The drama, which tells seven separate stories, follows a week in the lives of a group of morally challenged characters -- a movie executive, his wife, his mistress, a rock star, a vampire and a kidnapper. It is set in 1980s Los Angeles.

Ryder will play a newscaster who has just been dumped after a longtime affair with a married producer William Sloan.

Rourke will play Peter, an amoral former studio security guard who plots to kidnap a small child to sell to the leader of a Los Angeles cult.

Senator's Marco Weber will produce the picture, while Senator head of production Vanessa Coifman will executive produce. Principal photography will begin in October in Los Angeles.

Ryder next stars in "Welcome," directed by Kirsten Dunst, and has finished shooting on Daniel Waters' "Sex and Death 101," set for release next year. She is repped by WMA and attorney Barry Hirsch.

Rourke next appears in John Madden's "Killshot." He is repped by ICM and attorney Bill Sobel.