Fundamental studies concerning the development of super functional biosensers were performed. In the development of super functional enzyme sensor, use of artificial enzyme was thought to be effective. In the development of optical-super functional biosensor, reduction of noise from matrix was thought to be important, and the solution was presumed to be attained by the use of pretreatment equipment. In the development of micro-super functional biosensor, France side required more information to Japan side. In the development of medical and environmental super functional biosensor, SPR device was thought to be useful, but the price of the device needed to be reduced.