Hermes-14, and its sister rocket Hermes-13, were planned to be the latest manned mission to the Mars, with an expected launch date of summer, 2078. However, as the war with China intensified, Enclave and Department of Defense agents seized control of the Space Center and tried to retrofit the rockets for travel to B.O.M.B. 002 and another planet, where the American way of life would be preserved.

The mission: have the crew deliver and install the bases' main power reactors, manually enter final launch instructions, manual check for safety nets and protocols, and do a manual inspection of the station.

However, the bombs dropped sooner than expected, and both parties were forced to pull out of the space center, either due to lack of supplies or motivation. The Enclave would need to retake the planet, and the Department of Defense would need to worry about whether they got into the Enclave vaults.