They were America's children, symbolic of hope and youth, then of tragedy, and finally of the enduring power of the Kennedy legacy. In the 255 vibrant photographs in this book - mostly never before published - we watch John and Caroline grow up in the adoring, and sometimes harsh, glare of public attention.

They were the youngest children to live in the White House in over a century - Caroline just three and John Jr. a newborn when their father took the oath of office. Symbolizing the youthful vigor of the new administration, they won the hearts of the American people as they romped around - and under - their father's desk in the Oval Office. And when, three years later, Caroline kissed JKF's coffin and John Jr. saluted the passing bier, they were forever etched into the nations' collective heart.

We see their awkward adolescence, their sorrows at senseless losses in the family, their first forays into romance, their efforts to establish themselves as responsible adults, their happy marriages and Caroline's motherhood. And we watch in admiration as Caroline recovers from the untimely death of her beloved brother to assume the mantle of the Camelot legend.

This is a book that will tug at the heart-strings of all who remember fondly these two remarkable American offspring.

Julia Roberts represents a return to the glamour of the great Hollywood stars of another era. Fans flock to her movies, and she's a staple cover subject of People magazine and every entertainment show imaginable, but her real life has only been seen in tabloid glimpses until now. James Spada has gone back to Julia's beginnings in Athens, Georgia to unearth fascinating facts about her family and her early dating life. And he's followed her career from movie to movie-both on screen and behind the screen-to show fans what the private face of Julia really is.

As an artist, Julia has changed dramatically from the talented but sheltered girl who found fame first with a role in the independent movie "Mystic Pizza" and became the exuberant star whose "Pretty Woman" delighted audiences everywhere before becoming an Oscar-winning actress capable of taking on the toughest roles. As a person, she's grown from a skittish and gangly girl moving through relationships with co-stars to become an assured woman making her own bold decisions about how to live her life.

Julia will delight fans with its level of detail and fresh information, as well as its thoughtfulness about the life and career of a truly vibrant and complex star.

Biopharmaceuticals, the term for genetically engineered therapeutic proteins, monoclonal antibodies, and nucleic acid-based products, have become an increasing part of the pharmaceutical armament. While this category of drugs accounts for approximately 25% of all new drugs coming to market, very few references exist that review these commercially available products. Until now, accessing data on the list of currently approved biopharmaceuticals has been laborious and patchy.

Directory of Approved Biopharmaceutical Products brings together key information on various aspects of these compounds, presenting a brief summary of each biopharmaceutical currently approved for medical use. Each summary includes the scientific and trade name, year and regions approved, approved indications, manufacturer, marketing right, method of manufacture, scientific overview, and therapeutic properties. Based on information gathered from regulatory agencies and pharmaceutical manufacturers, the book presents the most comprehensive data currently available in a single, convenient volume.

This comprehensive and consistent approach will save professionals in the pharmaceutical industry hours spent trawling the literature - and provides a singular resource for future reference.

A legendary life shown in rare, mostly never before published photographs. Arguably the most famous woman of the twentieth century, certainly one of its most photographed, Jacqueline Bouvier Kennedy Onassis lived an astonishing life; her popularity and the fascination she held for people the world over during her nearly sixty years in the spotlight can hardly be overestimated. And while that has led to a number of books about her, none has told her life story in the way this one does--entirely in photographs, from birth to death, with lively, anecdotal extended captions. Of the 251 photographs in Jackie: Her Life in Pictures, 165 have never been published, 58 have rarely been published (in newspapers or magazines but never in book form), and 28 are inescapable images that have been seared into the memories of everyone. Together with the text by James Spada that runs alongside them, these pictures tell the story of an American life that became legendary even while it was being lived, a story that will speak afresh to the hearts of all Americans.

Thirteen-year-old Jason Sorenson has nothing left to lose. Following a tragic car accident, his family is dead, and his leg is mangled. The courts send him to Washington to live with an uncle he’s never met. To him, Washington is a strange and unfamiliar place, and it certainly isn’t easy to make new friends ... until he stumbles upon the ruins of an ancient Native American village nearby.

So begins an unplanned journey for Jason, one that won’t be easy. The Native American culture is even more foreign to him than the state of Washington. When he meets Crystal Clearwater, things come into focus, but Jason can’t tell if it’s his newfound knowledge of her culture or the girl herself. Things get more complicated when some of the bullies in her tribe don’t take too kindly to an outsider falling for one of their people.

Together, Jason and Crystal unearth artifacts that seem almost magical. They also stumble over human bones, the discovery of which opens up a whole lot of questions for the locals. As time passes, Jason needs Crystal’s help to make sense of it all. He also forges an unexpected bond with his Uncle Jake in the process. Maybe Washington isn’t so bad after all, and maybe treasure is not always buried in the ground.

Teachers are often told that new teaching methods and materials are 'based on the latest research'. But what does this mean in practice? This book introduces you to some of the language acquisition research that will help you not just to evaluate existing materials, but also to adapt and use them in a way that fits what we currently understand about how languages are learned.

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