Glycogen storage disease is a glycogen metabolism disorder caused by deficiency of the glycogen debranching enzymes (AGL) and this results in accumulation of glycogen in the liver and other organs. Glycogn Storge Disease Type llla (GSDlla) affects Curly Coated Retriever.

Clinical Signs

Affected dogs show less symptoms in early life but older dogs exhibit exercise intolerance, lethargy, episodic hypoglycemia and prolonged recovery from exercise and collapse.