Mouse and Keyboard not working in game. (Also received an AFK penalty due to this)

This post is kind of me ranting a little because I am a tad bit, really angry right now, so bear with me.
4th ranked game ever, and 2nd game where a problem has occurred. LOL has worked flawlessly in all my 300 normals games, so either I am the unluckiest guy to play ranked, or someone at Riot hates me. I have an AFK penalty, and I'm pretty sure everyone in game reported me. Anyways, I had no control over my client, and I couldn't use my mouse, (Like instead of the league mouse it was the regular windows white mouse) or keyboard in-game. Literally no control. I have no idea what to do, but if anyone could help me that would be greeeaaaat.

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