Adherence to Ophthalmologic Monitoring for Antimalarial Toxicity in a Lupus Cohort

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Bernatsky S, Pineau C, Joseph L, Clarke A. Adherence to ophthalmologic monitoring for antimalarial toxicity in a lupus cohort. J Rheumatol 2003;30:1756–60. In the PubMed citation and in the online Abstract of this article, under Results, the comparison math symbols are incorrect. The Results section of the Abstract should read: “Of 195 subjects with at least one full year of antimalarial exposure during 1996–2001, 5 refused participation and data on ophthalmology monitoring was incomplete for 42. Of the remaining 148 patients, 47 (32%) had missed at least one annual ophthalmology assessment (were nonadherent) during the interval; almost half of these had missed ≥ 2 assessments. Nonadherence was present in 50% of the 52 patients who had been taking an antimalarial agent for ≥ 5 years. In adjusted logistic regression models, cumulative damage (measured by the Systemic Lupus International Collaborating Clinics/ACR Damage Index) and antimalarial exposure ≥ 5 years were predictive of nonadherence. Adjusted estimates indicated a 1.2-fold increase (95% CI 1.0, 1.5) in the odds of nonadherence for every point increase in the total Damage Index score. The adjusted OR for individuals exposed to an antimalarial for ≥ 5 years was 5.2 (95% CI 2.1, 13.8).”

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