The works listed will allow your students to further explore the theme
of The Effects of Isolation and other themes related to Ethan Frome:

Fiction
Davis, Owen and Donald. Ethan Frome: A Dramatization. New York:
Charles Scribner's Sons, 1936. Based on the novel. (average)

Hardy, Thomas. Jude the Obscure. Although the title character
of this English novel pursues his dreams of an education and a life
with the woman he loves, Jude Fawley is destroyed by a series of crushing
disappointments. (challenge)

Flaubert, Gustave. Madame Bovary. This famous French novel of
adultery portrays the life and death of an unhappy woman who tries and
fails to find romantic fulfillment in an affair. (challenge)