Ibuprofen/famotidine (By mouth)

Famotidine (fam-OH-ti-deen), Ibuprofen (eye-bue-PROE-fen)

Treats pain and arthritis. This medicine contains an NSAID and a medicine to protect your stomach from damage caused by the NSAID.

Duexis

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to ibuprofen, aspirin, famotidine, or similar medicines. Do not use right before or right after a heart surgery, called coronary artery bypass graft (CABG).

How to Use This Medicine:

Tablet

Your doctor will tell you how much medicine to use. Do not use more than directed.

Swallow the tablet whole. Do not break, crush, divide, or chew it.

This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Do not use any other NSAID unless your doctor says it is okay. Some other NSAIDs are aspirin, diflunisal, naproxen, or salsalate.

Some medicines can affect how this medicine works. Tell your doctor if you are using any of the following:

Warnings While Using This Medicine:

Tell your doctor if you are pregnant. Do not use this medicine during the later part of pregnancy.

Tell your doctor if you are breastfeeding or if you have kidney disease, liver disease, asthma, bleeding problems, heart or blood vessel problems, heart failure, a recent heart attack, high blood pressure, lupus, or a history of ulcers or other digestive problems. Tell your doctor if you smoke or drink alcohol.

This medicine may cause the following problems:

Increased risk of blood clots, heart attack, stroke, or heart failure

Bleeding problems, including stomach and bowel bleeding or ulcer

High blood pressure

Liver problems

Kidney problems

Serious skin reactions

Seizures

Changes in vision

Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.