The pass is particularly well known for its frequent inclusion in the Paris–Nice road cycling stage race, where it has often formed the final decisive stage of the race.[2] From 1969 to 1995 the race finished with a time trial up the Col d'Èze, except in 1977 when landslides had blocked the road.[3] The Col d'Èze is a 9 km climb, starting from Nice and climbing to 507 m altitude. It is named after the village of Èze, part of the municipality of Nice. Sean Kelly won the Col d'Èze time trial five times in his seven-year dominance.

In 1996, the finish was moved back to the Promenade des Anglais because of the low number of spectators on Col d'Eze and to take advantage of funding from the city of Nice. From 1998 to 2011, the final stage was a road race – usually on a hilly terrain with the climbs of the Col d'Èze and La Turbie - starting and ending in Nice. In recent years the race often returns to a final Col d'Eze time trial stage. Bradley Wiggins set a new climbing record in 2012 of 19' 12" on his way to overall victory.[4]