Human Calcium Binding Protein P22 (CHP) interaction partners

serum-independent activation of NHE1 (show SLC9A1 ELISA Kits) by bound CHP2 is one of the key mechanisms for the maintenance of high pH(i) and the resistance to serum deprivation-induced cell death in malignantly transformed cells

Calcium Binding Protein P22 (CHP) Antigen Profile

Antigen Summary

This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein shares similarity with calcineurin B and calmodulin and it is also known to be an endogenous inhibitor of calcineurin activity.