Hair is a useful matrix for drug analysis, as it can be used to show historical drug use. Parent drugs are often present in high concentrations, and the matrix is stable over time.
This poster describes the use of the Biotage® Lysera to pulverise and extract hair samples, with ISOLUTE® SLE+ supported liquid extraction columns to clean up the samples prior to analysis. Limits of quantitation set by the Society of Hair Testing for amphetamines are achievable with the described method (0.2 ng/mg).
SoHT 2017, Cardiff UKTags: Amphetamine,
Amphetamines,
Bead Ruptor,
Column,
Drugs of Abuse,
English,
Forensic,
GC-MS,
Hair,
MDA,
MDEA,
MDMA,
Methamphetamine,
Posters

Biotage® Lysera is the most advanced and easy to use bead mill homogenizer available. It is specifically designed for grinding, lysing, and homogenizing biological samples prior to sample preparation.

The convenient front-loading design maximizes laboratory bench space, and the removable tube carriage allows for sample pre-cooling and more efficient sample loading. The Biotage® Lysera stores up to 99 programs for standardized and reproducible results, and has an advanced sample temperature monitoring system and a multilingual user interface.

Optimized tube motion ensures highest performance

Biotage® Lysera is designed with a unique carriage motion to ensure that the intra-tube bead movement reduces swirling and results in the highest bead impact forces of any bead mill on the market. The increased power of the Biotage® Lysera decreases processing time and reduces sample heating to maximize sample homogenization efficiency

Increased Recovery

The Biotage® Lysera unique tube carriage motion coupled with sample specific bead beating materials ensure that a thorough homogenate is achieved regardless of the sample type. The high lysing efficiency of the Biotage® Lysera results in a increase in analyte recovery and increases the sensitivity of the downstream assay.

Wide range of bead kits for any sample type

Biotage offers users ultimate flexibility with a range of bead beating tubes and lysing matrices to support homogenization of any sample type.

Note: Biotage® Lysera Tube Carriages are sold separately.

About Biotage

Biotage is a global Life Science company that develops innovative and effective solutions for separation within organic and analytical chemistry, as well as for industrial applications. Biotage is listed on NASDAQ Stockholm.