This lecture will use case studies from a variety of interesting cases seen in the Neurology Department, relying heavily on videos of each patient’s neurological exam. The signalment and pertinent medical history will be provided before playing the video. After the video, we will discuss the neurological exam findings and practice localizing the lesions to a specific region of the nervous system. Following this, we will discuss differential diagnoses to consider and recommended diagnostics. The patient’s diagnostic test results will then be shared, along with a discussion of the treatment options and prognosis. We will cover a variety of topics covering each major segment of the nervous system.