CLINICAL TRIAL INTERPRETATION IN RHEUMATOID ARTHRITIS:

PRINCIPLES AND CHALLENGES

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This module covers the principles and challenges of interpreting clinical trials in rheumatoid arthritis (RA) and lays the foundation for future self-study. RA trial design can be highly complex, with numerous elements such as end-point selection and inclusion/exclusion criteria.

This presentation:

Outlines the considerations that affect the design and interpretation of RA clinical trials

Provides rheumatology fellows with tools to apply data to clinical decision making

Highlights the importance of understanding risks and benefits of treatments

Faculty

PAUL JOHN DEMARCO, MD

Rheumatologist
Arthritis and Rheumatism Associates, PCClinical Associate Professor of Medicine
Georgetown University School of Medicine

Dr DeMarco is a respected thought leader of the rheumatology community, with more than 20 years of rheumatology experience and 20 peer-reviewed papers to his name. He currently serves as a rheumatologist at Arthritis and Rheumatism Associates, PC, and as a Clinical Associate Professor of Medicine at Georgetown University School of Medicine. He is a member of the Ultrasound School of North American Rheumatologists (USSONAR), the American Institute of Ultrasound in Medicine, and the American Medical Association, and a fellow of the American College of Rheumatology and the American College of Physicians.

Dr DeMarco received his undergraduate and medical degrees from Georgetown University. He completed his internship, GMO assignment, and residency during his service in the US Navy, and his fellowship in rheumatology at the Scripps Clinic and Research Foundation in La Jolla.

PHILIP J. MEASE, MD

Clinical Professor of Medicine
University of Washington School of MedicineDirector
Rheumatology Clinical Research Division,
Swedish Medical Center

Dr Mease is clinical professor of medicine at the University of Washington School of Medicine and director of the rheumatology clinical research division at Swedish Medical Center in Seattle, Washington.

Dr Mease received his undergraduate and medical degrees from Stanford University in Stanford, California. He completed his residency in internal medicine and fellowship in rheumatology at the University of Washington. He is a leading researcher and educator on disease state and treatment of rheumatic disorders.

His research focuses on emerging therapeutics and outcome measures for clinical trials. He has served as principal or coprincipal investigator on numerous clinical trials, including recent studies on therapies for psoriatic arthritis, ankylosing spondylitis, rheumatoid arthritis, fibromyalgia, and lupus, and has authored over 300 articles, numerous abstracts, and book chapters on these and related subjects.

As former president of the Philadelphia Rheumatism Society and director of Rheumatology Education at Abington Memorial Hospital, Dr Pritchard has long established himself as a respected leader in rheumatology. He serves as an associate member of the American College of Physicians and a fellow of the American College of Rheumatology. Dr Pritchard teaches at Abington Memorial Hospital, Temple University Hospital, and Drexel University, and he is a member of the attending staff at Doylestown Hospital.

Dr Pritchard completed his undergraduate degree at Lafayette College, his medical doctorate at George Washington University Medical School, his residency at Washington Hospital Center, and his fellowship in rheumatology at Temple University.