Content

It is a known fact that gabapentin has a significantly higher bioavailability when taken with a meal that is high in lipids. Ease will try to break down the effects of gabapentin with four separate experiences: one without any gabapentin and no fatty meal, no gabapentin with a fatty meal, one with gabapentin but no fatty meal, and another with gabapentin and a fatty meal. The meal itself will vary, but they are all high in lipid content. I have quite a high tolerance, but the effect of eating a meal high in lipids is the same. This experiment was repeated several times, the only difference being the meals.

Section 1 - No gabapentin administered without a meal high in lipids

Amount taken: 0mg

Other drugs consumed: 200mcg melatonin taken around an hour before, 1000mg of hydroxocobalamin

Food consumed: Eloise salad

After eating I felt no effects, restless legs relatively painful. Slept relatively well, likely due to hydroxocobalamin and melatonin supplementation.

Section 2 - No gabapentin administered with a meal high in lipids

Amount taken: 0mg

Other drugs consumed: 200mcg melatonin taken around an hour before, 1000mg of hydroxocobalamin

Felt no effects for around an hour after eating, legs extremely uncomfortable. Felt a threshold drowsiness, most likely due to the large meal I ate. Slept well again, likely due to hydroxocobalamin and melatonin supplementation.

Section 3 - Gabapentin administered without a meal high in lipids

Amount taken: 7500mg

Other drugs consumed: 200mcg melatonin taken around an hour before, 1000mg of hydroxocobalamin

Food consumed: Bowl of tomato soup, light salad

Felt no effects for around a half an hour, then I felt a marked decrease in restlessness. No drowsiness. Did not feel any anxiolysis (decrease in anxiety), just less restless. Slept well, likely due to hydroxocobalamin and melatonin supplementation.

Section 4 - Gabapentin administered with a meal high in lipids

Amount taken: 7500mg

Other drugs consumed: 200mcg melatonin taken around an hour before, 1000mg of hydroxocobalamin

Food consumed: An entire 12 inch cheese pizza

Around a half hour after eating I felt a slight drowsiness, which became more powerful as the night went on, although at no point was it overwhelming like the drowsiness from benzodiazepines and barbiturates. Drowsiness seemed to split into a sedation part as well as a great euphoria. I felt at east, happy, relaxed and amazing. Physical euphoria present as well, it was a comforting warmth spreading throughout my entire body, starting from my limbs. Possible tactile enhancement as well, but significantly decreased libido. Decided to take a bubble bath, warm water felt amazing and relaxing. When I closed my eyes, I had vaguely psychedelic imagery, but it was not very intense. Felt completely at peace. Voice was slightly slurred. The euphoria maintained a steady presence and was a perfect intensity for the entire duration of the effects. After around four hours, I decided to go to bed. No leg pain, and extremely relaxed. Slept very well without a significant hangover the next day. Just as powerful as 4mg of alprazolam, but I did not have the idea of amnesia on my mind at all during the experience and experienced no amnesia at all. Eventually, the closed eye visuals became slightly more formed and vaguely resembled landscapes.

Section 5 - Gabapentin administered with a meal high in lipids, with other depressants

Amount taken: 6000mg

Other drugs consumed: 200mcg melatonin taken around an hour before, 1000mg of hydroxocobalamin, 4 units of alcohol, 0.4mg of tamsulosin (Flomax).

Food consumed: Cheeseburger with fries, some cake.

Was pretty much the same as the previous report (Section 4) but more euphoric and significantly more disinhibited. Closed eye visuals were similar. No tactile enhancement present, modest tactile suppression was there though. Some difficulty urinating, but I was recently hospitalized for urinary retention so it could be because of that.

Conclusion

Eating a meal high in lipids before consuming gabapentin significantly potentiates its effects. The overall experience of gabapentin at those doses is extremely pleasant, with a euphoria not unlike opioids or MDMA. The headspace was a lot like benzodiazepines, very relaxed. Be wary of what you eat when you take gabapentin for recreational purposes.