Causes

Any factor that increases pressure against the artery walls can lead to prehypertension. Atherosclerosis, which is the buildup of fatty deposits in your arteries, can lead to high blood pressure. Sometimes an underlying condition causes blood pressure to rise. Possible conditions that can lead to prehypertension or high blood pressure include:

Atherosclerosis

Obstructive sleep apnea

Kidney disease

Adrenal disease

Thyroid disease

Certain medications — including birth control pills, cold remedies, decongestants, over-the-counter pain relievers and some prescription drugs — also may cause blood pressure to temporarily rise. Illegal drugs, such as cocaine and amphetamines, can have the same effect.

Often, however, high blood pressure develops gradually over many years without a specific identifiable cause.

James PA, et al. 2014 evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA. 2014;311:507.

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