Combines glucosamine, a natural component found in connective tissues and joint cartilage with chondroitin and MSM.

Glucosamine and chondroitin provide many benefits:

Supports the body's natural ability to support joint tissue/function*

Helps rebuild cartilage and lubricate joints*

Support the body's ability to support joint health integrity*

Supports the body's natural ability to regenerate cartilage*

In addition to Glucosamine and Chondroitin this highly effective product also contains 25 mg of Lignisul MSM™ Methylsulfonyl-methane which is an organic sulfur found within connective tissues and joint cartilage.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement Facts

As a dietary supplement for adults, take one soft chew two to three times a day, preferably with meals.

Storage Instructions: To ensure freshness, reseal container after each use.

Store at room temperature(55-85 degrees F.

Warning: After opening, keep tightly closed in refrigerator or other cool place.

Contains: Crustaceans (shrimp)

This product contains ingredients derived from milk and soy.

Contains peanuts.

Lignisul MSM™ is licensed according to US Patents. Every shipment is tested by third-party laboratories to ensure purity and high-quality.

Health Notes

Disclaimer:
This scientific independent research is provided by Aisle7 and is for informational use only. GNC provides this information as a service but does not endorse it. Likewise, Aisle7 does not recommend or endorse any specific products.

For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

Dose: 2.25 to 6.0 grams per dayIn one trial, supplementing with methyl-sulfonylmethane significantly reduced pain and improved overall physical functioning in patients with osteoarthritis of the knee. (more)

Chondroitin sulfate (CS) is a major component of the lining of joints. The structure of CS includes molecules related to glucosamine sulfate. CS levels have been reported to be reduced in joint cartilage affected by osteoarthritis. Possibly as a result, CS supplementation may help restore joint function in people with osteoarthritis.1 On the basis of preliminary evidence, researchers had believed that oral CS was not absorbed in humans;2 as a result, early double-blind CS research was done mostly by giving injections.3, 4 This research documented clinical benefits from CS injections. It now appears, however, that a significant amount of CS is absorbable in humans,5 though dissolving CS in water leads to better absorption than swallowing whole pills.6

Strong clinical evidence now supports the use of oral CS supplements for osteoarthritis. Many double-blind trials have shown that CS supplementation consistently reduces pain, increases joint mobility, and/or shows evidence (including X-ray changes) of healing within joints of people with osteoarthritis.7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17 Most trials have used 400 mg of CS taken two to three times per day. One trial found that taking the full daily amount (1,200 mg) at one time was as effective as taking 400 mg three times per day.18 Reduction in symptoms typically occurs within several months.

Dose: 2.25 to 6.0 grams per dayAccording to a small double-blind trial, 2,250 mg per day of oral methylsulfonylmethane (MSM), a variant of DMSO, reduced osteoarthritis pain after six weeks.1 In another double-blind trial, supplementation with 3 grams of MSM twice a day for 12 weeks significantly reduced pain and improved overall physical functioning in patients with osteoarthritis of the knee.2

Dose: Refer to label instructionsA few trials have evaluated glucosamine hydrochloride (GH), another form of glucosamine sulfate (GS), as a single remedy for osteoarthritis. One trial found only minor benefits from 1,500 mg per day of GH for 8 weeks in people with osteoarthritis of the knee.1 However, these people were also taking up to 4,000 mg per day of acetaminophen for pain relief, and that treatment might have masked a beneficial effect of GH. In another study, supplementing with GH (2,000 mg each morning for 12 weeks) significantly improved symptoms, compared with a placebo, in people with knee pain due to cartilage damage or osteoarthritis.2 In a four-week study from China, GH was as effective as GS in people with osteoarthritis of the knee.3 Another study found that the combination of GH and chondroitin sulfate was more effective than a placebo in people with moderate to severe knee pain from osteoarthritis, but not in those with mild pain.4 Despite the reported beneficial effects of GH, some investigators believe that the sulfate component of GS itself helps relieve osteoarthritis, and that GS would therefore be more effective than GH.5

The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2015.

Label

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This is a good product, but has one of the worst shipping delays and time I have ever seen from any online product, if you want this im a timely fashion do yourself a favor and go to the store personally, if you're waiting for it to be shipped to you, expect anywhere from a week to 2 weeks time. If you buy online expect a LONG delay, if you expect it sooner, then do yourself a favor and go to a store personally.

I bought these after using another brand of glucosamine/chondroitin in pill form. I had many of the side effects except nausea. So I decided I should try the chews as they are easier on the stomach. I've taken them twice now & really like. They taste like a Werthers in chew form. I bought for fibromyalgia symptoms & knee pain after surgery a few yrs ago. Dr said I have early arthritis. I was nervous about trying this flavor because of some reviews but they aren't bad.

In this form TriFlex is delicious. It's like having a candy to finish off a meal, but it is also beneficial. I think it works just as well as taking TriFlex in pill form, if not better. In this form I have more confidence that it is being quickly absorbed. I eat one after every meal (3 a day)

A friend recommended this brand and I saw that a chewable was offered so I decided to give it a try. The 1st taste was okay but it does have an after taste. Not a bad product though and I would buy it again.