The results support a comparatively high adjusted relative risk of liver injury among patients exposed concurrently to multiple antimicrobials and modest elevations in the risk for several antimicrobials used alone; however, we found little evidence of any strong effect of commonly used antimicrobials on the risk of liver injury.

We reveal that specific histone modifications are associated with arsenic exposure and oxidative damage, and persistent dysregulation of these histone modifications could be a potential biomarker that evaluates the burden of arsenic exposure and predicts the adverse biological effects.

Altogether, our results evidenced that people living in arsenic-contaminated areas are at risk and that AS3MT genetic variation may play an important role modulating such risk in northern Mexico, especially among children.

This report describes 28 additional cases of hydrogen cyanamide-related illness that occurred during 2002-2004 in Italy; these illnesses suggest that the preventive measures adopted in 2003 to protect agricultural workers are inadequate.

We report urinary biomarkers for occupational exposure to N,N-dimethylformamide and reveal dose-response relationships between their levels and liver injury, with males having a greater risk of injury.

Our results demonstrate that chronic and heavy alcohol use in pregnancy impairs folate transport to the fetus. Altered folate concentrations within the placenta and in the fetus may in part contribute to the deficits observed in the fetal alcohol spectrum disorders.

We report a method for the determination of glyphosate in heart blood of a corpse by ion chromatography; this method is simple, sensitive, accurate, and can rapidly provided reliable clues and evidences for glyphosate poisoning cases.

We observed a deleterious association between current and cumulative lead burden and risk of psychiatric symptoms. At a given cumulative lead burden, participants with the ALAD 1-1 genotype appeared to be at greater risk than participants who were carriers of at least one variant ALAD allele.

Our investigations revealed a mass lead intoxication that occurred through inhalation and ingestion of soil and dust heavily contaminated with lead as a result of informal and unsafe used lead-acid batteries recycling.

The high levels of environmental contamination, percentage of children < 5 years of age with elevated blood lead levels (97%, > 45 micrograms per deciliter), and incidence of convulsions among children before death (82%) suggest that most of the recent childhood deaths in the two surveyed villages were caused by acute lead poisoning from gold ore-processing activities.

This study sought to characterize acute poisoning with regard to demographic factors (i.e. age, sex and residence), common toxic agents used and their case fatality rates as well as the overall mortality rate of acute poisoning.