A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.

Any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block.

A sedating histamine H1 antagonist with antimuscarinic activity, cyclizine is given by mouth as the hydrochloride salt, or intramuscularly or intravenously as the lactate, for the control of management of postoperative nausea and vomiting, and for the management of motion sickness.

2014-05-29

Cyclizine can be found in blood and urine samples of individuals who have taken this drug.