Profiles contain automatic settings for the best performance/visuals. They can be adjusted/tweaked, but really, it's meant so that optimizations can be carried from driver version to driver version. This means you can use older stable driver that offers the functionality, but still get the benefit of new optimizations that you'd not normally have access to without installation of a new driver.

That means that you do not have to update your driver every month any more. You can simply just update the App Profile instead.

Hey dark, you may want to update that line in red in the OP.
CAPs are also for single card setups; they are called Catalyst Application Profiles, not Crossfire Application Profiles which is a misconception.

new CAP out, OP updated, rage3d.com has a dated database of CAP changes (stops at 11.12, so all the 12.x CAPS might need some googling) for people to browse and see what games have single card enhancements involved.

Not to make a huge argument, then why would AMD state on the download page that lists all the drivers and other software, state that the CAPs should not be installed with the 13.5 Betas? They stated the same thing with the 13.3 Betas too.

I did drop them an email asking about single card setups as that only really posts for Crossfire users, but I don't remember with the 13.3s there being anything Crossfire specific. Wouldn't be terribly surprised though if it didn't affect performance as all, just double up on info already provided in the driver.