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Water pollution is major problem for industries like tannery and textile, because they discharge large amount of wastewater. Adsorption based water treatment plant is a first choice for industrial application. This book describes the different steps for developing an adsorption based wastewater treatment process. Removal of hexavalent chromium from tannery effluent and reactive dyes from textile effluent has been described in this book. This book also elucidates the method of optimization using response surface methodology. A software MINITAB was used for this purpose. Construction and utilization of neural network model has been described in this work. Neural network model was developed using MATLAB. Readers will get a clear idea about the modeling, simulation and optimization of wastewater treatment plant.