CBS and NBC are mostly in repeats tonight, so unless you're a CW reality fan, your best new network choices boil down to Fox and ABC. Luckily, that still leaves you with some terrific picks, starting with Fox's enjoyable adventure Human Target (8 ET/PT). Tonight, Chance (Mark Valley) is off to a remote Alaskan island to rescue a missing doctor from some evil mining company. Terminator Salvation's Moon Bloodgood guests.

You can go home again, but only if the right family's waiting. For Kelsey Grammer and Patricia Heaton, Hank and The Middle mark separate bids for the comedy comeback that eluded them together in Back to You. For ABC, tonight's debut marks the completion of an all-new lineup the network hopes recalls the glory days of its best family comedies.