School of Medicine

Showing 1-49 of 49 Results

Bio
Ross graduated from Case Western Reserve University in Cleveland Ohio in 2007 with a B.S. in Physics (with a concentration in Biophysics) and a minor in Mathematics. He followed on to complete his Ph.D. in the Physiology and Biophysics department at CWRU in 2014 in the laboratory of Dr. Ben Strowbridge studying the role of subthreshold oscillations and persistent activity in the rodent hippocampus, a region of the brain thought to be responsible for short term memory and spatial navigation. He then did postdoctoral research in the laboratory of Dr. Cameron McIntyre developing computational models of evoked activity in the motor cortex in response to deep brain stimulation and now is excited to be moving full circle as an electrophysiologist to be developing new technology and therapeutic biomarkers for the treatment of Parkinson's Disease through deep brain stimulation. Outside of the lab, Ross enjoys the great Bay Area outdoors through swimming, running, biking and hiking as well as tinkering with model steam engines, amateur electrics, and printed circuit boards.

Bio
Tanusree studied Biomedical Sciences from Delhi University, and obtained her PhD in Neuroscience from National Brain Research Center in India. Her doctorate work established distinct cortical reading networks for Hindi-English bilingual readers. Thereafter she went to University of Texas Southwestern, wherein she worked towards understanding memory deficits in patients with Schizophrenia. Currently at Stanford, she is studying hippocampal dysfunction and memory deficits in patients with Parkinson?s disease.

Bio
Christian received his Bachelor?s Degree at the University of California, Berkeley, where he developed his initial interest in functional brain imaging at the Helen Wills Neuroscience Institute with the D?Esposito Lab. He later attended the University of Wisconsin-Madison for his graduate studies and obtained his Doctorate Degree in the Neurosciences focusing on frequency analysis of the intrinsic low-frequency oscillation of the resting-state in populations of aging and ischemic stroke using rs-fMRI.

Currently, Christian is interested in the characterization of cortical system disruption in Parkinson?s disease population, in terms of functional network interactions and dynamics of the network connectivity.

Bio
After receiving my Bachelors (2006) and Masters (2010) degrees at the University of Wisconsin ? Milwaukee, I obtained my PhD at Southern Illinois University in 2013. My current research focuses on the central nervous systems response to insult.

I am interested in understanding the complex cellular and molecular interactions that comprise the neuroinflammatory response to neural injury in an effort to develop therapeutic treatment options that produce the most optimal response to multiple types of neural insult and other neurobiological disorders. The World Health Organization reports that neurological disorders are one of the greatest threats to public health. Of the hundreds of these disorders, some of the most common are traumatic brain injury, stroke, and degenerative disorders. Although these disorders are initiated through different causes, the common underlying factor in all of these neurodegenerative diseases is neuroinflammation. The acute response is characterized by glial cell activation, oxidative stress, and edema, all of which lead to increased tissue damage. Chronic neuroinflammation is a sustained, self-perpetuating response that persists long after the onset of neural insult. There is a complex interaction between resident immune cells like microglia and astrocytes and infiltrating immune cells including neutrophils, macrophages, and T lymphocytes. This complicated response to neural injury is a defense mechanism to remove harmful agents and promote recovery, but when over active, it can contribute to further damage. My current objective is to identify the underlying mechanisms of the neuroinflammatory response in multiple different animal models of injury and neurobiological disorders. Ultimately my goal is to steer a group that is running preclinical trials on cellular and molecular compounds designed to reduce the harmful features of the neuroinflammatory response but to harness the beneficial aspects.

Bio
Professional Summary: Hanadie Yousef is a trained neurobiologist and stem cell biologist with a focus on the mechanisms of aging, with pending and issued patents, several publications, a PhD from Berkeley, a 4-year postdoc at Stanford, experience leading research teams, and has worked in R&D at Regeneron and Genentech.

In graduate school, Yousef studied the role of adult stem cells in the biology of aging and developed methods for tissue rejuvenation in brain and muscle. Her current research in the Wyss-Coray lab lies in understanding the molecular and cellular mechanisms that contribute to both a decline in brain function with aging and the onset of neurodegenerative diseases, with a focus on understanding the interactions between aged blood and the blood-brain barrier.

Education and Research Training: Hanadie Yousef earned her bachelors in Chemistry with honors and a minor in Spanish from Carnegie Mellon University (CMU) in 2008 and went on to obtain a Ph.D. in Molecular and Cell Biology at the University of California, Berkeley in 2013. Since April 2014 she has been a postdoctoral fellow in the Neurology department at Stanford University School of Medicine.

Undergraduate Research: Yousef began doing biomedical research in high school, where she interned locally at a pharmaceutical company in New York, Regeneron, to do research on gene therapy and cancer. She presented her research in local and international science competitions and symposiums. She returned to Regeneron to continue her research during winter and summer internships for 5 years (2003-2008). During her undergraduate studies at CMU, Yousef did a research honors thesis at University of Pittsburgh Medical Center, where she elucidated molecular mechanisms driving idiopathic pulmonary lung fibrosis (2 co-authorship studies, 1 invention disclosure).

Dissertation Research: Yousef studied the role of adult stem cells in the biology of aging and developed methods for tissue rejuvenation in brain and muscle (4, 1st author publications, 1 issued patent, 1 pending). During the last year of her graduate studies (2013), she did a summer internship at Genentech in the neurodegeneration group of R&D, where she studied inflammatory mechanisms underlying neurodegeneration.

Postdoctoral Research: Yousef?s current research focus in the Wyss-Coray lab lies in understanding the molecular and cellular mechanisms that contribute to both a decline in brain function with aging and the onset of neurodegenerative diseases. She has a manuscript in review, a pending patent, and a translational research grant through the Stanford SPARK program based on her discoveries.

Hanadie has gotten many awards and honors along the way in pursuing her passion in translational scientific research, including the National Science Foundation graduate research fellowship (2009-2012), the NRSA F32 postdoctoral fellowship (2016-ongoing), a Stanford Spark grant (2017), presentation and poster awards, and travel and training scholarships at local and international scientific conferences and research institutions. Yousef has presented her research and given lectures across the globe, receiving attention in local, university and international media outlets. Yousef has a strong passion for teaching and mentorship. She was an Instructor for Drug Discovery at UCSC during the first 2 years of her postdoctoral training and has advised many undergraduate students during her graduate and postdoctoral research training, including 3 who received research honors theses under her tutelage. Yousef has several publications and issued and pending patents on methods for tissue rejuvenation.