Ann McKee

Dr. McKee completed her undergraduate studies at the University of Wisconsin and received her medical degree from the Case Western Reserve School of Medicine. She completed residency training in neurology at Cleveland Metropolitan General Hospital and fellowship training in neuropathology at Massachusetts General Hospital. She was Assistant Professor of Neuropathology at Harvard Medical School until 1993, and is currently Professor of Neurology and Pathology at Boston University School of Medicine. Dr. McKee is the Chief Neuropathologist for VA Boston Healthcare System, and director of the CTE Center and Neuropathology Core for the Boston University Alzheimer’s Disease Center (BUADC). Dr. McKee is also associate director of the BUADC. Dr. McKee directs multiple brain banks including those for the BUADC and Framingham Heart Study which are based at the Bedford VA, and the VA-BU-CLF and Chronic Effects of Neurotrauma Consortium brain banks which are based at VA Boston. Dr. McKee’s research focuses on CTE and the late-effects of traumatic neurodegeneration.

Research Interests

Dr. McKee’s research interests center on the neuropathological alterations of neurodegenerative diseases, with a primary focus on the role of tau protein, axonal injury, trauma, vascular injury, and neurodegeneration. Much of her current work centers on mild traumatic brain injury from contact sports and military service and its long-term consequences. As a board-certified neurologist and neuropathologist, she is particularly interested in the clinical, behavioral and psychological manifestations of pathological disease and the neuroanatomical localization of clinical symptoms. She has written widely on many neurodegenerative diseases including Alzheimer’s disease, Lewy Body disease, Parkinson’s Disease, Progressive Supranuclear Palsy, Multiple System Atrophy, Frontotemporal Degeneration, Corticobasal Degeneration and Chronic Traumatic Encephalopathy (CTE). She has been an invited participant in several NIH-sponsored workshops on Progressive Supranuclear Palsy, Vascular Dementia and Traumatic Brain Injury. Dr. McKee’s work has been essential in establishing the clinical and pathological spectrum of trauma induced neurodegenerative disease, including CTE and Chronic Traumatic Encephalomyelopathy.