M.L. Heijnenhttp://repub.eur.nl/ppl/10524/
List of Publicationsenhttp://repub.eur.nl/eur_signature.pnghttp://repub.eur.nl/
RePub, Erasmus University RepositoryHepatitis B vaccination targeted at behavioural risk groups in the Netherlands: Does it work?http://repub.eur.nl/pub/16057/
Tue, 02 Jun 2009 00:00:01 GMT<div>R. van Houdt</div><div>F.D.H. Koedijk</div><div>S.M. Bruisten</div><div>E.L.M. Op de Coul</div><div>M.L. Heijnen</div><div>Q. Waldhober</div><div>I.K. Veldhuijzen</div><div>J.H. Richardus</div><div>M. Schutten</div><div>G.J.J. van Doornum</div><div>R.A. de Man</div><div>S.J. Hahné</div><div>R.A. Coutinho</div><div>H.J. Boot</div>
In November 2002, the Netherlands adopted a vaccination program targeted at behavioural risk groups. Between January 2003 and December 2007, 1386 patients acutely infected with HBV were reported. Reported cases declined from 326 in 2003 to 220 in 2007. Sexual intercourse was the most frequently reported mode of transmission (65%), especially among men having sex with men. Genotypes A and D remained predominant. In total, 40,600 participants were fully vaccinated, the overall compliance was 62%, and the estimated overall program coverage was 12% of the at-risk population. With more effort, more susceptibles may be reached, but the program will not be sufficient to substantially reduce HBV in the Netherlands. Therefore, universal vaccination should be considered.Respiratory infections in infants: Interaction of parental allergy, child care, and siblings - The PIAMA studyhttp://repub.eur.nl/pub/64048/
Sat, 20 Oct 2001 00:00:01 GMT<div>L.P. Koopman</div><div>H.J. Neijens</div><div>H.A. Smit</div><div>M.L. Heijnen</div><div>A.H. Wijga</div><div>R.T. van Strien</div><div>M. Kerkhof</div><div>J. Gerritsen</div><div>B. Brunekreef</div><div>J.C. de Jongste</div>
Respiratory infections in infants: interaction of parental allergy, child care, and siblings-- The PIAMA studyhttp://repub.eur.nl/pub/9766/
Mon, 01 Jan 2001 00:00:01 GMT<div>L.P. Koopman</div><div>H.A. Smit</div><div>M.L. Heijnen</div><div>A.H. Wijga</div><div>R.T. van Strien</div><div>M. Kerkhof</div><div>J. Gerritsen</div><div>B. Brunekreef</div><div>J.C. de Jongste</div><div>H.J. Neijens</div>
OBJECTIVE: To investigate the association between contacts with other
children and the development of respiratory infections in the first year
of life in children with or without genetic predisposition for allergy.
METHODS: Children (n = 4146) who participate in a prospective birth cohort
study (Prevention and Incidence of Asthma and Mite Allergy study) were
investigated. Questionnaires were used to obtain information on
doctor-diagnosed upper respiratory tract infection (URTI) and lower
respiratory tract infection (LRTI), child care attendance, having
siblings, family history of allergic disease, and various potential
confounders. RESULTS: Child care attendance in the first year of life was
associated with doctor-diagnosed URTI (adjusted odds ratio [AOR]: 2.7; 95%
confidence interval [CI]: 2.1-3.4 for large child care facility vs no
child care) and doctor-diagnosed LRTI (AOR: 5.6; 95% CI: 3.9-7.9). Having
siblings was associated with doctor-diagnosed LRTI (AOR: 2.6; 95% CI:
2.0-3.4). In addition, children who have allergic parents and attend child
care or have older siblings have a higher risk of developing
doctor-diagnosed LRTI than do children who have nonallergic parents.
CONCLUSIONS: Child care attendance or having siblings increases the risk
of developing doctor-diagnosed LRTI in the first year of life to a greater
extent in allergy-prone children than in children who are not allergy
prone.