Previous GeneCards Identifiers for AVIL Gene

Summaries for AVIL Gene

Entrez Gene Summary for AVIL Gene

The protein encoded by this gene is a member of the gelsolin/villin family of actin regulatory proteins. This protein has structural similarity to villin. It binds actin and may play a role in the development of neuronal cells that form ganglia. [provided by RefSeq, Jul 2008]

GeneCards Summary for AVIL Gene

AVIL (Advillin) is a Protein Coding gene.
GO annotations related to this gene include actin binding.
An important paralog of this gene is VIL1.

UniProtKB/Swiss-Prot for AVIL Gene

Ca(2+)-regulated actin-binding protein. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis.

Function for AVIL Gene

Products:

Molecular function for AVIL Gene

UniProtKB/Swiss-Prot Function:

Ca(2+)-regulated actin-binding protein. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis.

Primer Products

No data available for
mRNA differential expression in normal tissues ,
Protein tissue co-expression partners and
Phenotype-based relationships between genes and organs from Gene ORGANizer
for AVIL Gene