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She began with singing at 14 and her first album was released when she was 22. Before, she had made classical music. Her music-style is Pop-Rock, with Soul and R'N'B Influences. Her voice has a range by more than 4 octaves, sounds rough in the depth and strong in the higher ranges.

Her first concert was in 1982. In 1986, she joined the Band 'The Stealers' and founded her own band, 'Jule Neigel & Band' (her nickname was "Jule" until 2005). Her first hit, "Schatten an der Wand" was released in 1987 (#12 in Germany). The first record sold about 200,000 copies and was produced by Ralf Zang, who also was the producer of Chaka Khan. Since then, she sold more than 2 million records, by releasing seven records in 10 years. She worked together with Simon Phillips, Paco de Lucia, Helmut Zerlett, Udo Lindenberg, and Peter Maffay. In 2006, she released the live record, "Stimme mit Flügeln."

She has resumed using her birth name, Julia Neigel. She has performed with Ronan Keating, Ricky Lee Jones, Toto, Status Quo, and Mousse T. In 2010 she took part in the "Rock´n soul Tour" with the German singer Edo Zanki.