Macrophage Colony stimulating Factor (M-CSF) is produced by various cell types, including fibroblasts, microphages, and endothelial cells. M-CSF is involved in both the development and function of monocytes/microphages. Recombinant human M-CSF is a 36.8 kDa homodimeric protein containing two 159 amino acid polypeptide subunits.

Species

Human

Expression System

E. coli

Applications

Apuri, Blocking, ELISA, Functional Assay

Application Note

The ED50 as determined by the dose-dependent stimulation of the proliferation of murine M-NSF-60 cells is <5.0 ng/ml, corresponding to a specific activity of ≥2 x10^5 units/mg.