Boss Baby was expected to gross somewhere in the 40-million range, maybe a skosh higher. So to have the picture to open with a $50 million take bodes well for its future, and is also a nice opening for DWA founder to leave behind. As Deadline notes:

... Most of the animated movies that Katzenberg put his fingerprints on possessed a satirical sense of humor in the Airplane-sense of the word, going back to Disney’s Aladdin and continuing well beyond Shrek. Boss Baby‘s campaign continues to carry that comedic sensibility. ...

And of course the partially-animated Beauty and the Beast continues to hold well, crossing the $400 million barrier for domestic earnings the first part of next week.