Results

In the phantom study, the difference between the measured and the true diameter of the neointimal formations was smaller on FIRST than FBP or AIDR 3D images. In the clinical study, the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of AIDR 3D were 58%, 88%, 83%, 67% and 73%, respectively. For AIDR 3D plus FIRST images they were 84%, 78%, 80%, 82% and 81%, respectively. The mean area under the curve was significantly higher on AIDR 3D plus FIRST than AIDR 3D images (0.82 vs 0.72; p < 0.01).

Conclusions

The model-based IR algorithm helped to improve diagnostic performance for the detection of neointimal formations after carotid artery stenting.

Key Points

• Neointimal formations can be visualised more accurately with model-based IR.

Notes

Funding

The authors state that this work has not received any funding.

Compliance with ethical standards

Guarantor

The scientific guarantor of this publication is Kazuo Awai.

Conflict of interest

Kazuo Awai, Professor of Hiroshima University, obtained a research grant from Canon Medical Systems. The other authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.

Statistics and biometry

One of the authors (F.T.) who has skill for statistics performed the statistical analyses.

Informed consent

Written informed consent was obtained from all subjects in this study.