You’ve probably seen those ubiquitous Zoloft commercials — where the little ovoid creature is incredibly sad and depressed. (There’s one above, in an example of a teensy Zoloft ad.) They’re actually incredibly affective commercials, I think, in part because they do a superb job at evoking the deep weariness that accompanies depression. Though it’s probably true that antidepressant medication is overprescribed right now in America, it is nonetheless a crucial way for depressed people to get help. Real, serious depression is nothing to scoff at.