- No other malignant disease apart from non-melanotic skin cancer or carcinoma in situ of the uterine cervix or any other cancer treated with curative intent >2 years previously without evidence of relapse

- Women and partners of women of childbearing potential must agree to use adequate contraception

- Written informed consent including consent for biomarker studies

Exclusion Criteria:

- Medical or psychiatric conditions that compromise the patient's ability to give informed consent or to complete the protocol

- Prior treatment with drugs targeting EGFR such as cetuximab, panitumumab or erlotinib

- Participation in any investigational drug study within the previous 4 weeks

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