..a. 22-44 and 351-357) artificially linked together by glycine, exhibited a potent antiviral activity with IC50 of about 0.1 microM. This novel peptide is a promising candidate as a therapeutic agent against this deadly emerging pathogen...

Structural analysis of a highly glycosylated and unliganded gp120-based antigen using mass spectrometry

Young B KimDepartment of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USAVirology 305:124-37. 2003

..However, the observation that the immune responses could be redirected by altering the protein composition might allow us to explore alternative strategies for modifying the antigenic properties of HIV-1 envelope glycoprotein...