Police seized three guns and 13 pounds of cocaine worth $500,000 from a Randolph home. Two residents were charged with cocaine trafficking and unlawful firearms possession.

The Norfolk District Attorney’s office says 41-year-old Jose R. Santana and 37-year-old Jessica Ramirez were to be arraigned were to be arraigned on Monday in Quincy District Court.

The arrests capped a four-month investigation.

Authorities say in addition to the cocaine, they seized a .45-caliber pistol, a 9 mm handgun, a .22-caliber rifle with a silencer and other attachments, a half-ounce of heroin, about $80,000 in cash and three vehicles allegedly used in drug activity.

District Attorney Michael W. Morrissey says this appears to be the largest cocaine seizure by state authorities in Norfolk County in several years.