Composition - 1 ml:

A) Lyophilizate

B) Solvent

Diluent A 1 ml

Target species:

Cattle from one day of age.

Indications:

Both the prevention and treatment of bovine trichophytosis.

Contraindications:

Other immuno-prophylactic interventions are contraindicated during the period from 10 days before the first vaccination till 20 days after the second (third) vaccination; no oral preparations having the antimycotic effects shall be also applied to calves; the vaccinated animals shall not be kept together with other cattle infected by trichophytosis. Penicillin, streptomycin, tylosine, tetracycline or sufonamide may be used when calves should be treated with antibiotic preparations during the vaccination against trichophytosis in order to avoid the risk that the immunity against trichophytosis being formed would be affected significantly.

Adverse reactions:

Total anaphylactoid response can occur rarely, obviously within two hours after the vaccine application. If the anaphylactoid response occurs the preparations with antihistamine effect (adrenalin, calcium) should be immediately applied. Thin surface crust 10 mm – 20 mm in diameter that drops off spontaneously within 2 – 4 weeks can appear at the application spot 10 – 14 days after the vaccination.

Dosage for each species, route and method of administrations:

Prophylactic and therapeutic:

Calves aged one day up to three months: 2 x 2 ml

Cattle older than three months: 2 x 4 ml

The interval between the vaccination and the revaccination should be 5 – 14 days. Another (the third) revaccination can be performed 2 – 4 weeks after the revaccination in the animals affected heavily with trichophytic changes and also in cachectic animals.

Intramuscular at the lumbar or gluteal region. Vaccination and revaccination should be performed into the left and the right part of a body, respectively.

Advice on correct administration:

Lyophilizate shall be dissolved with Diluent A enclosed before use. Rubber gloves should be used during the vaccination.

Withdrawal period:

Meat: 14 days.

Special storage precautions:

Keep out of the reach and sight of children. Store and transport refrigerated (2 °C – 8 °C). Protect from frost. Protect from light. Do not use after the expiry date stated on the package. The vaccine shall be consumed within 2 hours since its dissolution.

Special warnings:

The latent disease can be provoked when animals being in the incubation stage of the disease are vaccinated. Their clinical conditions could impair temporary but the trichophytic changes apparent on skin disappear gradually spontaneously.
All animals kept in the breeding shall be vaccinated. Analogously all newly included calves or newly delivered animals shall be additionally vaccinated because Trichophyton verrucosum is very resistant and can survive in the animal’s environment for 6 – 8 years.

Special precautions for the disposal of unused product or waste materials:

The vials and all means used shall be inactivated; never let them in a shed. 2-% Ajatin solution, 1-% peracetic acid solution (for 4 hours) and/or inactivation by heat (100 ºC, 2 hours) are recommended for inactivation.

Other information:

Mechanism of action: Immunity of the cellular type and partially of the humoral type is induced in the immunized animals. Immunity onset is apparent within 1 month after the revaccination and lasts at least 5 years.Interactions: Parenteral or oral treatment with antimycotic preparations should not be performed simultaneously with the vaccination. No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product except the products mentioned above. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis. For animal treatment only! Veterinary medicinal product subject to prescription!