Curriculum Vitae

Associate Professor ANDREW PAUL BARBOUR

MBBS, PhD, FRACS
General Surgeon specialising in Upper GI, Melanoma and Soft Tissue
University of Queensland, School of Medicine
Discipline of Surgery

Qualifications

1988 – 1992

MBBS (Honours)
University of Queensland

2002

Doctor of Philosophy (PhD)
University of Queensland

2003

FRACS
Fellow Royal Australasian College of Surgeons

2010

FACS
Fellow American College of Surgeons

Medical Licensure

Queensland Medical Board
Annual Practising Certificate No. 940374

General Medical Council (United Kingdom)

New York Medical Board
Limited Permit to Practice Medicine

Distinctions & Awards

2012

James IV Association Travelling Fellow (2013)

2009

American College of Surgeons (ACS) International Scholarship

2002

Queensland Cancer Fund Travelling Scholarship

2001

American Association for Cancer Research Scholar in Cancer Research Award

2001

RACS Travelling Fellowship

2000

Princess Alexandra Hospital Society Travel Grant

1999-2000

NH&MRC Post-graduate Medical Research Scholarship

1999-2000

RACS Surgeon Scientist Fellowship

1998

Princess Alexandra Hospital Registrar’s Prize

Professional Memberships

Australia and New Zealand Gastro-Oesophageal Surgeons Association (ANZGOSA, Current)
Australia and New Zealand Hepato-Pancreatico-Biliary Association (ANZHPBA, Current)
International Society for Disease of the Esophagus (ISDE, Current)
Australian Sarcoma Group (ASG, current)
Australian Sarcoma Study Group (ASSG, Current)
Australian Melanoma Trials Group
American Association for Cancer Research
Australian Gastrointestinal Trials Group (AGITG, Current)
International Society of Gastric Cancer (Current)
Gastroenterological Society of Australia (Current)
Surgical Research Society of Australasia (Current)
Clinical Oncological Society of Australia (COSA, Current)
Gastroenterological Society of Queensland (GESA, Current)
Royal Australasian College of Surgeons (Current)
American College of Surgeons (ACS, Current)
Society of Surgical Oncology (SSO, Current)

Appointments

October 2005 – current

Senior Lecturer
University of Queensland, School of Medicine
Discipline of Surgery
Princess Alexandra Hospital Woolloongabba, QLD

Research

Throughout my career I have maintained a commitment to the academic aspects of surgical practice as well as clinical care of patients. My major research themes are Upper GI malignancy, melanoma and soft tissue sarcoma. My academic interests have encompassed the areas of 1) clinical research, including randomised controlled clinical trials, 2) laboratory based research, including molecular biology pertinent to upper gastrointestinal disease and melanoma, 3) translational research integrating the laboratory and clinical domains.

As a clinical researcher, I have been active in the conduct of clinical trials at Phase I, II and III levels. This has culminated in the development of a randomised phase II trial of preoperative chemotherapy or chemo-radiotherapy based on poor early response to standard chemotherapy for resectable oesophageal cancer (DOCTOR trial, NHMRC APP #1011782) as CIA. I am also the principal investigator on an investigator initiated, AGITG-sponsored phase II clinical trial of pre-operative chemotherapy for pancreatic cancer (GAP trial). Both of these national trials include biological substudies with tumour tissue and blood banking and subsequent molecular analyses aimed at answering specific questions, including the identification of biomarkers of response to therapy. The GAP translational study (GAP-T) is funded by NHMRC (APP#1026563).

As a translational researcher at the School of Medicine, PAH, University of Queensland, I am the head of Surgical Oncology Lab at the School of Medicine. My research has focused on using genomic, epigenomic and expression data to classify oesophageal adenocarcinoma (OAC) and identify biomarkers of outcome (Cancer Council Queensland Project Grant #631544). We will be undertaking a comprehensive genomic study of OAC, including next generation sequencing, commencing in 2012 (APP#1021403). These studies are focussed on the large number of well curated tumour tissue bank OAC specimens with accompanying clinical data available at the PAH. As a result, I have expertise in the analysis of cancer using cDNA microarrays and SNP arrays.

Research Collaborations

2012

PROBE-NET: The Progression of Barrett's Esophagus to Cancer Network (NHMRC CRE $2,465,841, CIA Whiteman) This application brings together the seven major research teams in Australia with expertise in oesophageal cancer to form a multi-state, multi-disciplinary Centre of Research Excellence. All of the nodes have worked together collaboratively for the past 4 years, pooling their expertise in surgery, gastroenterology, endoscopy, epidemiology, biostatistics, basic science, health policy and translational research. The vision is to develop evidence-based strategies for reducing the burden of oesophageal neoplasia.

Human papilloma virus in squamous carcinoma of the oesophagus with Prof Raina MacIntyre, Professor Infectious Diseases Epidemiology and Head of School of Public Health and Community Medicine, The University of New South Wales.

2009

Collaboration with Dr David Whiteman, Dr Derek Nancarrow and Dr Nick Hayward (QIMR) to investigate genome-wide analyses for the identification of biomarkers in oesophageal adenocarcinoma.

Teaching

I continue to be involved in teaching students involved in the MBBS program within my 0.4 FTE appointment. This predominately relates to those in the second (MEDI2006) to third years (MEDI3003). I have been System Leader for the gastrointestinal and musculoskeletal systems for years one and two. I have been responsible for the teaching of a group of third year medical students for each surgical rotation at the PA Hospital. I remain committed to teaching students and attending the examination sessions.

I am closely involved in the teaching and guidance of FRACS advanced surgical trainees and with Surgeons working as fellows / senior registrars at the Princess Alexandra Hospital. The teaching occurs formally in sessions and informally in the clinics and the operating theatre. I am also strongly committed to mentoring both medical student and junior medical staff. I have arranged formal sessions in career development with the surgical trainees, specifically directed at encouraging academic surgery.

I have proposed and implemented changes to the post graduate teaching program at Princess Alexandra Hospital that emphasizes the interpretation of available evidence, its application to a specific case and presentation skills.

I am frequently asked to give lectures to surgical and medical groups dealing with areas of my expertise. I am requested to give lectures at General Practice education evenings in Brisbane. In addition I have been an invited speaker at major skin cancer conferences and have provided Melanoma education for the Cancer Council Queensland (TCCQ) Volunteers.

NH&MRC Melanoma guidelines: Appropriate use of investigations chapter and Follow up chapter
These are the national guidelines for the treatment of melanoma for general practitioners and specialist medical practitioners. The guidelines have been reviewed and commended by the NIH melanoma group.

Invited Presentations

Barbour, A. The role of Endoscopic Ultrasound and Adequate Staging for Patients with Adenocarcinoma of the Gastro-Oesophageal Junction. Australian Gastrointestinal Trials Group, Annual Meeting, Brisbane, Australia.