I have set up ispconfig3 + django + mod_wsgi and have gotten it to run in a vhost just fine for me. Of course, it very well might not work for anyone else and there are no stated or implied guarantees this will work.

Next:
open and edit the settings.py file and add your DB information and other settings and save the file.

Next: (note you can use your own names here)
cd into the .wsgi directory and create a file inside that dir called django.wsgi This will be your mod_wsgi configuration file that will be referenced in your apache config. The names of both the dir and file are up to you be remember to change them in the following options and wsgi files.

Open and edit your .wsgi and add the following (making sure to change the paths to your server specs)