Reproductive functions in most animals demonstrate seasonal fluctuations
that allow young to be born at a time of the year favourable for their
survival. Whether there is a seasonal change in the human ...

D-group chromosome translocations have been associated in isolated cases
with infertility in males. In this study, we demonstrated the effect of a
translocated D-group chromosome on spermatogenesis as it had ...

Studies using high dose testosterone (T) administration in normal men as a
male contraceptive have resulted in azoospermia rates of only 50-70%.
Previous studies of T and progestogen combinations have shown ...

In this study we tested the effectiveness of the combined administration
of cyproterone acetate (CPA) and testosterone enanthate (TE) in
suppressing spermatogenesis. After a control phase of 3 months, 15 ...

Three men who volunteered as normal subjects were found to have abnormally
high levels of serum follicle-stimulating hormone (FSH) despite having
normal seminal fluid analyses and fertility. Two of the men ...

A man with IHH and anosmia presented in 1980. He was successfully treated
with various hormonal regimens; four children were conceived with hCG or
pulsatile GnRH therapy. The patient discontinued GnRH after ...

The relative roles of FSH and LH in the control of human spermatogenesis
are not well established. We previously reported that supraphysiological
doses of hCG can stimulate sperm production in gonadotropin- ...

The concept that androgen alone can provide an effective male
contraceptive has been tested in a multicentre, multiphase trial by the
World Health Organization. Results from this trial showed that an ester ...