Help Fight Muscular DystrophyMission:To investigate protein-protein interactions for more than 2,200 proteins whose structures are known, with particular focus on those proteins that play a role in neuromuscular diseases.

Help Fight Childhood CancerMission:The mission of the Help Fight Childhood Cancer project is to find drugs that can disable three particular proteins associated with neuroblastoma, one of the most frequently occurring solid tumors in children.

Help Conquer Cancer.Mission:To improve the results of protein X-ray crystallography in order to increase understanding of cancer and its treatment.

Human Proteome FoldingMission:The two main objectives of the project are to: 1) obtain higher resolution structures for specific human proteins and pathogen proteins and 2) further explore the limits of protein structure prediction by further developing Rosetta software structure prediction.

FightAIDS@HomeMission:To study computational ways to design new anti-HIV drugs based on molecular structure