Office of the Vice Chancellor and Dean

Healing sick and injured people is both an enormous responsibility and honor. Each year at UC Davis Health, we care for tens of thousands of patients and train hundreds of students and residents to be compassionate, skilled caregivers. Our leadership teams are committed to values-based leadership, which includes inclusivity, collaboration and integrity. Together with our talented faculty, students, residents and staff, we are forging new paths in research, health-professional education and patient care.

UC Davis School of Medicineis one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

A national reputation for life-changing biomedical discoveries

A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health

TheBetty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems.Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

Increasing efficiency of practice and revenue

Decreasing practice expenses

Reducing silos and improving integration

Identifying areas to increase quality

Aligning incentives

David H. Wisner is the executive director of thePractice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of theSchool of Medicineandmedical centerto set and achieve joint strategic goals across the health system.

Office of the Vice Chancellor and Dean

Healing sick and injured people is both an enormous responsibility and honor. Each year at UC Davis Health, we care for tens of thousands of patients and train hundreds of students and residents to be compassionate, skilled caregivers. Our leadership teams are committed to values-based leadership, which includes inclusivity, collaboration and integrity. Together with our talented faculty, students, residents and staff, we are forging new paths in research, health-professional education and patient care.

UC Davis School of Medicineis one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

A national reputation for life-changing biomedical discoveries

A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health

TheBetty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems.Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

Increasing efficiency of practice and revenue

Decreasing practice expenses

Reducing silos and improving integration

Identifying areas to increase quality

Aligning incentives

David H. Wisner is the executive director of thePractice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of theSchool of Medicineandmedical centerto set and achieve joint strategic goals across the health system.

Office of the Vice Chancellor and Dean

Healing sick and injured people is both an enormous responsibility and honor. Each year at UC Davis Health, we care for tens of thousands of patients and train hundreds of students and residents to be compassionate, skilled caregivers. Our leadership teams are committed to values-based leadership, which includes inclusivity, collaboration and integrity. Together with our talented faculty, students, residents and staff, we are forging new paths in research, health-professional education and patient care.

UC Davis School of Medicineis one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

A national reputation for life-changing biomedical discoveries

A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health

TheBetty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems.Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

Increasing efficiency of practice and revenue

Decreasing practice expenses

Reducing silos and improving integration

Identifying areas to increase quality

Aligning incentives

David H. Wisner is the executive director of thePractice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of theSchool of Medicineandmedical centerto set and achieve joint strategic goals across the health system.

Office of the Vice Chancellor and Dean

Healing sick and injured people is both an enormous responsibility and honor. Each year at UC Davis Health, we care for tens of thousands of patients and train hundreds of students and residents to be compassionate, skilled caregivers. Our leadership teams are committed to values-based leadership, which includes inclusivity, collaboration and integrity. Together with our talented faculty, students, residents and staff, we are forging new paths in research, health-professional education and patient care.

UC Davis School of Medicineis one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

A national reputation for life-changing biomedical discoveries

A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health

TheBetty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems.Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

Increasing efficiency of practice and revenue

Decreasing practice expenses

Reducing silos and improving integration

Identifying areas to increase quality

Aligning incentives

David H. Wisner is the executive director of thePractice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of theSchool of Medicineandmedical centerto set and achieve joint strategic goals across the health system.

Office of the Vice Chancellor and Dean

Healing sick and injured people is both an enormous responsibility and honor. Each year at UC Davis Health, we care for tens of thousands of patients and train hundreds of students and residents to be compassionate, skilled caregivers. Our leadership teams are committed to values-based leadership, which includes inclusivity, collaboration and integrity. Together with our talented faculty, students, residents and staff, we are forging new paths in research, health-professional education and patient care.

UC Davis School of Medicineis one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

A national reputation for life-changing biomedical discoveries

A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health

TheBetty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems.Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

Increasing efficiency of practice and revenue

Decreasing practice expenses

Reducing silos and improving integration

Identifying areas to increase quality

Aligning incentives

David H. Wisner is the executive director of thePractice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of theSchool of Medicineandmedical centerto set and achieve joint strategic goals across the health system.

Search Releases

Fructose consumption may impact development of metabolic syndrome

Prolonged fructose consumption may contribute to the development of metabolic syndrome, a combination of medical disorders that, when occurring together, increases the risk of developing cardiovascular disease and diabetes.

The findings, just published online in the journal Nutrition & Metabolism, are derived from a UC Davis study that investigated the relative effects of fructose or glucose consumption on 32 older, overweight or obese men and women who consumed glucose- or fructose-sweetened beverages, which provided 25 percent of their energy requirements for 10 weeks.

Consumption of fructose, but not glucose, impacted various parameters associated with metabolic syndrome, including increased circulating concentrations of uric acid, which is known to be higher in people with metabolic syndrome, increased GGT activity, which is an indicator of liver dysfunction, and production of a type of protein known as RBP-4, associated with increased insulin resistance. No previous studies have investigated the effects of glucose or fructose consumption on circulating levels of RBP-4.

The study design involved three phases, including a two-week inpatient baseline period, an eight-week outpatient intervention period, and a two-week inpatient intervention period.

Fasting and 24-hour blood collections were performed at baseline and following 10 weeks of intervention for measurement of plasma concentrations of uric acid, RBP-4 and liver enzyme activities.

The study's first results, published in 2009, showed that visceral adipose volume (fat inside the abdominal cavity) was significantly increased only in subjects consuming fructose, along with increases in several circulating lipids and a decrease in insulin sensitivity, although both groups exhibited similar weight gain.

Senior author Peter Havel, a UC Davis professor with joint appointments in the Department of Molecular Biosciences in the School of Veterinary Medicine and the Department of Nutrition, is currently the principal investigator for a follow-up study comparing impacts of glucose, fructose and high-fructose corn syrup in younger patients. His colleague and collaborator, Kimber Stanhope, directed and coordinated the clinical research study.

Glucose and fructose are both simple sugars, and equal parts of each is the recipe for table sugar (sucrose). The pure glucose and fructose that were used to sweeten the beverages in this study are not found in nature. Most fruits and honey contain comparable amounts of glucose, fructose and sucrose. Grains such as wheat, oats, corn and barley contain large amounts of glucose (and negligible amounts of fructose), but the glucose is packaged as long chains that are called starch or complex carbohydrate.

Co-author Lars Berglund, director of the UC Davis Clinical and Translational Science Center, points out that fruit juices typically feature more concentrated forms of these sugars, while fruits and vegetable contain fiber and other beneficial components.

"It's healthier to eat apples than to drink apple juice," said Berglund.

Other authors include former graduate students Chad Cox, James Graham, Bonnie Hatcher, Steven Griffen and John McGahan, all of UC Davis; Jean Marc Schwarz of Touro University, Vallejo, Calif.; Andrew Bremer of Vanderbilt University, Nashville; and Nancy Keim of UC Davis and the U.S. Dept. of Agriculture, Davis, Calif.

This research was supported with funding from National Institutes of Health (RO1 HL-075675), the NIH's National Center for Research Resources (UL1 RR024146), and the NIH Roadmap for Medical Research. Havel's laboratory receives support from the NIH (HL-091333, DK-097307, and DK-095980) and a Multicampus Award (#142691) from the University of California, Office of the President, and Keim's research is supported by intramural U.S. Department of Agriculture-Agricultural Research Service (ARS) Current Research Information System (CRIS) grant 5306-51530-016-00D.

UC Davis Health System is improving lives and transforming health care by providing excellent patient care, conducting groundbreaking research, fostering innovative, interprofessional education, and creating dynamic, productive partnerships with the community. The academic health system includes one of the country's best medical schools, a 619-bed acute-care teaching hospital, a 1000-member physician's practice group and the new Betty Irene Moore School of Nursing. It is home to a National Cancer Institute-designated comprehensive cancer center, an international neurodevelopmental institute, a stem cell institute and a comprehensive children's hospital. Other nationally prominent centers focus on advancing telemedicine, improving vascular care, eliminating health disparities and translating research findings into new treatments for patients. Together, they make UC Davis a hub of innovation that is transforming health for all. For more information, visit healthsystem.ucdavis.edu.

Office of the Vice Chancellor and Dean

Healing sick and injured people is both an enormous responsibility and honor. Each year at UC Davis Health, we care for tens of thousands of patients and train hundreds of students and residents to be compassionate, skilled caregivers. Our leadership teams are committed to values-based leadership, which includes inclusivity, collaboration and integrity. Together with our talented faculty, students, residents and staff, we are forging new paths in research, health-professional education and patient care.

UC Davis School of Medicineis one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

A national reputation for life-changing biomedical discoveries

A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health

TheBetty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems.Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

Increasing efficiency of practice and revenue

Decreasing practice expenses

Reducing silos and improving integration

Identifying areas to increase quality

Aligning incentives

David H. Wisner is the executive director of thePractice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of theSchool of Medicineandmedical centerto set and achieve joint strategic goals across the health system.