Python for .NET

Python for .NET is a package that gives Python programmers nearly seamless
integration with the .NET Common Language Runtime (CLR) and provides a
powerful application scripting tool for .NET developers. Using this package
you can script .NET applications or build entire applications in Python,
using .NET services and components written in any language that targets the
CLR (Managed C++, C#, VB, JScript).

Note that this package does not implement Python as a first-class
CLR language - it does not produce managed code (IL) from Python code.
Rather, it is an integration of the C Python engine with the .NET runtime.
This approach allows you to use use CLR services and continue to use existing
Python code and C-based extensions while maintaining native execution speeds
for Python code. If you are interested in a pure managed-code implementation
of the Python language, you should check out the
IronPython project, which is in
active development.