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Abstract

We have simulated the photon migration with various source-detector separations based on a three-dimensional Monte Carlo code. The whole brain MRI structure images are introduced in the simulation, and the brain model is more accurate then the previous studies. The brain model consists of scalp, skull, CSF layer, gray matter, and white matter. We demonstrate dynamic propagating movies under different source-detector separations. The multiple backscattered intensity from every layer of the brain model is obtained by marking the deepest layer which every photon can reach. Also the influences of an absorption target on brain cortex are revealed.

Figures (7)

The nine MRI images on the left are corresponding to different depths of the brain. Here, we took 50 images to fill all the voxels. Each MRI image consists of 256×256 pixels. The schematic diagram on the right shows the anatomical structure of the human head.

The movies show the migration of a pulse of light with 800 nm wavelength through a brain structure. Movies are given for (a) the horizontal cross section, (b) the vertical cross section of human head. The sizes of MOV movie files are 2.08 and 1.1 Mega-Bytes, respectively.

The movies show the photon migration of the received photons with different distances of source-detector separation (a) 1 cm (b) 2 cm (c) 3 cm in the horizontal cross section of human head. The sizes of MOV movie files are 0.54, 0.51 and 0.49 Mega-Bytes, respectively.