parosteal osteosarcoma

pa·ros·te·al os·te·o·sar·co·ma

low-grade osteosarcoma arising on the surface of bone without involvement of the underlying marrow, usually occurring as a heavily ossified mass of the distal femur in women in the third and fourth decades of life.

parosteal osteosarcoma

An uncommon (4% of all osteosarcomas (OS)) indolent, painless OS of patients age 30 to 60, which arises in the metaphysis and is confined to the surface long bones (posterior distal femur, tibia, humerus; rarely hands or mandible). Parosteal OS lacks intramedullary involvement; it has mature lamellar bone, fibrous stroma, minimally increased cellularity, atypia and increased mitotic activity. Up to 70% arise on the surface of the distal femur. Recurrent parosteal OSs may dedifferentiate.

All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.