Tag: "precursors" at biology news

...fat is initiated. Without this signal, muscle-cell precursors can even be reprogrammed to undergo adipogenesis, ...he picture. Disrupting Wnt signaling caused muscle precursors to go soft and transform into fat. The Wnt family of cell signalers includes more than 20 differen...

...shington, D.C. "We have been able to assemble six precursors of the 19 known disaccharides that make up Heparin. These precursors can be used either as donors or acceptors in assembling larger Heparin structures," said chemist Gee...

...eficient cultures failed to accumulate osteoclast precursors in response to ethanol or to upregulate expression of RANK ligand, which promotes the formation of mature osteoclasts. By several measures, bone mass was better maintained in alcohol-fed IL6-/- mice than in wild type animals, suggesting that the los...

...s - those cells in the ovary that are the earliest precursors to eggs. According to the scientists, their findings offer a potentially valuable model to explore how stem cells are regulated in vivo . "The idea that stem cells require niches - local environments of surrounding cells that are important for the...

...ghts into its molecular basis. Smooth muscle cell precursors become stretched as fluid accumulates in the lumen of the developing lung, and the authors show that this mechanical deformation is sufficient to induce the expression of several differentiation-dependent smooth muscle cell proteins. Stretching of c...

..., giving them a second chance. Nitrogen oxides are precursors to ozone formation. Surface ozone in the Arctic is depleted during sunlit periods, and it has been determined that a significant portion of this destruction may occur within the snowpack. Photochemistry within the snowpack can lead to creation of fre...

... that two chemicals found in sea salt may serve as precursors to initiate a series of chemical events that destr... The study traces the source of those chemical precursors to the salty minerals found in sea water that is carried into the snowpack in the form of tiny salt ...

... to make the nuclear industry safer to identifying precursors to airline accidents. By studying and coding the chains of events that contribute to or cause aviation accidents, researchers hope to prevent similar accidents in the future. In another project for the Federal Aviation Administration, researchers are...

...hological changes in the skin known to be melanoma precursors were documented in many of the mice, with overt melanoma seen in some. The first author on the study is Carola Berking, M.D. Other Wistar co-authors include Richelle Takemoto, B.S., and Kapaettu Satyamoorthy, Ph.D. Rosalie Elenitsas with the Universi...

...l explore the current hypothesis that the chemical precursors of life originated in outer space, not on Earth as previously thought. The famous Miller-Urey experiments of the 1950s assumed that early Earth was replete with water and atmospheric gases such as hydrogen, methane and ammonia, much as Jupite...

...sium will explore the hypothesis that the chemical precursors of life originated in outer space, not on Earth as previously thought. (GEOC 144-151, 167-173; Wednesday-Thursday, April 4-5.) Fighting incontinence - A promising class of compounds could be used to develop a better drug for urinary incontinence...

...gene that prompts embryonic stem cells to generate precursors to most internal organs. The finding suggests a potent new way of coaxing stem cells to produce high numbers of specialized cells that can form medically needed tissues such as insulin-producing pancreatic cells, the scientists say. The research led ...

...y have for the first time succeeded in growing the precursors of heart cells from human embryonic stems cells. This puts the researchers considerably closer to clinical application in humans. The research, conducted by Dr. Lior Gepstein of the Faculty of Medicine at the Technion-Israel Institute of Technology...

...minishing the growth of myeloid and erythroid cell precursors alike. Interestingly, these JZ1.1 T cells appear to be specific for autologous stem cells derived from the patient at a time of severe disease marrow cells derived from a healthy, MHC-matched control donor, or even from the patient after successful ...

...d in the final rearranged immunoglobulin as B cell precursors mature. Although this process is essentially random, VH regions are not uniformly distributed among mature, IgG-secreting plasma cells, because these cells are subject to both positive and negative selection as they mature. In particular, B cells ex...

...by binding to hormone receptors found only in rare precursors within adult bone marrow. Igarashi found that the receptors were not expressed on corresponding cells of the fetus. Indeed, the receptors are expressed after birth in experimental animals and man. By lacking these receptors, the immune system of ...

... naturally occurring or derived from their natural precursors which could lead directly to development of new compounds for lowering cholesterol. Koo anticipates that regulatory barriers to such development will be low. Koo says people with normal cholesterol levels and no family history of cardiovascular disea...

...the mechanisms that generate germ cells, which are precursors to adult reproductive organs. She has also identified how initial asymmetry of the embryo, necessary for the development of specialized tissues, derives from the interaction of specific structures within the ovum and sperm at fertilization. "Her wo...

...ortant area of investigation because they serve as precursors for all adult cells. Stem cells start out as blank slates, but by receiving signals from specific genes and proteins they become associated with certain parts of the body and responsible for specialized functions. "We stand to learn a great deal from...

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