Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Oncostatin M (OSM)
No significant cross-reactivity or interference between Oncostatin M (OSM) and analogs was observed.

Description:

LS-F5168 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the detection of Mouse OSM / Oncostatin M in samples of Plasma and Serum. It is based upon a Sandwich assay principle and can be used to detect levels of OSM / Oncostatin M as low as 6.3 picograms per milliliter.

Sample Type:

Plasma, Serum

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Detection Range:

15.63 - 1000 pg/ml

Sensitivity:

6.3 pg/ml

Assay Time:

4.5 h

Precision:

Intra-Assay: CV<10% Inter-Assay: CV<12%

Quality Assurance:

Due to their limited shelf life, LSBio ELISA kits are not typically stocked as finished goods. Upon receipt of an order each kit is assembled and tested to ensure that it meets specifications before shipping. Minor changes may occur to the Range, Sensitivity, and Precision. In the event of a significant change the order would be confirmed with the customer before shipping ELISA kit lot numbers reflect the date of final assembly and testing for each specific kit rather than a bulk manufactured lot. All kits are tested to confirm that they fall within their defined Inter- and Intra- assay coefficient of variation.

Kit Components:

Coated 96-well Strip Plate

Adhesive Plate Sealers

Standard (Lyophilized)

Sample Diluent

Detection Reagent A (Green)

Detection Reagent B (Red)

Assay Diluent A

Assay Diluent B

TMB Substrate

Stop Solution

Wash Buffer (30x concentrate)

Restrictions:

For research use only.

About OSM / Oncostatin M

Description: Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.