The Skeptics Society is involved in a number of activities. One of its primary activities is the publication of Skeptic magazine. Skeptic is a quarterly magazine available by subscription or on major newsstands in the U.S. and Canada. The magazine examines many fringe science and paranormal claims. Its cover stories have ranged from examination of alleged UFOs in religious icons[2] and theories of the likelihood of artificial intelligence,[3] to tributes to luminaries such as Isaac Asimov[4] and Ernst Mayr.[5] Some editions feature special sections devoted to a particular topic or theme that is examined through multiple articles by different authors, such as intelligent design and alternative medicine. In each issue of Skeptic is a pull-out issue of Junior Skeptic, a skeptical magazine aimed at children. The Skeptics Society also publishes eSkeptic, a weekly email newsletter on skeptical topics.

The Skeptics Society hosts a website containing information on skepticism-related topics and provides information to the media about such topics.

The Skeptics Society distributes two free podcasts. In 2007, Skepticality was adopted as the group's official podcast. In addition to Skepticality, the Skeptics Society also has the podcast MonsterTalk.