Ultra-high Resolution Three Dimensional Imaging in Live Cell and Tissue Samples

We are in an exciting era of biomedical engineering and biology where the inner workings of cells can be explored by rapidly developing imaging methods. The recent advent of super-resolution microscopy breaks Abbe’s century-old resolution limit allowing, for the first time, biological observation of the extreme details in a cell and is recently recognized by the Nobel Prize in 2014.

The Huang laboratory focuses on developing the next generation of super-resolution microscopy methods that are capable of revealing dynamics of subcellular structures and large protein assemblies - previously impossible to visualize using conventional super-resolution microscopy, with nanometer resolution in live cell. Using our innovative methods, we aim to understand the functional mechanisms of cellular processes such as cell division.

With a highly interdisciplinary approach, we build novel super-resolution instruments that synergistically combines ideas from engineering and physics such as single photon interference, nanofabrication and adaptive optics. At the same time, we seek to invent new analysis methods that take advantages of concepts in mathematics, statistics and signal processing, such as sparsity, Bayesian inference, parallelized computing and machine learning. Through extensive collaboration with biologists, we will apply these techniques to tackle fundamental biological questions that were previously inaccessible.​Yes, we are recruiting! Whether you are an experimentalist, a theoretician or (anything in between) and want to work on leading projects in biomedical imaging field, building novel imaging instruments, developing novel algorithms and addressing the fundamental molecular and biomedical questions, send us an email!

We are intrinsically a cross-disciplinary and collaborative lab. We work extensively both within the institute (e.g. with Biological Sciences, Electrical and Computer Engineering, Mechanical Engineering, etc.) and outside. Our students will have the opportunities to travel both domestically and internationally to get trained from other top experts in the related field to expedite their professional development and research. We strongly encourage and support our trainees to actively attend multiple national conferences each year.

We are a newly founded lab and are now looking for talented and motivated graduate students and postdoc researchers. Interested? Send us an email for more questions or skype with Fang to talk about potential projects for you!