This is a test of motor coordination and motor learning [1-4]. In addition, it can be used to assess intoxication [5], sedation and strength / stamina [6].

The latency to fall from a rotating rod is scored automatically with infrared sensors in a Rotamex 5 rotarod (Columbus Inst; Columbus, Ohio). Motor coordination can be tested by comparing the latency to fall on the very first trial between treatment groups [7]. Motor learning can also be assessed by comparing the first trial with subsequent trials and is evident as an increased latency to fall over time [3, 4, 8-13].