Michael Appleton took over the job, and led Leicester to a 2-1 victory over Swansea City. But while Shakespeare was the second managerial casualty of the season, he may be joined shortly by three others.

Everton, which had aspirations of a top-four finish heading into the season, was drubbed 5-2 by Arsenal Sunday, shipping three goals late after Idrissa Gueye saw red in the 68th minute.

The Toffees sit in 18th place after nine matches, and Ronald Koeman has to be on borrowed time. With a mid-week Carabao Cup match against Chelsea looming, could a loss spell the end of Koeman's reign?

In front of a record Premier League crowd of 80,827 people, Tottenham ran Liverpool off the Wembley pitch, with a comprehensive 4-1 victory.

Three first half goals from the Hotspurs front three of Harry Kane, Son Heung-Min, and Dele Alli gave the hosts a 3-1 lead at the break. Kane, who scored his league-leading eighth goal in the second half to ice the contest, led Tottenham up to third in the table, behind Manchester City and Manchester United.

City sits five points ahead at the top, with eight wins and a draw from its nine games. The Cityzens look like a team that could win the league by February, as their rampant attack continues to pile in the goals.

Can any team stop City from running away with the title?

HUGE WEEK FOR ENGLISH TEAMS IN EUROPE

With another massive week of UEFA matches in the books, the English sides, bar Everton, all look likely to progress through to the knockout stages of the Champions League and Europa League tournaments.

The Fubo.tv Premier League Match of the Week pits two of the top three teams in the league, as Tottenham travels to Manchester United for the early Saturday kickoff (7:30 a.m. EDT, NBC Sports and Fubo.tv) to get the action going next weekend.

The Red Devils come in off a first league loss of the season, 2-1 to Hudderfield, while Tottenham destroyed Liverpool 4-1.

Paul Pogba and Eric Bailly could return for United. Pogba has been out since September 12, and with Marouane Fellaini injured as well, the Manchester United midfield has struggled to make the same impact.