The underlying motivation for our research is the need for a deeper understanding of human-computer interaction that can speak to the increasingly varied and intricate forms of interactivity and interfaces that are present ...

Much life science and biology research requires an understanding of complex relationships between biological entities (genes, compounds, pathways, diseases, and so on). There is a wealth of data on such relationships in ...

The overwhelming amount of available scholarly literature in the life sciences poses significant challenges to scientists wishing to keep up with important developments related to their research, but also provides a useful ...

Background: Semantic Web Technology (SWT) makes it possible to integrate and search the large volume of life science datasets in the public domain, as demonstrated by well-known linked data projects such as LODD, Bio2RDF, ...

To communicate a design can be seen as consisting of at least two aspects: presentation and argumentation. In our research we have taken on the task of studying how practicing interaction designers approach the challenge ...

The modular organization of networks of individual neurons interwoven through synapses has not been fully explored due to the incredible complexity of the connectivity architecture. Here we use the modularity-based community ...

Background: Systems chemical biology and chemogenomics are considered critical, integrative disciplines in modern biomedical research, but require data mining of large, integrated, heterogeneous datasets from chemistry and ...

Blevis, Eli(Indiana University School of Informatics and Computing, 2011)

Some disciplines focus on analytic research and some disciplines focus on synthesis. Design disciplines are interesting because designers need to do both analysis and synthesis tasks. The HCI & design program I presently ...

The goal of the Human Microbiome Project (HMP) is to generate a comprehensive catalog of human-associated microorganisms including reference genomes representing the most common species. Toward this goal, the HMP has ...

Relating chemical features to bioactivities is critical in molecular design and is used extensively in the lead discovery and optimization process. A variety of techniques from statistics, data mining and machine learning ...

Relating chemical features to bioactivities is critical in molecular design and is used extensively in the lead discovery and optimization process. A variety of techniques from statistics, data mining and machine learning ...

We analyze the online response to the preprint publication of a cohort of 4,606 scientific articles submitted to the preprint database arXiv.org between October 2010 and May 2011. We study three forms of responses to these ...

Background: Long terminal repeat (LTR) retroelements represent a successful group of transposable elements (TEs)that have played an important role in shaping the structure of many eukaryotic genomes. Here, we present a ...

The use of quantitative metrics to gauge the impact of scholarly publications, authors, and disciplines is predicated on the availability of reliable usage and annotation data. Citation and download counts are widely ...

The NIH Human Microbiome Project (HMP) has produced several hundred metagenomic data sets, allowing studies of the many functional elements in human-associated microbial communities. Here, we survey the distribution of ...

The rapidly increasing amount of public data in chemistry and biology provides new opportunities for large-scale data mining for drug discovery. Systematic integration of these heterogeneous sets and provision of algorithms ...

Beckwith, Lee(Indiana University School of Informatics and Computing, 2012)

Qualitative research methodologies were used in order to better understand how well currently available mobile phone interfaces are designed to match the way Japanese is thought of by native speakers. A conceptual design ...