Postdoctoral position in Tumor Immunology/Immunotherapy
A funded postdoctoral position is available immediately at the
University of Virginia, in Charlottesville, Virginia.
We have been working primarily on identification of peptide epitopes
for human melanoma-specific MHC-Class-I-restricted cytotoxic
T-lymphocytes (JI 150:2955, 1993; Science 1994). A result has been
identification of an epitope that is being used in a new clinical tumor
vaccine trial.
Ongoing projects include:
(1) identification of additional epitopes from melanoma,
(2) further characterization of the T-cell response to the
melanoma/melanocyte protein Pmel17(gp100),
(3) investigation of the CTL response to other solid human tumors, and
(4) investigation of the mechanisms of tumor-associated immune
non-responsiveness.
The applicant should have a background in cellular immunology,
should have some experience growing cytotoxic T-cells, and should be
interested in research at the interface between basic science and human
clinical applications. The role of the candidate is negotiable,
depending on his/her interests and expertise. It would include T-cell
generation, cellular assays, some molecular genetics, and protein
chemistry. Collaborations with the laboratories of Vic Engelhard, Ph.D.
(Microbiology) and Donald Hunt, Ph.D. (chemistry), combined with the
availability of patients and patient-derived material, provide numerous
research opportunities.
Salary would be between $20,000 and $25,000 annually. Travel for
scientific presentations will be funded by the laboratory. Funds already
exist for this position.
Start: immediately
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Craig L. Slingluff, Jr., M.D.
Associate Professor of Surgery
Chief, Division of Surgical Oncology
University of Virginia Health Sciences Center
cls8h at virginia.edu ph:(804)924-1505 fax:(804)982-1024