During the past few decades, opportunistic fungal pathogens have become increasingly recognized as a cause of infection in severely ill or immunocompromised patients [1,2]. Although Aspergillus species remains the most common mold to cause invasive infection, other pathogens, such as Scedosporium, are becoming more common [1-3]. Two members of this genus, Scedosporium apiospermum and Scedosporium prolificans, are considered major human pathogens [4].

Invasive fungal infection has been defined in accordance with certain criteria proposed by the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group (EORTC) and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (NIAID/MSG) [1]. Proven mold infection is defined as:

●Histopathologic examination revealing tissue invasion and a culture result positive for mold.

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