XVI. References

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A syndrome characterized by dryness of the cornea and conjunctiva. It is usually caused by a deficiency in tear production. Symptoms include a feeling of burning eyes and a possible foreign body presence in the eye.

Definition (NCI_CTCAE)

A disorder characterized by dryness of the cornea and conjunctiva.

Definition (MSH)

Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur.

Ontology:
Sjogren's Syndrome
(C1527336)

A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood

Definition (CHV)

A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood

Definition (CHV)

A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood

Definition (CHV)

A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood

Definition (CHV)

A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood

Definition (CHV)

A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood

Definition (CHV)

A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood

Definition (CHV)

A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood

Definition (CHV)

A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood

Definition (MEDLINEPLUS)

Sjogren's syndrome is a disease that causes dryness in your mouth and eyes. It can also lead to dryness in other places that need moisture, such as your nose, throat and skin. Most people who get Sjogren's syndrome are older than 40. Nine of 10 are women. Sjogren's syndrome is sometimes linked to rheumatic problems such as rheumatoid arthritis.

Sjogren's syndrome is an autoimmune disease. If you have an autoimmune disease, your immune system, which is supposed to fight disease, mistakenly attacks parts of your own body. In Sjogren's syndrome, your immune system attacks the glands that make tears and saliva. It may also affect your joints, lungs, kidneys, blood vessels, digestive organs and nerves. The main symptoms are:

An autoimmune disorder affecting the salivary and lacrimal glands. Morphologically, it is characterized by the presence of lymphocytic and plasmacytic infiltrates which cause destruction of these glands. It results in dry mouth and dry eyes. It may be associated with the presence of other autoimmune disorders, including rheumatoid arthritis and lupus erythematosus.

Definition (NCI_NCI-GLOSS)

An autoimmune disease that affects the tear glands and salivary glands, and may affect glands in the stomach, pancreas, and intestines. The disease causes dry eyes and mouth, and may cause dryness in the nose, throat, air passages, skin, and vagina. It may also cause inflammation in the joints, muscles, and skin; pneumonia; tingling in the fingers and toes; and fatigue. It often occurs with rheumatoid arthritis or other connective tissue diseases.

Definition (MSH)

Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.

Definition (CSP)

symptom complex of unknown etiology, usually occurring in middle-aged or older women, marked by the triad of keratoconjunctivitis sicca with or without lacrimal gland enlargement, xerostomia with or without salivary gland enlargement, and the presence of a connective tissue disease, usually rheumatoid arthritis but sometimes systemic lupus erythematosus, scleroderma, or polymyositis; an abnormal immune response has been implicated.

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This page was written by Scott Moses, MD, last revised on 7/17/2009 and last published on 2/21/2018.