This is a lecture-based online course that includes the study of disruptions of normal physiology, processes that bring about these disruptions, and various ways in which the disruptions manifest themselves as symptoms, signs, physical findings, and laboratory findings. The course will explore the pathophysiology of genetic diseases, hypersensitivity and autoimmune diseases, infectious diseases, neoplasia, diseases due to physical and chemical agents, disturbances of fluid and electrolyte balance, and endocrine dysfunction.