122 Conch Street is the house and residence of Squidward Tentacles. Squidward took pride in his house after winning the title of House Fancy Prince from Nicholas Whithers in a competition against his lifelong rival, Squilliam Fancyson. Squidward's house was also the location for the popular Bikini Bottom TV show Squidward's House Party. In one episode, a fish mistakes it for 122 Conch Drive. Squidward's house's mouth is a door, but originally, its mouth was closed, and a door rested underneath it. The house's exterior styling is reminiscent of an Easter Island Head.

The ground floor consists of three adjoining rooms; the one at the front being the living room. The living room consists of a bookcase with some of Squidward's jazz records, a couch, coffee table and TV. Behind the living room is the kitchen with a fridge, an island counter, and four cabinets. This is where Squidward cooks. The dining room is off to the side and consists of a round table with chairs and a clam shell chandelier. There is a room off to the side with a spiral staircase leading to the second floor. There is also an elevator. Upstairs is a bedroom on the left ear.

In here is a canopy bed, a nightstand, and a closet with alarm clocks as seen in "Employee of the Month". Off of the bedroom is a bathroom with a toilet, sink with medicine cabinet, and a Jacuzzi tub/shower. There's also a gallery where Squidward paints and plays clarinet. Other upstairs rooms include a library and back room. The Architectural Style is Polynesian.

"Skill Crane" - Squidward gives up the deed to his house while he was trying to win a prize

"Good Neighbors" - Squidward busts his head through the door screaming that "THEY'RE THE WORST NEIGHBORS EVER!!!!!!!!!!" when SpongeBob said if he was going to say something. It then comes alive and destroys Bikini Bottom.

"Rule of Dumb" - Patrick moves his house to make a ferris wheel, destroying the inside and dropping the house into the ground.

"House Fancy" - When he was in a hurry, he made SpongeBob vacuum, the vacuum cleaner exploded and the house remodeled. Also, after Patrick used Squidward's bathroom, the toilet crawled out moaning and then died.

"Giant Squidward" - The citizens of Bikini Bottom set up a trap at the house cutting off the top.

"Squid's Visit" - The house caught on fire and was vaporized while Squidward was visiting SpongeBob. It was caused by a casserole in the oven.

"That Sinking Feeling" - This time it wasn't destroyed, it just sunk underground along with the rest of Bikini Bottom.

"Growth Spout" - Mr. Krabs stole some food so he could feed his daughter Pearl. When he left, the house said "Oh well. I needed to loose a little weight anyway". What's interesting to note is that while the house just said "oh well", Squidward was angry about it and tried to call the cops, as it hints that the house isn't as grumpy as Squidward. Also in this episode the kitchen is in an unknown room in an unknown floor.

"Growth Spout" - After Mr. Krabs steals food from the house, it says "Oh well, I needed to lose a little weight anyway."

"A Friendly Game" - Same as Funny Pants, but the hands are sand and does not make an angry face. For SpongeBob's alarm at the start.

In a Nick Magazine comic, "House of Squidward", there is a switch buried in the backyard that makes Squidward's house come to life. He grows feet and arms. He is brought to rest when SpongeBob, Patrick, and Squidward cleverly disguise SpongeBob's house as a woman. Using a microphone and a speaker controlled by SpongeBob, they are able to trick the house into sitting back down in behind the walkway, and then flip the switch to keep Squidward's house from moving.