Home > Press > FEI Announces the Installation of Tecnai Arctica Cryo-TEM at Nanyang Technological University in Singapore: Researchers will combine TEM imaging with XRD and NMR to explore the structure of biological molecules and macro-molecular complexes

Abstract:
FEI (NASDAQ: FEIC) today announced that it has completed the installation of a Tecnai Arctica™ cryo transmission electron microscope (cryo-TEM) at Nanyang Technological University (NTU) in Singapore.

FEI Announces the Installation of Tecnai Arctica Cryo-TEM at Nanyang Technological University in Singapore: Researchers will combine TEM imaging with XRD and NMR to explore the structure of biological molecules and macro-molecular complexes

Hillsboro, OR | Posted on October 25th, 2013

NTU, a young, research-intensive university, is one of the fastest rising universities in Asia. Structural biology and biomedical imaging are key research areas at the NTU School of Biological Sciences and the newly-established Lee Kong Chian School of Medicine. With the purchase of two FEI microscopes, the Tecnai Arctica and Tecnai with iCorr™, the new facility is equipped with industry-leading electron microscopes for single particle analysis and correlative fluorescence imaging.

"Over the past six months, we have built up a new cryo-electron microscopy laboratory at NTU with excellent facilities for high-resolution data collection," said Dr. Sara Sandin, assistant professor at NTU. "The Arctica will enable us to quickly and easily determine the three-dimensional structures of biologically- and medically-important enzymes and macro-molecular complexes. One example is the work being conducted by Professor Daniela Rhodes' group, which involves the study of the structure and function of telomerase, an enzyme that is up-regulated in 85 percent of human cancers."

"The Tecnai Arctica is an industry-leading 200kV cryo-TEM that sets standards in automation, ease-of-use and imaging performance. The system's latest camera, the Falcon II, provides breakthrough imaging capabilities," said Peter Fruhstorfer, vice president and general manager of FEI's Life Sciences Business Unit. "In addition to enabling world-class research at NTU, we expect the Tecnai Arctica's high throughput and ease-of-use to attract a broad range of academic and industrial users to the facility."

The NTU facility installation also includes a Tecnai with iCorr TEM, which integrates a light microscope directly into the TEM column. This unique combination allows fast, easy localization of specific targets in the sample by fluorescence for direct high-resolution analysis of the target's structure by TEM. With cryo-TEM, NMR, XRD, CLEM, image processing and a protein expression platform, NTU has the potential to become a leading center for imaging excellence.

About FEI CompanyFEI Company (Nasdaq: FEIC) designs, manufactures and supports a broad range of high-performance microscopy workflow solutions that provide images and answers at the micro-, nano- and picometer scales. Its innovation and leadership enable customers in industry and science to increase productivity and make breakthrough discoveries. Headquartered in Hillsboro, Ore., USA, FEI has over 2,500 employees and sales and service operations in more than 50 countries around the world. More information can be found at: www.fei.com.

About Nanyang Technological University

A research-intensive public university, Nanyang Technological University (NTU) has 33,500 undergraduate and postgraduate students in the colleges of Engineering, Business, Science, Humanities, Arts, & Social Sciences, and its Interdisciplinary Graduate School. It has a new medical school, the Lee Kong Chian School of Medicine, set up jointly with Imperial College London.

NTU is also home to world-class autonomous institutes – the National Institute of Education, S. Rajaratnam School of International Studies, Earth Observatory of Singapore, and Singapore Centre on Environmental Life Sciences Engineering – and various leading research centres such as the Nanyang Environment & Water Research Institute (NEWRI), Energy Research Institute @ NTU and the Institute on Asian Consumer Insight (ACI).

A fast-growing university with an international outlook, NTU is putting its global stamp on Five Peaks of Excellence: Sustainable Earth, Future Healthcare, New Media, New Silk Road, and Innovation Asia.

Besides the main Yunnan Garden campus, NTU also has a satellite campus in Singapore’s science and tech hub, one-north, and a third campus in Novena, Singapore’s medical district.

For more information, visit www.ntu.edu.sg

FEI Safe Harbor Statement

This news release contains forward-looking statements that include statements regarding the performance capabilities and benefits of the Tecnai Arctica and Tecnai with iCorr. Factors that could affect these forward-looking statements include but are not limited to failure of the product or technology to perform as expected; unexpected technology problems and challenges; changes to the technology; the inability of FEI, its suppliers or project partners to make the technological advances required for the technology to achieve anticipated results; and the inability of the customer to deploy the tools or develop and deploy the expected new applications. Please also refer to our Form 10-K, Forms 10-Q, Forms 8-K and other filings with the U.S. Securities and Exchange Commission for additional information on these factors and other factors that could cause actual results to differ materially from the forward-looking statements. FEI assumes no duty to update forward-looking statements.