Advances in Phytochrome Engineering

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CBST researchers are continuing to improve their understanding of the photochemistry of plant phytochromes, and are thus able to develop smaller, single-domain phytofluors. Such small fluorescent proteins are critical for allowing nondisruptive labeling of living cells.

Roger Tsien, a world expert and pioneer in the field of fluorescent proteins, acknowledged that these phytofluors are the only photoswitchable molecules to work in the far-arc regime, and will play an essential role in ultra-high resolution imaging of tissue in the future.