More than 100 children have been killed in the Idlib province, dying in their homes, hospitals and marketplaces, according to Aid agencies.

"The Syrian and Russian governments know the exact location of most health facilities and yet they continue targeting them and doctors tell us that the hospitals, which should be the safest places in Idlib, are the exact opposite, they are targets," director of policy at Physicians for Human Rights Susannah Sirkin said.

Russia denies that it is targeting civilians but instead is going after the same kind of extremists that the Western powers have fought off elsewhere in the Middle East.

In the last three weeks, at least four medical facilities have been affected by the violence, as well as a water station serving more than 80,000 people, and several schools, settlements for displaced civilians, markets and bakeries, according to the UN.

The Syrian American Medical Society said many medical facilities have suspended their operations, while some are operating under a state of emergency.

Syrian towns have been reduced to rubble from escalating violence. Credit: PA

Eight water facilities have been attacked in the last two months, diminishing sources of safe drinking water for 250,000 people in southern Idlib.

In the northwest, at least 44 schools have been damaged or destroyed recently, as attacks on educational facilities and personnel have increased.