Fusion

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AMYB2

Beta-amylase (395 aa)

Predicted Functional Partners:

SBE2

Starch branching enzyme (788 aa)

0.900

SBE3

Starch branching enzyme (747 aa)

0.900

AGL1

Alpha glucosidase (1059 aa)

0.900

PHOB

Starch phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (1010 aa)

0.900

EDP02737

Alpha-amylase-like protein (404 aa)

0.900

AMYA1

Alpha-amylase (408 aa)

0.900

SBE1

Starch branching enzyme (690 aa)

0.900

AMYA2

Alpha-amylase (413 aa)

0.900

PHOA

Starch phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (872 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

AGL1

AMYA1

EDP03143

EDP02635

Alpha glucosidase

Alpha-amylase

0.592

AGL1

AMYA2

EDP03143

EDP00963

Alpha glucosidase

Alpha-amylase

0.592

AGL1

AMYB2

EDP03143

EDP08477

Alpha glucosidase

Beta-amylase

0.900

AGL1

DPE1

EDP03143

EDO97689

Alpha glucosidase

4-alpha-glucanotransferase

0.879

AGL1

EDP02737

EDP03143

EDP02737

Alpha glucosidase

Alpha-amylase-like protein

0.592

AMYA1

AGL1

EDP02635

EDP03143

Alpha-amylase

Alpha glucosidase

0.592

AMYA1

AMYA2

EDP02635

EDP00963

Alpha-amylase

Alpha-amylase

0.806

AMYA1

AMYB2

EDP02635

EDP08477

Alpha-amylase

Beta-amylase

0.900

AMYA1

DPE1

EDP02635

EDO97689

Alpha-amylase

4-alpha-glucanotransferase

0.703

AMYA1

EDP02737

EDP02635

EDP02737

Alpha-amylase

Alpha-amylase-like protein

0.812

AMYA1

PHOA

EDP02635

EDO98385

Alpha-amylase

Starch phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties

0.978

AMYA1

PHOB

EDP02635

EDP02951

Alpha-amylase

Starch phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties

0.979

AMYA1

SBE1

EDP02635

EDP01649

Alpha-amylase

Starch branching enzyme

0.973

AMYA1

SBE2

EDP02635

EDP08206

Alpha-amylase

Starch branching enzyme

0.972

AMYA1

SBE3

EDP02635

EDP05581

Alpha-amylase

Starch branching enzyme

0.973

AMYA2

AGL1

EDP00963

EDP03143

Alpha-amylase

Alpha glucosidase

0.592

AMYA2

AMYA1

EDP00963

EDP02635

Alpha-amylase

Alpha-amylase

0.806

AMYA2

AMYB2

EDP00963

EDP08477

Alpha-amylase

Beta-amylase

0.900

AMYA2

DPE1

EDP00963

EDO97689

Alpha-amylase

4-alpha-glucanotransferase

0.814

AMYA2

EDP02737

EDP00963

EDP02737

Alpha-amylase

Alpha-amylase-like protein

0.812

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Network Stats

Network Stats analysis is still ongoing, please wait ...

Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: