Symptoma

Histamine Intolerance

Presentation

The term “histamine intolerance” was coined by following the concept presented by lactose intolerance.[news.doccheck.com]

This allergy presents itself in a variety of ways such as a rash and anaphylaxis depending on your inherent sensitivity to it.[dnafit.com]

H3 receptors are present on cells of the central and peripheral nervous systems where histamine acts as a neurotransmitter.[histamine-sensitivity.com]

If you have histamine intolerance, you must avoid many foods: Histamine is present in a lot of products from eggs and cheese to meat and fish. If you don’t want to give up eating fish, here’s how to enjoy your meal without regret.[food.r-biopharm.com]

Within 26 months, 394 children presented with chronic abdominal … View Full Text Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service.[adc.bmj.com]

congestion and runny nose Conjunctivitis (irritated, watery, reddened eyes) Some types of headaches that differ from those of migraine Fatigue, confusion, irritability Very occasionally loss of consciousness usually lasting for only one or two seconds[greenmedinfo.com]

Gastrointestinal

The clinical evidence for histamine intolerance is based on chronic headache, diarrhoea, vomiting, flush, urticaria, asthma-like symptoms, rhinitis and others.[ncbi.nlm.nih.gov]

In fact, histamine intolerance can be responsible for conditions as diverse as seasickness, headaches and migraine, tachycardia, gastric disorders, diarrhea, intolerance to contrast media, parodontosis, period pains, nausea and vomiting in pregnancy,[bookdepository.com]

The following are mentioned as typical symptoms: Sudden skin redness (flush symptoms) Itching and redness on the body Digestive complaints such as nausea, vomiting, diarrhoea, abdominal pains Drop in blood pressure, dizziness, palpitations In women: menstrual[aha.ch]

Effects can range from common digestive system problems including abdominal pain and spasms, diarrhea, constipation, and flatulence, to headaches, to skin rash and eczema - all due to the body's inability to thoroughly digest food caused by the lack of[histame.com]

In fact, histamine intolerance can be responsible for conditions as diverse as seasickness, headaches and migraine, tachycardia, gastric disorders, diarrhea, intolerance to contrast media, parodontosis, period pains, nausea and vomiting in pregnancy,[bookdepository.com]

The ingestion of histamine-rich food or of alcohol or drugs that release histamine or block DAO may provoke diarrhea, headache, rhinoconjunctival symptoms, asthma, hypotension, arrhythmia, urticaria, pruritus, flushing, and other conditions in patients[ncbi.nlm.nih.gov]

Effects can range from common digestive system problems including abdominal pain and spasms, diarrhea, constipation, and flatulence, to headaches, to skin rash and eczema - all due to the body's inability to thoroughly digest food caused by the lack of[histame.com]

Details Headache, tachycardia, abdominal pain, flatulence, rash and itching may be signs of histamine intolerance. Histamine is responsible for the body’s defense against unwanted substances.[selfdiagnostics.com]

Effects can range from common digestive system problems including abdominal pain and spasms, diarrhea, constipation, and flatulence, to headaches, to skin rash and eczema - all due to the body's inability to thoroughly digest food caused by the lack of[histame.com]

In the SPC, the clauses “can cause asthma attacks” or “may lead to flush reactions” are well hidden. It’s a contentious matter that many drugs which are used by asthmatics inhibit DAO and other enzymes.[news.doccheck.com]

Histamine is an important mediator of allergic diseases such as hay fever and bronchial asthma, food allergies, urticaria, and drug hypersensitivity. Knowledge of histamine as a cause of numerous non-allergic symptoms and signs is, however, limited.[bookdepository.com]

The ingestion of histamine-rich food4 or alcohol4,5 may provoke heterogeneous symptoms and signs such as diarrhea, headache,5 rhinoconjunctivitis, asthma, hypotension,4,6,7 arrhythmia, urticaria, pruritus, and flushing.8 Additionally, several drugs have[journals.sagepub.com]

The patients with pruritus had elevated histamine (20.7 nmol/l), compared with the patients without pruritus (4.2) and normal subjects (2.1).[selfhacked.com]

The ingestion of histamine-rich food or of alcohol or drugs that release histamine or block DAO may provoke diarrhea, headache, rhinoconjunctival symptoms, asthma, hypotension, arrhythmia, urticaria, pruritus, flushing, and other conditions in patients[ncbi.nlm.nih.gov]

This makes it difficult to differentiate between histamine excess and allergy. diarrhea headache rhinoconjunctival symptoms asthma hypotention arrhythmia urticaria pruritus flushing Foods high in histamine include fermented products such as wine, dry[naturalhealthmedicine.com.au]

Neurologic

One slice of yeasted bread or a glass of white wine and the next day the nausea and headache are back. The hardest thing about HIT is getting a diagnosis.[telegraph.co.uk]

Details Headache, tachycardia, abdominal pain, flatulence, rash and itching may be signs of histamine intolerance. Histamine is responsible for the body’s defense against unwanted substances.[selfdiagnostics.com]

The clinical evidence for histamine intolerance is based on chronic headache, diarrhoea, vomiting, flush, urticaria, asthma-like symptoms, rhinitis and others.[ncbi.nlm.nih.gov]

Workup

Serum

It decreases anxiety, increases serotonin, increases dopamine, and is useful for the treatment of OCD [ 52, 53 ].[selfhacked.com]

Treatment

Aside from dietary changes, there is no set treatment for people with histamine intolerance. But most people with the condition benefit from a few different medical treatments, depending on their symptoms or the cause of the condition.[medicalnewstoday.com]

Finally he also deals with the issue of treatments for DAO deficiency and the intolerance to histamine.[dr-healthcare.com]

Prognosis

What is the long-term outlook (prognosis)? The prognosis is very variable. Not everyone progresses from stage 1 to stage 3. For many affected people, hidradenitis suppurativa is a painful and debilitating condition.[patient.info]

HIT is more widely accepted in Europe as a true condition and was recognized in 2012 by the German Society for Allergology and Clinical Immunology as a true disease for which the pathophysiology has yet to be determined.[theceliacmd.com]

Prevention

Therefore, the same amount of histamine will be circulating in the body as before taking the antihistamine; it is simply prevented from exerting its effects.[histamine-sensitivity.com]

Antihistamine drugs exert their effects by blocking the combination of histamine with these receptors or by halting the release of histamine, thereby preventing the allergic reaction.[accessscience.com]

HIT is a pathological process, in which the enzymatic activity of histamine-degrading enzymes is decreased or inhibited and they are insufficient to inactivate histamine from food and to prevent its passage to blood-stream.[dr-healthcare.com]