I'm a pharmacist. Actually acetaminophen alone is Preg Cat B - it has been tested in pregnancy and it's okay but you should still tell your doc if you want to take it. Tylenol PM contains acetaminophen and diphenhydramine (Benadryl). Diphenhydramine is also pregnancy category B, so it should be no problem to take Tylenol PM, but I would just let your doctor know.

As a nurse with several years of experience in OBGYN, all three practices that I have worked for all have Tylenol and Tylenol pm as &quot;safe to use during pregnancy&quot; on the list of medications we gave all of our new patients. Of course, **you should check with your OB and see how he/she feels about it for you!! ** All manufactured medications received a Pregnancy Category rating A-D and X. A is obviously the best but usually only reserved for components of prenatal vitamins. B indicates that it has been tested in pregnancy and no evidence of causing birth defects or problems. C is where a lot of medicines fall (including Tylenol) b/c most pregnant women don't want to find out if a certain medication causes problems or not. &quot;Although studies have not been done in pregnant women, acetaminophen (Tylenol) has not been reported to cause birth defects or other problems&quot; (Drugs.com) but b/c it has not been tested receives a Cat C. Bottom line: check with your doc but it's *likely* ok.

My doctor told me that it was safe and recommended it to me as I was working so many hors standing and walking alot. He said it was safer to take at night as it makes you tired but thats when I feel my aches the most. I was also told that I could take benadryl for my allergies and I take that at night sometimes too.

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