Midfielders Kevin-Prince Boateng and Sulley Muntari have been suspended from Ghana's World Cup squad with immediate effect after they clashed with coach Kwesi Appiah and a team official.

The Ghana Football Association (GFA) confirmed the decisions ahead of the nation's Group G game against Portugal in Brasilia later on Friday morning (AEST).

Boateng was sanctioned following alleged "vulgar verbal insults targeted at coach Kwesi Appiah during the team's training session in Maceio this week".

Muntari's suspension was handed down "in the wake of his unprovoked physical attack on an executive committee member of the GFA and a management member of the Black Stars, Mr Moses Armah, on Tuesday 24th June, 2014 during a meeting".

Boateng had shown "no remorse for his actions" and both players had their World Cup accreditation withdrawn.

Ghana can still qualify for the knock-out stage if it beats Portugal and the result in the other Group G match between Germany and the United States goes its way.

Muntari was set to miss the Portugal fixture as he was suspended after earning a second booking of the tournament in last week's 2-2 draw with Germany.