Specifications

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Applications

Western blot

Cellular activation

SDS-PAGE

Endotoxin level< 0.010 Eu/µg

FormLyophilised

Additional NotesManufactured using all non-animal reagents.

Concentration information loading...

Preparation and Storage

Stability and Storage

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

n/a

This product is an active protein and may elicit a biological response in vivo, handle with caution.

ReconstitutionCentrifuge the vial prior to opening. Reconstitute in 500ul sterile filtered water to a concentration of 1mg/ml.

General info

Alternative names

Beta urogastrone

EGF

Egf

EGF_HUMAN

Epidermal Growth Factor

Epidermal Growth Factor

HOMG4

OTTHUMP00000219721

OTTHUMP00000219722

Pro epidermal growth factor

URG

Urogastrone

see all

FunctionEGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.

Involvement in diseaseDefects in EGF are the cause of hypomagnesemia type 4 (HOMG4) [MIM:611718]; also known as renal hypomagnesemia normocalciuric. HOMG4 is a disorder characterized by massive renal hypomagnesemia and normal levels of serum calcium and calcium excretion. Clinical features include seizures, mild-to mederate psychomotor retardation, and brisk tendon reflexes.

Thank you for contacting us. The two active proteins are essentially the same, and both can be used to induce phosphorylation as they have been tested in functional studies. The only difference would be that ab9697 is supplied as lyophilized powde...