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Transcription Factor 4 ELISA Kits (TCF4)

On www.antibodies-online.com are 9 Transcription Factor 4 (TCF4) ELISA Kits from 5 different suppliers available. Additionally we are shipping TCF4 Antibodies (82) and TCF4 Proteins (9) and many more products for this protein. A total of 106 TCF4 products are currently listed.

In the sex-combined analyses, we identified one novel locus (TCF7L2/HABP2) for WHRadjBMI and eight previously established loci at P < 5x10-8: seven for BMI, and one for WHRadjBMI in African ancestry individuals. An additional novel locus (SPRYD7/DLEU2) was identified for WHRadjBMI when combined with European GWAS.

In renal transplant patients, TCF7L2 (show TCF7L2 ELISA Kits) rs7903146 is strongly and independently associated with posttransplant diabetes mellitus and might hold the potential to identify patients at risk for this complication.

Mouse (Murine) Transcription Factor 4 (TCF4) interaction partners

TCF-4 as a co-activator of p65 (show NFkBP65 ELISA Kits) in the potentiation of proinflammatory cytokine production in macrophages and aggravation of high-fat diet induced chronic inflammation and insulin (show INS ELISA Kits) resistance in mice.

TCF4 Antigen Profile

Antigen Summary

This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.