Nineteenth-century laws making abortion illegal in Queensland have been scrapped, in one of the state's biggest legislative reforms.

Key points

The new laws mean women will be able to access abortion up to 22 weeks' gestation

All MPs were given a conscience vote, passing the bill 50 to 41

The decision is the first change to the law in 119 years

The Government's controversial plan to decriminalise pregnancy termination passed through state parliament with a comfortable margin of 50 votes to 41.

The laws mean abortion will be available, on request, at up to 22 weeks' gestation.

It also allows an abortion to take place after 22 weeks if the medical practitioner performing the termination has consulted with a second medical practitioner and both agreed that "in all the circumstances" the abortion should be performed.

Attorney-General Yvette D'Ath said these laws would finally bring Queensland into the 21st century.

"I am so proud, as the Attorney-General of this state, as a woman, as a mother, to witness this significant reform which provides long-needed clarity," Ms D'Ath said.

"We've done this for our mothers, our sisters, our daughters, our friends. For women who have fought long and hard for the right to autonomy over their own bodies.

"Termination is never an easy option for any woman, and no one ever makes this decision lightly, but all women across Queensland should have the right to make the decision for themselves and without fear of criminal prosecution."