The Blue Jays had five two-strike hits off Hamels, four of them in a five-run third, and Marco Estrada took a shutout into the ninth inning to lead Toronto to a 10-1 romp in the opener of their AL Division Series rematch Thursday.

“When you give up the amount of runs that I did early in the game, it can kind of deflate anything and everything of what home-field advantage really is,” Hamels said. “It was a major letdown for what I was able to not do.”

The long three-run homer Jose Bautista hit off reliever Jake Diekman in the ninth inning, before gently tossing his bat to the ground, didn’t really have much an impact on this game. Not like Bautista’s emphatic bat flip after his tie-breaking homer in the ALDS Game 5 clincher last October.

Estrada gave up four hits and no walks and struck out six for the wild-card Blue Jays. The All-Star right-hander won Game 3 in last year’s ALDS after Toronto lost the first two at home.

When Josh Donaldson hit a hard liner toward four-time Gold Glove third baseman Adrian Beltre with two outs in the third, it appeared Hamels would get out of that inning without giving up a run. Instead, the liner ricocheted off Beltre’s glove and into left field for an RBI double.

Then Edwin Encarnacion hit a soft tailing liner on a two-strike pitch, and the ball went off Hamels’ outstretched glove for an infield single. Bautista followed with an RBI single on two-strike pitch before Russell Martin walked to load the bases and Troy Tulowitzki followed with a three-run triple.

Toronto fan charged: The man who threw a beer can at Baltimore’s Hyun Soo Kim as the outfielder caught a flyball during the AL wild-card game has been charged with mischief.

Ken Pagan, 41, a copy editor for Postmedia, reported to a police precinct Thursday evening. He later was released and is due in court in late November.