The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen.

Number of paths to term:

27

denotes an 'is-a' relationshipdenotes a 'part-of' relationshipdenotes a 'regulates' relationshipdenotes a 'positively-regulates' relationshipdenotes a 'negatively-regulates' relationship