I notice a slight difference in his reaction and standing tackles, other than that not much. But like others said he will 100% get upgraded. Only issue is, if you have a hybrid you need to include Kolarov or Immobile in your squad to get him on 10 chem.

I'm playing a Serie A team atm with Immobile up top so chem not an issue atm, thanks guys, I'll do it, as you say he'll get upgraded and I think Lazio could do ok in EL so fingers crossed for a few more upgrades