Production on "Killing Kennedy," which was penned by Kelly Masterson and will be directed by Nelson McCormick, is set to begin in June in Richmond, Va.

"We are thrilled to be working with Rob Lowe, Ginnifer Goodwin and Michelle Trachtenberg, three gifted artists whom have responded to this timely, authentic and entertaining material," Howard T. Owens, president of the National Geographic Channels, said in a statement. "With 'Killing Kennedy,' timed to coincide with the 50th anniversary of the assassination of JFK, National Geographic Channel continues to bring daring, culturally significant television events to our growing global audience."