GREMLIN Results:
Residue pairs sorted by strength in covariance:Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

i

j

Raw Score

Scaled Score

4_T

54_L

0.82842

3.099

4_T

51_R

0.7972

2.982

16_E

55_H

0.70387

2.633

51_R

54_L

0.65334

2.444

17_A

47_G

0.65229

2.440

16_E

56_K

0.59208

2.215

18_A

55_H

0.50904

1.904

18_A

59_D

0.46034

1.722

16_E

52_P

0.35626

1.333

55_H

59_D

0.34353

1.285

47_G

58_F

0.3354

1.255

14_L

52_P

0.33145

1.240

44_P

47_G

0.30606

1.145

14_L

62_L

0.30061

1.124

52_P

56_K

0.28485

1.065

26_G

29_W

0.28396

1.062

13_E

62_L

0.28179

1.054

15_L

23_F

0.27912

1.044

59_D

65_I

0.27681

1.035

14_L

56_K

0.27579

1.032

8_D

13_E

0.27065

1.012

26_G

30_M

0.26947

1.008

54_L

63_F

0.26456

0.990

18_A

23_F

0.26338

0.985

20_I

46_N

0.26177

0.979

2_V

14_L

0.25705

0.961

22_P

61_G

0.24691

0.924

56_K

60_R

0.24533

0.918

15_L

49_L

0.2448

0.916

21_V

61_G

0.24217

0.906

58_F

61_G

0.23674

0.886

19_H

55_H

0.23478

0.878

5_G

17_A

0.23291

0.871

20_I

58_F

0.23203

0.868

23_F

61_G

0.231

0.864

21_V

26_G

0.23042

0.862

3_I

65_I

0.22862

0.855

8_D

65_I

0.22705

0.849

21_V

30_M

0.22136

0.828

53_D

62_L

0.21764

0.814

14_L

57_L

0.21094

0.789

7_R

15_L

0.20785

0.777

49_L

59_D

0.20489

0.766

17_A

61_G

0.20395

0.763

20_I

48_L

0.20304

0.759

3_I

62_L

0.20039

0.750

60_R

63_F

0.19916

0.745

16_E

29_W

0.19798

0.741

47_G

61_G

0.19132

0.716

7_R

20_I

0.19088

0.714

26_G

44_P

0.1888

0.706

2_V

8_D

0.18845

0.705

2_V

5_G

0.18617

0.696

20_I

64_A

0.18031

0.674

6_I

43_S

0.17909

0.670

12_W

45_S

0.17652

0.660

3_I

54_L

0.17576

0.657

21_V

64_A

0.17341

0.649

12_W

43_S

0.17293

0.647

54_L

57_L

0.17247

0.645

2_V

49_L

0.1705

0.638

25_L

29_W

0.17014

0.636

26_G

43_S

0.16464

0.616

14_L

53_D

0.16432

0.615

57_L

62_L

0.16399

0.613

25_L

30_M

0.16371

0.612

8_D

12_W

0.16323

0.611

21_V

25_L

0.16314

0.610

15_L

61_G

0.16209

0.606

24_S

31_N

0.15984

0.598

15_L

57_L

0.15795

0.591

7_R

13_E

0.15658

0.586

49_L

53_D

0.15418

0.577

21_V

29_W

0.15394

0.576

Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.

HHsearch Results:
Top (length/2) GREMLIN results overlayed on top 10 PDB hits: Legend: The grey circles underneath are pdb residue contacts (min distance < 5 Angstroms). The coloring of these circles is based on HHsearch results which uses the overall probability, per-site alignment prob and agreement of top hits weighted by HHsearch score (Note we only consider monomeric contacts, there might be homo-oligomeric contacts in the pdb that are not shown.)