Working to Fight an Epidemic

Ebola Virus’ high lethality have left thousands dead and tens of thousands orphaned since 1976. From a field of thousands of approved medicines, Atomwise discovered a drug candidate with no previous antiviral application that blocked Ebola infectivity across virus strains from multiple epidemics.

Left: Ebola virus replicating in a human host cell.

Computing New Treatments for MS

Multiple Sclerosis afflicts 2.5 million people with debilitating neurological symptoms, underscoring a vital need for new medicines. Atomwise explored 8.2 million molecules to discover a protein-protein inhibitor for the treatment of multiple sclerosis that is blood-brain-barrier penetrant, orally available, and highly efficacious in animals.