Here are five high points and low points in Chuck Pagano's tenure as Indianapolis Colts coach. He was fired Sunday after going 53-43 in regular-season play over six seasons, with three playoff appearances, including one AFC Championship game berth. This year's team finished 4-12.

2012 VICTORY OVER GREEN BAY

► During the bye week before this game, first-year coach Chuck Pagano announced that he had a rare form of leukemia and would be out indefinitely.

► The Colts, picked to be the worst in the NFL at the start of the season, were 1-2.

► They trailed 21-3.

This was the first true glimpse of what this team could accomplish. Under interim coach Bruce Arians, Andrew Luck put the Colts ahead 22-21. Then, after Green Bay scored with 4:30 to play to re-take the lead, Luck hit Reggie Wayne — who had 13 catches for 212 yards wearing orange gloves in honor of Pagano — for a 4-yard touchdown with 35 seconds left for the 30-27 victory.

This is what IndyStar columnist Bob Kravitz wrote:

"In my 40 years in this business, I've never been prouder of a team and how they battled back," Indianapolis Colts owner Jim Irsay told me after he and General Manager Ryan Grigson presented coach Chuck Pagano with the game ball early Sunday night at the IU Health Simon Cancer Center. "I've been in a lot of winning locker rooms, Super Bowl locker rooms, but I've never had an experience like this. People talk about money, what the team is worth, those kinds of things, but this was priceless. Absolutely priceless.

"We walked in, he (Pagano) got up, we all embraced and shed some tears, and Chuck said, 'You know, I don't feel so sick right now.'"

Luck is known for his game-winning, fourth-quarter drives, posting 18 since he was drafted.

The Colts also posted a strong record in games decided by eight points or fewer during Pagano's tenure: 35-19, a .648 winning percentage. The record was 19-4 in the first three years of Pagano's tenure.

Pagano and Grigson inherited a team coming off a 2-14 season with a horrific salary cap situation ... and went 11-5. Here is how Kravitz described Pagano's return from his battle with cancer to win the season finale and reach the playoffs:

This is why we pay attention to sports. Because they have the power to inspire. Because they are real. Because they have the ability to move us in the most remarkable ways.

Want to feel good this morning? Check out the post-game video on Colts.com. There were Pagano's players, dancing, and there was Pagano dancing, although he needs to work on those dance moves before it comes time for his daughters' weddings. At one point, he turned to team owner Jim Irsay, hugged, and then the pair danced together.

A special scene. A special football team.

The Colts posted 11-5 records again in 2013 and '14, using a historic comeback to defeat Kansas City in 2013 to advance to the second round (see below), then reaching the 2014 AFC Championship game (more on that later, too).

Colts owner Jim Irsay had taken to comparing the start of the Pagano-Grigson era to that of Polian-Manning. Even given the disappointment of the past two seasons, Pagano-Grigson were 49-31 in their five years with a 3-3 record in the playoffs. The Polian-Manning Colts were 42-38 with an 0-3 record in the postseason.

Yes, you can dismiss that comparison by noting the Polian-Manning teams were on the rise, while the Pagano-Grigson teams stagnated.

But you can't dismiss the first three seasons.

COMEBACK VERSUS KANSAS CITY

Colts quarterback Andrew Luck scores in the fourth quarter after recovering a fumble and diving into the end zone against the Kansas City Chiefs.(Photo11: Mike Fender/IndyStar)

The Colts trailed Kansas City 38-10 in the third quarter on Jan. 4, 2014. They came back to win 45-44.

Kravitz:

This is how Andrew Luck starts his legend. Years from now, you'll always know where you were, how you were feeling the moment Luck put the Indianapolis Colts on his broad shoulders and led them back from a 38-10 deficit and willed the Colts to a 45-44 wild card victory over the star-crossed Kansas City Chiefs.

John Elway had The Drive.

Luck has The Comeback.

And to think, it was just his first-ever postseason win. What's a guy do for an encore?

This is the foundation upon which legends are formed. This is why Luck has every chance to someday be remembered as one of the greatest quarterbacks ever to play this game. Not simply because of his arm or his legs, but because of his force of will.

In the second half, Luck was 17-of-22 for 314 yards — a cool 14.3 yards per attempt — with three touchdowns, plus 22 rushing yards, 5 returning a Donald Brown fumble for a touchdown.

VICTORIES OVER DENVER ... AND PEYTON MANNING

Denver Broncos quarterback Peyton Manning is hit from behind by former teammate Robert Mathis.(Photo11: Robert Scheer/IndyStar)

It's certainly fair to question the Colts' success in big games during the Pagano (and, yes, Luck) era, but perhaps the two biggest victories came against an old friend.

When the Colts hosted Peyton Manning for the first time on Oct. 20, 2013, doubts had been cast on just how quickly they would establish themselves. The Colts were coming off a surprising loss to San Diego that dropped them to 4-2; Denver was coming in at 6-0 with Manning at the height of his abilities. A 4-3 record heading into the bye week was a distinct possibility.

But Robert Mathis delivered a strip-sack of Manning that resulted in a safety to cut the Broncos' lead to 14-12. The Colts took the lead after the ensuing free kick and didn't trail again. Luck (228 passing yards, four total touchdowns) out-performed Manning (386 yards, three touchdowns, one interception, one fumble).

Kravitz captured the moment:

It was Peyton Week.

But it was a Colts Sunday night.

You may exhale now: Indianapolis Colts 39, Manning's Broncos 33.

After a week of hype and harsh words, and a night of adulation and special sentiments during which Peyton Manning was the focus of the football world's attention, it turned out the game had less to do with No. 18 and more to do with the Colts' Other Guys.

It had everything to do with the Colts defense, and especially Robert Mathis, who has been waiting a decade to blind-side and strip-sack Manning. Mathis is having a Defensive Player of the Year type of season.

The teams were in similar situations when they met on Jan. 11, 2015, the Colts an underdog in Denver in the Divisional round of the playoffs. Denver was 12-4 and coming off a bye. Manning again took an early lead — 7-0 — but the Colts quickly established themselves as the better team on defense. The Colts advanced to the AFC Championship Game by holding Manning to 26-of-46 for 211 yards with one touchdown and a fumble.

By beating the Broncos in Denver, and by doing it the way they did it, the Colts have shut up every critic, answered every question, earned every benefit of the doubt. And for weeks there have been doubts. Well-deserved doubts. Which doubts?

It doesn't matter. Not after this game, when the Colts made the Broncos look so bad that the crowd turned on the home team, booing Peyton Manning for missed passes and booing the Denver coaches for play calls before leaving the stadium with several minutes left and the Broncos in theory still having a chance.

Not that theories mattered much Sunday. Because the theory was, the Colts couldn't win this game.

"As far as the critics go and the pundits," said Colts coach Chuck Pagano, "I don't think anybody thought we could come in here and get this done."

TWO WINS TO FINISH 2015

It was an extraordinary, perhaps unprecedented, swing of public opinion given the facts.

In a three-week stretch, the Colts were blown out by Pittsburgh (45-11), embarrassed by Jacksonville (51-17) then lost a must-win game to Houston and backup quarterback Brandon Weeden, who had lost 11 consecutive games as a starter, in Lucas Oil Stadium.

Yes, Luck was out for the season but the fans, seemingly, had had enough of Chuck Pagano.

All true, and not good enough. Not for a franchise with the best young quarterback in the NFL.

Blowout losses have been a recurring theme in the Pagano era with 10 by more than 26 points.

FAKE PUNT

With Indianapolis Colts wide receiver Griff Whalen (17) lining up on the ball, and free safety Colt Anderson (32) preparing to take the hike, a bizarre play during second half action befuddled many on and off the field of an NFL football game Sunday, Oct. 18, 2015, at Lucas Oil Stadium.(Photo11: Matt_Kryger / The_Star)

Colt Anderson lined up under Griff Whalen on fourth-and-3 from the Colts' 37-yard line with the Patriots leading 27-21 and 1:14 remaining in the third quarter. With three Patriots lined up over him, Whalen snapped the ball and Anderson was tackled for a 3-yard loss.

The Patriots scored on the ensuing possession to take a 34-21 lead in an eventual 34-27 victory on Oct. 18, 2015.

... Pagano never came out and said what he should have said, what we now know, that Whalen was the wrong guy in the wrong place at the wrong time. What Pagano said was this: The Colts worked on that play all week in practice.

"It wasn't desperation," he said after the game. "It was stuff that was practiced."

... just not by Griff Whalen.

Did Pagano forget that part?

The snapper all week in practice on that awful play, a play that will live forever in infamy — right up there with the Mark Sanchez butt fumble — was Clayton Geathers.

One of the recent hallmarks of the Indianapolis Colts was its traditional dominance in the AFC South. The Colts kept that tradition alive against the Houston Texans, Tennessee Titans and Jacksonville Jaguars early in Pagano's tenure, but the Colts have become the division doormat.

Here is the Colts' record against the AFC South each year of Pagano's tenure.

History has been completely turned on its head. The latest example? Sunday’s 30-10 Jaguars win over the Colts, a defeat that dropped Indianapolis to 3-9 and ensured the team its first losing season under Pagano.

This game, which comes after a 27-0 loss to Jacksonville in October, also begs an important and necessary question: Are the Jaguars really that much more dominant that the Colts right now?

Pagano, nearing the end of his sixth, and possibly final, season as Indianapolis’ coach, answered succinctly: “They were today.”

Except, the Jaguars’ superiority over the Colts extends well beyond Sunday. It’s also a mortifying reminder of the Colts’ current status in the AFC South – at the bottom looking up.

Jacksonville has now won four of its past five meetings with the Colts. They no longer are the Colts’ little brothers.

There's no question differences of opinion between Pagano and Grigson have affected the locker room. From Colts Insider Stephen Holder:

Coach Chuck Pagano and his staff are being directed to follow lineup decisions — usually the coaches' prerogative — made by the front office, something numerous NFL sources confirmed. This has been a recurring source of irritation for Pagano and his coaches. During the past several weeks, and even dating to last season, there have been instances in which, sources said, players approached Pagano or his assistants with suggestions or requests, only to be told they could not act on the ideas because of forces beyond their control.

Another concern noted by players is the continued speculation about the future of Pagano, who does not have a contract beyond 2015 and was involved in an unproductive contract negotiation with the club during the offseason. Pagano is still seen as being at risk of firing if results don't improve — the Colts are a disappointing 3-5 halfway through the season — though the move to oust offensive coordinator Pep Hamilton this week might buy Pagano some time.

There was much less discussion about the relationship between Pagano and Grigson in 2016, but it almost certainly had a negative effect on the team's performance during their tenure.

The Colts let Grigson go after the 2016 season, and new General Manager Chris Ballard kept Pagano.

"We've changed our model a little bit, because we wanted more than one of these," Irsay said, flicking up his right hand to show his Super Bowl XLI championship ring. "(Tom) Brady never had consistent numbers, but he has three of these. Pittsburgh had two, the Giants had two, Baltimore had two and we had one. That leaves you frustrated.

"You make the playoffs 11 times, and you're out in the first round seven out of 11 times. You love to have the Star Wars numbers from Peyton and Marvin (Harrison) and Reggie (Wayne). Mostly, you love this."

Irsay demanded Grigson and Pagano "build a well-rounded team, with the offense supported by outstanding special teams and a dependable defense."

Pagano was the coordinator of a Baltimore Ravens defense that ranked third in the NFL in yards and points allowed the year before he was hired.

It never transferred to the Colts.

Over the six-year Pagano era, the Colts finished better than 19th in points allowed (2013) and yards (2014) once, each. In 2016, they finished 30th in yards allowed per game.

Ballard overhauled the defense in his first few months in Indy. While the unit showed glimpses, particularly in stopping the run, there's still a long way to go. Entering Sunday's finale, the Colts were 27th against the run, 29th in total yards, 30th in passing yards and 31st in points allowed.