Molecular and Metabolic Evidence for Mitochondrial Defects Associated With β-Cell Dysfunction in a Mouse Model of Type 2 Diabetes

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIG. 7.

Summary of the molecular and protein expression changes that lead to the dysfunctional metabolic phenotype in diabetic MKR
islets. The proteins highlighted in red were significantly changed in MKR diabetic islets.