Anti-NS3 T cell receptor (I2B11), pCDTCR1(TCR-L354)

The vector of anti-NS3 T cell receptor (TCR) is constructed for the engineering of T cell to target HCV NS3. The T cells are genetically modified through transduction with a lentiviral vector expressing NS3-specific T cell receptor. And the vector product was designed for the treatment of HCV infection.

Details

Target

NS3

Target Species

HCV

Epitope

aa 1073-1081

Format

Non-modified

HLA

HLA-A2

Targeting Diseases

HCV infection

Vector Name

pCDTCR1

Vector Length

~8kb

Vector Type

Lentiviral

Antibody Clone

I2B11

Antibody Host

Human

Target

Gene Name

Nonstructural protein 3

Official Symbol

NS3

Synonyms

Nonstructural protein 3; NS3; p-70

Introduction

Nonstructural protein 3 (NS3), also known as p-70, is a viral nonstructural protein that is 70 kDa cleavage product of the hepatitis C virus polyprotein. It acts as a serine protease.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.