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8 Answers
8

RootkitRevealer is an advanced rootkit
detection utility. It runs on Windows
NT 4 and higher and its output lists
Registry and file system API
discrepancies that may indicate the
presence of a user-mode or kernel-mode
rootkit. RootkitRevealer successfully
detects many persistent rootkits
including AFX, Vanquish and
HackerDefender (note: RootkitRevealer
is not intended to detect rootkits
like Fu that don't attempt to hide
their files or registry keys).

"ThreatExpert is an advanced automated threat analysis system designed to analyze and report the behavior of computer viruses, worms, trojans, adware, spyware, and other security-related risks in a fully automated mode."
-- www.threatexpert.com/default.aspx