“I think it is devastating to the administration and to perceptions of President Obama’s leadership. It would validate concerns that he is not governing from the center.”

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“If the Court strikes the entire law, it will invalidate the signature achievement of the Obama administration. It may incite a backlash among supporters, but that will not be enough to make up for the loss of the law.”

Small win for Republicans

“Most of this issue has played out long ago, particularly in the 2010 cycle. It’s a GOP talking point, not a game change.”

“The devil is really in the details—for both the Democrats and the Republicans. How far does the Court go?”

“Republicans will have won bragging rights, and that certainly counts for something.”

“Don’t kid yourself—there’s no way you can put a smiley face on a loss.”

Neither party gains

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“GOP win would translate to loss for millions of Americans deprived of adequate health care. It reopens the whole raucous debate.”

“It all depends on the spin. I hope the administration does better with a do-over.”

Small win for Democrats

“It will fire up the Democratic base, but it probably won’t move the needle with independents all that much one way or the other.”

Big win for Democrats

“It will galvanize the Democratic base to run against the Republican Court and Republican Congress.”

What will the political ramifications be if the Supreme Court strikes down all or part of the president’s health care law?