Before treatment:
Sufian developed weakness in his lower limbs 4 years ago, and this condition progressively became worse. He also had muscular atrophy as well as contracture deformity in both ankles after an injury of both lower limbs, which was relieved 6 months later. His upper limbs became weaker 1 year later. There was contracture deformity in the dorsum of both hands. He was not able to make a fist. There was genetic testing done and the results showed he had muscular dystrophy (2013.4.24), so he took medication and did some rehabilitation training but there was no improvement. His condition became worse. He is able to walk slowly now, but gets easily tired. He needs some help to walk up stairs. All four limbs have distal muscular contractures. His muscle power is lower than normal. The skin on his lower limbs was dry. Sufian was in good spirits. His diet and sleep are good. The bowel movements and urination are normal. He had lost around 4 Kgs since the onset of the disease. The CK level was higher than normal.

Admission PE:
Bp: 121/80mmHg; Hr: 78/min. Temperature: 36.0 degrees. Height: 163 cm, weight: 49.g Kg. Abnormal walking steps. There were no yellow stains or petechia on the skin or mucous. The respiration in the base of both lungs was weaker than normal, the respiration in both lungs was clear. There were no dry or moist rales. The rhythm of the heartbeat was normal with no obvious murmur in the valves. The abdomen was soft with no pressing pain or rebound tenderness. The liver and spleen were normal. There was no edema in the lower limbs. He had physiological curvature of the spinal column.

Nervous System Examination:
Sufian Subri Khan was alert and in good spirits. His speech was clear His memory, calculation ability, comprehension and orientation were normal. Both pupils were equal in size and round, the diameter was 3 mms, both eyes had sensitive responses to light stimuli. Both eyeballs could move freely. The nasolabial fold and forehead wrinkle pattern was symmetrical. He could close his eyes strongly. The tongue was centered in the oral cavity. There was no deflection of the teeth. When the cheeks were expanded, there was no leakage of air. He was able to raise the soft palates powerfully. He could turn his head flexibly and could shrug his shoulders powerfully. The muscle power of both upper limbs was at level 4+, both lower limbs was at level 4-, the muscle tension of all four limbs was lower than normal. The ankle joints had slight contracture deformity. The dorsum of both hands also had contracture deformity so he was not able to make a fist. The right biceps brachii reflex was normal. The bilateral radial periosteal reflex, triceps brachii reflex, left biceps brachii reflex, patellar tendon reflex of both lower limbs and ankle reflex were abnormal. The abdominal reflex was normal. The bilateral palm jaw reflex, Hoffmann’s sign, Rossolimo’s sign and Babinski’s sign were negative. The pain sensation was sensitive. He was able to do the finger-to-nose test and rapid rotation test. He was not able to do the heel-knee-tibia test. The Romberg’s sign was positive. The meningeal irritation sign was negative. Biopsy of the right vastus lateralis(2013.5): compatibility muscular dystrophy.

Treatment:
Sufian was diagnosed with muscular dystrophy. He received 3 neural stem cell injections and 3 mesenchymal stem cell injections to repair his damaged cells and regenerate new normal cells, activate the stem cells in his body, improve his blood circulation, regulate his immune system, nourish the muscle cells and repair his muscle fibers. We also gave him daily physical rehabilitation.

Post-treatment:
After 15 days of treatment, Sufian got stronger, his physical endurance increased, he felt more comfortable with the dorsum of the hand and hip joints, he was able to move his ankle joints better, his steps improved. The muscle power of his upper limbs was at level 5-, the muscle power of his lower limbs was at level 4+. The CK level was lower than normal.