BioTek offers many peripheral instruments and accessories to expand functionality and enhance assay workflows. Many peripheral instruments and modules are compatible with several different instruments, see the list here.

BioTek's highly trained sales and service professionals are experts in life science instrumentation. They will guide you through your decision process and help you select the proper equipment for your application, assist with installation in your lab, and train your staff on the use of the instrumentation.

November 14, 2018 - BioTek Instruments extends congratulations to Dr. Benjamin R. King as this year’s recipient of the Norman R. Alpert Research Prize. The honor, which includes an engraved plaque and cash award, was announced at the Larner College of Medicine Research Day event held at The University of Vermont (UVM) on October 30, 2018. Weiterlesen

October 22, 2018 - BioTek is pleased to congratulate its President and CEO, Briar Alpert, for receiving the 2018 Alumni Achievement Award from the University of Vermont (UVM) Alumni Association. The award recognizes alumni demonstrating outstanding commitment to Vermont, the University, and the local community. Weiterlesen

October 16, 2018 - BioTek has released a Peltier Cooling Module for the Cytation™ Cell Imaging Multi-Mode Readers. The compact module keeps internal temperature rise to less than one degree over ambient, regardless of fluctuations from external and internal factors. The module helps maintain and optimize stability for more consistent data in assays run at ambient temperature. The module also quickly reduces internal temperature after incubated assays for efficient transitions between multiple applications with different temperature requirements. Weiterlesen

March 2 - 6, 2019

Booth #404

Baltimore Convention Center

Nothing can speak to the experience you'll encounter with BioTek like stories from our customers themselves. Customer satisfaction is our top priority. From Engineering to Manufacturing to Sales and Support, BioTek employees around the world are dedicated to providing the best product and best customer experience in the industry.

At BioTek we feel passionately and genuinely that our employees are our greatest asset. We continue to build our already impressive team having doubled our global workforce in the last five years. With our headquarters in the beautiful Green Mountains of Vermont, USA, we also have regional offices around the world.

If you're interested in becoming part of our amazing team, check out our list of job openings today!

As a prospective partner, BioTek can help you achieve your sales and market penetration by providing a unique blend of products, service, support, training, co-marketing and quality assurance designed to meet your customers’ requirements while you remain focused on your core business.

At BioTek we feel passionately and genuinely that our employees are our greatest asset. We continue to build our already impressive team having doubled our global workforce in the last five years. With our headquarters in the beautiful Green Mountains of Vermont, USA, we also have regional offices around the world.

If you're interested in becoming part of our amazing team, check out our list of job openings today!

Abstract

Nonalcoholic steatohepatitis, or NASH, is a common, often “silent” liver disease that resembles alcoholic liver disease, but occurs in people who drink little or no alcohol. The etiology of the disease is the accumulation of neutral lipid droplets within the liver cell, which can be tracked with Nile red staining. To date, research in this area has suffered from the lack of a suitable human cell model as well as the means to automate the assay process and subsequent microscopic image analysis.

We have shown here that liver cells, when exposed to various concentrations of a mixture of oleic and palmitic free fatty acids (FFA), accumulated intracellular neutral lipids in a dose dependent fashion up to 1 mM FFA treatment. Doses of FFA higher than 1 mM resulted in cell death and the loss of cells. Following treatment, cells were fixed and stained with Nile red (lipid stain) and DAPI (nuclear stain) using automation. Fixed and stained cells were digitally imaged with a Cytation™ 5 Imaging Multi-Mode Reader using a 10x or 20x objective. Uptake of FFA and conversion to neutral lipid droplets was monitored over time using a BioSpa™ 8 Automated Incubator to present plates to a MultiFlo™ FX Multi-Mode Dispenser at periodic times after the addition of FFA in order to stop the reaction by adding fixative to the cells. Automated Image analysis was then used to determine the percentage of cells positive for neutral lipids.