Anthrax Lethal Factor Antibody (MA1-41075)

Performance guaranteed

Purchase with confidence, knowing that we stand behind
the performance of our antibodies with the InvitrogenTM
antibody performance guarantee. If an InvitrogenTM antibody
doesn't perform in your experiment as described on our website
or datasheet, we'll replace the product at no cost to you, or
if you prefer, we'll provide you with a credit for a future
purchase.*
Learn more.

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Tested Applications

Dilution *

Western Blot (WB)

0.1-1 µg/ml

* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the
product for use in their own experiment using appropriate negative and positive controls.

Product Specific Information

Suggested positive control: recombinant protein.

Background/Target Information

Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxicity to occur. It begins with the binding of PA to its cell-surface receptor, ATR (Anthrax Toxin Receptor), at which point PA is cleaved and the resulting 63 kD carboxyl-terminal fragment binds to LF and EF. LF is a protease that is known to cleave members of the mitogen-activated protein kinase kinase (MAPKK) family2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.