"We're at the beginning of another great wave of tech innovation, and I am incredibly excited by the opportunity to help the next generation of Internet technologies and leaders," Meeker said in a statement.

Kleiner Perkins Caufield & Byers is well-known in the tech industry for investing in Google, Amazon, Zynga and many other companies.

Meeker led a research team covering many of the same companies at Morgan Stanley, including Google and Amazon, as well as others tech heavyweights such as Microsoft, Yahoo! and EBay. Meeker joined Morgan Stanley in 1991.