nadrolone

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Good absorbed from the gastrointestinal tract of the locations and parenteral administration. Time to maximum concentration after intramuscular administration of 1 to 2 hours. The connection to plasma proteins 95% (so weakly dialyzed). It is metabolized in the liver, elimination half-life of 15-30 hours, most metabolites are pharmacologically inactive. Excreted by the kidneys and the bile. Triftazin crosses the placenta.

Indications for use:

schizophrenia and other mental illnesses, nadrolone occurring with delusions, hallucinations and psychomotor agitation;

vomiting of central origin.

Contraindications:

increased individual sensitivity;

inhibition of the function of the central nervous system and comatose states from any cause;

brain injury;

liver disease, kidney and blood-forming organs in violation of the functions;

progressive system of the brain and spinal cord diseases;

peptic ulcer and 12 duodenal ulcer during the exacerbation;

heart failure in the stage of decompensation; severe hypotension; diseases accompanied by the risk of thromboembolic complications;

angle-closure glaucoma (risk of increased intraocular pressure);

prostatic hyperplasia;

myxedema;

pregnancy, breast-feeding;

Children up to age 3 years.

Precautions:
elderly, vomiting (antiemetic effect of phenothiazines may mask vomiting associated with an overdose of other drugs.).

Triftazin used after comparing the risks and benefits of treatment in patients with alcohol intoxication, Reye’s syndrome, cachexia, as well as breast cancer, Parkinson’s disease, gastric ulcer and duodenal ulcers, urinary retention, chronic respiratory diseases (especially in children), epileptic seizures.

Dosage and administration:

Triftazin Inside, after a meal.

Doses are selected individually according to the severity of the condition, for the dose titration should be used with the appropriate dosage forms (lower) dose. When nadrolone the maximum therapeutic effect dose was gradually reduced to maintenance. Usually, for the treatment of anxiety disorders adults appoint 1 mg 2 times a day. For patients with psychotic disorders begin to 2 mg 2-5 times a day. For optimal therapeutic effect dose gradually increased to 15-20 mg / day, divided by 2-3 hours, maximum daily dose – 40 mg.

To obtain the desired therapeutic effect and improvement of the patient must usually 2-3 weeks.

6-12 years old children, psychotic disorders, administered at 1 mg 1 -2 times a day, the dose may be increased to 4 mg / day as needed. The dose for children over 12 years – 5-6 mg per day, divided into several stages.

Adults with vomiting – 1-2mg 2 times a day. For elderly patients the initial dose should be reduced by 2 times.