Micro-Media® L Series Filter Sheets

Micro-Media FilterL Series sheets can be formulated using high purity cellulose to reduce the occurrence of false positives caused by 1,3 beta D glucans in cellulose pulp.

Micro-Media L Series filter sheets are specifically designed for use in applications where proteins are present, such as blood fractionation and recombinant DNA derived products. These particular types of applications demand specific controls on pyrogens and extractables. Physical attributes, unique to such applications can lower the surface tension of the media and cause them to release extractables. This can cause problems with the LAL testing used both in process and as a final release. These extractables can cause “false positives” by reacting with a Factor G in the LAL reagent and cellulose components.

A particular source of extractables is 1,3 ß D-glucan contamination in the cellulose. Cellulose is a major component of depth filter products. The level of reactivity depends upon the amount of 1,3 ß D-glucans released during manufacturing of the filter media and the amount of Factor G present in the LAL reagent, which varies by manufacturer.

Utilizing a unique process, ErtelAlsop minimizes 1,3 ß D-glucan levels in cellulose pulp prior to manufacturing the filter media. This minimizes the effects of 1,3 ß D-glucans and allows for validation of the LAL test on the product.

BenefitsGrades & RetentionsApplicationsCompositionDownloads

Extemely low 1,3 B D-glucan content

Lower frequency of false positive LAL tests

* Table is for Reference Only

Processes with endotoxin concentration issues, or when clear detection of one endotoxin over the other is difficult

The Format to Fit Your Needs

As with all ErtelAlsop presses, filter media is available for any application and/or operating condition, and is chosen based on your specific operating conditions. ErtelAlsop offers the widest varieties of filter media and construction techniques to provide good particle retention, clear filtrate, high flow rates, and dry filter cakes.

Made in the USA

ErtelAlsop is an innovator in the manufacturing of depth filter media and machinery for liquid filtration since the 1920’s, and is your one source for all depth filtration and liquid processing products. ErtelAlsop’s customer base is filled with clients who have been buying from us for over 80 years.