The NACC Research Structural MRI Database is a large, freely available sample of MRIs that are linked to the standardized
UDS and NP data, as well as genotype data from ADGC.

MRIs at NACC are most appropriately described as a convenience sample of images, voluntarily submitted by several Alzheimer's
Disease Centers. Imaging data collection and acquisition protocols vary by ADC; thus, packages of MRI files at NACC may
include T1-weighted, FLAIR, DTI, T2, or other MR series (and any combination thereof), and subjects may or may not have
multiple scan sessions in the NACC database.

Accessing MRI image files

TO VIEW A SAMPLE OF MRIs meeting specified image and subject criteria:

NACC's MRI query system

Available data:

Researcher requirements:

• Sample size estimation:

– Number of MRI files meeting criteria

– Number of unique UDS subject IDS meeting criteria

Name

Email address

Acknowledgment of NACC's
confidentiality agreement

Visualization software

TO REQUEST IMAGE FILES for analysis and publication purposes:

NACC data file request

Available data:

Researcher requirements:

"Packages" of DICOM MRIs archived by subject ID and MRI date (.zip), delivered via a cloud-based distribution system
and linked to any requested UDS, FTLD, or NP data.

Note: Additional image types not requested may be included in the package.