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Our experience has shown that a combination of synergistic agents within a medication class combined with appropriate target classes of medication offers the most beneficial product. For example, low back pain often consists of mechanical inflammatory pain associated with significant muscle spasm and neuropathic pain. Therefore, a good compound may consist of 2 different NSAIDS with slightly different MOA, 2 different muscle relaxers of different MOA, 2 different neuropathic agents, and a pain blocking agent combined with an anesthetic.