Conan O'Brien is scheduled to be the final guest during Jay Leno's last "Tonight Show" on May 29. O'Brien, who has appeared with Leno on the program 16 times previously, will be taking over the coveted hosting duties beginning on June 1.

"I’m glad that it's going to be Conan," Leno said during a conference call with reporters Thursday. "It couldn’t go to a better person. I mean, he’s the guy and we’re friends and it’s a really smooth transition and I think it will be a lot of fun."

In addition, the week leading up to Leno's finale as host of "The Tonight Show with Jay Leno" will feature special guests and friends of the show including:

Monday, May 25: Mel Gibson will make his 21st appearance on the "The Tonight Show with Jay Leno" in his first sit-down interview since the announcement of his impending divorce.

Tuesday, May 26: Arnold Schwarzenegger made headlines when he made the now famous surprise announcement that he was running for governor of California during an appearance in 2003 and he will take to the couch again for his 25th appearance on the show.

Wednesday, May 27: Comedian Wanda Sykes, hot off her hosting duties at the White House Correspondents dinner, makes her 25th appearance with Leno.

Thursday, May 28: Billy Crystal boasts the title of the first guest ever to take a seat on "The Tonight Show with Jay Leno" when he appeared on the initial broadcast on May 25, 1992.

The musical guests for the week include Lyle Lovett who will appear on Monday, May 25 while Dwight Yoakam takes the stage on Tuesday, May 26. Sarah McLachlan, Prince and James Taylor will wrap up the week.

In addition to the special guests, video packages honoring 17 years of moments, gaffes and laughs on "The Tonight Show with Jay Leno" will premiere throughout the week.