About this book

This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. The Neural Crest is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.

"Any developmental biologist will enjoy this book [...] the questions and the experimental approaches will be appreciated by all."- BioEssays

Contents

Foreword Lewis WolpertPreface N. Le Douarin

1. Methods for identifying neural crest cells and their derivatives2. The migration of neural crest cells3. The neural crest: a source of mesenchymal cells4. From the neural crest to the ganglia of the peripheral nervous system: the sensory ganglia5. The autonomic nervous system and the endocrine cells of neural crest origin6. The neural crest: source of pigment cells7. Cell lineage segregation during neural crest ontogeny

Concluding remarks and perspectivesIndex

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