you are allergic to any ingredient in endep you are currently taking or have taken a monoamine oxidase inhibitor maoi eg, phenelzine, selegiline within the last 14 days you are taking antihistamines eg, diphenhydramine , cisapride, droperidol, a ketolide eg, telithromycin , a macrolide eg, erythromycin , mibefradil, or pimozide you are recovering from a heart attack.