A team of scientists just won a battle in the war against antibiotic-resistant "superbugs"—and only time will tell if their feat is akin to the bacterial "Battle of Gettysburg" that turns the tide toward victory. They won this particular battle, or at least gained some critical intelligence, not by designing a new antibiotic, but by interfering with the metabolism of the bacterial "bugs" – E. coli in this case – and rendering them weaker in the face of existing antibiotics, as reported today in Nature Biotechnology.