Comic-Con 2011 took place in San Diego this weekend, and one devoted fan at the "Family Guy" panel discussion asked a question that has been on people's minds for years: Who can understand Stewie when he talks, and who can't?

Creator Seth MacFarlane and writer/executive producer Steve Callaghan both take swings at trying to explain the delicate science, but the answer basically boils down to "whoever we feel like."