Background and purpose: Based on Janda’s theory of kinetic chain, dysfunction in one motor segment can affect other segments in the body. The purpose of the study was to determine the correlation between Low Back Pain (LBP) and foot overpronation in patients referred to Hazrat Rasool Hospital.

Materials and Methods: In this cross sectional study, 242 subjects were classified into two groups, LBP and healthy groups and evaluated for the duration and intensity of LBP, flexibility of trunk, foot overpronation (by Helbing sign and Navicular Drop test ) and ankle dorsiflexion range. The Independent sample t- test and Chi-Square test were conducted for statistical analysis of the data.

Results: A significant correlation between foot overpronation and LBP (p=0.001) was found in the study. There were significant relations between LBP intensity and foot overpronation

(p=0.001); between the history of LBP and foot overpronation (p=0.001) and also on the between foot overpronation and ankle dorsiflexion range (p=0.014).

Conclusion: The findings of this study indicate significant relations between the incidence, intensity and duration of LBP in patients with foot overpronation; also, the ankle dorsiflexion range was reduced in the subjects with foot overpronation.