"Every once in a while, I can catch a glimpse of her when she doesn't see me looking. I have this moment where I'm like, 'If you never make a good decision – if you only make bad decisions – for the rest of your life, you made one really good decision,'" he told the talk show host of his wife.

Calling the actress his "best friend," Timberlake, 32, said his relationship with Biel "suits me."

When Biel appeared on the same show in November, she said, "The weirdest and kind of most wonderful thing [about being married] is that word. That's my husband."