应用

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用

Ab评论

说明

WB

1/500 - 1/1000.

ELISA

1/20000.

IHC-P

1/50 - 1/100.

靶标

功能

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

组织特异性

Expressed in larger amounts in spleen and lung. Detected in liver, heart, small intestine, colon, thymus, prostate, skeletal muscle, peripheral blood leukocytes, kidney and testis. No expression in the brain.

序列相似性

Belongs to the peptidase C14A family.Contains 1 CARD domain.

翻译后修饰

The two subunits are derived from the precursor sequence by an autocatalytic mechanism.

Thank you for your inquiry.
I can confirm that there is no BSA in the buffer and that the antibody recognizes Caspase-1 subunit p10. There are no references citing the usage of this antibody in ELISA or IP. As far as we're aware, this antibody ha...