Top 22 Marketing Strategies for Management that will Boost your Bottom Line.

Learn the Top Marketing strategies to implement in your business to increase your bottom line. Learn different tools to increase revenue and credibility by offering new approaches. Get new, easy and effective marketing idease from Manon Pilon, author of 2 books on the subject. Learn how to double your revenue and build customer loyalty. Learn the marketing strategies that have transformed medical-spas, spas and clinics around the world directly from the speaker herself who has helped transform such businesses all over the world.

ANTI-AGEING EFFECT OF PURE SILK TISSUE WITH ULTRA-FINE SILVER NANO-COATING CORRELATION BETWEEN CLINICAL AND BIOLOGICAL RESULTS ESTABLISHED WITH A SURVIVING HUMAN SKIN MODEL.

Objectives of the studies

The anti-ageing effect of pure silk (100%) tissue with ultra-fine silver (999.9) nano-coating (Mrs KUDRINA as inventor) was evaluated on healthy volunteers and with

a biological evaluation on an experimentally aged human skin model.

Methods

The first clinical study on 20 volunteers allowed to evaluate the anti-ageing efficacy of an eye mask after 1 night application on bags under eyes, crow's foot wrinkles, dark eye-rims and hydration.

The second study on 13 volunteers was conducted after 1 month application of a helmet mask to evaluate skin glow and skin density.

For the biological evaluation, silk tissue nano-coated with silver was applied on skin fragments experimentally aged by UV (A and B) and maintained in survival during 14 days.

Results

The first clinical study has shown the efficacy of 1 night application of the eye mask, with a significant decrease (23.5%) of bags under eyes (dermatological scoring), of crow's foot wrinkles by 6.6 % (profilometric evaluation by image analysis), of dark eye-rims by 3.2 % (chromometric evaluation) associated with a significant increase of hydration around eyes by 4.1% (corneometric measurement).

The second clinical study, after 1 month of daily use of the helmet mask, has revealed a significant increase of skin glow by 49% (dermatological scoring) and of skin density by 8.5 % (echographic measurement).

The application of silk tissue nano-coated with silver on human skin fragments maintained in survival allowed to obtain a significant increase by 60% of epidermis renewal (mitotic index increased) and of glycosaminoglycans rate (histologic analysis) associated with a significant decrease of free radicals by 13% (H2O2 assay).

Conclusion

In our dermatological experience, it is the first time we obtained a complete correlation between clinical and biological anti-aging effect of a cosmetic product:

„Photobiomodulation“ respectively „Low-Level Light Therapy (LLLT)” is the application of light of different wavelengths, power and energy densities in various fields of medicine, e.g. for tissue regeneration and scarring, blood perfusion and pain therapy.

In this lecture, we provide a brief survey of the current state of research in the field of photobiomodulation in plastic, aesthetic and reconstructive surgery and we present preliminary results from the first controlled laboratory trial on the effect of pulsating cold red light on angiogenesis at the chick chorioallantoic membrane (CAM), which is a well-known bioreactor.

As light source a Repuls7 (medical product class 2b by Repuls Lichtmedizintechnik GmbH, Vienna), consisting of 7 LEDs (Light Emitting Diodes), emitting pulsating incoherent red light at a wavelength range from 600-660nm was applied. Photos from the blood vessels trough a reflected-light microscope were taken once every day and analysed for the junctions of the blood vessels. In the CAM assays treated with LLLT the number of junctions was higher compared to the CAM assays in the control group.

Our results reveal that the effect of photobiomodulation at 600-660nm wavelength on angiogenesis can be verified in comparison to a control group on the CAM model. Angiogenesis is an important factor regarding wound healing and tissue regeneration. Due to the specific properties of the chicken CAM model, the information value from the clinical point of view is higher than in “conventional” pure in-vitro experiments.

Platelet-Rich Plasma (PRP) has emerged as a new treatment modality in regenerative plastic surgery, and preliminary evidence suggesting that it might have a beneficial role in hair re-growth. Here we reported the results of a randomized, trichoscan evaluator blinded, placebo half-head group study to compare the hair re-growth with PRP versus placebo. To investigate the safety and clinical efficacy of autologous PRP injections for pattern hair loss.

PRP, prepared from a small volume of blood, was injected on half of the selected patients’ scalps with pattern hair loss. The other half was treated with placebo. Three treatments were given for each patient, with intervals of 30 days.The endpoints were hair re-growth, hair dystrophy as measured by dermoscopy, burning or itching sensation, and cell proliferation as measured by Ki-67 evaluation. Patients were followed for 2 year.

23 patients were enrolled, three of whom were excluded. At the end of the 3 cycles of treatment, the patients presented clinical improvement in the mean number of hairs, with a mean increase of 33,6 hairs in the target area, and a mean increase in total hair density of 45,9 (number of hairs/cm2) compared with baseline values. No side-effects were noted during treatment. Microscopic evaluation showed the increase of epidermis thickness and of the number of hair follicles two weeks after the last PRP treatment compared to baseline value (p<0.05). We also observed previously an increase of Ki67+ keratinocytes of epidermis and of hair follicular bulge cells, and a slight increase of small blood vessels around hair follicles in the treated skin compared to baseline (p<0.05). Our data clearly highlights the positive effects of PRP injections on male pattern hair loss without major side-effects. PRP may serve as a safe and effective treatment option against hair loss, and calls for more extensive controlled studies.