The ESP Timeline (one of the site's most popular features) has been
completely updated to allow the user to select (using the timeline controls
above each column) different topics for
the left and right sides of the display.

Foundation of the Royal Society, London, for the promotion of mathematical and physical science.

(no entry for this year)

1661

Robert Boyle publishes The Sceptical Chymist helping to transform alchemy into chemistry. Though an alchemist himself with his own cache of secret notebooks, Boyle begins writing up experiments for use by others.

(no entry for this year)

1662

(no entry for this year)

(no entry for this year)

1663

German physician Otto von Guericke pieces together bones from different species to make a fossil "unicorn."

Isaac Newton discovers that white light is composed of different colors.

1664

In his private museum in Rome, Virgilio Romano exhibits a Hippopotamus major canine tooth found in Pleistocene gravels along the Via Nomentana.

Thomas Willis publishes The Anatomy of the Brain and Nerves.

Isaac Newton discovers that white light is composed of different colors.

(no entry for this year)

1665

Robert Hooke observes cork under a microscope and uses the word cells to describe the tiny chambers that he sees. He publishes drawings of these cells, of fleas, and of other small creatures, in his book Micrographia.

Le Journal des Savants is first published in France, and Philosophical Transactions of the Royal Society is first published in England.

(no entry for this year)

1666

Gravity is discovered.

(no entry for this year)

1667

Niels Stensen (Steno) describes his dissection of the head of a giant white shark and correctly identifies shark teeth, still generally thought (despite arguments to the contrary from Rondelet and Colonna in the preceding century) to be serpent tongues.

Francesco Redi publishes Esperienze Intorno alla Generazione degli Insetti (Experiments on the Generation of Insects), which is regarded as his masterpiece and a milestone in the history of modern science. At the time, prevailing wisdom was that maggots arose spontaneously from rotting meat. Redi took six jars and divided them into two groups of three: In one experiment, in the first jar of each group, he put an unknown object; in the second, a dead fish; in the last, a raw chunk of veal. Redi covered the tops of the first group of jars with fine gauze so that only air could get into it. He left the other group open. After several days, he saw maggots appear on the objects in the open jars, on which flies had been able to land, but not in the gauze-covered jars. In the second experiment, meat was kept in three jars. One of the jars was uncovered, and two of the jars were covered, one with cork and the other one with gauze. Flies could only enter the uncovered jar, and in this, maggots appeared. In the jar that was covered with gauze, maggots appeared on the gauze but did not survive. Knowing full well the terrible fates of out-spoken thinkers such as Giordano Bruno and Galileo Galilei, Redi was careful to express his new views in a manner that would not contradict theological tradition of the Church; hence, his interpretations were always based on biblical passages, such as his famous adage: omne vivum ex vivo ("All life comes from life").

Jan Swammerdam dissects a caterpillar for Cosimo de Medici, demonstrating that the butterfly wings already exist inside the caterpillar's body. A year later, he will publish Historia Insectorum Generalis.

Robert Hooke presents a lecture to the Royal Society claiming that earthquakes, not the biblical flood, have caused fossils to be found on mountaintops and buried in stone.

(no entry for this year)

1669

Niels Stensen (Steno) publishes Forerunner, showing diagrammatic sections of the Tuscany area geology, making the important point that sediments are deposited in horizontal layers.

Brandt discovers phosphorus.

ESP Quick Facts

ESP Origins

In the early 1990's,
Robert Robbins
was a faculty member at Johns
Hopkins, where he directed the informatics core of GDB
— the human gene-mapping database of the international human
genome project. To share papers with colleagues around the world, he
set up a small paper-sharing section on his personal web page. This
small project evolved into The Electronic Scholarly
Publishing Project.

ESP Support

In 1995, Robbins became the VP/IT of the Fred Hutchinson Cancer Research
Center in Seattle, WA. Soon after arriving in Seattle, Robbins secured
funding, through the ELSI component of the US Human Genome Project, to
create the original ESP.ORG web site, with the formal goal of
providing free, world-wide access to the literature of classical genetics.

ESP Rationale

Although the methods of molecular biology can seem almost
magical to the uninitiated, the original
techniques of classical genetics are readily appreciated by one and
all: cross individuals that differ in some inherited trait, collect
all of the progeny, score their attributes, and propose mechanisms
to explain the patterns of inheritance observed.

ESP Goal

In reading the early works of classical genetics, one is drawn, almost
inexorably, into ever more complex models, until molecular explanations
begin to seem both necessary and natural. At that point, the tools
for understanding genome research are at hand. Assisting readers reach
this point was the original goal of The Electronic Scholarly Publishing
Project.

ESP Usage

Usage of the site grew rapidly and has remained high. Faculty began
to use the site for their assigned readings. Other on-line
publishers, ranging from The New York Times to Nature
referenced ESP materials in their own publications. Nobel laureates
(e.g., Joshua Lederberg) regularly used the
site and even wrote to suggest changes and improvements.

ESP Content

When the site began, no journals
were making their early content available in
digital format. As a result, ESP was obliged to digitize classic
literature before it could be made available. For many important
papers — such as
Mendel's original paper
or the
first genetic map
— ESP had to produce entirely new typeset versions of the works,
if they were to be available in a high-quality format.

ESP Help

Early support from the DOE component of the Human Genome Project was
critically important for getting the ESP project on a firm foundation.
Since that funding ended (nearly 20 years ago), the project has been
operated as a purely volunteer effort.
Anyone wishing to assist in these efforts should send an
email to Robbins.