Example sentences for:
acly

Although ACC was not regulated at the transcriptional level, cytoplasmic citrate (generated from the Acly reaction) is an allosteric activator of ACC, so less cytoplasmic citrate would lead to less activation of ACC [ 45 ] . Transcript levels of hepatic acetyl CoA synthetase 1 AMP forming (acetate:CoA ligase AMP forming; Acas1) were consistently down regulated by LC-PUFA (-2.

It has previously been shown that the Acly gene in human cultured hepatic cells has a regulatory region from -61 to -49 in the 5' flanking region similar to that of Fasn, which is responsive to insulin and LC-PUFA [ 44 ] . In the present experiment, there was coordinated down regulation of both Acly (between -1.