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PvP.Patch Kernel Issue

Hi all. I'm having the problem with this issue since yesterday. When I go to play League of Legends, it just opens LoL logo, stands there for 5 seconds, after that it opens popup saying

"Another instance of the launcher is running. Do you want to terminate it?"
with Yes or No options.

If I click No; the logo & popup closes. Like I closed LoL.
If I click Yes; the logo stays and popup goes away, but after about 5 more seconds the logo gets an error saying that PvP.Patcher Kernel has stopped working. I have options to find solution on internet and close, wait for program's response and close the program.

If I click 1st or 3rd option it quits.
If 2nd option is chosen, then it waits til I click on it again and then it just repeats.

Hi all. I'm having the problem with this issue since yesterday. When I go to play League of Legends, it just opens LoL logo, stands there for 5 seconds, after that it opens popup saying

"Another instance of the launcher is running. Do you want to terminate it?"
with Yes or No options.

If I click No; the logo & popup closes. Like I closed LoL.
If I click Yes; the logo stays and popup goes away, but after about 5 more seconds the logo gets an error saying that PvP.Patcher Kernel has stopped working. I have options to find solution on internet and close, wait for program's response and close the program.

If I click 1st or 3rd option it quits.
If 2nd option is chosen, then it waits til I click on it again and then it just repeats.

This is just a wild quess but what kind of antivirus and firewall softwares are you using?
I had somewhat similar problem with my Starcraft 2 when my firewall (Comodo Internet Security) had Defense+ active.
Game just stoped responding right after start even though it was already a "trusted process" and firewall was in "game mode".

If one of your softwares had similar ability to protect system files from anything it doesn't recognize this could be a cause of problem.

This is just a wild quess but what kind of antivirus and firewall softwares are you using?
I had somewhat similar problem with my Starcraft 2 when my firewall (Comodo Internet Security) had Defense+ active.
Game just stoped responding right after start even though it was already a "trusted process" and firewall was in "game mode".

If one of your softwares had similar ability to protect system files from anything it doesn't recognize this could be a cause of problem.

Move your game files to C:/Riot Games. This might fix your problem. If it doesn't uninstall them, and reinstall to the C:/ drive