Randle's 17 first-half points staked Kentucky (10-3) to a 41-36 halftime lead before the 6-foot-9 forward went to the locker room early in the second with leg cramps.

He returned but cramped again and spent the rest of the game on the bench.

The Harrison twins amply filled the void, turning a 52-51 deficit with 11:01 remaining into a 68-58 lead with four minutes left. Andrew Harrison and James Young each scored 18 points with Young adding a key 3-pointer during the 17-6 run that helped Kentucky beat its in-state archrival for the fifth time in six meetings.

The Wildcats also earned their first win against a ranked opponent in four tries this season.

Syracuse (12-0) was the third unbeaten ranked team the Wildcats (11-1) had faced this season. Villanova handed then-No. 2 Kansas its first loss of the season a month ago in the semifinals of the Battle 4 Atlantis and came back the next night and defeated No. 23 Iowa in overtime. 

Saturday's scores

• No. 2 Syracuse 78,No. 8 Villanova 62

• No. 4 Wisconsin 80, Prairie View A&M 43

• No. 5 Michigan State 101, New Orleans 48

• No. 18 Kentucky 73, No. 6 Louisville 66

• No. 9 Duke 82, Eastern Michigan 59

• No. UConn 82,E. Washington 65

• No. 17 Memphis 75,Jackson State 61

• No. 21 Colorado 84,Georgia 70

• No. 23 UMass 69, Providence 67 (OT)

• No. 24 Gonzaga 74,Santa Clara 60

• No. 25 Missouri 68, N.C. State 64

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