Mays suffered a fractured fibula near his ankle after being inadvertently leg-whipped by a Saints player.

With the injury, a difficult season appears to be over for Mays, who was handed a $50,000 fine and a one-game suspension by the NFL for his hit on Houston Texans quarterback Matt Schaub in Week 3. Back in March, things were looking better for Mays when he signed a three-year contract worth $12 million.

The Broncos could promote Mike Mohamed from their practice squad to take Mays' roster spot. They'll also get linebacker D.J. Williams back from his second suspension in a couple of weeks.