A search is underway for a 21-year-old Rice University student who went missing while on spring break in Panama City, Fla., police said today.

Reny Jose was last seen around 7 p.m. Monday after arriving in Panama City on Saturday. His friends contacted the Bay County Sheriff's office Tuesday morning to report him missing from the beachfront home they were renting, authorities said.

Jose's clothing and personal items, including his cell phone, were discovered in a garbage can close to the home, police said, noting the clothes that were discovered were the same clothes he was wearing when he was last seen.