Diseases and Conditions

Rheumatoid Arthritis

What is rheumatoid arthritis?

Rheumatoid arthritis is a chronic disease that causes inflammation of the joints. The inflammation can become so severe that
the function and appearance of the hands, as well as other parts of the body, can become affected. In the hand, rheumatoid
arthritis may cause deformities in the joints of the fingers, making movement difficult. Lumps, known as rheumatoid nodules,
may form over small joints in the hands and the wrist. Juvenile rheumatoid arthritis (JRA) is a form of arthritis in children
ages 16 or younger that causes inflammation and stiffness of joints for more than six weeks. Unlike adult rheumatoid arthritis,
which is chronic and lasts a lifetime, children often outgrow JRA. However, the disease can affect bone development in the
growing child.

What causes rheumatoid arthritis?

The exact cause of rheumatoid arthritis is not known. Rheumatoid arthritis is an autoimmune disorder, which means the body's
immune system attacks its own healthy cells and tissues. The response of the body causes inflammation in and around the joints,
which then may lead to a destruction of the skeletal system. Rheumatoid arthritis also may have devastating effects to other
organs, such as the heart and lungs. Researchers believe certain factors, including heredity, may contribute to the onset
of the disease.

Rheumatoid arthritis affects more women than men (70 percent of persons with rheumatoid arthritis are women). The disease
most often occurs between the ages of 30 and 50.

What are the symptoms of rheumatoid arthritis?

The joints most commonly affected by rheumatoid arthritis are in the hands, wrists, feet, ankles, knees, shoulders, and elbows.
The disease typically causes inflammation symmetrically in the body, meaning the same joints are affected on both sides of
the body. Symptoms of rheumatoid arthritis may begin suddenly or gradually. The following are the most common symptoms of
rheumatoid arthritis in the hands. However, each individual may experience symptoms differently. Symptoms may include:

Pain

Stiffness, especially in the morning

Swelling over the joints

Decreased movement

Pain that is worse with movement of the joints

Bumps may be noted over the small joints

Difficulty performing activities of daily living (ADLs), such as tying shoes, opening jars, or buttoning shirts

Decreased ability to grasp or pinch

Fatigue

Occasional fever

The symptoms of rheumatoid arthritis may resemble other medical conditions or problems. Always consult your doctor for a diagnosis.

How is rheumatoid arthritis diagnosed?

Diagnosis of rheumatoid arthritis may be difficult in the early stages because symptoms may be very subtle and go undetected
on X-rays or blood tests. In addition to a complete medical history and physical examination, diagnostic procedures for rheumatoid
arthritis may include the following:

Joint aspiration. This involves a removal of fluid from the swollen bursa to exclude infection or gout as possible causes.

Biopsy (of nodules tissue). A procedure in which tissue samples are removed (with a needle or during surgery) from the body
for examination under a microscope to determine if cancer or other abnormal cells are present.

Blood tests. These tests are done to detect certain antibodies, called rheumatoid factor, and other indicators for rheumatoid
arthritis.

Treatment for rheumatoid arthritis

Specific treatment for rheumatoid arthritis will be determined by your doctor based on:

Your age, overall health, and medical history

Extent of the condition

Your tolerance for specific medications, procedures, or therapies

Expectations for the course of the condition

Your opinion or preference

Treatment may include:

Medications. Some medications may be used for pain relief, other medications will be used to treat inflammation, and finally some medications
will be used to slow the disease from progressing. Depending on your symptoms and preferences, your doctor may treat you with
one or more types of treatments.

Splints. Splints may be used to help protect the joints and strengthen the weak joints.

Physical therapy. Physical therapy may be used to help increase the strength and movement of the affected areas.

Surgery. Surgery may be performed if the above treatment options fail. The decision for surgery should be made in consultation with
your doctor. Repair or reconstruction of the hand and wrist can be performed in a variety of ways, including the following:

Surgical cleaning. This option may be performed on patients with rheumatoid arthritis, or other types of hand arthritis. Inflamed and diseased
tissues within the hands can be removed to help increase function.

Joint replacement. This type of surgery, also called arthroplasty, may be used in cases of severe arthritis of the hand. This option may be performed
on older patients with a lower activity level. Joint replacement may provide a decrease in pain and an increase in function
of the hands and fingers. This involves replacing a joint that has been destroyed by the disease process with an artificial
joint. This artificial joint may be made out of metal, plastic, silicone rubber, or the patient's own body tissue (such as
the tendon).

Joint fusion. This option usually involves removing the joint and fusing together two ends of bones. This makes one large bone without a
joint. This option is usually used on patients with advanced arthritis. After the fusion of the bone, there is an elimination
of movement in the fused joint.

It is important to remember that surgery does not correct the underlying disease. It only helps correct the deformities caused
by the disease. Rheumatoid arthritis can continue to cause problems in the hand, and may even require additional surgery.
Close follow-up with your doctor is required for optimal control of this disease.