Browse our anti-IRF9 (IRF9) Antibodies

Full name:

anti-Interferon Regulatory Factor 9 Antibodies (IRF9)

On www.antibodies-online.com are 74 Interferon Regulatory Factor 9 (IRF9) Antibodies from 21 different suppliers available. Additionally we are shipping IRF9 Kits (4) and IRF9 Proteins (4) and many more products for this protein. A total of 88 IRF9 products are currently listed.

IL6 (show IL6 Antibodies) is an inducer of IRF9 expression in prostate cancer and a sensitizer for the antiproliferative effects of IFNalpha2 (show IFNA2 Antibodies).

The hepatitis C virus (HCV) non-structural 5A (NS5A) protein, which is known to modulate the IFN response, competes with IRF9 for CypA (show PPIA Antibodies) binding and can prevent the formation of IRF9-CypA (show PPIA Antibodies) complexes.

IFN-alpha (show IFNA Antibodies)/beta is able to drive the formation of a Stat2 (show STAT2 Antibodies) and IRF-9 complex that drives the expression of a subset of IFN-stimulated genes, but with substantially delayed kinetics.

IRF9 Antigen Profile

Antigen Summary

Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.