A Knoevenagel Initiated Annulation Reaction Using Room Temperature or Microwave ConditionsA. Gilbert CookThe product of a Knoevenagel initiated annulation reaction is identified through a guided prelab exercise of the synthesis of the Hagemann ester, and then through the analysis of GCMS, NMR, and IR spectra. The stereochemistry of the product is determined through the NMR spectrum and Karplus curve, and the student is required to write a mechanism for the reaction.Cook, A. Gilbert. J. Chem. Educ.2007, 84, 1477.

Carbonyl and Conjugate Additions to Cyclohexenone: Experiments Illustrating Reagent SelectivityMichael G. Organ and Paul AndersonUndergraduate students leaving an organic chemistry program should have exposure to these concepts and hands-on experience in dealing practically with the issue of selectivity. In this paper, selective addition of a nucleophile to either end of the enone moiety in cyclohexenone is examined. Organ, Michael G.; Anderson, Paul. J. Chem. Educ.1996, 73, 1193.