I know this is a dumb question, but....

I don't think it's a dumb question at all. I think my mom may have done some simple, large block quilts using the serger. I personally would be frightened of anything more complex but I'm not a serger expert.

I have! I tried it on the last quilt I made . I really like how secure it is and the raveling is almost non existant. HOWEVER... It is kind of tough to manage that exact 1/4 in seam. I guess with lots of practice it will come easier. I will certainly try it again.

I pieced the back of a quilt with the scraps from the front. The front was done the "regular"way, and the back on the serger. I couldn't tell the difference!!! I thought it went well, I have been serging along time, and didn't have an issue with seam allowances, it was scrappy, so if I made a mistake (did make 2 or 3) I just sliced off the seam allowance and went at it again. Now, granted, you can't do that when you are following an exact pattern!

My long-arm quilter did say it was noticeably thicker at the seam crossings, but she didn't have an issue with it. I made it in Oregon and shipped it to her in Alabama and she shipped it back...sort of a cross country journey!

If you are comfortable with the serger and you are ok if it eats a few pieces that you can discard, I say go for it...lots faster, neater, cleaner on the backside and no raveling.

My blocks usually have a lot of piecing so matching seams could be an issue. Wouldn't mind doing it on big block quilts though. I do serge the edges of quilts that I'm hand appliqueing but plan on removing that edge when the blocks are finished.

I've done it. For me, it's much harder to be accurate on the seam allowance. There is a lot of extra thread in the seam allowance, which makes the seam allowance bulkier. Also, you cannot press the seam allowances open if you need to somewhere. And, matching seams is considerably more difficult. I would do it again, but only for a denim or similar type quilt and a pattern with large pieces that did not require matching seams.

I did see a really cute one-layer denim quilt made by serger. The pieces were serged from the front with red wooly nylon thread, and then these seams were sewn down to lie flat. This was really cute, and it's been in the back of my mind to make that quilt someday.