Apollo’s Hegemony Resveratrol Plus is a dietary supplement that contains resveratrol, grape seed extract and coenzyme Q10 (CoQ10). All three present strong antioxidant and anti-inflammatory properties and have beneficial effects on the cardiovascular system.

Resveratrol is a natural polyphenol abundant in purple grape skins and red wine and has been reported to have multiple health benefits, particularly anti-inflammatory, antioxidant cardioprotective and antiaging. Resveratrol may target many pathways or proteins including COX-1, peroxisome proliferator-activated receptor (PPAR) and endothelial nitric oxide synthase (eNOS).

Resveratrol has been reported to be potent activator of the SIRT1 genes, which are associated with a longer lifespan, increased insulin sensitivity, increased AMPK activity and increased mitochondrial function. Therefore resveratrol may contribute to reducing body weight gain, improving insulin sensitivity and promoting cardiovascular health.

Grape seed extract is a source of procyanidins. Clinical trials have shown that grape seed extract can reduce blood pressure, decrease heart rate and reduce leg swelling. Partially due to its ability to preserve nitric oxide (NO), synergistically with resveratrol and CoQ10. NO is a small molecule responsible for vasodilation, therefore it improves blood flow and inhibits platelet adhesion.

Coenzyme Q10 is an endogenously synthesized lipid-soluble micronutrient/vitamin-like substance found in human body. It is a key component in the electron transport chain of the mitochondria, where the energy is produced in the form of ATP. CoQ10 is also a potent antioxidant that scavenges free radicals and provides protection to cells from oxidation.

It is believed that the best time for taking resveratrol is at bedtime or at least half an hour after a meal because this is when sirtuins show the highest activity.

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