... as well as humans. Different strains of the infectious agent, called a prion, cause mad cow disease, chronic wasting disease, and different forms of scrapie and human Creutzfeldt-Jacob disease.
Mad cow disease has had devastating consequences for bovine livestock populations, particularly in Europe, ...

... by decreased revenues for PACE (Police and Criminal Evidence Act) and paternity testing, and the expected lower volumes of animal DNA testing for scrapie susceptibility. In dollars, total U.K.-based revenues for the first quarter of 2009 increased by approximately 1% over the first quarter of 2008.
...

... and state DNA databases.
The decrease in U.K.-based revenues in the quarter compared to a year ago
was due to lower volumes of animal DNA testing for scrapie susceptibility
and slightly reduced forensics revenues due to adverse exchange rates.
Excluding cost of service revenue, operating expenses for the ...

... in U.K.-based revenues in
the second quarter of 2008, compared to the comparable period in 2007, was
due to lower volumes of animal DNA testing for scrapie susceptibility and
immigration identity testing, as well as reduced forensic revenue. The
decrease was partially offset by increased revenues in the ...

... the first quarter of 2008 compared to the comparable period in
2007 was due to lower volumes of immigration identity testing, animal DNA
testing for scrapie susceptibility and reduced forensic revenue.
Total operating expenses, excluding cost of service revenue, for the
first quarter of 2008 were $7.0 ...

... anticipated decrease in our U.K. agricultural revenue due to
a government policy change to test only male sheep under the U.K.
government National scrapie Plan."
Mr. Bologna concluded, "All in all, I believe we are making good
progress on many fronts but the very nature of our business is such that ...

... Chemistry, a semi-monthly journal.
Prions are infectious proteins that can cause deadly nerve-damaging diseases such as Mad Cow Disease in cattle, scrapie in sheep, and a human form of Mad Cow Disease called variant Creutzfeldt-Jakob Disease. Conventional tests are designed to detect the proteins only ...

... Creutzfeldt-Jakob disease, mad cow disease, scrapie and other prion diseases in animals – during ... resin-filtered blood were infected with scrapie by the end of the 550-day test. Fifteen of 99 ... at the end of the testing period. No evidence of scrapie was discovered in brains of hamsters that were ...

... case or cases of BSE is currently unknown. Sheep scrapie or a previously undetected bovine transmissible ... India states: “So far not a single case of BSE or scrapie had been reported from India, except for one case of scrapie from the Himalayan foothills in a sheep, which ...

... BSE or scrapie; the BSE donors were experimentally infected,
while the scrapie donors had naturally acquired the disease. While scrapie
is not thought to ... blood
donors.
The outcome of the experiment showed that both BSE and scrapie could be
effectively transmitted between sheep by blood transfusion. ...

... More on scrapie Prion - unidentified infectious agent thought ... s -- kuru of the Fore people of New Guinea and scrapie of ... The most widespread TSE in animals is scrapie , a disease that has affected sheep and goats ...

... compared to a year ago was due
to lower volumes of animal DNA testing for scrapie susceptibility and slightly
reduced forensics revenues due to adverse ... a challenging industry
environment where pricing pressures, declining U.K. scrapie orders and adverse
foreign exchange rates all contributed to the revenue ...

... of the normal form of the protein into its pathogenic form, which causes scrapie and mad cow disease. A team headed by Christian F. W. Becker at the TU ... of membrane association on conversion of the protein into the pathogenic scrapie form. This should finally make it possible to track down the infectious ...

... One of the new in vitro tests, called the Standard scrapie Cell Assay, measures prion infectivity levels in a highly accurate and ... for them to become lethally infected.
In contrast, the new Standard scrapie Cell Assay is based on prion-susceptible cell lines. In the test, cells ...

... infective prion agents -the pathogens responsible for conditions such as scrapie and Creutzfeldt-Jakob disease - into the nervous system, according to new ... lymph nodes that is part of the body's defence system - in the spread of scrapie infection to nerve tissue in hamsters. The team discovered that if a lymph ...

... have identified a small number of other prions in humans and other animals, most of which cause degenerative neurological diseases, including scrapie in sheep and goats, and Creutzfeldt-Jakob disease in humans. A few prions have also been found in model organisms, such as yeast.
Believing the ...

... prion disorders are sporadic, inherited, and infectious, and affect both humans and animals; common examples are mad cow disease in cattle, scrapie in sheep, and Creutzfeldt-Jakob disease in humans. The causative agent is a misfolded protein referred to as PrP-scrapie that replicates itself by ...

... DNA and RNA, prions are believed to cause such fatal brain ailments as chronic wasting disease (CWD) in deer and moose, mad cow disease in cattle, scrapie in sheep and Creutzfeldt-Jakob disease in humans. In addition to being perhaps the weirdest infectious agent know to science, the prion is also the ...

... work as a trigger to a set of diseases of the brain and nervous system, the so-called spongiform encephalopathies. These include BSE in cattle, scrapie in sheep and Creutzfeldt Jakobs Disease in humans. Prions are structural variants of a normal protein found in healthy tissues especially in the ...

... slow down the progress of the fatal brain disease scrapie in mice. This has been established by researchers ... awarded this year’s Nobel Prize for Medicine. scrapie is a variant of the cattle disease BSE and the ... yet there is no cure.
In mice suffering from scrapie the pathogenic prion protein is known as PrP-Scr, ...

... with different degrees of genetic resistance to scrapie ?the sheep form of the disease. When they ... gut with a fluid mixture containing 0.5 grams of scrapie infected brain containing a large amount of the ... just a secondary marker of the presence of the scrapie agent," says Jeffrey.
His belief in this need ...

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