2013-01-30T09:20:17Z100Falseapplication/pdfXYW76KROUJlate-lessons-ii-chapter-28 Late lessons from early warnings II - In conclusion Implications for science and governance | In conclusion
28 In conclusion
Since 2001: many changes, crises and
lessons relearnt
The first volume of Late lessons from early warnings
was published in 2001. Since then, the world has
changed significantly. It is larger in population
but smaller in interconnectivity; faster in terms
of technology adoption but slower in terms of
policy action in the face of complex interlinked
problems; more volatile in terms of economic and
environmental changes, yet more static in terms of
political reflexivity and adaptations in governance.
Beyond the current financial and economic
crises, there are several long-term, systemic and
interconnected challenges, such as depletion of
natural resources, climate change, a 2-billion
person increase in the world population by 2050,
and diminishing ecosystem resilience (EEA, 2011a;
OECD, 2012; WEF, 2012).
These developments point to two important realities.
First, the systems of governance misrepresent
the socio-ecological system, making societies and
the environment subordinate to the economy
— essentially serving as sources of human and
natural capital. This misrepresentation ignores the
reality that any civilisation is ultimately dependent
on its ecological and social foundations and
that economies function to sustain and enhance
human well-being (Passet, 2001). Second, the
scale, interconnectedness and sheer complexity of
feedbacks between nature and human interventions
have outstripped society's capacity to understand,
recognise and respond to these effects.
The first volume ended with a call to action for
policymakers. How much progress has been made
since then? One important area is that of innovation
and the effect that precaution can have on it. In
Volume 1, the difficulties of balancing precaution
with technological innovation were recognised.
However, there is now increasing evidence that
precautionary measures do not stifle innovation, but
can encourage it, in particular when supported by
smart regulation or well-designed tax changes (EEA,
2011b, 2011c; Ambec et al., 2011; Ashford and Hall,
2011).
670
Volume 1 also invited policymakers to take more
account of a 'richer body of information from
more diverse sources'. It identified public health
and the environment as two fields of science that
were separate and polarised. And it suggested
involving a wider range of stakeholders to expand
the information base and to 'improve public trust in
society's capacity to control hazards, without stifling
innovation or compromising science'. These are all
areas where improvements have been made since
2001.
There has been less progress with other lessons,
particularly the call to 'identify and reduce
institutional obstacles to learning and action'. Both
political and scientific 'bureaucratic silos' do not
seem to have disappeared, despite the frequent
calls for policy integration and inter-departmental
coordination (Hamdouch and Depret, 2010; Phoenix
et al., 2012).
Worryingly, warnings of impending hazards are, in
many areas, still not being heeded and the resulting
damage is far more widespread, geographically,
across species and extending to future generations,
who will particularly suffer many of the harmful
effects of our current energy systems, chemicals and
technologies. Damage is now shown to be occurring
at increasingly lower levels of exposure to pollution,
and the polluters, for the most part, are still not
paying the full costs of their pollution, partly
because of a lack of incentives to do so. At the same
time we see the destruction of the stocks of natural
capital that underpin human well-being. It is easy to
lose sight of the crucial dependence of economies on
a diverse, healthy and resilient natural environment,
especially in times of economic crises.
A key message in the 2001 report was the notion
that 'the growing innovative powers of science
seem to be outstripping its ability to predict the
consequences of its applications, while the scale
of human interventions in nature increases the
chances that any hazardous impacts may be serious
and global.' This is happening at an ever-greater
pace, with globalised industries racing to introduce
new technologies but with limited understanding
Late lessons from early warnings: science, precaution, innovation
Implications for science and governance | In conclusion
of what their impacts might be. National
governments now have less control over globalised
technologies.
More positively, however, new transformative
approaches are emerging for managing the
systemic and interconnected challenges that we
face (e.g. Gladwell, 2012; Stirling, 2008). They
are building in particular on the increasing use
by consumers, citizens and shareholders of the
power of the internet and social media to demand
and foster increased participation, responsibility,
accountability and transparency.
Such approaches also need longer-term perspectives.
Greater complexity, uncertainties, scientific
ignorance, broader risks and the irreversibility of
many harmful impacts together necessitate the
increased use of long-term scenarios and strategy
analysis by citizens, governments and corporations
alike (EEA, 2011a). The long-term interests of society
as a whole, distinct from the partial interest of
particular stakeholders and individuals, also require
new political and financial institutions that can help
overcome the short termism of most politics and
much finance (Ward, 2012; Roderick, 2010; Mainelli
and Giffords, 2009; RMNO, 2009).
The case studies in this second volume of Late
lessons from early warnings provide some new
insights from the lessons of the past that can help
stimulate actions to reinforce, complement and
put into practice the emerging transformative
approaches, mindful of the observation that 'those
who cannot remember the past are condemned to
repeat it' (Santayana, 1905).
2001–2013: what new insights emerge?
Many of the cases in this report reveal similar
lessons to those in the 2001 report. Some insights
have been strengthened, however, as the body of
evidence has increased and our understanding of
ecological and biological systems has improved. The
case studies in the two volumes of Late lessons from
early warnings cover a very diverse range of both
recent and historical chemical and technological
innovations and their impacts on humans and
nature. All cases have unique characteristics
stemming from the type of the innovation, the
origins and nature of the hazards, the prevailing
approaches to policymaking, and the cultural
influences of time and place. The studies also
share common features, such as key decisions on
innovation pathways made by a few people on
behalf of many; a lack of institutional and other
mechanisms to respond to early warning signals;
misleading market prices that do not properly
reflect all costs and risks to society and nature; and
inadequate accounting for assets and liabilities
across different types of capital.
Such features from the past raise questions for
the future. How, for example, can the innovations
that are driving knowledge economies, such as
nanotechnologies, be developed without repeating
the mistakes of the past? How can the wider and
wiser application of the precautionary principle
support decision-making in the face of uncertainties
from within complex systems that defy prediction
and where 'surprises' are inevitable? How can we
ensure that the lack of 'perfect' knowledge is not
a justification for inaction in the face of 'plausible'
evidence of serious harm? How can conflicting
interests (including public and private ones) be
balanced in the development, use and impact
phases? How can the distribution of costs and
benefits over time be made more equitable?
The Late lessons from early warnings case studies
demonstrate the complexities of handling the
interactions between the many actors and
institutions involved — governments, policymakers,
businesses, entrepreneurs, scientists, civil society
representatives, citizens and the media. Each comes
to the debate with different and often conflicting
knowledge, perceptions, interests and priorities;
balancing these numerous and often antagonistic
positions should be seen as a prelude to making
decisions on those innovations that have broad
societal implications.
The opportunities are manifold but can be boiled
down to three main ones:
• to correct the prioritisation of economic and
financial capital over social, human and natural
capitals through the broader application of the
policy principles of precaution, prevention and
polluter-pays, and improved accounting systems
across government and business;
• to broaden the nature of evidence and public
engagement in choices about crucial innovation
pathways by balancing scientific efforts more
towards dealing with complex, systemic
challenges and unknowns and complementing
this knowledge with lay, local and traditional
knowledge;
• to build greater adaptability and resilience
in governance systems to deal with multiple
systemic threats and surprises, through
Late lessons from early warnings: science, precaution, innovation
671
Implications for science and governance | In conclusion
strengthening institutional structures and
deploying information technologies in support
of the concept of responsible information and
dialogues.
Taken together the case studies provide some
lessons to support action, supplementing the
conclusions of Volume 1. These findings are
presented in the remainder of this section.
Reduce delays between early warnings and actions
Most of the case studies in both volumes of Late
lessons from early warnings illustrate that if the
precautionary principle had been applied on the
basis of early warnings, many lives would have
been saved and much morbidity and damage to
ecosystems would have been avoided.
Today, several factors related to the speed, scale
and breadth of technological innovation exacerbate
the tendency to delay action. First, by the time
evidence of harm is confirmed, the technology has
often changed, leading to assumptions that, unlike
yesterday's technology, today's technology is now
safe. Second, for some technologies (e.g. broadscale energy production systems or chemical
plants), the huge initial investments mean that
yesterday's investments will be redeemed before
any serious risk reduction is implemented, creating
de facto technological lock-ins. Third, the scale of
technological development puts very difficult
demands on those attempting to monitor and
respond to the risks before they have become
serious, widespread and irreversible.
These features of contemporary life further
strengthen the case for taking early warning signals
more seriously and acting on lower strengths of
evidence than those normally used to adduce
'scientific causality'.
The case studies have shown that the main barriers
to timely action include the short-term nature
of many political and financial horizons; the
novel and challenging nature of the technologies
and the scientific problems that arise from their
interactions with complex biological, ecological
and social systems; the conservative nature of
much environment and health science; the ways in
which scientific and other evidence is evaluated;
the different perspectives and interests of many
stakeholders and the vested interests of some
powerful ones; and the broader cultural and
institutional circumstances of public policymaking
that often favour the status quo.
672
Addressing these causes of delay can help to
reduce the negative impacts that arise from many
innovations. But tackling them is not easy. For
example, the problem of the unequal distribution
of political power between citizens, business and
financial actors, and governments is a persistent
problem of politics, which has increased through
globalisation and the rise of multinational
corporations, yet it is an issue that is well beyond
the scope of this report. Some of the other causes of
delay are more amenable to change and these are
addressed in the rest of this section.
In evaluating the pros and cons of using the
precautionary principle, it is important to remember
that the harm from most hazards analysed in the
case studies turned out to be more diverse and
widespread than anticipated and such damage
is often found to occur at exposures lower than
initially considered dangerous.
For example, it has been known since 1960 that
asbestos causes the mesothelioma cancer, in addition
to lung cancer (identified in 1955) and asbestosis
(identified in 1906–1929). Similarly, it is now known
that smoking causes a wide range of cancers, heart
disease and foetal damage, beyond the harm of
lung cancer identified in 1951. PCBs are now known
to cause neurological problems in children, and
cancer, in addition to harming the reproduction
of eagles (identified in the 1960s). Lead has also
been demonstrated to be more broadly chronically
harmful — it was initially recognised as damaging
children's IQ but it is now known to cause heart
disease in adults. Radiation has gone through a
similar expansion of known hazards.
This phenomenon of 'harm expansion' is rendered
more problematic by the discoveries that harm from
all of the above agents has been found to occur at
lower and lower levels, such that, more often than
not, no 'safe' threshold of exposure can be identified.
This knowledge needs to be taken into account
when evaluating the potential pros and cons of
future precautionary action on emerging issues.
Continuous, anticipatory reductions in exposures
to emerging hazards could help to avoid repeating
these histories of harm expansion.
More and better prospective and retrospective
analyses of the costs of action and inaction, across
the full lifecycle of a technology, would highlight
the value of precautionary and preventive actions,
particularly the value of 'secondary benefits and
costs' which can be substantial, such as the health
benefits from reduced fossil fuel use, where the
main objective is to mitigate climate change. They
Late lessons from early warnings: science, precaution, innovation
Implications for science and governance | In conclusion
should also consider the psychological and societal
costs of both false alarms concerning a health
hazard, e.g. the over-reaction to swine flu in the US
in the 1970s, and misplaced reassurances concerning
the safety of a technology, such as the downplaying
of risks associated to nuclear power plants by
Japanese authorities and utilities. Such pro and
con analyses should be independent of interested
parties, both commercial and political, as they often
have a 'natural' tendency to exaggerate costs of
hazard reduction and to underestimate the benefits
of action.
As case studies from both volumes have also shown,
the timely use of the precautionary principle can
often stimulate rather than hamper innovation,
in part by promoting a diversity of technologies
and activities, which can also help to increase the
resilience of societies and ecosystems to future
surprises. Keeping options open and following
multiple paths means that a particular option can
be terminated if it turns out to pose high risks, and
avoids situations of technological monopolies such
as those experienced, for example, in the cases of
asbestos, CFCs and PCBs.
balance between generating false negatives and
false positives; and the social necessity of large-scale
innovations.
Clearly, acting to avoid or reduce harm on lower
strengths of evidence than that used to establish
scientific causality will sometimes increase the
number of false alarms — although the review of 88
cases of alleged false positives in Volume 2 of Late
lessons from early warnings confirmed just four actual
cases, suggesting that the risks are considerably less
than sometimes claimed. Moreover, it is important
to recognise that, in cases where there are damages
over a long time span that may irreversibly alter
the system, there is a fundamental asymmetry
between the competing policy and scientific
options of avoiding false negatives and avoiding
false positives. Examples of such situations of
irreversibility include climate change, modification
to the genetic make-up of humans or other species,
persistent chemical or radioactive contamination,
and species loss.
In contrast, technological monopolies hamper
innovation. For example, it was the monopolies of
lead in petrol, asbestos, CFCs and PCBs that both
prolonged the harms they caused and made those
harms widespread. These monopolies contributed
to technological 'lock-in' but also to institutional
and ideological lock-ins, which further hampered
innovation and the development of alternatives.
These technologies and their products were also
'cheap' in the market place, bearing little relation to
their real costs in terms of harm to the environment,
human health and financial compensation to
victims. These artificially low market prices in
turn helped to stifle the development of smart
substitutes.
If an early warning signal triggers a double reaction
of precautionary policy measures and more
intensive research on risks and alternatives, then
at some point the research may show that this was
a false alarm and the precautionary measure can
be cancelled. The loss in this case will be a delay in
economic and social benefits from the technology
(or the cost of mitigating actions in cases such as
climate change) during the time it took to show
that there was no cause for concern. But the system
will not be irreversibly altered. In contrast, if the
early warning triggers no precautionary action but
more research shows, only much later, that there
was indeed real cause for concern then irreversible
systemic damages will already have taken place.
Acknowledging this asymmetry is central to
understanding when precautionary and preventive
approaches are best deployed.
This past experience should be taken into account
with the emerging technologies such as GMOs and
nanotechnologies, where there are already signs of
technological monopolies, driven by the high costs
of research, development and production involved
and the patent protections for developers on many
of their products and processes (Stirling, 2007; van
den Hove et al., 2012).
Tipping the overall balance of public policy towards
avoiding harm, even at the cost of more false alarms,
would seem to be a price that is well worth paying,
given the costs of being wrong in acting or not
acting. This is one of the strategic and ethical societal
choices, similar to the choice of strengths of evidence
to be used in civil or criminal court cases, that needs
to be openly debated.
When applying the precautionary principle, there
are, therefore, not only scientific issues to be
considered but also ethical choices, concerning
the appropriate strength of evidence for action;
the equity implications arising from the costs and
benefits of action and inaction; the appropriate
Acknowledge complexity when dealing with
multiple effects and thresholds
The world is drawing down its natural capital
through an over-reliance on fossil-fuel-based,
Late lessons from early warnings: science, precaution, innovation
673
Implications for science and governance | In conclusion
synthetic chemicals that are compromising the
health and resilience of ecosystems and key
organisms such as fish and bees, in combination
with other stressors such as climate change and
invasive alien species. There is also evidence that
some types of genetically modified crops (and the
agrochemical substances used alongside them),
which are released into the environment and the
food chain, present a threat to human health, some
species and ecosystems, and food security. Human
health is being further compromised by chemicals
that threaten health from before birth, through
childhood and into adulthood. (Barouki et al., 2012;
EEA, 2012; Kortenkamp et al., 2011).
Such exposures appear to contribute to increases
of many types of cancers, birth defects, male
infertility, and cardiovascular, neurological and
immunological dysfunctions and diseases. The
impacts of these hazards are being supplemented
by the harmful effects of unhealthy eating habits
and lifestyles in many parts of the world, and
resulting in epidemics such as diabetes and obesity.
Taken together, these multiple stressors have
profound public health significance.
Growing scientific knowledge clearly shows that
the causal links between stressors and harm are
more complex than was previously thought and
this has practical consequences for minimising
harm. Much of the harm described in Volumes 1
and 2, such as cancers or species decline, is
caused by several co-causal factors acting either
independently or together. For example, the
reduction of intelligence in children can be linked
to lead in petrol, mercury and PCBs as well as to
socio-economic factors; bee colony collapse can be
linked to viruses, climate change and nicotinoid
pesticides; and climate change itself is caused
by many complex and inter-linked chemical and
physical processes.
In some cases, such as foetal or fish exposures,
it is the timing of the exposure to a stressor that
causes the harm, not necessarily the amount;
the harm may also be caused or exacerbated
by other stressors acting in a particular timed
sequence. In other cases, such as chemicals like
BPA, low exposures can be more harmful than
high exposures; and in others, such as asbestos
with tobacco, and some endocrine disrupting
substances, the harmful effects of mixtures can
be greater than from each separate stressor.
There are also varying susceptibilities to the
same stressors in different people, species and
ecosystems, depending on pre-existing stress
levels, genetics and epigenetics. This variation can
674
lead to differences in thresholds or tipping point
exposures, above which harm becomes apparent in
some exposed groups or ecosystems but not others.
Indeed there are some harmful effects that occur
only at the level of the system, such as a bee colony,
which cannot be predicted from analysing a single
part of the system, such as an individual bee.
The increased knowledge of complex biological
and ecological systems has also revealed that
certain harmful substances, such as PCBs and
DDT can move around the world via a range of
biogeochemical and physical processes and then
accumulate in organisms and ecosystems many
thousands of kilometres away. The practical
implications of these observations are threefold.
First, it is very difficult to establish very strong
evidence that a single substance or stressor 'causes'
harm to justify timely actions to avoid harm; in
many cases only reasonable evidence of co-causality
will be available. Second, a lack of consistency
between research results is not a strong reason for
dismissing possible causal links: inconsistency is to
be expected from complexity. Third, while reducing
harmful exposure to one co-causal factor may not
necessarily lead to a large reduction in the overall
harm caused by many other factors, in some cases
the removal of just one link in the chain of multicausality could reduce much harm.
A more holistic and multi-disciplinary systems
science is needed to analyse and manage the causal
complexity of the systems in which we live and
to address long-term implications. For example,
there would be substantial benefits from exploring,
much earlier and more systematically, the multiple
effects on people and ecosystems of chemical
and other stressors, their cumulative effects,
chemical metabolites, and their mixture effects.
Exposures to low doses of contaminants and their
effects, particularly in susceptible sub groups in
populations, should also be more fully investigated,
accompanied by more biological monitoring that
would improve the detection of the precursors of
disease.
Several case studies provide examples of where
assertions that 'no evidence of harm' have been
interpreted as 'evidence of no harm', which may
not be the case if appropriate research over relevant
time periods is missing. Examples include leaded
petrol in the 1920s-60s, and risks to children from
mobile phones before 2011, when the first study
on children was published. Such authoritative but
unsubstantiated assertions of safety have led to
much harm, for example, in cases such as asbestos,
tobacco, lead and mercury.
Late lessons from early warnings: science, precaution, innovation
Implications for science and governance | In conclusion
Acknowledging both uncertainties and scientific
ignorance is particularly important where the
science is relatively immature, as with such
emerging technologies as GM crops, mobile phones,
nanotechnology and invasive alien species and
where exposures are widespread. Recognising
uncertainty also helps to avoid putting too much
reliance on simple models of complex systems as
in the cases of floods, nuclear accidents, climate
change, ecosystems resilience and multi-pollutant
human exposures
Uncertainty, though, can be a two-edged sword,
being used as the basis for challenging both
assurances of safety and evidence of a hazard.
In particular, uncertainty has been misused,
exaggerated, or even 'manufactured' in order to
delay and undermine regulatory measures to protect
health and environments. Examples include climate
change, tobacco, lead, honeybees and beryllium
(Michaels, 2008; Oreskes and Conway, 2010).
There is also an asymmetry between the high
levels of proof of harm demanded by proponents
of a technology as sufficient to justify remedial or
preventive actions compared to the level of evidence
they deem sufficient to claim that their products are
'safe'. Waiting for high levels of proof of harm before
acting not only leads to much harm but also to a
stifling of innovation, as the case studies on asbestos,
lead, mercury, PCBs and CFCs illustrate.
Rethink and enrich environment and health research
The need for research to focus more on the potential
hazards of emerging technologies in addition to
research on product applications has already been
noted. It would also be helpful if there were a
greater focus on emerging hazards rather than on
well-known risks. Recent research (Grandjean et
al., 2011) indicates that much environmental health
research still focuses on well known hazards, such
as lead and mercury, and tends to ignore newly
emerging threats to health. The top ten substances
studied are all metals such as copper, lead, zinc
and cadmium. These established hazards account
for approximately half of all the journal articles
on impacts of chemical substances of the last ten
years (Grandjean et al., 2011). This disproportion
has crowded out research into other dangerous
hazards and risks, such as on endocrine-disrupting
substances and other hazards where less is known
about their pathways and impacts (despite over EUR
100 million of EU research funding on endocrine
disrupting compounds in the last decade) but where
the evidence is growing of widespread impacts on
humans and nature (EEA, 2012; Kortenkamp et al.,
2011).
A major reason for this imbalance may relate to the
prevailing regulatory science paradigm, where solid
conclusions depend on replication and verification.
Other likely contributing factors to scientific inertia
are the effective use of costly infrastructure to ensure
value for money; the desire of policymakers for more
certainty from science regarding politically difficult
choices; and the tendency of funding agencies to be
conservative in their research strategies.
In order to identify hazards that may only appear
over decades, there needs to be more long term
monitoring of biological and ecological systems,
focusing on 'surprise sensitive' parameters such
as bees, amphibians, invertebrates, foetuses etc.
Such monitoring will also be essential to evaluate
the effectiveness of the precautionary and later
measures to avoid harm. Monitoring can be
supported in part by citizen scientists, using the
latest geographical information systems (GIS) and
monitoring technologies.
Several cases highlight the benefit of having lay and
local knowledge alongside scientific evaluation of
harm so that a broader knowledge base can support
decision-making. For example, when a mother
hypothesised that neurological signs observed in
her son were due to exposure to mercury in her
womb, this was dismissed by experts who did
not question their assumption that the placenta
provided protection (see Chapter 5 on Minamata
disease). Patients, fishers, wives (e.g. in the sperm
damaging, described in Chapter 9 on DBCP),
mothers (see Chapter 5 as well as and the chapter
on DES in Volume 1 (EEA, 2001, Ch. 8)), factory
workers, and bee keepers, as well as clinicians and
factory inspectors are amongst those non-scientists
who have reliably provided early warnings in the
case studies.
Precautionary actions are justified by lower strengths
of evidence than those conventionally used for
establishing scientific causation, yet in their search
for 'certainty' scientists are cautious in attributing
causation to an agent while some scientists may
sometimes be less cautious when asserting 'safety'.
The case studies show that in the past there have been
premature assertions of safety based on inadequate
scientific methods, such as an over-reliance on studies
that were conducted over too short a period to reveal
long-term effects for example.
Also evidence of harm has often had to reach the
high standard of 'causality' as is the standard for
Late lessons from early warnings: science, precaution, innovation
675
Implications for science and governance | In conclusion
less complex situations, rather than precautionary
strengths of evidence based on plausible association
between hazards and harms. The strength of
evidence chosen can range from 'a scientific
suspicion' of harm to 'beyond all reasonable doubt',
depending on the complexity of the system, the
level of protection required and the pros and cons of
being wrong in acting or not acting.
environmental science to become more attuned to
the inherent complexities of socio-ecological systems
by, for example, balancing a traditional disciplinary
focus with more holistic cross-disciplinary scientific
research, thereby complementing precision with
relevance and comprehensiveness (Phoenix et al.,
2012). Such science would often embrace longer
timescales, more end-points, and multi-causality.
To avoid waiting for strong evidence of harm in
humans and ecosystems, data from animal or
other species and methods (ECVAM), should be
more widely used to justify precautionary action.
This is particularly needed where the potential
damage is irreversible — as with some cancers,
species and ecosystems losses, and reproductive or
developmental effects.
Since the first volume of Late lessons from early
warnings, scientific approaches such as 'sustainability
science', 'systems biology' or 'futures research' have
continued to emerge to help deal with some of the
challenges arising from the interconnections and
dynamics of socio-ecological systems, focusing
on analysis and interventions at the systems level.
These emerging disciplines can also help build
bridges between research, policy communities, other
stakeholders and the public (Kates, 2011).
Research, precaution, and exposure control also need
to be applied to the substitutes or alternatives to
hazardous agents. The chapters on perchloroethylene
(Chapter 4), leaded petrol (Chapter 3), DDT
(Chapter 11) and booster biocides (Chapter 12)
as well as the chapters on CFCs and MTBE in
Volume 1 (EEA, 2001, Ch. 7 and Ch. 11) illustrate
the hazards that some alternatives have brought in
the wake of banned substances, especially when the
alternatives are chemically very similar (e.g. HFCs
for CFCs). Minimising the hazards of alternatives
could be helped by the avoidance of such chemical
characteristics as persistence, bioaccumulation,
and large spatial range; by the hazard screening of
alternatives; and by the greater use of the knowledge
to be found in smarter and greener chemistry and
technology.
Greater awareness of the complexity,
interconnectedness, multi-causality and
uncertainties inherent in global environmental
issues underlines the need for greater humility
about what science can and cannot tell us.
Framing issues as purely scientific and technical
inappropriately places scientific perspectives above
equally valid social and ethical contributions that
should be part of decision-making. A shift is needed
to more explicitly integrative environmental science
approaches in support of public policy, in which
systemic considerations and early warnings feature
strongly. This shift has started to take place in
discourses but often not in practices.
The case studies in Volume 2 of Late lessons from early
warnings also illustrate how regulatory health and
environmental science is still defined in very narrow
terms, which obstructs it from being able to identify
the complex multifactorial stresses on environmental
systems and humans. There is therefore a need for
676
Last but not least, the case studies show that early
warners — scientists and others — have often
been harassed for their pioneering work which
threatened economic interests and often challenged
conventional scientific paradigms. This harassment
can include bans on speaking out or publishing;
loss of funding; legal or other threats; demotion;
transfer to other work and character assassination
in scientific and other media (McCulloch and
Tweedale, 2007; Martin, 1999, 2008; UCS, 2012). Such
early warners should receive better protection via
the extension of 'whistle blowing' and discrimination
laws; by more active support and protection from
scientific societies in the case of scientists; and by
awards that acknowledge the value of their work.
Improve the quality and value of risk assessments
Volume 1 stressed the differences between risk,
uncertainty and scientific ignorance, and the
need to acknowledge and identify all three when
doing evaluations of evidence, as in formal risk
assessments. Since 2001, some considerable progress
has been made in characterising uncertainties in
risk assessments, for example, in the food industry
(EFSA, 2006, 2013), the field of emerging risks
(SCENIHR, 2012), and in climate change (IPCC,
2010). This recognition of uncertainty and ignorance
is particularly important where there is much
reliance on modelling, as in climate change, invasive
alien species, or exposure assessment.
The majority of case studies indicate that it is often
inappropriate to use a narrow conception of 'risk'
to manage the complex issues at hand with their
inevitable features of ignorance, indeterminacy
Late lessons from early warnings: science, precaution, innovation
Implications for science and governance | In conclusion
and contingency. The increasing awareness of
the complexity of biological, ecological and
technological systems, calls into question the
relevance and prevalence of some of the simplistic
methods, models and assumptions used in risk
assessments. For example, linear dose response
curves can be inappropriate when low doses are
more harmful than high doses, as in the BPA story;
the dictum that the dose alone 'makes the poison'
is inaccurate when it is the timing of the dose that
makes the dose harmful, as in the TBT and DES
cases; assuming uni-causality is too simplistic when
multi-causality is the reality, as in the lead case
study and many ecosystems such as fisheries; testing
for single substances is inadequate when mixtures
are present as in all cases of chemical exposures;
and there can be an over-reliance on statistical
significance when use of confidence limits would be
more appropriate.
Simplistic assumptions are also observed in
technological risk assessments. As the Fukushima
Investigation Committee (NAIIC, 2012) concluded,
'the accidents present us with crucial lessons on
how we should be prepared for 'incidents beyond
assumptions'. With its failure to plan for the cascade
effects beyond design–base accidents 'the regulatory
emphasis on risk based probabilistic risk assessment
has proven very limited'.
In other words, narrow risk assessment approaches
are now outstripped by the realities that they cannot
address, recognise and communicate. Too often this
contributes to effective denial of those risks that
do not fit the risk assessment frame. It is therefore
urgent to transform risk assessment practices
to make them broader-based, more inclusive,
transparent and accountable. That should also
enable more transparent communication of diverse
scientific views, especially on emerging issues
where the uncertainties and ignorance are high and
genuine differences of scientific interpretations are
likely, desirable, and defensible (Stirling, 2010).
In practice, risk assessments could be improved
by including a wider range of stakeholders
when framing the scientific risk agenda, through
ensuring all available evidence is readily accessible,
by broadening the scope and membership of
risk evaluation committees, by increasing the
transparency and consistency of committee
approaches and methods, and by ensuring their
independence of vested interests. Improvements in
transparency were recently announced by EFSA,
who wish all data submitted as part of the product
authorisation procedure to be made publicly
available, (EFSA, 2013).
The case studies on mercury, nuclear accidents,
leaded petrol, mobile phones, BPA and bees, have
shown that there can be significant divergence in the
evaluations of the same, or very similar, scientific
evidence by different risk assessment committees.
It is often not clear from their published reports
why this is so. It would be helpful if each risk
assessment report explained the committee's choice
of paradigms, assumptions, criteria for accepting
evidence, weights placed on different types of
evidence, and how uncertainties were handled.
This would also help reduce the confusion amongst
users of such divergent risk assessments when
they are faced with very different evaluations of
essentially the same evidence. It would also help
people to recognise the difference between 'settled
fact, majority opinion, legitimate minority view,
and unsubstantiated assertions' (Weiss, 2002).
Moreover, it is helpful if the sources of finance for
the research studies under consideration are made
explicit because of the 'funding bias' that has been
observed in research on issues such as tobacco,
pharmaceuticals, food, BPA, GM products and
mobile phones.
The case studies on bees, lead, BPA and nuclear
accident risks have shown that the scope and
membership of some risk assessment committees
have been too narrow, and they have sometimes
been dominated by one discipline or paradigm
with shared assumptions which are not therefore
questioned. Risk assessments can be made more
reliable if they embrace all relevant scientific
knowledge and approaches. For example
endocrinology currently brings new insights
into hormonally active biological systems that
complement conventional toxicology. Toxicity test
methods and risk assessments can benefit from more
recent yet reliable scientific knowledge emerging
from academic research fields.
The case studies also show that toxicity tests
designed for acute effects are unlikely to be
relevant to chronic effects, and that novel
technologies, such as systemic pesticides that
replace sprayed pesticides or new chemical
compounds replacing earlier ones, usually need
novel risk assessments.
The value of being transparent about what is
known and not known and about uncertainties
and disagreements is equally pertinent. Scientific
conclusions should not be portrayed as if there is
consensus when there is not. Science by its nature
progresses by building on critical appraisal. Several
cases show that disagreement can be helpful to
decision-makers with a broader picture of the
Late lessons from early warnings: science, precaution, innovation
677
Implications for science and governance | In conclusion
alternative directions and options available before
making a decision.
The whole process of risk analysis which
includes risk assessments, risk management and
risk communication, would benefit from the
involvement of stakeholders, particularly when
framing the risk assessment and identifying options
for risk management. This is illustrated in Ch. 27 on
the precautionary principle.
Foster cooperation between business, government
and citizens
An element that is often missing from innovation
policies and practice is the recognition that
innovation should be considered as a means,
not an end in itself, and desirable to the extent
that it improves human health and well-being
while maintaining ecological resilience. Policy
formulation should start from these premises and
from a broader concept that includes not only
technological innovation but also non-technological,
social, institutional, organisational and behavioural
innovation (van den Hove et al., 2012).
In this framework, governments have at least
three roles: first, providing direction by putting
in place smart regulations and consistent market
signals; second, ensuring that the distributional
consequences of innovations are balanced between
risks and rewards across society; and third, fostering
a diversity of innovations so that the wider interests
of society take precedence over narrower interests.
Numerous case studies show that decisions to act
without precaution often come from businesses.
There are, however, several impediments to
businesses acting in a precautionary manner,
including a fundamental economic focus on
creating and increasing short-term economic
value for shareholders. There are also a number
of psychological factors involved that lead to a
so-called 'ethical blindness' or a 'self-serving bias'
whereby people largely (and often unconsciously)
tend to interpret ambiguous situations in their own
interests.
This report reveals interesting parallels between
older case studies and fast emerging issues such
as nanotechnologies, genetically modified crops,
new chemicals, and the possible link between brain
tumours and non-ionising radiation from mobile
phones. For example, only a very small number of
actors were involved in making strategic decisions
about lead in petrol in the USA in 1925 yet the
678
technology spread all around the world before being
phased out some 60 years later. With issues such as
GMOs in food and energy options for a low carbon
future, only a relatively few actors are involved in
choosing innovation pathways that will shape the
future of agriculture and energy supply and use for
many decades.
Governments and businesses could collaborate more
with citizens and civil society on publicly disclosing
and analysing the potential value conflicts entailed
in acting on early warning signals. Public disclosure
and a culture of transparency and open discussion
can in turn promote positive business attitudes
and innovations. As stressed above, in many cases,
accurate determination of risk is difficult and open
to disagreement, making engagement, openness and
transparency all the more important.
Involving the public can also help in choosing
between those innovation pathways to the future
(WBCSD, 2010; EC, 2011; WBGU, 2012); identifying
and prioritising relevant public research (e.g. Diedrich
et al., 2011); providing data and information from
other knowledge holders — including NGOs, lay
observers and citizens — in support of monitoring
and early warnings; improving risk assessments;
identifying and considering both alternatives to
potentially hazardous agents and the unintended
consequences of both actions and inactions on such
agents; striking appropriate trade‑offs between
innovations and plausible health and environmental
harms; and, making decisions about risk-risk
trade‑offs, such as the health benefits of consuming
fish which contains mercury and PCBs. In particular,
a feature of the studies is the top-down nature of
innovations — the history of antibiotics in animal
feed and lead in petrol, for example, show how a
very small number of people can take decisions
which have a major impact on millions. The public
should help shape the future, including helping to
choose strategic innovation pathways, for example,
to sustainable agriculture and low impact renewable
energy systems, by 2050.
The case studies also illustrate that there is often a
lack of public accountability and access to the private
research on which public protection authorities rely.
Such access would help to increase independent
verification of data submitted for licensing and would
increase public trust in the regulatory authorities at a
time when such trust in elites is very low.
Information and communications technologies
(ICT) and their role in transforming social behaviour
can help to engage the public on these issues. ICT
has spawned a wide range of new collaborative
Late lessons from early warnings: science, precaution, innovation
Implications for science and governance | In conclusion
tools and approaches, which, as we saw above, are
already transforming the dynamics of governance
and innovation, fostering two-way interactions,
and which can be used to support a more diverse
approach to engaging with citizens. Less positively,
ICT developments and access to knowledge may be
building barriers to collaboration by fostering more
hectic interactions and competition in the pursuit of
enhanced productivity, less face-to-face contact, and
less space for thinking through possible solutions
to complex realities. Creating the space for more
deliberative thinking and innovation could contribute
to more collaborative problem solving.
For public engagement to be effective there needs
to be adequate procedures for identifying and
including the relevant stakeholders and public
interest groups and for the provision of adequate
educational and financial resources to enable such
groups to play an effective role. Public engagement
can be encouraged and supported by substantially
improved and simpler access to relevant data and
information, building on the provisions of the Aarhus
Convention and national freedom of information
laws. Business concerns about confidentiality and
competitiveness can be overcome through judicious
use of information technologies to manage access
rights while maintaining transparency on how such
information has been used and the insights drawn.
Today there are large imbalances within publicly
financed research between product development
and the study of potential hazards, an imbalance that
seems to repeat the histories of better-known hazards.
In Europe for example, in the period 2002–2013,
about 1 % of the total amount that the EU Framework
Programmes of Research and Development allocated
to developing products from nanotechnologies,
biotechnologies and ICT was spent researching their
potential hazards. Research carried out by private
industry may well show a similar imbalance, but data
is not easy to obtain.
Correcting this imbalance between researching
innovations and their applications, and anticipatory
researching of potential hazards posed throughout
their life cycle (production, use, recycling and
disposal) can help avoid unequal distribution of costs
and benefits further down the line and support a
better public acceptability of such technologies.
Correct market failures using the polluter pays and
prevention principles
When evidence of initial harm emerges, the costs
of such harm need to be internalised into the prices
of polluting products, via taxes and charges, in line
with the polluter pays principle. The revenues could
be devoted partly to stimulating research into less
hazardous alternatives, as was the case in the US
with CFCs, and partly to reducing taxes and charges
on labour.
The pollution taxes/charges would rise or fall in line
with knowledge about increasing/decreasing harm
and this would help to level the market playing field
for innovative alternatives to the harmful products
that are otherwise subsidised by the external
costs of their pollution. Tax shifts from labour to
pollution and inefficient use of resources bring other
benefits such as increased employment, a stimulus
to innovation and a more efficient tax system
(EEA, 2011b and 2011c).
More realistic market prices, that reflect the true
economic, environmental and social costs, can
help encourage more sustainable behaviours
by governments, businesses and citizens. More
broadly, firms and governments need to extend their
accounting systems beyond economic and financial
capital considerations to incorporate the full human
and natural capital impacts of their activities,
building on developing practices worldwide
(UN, 2012; EEA, 2011d; Puma, 2011).
Many case studies also demonstrate the long time
lags between evidence of harm and the additional
injustice and time of forcing victims to pursue their
case through civil compensation claims. In the case
of Minamata this took over 50 years. Prompt and
anticipatory no-fault compensation schemes for
victims of harm and damage to ecosystems could
be set up and financed in advance of potential
harm by the industries that are producing novel
and large‑scale technologies, thereby helping to
correct this market failure. These schemes increase
incentives for innovating companies to carry out
more a priori research into the identification and
elimination of hazards.
Precedents exist for such schemes in some countries,
for example for nuclear accidents, oil spills, some
radiation exposures, and some environmental
liability laws, including contamination by GM crops
of adjacent non-GM farms. Within the schemes
there needs to be provision for penalising gross
negligence, which under a tort system justifies
punitive damages. Consideration also needs to
be given to the use of anticipatory liability bonds
by innovating companies so as to increase their
incentive to minimise hazards and to provide
adequate funds to compensate those who may
suffer from any harm that may arise from their
Late lessons from early warnings: science, precaution, innovation
679
Implications for science and governance | In conclusion
products. Re-insurance schemes are also playing a
role in helping to anticipate long tail liabilities from
emerging technologies.
Attributing responsibility and sometimes negligence
to corporations and others active in the history of
hazards has relied mainly upon evidence uncovered
by the legal processes of document discovery in
civil compensation cases. The further use and
development of freedom of information laws and
the Aarhus Convention could provide a speedier
means of accessing documented history. This will
be even more necessary if no-fault administrative
schemes replace some civil compensation cases.
Governance of innovation and innovation
in governance
This chapter opens with a picture of unprecedented
global change and interdependence. Such change
provides many benefits to societies but also exposes
them to more shocks and surprises. Scientific and
technological innovations proceed apace, more
often than not on trajectories that exacerbate risks
and threats. At the same time, those researching
and developing technological innovations often fail
to acquire relevant existing knowledge from other
disciplines. Governments tend to use structures
and methods from the past to monitor the potential
hazards of future technologies, rather than
implementing more advanced, flexible and relevant
approaches.
Failures, such as those presented in the two volumes
of Late lessons from early warnings, provide numerous
valuable insights, yet it appears that memories fade
quickly. Typically, a hazardous event generates a
sense of urgency and enthusiasm for strengthening
preparedness systems, initiating research and
implementing long-term monitoring, and heavy
expenditure often follows. In the aftermath of an
event, relevant authorities elaborate ambitious plans
and launch works, but lessons are soon forgotten.
After some time without adverse events, willingness
to invest in risk research, long-term monitoring etc.
decreases sharply and projects are downscaled or
suspended. Chernobyl and Fukushima are cases in
point.
This cycle of events is termed the 'hydro-illogical
cycle' in the case study on floods but could perhaps
be called the 'homo-illogical cycle' as it seems to be
a recurrent pattern for humankind, which is found
across many cultural, political, social and economic
systems. Despite its prevalence, this pattern need
not be inescapable. Humans can learn, change
680
and transform and there is enormous potential in
human creativity and its capacity to inspire cultural,
social, political, institutional, organisational and
behavioural innovation, beyond 'mere' technological
innovation. If, as Plato said, necessity is the mother
of invention, then the crises we are facing create a
level of necessity that will hopefully engender the
needed innovations.
Crucially, governance systems also need to better
recognise the value conflicts that are underpinning
all societal and environmental issues. They are
unavoidable and are even desirable as they are
constitutive of the human condition. What is often
missing is the institutional space to have a much
more systematic, and non-judgmental, analysis of
such conflicts so that they can be made explicit,
enabling policymakers and other actors to start
working together on the problems along the lines
described in this chapter.
Of course such analysis already takes place (in part)
in some quarters — examples include some
parliamentary commissions and non-governmental
organisations — but it is not sufficiently systematic
and does not always focus on value conflicts. There
could be merit in establishing a place in formal
institutional frameworks where such value conflicts
(and consequent conflicts of interests) could be
analysed and proposals offered for their resolution.
The ideas for the governance of innovation and
innovations in governance presented in this chapter
will remain at the level of good intentions unless
they are translated into institutional arrangements
and practices. This is the task that lies ahead.
References
Ambec, S., Cohen, M.A. Elgie, S. and Lanoie, P.,
2011, The Porter Hypothesis at 20. Can environmental
regulation enhance innovation and competitiveness?
Resources for the Future Discussion Paper 11/01.
Ashford, N.A. and Hall, R.P., 2011, 'The importance
of regulation-induced innovation for sustainable
development', Sustainability, (3/1) 270–292.
Barouki, B., Gluckman, P.D., Grandjean, P., Hanson,
M. and Heindel, J.J., 2012, 'Developmental origins
of non-communicable diseases and dysfunctions:
Implications for research and public health',
Environmental Health, (11) 42.
Diedrich, A., Upham, P., Levidov, L. and van
den Hove, S., 2011, 'Framing environmental
Late lessons from early warnings: science, precaution, innovation
Implications for science and governance | In conclusion
sustainability challenges for research and innovation
in European policy agendas', Environmental Science
and Policy, (14/8) 965–939.
'green economy': foundations and implementation
patterns', Journal of Environmental Planning and
Management, (53/4) 473–490.
EC, 2011, A roadmap to a competitive low carbon
economy in 2050, COM/2011/0112 Final.
ECVAM, http://ihcp.jrc.ec.europa.eu/.
IPPC, 2010, Guidance Note for Lead Authors of the IPCC
Fifth Assessment Report on Consistent Treatment of
Uncertainties, Intergovernmental Panel on Climate
Change.
EEA, 2001, Late lessons from early warnings: the
precautionary principle 1986–2000, Environmental
issues report No 22, European Environment Agency.
Kates, R.W., 2011, 'What kind of a science is
sustainability science?', Proceedings of the National
Academy of Sciences, (108/49, 99) 19 449–19 450.
EEA, 2011a, The European environment – state
and outlook 2010: assessment of global megatrends.
European Environment Agency.
Kortenkamp, A., Evans, R., Martin, O., McKinlay,
R., Orton, F. and Rosivatz, E., 2011, State of the Art
Assessment of Endocrine Disrupters report for the
European Commission, DG ENV., Brussels, 2011.
EEA, 2011b, Environmental tax reform in Europe:
implications for income distribution, EEA Technical
report No 16/2011, European Environment Agency.
EEA, 2011c, Environmental tax reform in Europe:
opportunities for eco-innovation, EEA Technical report
No 17/2011, European Environment Agency
EEA, 2011d, An experimental framework for ecosystem
capital accounting in Europe, EEA Technical report
No 13/2011, European Environment Agency.
EEA, 2012, The impacts of endocrine disrupters
on wildlife, people and their environments – The
Weybridge+15 (1996–2011) report, EEA Technical
report No 2/2012, European Environment Agency.
EFSA, 2006, Guidance of the Scientific Committee on a
request from EFSA related to Uncertainties in Dietary
Exposure Assessment Adopted on 14 December 2006
(http://www.efsa.eu./en/science/sc_commitee/sc_
opinions.html).
EFSA, 2013, 'EFSA promotes public access to data in
transparency initiative', 14 January 2013, European
Food Safety Authority, Parma, Italy.
Gladwell, M., 2012, 'Malcolm Gladwell: from
Hierarchies to Networks', (http://blog.nielsen.com/
nielsenwire/consumer/malcolm-gladwell-fromhierarchies-to-networks) accessed 6 December 2012.
Grandjean, P., Eriksen, M.L., Ellegaard, O., Wallin,
J.A., 2011, 'The Matthew effect in environmental
science publication: A bibliometric analysis of
chemical substances in journal articles', Environ
Health, (10) 96.
Hamdouch, A., Depret, M-H., 2010, 'Policy
integration strategy and the development of the
Mainelli, M. and Giffords, B., 2009, The road to Long
Finance: a systems view of the Credit Scrunch, Centre
for the Study of Financial Innovation, London.
Martin, B., 1999, Suppression of dissent in science
Research in Social Problems and Public Policy, Vol. 7,
edited by William R. Freudenburg and Ted I.K. Youn
(Stamford, CT: JAI Press, 105–135.
Martin, B., 2008, 'Enabling Scientific Dissent', New
Doctor, 88, December, Australia.
McCulloch J. and Tweedale, G., 2007, 'Shooting
the messenger: the vilification of Irving J. Selikoff',
International Journal Health Sciences, (37) 619–634.
Michaels, D. 2008, Doubt is their product: how
industry's assault on science threatens your health.
Oxford; New York: Oxford University Press, 372 pp.
NAIIC, 2012, The official report of The Fukushima
Nuclear Accident Independent Investigation Commission,
The National Diet of Japan.
OECD, 2012, Environmental Outlook to 2050: the
consequences of inaction, OECD, Paris.
Oreskes, N. and Conway E.M., 2010, Merchants of
Doubt: How a Handful of Scientists Obscured the Truth
on Issues from Tobacco Smoke to Global Warming,
Bloomsbury Press.
Passet, R., 2001, Manifeste pour une économie à finalité
humaine, Le Monde Diplomatique, Février, pp. 14–15.
Phoenix, C., Osborne, N.J., Redshaw, C., Moran, R.,
Stahl-Timmins, W., Depledge, M.H., Flemming, L.
and Benedict, B.W., 2012, 'Paradigmatic approaches
to studying environmental and human health:
Late lessons from early warnings: science, precaution, innovation
681
Implications for science and governance | In conclusion
(Forgotten) Implications for interdisciplinary
research', Environmental Science and Policy, (25)
January 2013, 218–228.
Puma, 2011, PUMA's Environmental Profit and Loss
Account for the year ended 31 December 2010, (http://
about.puma.com/wp-content/themes/aboutPUMA_
theme/financial-report/pdf/EPL080212final.pdf).
Rodercick, P., 2010, Taking the longer view: UK
governance options for a finite planet, Foundation
for Democracy and Sustainable development and
Worldwide Fund for Nature, London.
RMNO, 2009, Sustainable development and the
Governance of Long-term Decisions. EEAC Working
Group Governance, Louis Meuleman and Roeland J.
in 't Veld.
Santayana, G. 1905, Reason in Common Sense, the first
volume of Santayana's five-volume Life of Reason.
Charles Scribner's Sons, page 284.
SCENIHR, 2012, Memorandum on the use of the
scientific literature for human health risk assessment
purposes – weighing of evidence and expression of
uncertainty, Scientific Committee on Emerging
and Newly Identified Health Risks, European
Commission, Brussels.
682
Stirling, A., 2010, 'Keep it complex', Nature, 468,
1 029–1 031.
UCS, 2012, Heads They Win, Tails We Lose. How
Corporations Corrupt Science at the Public's Expense,
Union of Concerned Scientists, Cambridge, Mass.,
USA.
UN, 2012, System of Environmental-Economic
Accounting Central Framework, United Nations
Statistics Division, New York, (http://unstats.un.org/
unsd/envaccounting/White_cover.pdf)
Van den Hove, S., McGlade, J., Mottet, P. and
Depledge, M.H., 2012, The Innovation Union:
A perfect means to confused ends? Environmental
Science and Policy, (12/1) 73–80.
Ward, H., 2012, The future of democracy in the face
of climate change, Foundation for Democracy and
Sustaiable Development, London.
WBCSD, 2010, Vision 2050, World Business Council
for Sustainable Development, Geneva.
WBGU,2012, Towards Low Carbon Prosperity: national
strategies and International Partnerships, German
Advisory Council on Global Change, International
Symposium, 9th May, Berlin
Stirling, A. 2007, A general framework for analysing
diversity in science, technology and society. J. R. Soc.
Interface, (22/4/15) 707–719.
WEF, 2012. Global risks 2012: insight report. An
initiative of the Risk Response Network. 7th edition.
World Economic Forum, Geneva.
Stirling, A., 2008, '"Opening up" and "closing down"
— power, participation, and pluralism in the social
appraisal of technology', Science, Technology and
Human Values, (33/2) 262–294.
Weiss C, 2002, Scientific uncertainty in advising and
advocacy, Technology in Society, (24/4) 375–386.
Late lessons from early warnings: science, precaution, innovation
kobosnicAccessControl.interfaces.IRoleManagerAcquisition.interfaces.IAcquirerProducts.CMFDynamicViewFTI.interfaces.ISelectableBrowserDefaultApp.interfaces.IUndoSupportOFS.interfaces.IItemProducts.NavigationManager.sections.interfaces.INavigationSectionPositionableplone.locking.interfaces.ITTWLockableAccessControl.interfaces.IOwnedplone.app.blob.interfaces.IATBlobFileProducts.ATContentTypes.interfaces.file.IFileContentplone.uuid.interfaces.IUUIDAwareeea.pdf.subtypes.interfaces.IPDFAwareeea.epub.subtypes.interfaces.IEPUBAwareProducts.CMFCore.interfaces._content.IWorkflowAwareProducts.Archetypes.interfaces.metadata.IExtensibleMetadataarchetypes.schemaextender.interfaces.IExtensiblewebdav.EtagSupport.EtagBaseInterfaceOFS.interfaces.IPropertyManagereea.cache.subtypes.interfaces.ICacheAwareProducts.CMFCore.interfaces._content.IContentishplone.app.blob.interfaces.IATBlobeea.themecentre.interfaces.IThemeTaggableOFS.interfaces.ICopySourceplone.app.imaging.interfaces.IBaseObjecteea.alchemy.interfaces.IAlchemyDiscoverableeea.app.visualization.subtypes.interfaces.IPossibleVisualizationApp.interfaces.IPersistentExtraProducts.CMFCore.interfaces._content.IOpaqueItemManagerpersistent.interfaces.IPersistentwebdav.interfaces.IWriteLockeea.geotags.storage.interfaces.IGeoTaggableplone.app.iterate.interfaces.IIterateAwareeea.relations.content.interfaces.IBaseObjectProducts.ATContentTypes.interfaces.file.IATFileOFS.interfaces.ISimpleItemProducts.Archetypes.interfaces.referenceable.IReferenceableProducts.CMFCore.interfaces._content.IDynamicTypeProducts.Archetypes.interfaces.base.IBaseContentProducts.Archetypes.interfaces.base.IBaseObjecteea.progressbar.interfaces.IBaseObjectProducts.CMFCore.interfaces._content.ICatalogAwareOFS.interfaces.ITraversableeea.versions.interfaces.IVersionEnhancedeea.annotator.subtypes.interfaces.IAnnotatorAwareProducts.LinguaPlone.interfaces.ITranslatableeea.workflow.interfaces.IHasMandatoryWorkflowFieldsAccessControl.interfaces.IPermissionMappingSupportProducts.ATContentTypes.interfaces.interfaces.IATContentTypeplone.portlets.interfaces.ILocalPortletAssignableeea.promotion.interfaces.IPromotablewebdav.interfaces.IDAVResourceLate lessons from early warnings II - In conclusion42013-05-27T10:22:22Zlate-lessons-ii-chapter-282013-01-30T10:10:00Z