Male contraceptive injection shows promise

The groundbreaking trial could lead to the rebalancing of the burden of responsibility for birth control between the genders after a decade where the obligation has been increasingly borne by women.Harriet Agerholm | AP | October 29, 2016, 08:33 IST

A male contraceptive jab which lowers sperm count has proved 96% effective in a new study - almost as effective as the female pill. The groundbreaking trial could lead to the rebalancing of the burden of responsibility for birth control between the genders after a decade where the obligation has been increasingly borne by women. Yet a significant number of side effects, including depression, acne, and heightened libido caused 20 men to drop out and ultimately led to the trial stopping early.

The injection was 96% effective at preventing pregnancies among couples during a year-long trial, with only four pregnancies taking place out of the 266 couples that tested out the drug. The resulting pregnancy rate of 1.57 per 100 users is comparable to that of the combined contraceptive pill, which has a rate of less than 1 pregnancy per 100 women who use it.

The jab contains two hormones: progestogen that blocks sperm production by acting on the brain's pituitary gland and testosterone that counterbalances the reduction in male hormones. The Independent

After the trial, three in four of the men said they would be willing to continue using the injection.

Couples used both the injections and other methods of birth control for an initial period before entering the study's "efficacy phase" where they relied on the injections alone. During this period the men were given injections every two months for over a year. The research is published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

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