughridge*

Trustee

October 22, 2012

Mark Loughridge

/s/ Scott C. Malpass*

Trustee

October 22, 2012

Scott C. Malpass

/s/ André F. Perold*

Trustee

October 22, 2012

André F. Perold

/s/ Alfred M. Rankin, Jr.*

Trustee

October 22, 2012

Alfred M. Rankin, Jr.

/s/ Peter F. Volanakis*

Trustee

October 22, 2012

Peter F. Volanakis

/s/ Thomas J. Higgins*

Chief Financial Officer

October 22, 2012

Thomas J. Higgins

*By: /s/ Heidi Stam

Heidi Stam, pursuant to a Power of Attorney filed on March 27, 2012, see File Number 2-11444, Incorporated by Reference.