Now, the Lexington-born actor is pledging his time to help those affected by Hurricane Harvey.

Clooney, along with a star-studded cast including Beyonce, Oprah Winfrey, Reese Witherspoon and Julia Roberts, next week will lead a telethon organized by Houston rapper Bun B and SB Projects' Scooter Braun to raise funds for those hit by the storm.

"Hand in Hand: A Benefit for Hurricane Harvey Relief," will air Sept. 12 at 8 p.m. on ABC, CBS, CMT, Fox and NBC, according to a news release. The telethon will also air on Facebook, Twitter and YouTube.

According to the release, proceeds from the telethon will benefit the United Way of Greater Houston, Habitat for Humanity, Save the Children, Direct Relief, Feeding Texas and The Mayor’s Fund for Hurricane Harvey Relief.

The one-hour broadcast will also feature appearances, performances, and taped tributes and messages from Jamie Foxx, Karlie Kloss, Matt Lauer, Rob Lowe, Matthew McConaughey, George Strait and a host of other stars, according to the release.

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Rescue crews save residents in Port Arthur, Texas on Sept. 1, 2017. As flood waters receded in Houston and residents began slowly returning home other nearby towns such as Rockport, Beaumont and Port Arthur were struggling to get back on their feet. Emily Kask, AFP/Getty Images

The Big Red Mud Truck rescue team helps flood victims off their truck in Port Arthur, Texas, Friday.
Storm-weary residents of Houston and other Texas cities began returning home to assess flood damage from Hurricane Harvey but officials warned the danger was far from over in parts of the battered state. Emily Kask, AFP/Getty Images

Galveston firefighters and emergency medical technicians transfer a Newborn Intensive Care Unit patient from an air ambulance Friday, Sept. 1, 2017, to a Galveston Emergency Medical Services ambulance at Scholes International Airport in Galveston, Texas. The infant, one of 11, was evacuated from a Beaumont hospital to the University of Texas Medical Branch after the East Texas city's water system failed during Tropical Storm Harvey. Jennifer Reynolds, AP