Summary

In a paper of this nature it is difficult to epitomize the results any more briefly than has been done in the actual text. Only a few of the more important conclusions will be summarized.

1. The vena capitis median's is the primitive head vein. It is replaced by the vena capitis lateralis by different methods in the different groups.

2. The relations of the efferent pseudobranchial artery to the trabecula cranii differ in Selachians and the remaining Craniates.

This may be explained by vessel-looping in the Selachian or by the different relations of the polar cartilage.

3. The relations of the hyomandibular to the veins, hyomandibular muscle, and facial nerve in the different groups suggest that the hyomandibular (i) of Selachians is a true hyomandibular, (ii) of Teleosts and Amia a compound of an interarcual cartilage and a processus oticus hyomandibularis, the latter being a modified extra-hyal.

4. The schematic condition of the true hyomandibular with the processus oticus hyomandibularis is shadowed in Ceratodus, embryonic stages.

5. A certain number of constant relations exist, as set forth on p. 328.

Andreas Villunger and colleagues discuss the biology of the PIDDosome multiprotein complex and recent advances that link PIDDosome-dependent CASP2 activation to p53 activation in response to extra centrosomes.

Centrosomes and cilia are essential structures for many functions in development and disease. Sascha Werner, Ana Pimenta-Marques and Mónica Bettencourt-Dias review how their structure and functions are maintained.

Marian Blanca Ramírez from the CSIC in Spain has been studying the effects of LRRK2, a protein associated with Parkinson’s disease, on cell motility. A Travelling Fellowship from Journal of Cell Science allowed her to spend time in Prof Maddy Parson’s lab at King’s College London, learning new cell migration assays and analysing fibroblasts cultured from individuals with Parkinson’s. Read more on her story here.

Where could your research take you? The deadline to apply for the current round of Travelling Fellowships is 30 Nov 2017. Apply now!