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Mouse Anti-CD44 DNA-encoded mAb (Clone CBWJC-1444), pVAX1

DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics. This product is the plasmid containing an encoded Mouse anti-CD44 DMAb (Clone CBWJC-1444) sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

Specifications

Target

CD44

Target Species

Human

DMAb Host

Mouse

DMAb Cross Reactivity

Human

DMAb Isotype

IgG1, κ

DMAb Clone

CBWJC-1444

Vector Name

pVAX1

Vector Description

pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter

CMV

Vector Tag or Fusion

Untagged

Delivery Method

Transfection

Cloning Method

Restriction Enzyme ⁄ MCS

Constitutive or Inducible System

Constitutive

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Target

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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