Richard Sherman, K.J. Wright sat out Seahawks practice

If the 49ers (0-1) are going to pull of a massive upset Sunday, and win their first game in Seattle since 2011, it might take the Seahawks missing some key players.

All-Pro cornerback Richard Sherman (hamstring) and linebacker K.J. Wright (ankle) sat Wednesday during their first practice of the week ahead of Week 2’s match up with San Francisco.

The severity of their injuries are unknown. Both Sherman and Wright played all 82 snaps during the 17-9 loss Sunday to the Packers. Sherman, 29, has started every game since 2012. Wright, the starting weak side linebacker, hasn’t missed a game since 2013.

Linebacker Terence Garvin (shoulder) also sat Wednesday after being used during 31 snaps in Green Bay.

The 49ers managed just 217 yards of offense in coach Kyle Shanahan’s debut with Brian Hoyer under center against the Carolina Panthers.

San Francisco’s offensive line struggled, allowing four first-half sacks, including a strip-sack which led to the Panthers’ first touchdown of the afternoon. It turned out at that score was all Carolina needed after holding Shanahan’s offense to just a field goal in the 23-3 victory.