ENGLISH ABSTRACT: Type 2 diabetes is a major source of morbidity and mortality worldwide, accounting for approximately 90% of the 415 million individuals who have Diabetes mellitus globally. The prevalence of T2D in South ...

ENGLISH ABSTRACT: Tuberculosis remains a major worldwide health threat. Among those infected there is risk of
Mycobacterium tuberculosis, the causative agent of tuberculosis, developing into an asymptomatic
dormant state. ...

ENGLISH ABSTRACT: Antibiotic resistance in Mycobacterium tuberculosis is a worldwide problem as it drastically affects patient treatment outcome. The development of drug resistance is due to the acquisition of mutations ...

ENGLISH ABSTRACT: Anxiety disorders are a range of complex disorders characterised by abnormal anxiety in the
absence of anxiety-provoking stimuli. The aetiology of anxiety disorders is attributed to
interaction between ...

ENGLISH ABSTRACT: Cattle and African buffaloes are major maintenance hosts of Mycobacterium bovis in South Africa and therefore serve as a potential source of infection for other animals and humans. Mycobacterium bovis is ...

Background
There is a high co-prevalence between type 2 diabetes (DM2) and other infectious diseases. This is particularly problematic with the rise in co-prevalence between DM2 and Tuberculosis (TB). However, the underlying ...

ENGLISH ABSTRACT: The pathogenicity of Mycobacterium tuberculosis (M.tb) is determined by its ability to survive within host macrophages. The mammalian autophagy pathway is now recognised as a major contributor to disease ...

ENGLISH SUMMARY: Anxiety disorders are among the most prevalent psychiatric disorders among both adults and adolescents. Comorbidity with other psychiatric disorders, including other anxiety disorders, is common and it is ...

ENGLISH SUMMARY: The host immune response to tuberculosis is extremely complex, and in order to fully elucidate this, one has to thoroughly study the host response by considering all immune cells and phases of infection. ...

ENGLISH SUMMARY: Tuberculous meningitis (TBM) is a type of extrapulmonary tuberculosis (TB) which leads to inflammation of the meninges through small lesions called Rich foci. TBM represents 1% of total TB disease, with ...

ENGLISH SUMMARY: Parkinson’s disease (PD) is the most common neurodegenerative movement disorder and is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta. Dopaminergic neuronal loss ...

ENGLISH SUMMARY: BACKGROUND: There is an urgent need for new tools for the rapid diagnosis of tuberculosis (TB) disease and monitoring of the response to treatment. OBJECTIVES:
To investigate the usefulness of host markers ...

ENGLISH ABSTRACT : Tuberculosis has continued to be a global health concern and warrants an increased understanding of its causative agent Mycobacterium tuberculosis (M. tuberculosis) in terms of its evolution, virulence ...

ENGLISH ABSTRACT: MicroRNAs (miRNAs) are small non-coding RNAs that play a fundamental role in cellular function by regulating messenger RNA gene expression. Alterations in miRNA expression are implicated in metabolic ...

ENGLISH ABSTRACT : Mycobacterium tuberculosis remains one of the world’s deadliest pathogens, and
although decades of research have been dedicated to the discovery and development of
anti-tuberculosis agents and vaccines, ...

ENGLISH ABSTRACT : The therapeutic depletion therapy of B cells in humans have led to the discovery that B cells have the potential
to function within immunity in a non-humoral fashion. Although this attribute wasn’t ...

ENGLISH ABSTRACT : Bovine tuberculosis (bTB), caused by Mycobacterium bovis, is a chronic infectious disease known to occur in free-ranging mammals, captive wildlife, and livestock. M. bovis forms part of the Mycobacterium ...