Hi I have been depressesed for many years. Been on many diff drugs. Most seem to work well for a while (up to a year) befoe I seem to crash. Most recently I been on Duloxetine, but again I have crashed.

Doc is talking of using sodium valproate as a mood leveller. I only know this as a drug for epilepsy. How does it work as a mood leveller?

sodium valproate, or depakote, depakene...has been used for a long time, at least here in the states, as a "mood stabilizer." if you'll just do a search on depakote and mood stabilizer, you'll get so much info. i hope you'll have much more luck with this one. it's an "ol' timer." now they use all kinds of meds (anti-seizure) for other purposes as well, because with time, they find out more about how the brain works....i'm on topamax (an anti-seizure med) because it helps with other stuff (migraines), and i've had very good results with it. so, don't worry about it too much.

Hi I have been depressesed for many years. Been on many diff drugs. Most seem to work well for a while (up to a year) befoe I seem to crash. Most recently I been on Duloxetine, but again I have crashed.

Doc is talking of using sodium valproate as a mood leveller. I only know this as a drug for epilepsy. How does it work as a mood leveller?

Depakote is not used as much nowadays. The new drugs have less side effects. Lamictal is one. Most of the epilepsy drugs serve the purpose.