2. Diethylstilbestrol (DES) -- Maker: Multiple manufacturersRecalled: 1975 (after 37 years on the market)Financial damage: Steep, but difficult to quantify because each manufacturer paid out legal damages correlated with its respective market share

1. Fenfluramine/phentermine (Fen-Phen) -- Maker: Wyeth-Ayerst LaboratoriesRecalled: 1997 (after 24 years on the market)Financial damage: Awards to victims close to $14 billion, making it one of the most costly products liability cases in history

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