Larry Wilmore returned from a two-week break to take aim at Bill Cosby’s admission that he drugged women for sex.

The “Nightly Show” host aired portions of a 1969 comedy routine by Cosby, who joked that he wanted to slip women the “Spanish fly” aphrodisiac.

“Go to a party and see five girls standing alone,” Cosby said. “Boy, if I had a whole jug of Spanish fly, I’d light that whole corner up over there.”

The audience reacted in horror and disgust, and Wilmore pointed out that the routine was recorded 15 years before “The Cosby Show” aired — and then he showed another disturbing example from that NBC sitcom that revealed the comedian’s fascination with drugging women for sex.

Cosby explained to his wife on the show that people who eat his barbecue sauce become “huggy-buggy” afterward, as his TV daughter and son-in-law nuzzle one another.

“Jesus Christ, Sondra can’t even keep her eyes open,” Wilmore said.

Wilmore explained that he referred to the beloved comic and actor as a “motherf*cker” because he was “a horrible human being.”

“He believes that drugging and raping women deserves to be laughed at,” Wilmore said. “He put it in a comedy act, and he put it in his TV show. He finds what he did to be funny. Five words: You can go f*ck yourself.”