Could Asthma Medications Be A Treatment for Parkinson’s Disease?

Could Asthma Medications Be A Treatment for Parkinson’s Disease?

The very same medicine that is commonly prescribed to treat asthma might also act as a means to prevent Parkinson’s disease. This is what a new chronic disease treatment study suggests.

Researchers from the University of Bergen (Norway) say that the study suggests medicines that treat asthma (and also, apparently, high blood pressure) might have some effect on a person’s risk of getting Parkinson’s disease. More specifically, though, the research team says that asthma medication could actually cut Parkinson’s risk by roughly 50 percent. On the other hand, taking certain blood pressure medications might double the risk.

University of Bergen professor, Trond Riise, notes, “Our analysis of data from the whole Norwegian population has been decisive for the conclusion in this study. Our discoveries may be the start of a totally new possible treatment for this serious disease. We expect that clinical studies will follow these discoveries.”

In the study, researchers looked at data from more than 100 million Norwegian prescriptions filled over the last 11 years. Sure enough, they found that Parkinson’s disease was associated with both asthma prescriptions and hypertension prescriptions. And this is what gave the researchers an opportunity to investigate the link(s).

Now, the researchers also advise that this is a preliminary discovery. Indeed, they still need to do a lot more research on the link between these medications and Parkinson’s disease before they can start making medication suggestions.

What we do know, for now, is that asthma (and other lung condition) drugs contain compounds called beta-2 adrenergic agonists. Essentially, these compounds dilate the air ways. You can typically find these in drugs like albuterol (ProAir, Ventolin) and metaproterenol.

Commenting on the research, Brigham and Women’s Hospital neurologist and lead author Dr. Clemens Scherzer comments, “We think this is an exciting potential pathway to developing new treatments for Parkinson’s.” He also makes sure to caution, again, that this by no means is any time to start prescribing asthma medications as a Parkinson’s treatment.

Parkinson’s disease remains quite mysterious in the medical community. While we can identify the symptoms—shivering, stiffening of the arms and legs, poor coordination, all caused by destruction of brain cells—we still do not know the cause.

Potentially Dangerous Asian Tick Infested 8 States

Entomologists issued a new warning about the rapid spread of a particularly aggressive tick this season. Initially discovered in New Jersey, the Long-horned tick has now been found in eight states, including North Carolina and as far west as Arkansas.

Scientists report the tick can infest a host rapidly, with femalesproducing thousands of tick eggs at a time asexually. Each tick will gorge itself on the host’s blood until the tick can barely move. The pest has been known to draw enough blood from animals to induce anemia.

Also known as the East Asian Tick, or its biological name of Haemaphysalislongicornis, the newcomer to America is not easily identified without a microscope. Its distinctive “long horns” are not visible to the naked eye.

Initially, authorities thought the first of the ticks werediscovered last summeron a sheep in New Jersey. When the sheep’s owner brought a sample of what she pulled off her pet, Department of Health officials discovered the sheep and her entire paddock were infested with the creatures.

Since the sheep had not traveled anywhere in years, officials are at a loss to explain how the tick came to be in New Jersey. The Health Department later confirmed that a tick discovered on a dog in another New Jersey county in 2013 was also a long-horned tick.

Despite an aggressive attempt to kill the ticks, which included sheering the sheep and removing vegetation from the paddock, additional long-horn ticks were discovered this spring. That prompted a state alert that the ticks had “successfully wintered”, surviving freezes, snow, and rain.

During routine tick monitoring, which can as simple as dragging sheets through meadows, more of the East Asian menace were discovered in Virginia, West Virginia, and North Carolina by June. Over the summer, New York, Arkansas, Maryland, and Pennsylvania also reported cases.

The good news about East Asian Ticks

So far, none of the long-horned ticks found in the United States carried any diseases. That is not to say they are completely harmless to your animals, which can be overwhelmed by the sheer number of ticks if not recognized quickly.

The exotic pests are controlled by the most common repellents and behaviors we use against out domestic ticks. Deet is the most effective chemical repellent.

Officials also remind everyone to use long sleeves, pants, and socks while walking through high grass and be sure to check yourself and children for ticks when you get home.

The bad news about East Asian Ticks

Even though no disease-carrying ticks have been found in the United States yet, these ticks are known to cause serious health issues in their native country.

Severe Fever with Thrombocytopenic Anemia (SFTA) and Japanese Spotted Fever are among several diseases spread by the tick in other countries. Both can be fatal if not treated promptly. It is not yet known if the East Asian tick can spread Lyme Disease.

Scientists warn dairy farmers to check livestock. The ticks can spread an animal disease called theileriosis, which causes decreased milk production in cows and potentially fatal blood loss in calves.

What you need to do about long-horned ticks

Pet owners and farmers should regularly check their animals for ticks. Learn how to safely remove them from animals (or yourself).

Every local health department accepts ticks for identification and disease testing. Place the tick in a plastic bag with a small stick, leaf, or a piece of cotton (to keep it from getting crushed) and deliver it to the health department.

If you find a tick on yourself, remove it and clean the area thoroughly with soap and water. Be attentive to any signs or symptoms of illness and be sure to tell your doctor about the tick. In most cases, even the most serious ailments can be headed off by prompt treatment.

Moderate Drinking Can Help You Live A Little Longer?

And now some good news for casual drinkers:a new study claims that moderate consumption of wine and beer (and coffee) can actually increase lifespan.Working with a group of 1,700 subjects older than 80, since 2003, a research team out of University of California-Irvine says that people who drank moderate amounts of alcohol and/or coffee lived longer than those who abstained [from either or both].They also say they learned that those who live longer tend to be on the heavier side in their 70s than those who or on the underweight side.

Now, to be sure, the researchers are still trying to understand these resultsLead study researcher Dr. Claudia Kawas notes, “I have no explanation for it, but I do firmly believe that modest drinking improves longevity,” in a presentation at the American Association for the Advancement of Science conference.

She explains that the “The 90+ Study” has been tracking the health of these study subjects for roughly the last 15 years, adding, “Those who consumed approximately two glasses of beer or wine a day were 18 percent less likely to experience premature death.”

On the other hand—or, concurrently, perhaps—the researchers also found that those who consumed about two cups of coffee per day also decreased their risk for early death by 10 percent.However, it is also very important to note that daily activity was also a factor that reduced premature death. This assuaged the researchers to suggest that keeping a healthy weight (not underweight) and engaging in regular physical activity and eating healthy can not only stave off premature death but also chronic disease.

At the end of the day, Dr. Kawas reminds that they still do not really know why modest drinking—and a few extra pounds—seems to help people live a little longer, but this study soundly speaks for such a case.

Other interesting facts they found include:

Those who are slightly overweight—not obese—reduced their odds of premature death by 3 percent

As few as 15 minutes and as many as 45 minutes of daily physical activity could reduce premature death by up to 11 percent

Spending about 2 hours a day on a hobby could decrease risk for early death by as much as 21 percent

New 5-Cluster Classification for Diabetes

For a long time, the medical industry has associated diabetes into two categories.Type 1 diabetes, of course, is genetic; you are born with it. Type 2 diabetes is also known as Adult-Onset diabetes and is a lifestyle disease that evolves over time, associated with the body’s eventual resistance to insulin.

More recent studies, however, now suggest that there are actually 5 different types of diabetes. Or, rather, Scandinavian researchers argue that the two types could further divide into five total clusters with different physiological and genetic distinctions.

From data on roughly 15,000 patients, taken from five cohorts in Finland and Sweden, the researchers used six standard measurements to identify these five clusters.Essentially there are two mild forms and three severe forms.

The first form is basically Type 1 diabetes, attributed to a genetic predisposition. The remaining four dissect Type 2 diabetes into different degrees of severity.

Cluster 1:Severe Autoimmune Diabetes (SAID)

Cluster 2:Severe Insulin-Deficient Diabetes (SIDD)

Cluster 3:Severe Insulin-Resistant Diabetes (SIRD)

Cluster 4:Mild Obesity-Related Diabetes (MOD)

Cluster 5:Mild Age-Related Diabetes (MARD)

According to consultant and Imperial College London clinical scientist Dr. Victoria Salem, most specialists have long pursued that are 2-tier diabetes definitions is “not a terribly accurate classification system.” She goes on to say, “There is still a massively unknown quantity – it may well be that worldwide there are 500 subgroups depending on genetic and local environment effects,” adding that this is definitely going to improve the way we think about diabetes as a disease.

Lead study author Leif Groop, MD, PhD, of the Lund University Diabetes Center in Malmö, Sweden, and Folkhalsan Research Centre, Helsinki, Finland, comments,

“Existing treatment guidelines are limited by the fact they respond to poor metabolic control when it has developed, but do not have the means to predict which patients will need intensified treatment.”

Finally, McGill University’s Rob Sladek, MD, explains in an accompanying editorial, “This study moves us towards a more clinically useful diagnosis, and represents an important step towards precision medicine in diabetes. Nevertheless, the finding that simple parameters assessed at the time of diagnosis could reliably stratify patients with diabetes according to prognosis is compelling and poses the challenge of development of methods to predict outcomes of patients with type 2 diabetes that are more generalizable and comprehensive.”