Cryo-EM image analysis

The recovery of high resolution 3D information from a set of noisy 2D images is a challenging mathematical/computational task. For this reason, we focus on the use of families of mathematical functions best adapted to each specific problem. This approach allows structures to be determined faster, with more accuracy from a smaller amount of data.

Many viruses are knwon to have symmetric capsids to carry and protect their genetic material. Therefore, the presence of symmetry can be exploited allowing effective information extraction through the use of SAFs.