@article{Kunitake1992BindingOT,
title={Binding of transition metals by apolipoprotein A-I-containing plasma lipoproteins: inhibition of oxidation of low density lipoproteins.},
author={Steven T Kunitake and Michael R. Jarvis and Robert L. Hamilton and John P. Kane},
journal={Proceedings of the National Academy of Sciences of the United States of America},
year={1992},
volume={89 15},
pages={6993-7}
}

We have found transition metals tightly bound to apolipoprotein A-I-containing lipoproteins [Lp(A-I)] isolated by selected affinity immunosorption from human serum. Prominent among the metal ions detected were iron and copper. By immunoblotting the proteins of Lp(A-I), we detected both transferrin and ceruloplasmin. The transferrin-containing Lp(A-I) particles, isolated by selected affinity immunosorption against transferrin, were larger (mean diameter of 14.2 nm) and had a higher protein… CONTINUE READING