Individuals with major depressive disorder (MDD) often ruminate about past experiences, especially those with negative content. These repetitive thoughts may interfere with cognitive processes related to attention and conflict monitoring. However, the temporal nature of these processes as reflected in event-related potentials (ERPs) has not been… (More)

Systems theory has long been used in psychology, biology, and sociology. This paper applies newer methods of control systems modeling for assessing system stability in health and disease. Control systems can be characterized as open or closed systems with feedback loops. Feedback produces oscillatory activity, and the complexity of naturally occurring… (More)

Alcohol cue reactivity, operationalized as a classically conditioned response to an alcohol related stimulus, can be assessed by changes in physiological functions such as heart rate variability (HRV), which reflect real time regulation of emotional and cognitive processes. Although ample evidence links drinking histories to cue reactivity, it is unclear… (More)

Cannabis use and depressive disorders are thought to impair cognitive performance and psychosocial functioning. Both disorders co-occurring may compound the negative effects of these diagnoses. In this study, the authors used the California Computerized Assessment Package as the cognitive performance measure and the Addiction Severity Index as the… (More)

This investigation sought to validate a stimulus set previously adapted by expert consensus from the International Affective Picture System to be unpleasant and evocative to individuals with borderline personality disorder (BPD). This set was rated as significantly more arousing by 22 individuals diagnosed with BPD compared to 22 healthy controls, though… (More)

Neuropsychological and cognitive deficits are observed in the majority of persons with alcohol and drug use disorders and may interfere with treatment processes and outcomes. Although, on average, the brain and cognition improve with abstinence or markedly reduced substance use, better understanding of the heterogeneity in the time-course and extent of… (More)

Alcohol dependence (AD) is resistant to treatment and many patients relapse within the first year following care. There is a need to better understand specific factors that predict and moderate treatment response to help in the formulation of improved treatments for AD. One promising individual difference factor that is thought to influence AD treatment… (More)