STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RB2654_03414

Aminotransferase, classes I and II (379 aa)

Predicted Functional Partners:

RB2654_08672

Aminomethyl transferase family protein (833 aa)

0.893

RB2654_19533

Uncharacterized protein (627 aa)

0.880

RB2654_15060

Anthraniloyl-CoA monooxygenase (764 aa)

0.864

gcvP

Glycine dehydrogenase (aminomethyl-transferring) ; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (953 aa)

0.862

RB2654_21303

Homoserine dehydrogenase (430 aa)

0.859

RB2654_18683

Bifunctional protein PutA ; Oxidizes proline to glutamate for use as a carbon and nitrogen source (1138 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

RB2654_03409

RB2654_03414

RB2654_03409

RB2654_03414

27 kDa outer membrane protein, putative

Aminotransferase, classes I and II

0.746

RB2654_03409

RB2654_15060

RB2654_03409

RB2654_15060

27 kDa outer membrane protein, putative

Anthraniloyl-CoA monooxygenase

0.414

RB2654_03414

RB2654_03409

RB2654_03414

RB2654_03409

Aminotransferase, classes I and II

27 kDa outer membrane protein, putative

0.746

RB2654_03414

RB2654_08302

RB2654_03414

RB2654_08302

Aminotransferase, classes I and II

Prephenate dehydrogenase

0.787

RB2654_03414

RB2654_08672

RB2654_03414

RB2654_08672

Aminotransferase, classes I and II

Aminomethyl transferase family protein

0.893

RB2654_03414

RB2654_10094

RB2654_03414

RB2654_10094

Aminotransferase, classes I and II

Prephenate dehydratase

0.783

RB2654_03414

RB2654_15060

RB2654_03414

RB2654_15060

Aminotransferase, classes I and II

Anthraniloyl-CoA monooxygenase

0.864

RB2654_03414

RB2654_18683

RB2654_03414

RB2654_18683

Aminotransferase, classes I and II

Bifunctional protein PutA ; Oxidizes proline to glutamate for use as a carbon and nitrogen source

0.857

RB2654_03414

RB2654_19533

RB2654_03414

RB2654_19533

Aminotransferase, classes I and II

Uncharacterized protein

0.880

RB2654_03414

RB2654_19638

RB2654_03414

RB2654_19638

Aminotransferase, classes I and II

Serine--glyoxylate transaminase, putative

0.767

RB2654_03414

RB2654_21303

RB2654_03414

RB2654_21303

Aminotransferase, classes I and II

Homoserine dehydrogenase

0.859

RB2654_03414

gcvP

RB2654_03414

RB2654_18563

Aminotransferase, classes I and II

Glycine dehydrogenase (aminomethyl-transferring) ; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein

0.862

RB2654_08302

RB2654_03414

RB2654_08302

RB2654_03414

Prephenate dehydrogenase

Aminotransferase, classes I and II

0.787

RB2654_08302

RB2654_10094

RB2654_08302

RB2654_10094

Prephenate dehydrogenase

Prephenate dehydratase

0.958

RB2654_08302

RB2654_21303

RB2654_08302

RB2654_21303

Prephenate dehydrogenase

Homoserine dehydrogenase

0.728

RB2654_08672

RB2654_03414

RB2654_08672

RB2654_03414

Aminomethyl transferase family protein

Aminotransferase, classes I and II

0.893

RB2654_08672

RB2654_18683

RB2654_08672

RB2654_18683

Aminomethyl transferase family protein

Bifunctional protein PutA ; Oxidizes proline to glutamate for use as a carbon and nitrogen source

0.985

RB2654_08672

RB2654_19533

RB2654_08672

RB2654_19533

Aminomethyl transferase family protein

Uncharacterized protein

0.856

RB2654_08672

RB2654_19638

RB2654_08672

RB2654_19638

Aminomethyl transferase family protein

Serine--glyoxylate transaminase, putative

0.884

RB2654_08672

RB2654_21303

RB2654_08672

RB2654_21303

Aminomethyl transferase family protein

Homoserine dehydrogenase

0.432

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: