Molecular Biology of Hematopoiesis 5

Synopses & Reviews

Publisher Comments

These papers as a whole consist of an excellent overall review of the basic, preclinical and clinical up-to-date knowledge in the field of cell therapy...Readers will obtain not only up-to-date knowledge of the pathophysiology of hematopoiesis and hematological diseases, but also see the future strategies of novel therapeutic approaches for these diseases. --- International Journal of Hematology, 1998 Many recent findings are presented, as are the laboratory protocols used in these investigations. The book is recommended for all clinical and basic science investigators entering the field of hematopoietic studies. It also presents many important views for the consideration of established investigators. --- The Quarterly Review of Biology, June 1998

Synopsis

This volume of Molecular Biology of Hematopoiesis is dedicated to John W. Adam- son, M. D., Tadamitsu Kishimoto, M. D., Robert C. Gallo, M. D., Arthur W. Nienhuis, M. D., and Franco Mandelli, M. D., for their contributions in developing an overall view of the state-of-the-art knowledge in the field of hematopoiesis. Richard Champlin, among other renowned clinicians, presented updated information on stem cells and T-cell depletion for bone marrow transplant. A clinical update on thrombopoietin was presented by Pamela Hunt of Amgen and by Kenneth Kaushansky. Arthur Nienhuis' and Katherine Turner's contribu- tions to our current knowledge and advances in the fields of growth factors and gene transfer were also recognized during the 9th Symposium on Molecular Biology of Hematopoiesis in Genoa. The chapters cover such diverse areas as preclinical and clinical updates on growth factors and positive and negative regulatory molecules. "Advances in Leukemia: Mechanism and Treatment by Interferon" was presented by Professor Sante Tura. Readers will find presentation of exciting advances that have occurred in the area of hematopoiesis. The elucidation of gene structures of key growth factor proteins such as IL-12 and IL-II will lead to new insights and new approaches in understanding the regulation of hematopoiesis, as well as application of new growth factors.