Several amino acids were tested for their effect on carregeenan-induced inflammation in the rat. If was found that creatine, creatinine, L-isoleucine. DL-isoleucine, L-glutamine. DL-tryptophan. L valine, DL-valine. L-methionine and DL-methionine were effective whereas the remaining compounds, taurine, L-histidine. (-alanine, L-arginine, L-swine, L-threonine and DL-threonins, were ineffective in reducing inflammation.