Usage & Assay Information

Storage & Safety

General Information

Biological Significance

HIV1 performs highly complex intertwined tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Capsid protein p24 may form the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex.