College Football Week 12 Picks: Stanford Cardinal vs. USC Trojans

The underdog is 5-1 against the spread in the last six meetings between the Stanford Cardinal and USC Trojans, which is important to consider when making your college football Week 12 picks Saturday as the two teams face off at the Los Angeles Coliseum.

Sports bettors will find that the Trojans are four-point home underdogs in the NCAA football odds, with the betting total sitting at 46 in the market.

Let's take a closer look at this Pac-12 Conference matchup from a betting perspective, while offering up a prediction along the way.

Stanford Cardinal

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The Stanford Cardinal are 8-1 straight up and 5-4 against the spread through nine games of the 2013 campaign, as they come off a 26-20 victory over the Oregon Ducks as 10-point home underdogs last Thursday.

College football handicappers will find that the Cardinal have won 31 of their last 32 games played in California.

USC Trojans

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The USC Trojans have compiled a 4-1 straight-up and against-the-spread record since the firing of former head coach Lane Kiffin, which includes a 62-28 victory over the California Golden Bears as 18.5-point road favorites last Saturday.

College football handicappers will find that four of the last six meetings in this series have been decided by eight points or fewer, including the last three.