More than six years after Broncos offensive coordinator Adam Gase spent a season in Santa Clara, it appears the 49ers have a strong interest in renewing acquaintances with their onetime offensive assistant. The 49ers are expected to seek a second interview with Gase and make a “final push” to make him their next head coach, NFL Network reported. The 49ers have not had a second interview with any of their head-coaching candidates. …

Meanwhile, the 49ers could have strong interest in Cardinals defensive coordinator Todd Bowles, who interviewed for their head-coaching vacancy Friday. Bowles’ agent, Tony Agnone, said he’s heard the 49ers might bring back his client for a second interview, but a follow-up meeting hasn’t been scheduled. Bowles will have a second interview with the 49ers, CBS Sports reported. …

In the final year of their contracts, two erstwhile backups, 49ers cornerback Perrish Cox and outside linebacker Dan Skuta, were given a gift this past season: an opportunity. For Cox, his chance arrived in the first quarter of the regular-season opener when starter Tramaine Brock exited with a toe injury. For Skuta, his opening came when Aldon Smith was suspended for nine games a week before the season opener. …

After parting ways with the Browns today, unemployed offensive coordinator Kyle Shanahan figures to have a host of job opportunities. And one of those could be with the 49ers, if they name defensive coordinator Vic Fangio their next head coach. Fangio would likely name Shanahan, 35, his offensive coordinator is he’s promoted to head coach, a source said. …

Having Harbaugh withdrawal? If so, there’s good news: Michigan’s Jim Harbaugh will be a part of ESPN’s coverage of the College Football National Championship Game pitting Ohio State and Oregon on Monday, the Detroit Free Press reported. …