Live.04 is Isis's fourth live release and the first to be composed of recordings from several different sources and eras. Many of the tracks are from audience bootleg recordings, and as such do not sound professionally recorded. The exception is the first track, recorded for WMBR Radio Boston. As with the rest of the live series, the CD version was self-released.[1] The vinyl edition was handled, in this instance, by Robotic Empire.[2]

Along with all Isis' other live albums, it is set to be re-released on July 12, 2011 in digital format, almost a full year after Isis' dissolution. It marks the fourth of the series released to a fortnightly schedule.[3]