Physical symptoms and components of labor tasks associated with upper limb disability among working breast cancer survivors.io FF
Abstract
BACKGROUND: Each year, the number of breast cancer (BC) cases increases in Brazil and worldwide. In addition, BC affects women of working age who need to resume their jobs after treatments. This is an observational, cross-sectional study that investigated the association of physical symptoms and work tasks with upper limb disability and return to work in BC survivors.
METHODS: Sociodemographic, labor, clinical and surgical aspects, and physical incapacity of the upper limbs of 62 women diagnosed with BC were evaluated through a questionnaire of our own and the disability of the arm, shoulder, a...Source: Breast Cancer - August 27, 2019 Category: Cancer & Oncology Authors: de Souza Cunha N, Zomkowski K, Fernandes BL, Sacomori C, de Azevedo Guimarães AC, Sperandio FF Tags: Breast Cancer Source Type: research

Clinical application of ceramide in cancer treatment. Abstract
Development of innovative strategies for cancer treatment is a pressing public health issue. Despite recent advances, the mechanisms of cancer progression and the resistance to cancer treatment have not been fully elucidated. Sphingolipids, including ceramide and sphingoshin-1-phosphate, are bioactive mediators that regulate cancer cell death and survival through the dynamic balance of what has been termed the 'sphingolipid rheostat'. Specifically, ceramide, which acts as the central hub of sphingolipid metabolism, is generated via three major pathways by many stressors, including anti-cancer treatments, ...Source: Breast Cancer - April 8, 2019 Category: Cancer & Oncology Authors: Moro K, Nagahashi M, Gabriel E, Takabe K, Wakai T Tags: Breast Cancer Source Type: research