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Mississippi Department of Transportation cameras showed a significant backup of vehicles, as emergency crews tended to the injured and wreckers worked to clear the scene. Ice kept the roadway closed overnight.

Officials said 27 vehicles were involved in the wreck, which was one of dozens in South Mississippi in just a few hours' time.

The bridge is located near the intersection of I-10 and Mississippi State Highway 603, which leads to Waveland.

Temperatures rose above freezing early Saturday, allowing for the reopening of the heavily traveled stretch of highway. Live camera images are available at the MDOT website.

In a separate accident on the Boley Creek Bridge in Pearl River Country, authorities say three people died.