Adrenal Gland, Cortex - Hypertrophy - Gallery

Adrenal gland, Cortex - Hypertrophy in a female Sprague-Dawley rat from a chronic study. There is a well-demarcated, noncompressive focal area in which the cells are enlarged (FH). C = cortex, M = medulla.

Adrenal gland, Cortex - Hypertrophy in a female Sprague-Dawley rat from a chronic study (higher magnification of Figure 1). The cells in this focus of hypertrophy (FH) have increased amounts of pale eosinophilic cytoplasm.

Adrenal gland, Cortex - Hypertrophy in a male B6C3F1/N/N mouse from a chronic study. There is a focus of enlarged cells (arrows) in the cortex that slightly compresses the adjacent parenchyma; there is also subcapsular hyperplasia (SCH).

Adrenal gland, Cortex - Hypertrophy in a male B6C3F1/N/N mouse from a chronic study (higher magnification of Figure 3). The cells in this focus of hypertrophy (FH) have increased amounts of pale eosinophilic cytoplasm and slightly enlarged nuclei.