I was scheduled to deliver a lecture on picornaviruses to a virology class at Yale University this week, but had to cancel at the last minute. I prepared this screencast to make up for my absence.

The Picornaviridae is a family of non-enveloped, positive-strand RNA viruses which contains some well known viruses including poliovirus, rhinovirus, hepatitis A virus, enterovirus 71, and foot-and-mouth disease virus. In this lecture I cover basic aspects of picornavirus replication and pathogenesis, including attachment and entry, translation and protein processing, RNA synthesis, assembly and release, disease and immunization.