A driver wearing only his underwear smashed into two 15-year-old girls on a rain-swept Queens street, killing one and injuring the other, law-enforcement sources said.

Dr. Warren Stanton, whose office in Glen Oaks is at the intersection where the accident occurred, said, “I was in my office with a patient when I heard what sounded like an explosion.

“One girl was lying in the middle of 80th Avenue with blood coming out of her mouth. She had one foot in heaven already.”

Stanton worked frantically to save her, but it was too late.

“As a physician I could do nothing. I just watched this girl go before me.”

Her friend was taken to Long Island Jewish Hospital where she was in stable condition with an ankle injury.

The names of the victims were not immediately released.

The car was traveling east on 80th Avenue and was trying to make a left onto 260th Street when the tragedy happened.

The driver was taken into custody but was later released.

Police sources said he had been clad only in underwear.

The distraught driver would not comment as he left the scene – fully dressed – but Meir Moza, who identified himself as the driver’s lawyer, said, “This was a tragic accident.”

Moza explained his client got drenched walking to his car in the rain. The man then took his pants off when he got into the car.

Elaine Recker, 39, who lives nearby, believes the girls had been returning home from an after-school shopping trip to a nearby mall.

“I think they were Catholic school girls. One was wearing a uniform,” she said.

The girl with the injured ankle “was sitting on top of a turned-over pail in the rain,” Recker said

“She was on her own. It was pouring rain, thunder, lightning. The streetlight was out.

“She was hysterical. Her mother arrived and was trying to calm her down. She put her arms around her daughter, and the two of them started sobbing uncontrollably. The daughter was distraught. The mother was just happy that her daughter was alive.”

Neighbors said the intersection is dangerous.

“They speed down 80th Avenue. There aren’t many speed bumps and I think that people take advantage of it. There have been accidents over the years, but nothing like this, not for 30 years,” Recker said.

Another neighbor Joseph Betteoheim, 43, complained, “There isn’t a single traffic light anywhere in the neighborhood. When it’s really dark it’s like a drag strip.”