Government Notices

Nearly Half of Prempro Lawsuits Settled by Pfizer

Date Published: Tuesday, December 20th, 2011

Of the 10,000 lawsuits filed against Pfizer over allegations that its menopause drug Prempro caused breast cancer, nearly half have been settled, as reported in a November filing with the Security Exchange Commission. The filing also stated that Pfizer had added $68 million to the $772 million it already reserved for resolution of the cases, Bloomberg has reported.

A reported 6 million women used Prempro to treat mood swings, hot flashes, and other symptoms of menopause before a 2002 study by the Women’s Health Initiative revealed a link to cancer. Prempro is a combination therapy of Wyeth’s Premarin, an estrogen-based drug, and Provera, a progestin-based drug made by Pfizer’s Upjohn unit.

Pfizer said in the filing that they “recorded a charge of $260 million in the first nine months of 2011 that provides for the minimum expected costs to resolve all remaining hormone-replacement actions.” The filing also stated that Pfizer had settled nearly 5,000 of the lawsuits.

Pfizer spokesperson Chris Loder said in an email statement that “Pfizer continues to have a strong record of success in defending these cases.” He also said, “While we will continue to look for opportunities to enter into favorable settlements where appropriate, we will also continue to vigorously defend these medicines in litigation,” Bloomberg reported.

Wyeth and Upjohn have currently lost 10 of the 18 Prempro cases decided by jury since 2006, including a Philadelphia trial in which the jury ordered the drug maker to pay $72.6 million in compensatory damages to three women who acquired breast cancer after using the hormone replacement therapy.

Nearly Half of Prempro Lawsuits Settled by Pfizer

Date Published: Tuesday, December 20th, 2011

Of the 10,000 lawsuits filed against Pfizer over allegations that its menopause drug Prempro caused breast cancer, nearly half have been settled, as reported in a November filing with the Security Exchange Commission. The filing also stated that Pfizer had added $68 million to the $772 million it already reserved for resolution of the cases, Bloomberg has reported.

A reported 6 million women used Prempro to treat mood swings, hot flashes, and other symptoms of menopause before a 2002 study by the Women’s Health Initiative revealed a link to cancer. Prempro is a combination therapy of Wyeth’s Premarin, an estrogen-based drug, and Provera, a progestin-based drug made by Pfizer’s Upjohn unit.

Pfizer said in the filing that they “recorded a charge of $260 million in the first nine months of 2011 that provides for the minimum expected costs to resolve all remaining hormone-replacement actions.” The filing also stated that Pfizer had settled nearly 5,000 of the lawsuits.

Pfizer spokesperson Chris Loder said in an email statement that “Pfizer continues to have a strong record of success in defending these cases.” He also said, “While we will continue to look for opportunities to enter into favorable settlements where appropriate, we will also continue to vigorously defend these medicines in litigation,” Bloomberg reported.

Wyeth and Upjohn have currently lost 10 of the 18 Prempro cases decided by jury since 2006, including a Philadelphia trial in which the jury ordered the drug maker to pay $72.6 million in compensatory damages to three women who acquired breast cancer after using the hormone replacement therapy.

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