Review

Aggravation of chronic kidney disease by inflammatory factors; a narrative review on current concepts

1 Department of Epidemiology and Biostatistics, School of Health, Shahrekord University of Medical Sciences, Shahrekord, Iran.2 Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands

Abstract

Chronic kidney disease (CKD) is a common disease worldwide with several causal factors such as inflammation, as one of the most important factors. Inflammation is in turn an outcome of many factors associated to renal dysfunctions like immune dysfunction which could act as a catalyst of many other CKD risk factors. Moreover, inflammation seems to be a logical target for preventive and remedial – general and particular anti-inflammatory interventions – in patients with CKD.