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genetic toxicity testing News

Effective from June 1, 2012, Annex XVII of the EU Directive known as REACH extends the list of restricted CMR substances (carcinogenic, mutagenic or repro-toxic) as categories 1A and 1B. Previously defined as categories 1 and 2 and now tagged categories 1A and 1B, the extended list of CMR substances in REACH Annex XVII entries 28-30 (appendices 1-6) was published five years ago in the ...

The October 21, 2011, Federal Register includes two test rules concerning high production volume (HPV) chemicals: a final test rule for certain chemicals from the third group, and a proposed test rule and proposed significant new use rule (SNUR) for the fourth group of chemicals. See 76 Fed. Reg. 65385 and 65580, respectively. The proposed "SNUR plus test rule" represents a ...

The October 21, 2011, Federal Register includes two test rules concerning high production volume (HPV) chemicals: a final test rule for certain chemicals from the third group, and a proposed test rule and proposed significant new use rule (SNUR) for the fourth group of chemicals. See 76 Fed. Reg. 65385 and 65580, respectively. The proposed "SNUR plus test rule" represents a novel approach for ...

The U.S. Environmental Protection Agency has awarded a $433,100 grant to the University of Chicago to investigate how allergic reactions to food are initiated. The research is expected to lead to improved methods to assess whether pesticides produced in genetically engineered plants can trigger food allergies, which impact more than 11 million Americans each year. The study is funded through ...

Applying a low voltage to polluted river sediment can boost microbes’ natural ability to degrade harmful polychlorinated biphenyl (PCB) contaminants, according to a new study. The approach could be a cost-effective, sustainable strategy to bioremediate polluted sites. PCBs are persistent contaminants as they remain for long periods in the environment, particularly in water, soil and ...

Bergeson & Campbell, P.C. (B&C) is pleased to announce that Jane S. Vergnes, Ph.D., DABT has joined our team as Senior Toxicologist for B&C and The Acta Group (Acta). Dr. Vergnes has demonstrated outstanding leadership and an agile, multi-disciplinary talent for problem-solving in her 25 years directing global product stewardship and toxicology departments for Ashland, Inc., ...

The U.S. Environmental Protection Agency (EPA) is recognizing Life Technologies in Austin, TX, for winning the 2013 Presidential Green Chemistry Challenge Award. Life Technologies developed a more efficient, less wasteful way to manufacture key chemicals used to perform genetic testing. “Companies, such as Life Technologies, demonstrate that using green chemicals can lower greenhouse has ...

EcoArray, Inc. announced the release of its 22,000-gene microarray in Fathead minnows designed for research and use in environmental toxicology. The array is available immediately. It is manufactured by Agilent Technologies using its custom oligonucleotide microarray platform. EcoArray’s President, John Rogers, said, “This array marks a step forward in bringing this important ...

The U.S. Environmental Protection Agency (EPA) is recognizing landmark green chemistry technologies developed by industrial pioneers and leading scientists that are contributing to the use of chemicals and products that are safer for people’s health and the environment. During the 18 years of the Presidential Green Chemistry Challenge program, EPA has received about 1500 nominations and ...

An innovative crowdsourced computational Challenge, called the NIEHS-NCATS-UNC DREAM Toxicogenetics Challenge, launches today. The objective of this Challenge is to obtain a greater understanding about how a person’s individual genetics can influence cytotoxic response to exposure to widely used chemicals. It is being led and organized by scientists from Sage Bionetworks, DREAM, the ...

Quantitative Polymerase Chain Reaction (qPCR) is a cutting edge molecular technology that analyzes for the genetic material called deoxyribonucleic acid (DNA) which is found in every cell. EMSL Analytical Laboratories has harnessed this powerful molecular testing technique to identify a host of microbial contaminants and pathogens, including Penicillium. Penicillium is a ubiquitous soil ...

Researchers at the Center of Excellence in Environmental Toxicology (CEET), Perelman School of Medicine at the University of Pennsylvania, have been awarded a $10 million grant from the National Institute for Environmental Health Sciences (NIEHS) over the next four years to study ...

Researchers at the University of Arizona College of Pharmacy have discovered that nonalcoholic steatohepatitis (NASH), an increasingly common but often undiagnosed liver disease, could have significant medical implications for people with type 2 diabetes. People develop NASH when early liver disease, characterized by too much ...

A ship repair company has been ordered to pay £24,300 in fines and costs for polluting Cornwall's famous Fal estuary with toxic paint sludge. The case was brought by the Environment Agency and Cornwall Council. On September 29, 2011 the Agency received a report of pollution in the estuary. On arrival an officer saw a large rusty-coloured plume in the harbour covering an area approximately ...

A genetically diverse mouse model is able to predict the range of response to chemical exposures that might be observed in human populations, researchers from the National Institutes of Health have found. Like humans, each Diversity Outbred mouse is genetically unique, and the extent of genetic variability among these mice is similar to the genetic variation seen among humans. Using these mice, ...

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