Academy-Award winning actresses Susan Sarandon and Kathy Bates, and Melissa McCarthy, star of the 2011 hit “Bridesmaids,” will be in Niagara Falls Thursday to shoot scenes for a movie.

“Tammy,” a comedy, is about a woman, portrayed by McCarthy, who after losing her job and finding out her husband has been unfaithful, hits the road with her hard-drinking grandmother, played by Sarandon.

The Warner Bros. film is being directed by Ben Falcone, McCarthy’s husband. The couple co-wrote wrote the screenplay.

Other cast members include Dan Aykroyd, formerly of “Saturday Night Live,” and Allison Janney, who co-starred in the popular TV series “The West Wing.”

A number of local actors and crew are being hired to work with the film crew for what is expected to be a one-day shoot. This comes on the heels of the Universal Pictures’ “Best Man Holiday,” which recently turned Bills Stadium into Giants Stadium and included a number of locals hired as extras.

The local filming is expected to be in Niagara Falls State Park at the renovated Cave of the Winds attraction, and won’t be accessible to the public.

The rest of “Tammy,” which has a tentative release date of July 2014, is being shot on location in North Carolina.

Buffalo Niagara Film Commissioner Tim Clark had no official comment but said filming of other major motion pictures would be occurring in the region in the near future.

Sarandon is a five-time nominee who won an Oscar in 1996 for a leading role in “Dead Man Walking.” Bates, a three-time nominee, won an Oscar in 1991 for a leading role in “Misery.” McCarthy, in addition to “Bridesmaids,” has had TV success with co-starring roles in the “The Gilmore Girls” and “Mike & Molly.”

In other local movie news, veteran actor and Cheektowaga native William Fichtner walked the red carpet at Disneyland Friday for the premiere of “The Lone Ranger,” with Armie Hammer in the lead role and Johnny Depp as Tonto. Fichtner co-stars as the villain Butch Cavendish. Fichnter is also starring in “Teenage Mutant Ninja Turtles,” now shooting in New York City.