FAQs

Why should I use LentiFlash® instead of transfection reagents ?

Transfection reagents are commonly used to transiently transfer RNA in cells of interest. However, these reagents may impact the cell viability, lead to high cell toxicity and can modify the cell phenotype (when used on difficult to transfect cells). LentiFlash, an RNA delivery particle derived from lentiviral vectors, resolves these main drawbacks.

Why the use of LentiFlash® is recommended for gene editing ?

Gene editing using CRISPR-Cas9 system is widely used nowadays, but it has been shown that a stable expression of CRISPR-Cas9 into cells of interest may lead to off-target activity which results in unexpected genome modifications. For this reason, we advise scientists to use LentiFlash for gene editing experiments (for transient RNA delivery).