The researchers found that MPO was elevated in prepubertal obese children. MPO was associated with proinflammatory and cardiovascular risk biomarkers, including CRP, MMP-9, and resistin. The best predictor of MPO was insulin resistance, calculated by the homeostatic assessment model.

"The main findings of this study were that plasma MPO was elevated in prepubertal obese children and that this enzyme was associated with proinflammatory and cardiovascular risk factors," the authors write.