AbstractExperimental results to determine the friction coefficient and wear characteristics of elements of the friction pair in the presence of lithium based lubricants, including mixtures of liquid crystalline compounds – copper carboxylates are presented. It was established that introduction of liquid crystal mixtures of copper carboxylates into lithium greases reduces the friction coefficient in 2,67 times and wear of friction pair elements in 1,28–2,35 times. This is explained by the synergistic effect of a mixture additive with defined composition due to structuring of the basic grease and the further improvement of its sorption in the boundary layer. Using of these additives allows, in the long term, to increase resource of elements of tribological pairings, and to reduce the cost of power for the drive mechanisms of machines.