Before launching into the song, Timberlake told the crowd, “Sometimes in life, you think you found the one. But then one day you find out that she is just some b–!”

The comment sparked outrage among Spears’ fans on Twitter, with many followers taking aim at Timberlake over his quip.

The star decided to quell the anger by taking to the social networking website to deny his remark was aimed at the pop star, writing, “Ok. I see you. Wouldn’t disrespect ANYONE personally. Ever. Relax…”