Drug Research

An experimental vaccine tested in more than 7,500 people in Guinea was highly protective against Ebola in a preliminary analysis. Results from the Phase III clinical trial were reported Friday in the medical journal The Lancet. Organizations who sponsored the work, including the World Health Organization and Medecins Sans Frontiers, lauded the outcome of the work as a hopeful step in the fight against the devastating virus, which has killed more than 11,000 people in West Africa during the current outbreak and sickened more than 15,000 others. "For the first time ever, we received evidence of efficacy of a vaccine that will help [with] fighting Ebola,"...

Related "Drug Research" Articles

An experimental vaccine tested in more than 7,500 people in Guinea was highly protective against Ebola in a preliminary analysis.
Results from the Phase III clinical trial were reported Friday in the medical journal The Lancet.
...

A decade's worth of research on nonsteroidal anti-inflammatory drugs, or NSAIDs, has prompted the Food and Drug Administration to demand stiffer warnings on the labels of such prescription medications as celecoxib (marketed commercially as Celebrex)...

Jaws dropped earlier this year when Gov. Jerry Brown told the Legislature that he wanted to set aside $300 million for two years' worth of specialty drugs for Medi-Cal users, state prisoners and others covered by state health programs. Even with a...

In a bid to inject clarity into the fast-moving, high-stakes world of cancer drugs, a task force of cancer doctors announced Monday that it has devised a decision-making aid to help physicians and their patients weigh the pluses and minuses of...

There's nothing feminist about a drug that isn't very effective and can have negative side effects in the women who take it. That's something for the U.S. Food and Drug Administration to keep in mind as it reconsiders the so-called little pink pill or...

Researchers have found two drugs that saved the lives of mice infected with the deadly Ebola virus, and you may have them in your medicine cabinet already.
Zoloft, an antidepressant that has been on the market since 1991, cured 70% of mice that had the...

New research has found that a variant of a drug used to treat pulmonary arterial hypertension prompts weight-loss in obese mice. Among mice fed a high-fat diet, those who did not get the medication became obese while medicated mice did not, the same study...

Beware, weekend ragers: A new study suggests that people who use drugs only on the weekends frequently begin using them on weekdays too.
In a paper published Monday in Annals of Family Medicine, researchers report that 54% of people who...

In a group of children and young adults with the most intractable forms of epilepsy, a liquid form of marijuana called cannabidiol reduced seizures by more than 50% without causing the drug's usual "high," researchers said.
In an open-label...

Human safety tests on a promising experimental Ebola vaccine were halted temporarily when some subjects experienced arthritis or joint pain for a period of roughly a week to several months, according to researchers.
The drug, VSV-ZEBOV, is one of...

Google-backed genetic testing company 23andMe is launching its own drug development unit, betting that it can translate its database of customer DNA information into novel medicines. The Silicon Valley-based company announced Thursday that it hired...

After killing at least 9,936 people and infecting more than 24,202, the Ebola epidemic appears to be running out of steam. And for some medical researchers, this hard-won progress poses a problem.
The Ebola virus has retreated so dramatically in recent...

Amgen Inc., the Thousand Oaks biotech giant, said Sunday a new study has found its cancer drug Kyprolis is far more effective in treatment of relapsed multiple myeloma than its chief rival.
The study found that patients treated with Kyprolis after a...

ZMapp, the experimental Ebola drug that won notoriety when it was given to a handful of infected aid workers at the height of the epidemic, will now begin clinical testing in Liberian treatment centers, U.S. health authorities said.
"Although...

Girls who got vaccinated against HPV were more likely than their unvaccinated peers to become infected with a sexually transmitted disease, but the vaccine was definitely not to blame for their risky sexual behavior, according to a new study of more...

Can measles really kill you? Is the vaccine more dangerous than the disease?
People seeking answers to questions like these often search for them online. And when they do, they can be strongly influenced by the information they find there – even when...

How do you convert a simple saline solution into a useful treatment for people with Parkinson’s disease? Tell them it’s a drug that costs $100 per dose. And if you want to make it even more effective, tell them it costs $1,500 instead.
That’s what...

The first 300 doses of an experimental Ebola vaccine were headed for Liberia on Friday, but health authorities say the West African nation may already have turned the corner on slowing the outbreak of the deadly disease.
Although the vaccine was...

A monthly injection of an experimental anti-retroviral drug protected female monkeys from vaginal infection by a simian form HIV, according to two new studies.
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Taking the cancer drug tamoxifen for five years drives down the incidence of breast cancer in women at high risk for the disease by close to 30%, researchers have found. And the medication's protective effects against breast cancer appear to last,...