High intensity focussed ultrasound (HIFU) is
increasingly being used to treat locally recurrent prostate cancer that has
failed primary treatment. Nine patients were studied using a 1.5T Intera MR
scanner with an endorectal receiver coil, before, after 6 weeks and after 6
months of HIFU treatment. Standard and diffusion-weighted images were acquired.
ADCs and volumes for the whole gland were obtained for all time points. The
results are suggesting that ADC at 6 weeks is an indicator of subsequent
reduction in PSA. Earlier time points for measuring ADC may prove useful in
predicting subsequent outcome and warrant further investigation.