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What are the key statistics about gestational trophoblastic disease?

Gestational trophoblastic (jeh-STAY-shuh-nul troh-fuh-BLAS-tik) disease (GTD) occurs in about 1 pregnancy out of 1,000 in the United States. Most of these are hydatidiform (HY-duh-TIH-dih-form) moles.

Choriocarcinoma (KOR-ee-oh-KAR-sih-NOH-muh), a malignant form of gestational trophoblastic disease (GTD), is even less common, affecting around 2 to 7 of every 100,000 pregnancies in the United States.

Choriocarcinoma and other forms of GTD are more common in many Asian and African countries.

Overall, gestational trophoblastic tumors account for less than 1% of female reproductive system cancers.