I think that Codemaster's support can help you more than we, you should try to post on their forum aswell, if you haven't done that already.
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WimpeyOct 29 '11 at 11:19

Thanks for the comment. I've made this question to answer it myself with information I've gathered from the several fora out there. On Mac OS Leopard, I ended up using Crossover Games. I'll probably buy a licence for that; they contribute a lot back to the wine-project as well.
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Chris WesselingOct 29 '11 at 11:46

I have followed your instruction and I am able to use pylotro with your wrapper, but I still get the "Hardware texture compression support was not detected." error. Did I miss something? Is there anything you can help me to fix this issue. I will also check the codeweaver forum to see if I can find anything there.
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user16362Dec 12 '11 at 23:08

Very hard to say from what you tell. Is there any difference in the wine output when you run the game with the wrapper instead of wine?
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Chris WesselingDec 21 '11 at 18:09