Anti Sickness Medication

Can I have your opinions on anti sickness tablets ladies. What works for you?

Do you take them first thing in the morning? With food or without?

I've been struggling for weeks, not able to keep food or fluid down.. finally been to GP who has prescribed metoclopramide. I've only taken the one so far and it helped with the nausea and sickness but I had horrendous stomach cramps.

Comments (16)

I take cyclazine, metochlopramide and ondansatron x3 a day. I think everyone has success with different meds but here's my experience/knowledge (from two pregnancies).

Usually cyclazine is the first one doctors try out. It's a popular anti sickness pill. Then if that doesn't work, they add metochl. My friend who is a doctor (not a gp) said that with regards to metchlo it's main function is to speed up your digestion so that if you are sick you don't lose your food. If these 2 aren't helping then they bring out the big guns and give you ondansatron (also known as zofran). This is a very good anti sickness pill that usually works for people if nothing else has. It's very expensive so doctors are often reluctant to prescribe it (and is usually reserved for chemo patients). It was only when I added ondansatron to my cocktail of pills did I finally manage to keep food and drink down.

So I take them x3 a day and take them about 20-25 mins apart... starting about 90 mins before each meal (so my last pill is taken about 20mins before I actually eat).

I was on ondansetron with ds (dear son) and now taking it again, hospital didn't have much choice due to meds I'm on for epilepsy they had option of that or cyclizine, as soon as the cyclizine hit my blood stream it caused me to have a seizure so that as they say was that, the first gp I saw though wasn't very enthusiastic about giving many because of quantity, i ended up having to beg for more on Christmas eve, the gp who prescribed it then just went on the hospitals instruction, i know from reading many other people's experiences on this board that I'm very lucky to have such an understanding gp (with this pregnancy they've put it straight on repeat)

I try and take ondansetron with food if possible, even if I'm feeling 'ok' I'll take it when I can take it again as once the nausea takes hold getting it down is a struggle, for the sickness it's being effective, the nausea is on and off but can mainly deal with that one, just hoping it won't last my entire pregnancy this time!

Thank you so much for your replies ladies.
I'm only 8 weeks. Have been sick constantly for 3 weeks. Not keeping fluid down.
Too be honest the metoclopramide is doing nothing today.
I'm very tired which I don't think is helping.
I've heard a lot about ondansetron but my drs will not prescribe it! He didn't mention the cost, he just said it's not as safe as others.
Thinking of asking to change to cyclazine or just persevering a little longer.
Can't take much more!

Had sickness with my first but it's certainly a different ball game doing it with a toddler

Thank you so much for your replies ladies.
I'm only 8 weeks. Have been s...

Posted
21/09/2017

Thank you so much for your replies ladies.
I'm only 8 weeks. Have been sick constantly for 3 weeks. Not keeping fluid down.
Too be honest the metoclopramide is doing nothing today.
I'm very tired which I don't think is helping.
I've heard a lot about ondansetron but my drs will not prescribe it! He didn't mention the cost, he just said it's not as safe as others.
Thinking of asking to change to cyclazine or just persevering a little longer.
Can't take much more!
Had sickness with my first but it's certainly a different ball game doing it with a toddler

Try cyclazine... don't persevere. I did that with 1st pregnancy and ended up in hospital for 2 weeks. I'd also suggest getting smthg called Ketostix that you can buy from chemist. They're urine dip sticks that check if u have ketones in your urine. If you do then it might be worth going to ur a&e so they can put u in some fluids. Speak to another gp if u must... they will never say it's cos of cost xx

Hello im new to the board. On my second pregnancy and had hyperemesis also with my first. The dr gave me metachlopromide too and i had the same thing with stomach cramps. Im now on cyclizine. So far i feel okay but tired but could be because my lo kept waking me up last night too. I still need to eat allll the time or the nausea comes back. I wish i remembered the name of the medication that worked for me last time but was at a different drs. I hope you get some relief from the sickness xx

I was worried whilst pregnant about long term use of ondansetron and went to the drs to ask them and the dr I saw showed me a new research study that was done in Australia between pregnant women taking ondansetron and pregnant women not taking it and found no difference in baby's health between the two, it was a fairly large research study in a number of 000s, definitely helped with the reassurance :-)

I found metoclopramide took several days to get to full effectiveness. I had to force myself to eat a bit at very specific times (to not let my stomach be completely empty). I had to be careful not to miss a tablet.
I also found the effect wore off after several weeks/months and had to switch between cyclizine and metoclopramide several times during pregnancy. Towards the end I was taking stemetil as well as the cyclizine.

Hello im new to the board. On my second pregnancy and had hyperemesis also wi...

Posted
21/09/2017

Hello im new to the board. On my second pregnancy and had hyperemesis also with my first. The dr gave me metachlopromide too and i had the same thing with stomach cramps. Im now on cyclizine. So far i feel okay but tired but could be because my lo kept waking me up last night too. I still need to eat allll the time or the nausea comes back. I wish i remembered the name of the medication that worked for me last time but was at a different drs. I hope you get some relief from the sickness xx

Hi, I'm 18 weeks on Saturday and still struggling. I'm on ondansetron and Promethazine hydrochloride. The ondansetron def helps, was much worse before I started it. I too have to make sure my tummy doesn't go empty or I really suffer. Nearly half way there now- the end is nigh!

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