1

Not all swelling bad:
Swelling in the hands in the morning, or swelling in the feet in the evening is often due to water retention, and is harmless. Avoiding excess salt, and using support hose can help. Persistent swelling that is localized to joints, or associated with redness, warmth, or tenderness may be signs of arthritis.
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4

Neuropathy:
It is possible. However blotchy prickly hands or feet with hot sensation are not specific findings of a particular disease. Other conditions like raynaud phenomenon or autonomic nervous system dysfunction or neuropathy can cause this presentation. Consider checking your sugar and vitamin B12 levels. Please check with your physicians for proper diagnosis and treatment. I hope you feel well soon.
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6

Some advice:
Location of problem either right brain, or high cervical spinal cord, and could be seen with an ms plaque, lupus cerebritis or even stroke activity secondary to diabetes. Steroids could reverse, but might cause major elevation in blood sugar (acthar might be easier). Have your doc check your meds, and eliminate any med that specifies anti-tnf-alpha activity. Make certain good vit d levels.
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7

Decreased oxygen:
With the rsd, lupus and chronic edema this would naturally lead to some kind of compromise of blood flow to the feet. When the blood flow is diminished, this will decrease the amount of oxygen to the feet and hands while building up Lactic Acid that leads to your charlie horses/cramps. See your doctor for treatment options.
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10

Depends on many :
this depends on many things. We do not know your age, the manifestations of your lupus, the medications you take, but sweats could be related to the lupus or could be related to infection. You need to discuss this with your physician and make sure that you are fully evaluated for your care
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11

Question?:
I am not sure what you are asking. The ANA is a screening test for lupus but can be seen in numerous other diseases and in people who have no disease. I assume the lupus test you mention is a dna antibody. This test does not have to positive to have lupus. Finally, about 30% of lupus patients also have fibromyalgia. See a rheumatologist if you have not done so already.
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12

Sounds like FM:
ANA is often "positive" but not clinically useful until it gets to positivity at 1:320 or 1::640 level. Diagnosis of lupus would have to have a compatible clinical syndrome first and supporting labs tests second. Your symptoms sound more typical of fm than sle.
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13

Yes due to FALSE NEG:
Every test in the world has a FALSE NEGATIVE rate which tells what percentage of the time a test comes out negative but really it should say positive. It is rare for someone to have RA, LUPUS, or FM and have a positive ANA.... on the order of much less than 1%. will be FALSE NEGATIVE.
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18

Heel pain:
If I want to take a guess with this little information I would say you might suffer from Plantar fasciitis, the inflammation of heel Tendon, but there are other possible causes too, please see your provider for further evaluation.
Heel pain is not uncommon in Lupus.
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19

The question?:
If you are asking about the treatment option, her rheumatologist would be in the best position to give the answers. Fortunately most LE cases can be controlled. This is a rather unusual presentation for Lupus and thus the diagnosis should be confirmed by a rheumatologist.
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20

Depends on your data:
This depends on the database to diagnose your lupus. These symptoms suggest neurologic issues but you need to discuss with your physician and your rheumatologist. It could also be soft tissuerheumatism. This may not signal a flare at al. Your physician can guide you
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