"After 13 years on NCIS, Michael Weatherly is leaving the show at the end of this season," the network said in a statement. "He is a valued part of the CBS family, and the immense charm and talent he brings to the screen as 'Very' Special Agent Tony DiNozzo has helped make NCIS what it is today — the No. 1 drama in the world."

"We thank Michael for all of his contributions to this successful franchise and look forward to continuing to develop projects with him as part of our ongoing development deal," the statement continued.

Weatherly addressed the news on Twitter, expressing his appreciation for his colleagues and the show's viewers.

"I will miss the amazing crew & cast, who are like family to me, & to the fans all over the world — THANK YOU, it’s been a fantastic ride!" he tweeted.

This comes three days after TMZ reported that Weatherly pled no contest to a DUI charge stemming from a November arrest.

In an interview with Vulture Hound published Monday, January 4, NCIS actor David McCallum (Ducky) said that DiNozzo's departure at the end of the season has long been in the works. Weatherly leaves McCallum, Mark Harmon (Gibbs) and Pauley Perrette (Abby) as the series' only remaining original cast members.