Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology Similar to depression, anxiety disorders have also been related to metabolic and cardiovascular disorders. Does inflammation provide the connection between anxiety and these physical disorders? What are the possible relationships … Continue reading →

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology Fear- and anxiety-associated problems have been related to inflammation. As evidences, pro-inflammatory biomarkers have been found to be associated with affective behaviors (Michopoulos et al., 2017). For example, in mental … Continue reading →

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology Patients with terminal cancer are often troubled with fatigue (Rodrigues et al., 2016). Studies on the mechanisms would be helpful for improving the quality of life of the patients. A … Continue reading →

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology Anxiety and depression have been related to the higher levels of inflammation among those with obesity. This group of people may also have the higher risks of cardiovascular disease (CVD) … Continue reading →

Breast cancer survivors often have continuous psychological disorders such as anxiety and depression. Such mood problems may be caused by stress, and affect the quality of life (Pyter et al., 2017). Neuroinflammation may have a critical role in the mood … Continue reading →

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology The discoveries in psychoneuroimmunology (PNI) need to be translated into clinical care and better quality of life for patients. Such translational efforts are especially meaningful for the treatment of neuropsychiatric … Continue reading →

Inflammation, immune dysfunctions, and abnormal cytokine levels have been closely related to psychiatric disorders among adult patients in recent studies in psychoneuroimmunology (PNI). How about the associations between cytokine concentrations and psychosocial stress in children and adolescents (C&A)? A recent … Continue reading →

Mind-body interventions such as Tai Chi, Qigong, yoga, and meditation have been found to improve the quality of life. Recent studies have shown that these methods may affect the biological activities especially inflammation. A meta-study of 26 trials about mind-body … Continue reading →

Recent development in translational medicine provides a connection between basic scientific studies and clinical practice. Such an initiative may support the patient-centered objectives in both research and clinical environments. It may also improve the drug discovery procedure by allowing for … Continue reading →

The post-genomic research based on large cohorts of preclinical studies have produced multi-dimensional genetic and transcriptomic data sets. The revelation of the molecular pathways and cellular networks associated with various diseases may promote the systems biology studies of the onset … Continue reading →

The development in high-throughput (HTP) technologies and computational biology may help define the next generation of biomarkers. By providing an integrative viewpoint, systems biology may improve the understanding of the complexity in biological systems. The assemblage of interacting molecular elements … Continue reading →

Although biomarkers have been considered more and more important, it is still very difficult to identify and validate effective and useful biomarkers. The obstacles in the biomarker identification include both technical and theoretical reasons. For example, methods for identifying pathology-type … Continue reading →

Seasonal allergic rhinitis (SAR) is not just a commonly seen health problem in certain seasons. It is also a risk factor that can lead to asthma among many people. Nasal allergies can promote bone-marrow eosinophil generation through cytokines such as … Continue reading →

Neuropsychiatric (NP) disorders such as autism spectrum disorders (ASD) are the leading causes of disability around the world. However, because of their complexity, the etiology and pathophysiology of NP diseases are still mostly unknown. Such complexity may be caused by … Continue reading →

The identification of biomarkers is becoming more and more important in biomedicine, especially for the clinical practice. This is because biomarkers often contain valuable information about the pathology of the diseases such as cancers. Such information is useful for better … Continue reading →

Decades of scientific studies have demonstrated the essential role of the immune system in cancer pathology and clinical treatment. The immune system may regulate the growth of tumors via the complex interactions among molecules, genes, cells, and organs. The elucidation … Continue reading →

The new field of “skinomics” refers to the use of systems biology and “omics” approaches in the studies of the skin and dermatology. For example, high-through put (HTP) methods such as microarrays have been applied to identify biomarkers including transcriptional … Continue reading →

With the development of systems biology, bioinformatics, ‘omics’ studies, more and more discoveries are made in the disorders including cardiovascular diseases and cancer. However, although sometimes ignored, other common illnesses with high incidences including skin diseases also need more assessments … Continue reading →

Many chronic diseases are age-associated, including Alzheimer’s disease, cardiovascular disease, type 2 diabetes, and cancer. The elevating incidence of these disorders asks for the better understanding of the associations between the aging process and various diseases. With the increasing life … Continue reading →

Atherosclerosis involves a gradual process of inflammation with the stiffening of the arterial wall. This inflammatory condition can be caused by many factors, including elevated cellularity, lipid accrual, cellular debris, as well as extracellular substances (De Leon et al., 2015). … Continue reading →

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