The main areas of interest are: (i) structure of bone proteins relevant to osteoporosis, (ii) platelet glycoprotein interactions in hemostasis and thrombosis, (iii) designing therapeutic inhibitors for LOX-1, a receptor for oxidized LDL, (iv) interactions of methamphetamine and its metabolites with a therapeutic antibody, and (v) structures of proteins involved in bacterial cell wall synthesis.

Affinity improvement of a therapeutic antibody to methamphetamine and amphetamine through structure-based antibody engineering. (a) The binding interactions of the wild-type antibody; (b) Interactions of the S93T mutant.