RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in peptides and proteins and identify biomarkers related to cancer.

To assess which potential peptide and protein markers produced by human melanoma, lung, breast, pancreatic, and colorectal cell lines may be detectable in serum of patients from these five disease groups.

Secondary

To conduct further extensive investigation with respect to identification of the protein/peptide involved, determination of specificity for each cancer, and development of more sensitive assays to look for such markers in a wider population of patients, including those undergoing therapy.

OUTLINE: This is a multicenter study.

Blood samples are collected before surgical intervention or treatment to assess peptide and protein markers.

Eligibility

Genders Eligible for Study:

Both

Accepts Healthy Volunteers:

No

Sampling Method:

Probability Sample

Study Population

5 different tumour types

Criteria

DISEASE CHARACTERISTICS:

Diagnosis of 1 of the following advanced metastatic malignancies:

Malignant melanoma

Lung cancer

Breast cancer

Pancreatic carcinoma

Colorectal cancer

Advanced and/or metastatic disease

Hormone receptor status not specified

PATIENT CHARACTERISTICS:

Menopausal status not specified

PRIOR CONCURRENT THERAPY:

Not specified

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00974610

Locations

Ireland

Cork University Hospital

Recruiting

Cork, Ireland

Contact: Contact Person 353-21-492-1301

Mercy University Hospital

Recruiting

Cork, Ireland

Contact: Contact Person 021-4271971

Mater Private Hospital

Recruiting

Dublin, Ireland

Contact: Contact Person 01 885 8888

Beaumont Hospital

Recruiting

Dublin, Ireland, 9

Contact: Contact Person 353-21-492-1301

Mater Misericordiae University Hospital

Recruiting

Dublin, Ireland, 7

Contact: Contact Person 353-1-858-569

St Luke's Hospital

Active, not recruiting

Dublin, Ireland

St. James's Hospital

Recruiting

Dublin, Ireland, 8

Contact: Contact Person 353-1-410-3545

St. Vincent's University Hospital

Recruiting

Dublin, Ireland, 4

Contact: Contact Person 353-1-209-4895

Adelaide and Meath Hospital, Dublin Incorporating the National Children's Hospital