Abstract

Double neural tube defect is very rare, with only a few cases published in the world’s literature. The embryogenesis of this form of neural tube defects constitutes a complex closure mechanism. The authors here present an unusual case series of 5 cases of double neural tube defects presenting at various levels. The authors emphasizes the need to better understand the molecular basis for neural tube defects .This is probably the third largest series in world literature reported so far. The normal development and rationale preceding such defects are also discussed.