..A prospective double-blinded placebo-controlled trial was done to compare the efficacy and side-effects of sublingual to oral misoprostol when used with mifepristone for medical abortion from 12 to 20 weeks gestation...

Pilot study on the use of sublingual misoprostol with mifepristone in termination of first trimester pregnancy up to 9 weeks gestation

..A combination of mifepristone and misoprostol provides an effective method of medical abortion for early pregnancy. A new route of administration of misoprostol, the sublingual route, was investigated in this study...

A prospective randomized study on the measured blood loss in medical termination of early pregnancy by three different misoprostol regimens after pretreatment with mifepristone

..Prolonged vaginal bleeding is a common complaint after medical abortion. The effect of a 1 week course of daily oral misoprostol after medical abortion with mifepristone and misoprostol on the amount of post-abortal blood loss was studied...

A prospective randomized study to compare the use of repeated doses of vaginal with sublingual misoprostol in the management of first trimester silent miscarriages

..Other applications including treatment for fibroids, endometriosis and various cancers have been explored. However, its association with abortion limits the applications of mifepristone in many of these areas...

A prospective, randomized, placebo-controlled trial on the use of mifepristone with sublingual or vaginal misoprostol for medical abortions of less than 9 weeks gestation

..Further studies are required to determine the optimal dose and route of administration of misoprostol that can give the highest complete abortion rate, lowest ongoing pregnancy rate and least side effects...

Misoprostol: pharmacokinetic profiles, effects on the uterus and side-effects

..These studies can help to discover the optimal dose and route of administration of misoprostol for individual clinical applications. Misoprostol is a safe drug but serious complications and teratogenicity can occur with unsupervised use...

Pilot study on the use of repeated doses of sublingual misoprostol in termination of pregnancy up to 12 weeks gestation: efficacy and acceptability

..6) and 14.0 (2.5th-97.5th centiles: 0-99.1). These pain levels during egg collection were not significantly different between the two groups. The use of 200 mg lignocaine in PCB is not justified, even in the absence of toxic effects...

..Common side effects of misoprostol-induced termination of pregnancy include gastrointestinal side effects, abdominal cramps, bleeding, fever and chills. Complications may include infection or rarely rupture of uterus...

Vaginal misoprostol as medical treatment for first trimester spontaneous miscarriage

..This is the first randomized study to compare vaginal misoprostol versus expectant treatment in women presenting with spontaneous miscarriage...

Comparison of endometrial and subendometrial blood flows among patients with and without hydrosalpinx shown on scanning during in vitro fertilization treatment

Ernest Hung Yu NgDepartment of Obstetrics and Gynaecology, The University of Hong Kong, Hong Kong Special Administrative Region, People s Republic of ChinaFertil Steril 85:333-8. 2006

..To compare endometrial and subendometrial blood flows among patients with and without hydrosalpinx (HSP) during in vitro fertilization treatment as measured by a three-dimensional power Doppler ultrasound...

..We compared the ultrasonographic parameters for endometrial receptivity between 2 consecutive in vitro fertilization (IVF) cycles in the same patients...

WHO multinational study of three misoprostol regimens after mifepristone for early medical abortion. I: Efficacy

Helena von HertzenUNDP UNFPA WHO World Bank Special Programme of Research, Development and Research Training in Human Reproduction, Department of Reproductive Health and Research, World Health Organization, Geneva, SwitzerlandBJOG 110:808-18. 2003

....

The significance of the number of antral follicles prior to stimulation in predicting ovarian responses in an IVF programme

..To compare the efficacy, side effects and acceptability of sublingual and vaginal misoprostol for second trimester medical abortion...

Comparison of endometrial and subendometrial blood flow measured by three-dimensional power Doppler ultrasound between stimulated and natural cycles in the same patients

Ernest Hung Yu NgDepartment of Obstetrics and Gynaecology, The University of Hong Kong, Hong Kong Special Administrative Region, People s Republic of ChinaHum Reprod 19:2385-90. 2004

..Low implantation rates in stimulated IVF cycles may be related to suboptimal endometrial perfusion. Endometrial and subendometrial blood flow was compared between stimulated and natural cycles in the same patients undergoing IVF...

Endometrial and subendometrial blood flow measured during early luteal phase by three-dimensional power Doppler ultrasound in excessive ovarian responders

..To compare the side effect profiles of regimens of oral and vaginal administration of misoprostol after a single oral dose of 200 mg of mifepristone and to investigate patients' perceptions of medical abortion...

..Different doses of human chorionic gonadotropin (hCG) have been used in various in vitro fertilization (IVF) treatment protocols to achieve final oocyte maturation. There is as yet no agreement on the optimum dose required...

..There were no differences in all the indices of endometrial, subendometrial, and ovarian stromal blood flow in women who had received 250 microg or 500 microg of recombinant hCG for final oocyte maturation...

Bioavailability of hCG after intramuscular or subcutaneous injection in obese and non-obese women

..The bioavailability of a drug is affected by its route of administration. Herein, the bioavailability of hCG was compared after intramuscular (i.m.) or subcutaneous (s.c.) injection in obese and non-obese women...

Endometrial and subendometrial blood flow measured by three-dimensional power Doppler ultrasound in patients with small intramural uterine fibroids during IVF treatment

Ernest Hung Yu NgDepartment of Obstetrics and Gynaecology, The University of Hong Kong, Hong Kong Special Administrative Region, People s Republic of ChinaHum Reprod 20:501-6. 2005

..We compared endometrial and subendometrial blood flow between women with and without intramural fibroids during IVF treatment...

..To compare the biochemical markers of bone turnover in hypoestrogenic women who had been on the standard dosage of Premarin 0.625 mg to that of the age-matched women who were menstruating spontaneously...

Pilot study on the use of sublingual misoprostol in termination of pregnancy up to 7 weeks gestation

..This study was conducted to assess the efficacy and incidence of side effects of a regimen of repeated doses of 400 microg sublingual misoprostol for termination of pregnancy of <7 weeks gestation...

..The discriminative capacity of CAT in the diagnosis of tubal pathology including both proximal and distal obstruction was not improved by measuring serum CA-125, regardless of the threshold values of serum CA-125 concentration...

..These regimens are still effective with an abortion rate of >90% in 48 hours. However, the induction to abortion interval (15 hours) is much longer. Intra-cervical tents can be used to shorten the induction to abortion intervals...

The role of endometrial and subendometrial blood flows measured by three-dimensional power Doppler ultrasound in the prediction of pregnancy during IVF treatment

Ernest Hung Yu NgDepartment of Obstetrics and Gynaecology, The University of Hong Kong, Hong Kong Special Administrative Region, People s Republic of ChinaHum Reprod 21:164-70. 2006

..We aimed to evaluate the role of endometrial and subendometrial blood flows in the prediction of pregnancy during IVF treatment...

Endometrial and subendometrial vascularity is higher in pregnant patients with livebirth following ART than in those who suffer a miscarriage

Ernest Hung Yu NgDepartment of Obstetrics and Gynaecology, The University of Hong Kong, Hong Kong Special Administrative Region, People s Republic of ChinaHum Reprod 22:1134-41. 2007

..Blood flow towards the peri-implantation endometrium may have effects on miscarriage and live birth following assisted reproduction treatment, in addition to its role in implantation...

The role of endometrial and subendometrial vascularity measured by three-dimensional power Doppler ultrasound in the prediction of pregnancy during frozen-thawed embryo transfer cycles