PMS2 and POLR2J gene families as molecular markers of the higher primates evolution

PMS2 and POLR2J gene families as molecular markers of the higher primates evolution
Shematorova, E.; Shpakovski, D.; Shpakovski, G.
2010-09-30 00:00:00
We have studied the molecular evolution of two gene families specific for primates: POLR2J of the transcription system and PMS2 of the mismatch repair (MMR) system. The appearance of these families and upgrading of their genetic structures was shown to neatly correlate with the main stages of the biological evolution of higher primates. Our results indicate that the PMS2 and POLR2J genes can serve as helpful and reliable molecular markers of anthropogenesis.
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PMS2 and POLR2J gene families as molecular markers of the higher primates evolution

Abstract

We have studied the molecular evolution of two gene families specific for primates: POLR2J of the transcription system and PMS2 of the mismatch repair (MMR) system. The appearance of these families and upgrading of their genetic structures was shown to neatly correlate with the main stages of the biological evolution of higher primates. Our results indicate that the PMS2 and POLR2J genes can serve as helpful and reliable molecular markers of anthropogenesis.