Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

From a technical perspective, OSUR spiked sharply higher here right off its 50-day moving average of $5.98 with strong upside volume. This stock has been trending sideways for the last month and change, with shares moving between $5.72 on the downside and $6.69 on the upside. Shares of OSUR are now starting to spike higher and move within range of triggering a breakout trade above the upper-end of its sideways trading chart pattern. That breakout will hit if OSUR manages to take out some near-term overhead resistance levels at $6.69 to $6.70 with high volume.

Traders should now look for long-biased trades in OSUR as long as it's trending above Thursday's low of $5.90 or above more support at $5.72 and then once it sustains a move or close above those breakout levels with volume that hits near or above 520,143 shares. If that breakout hits soon, then OSUR will set up to re-test or possibly take out its next major overhead resistance levels at $7.50 to $8.

RealD

RealD (RLD) is a licensor of 3D technologies. This stock closed up 1.4% to $7.04 in Thursday's trading session.

Thursday's Range: $6.94-$7.11

52-Week Range: $6.19-$16.05

Thursday's Volume: 402,000

Three-Month Average Volume: 467,389

From a technical perspective, RLD trended modestly higher here right above some near-term support at $6.83 with decent upside volume. This move is starting to push shares of RLD within range of triggering a near-term breakout trade. That trade will hit if RLD manages to take out its 50-day moving average of $7.18, and then once it clear more near-term overhead resistance at $7.20 to $7.56 with high volume.

Traders should now look for long-biased trades in RLD as long as it's trending above near-term support at $6.83 or at $6.19 and then once it sustains a move or close above those breakout levels with volume that hits near or above 467,389 shares. If that breakout hits soon, then RLD will set up to re-test or possibly take out its next major overhead resistance levels at $8.26 to $9. Any high-volume move above $9 will then give RLD a chance to tag $11 to $12.

Axcelis Technologies

Axcelis Technologies (ACLS) designs, manufactures and services ion implantation, dry strip and other processing equipment used in the fabrication of semiconductor chips in the U.S., Europe and Asia. This stock closed up 3.1% to $2.33 in Thursday's trading session.

Thursday's Range: $2.30-$2.42

52-Week Range: $0.82-$2.48

Thursday's Volume: 1.32 million

Three-Month Average Volume: 667,714

From a technical perspective, ACLS spiked sharply higher here right above its 50-day moving average of $2.23 with strong upside volume. This stock has been uptrending very strong for the last six months, with shares ripping higher from its low of $1.27 to its recent high of $2.48. During that uptrend, shares of ACLS have been consistently making higher lows and higher highs, which is bullish technical price action. That move has now pushed shares of ACLS within range of triggering a near-term breakout trade. That trade will hit if ACLS manages to clear Thursday's high of $2.42 to its 52-week high at $2.48 with high volume.

Traders should now look for long-biased trades in ACLS as long as it's trending above its 50-day at $2.23 or above more support at $2.05 and then once it sustains a move or close above those breakout levels with volume that hits near or above 1.32 million shares. If that breakout triggers soon, then ALCS will set up to enter new 52-week-high territory, which is bullish technical price action. Some possible upside targets off that move are $3 to $4.

At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Delafield, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including CNBC.com and Forbes.com. You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.