As Warren's sultry character (also named Lesley) starts to panic and tries to leave -- she insists that she's feeling smoldering flames through her chest due to menopause -- she's called back by Lloyd's character, who dryly says, "Cool your bosom."

A distracted Shawn also tries to calm her down: "He's right. There is a storm raging, Lesley, and there is a hungry panther, and your bosom is full … and there are six of us, and there's only one rip."

Billy Lipps (played by Valentine), a onetime rock star who was jailed for murder, misunderstands Shawn's point and starts to tear off his pants.

Word also has it that this episode will include a Madeline Kahn shout-out; the comedian and "Clue" star died in 1999.

No doubt this will be one of "Psych's" most memorable pop culture-based episodes ever. "100 Clues" airs Wednesday, 3/27 at 10 PM on USA.