The funny thing about the Golden Age of comics, it gave us loads of characters who just fought gangsters, soldiers, and mad scientists. But it also gave us the likes of Superman, Green Lantern, the Spectre, the Marvel Family, Sub-Mariner, Black Adam, and Solomon Grundy. Even companies like Havey gave us stories like Black Cat story in Speed Comics #23. Yeah, Black Cat, Captain Freedom, and War Nurse spend seven pages fighting Japanese sailors who had invaded California, but on the final page, Shock Gibson is using his elctric powers to blast the Japanese submarines (or as the text put it "destroy the subs").

So, basically, it depends on the flavour of the stories that are going to be told, and the nature of the challenges that are going to be faced, and how the GM wants those challenges to be met.