pvs2 - 1/28,1/31 Ch2 Inflammation Cytokines chemicals cells...

1/28,1/31Ch2 Inflammation•Cytokines – chemicals cells use to communicate between cells (like pheromones)•Blood Smear/SampleoSent of for chemical screeningoHemogram/CBC (Complete Blood Count)Blood cell breakdown in a sample of bloodGiemsa stain (blue stain) or Right Giemsa stain will consist of some blue and red coloringDispersion of white cellsoSmear prevents shrinking opposed to preparations•Slide 23: Blood Cells originate in Bone Marrow with a megakaryoctye (large cell at center)oPluripotential – possibility of becoming any cell typeCan’t see nucleus50/50 breakdown in bone marrow 50% become erythrocytes 50% become WBCoMegakaryocyteDoesn’t circulateBreakup to become platelets/thrombocytes•Slied 24: Types of Blood CellsoErythrocytesRed Blood CellUsed as a measure because 7μm in diameterRound/oval shapeZone of power at centerDoughnut shaped or biconcaveoPlatelets/thrombocytesDon’t have nucleiFirst line of defense in break of blood vessel•Platelets stick to breakage then erythrocytes stick to themoWhite Blood CellsPolymorphs:•Collectively Neutrophils, Eosinophils & BasophilsGranulocytes•WBC with lots of granules•Neutrophils, Eosinophils & BasophilsNeutrophils/Polymorphonuclear leukocytes•First line of defense•Phagocytes: microphages•Granules in cytoplasm•Neutral in color

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