Australia's biggest drug company CSL is trying to dampen the effect of criticisms made by the US Food and Drug Administration (FDA) of its manufacturing operations. The details of the FDA's criticisms have been obtained by News Limited newspapers under a Freedom of Information request, based on two years' worth of audit reports. Among the FDA's criticisms are concerns about a "multitude of manufacturing flaws" and "objectionable conditions and practices" used to make vaccines. CSL insists its vaccines are safe and it says it is fixing all of the identified problems.