Additional Products That React With Clomipramine

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Taking clomipramine with linezolid can increase your chance of developing dangerous side effects, including serotonin syndrome. Do not take these medications together.

Methylphenidate

Methylphenidate can increase the level of clomipramine in your blood, increasing your risk of side effects. Your healthcare provider may need to decrease your clomipramine dose.

Monoamine Oxidase Inhibitors (MAOIs)

Taking clomipramine with MAOIs can increase your chance of developing dangerous side effects. Do not take clomipramine if you have taken an MAOI within the past two weeks.

Phenothiazines

Taking clomipramine with phenothiazine medications can increase the level of clomipramine in your blood, increasing your risk of side effects. Also, combining clomipramine with certain phenothiazines can increase your risk of a dangerous irregular heart rhythm called QT prolongation. Talk to your healthcare provider before taking these medications together.

Phenytoin (Dilantin)

Phenytoin can decrease the level of clomipramine in your blood, perhaps making it less effective. Your healthcare provider may need to increase your clomipramine dose.

Pressors

Taking clomipramine with pressor medications can increase your risk of side effects. Your healthcare provider may need to adjust your dose of these medications.

SSRIs or SNRIs

Taking clomipramine with SSRIs or SNRIs can increase the level of clomipramine in your blood, increasing your chance of side effects and increasing the risk for serotonin syndrome. Your healthcare provider may need to adjust your dose of these medications or use caution when switching from one medicine to another.

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