42 products are now successfully validated

The antibody for the detection of Cadherin 5 (CDH5) has now been successfully validated for immunofluorescence. A clear signal of the calcium-depending adhesion molecule was achieved in murine liver tissue while murine brain tissue (known to be negative for cadherin 5) remained unstained.

Cadherin 5 (also called CD144) is a vascular endothelial cadherin. This type of cadherins appears at the contact site of endothelial cells. They are functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, and additional they fundction also as a desmosome.

In mid 2013 the "Independent Validation Initiative" started as a partnership between Science Exchange and antibodies-online.com. The project aims to enable scientists to select products (presently antibodies or ELISA kits) of their interest to be validated by labs from top academic research institutes.

Since we started the initiative we have successfully validated 42 products. The first was a anti-Fibrinogen antibody, followed by a couple of other interesting antibodies and ELISA kits. The latest succesfully validated product is an antibody for the detection of Cadherin 5 (CDH5). A few more products are currentlly being validated.

If you are interested in having a product validated, you can simply click the "Request validation" button on the product site. When requesting a validation you can specify the application the product should be validated for. Validation is free for all customers and costs will be covered by the respective supplier.
Here is a full list of successfully validated products: