that file have no trojan , if you scan it with different antivirus you will get different results for each one of them . dont believe in everything antivirus says or you will no be able to install anything on your computer .
That files is from assassins creed 3 reloaded release patch , it have no trojan or what so ever .
every patch made by crackers for games if you scan the files with antivirus it will say that is infected , but it can not be taken seriously .
If you still dont want to use it then you can always put a ticket on ubisoft technical support and wait for a reply .

Greeting!
I solved the problem I ran Far Cry 3 on windows xp 3.Good work, I am satisfied.
I hope it will be helpful.
Fix for application failed to initialize properly (0xc0000142) error :
Go to gamecopyworld and download the "fixed" files for Assassin's Creed III. inside you will see a file called ubiorbitapi_r2_loader.dll and orbit_api.ini. Copy these 2 files and paste them into the "Farcry 3bin" folder and boom. Game works and runs and saves fine. Granted that you installed the directx and c++ runtime.

Do not copy uplay_r1_loader.dll into the folder as it will cause another error.

Everyone who gets the Application Error 0xc0000142
After I've stumbled on some guys who were trying to run Far Cry 3 with whine and ubuntu.
Just download Assassin's Creed III reloaded crack like from gamecopyworld it's the newest crack from ACIII.
Take the ubiorbitapi_r2_loader.dll from there and copy paste it over the Far Cry 3 reloaded crack.

Meaning you install the patch 1.01 or just let the game be updated from uplay, then copy AC3(reloaded) ubiorbitapi_r2_loader.dll and FC3(reloaded) FC3.dll, FC3_d3d11.dll, orbit_api, uplay_r1_loader.dll in "C:Program FilesUbisoftFarCry 3bin" folder.

i am getting this error on my win xp what i do ? http://s21.postimage.org/wvvtzv06f/untitled.jpg
I'm using the default shortcut from FC3Updater with -offline parameter on XP sp3 32bit(x86) also you might wanna increase the gpu buffer in options it seemed to fix the lag if you have any, I'm using gts 250 1gb, but still get decent fps at max settings on 1440x900.
Also my saves work, but I get sometimes some crashes when I'm going through the menu too fast, like split second decisions back and worth so it kinda goes freeze, happens maybe once per few hours, might be also memory issue.

can u please help me what i do ? i did everything like u said but then when i open the game it give me windows error "an unexpected error occured please close the game " this ,message so what i do now ?http://s21.postimage.org/wvvtzv06f/untitled.jpg