Archive -
08 - 2006

August 28, 2006 (Eurekalert) - As schools across the country reopen their doors this fall, hundreds of sixth graders in 42 middle schools will begin taking part in a study sponsored by the National Institutes of Health (NIH). The HEALTHY study will determine if changes in school food services and physical education (PE) classes, along with activities that encourage healthy behaviors, lower risk factors for type 2 diabetes, an increasingly common disease in youth."The alarming rise in obesity and type 2 diabetes in all age groups poses a major public health crisis for this country. This important study is one component of a multi-faceted research agenda to address this dual epidemic, which threatens the health of our youth and the vitality of our health care system," said NIH Director Elias A. Zerhouni, M.D.Participating schools will be randomly assigned to a program group, which implements the changes, or to a comparison group, which continues to offer food choices and PE programs typically seen in middle schools across the country. Students in the program group will have * healthier choices from the cafeteria and vending machines (e.g., lower fat foods, more fruits and vegetables, and drinks with no added sugar) * longer, more intense periods of physical activity, and * activities and awareness campaigns that promote long-term healthy behaviors.After 2.5 years, all students will be tested for diabetes risk factors, including blood levels of glucose, insulin, and lipids. They will also be measured for fitness level, blood pressure, height, weight, and waist circumference."The school environment can have a profound effect on the behavior and health of young people. From this study we hope to learn if better food options, improvements in physical activity programs, and education about eating better and moving more result in healthier kids and a lower risk of type 2 diabetes," said study chair Gary Foster, Ph.D., of Temple University. The study is being conducted by researchers at * Baylor College of Medicine, Houston, TX * University of California at Irvine, CA * University of North Carolina at Chapel Hill, NC * Oregon Health and Science University, Portland, OR * Temple University, Philadelphia, PA * University of Pittsburgh Medical Center, Pittsburgh, PA * University of Texas Health Science Center at San Antonio, TX * George Washington University, Washington, D.C. (Coordinating Center)In planning the HEALTHY study, researchers relied on the results of six pilot studies. In one such study, about half of eighth graders in 12 schools were overweight or at risk for overweight. Few had diabetes, but about 41 percent had abnormally high readings of fasting blood glucose, pointing to a much higher risk of developing type 2 diabetes.Type 2 diabetes is closely linked to being overweight, inactive, and having a family history of diabetes. Nearly two-thirds of U.S. adults are overweight or obese, with a body mass index (BMI) of 25 or more. Among youth 2 to 19 years old, 17 percent are overweight (i.e., have a BMI at the 95th percentile or more for their age and sex) -- triple the rate in 1980. About the same percentage of youth have a BMI between the 85th and 95th percentile for their age and sex, putting them at risk for becoming overweight.Type 1 diabetes, which affects up to 1 million people in the United States, develops when the body's immune system destroys the insulin-producing beta cells of the pancreas. This form of diabetes usually strikes children and young adults, who need several insulin injections a day or an insulin pump to survive. The HEALTHY study is aimed at preventing type 2 diabetes. Other NIH-funded studies are trying to prevent type 1 diabetes in centers nationwide: http://www.nih.gov/news/pr/jun2006/niddk-09.htm.The longer a person has diabetes, the greater the chances of developing serious damage to the eyes, nerves, heart, kidneys, and blood vessels. "We're already seeing kids in their late teens with early complications from type 2 diabetes," said Francine Kaufman, M.D., director of the Comprehensive Childhood Diabetes Center at the Childrens Hospital Los Angeles, where type 2 diabetes accounts for more than 20 percent of new childhood diabetes cases. "As a society, we need to address the obesity epidemic if we're going to have any success containing the rising rate of type 2 diabetes in kids. A logical place to start is in our schools."Once seen only in adults, type 2 diabetes has been rising steadily in youth. While there are no national data on the prevalence of type 2 diabetes in youth, clinics around the country are reporting that more young people, especially from minority groups, are developing the disease. Studies in Cincinnati, Los Angeles, San Antonio, and other cities conclude that cases of type 2 diabetes in youth have risen dramatically since 1994, when less than 5 percent of new childhood diabetes cases were type 2. By 1999, type 2 diabetes accounted for 8 to 45 percent of new childhood diabetes cases, varying by geographic location. Some diabetes centers are now seeing more new cases of type 2 diabetes than type 1.Nearly 21 million people in the United States -- 7 percent of the population -- have diabetes, the most common cause of blindness, kidney failure, and amputations in adults and a major cause of heart disease and stroke. Type 2 diabetes accounts for up to 95 percent of all diabetes cases in adults, and about one-third of those affected don't know they have it. The prevalence of type 2 diabetes has risen dramatically in the last 30 years, due mostly to the upsurge in obesity. In addition, at least 54 million U.S. adults age 20 and older have pre-diabetes, which independently raises the risk of developing type 2 diabetes and cardiovascular disease.Results from the HEALTHY study are expected in 2009. Sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the study is part of a broad research initiative, called STOPP T2D (Studies to Treat or Prevent Pediatric Type 2 Diabetes), which seeks to improve the treatment and prevention of type 2 diabetes in youth. The American Diabetes Association (ADA) co-sponsors the HEALTHY study, and the Institute for Public Health and Water Research supports the study through a grant to the ADA.

ALEXANDRIA, Va., Aug 25, 2006 (PRNewswire via COMTEX) - Whether you're trying to prevent diabetes, better manage your disease or slow complications from developing, the American Diabetes Association (ADA) has developed specific guidelines to help you choose the right meal plan to get you to your goals.Published in the September issue of Diabetes Care, the ADA's revised medical nutrition therapy recommendations update statements published in 2002 and 2004 using the most recent scientific data available. For the first time, the guidelines categorize medical nutrition advice according to a person's medical condition, breaking out recommendations for people at high risk for diabetes; managing existing diabetes; and trying to prevent or slow the rate of development of diabetes complications. Specific recommendations are also included for people with type 1 diabetes, pregnant or nursing mothers with diabetes, older adults, and those living in long-term care facilities or managing acute illnesses such as kidney disease."When you're talking about diabetes, there is no 'one size fits all' diet," said Ann Albright, PhD, RD, President-Elect, Health Care & Education, American Diabetes Association. "For people with diabetes and those at risk for type 2 diabetes, medical nutrition therapy should be tailored to a person's specific health issues and personal preferences to help maintain optimum health by controlling blood glucose levels, blood pressure, cholesterol, and other risk factors. We hope these recommendations will help people make better choices about what they eat and how they live to maximize their chances of staying healthy."The recommendations emphasize the importance of sustained, moderate weight loss for people who are overweight or obese and increased physical activity for all people at risk for or living with diabetes. They also pointedly ask people with diabetes to avoid fad diets, such as those that promote extreme low-carbohydrate or high-protein intake."There is no evidence that these diets are successful at helping people keep weight off once they lose it, and there are ample concerns about the fiber, vitamins, and minerals people give up when they severely restrict their diet, say by sharply limiting carbohydrate intake," said Dr. Albright. "Fad diets come and go. We want people to be provided with sound nutrition advice that will help them in making choices for maintaining good health for the long term."For people who are at risk for diabetes, the guidelines call for a diet high in fiber and nutrient-rich foods (14 grams of fiber for every 1,000 calories), with whole grains making up half of all grain intake. In emphasizing the importance of weight loss, they note that medications may be useful for some individuals if combined with lifestyle changes, and that for the very obese, weight loss surgery has shown considerable health benefits. They also caution people who use meal replacements to lose weight that research finds the weight loss is only maintained as long as people stay on the meal replacement plan. Exercise is recommended independent of weight loss because studies show it helps lower blood glucose levels, increases insulin sensitivity, and improves cardiovascular risk factors regardless of whether the person loses any weight.For people who already have diabetes, the nutrition guidelines are more specific. They include carbohydrates from fruits, vegetables, whole grains, legumes and low-fat milk; eating fiber-rich foods; keeping saturated fats to less than 7 percent of total caloric intake; eating at least two servings of non-fried fish per week; limiting trans fats; and restricting cholesterol intake to less than 200 mg/day.The recommendations note that there is no evidence that type 1 diabetes can be prevented through medical nutrition therapy. They also caution that, while there is not yet sufficient evidence to include guidelines for children at risk for or living with type 2 diabetes, it is reasonable to assume the same general advice given to adults would benefit children. Studies looking specifically at how medical nutrition therapy affects children are currently underway.Diabetes Care, published by the American Diabetes Association, is the leading peer-reviewed journal of clinical research into the nation's fifth leading cause of death by disease. Diabetes also is a leading cause of heart disease and stroke, as well as the leading cause of adult blindness, kidney failure, and non-traumatic amputations. For more information about diabetes, visit the American Diabetes Association Web site http://www.diabetes.org or call 1-800-DIABETES (1-800-342-2383).