-Yes, F**k it! That's you're answer for everything! (Big Lebowski) *really there are several that make their way into my everyday lexicon, but I can't pinpoint the ones I actually use in conversation.

-I'm surrounded by a**holes! (Spaceballs)

You know, I sat here for 10 minutes trying to think of more and I know there are literally hundreds, but I generally need a prompt of some kind to get one into conversation. But the top two are used primarily at work on a daily basis.

One of my favorite quotes my girlfriend and I use is off of Old School. When someone asks us about our plans for the weekend we'll say we "actually a pretty nice little Saturday, we're going to go to Home Depot. Yeah, buy some wallpaper, maybe get some flooring, stuff like that. Maybe Bed, Bath, & Beyond, I don't know, I don't know if we'll have enough time." It'll usually be some variation of it. But it's fun none the less.

We will quote various lines from Futurama also. There are so many great ones in that show.
"Good News Everyone" - Professor Fransworth
"I can't wait til I'm old enough to feel ways about stuff" - Fry
"Sweet Zombie Jesus" - Professor Fransworth
"With a warning label this big, you know they gotta be fun!" - Hermes

There are tons of others. The situation has to be right to break them out.

"this is insanity Max." " Or maybe it's GENIUS!" - Pi - between myself and another coworker when you have one of those ideas that is either complete garbage or pure gold, but you lack the perspective at the moment to tell.

"12:50, press return" - Pi - Pause in action, or when things feel overly structured, or at 12:50 if you are working through lunch

"Bueller, Bueller" - Ferris Bueller's Day Off - whenever there is no or little response from a question in a meeting