Indianapolis Colts quarterback Andrew Luck dejectedly paces the sidelines during the second half against the Arizona Cardinals on Sunday. The Cardinals defeated the Colts 40-11.

A little over a month ago, the Indianapolis Colts were a true-blue Super Bowl contender. They had knocked off the 49ers in San Francisco, beaten Seattle and Denver at home, and all seemed right with the world despite the spate of injuries that hit the team's offense.

Then Reggie Wayne got hurt late in the Broncos game.

Everything changed.

This has not been close to the same team since it lost Wayne, having moved to 2-2 without him after Sunday's breathtakingly awful 40-11 loss to the Arizona Cardinals.