Responses (5)

I use to take Cymbalta and when I started it took about two weeks for me to feel less sad and gloomy. It is weird, its like you dont seem to notice it and then all of a sudden everything seems to be less of a big deal and things arent so stressful.Good luck friend!

on average its 4-6 weeks to show full effects. and i hope you did take ssri's before going on an snri. snri's like pristiq cymbalta and effexor have about a 11 hour half life (means 1/2 the meds are still in your system 11 hours after using) but ssri's half life are closer to 24 hours usualy (atleast zoloft is 26) which means if the SNRI doesnt work you have to be very carful not to miss a dose or you will feel withdrawls

I am on my third week in. And I wax and wane. The depression part seemed to ease up right away but the anxiety was been a roller coaster for me. I am on my 2nd week starting my 3rd on 60mg. I have been back to the doc twice because of the anxiety and am taking ativan until the cybalta is fully loaded in my brain. I know days seem like weeks when you feel the depression and anxiety. I guess it sounds cliche' but we need to hang in there. Please keep in touch it would be great to compare notes with someone else just starting on cymbalta Good Luck

I am going to start taking my cymbalta tomorrow. I am very nervous about it. I am afraid of the side effects. Can you tell me what or how you felt when you first started? right from your first pill? I would apreciate it I am a hypercontract... lol Thanks

Update I stopped my cymbalta and am now on wellbutrin xl. I thought I was getting better but I never really stopped waxing and waining so I withdrew the cymbalta by lowering the dose and starting a low dose of wellburtin and then after 2 weeks the switch was made. I am now feeling like my real self the one I thought I would never see again. i was so afraid I was never gonna be the same person I used to be the one that was happy and energetic and didn't cry all day BarbI hope you are doing better Hope this helps Good Luck and give me a update Barb