We previously reported the plausible mechanism for the bioavailability enhancement of Coenzyme Q10 (CoQ10) which includes the enzymatic degradation of γ-Cyclodextrin (γ-CD) out of CoQ10 - γCD complex with the aid of sodium taurocholate (NaTC) in small intestine 1),2),3).
In this study, the influence of NaTC on the enzymatic degradation of non-complexed γCD and γCD out of Curcumin - γCD (Cur - γCD) complex were investigated to demonstrate the previous presumption.