Summariesfor MTHFD1L gene

The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF

is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from

homocysteine. Several transcript variants encoding different isoforms have been found for this gene.(provided by

RefSeq, Jun 2011)

GeneCards Summary for MTHFD1L Gene:

MTHFD1L (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like) is a protein-coding gene. GO annotations related to this gene include methenyltetrahydrofolate cyclohydrolase activity and protein homodimerization activity. An important paralog of this gene is MTHFD2.