In general, you want to clear as many people as possible, mathematically speaking. Despite the psych questions, the mathematics of the game is the most important aspect. I'd say the most important rule of the game is that if an employee votes for the boss, they cannot be fired. This means that if an employee who voted as a lemming was fired, that means that the person they voted for is not the boss. However, you need at least two people fired to follow this, because