It is known that, in general, the air pollution concentrations have a close relationship with meteorological factors. The purpose of this study, examine the effect of meteorological factors on the daily SO2 and PM10 levels for the period 20082010. In this context identified research questions i. What is the temporal variation (monthly, annual, seasonal) of SO2 and PM10 from air pollution parameters in the Bilecik province? ii. Is there climatic conditions (air temperature, wind speed, humidity and pressure) impact on air quality parameters (SO2 and PM10) ? To answer these research questions, daily air pollution data (SO2 and PM10) and meteorological conditions (air temperature, wind speed, humidity, pressure) data for the period 2008-2010 were analayzed. The relationship between elements that cause air pollution with climatic elements such as temperature, wind speed, humidity and pressure, was analyzed using statistical methods. According to the results obtained through multiple linear regression analysis, for some months there is a moderate and weak level of relation between the SO2 and PM10 levels and the meteorological factors city. Both air pollution parameters were declined during the study perriods. This is despite the decrease was determined still above in the long-term limit values of PM.