アプリケーション

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション

Abreviews

特記事項

WB

1/2000. Predicted molecular weight: 100.9 kDa.

IHC-P

Use at an assay dependent concentration. PubMed: 24294399

ターゲット情報

関連性

SPON1 is a member of a subgroup of the thrombospondin type 1 (TSR) class molecules, defined by two domains of homology, the FS1/FS2 and TSR domains. The TSRs of SPON1 proteins are typical of class 2 TSRs.
SPON1, which is similar to thrombospondin, is a extracellular matrix attached molecule that promotes neurite outgrowth and inhibits angiogenesis. Analysis of gain and loss of function experiments reveal that SPON1 is required for accurate pathfinding of embryonic axons, and plays a dual role in patterning axonal trajectories. It promotes the outgrowth of commissural and inhibits the outgrowth of motor axons, and has also been implicated in inflammatory processes in the nervous system.

Thank you for taking the time to provide all the protocol details, it was very useful to understand the problem.
Could you please tell me the batch number of the first order, we have several records of selling to GeneResearch ab14271 in the last few...

I'm sorry to hear you are experiencing a problem with ab14271.
Thank you for providing so many details about your protocol, I was very useful for me to understand your problem and I am confident that there the antibody is at fault. Unfortunately, I h...

Thank you for your e-mail.
From the Swiss prot information the reelin domain is from aa 29-194 of spondin 1. However the immunogen sequence is located towards the carboxy end of the protein (it is located at aa 549-807 and the whole protein is 807aa l...

Thank you for your enquiry. I will attempt to answer your enquiries point by point.
1) Where 20ug is denoted as the loading amount on a WB blot this denotes total protein and not purified target protein. 100ng in the on line protocol refers to the p...

Thank you for you inquiry.
Once an order has been placed for this antibody, it takes approximately 7 to 10 days for it to come into stock. Please contact us again if you have any other questions regarding our products.

Abcam Scientific Support

Answered on Aug 13 2004

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"