OpenCyc is the open source version of the Cyc(r) technology, the world's largest and most complete general knowledge base and reasoning engine. A new release with even more content, better performance, and improved reliability will be up shortly.

pyOBD-II (a.k.a. "pyobd2") is a Python library for communicating with OBD-II vehicles. Its goal is to make writing programs for vehicle diagnostics and monitoring vehicle data as easy as possible. Relies on pySerial to communicate with ELM scanners.

vb2py is developing a VB to Python tool for automatically converting VB projects to Python, including both the code and GUI elements. The project is currently focussing on the PythonCard GUI system on the Python side