Republicans opposed to a Rice nomination have bandied about Kerry's name for weeks, and Thursday, Senate Minority Leader Mitch McConnell told CNN that Kerry would be a "popular choice with the Senate."

It's ironic that several prominent Republicans are rallying behind Kerry, just eight years after their party demonized him during his failed 2004 presidential campaign against President George W. Bush.

Kerry remembered that experience in a statement he released about Rice.

"As someone who has weathered my share of political attacks and understands on a personal level just how difficult politics can be, I've felt for her throughout these last difficult weeks, but I also know that she will continue to serve with great passion and distinction," Kerry said.