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El Instituto de Salud CarlosIII(ISCIII) is the head of BioNER, being its operational and functional management and direction attributedto Instituto de Investigación de Enfermedades Raras (IIER). BioNERentered in el Registro de Biobancoswith registration numberB.0000886 on November 14th 2013and the filethat controlsand stores the datais alsoregistered with theSpanish Data Protection Agency(AEPD) under number 2060180217, onJuly 5th 2012, under the name of“Registro de Enfermedades Raras y Banco de Muestras”.