Supercomputing the Resistome

September 14, 2012 | Nobel laureate Bruce Beutler is using the supercomputing resources at the Texas Advanced Computing Center (TACC) at The University of Texas at Austin to sequence the exomes of 8.000 mice—48 exomes each week. The goal: identify the key genes required to resist infection—the so-called mammalian "resistome"—and to determine how these genes interact with one another to defend the body (or in the case of auto-immune diseases, set the body against itself). TACC