Glasgow, Scotland, UK—8 November 2017—ISPOR, the professional society for health economics and outcomes research (HEOR), held several sessions on the topic of real-world evidence at its 20th Annual European Congress currently being held 4-8 November 2017 in Glasgow, Scotland, UK.

On 6 November a workshop was held entitled, “Generating Real-World Evidence for Real-World Decisions: Application of Advanced Methods” [W6]. Discussion leaders included, Mark Sculpher, PhD, University of York, York, UK; Richard Grieve, PhD, London School of Hygiene and Tropical Medicine, London, UK; Anirban Basu, PhD, University of Washington, Seattle, WA, USA; and Stephen O’Neill, MEconSc, PhD, National University of Ireland, Galway, Galway, Ireland. Many global health technology assessment (HTA) agencies are now requiring evidence on effectiveness and cost-effectiveness of new health care interventions on real-world populations. During this workshop, speakers explored how understanding the power and limitations of advanced statistical and econometrics methods can help generate real-world evidence and build confidence of HTA agencies in these types of results.

The Use of Real-World Evidence in Assessing Cardiovascular Treatments:

On 7 November a workshop, “Getting to the Heart of the Matter: Real-World Evidence as an Indispensable Source for the Ongoing Assessment of Cardiovascular Treatments” [W12], was held. Discussion leaders included Kathleen E. Hughes, MBA, Avalere Health LLC, Washington, DC, USA; Colin Berry, FRCP, PhD, University of Glasgow, Glasgow, UK; Pall Jonsson, PhD, National Institute for Health and Care Excellence, Manchester, UK; and Yi Qian, PhD, Amgen Inc, Thousand Oaks, CA, USA. This session featured panelists describing how their organizations use real-world evidence to augment data from randomized controlled trials to evaluate the clinical effectiveness, cost effectiveness, and patient-reported outcomes of cardiovascular therapies. Panelists represented the perspective of clinicians, manufacturers, health technology assessment bodies, and consultants in discussing the use of real-world evidence in the assessment of cardiovascular treatments.

On 8 November an issue panel was held, “Adaptive Pathways for Transformative Medicinal Products: A New Paradigm with the Enhanced Application of Real-World Evidence?” [IP21]. The session was moderated by David Schwicker, MA, ORPHA Strategy Consulting, Basel, Switzerland with speakers Nicola Bedlington, European Patients’ Forum and The Patient Access Partnership PACT, Brussels, Belgium; Ad Schuurman, MA, National Health Care Institute, Dieman, The Netherlands; and Rob Thwaites, MA, MCom, Takeda, London, UK. The panel debated the issues from a variety of perspectives, including how health care stakeholders can jointly improve the process of adaptive pathways, the role real-world evidence plays to support conditional authorization and market access, the current limitations in implementing value-based managed entry schemes in Europe and potential solutions, and how the patient community can enhance early access initiatives as mediators and decision makers.

Additional information on the ISPOR 20th Annual European Congress can be found here. Released presentations from the congress can be found here. Interested parties can follow news and developments from the congress on social media using the hashtag #ISPORGlasgow.

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