Through Diffusion Tensor Magnetic Resonance Imaging to Evaluate the Original Properties of Neural Pathways of Patients with Partial Seizures and Secondary Generalization by Individual Anatomic Reference Atlas

Supplementary Material

Sixteen patients having neocortical seizures with secondarily generalised convulsions and 16 age-matched normal subjects were imaged with high-resolution and diffusion tensor MRIs. Automated demarcation of supratentorial fibers was accomplished with personalized fiber-labeled atlases that were generated by transforming a template atlas to align with the individual brain images. Using the independent-samples t-test, the MD and FA values in the patient group were compared with those in the control group, as well as within the patient subgroups for the WM structures studied.

Supplementary Table 1: shows the comparisons between the patient and normal groups in terms of MD and FA in white matter integrity.

Supplementary Table 2: shows the number of voxels in the different fibers of the normal subjects.

Supplementary Table 3: shows the comparisons between the patients with two different onset age subgroups and normal groups in terms of MD and FA in white matter integrity.

Supplementary Table 4: shows the comparisons between the patients with drug-resistant and drug-effective subgroups and normal groups in terms of MD and FA in white matter integrity.