As part of the Joining Forces initiative, the first lady will appear on the Debby Ryan sitcom's May 16 episode.

After booking appearances on the Parks and Recreation finale and Nashville, Obama is headed to Disney Channel's youth-targeted original comedy Jessie for a cameo in the May 16 episode airing 8 p.m. ET/PT.

As part of the White House's Joining Forces initiative, Obama will appear as part of a storyline that raises awareness about the service, sacrifice and needs of military families. Obama, who filmed her guest spot Jan. 29 in Los Angeles, has also taped a public service announcement that will air during the episode. The Jessie cast will also join the Obamas at the White House Easter Egg Roll on April 21.

Jessie centers on 22-year-old Jessie Prescott (Debby Ryan) who, after spending her childhood on military bases, is now a New York City nanny to four children -- three of whom were adopted from different parts of the world -- and their giant pet lizard, Mrs. Kipling.

The official logline for the episode, "From the White House to Our House," is as follows: Jessie and Zuri (Skai Jackson) set out to host a birthday party for Taylor (Kyla Drew Simmons), a new friend who's sorely missing her mother, a deployed member of the military. When Taylor decides she'd rather not celebrate anything without her mother, Zuri enlists the help of Obama.

Last year, Obama was a keynote speaker at Disney's Veterans Institute, an event which leveraged the success of Disney's Heroes Work Here commitment to hire veterans and encourage better employment opportunities for military men and women transitioning into the civilian world. Joining Forces was launched by Obama and Dr. Jill Biden in 2011.