Edmonton, Alberta A new test developed by Edmonton-based Innovotech™ Inc. will now allow doctors to more accurately identify the right antibiotics required to treat serious, chronic infections that are biofilm based. With more than 80 per cent of infections in the developed world caused by...

BOSTON Nearly 20 years ago, it was discovered that bacteria known as Helicobacter pylori were responsible for stomach ulcers. Since then, antibiotics have become the primary therapy used to combat the H. pylori infection, which affects approximately six percent of the world population and is ...

Researchers at the University of Leeds have developed chemicals which kill the most deadly malaria-causing parasite, Plasmodium falciparum including those resistant to existing drugs.
The compounds work by preventing the enzyme dihydroorotate dehydrogenase (DHODH) - essential to the growth o...

Sven Enerbck, Professor at the Institute of Biomedicine at the Sahlgrenska Academy, University of Gothenburg, Sweden, is one of the scientists who published their results in The New England Journal of Medicine this week. Studies carried out by Enerbck and others show that adults use brown fat to...

A new therapy for metastatic prostate cancer has shown considerable promise in early clinical trials involving patients whose disease has become resistant to current drugs.
Chemists and biologists at UCLA and colleagues at several other institutions, including Memorial Sloan-Kettering Cancer...

Researchers at North Carolina State University are looking to soy as a way to make traditional canine cancer therapy more effective, less stressful for the dog and less costly for the owners.
Dr. Steven Suter, assistant professor of oncology, and NC State colleagues studied genistein - a molecu...

A new therapy for metastatic prostate cancer has shown considerable promise in early clinical trials involving patients whose disease has become resistant to current drugs.
Of 30 men who received low doses of one the drugs in a multisite phase I/II trial designed to evaluate safety, 22 showed a...

Scientists at the University of Liverpool have determined the atomic structure of the 'binding' between a brain protein and an antibody that could be key to treating patients with diseases such as variant CJD.
Variant Creutzfeldt-Jakob Disease (vCJD) is part of a family of rare progressive neur...

Abnormal heart rhythms arrhythmias are killers. They strike without warning, causing sudden cardiac death, which accounts for about 10 percent of all deaths in the United States.
Vanderbilt investigators have discovered a new molecular mechanism associated with arrhythmias. Their findings, repo...

Adelaide researchers have made a world breakthrough in treating premature babies at risk of developmental disorders.
A six-year study led by Dr Maria Makrides from the Women's and Children's Health Research Institute and Professor Bob Gibson from the University of Adelaide has demonstrated that...

Kidney cancer is typically without symptoms until it has spread to other organs, when it is also the most difficult to treat. Newer chemotherapies show great promise for extending survival during later disease stages, but they can also be highly toxic.
In one of the first discoveries of its ki...

PITTSBURGH--Research from the University of Pittsburgh could expand the options for controlling schizophrenia by identifying a brain region that responds to more than one type of antipsychotic drug. The findings illustrate for the first time that the orbitofrontal cortex could be a promising targe...

CLEMSON, SC Nursery and greenhouse operations depend on the use of fertilizers, growth regulators, insecticides, and fungicides. Growers also rely on the use of soilless media, or substrate, in the production of container crops. Concerns arise when excessive irrigation of the container crops grow...

Toronto, ON (September 22, 2008) Researchers at the University of Calgary have found a new method of fighting severe lung infections in people with cystic fibrosis (CF). These findings are published in Proceedings of the National Academy of Science USA, this week.
Communities of bacteria gr...

PHOENIX, Ariz. Sept. 1, 2008 Researchers at the Translational Genomics Research Institute (TGen) today announced a new approach to treating endometrial cancer patients that not only stops the growth of tumors, but kills the cancer cells.
In a potentially major breakthrough, TGen scientists an...

PHILADELPHIA A combination of chemotherapy agents that have been tested in other tumor types appears to be a promising alternative to standard treatment for advanced non-small cell lung cancer, according to a report in the August 15 issue of Clinical Cancer Research, a journal of the American A...

BIRMINGHAM, Ala. Proven combinations of medicines and the introduction of new anti-arthritis drugs have significantly improved the treatment of rheumatoid arthritis (RA), according to guidelines issued by the American College of Rheumatology and co-authored by physicians at the University of Alab...

Angiocidin, a tumor-inhibiting novel protein discovered by Temple University researchers, may also have a role as a new therapeutic application in treating leukemia, according to a study by the researchers.
The study, "The Novel Angiogenic Inhibitor, Angiocidin, Induces Differentiation of Mono...

A novel concept for the treatment of mitochondrial disorders using directed enzyme replacement therapy (DERT) has won for a Hebrew University of Jerusalem doctoral candidate one of this year's Kaye Innovation Awards. The awards were presented at this year's 71st meeting of the Hebrew University Bo...

New research on environmental influences on health and disease has begun to shed light on why genetically identical individuals demonstrate different characteristics, such as susceptibility to disease. Scientists have found that environmental exposure to nutritional, chemical and physical factors ...

A research team led by scientists at the University of Minnesota Medical School and Oregon Health & Science University have outlined the challenges and made suggestions on how to advance research and improve treatments for brain disorders.
The review article is published in the January 2008 issue...

Cambridge, MA, November 28, 2007 - Sirtris Pharmaceuticals, Inc. (NASDAQ: SIRT), a biopharmaceutical company focused on discovering and developing small molecule drugs to treat diseases of aging, announced today that findings in the journal Nature demonstrate that Sirtris has developed novel drug ...

Researchers have discovered the first microRNAs tiny bits of code that regulate gene activity linked to each of 10 major degenerative muscular disorders, opening doors to new treatments and a better biological understanding of these debilitating, poorly understood, often untreatable diseases. Th...

PITTSBURGH, Aug. 28 Gamma globulin, a type of antibody isolated from blood samples that used to be routinely given to health care workers and international travelers to protect them from infectious diseases, is a highly effective treatment for pinkeye with little apparent toxicity, according to a...

A unique nanoparticle made in a laboratory at the University of Central Florida is proving promising as a drug delivery device for treating glaucoma, an eye disease that can cause blindness and affects millions of people worldwide.
“The nanoparticle can safely get past the blood-brain barrier ma...

Medicinal plants are an integral part of African culture, one of the oldest and most diverse in the world. In South Africa, 21st century drug therapy is used side-by-side with traditional African medicines to heal the sick. While plants have been used in African medicine to treat fever, asthma, con...

Using a radically new strategy featuring radioactive "guided missiles," researchers at the Albert Einstein College of Medicine of Yeshiva University have successfully targeted and destroyed human immune cells infected with HIV, the virus that causes AIDS.
"This study in mice supports the idea th...

Scientists at the University of California, San Diego and Yale University have discovered that a natural protein produced by Bacillus thuringiensis, a bacterium sprayed on crops by organic farmers to reduce insect damage, is highly effective at treating hookworm infections in laboratory animals.
...

(Philadelphia, PA) - Over the last several months, the labs of Yale Goldman, MD, PhD, Director of the Pennsylvania Muscle Institute at the University of Pennsylvania School of Medicine, and Erika Holzbaur, PhD, Professor of Physiology, have published a group of papers that, taken together, show pro...

According to recent estimates, hepatitis has become a worldwide health problem, affecting millions of people in the U.S. and abroad. Researchers are experimenting with combinations of anti-inflammatory medicines like interferons to improve hepatitis symptoms. In research presented today at Digest...

University of Minnesota researchers have discovered how a prevalent fungal pathogen that causes 10,000 deaths per year in the United States overcomes the effects of antifungal drugs by duplicating a section of one of its chromosomes.
Candida albicans, a type of yeast present in 80 percent of hu...

A small protein in the brain that has only recently been discovered and, paradoxically, induces both profound wakefulness and a less anxious state, may represent a novel target for the treatment of psychotic behavior and schizophrenia, according to new research presented at the 6th International Co...

A revolutionary dissolvable scaffold for growing new areas of skin could provide a safer, more effective way of treating burns, diabetic ulcers and similar injuries.
This ultra-fine, 3-dimensional scaffold, which is made from specially developed polymers, looks similar to tissue paper but has fi...

For Dr. Sydney Finegold, research is like reading a really good mystery or detective story.
"But it is real life and one can see the results in one's own patients," he said. "So, one can have great fun while accomplishing worthwhile things."
With a grant from the Department of Defense, Fineg...

In their latest finding on the brain's role in controlling appetite and weight, researchers at the Albert Einstein College of Medicine have shown that reducing levels of fatty acids in the hypothalamus causes rats to overeat and become obese. Their results suggest that restoring fatty-acid levels i...

Understanding macrophages could lead to ways to prevent HIV-associated dementia
Bacteria-eating cells that generally fight infection may cause dementia in HIV patients, University of Florida and University of California at San Francisco researchers have found.
Macrophages, long-living white bl...

For years, sedatives have been the gold standard for treating newborns suffering from opiate withdrawal. However, new research suggests that opiates themselves are superior to sedatives for treating infants born to women who used heroin or methadone while pregnant.
Opiates appear to better "ameli...

When it comes to the deadly skin cancer melanoma, studying functional tissue rather than cell lines may better provide insight into the disease's development, according to new research from a Howard Hughes Medical Institute predoctoral fellow at Stanford University School of Medicine.
Though mult...

A team of researchers, led by Steven A. Rosenberg, M.D., at the National Cancer Institute, part of the National Institutes of Health, have found that patients with advanced melanoma who had not responded to previous therapies experienced a significant reduction in the size of their cancers as a res...

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