Bronopol is used in consumer products as an effective preservative agent, as well as a wide variety of industrial applications (almost any industrial water system is a potential environment for bacterial growth, leading to slime and corrosion problems - in many of these systems Bronopol can be a highly effective treatment). (wikipedia.org)

It is used in a number of manufacturing processes as a high value specialty chemical including the electronics industry, flavors and fragrances industry, specialty solvents, polymer crosslinking, and pharmaceutical industry. (wikipedia.org)

Additionally, the use of spectroscopic techniques (circular dichroism (CD) and fluorescence) and differential scanning calorimetry (DSC) was identified as common techniques used in evaluating an antimicrobial preservative for its impact on the conformational stability of peptide, protein, and vaccine antigens. (pharmaguideline.com)

Their efficacy as preservatives, in combination with their low cost, the long history of their use, and the inefficacy of some natural alternatives like grapefruit seed extract (GSE), probably explains why parabens are so commonplace. (wikipedia.org)

Owing to its low mammalian toxicity (at in-use levels) and high activity against bacteria (especially the troublesome Gram-negative species), bronopol became popular as a preservative in many consumer products such as shampoos and cosmetics. (wikipedia.org)

Due to complaints of mold found in the 30 mL bottles after use, concerns regarding the effectiveness of the preservative after use and handling of the product by consumers have prompted the recall. (drugs.com)

A product whose preservative may not be effective could lead to the use of a contaminated product which creates a potential risk for eye infection. (drugs.com)

Gustav Sotek, "N,N-bisfurfuryl-2-furylmethanediamine, its production and use in pharmaceuticals", World Patent 8704160 (1987) Charles F. Winans (1939). (wikipedia.org)

The same month, Teva announced the ¥40 billion purchase of a majority stake in Japanese generic drug company Taiyo Pharmaceutical Industry, a move to secure a Japan-local production facility. (wikipedia.org)

IPEC works in collaboration with ExcipientFest to present topics ranging from regulatory affairs to research and development, often featuring speakers from FDA and other pharmaceutical organizations. (wikipedia.org)

During the 1930s, new immigrants from Europe founded several pharmaceutical companies including Teva ("Nature" in Hebrew), Assia, and Zori. (wikipedia.org)

In 1976, these three companies merged into the modern-day Teva Pharmaceutical Industries Ltd. In 1980, Teva continued to follow its vision of becoming one of the world's biggest pharmaceutical companies by acquiring Ikapharm, then Israel's second largest drug manufacturer. (wikipedia.org)