Named for St. Vincent de Paul, founder of the Daughters of Charity in France in 1633, the hospital opened December 20, 1898 in the temporarily rented Henry F. DeBardelaben mansion at 206 15th Street South. Father Patrick A. O'Reilly founded the hospital together with Sisters Antonia, Benedicta, Patricia and Placida. Filling Birmingham's desperate need for a hospital, the magnificent original building was dedicated on this site on November 29, 1900 at a cost of $223,000. The State's first School of Nursing was founded here by Sister Chrysostom Moynahan, Alabama's first Registered Nurse. The current facility was dedicated May 25, 1974. On December 5, 1997 the Women's and Children's Center and Bruno Conference Center were added.

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