Joey Bosa (99) of the San Diego Chargers and Melvin Ingram (54) force a fumble by Trevor Siemian (13) of the Denver Broncos during the second quarter on Sunday, October 30, 2016. The Denver Broncos hosted the San Diego Chargers.

Three things to watch:

Under pressure. Los Angeles defensive end Melvin Ingram is third in the NFL this season with 7½ sacks, including 1½ in the season opener against the Broncos in Denver. Teammate Joey Bosa has 5½ sacks, forming one of the best pass-rushing duos in the league. The Broncos have given up 17 sacks through five games, tied for 11th most in the league.

Big-play Gordon. Chargers RB Melvin Gordon has been one of the best receivers at his position in the NFL this season. His four touchdown receptions, including one against the Broncos on Sept. 11, are the most among running backs. Gordon has only one 100-yard rushing performance this season, but he’s a big threat coming out of the backfield.

Game Plan

When the Broncos run. The Broncos are coming off their worst rushing performance of the season, gaining 46 yards on 17 carries in a 23-10 loss to the Giants. It was the first time Denver had been held under 110 yards this season. They should have an opportunity to bounce back against the Chargers’ league-worst rushing defense, which is surrendering 152.5 yards per game. Edge: Broncos.

When the Chargers run. Denver slipped to No. 2 in the NFL in rush defense (70.2 yards per game) after Orleans Darkwa of the Giants ran for 117 yards Sunday. He was the first opposing running back to eclipse the 60-yard mark against the Broncos. Melvin Gordon had 54 yards on 18 carries in the first meeting between these two teams. Edge: Broncos.

When the Broncos pass.Trevor Siemian has thrown six interceptions through five games. He threw only 10 interceptions in 14 games in 2016. Teams are averaging only 186 passing yards per game against Los Angeles, and the 18 sacks the Chargers have piled up in six games are tied for fifth in the NFL. Edge: Chargers.

When the Chargers pass. Chargers QB Philip Rivers has been sacked only seven times this season and is on pace for a career-low total in that category. The Broncos limited his effectiveness in the first matchup by effectively erasing tight ends Hunter Henry and Antonio Gates. Henry had five catches for 90 yards last week against the Raiders. Edge: Broncos.

Special teams. The Broncos secured their win over the Chargers in the first meeting when Shelby Harris blocked a field-goal attempt by Younghoe Koo. Koo has since been released by the Chargers, who replaced him with veteran Nick Novak. The Broncos have had their own field-goal trouble, with Brandon McManus already missing five kicks. Denver will be without punt returner Isaiah McKenzie. Edge: Chargers.

The Broncos last spring entered the middle rounds of the NFL draft on the hunt for game-breaking talent. And when Carlos Henderson (third-round pick) and Isaiah McKenzie (fifth) started making plays under the glaring August sun at training camp, it appeared Denver would have a youthful injection to its sagging offense in 2017.