HUMIRA: moderate to severe rheumatoid arthritis (RA) treatment

Spotlight on HUMIRA: RA Treatment

HUMIRA can help relieve pain and swelling—and help prevent further joint damage.

Maybe you’ve accepted the morning stiffness that comes with moderate to severe RA as your “new normal.” You may not have to. Many people with RA who’ve tried HUMIRA are once again able to do some of the things they love.

HUMIRA is a prescription medicine used alone, with methotrexate, or with certain other medicines to reduce the signs and symptoms of moderate to severe rheumatoid arthritis in adults, may prevent further damage to your bones and joints, and may help your ability to perform daily activities.

Some rheumatoid arthritis patients notice less joint pain, swelling and stiffness in as little as 2 weeks. For others, it may take up to 3 months or longer. Individual results may vary.

These results were seen in people taking HUMIRA in combination with methotrexate for moderate to severe RA.

How long does your morning stiffness last?

See how others responded.

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Up to 30 minutes

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30 minutes to 1 hour

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More than 1 hour

Morning stiffness lasting more than half an hour, especially in pairs of joints, can be an indication of moderate to severe RA.

HUMIRA and methotrexate—a combination that has demonstrated results.

Your doctor may prescribe HUMIRA together with methotrexate for your moderate to severe RA. Studies have shown that people taking HUMIRA and methotrexate had fewer symptoms and slower progression of joint damage than those taking methotrexate alone.

In a study of moderate to severe RA patients diagnosed for an average of 11 years who added HUMIRA to methotrexate:

63% of people who took HUMIRA with methotrexate saw improvement in RA signs and symptoms (compared to 30% of people taking methotrexate alone)

When compared with methotrexate alone in a clinical study, more people taking HUMIRA and methotrexate saw a 20% improvement in the signs and symptoms of RA at 6 months

In a separate study of patients with moderate to severe rheumatoid arthritis (diagnosed for less than three years and not previously treated with methotrexate), combining HUMIRA and methotrexate showed:

64% of people taking HUMIRA with methotrexate had no further joint damage 1 year after treatment (compared to 37% of people taking methotrexate alone)

The combination, on average, was 5 times more effective at slowing the progression of joint damage than methotrexate alone after 2 years

HUMIRA has been prescribed over 15 years.

1997

Clinical trial experience: beginning with RA, first patient dosed in April 1997

2002

HUMIRA is approved to treat moderate to severe rheumatoid arthritis

2005

HUMIRA is approved to treat psoriatic arthritis

2008

HUMIRA is approved to treat moderate to severe polyarticular juvenile idiopathic arthritis in children 4 years of age or older

2015

As of December 2015, HUMIRA patients currently treated worldwide was 955,717*

*Across all approved indications

HUMIRA Use for Psoriatic Arthritis

HUMIRA is a prescription medicine used alone or with certain other medicines to reduce the signs and symptoms of psoriatic arthritis in adults, may prevent further damage to your bones and joints, and may help your ability to perform daily activities.

HUMIRA Use for Juvenile Idiopathic Arthritis

HUMIRA is a prescription medicine used alone, with methotrexate, or with certain other medicines to reduce the signs and symptoms of moderate to severe polyarticular juvenile idiopathic arthritis in children 2 years of age and older.