LEXINGTON, Mass., April 17 /PRNewswire/ -- Tepha, Inc., a developer of
medical devices derived from a new class of polymers, announced today that
two of its corporate partners, Aesculap and Tornier, are conducting initial
clinical evaluations of the Company's new TephaFLEX(R) suture products.
These clinical evaluations, conducted in both the United States and Europe,
represent the first human usage of medical devices derived from Tepha's new
class of resorbable polymers called polyhydroxyalkanoates ("PHA's"). The
Tepha PHA polymer family is a product of the Company's patented recombinant
DNA technology which allows the engineering of resorbable medical devices
with mechanical and biologic properties that are matched to specific tissue
repair and replacement applications. TephaFLEX(R) monofilament suture is up
to 30% stronger, more flexible, and has longer strength retention than
currently marketed resorbable sutures.

Dr. Simon Williams, President and CEO of Tepha, commented, "The first
human usage of a medical device based on our proprietary polymer technology
is an important milestone in Tepha's history. We are grateful for the
support of such capable and committed partners as Aesculap and Tornier, and
we look forward to these collaborations progressing to the successful
commercialization of TephaFLEX(R) suture products."

Aesculap AG, a Tepha corporate partner since 2004, currently is
conducting a European trial evaluating suture products based on
TephaFLEX(R) fiber in 150 patients undergoing abdominal wall repair
procedures. The results of this trial will be submitted to European
regulatory authorities to support Aesculap's application for CE Mark
approval. Based in Germany, Aesculap is a division of B. Braun Melsungen
AG, focused on products for core processes in operative medicine.
Aesculap's product range includes sutures, implants for orthopedic and
spinal surgery, surgical instruments, endoscopes, surgical motor systems,
container and storage systems, and vascular therapy products.

Tornier, a Tepha corporate partner since 2007, recently supported the
clinical evaluation of the TephaFLEX(R) Absorbable Suture by several
leading orthopedic surgeons in the United States. The TephaFLEX(R)
Absorbable Suture, FDA 510(k) cleared in February 2007, was utilized in a
range of orthopedic soft tissue repair procedures. Tornier, based in Edina,
Minnesota, is a leader in the extremity orthopedics market and is
collaborating with Tepha on several products for orthopedic soft tissue
repair.

About Tepha, Inc.

Tepha, Inc, is a developer of medical devices derived from a new class
of resorbable polymers that have been engineered utilizing recombinant DNA
technology. The unique biologic and mechanical properties of the Tepha PHA
polymers has been recognized by an expanding list of corporate partners
that now includes Aesculap AG, ENTrigue Surgical, HemCon Medical
Technologies, LifeCell Corporation (Nasdaq: LIFC), NMT Medical (Nasdaq:
NMTI), and Tornier, Inc. Tepha received its first FDA 510(k) clearance for
its TephaFLEX(R) Absorbable Suture in February, 2007 and the Company and
its partners have now received five 510(k)'s covering a range of medical
devices including sutures, meshes, and films.

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