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Short answer: You are seeing the request to Skyhook Wireless because they have the geographic database that Apple uses for Core Location in the operating system.
Longer answer:
Skyhook Wireless is the company with the geographic database about WiFi access points that is used for the new location services (Core Location) in OS X Snow Leopard. Core ...

I always preferred NetLimiter over any other solution I've tried.
NetLimiter used to be only about bandwidth control and it still shines at that. But a personal firewall feature was added later on.
What primarily distinguishes it from the Windows firewall is that it will not allow any connection attempt to succeed before you decided how you want to handle ...

Have a look in the following locations for plist files that look like they are related to Little Snitch. They will most likely start with at.obdev :
/Library/LaunchAgents
/Library/LaunchDaemons
/System/Library/LaunchAgents
/System/Library/LaunchDaemons
~/Library/LaunchAgents
~/Library/LaunchDaemons
Move the offending files to a different location, reboot ...

As mentioned in another answer, locationd is the daemon (system process) responsible for Snow Leopard's new Core Location service, which uses the Skyhook WiFi location database to (attempt to) ascertain your location based on the WiFi access points your Mac "sees." However, disabling the "automatically update time zone" in Date and Time Preferences does NOT ...

There's no need to edit any files; just unload the service and delete its plist:
sudo launchctl unload /Library/LaunchDaemons/at.obdev.littlesnitchd.plist
sudo rm /Library/LaunchDaemons/at.obdev.littlesnitchd.plist

OK answers, but as a long time little snitch user, I think I have better possibilities for you :
1 - Zone Alarm : that i've been using for years and is very similar to little snitch (two way communication control).
2 - Outpost security suite: I hear good things of this product and a free version is available.
Have fun,

I'm not aware of of any CLI utility to solve your problem, but Little Snitch does allow for automatic approval of new requests within a specified time period. This may not be the best option for you, but it will get your app out to the Internet provided it's using an appropriate timeout.

Here's a good explanation of what you're probably witnessing from the forums at transmissionbt.com.
Basically, if you ever hit a tracker they're checking back with you, as well as any peers that may have learned about you from past relations. So even if you don't have any torrents currently loaded, they still know you as someone who may want to share ...

You need open terminal:
cd /private/var/db/launchd.db/com.apple.launchd
make a backup copy of overrides.plist (make sure it is there using the ls command)
sudo cp overrides.plist overrides.bak
open overrides.plist
sudo vim overrides.plist
Look for any Little Snitch UIAgent entries and remove them. Save. Close. Reboot.
(this should also remedy the ...

I like Kaspersky Internet Security for Windows, it lets me block by profile, giving some users full access, and others limited access, has a nice built in filter and you can modify this. I set it up on my home computer for the kids in about 5 minutes, including setting up the Windows User for them.

If it's specific tracking websites, you may want to look at Ghostery. There are Ghostery plugins for Mozilla and Chrome and IE as well.
You can also try Adblock which runs on Mozilla and Chrome as well. You can list all elements on a page, and block any element specifically, or by simple expressions.
Obviously this only works on users that install these ...

Sorry, but Zone Alarm is nothing like Little Snitch – it fails to show full activity of a program's connection. It just says "Connecting to 127.0.0.1" or "Program attempting to connect to the internet". Zone Alarm Paid version has more information like Little Snitch.
You could always use netstat and Windows' built-in firewall. Just tell Windows Firewall ...

I've used as ZoneAlarm, as Comodo. But since I started using Jetico Personal Firewall, I have no more additional needs. It's very comprehensive and convenient firewall which is powerful enough for a professional! You may check it out by yourself: http://www.jetico.com/firewall-jetico-personal-firewall/
I have no idea why it's not so popular yet...

Another sophisticated firewall product is
Online Armor Free that can be downloaded from MajorGeeks.
This is a somewhat geeky but complete product that is also a
Host Intrusion Prevention System (HIPS).
From Best Free Firewall Protection :
It has a unique feature called "run safer" that allows you to
selectively set risky applications (web browsers, ...

Does it still happen after you completely close Chrome and restart?
If so:
Disable all your plugins / extensions / etc.
Go to chrome://net-internals/ in a new tab and capture the traffic. Find out any referrers, etc. which are triggering this traffic.
Kill whatever process is triggering the traffic from #2
If it still happens, complain on the user ...