Danny Green scored 16 points and Tim Duncan had 12 points and 16 rebounds for the NBA-leading Spurs, who haven't lost since Feb. 21 while winning 14 of 15.

With their seventh straight victory over the Lakers dating to last season's playoffs, the Spurs opened a 1½-game lead over Indiana for the league's best record. San Antonio leads Oklahoma City by two games atop the Western Conference.

San Antonio held off a decent challenge from the miserable Lakers with strong shooting down the stretch and 14 second-half points from Leonard. Green and Manu Ginobili hit three 3-pointers apiece for the Spurs, who opened a three-game California road trip by calmly matching their longest winning streak of the season.

Kent Bazemore scored 13 points and hit three 3-pointers for the Lakers, who hadn't played since their 34-point loss at San Antonio five days earlier. That win was the biggest in this long-standing rivalry for the Spurs, who have followed up last spring's four-game playoff sweep of Los Angeles with three straight wins this season.

Kobe Bryant has played against the Spurs just four times in the clubs' last 12 meetings.

Green hit five of the Spurs' 13 3-pointers in last week's blowout, but the Lakers largely kept up with powerful San Antonio in the rematch. Los Angeles led for stretches of the third quarter before San Antonio scored 18 points in roughly 3½ minutes with big baskets from Parker and Leonard.

San Antonio matched its largest lead of the night at 108-97 on Duncan's jumper with 6:03 left. Marco Belinelli and Parker contributed big shots down the stretch as the Spurs pulled away.

The Lakers yielded 100 points for the 12th consecutive game and gave up 110 for the seventh straight game. Los Angeles is the Western Conference's worst defensive team.

Robert Sacre had seven points and a career-high 11 rebounds for Los Angeles.

NOTES: NBA Commissioner Adam Silver, Baron Davis and new Oakland Raiders left tackle Donald Penn attended the game. ... The Lakers will be without G Jordan Farmar for at least two weeks while he recovers from a moderate groin strain. Los Angeles still is without G Nick Young (sore left knee), F Jordan Hill (sore right knee) and G Steve Nash. ... The Spurs, who have no currently injured players, have missed 83 games due to injury this season. The Lakers have missed 260. ... San Antonio will attempt to sweep the clubs' season series when they meet in Texas on April 16 in both teams' regular-season finale.