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Created for The Journal of the American Medical Association, this interactive data visualization tool shows estimated trends in HIV/AIDS death, incidence, and prevalence worldwide and by country for the years 1990 to 2013.

Avahan, a program aimed at preventing HIV in India, averted an estimated 100,178 HIV infections between 2003 and 2008, according to researchers at IHME, the Public Health Foundation of India, the Ministry of Health and Family Welfare of India, and the University of Hong Kong.

HIV/AIDS deaths dropped from a peak of more than 40,000 in 1995 to around 10,000 in 2013, and TB deaths declined at a rate of 3.7% since 2000. New TB cases are declining faster than the global average, but new HIV/AIDS cases are increasing.

New HIV infections dropped by almost one-third from the epidemic peak; TB deaths declined by 3.7% between 2000 and 2013; child deaths from malaria in sub-Saharan Africa have dropped 31.5% in the past decade. Despite major progress, the quality of programs to treat HIV varies widely.

HIV/AIDS is the leading cause of disease burden in 21 countries concentrated in four regions: Eastern and Southern Africa, Central Africa, the Caribbean, and Southeast Asia. In another seven countries, it’s the second-leading cause of disease burden. Despite widespread declines in HIV/AIDS mortality, between 2006 and 2010 HIV/AIDS deaths increased in 98 countries.

In South Africa, deaths from HIV/AIDS are often misclassified as being caused by another condition, according to a study by IHME researchers. The study found that more than 90% of HIV/AIDS deaths from 1996 to 2006 were incorrectly attributed to other causes.

Over the last 30 years, HIV/AIDS has emerged as a major global health challenge. Globally, the trend is that non-communicable diseases and injuries are accounting for a larger share of disease burden, but HIV/AIDS is a notable exception. Maintaining and expanding the response to the epidemic will require assessment of its magnitude and impact at the country level. It is also critical to examine the HIV/AIDS epidemic in the context of other health problems to clearly understand its impact and effectively allocate resources.

The Millennium Declaration in 2000 brought special global attention to HIV, tuberculosis, and malaria through the formulation of Millennium Development Goal (MDG) 6. The Global Burden of Disease 2013 study provides a consistent and comprehensive approach to disease estimation for between 1990 and 2013, and an opportunity to assess whether accelerated progress has occurred since the Millennium Declaration.

AIDS deaths are falling in most countries worldwide, but the rate of new infections increased in several countries over the past decade, threatening to undermine efforts to end the AIDS epidemic by 2030, a new scientific paper shows.

HIV prevalence over time is a critical metric for understanding the effectiveness of programs aiming to prevent HIV. Prevalence is often measured using surveillance of clinic patients, which can lead to selection bias: clinics located in areas of high HIV prevalence are often the first to be monitored by the surveillance systems, distorting the estimated HIV prevalence based on clinic data. To help understand the impact of selection bias on the estimation of HIV prevalence trends, researchers compared the efficacy of two approaches for handling selection bias.

Timely assessment of the burden of HIV/AIDS is essential for policy setting and program evaluation. In this report from the Global Burden of Disease Study 2015 (GBD 2015), we provide national estimates of levels and trends of HIV/AIDS incidence, prevalence, coverage of antiretroviral therapy (ART), and mortality for 195 countries and territories from 1980 to 2015.

An ambitious, large-scale HIV/AIDS public health program prevented an estimated 100,000 new infections over five years in the parts of India hardest hit by the AIDS epidemic, indicating that HIV prevention programs that target high-risk groups can reduce HIV rates in the broader population.

Though the rate of HIV/AIDS-related deaths in Namibia has decreased since its peak in 2005, in 2013 it remained the leading cause of death for all ages. In addition, while life expectancy in Namibia declined between 1990 and 2004 – largely due to the HIV/AIDS epidemic – it has rebounded. However, 2013 life expectancy for both sexes is slightly below 1990 levels. These findings come from a new report of Namibia health indicators.

Brazil has high burdens of tuberculosis (TB) and HIV, as previously estimated for the 26 states and the Federal District, as well as high levels of inequality in social and health indicators. We improved the geographic detail of burden estimation by modelling deaths due to TB and HIV and TB case fatality ratios for the more than 5,400 municipalities in Brazil.

In most of the world, disease burden is shifting toward non-communicable diseases and injuries and is less driven by infectious illnesses. Many countries have seen significant declines in HIV/AIDS, but success has varied across regions and countries. Although the epidemic peaked in magnitude in 2005, HIV/AIDS is still among the top 10 causes of death globally, and nearly 30 million people are living with HIV worldwide.

Spending on HIV/AIDS globally between 2000 and 2015 totaled more than half a trillion dollars, according to a new scientific study, the first long-term and comprehensive analysis of funding for the disease.