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1 Provincial Exam Questions Unit: Cell Biology: Protein Synthesis (B7 & B8) 2010 Jan 3. Describe the process of translation. (4 marks) 2009 Sample 8. What is the role of ribosomes in protein synthesis? A. to split the two strands of DNA apart B. to check for and replace the faulty codons C. to carry amino acids to the site of translation D. to provide a site for mrna and trna to join together 9. Give one role of each of the following nucleic acids in the production of an enzyme. DNA: mrna: rrna: trna: 10. Which of the following mutations will not result in the incorporation of the amino acid proline in a protein? A. a mutation of the DNA from GAA to GGA B. the use of a GGU anticodon during translation C. a substitution error changing the DNA from GGG to GGT D. the substitution of the first base in the DNA triplet for proline 1

2 2009 June 16. One structural difference between DNA and trna is that A. DNA has uracil and trna does not. B. trna contains more bases than DNA. C. DNA contains deoxyribose and trna does not. D. trna contains more hydrogen bonds than DNA. 17. Which of the following represents a molecule that contains peptide bonds? A. W B. X C. Y D. Z 2

3 18. Which of the following occurs if a mutation results in a codon changing from CGAto AGA? A. The resulting protein would be too short. B. The resulting protein would function correctly. C. The mrna would be repaired before leaving the nucleus. D. The resulting protein would contain serine in place of alanine. 19. Which of the following represents the base sequence of X after a single base mutation 3

4 has occurred? A. ATACGT B. ATTCGT C. AUACGU D. AUUCGU 20. Which of the following bonds have formed during this process? A. W and Y B. W and Z C. Y only D. Z only 2008 Aug 11. At which of the following does transcription occur? A. the vacuoles B. the ribosomes C. the Golgi bodies D. the chromosomes 12. Transcription and translation both result in molecules which A. contain deoxyribose. B. contain nitrogen atoms. C. have a tertiary structure. D. are produced in the cytoplasm. 4

5 13. What is the result of the translation of the DNA sequence CCGTATCTT? A. a dipeptide B. three amino acids connected by two peptide bonds C. three amino acids connected by three peptide bonds D. three amino acids connected by four peptide bonds 14. Mutations may be defined as changes in the A. arrangement of amino acids in nucleic acids. B. sequence of nitrogenous bases in nucleic acids. C. bonding occurring between bases in nucleic acids. D. structure of the DNA sugar-phosphate backbones Aug 5

6 14. Which of the following correctly describes this process? A. Translation is occurring in the nucleus. B. Replication is occurring in the nucleus. C. Transcription is occurring in the nucleus. D. Translation is occurring in the cytoplasm. 15. The sequence of bases in a portion of a DNA molecule is CCGTAC. Which of the following represents the sequence of bases in the corresponding codons? A. CCG TAC B. CCG UAC C. GGC ATG D. GGC AUG 16. Which DNA base sequence corresponds to the sequence of bases at X? 6

8 19. Which of the following examples of complementary base pairing occurs during translation? A. mrna bonds to DNA B. codons bond to codons C. adenine bonds to thymine D. anticodons bond to codons 20. What is a function of trna? A. to produce mrna B. to provide a location for translation C. to carry amino acids to the growing polypeptide chain D. to carry genetic information from the nucleus to the cytoplasm 2005 Aug 17. Which of the following is a step in transcription? A. Ribosomes move along mrna. B. Amino acids are joined by peptide bonds. C. Adenine in DNA bonds to thymine in mrna. D. Hydrogen bonds are broken to expose a section of the DNA helix. 18. The process shown includes which of the following steps? A. denaturing of trna B. codon-anticodon base pairing C. joining of adjacent nucleotides D. formation of hydrogen bonds between amino acids 8

9 19. Where in the cell does this process take place? A. the nucleus B. the nucleolus C. the Golgi bodies D. the rough endoplasmic reticulum 20. Ultraviolet light, which can alter DNA, is an example of which of the following? A. a mutagen B. polymerase C. an anticodon D. recombinant DNA 9

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