wire cons:
1. initial setup labor /time intensive.
2. need to put holes in walls and outlets.
3. not as mobile a situation have to connect by cable. (even if no laptop involved, I know my wife and as soon as I got everything wired, she would want to rearrange the room )
4. cost of wiring in some localities is aggravated by local codes. (IE in one place I lived it was you had to hire an electrician to run the wires)

All in all it comes down to preference and for me in my current situation wireless proved the best solution.