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~ Project Fertility ~

Help with Injectables / PCOS

I have PCOS, like 60 follicles in each ovary. So I started my injections on Thursday (day 3) Gonal-F 75iu. My bloodwork was normal range estrogen 47. I went in for blood work yesterday (day 6) and my estrogen jumped to 351. They told me to cut my injectable dosage down to 37.5 and come in today for ultrasound. Went in today and there are NO dominant follicles! I am SO upset, so essentially all the little follicles are slightly growing (I guess thats what this means).

Does anyone really know what this means? Has anyone had this? Will just a few of the follicles grow?

Artlvr: I got no advice-I'm so sorry. When do you go back for another u/s? Did you try PMing Michelle?? Ugh. FX that the last two days have brought lots of growth and a dominant follicle (or two). Keep us posted....

Also, have you tried any boards on babycenter? Some of the women on there aren't the friendliest but they have a huge wealth of information and boards specifically geared toward this... Just promise that you won't leave us for them!

I'm sorry you're going through this, artlvr. It can't be easy. Yes, I do have experience with injectibles, though not Gonal-F. I did Follistim. But unfortunately, I don't have PCOS so I don't have any insight to give you about follicles not growing, etc. I know that there is another web site specifically for PCOS called www.soulcysters.com. You might be able to find good information on that site about what you are going through. I wish I had more knowledge to give you but I don't. :( I do hope they find the right combination of whatever it is you need to get those follicles growing!!

Thanks. I'm going to check that out. Went back to the doctor again today blood work and ultrasound. No follicle growth. I'm so upset. I'm trying not to be but it's hard. My RE said he wants to see what my blood work is today and either keep me on the gonal-f or he might switch me to a new injectable. 1 of my cousins had her baby the other is due next week. It's hard, we all started trying at the same time but they got pregnant right away and i still don't even have a follicle growing :( I'm just so upset!

Artlvr: Big hugs. This process just sucks. Keep us posted. I'm so glad that your RE is so proactive though. The monitoring, although grueling and emotional, really allows you guys to not waste time! When do you get to switch to a new drug? Which one is it? Big hugs and let us know how the bloodwork comes back.

Thanks so much! My estrogen went up so they kept me on te same dosage. Today was also a bust. It's getting pretty downright depressing every other day seeing nothing on the ultrasound. Hopefully Tuesday will be good news! How are you all doing?

Aw honey. I'm sorry. That just isn't fair. There is something out there that will work for you and this hell can one day all be forgotten. I wish that I had some really good advice but know that we're all here for you and staying tuned for tomorrow's update!

Thanks so much for asking! My RE office just called finally some good news! I'm so happy! There is 1 follicle they saw today 11.1mm! I am to continue on the injections same amount and I go in Thursday AM for ultrasound and blood work. FX this follicle keeps growing and growing!

I'm CD7 today so my third day of clomid. Go in Monday for an u/s and bloodwork. I remind my husband daily that he's so lucky that I don't get mean on the clomid--just horrendous hot flashes. Maybe, ladies, menopause will be a breeze after all of this.

so funny! Clomid side effects was only hot flashes for me but the injections are a whole different story. Not really too bad but my nipples are super super sensitive! (sorry if TMI), and I am really super bloated! and I have gained 4 pounds which doesn't seem like too much but on my 5 foot frame its a lot! But it is all worth it that the medicine is working and hopefully we will also see a BFP soon!

Tovaqt - I am excited to read your blog. I havn't told anyone but you ladies about my blog b/c I dont want any family or friends to read it. they have no idea we are even TTC let alone have fertility issues so I have found the blog a good way to talk things out. =) So what is your current update? New plan?

Mikesgirl - how excited are you for the insemination! So does that mean its going to be an IUI? FX for you! that your folly keeps growing!

As for me we had 2 Folly's on Saturday (17mm and 18.5mm) WHOA! So we were instructed to trigger sat night between 6-midnight and Timed Intercourse Sunday Night and Monday AM. So we triggered and had sex Sat night (why not), Sunday night and this morning. Tomorrow I start the prometrium, and now its the 2WW. I go in for bloodwork for a pregnancy test on Tuesday 10/25. I think I will test myself on Sunday 10/23 (which is our wedding anniversary so maybe that will be Good Luck!!!!) I really, really, really hope so!