Stomach cancer survivor Roy Arredondo says he’s learned a lot during the past 5 years about dealing with cancer as a young adult. “My life changed dramatically,” said Arredondo. “I was depressed, I was scared, I was angry, and I felt like a failure to my family.”

Tobacco use remains the single largest preventable cause of disease and premature death in the United States. People have used many different methods to quit. Here is what the research tells us about how well they work: