NFS server and client on separate subnets

I've always kept my NFS server LIF on the same subnet as my NFS clients. Now I have to move the server to a separate subnet across the router from my clients. Generally I run NFSv3 and NFSv4, with RHEL and Linux OS as the NFS clients with hard mounts. Just wondering if others here route their NFS traffic and if there are any general problems you came across.