WASHINGTON — Some of the most iconic artifacts of aviation and space history will be getting an updated display for the 21st century, with the Apollo moon landing as the centerpiece.

For the first time since its 1976 opening, the Smithsonian’s National Air and Space Museum plans to overhaul its central exhibition showing the milestones of flight. The extensive renovation announced today will be carried out over the next two years with portions of the exhibit closing temporarily over time, said Museum Director J.R. “Jack” Dailey.

Charles Lindbergh’s “Spirit of St. Louis” aircraft from the first trans-Atlantic flight, John Glenn’s Mercury capsule from his first Earth orbit and an Apollo Lunar Module recalling America’s first moon landing will be among the key pieces to be featured. Such artifacts have made the Air and Space Museum the nation’s most-visited museum, drawing 7 million to 8 million visitors each year.

The project will be funded by the largest corporate donation in the Smithsonian’s history. Today, Boeing announced a $30 million gift to the museum for its exhibits and education programs. The central gallery will be renamed the Boeing Milestones of Flight Hall. In all, Boeing has donated nearly $60 million to the museum throughout its history, the company said.

The exhibition overhaul also marks the start of a renovation of the entire building through 2020, which will require federal funding. Plans call for adding an observatory on the roof.

Visitors walk through the Milestones of Flight Gallery, the main hall of the Smithsonian’s National Air and Space Museum, in Washington.

Curators plan to reimagine the museum’s largest exhibit with more stories, context and digital interaction.

“This is all part of us moving into the future,” Dailey said. “Times have changed, and there are opportunities for producing exhibitions that weren’t even imagined 38 years ago.”

The current “Milestones of Flight” gallery includes a somewhat random mix of technical marvels, including Mercury, Gemini and Apollo capsules spread out across the floor, the first plane to break the sound barrier and other aircraft hanging above. The exhibit descriptions have not been notably updated since President Gerald Ford opened the museum in 1976, said chief curator Peter Jakab.

Plans for the renovation call for moving the large Lunar Module, a test flight vehicle, into the central exhibit for the first time and showing a progression from earlier space capsules during the space race.

The popular Apollo 11 command module Columbia that brought humans back to Earth from the moon will be moved out of the gallery. It will eventually become the centerpiece of a new Apollo gallery elsewhere in the museum.

The new design will “deepen the experience” with more description and richer stories and connections between the artifacts on display, Jakab said.

Apollo Lunar Module number 2, is currently on display in the Lunar Exploration Vehicles gallery in the National Air and Space Museum in Washington.

Beyond the museum’s focus on science and technology, it will add more stories about the people, politics and business behind aviation and space achievements, said curator Robert van der Linden. Curators have even redefined what qualifies as a milestone of flight, saying it’s not just a first but must illustrate widespread impact.

For the first time, the museum will add science fiction to the “Milestones of Flight” exhibit with a model of starship Enterprise from “Star Trek.” In the 1970s, a “Star Trek” actress made TV ads to help NASA recruit a diverse corps of new astronauts, connecting fiction with reality in the space age.

A new media wall, digital screens and content for mobile devices will add more layers to the visitor experience, Dailey said.

“We’re trying to figure out what the museum needs to do to stay in touch,” Dailey said. “We want to inspire people of all ages to want to know more and to do more.”