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There are two (german) threads in DT forum that ensure Assassin's Creed is working fine in vIDE
- without contrary reports.
And be assured we'd have seen many reports if there was a problem with that title/SD version.

One user had problems starting Assassin's Creed in vIDE (link).
The solution was uninstalling DT lite.
Do you have DT lite installed ?

I do have DT Lite installed as well. I'll update this thread presently...

BINGO! Worked like a charm. Thanks Terramex.
Might be a good idea to put this kind of info in the product release notes?!?