Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Additionally we are shipping MAST2 Kits (5) and MAST2 Proteins (4) and many more products for this protein.

MAST205 plays an important role in regulating CFTR (show CFTR Antibodies) expression and function

The MAST2 sequence at the 5' end of SVA(F1) acts as a positive transcriptional regulator in human germ cells.

Overexpression of MAST1 (show MAST1 Antibodies) or MAST2 gene fusions has a proliferative effect both in vitro and in vivo in breast cancer cell lines.

Recruitment of a MAST2 CpG island was most likely beneficial to the hybrid retrotransposons because it could significantly increase retrotransposition frequency.

Studies report the identification of a new subfamily of SVA, which apparently formed after an alternative splicing event where the first exon of the MAST2 gene spliced into an intronic SVA and subsequently retrotransposed.

MAST2 Antigen Profile

Protein Summary

Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation.