PhyloPTE/Peacefield - Phylogenetic Reconstruction used to improve the power of genome wide association studies (GWAS)

Sam Handelman Pharmacology, College of Medicine and Public Health, The Ohio State University

(March 15, 2012 10:30 AM - 11:30 AM)

Abstract

PhyloPTE/P (Phylogeny with Path to Event, in People) is a method to bridge the gap between large, gene sequencing based (and, in the near future, other *omic based) studies and phylogenetically-driven approaches developed in other fields, for example epistatic-effect detection using comparison of phylogenetic tree reconstructions for different genes. PhyloPTE/P should be of interest to a wide audience of investigators, including those in biomedical informatics or medical genomics, as well as those in systems biology or evolutionary biology, and serve as a software platform to foster collaboration between the two areas.

The MBI receives major funding from the National Science Foundation Division of Mathematical Sciences and is supported by The Ohio State University.
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