Dual Monitor Setup - Windows 8.1

Let's say I have 2 monitors. One is 2560x1400 27" and is the primary one. The second is 1920x1080 24". I want to have a full-screen game on monitor 1 and have the second one to have open the web browser or anything else. Considering both are different resolutions will this setup work and not distort things like wallpapers etc..?

Alot of people run multiple monitors with different resolutions. I use "dual wallpaper tool" so I can have different wallpapers on each monitor. You can game and have a browser open on the other but it will minimize the game if you want to use the other screen.