Cobalt(II) complex bearing amino benzothiazole
ligand has been synthesized and characterized. The ligand, acts as
monodentate, neutral ligand with N as the donor site. The Co(II) complex
shows low antioxidant activity against DPPH radical. Cytotoxicity of the
complex (IC50: 14.12 µM) against MCF-7 cell line is
comparable to that of cisplatin. In addition, the complex shows good
antimicrobial and antituberculosis activities. The DNA binding ability of the
ligand and complex, assessed by absorption spectra, reveals a minor groove binding
with binding constant = 1.24×104M-1.

Cu(II) complexes
with 3-ethyl-2-acetylpyrazine N(4)-isopropyl-thiosemicarbazone
has been synthesized and characterized.
The complexes can inhibit the proliferation of three cancer cell lines, viz.,
human hepatoma
cells SMMC-7721, human gastric cancer SGC-7901 and human pancreatic cancer
Patu-8988, which may be
related to increase of tumor cell apoptosis.

1314

Interaction
studies in binary liquid mixtures of ether and alcohols at different
temperatures

The
thermodynamic properties of binary liquid mixtures of triethyleneglycol
monomethyl ether and alcohols (1-hexanol,
1-octanol, 1-decanol) show that interaction decreases as the number of carbon
atoms in the alcohol molecule increases. Positive values of and ∆ show that volume expansion takes place on addition of
alcohols to the ether. The negative values of ∆u and Δη indicate the presence of weak
intermolecular forces which follow the order:
1-hexanol > 1-octanol > 1-decanol.

1325

Electrochemical impedance
spectroscopy of homo and copolymer of aniline and 2,4- dinitrophenol in a binary
electrolyte system

Electropolymerization
of PAni and poly(Ani-co-2,4 DNP) has been carried out in aqueous medium using
KCl and PTSA as supporting electrolytes. The charge transfer resistance of polyaniline and
copolymers of aniline with 2,4-dinotrophenol electrosynthesized
in presence of KCl is much less than that electrosynthesized in
its absence.

Ammonium dinitramide has been studied quantum
chemically at the UB3LYP/6-31++G(d,p) level in the presence of Be, Mg, B and
Al. ADN is reduced by Be and Mg, accompanied by the removal of NO2
moiety which has a negative total charge.

1342

Synthesis, structure, spectral and theoretical studies
of an organic decachlorotricadmate(II)

An organic chlorocadmate, built
up by 1-D polymeric chains formed by CdCl6 edge-sharing octahedra
has been prepared. Intermolecular interactions and crystal packing reveals
that the close contacts are mainly due to salt bridges and N–H…Cl
hydrogen bonds.

1347

Green synthesis of CuO/RHA-MCM-41 nanocomposite by
solid state reaction: Characterization and antibacterial activity

Rice husk, combusted
at 600 ºC for production of amorphous silica, is used for the preparation of
CuO/RHA-MCM-41 nanocomposites containing 5.0 and 10.0 wt.% Cu under solid
state reaction.

Authors for correspondence are indicated by (*)

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Cobalt(II)
complex of 2-amino-6-methylbenzothiazole has been synthesized and characterized
by various physico-chemical methods. The ligand 2-amino-6-methylbenzothiazole
acts as monodentate, neutral ligand with N as the donor site. The molecular
structure of the title complex has been determined by single crystal
X-ray diffraction studies. The Co(II) complex shows significant antioxidant
activity against DPPH radical. The complex shows cytotoxicity with a IC50 value
of 14.12 µM against MCF-7 cell line. In addition, the complex shows good
antimicrobial and anti-tuberculosis activities against various microbes and
mycobacterium tuberculosis respectively. DNA binding of the title complex has
been investigated by absorption spectroscopic technique, which reveals that the
complex acts as minor groove binder. These results have been validated by
molecular docking studies.

Five Cu(II) complexes, [Cu(L)2]·CH3OH (1),
[CuLCl] (2), [CuLBr] (3), [CuL(NO3)] (4) and [Cu2(L)2(SO4)]·3H2O·CH3OH
(5), based on HL (where HL = 3-ethyl-2-acetylpyrazine N(4)-isopropylthiosemicarbazone)
have been synthesized and characterized by X-ray diffraction analyses.The complexes (1) and (2) are mononuclear, while the other three are
binuclear. In vitro experiments
carried out to investigate the effect of complexes (1-5) on human
hepatoma cells SMMC-7721, human gastric cancer
SGC-7901 and human pancreatic cancer Patu-8988 show that complexes (1-5) can inhibit the proliferation of
all the three cancer cell lines. The inhibition of cell growth is related to
increase of tumor cell apoptosis, which is further confirmed by results of
western blotting wherein the expression of p53 and Bax increased, and expression
of Bcl-2 decreased in complex (3) treated SMMC-7721 cells.

Densities (ρ), speeds of sound ()and
viscosities (η) of binary liquid mixtures of triethylene glycol
monomethyl ether and alcohols (1-hexanol, 1-octanol, and 1-decanol) and those
of pure liquids at 293.15, 298.15, 303.15 and 308.15 K and atmospheric pressure
are reported over the entire composition range. Using the experimental results,
excess molar volumes (), isentropic compressibilities (), deviation of isentropic compressibilities (∆), deviation of the speeds of sound (∆u) and viscosity deviations () have been calculated to understand the intermolecular
interactions between the component molecules. These excess properties have been
correlated with composition using the Redlich-Kister polynomial equation. The
positive values of and ∆ show that volume expansion takes place on addition of
alcohols to the ether. The negative values of ∆u and also indicate
the presence of weak intermolecular forces which follow the order:
1-hexanol > 1-octanol > 1-decanol.

Electropolymerization of aniline and 2,4-dinitrophenol
on composite graphite electrode in phosphoric acid medium has been investigated
by cyclic voltammetry. The copolymer has been synthesized in a mole ratio of
1:1 of aniline and 2,4-dinitrophenol in aqueous medium with para-toluene
sulfonic acid and KCl as the binary supporting electrolytes. The properties of
the modified electrodes have been characterized and compared with each other by
FTIR spectroscopy. The inductive behavior of polyaniline and copolymers of
aniline with 2,4-dinitrophenol has been identified via electrochemical
impedance spectroscopy by determining parameters such as impedance and
capacitance.

Ammonium dinitramide (ADN) has been studied quantum
chemically at the level of UB3LYP/6-31++G(d,p) in order to get some information
about its behavior in the presence of some group II and III elements (viz., Be,
Mg, B and Al). The results indicate that Be and Mg are being oxidized by AND,
but B and Al are not. In the case of Be and Mg, the reduction of ADN is
accompanied by the removal of NO2 moiety which has negative total charge.
On the other hand, the interaction pattern of these elements with dinitramic
acid (HDN) in the presence of ammonia (HDN+NH3+element, ternary
composites) is different than the isomeric/isoelectronic binary (ADN+element)
composites. Some quantum chemical properties of those binary and ternary
composite systems are also presented.

Synthesis, crystal structure, DFT calculations, thermal analysis,
electrochemical measurements, IR, Raman and UV spectroscopic investigations of
an organic decachlorotricadmate(II) (C4H14N2)2[Cd3Cl10]
(C4H14N2 = N',N'-dimethylethane-1,2-diaminium) (1) are described. The structure of (1) provides a new one-dimensional polymer built up from a
trinuclear [Cd3Cl10]4- anion located in a
special position and charge balanced by an unique (C4H14N2)2+
cation. The anion and the organic cation are interlinked by N–HLCl hydrogen
bonds. Thermal analysis of (1)
reveals its anhydrous character.

The
fabrication and characterization of mesoporous siliceous MCM-41 nanoparticles
under room temperature using rice husk ash as an alternative cheap silica
source is reported. Rice husk, combusted at 600 ºC for the production of
amorphous silica, has been used for the preparation of CuO/RHA-MCM-41
nanocomposites containing 5.0 and 10.0 wt.% Cu under solid state reaction and
calcined at 300 and 500 °C. XRD results reveal diffraction peaks for each of
the two compounds in the nanocomposite. In the FT-IR spectra, all bands in
nanocomposite sample show a shift with respect to that of the matrix
nanoparticles, indicating that the copper oxide is incorporated in the matrix.
TEM images indicate that nanoparticles size of CuO is ~ 4 nm. The novel
nanocomposite exhibits excellent antibacterial activity against gram-positive (S. aureus) and gram-negative
(E. coli) bacteria.