Borussia Dortmund stunned new and old champion Bayern Munich 3-0 in the Bundesliga on Saturday to remain alone in second place. It was Bayern’s biggest loss under coach Pep Guardiola.

Henrikh Mkhitaryan scored in the 20th and Marco Reus and Jonas Hofmann added goals after the break as Bayern lost its second straight game in the Bundesliga without scoring a goal. Bayern is winless since clinching the title with a record seven matches to play.

Rafinha was sent off in injury time for grabbing the face of Mkhitaryan and Bayern and Germany goalkeeper Manuel Neuer did not return for the second half with a calf injury. He was replaced by Lukas Raeder, who made his Bundesliga debut. Mkhitaryan scored after being found by Reus in the box.

Reus was set up by Pierre-Emerick Aubameyang and Hofmann collected a long pass to bury the shot past the helpless Raeder. Typically, Bayern dominated the stats, retaining 71 percent posession while registering 15 attempts on goal, as opposed to Dortmund’s nine. Bayern also completed 570 passes, while Dortmund had a meagre 164 passes among them. Still, Dortmund was the more clinical team of the two.

“We tried to win the ball close to their goal and we managed to do that and we used our chances. We attacked very well,” Reus said. Bayern was coming off a 3-1 win over Manchester United for a place in the semifinals in the Champions League, while Dortmund was eliminated by Real Madrid, Bayern’s next opponent.

Both Bayern and Dortmund have German Cup semifinal games midweek but fielded most of their stars, with the exception of Dortmund striker Robert Lewandowski, who came on during the second half. Dortmund is 17 points behind Bayern but three points ahead of Schalke.

In other matches, Freiburg improved its chances of avoiding relegation while hurting those of Eintracht Braunschweig with a 2-0 victory. Nuremberg also had a setback by going down 4-1 at Wolfsburg, which moved up to fourth.

Hamburger SV lost 2-1 at Hannover and remained in the danger zone, while Stuttgart clinched a 1-1 draw at Borussia Moenchengladbach, which fell behind Wolfsburg to fifth. Mainz beat Werder Bremen 3-0.