Emirates has confirmed that all 300 passengers and crew members aboard the flight are safe.

Even though this marks the fifth Boeing 777 to be written off in five years, the model remains one of the safest airplanes to ever fly.

In the 21 years since the plane entered service, only six Boeing 777s have been written off, because of fire, crashes, or disappearances, with Wednesday's Emirates flight being the sixth.

A mere 0.4% of the 1,412 777s ever produced have been involved in crashes or incidents that left the plane damaged beyond repair. Compare that with the 4% of the 1,522 747s that have been written off over the years; the 747 itself is considered an incredibly reliable and safe aircraft.

The first 777 incident took place in 2008, when a British Airways jet suffered engine failure on landing and crashed on the runway at Heathrow Airport. The aircraft — operating as BA Flight 38 — experienced a sudden loss of power, and the cause of the incident was eventually traced back to a design fault in Rolls-Royce's Trent turbofan engines that allowed ice to build up in the fuel lines. Though nearly 50 people were injured, no one died in the crash.

British Airways Flight 38 on the runway at London Heathrow. REUTERS/Stephen Hird The second incident took place in 2011, when an EgyptAir 777 caught fire while parked at a gate at Cairo Airport. All passengers were able to deplane, and only a few people were injured. Egyptian investigators believe the fire was caused by a short circuit and was fed by the pilot's onboard oxygen supply.

The third hull loss and first fatal accident involving a 777 occurred in 2013, when Asiana Flight 214 crashed while landing in San Francisco. Three of the 291 passengers were killed, while all 16 crew members survived. Investigators at the NTSB attributed the crash to pilot error.

The fourth incident took place on March 8, 2014, when a Malaysia Airlines 777-200ER operating as Flight MH370 disappeared while flying from Kuala Lumpur, Malaysia, to Beijing. The 600,000-pound plane — registration number 9M-MRO — vanished with 239 passengers and crew aboard. So far, only pieces of the plane have been located.

Asiana Flight 214 after it crashed at the San Francisco International Airport in July 2013. AP Photo/Marcio Jose Sanchez Of those incidents, only the EgyptAir one can be attributed to a failure with the plane, though that could change if investigators are able to locate the wreckage of MH370 and if an investigation of the Emirates crash finds the plane to be at fault.

Since entering service in 1995, the 777 has become a workhorse for long-haul international airlines. Along with the Airbus A330, the 777 helped revolutionize modern air travel — eventually rendering the jumbo jet obsolete.

Boeing developed the 777 from scratch in the early 1990s with a 10,000-person team at an estimated cost of $5 billion. It was the seventh all-new jetliner introduced by the airplane maker.

The Boeing 777-200 at its world debut in 1994. REUTERS/Jeff Vinnick The 777 was conceived to fill a hole in the market at the time that called for a large wide-body long-haul airliner, smaller than the company's legendary 747 jumbo but bigger than the 767, a "mini-jumbo."

In the process, the 777 and its Airbus counterparts became the perfect fuel-efficient, long-distance aircraft. As a result, four-engine airliners such as Boeing's 747 jumbo and Airbus' A340 have been relegated to near-relic status.

Emirates is the largest operator of the 777, with a fleet of 156 of the Boeing jets. The Dubai, United Arab Emirates-based airline flies 11% of all 777s ever produced. The aircraft involved in Wednesday's crash, A6-EMW, was delivered to Emirates on March, 28, 2003, and was the 434th triple-seven to roll out of Boeing's Everett, Washington, factory.