Drug
and Dietary Supplement Profiles

A comprehensive review of the safety and effectiveness of this drug. If the drug
is not a Do Not Use product, information on adverse effects, drug interactions
and how to use the medication are included.

Search results below include drug profiles where your selected drug is a secondary subject of discussion

Muscle Injury From Use of Simvastatin (ZOCOR) with Amiodarone (CORDARONE)
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(November 2008)
Despite the dangers of this combination--risk of severe muscle injury, rhabdomyolysis, which can lead to kidney failure or death--many clinicians continue to prescribe them together and cases of life-threatening adverse reactions from continue to be reported to the FDA. Patients taking simvastatin at a dose greater than 20 milligrams a day in combination with amiodarone should let their physician know that this combination puts them at high risk of muscle injury. There are other statins that do not appear to interact with amiodarone that are discussed.

Drug Interactions: Warfarin (COUMADIN)
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(December 2007)
This article explains how to understand the International Normalized Ratio (INR), a test applied to a sample of a patient’s blood to determine how “thin” it is when you are using the blood thinner COUMADIN (warfarin). In addition, the article lists more than 50 drugs or dietary supplements that can interact harmfully with COUMADIN to cause the blood to be too thin (abnormal bleeding) or not thin enough which could result in lessening the effect of COUMADIN in stopping blood clot formation.