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Thursday, April 18, 2013

Memb-PASS™ Membrane Protein Crystallography

Use less protein and accelerate the process of crystallizing membrane proteins using the new patent-pending Memb-PASS™
(Prompt Assay of Size and Stability) technology, developed by Dr.
Michael Wiener and members of his laboratory at the University of
Virginia.

Memb-PASS™ starts with a Differential Filtration Detergent Assay, a
microplate-based detergent screening method that rapidly characterizes
the stability and size of membrane proteins exchanged into a ninety-four
detergent panel provided with the Memb-PASS™ Differential Filtration Detergent Assay.
The entire assay utilizes sub-milligram quantities of membrane protein,
and requires only several hours to perform while quickly helping you
select the best detergent complex for your membrane protein! [1]

After the protein is in a suitable detergent, as determined by the Memb-PASS™ Differential Filtration Assay, the Memb-PASS™ Solubility Screen, with twenty-four conditions, is applied to determine the proper protein concentration for crystallization.

Once at proper concentration, the membrane protein can then be set up for crystallization with the Memb-PASS™ Crystallization Screen,
an innovative, ninety-six condition screen, developed for integral
membrane protein crystallization based on conditions that resulted in
successful crystallization of membrane proteins.

The Memb-PASS™ methods are specifically designed to work together to
help you significantly reduce the amount of protein, reagents and time
spent on the crystallization of membrane proteins.Flyer Memb-PASSTM

Stratech Scientific
is a distributor of high quality, competitively priced, reliable
products for research laboratories throughout the UK and Europe. Please
contact us to find out which ranges we can supply in your country.