Pulmonary Laboratories & Research Groups

Pulmonary Labs A-J

Our lab focuses on the Pathogenesis of airway diseases with a focus on asthma and asthma severity, the role of chitinases in the development and severity of asthma, and expression and genotype-phenotype relationships of novel inflammatory molecules. Read More...

His laboratory focuses on two main research programs. (1) Studying the effects of cigarette smoke (CS) exposure in the pathogenesis of airway and lung diseases such as chronic obstructive pulmonary disease (COPD) using preclinical genetic mouse models and human biosamples. (2) Studying novel immune regulators in the lung during respiratory infections. Read More...

Gomez Laboratory examines the role of secondhand cigarette smoke in the transcriptome of the asthmatic airway. Computational biology of the lung. Translational informatics of lung disease. Read More...

Pulmonary Labs K-Z

Dr Kaminski’s research is currently focused on improving our understanding and treatment of chronic lung diseases such as Idiopathic Pulmonary Fibrosis (IPF), a chronic lung disease characterized by progressive scarring of the lungs, as well as COPD, Sarcoidosis and Asthma. Read More...

Kang laboratory is focusing on the role(s) of mitochondrial dysfunction and immune dysregulation in the setting of smoking exposure such as those seen in patients with COPD and CS- and virus-associated disorders. Read More...

Paty Lee Laboratory investigates mechanisms of lung injury and cytoprotection during oxidant stress. Specifically, we have focused on the lung endothelium as a central mediator of lung injury and repair responses. Read More...

Mannam laboratory is interested in determining the role of innate immune signaling pathways in sepsis and lung injury. Specifically, we are investigating the role of MKK3, a mitogen-activated protein kinase-signaling molecule, in the regulation of endothelial function and septic responses. Read More...

Research Groups

The MICU Database and Biorepository was established in 2012 and currently is enrolling patients who are admitted to the medical ICU who are age 18 or older with ARDS, ALI, sepsis or other critical illness. Read More...

The TIP Research Group under the direction of Jonathan Puchalski, MD has established a database of all patients undergoing thoracic interventional procedures at Yale-New Haven Hospital. These procedures include diagnostic and therapeutic bronchoscopy, pleural procedures including pleurx catheter placement, pleuroscopy and thoracentesis as well as percutanous tracheostomies. Read More...

We have examined the feasibility of using both polysomnography and actigraphy for measuring sleep in critically ill patients in our medical ICU. We are also examining the impact of noise, light and staff interruptions to sleep in our ICU. Read More...

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