The National Gallery of Umbria is one of the richest collections in Italy with works of international renown.

The impressive number and variety of artistic works housed in the museum range from paintings on wood, canvas and murals, to sculptures in wood and stone, to goldsmith's art and fabrics, which exemplify the artistic evolution in the territory between the 13th and 19th centuries.

This prestigious collection, displayed in chronological order, includes various masterpieces from the Middle Ages and Renaissance with works by Arnolfo di Cambio, Nicola and Giovanni Pisano, Duccio di Boninsegna, Gentile da Fabriano, Beato Angelico, Benozzo Gozzoli and Piero della Francesca. A considerable amount of space is dedicated to the Umbrian artists Benedetto Bonfigli, Bartolomeo Caporali, Fiorenzo di Lorenzo and especially to famous paintings by Perugino, Pintoricchio and their students and followers. Other sections, characterized by carefully designed display solutions, are dedicated to the masterpieces of the Sienese goldsmith's art, to the traditional "Perugian tablecloths" that are part of the Cagnotti Bellucci and Rocchi collections, to ceramic floor tiles produced from the 15th and 16th century and a never before seen collection of drawings, including a precious sanguine study by Federico Barocci. The museum's itinerary continues with an exhaustive collection of 17th-, 18th- and 19th-century paintings and sculptures created in Umbria by some of the most important artists of the time, such as Orazio Gentileschi, Valentin de Boulogne, Pietro da Cortona, Giovan Battista Salvi also known as Sassoferrato, Pietro Montanini, Corrado Giaquinto, Francesco Trevisani, Pierre Subleyras, Sebastiano Conca. The exhibition concludes with an original presentation of materials related to 19th-century Perugia topography and the precious Carattoli collection.