Step 2

In preparing the concept, consider the following guidelines regarding study size:

In general, the size of a study should be based on the results of the power analysis carried out and discussed in the statistical analysis section of the project concept. We can help with this based on our project descriptor database.

Under certain circumstances, studies may be deliberately underpowered. Typically these would be studies of interventions that have not been previously tested sufficiently to warrant the resources required for a fully powered trial, but which address particularly significant populations or methodologies.