var] or high Hb F concentrations can be recognized by the separate elution of variant peaks or by abnormally high peaks on HPLC, and these abnormal findings arise mostly from genetic alterations in the globin genes (2,3).

Alkaline electrophoresis is rapid, reproducible, and capable of separating common hemoglobin variants, such as hemoglobin A (Hb A), Hb F, Hb S, and Hb C, but Hb S, Hb D, Hb G, and Hb Lepore are unresolved from each other, as are Hb C, Hb [A.

The percent concentrations in the current study are lower than the published cord blood data by 15% for all Hb F and by a median 36% for the Hb in other hetero- and homozygous patterns (range, 22-40%).

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