Anti-WNV Envelope protein DI-DII [E53]

Clone Number: E53Description: Recombinant monoclonal antibody to WNV Envelope protein DI-DII. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma E53.
Alternative Name(s) of Target: EP; E protein
Immunogen: Specificity: This antibody binds to the Envelope protein fusion-loop DI-DII of West Nile virus.Application Notes: This antibody binds the fusion loop of West Nile Virus virions and neutralizes mature virions in a temperature- and time-dependent mannerAntibody First Published in: Dowd et al. A Dynamic Landscape for Antibody Binding Modulates Antibody-Mediated Neutralization of West Nile Virus PLoS Pathog. 2011 Jun; 7(6): e1002111. PMID:21738473Note on publication: Describes the characterization of the neutralizing effect of this antibody.
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Published Application(s): NTRL; crystallographyPublished Species Reactivity: