Other differential factors, such as the presence and composition of an integrative conjugative element associated with the Hrp T3SS ( hrp genes encoding the T3SS apparatus), have been recently described. (mdpi.com)

Here, we describe a protocol for the identification of pathogenicity and virulence genes through random insertional mutagenesis using the fungal wilt pathogen Verticillium dahliae as an example for the protocol. (wur.nl)

Agnoli K, Lowe CA, Farmer KL, Husnain SI, Thomas MS (2006) The ornibactin biosynthesis and transport genes of Burkholderia cenocepacia are regulated by an extracytoplasmic function s factor which is a part of the Fur regulon. (springer.com)

A well established statistical tool known as multivariate linear regression may offer a new approach in determining contributions of multiple virulence factors to the overall virulence of pathogenic microbes say researchers from Albert Einstein College of Medicine, Bronx, New York and Westminster College, Salt Lake City, Utah. (rxpgnews.com)

Although some progress have been achieved on the knowledge of the pathogenesis traits and virulence factors used by these bacteria, further work envisaging the identification of potential targets for the scientifically based design of new therapeutic strategies is urgently needed, due to the very difficult eradication of these bacteria with available therapies. (springer.com)

These factors include polysaccharide capsules and M proteins that impede phagocytosis, enzymes that degrade host tissues, and toxins that overstimulate the immune system, causing fever and shock. (britannica.com)

Functional genomic analysis provided data that allowed us to correlate the highly infectious nature of Aeromonas pathotypes belonging to several different species with virulence signatures and their potential ability to cause NF. (sigmaaldrich.com)

Similar to other Proteus species, P. penneri has a cell-bound hemolytic factor, which has been shown to facilitate penetration of the organism into cultured Vero cells without any cytotoxic effects. (wikipedia.org)

The most virulent strains possessed one of the following four virulence factors or a combination of them: cytotoxic enterotoxin, exotoxin A, and type 3 and 6 secretion system effectors AexU and Hcp. (sigmaaldrich.com)

Multivariate linear regression can be used to identify the relative levels of importance of virulence factors in virulence studies, and this information can be used to prioritize antigen identification for vaccine development and the design of antimicrobial strategies that target virulence mechanisms," say the researchers. (rxpgnews.com)

prfA is thermoregulated by the PrfA thermoregulator UTR element, such that translation of prfA maximally occurs at 37 °C and is nearly silent at 30 °C. Since 37 °C is within the range of normal body temperature, PrfA protein, as well as listeriolysin O and other virulence factors regulated by PrfA, is only produced when L. monocytogenes is in a host. (wikipedia.org)

To investigate the potential role of the Ave1 homologs in virulence, a V. dahliae Ave1 deletion mutant was complemented with the Ave1 homologs of Fusarium, Cercospora and Colletotrichum, and tested for full aggressiveness on tomato. (wur.nl)