NINDS and the National Cancer Institute (NCI) encourage grant applications for research on understanding and preventing brain
tumor dispersal. This announcement is supported by 2 funding mechanisms: R01 and R21.

Many brain tumors are highly invasive and, therefore, extremely difficult to treat. Cells from the primary tumor often invade
surrounding brain tissues, so that removal of the main tumor mass is not enough to prevent recurrence. The goal of this announcement
is to promote studies that: (1) identify the properties of brain tumor cells that cause them to migrate; (2) determine how
interaction of tumor cells with normal brain elements affects migration; and (3) translate understanding of these parameters
into interventions that target invading tumor cells.