Too bad the game still doesn't run at a stable 60 FPS for me sadly. The moment I try to use Stealth, it gets a massive drop in frames. Even with this GPU and CPU I can't get it above 40~45 FPS when that happens lol. #killergame. Guess I'll just have to play without Stealth, as that's the only way to retain 60 FPS.

In regards to the slowness, personally I think it's an issue with how the game (PCSX2) handles stealth somehow. The slowdowns literally only occur when the Stealth armor is equipped. (When you see that optic 'Predator-style' camouflage effect). It doesn't matter what resolution I use, the moment it's equipped, FPS takes a dip.

Just wondering, does this occur in sons of liberty aswell? It might be coded just differently even if its almost the same game.

Theres a pc version of substance, the version i played on a 9600xt/amd 2100 back in 2003 with no slowdowns. If you can use your controller with that game (assume you have one, otherwise why pcsx2 )
There should be a way to play it in whatever res/wudescreen.