LONDON and PHILADELPHIA, June 5 /PRNewswire/ -- Thomson Reuters, the
world's leading source of intelligent information for businesses and
professionals, today announced the addition of Prous Science routes of
synthesis (ROS) data to the Newport Horizon Premium and Newport Vision
Premium solutions. An ROS focused search allows users to identify active
pharmaceutical ingredients (APIs) according to an intermediate or reagent
used, number of available routes or by patents referenced in a given route.
Provided free of charge to current subscribers of the Premium systems, this
new dataset, which provides an exciting compliment to the kilogram demand
data released in March, enhances product targeting, business development
and competitive intelligence by helping users to understand better the
chemistry and manufacture of APIs.

The true or original manufacturing process used for a particular API is
usually well protected by patents, making it challenging to devise
equivalent, cheaper or more efficient processes without infringing on the
originator's intellectual property. The new dataset will help to remedy
this by providing extensive information for more than 2,500 APIs,
consisting of:

-- Full chemical name

-- CAS number

-- Synthesis route diagram

-- Text commentary (with each step indexed to the diagram)

-- Patent references (linked to the patent page)

-- Intermediate chemicals and CAS numbers

-- Reagent chemicals and CAS numbers

-- Scientific journal references

"Understanding the 'recipe' of how a particular active ingredient is
made -- or could be made -- is of vital importance to API manufacturers,
generic companies and innovators," said Mike Chace-Ortiz, Senior Director,
Product Strategy, Thomson Reuters. "By providing access to this important
data, Newport Horizon Premium and Newport Vision Premium now allow our
customers to gauge which patents are involved, what raw materials are
needed, the cost and complexity of the process and whether specialized
equipment or facilities must be bought or constructed."

Thomson Reuters is the world's leading source of intelligent
information for businesses and professionals. We combine industry expertise
with innovative technology to deliver critical information to leading
decision makers in the financial, legal, tax and accounting, scientific,
healthcare and media markets, powered by the world's most trusted news
organization. With headquarters in New York and major operations in London
and Eagan, Minnesota, Thomson Reuters employs more than 50,000 people in 93
countries. For more information, go to http://www.thomsonreuters.com.

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