Warfarin News (14 articles)

A new anticoagulant called apixaban is superior to warfarin in preventing stroke with consistent effects across a wide range of stroke and bleeding risk in patients with atrial fibrillation, according to Duke University Medical Center researchers. Their results, published online in The...

A new study by medical scientists coordinated from the University of Manchester has for the first time used patients’ results to establish that “safety indicators” for people taking anticoagulant drugs to regulate a common heart condition are correct.More than 760,000 patients in the UK...

A large-scale trial finds that apixaban, a new anticoagulant drug, is superior to the standard drug warfarin for preventing stroke and systemic embolism in patients with atrial fibrillation. Moreover, apixaban results in substantially less bleeding and also results in lower...

Patients with irregular heart beats could benefit from a drug that is easier to administer than the current standard treatment.The condition, which is more common with older age and affects about 800,000 people in the UK, can lead to blood clots forming and significantly increases the risk of...

Approximately 250,000 Canadians are diagnosed with atrial fibrillation, a condition that causes the upper chambers of the heart to quiver and leads to an increased risk of stroke and complications of circulatory system.Oral blood thinners, such as warfarin and aspirin, are the only proven...

Researchers at Uppsala University, together with colleagues at the Karolinska Institute and the Sanger Institute, have now found all the genes the determine the dosage of the blood-thinning drug warfarin. The findings are published in the scientific journal PLoS Genetics."We have previously...

Genes determining the optimal dose of therapeutic warfarin have now been identified in a large-scale, genome-wide association scan (GWAS) of this pharmacogenetic trait. Researchers from the Wellcome Trust Sanger Institute, Uppsala University Hospital, and the Karolinska Institute have found...

Liverpool, UK - 20 February 2009: Scientists at the University of Liverpool have found that information about a patient's genes could help increase the effectiveness of drugs such as warfarin. A team of international researchers, which included scientists from Liverpool and...

Including genetic information in a patient's clinical profile might help determine the optimal starting dose of the common blood-thinner warfarin, according to findings from a large-scale study that will be published tomorrow, Thursday, February 19, in the New England Journal of...

• Warfarin dose related to two genes• Personalized medicine precursor: dose adjusted to patient's genetic makeup• UAB part of International Warfarin Pharmacogenetics ConsortiumBIRMINGHAM, Ala. - An individual's genetic makeup can have a profound effect on the required...

(Boston)- Researchers from Boston University School of Medicine (BUSM) have determined the optimal dose-management strategy to derive maximal benefit from warfarin therapy and improve patient outcomes. Results of the study appear online in the December 2008 issue of the Journal of Thrombosis and...