With contributions from leading international academics across the biological sciences, this handbook takes a critical look at the key contemporary issues and debates in the field. The 31 chapters are divided into four parts:

Part I Determination of Substance Misuse

Part II PK and PD in Relation to Patterns of Use

Part III Detection and Treatment of Drug and Alcohol Use

Part IV Controversies and New Approaches

This Handbook is an excellent reference text for the growing number of academics, students, scientists and practitioners in the drug and alcohol studies community, and will be a vital resource to the allied professions involved in work-place drug testing, clinical toxicology, and forensic science.

Part I: Determination of Substance Misuse

Rohit Jaibhagwan Lodhi, David Rossolatos and Katherine Jean Aitchison

1. Genetics and genomics in addiction research

Kim Wolff

2. Basic Pharmacokinetics of Substance Misuse

Jason White & Andrew A. Somogyi

3. Future Directions: The role of pharmacogenomics

Part II: PK and PD in Relation to Patterns of Use

Matthew Goldin and E. Jane Marshall

4. Alcohol: Pharmacokinetics and Pharmacodynamics

Noorzurani Robson

5. Nicotine: The Pharmacokinetics of Nicotine and Cotinine

Verena Metz & Sandy Corner

6. Opioids: A Discussion of Pharmacokinetics and Pharmacodynamics in Those Who Misuse Drugs

31. Exploratory models to explain attention deficit hyperactivity disorder and its association with substance use

This new volume provides a very welcome and much needed compilation of key articles and reviews on various aspects of drug abuse. It includes a very useful introductory section outlining the basic principles in pharmacokinetics and pharmacogenomics and the subsequent chapters delve further into these principles for various classes of drugs of abuse. The information is clearly laid out and is complemented with a section on detection and treatment of drug and alcohol abuse. Recent controversies and debates on key aspects of drug abuse this handbook will stimulate the reader into considering further innovative aspects in this field. This handbook will prove to be a very reference textbook for toxicology students and a key addition to medical and health care science libraries.

Janet Mifsud

Professor of Clinical Pharmacology, University of Malta

At times of crisis, we observe an increase in the severity of drugs and alcohol related problems and a rise in gambling and internet addiction. The SAGE Handbook of Drug & Alcohol Studies Volume 2 comes at the right time todeepenour understanding of addiction aetiology and new forms that affect every area of personal and family life. The Handbook raises awareness of treatment options for successful recovery and for fighting stigma in today’s turbulent environment. This Handbook is a valuable tool for academics, researchers, students and professionals who strive to transform evidence based knowledge into successful practice.

Anna Tsiboukli

Head of KETHEA Department of Education, Hellenic Open University, Greece

Select a Purchasing Option

Order from:

SAGE Knowledge is the ultimate social sciences digital library for students, researchers, and faculty. Hosting more than 4,400 titles, it includes an expansive range of SAGE eBook and eReference content, including scholarly monographs, reference works, handbooks, series, professional development titles, and more.

The platform allows researchers to cross-search and seamlessly access a wide breadth of must-have SAGE book and reference content from one source.

SAGE Knowledge brings together high-quality content from across our imprints, including CQ Press and Corwin titles.