Cultivation Systems

The claims and demands on cell culture systems capturing the complexity of in vivo tissue concerning composition and stability in relation to toxicological issues require the provision of reproducible cell populations for studying the toxic profile of substances even with differentiated cells. For that purpose, identical cell cultures are required for repeatable experiments. Thus, automated cell cultivation systems are highly desirable for in vitro toxicology as the handling of cell cultures is a laborious work and vulnerable to person-specific variations as well as pipetting errors. The CULTEX® Long Term Cultivation (LTC) system was specifically designed for the computer-controlled cultivation of cells (up to 24 cell culture inserts) that are grown on commercial cell culture inserts under ALI conditions for weeks.