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Arthritis

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Arthritis.

Arthritis is a group of autoimmune disorders, which involve different joints of the body and lead to damage of the joints. Involved joint/joints become inflamed and painful. The main presenting symptom of arthritis is generally joint pain and other joint problems, although symptoms (including presenting symptoms) may vary according to types of arthritis. Different types of arthritis may have different symptoms, for example deformity of fingers in rheumatoid arthritis, which is not generally seen in other types of arthritis, such as psoriatic arthritis.

The list of different types of arthritis is long and common types of arthritis are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, gouty arthritis, septic arthritis, arthritis secondary to other systemic diseases and many more. Osteoarthritis is the most common for of arthritis, which is due to degenerative changes in the involved joints due to wear and tear of joints. The most commonly involved joints in osteoarthritis are knee and ankle joints due to constant weight bearing.

What medications are available for treatment of arthritis?

The medications used in treatment may vary according to the type of arthritis. For example if arthritis is secondary to other disease, the primary disease also need to be treated along with arthritis. Treatment of arthritis involves treatment of symptoms of arthritis, such as pain and inhibition of progression of disease process.

Consumption.

Most of the medications used for treatment of arthritis are generally given orally, although some may have to be given parenterally and sometimes may be given as topical application.

Commonly at least two different types of medications are given, for symptomatic treatment and for preventing progression of disease. The treatment is done with drugs having least side effects and shifted to stronger drugs if disease progression continues.

Side effects.

Side effects of drugs used in treatment are common, as medications have to be taken for long duration and probably for life-long. Any medication (even comparatively safe drugs) if taken for prolonged time generally gives rise to side effects, which may not have side effects for short term use. To reduce side effects all the drugs should be taken under supervision of a physician.

Side effects of NSAIDs are common with in treatment of arthritis and include abdominal pain, intestinal bleeding, peptic ulcer, liver damage, kidney damage etc.

Glucocorticoids also have side effects in treatment of arthritis and include ulcer, weight gain, osteoporosis, cataract, diabetes, high blood pressure, hormonal disturbances etc. To reduce side effects of glucocorticoids, they are used for short duration to reduce acute symptoms.

The side effects of DMARDs include liver damage, bone marrow suppression, and risk of opportunistic infection.

The side effects of Immunosuppressants and tumor necrosis factor inhibitors include heart failure, high risk of infection (due to reduced immunity by Immunosuppressants), etc.

The information provided on this site is not intended to replace any advice given by your physician or other health care workers. Additionally, you should not attempt to utilize any of this information to treat or diagnose a medical problem without first seeking advice from a qualified medical professional. Further, it is vital that you read any and all instructions and precautions listed on the label of any medication you are prescribed. If you suspect you may be suffering from a medical issue please contact your doctor right away.