BioPAX pathway converted from "PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA" in the Reactome database.2.6.1.52PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPAPXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA3-phosphonooxypyruvic acid + L-glutamate = O-phospho-L-serine + 2-oxoglutarateThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>Reactome DB_ID: 9773291cytosolGO00058293-phosphonooxypyruvic acid [ChEBI:30933]3-phosphonooxypyruvic acidReactomehttp://www.reactome.orgChEBI30933Reactome DB_ID: 294041L-glutamate(1-) [ChEBI:29985]L-glutamate(1-)C5H8NO4WHUUTDBJXJRKMK-VKHMYHEASA-M(2S)-2-ammoniopentanedioate146.12136L-glutamatehydrogen L-glutamateInChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1/t3-/m0/s1L-glutamic acid, ion(1-)[NH3+][C@@H](CCC([O-])=O)C([O-])=OL-glutamic acid monoanionChEBI29985Reactome DB_ID: 9367061O-phospho-L-serine [ChEBI:15811]O-phospho-L-serineChEBI15811Reactome DB_ID: 2940612-oxoglutarate(2-) [ChEBI:16810]2-oxoglutarate(2-)2-ketoglutaratealpha-ketoglutarate2-oxopentanedioic acid, ion(2-)2-oxoglutarateChEBI16810PHYSIOL-LEFT-TO-RIGHTACTIVATIONReactome DB_ID: 10554449PXLP-K200-PSAT1 dimer [cytosol]PXLP-K200-PSAT1 dimerReactome DB_ID: 105544472UniProt:Q9VAN0Drosophila melanogasterNCBI Taxonomy7227UniProtQ9VAN0N6-pyridoxal phosphate-L-lysine at 200 (in Homo sapiens)200EQUALN6-pyridoxal phosphate-L-lysine [MOD:00128]Chain Coordinates1EQUAL370EQUALReactome Database ID Release 7210554449Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10554449ReactomeR-DME-9773451Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-977345.1GO0004648GO molecular functionReactome Database ID Release 7210554450Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10554450Reactome Database ID Release 7210554452Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=10554452ReactomeR-DME-9773331Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-977333.1The amino group needed for serine biosynthesis comes from glutamate (L-Glu). Its transfer onto 3-phosphonooxpyruvate (3POPA) is catalysed by PSAT1 dimer which needs pyridoxal phosphate (PXLP) as cofactor. (Baek et al. 2003)12633500Pubmed2003Characterization of human phosphoserine aminotransferase involved in the phosphorylated pathway of L-serine biosynthesisBaek, JYJun, DYTaub, DKim, YHBiochem J 373:191-200inferred by electronic annotationIEAGOIEA