Steroid absorption enterohepatic recycling

Although I am usually not inclined to posit speculations on why a particular drug does or doesn't do something, in this case I will. Im guessing that the higher doses of Anadrol cause enough appetite suppression (at least anecdotally) to make eating rather difficult. It can also increase insulin resistance and glucose intolerance (5). This has the effect of making macronutrient absorption more inefficient, and could also be a factor in reducing gains when the dosage goes over 100mgs/day. Unfortunately, Anadrol also has a reasonably profound effect on your body's natural hormonal system, on par with most other oral steroids , but not as bad as most injectables, and its certainly not as harsh on your lipid profile as many anabolics are

Anabolic
steroids are synthetic substances related to male sex hormones
(androgens). Although it is illegal in the United States to possess or
distribute anabolic steroids for nonmedical use, a "black
market" for them exists, and many amateur and professional athletes
take them to enhance performance. In many cases, the athletes take doses
that are extremely high—perhaps 100 times the doses that might be
prescribed for medical use. As a result, they put themselves in real
danger of short-term and long-term health problems. Blood testing, as has
been used in the Olympic Games, can detect, identify, and quantify the
presence of anabolic steroids in the blood of athletes, which can lead to
the disqualification of an athlete.