DRUG INTERACTION

NSAIDs such as ibuprofen, naproxen and calcium channel blockers (verapamil, nifedipine and diltiazem) taken with atenolol can severely lower blood pressure and reduce heart rate. Atenolol when administered with antiarrhythmic drugs (disopyramide, amiodarone), digoxin can cause severe lowering of heart rate. Use of other hypotensive with atenolol can cause excess lowering of blood pressure. Both digitalis glycosides and beta-blockers slow atrioventricular conduction and decrease heart rate. Concomitant use can decrease the heart rate (bradycardia). Administration with insulin or other oral anti-diabetics can impair sugar control. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

INTERACTIONS

Can I take Pertenol (25mg) during pregnancy?

Experiences of drug use and evidence from studies in pregnant women have shown risk to fetus. This drug may be used in pregnant women if benefit outweighs the risk. Patients should follow the advice of the doctor regarding its use.

Can I take Pertenol (25mg) while breastfeeding/lactation?

Possibly unsafe: Evidence from studies in breastfeeding women show that there is a definite risk of side effects to the breastfed infants. However, use of the drug in breastfeeding women is acceptable in spite of the risk to the infants, if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective. Patients should follow the advice of the doctor regarding its use.