Effects of Hypericum Perforatum on Effectiveness of Oral Contraceptives

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New York,
New York10032

Purpose:

The purpose of this study is to evaluate the effects of a common herbal remedy, St. John's
Wort, on the effectiveness of birth control pills. St. John's Wort has recently been shown
to increase metabolism of some drugs. If it could increase metabolism of oral contraceptives
as well, it may increase the risk of contraceptive failure and unintended pregnancy. Study
participants will be evaluated for risk of ovulation on oral contraceptives before and
during simultaneous therapy with St. John's Wort.