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You can lead a nanoparticle to tumor cells, but you can’t make them shrink—at least not until the particle gets inside.

This image shows biocompatible nanoparticles (yellow) inside clusters of pancreatic cancer cells (pink). The particles’ two-peptide uptake system—one to target the tumor, the second to penetrate it—was specially designed to overcome known difficulties in treating pancreatic cancer, but the Bhatia Lab hopes to expand the use of this modular delivery system for other cancer types as well.