A similar application for an off-label expansion of the capsaicin 8% patch (Qutenza), to treat pain related to peripheral neuropathy in patients with HIV however was denied by the FDA because, according to panel member Edward C. Covington, MD, “I think we really need to know that something is helpful for folks who are desperate before we[FDA] approve it.”

Currently the 8% capsaicin patch is under review in Europe, with the code name NGX-4010, in partnership with Astellas Pharma Inc., for use by patients to lessen their pain of diabetic peripheral neuropathy.

Capsaicin as a topical lotion is also used in non-prescription circumstances for temporary relief of muscle or joint pain caused by strains, sprains, arthritis, bruising, backaches, as well as treating nerve pain (neuralgia) in people who have had herpes zoster, or “shingles.”

Another paper studied how capsaicin works its magic. Researchers in that case determined the compound overstimulated the pain-sensing neurons so much that the neurons finally became immune to receiving pain signals.

The treatment for neuralgia (pain from damaged nerves), neuropathy, and muscle and joint pain was elegantly explained due to the heat-stimulating function of capsaicin on nerve receptors.

Dr Mercola also weighed in on the capsaicin’s pain-relieving properties in neuropathy. He added that it has been used for:

Reducing or eliminate burning, stinging, itching, and redness of skin due to moderate to severe psoriasis

Weight loss due to its antioxidant and anti-inflammatory properties

Cancer treatment in breast, pancreatic, and bladder cancers

A final note is that capaicin is the active ingredient in the notorious “pepper spray” used by law authorities to subdue people due to its lachrymatory power.