Colts vs. 49ers: Live Score, Highlights and Analysis

The Indianapolis Colts came roaring into Candlestick Park and shut down the San Francisco 49ers with a balanced offensive attack, coupled with a disciplined, fundamental approach on defense.

The 49ers drop to 1-2, losing their second consecutive game for the first time under head coach Jim Harbaugh. There were more injuries and a serious failure to devise and execute a potent offensive game plan.

The Niners look to be completely unraveling here early in 2013 and only have three days to get a laundry list of problems corrected before facing off against the division rival St. Louis Rams on Thursday Night Football.