Dysfunction
and deficits in the structure of the anterior cingulate cortex (ACC) have
been reported in borderline personality disorder (BPD). Impulsivity belongs
to the key features of BPD and can be related to ACC function. In this study
we found significantly increased self-reported impulsivity and higher levels
of glutamate in the anterior cingulate cortex in subjects with BPD as
compared to healthy controls. In both groups the ACC glutamate concentrations
were positively correlated with self-reported impulsivity.