Dr Stanzani explains that fungal cells are very similar to human cells, and that drugs which are toxic to fungals cells may have the same effect on human cells.
Mortality in invasive aspergillosis depends largely on the timing of the intervention, timely diagnosis and the state of the patient’s defences – treatment is much more effective when people have an intact immune system.

My "questions and answer" sheets I use to revise. These sheets are much like the look, cover, copy sheets I used as a young child learning to spell and, although a primitive idea, they help me ensure I learn the topic.

This animation shows a simplified version of the macrophage's role in the initiation of atherosclerosis. In an atherosclerotic-prone blood vessel, macrophages invade the subendothelial space. Oxidised Low-Density Lipoproteins (oxLDL) present within the vessel wall will bind to scavenger receptors on the macrophage's surface, such as CD36. This will activate the macrophage, and it will phagocytose the oxLDL. As this process continues, the macrophage increases in size and forms a Foam Cell, which is too large to pass between the endothelial cells back into the lumen. Therefore, the foam cells remain in the subendothelial space and are the main cells present within an atherosclerotic plaque.
***
Done for Student Selected Component (SSC), University of Aberdeen. Year 2. 2011.
Made in Adobe Photoshop CS2 and Adobe Imageready.

This animation shows a simplified version of the macrophage's role in the initiation of atherosclerosis.
In an atherosclerotic-prone blood vessel, macrophages invade the subendothelial space. Oxidised Low-Density Lipoproteins (oxLDL) present within the vessel wall will bind to scavenger receptors on the macrophage's surface, such as CD36. This will activate the macrophage, and it will phagocytose the oxLDL. As this process continues, the macrophage increases in size and forms a Foam Cell, which is too large to pass between the endothelial cells back into the lumen. Therefore, the foam cells remain in the subendothelial space and are the main cells present within an atherosclerotic plaque.
***
Done for Student Selected Component (SSC), University of Aberdeen. Year 2. 2011.
Made in Adobe Photoshop CS2 and Adobe Imageready.

This diagram was created to summarise my dissertation. It shows numerous methods of immune evasion methods of a cancer cell. I did a lot of research around this subject and never found a diagram that brought this number of methods together, so created one.

This is a diagram I created to summarise the immune response, complete with friendly, loveable cartoon immune cells designed in an attempt to make what can be a very complicated and confusing subject seem a little less threatening. The students I taught the subject to loved the "cute" summary format and found immunology to be a much more approachable revision topic as a result!
Since this image has been so popular with all you lovely people, I have also written a comprehensive article on the immune response - complete with lots of illustrations - which is available here on Geeky Medics: http://geekymedics.com/2014/07/02/immune-response/
Enjoy and good luck!

Uveal melanoma is a rare but very aggressive malignancy: independently of the currently available therapies, 50 % of patients will develop metastasis and median survival time of these patients is only less than 8 months.

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