This study analyzes self-efficacy perceptions of prospective teachers towards teaching profession and their metacognitive awareness related to selecting teaching as a career. It was conducted with 781 prospective teachers. Self-efficacy perceptions of the participants were detected via the long form of Teachers’ Sense of Efficacy Scale (TSES) and their metacognitive awareness was determined by employing the long form of Metacognitive Awareness Inventory (MAI). The motives accounting for their selection of teaching as a career was explored through open-ended questions. It was detected that prospective teachers are at a rather sufficient level with respect to their general self-efficacy perception and its sub-dimensions and their metacognitive awareness is at rather high levels. At the end of the research, in general self-efficacy averages of prospective teachers, amongst all prospective teachers who answered that the profession was selected due to SSE (Student Selection Examination) result and the ones who selected it according to its suitability with his/her personality choice; in general metacognitive awareness averages amongst prospective teachers who answered that the profession was selected due to SSE (Student Selection Examination) result and its conformity with his/her ideal choice, love of children-nation-teaching choice and its suitability with his/her personality choice, a significant difference was detected in comparison with those prospective teachers who selected the profession according to SSE (Student Selection Examination) choice