Edinburgh, Roslin and the Birth of Modern Genetics

Main menu

Tag Archives: alan greenwood

Edinburgh holds a number of world records in genetics and animal breeding, which, considering its historic significance in the history of the science in Britain, is not all that surprising. Its most famous ‘first’ is of course Dolly the sheep – the first mammal to be cloned from adult cells – although there are many other examples. However, sometimes the ‘almost firsts’ are just as interesting historically, as well as a little poignant, as I found recently when cataloguing the archive of Alan Greenwood, director of the Poultry Research Centre from 1947 to 1962.

Amongst his wonderful collection of photographs is one depicting a hen standing proudly astride crates and baskets of eggs. The caption informs us that the hen is ‘the sister of the hen which laid 1515 eggs in 9 laying years and shared the world’s record.’ This was intriguing enough in itself, but a full explanation wasn’t forthcoming until I came across two typed pages in Greenwood’s collection of draft lectures and articles. Titled ‘So Near and Yet So Far’, this short piece describes the particularly productive life of the chicken named L1641, ‘from which so little and yet so much more was hoped.’

Part of the research carried out at both the Institute of Animal Genetics and the Poultry Research Centre in Edinburgh was concerned with increasing the productivity and economic value of domestic animals by applied genetics and breeding schemes. In the case of chickens, a large aspect of their value clearly lies in the number and quality of eggs they produce. On 10 April 1939 however, a chicken was hatched at the Institute which would push the limits of egg production beyond the expectations of the staff.

Chicken L1641 (as she was wingbanded) laid her first egg soon after the outbreak of the Second World War. From her first year she was a high producer, laying 273 eggs ‘in spite of wartime stringencies’ as Greenwood wryly tells us. Over the next 8 years she produced on average 142 eggs per year. This is high, although not as impressive as the hens which held world records for the number of eggs laid in a single year. In 1915 a white Leghorn hen in Greensboro, Maryland by the name of Lady Eglantine set a record at 314 eggs in one year. A number of Australorp hens in Australia broke this record successively during the 1920s however, with the number of eggs in one year standing at 347 to 354 to 364!

Where Edinburgh’s chicken L1641 excelled, however, was in the total number of eggs produced over a lifetime. By the time she went into moult in the autumn of 1948, she held the joint world record, which stood at 1515 eggs. However, the strain imposed on her calcified and thickened arteries by the moult was too great, and she died before the end of the year. As Greenwood sadly concludes his article, ‘One more egg only and she would have made history.’

The Alan Greenwood archive contains a variety of material, from degree certificates and correspondence to copies of lectures and scientific papers. However, one of the most fascinating parts of the archive is a collection of photographs which not only contains some nineteenth-century portraits of Greenwood’s ancestors, but also visually documents the work done at the Institute of Animal Genetics Poultry Research Centre from the period Greenwood was director (1947-1962), as well as some earlier photographs from the Institute of Animal Genetics, where Greenwood worked from 1923. The photographs have been mounted on around 100 pages of paper which look to have at one time been fixed inside a folder or album, and are annotated in Greenwood’s hand. The photographs consist mainly of official portraits and photographs taken for publicity and press purposes, informal snaps of conferences and social events and also more personal, intimate pictures of scientists and members of their family. The first page of photographs in the collection is from the latter category, and depicts Polish biologist Stefan Kopeć (1888-1941) and his daughter Maria. When I first came across these pictures whilst cataloguing, I was struck by the intimacy of the shots: Kopeć sits, his spectacles lying on one side, looking frankly at the camera. The second picture shows Maria tenderly embracing her father. I thought these pictures were remarkably domestic and personal for a collection which mainly consists of pictures of scientists ‘at work’, and it piqued my interest in finding out more about Kopeć and his daughter.

It proved to be quite a story. Stefan Kopeć was a pioneering insect endocrinologist, publishing papers in academic journals in Polish, English and German. After receiving his PhD at the Jagiellonian University in Kraków in 1912, he joined the Pulawy Agricultural Research Station in Poland and was made director there in 1929. His most important contribution to science was his discovery of the role of the insect brain in the production of hormones, and this study laid the groundwork for what is now called neuroendocrinology. As for Kopeć’s connection with Alan Greenwood, I was aware that they had published a joint paper, ‘The Effects of Yolk Injections on the Plumage of an Ovariotomised Brown Leghorn Hen’ (Development Genes and Evolution, 121:1-2, 87-95) in 1929-1930, so it seemed likely that Kopeć visited the Animal Breeding Research Organisation (ABRO) at some point around this time. Records in the Institute of Animal Genetics (as the department became known) collection are scanty from this period, but I was delighted to come across a message from Kopeć in the Institute’s visitors’ book dated January 4th 1928, along with another photograph. Kopec writes:

The seven months I spent in the ABRO have been most profitable for me. I gained there some valuable methods and many important suggestions. I was very sorry to have to leave the place where I also got many good friends. Ladies and gentlemen! (both from the laboratories and poultry houses and from the office!) Please accept many thanks for all your kindness, all advice and help and be sure of my gratitude. Do not miss any opportunity to visit me in Pulawy. In the name of myself and my colleagues, of my wife and my F1-generation (♂ and ♀), of my rabbits, mice, fowls and other laboratory creatures I assure you of a very warm welcome…“

The rest of the story, however, is not so positive. In 1940, Kopeć was arrested and imprisoned in Poland by the Gestapo along with his daughter Maria and son Stanislaw for their involvement in a Polish underground university. In 1941, Stefan and Stanislaw were executed at Palmiry, near Warsaw, in reprisal against an action of the Polish underground army.

Stefan’s daughter Maria however, went on to be a distinguished radiation scientist, receiving the prestigious Maria Skłodowska-Curie Medal in 1983, while Stefan Kopeć ‘s name lives on in the annual International Conference on Anthropods the Stefan Kopeć Memorial Conference at the University of Wroclaw.

Photographs like these can have enormous power in the ability to open up individual life stories. Kopeć’s story demonstrates the interrelationship between different collections in the ‘Towards Dolly’ project and reflects the sometimes complex but always fascinating story of animal genetics in Edinburgh.