Alpha Linolenic Acid (ALA)

Flax seed contains high levels of ALA. Are there any side effects or negative
health risks to using flax seed as a result that?

Flax seed, and flax seed oil contain high levels of alpha linolenic acid (ALA)
whose side effects are often debated to be cancerous. There is information
for and against the cancer risk of the effects alpha linolenic acid (ALA)
in flax seed oil. Clinical trials argue both for and against increased breast
cancer risk as a side effect of higher ALA levels. Animal and test tube studies
suggest a possible protective role of alpha linolenic acid - a positive side
effect - against breast cancer. On the other side of the argument, another
animal study and a preliminary human study showed negative effects to high
levels of dietary ALA, suggesting increased risk of breast cancer. Another
preliminary human study reported that high levels of alpha linolenic acid
in breast tissue are associated with less advanced breast cancer at the time
of diagnosis. In test tube studes ALA was found to promote cancer cell growth
as a health risk, but that preliminary human studies have shown alpha linolenic
acid to be associated with either an increased or decreased risk, or no change
at all. More data that indicates arbitary side effects.

However, flax seed oil advocates speculate that the apparent association between
ALA and cancer may not be linked to flax seed byproducts but rather the prevalent
use of meat, implying a false link to health risks and flax seed oil uses.
In some studies, however, the saturated fat, which rules our meat products,
were taken into consideration, and alpha linolenic acid still correlated with
increased health risks, and cancerous side effects. The associations between
ALA and cancer might eventually be shown to be caused by substances found
in foods rich in ALA rather than by ALA itself. The effect of ALA as an isolated
substance, and of flax seed oil on the risk of cancer in humans remains unclear.
Studies involving test tube studies and animal testing suggest protective
health effects. Yet, some preliminary human trials indicate a cause for concern.
It is still to early to suggest that ALA and flax seed oil will either provide
positive or negative side effects as they relate to human cancer at this time.

flax seed oil is not suitable for cooking and should be stored in an opaque,
airtight container in the refrigerator or freezer. If the oil has a noticeable
odor it is probably rancid and should be discarded. As with any source of
fiber, flax seed should not be taken if there is possibility that the intestines
are obstructed. People with scleroderma (systemic sclerosis) should consult
a doctor before using flax seed. Although a gradual introduction of fiber in
the diet may improve bowel symptoms in some cases, there have been several
reports of people with scleroderma developing severe constipation and even
bowel obstruction requiring hospitalization after fiber supplementation.35
Animal research suggests that large amounts of flax seed or lignans consumed
during pregnancy might adversely affect the development of the reproductive
system. No studies have attempted to investigate whether this could be a problem
in humans. Allergic reactions to flax seed have occasionally been reported,
but are considered very uncommon. At the time of writing, there were no well-known
drug interactions with flax seed oil.