BIOTOOLS SPOTLIGHT

KRISP BIOTOOLS INTRODUCTION:

KRISP host many of the tools that were developed in Bioafrica.net (Prof. Tulio de Oliveira old group website). The great majority of our tools are freely and openly accessible. In addition, we also provide a linux cluster so the tools can be used free of charge.

A new version of the phylogenetic bootstrap in which the presence of inferred branches in replications is measured using a gradual 'transfer' distance rather than the binary presence or absence index used in Felsenstein's original version. The resulting supports are higher and do not induce falsely supported branches.

This tool is designed to use phylogenetic methods in order to identify the HIV-1 subtype of a specific sequence. The sequence is analysed for recombination using bootscanning methods. The version 3 contains new CRFs (CRF01_AE to CRF47_BF).