Background and Aim: Kinds of job and body posture during work are among main risk factors for varicose veins. Among different jobs, nursing needs high mobility, long time standing and tiring physical positions that are necessary in performing nursing duty. This survey aimed at determining lower body organs varicose veins prevalence and its relationship with some risk factors among registered nurses in Birjand University of Medical Sciences Hospital'sMaterial and Methods: In this descriptive- analytical survey, all registered nurses (including nurses and auxiliary nurses) worked in Imam Reza and Valiyye-Asr hospitals were chosen as the research population. Sampling was done by numeric method and 124 people who were willing to participate in the research were surveyed. After primary surveys, library studies, and making a questionnaire, all of the samples were examined and low body organs veins were tested and varicose severity was determined through CEAP scale. Subjects’ height and weight were also measured and demographic information and other variations were recorded. The obtained data ere analyzed through SPSS software, Chi-Square, Exact Fisher Tests, and one-way variance analysis at the significant level P<0.05.Results; All the 124 subjects were female, 71.8 percent of whom were academic nurses and 28.2 percent were auxiliary nurses. Their mean age was 32.7 years and their mean employment time was 10.3 years, mean working hours per week was 185 hours for nurses and 171 for auxiliary nurse's subjects mean weight and height were 62.02 kg and 159.12 cm. Out of 124 cases, 68.3% had B.Sc., 30. 9% had diploma and 1.6 % had post-graduate
studies. A vast majority of the subjects (87.8%) were married and 12% were single. Out of 124 cases, 43.5% had mild (grade 1), 18.5% moderate (grade 2) and 3.2% had severe (grade 3) varicose veins, 34.7 percent of them had no signs of varicose veins. Statistical analysis showed significant relationship between varicose veins severity and job level (P=0.000), number of pregnancies (P=0.000), number of deliveries (P=0.000), marriage status (P=0.05), education level (P=0.000), weight (P=0.01), working time length (P=0.000), standing time length (P=0.003), sitting (P=0.002), walking (P=0.05) and heavy objects lifting during work. But there was no significant statistical relationship between varicose veins severity and monthly work hours, height, surgical history, chronic diseases, hormone therapy, oral contraceptive use and number of abortions.Conclusion: This survey revealed that varicose veins prevalence in employee nurses is high and it has relationship with weekly work hours and body posture during work.. Varicose vein is one of the trombotic risk factors and can cause several mental and physical complications and thus professional disability. It therefore is necessary to control the risk factors by a good preventive implementation.