As a two-time all-Mid-American Conference center, Embry, a team captain, led the then-Redskins to conference championships and NCAA Tournament appearances in 1957 and 1958. He led the MAC in scoring and rebounding in two seasons and still holds several school records, including best career rebounding average (15.5). He ranks among Miami leaders in the all-time scoring list with 1,401 points and rebounding list with 1,117. He holds both Miami and MAC records for most rebounds in a game (34) and season (488). During his career, he was one of only 10 players in MAC history to total more than 1,000 career points and rebounds.

He was selected to the Helms Athletic Foundation All-America third team as a senior, and he was a two-time honorable mention All-America selection in 1957 and 1958.[2]

He was inducted in the second class of the Miami Athletics Hall of Fame in 1970.[2] He became the fourth player in Miami history to have his jersey (23) retired.[1]

He played in the NBA All-Star game for five consecutive seasons (1961–1965) and won the NBA Championship with the Celtics in 1968.

Embry was originally drafted by the St. Louis Hawks in 1958. He was then traded closer to home weeks later to the Cincinnati Royals. The Royals were rebuilding due to the collapse of the team following the hospitalization of team star Maurice Stokes. Star center Clyde Lovellette was traded to St. Louis for Embry and four others.

Oscar Robertson arrived to the team in 1960, reviving the Royals. Embry, Robertson and Jack Twyman were all NBA All-Stars for Cincinnati over the next three years. Embry's play was notable for his pick and roll play with Robertson, whose encouragement improved Embry's game. A powerful 6'8" and 240 pounds, Embry at times appeared to be a blocker on the court, a protector of teammates. But he also had a fine all-around game.

Retiring to be a regional sales leader for Pepsi-Cola, Embry was talked out of retirement by friend Bill Russell, the new player/coach for Boston. Embry played crucial reserve minutes for Russell and aided that team's surprising 1967–68 NBA title run. When the Milwaukee Bucks were formed, they claimed Embry from the Celtics and Embry centered the Bucks for the 1968–69 season.

Embry later became an assistant manager for the Bucks, keeping an eye for former Royals teammates he could lure to the rising contender. He was instrumental in numerous signings to aid the team, including Robertson. His remarkable teaming with then-named Lew Alcindor quickly produced an NBA title, with Embry by then rising into Milwaukee's front office.

In 2004, Embry was hired to be the Senior Basketball Advisor to the rookie General Manager for the Toronto Raptors, Rob Babcock. After one season, Embry was elevated from Senior Advisor to President, bypassing Babcock in the chain of command when the board cited a lack of confidence in Babcock's moves. On January 26, 2006, Embry was also named the interim general manager for the Raptors after the firing of Babcock, a position he held for two months until Bryan Colangelo was hired as the new general manager. Embry has since continued to serve as Senior Basketball Advisor for the Raptors.

Embry and his wife, Terri, have two daughters and one son he also has a granddaughter.[4][3]

He has distant relatives, Marty Embry, and Marty's son, Jovan. Marty played collegiate for the DePaul Blue Demons and was drafted in the 1986 NBA Draft by the Utah Jazz. He played 13 seasons as a professional basketball player. Jovan, at 6'11, committed to play for Mississippi Valley State University in 2016.

He has been a founder and CEO of his own businesses, and member of numerous nonprofit and corporate boards of directors, including Kohl's, Federal Reserve Bank of Cleveland, Centerior Energy and Ohio Casualty Insurance.[3] He has been a community activist and mentor for youth in every city where he has lived and worked.

He is also the author of an autobiography, "The Inside Game: Race, Power and Politics in the NBA" (University of Akron Press, 2004), with Mary Schmitt Boyer of the Cleveland Plain Dealer.

Embry has been a trustee of the Naismith Memorial Basketball Hall of Fame since 1974 and has served on various senior-level committees for the NBA and USA Basketball. In recognition of his career both on the court and in the front office, he was inducted into the Naismith Hall of Fame as a contributor to the sport in 1999.

Embry was inducted into the Ohio Basketball Hall of Fame in 2006 as a member of the charter class.[1] He was the 2013 recipient of the Ohio Heritage Award, recognizing an Ohio Basketball Hall of Fame inductee for his or her contributions to the state of Ohio off the court.

A portion of US Route 40 in front of Tecumseh High School near Springfield, Ohio, was named in Wayne Embry's honor.[5]