Abstract

Benzimidazole in medicinal chemistry: An overview

Benzimidazole is a bicyclic heterocycle system consisting of two nitrogen atoms and fused phenyl ring shows wide range of biological activities. Benzimidazole can be synthesized using ophenylenediamine and carboxylic acid. Benzimidazole posses wide spectrum of biological activities like including antibacterial, antifungal, antiviral, anti-inflammatory, anticonvulsant, antidepressant, antihypertensive, analgesic, and hypoglycemic properties. The present reviews attempted to gather the various developments in synthesis and biological activities of Benzimidazole derivatives.