2

Bleeding/bruising:
Factor viii deficiency or hemophilia- is a bleeding disorder. It is hereditary in most cases . The symptoms would be spontaneous bleeding- either in the joints, skin/gum, or other places etc or prolonged bleeding. The severity of bleeding will depend on how low the level of the factor viii is.. Usually the bleeding episodes will manifest at early age. Discuss further with your hematologist.
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4

Yes, in men:
Hemophilia is a sex linked disorder and men develop the disease when there only x chromosome has the defective gene. See this site for more info.
http://www.nlm.nih.gov/medlineplus/ency/article/000538.htm.
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5

Factor VIII:
Concentrate. Factor viii is prepared by recombinant technology, though it may also be extracted from human plasma. Depending on the severity of deficiency, factor viii may be given prophylactically or to treat episodes of bleeding. The drug is given intravenously.
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9

Bleeding/bruising:
Factor viii deficiency or hemophilia- is a bleeding disorder. It is hereditary in most cases . The symptoms would be spontaneous bleeding- either in the joints, skin/gum, or other places etc or prolonged bleeding. The severity of bleeding will depend on how low the level of the factor viii is.. Usually the bleeding episodes will manifest at early age. Discuss further with your hematologist.
...Read more

13

Yes, in men:
Hemophilia is a sex linked disorder and men develop the disease when there only x chromosome has the defective gene. See this site for more info.
http://www.nlm.nih.gov/medlineplus/ency/article/000538.htm.
...Read more

14

Factor VIII:
Concentrate. Factor viii is prepared by recombinant technology, though it may also be extracted from human plasma. Depending on the severity of deficiency, factor viii may be given prophylactically or to treat episodes of bleeding. The drug is given intravenously.
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15

Xfusion with factor-:
-Vlll, then aspiration of the joint. Chronic hemarthrosis destroys the articular cartilages. It consumes O2, & does not allow it 2 B nourished. Cartilages only O2 comes from the joint fluid, but it's not available since the inflammatory reaction 2 the blood consumes it
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PTT and ARR:
Are a mildly elevated PTT and mildly elevated Coagulation Factor VIII Activity, as all as a high ALDO/PRA RATIO something to be concerned about and is there a correlation? ANS: no and No. I specialize in ARR problems. Happy to do 2nd opinion.
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18

Blood clotting:
Factor viii is a clotting factor. This is one of many that help you stop bleeding from a cut. If you are low on factor 8, then you will bleed longer than someone who has normal factor 8. The associated condition is called hemophilia a. Treatment is done by replacing the factor 8 when necessary, such as after a trauma or surgery. In severe cases, you may be given factor 8 regularly for prevention.
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19

Antibody to factor:
Viii protein. People who are deficient in factor viii, i.e., have severe hemophilia, are treated with infusion of factor viii. Some make antibodies to factor viii and inhibit its function and are called factor viii inhibitors. Rarely non-hemophiliac can also develop such an inhibitor.
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20

No.:
Plasmapheresis removes all the clotting proteins, including factor viii, but the body rapidly replaces what is taken out. Usually all proteins are back to their usual levels within 24 hours. This would not be long enough to provide meaningful anti-coagulation.
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