For the Consumer

Along with its needed effects, desloratadine (the active ingredient contained in Neoclarityn) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking desloratadine:

Rare

Anaphylaxis, such as, cough, difficulty swallowing, dizziness, fast heartbeat, hives, itching, puffiness or swelling of eyelids or around the eyes or face or lips or tongue, shortness of breath, skin rash, tightness in chest, unusual tiredness or weakness, wheezing

Some side effects of desloratadine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For Healthcare Professionals

Cardiovascular

Cardiovascular side effects of spontaneous nature reported during the marketing of desloratadine (the active ingredient contained in Neoclarityn) have included tachycardia and palpitations.[Ref]

Hypersensitivity

Hypersensitivity side effects of spontaneous nature reported during the marketing of desloratadine (the active ingredient contained in Neoclarityn) have included rash, pruritus, urticaria, edema, dyspnea, and anaphylaxis.[Ref]

Hepatic

Hepatic side effects have included elevated liver enzymes and bilirubin. Very rarely, hepatitis has been observed in clinical practice.[Ref]

Gastrointestinal

Gastrointestinal side effects have included dry mouth, dry throat, nausea, and pharyngitis.[Ref]

Nervous system

Nervous system side effects have included somnolence and dizziness. Psychomotor hyperactivity and seizures have been observed in clinical practice.[Ref]

An increase in the incidence of somnolence has been reported in clinical trials (n=1838) at doses of 10 mg/day and 20 mg/day (5.2% and 7.6%, respectively), compared to placebo (2.3%).[Ref]

General

General side effects have included myalgia and influenza-like symptoms.[Ref]

Consumer resources

Professional resources

Related treatment guides

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.