Employing a range of approaches to address the physiological importance of the circadian:nuclear receptor system, ranging from population genetics, experimental medicine studies, CRISPR engineered mice, and cell biology.

Working closely with the craniofacial teams based in Oxford and other UK units, we specialise in the application of whole exome and genome sequencing to children born with a serious malformation of the skull termed craniosynostosis.

Several genes of the pro-inflammatory complement system, including CR1, Cr1L, Clu and C3 have been linked to AD. However, there remains a yawning gap in our understanding of how proteins derived from these genes impact risk of AD.

Squamous cell carcinomas (SCC) are amongst the most common cancer types afflicting man. SCCs most frequently arise from stratified squamous epithelia such as the epidermis or the mucosae of the head and neck.