A Special Issue dedicated to the International Workshop Infinity-2010 "Infinite and Infinitesimal in Mathematics, Computing and Natural Sciences" held in Cetraro, Italy, 17–21 May 2010, has been published in the ELSEVIER international journal Applied Mathematics and Computation, volume 218, Issue 16, Pages 7977-8216 (15 April 2012) (Guest Editors: Renato De Leone, Yaroslav Sergeyev, and Anatoly Zhigljavsky).