Edward J. Kelsey's interests include the application of relativistic quantum electrodynamics to simple atomic systems, electron-atom scattering, as well as, more recently, software design and software quality assurance. His 1978 paper (with L. Spruch), "Retardation effects on high Rydberg state: A retarded R-5 polarization potential," is included in the compendium of 1,000 seminal papers of the Physical Review's first 100 years (H.H. Stroke, The Physical Review, The First Hundred Years, A Selection of Seminal Papers and Commentaries, AIP Press, New York, 1995, p. 101). His papers have been published in recognized journals such as Physical Review A and the Journal of Mathematical Physics.