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Bloom Lab

Cultured wild type mouse brain cells were incubated for 24 hours with amyloid-β oligomers in the presence of the synthetic nucleotide, BrdU, and then were stained for immunofluorescence with antibodies to MAP2 (green) to identify neurons and to BrdU (red) to identify newly synthesized nuclear DNA.

Grainger Lab

Provencio Lab

Light is critical for many biological processes. While vision is the most obvious of these, much of our "non-visual" physiology is regulated by light. For example, the internal 24-hour (circadian) clock that controls daily rhythms such as our sleep:wake cycle is reset by light.

Deppmann Lab

Kozminski Lab

Many species depend upon asymmetric or polarized cell growth for life. Using the yeast S. cerevisiae, we investigate how eukaryotic cells regulate polarized cell growth in relation to the cell cycle, lipid metabolism, and small G protein-mediated signaling. Yeast defective in these processes (center and right) reveal the molecular events that regulate polarized cell growth in normal cells (left).

Roach Lab

To understand how selection acts to shape the patterns of morphology, reproduction and mortality, we do studies of marked individuals in natural populations. Our current work includes projects on the impact of invasive species on evolution in communities, comparative demography across the range of an endemic species, the impact of inbreeding on adaptation, and plant aging.

Brodie Lab

I am broadly interested in how interactions at different levels of biological organization drive the evolutionary process, from epistasis between loci within a genome, to social interactions among individuals in a population, to coevolutionary arm-races between species in a community.

Galloway Lab

We use ecological and genetic approaches to explore patterns of evolution in natural plant populations. We are currently exploring mechanisms of incipient speciation, the consequence of multiple chromosome copies represented by polyploidy for reproductive isolation, geographic-scale patterns of mating system evolution and the contribution of transgenerational maternal effects to adaptive evolution.

Blackman Lab

Many plants, like these wild sunflowers, use environmental cues like photoperiod to time the onset of flowering so that reproduction occurs in the appropriate season. The Blackman lab studies how evolution alters these and other environmentally sensitive responses through genetic changes as plant populations adapt to local habitats or become domesticated.

Kucenas Lab

Our lab is generally interested in how the nervous system is assembled and maintained. More specifically, we're investigating the role of glial cells in: 1. formation of the nervous system early in development, and 2. nervous system preservation during disease and injury.

Hirsh Lab

Wu Lab

We are interested in studying how microbes evolve, adapt and diversify at the molecular, organismal and community levels. To gain insights into the fundamental mechanisms underlying these processes, we use an interdisciplinary approach that draws upon the fields of genomics, evolutionary biology, computational biology, and ecology.

Cox Lab

Our research lies at the interface of two topics: (1) the evolutionary dynamics associated with the divergent reproductive roles of males and females, and (2) the ecological factors that shape natural selection on physiology, morphology, and life history.

Adler Lab

Many animal tissues are polarized along two axes. One is apical/basal polarity, which has been intensively studied in many cell types. The second is planar cell polarity, which is the focus of this laboratory. The frizzled/starry night pathway appears to regulate this process in a wide variety of animals.

Siegrist Lab

The Siegrist lab is working to elucidate the molecular mechanism that leads to the progressive restriction of neurogenesis normally during development. Pictured is the Drosophila CNS imaged at three different developmental stages. Termination of neurogenesis and cell proliferation in the brain coincides with the disappearance of the neural stem cell population.

Welcome to The Department of Biology at the University of Virginia.

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