Haplotype M3, accounted for 66% of male
Y-chromosomes
and was found associated with native populations from the Chukotka peninsula
in Siberia, adjacent to
Alaska. The second major group of Native American Y-chromosomes,
haplotype M45, accounted for about one-quarter of male lineages. This
haplotype was found in the
Lower Amur River and Sea of Okhotsk regions of eastern Siberia. The remaining 5% of Native American
Y-chromosomes
were of haplotype RPS4Y-T, which was found in the Lower Amur River/Sea of Okhotsk
region of Siberia. These data suggested that Native American male lineages were
derived from two major Siberian migrations.1