I should have taken the tests next week when my 2 girls and I is going to the vet.

When I receive the results and I'll publish it :smile:

I think Coco maybe has the bad CCS gene cause her father has it.

Some others who have tested their dogs ?

sins

30th June 2011, 08:09 PM

Hi Torben,
One of mine has been tested and is genetically clear.
I'll test the youngest later in the year.
You don't need the vet to take the sample,it's easy to do !
Good luck with the result,hopefully your beautiful girl has not inherited a copy of the mutation.
Sins

Nicki

30th June 2011, 08:34 PM

Good luck with the testing Torben - I hope to have one of my girls tested later in the year.

Great news about Holly, Sins :D

GreenDenmark

30th June 2011, 08:52 PM

You don't need the vet to take the sample,it's easy to do !
Sins

I know it's easy to take the sample, but the vet have to sign the test in Denmark so it can be registered in the Danish CKCS club which is FCI.

sins

30th June 2011, 09:04 PM

Ok, I didn't know the Danish Club had a register!
Sins

GreenDenmark

30th June 2011, 09:23 PM

They started the first test about 1st. January

There er 71 dog tested now.
12 with CCS (1 dead)
11 is BH
1 TRI.

18 with EFS (4 is ill)
10 is BT
3 is BH
5 is RB

Margaret C

30th June 2011, 11:51 PM

They started the first test about 1st. January

There er 71 dog tested now.
12 with CCS (1 dead)
11 is BH
1 TRI.

18 with EFS (4 is ill)
10 is BT
3 is BH
5 is RB

On June 2nd Tania and I went to a health seminar at the Animal Health Trust, where they developed this DNA test.

There was a talk by Catherine Mellersh on Canine Genetics and Inherited Disease & we were shown a slide that said that 165 cavaliers had been tested for CC and EF since it was officially launched in the UK on April 18th.

Then they showed how many of those were UK dogs.........16

There was a footnote that said that a recent test for late onset PRA ( an eye condition ) in Gordon Setters had resulted in 240 UK dogs being DNA tested in 78 days.

I have had Faith DNA tested for CC & EFS
For £48 it seemed commonsense to make sure that I was not spending so much time and money trying to get her in whelp only to find the puppies were affected by a preventable condition.

It was done by my vet simply so that I could show her microchip number had been independently checked when the swabs were taken.

I'm pleased to say that she is clear of both conditions

Karlin

1st July 2011, 12:27 AM

Then they showed how many of those were UK dogs.........16

:sl*p:

For a test originating in the UK? I wonder how many on the health committee and cavalier club committees? Some of these people have over the years expressed distress to many pet owners on email lists and boards over their cavaliers with CCS and EFS and talked about how terrible it is for breeders to find they have bred CCS puppies as they immediately put them down. And about how badly breeders in this breed need some definite genetic tests. Now they have some for some truly horrible diseases that are exclusive to cavaliers. Dr Jacques Penderis says given research work and tests on dogs over several years -- and he is the leading expert -- he considers EFS to be a COMMON gene in the breed and more common as a symptomatic condition in cavaliers than epilepsy.

Surely these people, who I could name and expect are very likely NOT on that list, the club and especially individual health reps should be giving extremely strong public support to these tests and demonstrating by example and testing all their own dogs?

Surely it is better to spend £48 ONE TIME per breeding dog, rather than pay the same amount to kill puppies you have bred? Or find you have dogs of your breeding suffering with these conditions? If club breeders will not do this wonderful test to eliminate definitely any chance of breeding dogs with these genes, then tell me how they are any different from puppy farmers? :confused: They are knowingly choosing to dice with painful and in the case of CCS eventually fatal, horrific conditions that could be prevented for the price of, what -- a tank of petrol for driving to a dog show? A couple of show entries? A cheap hotel room for a show for one night? A single large bag of dog food?

Margaret C

1st July 2011, 12:41 AM

we were shown a slide that said that 165 cavaliers had been tested for CC and EF since it was officially launched in the UK on April 18th.

Then they showed how many of those were UK dogs.........16

There was a footnote that said that a recent test for late onset PRA ( an eye condition ) in Gordon Setters had resulted in 240 UK dogs being DNA tested in 78 days.

To put it in context........8154 cavaliers were registered with the UK Kennel Club in 2010.

306 Gordon Setters were registered in 2010.

What is even more impressive is that the Gordon Setter PRA test results are recorded and published on the KC registration papers for all to see.

Nicki

1st July 2011, 10:08 AM

I have had Faith DNA tested for CC & EFS
For £48 it seemed commonsense to make sure that I was not spending so much time and money trying to get her in whelp only to find the puppies were affected by a preventable condition.

It was done by my vet simply so that I could show her microchip number had been independently checked when the swabs were taken.

I'm pleased to say that she is clear of both conditions

That is just fantastic news Margaret, I'm so thrilled for you :thmbsup:

I think it's an absolute tragedy that only 16 dogs have been tested in the UK - as Karlin says, breeders have been demanding genetic tests for years, this isn't even that expensive, there is no stress to the dog, it would seem to be the answer they have been looking for...

I guess their reaction will be "not another test" :mad:

Sadly I don't think those poor puppies would be taken to the vets to be PTS - but that's another topic entirely and we won't go there :(

Why is it that breeders of other breeds are so much more concerned about health issues? they seem to really care about the future of their breeds, about their dogs suffering - we have one of the most loving, happiest breeds in the World, and yet they have the misfortune to be in this culture of only caring about what's winning in the show ring and money from puppy sales.

I do realise that obviously other breeds are also bred at puppy farms, and there are many out there who only care about money, but the club members should be leading from the front setting an example - so that puppy buyers who approach them realise that the dogs should be tested - if they then choose to go elsewhere, maybe they will ask if they are health tested and not fobbed off with "well I've never seen that in my lines"

How many dogs have been mated in the time since the test has been available - and only 16 have been tested, not all of those will have been bred...

Margaret C

1st July 2011, 11:59 AM

This is also a test that will be useful for vets, as it will confirm if dogs are affected with the syndromes.
Especially useful for those cavaliers that have collapsing symptoms.

Although most Curly Coat/Dry Eye puppies are identified and PTS at a very young age there does seem to be a few cavaliers that are not obviously affected from the time they open their eyes, and so do enter the puppy market.

These puppies usually still have a sparse 'brillo pad' coat but do not develop the really painful dry eye until they are slightly older.

sunshinekisses

1st July 2011, 02:41 PM

Torben-good luck on your results.

Has anyone fromt the U.S. had the test done? I have tried to order but keep receiving errors. Congrats on those having the test done and recieving good results!

GreenDenmark

16th July 2011, 08:35 PM

Yesterday I've received the first result.

Luna is now CLEAR for Curly coat dry eve syndrome and for Episodic falling. :thmbsup:
I hope the result for Coco is coming at Monday.

Margaret C

16th July 2011, 10:05 PM

Yesterday I've received the first result.

Luna is now CLEAR for Curly coat dry eve syndrome and for Episodic falling. :thmbsup:
I hope the result for Coco is coming at Monday.

I'm so pleased for you.

I'll keep my fingers crossed for Coco:xfngr:

Jasper and Holly

17th July 2011, 03:57 AM

That's great news Torben. I hope Coco has the same good news. Fingers crossed!

ByFloSin

17th July 2011, 09:56 PM

I just thought you might be interested to know that before the Midland CKCS Club's Open Show started this morning an announcement was made that there are to be 20 free test facilities offered and to be paid for by the CKCS Club. Application forms were available at the show, to be returned to Peter Towse, who will select the recipients from the completed applications.

While making the announcement the seriousness of the two defects and the conditions they carry with them were outlined. Additionally, I offered to give any further information about CC/DE, it's symptoms and diagnosis to anyone who contacts me.

I don't think it fair to say that the clubs are doing nothing. My calculator tells me that 20 x £48 totals £960 worth of free testing. Rather more than nothing don't you think.

Margaret C

17th July 2011, 11:15 PM

A wonderful idea.

I presume that all Club members are going to be notified and given the chance of this free test?

It will of course be important that everyone has an equal chance to benefit from this new initiative and that the method used to choose the lucky applicants is completely unbiased and fair.
Do you know how this will be done?

Nicki

18th July 2011, 04:17 PM

Congratulations Torben on Luna's results - paws crossed for Coco too.

I'm thrilled that the club [Midland club or parent club?] are financing 20 tests, that's great news - unfortunately there doesn't seem to be any information on either the parent club or Midland club sites :confused:

Do you know any more information please Flo? There doesn't seem to be anything about it on a certain other forum either :?

Zumie05

19th July 2011, 03:21 AM

Is this test being recommended all Cavaliers take, or just breeding dogs? Just as how I eventually want Coco MRI'd I now want to have these DNA tests done as well...

GreenDenmark

26th July 2011, 08:56 PM

I got the result for Coco this evening and she is CLEAR too.
I'm so happy !!!

Margaret C

26th July 2011, 09:34 PM

I got the result for Coco this evening and she is CLEAR too.
I'm so happy !!!

I am so pleased for you. Very well done.

As I said earlier Faith was clear on the DNA tests and I had some other good news too. I recently had Faith scanned again at one of the Stonelion scanning days and at four years she is still Grade A.

She has CM, as do 98% or so of all cavaliers, but the scan is exactly the same as last time, with no SM, ventricular dilatation ( excess fluid within ventricles of the brain ) or PSOM. ( glue ear )

I had her rescanned as she was last MRI'd at 2.5 years and although she was then mated twice to an older grade A mate she failed to get into whelp. Tests eventually showed he was no longer fertile.

At least I still know that her scan is still as good as it gets for a cavalier before I introduce her to a new young SM clear mate.

Nicki

26th July 2011, 09:42 PM

Well HUGE congratulations to both of you :wggle::wggle::wggle:

What fantastic news :grin:

Torben I think you were suspicious of Coco's results, so this must be a huge relief for you.

Thank you both for carrying out these tests.

Margaret C

27th July 2011, 04:42 PM

I just thought you might be interested to know that before the Midland CKCS Club's Open Show started this morning an announcement was made that there are to be 20 free test facilities offered and to be paid for by the CKCS Club. Application forms were available at the show, to be returned to Peter Towse, who will select the recipients from the completed applications.

While making the announcement the seriousness of the two defects and the conditions they carry with them were outlined. Additionally, I offered to give any further information about CC/DE, it's symptoms and diagnosis to anyone who contacts me.

I don't think it fair to say that the clubs are doing nothing. My calculator tells me that 20 x £48 totals £960 worth of free testing. Rather more than nothing don't you think.

I see there is now a notice about this on the Cavalier Club website, but in fact none of the cavalier clubs are paying, this is a free offer from the Animal Health Trust to test 200 cavaliers, 20 from each regional club..............

"AHT investigation into frequencies of the mutations associated with dry eye curly coat syndrome and episodic falling in CKCS in the UK

In April 2011 the Animal Health Trust (AHT) was pleased to announce the launch of two new DNA tests for dry eye curly coat syndrome and episodic falling in CKCS. These tests have been made available as the result of genetic studies carried out at the Kennel Club Genetics Centre at the AHT. To assist CKCS breeders further, we are now gathering information about the frequency of these two mutations in the current UK population. This will entail the collection and testing of DNA from a random selection of CKCS of breeding age so that we can determine the percentage of dogs carrying the mutations.
The AHT propose collecting cheek swab samples from 200 individual dogs (20 from each of the ten regional breed clubs). Each dog will be tested free of charge for both conditions. Sampling dogs from all of the regional breed clubs provides a means of gathering data from a wide geographical area, and we would prefer that each of the 200 dogs tested has a different sire and dam to maximise the cross section of the CKCS population that we sample."

Nicki

27th July 2011, 06:58 PM

That is very generous of the Animal Health Trust - wouldn't it be wonderful if the clubs contributed too??

GreenDenmark

3rd August 2011, 10:13 AM

Well HUGE congratulations to both of you :wggle::wggle::wggle:

What fantastic news :grin:

Torben I think you were suspicious of Coco's results, so this must be a huge relief for you.

Thank you both for carrying out these tests.

Yes is right I were suspicious about Coco's results, and it's such a enormous relief :lotsaluv: