News

Clotrimazole Mechanism of Action

Author:Kathy

Source:www.oceanchinachem.com

Release on :2016-05-24

Clotrimazole by interfering with the activity of
cytochrome P - 450, thus inhibiting fungi ergosterol cholesterol biosynthesis,
such as damage fungi and change the permeability of cell membrane, so that the
important material leakage in the cell; Inhibits fungal triglycerides and
phospholipids biosynthesis; Also inhibits oxidase and peroxidase activity,
leading to hydrogen peroxide in the cell accumulation cells the microstructure
degeneration and necrosis. Skin candidiasis caused by candida albicans and
vulvovaginitis, from red, tinea versicolor bacterium, MAO MAO versicolor
bacterium flocculent skin tinea caused by bacteria and dog microspore bacteria
ringworm of the body, tinea, tinea and chaff marla fungus of tinea versicolor
caused by color, also can be used in the treatment of paronychia, ringworm,
tinea capitis.

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