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San Francisco's Mayor Ed Lee is obsessed with his city's burgeoning startup scene.

In fact, he visits a startup every Tuesday, he said in an on-stage interview at the TechCrunch Disrupt conference.

It might seem obvious to think of San Francisco as a congenial place for new tech companies. But a decade ago, San Francisco seemed consigned to being a bedroom community for Silicon Valley's office parks. Since then, Salesforce.com exploded and Twitter, and Zynga got started.