Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Description: GCKR, also known as KHS for kinase homologous to SPS1/Ste20, is a KHS protein kinase. GCKR is an upstream activator of the stress-activated protein kinase (SAPK) signaling pathway, and its activity has been shown to increase in response to tumor necrosis factor (TNF), TNF receptor-associated factor 2 (TRAF2) and UV light. In primary B cells, GCKR has been shown to be activated by CD40.