Notable events involving Ville de Quebec include:

28 Oct 1942HMCS Alberni (Lt. I.H. Bell, RCNVR) and HMCS Ville de Quebec (T/Lt.Cdr. A.R.E. Coleman, RCNR) together pick up 81 survivors from the British whale factory ship Sourabaya that was torpedoed and sunk the previous day in the North Atlantic in position 54°32'N, 31°02'W by German U-boat U-436

13 Jan 1943German U-boat U-224 was sunk in the western Mediterranean west of Algiers, in position 36°28'N, 00°49'E, by ramming and depth charges from the Canadian corvette HMCS Ville de Quebec (T/Lt.Cdr. A.R.E. Coleman, RCNR).