Von Eeden was born in Guyana[1] and moved to New York City when he was 11 years old.[1] According to Von Eeden, he remembers drawing in his early teens in order to alleviate the boredom of junior high school, beginning with anatomical studies of faces and hands, which he says are the most difficult things to draw accurately, in the margins of his notebooks. He was introduced to comics through the collection of his best friend.[2] Influences included Neal Adams, John Buscema, and Curt Swan.[3] Von Eeden's best friend encouraged him to submit sample artwork to DC Comics;[2] at the same time, Von Eeden was studying medicine at Columbia University.[3]

About three years later, Von Eeden began to suspect he had gotten that job because of his skin color, which displeased him and resulted in his writing what he called a five-page mission statement that said "in detail exactly what I wanted to create — the kind of style I thought would express myself most effectively, while also telling a story in the most dramatic way possible. I wrote everything down that I could think of — the details, form, and purpose of the style of art that I'd wanted to create."[2]

In 1977, he began drawing the "Green Arrow" backup feature in World's Finest Comics[5] and co-created the Count Vertigo character with Gerry Conway in World's Finest Comics #251 (July 1978). Von Eeden recalled in a 2011 interview that he "worked for Neal [Adams] concurrent with my DC tenure—starting in 1978, until somewhere in the late '90s".[6] He moved to Marvel Comics in 1979 and 1980 and pencilled Power Man and Iron Fist and Spider-Woman.[7] His stint at Marvel Comics was cut short because, in his own words, he was "fired by Jim Shooter, who’d told me specifically, when I’d first started there, to try and draw like Jack Kirby—and apparently wasn’t happy that I didn’t."[8] He then returned to DC and once again drew the "Green Arrow" feature in World's Finest Comics[5] and later in Detective Comics as well.[9] In collaboration with writer Mike W. Barr, he crafted Batman Annual #8 (1982)[10] and a Green Arrow miniseries.[11] Von Eeden has noted that the Batman Annual is "the book I’m most proud of, in my 25 year career at DC Comics. I was able to ink it myself, and also got my girlfriend at the time, Lynn Varley, to colour it – her first job in comics."[12] He and writer Jack C. Harris proposed to DC an all-female superteam named the Power Squad, but were turned down.[13] In 1983, Von Eeden and writer Robert Loren Fleming created the DC series Thriller, an action-adventure story that allowed him room to experiment.[14][15] Von Eeden left the series as of its eighth issue due to difficulties with DC Comics' management.[16] He stated in a 2017 interview that he was "thrilled beyond measure" that Thriller is "the one job of my entire 41-year career that the fans have fondly and consistently remembered since it first appeared."[17]

"Venom", the fourth story arc in the Batman: Legends of the Dark Knight series, was drawn by Von Eeden, Russell Braun, and José Luis García-López.[7][19] Von Eeden drew a Black Canary limited series (Nov. 1991-Feb. 1992) as well as an ongoing series featuring the character in 1992–1993.[7] In a 2009 interview he stated that ''Black Canary, on the other hand, was done in one state of mind, from beginning to end, one of semi-interest, to tell you the truth. I didn't, and still don't, find her to be a particularly interesting character."[20]

In 2001 Von Eeden returned to Batman, penciling the five-issue storyline "Grimm" in Batman: Legends of the Dark Knight #149–153.[21] He also illustrated a series of short stories, "Joe In The Future", published in Heavy Metal #v25 #6 (Jan. 2002) and #v27 #5 (Nov. 2003)[1]

In 2007 Von Eeden began writing and drawing The Original Johnson, a biography of the boxer Jack Johnson. The 242-page graphic novel was serialized in weekly online installments at ComicMix, and was completed in 2009.[14] Print rights to the book were acquired by IDW Publishing, who issued the series as a two-volume set in 2010 and 2011.[1] He has called this project "The other 'most satisfying' book of my career (aside from the Batman Annual #8) is The Original Johnson – the first book I’ve ever written and drawn."[12]

He provided illustrations for the text story "The Holo-Marketeer" for Heavy Metal #v34 #9 (Jan. 2011) and designed and illustrated superhero comics produced for the National Hockey League by Stan Lee.[1] He later drew four issues of Gateway Comics' Stalker.[22]

^ abcVon Eeden, Trevor (2009). "Booom". Trevorvoneeden.com. Archived from the original on February 4, 2013. Retrieved October 19, 2011. About three years into my career, at about the age of 20, I started to feel that I'd only gotten the job because of my skin color—a notion which displeased me greatly.

^Manning, Matthew K. "1980s" in Dolan, p. 199: "Green Arrow netted the coveted position as back-up story to the Dark Knight's adventures in Detective Comics. Written by Joey Cavalieri, with art by Trevor Von Eeden, the new feature saw Star City's renowned archer renew his war on crime."

^Manning "1990s" in Dougall, p. 191: "The strength-enhancing drug that would later help villain Bane defeat Batman debuted in this five-issue arc written by Dennis O'Neil and drawn by Trevor Von Eeden and Russell Braun."