Summaries for Neonatal Progeroid Syndrome

NIH Rare Diseases:41 Neonatal progeroid syndrome is a premature aging syndrome in which features of human aging are apparent at birth, including larger than nomal sized head; prominent scalp veins; triangular, aged face; wrinkled skin; and decreased fat under the skin. this differentiates this syndrome from other premature aging syndromes such as hutchinson–gilford progeria syndrome (hgps) (more commonly called progeria) in which characteristics of premature aging typically become apparent some time after birth. although the exact cause of neonatal progeroid syndrome is unknown, it is believed to be genetic and inherited in an autosomal recessive fashion. treatment is based on the individual's specific symptoms.
last updated: 2/16/2010

MalaCards based summary: Neonatal Progeroid Syndrome, also known as wiedemann-rautenstrauch syndrome, is related to entropion and marfan syndrome, and has symptoms including narrow mouth, abnormality of the fontanelles or cranial sutures and macrocephaly. An important gene associated with Neonatal Progeroid Syndrome is IGF1 (insulin-like growth factor 1 (somatomedin C)). Affiliated tissues include skin, bone and testes.