High-precision SHRIMP U-Pb dating was performed on zircon from quartz diorite and diabase in the Xinqiao Cu-S-Fe-Au deposit, Tongling ore district, Anhui. Zircon from quartz diorite yielded a 206Pb/238U age of (140.4±2.2) Ma, while the zircon age of diabase is relatively complex. Several Proterozoic zircon grains were found in diabase, which yielded 207Pb/206Pb ages of (2 261±14) Ma, (1 612±8) Ma, (919±12) Ma and (831±17) Ma. In addition, there is also a group of Early Paleozoic zircon grains, whose 206Pb/238U age is (443±13) Ma. The above new data give the information of the possible existence of Proterozoic basement in this district, and Yanshanian magmatism is of great significance for mineralization in the district.