Bottom Line:
Bioinformatics analysis using Panther revealed that the 38 proteins associated with TCs represented cellular functions such as intercellular communication (via vesicle mediated transport) and structure morphogenesis, being mainly cytoskeletal proteins and oxidoreductases.In conclusion, we report here the first extensive comparison of proteins from TCs and ECs using a quantitative proteomics approach.Moreover, they might inhibit the oxidative stress and cellular ageing and may have pro-proliferative effects through the inhibition of apoptosis.

fig07: Bar graph representation of the distribution of identified proteins in TCs and ECs (cell culture, 10th day) according to their protein class (A and B), pathways (C and D) and cellular components (E and F) classification.

fig07: Bar graph representation of the distribution of identified proteins in TCs and ECs (cell culture, 10th day) according to their protein class (A and B), pathways (C and D) and cellular components (E and F) classification.

Bottom Line:
Bioinformatics analysis using Panther revealed that the 38 proteins associated with TCs represented cellular functions such as intercellular communication (via vesicle mediated transport) and structure morphogenesis, being mainly cytoskeletal proteins and oxidoreductases.In conclusion, we report here the first extensive comparison of proteins from TCs and ECs using a quantitative proteomics approach.Moreover, they might inhibit the oxidative stress and cellular ageing and may have pro-proliferative effects through the inhibition of apoptosis.