Food additives: An overview of health implications and regulation and control in the United States Sharmeen Samuel, Kelly Brown, and Dilip R Patel

ORIGINAL RESEARCH Reliability and validity of the Chinese version of the psycho-educational profile (third edition) performance test Daniel TL Shek and Lu Yu

ORIGINAL RESEARCH Student development under a new general education program in Hong Kong: A 3-Year longitudinal assessment Daniel TL Shek, Lu Yu, and Xiaoqin Zhu

ORIGINAL RESEARCH Subjective outcome evaluation of the Tin Ka Ping P.A.T.H.S. Project in China: View of the students Daniel TL Shek, Tak Yan Lee, and Lawrence K Ma

ORIGINAL RESEARCH Evaluation of the Project P.A.T.H.S. in Mainland China: Views of the program implementers in senior high schools Daniel TL Shek, Florence KY Wu, and Mengtong Chen

ORIGINAL RESEARCH Evaluation of the training program of a positive youth development program: Tin Ka Ping P.A.T.H.S. Project in China Daniel TL Shek, Janet TY Leung, Mengtong Chen, and Chi Kin Chung

ORIGINAL RESEARCH Anti-doping knowledge of junior international racquetball athletes Timothy Baghurst

ORIGINAL RESEARCH Homeopathic potencies maintain their difference from each other and the aqueous ethanol control at different dilutions with water Atheni Konar, Tandra Sarkar, Nirmal C Sukul, Pallab Datta, Ashoke Sutradhar, and Anirban Sukul

Caregiver reports on the socio-economic and safety issues associated with Sakkiya treatment: A survey of a neglected area in Nigerian healthcare Kehinde K Kanmodi, Olanrewaju I Owoeye, and Godwin O Ndubuizu

Details

Proteins are important biomolecules that are vital for the cellular structure and function. They perform a vast array of functions within organisms, including the catalysis of metabolic reactions, DNA replication, response to stimuli, and transporting molecules from one location to another. The technological advances in the omics areas (e.g., genomics, transcriptomics, proteomics, metagenomics, etc.) have dramatically increased the rate of discovering new proteins. Some of them hold large opportunities for innovative research and the development of commercial products and applications. It is worth noting that the global protein ingredients market is poised to grow over the next decade to reach approximately 58.49 billion USD by 2022, with the protein therapeutics market valuing around USD 315.9 billion by 2025. Interestingly, about seventy monoclonal antibody products will be on the market by 2020 with a combined worldwide sales of about 125 billion USD.

The most significant parameter for the successful commercial exploitation of proteins rely on the development of an efficient and effective isolation and purification technology, known as protein downstream processing. Downstream processing refers to the technology that involves the isolation and production of purified products from natural sources such as animal tissues, plant tissues, microorganisms or fermentation broth. The most important element of this technology is the high purification process, most importantly of which is chromatography and in particular affinity chromatography.

The present book would definitely be an ideal source of scientific information to the advanced students, junior researchers, and scientists involved in cellular and molecular biology, biochemistry, microbiology, biotechnology and other related areas.

Chapter 3. Design, Synthesis and Application of a Synthetic Biomimetic Ligand for the Affinity Purification of Therapeutic Proteins
(Dimitris Platis and Nikolaos E. Labrou, Laboratory of Enzyme Technology, Department of Biotechnology, School of Food, Biotechnology and Development, Agricultural University of Athens, Athens, Greece)

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