Genes mapping within a 1Mb window of associated SNPs (Table 2) were tested for interaction with genes from other loci. Interactions with Pearson correlation >0.5 shown (P<10−100). Only the genes known to contain causal mutations (HLA-DQA1, HLA-DQB1) were analysed from the HLA region, “HLA-DQB2 / HLA-DQB1” is a single expression probeset mapping to both genes. No probe for THEMIS was present on the earlier version of the U133 array, however in a subset analysis of U133 Plus2.0 data, THEMIS is co-expressed in the major immune gene cluster