Two Propylhexedrine-Associated Fatalities: Benzedrine® Revisited

The Benzedrine® inhaler, long used as a local vasoconstrictor for nasal congestion, and at one time a readily available source of amphetamine, was replaced some years ago with the Benzedrex® inhaler, containing propylhexedrine. It was known that abuse had occurred with the prior constituent, but few toxic episodes and no fatalities have been documented with the latter agent. We have recently observed two deaths involving propylhexedrine which are the subject of this report.