Unione Sportiva Cremonese is an Italian football club, based in Cremona. The club was founded in 1903. Cremonese played the 2005/2006 season in Serie B, having won and were therefore relegated to Serie C1 for 2006/07. It currently plays in Lega Pro Prima Divisione.

Their last appearance in Serie A was in 1996.

Cremonese won the Anglo-Italian Cup in 1992/93, beating English club Derby County in the final at Wembley Stadium.

Some of the famous players who played for Cremonese include Gianluca Vialli, Władysław Żmuda, Anders Limpar, Giuseppe Favalli, John Aloisi and Enrico Chiesa.