The story centers on a sophomore named Kanako who is allergic to men to the point of breaking out in hives any time she comes in contact with one.
She enrolls in the same all girls school where her own parents met, Ame no Kisaki, because she wants to find her destined yuri (lesbian) partner. She meets a captivating freshman named Mariya who fits her criteria — except her seemingly ideal mate happens to be a cross-dressing sadistic boy.