In the SWOG S9704, phase II trial (NCT00004031), T-NHL patients received initially five cycles of either cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or rituximab plus CHOP (R-CHOP). Patients who responded to the initial treatment were randomized to either three additional cycles of chemotherapy or one cycle, followed by autologous stem cell transplantation (ASCT) with carmustine or total body irradiation (TBI). The aim of this secondary analysis was to evaluate the efficacy of consolidative ASCT after first remission in this aggressive T-NHL patient population.

Study design & baseline characteristics

N = 28 T-NHL patients from the SWOG S9704

Patients who responded (even partial response) to five cycles of CHOP or R-CHOP were randomized to either consolidative ASCT (n = 15) or placebo (n = 13)

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The European Lymphoma Institute is comprised of a network of top European specialists in the field of lymphoma who are dedicated to research, training and education. Together they look to define strategies to analyse and characterize lymphoma and its common diagnostic procedures and therapeutic standards, as well as to facilitate clinical and fundamental research. This all results in the advancement of lymphoma research and it guarantees equal access for all patients to the best possible care.