Courses

Activities

u-stem courses will consist of a series of elective and interactive activities held by
international recognized experts in the field of stem cells, gene therapy and tissue engineering. Participants will then have the
opportunity to attend the research laboratories of teachers with the aim:

i) to carry out practical laboratory experiments on how to grow, differentiate and manipulate stem cells;

ii) to learn the mechanisms / techniques of gene editing and transplantation of stem cells in experimental models,

iii) to increase / implement the knowledge and creativity for formulating, then resolving a scientific problem.

iv) know how to do a critical analysis of scientific results

v) communicating results.

Job placement

Upon completion of the master, students can expect to work in basic or applied research in different fields of stem cell biology
and gene editing, either by undertaking a PhD, or by finding employment in the research and development professions in the academic and private research institutes, in non-profit foundations, or
in corporate sectors, particularly in the field of biotechnology and regenerative medicine. Courses will be focusing on preparing students for the following
jobs/careers :

Module 4Lectures on gene therapy and genome editing in stem cells for disease correction. Student led “mock trial” on Crispr
technology - pros and cons for research and clinical applications. Group activity of research project simulation. TutorsIsabella Saggio and Fiammetta Verni’6 CFUs

Module 5Epigenetic of stem cells for the analysis of molecular networks regulating self-renew and differentiation in stem
cells, with a particular emphasis on transcriptional and post-transcriptional regulation of pluripotency. Tutor Domenico Raimondo4 CFUs

Seminars and LaboratoryReading and discussion of recent papers by a selection of external speakers, and
attendance at the speaker’s seminars. Classroom discussion on how to build a presentation for various audiences on topics related to stem cell biology and regenerative medicine.8 CFUs

StageIndependent research conducted under the guidance of faculty supervisor in basic and
applied stem cell research, gene therapy and regenerative medicine in u-stem Core labs in Italy and abroad.Students will be encouraged to develop a wide a range of skills in order to gain concrete
insights into job placement opportunities. At least two different labs will have to be chosen by u-stem students. If a non-Italian lab is also selected, the internship is supported by the 2000
euros u-stem fellowship. 10 CFUs

Final examWriting, in the form of a scientific paper, of a scientific patent, or of a clinical trial submission, a report related with the scientific work performed during the
internship. 6 CFUs