Boss Debuff Frame ? Do you mean your targets debuff frame ? The list in the lower right or the buttons on the right of the hud area ? The debuffs for your target should be the list on the lower right with your own debuffs cast on them between the hud and the dashboard along with the cooldown bar. The icons on the right of the hud are your targets buffs.

Which ones in particular do you want to move ? If it's awkward to explain, feel free to throw up a screen shot highlighting the area you want removed.

Some parts of nUI can be moved via the slash commands or the GUI plugin. Others however may be possible via editing of the layout files in the layout folder. If you can't see anything in either of those cases it may not be possible at present to do that.

Sorry, yeah I'm referring to the target debuff frame on the far right-hand side of the screen. Located just above my bags in the attached screenshot. As you can probably imagine it gets quite large during a raid. And, honestly, I never look at it, and would like to have HealBot take up that slot on my resto shaman.

Well, I don't think it was easy to remove those and it would affect your buffs as well as some elements of the hud display as they are currently tied together. However, you could try this plugin (http://www.wowinterface.com/download...raButtons.html) for the auras if its just a space requirement and see if it frees up enough space for your healbot.

I personally put my healbot/grid window directly between the hud and the action bars. Worked wonders for me when I was raid healing on my shammy

YOu can trim that down with something like '/nui maxaurs 25' or the like. If you're dead set on being entirely rid of it, then you'll need to edit [ Interface > AddOns > nUI > Layouts > Default > UnitPanels > {panel mode} > nUI_UnitSkin_{panel mode}Target.lua ] and locate the ["Auras"] section. Find the one that's marked "help" and set "disabled" to false for it.

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What people don't get is that I am, ultimately, an artist at heart. My brush has two colors, 1 and 0, and my canvas is made of silicon.