Overview

The group develops algorithms and statistical methods for computational genomics. In particular, we work on methods to analyze high-throughput sequencing data to study genetic diversity, epigenetics, and cancer. On the one hand, we develop the required theoretical foundations in algorithmic statistics, combinatorial optimization, and sequence algorithms and, on the other hand, we apply the resulting methods in collaboration with biomedical researchers to gain biological insights. Topics addressed in the group range from algorithms for low level data processing to questions of population genetics.

29 June 2014: The Genome of the Netherlands Consortium has published its first main findings in Nature Genetics (doi: 10.1038/ng.3021). Tobias Marschall is part of the consortium and contributed to discovery and genotyping of structural variations.

1 April 2014: The Algorithms for Computational Genomics group is established.

Research

Information on current research projects can be found on the Research page.