Fusion

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Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RSAG_00398

MATE efflux family protein (451 aa)

Predicted Functional Partners:

RSAG_00399

Uncharacterized protein (302 aa)

0.729

RSAG_01887

Uncharacterized protein (369 aa)

0.558

RSAG_03284

1-acyl-sn-glycerol-3-phosphate acyltransferase (237 aa)

0.546

RSAG_03133

1-acyl-sn-glycerol-3-phosphate acyltransferase (248 aa)

0.546

RSAG_00397

Uncharacterized protein (205 aa)

0.541

RSAG_00673

MATE efflux family protein (446 aa)

0.488

RSAG_03244

Single-stranded DNA-binding protein (153 aa)

0.469

RSAG_02221

Uncharacterized protein (208 aa)

0.469

infB

Translation initiation factor IF-2 ; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (941 aa)

0.447

rbfA

Ribosome-binding factor A ; Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5’-terminal helix region of 16S rRNA (131 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

RSAG_00397

RSAG_00398

RSAG_00397

RSAG_00398

Uncharacterized protein

MATE efflux family protein

0.541

RSAG_00397

RSAG_00399

RSAG_00397

RSAG_00399

Uncharacterized protein

Uncharacterized protein

0.423

RSAG_00398

RSAG_00397

RSAG_00398

RSAG_00397

MATE efflux family protein

Uncharacterized protein

0.541

RSAG_00398

RSAG_00399

RSAG_00398

RSAG_00399

MATE efflux family protein

Uncharacterized protein

0.729

RSAG_00398

RSAG_00673

RSAG_00398

RSAG_00673

MATE efflux family protein

MATE efflux family protein

0.488

RSAG_00398

RSAG_01887

RSAG_00398

RSAG_01887

MATE efflux family protein

Uncharacterized protein

0.558

RSAG_00398

RSAG_02221

RSAG_00398

RSAG_02221

MATE efflux family protein

Uncharacterized protein

0.469

RSAG_00398

RSAG_03133

RSAG_00398

RSAG_03133

MATE efflux family protein

1-acyl-sn-glycerol-3-phosphate acyltransferase

0.546

RSAG_00398

RSAG_03244

RSAG_00398

RSAG_03244

MATE efflux family protein

Single-stranded DNA-binding protein

0.469

RSAG_00398

RSAG_03284

RSAG_00398

RSAG_03284

MATE efflux family protein

1-acyl-sn-glycerol-3-phosphate acyltransferase

0.546

RSAG_00398

infB

RSAG_00398

RSAG_03044

MATE efflux family protein

Translation initiation factor IF-2 ; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex

0.447

RSAG_00398

rbfA

RSAG_00398

RSAG_03043

MATE efflux family protein

Ribosome-binding factor A ; Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5’-terminal helix region of 16S rRNA

0.447

RSAG_00399

RSAG_00397

RSAG_00399

RSAG_00397

Uncharacterized protein

Uncharacterized protein

0.423

RSAG_00399

RSAG_00398

RSAG_00399

RSAG_00398

Uncharacterized protein

MATE efflux family protein

0.729

RSAG_00673

RSAG_00398

RSAG_00673

RSAG_00398

MATE efflux family protein

MATE efflux family protein

0.488

RSAG_00673

RSAG_02221

RSAG_00673

RSAG_02221

MATE efflux family protein

Uncharacterized protein

0.469

RSAG_00673

RSAG_03133

RSAG_00673

RSAG_03133

MATE efflux family protein

1-acyl-sn-glycerol-3-phosphate acyltransferase

0.546

RSAG_00673

RSAG_03244

RSAG_00673

RSAG_03244

MATE efflux family protein

Single-stranded DNA-binding protein

0.469

RSAG_00673

RSAG_03284

RSAG_00673

RSAG_03284

MATE efflux family protein

1-acyl-sn-glycerol-3-phosphate acyltransferase

0.546

RSAG_00673

infB

RSAG_00673

RSAG_03044

MATE efflux family protein

Translation initiation factor IF-2 ; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex

0.447

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: