Use new therapeutic agents that target mediators of innate immunity that may be useful for other inflammatory skin diseases

Description:
Autoinflammation is a concept, first coined over ten years ago, to describe conditions that are characterized by episodes of seemingly unprovoked inflammation in the absence of T cell activation or high autoantibody titer. This term was applied to a group of rare monogenic periodic fever syndromes. Autoinflammation is increasingly recognized as fundamental to the pathogenesis of common skin diseases such as hidradenitis suppurativa, pyoderma gangrenosum, and psoriasis. In this session, the cutaneous manifestations and systemic complications are reviewed to enhance the learner's management of such conditions. The session is designed for medical dermatologists consulting on patients with complex medical or systemic diseases and who are interested in pathogenesis and future therapeutic targets.