Many consumers of StemEnhance reported, after a few months of daily consumption,
reduction of hair graying. Consumers reported a slow return to oneâ&#x20AC;&#x2122;s natural hair color.
Although such reports were first received with skepticism, a brief search of the scientific
literature rapidly provide evidence that bone marrow stem cells have the ability of
differentiating into melanocytes responsible for hair pigmentation, therefore providing for
a mechanism of action behind such observation.
Altering hair color by restoring oneâ&#x20AC;&#x2122;s natural hair color has little relevance when
considering human health, however such an effect would constitute a strong indication of
the rejuvenating properties of StemEnhance. In this study we investigated the effect of
daily consumption of StemEnhance on the density of white in the hair of middle age men.

Methods
In brief, 6 healthy men between 46 and 61 years of age exhibiting significant hair graying
were selected. The participants were provided StemEnhance and were instructed to
consume 2 capsules three times daily. The subjects were instructed to report any adverse
reaction. Finally, participants were instructed not to change their hairstyle, grooming
products or schedule of haircuts for the duration of the study.

1

At baseline and once monthly visual and instrumental hair color evaluations were
conducted using Matched Scientific Photography. The technicians involved in this study
were all certified by a Board Certified Ophthalmologist using the Farnsworth-Munsell
100 Hue Test, which determine a personâ&#x20AC;&#x2122;s ability to discern color against a black
background. Finally, at each visit the participants were asked to fill a SF-36 Quality of
Life Questionnaire.

Results
No adverse effects or unexpected reactions of any kind were observed on any of the
participants. Most participants empirically reported a greater level of energy and an
overall greater level of well being for the duration of the study, which was objectively
measured using the SF-36 Quality of Life Questionnaire.

A

reduction

in

the

density of white was
seen in all participants
in both sides of the
head and in the back.
Although the effect was
more pronounced on
the sides of the head (19%) than in the back
(-17.5%), the difference
was

not

significant.

Therefore, the data was
pooled and on average the reduction in white density gradually reached -18.5% after 6
months of consumption, ranging between -11% and -28.6%. The difference measured

2

was statistically significant (p<0.001). In at least three participants empirical observations
also suggested a thickening of the hair, although this was not quantified.

This series of photographs was taken from the left side of the head of one participant at baseline and
then after 3 and 6 months of consumption of 1 gram of StemEnhance 3 times a day. Photographs
taken from the right side of the head show similar darkening of hair color.

Photographs taken from the back of the head of one participant at baseline and then after 12 weeks of
consumption of 1 gram of StemEnhance 3 times a day.

Discussion

As mentioned previously, reversal of hair graying does not carry much relevance to
overall health. Hair graying is a natural process associated with aging and many people
with graying hair have very good health. Yet, hair color is a symbol of rejuvenation and
so far nothing is known which, when taken orally, can naturally bring back oneâ&#x20AC;&#x2122;s natural
3

hair color. Therefore the effect of StemEnhance on hair graying reported in this study can
have far-reaching implications.

These observations lend a strong support to the fact that stem cells from the bone marrow
can migrate in various tissues and become cells of these tissues. Although no clinical test
was used to actually quantify the increased density of melanocytes associated with hair
follicles, the fact that the effect was seen in all participants strongly suggests that the
reduction in white density was caused by the migration and differentiation of stem cells
into melanocytes. Given the irrelevance of hair color in health, it is fair to assume that if
stem cells have migrated to become melanocytes, the body has certainly guided many
stem cells to migrate and become other types of cells, further supporting the regenerative
properties of StemEnhance.

Although this was not the purpose of the study, the fact that StemEnhance is the only
product taken orally that was shown to affect hair color, this study lends support for a
entirely new application of StemEnhance in cosmetology. Furthermore, empirical
observations made in this study support prior reports that StemEnhance elevates mood
and enhances overall quality of life.