Western Blot (1-10µg/ml)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.

Application Notes:

Detects a band of ~53kDa by Western blot.

Purity Detail:

Peptide affinity purified.

Formulation:

Liquid. In PBS containing 0.08% sodium azide.

Shipping:

Shipped on Blue Ice

Long Term Storage:

-20°C

Scientific Background:

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to Mdm2, SV40 T antigen and human Papilloma virus E6 protein. p53 senses DNA damage and facilitates its repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovary, bladder, colon, lung, and melanoma.