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Beautifully Renovated Downtown Ocala FL Hotel in the heart of the Medical Community offers perfect midtown location Welcome to the Holiday Inn Express® Midtown Medical Center hotel in Ocala - US-441 (Midtown). Our hotel features like-home amenities professional services and a convenient downtown location directly across the street from Munroe Regional Medical Center and Ocala Regional Medical Center. With the State Attorney's Office E-One Lockheed Martin Cheney Brothers and other businesses just minutes away our hotel is perfect for business travelers. We also provide free high-speed Internet and a business center as well as a 703-square-foot meeting room that is perfect for your next meeting in Ocala. Located minutes off I-75 on US 441 we are just one mile from Downtown Square and the Historic District. Nearby attractions include the Appleton Museum Silver Springs Park Wild Waters College of Central Florida and Florida Fire College. The Ocala National Forest Canyon’s Zipline Tours and Santos Mountain Bike Trail are “must-do” outdoor adventures in the Ocala area. While staying at our hotel in Ocala join us each morning for our complimentary Express Start Breakfast Bar featuring a variety of delicious options. After a long day of work or sightseeing take a relaxing dip in the outdoor pool. We are pet-friendly. Make your reservations today!