Though small, Landover houses many neighborhoods, which include Glenarden, Brightseat, Ardmore, Palmer Park, Kentland, Dodge Park, Columbia Park, Willow Hills (Hill Road), Belle Haven, Lansdowne, and Village Green. Metrorail's Orange Line passes through the community. Landover Hills is a separate, incorporated community a few miles away. Landover is the birthplace of the late Len Bias. From 1960 to 1972, Landover was the home of jazz guitarist and educator Steve Rochinski. The Prince Georges County Sports and Learning Complex is in Landover.

Landover is one of the few regions in the Washington DC area that is served directly by two separate Washington Metro rail lines. Landover is served by both the Orange and Blue lines (Many DC area suburbs are not served directly by Metrorail at all). The LandoverWashington Metro station serves the northern portion of Landover on the Orange Line. The Morgan Boulevard Metro station, constructed in 2004, serves the southern portion of Landover on the Blue Line and is the main rail terminus providing access to FedEx Field, which is home to the Washington Redskins in addition to many other sporting and entertainment events. In addition, there are many nearby Washington Metro rail stations in neighborhoods that border Landover, including the Addison Road Blue Line station in the bordering town of Seat Pleasant, the Cheverly Orange Line station in the bordering town of Cheverely, the Capital Heights Blue Line station in the bordering town of Captital Heights, the Largo Blue Line station in the bordering unincorporated area of Largo, and the Deanwood Orange Line station in the District of Columbia. Most of the above listed stations are within five Metro stops or less from the National Capital Building's Metro stop (Capital South Metro Station in the District of Columbia).

Landover was the home of Landover Mall, owned and operated by Lerner Enterprises. Built in 1972, it was the first enclosed mall in the Washington, DC metropolitan area to house four high-end retail anchor stores: Garfinkel's, Hecht's (owned by the May company), Woodward and Lothrop (popularly known as Woodies), and Sears. The mall also housed a multiplex movie theater located in the basement of the northeast corridor of the building. Located at the Capital Beltway and Landover Road, the mall neighbored the towns of Palmer Park, Ardmore, Glenarden, and Largo. Palmer Park was the hometown of legendary Olympic boxing champion Sugar Ray Leonard.

[12] Garfinkel's closed in 1990, Woodies closed in 1995 and was replaced with a short-lived J. C. Penney store that lasted from 1996 to 2001, and Hecht's closed in 2002 with the opening of the Bowie Town Center located in Bowie. The entire mall officially closed in 2003 and was subsequently demolished in 2006. Sears remains as the only free standing store.

With the arrival of FedEx Field, the home stadium for the Washington Redskins, in 1997, the mall's parking lot is used for overflow parking. In 2007, according to the Washington Post,[13] Prince George's County officials were in the midst of developing plans to transform the area where Landover Mall once stood. County officials propose to build luxury townhouses, trendy stores, and office buildings. The goal of the project is to transform the area into a residential and cultural hub that replicates the Bowie Town Center and The Boulevard at the Capital Centre located in Largo. Woodmore Towne Centre, featuring Costco and Wegmans, opened in 2010 in nearby Glenarden.

^In the late 1980s, crime began to rise in the surrounding areas and frightened shoppers eventually helped fuel the mall's rapid decline. The movie theater was the first to close, followed by three of the mall's anchor stores in the 1990s.