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Strain, a graduate of Diablo Valley College, had an extensive athletic background. Much of her youth was wiped from her memory, however, when she was left with a case of amnesia due to a fall from a horse, which caused a severe head injury. She eventually made her way to Las Vegas and later Hollywood and her career took off.

Strain has come to be known as the "Queen of the B-movies". She has over one hundred films to her credit. In addition, she was Penthouse Pet of the Month for June 1991, and Penthouse Pet of the Year for 1993. She has also had her likeness attached to numerous comic book characters and animation items. For example, she did the voice acting for the main character in the animation movie Heavy Metal 2000 and was the basis for the third person shooter Heavy Metal: F.A.K.K.².

Strain, who stands 6 ft 1 in (1.85 m), is married to Teenage Mutant Ninja Turtles co-creator Kevin Eastman. Eastman is also the Editor in Chief of Heavy Metal magazine.[2] Julie often appears in the magazine in photos or pictures painted by her close friends Olivia De Berardinis and Simon Bisley.

She also became very popular for performing in the program Sex Court on Playboy TV.
She is currently the owner of the original Batmobile from the 1960s live action Batman television series.