Transurethral Agents - Erectile Dysfunction

Who should not use urethral suppositories?

Men should avoid using urethral suppositories if they are hypersensitive to alprostadil, have an abnormally-formed penis, or have been advised against sexual activity.

Men who have conditions that make them susceptible to long-lasting erections should also not use MUSE. Examples of such conditions include sickle cell anemia (or trait), leukemia, or multiple myeloma (tumor of the bone marrow).

A man using urethral suppositories should use a condom when having intercourse with a pregnant woman, as it is unclear how the medication may affect a developing fetus.