RNAscope® Technology

RNA Detection

New advances in RNA in situ hybridization transforms molecular detection with morphological context enabling new applications. See how scientists use RNA ISH to extract new data dimensions.

RNA ISH and IHC

Combine the protein detection capabilities of IHC with localized mRNA expression analysis
using RNAscope ISH in order to build a more complete and robust picture
of the molecular mechanisms of any biological pathway.

Transcriptomic biomarker discoveries lead to
a more thorough investigation requiring scientists to validate
the location of RNA expression using RNAscope(R) technology.

RNA ISH and PCR

qPCR is commonly used for high throughput quantification of multiple target genes within the entire sample. Nevertheless, digital analysis at the single level using real-time PCR is cumbersome and does not preserve the cellular relationship and tissue structure making RNA ISH a perfect complement to create a full RNA expression profile.

Why investigate RNA?

Whitepaper: A guide to RNA as a biomarker and its detection: unlocking the potential of RNA as a clinically valuable biomarker, the latest RNA analysis technologies are changing the way we perceive and utilize this intriguing molecule. In our new free-to-download whitepaper we explore what the RNA Revolution means for biomarkers, now and in the future.

Get it today to learn more about:

The Biomarker: What makes a valuable biomarker, and how a direct path from RNA biomarker discovery to the clinic is vital, avoiding the use of DNA or protein surrogates.

The Method: A biomarker is only as good as its routine analysis methodology, but what constitutes the optimal biomarker method? Advantages and pitfalls of existing methods for routine biomarker analysis will also be discussed.

The Future: How the utilization of RNA as a biomarker is achieved through the latest RNA analysis methods, such as our very own RNAscope®