hypothyroidism

Deficient functioning of the thyroid gland.
Congenital hypothyroidism can lead to cretinism in children. In adults the
condition is called myxedema. More common in women, it
causes physical and mental slowness, weight gain, sensitivity to cold, ,
and susceptibility to infection. It can be due to a defect of the gland
itself or a lack of iodine, both of which
can lead to goiter or to inadequate stimulation
of the thyroid gland by the pituitary. It is treated with the hormone thyroxine.