NEET PG MCQs for free – 20 June 2018

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Question 1

Cataract in galactosemia is caused by accumulation of:

A. Sorbitol
B. Galactitol
C. Galactose
D. None of the above

TIPSImportant Question for NEET PG 2019

ANSWER & EXPLANATION

Answer: B. Galactitol

Explanation: Inability to metabolize galactose occurs in the galactosemia, which may be caused by inherited defects of galactokinase, uridyl transferase, or 4-epimerase, though deficiency of uridyl transferase is the best known. Galactose is a substrate for aldose reductase, forming galactitol, which accumulates in the lens of the eye, causing cataract.