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| Graphic

Bone Marrow Biopsy

Section of bone marrow core biopsies showing the marrow structure and various components of the marrow. In the normal bone marrow (left), the trabecular bone (thick arrow) and the fat cells (thin arrows) through which the hematopoietic cells percolate can be seen. In the biopsy from a patient with leukemia (right), the fat cells and the normal marrow cells have been replaced by the leukemic cells, which appear darker because of their large nuclei.