PrOCoil - Predicting the Oligomerization of Coiled Coil Proteins

We have developed an SVM-based classification method for predicting whether a
given coiled coil sequence is a trimer or dimer (assuming that it is one of both).
This method also allows for a deep analysis of the sequence which residues are
mainly responsible for the outcome. The software is available as an R package
procoil and as a simple-to-use Web application.

Important Note: the prediction models
have been updated with the release of version
2.0.0 of the PrOCoil R package. The updated data sets and some information on
how they have been collected are available from the PrOCoil Data Repository (v2).
If you want to use the original prediction models as published
by Mahrenholz et al. (2011), please follow the instructions in
Section 5.5.3 of the
user manual).
The data sets on which the original PrOCoil models were based are still available from the PrOCoil Data Repository (v1).

Installation

The R package procoil is available from
Bioconductor.
The current version of the package is 2.0.2 and has been released as part of
Bioconductor 3.3
on May 4, 2016. To install procoil, follow the simple standard procedure
for installing Bioconductor packages, i.e. enter the following into your R session: