Summariesfor NKX2-2 gene

The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the

central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be

duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear

transcription factor. (provided by RefSeq, Jul 2008)

GeneCards Summary for NKX2-2 Gene:

NKX2-2 (NK2 homeobox 2) is a protein-coding gene. Diseases associated with NKX2-2 include gastrointestinal neuroendocrine tumor, and neuroendocrine tumor. GO annotations related to this gene include chromatin binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is NKX2-1.