A Clinical Investigation to Evaluate the Healing of Tooth Extraction Sites Filled With BioRestore™

Summary

The aim of this study was to evaluate by histology and MSCT scans during a 7-month period,
the efficacy of a bioactive glass (Inion BioRestore™) placed in human extraction sockets in
the maintenance of alveolar ridge.

Description

14 subjects in need of implant therapy were enrolled in the study. A total of 32 teeth were
extracted and the fresh sockets underwent to ridge preservation procedures using Inion
BioRestore™. Two different time points (1 week and 3 months after RPP) MSCT scans for each
patient were used as a basis for bone change analysis occurred in the localized grafted
alveolar sites. Twenty-two biopsied, representative of intermediate (3-4 months, n=10) and
late phase (6-7 months, n=12) of healing, were harvested and histologically analysed.

Bone loss around tooth extraction sites can occur, thus making future placement of dental implants difficult. Alveolar bone regeneration can be guided by the application of a nanofibrous bone graft co...

The alveolar bone has a unique capacity to follow the teeth's movements. It is formed around erupting teeth and their periodontal ligaments: the more the teeth have erupted, the larger the alveolar pr...

This case report presents a novel approach towards the preservation of alveolar ridge dimensions following the extraction of an upper left lateral incisor. The extracted teeth of a 56-year old patient...

BACKGROUND The aim of this study was to dynamically evaluate tooth movement, root resorption, and remodeling of alveolar bone using different forces to cause tooth movement in rats. MATERIAL AND METHO...

To investigate the effect of local injection of receptor activator of nuclear factor kappa B ligand (RANKL) on experimental tooth movement and subsequent alveolar bone remodeling in mice.

Medical and Biotech [MESH] Definitions

Alveolar Bone Loss

Resorption or wasting of the tooth-supporting bone (ALVEOLAR PROCESS) in the MAXILLA or MANDIBLE.

Periodontal Ligament

The fibrous CONNECTIVE TISSUE surrounding the TOOTH ROOT, separating it from and attaching it to the alveolar bone (ALVEOLAR PROCESS).

Periodontium

The structures surrounding and supporting the tooth. Periodontium includes the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.

Alveolar Bone Grafting

Surgical procedure to add bone to the ALVEOLAR RIDGE in children born with a CLEFT LIP and a CLEFT PALATE.

Furcation Defects

Conditions in which a bifurcation or trifurcation of the molar tooth root becomes denuded as a result of periodontal disease. It may be followed by tooth mobility, temperature sensitivity, pain, and alveolar bone resorption.

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