After graduating from the Physics Department of the University of Athens, Ioannis Antoniou investigated different fascinating aspects of Complexity together with Ilya Prigogine (Nobel Prize 1977) at the Solvay Institutes, Brussels. Since 2001, he is teaching Information Theory, Chaos, Mathematical Modeling and Internet Traffic at the Mathematics Department of the Aristotle University of Thessaloniki.

Ioannis Antoniou has served as Deputy Director of the International Solvay Institutes of Physics and Chemistry in Brussels and Head of the Mathematics Department of the AUTH. Today, he is Director of the Graduate Studies of the Mathematics Department of the AUTH and Member of the Scientific Council of the International Joint Institute for Nuclear Research (JINR) in Dubna, Russia and 9 International Scientific Associations.

Ioannis Antoniou has directed 7 PhD Theses, 10 MSc Theses and 20 Graduation Theses. He has also been Member of the Examination Committee of 17 PhD theses and 12 M.Sc. Theses. He has coordinated 14 RTD Projects (EC:9, IST Luxembourg:4, INTAS:1), 4 International Research Collaborations and participated in 6 RTD Projects (EC:2, NATO:2, INTAS:2). He has organized 23 Conferences and participated in 175 Conferences. He is the author of 133 papers in journals, 41 papers in conference proceedings, 18 research reports, co-editor of 11 books, 5 translations, 10 letters, 2 patents and 11 articles/interviews for the general public. Ioannis Antoniou has served as Referee in 14 Journals, Member of the Editorial Board of 9 Journals, Reviewer of RTD Projects (EC, NSF, DOE, Guggenheim, NATO, UNESCO).

Ioannis Antoniou is Professor Honoris Causa of Lomonosov Moscow State University and St. Petersburg State University and Member of the European Academy of Arts, Sciences and Humanities. He was awarded the Kapitza Medal of Russian Academy, the De Donder Prize from the Royal Academy of Belgium (1991-1993) and the Prigogine Price (2008).