Written by Merel Dagher (PEACE Advisor)

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The correct answer is e. Rapid stress response involves nerve impulses that directly target the spinal cord. From there, the spinal cord sends more nerve impulses to the medulla of the adrenal gland, triggering the production of epinephrine from tyrosine. This means there is in fact a hormonal response. Both systems produce some hormonal change, so this is not different between the two. In slow stress response, CRF binds to the anterior pituitary, triggering the secretion of ACTH, which then binds to the cortex of the adrenal gland and causes the conversion of cholesterol to cortisol. High levels of cortisol can then feedback on the anterior pituitary, preventing the production of ACTH.