“Big Bang” will start the season at 8 ET/PT on Monday nights. It will be followed by “Mom,” in hopes of giving the second-year show a boost. When “Big Bang” moves back to Thursdays in late October, “2 Broke Girls” will take over the 8 p.m. Monday spot.

The other new shows on the fall schedule are “Scorpion,” a drama about “eccentric genius Walter O’Brien (Elyes Gabel) and his team of brilliant misfits who comprise the last line of defense against complex, high-tech threats of the modern age”; “Stalker,” a crime drama from Kevin Williamson starring Dylan McDermott and Maggie Q; “The McCarthys,” a comedy about a sports-mad Boston family; and “Madam Secretary,” starring Tea Leoni as the secretary of state.

“Scorpion” will air at 9 p.m. Mondays, with “NCIS: LA” following at 10. “Stalker” takes over “CSI’s” old slot at 10 p.m. Wednesdays. “The McCarthys” gets the post-“Two and a Half Men” spot on Thursday nights, and “Madam Secretary” will go at 8 p.m. Sundays, between “60 Minutes” and “The Good Wife.”

Veteran shows “The Mentalist,”“Mike & Molly” and “Undercover Boss” will be held for later in the season. Spinoff “CSI: Cyber,” the Vince Gilligan-David Shore drama “Battle Creek” and a remake of “The Odd Couple” starring Matthew Perry and Thomas Lennon will also come later in the season.