The major U.S. indexes spiraled lower amid a collision of negative sentiment stemming from tension in the Middle East, rising oil prices and the latest drug recall.

THE MAJOR U.S. INDEXES spiraled lower amid a collision of negative sentiment stemming from tension in the Middle East, rising oil prices and the latest drug recall.

Taking its cue, the Dow Jones Industrial Average plummeted 75.37, or 0.7%, to close at 10766.23. The Standard & Poor's 500 slipped 7.77, or 0.7%, to 1203.60. The tech-heavy Nasdaq Composite Index rose dropped 13.68, or 0.7%, to 2051.72.