Antibiotic

Cefo Plus 100 tab

Description

CEFO PLUS is a combination of Cefixime (3rd generation cephalosporin) & Ofloxacin (fluoroquinolone) for the treatment of Typhoid fever, Urinary tract infection & Respiratory tract infection. Cefixime kills bacteria by inhibiting bacterial cell wall synthesis & ofloxacin kills by affecting bacterial DNA gyrase. As both acts on different target sites provide synergistic effect against most of pathogens also both Cefixime & Ofloxacin have been recommended by the WHO for the treatment of Typhoid.

CEFO PLUS is a combination of Cefixime (3rd generation cephalosporin) & Ofloxacin (fluoroquinolone) for the treatment of Typhoid fever, Urinary tract infection & Respiratory tract infection. Cefixime kills bacteria by inhibiting bacterial cell wall synthesis & ofloxacin kills by affecting bacterial DNA gyrase. As both acts on different target sites provide synergistic effect against most of pathogens also both Cefixime & Ofloxacin have been recommended by the WHO for the treatment of Typhoid.

CEFO PLUS is a combination of Cefixime (3rd generation cephalosporin) & Ofloxacin (fluoroquinolone) for the treatment of Typhoid fever, Urinary tract infection & Respiratory tract infection. Cefixime kills bacteria by inhibiting bacterial cell wall synthesis & ofloxacin kills by affecting bacterial DNA gyrase. As both acts on different target sites provide synergistic effect against most of pathogens also both Cefixime & Ofloxacin have been recommended by the WHO for the treatment of Typhoid.

Maximizing bacterial eradication is a key goal in the selection of appropriate antimicrobial therapy in respiratory tract infection.
By using only amoxicillin it is not possible to completely eradicate the micro organisms. Because some of the bacterium develops resistance by secreting an enzyme known as β-lactamase, which destroys the beta lactam ring of amoxicillin & thus the bacteria is not killed.
Clavulanic acid is a beta-lactamase inhibitor which when combined with amoxicillin extends the antibacterial activity of amoxicillin to beta-lactamase-producing strains, which are otherwise resistant.
Clavulanic acid is adequately absorbed after oral administration and its basic pharmacokinetic characteristics are similar to those of amoxicillin.