Giants wide receiver Odell Beckham Jr. will have ankle surgery this week, the team announced Monday.

Beckham, who suffered a fractured ankle in Sunday's loss to the Chargers, was placed on injured reserve Monday. Fellow wideout Dwayne Harris, who is also the team's primary kick returner, was also placed on IR with a fractured fifth metatarsal that will be surgically repaired on Tuesday.

The Giants are also expecting Brandon Marshall to miss multiple games with an ankle injury. He will undergo further testing this week. Also injuring an ankle in the 27-22 loss to the Chargers was wide receiver Sterling Shepard as the Giants experienced a day of receiver injuries that defied explanation.

Beckham suffered a fracture in his ankle in the fourth quarter of Sunday's loss as the Giants fell to 0-5 on the year. The 24-year-old had five catches for 97 yards including a 48-yard touchdown catch at the time of the injury. Beckham has 25 receptions for 302 yards and three touchdowns on the season.

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Giants coach Ben McAdoo said Monday he spoke with Beckham and referred to his injury as a "sad situation." The Giants added Tavarres King and Travis Rudolph to replace Beckham and Harris on the active roster.

"Next man up," McAdoo said. "They’re well-deserving of opportunities. You hate to see it like this, but it’s a part of the game."