The traditional roles of the tumor suppressor protein, p53, in transcriptional regulation are mostly defined in cancer or stressed cells and are centered on control of the cell cycle, DNA repair or senescence. In this thesis, data is presented...

A sea-level database following a new protocol of quality evaluation standards has been constructed and is used for a comparative analysis to reconcile conflicting hypotheses about Holocene relative sea-level change in the Gulf of Mexico....

Degradation processes change the chemical composition of oil and can be affected by the mixing of oil into the environment. Here, a ramped pyrolysis (RP) isotope technique is implemented to investigate thermochemical and isotopic changes in...

Several aryl acetylenes and aryl olefins have been examined as substrates and inhibitors of cytochrome P-450 dependent monooxygenases in liver microsomes from 5,6-benzoflavone or phenobarbital pretreated rats. Methyl 1-pyrenyl acetylene (MPA),...

The purpose of this study is to elucidate the historical processes that have impacted the fishes of the Fouta Djallon highlands and surrounding areas. This mountainous region in Guinea, West Africa, lies on the northern edge of the Guinean Range....

Objective. To examine the relationship between race, blood pressure (BP), and illicit drug use with the decline in renal function in hypertensive males
Methods. This study uses a non-concurrent cohort study design with repeated measurements on risk...