Cost Effectiveness Modeling for HTA

Presentation

The course will introduce the concepts of health technology assessment (HTA) and economic evaluations in health covering the history of their development and rationale for their use. The use of HTA for policymaking and reimbursement will be covered and we will discuss alternative frameworks for economic evaluation. A focus will be placed on cost-utility analyses and cover both trial-based and model-based analyses, including decision tree and Markov models. The outputs of economic evaluations will be discussed and we will cover the importance of uncertainty and how to assess this in sensitivity analyses. There will be hands-on exercises through-out the course to enable students to try out modeling in Excel and to generate results. Finally, the course will also cover emerging fields in HTA such as the use of real-world evidence and key debates such as: should we include spillover effects in economic evaluations? how much should we be willing to pay for health gain (and how should we determine this)?

Objectives

Understand the concepts and rationale of HTA and types of economic evaluation

Understand when you would use a decision tree model and how they work

Understand when you would use a Markov model, how they work and how to use them to inform decision making

Appreciate the importance of uncertainty in economic evaluations and how this can be assessed

Be able to generate a probabilistic Markov model in Excel and produce and interpret outputs

Understand the concept of value of information and calculate this from probabilistic model results

Learn about key developments and debates in HTA including precision medicine, real-world evidence and the willingness to pay threshold

For more information on the course, please refer to this document, and to this document for information on the schedule.