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Theresa May has been urged to isolate “hardline Eurosceptics” and deliver a Brexit deal capable of uniting pro-European Tory and Labour MPs.

Ken Clarke, the Tory former chancellor, said the “maths makes it obvious” that the only way for the Prime Minister to get an agreement through the House of Commons would be to unite Europhile MPs.

But Mrs May said she hoped “everybody across this whole House will put the national interest first” when it comes to voting on her deal as she said MPs had a “duty” to deliver on the result of the 2016 EU referendum.

Mr Clarke’s intervention came as pressure continued to grow on Mrs May to ditch her Chequers plan for Brexit and as talks entered a critical phase...