Mark Laufer, chief of gynecology at Children's, reported on 129 adolescents with surgically diagnosed endometriosis treated with norethindrone acetate from 1992 to 2010 by one gynecologist at a single children's hospital.

The agreement also would settle litigation between the two companies over Galen's femhrt hormone therapy and Estrostep oral contraceptives (both containing norethindrone acetate and ethinyl estradiol).

Various hormonal regimens were used in these studies, including conjugated equine estrogen (CEE) alone, CEE plus medroxyprogesterone acetate, CEE with trimegestone, estradiol-17[beta] with trimegestone, and estradiol-17[beta] with norethindrone acetate.

Various hormonal regimens were used in these four studies, including conjugated equine estrogen (CEE), CEE plus medroxy-progesterone acetate, CEE with trimegestone, estradiol-17[beta] with trimegestone, and estradiol-17[beta] with norethindrone acetate.

As my coauthors and I pointed out in our article, postoperative suppression with norethindrone acetate, continuous hormonal contraception, or a levonorgestrel intrauterine device is an essential component of long-term management of endometriosis.

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