Description

Clustering miRNAs-genes pairs

Usage

1
2

Arguments

mirna_rse

SummarizedExperiment::SummarizedExperiment with miRNA
information. See details.

gene_rse

SummarizedExperiment::SummarizedExperiment with gene
information. See details.

target

Matrix with miRNAs (columns) and genes (rows)
target prediction (1 if it is a target, 0 if not).

org

AnnotationDbi::AnnotationDb obejct. For example:(org.Mm.eg.db).

summarize

Character column name in colData(rse) to use to group
samples and compare betweem miRNA/gene expression.

genename

Character keytype of the gene
names in gene_rse object.

min_cor

Numeric cutoff to consider a miRNA to regulate a target.

Details

This function will correlate miRNA and gene expression data using
a specific metadata variable to group samples and detect pattern
of expression that will be annotated with GO terms.
mirna_rse and gene_rse can be created using the following code: