We
introduce a novel minimally constrained myocardial perfusion analysis
technique. The technique has been implemented on dynamic contrast enhanced
magnetic resonance images, obtained from 10 patients with hypertrophic
cardiomyopathy. Regional myocardial perfusion estimates were directly
compared to both the Fermi perfusion model and a 2 compartment perfusion
model. The results indicate that there is discrepancy between Fermi and 2
compartment models during stress exams. However our technique correlates well
with the Fermi model during both stress and rest exams.