A Research Study to Compare the Effect of Insulin Degludec and Insulin Glargine on Blood Sugar Levels in People With Type 2 Diabetes - the SWITCH PRO Study

Brief description of study

This study compares the effect on blood sugar levels of two medicines: insulin degludec and
insulin glargine in people with type 2 diabetes. Participants will be treated with insulin
degludec and insulin glargine during two different periods. Which treatment participants get
first is decided by chance. Both medicines are approved for use in humans and available on
the market. They can already be prescribed by participants' doctors. Participants will get
pre-filled insulin pens to inject these insulins with. The study will last for about 41
weeks. Participants will visit the clinic 13 times and have 27 phone calls with the study
doctor or study staff. At 12 of the clinic visits they will take blood samples. In order to
evaluate the changes in participants' blood sugar level over time, participants will be asked
to wear a small (35 millimetres (mm) x 5 mm) sensor on the back of participants' upper arm 3
times during the study. Each time participants must wear the sensor for 2 weeks. This sensor
is called FreeStyle Libre Pro. It has a very small tip which is 0.4 mm thick and is inserted
5 mm under participants' skin. Please note that participants will not be able to see the
sensor readings while wearing it. The study doctor will show participants the readings when
participants return to the clinic. Participants will be asked to fill in a diary in between
visits. Participants will have contact with the study doctor or study staff each week. This
is to adjust the dose of participants' study medicines and to ensure that participants are
well. Women cannot take part if pregnant, breast-feeding or plan to become pregnant during
the study period.