Abstract : The design of flexible lifting bodies in the naval industry, such as propelleror rudders, create some new design problems. This thesis proposes a numerical method validated by experimental comparison for solving the case of lifting bodies loaded by flow with or whitout cavitation. The tests are carried out in the hydrodynamic tunnel of the French Naval Academy Research Institute, on a polyacetate flexible hydrofoil NACA66-312 (mod.). During tests, strains and vibrations are measured for comparisons with numerical results. The numerical method uses a sequential synchrone iterative partitionned coupling betweena structural finite-element code (ANSYS Mechanical) and a finite-volume code (ANSYS CFX). Good agreement between numerical and experimental results for displacements, and stresses of the structure is highlighted. For the cavitating flow, a good agreement for the cavitation dynamic is observed and the stresses are evaluated with satisfying accuracy.