Continuous improvements in GC/MS and LC/MS have revealed a stunning array of pharmaceuticals and personal care products (PPCPs) in municipal wastewaters. What is known from global studies is that exposure to biologically active compounds, even at ng/L concentrations, can impact endocrine systems in nature and manifest as negative impacts like altered gene regulation, the presence of mixed reproductive tissues (intersex) and skewed sex ratios. Advancing Canadian Wastewater Assets (ACWA) is a research...

The analytical demands for detecting organic contaminants in water at low ng/L level have pushed the development of new methodologies using LC/TQ instrumentation. In this regard, and in the last few years, advances in sensitivity and selectivity have made this challenge possible. This webinar will focus on the use of the new 6470 LC-MS-MS from Agilent Technologies for the sub ng/L level detection of several pharmaceuticals and pesticides in surface waters. Examples of optimization of several source...

This webinar will present the concept and rationale for using a flipped classroom to teach analytical chemistry at university level. Along with presenting methods for how to create the flipped classroom, strategies on how to conduct the class time, and engage the students will be discussed.

Bone remains are one of the least characterized and most challenging matrices for forensic toxicological analysis. Before the forensic utility of the matrix may be fully realized, controlled experiments must be carried out. This presentation will highlight the value that UPLC-based approaches have brought to the drug analysis of bone samples. In addition, we will discuss the most recent findings in analytical developments using UPLC-QTof mass spectrometry, including: dramatic enhancements in sensitivity,...

Therapeutic proteins and peptides have emerged as one of the most important classes of new pharmaceuticals. Several drug candidates with potential performance-enhancing properties are currently in preclinical or clinical development. The current version of the WADA Prohibited List includes a variety of protein/peptide-based doping agents, some of which can be detected in biological samples by using immunological and mass spectrometry-based approaches.

This presentation outlines how some innovative Agilent products can help improve the performance and productivity of PerkinElmer ICP-OES and ICP-MS systems. We’ll illustrate the performance advantages by comparing performance indicators such as Limit of Detection, wash-out and memory effects, and sample to sample analysis times.

For high resolution MS to become accessible to the routine forensic toxicology laboratory, powerful and easy to use informatics is essential to process the large volume of data produced and successfully detect and identify components. This webinar will present on UPLC/QTof technology working in MS^E mode and the Waters UNIFI Scientific Information System for targeted, semi targeted and untargeted screening.