Gout has been known to mimic many diseases since the time of Hippocrates. Destructive bone lesions from gout may present in an atypical patient, a teenaged patient, a patient with normal uric acid, or in an atypical location in the foot so that the clinician does not include gout in the differential. The association gout with the first metatarsophalangeal joint is so strong that a patient with gout in any other location as the risk of a delay in diagnosis even when the clinical picture is typical of gout. Gout can mimic both a soft tissue tumor or an aggressive bone lesion.

Unicameral bone cyst is a benign lesion of uncertain origin.
It presents in teenagers or young adults.
It presents as an incidental finding or with mild aching pain during sports or running.On MRI the lesion has high signal intensity with minimal loculations or heterogeneity consistent with a fluid filled cavity.
The author of this site recommends that simple treatments with minimal morbidity be tried first, and that more invasive, expensive, and risky interventions be reserved for difficult cases.