Immune Tolerance

Synonyms

Immunosuppression (Physiology)

Immunosuppressions (Physiology)

Tolerance, Immune

The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.