Dengue fever is an infectious disease carried by mosquitoes and caused by any of four relateddengue viruses. This disease used to be called “break-bone fever” because it sometimes causes severe joint and muscle pain that feels like bones are breaking.

There are three types of dengue fever in order of less severe to most: the typical uncomplicated dengue fever, dengue hemorrhagic fever (DHS) and dengue shock syndrome (DSS).

The World Health Organization (WHO) estimates there may be 50–100 million dengue infections worldwide every year. However, new research from the University of Oxford and the Wellcome Trust, using cartographic approaches, estimate there to be 390 million dengue infections per year worldwide.