HIGH RESOLUTION OPTICS(Navitar Zoom6000 mounted on a Jenoptik ProgRes SPEED XT CCD Camera)
Gives the possibility to use the Monitor of the PC to look at the images of the donor blocks, at the glass slide with a good resolution an x20 magification.
It is used to save the images of the glass slide which can be used later for virtual image sovraimposition and/or to be inserted into the digital report.

AUTOMATED AND COMPUTER-GUIDED NEEDLE POSITIONINGThe needles are changed and positioned automatically during the TMA construction process to:
*avoid errors that could endanger the TMA quality
*Help the operator in the TMA construction
*speed up the process
*Regulate accurately the punching depth.

UP-TO-6 BLOCK AUTOMATED TRAY(Prior Scientific ES111 OptisScan)
Ensure precise positioning of the paraffin blocks under the needles
Recipient and Donor tissue blocks can be positioned in any of the 6 positions

MACRO-BLOCK HOLDER(only for Galileo CK3500 Advanced)
Possibility to mount simultaneously one macro-cassette and up to three standard cassettes on the automated tray
Use the macro-block both as donor and recipient block

The IseNet User interface is designe to semplify the Tissue Microarray design and construction supporting the Pathologist in all phases of the TMA process. It is constituted by the following modules:

1.TEMPLATE EDIT*Define the paraffin area size
*Define the needle diameter, the number of spots, the spacing between the spots
*Introduce rows or column or spots as spacing
*Create a library of TMA templates

2.TMA DESIGN*Define the donor blocks
*Associate each donor block to the corresponding spot(s)
*Assign a colour to the spots
*Define the table moving sequence
*Define the number of replicas

3.TMA CONSTRUCTIONThe construction of the TMA is supported by a flow chart on the screen, which guides the operator though each step:
Step 1: Load the “Design File”
Step 2: Identify the punch are by:
Manual Overlapping
Overlap the reference slide to the donor block
Align the images looking into the monitor
Save the punch positions

Digital overlapping
Capture the image of the reference slide
Adjust the live image of the donor block
Overlap the images
Align the images
Save the punch positions clicking the mouse

Follow the instruction on the flow chart to construct your array easy and reliable.

4.DIGITAL REPORTINGCreate the final report of the array in an Excel spread-sheet
Properly identify each spot during subsequent analyses
Relate each spot to the corresponding information
Personalize the report
Associate the clinico-pathological data to the corresponding donor blocks
Add the results of the analyses
Insert images