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The Trustpower TECT Rescue Helicopter flew a 58-year-old Rotorua woman to Waikato Hospital with pelvic, chest and abdominal injuries and her husband was flown by the Taupo-based Greenlea Rescue Helicopter to Waikato Hospital.

The remaining victims were taken to Rotorua Hospital by St John Ambulance.

Senior Sergeant Mike Membery of the Bay of Plenty Police District Command Centre told the Rotorua Daily Post there were multiple patients.

"There are at least six patients. This is a hard one to explain as they were all wearing their seatbelts and the weather was good."

He said the investigation into the cause was ongoing and he couldn't say what it could have been, but he wanted to give the public a general warning on driving to the conditions.