Researchers have demonstrated that an alpha-hemolysin nanopore can identify epigenetic modifications of DNA, suggesting that eventually, nanopores will be able to perform single-molecule methylation sequencing of a DNA strand — an advance over current methylation sequencing methods, such as bisulfite sequencing, which require the DNA to be modified or amplified.

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This webinar will discuss the benefits of a rapid targeted next-generation sequencing (TNGS) panel, using dried blood spots, for second-tier newborn metabolic and hearing loss screening and its immediate utility for high-risk diagnostic testing in the neonatal intensive care unit.