Washington (CNN) - With an incoming freshman class of conservative and Tea Party Republicans skewing the GOP conference to the right, there will be little mood for compromise or bipartisan legislation on any major issues in the House, most observers say.

Ron Bonjean, a Republican strategist who worked for the last Republican House speaker, Dennis Hastert, put it bluntly:" It's been a hostile atmosphere, but it will be hostile on nitroglycerin."

While Ohio Republican Rep. John Boehner, who would be the next speaker should Republicans regain control of the House, plans reforms that he says will make the chamber work better, he's already signaled he's not planning to negotiate with the White House or congressional Democrats on his party's top priorities.FULL STORY