This has been answered many times in the forums, you can manage any number of domains. Minyou, it depends what you mean by 'manage several different domains'.

Sorry to ask an already answered question, by "manage" I would say one main domain as mysomain.com (mailbox, send and receive pop imap, etc) and other domain as thisdomain.org (mailbox, send and receive pop imap, etc) and share or not briefcase and calendar with the other domain(s).

Sorry to ask an already answered question, by "manage" I would say one main domain as mysomain.com (mailbox, send and receive pop imap, etc) and other domain as thisdomain.org (mailbox, send and receive pop imap, etc) and share or not briefcase and calendar with the other domain(s)..

The answer is still yes, there's no restrictions on the number of Domains that Zimbra can host nor on the Sharing function.