Agatha Christie: And Then There Were None is the title of a 2005 point-and-click adventure game developed by AWE Productions and published by The Adventure Company for Windows. It was the first in The Adventure Company's Agatha Christie series. The game is a detective murder-mystery; it begins with nine people, including Patrick Narracott, the playable character, who meet and journey to the fictional Shipwreck Island. There, two additional onscreen characters are introduced, and the story then follows the events that unfold.

A Wii version of the game was released in February 2008. It features several motion-sensitive actions, made possible with use of the Wii Remote, such as digging and turning.