Wakulla Springs is internationally known as one of the largest and deepest freshwater springs in the world and the park is host to an abundance of wildlife, including White-Tailed Deer, Alligators, Suwannee River Cooters, Manatees, Wood Ducks, Anhinga, Yellow-Crowned Night Herons, other birds, and snakes. A nature trail offers a leisurely walk along the upland wooded areas of the park.

Daily guided riverboat tours provide a close encounter with wildlife and glass-bottom boat tours are offered when the water is exceptionally clear. Swimming is a popular activity during the hot summer months but the water temperature remains a constant 69 degrees year-round.

The Wakulla Springs Lodge was built in 1937 by financier Edward Ball and is open year-round. Wakulla Springs State Park and Lodge is listed on the Natural Register of Historic Places and is designated as a National Natural Landmark.