This report contains estimates of hydrochlorothiazide (HCTZ), angiotensin-converting enzyme inhibitor (ACEI), and angiotensin II receptor blocker (ARB) utilization in the Sentinel Distributed Database (SDD). Data from January 1, 2000 to June 30, 2018 from 17 Data Partners contributing to the SDD were included in this report. This request was distributed to Data Partners on August 20, 2018.