In order to set up MySQL you will need to install it first. If you have not, I recommend using Aaron Faby's fantastic installer (http://www.serverlogistics.com). After installing MySQL you will need the correct JDBC driver, which can be downloaded from the MySQL website. (put it into /Library/Java/Extensions/)

From there, you will need to do the following, using the "Model:Switch Adaptor..." menu item:

Use the JDBC connector

Username: <my_database username>

Password: <my_database password>

URL: jdbc:mysql://localhost/<my_database>

Driver (optional): com.mysql.jdbc.Driver (Note: in old MySQL versions it was org.gjt.mm.mysql.Driver)

You will need the JDBC driver for SQL 2000 from Microsoft. A search for Microsoft SQL Server 2000 JDBC should give you the right link. You can untar the file and place the resulting .jar files in /Library/Java/Extensions.