You are in a difficult situation. They do tend to make a lot of noise when they are in heat. The heat cycle does usually last about a week. It may get a little better everyday.

You can give her some Benadryl (diphenhydramine) 1-2 mg per pound of body weight once every 8-12 hours to possibly calm her down and put her in sleep mode. It may also help to isolate her to a bathroom or a small room. If that doesn't work, your veterinarian may prescribe a sedative. If she is making too much noise regardless of what you do, you may want to board her at a veterinary facility until she is over her heat cycle.

This will get better very soon.

Good luck.Please let me know if you have any other questions or concerns.Dr. May