Making E. coli tasting flavors

Our project for this iGEM edition consists on designing a cellular biosensor. We use E. coli as cellular chassis, using a deficient EnvZ strain. We construct two different devices (a sensor and an actuator) that are assembled using OmpR-P as a standardized mediator. The sensor device contains a receptor protein and a synthetic two-component signal transduction pathway, both implemented through new parts in the Registry. The receptor protein has been designed computationally using a ribose binding protein as a scaffold and finding the necessary mutations to change its ligand affinity towards a vanillin molecule making E. Coli tasting flavors.

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Presentations at MIT

UPV-UV Valencia iGEM Program Sponsorship

iGEM is an initiative of the MIT iCampus program, which is funded by Microsoft Corp. The Valencia team has received a seed funding from the European Union and we are looking for sponsors. If you are willing to contribute with funding or resources, please contact Minerva Baguena