Blockchain is the hot new technology topic in the financial world, the health sector, and the supply chain industry. The idea, first applied by the virtual “cryptocurrency” Bitcoin, combines the security of cryptography with the safety of distributed data. Blockchain technology has a variety of applications in health, not least of which are medicine traceability and patient data management. This is just as true for the US domestic health sector as it is for health systems in low- and middle-income countries (LMICs).