Hypoxia is characterized by an inadequate oxygen supply to the tissues in
proportion to their metabolic needs, and is a primary factor in traumatic CNS
injury, strokes, cardiopulmonary diseases, and obstructive sleep apnea. The
cAMP-dependent...

Kentucky is the fifth largest producer of coal ash, a by-product of coal combustion. The small spherical coal ash particles contain heavy metals like arsenic, lead, mercury, and cadmium. Coal ash is currently classified as nonhazardous by the EPA,...

Dermal wounds, including bed sores, pressure ulcers, and diabetic ulcers have a large impact on American healthcare costing up to $7 billion per year. Adequate pharmaceutical remedies applied at constant rate could prove to increase the healing...

Analysis of volatile organic compounds (VOCs) in air and exhaled breath by sensor array is a very useful testing technique. It can provide non-invasive, fast, inexpensive testing for many diseases. Breath analysis has been very successful in...

Development of microscale actuating technologies has considerably added to the toolset for interacting with natural components at the cellular level. Small-scale actuators and switches have potential in areas such as microscale pumping and particle...

The field of bone densitometry has grown rapidly, particularly in the past 15 years. Many techniques are now available from which the physician may choose. The focus of this research is on Dual-Energy X-Ray Absorptiometry (DXA) and Quantitative...

Indices are popular in many sectors of the US economy and are commonly used by businesses when making important decisions. In this research, two new indices are developed; a regional index for the Greater Louisville area and a national index for...

Wind power has the potential to provide access to electricity to areas lacking the resources to create industrial power plants, as well as supplement residential energy supplies. The low resource investment and ease of installation make it ideal...

Meat is a major component of the diet of an American. However, humans do not consume one-third to one-half of each animal raised for their needs. The leftover materials are subjected to processing in the meat rendering industry. The rendering...

Having been born and brought up in China, an empire, where the people are utterly ignorant of the vital importance of a good system of public water supply, and having decided to take chemistry as my profession, I feel intensely interested in the...

This creative thesis follows the opening story arc to a larger fiction project in the genre of high fantasy fiction. Structurally and stylistically, by incorporating contemporary contributions to the genre from Japanese popular culture, this story...

Cardiovascular disease is the leading cause of death worldwide. When a myocardial infarction occurs, scar tissue compensates the damaged myocardial tissue. This scar tissue increases the stiffness of the heart tissue, reduces the heart’s...

Water treatment facilities strive to provide potable drinking water to the community which they service. The most common way of insuring drinkable water that is free of pathogens is water chlorination, but this can lead to the production of...

This investigation was carried out in an attempt to determine the nature of some of the physiological changes,
particularly the shift in the water balance during the rise in temperature following pyretic doses of cocaine. It is
well known that...

High dynamic range imaging involves imaging at a bit depth higher than the typical 8-12 bits offered by standard video equipment. We propose a method of imaging a scene at high dynamic range, 14+ bits, to detect motion correlated with changes in...

This dissertation is about building a Multiple Air Robotics Indoor Testbed (MARIT) for the purpose of developing and validating new methodologies for collaboration and cooperation between heterogeneous Unmanned Air Vehicles (UAVs) as well as...

Crossover design is a type of longitudinal study with each subject receiving different treatments in different time periods. It has been used frequently in the pharmaceutical industry and other medical fields to investigate the safety and efficacy...

Nitrile hydratase (NHase) is a metalloenzyme that contains a non-heme iron (III)
or non-corin cobalt (III) in a non-redox active role. NHase is used as biocatalyst in the
industry for the hydrolysis of nitriles to arnides. The trivalent metal ions...

The Technical Advisory Group (TAG) of the Innovative Treatment Remediation Demonstration Program (ITRD) made technology recommendations after reviewing thirty in situ remediation technologies for implementation at the Paducah Gaseous Diffusion...