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Biography

Dr. Grame F. Mason develops experimental models and methods for studies of brain metabolism using 1H and 13C Nuclear Magnetic Resonance (NMR) in conjunction with 13C isotopic labeling in vivo. His work began during his graduate studies at Yale where he used a rat model for the experimental determination of brain glucose transport kinetics and substrate competition for oxidative brain metabolism. Dr. Mason received further training at the University of Alabama at Birmingham, where he guided the group's 13C-labeling studies of the human brain in vivo in the 4.1T whole-body MR system. Dr. Mason currently studies metabolism and neurotransmission in the brain in vivo, including effects of psychiatric disorders and substances such as alcohol and nicotine; Dr. Mason examines healthy subjects and patients to investigate relationships among GABA, glutamate, and glutamine concentrations and their rates of synthesis and release in the brain, in particular with regard to effects of alcohol and nicotine in acute and chronic use.

Education & Training

PhD

Yale University (1991)

BS

The Pennsylvania State University, Nuclear Engineering, Minor in Spanish (1986)

Postdoctoral Fellow

University of Alabama at Birmingham, Center for Nuclear Imaging Research, Birmingham, AL