NiceLabel 2017 comes with pre-installed IronPython. IronPython is .NET variant of Python. It runs on .NET Framework and allows you to use .NET assemblies. Read more about it on IronPython site here. You can use the classes/functions from .NET.

You can also use "classic Python modules", such as "os" or "datetime", but in this case you have to install Python on the computer running NiceLabel. See KB article.