Institute of Biological Sciences,
University of Wales,
Aberystwyth SY23 3DA,
United Kingdom

Language(s)

English

Publication date

2005-10-04

Subject

Summary, abstract or table of contents

Abstract:

There is current debate whether genetically modified (GM) plants
might contain unexpected, potentially undesirable changes in
overall metabolite composition. However, appropriate analytical
technology and acceptable metrics of compositional similarity
require development. We describe a comprehensive comparison of
total metabolites in field-grown GM and conventional potato tubers
using a hierarchical approach initiating with rapid metabolome
"fingerprinting" to guide more detailed profiling of metabolites
where significant differences are suspected. Central to this
strategy are data analysis procedures able to generate validated,
reproducible metrics of comparison from complex metabolome data. We
show that, apart from targeted changes, these GM potatoes in this
study appear substantially equivalent to traditional cultivars.

Thematic areas

Scientific and technical issues

Risk assessment

Background material to the “Guidance on risk assessment of living modified organisms”

Is this document is recommend as background material for the “Guidance on Risk Assessment of Living Modified Organisms”

Section(s) of the “Guidance on Risk Assessment of Living Modified Organisms” this background material is relevant

1. Roadmap for risk assessment of living modified organisms

1.5. Conducting the risk assessment

1.5.1. Step 1: “Identification of any novel genotypic and phenotypic characteristics associated with the living modified organism that may have adverse effects on biological diversity in the likely potential receiving environment, taking also into account risks to human health”