If you are a Small Business customer, find additional troubleshooting and learning resources at the Support for Small Business site.

Some applications are incompatible with a Click-to-Run
installation of Microsoft Outlook 2010. For example, Windows Mobile Device
Center or Exchange ActiveSync does not detect Outlook 2010 as installed.

For more information about extensibility support matrix for
the Outlook platform on Click-to-Run, see the following table.

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Extensibility feature

Click-to-Run on a 32-bit
version of operating system without Outlook installed

Click-to-Run on a
32-bit version of operating system with Microsoft Office Outlook 2007 or
earlier versions installed

Click-to-Run on a 32-bit version of
operating system with Outlook 2010 installed

Click-to-Run on a 64-bit
version of operating system without Outlook installed

Click-to-Run on a
64-bit version of operating system with 32-bit version of Outlook
installed

Click-to-Run on a 64-bit version of operating system with
64-bit version of Outlook installed

Outlook add-ins that use Outlook Object Model (OM)

Supported

Supported

Supported

Supported

Supported

Add-ins
should work, with the understanding that older add-ins might break because of
deprecation of command bars in Outlook 2010, not load or install because of
setup issues, or other compatibility issues.

External applications that use Outlook OM only

Not
supported

Not supported

Not supported

Not
supported

Not supported

Not supported

Outlook add-ins that use Outlook OM and extended
MAPI

Not supported

Not supported

Not
supported

Not supported

Not supported

Not
supported

External applications that use simple MAPI
MAPISendMail

Supported

Supported

Supported

Supported

Supported

Not
supported

External applications that use simple MAPI calls other than
MAPISendMail