Macross Galaxy colonization fleet is the 9th Large-scale emigration fleet, the 51st Super-Long-Distance colonization fleet and the 21st New Macross Class Emigration Fleet, which departed from the planet Eden sometime in 2031 (approximately 10 years before the Macross Frontier fleet departed in 2041). The Macross Galaxy was planned and supported by large corporations and the many new technologies designed onboard the fleet continually evolve as the fleet travels through space. Chief among these evolving technologies was the pursuit of cybernetics and cybernetic implants in living beings. The Battle-class space stealth aircraft carrier Battle 21/Battle Galaxy is the offensive unit attached to the flagship of 21st New Macross class immigration fleet, Macross Galaxy. Although it was initially presumed to have been destroyed by the Vajra in the early stages of conflict in 2059, it was later discovered that Grace O'Connor had hidden the vessel. The Battle Galaxy is similar in structure to Battle Frontier but both the internals and electronic equipment are different.

Unlike its sister fleet, Macross Frontier, Macross Galaxy uses chemical plants and does not have Zentradi residents. One of its most prominent citizens is the idol singer Sheryl Nome. While en route towards the center of the galaxy, this fleet sustained a large-scale attack by the Vajra. The Macross Galaxy featured many escorts of which two were warships named the Kaitos (destroyed by the Vajra) and Dulfim. The mainland has no news or amusement facilities. Farming facilities and marine cultivation ships are remodeled into synthetic food manufacturers. As a result, the production capacity of the whole fleet increased, enabling production and development of such things as the VF-27.