The life of teenage Peter Parker is changed forever after he is bitten by a radioactive spider and given powers. He becomes a hero named Spider-Man after the death of his Uncle Ben and he must adapt to this new way of life.

The first season of "Hulk and the Agents of S.M.A.S.H" is based on the superhero character by Marvel Comics. Hulk, She Hulk, Red Hulk, A Bomb, and Skaar come together as the Agents of S.M.A.S.H. The Agents of S.M.A.S.H. have their base near the town of Vista Verde and often face various threats with a recurring one being from Hulk';s archenemy the Leader. The Hulk and Rick Jones respond to a gamma portal from the Negative Zone created by Annihilus in an effort to drain Earth';s resources. But unable to get through, Annihilus sends a mind-controlled Skaar to retrieve a Gamma ray cannon to help him push through.

In this season, The Incredible Hulk teams up with his cousin She-Hulk, A-Bomb, Red Hulk and Skaar, Marve to battle the forces of evil in front of cameras for Rick's web-based series to show the Hulk is more hero than monster.

For ages, Loki the trickster has sought a way to bring defeat to his accursed stepbrother, Thor. But for all the battles Thor has fought, in all the nine realms, only one creature has ever been able to match his strength, a mortal beast of Midgard known as The Incredible Hulk.