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Findings suggest that ECE environments are similar to other indoor environments such as schools and residences, and that mitigation strategies may be warranted to reduce exposures to some chemicals, especially formaldehyde. More research is needed to identify sources of toxicants and support outreach efforts to improve environmental quality.

Both prenatal and childhood PBDE exposures were associated with poorer attention, fine motor coordination, and cognition in the CHAMACOS cohort of school-age children. This study, the largest to date, contributes to growing evidence suggesting that PBDEs have adverse impacts on child neurobehavioral development.

The high variability we observed in children’s DAP metabolite concentrations suggests that single-day urine samples provide only a brief snapshot of exposure. Sensitivity analyses suggest that classification of cumulative OP exposure based on spot samples is prone to type II classification errors.

Results suggest that exposure to BPA during pregnancy is related to reduced total T4 in pregnant women and decreased TSH in male neonates. Findings may have implications for fetal and neonatal development.