Stress hormone response to various anaesthetic techniques during thyreidectomy

Ewa Grycz, Andrzej Siemiątkowski

Anaesthesiol Intensive Ther 2012;44(1):4-7.

open access

Vol 44, No 1 (2012 Jan-Mar)

Original and clinical articles

Published online: 2012-03-30

Submitted: 2012-03-30

Accepted: 2012-03-30

Abstract

BACKGROUND: Thyroidectomy is among the most frequently performed procedures in endocrine surgery. The hormonal response to surgery and anaesthesia depends in part on the anaesthetic techniques used; therefore, we measured serum concentrations of TSH, fT4, and fT3 in patients scheduled for elective thyroidectomy under TIVA or VIMA.

METHODS: Seventy-eight adult patients, of both sexes, with non-toxic or hyperthyroid nodular goitre, were divided into groups with regard to the goitre type and the technique of anaesthesia used during thyroid surgery. Serum concentrations of TSH, fT4, and fT3, were measured and the surgical stress was estimated using the E-PASS scale.

RESULTS: In the groups examined, the mean serum concentrations of TSH remained unchanged during the period of observation. The initially high fT4 and fT3 concentrations gradually decreased, reaching their lowest level on the fourth day after surgery.

CONCUSIONS: Both VIMA and TIVA can be regarded as safe techniques of anaesthesia for thyroidectomy.

Abstract

BACKGROUND: Thyroidectomy is among the most frequently performed procedures in endocrine surgery. The hormonal response to surgery and anaesthesia depends in part on the anaesthetic techniques used; therefore, we measured serum concentrations of TSH, fT4, and fT3 in patients scheduled for elective thyroidectomy under TIVA or VIMA.

METHODS: Seventy-eight adult patients, of both sexes, with non-toxic or hyperthyroid nodular goitre, were divided into groups with regard to the goitre type and the technique of anaesthesia used during thyroid surgery. Serum concentrations of TSH, fT4, and fT3, were measured and the surgical stress was estimated using the E-PASS scale.

RESULTS: In the groups examined, the mean serum concentrations of TSH remained unchanged during the period of observation. The initially high fT4 and fT3 concentrations gradually decreased, reaching their lowest level on the fourth day after surgery.

CONCUSIONS: Both VIMA and TIVA can be regarded as safe techniques of anaesthesia for thyroidectomy.

Title

Journal

Issue

Pages

Published online

Bibliographic record

Anaesthesiol Intensive Ther 2012;44(1):4-7.

Keywords

hormones
thyroid
surgery
stress response
surgery
thyroid

Authors

Ewa Grycz
Andrzej Siemiątkowski

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