Because of the complex nature of cancer care, collaboration with the adolescent's oncologist is highly recommended," according to the opinion, which outlines options for prophylactic menstrual suppression (combined hormonal contraceptives, progestin-only therapy, and gonadotropin-releasing hormone agonists) and emergent treatment of acute uterine bleeding (hormonal therapy, antifibrinolytics, and surgical options for patients who fail medical therapy).

With the advent of field-deployable thromboelastography, it may also become possible to administer freeze-dried platelets, targeted procoagulants, such as recombinant Factor VIIa or activated prothrombin complex, or antifibrinolytics such as tranexemic acid.

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