New acquaintance John Barrymore (title character) insinuating himself with Roman power player Lucrezia Borgia (Estelle Taylor), having intercepted a chalice she poisoned for his fellow Spaniard, the father of Adriana (Mary Astor), herself falling under his spell, in Don Juan, 1926.>

Adriana (Mary Astor) and father (Josef Swickard) are introduced at the court of the Borgia, (Estelle Taylor, Warner Oland, Montagu Love as Donati) plotting as the title character (John Barrymore) arrives, distracted by a maid (Helene Costello), spied by Maria (Myrna Loy), in Don Juan, 1926.>