If abnormal
bleeding persists or is severe, appropriate investigation should be
instituted to rule out the possibility of organic pathology, and appropriate
treatment should be instituted when necessary.

As women
continue using Depo-Provera CI, fewer experience irregular bleeding
and more experience amenorrhea. By month 12 amenorrhea was reported
by 55% of women, and by month 24 amenorrhea was reported by 68% of
women using Depo-Provera .

The effect
of using a depo provera injection does not cease immediately after
you stop taking the contraceptive.