A UFC middleweight title fight between Anderson Silva and Chris Weidman will headline the promotion's annual Independence Day weekend event in Las Vegas.

Silva will look to make his record-setting 11th title defense at UFC 162 on July 6. UFC officials confirmed the bout on Wednesday after Newsday reported it.

Weidman (9-0) assumes the role of No. 1 contender thanks in part to a knockout loss suffered by Michael Bisping in January. Bisping (23-5) had been promised a title shot before the fight, but Vitor Belfort knocked him out in the second round.

A former All-American collegiate wrestler, Weidman hasn't fought since July because of a shoulder injury. He is the No. 2-ranked middleweight in the world, according to ESPN.com, behind only Silva.

Silva (33-4) is coming off a first-round knockout of Stephan Bonnar in a non-title light-heavyweight bout in October. The 37-year-old champion had been linked to potential matchups with Bisping and welterweight champion Georges St-Pierre before drawing Weidman.

The Brazilian is widely considered the best pound-for-pound fighter in the world. His last loss came via disqualification against Yushin Okami in 2006.

Also on the card, middleweight contender Mark Munoz will look to get back in the title conversation when he faces Tim Boetsch.

Munoz (12-3) was ranked among the top two contenders before Weidman knocked him out in the second round on July 11, 2012. He is currently the ninth-ranked middleweight by ESPN.com.

The bout against Boestch will be Munoz's first appearance in the cage since his loss to Weidman.

Boetsch (16-5) suffered his first loss at 185 pounds on Dec. 29, when Constantinos Philippou knocked him out in the third round at UFC 155. The setback also purged Boetsch from the top-10 middleweight rankings. The former light heavyweight had won his first four middleweight fights.

Information from ESPN.com MMA reporter Franklin McNeil was included in this report.