Nuvigil

DRUG DESCRIPTION

NUVIGIL (armodafinil) is a wakefulness-promoting agent
for oral administration. Armodafinil is the R-enantiomer of modafinil which is
a 1:1 mixture of the Rand S-enantiomers. The chemical name for armodafinil is
2-[(R)-(diphenylmethyl)sulfinyl]acetamide. The molecular formula is C15H15NO2S
and the molecular weight is 273.35.

The chemical structure is:

Armodafinil exists in multiple
crystalline forms. Form I, which is used in NUVIGIL, is the least soluble form
of armodafinil and is a white to off-white, crystalline powder that is slightly
soluble in water, sparingly soluble in acetone and soluble in methanol. At
least 90% of the armodafinil particles used in NUVIGIL have a diameter of less
than 200 microns.

What are the precautions when taking armodafinil (Nuvigil)?

Before taking armodafinil, tell your doctor or pharmacist if you are allergic to it; or to modafinil; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain heart problems (e.g., enlarged heart, mitral valve problem), history of problems (e.g., chest pain, irregular heartbeat) after taking stimulants such as amphetamines.