Atopical dermatitis (AD) or constitutional eczema is a chronic pruritic inflammatory skin disorder. This is a frequent ailment since it affects approximately 20% of children. The outcome is usually favourable with total regression in the majority of cases at around the age of 3. Prevalence in adults is currently around 4%. This is a multifactor illness associating a particular genetic makeup and the action of environmental factors. These environmental factors could explain an increasing incidence of the ailment and an unequal distribution in the world since this ailment currently concerns in particular “developed” countries. The physiopathology is becoming discussed less and less.

AD is the clinical expression of an immune malfunctioning of unknown origin that makes the patient sensitive to the most commonplace constituents of environment such as inhalation allergens, foods, but also stress. The immune system is considered to be hyperactive, causing an exacerbation of the responses to molecules, even commonplace, in the environment.

- From the therapeutic point of view, several possibilities are offered: it is possible to act on the information by prescribing dermocorticoids. - Some authors recommend the strict avoidance of any allergens identified or changes of food intake, but this attitude is difficult to apply in practice. - It is also possible to modulate the immune reactions by the use of local or general immunosuppressors.

Platform:

OvidFrançais

Publisher: Wolters Kluwer France SA

Product Type: Book

ISBN: 978-2-704-01223-7

Specialty:

Dermatology

Language: French

Edition: 1st

Pages: 0

Illustrations: 0

Year: 0

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