A randomized study in oral immunotherapy for food allergy by Ministry of Health, Labour and Welfare in JAPAN

Acronym

A randomized study in oral immunotherapy (OIT) for food allergy

Scientific Title

A randomized study in oral immunotherapy for food allergy by Ministry of Health, Labour and Welfare in JAPAN

Scientific Title:Acronym

A randomized study in oral immunotherapy (OIT) for food allergy

Region

Japan

Condition

Condition

food allergy

Classification by specialty

Clinical immunology

Pediatrics

Classification by malignancy

Others

Genomic information

NO

Objectives

Narrative objectives1

The objectives of our study are to perform our rush oral immunotherapy (OIT) for children with severe food allergy, to evaluate the safety and efficacy of this method, and to analyze the mechanisms of desensitization and tolerance to food in this method.

Basic objectives2

Safety,Efficacy

Basic objectives -Others

Trial characteristics_1

Trial characteristics_2

Developmental phase

Assessment

Primary outcomes

A comparison of the dose response to double-blind, placebo-controlled food challenge (DBPCFC) before and after therapy between rush OIT group and elimination group. We will define the thresholds for clinically significant reactions in DBPCFC.