A major part of the preparations in this group are combined preparations. Preparations containing e.g. analgesics and antispasmodics could be classified either in this group or in N02 - Analgesics. Combinations of psycholeptics and antispasmodics could be classified in A03 or in N05 - Psycholeptics etc. The main indication for the use of the combination will, together with the relative effect of the active components, decide the classification. In the treatment of pain caused by spasms, the spasmolytic component must be judged as more important than the analgesic component. Accordingly, analgesic/antispasmodic combinations should be classified in A03 if the main effect of the preparation is the antispasmodic action.

Combined preparations are classified in:A03C - Antispasmodics in combination with psycholepticsA03D - Antispasmodics in combination with analgesicsA03E - Antispasmodics and anticholinergics in combination with other drugs

Antispasmodics, which are used specifically in the urogenital tractus, are classified in G04BD - Drugs for urinary frequency and incontinence.

The DDD for the substances is usually equal for different routes of administration (oral, parenteral or rectal) of the same compound and is based on the oral dose.

Plain preparations for systemic use containing glycopyrronium bromide are classified in this group. Preparations containing glycopyrronium in combination with neostigmine are classified in N07AA51. Trospium see G04BD and A03DA.Pipenzolate in combination with silicones is classified in A03AB14.

The parenteral DDD for glycopyrronium bromide is based on the use as premedication for anesthetic procedures.