In The Big Bang Theory, Leonard and Sheldon are brilliant physicists - wizards in the laboratory, but socially inept outside of it. Enter beautiful, free-spirited neighbor Penny, who aims to teach them a thing or two about life. While Leonard spends his days looking for love, Sheldon is quite content video-chatting with platonic partner Amy Farrah Fowler or playing Secret Agent Laser Obstacle Chess with their ever-expanding universe of friends, including fellow scientists Raj and Howard, and Howard's new wife, the adorable micro-biologist, Bernadette.