Notes

Acknowledgment

The authors gratefully acknowledge the collaboration of the Munich Study Centre, Munich, Germany, and would like to thank Sandra Cuscó, PhD, from Complete Medical Communications, who provided medical writing support funded by AstraZeneca. Final approval of the manuscript lay solely with the authors. The NEWEST study was funded by AstraZeneca.

Conflict of interests

Irene Kuter, Jose Bines and Nadia Harbeck have acted as consultants to or in advisory roles to AstraZeneca. Julia Gee and Robert Nicholson have received research funding from AstraZeneca. Elizabeth Lowe and Ugochi Emeribe are employees of AstraZeneca and hold stock ownership with AstraZeneca. Elizabeth Anderson and Francisco Sapunar are former employees of AstraZeneca. Elizabeth Anderson holds stock ownership with AstraZeneca. Roberto Hegg, Christian Singer and Rajendra Badwe have no conflicts of interest to disclose.