Fusion

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

glr2942

Single-stranded DNA-binding protein (121 aa)

Predicted Functional Partners:

glr2943

Nitrilase-like protein (270 aa)

0.866

ycf41

Hypothetical protein (150 aa)

0.834

dnaE

DNA polymerase III subunit alpha (1159 aa)

0.826

glr1609

DNA polymerase III gamma and tau subunits (632 aa)

0.825

glr2487

Single-stranded DNA-binding protein (118 aa)

0.804

rpsR

30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (74 aa)

0.801

uvrA

Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (981 aa)

Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA (809 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

dnaE

glr1609

gvip538

gvip228

DNA polymerase III subunit alpha

DNA polymerase III gamma and tau subunits

0.998

dnaE

glr2487

gvip538

glr2487

DNA polymerase III subunit alpha

Single-stranded DNA-binding protein

0.826

dnaE

glr2942

gvip538

glr2942

DNA polymerase III subunit alpha

Single-stranded DNA-binding protein

0.826

dnaE

polA

gvip538

gvip065

DNA polymerase III subunit alpha

DNA polymerase I

0.976

dnaE

uvrA

gvip538

gvip553

DNA polymerase III subunit alpha

Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate

0.422

dnaE

ycf41

gvip538

gvip045

DNA polymerase III subunit alpha

Hypothetical protein

0.826

glr1609

dnaE

gvip228

gvip538

DNA polymerase III gamma and tau subunits

DNA polymerase III subunit alpha

0.998

glr1609

glr2487

gvip228

glr2487

DNA polymerase III gamma and tau subunits

Single-stranded DNA-binding protein

0.825

glr1609

glr2942

gvip228

glr2942

DNA polymerase III gamma and tau subunits

Single-stranded DNA-binding protein

0.825

glr1609

polA

gvip228

gvip065

DNA polymerase III gamma and tau subunits

DNA polymerase I

0.898

glr1609

ycf41

gvip228

gvip045

DNA polymerase III gamma and tau subunits

Hypothetical protein

0.825

glr2487

dnaE

glr2487

gvip538

Single-stranded DNA-binding protein

DNA polymerase III subunit alpha

0.826

glr2487

glr1609

glr2487

gvip228

Single-stranded DNA-binding protein

DNA polymerase III gamma and tau subunits

0.825

glr2487

glr2942

glr2487

glr2942

Single-stranded DNA-binding protein

Single-stranded DNA-binding protein

0.804

glr2487

polA

glr2487

gvip065

Single-stranded DNA-binding protein

DNA polymerase I

0.804

glr2487

priA

glr2487

gll0025

Single-stranded DNA-binding protein

Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA

30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit

0.801

glr2487

uvrA

glr2487

gvip553

Single-stranded DNA-binding protein

Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate

0.790

glr2487

ycf41

glr2487

gvip045

Single-stranded DNA-binding protein

Hypothetical protein

0.834

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: