Tyro was the daughter of Salmoneus in Greek mythology, wife of Cretheus. She was the mother of the twins Pelias and Neleus, by Poseidon, and of Aeson, Pheres and Amythaon, by Cretheus.

Tyro married Cretheus, but she had fallen in love with Enipeus, a river god, who ignored her. One day, Poseidon, having lusted for Tyro, transformed into Enipeus and appeared in front of her. They slept together and as a result, Tyro became pregnant with the twin boys Pelias and Neleus. Tyro left her sons on a mountain to die, but they were rescued by a shepherd who raised them as his own. When the twins grew up, they found their mother and killed her stepmother Sidero, who mistreated Tyro. Afterwards, Tyro married Sisyphus, with whom he had two children. A prophecy said that these two children would kill their grandfather, Salmoneus, so Tyro killed them to save her father.