Magnesium could prevent fractures, say researchers - Science Daily, 4/12/17
- "Bone fractures are one of the leading causes of
disability and ill health especially among the aging population and this
increases the burden on the health care system. It is well-known that calcium
and vitamin D play an important role in bone health. Magnesium is an essential
nutrient and is an important component of the bone ... The risk of having a
fracture was reduced by 44 per cent in men with higher blood levels of
magnesium. None of the 22 men who had very high magnesium levels (> 2.3 mg/dl)
in the study population experienced a fracture during the follow-up period"
- See
Magtein at Amazon.com.
I take two with each meal.

More Fractures Seen When
Vitamin D Is Consistently Low - Medscape, 4/15/14 -
"Adequate levels of vitamin D help increase calcium absorption from the gut, and
both calcium and vitamin D are important in terms of bone health ... The
remaining question, said Dr. Judge, is "Would intervening with the women with
the lowest 25OHD levels decrease their risk of fractures?" He continued, "I
believe the evidence suggests that the answer is yes. The working hypothesis is
that vitamin D reduces fractures in elderly people by improving balance and
reducing the risk of falls, rather than through its effect on bone density.""
- See
Vvitamin D at Amazon.com.

Impact
of long-term vitamin D insufficiency on fracture risk - Science Daily,
4/4/14 - "Study participants at baseline were 1044 Swedish women, all aged 75,
with 715 attending at the 5-year follow up. Serum 25-hydroxyvitamin D (25OHD)
levels (nmol/l) were classified as low (<50), intermediate (50 ) and high (>75)
... the incidence of hip fractures within 10 years was significantly lower in
those women who were vitamin D sufficient (≥50 nmol/l) at baseline and
maintained this level at 5 years. The proportion of women sustaining FRAX
fractures was 26.2% and 30% in the group which had consistently high or
intermediate 25OHD levels compared to 45.6 % in the group with consistently low
levels" - See
vitamin D at Amazon.com.

Calcium + Vitamin D:
Surprises From Long-term Follow-up - Medscape, 12/11/13 -
"the analyses that were limited to adherent women who
were taking at least 80% of their study pills compared with the women who were
taking at least 80% of their placebo pills showed a statistically significant
29% reduction in the risk for hip fracture ... Also shown in the new report is
that with longer-term follow-up, a statistically significant reduction in in
situ breast cancer emerged -- a 13% reduction overall ... In terms of all
cancers, among the women who had low baseline intake of vitamin D, there was a
statistically significant 9% reduction in total cancer with supplementation, and
also a marginally significant 9% reduction in all-cause mortality" - See
vitamin D at Amazon.com.

Intake and
serum concentrations of α-tocopherol in relation to fractures in elderly women
and men: 2 cohort studies - Am J Clin Nutr. 2013 Nov 13 -
"Two cohort studies, the Swedish Mammography Cohort
(SMC; n = 61,433 women) and the Uppsala Longitudinal Study of Adult Men (ULSAM;
n = 1138 men), were used ... A higher hip fracture rate was observed with lower
intakes of α-tocopherol. Compared with the highest quintile of intake, the
lowest quintile had a multivariable-adjusted HR of 1.86 (95% CI: 1.67, 2.06).
The HR of any fracture was 1.20 (95% CI: 1.14, 1.28). α-Tocopherol-containing
supplement use was associated with a reduced rate of hip fracture (HR: 0.78; 95%
CI: 0.65, 0.93) and any fracture (HR: 0.86; 95% CI: 0.78, 0.94). Compared with
the highest quintile of α-tocopherol intake in ULSAM (follow-up: 12 y), lower
intakes (quintiles 1-4) were associated with a higher rate of hip fracture (HR:
3.33; 95% CI: 1.43, 7.76) and any fracture (HR: 1.84; 95% CI: 1.18, 2.88). The
HR for hip fracture in men for each 1-SD decrease in serum α-tocopherol was 1.58
(95% CI: 1.13, 2.22) and for any fracture was 1.23 (95% CI: 1.02, 1.48)"
- See
Jarrow FamilE (contains all eight members of the vitamin E family, includes
Tocomin) at Amazon.com.

Protective
effects of dietary carotenoids on risk of hip fracture in men: The Singapore
Chinese Health Study - J Bone Miner Res. 2013 Jul 16 -
"used data from the Singapore Chinese Health Study, a
prospective cohort of 63,257 men and women who were of ages 45-74 years between
1993 and 1998 ... validated food frequency questionnaire. During a mean
follow-up of 9.9 years, we identified 1,630 hip fracture incident cases. Among
men, consumption of vegetables was associated with lower hip fracture risk.
Similarly, dietary total carotenoids and specific carotenoids, α-, β-carotene
and lutein/zeaxanthin were inversely associated with hip fracture risk. Compared
to men in the lowest quartile of nutrient density, men in the highest quartile
had statistically significant 26% to 39% risk reduction ... There was no
association between dietary carotenoids or vegetables/fruits and hip fracture
risk among women. This study suggests that adequate intake of vegetables may
reduce risk of osteoporotic fractures among elderly men and that the antioxidant
effects of carotenoids may counteract the mechanism of osteoporosis related to
leanness" - See
Jarrow Formulas, CarotenALL at Amazon.com.

Could a
Diet High in Fish and Flax Help Prevent Broken Hips? - Science Daily,
6/27/13 - "The study showed that higher levels of
omega-3 fatty acids from both plant and fish sources in those blood cells were
associated with a lower likelihood of having fractured a hip ... The study also
showed that as the ratio of omega-6 fatty acids to omega-3s increased, so did
the risk for hip fracture ... Inflammation is associated with an increased risk
of bone loss and fractures, and omega-3 fatty acids are believed to reduce
inflammation ... omega-3 fatty acids have anti-inflammatory properties and
omega-6 fatty acids seem to have both anti- and pro-inflammatory effects ...
women who had the highest ratio of omega-6 to omega-3 fatty acids had nearly
twice the risk of hip fractures compared to women with the lowest ratios. The
current typical American diet contains between 15 and 17 times more omega-6 than
omega-3, a ratio that previous research has suggested should be lowered to
4-to-1, or even 2-to-1, by increasing omega-3s, to improve overall health. The
primary omega-6 fatty acid in the diet is linoleic acid, which composes about 99
percent of Americans' omega-6 intake and is found in corn, soybean, safflower
and sunflower oils" -
See
Mega Twin EPA at Amazon.com
and
Jarrow Max DHA at Amazon.com.

Low serum
levels of 25-hydroxyvitamin D predict hip fracture in the elderly. A NOREPOS
study - J Clin Endocrinol Metab. 2013 May 15 - "risk
of hip fracture in Norway, a high-latitude country that has among the highest
hip fracture rates worldwide ... We observed an inverse association between
s-25(OH)D and hip fracture; those with s-25(OH)D in the lowest quartile (<42.2
nmol/l) had a 38% (95% CI 9-74%) increased risk of hip fracture compared with
the highest quartile ... In this prospective case-cohort study of hip fractures,
the largest ever reported, we found an increased risk of hip fracture in
subjects in the lowest compared to the highest quartile of serum
25-hydroxyvitamin D" - See
vitamin D at Amazon.com.

Dietary
patterns and the risk of hip fractures in elderly Chinese: A matched
case-control study - J Clin Endocrinol Metab. 2013 Apr 12 -
"Face-to-face interviews were conducted to assess
dietary intake using a 79-item food frequency questionnaire ... We identified
four dietary patterns: healthy, prudent, traditional, and high fat.
Dose-dependent lower risks of hip fracture were observed in relation to higher
scores in the healthy dietary pattern related to high fruit and vegetable
intake, and in the prudent pattern typified by a higher intake of nuts,
mushrooms, algae, and seafood but lower in grains, whereas the same were
associated with lower scores in the high fat dietary pattern (all P trend
<0.05). The adjusted ORs (95% CIs) for hip fractures, comparing the extreme
tertiles of the three patterns, were 0.42 (0.24-0.73) for healthy, 0.51
(0.28-0.90) for prudent, and 2.25 (1.38-3.69) for high fat"

Cartenoids found to reduce hip fracture risk in lean men - Science Daily,
12/16/12 - "Elderly who are lean (BMI <20 kg/m2) are at
higher risk of hip fracture compared to those with higher BMI ... researchers
examined the association between dietary antioxidant carotenoids and hip
fracture risk across a range of BMI in elderly Chinese men and women using data
from the Singapore Chinese Health Study ... low BMI is a stronger risk factor
for hip fracture risk among elderly men compared to women ... Also, in men, hip
fracture risk decreased with increasing intakes of total vegetables and of total
carotenoids, particularly β-carotene" - See
Jarrow Formulas, CarotenALL at Amazon.com.

High
physical fitness in young adulthood reduces the risk of fractures later in life
in men: A nationwide cohort study - J Bone Miner Res. 2012 Nov 26 -
"Aerobic capacity and isometric muscle strength were
measured in 435445 Swedish men that conscripted for military service from
1969-1978 ... When comparing men in the lowest and highest decile of physical
fitness, the risk of a fracture was 1.8 times higher (95% CI = 1.6-2.1) and that
of hip fracture was 2.7 times higher (95% CI = 1.6-4.7). The risk of fracture
was also 1.4-1.5 times higher when comparing the extreme deciles of muscle
strength (p < 0.001 for all). In a subcohort of 1009 twin pairs, up to 22% of
the variation in physical fitness and 27-39% of the variation in muscle strength
was attributable to environmental factors unique to one twin, e.g. physical
activity. In conclusion, low aerobic capacity and muscle strength in young
adulthood are associated with an increased risk of low-energy fractures later in
life, while a low-energy fracture is associated with an increased risk of death
already in middle-aged men"

Joint
failures potentially linked to oral bacteria - Science Daily, 4/18/12 -
"The culprit behind a failed hip or knee replacements
might be found in the mouth. DNA testing of bacteria from the fluid that
lubricates hip and knee joints had bacteria with the same DNA as the plaque from
patients with gum disease and in need of a joint replacement ... it might be the
reason why aseptic loosening or prosthetic wear of the artificial joints fail
within 10 years when no infection appears to be present ... For a long time,
we've suspected that these bacteria were causing problems in arthritis patients,
but never had the scientific evidence to support it" - See
Xlear Spry Peppermint Gum, 600-Count (Made with 100% xylitol)
at Amazon.com.

A Randomized
Controlled Trial of Vitamin D Dosing Strategies After Acute Hip Fracture -
Medscape, 9/12/11 - "Our findings reveal that a simple
daily 1,000 IU vitamin D3 dosing regimen may be as effective as a regimen that
adds a loading dose of vitamin D2 to daily vitamin D3 for increasing 25-OHD
levels as early as 4-weeks. However, more than 25% of all study patients taking
1,000 IU vitamin D3 (with or without the loading dose) still did not achieve the
target 25-OHD level of at least 75 nmol/L. Future studies should examine higher
daily doses of vitamin D3 (i.e. 2,000 IU) as well as the benefits of an
additional loading dose in patients who are severely deficient" - See
vitamin D at Amazon.com.

Before
you start bone-building meds, try dietary calcium and supplements, experts urge
- Science Daily, 5/2/11 - "For many people, prescription
bone-building medicines should be a last resort ... adults who increase their
intake of calcium and vitamin D usually increase bone mineral density and reduce
the risk for hip fracture significantly ... I suspect that many doctors reach
for their prescription pads because they believe it's unlikely that people will
change their diets ... prescription bone-building medications are expensive, and
many have side effects, including ironically an increase in hip fractures and
jaw necrosis. They should be used only if diet and supplements don't do the
trick ... For bone health, the researchers also encourage consuming adequate
protein, less sodium, and more magnesium and potassium"

Vitamin D
Treatment for the Prevention of Falls in Older Adults - Medscape,
9/30/10 - "In summary, vitamin D supplementation is
an effective strategy for reducing falls in older adults and should probably
be incorporated into the clinical practice of providers caring for older
adults, especially those at risk for falling. Although the effect appears to
be modest, possibly because of inadequate dosing, vitamin D is inexpensive
and well tolerated; a slight reduction in falls with vitamin D
supplementation might lead to a significant decrease in the costs associated
with fall morbidity and mortality" - See
vitamin D at Amazon.com.

Dietary protein may reduce hip fractures in the elderly - Science Daily,
5/5/10 - "individuals who were in the lowest 25
percent of dietary protein intake had approximately 50 percent more hip
fractures than those who consumed greater amounts of dietary protein (all
within normal intakes). Those who suffered hip fractures consumed less than
the 46 grams of dietary protein per day recommended for adults"

Carotenoids linked to fewer hip fractures - Nutra USA, 3/26/09 -
"higher lycopene intake was associated with a lower
risk of hip fracture, and non-vertebral fracture ... a weak but
statistically un-significant protective trend was recorded total
beta-carotene, but only for hip fractures ... No protective effects were
observed for the other carotenoids" - [Abstract]
- See
lycopene at Amazon.com.

Folate and Vitamin
B12 Prevent Hip Fracture in Stroke Patients - Medscape, 3/25/05 -
"The magnitude of benefit is similar to that found in trials of alendronate
and raloxifene, with considerably less potential risk. The fact that BMD did
not change suggests the benefit derives from quality, rather than quantity,
of bone"

Vitamin A Levels Affect Hip Fracture Risk - Physician's Weekly, 10/4/04
-
"women with the lowest concentrations of
vitamin A had a 90% higher risk of hip
fracture. Those with the highest concentrations were twice as likely as
those with normal levels to sustain a hip fracture"

Maker Aware of 40% Failure in Hip Implant - NYTimes.com, 1/23/13 -
"An internal analysis conducted by Johnson & Johnson
in 2011 not long after it recalled a troubled hip implant estimated that the
all-metal device would fail within five years in nearly 40 percent of
patients who received it, newly disclosed court records show"

Public Kept in Dark
About Hip-Replacement Risks, Says BMJ - Medscape, 2/28/12 -
"The wear and tear of metal on metal releases metal
ions that can seep into local tissue, destroy muscle and bone, and leave
patients with long-term disabilities ... These metal ions, which may be
carcinogenic, also can become blood-borne and spread to the lymph nodes,
spleen, liver, and kidneys"

Knee Replacement Can
Lead to Longer Life - Medscape, 2/10/12 -
"Patients with severe osteoarthritis of the knee who undergo knee
replacement have a 7-year mortality rate that is half that of those who
don't undergo the procedure ... Also, those with knee replacements had a
slightly lower rate of heart failure at 3 years (21.1%; HR, 0.89; P < .001)
and at 7 years (40.9%; HR, 0.93; P < .001)"

Complaints Soar on Hip Implants as Dangers Are Studied - NYTimes.com,
8/23/11 - "the Food and Drug Administration has
received more than 5,000 reports since January about several widely used
devices known as metal-on-metal hips, more than the agency had received
about those devices in the previous four years combined ... Though immediate
problems with the hip implants are not life-threatening, some patients have
suffered crippling injuries caused by tiny particles of cobalt and chromium
that the metal devices shed as they wear ... As problems and questions grow,
most surgeons are abandoning the all-metal hips, saying they are unwilling
to expose new patients to potential dangers when safer alternatives — mainly
replacements that combine metal and plastic components — are available"

Heavy metal: Titanium implant safety under scrutiny - Science Daily,
7/25/11 - "Titanium implants are routinely used for
bone fractures as well as dental work. It has recently been shown that
titanium-based implants both corrode and degrade, generating metallic
debris. There is some concern over the increased concentrations of
circulating metal-degradation products derived from these implants, and
their potential harmful biological effects over a period of time, including
hepatic injury and renal lesions"