Reference genomes of Clostridium difficile

Reference genomes of Clostridium difficile

Reference genomes of Clostridium difficile

Overview

We have sequenced and annotated 15 high quality reference genomes of Clostridium difficile. These genomes belongs to different ribotypes of C. difficile including hypervirulents ribotypes (RT027 and RT078).

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Data Use

This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale. See our data sharing policy.

Related Tools and Data

A free genome browser and annotation tool that allows visualisation of sequence features, next generation data and the results of analyses within the context of the sequence, and also its six-frame translation.

A Java application for displaying pairwise comparisons between two or more DNA sequences. It can be used to identify and analyse regions of similarity and difference between genomes and to explore conservation of synteny, in the context of the entire sequences and their annotation.

Related Groups

The host-microbiota Interactions laboratory studies the mechanisms that underlie how micro-organisms in the gut, nasopharynx and uro-gential tract interact with their host during periods of health and disease. In particular the team seek to develop novel ways to treat diseases that are associated with unwanted imbalances in the micro-organism population.