Abortion and subsequent maternal death rates: Second of 2 new studies from Denmark

http://eurpub.oxfordjournals.org/content/early/2012/09/05/eurpub.cks107.abstracthttp://afterabortion.org/2012/multiple-abortions-increase-risk-of-maternal-death-new-study/ Coleman PK, Reardon DC, Calhoun BC. Reproductive history patterns and long-term mortality rates: a Danish, population-based record linkage study Eur J Public Health, first published online September 5, 2012 Dr. Coleman’s summary See more info at: http://www.wecareexperts.org/content/second-study-using-danish-population-data-led-wecare-director-published-european-journal-pub The general purpose of this more extensive study was to explore the effects of particular patterns of pregnancy resolution (induced abortion, miscarriage, and birth) on mortality rates over an extended time frame (25 years). Specifically examined were: 1) detrimental and/or protective effects of distinct forms of pregnancy resolution over time; 2) detrimental and/or protective effects of distinct forms of pregnancy resolution occurring repeatedly over time; and 3) elevated or attenuated mortality risks when distinct pregnancy outcomes were combined with other forms of pregnancy resolution. As we note in the article “The primary strengths of the study are the use of large scale population level data that includes reliable records on all possible reproductive outcomes and prospectively gathered data from different birth cohorts of women. The results of comprehensive studies of this nature offer more accurate information regarding mortality risks associated with reproductive outcomes than the data acquired by governmental agencies relying on information primarily garnered from death certificates.” The results indicated the following: 1) With controls for the number of pregnancies, year of birth, and age at last pregnancy, having experienced only induced abortion(s) and natural loss(es) was associated with over 3 times the risk of death from all causes compared to only having experienced birth(s). 2) Risk of death was over 6 times greater among women who had never been pregnant compared to those in the birth(s) only group. 3) Compared to a reproductive history that only included births, after instituting controls, increased risk of death were as follows: only induced abortion(s): 66%; only natural loss(es): 181%; all reproductive outcomes 94%. 4) Compared to no experience of abortion, increased mortality risks after applying controls were evidenced for the following: one abortion: 45% increased risk; two abortions: 114% increased risk; and three abortions: 191% increased risk of death. 5) Significantly decreased mortality risks were evidenced with multiple births: 2 births were associated with an 83% lower risk of death compared to no births and 3 or more births corresponded to a 44% decreased risk over no births. 6) Increased risks of death were equal to 44%, 86%, and 150% for 1, 2, and 3 natural losses respectively compared to no natural losses. Key points (from the end of the article): 1) This study offers more accurate information regarding mortality risks associated with reproductive outcomes than the data acquired by death certificates. 2) Distinct patterns of reproductive outcomes involving induced abortion, spontaneous abortion and birth across a 25 year window are associated with different levels of risk of dying. 3) Mortality risks associated with induced abortion and spontaneous abortion are more pronounced when more than one is experienced. Dr. Reardon’s summary Multiple Abortions Increase Risk of Maternal Death Springfield, IL (September 7, 2012) — A single induced abortion increases the risk of maternal death by 45 percent compared to women with no history of abortion, according to a new study of all women of reproductive age in Denmark over a 25 year period. In addition, each additional abortion is associated with an even higher death rate. Women who had two abortions were 114 percent more likely to die during the period examined, and women had three or more abortions had a 192 percent increased risk of death. Elevated rates of death were also observed among women who experienced miscarriages, ectopic pregnancies or other natural losses. Women with a history of successful deliveries were the least likely to die during the 25 years examined. Women who had never been pregnant had the highest mortality rate. Among women with a history of multiple pregnancies, women with a history of both abortions and natural losses, but no live births, had the highest mortality rate. The study is the second record linkage analysis of Danish mortality data to be published this month. The earlier study was limited to comparing mortality rates following only the first pregnancy outcome. It found that abortion of a first pregnancy was associated with a higher rate of death compared to death rates among women who delivered a first pregnancy. The higher death rate among women who had abortions persisted for each of the first ten years following the first pregnancy outcome. “Dose Effect” Supports Causal Link The finding that each additional abortion or other pregnancy loss contributed to a rising death rate is an indication that the observed effects are more likely to be causal than incidental, according to Dr. David Reardon, one of the co-authors of both studies. “We knew from our previous studies of low income women in California that women who have multiple pregnancy outcomes, such as having a history of both abortion and miscarriage, have significantly different mortality rates,” Reardon said. “But this new study is the first to examine how each experience with abortion or miscarriage contributes to higher mortality rates.” This is called a “dose effect” because “each exposure, or ‘dose,’ is seen to produce more of the same effect, which is what one would expect if there is a cause-effect relationship,” Reardon explained. Reardon is the director of the Elliot Institute, which funds research related to abortion. He believes further research is needed to explore how the outcomes observed in this latest study may be influenced by abortion’s impact on natural pregnancy losses. A new population study from Finland, for example, has found that abortion is associated with higher rates of preterm delivery, low birth weight delivery, and perinatal deaths in subsequent pregnancies. Reardon believes that a truer picture of the benefits of childbirth and the risks of abortion and pregnancy loss is now emerging because of a shift to more reliable record linkage studies. Such studies have been conducted in Finland, Denmark and the United States. Before these record linkage studies were available, efforts to compare the mortality rates associated with abortion and childbirth were usually based on death certificates alone. Reardon characterized those previous comparisons as “junk in, junk out” analyses because death certificates have been proven to be notoriously inaccurate in regard to women’s reproductive history, especially in regard to any history of abortion or miscarriage. “Record linkage studies are the only way to use the same objective yard stick for comparing mortality rates associated with pregnancy outcomes,” he said. “More researchers and more research dollars should be expended on investigating these issues. Without it, population control efforts in developing countries may lead to ill-informed public health initiatives which will actually increase death rates among women rather than reduce them.” Link to this article: http://eurpub.oxfordjournals.org/content/early/2012/09/05/eurpub.cks107.abstract See also: http://afterabortion.org/2012/multiple-abortions-increase-risk-of-maternal-death-new-study/ The Elliot Institute is dedicated to conducting original research on the impact of abortion on women and to promoting efforts to create a safe, healing environment for those struggling with a past abortion. Studies Referenced Coleman PK, Reardon DC, Calhoun BC. Reproductive history patterns and long-term mortality rates: a Danish, population-based record linkage study Eur J Public Health, first published online September 5, 2012 Reardon DC, Coleman PK. Short and long term mortality rates associated with first pregnancy outcome: Population register based study for Denmark 1980-2004. Med Sci Monit 2012;18(9):PH 71 – 76. Klemetti R, Gissler M, Niinimäki M, Hemminki E. Birth outcomes after induced abortion: a nationwide register-based study of first births in Finland. Hum Reprod 2012 Aug 29. [Epub ahead of print]