Health Encyclopedia

Erythema Nodosum

Definition

Erythema nodosum is the name given to extremely tender lumps on the legs and sometimes the arms. They are caused by inflammation of the fat beneath the skin. The bumps look like bruises. They change color in the same way, from pink to blue to brown.

Risk Factors

This condition is rare. It is more common in females and young adults aged 20-30 years old. Having any of the causes listed above will only slightly increase your risk of the disorder.

The risk factor for erythema nodosum is genetics.

Symptoms

Symptoms include:

Very tender, deep lumps, like bruises,

Usually located on your shins

May also appear on the forearms, trunk, neck, and head

Associated joint pain and fever and redness around the eyes

Diagnosis

You will be asked about your symptoms and medical history. A physical exam will be done, which may diagnose the problem based on a visual exam. You may be referred to a doctor that focuses on skin problems or infectious diseases.

Your bodily fluids and cells may be tested. This can be done with:

Blood and urine samples

Cultures

PPD skin test for tuberculosis

Biopsy of a lesion

Images may be taken of your bodily structures. This can be done with a
chest x-ray
and other imaging tests.

Treatment

If a cause can be identified, it will be treated. For the nodules themselves, pain relief is all that is needed. They tend to resolve on their own in about six weeks. They will not cause scarring. Treatment options include the following:

Pain Relief

Pain relief includes:

Bed rest and elevation of legs

Wet compresses

Aspirin, except in children

Nonsteroidal anti-inflammatory
drugs

Potassium iodide

Steroid Treatment

This may be necessary in severe cases.

Prevention

Some of the infectious causes can be avoided by practicing good hygiene, which includes:

Washing your hands often

Not sharing food, drinks, or utensils

Revision Information

This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.