Mario Zanetti, 20, was born on 9 January 1892 at Poschiavo, Kanton Graubünden, Switzerland. Together with his friends Abele Rigozzi and Alessandro Pedrini he was employed by Luigi Gatti to sail on the Titanic, his first ship. At this time he lived at Cairo Café, 3 Soho Street, Oxford Street, London.

He signed-on on 6 April and began work on the Titanic on the same day. His wages were £2 2s per month (plus tip).

Zanetti died in the sinking. His body, if recovered, never was identified.

He left his 44 year old mother Margherita Zanetti-Mengotti, two brothers (21 and 22) and a sister (18). His mother lived in Geneva. White Star paid compensation of £50 and outstanding wages of sFr 10.60 to his mother. From the Lord Mayor's Fund she received £70. In the end his savings of 450.45 Swiss francs were paid to her.