GlycoMark®

The GlycoMark® test is a surrogate marker to detect frequent and high glycemic excursions in diabetic patients and measures blood levels of 1,5-anhydroglucitol (1,5-AG), a glucose-like sugar found in food. When blood glucose levels are well controlled, most circulating 1,5-AG is reabsorbed in the kidneys instead of being excreted in the urine. In healthy individuals, circulating levels of 1,5-AG are high, with median values exceeding 20 μg/mL. However, when blood glucose levels are high, 1,5-AG reabsorption is blocked and a majority is excreted in the urine.