Overview

Jones syndrome is a very rare condition characterized by gingival fibromatosis (enlargement and overgrowth of the gums) and progressive, sensorineural hearing loss.[1] The onset of gingival fibromatosis usually occurs with the eruption of the permanent teeth. Excessive growth of the gums may cause displacement of teeth, over-retention of primary teeth, and increased spacing.[2] Jones syndrome is inherited in an autosomal dominant manner, but the underlying genetic cause is not yet known.[1] Only a few families with Jones syndrome have been reported.

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In Depth Information

Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.

Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.

PubMed is a searchable database of medical literature and lists journal articles that discuss Jones syndrome. Click on the link to view a sample search on this topic.

Other Names for this Disease

Familial gingival fibromatosis associated with progressive deafness

GFD

Gingival fibromatosis with progressive deafness

Gingival fibromatosis - progressive deafness

Gingival fibromatosis with sensorineural hearing loss

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