Meanwhile, Kathy Griffin tweeted “FINALLY! Equality IS coming" in response to a follower asking her to talk about the news, and then tweeted another: "Reflecting on a historic weekend in fight for equality. Our national security & humanity will be stronger without #DADT."

There are three big couples in final contention for the most shocking split of 2010: Courteney Cox & David Arquette, Sandra Bullock & Jesse James, and the most recent one, Eva Longoria & Tony Parker!

I gotta say, I think that Sandra and Jesse's split was the most shocking because of the way it went down. I also thought they made a good couple, despite so many people saying that they never saw them together as a pair in the first place.

What do you think? Would you say Sandra and Jesse's break-up was the most shocking split of 2010? Post your comment below.

She’s known best as the creator of “Grey’s Anatomy,” which is in its seventh season and the spin-off, “Private Practice,” which is in its fourth. The writer/executive producer is also getting ready to reap in the rewards of her new drama, “Off the Map,” that premieres on January 12.

Adding to her royal duties will be a yet-untitled project for 2011 that ABC just gave her the go-ahead to produce.