Two female mental patients chained in the back of a county sheriff's van drowned when the vehicle in which they were traveling was overcome by floodwaters, police said.

They were about halfway through the trip by 6 p.m., on Highway 76 near the Little Pee Dee River, when the van encountered the running water. At this time, the recovery effort is ongoing, and the transportation vehicle can not be removed due to rising waters and unsafe conditions.

"Tonight's incident is a tragedy", said Horry County Sheriff Phillip Thompson, according to local reports.

The river stands at more than 14 feet and is expected to reach 15.6 feet by Thursday night.

Richardson said the patients' bodies were being recovered Wednesday morning.

Or northbound motorists from Georgia could get off I-95 and take either I-26 or I-20 to Columbia and then catch I-77 to Charlotte, the agency said.

Horry County Deputy Tom Fox told WPDE-TV the victims were mental health patients being transported from one facility to another. Holden wouldn't give further details on the victims' status, citing an ongoing state police investigation.

The incident is being investigated by the State Law Enforcement Division. By the time they got there, the van was underwater, and the deputies were on the roof.

"Once those orders are issued, we don't place those people in a detention centre", Thompson said. Thompson said neither deputy had committed any significant past driving infractions in connection with their duties.

In a Wednesday night press conference, Thompson was asked whether or not the deputies had driven around barriers on the flooded road. The two officers involved have been placed on administrative leave.

Speaking to the Associated Press, Marion County Coroner Jerry Richardson said, "They're both still under the water". "People need to know exactly how it happened. It makes it seem like someone took a very unnecessary risk". Compounding the problem, storm runoff from North Carolina - which was battered by Florence - is now flowing through the Palmetto State via the Yadkin-Pee Dee drainage basin, which terminates in Winyah Bay near Georgetown, S.C.

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