T-Lymphocyte Subsets and Schizophrenia

Abstract

Viruses have long been sought as possible etiologic agents in several neurological and psychiatric disorders of unknown etiology such as amyotrophic lateral sclerosis (Zil’ber et al., 1963), multiple sclerosis (Marie, 1884), Parkinson’s disease (von Economo, 1931; Marttila et al., 1981), and schizophrenia (Menninger, 1922). In schizophrenia, evidence for a pathogenic role for viruses, especially those of the genus Herpesvirus, has primarily been indirect and has included behavioral, neuropathological, and most importantly immunological abnormalities (reviewed by Kaufmann et al., 1984).

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