I gave up on MobileMe after losing data four times, spending many hours with Apple techies and just generally wasting my time. It would work after each round of lengthy fixes for some indeterminate time, usually a few days - I never figured out what stopped it each time. Maybe just a reboot or software update of any kind. It NEVER once worked while I was travelling and needed it. Goodbye, cloud computer for me.

The cloud hosting company goes belly up, and if your business depended on the cloud for it's computing, storage and development, your business is toast. And that's the benign scenario.

The nasty one is where the cloud company *knows* it has all of your data and infrastructure, and keeps jacking up the price while preventing you from migrating off due to proprietary applications, thus holding your business hostage.