@article{astmh:/content/journals/10.4269/ajtmh.2012.11-0386,
author = "Freitas, Vanessa C. and Parreiras, Klívia P. and Duarte, Ana Paula M. and Secundino, Nágila F. C. and Pimenta, Paulo F. P.",
title = "Development of Leishmania (Leishmania) infantum chagasi in Its Natural Sandfly Vector Lutzomyia longipalpis",
journal= "The American Journal of Tropical Medicine and Hygiene",
year = "2012",
volume = "86",
number = "4",
pages = "606-612",
doi = "https://doi.org/10.4269/ajtmh.2012.11-0386",
url = "http://www.ajtmh.org/content/journals/10.4269/ajtmh.2012.11-0386",
publisher = "The American Society of Tropical Medicine and Hygiene",
issn = "0002-9637",
type = "Journal Article",
abstract = "Abstract.
We analyzed the development of Leishmania (Leishmania) infantum chagasi in its natural sandfly vector Lutzomyia longipalpis. In addition, we compared sandfly infections initiated with axenic amastigotes or promastigotes. Our data showed no important difference between Lu. longipalpis infection rates resulting from either type of infections. Furthermore, development of infection was equivalent in both cases. All promastigote forms were found inside the sandfly and, after blood digestion, most of the population consisted of procyclics and nectomonads. A low percentage of metacyclic forms was coincident with a high number of nectomonads during late stages of infection, but which form gives rise to metacyclic forms in L. infantum chagasi is unknown. These results also show that the promastigote infection model, at least for this situation, is suitable for obtaining of infected sandflies because it is easier and less laborious.",
}