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In a study of 254 women suffering from hyperemesis gravidarum, adverse pregnancy outcomes including premature births and low birth weight babies were associated with antihistamine use, according to a six-year study in the European Journal of Obstetrics & Gynecology and Reproductive Biology. Researchers noted that such medications were effective in less than 20% of the users.

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Prenatal exposure to metoclopramide was not linked to an increased risk for major congenital defects, stillbirth or miscarriage, according to a Danish study in the Journal of the American Medical Association. The use of the nausea medication during pregnancy was also not tied to any secondary adverse outcomes, including premature birth and low birth weight.

In a study of 254 women suffering from hyperemesis gravidarum, adverse pregnancy outcomes including premature births and low birth weight babies were associated with antihistamine use, according to a six-year study in the European Journal of Obstetrics & Gynecology and Reproductive Biology. Researchers noted that such medications were effective in less than 20% of the users.

Researchers found that women who experienced hardships during adolescence are more likely to have pregnancies that result in preterm births or babies with low birth weight during adulthood. Further studies are needed "to specify pathways between childhood adversities and reproductive health outcomes and to evaluate protective factors that could help to alleviate long-term influences of early adversity," the researchers said.

Researchers found that women who experienced hardships during adolescence are more likely to have pregnancies that result in preterm births or babies with low birth weight during adulthood. Further studies are needed "to specify pathways between childhood adversities and reproductive health outcomes and to evaluate protective factors that could help to alleviate long-term influences of early adversity," the researchers said.

Hyperemesis gravidarum can turn pregnancy bliss into a nightmare, causing chronic nausea, vomiting and weight loss, which can lead to dehydration and malnutrition. Journalist Tomoeh Murakami Tse, who relates her experience with the condition, says that while the cause is not known, hormones and genetics are suspected to play a role. Hyperemesis gravidarum also may affect fetus growth.