Crataegus Drop (Blood Pressure Reducer)

Red Hawthorn with a set of flavonoids and procyanidins has antioxidant and inotropic positive effects and its primary activity is to increase coronary blood flow and dilate both peripheral and coronary blood vessels leading to its use in angina.

Hawthorn’s positive inotropic action may also be due to inhibition of Myocardial Na+/K+ ATPase and its ability to inhibit the enzyme Phosphodiesterase (PDE) which ultimately results in an increase in intracellular cyclic nucleotides and a subsequent positive inotropic effect. Hawthorn also has Angiotensin-converting enzyme (ACE) which has the ability to regulate blood pressure.

In the largest trial to date, 80 patients with type 2 Diabetes, mean age 60 years, who had DBP(diastolic blood pressure) levels of 85-95 mm Hg, were treated with either Hawthorn extract or placebo for 16 weeks. The patients who were taken Hawthorn had a significant reduction in mean DBP after 16 weeks in contrast with those who were taken placebo(-2.6 vs +0.5 mm Hg, P = .035).

Detailed Specifications

CHF (stage I,II)

Angina pectoris

Hypertention

Drop - 30 ml

Extract of Hawthorn leaves and buds (Crataegus oxyacantha L.)

Initial dose: 60 - 70 drops, 3 times a day for the first 3 - 4 days

Maintenance dose: 25 drops, 3 times a day.

Flavonoids

The primary activity of hawthorn is to increase coronary blood flow and dilate both peripheral and coronary blood vessels leading to its use in angina.

Hawthorn’s positive inotropic action may also be due to inhibition of myocardial Na+/K+ ATPase and its ability to inhibit the enzyme phosphodiesterase (PDE) which ultimately results in an increase in intracellular

cyclic nucleotides and a subsequent positive inotropic effect.

Hawthorn has also to have angiotensin converting enzyme (ACE) inhibiting effect and has the ability to regulate blood pressure.

In the first 3 months of pregnancy, children less than 12 years old, GI illnesses and sensitivity to this drug.

Side effects are seldom reported, if the normal and recommended dose is used. Higher doses can cause.