Wealthiest areas have an almost 30% increased risk of hip fracture compared to the most deprived. Differences in age-sex composition and a higher prevalence of obesity in deprived areas could explain this higher risk.

Altogether, these results further suggest that, in addition to osteocalcin, other bone-derived signals affect white adipose tissue and energy expenditure contributing to the regulation of energy metabolism.

Short-term after spinal cord injury there is a marked increase in bone turnover and bone loss, the latter associated with an increase in Dkk-1 serum levels. The persistence of increased levels of this Wnt antagonist throughout the study and their relationship with the magnitude of bone loss suggests a contributory role of this mediator in […]

Bone. 2015 Jan;70C:2-9. doi: 10.1016/j.bone.2014.08.011. Current interest in stem cells in bone as in other fields is intertwined with that shift. New opportunities and also new challenges arise. This article is part of a Special Issue entitled “Stem cells and bone”. Autor: Bianco P.