In the diploma thesis, a method for preparation of the unsaturated C15-C20 tiacumicin fragment was developed. Tiacumicin is classified as a macrolidone antibiotic. Although three syntheses of tiacumicin have been recently ...

This thesis deals with an enantioselective synthesis of cyclic compounds by using a combination of organocatalysis and transition metal catalysis. The thesis deals mainly with usage of aminocatalyst for activation of ...

This work is divided into two parts that are focused on the synthesis and assessment of photophysical properties of two structurally related compounds: (i) 9,9'-spirobifluorenes (SBFs) and (ii) dispiroindeno[2,1-c]fluorenes ...

diploma thesis

Author: Vašíček, Tomáš

Advisor: Matoušová, Eliška

Date Issued:

Date of defense: 29. 05. 2018

Faculty / Institute: Přírodovědecká fakulta / Faculty of Science

Abstract: In this diploma Thesis, a method for the preparation of polycarbocyclic compounds containing all-carbon quaternary centers embedded in triquinane skeleton was prepared. The key reaction sequence leading towards the preparation ...

This work consists of four consecutive parts, each dealing with syntheses of structurally diverse compounds. The syntheses were based on the methods within the domain of transition-metal catalyzed and/or mediated reactions ...

Gold catalysis has recently experienced a sustained upswing in interest from scientific community. The amount of new reactions catalysed by gold is so significant that little is known about mechanisms of most of these ...

This bachelor thesis is focused on the new preparation procedure of the unsaturated actinofuranone fragment JBIR-108 which was isolated from actinobacteria Streptomyces gramineu. This exotoxin appears to be cytotoxic to ...

Vývoj nových syntéz kondenzovaných aromatických sloučenin

rigorous thesis

Author: Kaiser, Reinhard Peter

Date Issued:

Date of defense: 20. 05. 2019

Faculty / Institute: Přírodovědecká fakulta / Faculty of Science

Abstract: This work is divided into two parts that are focused on the synthesis and assessment of photophysical properties of two structurally related compounds: (i) 9,9'-spirobifluorenes (SBFs) and (ii) dispiroindeno[2,1-c]fluorenes ...

Za dodržení všech ustanovení autorského zákona jsou zodpovědné jednotlivé složky Univerzity Karlovy. / Each constituent part of Charles University is responsible for adherence to all provisions of the copyright law.

Upozornění / Notice: Získané informace nemohou být použity k výdělečným účelům nebo vydávány za studijní, vědeckou nebo jinou tvůrčí činnost jiné osoby než autora. / Any retrieved information shall not be used for any commercial purposes or claimed as results of studying, scientific or any other creative activities of any person other than the author.

Za dodržení všech ustanovení autorského zákona jsou zodpovědné jednotlivé složky Univerzity Karlovy. / Each constituent part of Charles University is responsible for adherence to all provisions of the copyright law.

Upozornění / Notice: Získané informace nemohou být použity k výdělečným účelům nebo vydávány za studijní, vědeckou nebo jinou tvůrčí činnost jiné osoby než autora. / Any retrieved information shall not be used for any commercial purposes or claimed as results of studying, scientific or any other creative activities of any person other than the author.