n : an increase in the symptoms of a spirochetal disease (as syphilis, Lyme disease, or relapsing fever) occurring in some persons when treatment with spirocheticidal drugs is started - called also Herxheimer reaction

Jarisch, Adolf (1850-1902), Austrian dermatologist. Jarisch published his description of the Jarisch-Herxheimer reaction in 1895, seven years before Herxheimer published his own description.

Herxheimer, Karl (1861-1944), German dermatologist. Herxheimer published his description of the Jarisch-Herxheimer reaction in 1902. In that same year he also described acrodermatitis chronica atrophicans.