Completion Bonuses:
Successfully complete the game to unlock the hard difficulty setting (enemies at level 50). You can also start a new game with your previous characters at their current experience level.

Play as Deadpool:
Successfully complete the game.

Play as Iron Man:
Find the four homing beacons in Act 1 through 4 and collect the piece of his armor that each set unlocks. Then, save Iron Man after finding the four homing beacons in Act 5.

Play as Professor Xavier:
Successfully complete all Danger Room missions.