Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Applications

Approved:

IHC

Immunofluorescence

Western blot

ELISA

Specificity and Use

Immunogen:

Human erythrocytes L-Lactic dehydrogenase LDH-2(H3M) isozyme

Specificity:

Human LDH / Lactate Dehydrogenase. The reagents were evaluated for potency, purity and specificity using most or all of the following techniques: immunoelectrophoresis, cross-immunoelectrophoresis, single radial immunodiffusion (Ouchterlony), block titration, ELISA, immunoblotting and enzyme inhibition. Cross-reactivity Cross-reactivities against enzymes of other sources may occur but have not been determined.

Usage:

This product is intended for use in precipitating and non-precipitating antibody-binding assays (such as e. g., ELISA and Western blotting and immunofluorescence or histochemical techniques). The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

Presentation:

Lyophilized from PBS, pH 7.2

Reconstitution:

1,000 µl Sterile distilled water 1 ml

Storage:

Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.

Restrictions:

For research use only.

About LDH / Lactate Dehydrogenase

Description: Lactate dehydrogenase is composed of four subunits (tetramer). The two most common subunits are the LDH-M and LDH-H protein, encoded by the LDHA and LDHB genes, respectively. These two subunits can form five possible tetramers (isoenzymes): 4H, 4M, and the three mixed tetramers (3H1M, 2H2M, 1H3M).