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IN THE NEWS • 07/31/2014

News: FDA Approves New CRC Drug for Phase I Clinical Trial

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Exciting news in the colon cancer world! Last week, the experimental drug MGD007 was cleared by the FDA for Phase I clinical trials in colon cancer, scheduled to start later this year. MGD007 is different from other drugs currently available because it kills cancer cells in a different way. Specifically, it binds to a protein on immune system cells (or T-cells) and directs them to kill cells that express a protein found on 95% of primary and metastatic colon cancer cells.

This means MGD007 has the potential to be highly effective in shrinking colon and rectal tumors in much more targeted way and with a lower dosage, so it’s less toxic. Until this point, the drug has been effective on cell lines and in animals; we’re thrilled to see the results on this upcoming Phase I human clinical trial. This data was presented to thousands of medical professionals, researchers and advocates at the 2014 American Association of Cancer Research (AACR) meeting. For more details, take a look at the full release.

Don’t forget, the Colon Cancer Alliance serves as a source of information about colon health. If you have questions or are in need of support, please contact our free Helpline at (877) 422-2030. We’re here to help.

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