Dormosedan® (detomidine hydrochloride) is indicated for use as a sedative and analgesic to facilitate minor surgical and diagnostic procedures in mature horses and yearlings.

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Extended Information:

DORMOSEDAN® (detomidine hydrochloride) is a nonnarcotic, synthetic (alpha-2 adrenoreceptor agonist) equine sedative/analgesic that contains the active ingredient detomidine hydrochloride. DORMOSEDAN can be used safely for a variety of minor surgical and diagnostic procedures.

Approved Uses

DORMOSEDAN is approved for:

Use as a sedative and analgesic to facilitate minor surgical and diagnostic procedures in mature horses and yearlings.

For Sedation: Administer DORMOSEDAN IV or IM at the rates of 20 or 40 mcg detomidine hydrochloride per kg of body weight (0.2 or 0.4 mL of DORMOSEDAN per 100 kg or 220 lb), depending on the depth and duration of sedation required. Onset of sedative effects should be reached within 2–4 minutes after IV administration and 3–5 minutes after IM administration. Twenty mcg/kg will provide 30–90 minutes of sedation, and 40 mcg/kg will provide approximately 90 minutes to 2 hours of sedation.

For Analgesia: Administer DORMOSEDAN IV at the rates of 20 or 40 mcg detomidine hydrochloride per kg of body weight (0.2 or 0.4 mL of DORMOSEDAN per 100 kg or 220 lb), depending on the depth and duration of analgesia required. Twenty mcg/kg will usually begin to take effect in 2–4 minutes and provide 30–45 minutes of analgesia. The 40 mcg/kg dose will also begin to take effect in 2–4 minutes and provide 45–75 minutes of analgesia.

For Both Sedation and Analgesia: Administer DORMOSEDAN IV at the rates of 20 or 40 mcg detomidine hydrochloride per kg of body weight (0.2 or 0.4 mL of DORMOSEDAN per 100 kg or 220 lb), depending on the depth and duration of sedation and analgesia required.

Before and after injection, the animal should be allowed to rest quietly.

Precautions

Careful consideration should be given prior to administration of DORMOSEDAN to horses approaching or in endotoxic or traumatic shock, to horses with advanced liver or kidney disease, or to horses under stress from extreme heat, cold, fatigue, or high altitude.

Protect treated horses from temperature extremes.

Some horses, although apparently deeply sedated, may still respond to external stimuli.

Routine safety measures should be employed to protect practitioners and handlers. Allowing the horse to stand quietly for 5 minutes before administration and for 10–15 minutes after injection may improve the response to DORMOSEDAN.

DORMOSEDAN is a potent á2-agonist, and extreme caution should be exercised in its use with other sedative or analgesic drugs, for they may produce additive effects.

When using any analgesic to help alleviate abdominal pain, a complete physical examination and diagnostic work-up are necessary to determine the etiology of the pain.

Federal law restricts this drug to use by or on the order of a licensed veterinarian.