Multidrug-resistant Acinetobactor baumannii isolated from a traveler returned from Brunei.

Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan; Disease Control and Prevention Center, Japan; Department of Infectious Diseases, Research Institute, Japan.

2

Disease Control and Prevention Center, Japan.

3

Disease Control and Prevention Center, Japan; Department of Infectious Diseases, Research Institute, Japan.

4

Department of Infectious Diseases, Research Institute, Japan.

5

Department of Clinical Laboratory, Japan.

6

Infection Control and Prevention, National Center for Global Health and Medicine, Tokyo, Japan.

Abstract

We report a case of multidrug-resistant (MDR) Acinetobactor baumannii isolates obtained from a traveler returned from Brunei. Whole-genome sequencing analysis revealed that the isolates harbored blaOxA-23 and armA. The minimum inhibitory concentrations of antibiotics against the strain were as follows: imipenem, 32 μg/ml; meropenem, 32 μg/ml; ciprofloxacin, 16 μg/ml; amikacin, ≧ 1024 μg/ml; arbekacin, ≧ 1024 μg/ml; aztreonam, 64 μg/ml; colistin, 4 μg/ml. A. baumannii harboring both blaOxA-23 and armA is rarely reported in Japan, and, to the best of our knowledge, this is the second report of A. baumannii harboring both resistant genes in Japan.