Medicinal and aromatic plants have gain new attention in the past years due to their content in bioactive compounds and recognized health-promoting effects. One of the most important herb known is Salvia officinalis L., rich in essential oils, phenolic compounds and vitamins. Also, it has several uses and medicinal impacts (e.g. antibacterial, antiviral, anti-oxidative, anti-inflammatory, antidiabetic and antitumor activities). Hence, the aim of this work is to review the literature on ecology, cultivation, composition and utilization of Salvia officinalis L. a standard literature search was performed using several electronic databases for identification of peer-reviewed articles. Medicinal and aromatic plants are a very important resource for the people for two reasons: They have contributed to the prosperity of the people through the health care program, and as a source of income derived from production of raw materials.