Synagis Warnings and Precautions

Make sure your child's healthcare provider knows if your child has a bleeding disorder or plans to have heart surgery before beginning treatment with Synagis. Other safety precautions involve warnings of possible drug interactions and allergic reactions. Also, this drug is given by injection, which may cause pain, swelling, and redness at the injection site.

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You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Synagis

Some warnings and precautions to be aware of prior to using this medication include the following:

There have been reports of severe allergic reactions occurring in children receiving Synagis. These reactions can occur after any dose. Seek immediate medical attention if you notice any symptoms of an allergic reaction, such as:

This medication should only be given as an intramuscular injection (an injection into the muscle), usually in the outer part of the thigh.

You may experience mild pain, redness, or swelling at the site of the injection. Contact your healthcare provider if you have a severe or persistent reaction at the injection site.

Synagis comes in single-use vials. The vials do not contain a preservative. Therefore, the injection must be administered immediately after the dose is withdrawn from the vial. Also, any medication remaining after a dose is given must be discarded. It cannot be saved for future use, or used for another dose.

Although this medication is approved to prevent respiratory syncytial virus (RSV), it is unknown whether Synagis is safe or effective in children who already have an RSV infection. However, it is generally recommended that children who develop an infection continue to receive monthly doses.

This product is a pregnancy Category C medication, which means it may not be safe for use during pregnancy (see Synagis and Pregnancy).

It is unknown if this medicine passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to using the drug (see Synagis and Breastfeeding).

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