The same painting, completed by Peter, shows the figure standing over Jackie's brainless corpse with red paint dripping from the canvas. The body was once thought to be Claire's, referencing the message, "Save the Cheerleader, Save the World".

Several paintings assemble to form a comic book page with a panel missing.

Other paintings first appeared in the online archives, but subsequently appeared in an episode. These include the painting of Claire's autopsy, the painting of Nathan as president, the painting of Niki and Jessica's reflection, and the painting of Mr. Bennet.

Trivia

Isaac's paintings as seen on screen are produced for the show by comic book artist Tim Sale. Because he is colorblind, Tim illustrates his images with black ink, sometimes diluted for greytones. The drawings are then digitally scanned at 11" x 17", colorized by Dave Stewart, and then manipulated to make them appear as if they were painted. The finished product is then blown up and printed on canvas.

The exception to this process is the painting of the explosion on the studio's floor. In an interview, Tim said "it's one of the few that there’s no wash, it's just strictly black-and-white. The original is about 10"-by-15", and I created three or four different versions of it. For the pilot, they blew it up in black-and-white first. Before the pilot aired, they went in and colored it digitally on the film." He also elaborated that it's not a painting on the floor. Instead, "What they did was reproduce it on a sort of large rubberized mat that they placed down on the floor. They’ve replaced it at least once. It’s a different image based on mine, and it was actually colored in originally. I guess that’s because they didn’t want to go back in and color it (in post-production) every time."

Most of Isaac's paintings are in reality colored by the comic book colorist Dave Stewart. A few paintings (the Eclipse painting, the Bus Explosion painting, and the Hand Holding Water Glass painting) were colored by propsmaster Burk Sauls.

In a forum post, Tim Sale said that oftentimes, a lot of his art "sits around for weeks waiting to be used." At other times, the whole process — from assignment to execution to color to scanning to printing and stretching the canvas to filming — is less than a week (though the production staff tries to avoid a rushed pace).

Because the details of the scene (including the director, the wardrobe, the actor) had not yet been definitely determined when the painting of Mohinder in the river was created, Tim Sale said that he decided to focus more on the mood of the painting than on the details.

In a forum post, Tim Sale said he gave the production staff his personal sketchbook, and thought they would return it to him as soon as they gleaned what they needed. He was surprised when they made larger copies of the sketches and pasted them into a new sketchbook to be used as a prop.

Tim Sale said that the sketch of Peter and Simone kissing was made using charcoal pencil, some wash, and colored ink. In an interview, Tim Sale said that he is not great at likenesses, so when it came time to create the sketch, he told producer Jeph Loeb, "Maybe I'll Eisner it." It was determined that rather than perfect likenesses, the important thing to get across was the mood, the red umbrella, and to see that it is two people being intimate with each other. Incidentally, Jeph's daughter, Audrey, asked to get the sketch, so Tim gave it to her as a gift.

Tim Sale has said that he is particularly proud of the painting of the train wreck and the painting of Claire being chased by a shadow. His least favorite is the painting of Peterflying, because he thinks "it’s kind of a sissy drawing" and "it looks silly." He also said "it has this pansy quality to it that bugs me". In fact, the only part of the painting Tim liked was the coat.

Originally, the painting of the explosion that is painted on the floor of Isaac's loft was in black and white. In the commentary for the unaired pilot, Tim Kring said that it was colored by the promotional department to promote the show. The crew liked the look of the colored floor mural so much that they continued to colorize it in post production so it would match the promotional department's work. After a few episodes, the process became so tedious that that they decided to just color the actual floor.