Humalog Mix

Humalog Mix Overview

Updated: January 9, 2015

Insulin lispro is a prescription medication used to treat type 1 and 2 diabetes. Insulin lispro is a fast-acting form of insulin. It is usually given with a long-acting insulin to provide a steady amount of insulin to control blood glucose (sugar) levels.

This medication comes in an injectable form available in vials and prefilled pens. Insulin lispro should be injected just under the skin, 15 minutes before or after meals.

Common side effects include low blood sugar, reaction at the injection site, and dizziness.

Get medical help right away if a serious allergic reaction (whole body reaction) occurs. A rash over your whole body, trouble breathing, a fast heartbeat, or sweating are all symptoms of a whole body reaction.

Reactions at the injection site (local allergic reaction) have occurred with insulin lispro injections. You may get redness, swelling, and itching at the injection site. If you keep having skin reactions or they are serious, talk to your healthcare provider. You may need to stop using insulin lispro and use a different insulin. Do not inject insulin to skin that is red, swollen or itchy.

Another possible side effect of insulin lispro injections is skin thickening or pits at the injection site (lipodystrophy). Change (rotate) when you inject your insulin to help to prevent these skin changes from happening. Do not inject insulin into this type of skin.

Humalog Mix Food Interactions

Follow dietary (food) recommendations made by your doctor and dietitian which should include a healthy diet. Skipping meals should be avoided as this can cause problems maintaining blood sugar control. There are no specific foods to avoid while using insulin lispro.

Inform MD

about all your medical conditions, including liver or kidney problems. Your dose may need to be adjusted.

if you are pregnant or breastfeeding. You and your healthcare provider should talk about the best way to manage your diabetes while you are pregnant or breastfeeding. Insulin lispro has not been studied in pregnant or nursing women.

about all the medicines you take, including prescription and non-prescription medicines, vitamins and herbal supplements. Your insulin lispro dose may need to change if you take other medicines.

Humalog Mix and Pregnancy

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Insulin lispro falls into category B. In animal studies, pregnant animals were given insulin lispro, and some babies had problems.

It is very important to maintain control of your blood sugar levels during pregnancy. Your doctor will decide which insulin is best for you during your pregnancy.

Humalog Mix and Lactation

It is not known if insulin lispro crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using insulin lispro.

Humalog Mix Usage

Insulin lispro can be used with a syringe, prefilled pen, reusable pen or external insulin pump. Talk to your doctor if you have any questions.

Read the instructions for use that comes with your insulin lispro product. Talk to your doctor if you have any questions. Your doctor should show you how to inject insulin lispro before you start taking it.

Insulin lispro is a rapid-acting insulin. You should take insulin lispro within fifteen minutes before eating or right after eating a meal.

Only use insulin lispro that is clear and colorless. If your insulin lispro is cloudy, colored, or has solid particles or clumps in it, return it to your pharmacy for a replacement.

Do not mix insulin lispro:

with any type of insulin other than NPH when used with injections by syringe.

how to make insulin lispro more dilute (that is, a smaller number of units of insulin lispro for a given amount of liquid) and

how to use this more dilute form of insulin lispro. Do not use dilute insulin in a pump.

Inject insulin lispro under your skin (subcutaneously) in your upper arm, abdomen (stomach area), thigh (upper leg), or buttocks. Never inject it into a vein or muscle. Change (rotate) your injection site with each dose.

If you have type 1 diabetes, you need to take a longer-acting insulin in addition to insulin lispro (except when using an external insulin pump).

If you have type 2 diabetes, you may be taking oral anti-diabetic medicines and/or a longer-acting insulin in addition to insulin lispro.

If you forget to take your dose of insulin lispro, your blood sugar may go too high (hyperglycemia). If high blood sugar is not treated it can lead to serious problems like loss of consciousness (passing out), coma or even death. Follow your doctor's instructions for treating high blood sugar.

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