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By starting with a basic Piranha II, the Bison design process took only 7 days.[2] The Bison differs from the baseline Piranha II by raising the height of the roof, removing the turret ring, placing a commander's cupola behind the driver, and incorporating a rail mount system in the cargo/passenger compartment to quickly change mission specific equipment. The driver is seated in the front-left of the crew compartment. The commander has a slightly raised position directly behind the driver with access to his own hatch and mounted machine gun. The engine is to the right of the crew compartment.

The Bison's rail mount system allows it to be adapted to a variety of roles without any major modifications. Bisons used by the Canadian Forces have been adapted for use as armoured personnel carriers (original configuration - mostly replaced in this role by the LAV III), 81mm mortar carriers, ambulances (32), Mobile Repair Team (MRT) vehicles (32), Armoured recovery vehicles (32), Electronic Warfare vehicles (25), and NBC Reconnaissance vehicles (4).