CAS Number

56796-39-5

Molecular Formula

C15H16N7O5S3Na

Molecular Weight

493.52

Mechanism of Action

Like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases.

Storage Conditions

-20°C

Tariff Code

2941.90.3000

Spectrum

Cefmetazole is broad spectrum antibiotic targeting a wide range of Gram-positive and Gram-negative bacteria. Cefmetazole is more potent against many Gram-negative enteric flora and pathogens than other first generation cephalosporins.