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Microsomal Triglyceride Transfer Protein Proteins (MTTP)

On www.antibodies-online.com are 5 Microsomal Triglyceride Transfer Protein (MTTP) Proteins from 3 different suppliers available. Additionally we are shipping MTTP Antibodies (47) and MTTP Kits (33) and many more products for this protein. A total of 91 MTTP products are currently listed.

In chronic hepatitis C patients infected with HCV genotype 3 and with the TT/GT genotype of the MTTP -493G/T SNP, a significant increase in hepatic steatosis was observed, which may indicate that this SNP has a significant influence on the accumulation of triglycerides in hepatocytes.

High expression of MTTP is associated with high carotid intima-media thickness.

Findings from meta-analysis indicate that the MTP (show MT1B Proteins) -493G/T polymorphism may contribute to the development of non-alcoholic fatty liver disease. Thus, the MTP (show MT1B Proteins) -493G/T polymorphism may be a biomarker for the early detection of the disease.

Microsomal triglyceride transfer protein protein plays a critical role in lipid droplet maturation, but does not regulate total body fat accumulation.

data provide the first in vivo evidence of the transcriptional regulatory activity of beta-apocarotenoids and identify microsomal triglyceride transfer protein and its transcription factors as the targets of their action. This study demonstrates that beta-carotene induces a feed-forward mechanism in the placenta to enhance the assimilation of beta-carotene for proper embryogenesis.

intestine-specific Mttp deletion is beneficial in young septic mice but harmful in aged mice

identified microsomal triglyceride transfer protein, which we show is also under the transcriptional regulation of C/EBPbeta (show CEBPB Proteins) and -delta, as a novel player in the presentation of endogenous lipid antigens by adipocytes

measurements of the transfer of phospholipids (PLs (show CTSC Proteins)) and cholesteryl esters (CEs)to acceptor vesicles by purified MTP showed TAG transfer activity was the most robust, and CE and PL transfer activities were 60-71% and 5-13% of the TAG transfer activity

In a genetic study of lipid transport and metabolism, larval levels of microsomal triglyceride transfer protein (Mtp), the protein responsible for packaging triacylglycerol and beta-lipoproteins into lipoprotein particles, are unchanged by feeding.

MTTP Protein Profile

Protein Summary

MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.