Antiwrinkle Shots Spark Debate

By

Rhonda L. Rundle

Updated Oct. 31, 2006 12:01 a.m. ET

Artes Medical Inc. said it received U.S. Food and Drug Administration approval to market the cosmetic injectable ArteFill for treating wrinkles running from the nose to the corners of the mouth. The product has stirred controversy because it stays in the body permanently, unlike other antiwrinkle shots that wear off after four to six months.

ArteFill is administered in a physician's office and typically requires 15 to 30 minutes. The experience for patients is similar to that of injectable temporary dermal fillers,...