In this paper, this variant — identified as SNP rs3829241— was associated with blond hair (vs. brown hair) with an OR of 1.55 (weighted average from table 1) and a significance of 6.2 * 10^-16. The authors hypothesize that this non-synonymous change to the protein is causal (ie, they do not believe the SNP is associated with a different, nearby causal gene).