Application Information: EIF3D antibody

Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.

Predicted Target Size

64 kDa (note)

Form Supplied

Liquid

Purification

Purified by affinity chromatography

Specifications: EIF3D antibody

Full Name

eukaryotic translation initiation factor 3 subunit D

Background

Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. [provided by RefSeq, Jul 2008]