Our results demonstrated functional PAR-1 and PAR-2 expression in both HCEC and HCE-T. Activation of PAR-1 and PAR-2 led to upregulation of the proinflammatory cytokines IL-8, IL-6, IL-1-α and TNF-α in HCE-T. In human corneal sections PAR-1 and PAR-2 were expressed in the outer epithelial layer of the cornea. (arvojournals.org)

Using an inducible RNAi mouse model for downregulating SCRIB expression, we report an unexpected role for SCRIB as a positive regulator of cell proliferation during pregnancy associated mammary alveologenesis. (biologists.org)

In response to injury of the corneal epithelium, the remaining epithelial cells adhere to and migrate over a fibronectin matrix deposited at the wound site to cover the area of the defect. (arvojournals.org)

They maintain impressive growth rates of up to 4 μm/s for several millimeters or centimeters, depending on the species, without ever dividing and are one of the fastest elongating cells in nature. (plantcell.org)