If you're able to hit someone in the center of the chest with one of those rounds I am sure he will die. (You will probably not have hearing after the situation has ended and you have to buy a hearing aid for permanent ear damage.)

Should rate about a 350 on this scale. I would guess that means you could 1 shot stop about 7 bad guys if they stood in a column! That round can penetrate an elephant's skull. And the muzzle flash would bar-b-q it.