Foster et al. show that inhibiting β-adrenergic signaling in the brain may restore respiratory function and prevent diaphragm atrophy in heart failure.

BONE REGENERATION

Bubbles and BMP-6 for bone repair

Bez et al. developed a two-step therapy to treat bone fractures by first implanting a collagen sponge at the fracture site that recruited progenitor cells and then injecting DNA encoding bone morphogenetic protein-6 (BMP-6) along with microbubbles that helped the progenitor cells take up BMP-6.