Bone has an obvious mechanical function as well as it serves an equally important role as mineral reservoir. Bone remodeling is continuous, dynamic and lifelong phenomenon i.e. its inner structure and shape keep changing constantly in a well concert with normal variation in mechanical function and mineral exchange. Any disruption in this interactive system leads to various orthopedic and bone metabolic disorders. Osteomalacia, the most common bone disorder is mainly caused by mineralization loss and reduced availability of vitamin D.