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Affymetrix is collaborating with the University of Nijmegen in the Netherlands, the University of Tuebingen in Germany and the NHS Regional Genetics Laboratory in Birmingham, U.K. for the European Cytogenetic Research Initiative to investigate causes of mental retardation,

microarray technology will be used to try to identify the specific causative mutations in mentally retarded children.

Currently, cytogeneticists use karyotyping and FISH technologies to study deletions, amplifications and other chromosomal rearrangements..