Our GeneSavvy Reports are designed for functional medicine practitioners that are determined to find answers for their patients.

The GeneSavvy Keys ToActionable Genetic Reports

Our reports were built with functional medicine practitioners in mind, so the results and terminology used in our reports will be easy to understand and work with in functional clinical settings.

PERSONALIZED RESULTS

We use genetics to develop more personalized approaches to functional medicine. That’s why we prioritize the more rare and uncommon variants found in each gene, those are the genetic markers that make people different!

ACTIONABLE GENETIC ASSOCIATIONS

We work hard to include clinically actionable associations for the results outlined in our reports. Those actionable associations can include further lab testing, treatments, clinical action bullet points, and environmental interactions related to the genes and gene networks listed.

BATTLE TESTED

All of our genetic reports were first built as extremely custom tools for real life cases where we were contracted to help practitioners think outside the box and find the missing pieces keeping their patients from making progress. The custom reports built to help those patients and practitioners make progress are then turned into the reports we offer here.

If you need a custom genetic tool or report built to help assist in a complex health case, please contact us at [email protected]

What Information Is Available In Our GeneSavvy Reports?

All of GeneSavvy’s test panels are designed to provide deep analysis of the specific genes they are looking at. This provides the biggest picture possible on the most relevant genes to your current health concerns.

With the PowerXomeGS Whole-Exome panel, we provide deep coverage on all genes shown to be relevant in ALL health concerns so if something pops up down the road, we will already have the clinically relevant genetic data for you to take action in the most efficient way without the need for further genetic testing.

GeneSavvy Genetic Networks

We build comprehensive genetic networks surrounding diseases, biological functions, and more to help identify possible targets for clinical action. We look to identify rare, high impact gene variants that are shared across multiple networks as possible root causes behind complex health conditions.

High Impact Rare Variants

There are no current FDA approved treatments for Chronic Fatigue Syndrome or Myalgic Encephalomyelitis. The CDC also acknowledges that the treatment of these diseases is extremely complex due to the unknown information about what causes the symptoms. These factors have created the need for extremely personalized treatment approaches that change often based on current and most prevalent symptoms.

When it comes to looking for the cause of symptoms to create extremely personalized treatments, genetics are one of the most valuable tools you can use. Looking at genetics can help health professionals find abnormal gene products, biological pathway inefficiencies, and gene/environment actions that can greatly affect the severity of associated symptoms. These factors create a powerful tool for personalized treatments related to Chronic Fatigue and will also hugely contribute to our knowledge of the cause of these complex diseases and assist in diagnosis protocols.

( Example Actions From Our Craniocervical Instability (CCI) Report )

Actionable Associations

We build comprehensive genetic networks surrounding diseases, biological functions, and more to help identify possible targets for clinical action. We look to identify rare, high impact gene variants that are shared across multiple networks as possible root causes behind complex health conditions.

The GeneSavvy Bio-Informatic Process

Annotation Databases Used

We use a large amount of 3rd party databases along with our own databases to create useful data related to your variants! Here are some of the data sources you will find in our reports:

GeneFTX

RefSeq

ENSEMBL

dbSNP

ClinVar

OMIM

GWAS

MitoMap

SIFT

PolyPhen2

LRT

MutationTaster

FATHMM

InterVar

CADD

GERP++

ExAC

gnomAD

1000 Genome Project

NCBI

Plus More!

Results You Can Trust

Exome Region Coverage: 50x

Mitochondrial Genome coverage: 500x

GeneSavvy processes your genetic information using state-of-the-art lab equipment and advanced management protocols to ensure the best and most reliable results we can deliver. Our GeneSavvy Genetic testing sequences your genetic exome regions with an average coverage of 50x and your whole mitochondrial genome with an average coverage of 500x.

At GeneSavvy we have developed several proprietary tools that are incorporated in this process to create our full TriarKK™ bioinformatic pipeline.

Treatment Modalities Combined

At GeneSavvy our advisors, panel curators, and treatment option experts have come together from all different modalities of the health industry to provide well rounded treatment options without bias towards one or the other, its all about providing the best action for you. Specialties include: