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Doesn't have driver support in macOS. It is really designed for Windows gaming, so I wouldn't expect either AMD or Apple to have this on a shortlist of priorities, especially since Apple is now using its own Metal II API which could presumably complicate getting it working with macOS.

I believe that Maxwell cards did have driver support for G-Sync at one point in macOS - don't know if it still works in El Capitan or Sierra/High Sierra though.