On Sunday, the former Alaska governor's targeted House Speaker Paul Ryan when she publicly vowed to help unseat her fellow Republican as revenge for his bombshell refusal to endorse Trump's nomination.

"His political career is over but for a miracle because he has so disrespected the will of the people, and as the leader of the GOP, the convention, certainly he is to remain neutral, and for him to already come out and say who he will not support is not a wise decision of his," Palin told CNN's Jake Tapper.

Palin said Ryan, who stands second in order of succession to the presidency after Vice President Joe Biden, needs to be "Cantored, as in Eric Cantor," who was the Republican House majority leader whose 2014 primary loss in Virginia served as the Tea Party's shot across the bow of the party's mainstream.

Palin said she believes Speaker Ryan wants Trump to lose in order to better his own chances in a 2020 presidential run.

Ryan, Congress's Republican standard-bearer, sent shockwaves through the party last week when he said Trump had not yet earned his endorsement.