More than 90% of central nervous system drugs fail when they're tried in large human trials. The team at the Oxford Centre for Functional Magnetic Resonance Imaging of the Brain (FMRIB) hope that combining ...

A new drug that prompts cancer cells to self-destruct while sparing healthy cells is now entering phase I clinical trials in humans. The drug, called PAC-1, first showed promise in the treatment of pet dogs ...

A promising method of immunotherapy to treat children with relapsed acute lymphocytic leukemia (ALL) is opening at the University of Wisconsin Carbone Cancer Center and American Family Children's Hospital. ...

Children with acute lymphoblastic leukemia who had a certain gene variant experienced a higher incidence and severity of peripheral neuropathy after receiving treatment with the cancer drug vincristine, according to a study ...

Maybe you "trust Tylenol" or (like this writer) you're "all Advil." Research proves that both painkillers work, but many of us, including our doctors, can't help but have a preference shaped by experience ...

How can we keep more people from joining the ranks of the 29 million Americans already diagnosed with diabetes? What if we could tell with precision who has the highest risk of developing the disease, and ...

Mindfulness meditation practices resulted in improved sleep quality for older adults with moderate sleep disturbance in a clinical trial comparing meditation to a more structured program focusing on changing ...

Ovarian cancer patients throughout Europe and the United States could soon be treated with a new drug discovered through pioneering research at the University of Sheffield funded by Yorkshire Cancer Research.

According to a multinational clinical trial involving nearly 20,000 young women, the human papilloma virus vaccine, Cervarix, not only has the potential to prevent cervical cancer, but was effective against ...

A multi-institutional team of hearing and communication experts led by the Keck School of Medicine of the University of Southern California (USC) is breaking sound barriers for children born without a hearing nerve in a clinical ...

About 80 percent of studies of U.S. medical interventions use randomized controlled trials (RCTs), the gold standard of laboratory research. But only about 18 percent of studies of U.S. health care delivery ...

Monitoring participants' biological clocks may be the quickest way to determine the effectiveness of experimental drugs currently under development to treat Angelman syndrome: a debilitating genetic disorder ...

Pioneering prostate cancer drug abiraterone significantly extends the lives of men with advanced prostate cancer if given before chemotherapy, the results of a major phase III clinical trial have shown.