..The objectives of the new study were to replicate the test of paranoia and reasoning styles in a large general population sample and to assess the use of these reasoning styles in patients with persecutory delusions...

An early Phase II randomised controlled trial testing the effect on persecutory delusions of using CBT to reduce negative cognitions about the self: the potential benefits of enhancing self confidence

..Research has shown that paranoia may directly build on negative ideas about the self. Feeling inferior can lead to ideas of vulnerability. The clinical prediction is that decreasing negative self cognitions will reduce paranoia...

A pilot validation of a modified Illness Perceptions Questionnaire designed to predict response to cognitive therapy for psychosis

..Persecutory delusions are one of the key problems seen in psychotic conditions. The aim of the study was to assess for the first time the levels of psychological well-being specifically in patients with current persecutory delusions...

..The study provides the first demonstration that reducing height in a social situation increases the occurrence of paranoia. The findings indicate that negative social comparison is a cause of mistrust. ..

Paranoia and post-traumatic stress disorder in the months after a physical assault: a longitudinal study examining shared and differential predictors

..The clear next step is a pilot randomized controlled test. The clinical aim is to test whether CBT-I can reduce both insomnia and psychotic symptoms. The trial will inform decisions for a definitive large-scale evaluation...

The effects of reducing worry in patients with persecutory delusions: study protocol for a randomized controlled trial

..Therefore the aim of the trial is to test the clinical efficacy of a cognitive-behavioral intervention for worry for patients with persecutory delusions and determine how the worry treatment might reduce delusions...

Patients' beliefs about the causes, persistence and control of psychotic experiences predict take-up of effective cognitive behaviour therapy for psychosis

..We hypothesized that patients' initial ideas about the nature and extent of their problems would predict use of CBT. A match between patients' views of their problems and the principles underlying treatment would lead to better outcomes...

Insomnia, worry, anxiety and depression as predictors of the occurrence and persistence of paranoid thinking

..This is complicated by their frequent cooccurrence in schizophrenia. We hypothesized that persecutory and grandiose subtypes would differ significantly in their associations with psychological processes...

Laura FialkoDepartment of Psychology, Institute of Psychiatry, King s College London, University of London, UKSchizophr Res 100:53-9. 2008

..E., Green,L.W. and Levine,D.M., 1986. Concurrent and predictive validity of a self-reported measure of medication adherence. Medical Care. 24, 67-74] may be a preferable measure of medication adherence behaviour to the total scale score...

Neuropsychological functioning and jumping to conclusions in delusions

..It is concluded that nonclinical paranoid thoughts are most closely associated with emotional disturbances and anomalous experiences. Extreme reasoning bias may particularly contribute to the development of clinical phenomena...

..The study indicates that trauma may impact non-specifically on delusions via affect but that adverse events may work via a different route in the occurrence of hallucinatory experience. These ideas require tests in longitudinal designs...

..We conclude that the time budget measure can be used as an indicator of social functioning, with potential as a measure of therapeutic change. We are currently investigating its sensitivity in this context...

Discrepant illness perceptions, affect and expressed emotion in people with psychosis and their carers

..Required now is examination of these processes in psychosis groups where there is greater change in delusion conviction, as well as tests of the effects on delusions when these reasoning biases are specifically targeted...

Targeting reasoning biases in delusions: a pilot study of the Maudsley Review Training Programme for individuals with persistent, high conviction delusions

..A group with persecutory delusions is compared with a sample of non-clinical controls on a probabilistic reasoning task. Results suggest JTC is apparent in individuals with the persecutory sub-type of delusions...

Psychological investigation of the structure of paranoia in a non-clinical population

..Previous studies of paranoia have assessed only limited numbers of paranoid thoughts, and have not considered the experience from a multidimensional perspective or examined the relationship between different suspicious thoughts...

Persecutory ideation and insomnia: findings from the second British National Survey of Psychiatric Morbidity

..The aim of the present study was to examine the relationship between SC orienting response and hallucination proneness, delusional ideation, anxiety and self-focused attention in non-clinical individuals...

A randomised controlled trial of a worry intervention for individuals with persistent persecutory delusions

..The results of this study indicate that depression and related processes may contribute to the maintenance of paranoia. Trials are warranted of depression-related therapeutic techniques for people with persecutory delusions...

Insomnia and paranoia

Daniel FreemanDepartment of Psychology, Institute of Psychiatry, King s College London, United KingdomSchizophr Res 108:280-4. 2009

..It is plausible that sleep difficulties contribute to the development of persecutory ideation. The intriguing implication is that insomnia interventions for this group could have the added benefit of lessening paranoia...

..This is the first study to investigate the relationship between the level of state anxiety and the jumping to conclusions (JTC) reasoning bias in patients with first-episode psychosis using an experimental manipulation procedure...

Urbanicity, Persecutory Delusions, and Clinical Intervention: The Development of a Brief CBT Module for Helping Patients with Persecutory Delusions Enter Social Urban Environments

..We therefore developed a brief CBT intervention, based upon a formulation of the way urban environments cause stress and anxiety, to help patients with paranoid thoughts to feel less distressed when outside in busy streets...

..Our study investigated caregiver reports of aggressive acts committed by their relative with psychosis and their links to caregiver appraisals of the caregiving relationship and caregiver outcomes...

Misattribution of self-generated speech in relation to hallucinatory proneness and delusional ideation in healthy volunteers

..It is concluded that study needs to be made of the interaction between psychotic and neurotic processes in the development of delusions and hallucinations, and that neurotic and psychotic disorders may have common maintenance processes...

The use of immersive virtual reality (VR) to predict the occurrence 6 months later of paranoid thinking and posttraumatic stress symptoms assessed by self-report and interviewer methods: a study of individuals who have been physically assaulted

Daniel FreemanDepartment of Psychiatry, University of OxfordPsychol Assess 26:841-7. 2014

..In the future, VR environments may be used in the clinic to complement standard self-report and clinical interview methods...

Reasoning bias and belief conviction in obsessive-compulsive disorder and delusions: jumping to conclusions across disorders?

..This study investigated whether a reasoning bias ('jumping to conclusions'; JTC) found to be associated with higher levels of conviction in delusions is also associated with high-conviction beliefs in obsessive-compulsive disorder (OCD)...

Correlates of perceptual distortions in clinical and non-clinical populations using the Cardiff Anomalous Perceptions Scale (CAPS): associations with anxiety and depression and a re-validation using a representative population sample

Deirdre FinneganHealth Service Executive, Dublin, Ireland Institute of Psychiatry, Psychology and Neuroscience, King s College, London, United Kingdom The South London and Maudsley NHS Foundation Trust, London, United Kingdom University of Oxford, Oxford, England and Biomedical Research Centre at the South London and Maudsley NHS Foundation Trust, Institute of Psychiatry, King s College, London, United KingdomJ Nerv Ment Dis 202:829-32. 2014

..These findings offer further evidence of the potential deleterious impact of a negative interpersonal environment on patient symptoms in psychosis. ..