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Fibulin 3 ELISA Kits (FBLN3)

On www.antibodies-online.com are 12 Fibulin 3 (FBLN3) ELISA Kits from 5 different suppliers available. Additionally we are shipping Fibulin 3 Antibodies (82) and Fibulin 3 Proteins (13) and many more products for this protein. A total of 120 Fibulin 3 products are currently listed.

The recent finding that a common variant near EFEMP1 was associated with optic nerve-head morphology supports the possibility that the EFEMP1 variant identified in this Primary open-angle glaucoma family may be pathogenic.

Mouse (Murine) Fibulin 3 (FBLN3) interaction partners

The Efemp1 knock-in mice reconstitute the most important histopathologic symptoms of both Malattia leventinese and age-related macular degeneration.

fibulin-3 plays an important role in maintaining the integrity of fascia connective tissues and regulates aging.

both fibulin-3 and -5 are important in maintaining pelvic organ support in mice.

Data suggest a role for fibulin-3 in tissue maintenance and regeneration in the adult olfactory pathway.

Fibulin 3 (FBLN3) Antigen Profile

Antigen Summary

This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.