Fig. 4

Serum concentrations and medians of wheat and rice sIgG4 in children from the control group and in children with coeliac diseases and Helicobacter pylori infection. *wheat/rice: p < 0,05; Mann–Whitney test, **control group: children not suffering from atopy and gastrointestinal diseases in the upper part of the digestive tract (endoscopic and histological examination). The titers of wheat and rice sIgG4 were always more elevated in children with active celiac disease than in children with remission of celiac disease (p < .001). In children with active celiac disease the serum concentrations of wheat sIgG4 were higher than the rice-specific ones (p < .05), to remain the same in children with remission of celiac disease. In the children with the Helicobacter pylori infection the median wheat of sIgG4 were higher than that for rice (p < .05). Their serum concentrations of wheat sIgG4 were the same as in children with the remission of celiac disease