There were no signs of hypersensitivity. A convincing case of alprazolam induced liver injury characterized by a mild cholestatic hepatitis arising 2 to 3 weeks after starting the medication and resolving rapidly with stopping.

Xanax Disease Interactions

Data sources include Micromedex (updated June 2nd, 2017), Cerner Multum (updated June 5th, 2017), Wolters Kluwer (updated June 6th, 2017) and others. provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. To view content sources and attributions, please refer to our editorial policy. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

Availability Rx Prescription only.

Severe Potential Hazard, High plausibility.

Applies to: Psychosis, Depression.

Status epilepticus may occur in patients with a history of seizures withdrawn rapidly from benzodiazepine therapy.

Xanax and Alcohol

Black outs are literally temporary memory lapses caused by impairment to the brain. Blacking out is more serious than you may think. It may seem funny to a partier to not remember pieces of the night before, but in reality that person is giving his or herself brain damage slowly. Other short-term side effects caused by alcohol abuse include blacking out, getting a hangover, weight gain, high blood pressure and reduced sexual performance. The more dangerous/less desirable short-term effects of alcohol include slurred speech, drowsiness, emotional instability, disrupted sleep, lowered body temperature, and in excessive cases can include nausea, vomiting, loss of control over the excretory system, a blackout, a coma, and even death.

Continued use of Xanax over many years, for longtime addicts, can cause dementia, amnesia, respiratory depression, delirium, severe depression, violence, and even psychosis.

Xanax and Alcohol

Xanax can cause abnormal amounts of liver enzymes, which are proteins used by cells. This can permanently damage the liver. Many more forms of long-term damage are caused from the body becoming used to the effects of Xanax.

The effects are worse due to the additive effect. The side-effects from an Alcoho combo (not previously listed) are anoxic brain damage, liver cancer, cardiomyopathy, arrhythmia, stroke, mouth/throat cancer, breast cancer, and pancreatitis. Not that the side effects of Alcohol and Xanax on their own aren’t bad, but a list of potential side effects from combining Xanax and Alcohol is worse.

It can also cause nausea, stomach-bleeding, double vision, temporary amnesia, lack of focus, and muscle tremors in the short-term.

Using Alcohol with Alprazolam (Xanax) Signs and Effects

Alprazolam, more commonly known by the brand name Xanax, is an anti-anxiety and panic disorder medication. Alprazolam is part of a class of drug called benzodiazepines, which have the potential to be addictive.

About 1/4 of people prescribed benzodiazepines take them long-term (SAMHSA, 2011). Approximay 95% of patients entering treatment for benzodiazepine addiction also suffer from a co-occurring substance addiction (Gage et al., 2014). At least 16 million people had an alcohol use disorder in 2013 (CDC, 2015). Alcohol and Alprazolam Abuse question 5.