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Billy along with Rebecca are played simultaneously and are the only playable characters in Resident Evil Zero. Billy will differ from Rebecca in that he can not mix Herbs however, he is not in need of health items as much because he has much more health. Billy also has a better chance at achieving headshots and can fire magnums faster as he doesn't flinch from the recoil like Rebecca. Puzzle wise, Billy is stronger and will be able to push heavier objects and he weighs more which will play a part in some puzzles. Billy is also able to play the piano. His personal item is the Lighter, which is required for some puzzles. When Billy joined Rebecca early in the game, he will have the following items;

Billy is a playable character in Resident Evil: The Umbrella Chronicles . Him along with Rebecca are playable for the for the "Train Derailment" scenario. His handgun is just called the "Handgun". His melee attack is first pushing the zombie away then delivering a dropkick.

Billy is one of ten new character cards in the Resident Evil DBG expansion Alliance.

Billy's card in Alliance

He has 80 Health. Billy's Level 1 effect allows him to gain one "Ammo x10" and gives him an additional Buy. His Level 2 effect allows him to move a card from his Discard Pile to his hand, but only if he has 10 or more cards in the pile. Interestingly enough, Billy's abilities go hand-in-hand with Rebeccas as the game progresses (of course they would both have to be present in Partner Mode). The "Ammo x10" cards that Billy gains can easily be trashed by Rebecca once they become less useful. And their mutual abilities to take cards away from the Discard Pile makes them a great combination if the player wishes to trim down his or her Inventory to the essentials. Of course this may be deliberate on the part of the game designers since Billy and Rebecca were the protagonists of Resident Evil Zero. His pose is his selection portrait in Umbrella Chronicles.