In Ellingwood's Therapeutist of 1908, it is reported that gelsiminine from Gelsemium sempervirens (yellow jasmine) 'will check the hot flashes that occur during or after the menopause in nervous, plethoric or relaxed women at a dose of 1/250 grain' (Dougherty-Trexler 1908) and elsewhere a single dose of 'ten drops of specific gelsemium, if necessary followed up by 3 drop doses every hour is excellent for the hot flashes that are apt to occur during the menopause' (Henschen 1908).

This edition includes considerably more herbs, ones that would now be an obvious omission from the original text such as Caulophyllum thalictroides, Centella asiatica, Eleuthrococcus senticosus, Olea europaea, Panax ginseng and the Vinca species, and a good selection of scheduled or restricted herbs such as Acorus calamus, Datura stramonium, Digitalis species and Gelsemium sempervirens.

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