The study, published online in the journal Cancer, included 59,806 women ages 50 to 79. Researchers gathered health and lifestyle data at the start of the study, and the women reported their health in yearly questionnaires over an average 12 years of follow-up. The women brought in their medicine bottles for the researchers to examine and record.

There were 548 incidents of melanoma during the period. After controlling for sun exposure, sunscreen use, a history of skin cancer and many other factors, the researchers found that women who reported using aspirin had an average 21 percent lower risk of melanoma compared with nonusers, and the longer they used aspirin, the lower their risk.

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