Hi everyone, I’m pretty new to this site does anybody have any experience with BAT? I was just approved by Hopkins. I have been fighting this disease for 10 years. Gleason score of 4+4. It has been biochemical recurrence without evidence of metastatic disease until two years ago started Zytiga and it is just now stopped working. Any experience with BAT would be helpful. God bless you all!

I just had my first injection of testosterone on January 12! I will keep you all informed. My PSA is currently 14. I had expected it to be somewhere around 40 as the Zytiga stopped working however the doubling time has slowed. I can explain why. When I started the Zytiga about a year and a half ago my PSA was 238. During that time, The PSA went down to 0.8.

I'm 58 and based in London. Having been diagnosed with Metastasis to Lymphs two years ago, I'm on quarterly ADT injections, and thankfully my PSA remains low. I turned down the offer of early chemo, as I wish to avoid.

When my PCa progresses to next stage, and becomes castrate resistant, the current NHS protocol is chemo. I'm obviously hoping for an immunotherapy breakthrough by then, and will consider overseas as self funding, but I'm also tempted to give BAT a try. Seems like the only way is to look at a clinic that offers male HRT - any thoughts?

Hi Paul I have a very similar diagnosis and will also be visiting an immunotherapy therapy clinic in Germany. BAT is also of great interest to me, my oncologist is looking at immunotherapy for me and telling me at what stage I should go for it. I will keep you up to date. 👍

I saw no men respond who are doing BAT---but I know of 2 on this site that have not responded to you. They are doing well. Hopkins results of their last stage test showed a high number of men having a 50% reduction in PSA, with quality of life improvements, from the high T,at 28 day intervals.

I am in discussion now with my Prostate Oncology Group at the Levine Cancer Institute--a lot of prostate medco's are following the Hopkins testing. I will be scheduled to go to Hopkins the first quarter of 18---to discuss adding T or doing BAT---though I am not castrate resistant. This group I am in, has not been tested for the ability of T to be of benefit. It is used with men who have failed a number of treatment modalities, and are castrate resistant.

My question to my Prostate Oncologist, is why not consider men before resistance--he said , that he will set me up at Hopkins, and anything they say as a possibility using T straight up or as in BAT--he would approve, if a Doc. at Hopkins says---take a shot.

I am castrate resistant which is the reason I’m willing to take a chance on this progressive therapy. I’ve talk to them about this prior to becoming castrate resistant and everyone has said to me not to consider it until the Zytiga stops working which it has.

That was the old thinking--which is not too old---Demeade who is running the trials at J. Hopkins, has said on a 2 hour video presentation---what about those who are not yet castrate resistant----is there a T benefit---and we may do some trials on this leg of the journey. I understand, why they may entertain this kind of trial, and the thinking's---which are those with low T before diagnosis, are more likely when getting Pca--to get an agressive form. And 25% of men with low T with good PSA numbers will get Pca, period.

So since all Doctors I know, and I have been studying TRT for years, as I started TRT in 1994---and went till my Diagnosis 2 years ago---all say T does not cause Pca. Having low T is more likely---So if my T was always high did I get Pca from my TRT supplementation. Answer is no----as the general thinking is that even though you have kept your T high, that the body considers itself low T, even though by blood test it is high T, This dichotomy, has not been figured out---with researchers investigating for 20 years, not coin up with a plausible theory.

Read some of pjoshea's writings here on T, BAT, Low T---etc. we are both kind of the non-professional consumers of knowledge on this subject. Notice I did not say Doctors or Experts. I was doing 5-Alpha Reductase drugs, and Aromatase Inhibitors since they were discovered to alter DHT and E2 formation. So I have been aware for 15 years before my Diagnosis, that I was a candidate for Pca, because of my low T. And the day came and it was my turn. I stopped T when I was Diagnosed---but it is under consideration--as all my Docs. think my burden is low now---and with an Undetectable PSA for 22 months--it is time for me to take some action--and not let it get castrate resistant. So we will see what the next 6 weeks will bring---right now lets all enjoy the holidays.

Been on the testosterone treatment protocol for three weeks. My strength has increased significantly in the weight room. But I don’t feel like Superman and I will not have any results from bone or CAT scans until 90 days. That’s the latest

I recently conversed with Ed Friedman about BAT and his views were below. I respect Ed very much, I've always completely concurred with his findings on prostate cancer, ever since reading his book about 4 years ago.

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They currently alternate high T with low T During low T, iAR amplifies and

high T then results in a drop in PSA (for ~50% of their patients). They repeat

the cycling of low T, then high T each month, but as the months go by, the

benefit from the high T becomes less and less. Once the benefit is almost

gone, they should be switching to high T plus 5AR inhibitors.

Another protocol which nobody has tried, but which should be effective is high

T plus an iAR inhibitor, such as enzalutamide. In theory, this combination

should be extremely effective in patients who initially received benefits from

Thank you for sharing this information. I’ve gone through my first weekend since receiving the testosterone shot. Been exercising twice today and while I have exercised even when I was on a low testosterone regimen, every muscle in my body hurts as if I had an exercise at all. Anyway no real adverse side effects for now

I kept my weight down and I exercised. For many years, approximately six years, Lupron kept me in check. And when it failed Two years ago I went on Zytiga. Unfortunately the testosterone study that I have been participating in has failed. My PSA rose in three months from 14 to 91. A recent scan shows the tumor is showing up in my lymph glands. So I am beginning to look at some other trials and trying to take care of myself. God’s will be done!

Have you thought about Dr. Kwon? and surgery to remove them or radiation.

How about getting a gene profile for possible immunotherapy.

I am 2 years post surgery -- gleason 8 -- psa currently 0.4

They found 4 of 10 lymph nodes with cancer at time of surgery. psa post surgery was 0.03 All I have done so far is Avadart and supplements. Any advise is appreciated. I have been trying to avoid lupron because that just starts the clock running to crpc.

I took the Lupron for about six years. I am not familiar with Dr. Kwon? I have found that I have a chek2 mutation. I don’t think I can irradiate them because I had salvage radiation eight years ago after the prostatectomy.

I kept my weight down and I exercised. For many years, approximately six years, Lupron kept me in check. And when it failed Two years ago I went on Zytiga. Unfortunately the testosterone study that I have been participating in has failed. My PSA rose in three months from 14 to 91. A recent scan shows the tumor is showing up in my lymph glands. So I am beginning to look at some other trials and trying to take care of myself. God’s will be done!