Many artists such as Titian have depicted this story by showing Andromeda, her rescuer Perseus, and the sea monster all in the same composition. In this work, Rembrandt shies away from classical conventions by showing her not as a glamorous beauty but as a frightened naturalistic looking girl. No other figure is included, but her alarmed look out of the picture space to the right creates narrative tension. The painting is an example of Rembrandt's rejection of idealized beauty. Since he did not believe true beauty existed naturally, he painted women as he saw them; naturally imperfect and flawed.[2]

Rembrandt's subsequent nude mythological paintings from this period Diana Bathing and Danaë show his evolving portrayal of the nude.