Dr. Yee’s interests are in gene-nutrient interactions that affect the development and progression of breast cancer. In the laboratory she is investigating the mechanism(s) by which dietary fat content affects HER-2/neu signal transduction in mammary carcinogenesis. Dr. Yee’s research interests are closely tied to her clinical focus in breast cancer treatment and prevention, which allows for correlative tissue analyses, exploration of novel tissue biomarkers of breast risk and response to chemopreventive and/or bioactive nutrients, and clinical trial evaluation of specific dietary or nutrient interventions.