Definition

Primary pulmonary hypertension (PPH) is a rare disease. It is high blood pressure
in the blood vessels of the lungs.

A person with PPH has extra muscle in the walls of these blood vessels. That extra muscle makes it more difficult for blood to flow through them. As a result, the right side of the heart has to work harder to push blood to the lungs. This additional strain can eventually lead to heart failure.

Causes

The cause of PPH is unknown. Several factors may contribute to the development of the disease, including:

Immune system disease

Exposure to certain drugs or chemicals

Genetic defects

Risk Factors

The following factors increase your chances of developing PPH:

Female between the ages of 30 and 40

Liver cirrhosis

Portal hypertension

HIV infection

Family history of PPH

Use of appetite suppressants—diet drugs (eg, fenfluramine)

Cocaine use

Symptoms

Initial symptoms of PPH may be minor. They will get progressively worse. If you experience any of these symptoms do not assume it is due to PPH. These symptoms may be caused by other, less serious health conditions. If you experience any one of them, see your doctor.

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY.
Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.