He generally opposed government regulation and he became vilified by liberal academics for his work. He described how colleagues at the University of Virginia:[2]

...thought the work we were doing was disreputable. They thought of us as right-wing extremists. My wife was at a cocktail party and heard me described as someone to the right of the John Birch Society. There was a great antagonism in the '50s and '60s to anyone who saw any advantage in a market system or in a nonregulated or relatively economically free system.

Coase received some vindication by the scientific establishment when he was the sole recipient of the Sveriges Riksbank Prize in Economic Sciences in Memory of Alfred Nobel in 1991 for his theorem. In addition to his theorem, Coase also criticized licensing of the radio spectrum, and wrote a paper "The Federal Communications Commission" (1959) proposing that property rights is a more efficient method of allocating the electromagnetic spectrum.

Reason magazine published an enlightening interview of Coase in the late 1990s.[3]