Workers exposed to higher amounts of endotoxin and (1→3)-ß-D-glucan, had an increased risk for respiratory symptoms as compared to those with lower exposure. Stomach problems and nausea were associated to higher (1→3)-ß-D-glucan exposure. MRF 4 had a higher (1→3)-ß-D-glucan exposure compared to 7 and 9, and respiratory symptoms, unusual tiredness and vomiting were reported more often in MRF 4. Monocyte numbers and ESR were significantly decreased in MRF 4 compared to MRF 7 and 9.

Conclusion

The results suggest that MRF workers exposed to higher levels of endotoxin and (1→3)-ß-D-glucan exhibit various work-related symptoms. The decrease in ESR and monocyte numbers related to (1→3)-ß-D-glucan exposure can indicate that this agent has a blocking effect on the inflammatory response in blood.