x-linked

A useful but unwieldy CMT classification system helps make sense of the many subtypes of the disease

posted on July 1, 2011 - 2:17pm

As recently as the early 1990s, many experts hoped that understanding just a few genes that influenced the development or maintenance of myelin or axons would explain all of Charcot-Marie-Tooth disease.
It didn’t turn out to be that simple, however. Today, there are dozens of genes recognized that, when flawed, can cause CMT.