Jeptoo broke away from a group of five runners at the 23-mile mark. Buzunesh Deba finished second with an unofficial time of 2:19:59.

American Shalane Flanagan finished fifth after leading for more than half the race. She took a gamble by setting the early pace. She ran her first mile in 5 minutes, 11 seconds, but fell back on the Newton Hills about 21 miles into the race.