Peter Parker is facing a period of deep confusion in every aspect of his life. No longer is everything black and white, nor is it easy to know what the right thing to do is anymore. He's struggling to cope with the death of his dear Uncle Ben, while still feeling unfamiliar with his past in regards to his parents. He's also trying to hold down a relationship with Gwen Stacy, but she ultimately adds to his troubles when she finds herself in a dilemma of her own. Meanwhile in his professional capacity as Spider-Man, he's not finding it easy to differentiate between the villains, the heroes and the just plain hard-done by. He faces deadly battles with the formidable Rhino and the rage-filled Electro; the latter of who it turns out is just as frightened of his own power as everybody else is. It turns out that there is a darker force happening elsewhere, and when his friend Harry Osborn returns, he starts to see OsCorp's sinister involvement.