Example sentences for:
dermenkephalin

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Fifteen minutes after dermenkephalin administration, the ultrastructural analysis showed a pattern of labelling quite different from that observed in the control rats in lamina I. At the level of labelling, the plasma membrane was noticeably invaginated (Fig.

Our findings demonstrate that dermenkephalin, after in vivo administration, can induce an internalization of the δ-opioid receptor at the level of the spinal cord.

We examined the effect of dermenkephalin, a specific δ-opioid agonist, in order to mimic the effect of a strong and constant activation by an agonist, on the distribution of the δ-opioid receptors, in the dorsal horn of the rat spinal cord.

Three groups of four animals were used: two groups received dermenkephalin and one control group received 0.9% NaCl.

The two experimental groups received intrathecally 10 μl of a mixture containing 10 μM of thiorphan and 20 μM of kelatorphan (to delay the degradation of the peptide ligand) and 10 μM of dermenkephalin (Tyr-D-Met-Phe-His-Leu-Met-Asp-NH 2 , Sigma, a selective δ agonist ( 14, 34)), in 0.9% NaCl.