Histopathologic Assessment

It would be ideal to remove a malignant lesion in one piece, so allowing an adequate histologic evaluation. However, in many instances piecemeal resection is unavoidable. The specimens should be immediately stretched and fixed on a rubber plate, then placed in 10% formalin solution. The surface of the lesion should be reconstructed for the pathologist. If the resected fragments are placed in a tube with formalin, without being fixed, they will retract, and the histologic analysis will be inaccurate.

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.