Slide 9:

PATHOPHYSIOLOGY :

PATHOPHYSIOLOGY Host defences trigger inflammatory response which lead to clinical syndrome of pneumonia
Inflammatory mediators from macrophages and neutrophils create alveolar capillary leak equivalent to that seen in ARDS.

DIFFERENTIAL DIAGNOSIS :

TREATMENT :

TREATMENT Principles :
Decide according to severity whether the patient is a candidate for outpatient or inhospital treatment
Try to cover organism as per local epidemiological pattern
Keep in mind the drug resistance patterns
IV drugs when hospitalised
Cover for pseudomonas and MRSA when suspected

Slide 21:

Bacteremic Pneumococcal Pneumonia – Dual therapy preferred

Definitive Treatment :

Definitive Treatment What if organism isolated sensitive to Penicillins and we have started with B lactum+Macrolide or Fluroquinolones
What if no response and drug resistant to FQ+Macrolides+Penicillins (MDR)