WASHINGTON — Minnesota Sen. Al Franken said Thursday he will resign from Congress in coming weeks following a wave of sexual misconduct allegations and a collapse of support from his Democratic colleagues, a swift political fall for a once-rising Democratic star.

“I may be resigning my seat, but I am not giving up my voice,” Franken said in the otherwise-hushed Senate chamber.

Franken quit just a day after new allegations brought the number of women alleging misconduct by him to at least eight.

Wednesday morning, one woman said he forcibly tried to kiss her in 2006, an accusation he vehemently denied.

Hours later, another woman said Franken inappropriately squeezed “a handful of flesh” on her waist while posing for a photo with her in 2009.

“I know in my heart that nothing I have done as a senator — nothing — has brought dishonor on this institution,” Franken declared Thursday.

Franken, the former comedian who made his name on “Saturday Night Live,” had originally sought to remain in the Senate and cooperate with an ethics investigation, saying he would work to regain the trust of Minnesotans.

“Some of the allegations against me are simply not true,” Franken said Thursday. “Others I remember quite differently.”

Still, he said he could not both cooperate with an investigation and fully carry out his duties to his constituents.

Franken had gained respect as a serious lawmaker in recent years and has even been mentioned in talk about the 2020 presidential campaign.

His resignation means Minnesota Gov. Mark Dayton, a fellow Democrat, will name a temporary replacement.

The winner of a special election in November would serve through the end of Franken’s term in January of 2021. Among the possibilities is Lt. Gov. Tina Smith, a trusted ally.

“Enough is enough,” Sen. Kirsten Gillibrand of New York declared on Wednesday. “We need to draw a line in the sand and say none of it is OK, none of it is acceptable, and we, as elected leaders, should absolutely be held to a higher standard.”

A torrent of Democrats quickly followed Gillibrand.

“I’m shocked and appalled by Sen. Franken’s behavior,” said Sen. Patty Murray of Washington state. “It’s clear to me that this has been a deeply harmful, persistent problem and a clear pattern over a long period of time. It’s time for him to step aside.”

Franken has acknowledged and apologized for some inappropriate behavior, but he strongly denies the new accusation that came from a former Democratic congressional aide, who said he tried to forcibly kiss her after a taping of his radio show in 2006.

The woman, who was not identified, told Politico that she ducked to avoid his lips but Franken told her: “It’s my right as an entertainer.”

Franken said the idea he would claim such conduct as a right was “preposterous.”