Background: Markedly overweight people can develop progressive proteinuria and kidney failure secondary to obesity-related glomerulopathy (ORG). Glomerular lesions in dogs with experimentally induced obesity are similar to those in people with ORG.
Objectives: The aim of this study was to evaluate ...

BACKGROUND Myocardial fibrosis is a hallmark of hypertrophic
cardiomyopathy (HCM). Human patients with HCM have high serum
concentrations of biomarkers of collagen synthesis, indicating a profibrotic state.
This abnormality exists in sarcomere mutation carriers both with and without
overt left ventr...

Diabetic ketoacidosis (DKA), a complication of diabetes mellitus, is a severe metabolic disease that often requires intensive treatment. Diagnosis of ketosis associated with DKA can be difficult due to variability in the metabolic state of DKA patients. Recognition of the clinical signs and definiti...

Communication skills are considered a core clinical skill in human medicine. Recognizing the importance of communication skills and addressing them in veterinary curricula, however, is just beginning. In the fall of 2003, the Atlantic Veterinary College, University of Prince Edward Island, markedly ...

OBJECTIVE: To determine whether pedometers can be used to measure physical activity in dogs. DESIGN: Cross-sectional study. ANIMALS: 26 dogs. PROCEDURE: To determine pedometer accuracy, number of steps recorded with the pedometer as dogs walked, trotted, and ran for a distance of approximately 30 m ...

Failure to grow in pups and kittens can be the result of many factors. Dietary, metabolic, endocrine, parasitic, neoplastic, and genetic diseases may be responsible for a failure to thrive alone or in concert with other disorders. A complete history, physical examination, complete blood cell count, ...

Pituitary corticotroph macrotumors occur in 10% to 50% of dogs with PDH. Clinical signs may be only those of hypercortisolism or may include neurologic signs such as stupor, inappetance, circling, or pacing. Currently, CT and MRI are the only tests that can confirm the presence of a pituitary macrot...

A course book on presenting symptoms, and diseases of internal organs in dogs and cats. There is a self-assessment section containing 100 multiple-choice questions. Other titles in the same series have dealt with small animal surgery, cytology, pharmacology and toxicology..

Double-phase parathyroid gland scintigraphy, using technetium Tc 99m sestamibi, correctly identified the existence and location of a parathyroid adenoma in a dog with primary hyperparathyroidism. The parathyroid adenoma was removed surgically 2 days after scintigraphy. An area of focal radionuclide ...

An 11-year-old mixed-breed dog was examined because of chronic diarrhea, anorexia, and weight loss. Clinicopathologic abnormalities included anemia and hypoalbuminemia, and protein-losing enteropathy was identified. Acute, unilateral, femoral artery thrombosis developed before the cause of the prote...

Dietary therapy affects diabetes management in the dog and cat directly through control of blood glucose and indirectly through control of obesity and lipid abnormalities. Caloric intake, the feeding schedule, food form, macronutrient composition of the diet, and the presence of any concurrent probl...

Six dogs were fed each of nine diets to evaluate the effects of diet on fecal occult blood test results. The diets represented a range of different type (i.e. canned, dry or semi-moist), protein and vegetable constituents, and fiber contents. Each diet was fed twice daily for five consecutive days; ...

This article reviews potential causes of insulin resistance in dogs and cats. These include hyperadrenocorticism, dioestrus or pregnancy, acromegaly, obesity and excess glucagon secretion. Clinical recognition and diagnosis are discussed..