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Abstract

At present nongonococcal urethritis is more common than gonorrhea among sexually active men attending venereal disease clinics in widely separated areas of the United States (1, 2). Efforts to control this urethritis epidemic are hampered by inadequate knowledge of the origin and epidemiology of nongonococcal urethritis. Although a variety of organisms have been cultured from patients with the disease, few studies have included controls with similar levels of sexual activity (3). Recently, T-mycoplasmas (4) and Chlamydia trachomatis (2) have been implicated as etiologic agents in controlled studies. However, other workers have isolated C. trachomatis as frequently from men with