Welcome to Medical News Today

Healthline Media, Inc. would like to process and share personal data (e.g., mobile ad id) and data about your use of our site (e.g., content interests) with our third party partners (see a current list) using cookies and similar automatic collection tools in order to a) personalize content and/or offers on our site or other sites, b) communicate with you upon request, and/or c) for additional reasons upon notice and, when applicable, with your consent.

Healthline Media, Inc. is based in and operates this site from the United States. Any data you provide will be primarily stored and processed in the United States, pursuant to the laws of the United States, which may provide lesser privacy protections than European Economic Area countries.

By clicking “accept” below, you acknowledge and grant your consent for these activities unless and until you withdraw your consent using our rights request form. Learn more in our Privacy Policy.

Please accept our privacy terms

We use cookies and similar technologies to improve your browsing experience, personalize content and offers, show targeted ads, analyze traffic, and better understand you. We may share your information with third-party partners for marketing purposes. To learn more and make choices about data use, visit our Advertising Policy and Privacy Policy. By clicking “Accept and Continue” below, (1) you consent to these activities unless and until you withdraw your consent using our rights request form, and (2) you consent to allow your data to be transferred, processed, and stored in the United States.

Get the MNT newsletter

Email an article

You have chosen to share the following article:

How elderberries can help you fight the flu

To proceed, simply complete the form below, and a link to the article will be sent by email on your behalf.Note: Please don't include any URLs in your comments, as they will be removed upon submission.

We do not store details you enter into this form. Please see our privacy policy for more information.

Message sent successfully

Assessing The Effects Of Environmental And Genetic Factors On Children's Health

Published
Friday 5 October 2007 Published Fri 5 Oct 2007

Adapted Media Release

The UCLA Center for Healthier Children, Families and Communities has been selected as one of 22 new study centers for the National Children's Study, a nationwide project designed to assess the effects of environmental and genetic factors on children's health in the United States. The study center will manage local participant recruitment and data collection for the largest study of child health ever conducted in the United States.

The National Children's Study is a collaborative effort between the U.S. Environmental Protection Agency and the Department of Health and Human Services (including the National Institute of Child Health and Human Development, the National Institute of Environmental Health Sciences at the National Institutes of Health, and the Centers for Disease Control and Prevention).

"This study is big science and it will be one of the most important generators of new knowledge on child and adult health and development ever attempted," said principal investigator Dr. Neal Halfon, professor of pediatrics, public health and public policy at UCLA and director of the UCLA Center for Healthier Children, Families and Communities. "It will help children across the U.S. and shape child health guidance, interventions and policy for generations to come."

The National Children's Study will eventually follow a representative sample of 100,000 children from before birth to age 21, seeking information that will help prevent and treat some of the nation's most pressing health problems, including autism, birth defects, diabetes, heart disease and obesity. To better understand the impact of exposures on the developing fetus, infant and child, the study will recruit pregnant women, as well as women who are likely to become pregnant, in order assess environmental health influence during the pre-pregnancy and prenatal period.

The UCLA Center for Healthier Children, Families and Communities is an internationlly distiguished leader in child health research and policy. The grant will be housed within the division of child health policy and community pediatrics at Mattel Children's Hospital UCLA. The UCLA-based team of scientific investigators will be joined by collaborating investigators from Cedars-Sinai Medical Center, the University of Southern California, Charles R. Drew University of Medicine and Science, the Los Angeles Department of Public Health, First 5 Los Angeles County, the Ventura County Public Health Department, First 5 Ventura County, the Research Triangle Institute and the Rand Corp.

The NIH has approved $47.9 million to launch the study and enroll 5,000 children in Los Angeles and Ventura counties, in waves of 1,000. The first installment of funding, $14.7 million, will cover the establishment of the study center, a 22-month planning phase and a 38-month enrollment of the first 1,000 children. Actual data collection for this first wave is scheduled to begin in the late summer of 2009.

The National Children's Study is on a par with other major scientific projects like the Human Genome Project and the Women's Health Study, and the NIH estimates that the study's price tag the over the next 30 years will reach the $3 billion mark. At this point, Congress has yet to authorize the full amount needed for the study and has chosen to provide incremental funding.

"While $3 billion is a lot of money, over this 30-year period it will represent less than 1 percent of the NIH annual research budget," said Dr. Michael Lu, associate professor of obstetrics and gynecology and public health at UCLA and a lead investigator for the study.

Supporters of the study further argue that six of the health conditions the study will target -- asthma, obesity, schizophrenia, autism, learning disabilities and injuries -- currently cost the nation more than $600 billion dollars a year. If knowledge resulting from the study was to reduce expenditures for these conditions by 1 percent, the study would pay for itself many times over.

The University of California is well-represented in the study and will contribute much-needed expertise. In addition to UCLA, other new study centers were awarded to UC Irvine (for San Diego and San Bernardino counties, to go along with the existing Vanguard Center for Orange County) and UC Davis (for Sacramento and San Mateo counties). With the collaboration between the lead UC centers and additional sites, it is projected that more than 10,000 Californians will be enrolled in the study.

When fully funded, the study will be conducted in 105 study locations across the United States. A national probability sample was used to select the counties in the study, which will be representative of the U.S. population as a whole.

The National Children's Study began in response to the Children's Health Act of 2000, when Congress directed the National Institute of Child Health and Human Development and other federal agencies to undertake a long-term national study of children's health and development in relation to environmental exposures. A group of more than 2,000 scientists from across the U.S. have been designing and planning the study for the past six years.

The announcement of the new study centers follows earlier study milestones, including the 2004 announcement of the 105 study locations and the establishment of the seven Vanguard centers in 2005.

"We urge the public to watch out for future announcements about the National Children's Study and opportunities to enroll children from Los Angles County starting in 2009 and Ventura County at a later date," said co-principal investigator, Dr. Calvin Hobel, who is vice chair of the department of obstetrics and gynecology at Cedars-Sinai Medical Center and holds the Miriam Jacobs Chair in Maternal-Fetal Medicine. "This is a historic and once-in-a lifetime opportunity that will advance our understanding of the causes and prevention of some of the common and rare disorders of childhood."

2019 Healthline Media UK Ltd. All rights reserved. MNT is the registered trade mark of Healthline Media. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional.