The wide receiver left Sunday's 36-31 win in the fourth quarter, having gone down on the field in pain after running a route that did not appear to involve any contact.

McVay said afterwards that the injury was "not good", with Los Angeles listing a knee issue. Kupp missed two games in October with an injury to his left knee, which he appeared to be holding as he went down.

Kupp is now expected to undergo surgery this week to repair the ligament.