DAMASCUS, Syria— Syria’s information minister says a chemical weapon fired by rebels on a village in the north of the country is the “first act” by the opposition interim government announced in Istanbul.

Omran al-Zoubi says the missile containing “poisonous gases” was fired from Nairab district in Aleppo into Khan al-Assal village on Tuesday.

He says 16 people were killed and 86 wounded in the attack. He spoke to the pro-government Al-Ikhbariya TV station.