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The kit provides researchers with a cost-effective product for enzymatic removal of unincorporated primers and nucleotides from PCR and sequencing reactions, with no degradation of target PCR products, GE said. The kit contains two enzymes designed to work together, with one tube of exonuclease 1 at a concentration of 10 enzyme units per µL; and one tube of Illustra alkaline phosphatase at a concentration of one enzyme unit per µL.

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This webinar will discuss an optimized protocol for methyl-CpG binding domain sequencing (MBD-seq), which enables comprehensive, adequately powered, and cost-effective large-scale methylome-wide association studies (MWAS) of almost all 28 million CpG sites in the genome.