Since I started Humira I've been feeling a lot better than before Humira. But there's one problem. I've been taking it for a little over 5 months and have gained 16 pounds. The doctor insists it has nothing to do with the Humira but I had weighed 175 consistently for 6 years and since starting Humira I go up to 191! When I saw those numbers on the scale I couldn't believe it! I wasn't told I would gain weight on humira. My diet hasn't changed and I still exercise about an hour daily so it has to be the humira. But my doctor continues to insist it has nothing to do with the Humira. I'm scared the next time I climb up on the scale I'll have gone up 40 pounds. I'm also having a hard time losing it has anyone else had this problem while on Humira or does it really have nothing to do with the medicine itself. Oh and if it is related will taking more of it making me gain even more weight because my doctor upped the dosage to once every 10 days instead of once every 2 weeks.

A study done of patients with rheumatoid arthritis on a variety of anti-TNF meds like Humira found that these meds do cause weight gain in some patients. I will try to find the study and give you a link in case you want to print it out for the doctor.Moderator Crohn's disease, Osteoarthritis and Irritable Bowel Forums

I'm not sure how bad your case was, but it could be too that you are absorbing a lot more nutrients then you were in pass because things are starting to heal up..just a thought.Diagnosed Nov 2008Brother also has Crohn's.Currently on Humira, LDN, and Ciprofloaxcin I'm 20 years old.I want to be a Gastro Doctor ; )

My thoughts were along the lines of what Endeavor said. I don't know about weight gain side effect with Humira, all else being equal, but if the Humira is doing its job - all else is not equal - your intestines are better and absorbing more nutrients, calories, etc. Just my opinion.Crohn's Disease for 22 yearsDiagnosed in Feb 1989 at age 14

Ditto with the previous responses. If the humira is working then remission I'd being found to some extent allowing the small intestine to absorb more then before. Although your weight before hovered around 175 maybe that was because it was under the influence of crohns...

Thanks for all of your responses. As long as I don't continue to gain weight I'll be fine:) Because I love humira, I haven't felt as good as I feel now in years so I really can't complain. I just don't want to wake up one day and have gained 100 pounds!Diagonosed with Crohn's of the Large and Small Intestines Sept 2010 had been suffering for a year and a half beforePreviously had 3 fistulas and 3 abscesses Meds: Starting Humira 10/17/2010