Disable IE Home Page

For SpywareBlaster, under Tools / Misc. IE Settings / Checking the Disable IE Home Page box works. The next time I open a browser window the area is greyed out, UNTIL the next morning when I open a browser to check Windows update. Then the homepage is no longer greyed out, it is hijacked to msn. I don't use MSN or MSN messenger but do have Windows Messenger that came with my new computer, a modest HP Celeron.