Biological understanding of top genetic alterations across tumor types

Novel anti-cancer drug targeting

Reactivation of mutant p53

Studies related to p53 molecular mechanisms

Testing small molecules or biologics for cancer drug development

Type Strain

no

Biosafety Level

1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Comments

The Colon Cancer p53 Hotspot Mutation Cell Panel is comprised of 6 select cell lines derived from colon cancer that have been sequenced and validated by ATCC. The panel includes both WT p53 cell lines as well as cultures with p53 hotspot mutations at codons 175, 245, 248, or 273.

Product Format

frozen

Storage Conditions

LN vapor (less than -130°C) only

Permits

These permits may be required for shipping this product:

Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.