NEW YORK — After spearheading an epic, 18-hour documentary on the Vietnam War, acclaimed filmmaker Ken Burns has turned to more personal subject matter — one that knows him very intimately, too.

Burns tackles the famed Mayo Clinic in his next film, exploring the history of the innovative Rochester, Minnesota-based hospital that has been dubbed “The Miracle in a Cornfield.” It has treated luminaries such as the Dalai Lama — and Burns.

The first time Burns went, he was immediately impressed by the level and detail of his medical care, like the patient was at the center, not the doctor. “I began to get curious about why this was so different from any other health care experience I’d had,” he said.

“The Mayo is just a quintessentially American story, just as baseball is a quintessentially American subject, as are the national parks, the Civil War,” Burns said. “And this was a story firing on all cylinders, at least as far as I felt. And it was a story that I don’t think had been fully understood.”

The documentary — directed by Burns, Erik Ewers and Christopher Loren Ewers — features the voices of Tom Hanks, Sam Waterston and Blythe Danner, as well as familiar touches: Peter Coyote narrates, there’s rousing music by Aaron Copeland and Scott Joplin, and evocative slow-scans of old photographs known as “the Ken Burns effect.”

The film is part of a documentary film empire Burns has on tap. Upcoming are works on the history of country music, Ernest Hemingway, Muhammad Ali, Benjamin Franklin and the American Revolution, as well as deep dives into crime and punishment in America and civil rights during President Lyndon Johnson.

“I’m plotted out to 2030 — God and funding willing,” he said with a laugh. “As much as I’d like to believe that I pick projects, in fact I think they pick me. And they pick me because they’re just quintessential American stories, whatever they might be.”

Burns has built a reputation for capturing sweeping historic moments with intimate details of peoples’ lives, tackling topics ranging from the Brooklyn Bridge to baseball, from Mark Twain to jazz. His films make the past come alive: Burns was once escorted out of an Alabama church by state troopers from people still upset by the Civil War’s outcome.

The Mayo film begins with the unusual collaboration by Dr. W.W. Mayo — “a doctor who worshipped Darwin,” Burns said — and a group of Franciscan nuns who began working with Mayo to help tornado victims in 1883.

The hospital adopted a salary-based model of teamwork — not based on ordering tests or a revolving door of patients — that is said to encourage innovation, time with patients and collaboration. In the film, Tom Brokaw and John McCain endorse its methods.

So does co-director Erik Ewers, who started the project not as a Mayo patient but ended up one. He had been suffering from intestinal problems for 20 years and had been given seven different diagnoses without finding relief. While he was filming the Mayo documentary, its doctors reached out.

Burns calls Mayo’s formula a “secret sauce” — one that also manages to have poor patients get free care — and hopes it can offer answers to America’s health care problems.

“We were making a film about the history the Mayo Clinic, but realized that in their story and in their example might be a way for us all to re-enter a conversation about the essential question: What do we owe each other in terms of taking care of each other?” he said.

Burns’ inimitable visual style is sometimes mocked, but the filmmaker isn’t in a rush to embrace flashy special effects, something he calls “all sizzle and no steak.” He admits to dragging his heels on embracing digital cameras and computer editing because he simply liked splicing film stock. But that doesn’t mean he’s inflexible — he used drones in the Mayo film.

“There’s a lot of sleek hares out there who are racing past the turtle that we are,” he said. “We make long films. And if you’re going to watch a long film, we have to make sure that we honor the attention you’re giving to us with an equal care in the crafting of it.”

The work is painstaking. For the documentary on country music, he estimates his team has poured over 100,000 photographs and scanned 60,000 of them — only to use less than 3,000. “I use the analogy of maple syrup: It takes 40 gallons of sap to make one gallon of maple syrup,” Burns said.

By delving into America’s past so much, Burns has learned a lot about human nature, but he dislikes the cliche that history repeats itself. He prefers to quote Mark Twain, who said “History doesn’t repeat itself but it often rhymes.”

His work has given him hard-won perspective. When people during the financial crisis in 2007 began evoking the Great Depression, Burns knew his history. He replied that if animals in the zoos were being shot for food, then it was an apt analogy.

“That’s what history can do. It’s a kind of an armor or at least a thermal layer that protects you from the chill of the present moment,” he said.

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