Research Interests: Neuron and Cardiac Cell Modeling. Development of a Neurally Controlled Human Cardiovascular and Respiratory System (H-CVRS) Model. Medical Imaging.

Research is centered on the area of Computational Biology and Medicine. Dr. Clark's Laboratory develops detailed mechanistic models of biological processes on several levels of scale: from molecular, cellular and tissue modeling to the development of interactive multiple-organ system models. Examples of cellular models include cardiac cell and neuron modeling with mechanistic ion channel descriptions and modulation via second messengers. At the multiple-organ level, work is focused on the development of large-scale models of the human cardiovascular and respiratory systems, as they interact and are controlled by the central nervous system. This later H-CVRS model has been applied to the study of a variety of problems in critical care medicine including congestive heart failure.

Special Award, Houston Society for Engineering in Medicine and Biology (7 February 2008)

Proclamation:, Mayor Bill White, City of Houston (February 7, 2008)

General Conference Co-chair, 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE/EMBS), IEEE Engineering in Medicine and Biology Society (23-26 August 2007)

Program Co-Chair (with L.V. McIntire, Rice University) of the Joint EMBS/BMES Conference on Engineering in Medicine and Biology, to be held in Houston, TX 23-26 Oct. 2002., IEEE Engineering in Medicine and Biology Society (EMBS) and Biomedical Engineering Society (BMES).

Program Co-Chair (with L.V. McIntire, Rice University) of the Joint EMBS/BMES Conference on Engineering in Medicine and Biology, to be held in Houston, TX 23-26 Oct. 2002., Engineering in Medicine and Biology Society (EMBS) and Biomedical Engineering Society (BMES)