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I regret buying this game full price. It's not bad, I like the mechanics, and in general I like roguelikes where skill is a bigger factor than RNG. But as others have said, the guns are just not that exciting. They can be very different from one another, but none of them (in the time I played before getting bored) really stands out. I was never excited to get a gun unless it was one I hadn't seen before, and that was just because I wanted to see what it did. Add that to the fact that you save your best guns for the boss anyway and it ends up being kind of a drag. Crypt of the Necrodancer is still the king for me.

Ugh, don't do it! That guide telling you to do certain things is micro-managing your game. Those things don't effect the outcome, just some dialog. I can't think of anything that's really missable*, you're just taking a different path. Like if you followed a Mass Effect walkthrough and it told you to only do paragon stuff. Just fly free.

*There are "missable" side quests, in that you have the freedom to skip them and go fight the final boss if you like. Those come towards the end of the game though, the first half/two-thirds are linear.

The game really starts at the higher difficulties, and it's all about getting rare drops. I'd recommend creating a Battle.net character rather than a single player one. You can still play by yourself by creating a private game, but you can also jump into some of the popular leveling runs to rush the development of your character ("trist runs" at about level 10, "tombs" at 20, then "Baal" runs until your XP stops rolling in). Those numbers might be wrong, haven't played in a while. But you might want to grind it out on your first character anyway.

If you're not going to be grinding/trading for rare items, the summoning necromancer (or "zookeeper") can be very powerful with minimal equipment. You don't need great items for anyone on normal or maybe even nightmare difficulty, though, so if you're just going to play through the campaign once, choose whatever build you want.

Look up cube recipes and runewords. That'll make more sense once you play a bit.

Can't speak for Red Faction but Space Marine is a damn good time. Satisfying mix of melee and gunplay. If you're not looking for melee then maybe avoid it, because when you're getting charged by a dozen orks you'll only be able to shoot for so long before you need to pull out the ol' chainsword.

Resident Evil 4 had some epic boss fights. It doesn't hold up as well now, but the lake monster was mind-blowing for me at the time.

Also Earthbound, that last fight will haunt you. But my favorite boss fights are the Guardian Diggers. There are five of them scattered throughout the dungeon, and for some reason before you fight each one, they claim to be the 3rd strongest of the group. They have identical stats too. It's exactly the type of silliness that makes that game great.

I actually got an email from GoG recommending your game based on my previous purchases (Commandos is what did it, I assume). Did you have to pay for that as advertising, or is it just something GoG does to increase sales? I can't remember getting an email like it before.

He still has the 45-yarder in the snow from the tuck rule game, plus the Super Bowl winner from the same year. I do think it's the second Super Bowl winner that made his "clutch" reputation though, funny how that works.