Avascular Necrosis Overview

Avascular necrosis is a localized death of bone as a result of local injury (trauma), drug side effects, or disease. This is a serious condition because the dead areas of bone do not function normally, are weakened, and can collapse. Avascular necrosis ultimately leads to destruction of the joint adjacent to the involved bone. The hip is the most common joint affected by avascular necrosis, followed by the knee, shoulder, ankle, elbow, and wrist.

Avascular necrosis is also referred to as aseptic necrosis and osteonecrosis.