I stopped in here with my girlfriend while doing a cross-border beer run in Port Huron. Quay Street brewpub, Wolverine Market, and Ryanís Party Store are all within a few minutes of each other, so we made a day trip of it and visited all three places.
Ryanís has roughly four times the selection of Wolverine but you have to watch for beers that are out of code and the prices are slightly higher. As examples, the sixers of Stone Pale Ale were best before last month, several Rogue bottles were produced in 2008 and had layers of dust on them, and various bombers were in the double digits price wise. Hence I focused on the fresh and reasonably priced stuff.
Ended up grabbing Sierra Nevada Celebration, Tumbler & Northern Hemisphere, Moylanís IPA, DIPA & Impy Stout, Southern Tier Heavy Weizen & Mokah Stout, a 750 of Saison Dupont, Victory Hop Devil & Storm King Stout, New Holland The Poet, Avery Collaboration & Czar, Lagunitas Maximus & Little Sumpiní Ale, North Coast Old Stock Ale & Old Rasputin, and others that I canít remember. A case and a half of these bottles, several of them bombers, ran me $150 - pretty expensive though not bad considering the caliber of beers.
The staff werenít nearly as friendly as the Wolverine folks but they did give us some empty six packs and a couple 2-4 boxes to carry the beers with. The owner explained to me that they donít break apart six packs because nobody would want the leftover brews. As a result I wasnít able to buy a few bottles that I snagged from sixers but I still managed to get a good haul of decently fresh, world class beer.
Overall, this store has the largest variety in town and itís a very convenient border stop for beer-deprived Ontarians. I will be back for many more beer hauls in the future.

Ryanís doesnít look like much when you walk in but the back of the store is a little piece of beer heaven. There is one long shelf and wall of refrigerators crammed with hundreds of different beers. Lots of American craft breweries represented including Stone, Bellís, Arrogant Bastard, Rogue, and New Holland, supplemented with a decent selection of Belgians (Rochefort, Chimay etc.) and other European brews. A great place to pick up a great beer and close to the bridge for Canadians searching for brews they canít get at home.

Not much for ambiance, the place looks like a divvy convenience store. But the staff is super friendly and went out of their way to make us happy. Brian, the owner, cleared out a shopping cart for us and answered a whole ton of questions and made some pretty good suggestions too. Even through in a few freebies with his expert advice. Call ahead for any requests, heís more then willing to take custom orders. They have some decent selection, but not great.. that being said, custom order and youíll get what you want if Brian can get it for ya!