Aaron Bailey from Thermo Fisher Scientific's Life Sciences Mass Spectrometry, Biopharma Marketing group introduces us to the new Q Exactive HF for Biopharma at ASMS 2016. With its high-mass range mode it can do peptide mapping (bottom-up), as well as top- and middle-down (thanks to HRAM Orbitrap capability) and a significantly improved intact protein analysis capability for biopharma analysis.