Curzest for Diabetes

Effective management of diabetes with Curzest

Diabetes can result in various vascular complications such as neuropathy, nephropathy, retinopathy, and cardiomyopathy, which are major sources of morbidity and mortality associated with diabetes. Most of the patients even with well controlled diabetes shall develop these complication with increased duration of disease.

The key pathogenic events underlying the hyperglycemia-associated vascular complications include oxidative stress, inflammation, and associated pathophysiologic pathways. Oxidative stress- induced activation of various cellular pathways and resultant inflammatory episodes contributes to the endothelial damage in the blood capillaries of organs such as the retina, peripheral neurons, and kidneys leading to retinopathy, neuropathy, and nephropathy, respectively.

Unfortunately we don’t have any effective treatment once these complications develop. Prevention of these complications is of utmost importance. However, for prevention we need something that has been shown to be efficacious with no side effects.

Curcumin because of the various actions as detailed in the figure is able to effectively prevent development of microangiopathy and hence development of these complications. In some studies, it has been shown to be effective even in patients who have developed these complications.

References / Research

Curcumin and Diabetes – a systematic review

Curcumin has caught attention as a potential treatment for diabetes and its complications primarily because it is a relatively safe and inexpensive drug that reduces glycemia and hyperlipidemia in rodent models of diabetes…

Diabetic nephropathy is characterized by a plethora of signaling abnormalities. The renoprotective role of curcumin in diabetes mellitus (DM) is highlighted with an emphasis on the molecular basis of this effect…

Therapeutic implications of curcumin in the prevention of diabetic retinopathy

Curcumin has been observed to have therapeutic potential in the inhibition or in slowing down progression of Diabetic Retinopathy (DR). DR is one of the most common complications of diabetes mellitus that affects the blood vessels of the retina, leading to blindness…