So way back in the day when I used to watch late night WGN, there was a movie about this fairly old couple who acquired a painting of a girl and a farmhouse. The creepiness was that every morning or so, the picture would change in kind of a "slice of life" fashion where the girl in the painting would be in different places doing different s**t. Eventually, the scenes change to be even creepier when she starts making panic-y gestures and disappears/reappears randomly. Noone knows what the hell this movie/show was, and I've been looking for it for years. I'm pretty sure it was a movie, but I could be wrong.

Sounds like a modification of "The Cemetery" episode of Night Gallery.

Synopsis from TV.com:

"Once the nephew is alone in the house, he notices the painting at the bottom of the stairs showing the house and cemetery, has changed. There is now a mound showing the grave of the old man. Next, the coffin is raised, then the coffin is open, the old man is shown leaving the coffin, then approaching the house. Each time a new scene is shown in the painting, it makes the nephew more frightened; he tries to call the manservant he then calls the police but each time he is cut off before being put through. Eventually he is driven so mad that he falls down the stairs, he is dead before he lands at the bottom!"