Here we explore association with human longevity of common genetic variation in three
major candidate pathways: GH/IGF-1/insulin signaling, DNA damage signaling and repair
and pro/antioxidants by investigating 1273 tagging ...

In 2004, the integrated European project GEHA (Genetics of Healthy Ageing) was initiated
with the aim of identifying genes involved in healthy ageing and longevity. The first
step in the project was the recruitment of more ...

Clear evidence exists for heritability of human longevity, and much interest is focused
on identifying genes associated with longer lives. To identify such longevity alleles,
we performed the largest genome-wide linkage ...