Police said the motorcyclist and a passenger were taken to a local hospital and then flown to Dartmouth-Hitchcock Medical Center. The driver of the tractor-trailer was taken to Franklin Regional Hospital.

Police said the accident happened about 9 a.m. near Holy Cross Drive. Investigators said it's still too soon to know exactly what happened.

"Right now, the whole thing is under investigation, but as near as we can tell, the motorcycle was heading southbound, and the truck was heading northbound," Chief David Goldstein said.

It's not clear if the people on the motorcycle were wearing helmets at the time of the crash.