On Wed, 12 May 1999 09:06:45, "Frank Frst" <frank at fuerst.de> wrote:
> Hi,
>> I am looking for fluorescent derivatives of adenine. I want to try if
> I can measure adenine binding to my protein with one of these.
>> Unfortunately, I don't even know the names of common fluorescent
> derivatives of adenine - but I know that there are some.
>> Can anybody help me?
>> Thanks in advance, Frank
The oldest fluorescent analogue of adenine (& the only one I can think of) is
N(6)-ethenoadenine. The other fluoresecent relatives I can think of are derivatives
of AMP, such as TNP-AMP in which the trinitrophenyl group is attached to the 2'(3')
hydroxyl.
The ethenoadenine-containing nucleotides can be incorporated into poly(A). THere are
also etheno-derivatives of NAD, etc.
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