JAMA 272,2: 166-167, July 13, 1994. Recently, a Seattle company had to pay $21 million and surrender its patents after a group of Harvard researchers alleged that company scientists assigned by Nature to review their unpublished article had stolen their data ("Suit Alleges Misuse of Peer Review." Science 270:1912, December 22, 1995).

For more than a decade, Spiegelman and his postdocs, including Jeff Schlom, Richard Axel and Don Kufe, all of whom went on to distinguished careers of their own at Columbia, NCI and Harvard, pursued the elusive breast cancer virus. Spiegelman's last paper on that topic, "Properties of retrovirus-like particles produced by a human breast carcinoma cell line: immunological relationship with mouse mammary tumor virus proteins" (Proc Natl Acad Sci U S A. 1984 Jul;81(13):4188-92), appeared in 1984, a year after his death. No breast cancer virus has ever been found.

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Doubtless unbeknownst to the Maharaj Ji, J. Michael Bishop and Harold Varmus at the University of California in San Francisco already were in the process of establishing that many cancers were the product of mutations in normal genes—i.e., life itself--which then triggered the wild proliferation of previously healthy cells--i.e., cancer--or else failed in their mission to suppress such proliferations.

Crewdson, J. "The Great AIDS Quest." Chicago Tribune; November 19, 1989. Poiesz, B.J., et al. "T-cell lines established from human T-lymphocytic neoplasias by direct response to T-cell growth factor." PNAS 77:11,6815-6819, November 1980. In addition to HUT-102, Poiesz established his own continuous culture of Charlie Robinson's cells, which he called CTCL-3.

Bishop, J. M. "The molecular biology of RNA tumor viruses: A physician's guide." N. Engl. J. Med. , 303:12, 675. September 18, 1980. The lecture on which the article was based was first delivered by Bishop in 1979.

Miyoshi, I., et al. "A T-cell line derived from normal human cord leukocytes by co-culturing with human leukemic T-Cells." GANN 72:978 - 981, December 1981. Received May 28, 1981. The paper reports that the MT-2 cell line was established via co-culture two months after creation of the primary patient culture in November 1979, which would date MT-2 from January 1980.

Yoshida, M., et al. "Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease." PNAS 79:2031, March 1982. Communicated November 23, 1981.

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J. Mason to P. Gill, July 25, 1985.

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Gallo, R. Virus Hunting. New York: Basic Books, 1991.

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Popovic, M., et al. "The virus of Japanese adult T-cell leukaemia is a member of the human T-cell leukaemia virus group." Nature 300:63, November 4, 1982.

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Kalyanaraman, V. S., et al. "Immunological properties of a type C retrovirus isolated from cultured human T-lymphoma cells and comparison to other mammalian retroviruses." J. of Virology, 906-915, June 1981. The article states that HTLV-related sequences from the fresh T-cells of two leukemia patients, a child and a woman, would appear in "Poiesz et al., submitted for publication."

Gallo, R. C., and Wong-Staal, F. "Retroviruses as etiologic agents of some animal and human leukemias and lymphomas and as tools for elucidating the molecular mechanism of leukemogenesis." Blood 60:3, 545 - 557, September 1982.