Katie joined Jason Sudeikis to present a video called "Red Hook Rising," bringing attention to those affected in Brooklyn. Kristen, meanwhile, praised New Jerseyans and introduced Jon Bon Jovi. Blake spoke about Connecticut and brought out Chris Martin, who performed with Michael Stipe. Bruce Springsteen, Alicia Keys, Kanye West, and many more musicians performed at the 12/12/12 concert. Paul McCartney gave a sensational performance when he joined up with the surviving members of Nirvana, Dave Grohl and Krist Novoselic, to perform a new song called "Cut Me Some Slack."

The concert was broadcast both on TV and for free in movie theaters in the tri-state area, so Sandy victims had a place to enjoy the music. Superstorm Sandy left many in New York and New Jersey homeless and without power after it drove through the area in late October.