Associations

Radiographic features

Klinefeltersyndrome should be suspected in postpubertal males with bilateral symmetrical small testicular volume (usually 3~4 mL in volume) with ultrasonography, usually presented by subfertility/primary infertility or assessment of small testicular size and karyotyping should be recommended 7. However, Klinefelter syndrome is often overlooked or untreated.

Treatment and prognosis

Early recognition and hormonal treatment can improve quality of life and prevent serious complications. Testosterone replacement is mainly for androgen deficiency but does not improve infertility 7.