Inventor

Document Type

Patent Number

Patent agency

Publication Date

Assignee

The United States of America as represented by the Department of Health and Human Services (Washington, DC, US) ; University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

09/533,427

Date Filed

2000-03-22

Total Pages

86 pages

Abstract

The present invention provides methods of delivering nucleic acids to specific regions, tissues and cell types of the CNS. More particularly the invention provides methods of delivering nucleic acids to cells of the CNS such as cerebellar cells and ependymal cells. The invention also provides methods of delivering nucleic acids to cells of the lung such as alveolar cells using AAV5 vectors and particles.