Pharmaceutics is one of the most diverse subject areas in all of pharmaceutical science. In brief, it is concerned with the scientific and technological aspects of the design and manufacture of dosage forms or medicines. An understanding of pharmaceutics is therefore vital for all pharmacists and those pharmaceutical scientists who are involved with converting a drug or a potential drug into a medicine that can be delivered safely, effectively and conveniently to the patient.

Now in its fourth edition, this best-selling textbook in pharmaceutics has been brought completely up to date to reflect the rapid advances in delivery methodologies by eye and injection, advances in drug formulations and delivery methods for special groups (such as children and the elderly), nanomedicine, and pharmacognosy. At the same time the editors have striven to maintain the accessibility of the text for students of pharmacy, preserving the balance between being a suitably pitched introductory text and a clear reflection of the state of the art.

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Published:June 2013

Imprint:Churchill Livingstone

ISBN:978-0-7020-4291-1

Contents

What is âpharmaceuticsâ?â0

1. Design of dosage forms

â0

Peter York

PART 1: Scientific principles of dosage form design

â

2. Dissolution and solubilityâ00

Michael E. Aulton

3. Properties of solutionsâ00

Michael E. Aulton

4. Surfaces and interfaces 00

Graham Buckton

5. Disperse systemsâ00

David Attwood

6. Rheology

Christopher Marriot

7. Kineticsâ00

W. John Pugh

PART 2: Particle science and powder technology

â00

8. Solid-state propertiesâ00

Graham Buckton

9. Particle size analysisâ00

J.N. Staniforth, Kevin M.G. Taylor

10. Particle size reduction and size separationâ00

Michael E. Aulton, J.N. Staniforth

11. Mixingâ00

Andrew M. Twitchell

12. Powder flowâ00

Michael E. Aulton

PART 3: Pharmaceutical microbiology and sterilization

â00

13. Fundamentals of microbiologyâ00

Geoffrey W. Hanlon

14. Pharmaceutical applications of microbiological techniquesâ00

Norman A. Hodges

15. Action of physical and chemical agents on microorganismsâ00

Geoffrey W. Hanlon, Norman A. Hodges

16. Principles of sterilizationâ00

Susannah E. Walsh, Jean-Yves Maillard

17. Sterilization in practiceâ00

Jean-Yves. Maillard, Susannah E. Walsh

PART 4: Biopharmaceutical principles of drug delivery

â000

18. Introduction to biopharmaceutics 000

Marianne Ashford

19. Gastrointestinal tract - physiology and drug absorptionâ000

Marianne Ashford

20. Bioavailability - physicochemical and dosage form factorsâ000

Marianne Ashford

21. Assessment of biopharmaceutical propertiesâ000

Marianne Ashford

22. Dosage regimensâ000

John H. Collett, Soraya Dhillon

PART 5: Dosage form design and manufacture

â000

23. Pharmaceutical preformulationâ000

Simon Gaisford

24. Solutionsâ000

Sudaxshina Murdan

25. Clarificationâ000

Andrew M. Twitchell

26. Suspensions 000

Susan A. Barker

27. Emulsions and Creams 000

Gillian M.Eccleston

28.Powders, granules and granulation 000

Michael E. Aulton, Malcolm P. Summers`

29. Dryingâ000

Michael E. Aulton

30. Tablets and compactionâ000

GÃ¶ran Alderborn

31. Modified-release oral drug delivery 000

Abdul W. Basit, Emma L. McConnell

32. Coating of tablets and multiparticulatesâ000

Stuart C. Porter

33. Hard capsulesâ000

Brian E. Jones

34. Soft capsulesâ000

Keith G. Hutchison, Josephine Ferdinando

35 Dissolution testing of solid dosage forms

Abdul W. Basit, Ana Cristina Freire

36 Parenteral drug delivery

Robert Lowe

37. Pulmonary drug deliveryâ000

Kevin M. G. Taylor

38. Nasal drug deliveryâ000

Gary P. Martin, Alison B. Lansley

39. Topical and transdermal drug delivery 000

Adrian C. Williams

40. Wound dressingsâ000

Gillian M. Eccleston

41. Ocular drug delivery 000

Hala Fadda, Ashkan Khalili, Peng T. Khaw, Steve Brocchini

42. Rectal and vaginal drug deliveryâ000

Joseph J. Tukker, Sanjay Garg

43. Design and administration of medicines for children and the elderly 000