Corning TransportoCells are high-performance mammalian cells in a convenient, cryopreserved format that transiently overexpress individual human solute carrier (SLC) transporter proteins. The latest innovation was unveiled at the 10th Annual Meeting of the International Society for the Study of Xenobiotics (ISSX), Sept. 29 - Oct. 3 in Toronto.

“Culturing and maintaining transporter cell lines can be expensive and time-consuming, taking a week or more to prepare cells for assaying,” said Dr. Charles Crespi, Discovery Labware business director, Corning Life Sciences. “Corning TransportoCells can be thawed, plated and assayed in just two days with high-uptake ratios, delivering robust data while eliminating the time required to culture and maintain stable cell lines.”

The Corning TransportoCells were developed by leveraging Gentest™ technology obtained as part of Corning’s acquisition of Becton Dickinson’s Discovery Labware business in 2012. Corning TransportoCells complement Corning’s full range of cell culture and bioprocess solutions, including innovative vessels for research through scale-up; advanced cell culture surfaces to grow attachment-dependent and unattached cells; and a range of Corning cellgro® media, sera, and custom solutions for cell culture applications.

Corning TransportoCells features include:

• A cryopreserved format that provides flexibility for experimental planning • Cells that are readily available, can be stored onsite, and shipped globally • Cells that can be thawed, plated, and assayed in just two days • Robust results with equal, or greater than, 10-fold uptake ratios • Consistency with other mammalian cell-based models • Individual vials that contain 10 million cells and support one 24-well or one 96-well assay plate • All current USFDA and European Medicines Agency (EMA)-recommended SLC drug transporters

For companies looking to outsource their SLC Transporter Interaction Studies using Corning TransportoCells, Corning GentestSM Contract Research Services will also be available beginning in 2014. All assays are designed to meet regulatory agency recommendations.

Through acquisition and ongoing research and development investment, Corning now offers a more comprehensive range of premium and innovative laboratory products and solutions for a wide spectrum of life science applications. Corning’s trusted quality brands – backed by technical expertise – provide researchers with better ways to advance their research from the beginning of their process to the end. The family of brands includes Corning®, Falcon®, Corning cellgro®, PYREX®, Axygen®, and Gosselin™.

Corning TransportoCells are available to customers worldwide. To learn more about the new Corning TransportoCells or any Corning Life Sciences products, please contact a customer service representative at 1-800-492-1110 toll free in the United States; (+1) 1-978-442-2200 internationally; or visitwww.corning.com/lifesciences.

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