the lang lab | notebooks
| online archives

Laboratory Notebooks

Below is a list of my lab notebooks. The important ones (i.e. the ones leading to publications) are available below as PDFs (these are huge files . . . patience is key). The goal when I started this practice was to establish a permanent digital record of published experiments, to promote transparency, and to motivate myself to keep good notes. As it turns out, I am not the only person doing this; this trend has become known as Open Notebook Science. In a 2011 PLoS ONE paper, I included the full notebook as supplemental material. You can read about this on Mike Eisen's blog: Notebook S1: Scientific publishing awesomeness

Evolution 9: Bulk-fitness assays. Our first major project at Lehigh. Quantifying the fitness effect of hundreds of mutations from evolved populations One of two companion notebooks to the Buskirk et al. (2017) PNAS paper. pdf [52.1 Mb, 200 pages]

Evolution 2: Carbon assimilation in Saccharomyces kudriavzevii. Experiments investigating the basis for the gain of inulin assimilation and the loss of the GAL pathway in this yeast.Available in the Lang lab.