Previous HGNC Symbols for CLEC10A Gene

Previous GeneCards Identifiers for CLEC10A Gene

Summaries for CLEC10A Gene

Entrez Gene Summary for CLEC10A Gene

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for CLEC10A Gene

CLEC10A (C-Type Lectin Domain Family 10, Member A) is a Protein Coding gene.
GO annotations related to this gene include carbohydrate binding.
An important paralog of this gene is CLEC4D.

UniProtKB/Swiss-Prot for CLEC10A Gene

Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.

Graphical View of Domain Structure for InterPro Entry

UniProtKB/Swiss-Prot:

Function for CLEC10A Gene

Molecular function for CLEC10A Gene

UniProtKB/Swiss-Prot Function: Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.