Researchers conducted a meta-analysis to examined possible links between antidepressant use and epithelial ovarian cancer, and links between duration and intensity of antidepressant use and risk for epithelial ovarian cancer.

Ovarian cancer risk is known to be increased by BRCA1 and BRCA2 gene mutations, but recent developments have led researchers to believe there are several genes involved in homologous recombination-mediated DNA damage.