@article{Berghuis2005EndocannabinoidsRI,
title={Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor.},
author={Paul Berghuis and Marton Benedek Dobszay and Xinyu Wang and Sabrina M. Spano and Fernanda Ledda and Kyle Matthew Sousa and Gunnar Schulte and Patrik Ernfors and Ken Mackie and Gustavo Paratcha and Yasmin L Hurd and Tibor Harkany},
journal={Proceedings of the National Academy of Sciences of the United States of America},
year={2005},
volume={102 52},
pages={
19115-20
}
}

In utero exposure to Delta(9)-tetrahydrocannabinol (Delta(9)-THC), the active component from marijuana, induces cognitive deficits enduring into adulthood. Although changes in synaptic structure and plasticity may underlie Delta(9)-THC-induced cognitive impairments, the neuronal basis of Delta(9)-THC-related developmental deficits remains unknown. Using a Boyden chamber assay, we show that agonist stimulation of the CB(1) cannabinoid receptor (CB(1)R) on cholecystokinin-expressing interneurons… CONTINUE READING