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Factual error: Jeff, being a medical student doesn't really seem to know how to make sure infection doesn't occur. In the scenes where he is cutting out parts of plant from Stacy's body he pours alcohol on her body before cutting it. This is totally useless as he doesn't put alcohol on his hands, the knife or inside the open wound after he cuts it. Infection as almost certain to happen because of this. This is practically impossible to not know by a medical student.

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Jeff: People come from all over the world just to see these ruins, especially one that's not on the map. I'm not taking you to some tourist trap, honey. Don't you want to have some experience or something to shoot other than the beach, the pool, the beach, the pool?Amy: Well, you're already dressed, so you might as well go without me.Jeff: Hey, but I don't want to go without you.

When Amy says that she lost her earring, she's wearing shades. The shot cuts to Stacy and then back to Amy, who is now wearing spectacles without having had enough time to change her glasses off screen.

Throughout the film, the five characters on the Mayan structure walk around in thin clothing day and night. In reality, it was quite chilly; the director and crew wore jackets to shield them from the cold.