Description:

Several platelet response studies have demonstrated a significant variability in the dose-response to regular doses of clopidogrel in patients undergoing percutaneous coronary intervention (PCI). Further, some studies have also suggested that a higher loading dose (LD) of clopidogrel (600 mg) may help overcome some of this resistance. There are, however, limited data with regard to the use of a higher maintenance dose (MD) for overcoming clopidogrel resistance. The VASP-02 trial sought to invest...

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