Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.

Form Supplied

Liquid

Concentration

Batch dependent
mg/ml
(Please refer to the vial label for the specific concentration)

Purification

Protein A purified, followed by peptide affinity purification.

Specifications: UNC5C antibody, Internal

Full Name

unc-5 homolog C (C. elegans)

Background

This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq]