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Open the front of the printer, cartritge should locate on its own to a position directly in front of you,printer must be switched on.When carriage stops plase your finger on top of the cartridge and press down,firmly,and pull towards you.it is easy!

Ink Cartridges for the HP C4280 has a microchip on the cartridge itself that turns off the printing after it runs out of ink. You must purchase a new HP 75 cartridge only from HP. A way to out smart HP is to purchase a different printer made by a differnet manufacture, but be aware they also may be using the onetime microchip in their cartridges.

I have exactly the same problem with a Canon Pixma MP800, I have cleaned the rollers, changed the ink cartridges and reset the printer. It will print a few pages cleanly then dump black ink on the roller which leaves a heavy black line on the back of the page. It fades away after printing about 10 pages and then a few pages later appears again. The printer is two years old and it looks as if I must buy another. Should I buy another Canon?

I just did it a few minutes ago and it's pretty simple. Just grab the thing right in the center, above the print tray (there's a little handle) and pull the top up. The ink carts will be right in there (towards you, on the right) just pull the one you need to replace out, directly towards you, and then pop the new one in. There are little notches on it so you can't put it in backwards/upside-down or anything, and there's no latch or anything physically holding the cartridges down