Thank you for your reply.Unfortunately, my information on this family is very limited.It would probably be a good idea to check the census for Madison Co., IL to try to follow the family.Researching land records there may also be helpful.If land were purchased by him but never sold, it would indicate he probably stayed there. There are a lot of Isaac Weatherbys in this time frame.There were several in Ohio that I came across when I was trying to research this particular Isaac. If you believe your Isaac was in Ohio, it would be a good idea to use census, IGI, and other genealogical sites to search for the correct one.I wish I could be of more help.G. Ennis