1Department Of Internal Medicine, St. Paul’s Hospital, The Catholic University of Korea, 130-709 - Seoul/KR

2Department Of Internal Medicine, The Catholic University of Korea, 130-709 - Seoul/KR

Abstract

Several novel animal models for lung cancer have been developed in recent years. Cancer mouse models by exposure to various carcinogens are still commonly used tumor mouse models. Benzo(a)pyrene (B[a]P) is one of the major environmental pollutants and induces carcinogenesis specifically targeting the lung. The aim of this study is to establish a standard design of mouse models for lung cancer following B[a]P exposure method.