CRYING and Klonopin

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CRYING Symptoms and Causes

Going home with a new baby is exciting, but it can be scary, too. Newborns have many needs, like frequent feedings and diaper changes. Babies can have health issues that are different from older children and adults, like diaper rash and cradle cap.

Your baby will go through many changes during the first year of life. You may feel uneasy at first. Ask your health care provider for help if you need it.

CRYING Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.

Days/week mothers report reading with their infants; Reading with their baby is one of mother's favorite shared activities; Knowledge of the typical peak of infant CRYING; Having heard what can happen if a baby is shaken; Reading together is one of the baby's 3 favorite activities.; Number of children's books in the home; Reading with their baby is identified as a way of preparing him/her for school; Talking, singing and/or playing with their babies is identified as a favorite shared activity; Number of calming strategies for parenting stress identified; Number of soothing strategies to calm fussy babies identified; Knowledge that responding to babies younger than 6 months of age whenever they cry won't spoil them; Knowledge that shaking a baby can cause brain damage or death

The treatment success (defined as the percentage of children achieving a reduction in the daily average CRYING time 50% during the study); Change in the duration of CRYING (minutes per day).; A reduction in the daily average CRYING time, to <3 h/d.; Change in Infant sleep duration in (minutes/day); Change in Maternal mental health scores.

Changes to the duration of CRYING per day; Proportion of infants achieving clinically-relevant reduction in CRYING time; Proportion of infants reported with absence of 'colic'; Number of adverse events; Changes to parental anxiety and depression scores; Parental Global Impressions of Change in symptoms; Cost of NHS resources used; Change to Severity of colic-related specific symptoms; Change to Parental Global Impressions of Severity; Effectiveness of Blinding

The responder rate (infants for whom daily CRYING time decreases by 50% compared to baseline, D0) at D7 in the probiotic group compared to placebo. The daily CRYING time will be sound recorded during 24 hours at D0 and D7.and expressed in minutes.; The responders rates at D14 and D21 in the probiotic group compared to the placebo group.

Difference in pain scores related to venipuncture in the study population as assessed by the Face, Legs, Activity, Cry and Consolability Pain Scale before the administration of sucrose and one minute after the venipuncture; The difference in pain scores using the Neonatal Infant Pain Scale (NIPS).

Change in maternal mood and prevalence/severity of postpartum depression.; The effect of behavioral intervention for infants on infant development; The effect of behavioral intervention on infant sleep and fuss behavior

To evaluate the intestinal microflora of colicky infants before and after the Lactobacillus reuteri or placebo administration (coliforms, Clostridium butyricum, Lactobacilli, Bifidobacteria) with FISH technique.; Reduction of the daily average CRYING time from baseline to the end of the treatment period, to less than 3 hours a day, the cut-off proposed by Wessel and number of responders versus non-responders in each group at the end of the treatment

* Reduction of daily average CRYING time to less than 3 hours from baseline to the end of the study period as measured using a daily reporting of CRYING time by the parents.; Number of responders versus non-responders with L. reuteri versus placebo at end of the study.

If you think you may have a medical emergency, call your doctor or 911 immediately.

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