Stealth RNAi™ siRNAs are highly potent, specific, and stable siRNA duplexes that are particularly suited for in vivo applications. This protocol describes the in vivo delivery of Stealth RNAi™ siRNA to mouse brain using an osmotic minipump.

SiRNA is widely used for analyzing gene function and target validation in vitro and in recent years has been successfully extended to in vivo research. Integrated DNA Technologies (IDT) synthesizes siRNAs for both in vitro and in vivo applications.

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