Giant cell granuloma is a relatively rare benign entity but can be locally aggressive. Histologically characterized by
intense proliferation of multinucleated giant cells and fibroblasts. Affects bone supported tissues. Definitive diagnosis
is given by biopsy. Clinically manifest as a mass or nodule of reddish color and fleshy, occasionally ulcerated
surface. They can range from asymptomatic to destructive lesions that grow quickly. It is a lesion to be considered
in the differential diagnosis of osteolytic lesions affecting the maxilla or jaw. Its management passed from conservative
treatment with intralesional infiltration of corticosteroids, calcitonin or interferon, to the surgical resection
and reconstruction, for example with microvascular free flaps.
Keywords: giant cell granuloma, intralesional injection, microvascular free flap, fibula....
[Llegir més ...]

[-]

Giant cell granuloma is a relatively rare benign entity but can be locally aggressive. Histologically characterized by
intense proliferation of multinucleated giant cells and fibroblasts. Affects bone supported tissues. Definitive diagnosis
is given by biopsy. Clinically manifest as a mass or nodule of reddish color and fleshy, occasionally ulcerated
surface. They can range from asymptomatic to destructive lesions that grow quickly. It is a lesion to be considered
in the differential diagnosis of osteolytic lesions affecting the maxilla or jaw. Its management passed from conservative
treatment with intralesional infiltration of corticosteroids, calcitonin or interferon, to the surgical resection
and reconstruction, for example with microvascular free flaps.
Keywords: giant cell granuloma, intralesional injection, microvascular free flap, fibula.