what do you mean by “auto-running”?
A link is not a program or script.
Do you mean, while editing a php script or html site you
want to see the changes in a browser synchronously?
If so you may check out html preview plugin,
but I’m not sure how well it works with php script.

If you just want to write php/html and see the result in an installed
browser you do have the possibility to launch different installed browsers
via the RUN menu.

Hi Claudia,
You first want to thank you very much for you help and you responded …

html css / php working with when npp files such as menu -> run -> Browser and/or localhost / (/file/file/file/file/file.php) option How do I get my work files and the browser opens automatically when the work …!

I’m still not 100% sure what you try to achieve.
I do understand that you are aware of the RUN menu possibilities but
I do not understand what you mean by

How do I get my work files and the browser opens automatically when the work …!

Do you mean you want to start npp, your files and the browser together?
If so, I would suggest to use the save session functionality of npp.
When you start npp with parameter -openSession <full_path_of_session_file>
the files get open as well. When putting Npp and your browser in the startup
folder of windows both programs will be started after logon automatically.

I guess I understand now. You want to edit your index.php in npp editor
and you want to start it with a browser using its url instead of its path. Correct?
So something like
GoogleChromePortable.exe http://…/index.php

If this is the case, then you cannot use RUN menu and Launch …
Instead use RUN menu RUN (F5 shortcut)