It starts on the B215 Peckham Hill. It originally ran along Bullar Close but its start has now been moved one block north to Commercial Way, although not all maps agree.

The B216 soon turns left at a set of traffic lights onto Peckham Park Road to rejoin original route. It heads northeastwards along this straight, residential road and ends less than half a mile later at traffic lights on the A2 Old Kent Road.