Fusion

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Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GRMZM2G357595_P01

Grancalcin (296 aa)

Predicted Functional Partners:

DEK1

Defective kernel1 ; Essential protein involved in epiderm development. Required for aleurone cell development in the endosperm probably by maintaining and restricting the aleurone and embryonic epidermal L1 cell-layer fates as well as meristems organization. Involved in the maintenance of adaxial/abaxial axis information in developing leaves, probably by regulating cell proliferation and expansion. Does not need calcium ions to be active (2159 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

DEK1

GRMZM2G082529_P01

GRMZM2G321753_P01

GRMZM2G082529_P01

Defective kernel1 ; Essential protein involved in epiderm development. Required for aleurone cell development in the endosperm probably by maintaining and restricting the aleurone and embryonic epidermal L1 cell-layer fates as well as meristems organization. Involved in the maintenance of adaxial/abaxial axis information in developing leaves, probably by regulating cell proliferation and expansion. Does not need calcium ions to be active

Hypothetical protein LOC100383198

0.539

DEK1

GRMZM2G357595_P01

GRMZM2G321753_P01

GRMZM2G357595_P01

Defective kernel1 ; Essential protein involved in epiderm development. Required for aleurone cell development in the endosperm probably by maintaining and restricting the aleurone and embryonic epidermal L1 cell-layer fates as well as meristems organization. Involved in the maintenance of adaxial/abaxial axis information in developing leaves, probably by regulating cell proliferation and expansion. Does not need calcium ions to be active

Grancalcin

0.949

DEK1

Zm.133492

GRMZM2G321753_P01

GRMZM2G139773_P01

Defective kernel1 ; Essential protein involved in epiderm development. Required for aleurone cell development in the endosperm probably by maintaining and restricting the aleurone and embryonic epidermal L1 cell-layer fates as well as meristems organization. Involved in the maintenance of adaxial/abaxial axis information in developing leaves, probably by regulating cell proliferation and expansion. Does not need calcium ions to be active

Vacuolar protein-sorting protein bro1

0.539

DEK1

Zm.97520

GRMZM2G321753_P01

GRMZM2G168855_P01

Defective kernel1 ; Essential protein involved in epiderm development. Required for aleurone cell development in the endosperm probably by maintaining and restricting the aleurone and embryonic epidermal L1 cell-layer fates as well as meristems organization. Involved in the maintenance of adaxial/abaxial axis information in developing leaves, probably by regulating cell proliferation and expansion. Does not need calcium ions to be active

ALG2-interacting protein X

0.539

GRMZM2G082529_P01

DEK1

GRMZM2G082529_P01

GRMZM2G321753_P01

Hypothetical protein LOC100383198

Defective kernel1 ; Essential protein involved in epiderm development. Required for aleurone cell development in the endosperm probably by maintaining and restricting the aleurone and embryonic epidermal L1 cell-layer fates as well as meristems organization. Involved in the maintenance of adaxial/abaxial axis information in developing leaves, probably by regulating cell proliferation and expansion. Does not need calcium ions to be active

0.539

GRMZM2G082529_P01

GRMZM2G324643_P01

GRMZM2G082529_P01

GRMZM2G324643_P01

Hypothetical protein LOC100383198

Hypothetical protein LOC100272455

0.460

GRMZM2G082529_P01

GRMZM2G357595_P01

GRMZM2G082529_P01

GRMZM2G357595_P01

Hypothetical protein LOC100383198

Grancalcin

0.865

GRMZM2G082529_P01

Zm.133492

GRMZM2G082529_P01

GRMZM2G139773_P01

Hypothetical protein LOC100383198

Vacuolar protein-sorting protein bro1

0.800

GRMZM2G082529_P01

Zm.20359

GRMZM2G082529_P01

GRMZM2G033846_P01

Hypothetical protein LOC100383198

Caltractin

0.460

GRMZM2G082529_P01

Zm.97520

GRMZM2G082529_P01

GRMZM2G168855_P01

Hypothetical protein LOC100383198

ALG2-interacting protein X

0.800

GRMZM2G082529_P01

umc2698

GRMZM2G082529_P01

GRMZM2G391364_P01

Hypothetical protein LOC100383198

LOC100282202

0.460

GRMZM2G324643_P01

GRMZM2G082529_P01

GRMZM2G324643_P01

GRMZM2G082529_P01

Hypothetical protein LOC100272455

Hypothetical protein LOC100383198

0.460

GRMZM2G324643_P01

GRMZM2G357595_P01

GRMZM2G324643_P01

GRMZM2G357595_P01

Hypothetical protein LOC100272455

Grancalcin

0.563

GRMZM2G324643_P01

Zm.133492

GRMZM2G324643_P01

GRMZM2G139773_P01

Hypothetical protein LOC100272455

Vacuolar protein-sorting protein bro1

0.460

GRMZM2G324643_P01

Zm.97520

GRMZM2G324643_P01

GRMZM2G168855_P01

Hypothetical protein LOC100272455

ALG2-interacting protein X

0.460

GRMZM2G357595_P01

DEK1

GRMZM2G357595_P01

GRMZM2G321753_P01

Grancalcin

Defective kernel1 ; Essential protein involved in epiderm development. Required for aleurone cell development in the endosperm probably by maintaining and restricting the aleurone and embryonic epidermal L1 cell-layer fates as well as meristems organization. Involved in the maintenance of adaxial/abaxial axis information in developing leaves, probably by regulating cell proliferation and expansion. Does not need calcium ions to be active

0.949

GRMZM2G357595_P01

GRMZM2G082529_P01

GRMZM2G357595_P01

GRMZM2G082529_P01

Grancalcin

Hypothetical protein LOC100383198

0.865

GRMZM2G357595_P01

GRMZM2G324643_P01

GRMZM2G357595_P01

GRMZM2G324643_P01

Grancalcin

Hypothetical protein LOC100272455

0.563

GRMZM2G357595_P01

Zm.133492

GRMZM2G357595_P01

GRMZM2G139773_P01

Grancalcin

Vacuolar protein-sorting protein bro1

0.865

GRMZM2G357595_P01

Zm.20359

GRMZM2G357595_P01

GRMZM2G033846_P01

Grancalcin

Caltractin

0.694

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Network Stats

Network Stats analysis is still ongoing, please wait ...

Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: