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The Buffalo defense has already seen changes in discipline under interim head coach Anthony Lynn.

"He’s done a great job of asserting himself and imprinting who he is," veteran linebacker Lorenzo Alexander said. "There have already been some immediate changes on the discipline portion of it." Lynn takes over after the Ryan brothers were dismissed and will lead the Bills against the Jets in Week 17. The Bills D/ST has failed to force a turnover in three of the last four weeks, but should have plenty of chances for takeaways in Week 17 with Ryan Fitzpatrick back under center for the Jets. Sat, Dec 31, 2016 01:25:00 PM

Buffalo will host the Cleveland Browns in Week 15, who have managed just 9.8 points per game since Week 8.

The Browns have averaged a meager 166.8 passing yards per game in that same stretch, and present a mouth-watering matchup for the Bills D/ST in a critical fantasy playoff week. The Bills D/ST is owned in 69 percent of Yahoo leagues, a number that should climb as Sunday approaches. The winless Browns have allowed an NFL-high 48 sacks in 2016 and are showing little signs of life on the offensive side of the football. As an added bonus, Buffalo has a home date with Miami and backup QB Matt Moore on tap for Week 16. Thu, Dec 15, 2016 05:11:00 PM

The Buffalo Bills will rely on rookie CB Kevon Seymour to fill-in for CB Ronald Darby (concussion) in Week 13.

"It's a big step," Seymour said. "Big responsibility, filling in for Darby and being that corner the team is relying on. I'm excited for it." It will be a downgrade for Buffalo's eighth-ranked pass defense, a group that has allowed just two 300 yard passing performances this season. The Bills D/ST will be a mid-range fantasy option on the road against the Raiders, who have allowed the fewest sacks in the NFL. Fri, Dec 2, 2016 02:55:00 PM

The Buffalo defense has allowed seven plays of 50 yards or more this season.

That total ties the Bills with the Oakland Raiders for most 50 yard plays allowed in 2016. The Bills currently sit 13th among NFL defenses in pass defense, but big plays have done damage to this group. Buffalo will need to look for a solution to the big play troubles during their bye, as they will return to face A.J. Green, Allen Robinson, Amari Cooper, and Antonio Brown in consecutive weeks. Fri, Nov 11, 2016 04:27:00 PM

Bills coach Sean McDermott said the team is "hopeful" Jordan Matthews (chest) will return "sooner than later."

Matthews is dealing with a chip fracture in his sternum which will sideline him at least through this week and likely more. It sounds like the Bills expect him back for Week 1, but the missed time is a big concern as he attempts to settle in with his new team. With uncertainty surrounding Matthews, Zay Jones looks like a good flier in the 12th round.

Bills WR Rod Streater was carted off with a left leg injury in Buffalo's second preseason game.

While catching a pass in the fourth quarter Streater twisted his leg and was unable to make it off the field under his own power. He had two catches for 40 yards until that point. Streater was drawing rave reviews early in camp.

Bills LT Cordy Glenn received an injection in his troublesome foot this week.

Glenn has been struggling with the foot for months, but the Bills hope the injection will "knock out" the soreness. Glenn is labeled week to week, with coach Sean McDermott saying he is "hopeful" the left tackle will be ready for Week 1. With Seantrel Henderson suspended, the Bills will be in real trouble if Glenn is forced to miss games, which seems like a real possibility at this point.

It's the former starter's second substance-abuse suspension of the season. Henderson said he smokes marijuana for pain relief from his Crohn's disease. Cyrus Kouandjio will finish out the year as Buffalo's swing tackle. Henderson is signed for $690,000 next season. Any time a player earns a 10-game substance-abuse ban, their career is in doubt. 24-year-old Henderson will not be eligible to return until Week 6 of next season.