Introduction: Job satisfaction and organizational commitment are considered prerequisites of internal and external efficiency of an organization. This study was aimed at investigating the relationship between job satisfaction and organizational commitment of health educators of high schools in Hormozgan Province. Methods: In this descriptive-correlational study with respect to data analysis, 115 health educators in Hormozgan Province were selected through random sampling. The data were collected with job satisfaction and organizational commitment questionnaire. They were analyzed through descriptive statistics and regression methods using SPSS 18. Results: The results showed a significant positive relationship between job satisfaction and organizational commitment components including continuance, affective, and normative commitment (r=0.504). Fifty percent of changes in job satisfaction were affected by organizational commitment. Conclusion: The results of this study indicated that the relationship between job satisfaction and organizational commitment could provide valuable guidance for increasing motivation among health educators and actualizing their potential powers. As an important predictor of organizational commitment, job satisfaction played a significant role in health educators.