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Pregnant porn star Elektra Luxx is trying to make a living teaching sex classes to housewives. But her life is thrown into disarray when a flight attendant with ties to Elektra's past approaches her for a favor. Chaos ensues as fiancés, private investigators, a twin sister and even the Virgin Mary force her to face up to an unexpected series of decisions and revelations in her life.

The film ends with the trailer for Elektra's farewell film, the Spaghetti Western spoof Even Reverse Cowgirls Get the Blues.

Sebastian Gutierrez is planning a third installment tentatively titled Women in Ecstasy, which will feature Carla Gugino, Adrianne Palicki, Emmanuelle Chriqui, Joseph Gordon-Levitt, and several cast members returning from Women in Trouble.[3]