During a test on the launchpad, a fire kills Apollo 1 astronauts Virgil "Gus" Grissom, Ed White, and Roger Chaffee. Then, on April 24, 1967, the Soviet craft Soyuz 2 crashes on re-entry, killing Vladimir Komarov — the first cosmonaut to die during flight.

Apollo 11's Lunar Module on the moon's surface (NASA)

First Moon LandingJuly 20, 1969

During the flight of Apollo 11, Neil Armstrong becomes the first man to walk on the moon. Buzz Aldrin is the second. Armstrong says, "That's one small step for man, one giant leap for mankind." Millions of people watch live on television.

The Apollo 13 capsule after splashdown (NASA)

First Space RescueApril 13, 1970

An oxygen tank explodes aboard Apollo 13. With help from Mission Control, the crew — Jim Lovell, Fred Haise, and John Swigert — return to Earth safely four days later.

First Space StationApril 19, 1971

The Soviets launch Salyut 1, the first orbiting space station. Salyut 1's original crew die during re-entry on June 30, 1971. Georgi Bobroeolski, Vladislav Volkov, and Victor Patsayev had spent a record 23 days in space.

Skylab in orbit (NASA)

First American Space StationMay 14, 1973

The first American space station, Skylab, is damaged during launch. The first of three crews arrive 11 days later for a 28-day stay. They make in-orbit repairs and set records for time spent in space.