This is an observational, non comparative, non-randomised, open-label, retrospective, single centre study planned to collect the data of subjects diagnosed with multiple sclerosis (MS) as per Poser or McDonald criteria between 1997 and 2007 in Taiwan. The clinical features and annual relapse rate in the first five years after the onset of disease have been compared between conventional and optico-spinal MS in the earlier studies. This study aims to understand the clinical care pathway of MS subjects and facilitate the subject's diagnosis before converting to MS.

Distribution of locations (medical centre, regional hospital, general practitioners) where subjects were treated for the first episode of attack prior to multiple sclerosis diagnosis [ Time Frame: Data collected for last 10 years between 1997 and 2007 ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

Duration from first attack to confirmation of MS [ Time Frame: Data collected for last 10 years between 1997 and 2007 ] [ Designated as safety issue: No ]

Distribution of MS diagnosis criteria and treatment regimens [ Time Frame: Data collected for last 10 years between 1997 and 2007 ] [ Designated as safety issue: No ]

Annual relapse rate before and after MS treatment [ Time Frame: Data collected for last 10 years between 1997 and 2007 ] [ Designated as safety issue: No ]

Changes in Expanded Disability Status Scale (EDSS) before and after treatment [ Time Frame: Data collected for last 10 years between 1997 and 2007 ] [ Designated as safety issue: No ]

Changes in VEP before and after treatment [ Time Frame: Data collected for last 10 years between 1997 and 2007 ] [ Designated as safety issue: No ]

Association between baseline demographics/disease characteristics and MS [ Time Frame: Data collected for last 10 years between 1997 and 2007 ] [ Designated as safety issue: No ]

Multiple Sclerosis is a chronic, inflammatory disease of the central nervous system (CNS) and is characterised by areas of demyelination, or plaques in the CNS. The disease is twice as prevalent in women as compared to men and causes considerable disability over time and continues for the lifetime of the subject. Subjects with MS are thought to have a genetic predisposition for the disease, though environmental factors such as geographic location and possibly viral infection also play an important role in the process of development of the disease.

OBJECTIVES

Primary objective:

To understand the clinical care pathways of MS subjects at the site over the last 10 years in order to raise the medical attention of MS diagnosis

Secondary objective:

To review the pattern of MS treatment regimens in MS subjects at a particular site between 1997 and 2007

Eligibility

Genders Eligible for Study:

Both

Accepts Healthy Volunteers:

No

Sampling Method:

Non-Probability Sample

Study Population

Subjects diagnosed with MS between 1997 and 2007 in Taiwan

Criteria

Inclusion Criteria:

Subjects diagnosed with MS as per Poser or McDonald criteria between 1997 and 2007

EDSS before treatment was available if subject has started the disease modifying drug treatment.

Contacts and Locations

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Please refer to this study by its ClinicalTrials.gov identifier: NCT01084798