Decreasing Activity of an Enzyme

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Some enzymes experience a decrease in activity proportional to the concentration of their products. This phenomenon could be an example of what process?

A. Feedback inhibition

B. Non-competitive inhibition

C. Allosteric activation

D. Both A and B

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Correct Answer: D.Both A and B

Many cellular enzymes exhibit decreasing activity with increasing levels of reaction product. This feedback inhibition help regulate the activity of enzymatic processes. Often this process occurs through non-competitive inhibition. The product of the chemical reaction binds to the enzyme in a location other than the active site, which causes a conformational change in the enzyme and decreases enzymatic activity. Allosteric activation describes a process in which enzymatic activity is increased because of binding of some molecule to a site other than the active site.

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