GenAge entry for ule-5 (Caenorhabditis elegans)

Gene information (ID: 2160)

Potential relevance to longevity and/or ageing

Observations

Worms overexpressing ule-5 demonstrated a decrease in median lifespan (27%) when compared to the control. Two expression lines were used. These results were consistent for other uterine proteins. Additionally, simultaneous downregulation of ule-3, ule-4, ule-5, and ule-2 increased lifespan by 15-20% compared to the control.