Lyophilized (freeze-dried) live vaccine for active
immunization of chicks
and adult birds against Newcastle disease.

Description

It is a live CEO virus vaccine derived
from embryonated SPF hen's eggs. It has been lyophilized
in vials and sealed under vacuum to preserve the stability.

Composition

Each dose contains not less than 106
EID50 Lasota strain ND virus.

Indications

This vaccine is recommended for vaccination
of chickens against Newcastle disease for both initial
vaccination and revaccination.

Vaccination schedule

This vaccine is recommended for use as
early as 2 weeks of age or older.

Revaccinate 3 to 6 weeks later.

It should be used as a revaccination after
the use of the B1 strain of Newcastle disease vaccine.

For replacement of pullets, a booster
vaccination should be given between 16 and 18 weeks of
age.

Administrations

Drinking water method :

Drinking water vaccination should be done during
the cooler part of the day.

Remove any disinfectant or sanitizer from the water
for 24 hours prior to and after vaccination.

Rinse all waterers with clean water prior to vaccination.

It is recommended that no water be given for at
least one hour before vaccination to allow birds to
get thirsty. This shall ensure that all birds get
an equal share of vaccine.

Dissolve vaccine in the drinking water as per schedule
mentioned in the pack insert, supplied with vaccine.

Provide ample drinking water space to all the bids.

Intraocular (eye-drop) method ( For 1000, 500
and
200 dose size) :

Combine the diluents with vaccine and mix well.

Place the dropper over the vial containing vaccine
solution.

Hold the chick with one eye turned up. Apply one
drop of vaccine in to open eye and hold until bird
swallows.

Intranasal method ( For
1000, 500 and 200 dose size) :

Combine the diluents with vaccine and mix well.

Place the dropper over the vial containing vaccine
solution.

Hold the chick with one eye turned up. Place one
finger over one nostril. Instil one drop of vaccine
into the open nostril and hold until bird breathes
in the drop.

Coarse Spray method :

Use only for revaccination.

The quantity of water for 1000 doses is 200ml from
the fourth week of life onwards.

Chlorine free or, preferably, distilled water should
be used.

Field spray application should be used only in
houses that can be tightly closed. Close all windows,
doors, ventilators, etc and turn off fan.

One dose of vaccine should be used for each bird.

Spray each 1000 doses of vaccine over 1000 birds.

Leave the house closed for at least 15 minutes
after spraying.

Care

When spraying live virus, some form of protection
against inhalation and contamination of the eyes must be worn.
Always use eye goggles.

Vaccination reaction

Respiratory symptoms may be observed following
the first vaccination depending upon the age and the level
of parental immunity in the chicks. While birds are going
through the reaction period, keep them comfortable by providing
adequate heat and good ventilation.

Precautions

Attention ! New Castle disease live virus
can cause inflammation of the eye and eyelids of humans.
Do not allow vaccine to come into contact with eyes.

Birds clinically ill or weakened by transport
should not be vaccinated.

This vaccine must not be used for spray
vaccination in the first three weeks of life (during this
time B1 strain may be used).