Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

¨ Rule 13d-1(b)

x Rule 13d-1(c)

¨ Rule 13d-1(d)

*

The remainder of this cover page shall be filled out for a reporting persons initial filing on this form with respect to the subject class of securities, and for
any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

The information
required on the remainder of this cover page shall not be deemed to be filed for the purpose of Section 18 of the Securities Exchange Act of 1934 (Act) or otherwise subject to the liabilities of that section of the Act but
shall be subject to all other provisions of the Act (however, see the Notes).

CUSIP No. 88034G109

1)

Names of Reporting Persons.

CELGENE CORPORATION

2)

Check the Appropriate Box if a
Member of a Group (See Instructions)

(a) ¨ (b) ¨

3)

SEC Use Only

4)

Citizenship or Place of
Organization

Delaware

NUMBER OF

SHARES

BENEFICIALLY

OWNED BY

EACH

REPORTING

PERSON

WITH:

5.

Sole Voting Power

A Senior Secured Convertible Note with a principal amount of
$5,002,283.10, convertible into shares of Common Stock of the Issuer, and warrants to purchase 10,228,310 shares of Common Stock of the Issuer*

* The conversion of the note and the exercise of the warrants are limited to that number of shares of
Common Stock of the Issuer that, when aggregated with the holders existing ownership of Common Stock of the Issuer, would result in such holder, together with related persons or entities, owning no more than 9.985% of the total number of
outstanding shares of Common Stock of the Issuer.

6.

Shared Voting Power

-0-

7.

Sole Dispositive Power

A Senior Secured Convertible Note with a principal amount of
$5,002,283.10, convertible into shares of Common Stock of the Issuer, and warrants to purchase 10,228,310 shares of Common Stock of the Issuer*

* The conversion of the note and the exercise of the warrants are limited to that number of shares of
Common Stock of the Issuer that, when aggregated with the holders existing ownership of Common Stock of the Issuer, would result in such holder, together with related persons or entities, owning no more than 9.985% of the total number of
outstanding shares of Common Stock of the Issuer.

8.

Shared Dispositive Power

-0-

9)

Aggregate Amount Beneficially Owned by Each Reporting Person

A Senior Secured Convertible Note with a principal amount of $5,002,283.10, convertible into shares of Common Stock of the Issuer, and
warrants to purchase 10,228,310 shares of Common Stock of the Issuer*

* The conversion of the note and the exercise of the warrants are limited to that number of shares of Common Stock of the Issuer that, when aggregated with the holders existing ownership
of Common Stock of the Issuer, would result in such holder, together with related persons or entities, owning no more than 9.985% of the total number of outstanding shares of Common Stock of the Issuer.

A Senior Secured Convertible Note with a principal amount of $5,002,283.10, convertible into shares of Common Stock of
the Issuer, and warrants to purchase 10,228,310 shares of Common Stock of the Issuer*

* The conversion of the note and the exercise of the warrants are limited to that number of shares of
Common Stock of the Issuer that, when aggregated with the holders existing ownership of Common Stock of the Issuer, would result in such holder, together with related persons or entities, owning no more than 9.985% of the total number of
outstanding shares of Common Stock of the Issuer.

(b)

Percent of class:

9.985%. Such percentage is based upon 2,466,914 outstanding shares of Common Stock of the Issuer.

(c)

Number of shares as to which the person has:

(i)

Sole power to vote or to direct the vote:

A Senior Secured Convertible Note with a principal amount of $5,002,283.10, convertible into shares of Common Stock of the Issuer,
and warrants to purchase 10,228,310 shares of Common Stock of the Issuer*

* The conversion of the note and the exercise of the warrants are limited to that number of shares of Common Stock of the Issuer that, when aggregated with the holders existing ownership
of Common Stock of the Issuer, would result in such holder, together with related persons or entities, owning no more than 9.985% of the total number of outstanding shares of Common Stock of the Issuer.

(ii)

Shared power to vote or to direct the vote:

- 0-

(iii)

Sole power to dispose or to direct the disposition of:

A Senior Secured Convertible Note with a principal amount of $5,002,283.10, convertible into shares of Common Stock of the Issuer,
and warrants to purchase 10,228,310 shares of Common Stock of the Issuer*

* The conversion of the note and the exercise of the warrants are limited to that number of shares of Common Stock of the Issuer that, when aggregated with the holders existing ownership
of Common Stock of the Issuer, would result in such holder, together with related persons or entities, owning no more than 9.985% of the total number of outstanding shares of Common Stock of the Issuer.

(iv)

Shared power to dispose or to direct the disposition of:

- 0-

ITEM 5.

OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS

Not applicable.

ITEM 6.

OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON

Not applicable.

ITEM 7.

IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY

Not applicable.

ITEM 8.

IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP

Not applicable.

ITEM 9.

NOTICE OF DISSOLUTION OF GROUP

Not applicable.

ITEM 10.

CERTIFICATION.

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or
with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.

Signature

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.