Terry Benedict (Andy Garcia) rounds up the eleven members of Danny Ocean’s (George Clooney) gang, and threatens them in order to force them to pay back the $160 million that they stole from his Vegas casino from their previous heist, along with $38 million in interest, within two weeks. Collectively, the group is short by nearly half, and are forced to stage another heist to collect the funds. The group opts for a European target as they are too well recognized in the United States. For their first target, recommended by an informant named Matsui (Robbie Coltrane) the team goes after the world’s oldest stock certificate issued by the Dutch East India Company in 1602. Kept in a private home in Amsterdam, the value would not be enough to settle the debt, but sufficient to extend their deadline. While the group is able to breach the security of the house, including physically lifting the house to gain the correct line of sight to deactivate the security codes, they find they have been beaten by another master thief, FranÃ§ois Toulour, also known as “The Night Fox” (Vincent Cassel). Toulour invites Danny to his home, and reveals that it was he that tipped off Terry on Danny’s casino heist, due to being upset that his mentor Gaspar LeMarc (Albert Finney) has believed Danny was the world’s best thief. Toulour challenges Danny to see who could first steal the Coronation Egg within the week, offering to pay off Terry’s debt if Danny should win.

…

LeMarc reveals in a meeting with Danny and Rusty that he had been playing a long con. LeMarc wanted to humiliate Toulour by taunting him into the bet with Danny, as well as to regain possession of the Egg that he had stolen himself long ago, only relinquishing it due to his wife’s nagging. More importantly, LeMarc wanted to be reunited with his daughter, revealed to be Lahiri, which could only be done after Danny’s crew was extradited. With Rusty’s help, Lahiri is flown in to an emotional meeting with her father. The group pays the money back to Terry, though under watch by Toulour, and then enjoy a private poker session, with Lahiri rejoining with Rusty.

The movie begins before the end of the events in The Bourne Supremacy, as Bourne, wounded by a gunshot from the Russian assassin Kirill, is still evading the Moscow police. Cornered by two officers while breaking into a medical clinic to treat his wounds, Bourne overpowers the officers, knocking one out, while holding the second at gunpoint. He leaves them alive as he escapes, saying, My argument is not with you.

Six weeks later, Simon Ross, a security correspondent for The Guardian, meets with someone in Turin, to discuss Treadstone. Bourne goes to Paris to tell Marie’s brother, Martin, of her death, then heads to London. Bourne then reads an article in The Guardian by Ross about Bourne, Treadstone, and “Operation Blackbriar.” He then arranges to meet Ross in London at the south entrance of Waterloo Station. Ross, however, is under surveillance because his use of the word “Blackbriar” in a phone call to his editor was tracked by ECHELON, alerting the CIA. CIA section chief Noah Vosen alerts his staff at the Anti-Terrorism Deep Cover in New York to find out any information on Ross, believing that Operation Blackbriar has been compromised.

After receiving a call from Bourne, Ross takes a taxi to Waterloo Station. At the station, Bourne sees CIA officers following Ross and places a prepaid mobile phone on him; through it, Bourne instructs him on how to dodge the station’s surveillance. However, Vosen orders an assassin, Paz, to kill Ross and his source. Vosen’s team identifies Bourne on a security camera and recognizes him as the original Treadstone assassin, and assumes he is Ross’s source. While Paz gets into position with a sniper rifle, Bourne tells Ross to remain hidden, but Ross panics and steps out into the open, allowing Paz to deliver a clear kill shot. In the chaos, Bourne grabs Ross’s notes, revealing his source as Neil Daniels, the Madrid CIA station chief.

…

Images of Bourne’s unmoving body floating in the river are interspersed with images of Nicky watching a news report, sometime later, noting the exposure of Blackbriar, the arrests of Hirsch and Vosen, that Ezra Kramer is the subject of a United States Senate hearing regarding his conduct, and that David Webb, alias Jason Bourne, was shot and fell into the East River but his body has not been recovered, even after a three-day search, at which point Nicky smiles. In the final moments of the film Bourne is shown swimming away in the East River.