Description:
This second volume continues with a focus on the state of the art
in genetic eye research in Asia and the Pacific. Though there has
been an explosion of information on genetic eye research in
western countries, more than sixty percent of the human genes
involved in eye diseases in the Asian and Pacific population
remain unknown. However, new efforts and a new awareness have
sparked important discussions on the subject, and new plans are
being implemented to discover the genes responsible for many eye
diseases in the population. The book reviews the latest findings;
its content ranges from genetic aspects of human migration to... more...

Description:
This case series book offers a practical and accessible approach
to psychiatry, addressing major clinical problems ranging from
psychosis to aging effects, each of which is tackled as it arises
in everyday settings. With its emphasis on everyday practice
strongly linked to underlying theory, the book combines clinical
knowledge with the realities of managing clinical problems, and
will provide a basis for developing sound analytical and
confident decision-making skills. Presenting different visions of
clinical psychiatry and expanding psychiatrists’ interventions by
integrating innovative neuroscience approaches such as... more...

Description: Adult neuropsychiatry is now a well-established field with numerous
reputable references. Practitioners who work with children
routinely note how references and practitioners knowledgeable in
the equivalent work in the pediatric world are rare. Child
psychiatrists and neurologists frequently work with individuals
struggling with these conditions and would strongly benefit from
such a reference that incorporates medical work-up,
psychopharmacological recommendations, family/support
recommendations and theoretical pathophysiology. Pediatricians and
developmental pediatricians often treat children with behavioral
and neuropsychiatric sequelae, but are... more...

Description: This book covers reliability assessment and prediction of new
technologies such as next generation networks that use cloud
computing, Network Function Virtualization (NVF), Software Defined
Network (SDN), Next Generation Transport, Evolving Wireless
Systems, Digital VoIP Telephony, and Reliability Testing techniques
specific to Next Generation Networks (NGN). This book introduces
the technology to the reader first, followed by advanced
reliability techniques applicable to both hardware and software
reliability analysis. The book covers methodologies that can
predict reliability using component failure rates to system level
downtimes. The book’s... more...

Description:
This book responds to the growing demand for a scientific
approach to the concept of startups, which are a manifestation of
the digital revolution and an innovation-driven economy. With a
focus on digital enterprises, the author presents empirical
research carried out over 4 years in collaboration with the
Startup Poland Foundation, and provides a developed universal
definition of a startup. This book highlights the necessity of a
clear definition, in order for startups to be treated as a
permanent economic phenomenon, rather than a temporary whim.
Addressing the crucial need for an effective startup management
methodology... more...

Description:
This book focuses on the two-phase flow problems relevant in the
automotive and power generation sectors. It includes fundamental
studies on liquid–gas two-phase interactions, nucleate and film
boiling, condensation, cavitation, suspension flows as well as
the latest developments in the field of two-phase problems
pertaining to power generation systems. It also discusses the
latest analytical, numerical and experimental techniques for
investigating the role of two-phase flows in performance analysis
of devices like combustion engines, gas turbines, nuclear
reactors and fuel cells. The wide scope of applications of this... more...

Description: This book provides valuable new insights into preventive measures
for chronic arsenic poisoning, exploring the various causes,
metabolism and toxicity, preventive drugs, functional foods and
various methods for removing arsenic from contaminated water. The
mechanisms of chronic arsenic poisoning vary between countries and
regions, and the pathological difference, though reported on, is
still only poorly understood. As large-scale chronic arsenic
poisoning is concentrated in Asia, the contributions in this book
were written by pioneers from Asia. Further, the management of
removed arsenic has not yet become standardized, and this volume
will serve... more...

Description:
This book reviews the most important issues related to acetabular
revision hip surgery and assesses the different management
procedures that are currently used in light of the challenging
major defects. Since the 1970s there has been a continual rise in
the annual number of total hip arthroplasty (THA) procedures
which has increased the demand for revision surgeries. Most
revisions operations of the hip are the result of acetabular
problems and early failures are usually related to acetabular
bone defects in complex primary THAs. &nbsp;Long-term failures
are mostly due to wear debris and osteolysis-related problems and
both... more...

Description: This book provides an extensive guide for exercise and health
professionals, students, scientists, sport coaches, athletes of
various sports and those with a general interest in concurrent
aerobic and strength training. Following a brief historical
overview of the past decades of research on concurrent training, in
section 1 the epigenetic as well as physiological and neuromuscular
differences of aerobic and strength training are discussed.
Thereafter, section 2 aims at providing an up-to-date analysis of
existing explanations for the interference phenomenon, while in
section 3 the training-methodological difficulties of combined
aerobic and... more...

Description:
This book is a practical guide to the management of patients with
breast malignancies. It serves as a&nbsp;quick reference book
that gives the most up-to-date routine practical management
strategies of breast cancer. Written and edited by leading
experts, this handbook focuses on the application of conventional
and novel treatment strategies to the care of patients with
malignant breast disease and all stages of breast cancer. The
chapters provide evidence-based treatment strategies for all
patient subsets. Surgical, radiation, and medical treatment
options are all discussed for each stage of breast cancer. It
also includes... more...

Description:
This book simplifies the complex subject of strabismus for
postgraduate students of ophthalmology. It clarifies the basic
concepts and includes clinical tips, illustrations, flow charts
as well as multiple-choice questions to aid understanding. It
also provides essential information that students require for
examinations.
Further, it encourages ophthalmologists who do not usually deal
with strabismus patients to identify and manage uncomplicated
cases. It discusses various management options, including the
guidelines for refraction and spectacle prescription, which are
often neglected. Separate... more...

Description: This book combines valid physiology and treatment strategies with
the institutional experience of one of the leading German pediatric
heart centers. It is intended as a pragmatic guide, focusing on
daily practice and bedside medicine: straightforward, easy to
implement, and results-oriented. It offers readers a profound
understanding of intensive care, with a specific focus on organ
systems, their interactions, and the effect of life support
technologies, pursuing a comprehensive approach to congenital heart
defects and therapies, including pitfalls and solutions. The target
group is extended towards pediatric cardiologists and
anesthesiologists by... more...

Description:
This text provides a concise yet comprehensive overview of
anemia in the young and old. The first section of the volume
features age-specific diagnostic approaches to anemia, from the
perinatal period to the elderly, with a particular emphasis on
age-specific epidemiology, differential diagnosis, and testing.
The second section focuses on specific anemia disorders,
including inherited bone marrow failure syndromes, iron
deficiency anemia, renal anemia, pure red cell anemia, and
anemia of inflammation and chronic disease. Each chapter in
this section revolves around a specific syndrome or group of... more...

Description: The acquired immunodeficiency syndrome (AIDS) and the AIDS­ related
complex (ARC) are caused by the human immunodeficien­ cy virus
(HIV-I), previously known as human T-celllymphotropic virus type
III (HTLV-III) or lymphadenopathy-associated virus (LA V). It seems
that additional retroviruses (HIV-II and perhaps 1 3 others) are
able to cause variants of AIDS or ARC. - Patients infected wi~h the
virus may (but do not necessarily) de­ velop a wide range of
clinical symptoms that are not directly relat­ ed to the virus
itself, but are secondary to the devastating effects of the viral
infection on' the human immune system. The virus thus renders... more...

Description: The lifestyles and socio-economic status that are prevalent in
regions of the world with limited resources form the background for
the unique features of neoplastic diseases in these areas, where
the majority of the world population lives. The predominance of the
world’s retroviral burden of&nbsp; in these areas further compounds
the nature and challenges of the cancer there. Much of the
international cancer literature covers the nature and challenges of
the disease as seen in high-income regions of the world, thereby
giving a skewed view of the global cancer challenges. As the low-
and middle-income regions of the world transition from... more...

Description: The lifestyles and socio-economic status that are prevalent in
regions of the world with limited resources form the background for
the unique features of neoplastic diseases in these areas, where
the majority of the world population lives. The predominance of the
world’s retroviral burden of&nbsp; in these areas further compounds
the nature and challenges of the cancer there. Much of the
international cancer literature covers the nature and challenges of
the disease as seen in high-income regions of the world, thereby
giving a skewed view of the global cancer challenges. As the low-
and middle-income regions of the world transition from... more...

Description: The lifestyles and socio-economic status that are prevalent in
regions of the world with limited resources form the background for
the unique features of neoplastic diseases in these areas, where
the majority of the world population lives. The predominance of the
world’s retroviral burden of&nbsp; in these areas further compounds
the nature and challenges of the cancer there. Much of the
international cancer literature covers the nature and challenges of
the disease as seen in high-income regions of the world, thereby
giving a skewed view of the global cancer challenges. As the low-
and middle-income regions of the world transition from... more...

Description:
This volume provides a comprehensive, state-of-the-art
overview on interventional endoscopic ultrasound (EUS). Each
chapter covers a single procedure or related group of
procedures, features a detailed literature evaluation and
tips on these cutting edge endoscopic techniques, and is
accompanied by a comprehensive endoscopic video and
illustrative endoscopic and ultrasonographic images. The text
also reviews adverse events related to interventional EUS,
both how to avoid them and how to manage them when they
arise.
&nbsp;
Written by to endoscopic... more...

Description:
The second edition of this well-received book provides a
comprehensive and up-to-date description of the diagnosis and
management of dysphagia, including oral, pharyngeal, and
esophageal dysfunction. All aspects of dysphagia are covered,
with detailed consideration of anatomy, physiology, and
pathology. In addition to a variety of benign and malignant
disease entities, signs and symptoms, and treatment approaches,
many other relevant topics are addressed, including endoscopy,
manometry, malnutrition, dehydration, oral care, dementia,
ethics, and the social and psychologic impacts of dysphagia.
Specific aspects of importance... more...

Description:
This open access book relates to the III Annual Conference hosted
by The Ministry of Education and Science of the Russian
Federation in December 2016. This event has summarized, analyzed
and&nbsp;discussed the interim results, academic outputs and
scientific achievements of the&nbsp;Russian Federal Targeted
Programme “Research and Development in Priority Areas of
Development&nbsp;of the Russian Scientific and
Technological&nbsp; Complex for 2014–2020.” It&nbsp;contains 75
selected papers from 6 areas considered priority by the Federal
Targeted Programme: computer science, ecology &amp; environment
sciences; energy and... more...

Description:
This volume identifies gaps in the assessment, management, and
communication of food allergen risks. Chapters showcase best
practices in managing allergen risks at various stages of the
food chain, including during food manufacture/processing; during
food preparation in food service, retail food establishments, and
in the home; and at the point of consumption. The authors
highlight key legislative initiatives that are in various stages
of development and implementation at the federal, state and
community levels. Finally, the volume includes recommendations
for ways to build and strengthen education and outreach efforts
at the... more...

Description:
The book brings together the current knowledge and future
perspectives of the complex physiology and pathophysiology of
gut-liver interactions in health and disease. It provides readers
with a unique overview and access to knowledge that cannot be
obtained elsewhere.
The structure is logical and covers all aspect including the
normal physiology, changes in various liver diseases, technology,
sample collection and various interventions. Thus suitable for
general reading, lookup for specific questions or as a reference
book within the area.
The book allows the reader to access all the knowledge that has
been generated... more...

Description: This modern textbook guides the reader through the theory and
practice of the motion and attitude control of space vehicles. It
first presents the fundamental principles of spaceflight mechanics
and then addresses more complex concepts and applications of
perturbation theory, orbit determination and refinement, space
propulsion, orbital maneuvers, interplanetary trajectories,
gyroscope dynamics, attitude control, and rocket performance. Many
algorithms used in the modern practice of trajectory computation
are also provided. The numerical treatment of the equations of
motion, the related methods, and the tables needed to use them
receive particular... more...

Description: This book provides essential insights into the various
pathogeneses, diagnoses and therapies for patients with gastric
cancer. Special attention is given to trending topics: endoscopic
diagnosis, cancer screening and eradication of H. pylori as
prevention of the disease. A dedicated section focuses on risk
classification and cancer screening/diagnosis, and is intended for
practical use in clinical doctors’ day-to-day management of
patients. Since cancer screening and prevention is currently only
practiced in Japan, this book is intended to disseminate new
findings and serve as a point of departure for further research.
Abundant color... more...

Description:
This book offers a concise review and international perspective
on state-of-the art unicompartmental knee reconstruction
procedures. To apply less invasive procedures resulting in fewer
complications and shorter recoveries, it provides insights on
patient selection, equipment design, and surgical techniques.
Newer concepts such as the use of robotics and haptic surgery as
well as outpatient surgeries are natural extensions of these
surgeries. Long term outcomes along with complications and future
directions are discussed as well.
Partial Knee Arthroplasty presents an ideal resource for
the occasional partial knee... more...

Description:
This volume reviews the application of biochemical and molecular
pathologies, which are based on conventional pathomorphology,
toxicology, and DNA analysis technologies, not only to autopsies
but also to the field of clinical medicine in general.
The systematic and integrated use of biochemical,
immmunohistochemical, and molecular pathology, toxicology, DNA
analysis, and cell culture investigations reinforces the
pathophysiological diagnostic criteria in a forensic autopsy for
clinical diagnosis. The use of these technologies can help to
determine the cause and process of death and characterize the
functional... more...

Description: Quality reporting is a rapidly growing area. &nbsp;Each year, new
regulations in the US from the Council of Medicare and Medicaid
Services make quality reporting a larger factor in determining
reimbursement practices. Quality metrics are common parts of
European clinical practice. &nbsp;Value of care is a focus of all
payers, with specific interest directed at assessing the quality of
care provided by a given healthcare team. &nbsp;While there are
many publications in this space, no text has sought to provide an
overview of quality in spine care.
&nbsp;
Quality measurement and quality reporting are ever growing
aspects of the healthcare... more...

Description:
In this book, leading experts in cancer immunotherapy join forces
to provide a comprehensive guide that sets out the main
principles of oncoimmunology and examines the latest advances and
their implications for clinical practice, focusing in particular
on drugs with FDA/EMA approvals and breakthrough status. The aim
is to deliver a landmark educational tool that will serve as the
definitive reference for MD and PhD students while also meeting
the needs of established researchers and healthcare
professionals.
Immunotherapy-based approaches are now inducing long-lasting
clinical responses across multiple histological types... more...

Description: This book elucidates a number of new concepts on P-wave evaluation
and QRS depolarization properties, and reports on several
repolarization findings never covered in previous ECG books. The
content is primarily based on case reports, some of which are
compared in order to reveal their ostensibly small but significant
differences. The book addresses a significant and lingering gap in
ECG interpretation, which is the actual cause of many poor
decisions in the diagnostic and therapeutic contexts. Further, the
book has an interdisciplinary appeal, and will be of equal interest
to professionals and scholars with an interest in cardiology and
ECG... more...

Description:
This volume provides a concise yet comprehensive overview of
minimal residual disease (MRD) testing. The text reviews the
history of MRD testing, MRD testing for acute lymphoblastic
leukemia/lymphoma, molecular diagnostics for MRD analysis in
hematopoietic malignancies, the use of "difference from normal"
flow cytometry in monitoring AML response, ML-DS for measurable
residual disease detection, and advancements in next generation
sequencing for detecting MRD.&nbsp;
Written by experts in the field,&nbsp;Minimal Residual
Disease Testing: Current Innovations and Future
Directions&nbsp;is a... more...

Description:
This book offers an up-to-date review on the principles and
practice of multidimensional assessment and management of the
older individual, which represents the cornerstone of modern
clinical practice in the elderly. The early chapters cover the
main elements and scope of the comprehensive geriatric approach
and explain the pathways of care from screening and case finding
through to in-depth assessment and treatment planning. Subsequent
chapters review the evidence of how best to apply the
multidimensional assessment and management approach in defined
healthcare settings and within specific clinical areas, such as
cancer and... more...

Description: The lifestyles and socio-economic status that are prevalent in
regions of the world with limited resources form the background for
the unique features of neoplastic diseases in these areas, where
the majority of the world population lives. The predominance of the
world’s retroviral burden of&nbsp; in these areas further compounds
the nature and challenges of the cancer there. Much of the
international cancer literature covers the nature and challenges of
the disease as seen in high-income regions of the world, thereby
giving a skewed view of the global cancer challenges. As the low-
and middle-income regions of the world transition from... more...

Description:
This book aims to provide comprehensive pictures of airway
stenting technology in interventional radiology to clinical
practitioners. The highlight of this book is that design concept
and structure of stent are described in detail for readers to
choose suitable stents for different airway diseases.
The first part of the book introduces readers to airway
foundation on basic ideas of trachea anatomy, common symptoms and
imaging signs of respiratory system. The second part provides a
broad overview of clinical application of interventional
radiology in airway diseases, while the third part presents
detailed interventional... more...

Description: This special volume focuses on optimization and control of processes governed by partial differential equations. The contributors are mostly participants of the DFG-priority program 1253: Optimization with PDE-constraints which is active since 2006. The book is organized in sections which cover almost the entire spectrum of modern research in this emerging field. Indeed, even though the field of optimal control and optimization for PDE-constrained problems has undergone a dramatic increase of interest during the last four decades, a full theory for nonlinear problems is still lacking. The contributions of this volume, some of which have the... more...

Description: Renal cell carcinoma (RCC) is the most common primary malignancy of
the kidney, with an estimated 64,000 new cases diagnosed each year
in the United States. Worldwide, this figure approaches 270,000
annual incident cases. At the time of initial presentation, 80% of
patients with RCC will be diagnosed with a tumor localized the
kidney. The majority of these lesions will be small (i.e. ≤4 cm)
and potentially curable with either partial or radical nephrectomy.
In recent decades, the rate of incidentally detected small renal
tumors has risen substantially due the increasing use of
cross-sectional imaging performed across the field of medicine.
This... more...

Description:
This book aimed to provide the most thorough knowledge of ocular
anatomy related to trauma and standard ocular examinations to
clinical practitioners, such as the nurses, medical students,
residents, fellows and even ophthalmologists, to help them making
the most appropriate decision on the management of patients who
have suffered from such ocular conditions. A thorough
understanding of the anatomy of the eyeball and the traumatic
characteristics of each structure of the eyeball are a
prerequisite for proper interpretation of long-term outcomes of
mechanical eye injuries.
The first part provides the audiences general... more...

Description:
This work presents a clear approach for the reconstruction of
head and neck cancer excision defects. Starting with a brief
historical account of head and neck reconstruction, the
principles of resection and reconstruction of head and neck
cancer, the book then provides a detailed overview of head and
neck reconstruction based on head and neck subsites; various
reconstruction techniques; best approaches; and the challenges
faced in reconstruction and how to overcome them. Lastly, it
discusses future directions in head and neck
reconstruction.

Description:
This book offers complete coverage of classic (one-dimensional)
NMR as well as up-to-date coverage of two-dimensional NMR and
other modern methods. This book focuses on all aspects of NMR
including classic methods, modern techniques, practical advice
for execution of the NMR experiment, theory, and more. For
practicing NMR spectroscopists who want a better understanding of
their subject, professors who want a wider knowledge of NMR,
preparative (synthetic) organic chemists in industry who want to
have more information about how to prove the structures of the
compounds they make, and analytical chemists in industry who... more...

Description:
This book serves as a comprehensive resource for researchers and
regulatory bodies working to establish sound evidence bases
through research for the care of children and families affected
by abuse. Issues such as consent, anonymous research, and how to
interface with the legal system in terms of disclosure and
sharing of results are discussed in depth. Ethical Issues in
Child Abuse Research also provides insights into questions of
ethics in animal research, perpetrator and retrospective
research, and balances the necessity of collecting this valuable
information while protecting vulnerable populations, and
respecting their... more...

Description:
This book provides an overview of the most up-to-date research on
diabetic nephropathy and the current understanding of its
pathogenesis, clinical features and socio-economic developments.
Written by leading experts in the field, it provides
a&nbsp;comprehensive synthesis of clinical and pathophysiological
aspects&nbsp;from a mechanism-based point of view, and reviews
evidence-based treatment modalities for the prevention and
management of diabetic nephropathy. In addition, closely related
areas such as diabesity, diabetic eye disease and
macrovascular involvement in diabetes are addressed.
Diabetic Nephropathy&nbsp;will be... more...

Description: NMR has made important contributions to our understanding of
structure–property relationships in polymers. This book provides an
up-to-date and comprehensive overview of the fundamentals of NMR,
with applications of multidimensional NMR and the new solution and
solid-state methods in polymer science. NMR of Polymers is
written by leading authorities for graduate students and
professionals in academia and industry.
Key Features
* Provides comprehensive overview of NMR in Polymer Science
* Covers multidimensional NMR
* Includes new solution and solid state methods
* Addresses chain conformation and dynamics

Description: This book focuses on the theoretical problems associated with molecular diversity as it is being applied in the pharmaceutical industry. Therefore, this book deals with algorithms that are involved in understanding chemical space and selection of diverse sets of structures. The algorithms also deal with the problem of focused diversity where chemical libraries are being created within a structured physical volume. Diversity is necessarily connected to combinational chemistry, although this book is limited to the application of diversity methods to combinational chemistry and does not deal with synthetic methods. It is this focus on... more...

Description:
This book focuses on traumatic birth injuries, predominantly of
the skull and brain, as well as hemorrhagic and ischemic
disorders of cerebral circulation in fetuses and newborns,
providing information on each condition’s classification,
incidence, etiology and pathogenesis, pathomorphology, clinic,
diagnostics, prognosis, and complications. It discusses the
configuration (molding) of the head, venous congestion,
displacements of cranial bones, ruptures of the cerebellar
tentorium during labor, and the compression of the skull and
brain damage caused by obstetric operations and asynclitic
insertion of the head, while also... more...

Description: This is a handbook for policy makers and environmental managers in
water authorities and engineering companies engaged in water
quality programmes, especially in developing countries. It is also
suitable for use as a textbook or as training material for water
quality management courses. It is a companion volume to Water
Quality Assessment and Water Quality Monitoring.

Description: Convolution and Equidistribution explores an important aspect of number theory--the theory of exponential sums over finite fields and their Mellin transforms--from a new, categorical point of view. The book presents fundamentally important results and a plethora of examples, opening up new directions in the subject. The finite-field Mellin transform (of a function on the multiplicative group of a finite field) is defined by summing that function against variable multiplicative characters. The basic question considered in the book is how the values of the Mellin transform are distributed (in a probabilistic sense), in cases where the input function... more...

Description: This book presents the latest developments in biometrics
technologies and reports on new approaches, methods, findings, and
technologies developed or being developed by the research community
and the industry. The book focuses on introducing fundamental
principles and concepts of key enabling technologies for biometric
systems applied for both physical and cyber security. The authors
disseminate recent research and developing efforts in this area,
investigate related trends and challenges, and present case studies
and examples such as fingerprint, face, iris, retina, keystroke
dynamics, and voice applications . The authors also investigate the... more...

Description: This is an extensive synthesis of recent work in the study of endomorphism rings and their modules, bringing together direct sum decompositions of modules, the class number of an algebraic number field, point set topological spaces, and classical noncommutative localization. The main idea behind the book is to study modules G over a ring R via their endomorphism ring EndR(G). The author discusses a wealth of results that classify G and EndR(G) via numerous properties, and in particular results from point set topology are used to provide a complete characterization of the direct sum decomposition properties of G. For graduate students this is a... more...

Description:
This updated and expanded second edition covers all of the
diagnostic areas where FNAC is used today. Each chapter follows a
similar, practical format: diagnostic criteria with an emphasis
of differential diagnoses; diagnostic problems and pitfalls; and
relevant findings of ancillary methods. Authoritative discussions
will reflect accepted international viewpoints. The interaction
of the cytologist or cytopathologist with other specialists
(radiologists, oncologists and surgeons) is emphasized and
illustrated throughout.
With contributions from experts in the field internationally and
many new colour images Atlas of Fine... more...

Description:
This book focuses on Barrett’s Esophagus (BE), a clinical
condition that must be evaluated in all patients affected by
chronic GERD, and with an important link to esophageal cancer.
Divided into four sections (morphological background,
epidemiology and natural history, diagnosis, and treatments),
this handy volume provides the latest indications regarding
endoscopic approaches (first level and advanced endoscopy),
pathological studies (pathology and molecular biology), and
state-of-the-art therapeutic options (medical, endoscopic, and
surgical) for BE. As such, it offers a valuable reference guide
for all professionals... more...

Description:
This SpringerBrief introduces the basics of &nbsp;wireless
powered communication&nbsp;networks (WPCNs). In particular, the
background and concept of WPCNs are briefly discussed. Moreover,
this brief&nbsp;provides an extensive study of the recent
developments in this area from&nbsp;an optimization perspective.
Wireless powered&nbsp;communication network (WPCN) is a new
network paradigm for IoT, where wireless devices (WDs) are
powered by radio frequency (RF) based wireless power
transfer&nbsp;(WPT) to eliminate the need for recharging or
replacing the batteries&nbsp;manually and to prolong their
lifetime.In this context, the... more...