In this webinar, neuroscientist Seong-Gi Kim and market product manager Tim Wokrina from Bruker BioSpin will discuss how CEST imaging, combined with blood oxygen level dependent (BOLD) fMRI of the rodent brain at ultra-high field MRI is leading to significantly improved sensitivity and specificity, enabling new insights into the brain function. This webinar will appeal to MRI users and those in the field of neuroscience. View the recording or Download the slides

Siderophores, iron-chelating ligands produced by microorganisms, have demonstrated potential in the field of medical imaging. In this webinar, preclinical imaging specialist from Bruker, Todd Sasser, will introduce Zbynek Novy and Milos Petrik (Institute of Molecular and Translational Medicine, Palacky University) who have used labeled siderophores in the nuclear and optical imaging of both infection and cancer. The discussion will interest anyone working in clinical or nuclear medicine departments and hospital-based research. View the recording or Download the slides

Getting a good microCT image of your animal’s bone, in vivo or ex vivo, is just the start. To realize the goals of your preclinical study, quantitative outcomes are needed. From two decades of experience, Bruker microCT brings a universal microCT analysis pipeline – a transparent flexible system and workflow that can deliver your needed quantitative outcomes, for every disease model. View the recording or Download the slides

In ovo MRI is a preclinical imaging technique in oncology research that involves the study of chicken egg embryos and a structure called the chorioallantoic membrane (CAM). In this webinar, medical physicist Prof. Volker Rasche (University Hospital Ulm, Germany) and Bruker’s MRI product specialist Dr. Thomas Basse, will discuss how in ovo MRI can be used to non-invasively monitor contrast agent-labelled compounds in CAM models of transplanted tumor cells. This will interest anybody using MR systems for oncology research, ranging from technicians through to bio-engineers, biological researchers and physicians. View the recording or Download the slides

June 8, 2017

In Vivo Tumor Progression Studies: The Relative Strengths of available Imaging Modalities and Reporter Constructs

Combining preclinical in vivo imaging modalities offers the opportunity to synergize the strengths of each in one experiment. In this webinar, Dr. Kah-Wye Peng, Chief Operating Officer at Imanis Life Sciences, will outline the range of products and reagents offered by the company for use in optical imaging. Co-presenter Dr. Andrew Van Praagh, Field Applications Scientist, from Bruker BioSpin, will demonstrate some specific examples of preclinical research drawing together the technology from both companies, including Bruker’s multimodal Xtreme II imaging system. View the recording or Download the slides

Small animal pre-clinical imaging is a vital tool in the field of biomedical research, allowing the study of biological processes and potential diagnostic or therapeutic agents in living animals. Today, pre-clinical imaging often involves multimodal systems that combine anatomical techniques such as magnetic resonance imaging (MRI) with visualization techniques such as positron emission tomography (PET). View the recording or Download the slides

Chemical Exchange Saturation Transfer (CEST) imaging has emerged over the past decade as a new and innovative MRI contrast method, specifically designed for molecular imaging. This original approach can detect small amounts of contrast agent through saturation of fast exchanging protons, allowing for a larger number of imaging schemes and techniques. View the recording or Download the slides

In vivo imaging is at the heart of preclinical research into cancer biology and treatment, with advances in technology delivering tools that are ever more powerful, accurate and easy-to-use. In this webinar, you will hear about one lab’s experience of integrating one such technology – Bruker’s preclinical PET system – into a hospital-based small-animal imaging lab, and how it has assisted their paradigm-shifting research into cancer cell biology. View the recording or Download the slides

Small animal imaging can provide invaluable insights into mechanisms of disease, as well as the effects of candidate therapeutics in preclinical settings. MicroCT, a tool for preclinical imaging, allows the same technology used in a medical CT scanner to be applied on a microscopic level, meaning detailed “slices” can be taken non-destructively through samples and living animal models. View the recording or Download the slides

Webinar

Content

October 25, 2016

Utilities and Methods for In Vivo Bioluminescent Imaging in a CRO Laboratory

Easy control for enjoyable experience: New Skyscan 1276, High resolution In Vivo micro tomography

Presenter: Kjell Laperre - Applications Manager, Bruker microCT

Bruker’s new SkyScan 1276 in vivo microCT combines high-resolution, speed, accessibility and innovation to uphold improved in vivo scanning of small laboratory animals and biological samples in preclinical studies. View the recording or Download the slides

September 1, 2016

Molecular Imaging Using CEST MRI

Presenter: Professor Silvio Aime - Professor of General and Inorganic Chemistry at the Department of Molecular Biotechnologies and Health Sciences, Head of the Center of Excellence on Molecular Imaging of the University of Torino, Italy

In the last years in vivo optical imaging has become an integral part in preclinical science and shows a broad spectrum of possible applications: from the development and evaluation of new contrast agents for clinical application or pharmacological studies to the examination of complex physiological and patho-physiological processes. Thus, in vivo optical imaging has the ability to confirm and to advance in vitro results. View the recording or Download the slides

July 21, 2016

The Revolution in Preclinical PET - Continuous Crystal and Smart Electronics to Achieve Full Field Accuracy

In vivo imaging technologies are at the core of advanced preclinical research. Understanding dynamic biological processes, gene expression, enzyme and protein activity, progression and treatment of diseases, biodistribution, pharmacodynamics or pharmacokinetics of new drugs in repeatable, longitudinal studies is building a better future for everyone. View the recording or Download the slides

With five imaging modalities in one instrument, researchers can leverage the individual strength of each while combining them to obtain both anatomical and functional information. Learn more in this free, informative webinar. View the recording or Download the slides

Dr Bernard Siow and his colleagues from the Center for Advanced Biomedical Imaging at University College London will elaborate on the research they are conducting using the ICON, including monitoring of tumors, characterizing the phenotype of animals, following brain damage in stroke models and measuring edema after heart infarct. View the recording or Download the slides

Sensitive in vivo luminescent imaging systems may be leveraged not only for traditional bioluminescent imaging applications, but also for detection of PET radionuclide Cherenkov radiation. During this webinar we will overview the multimodal capabilities of the In-Vivo Xtreme, highlighting the application potential for DRI.View the recording or Download the slides

Historically used to image bone, microCT has become a valuable tool for soft-tissue applications thanks to the development of preclinical contrast agents. Learn how this non-destructive technology can be applied to a wide range of applications, including lung imaging, cardiovasculature studies and oncology research.View the recording or Download the slides

Professor Niendorf will demonstrate in this 30 min Webinar that the use of a cryogenically cooled RF coil presents valuable means to enhance the capabilities of cardiac and brain MRI in mice. The MRI CryoProbe affords significant signal-to-noise (SNR) gains of 3.0 to 5.0 versus conventional room temperature coils and hence enables an enhanced spatio-temporal resolution to study cardiac morphology and function, as well as offering sufficient detail to follow neuroinflammatory processes in the brain.View the recording or Download the slides

March 18, 2014

Glioblastome Multiforme - Bridging the Gap between Diagnostics and Treatment

Glioblastome multiforme is the most common form of brain cancer and diagnosed patients have a life expectancy of less than two years. In spite of the fact that its diagnosis is very good, an appropriate treatment remains elusive. The use of animal models can help to provide a basis for treatment testing, but it is vital that they mirror the clinical cases as closely as possible. Once the models are established treatment research can begin. Oncology labs are bringing the power of Preclinical MRI to bear in the goal to bridge the still significant gap between diagnostics and treatment. Discover how researchers are bringing brain tumor treatment ever closer. View the recording or Download the slides

Following the huge upsurge in interest in bringing imaging to new and wider areas of research, Bruker is not only seeking to support new multimodality approaches through its instrument portfolio, but has also completely redesigned its preclinical MRI software to offer enhanced productivity and multi-platform capability. A newly revised intuitive workflow and easier parameter handling means ParaVision’s new benefits can be enjoyed by both the accomplished expert and routine users. You will learn the most advanced method development options.View the recording or Download the slides