Background:improved survival due to the
availability of several treatment optiona, cost-effectiveness
and health-related quality of life (HRQoL) issues have
gained increasing attention in colorectal cancer (CRC).

Aim: In the present study, we aimed to evaluate quality of life, level of anxiety and depression before and after a 6-month follow up period in chemotherapy receiving patients with CRC.

Methods:The study was conducted in
50 patients with colon or rectal
cancer. All patients were informed and educated about their disease and
treatment before getting the treatment and
were followed for 6 months, during which they received chemotherapy. A
“Questionnaire Form” to collect patient demographic characteristics; the “EORTC QLQ-C30 Scale” and “EQ-5D
Scale” to evaluate patient’s quality of life;
and the “Hospital Anxiety and Depression Scale”
(HAD) to evaluate the level of anxiety and depression
status of
patients, were used as data collecting tools.

Results: Quality of life scores in all functional fields were high in the sixth
course when compared to the first according to EORTC QLQ-C30 Scale, reaching to
statistically significant level in emotional
function score compared to the initial ones (P<0.05).
Moreover quality of life score
measured in the sixth month with EQ-5D
was statistically significantly higher than the initial.

Conclusions:these data, shows that with proper patient management, quality of life score, and the anxiety and depression levels improve during the course of treatment.