The finalists for this year's TV Breakthrough Performance were scenes from Gossip Girl, True Blood, and Grey's Anatomy. The winner, as voted by the fans, was the scene from True Blood where Bill Compton meets waitress Sookie Stackhouse for the first time.

Goof: Neil Patrick Harris misread the teleprompter when he said award presenter Tina Fey did additional voices for Deer Hunter 2: Deer in the City. The 1999 video game is entitled Deer Avengers 2: Deer in the City.

During the clips of "The Best of the Year in Comedy", they showed a scene from the pilot of Scrubs ("My First Day") which aired 8 years ago. However, that clip was shown in a flashback sequence in the season 8 episode "My Finale: Part 1".

Amy Poehler: A best supporting actor or actress award is a tough one to win. The word 'rigged' is mentioned a lot. Basically, it's the one category that can be bought.Julia Louis-Dreyfus: It's expensive, but it's worth it.

Jon Cryer: (accepting his award) I used to think that uh, awards were just shallow tokens of momentary popularity, but now... I realize they are the only true measure of a person's real worth as a human being.

Dearbhla Walsh: Finally, I want to uh, thank my partner for your patience, your love, your support. For watching the cuts and giving me notes. And it looks like it's the three of us in the bed tonight. (raises her trophy)

(accepting the award for Outstanding Original Music & Lyrics)Rob Schrab: I'd like to thank my mom and dad and our girlfriends.Dan Harmon: Nerd alert! You see what I'm telling you? Just the dumbest, dumbest, ugliest people. The least televise-able you have ever given this award to.

This year, the "Breakthrough Performance of the Year" category is introduced, wherein television fans can log online (via TV.com) and choose their favorite among 15 performances. The top three vote-getters are revealed during the show's telecast, during which TV viewers decide who ultimately wins the award.

Allusions

NPH was referring to Kanye West's recent infamous meltdown at the Video Music Awards 2009 when he stormed the stage, interrupted Taylor Swift's acceptance speech, and announced that Beyonce deserved the award for Best Female Video.

Toni Collette: (on her baby daughter) ...wondering why it was a strange man breastfeeding her at three months of age.

Collette weaned her daughter Sage during the production of United States of Tara, where she plays a mother afflicted with Dissociative Identity Disorder. One of her alters (alter egos) on the show is Buck, a male Vietnam war veteran.

Rob Lowe was considered for the role of Dr. Derek Shepherd (played by Patrick Dempsey) on the highly popular medical drama Grey's Anatomy but chose to produce and star in his own show, the short-lived comedy Dr. Vegas.

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