Reversible Technique Developed for Stem Cell Expansion

August 8, 2018

(Genetic Engineering & Biotechnology News) – Scientists at the Stowers Institute for Medical Research, and the University of Kansas Medical Center, have identified a way to expand blood-forming adult hematopoietic stem cells (HSCs) from human umbilical cord blood (hUCB), without differentiating the cells into mature blood cells. If the technique can be translated into a clinical setting, it could make cord blood HSC transplants more readily available to eligible patients with blood cancers, and immune and genetic disorders, for whom a suitable bone marrow donor can’t be found.