In high school me and my girlfriend snuck down to my parents beach house a week or two before summer started with a shit load of shrooms. The day was pretty pedestrian at first, so we decided to take more than we ever had before and proceeded to get naked and run around the house having a hilarious time...then we hear the front door open. We didn't think anyone was coming down so we, logically, assumed it was a break in and decided to hide in the shower. Turns out it was my grand mom and all her old lady friends coming down for a beach day. They found us (naked and nearly in tears) and my grandma just assumed we snuck away to bang so she was like "I won't tell your parents, you're just being kids, but you have to come to lunch with us." Lunch with 4 old women while tripping balls was not ideal to say the least.

also, grandparents have a very different perspective and attitude than parents.

Grandparents want all of the fun things associated with children and none of the burdensome responsibilities. Grandparents do not want to raise the grandkids. They just want to hang out and relax and enjoy the company. They're not gonna break your balls.

Yeah this was my grandma! She only ever got on me about something if it was bad. Even then it would just be a brief "hey just don't do that. Your mom would kill me if she found out."

She even actually let me and my boyfriend sleep in the same room together when we had first met (long distance, still together happily.) She is definitely one of the reasons that our relationship has lasted all this while, even though she just died last year. I have endless thanks and gratefulness for that woman, and I hope she isn't too mad about all the drugs I've been doing in my off time.

They already dealt with your parents' shenanigans back when they were young and probably saw them turn out fine. And life's too short anyway, might as well have quality time with family whenever possible.

My grandads both died before I was born so don't really know what I missed there.

My man on my mother's side had Alzheimer's for my whole life, and lived in Sydney while I'm in Melbourne my whole life so never saw her and when I did there was no connection because she never knew who I was.

My nan on my dads side was the only grandparent I ever knew, and she never really liked me, because my father isn't my biological dad but raised me. She didn't really like that.

Kinda sucks not having grandparents, that's why I wanna be that really fucking awesome dad and grandfather someday because I want to give them what I missed out on.

When I was 16 my parents were going out of town so my mom calls my grandmother and asks if I can stay with her for the week because my mom thought I was going to throw a party. Without missing a beat my grandmother goes "what am I gonna do with a house full of 16 year olds?". Mom had to explain it was to prevent me from throwing a party but I love that my grandma was so ride or die it never crossed get mind that I wouldn't be throwing that party.

My friends and I decided to do acid and go mingle with drunk people at the college bars. We began talking to some drunk guy in the closed off street for awhile, but his face started to freak me out and I said, "sorry we have to go. Your face is melting." I thought it was honestly just the acid, having done it tons of times before, until I looked at my friends. They were mortified. Apparently the guy we were talking to had horrible chemical burns on his face and I wasnt hallucinating it.

Speaking of Hell, my dad told me about the time he had been clean from acid for two weeks, long enough for it to get out of his system. He goes into his bedroom, and there are demons dancing on his bed. He prays to God and they vanish. He finds Jesus a week later. This was in the early 70's, mind you.

Fast forward to the 80's. The folks don't let us see any really scary movies, so I hear all the kids at school talking about Freddy Kruger and Jason and Gremlins, but I never get to see any of them. 1990, The Gremlins 2 ad shows up on TV, and Dad does not laugh at their antics. I notice, I remember, but I don't really pay it any mind.

Mid-90's, I'm listening to his stories of the 70's and his drugged-up misadventures. He tells me about the demons dancing on his bed. Then he says something I've never forgotten. "Gremlins." Wait, what? "Gremlins, like in that movie. They looked just like them. Identical."

I have two possible explanations, and both are frightening: acid allows true perception of deeper reality including demons, or both my dad and the designer for Gremlins had the same bad trip. Either way, that scared me away from recreational drugs forever.

Oof. I had a similar experience with some friends in a park in Brooklyn.

A big friendly dog, a gold Lamborghini, and 6 African American men were part of a photo shoot going on in the park (this is common for hipster Brooklyn). One photo involved ski masks. Two of my friends (also tripping) turned around at the wrong time, didn’t see the dog, car, or camera, and instead saw 6 African American men putting on ski masks in unison. They screamed “get down” at the top of their lungs and started running. I eventually caught up to them huddled behind some rocks and convinced them everything was OK but by then the whole park was staring at us in awe of our racism. Being a small park by the water, the only way out was passing within 10 feet from all offended parties. Not a great day.

I only did acid once, around 1990. I was with a bunch of friends, one of whom I was convinced was turning into a lizard because she seemed to have scaly skin on her leg. I always assumed the scaly "lizard effect" was due to the acid.

Anyway, I told this "hilarious" story to her husband some 20 years later and he came really close to punching me. It turned out she has had chronic psoriasis since she was a kid. It comes and goes and hits in patches. It's been a real burden for her and she's a super nice person who's never been anything but nice to me.

One of my friends put it perfectly: when you are on acid, you see the flesh in people's faces, not the face. That's why you shouldn't look in the mirror either, or you'll freak out about all your "imperfections" (if you are that kind of person, I looked at the mirror and just realized how old I looked... never crossed my mind I was "an adult")

It was always a last resort. As a shot out junkie I used to spend hours and hours trying to find a vein. I have shot dope in veins on my feet, legs, torso, neck and even the palms of my hands because I was so desperate to get a shot off and get well. The times I shot up in my dick, I would literally be covered in blood all over my body trying to hit all my "go to" veins but nothing worked so out of pure desperation I would see the vein on my dick and just go for it to get well.

Ah, so that's where all the random dried blood smudges come from. I didn't think of that. I work with lots of patients who are IV drug users, and one of the first things we do when we admit them to ICU is give them a quick 'bath' with what are essentially beefy diaper wipes (we call them bath wipes). Many IVDU always have that thin layer of blood smeared everywhere (especially their hands, which are really hard to clean properly), and I'm always confused, because there's never a big wound or obvious trauma. Now I know where it comes from.

First you develop scar tissue that starts to make it harder to inject on one place. Then you find new place. The vein starts to get inflamed, almost no matter how well you keep things clean, the substances can be acidic or base, they have irritants, dust and of course, bacteria. Best and easier places go first of course and you need to switch to different vein. Depending on the substance, it can get painful faster and you see less collapsed veins because you need to switch places all the time. Some use cycles to keep their veins from getting too bad, some stick to same hole until it is pussfilled festering hole. With heroine, we are also looking at a strong painkiller and very strong physical dependency, general apathy towards one's own health and simple self-harm. I used to be hooked on amphetamines, (not meth allthough there is no guarantee what i actually took) and i have permanent marker on my arm in a form of some scarring. I didn't go real bad, that was my first real warning sign when the needle didn't go in anymore and i had to switch arms. I kept very meticulously things clean, most of the time so i didn't have lots of pains, nor inflammation. I survived without contracting Hepatitis C (edit.) when pretty much everyone else around me had very aggressive version of it, over 80% of that group got it during that one year.. Heroin is the worst and there we see more collapsed veins and generally not caring that your arm has a gaping hole and it stinks. One of the main reasons is the stuff itself and how it is not controlled by anyone, they are left with all kinds of very, very nasty chemicals, solvents, acids and bases in a hurry to get it out of the door fast.

Tried it once, stopped right then and there. I literally said "this is too good. I don't care if this building dropped on me". You just don't care if you die, seeing all those wonderful dreams.. Scary, really. It is definitely on my list for deathbed medication though exactly for that reason.

If you read closely, that did not stop me from becoming a junkie anyway, my poison of choice just was different, that's all. One thing that definitely saved the group of people i was hanging out with from getting even worse was that heroin was banned by local dealers consortium, it was very strict and very real policy that just was not crossed. So excluding rare single doses or one day's worth for 5 people once a year, there just wasn't any around. The ban wasn't for the goodness of their heart (although, i have to say, that played some significance too), it was just good business to keep the "real" junkies away. I've done other opiates and i do not like who i become; stealing from friends kind of asshole. So i try to stay away from that and pretty much from anything but weed and even that is not the strongest kind.. which is the only drug i can recommend, good old weed and not talking about super extracts or even buds. Weed, the beer of cannabis ;)

It happens to people who are hospitals a lot. My mom's best friend's daughter was disabled and always in and out of the hospital getting blood taken or whatnot eventually it got to the point where they couldn't find any 'good' veins to tap into.

Someone went into way better detail and we're actually correct before me ( I would assume) I'd just like to let you know it doesn't mean you're a drug addict.

I dated a girl who lit up the room with her smile, and was wonderful to be around. Her coworker gave her a few free lines of coke, then offered to start selling it to her.

Within a month, she owed him most of her paycheck by the day she got paid. She'd call me up, crying, because it had been a half hour since she'd done coke and she already couldn't handle the need for more.

I broke up with her, but would see her randomly at club nights or concerts for years...but I never saw her smile once in that time. Coke broke her as a person.

I've done salvia a number of times (chewing method, not smoking) and it was awesome. One time the words in my chat program were protruding out of the screen and (of course) would vanish when they hit the top of the screen. I kept spamming my friends on IRC asking "who owns the box?" (my monitor) "where do they go??" and saying "we need to let them be free instead of trapping them in the box".

Another time, I closed my eyes for about 15 seconds and in that span, I was inside the original Mario Bros. video game for the NES and it went in super-super-super-fast-forward and I beat the game as Mario and still understood every bit of every level.

Still another time, I lay down on my back and look up at my ceiling (normal square ceiling tiles) and they turned into glowing hexagons of roughly the same size as they were, interlocked, with the borders radiating and pulsing inward while changing colors throughout the rainbow.

I've done it a number of times and never had a bad experience. Also important to note: I've never done any other hallucinogens. No shrooms, acid, LSD, nothing.

I researched salvia ahead of time, figured out the best likely starting dose, mostly kept it close to that, and followed the guidelines given for optimal experience. No loud music, no needlessly-distracting environment, just a quiet area to focus and relax.

Salvia is crazy. The first time I smoked it I saw this dimly lit concrete wall grow leopard print patterns and laughed uncontrollably for four minutes trying to describe it to my friends. The second time I took a bigger hit and everything started to rotate and looked like those photo collages where thousands of tiny images make up one large image (in this case the large image was the real world). Two kids we knew walked by and my buddy told me they were made out of sugar. I wholeheartedly agreed.

On acid and mushrooms you are still very much within your own mind and aware of your own consciousness, but salvia is an insane ego destroying three minute trip through the universe where you may or may not exist. Scary stuff if you ask me.

Man, coke is a weird one. I always thought I had an addictive personality, but I've seen the same as this happen to other people, and coke just.... doesn't really do it for me. I'm constantly shocked by how hard it can sink its claws into people.

So even though I think it's honestly a less exciting party favor than, like, nachos or something, I warn everyone I know against it because you can never tell who will fall headfirst into the abyss.

Many, many years ago when I was a dumb kid, I may have partaken in a drug that will remain unnamed.

An hour into the fairly unpleasant experience, I finally closed my eyes and zoned out. Had what I can only describe as a "vision": out of the randomly swirling fractals stepped a couple old Plains Indian men in full war dress -- feather headdress and all. They looked at me confused for a few moments. Finally, the taller one tentativly asked in a gruff voice "You oatscoop?"

I replied "... yeeeah?" suspiciously.

The looked both disappointed, and the taller one did that awkward side sway/shuffle people do when when they're really uncomfortable, so I started profusely apologizing.

Here I was, some skinny white-as-snow college kid high out of his gourd, sitting in beat up recliner in a shitty apartment surrounded by paraphernalia with Blue Oyster Cult playing in the background, having an honest-to-god vision. I didn't cleanse myself spiritually and physically, deprive myself of sleep/food/water, or have a deep innate respect of ancient traditions. I felt like the world's biggest asshole. Like I was shitting on their culture and beliefs. Hey, sorry everyone that worked hard on their vision quests -- turns out you can just be any loser that smoked something questionable on the weekend.

They did the "it's fine" hand wave, like they recognized it wasn't my fault. It was an accident and I was apologetic, so they relaxed and opened up a bit.

Apparently I was the last male in their family line, and as such they were going to reveal some great knowledge to me, which they told me in a "we're already here, you technically meet the requirements, and we're too old to give a fuck about rituals and cleanliness anyway". They were like the cool grandpa that would offer you a beer as a kid and tell you hilarious stories that you knew better than to repeat to your parents.

So after a bit more apologizing on my part, and more "Jesus kid, calm the fuck down" on theirs, they gave me the knowledge. Your pretty standard "euphoric, dissolve into and understand the entire universe" sort of thing that can only exist in a brain going haywire.

And then for a week I couldn't concentrate and my short-term memory was impaired.

My furniture all talked to me when I did salvia too. It all stood up and started leaving my bedroom, singing "we're going on a journey, we're going on a journey!" But I got really freaked out and yelled at it to stop and ended my trip prematurely. I still wonder about where they were all going...

Holy shit. I am so sorry for your loss. I remember when I was in middle school, I was having a terribly rough time. Dumb as I was I decided to try to end it, using benadryl. I took something like 40-50 25 mg tablets..when I had just gotten to school that day. I remember putting my head down in first period, then when I brought my head back up what I thought was just seconds after, but class had ended. I could barely stand. The fear of dying set in finally, and I knew I had to get to the main office to call my mom to take me to the ER. I managed to get to the office by sliding along the wall. Everyone knew something was wrong. A couple of my friends at the time said they thought they were going to have to pick me up and call 911. They should have, but didnt out of fear. I called my mom, told her I wasn't feeling well, didn't want to worry her until she got to the school. I laid for what felt like an eternity in the nurses office. The walls were changing into demon-like faces that slowly melted down. After what I believe was an hour she finally showed up. Got in the car with her help, and then broke the news that it was an attempt at my life. Broke her heart. Broke mine to see her in so much pain. We got to the ER and they told me that as a 120 lb 15 year old I was very lucky to be alive. I didn't expect what was to follow. Nearly a week of hell because of the side effects. Trust me kids, do not abuse benadryl for fun. You will become desensitized and will want nothing more than to die. Small doses won't hurt, but if you're taking 1000+mg... It leaves you in a week of pure hell.

I remember talking to my dad one night a few years after my uncle died of a heroin overdose when I was young. My dad had some pretty crazy stories from his childhood, and he and my uncle were the closest two in age out of a very large family. My dad always tried to keep his language and stories clean around my siblings and I, but after several stories of the two of them as kids, he just sat back and said, "That bastard killed himself."

My room mates and I went out to the clubs one night and a guy I didn't know well tagged along. We smoked some pot, well a lot of pot, before we rolled into the club. The place was packed elbow to elbow and no tables were free; then we grabbed a free table and ordered beers. The new guy wasn't with us. Minutes drag by and we don't see him; I start to worry and ask where he is; nobody cares. After 30 minutes. I get up and walk around looking for him and find him sitting at the end of the crowded bar, alone. I ask him what he's doing and he looks at me with tears in his eyes and says "I'm dead." "What?" "I'm dead. I've been sitting here for hours and no one will talk to me. I asked the bartender 3 times for a beer and he didn't even look at me. People can't see me. Because I'm dead." "Dude, I can see you, right? We're talking now, yeah? I don't think you're dead. Here, I'll get you a beer, and then we'll go back to the table everyone's at." I yelled at the bartender and paid for a beer, steered my new buddy back to our table, and we all had a good time.

I was addicted to cocaine, crank & crystal meth for 23 years. (ages21-44) My last bender lasted 3 months, July 10,2014-October 1,2014, went M.I.A. from my family wandering around Port Richmond/Kensington Philadelphia. Probably spent 20k in all. At 1 point I was awake for 9 straight days. Pus coming out of left tear duct and these phenomenally insane hallucinations, visual and auditory. The creepiest hallucination sounded like a choir of children maniacally laughing for 3 straight days. Lost 38 lbs. I walked into a place called The Rock which is a ministry for the down and out. Stayed with a guy there for 6 days then went to a rehab for 6 months. A rehab that deals with you on a purely spiritual level. I had been to regular 28 day rehabs 5x over 13 year period and I.O.P. rehab another 5x in between. This last rehab everything clicked and my life has been completely different and my life is changed. Sober for 3 years now and I'm almost 49. Used drugs for almost 30 years overall. I have seen almost every bad thing 1 human can do to another. People murdered (shot,stabbed,beaten), od's, assaults, brain matter, bone, ruptured eyeball, ear torn off, tip of a nose bitten off..just horrendous shit. Life is good now. I am content and happy. An absolute zero desire to ever use drugs again. That feeling has never lasted more than 60 days in the past. Amends have been made and more to be made in the future. Anyway drugs are hell on earth.

Real simple. Not real easy but simple. I finally and truthfully realized and believed I had no control whatsoever anything in my life at this point. I mean nothing. I was absolutely dead inside. The only emotions I felt were rage and fear. I completely gave up trying to figure out how to fix this problem and said to this chaplain who was my counselor whatever I need to do I will do. He asked my thoughts or beliefs as far as God were. From the age of 8 I had been furious, disappointed, disinterested about anything God related. I had been abused while attending a Christian private school(11th grader molested/raped me) this chaplain with zero condemnation felt genuine pity, sorrow and compassion towards me and like a father trying to help his son guided me and picked me up, got me back on my feet. I don't want to get into a long "religious" discussion but the only explanation for me is divine intervention. I feel differently, I think differently and genuinely empathize with others. These feelings were negligible for years. I feel what I believe to be genuine gratitude and grace. My family says this guy isn't the same dad/husband/son we used to know. As far as the abuse, I hadn't told a soul for 33 years. It was not the fault of the school, my parents or God. This guy was just an evil person. Some people just are and for me at this point it doesn't matter why he did it, what his underlying problem was. It just doesn't matter. I told this chaplain the top 3 things that I'd sworn would go to the grave with about 6 weeks after I got to rehab. Dealt with those things and each week since my life has exponentially gotten better. Life is good. Edit: Just woke up and my inbox is filling up. Thank you everyone for the encouragement and positive feedback!😀

Synthetic marijuana, If you even want to call it that. Really it's like a mixture of synthetic meth, crack, angel dust among other things. Many people have had really bad times with it, including myself. Some people have died from it. It's very very bad shit

Which is just as dumb. I understand testing for hard core opiates, morphine and meth that can cause an overall decrease in health but weed? I doubt many employers care about you drinking a fifth a vodka after work, waking up and coming to work with a tiny amount of alcohol in your system. It shouldn't be different for marijuana either.

Its not really like a mixture of meth crack and pcp, it's synthetic cannabinoids which havent been researched in the slightest bit for human consumption. While all the cannabinoids in weed have been used for a very long time from people getting high and medicating and have shown to be pretty damn safe, synthetic cannabinoids act on that same system but are totally different chemicals. If you have synthetic versions of all the cannabinoids in weed and sprayed them onto herbs, you'd have an experience very very similar to weed.

That being said the experience of spice is terrible and not something anyone should ever try, and i'm very pro-drug. Unsafe cannabinoids that we don't really have any idea the shit they can do to you should not be consumed ever. I hate that its called synthetic weed, it only shares the same class of drugs, they arent the same drug at all.

First year of college, it's like 1:30 am, and I'm out getting a drink of water from the water fountain in the hallway. Some dude wanders in from the stairwell and asks me if I have any drugs. I told him no, I don't, but also being an innocent, polite child who has never dealt with being asked for drugs before, I tack on a hesitant "Sorry?" to the end. He says "No, that's good, don't do drugs" and then wanders back into the stairwell.

acetaminophen (the drug that makes tylenol do what it does) is known to often have VERY damaging interactions with alcohol that can cause severe damage to your liver. Even taking it the morning after can land some people in the hospital. the interaction between the drugs is not well understood, and is not consistent really. but there is considerably evidence that it CAN sometimes be lethal.

The ELI5 description I got from a doctor is that acetaminophen is absorbed through your liver, and your liver can only absorb so much at a time. Booze is also absorbed through your liver, and can only absorb so much at a time. Taking both at the same time is way more than your liver can handle and fucks it up.

Basically TL;DR is alcohol and acetaminophen both are filtered through your liver. If you've got a hangover take ibuprofen, better yet take it before bed and chug some water. That's my go to after drinking and I never really have any hangover.

I worked as a food runner in a hospital for a while, a line worker told us at the end of the night, "Tylenol says not to take more than 8 (?) in 24 hours, I have a horrible migraine, I can take 7 now and the last one before bed, right?" I looked at her and straight face said, "Thank fuck we're in a hospital already, that'll kill you slowly and painfully."

I once bought a quarter of mushrooms because I was going to do them with a friend of mine. We would each take an eighth, one half at first, then the other half hours later, as we were known to do. Anyways, I start munching on them and my friend bails last minute. So over the course of probably 10 hours I ate all of it by myself and went on on a Facebook tangent about Mark Zuckerberg being the second coming of Christ. Then I go outside and play in the snow thinking it was raining diamonds, then I go to the bathroom and proceed to walk around in circles losing my mind. Shapes and textures were starting to manifest on the walls and they started spinning, but I was having a great time just geeking the fuck out. Then I found an ingrown hair on my tummy-tum and decided to pop it. Well, this is where the shrooms turned on me. I had gotten it out, but I was convinced there was more. So I kept at it until I saw what looked like a worm come out and start wiggling. Then I felt this really hot flushing feeling come over me and start coursing through my veins. I immediately started to panic. So I ran upstairs to my room and laid on my bed looking for the mellowest music to listen to to maybe calm me down. I chose Coldplay. The red sheets I was laying on started to seem like a blood red sea that I was sinking into and I was getting really hot, so I stripped butt naked and opened the window. This wasn't cooling me down, so I start to actually lean out the window all the while thinking "I'm like one of those fucked up statistics where people take too much psychedelics and jump from windows". The sun was starting to come up and it made the trees look like they were on fire. I kept trying to tell myself that it was a bad trip, shrooms won't kill you, and that I was going to be alright. Not working. So instead I sat in corner and rocked myself to sleep saying "Jesus is love" over and over and over. I don't even believe in God. Then I passed the fuck out and swore off shrooms for years. I've done them a few times since, but now I just nibble. I'm terrified of having an intense trip again. I haven't done them for like 2 years and probably won't do them again. That one bad trip kind of ruined psychedelics for me, which sucks, they're a lot of fun.

Feel that. My last few acid trips were way too intense. Basically blanked out for maybe hours at a time (maybe minutes) with my thoughts working like one of those stroke infomercials where you see the words blur on the screen and the letters get all mixed up, except it was happening in my thoughts. And I couldn't for the life of me remember what was going on with me, I basically spent hours going what is acid am I on acid what is acid and trying to google it on my phone only to not be able to read the articles forgetting about what I was doing and then repeating the same thing. Not bad bad, though the initial realization that oh fuck this is going to be strong did induce some panic, but just weirdly out of control with zero comprehension of what was happening.

I remember 7 tabs of some very nice acid dosed at 150ug each. I actually forgot a lot of things during the trip. Took me like 3 hours before I realized I could go to the bathroom and pee and I wouldn't feel like I had to pee. I was talking and thinking to myself in gibberish for just about the whole time.

Ah yes. The gibberish. I took lsd with my brother and my best friend and his girlfriend one time. About halfway through, I had an out of body experience while talking with my brother and was able to watch the convo from two feet away.

The words made no sense whatsoever. His nor mine.

I simply said, "yeah that's what i know I think but also don't really nice not"

He replied with, "yeah but what if we think maybe"

Clearly I didn't lend to the idea that we wanted any, but we agreed that we needed to get our chew from the car.

I shit you not, the words made no sense, but we were on the same page. It was one of the most amazing things I've ever experienced.

I remember I dipped maybe 5-6 times with some pretty basic chew. I enjoyed the buzz and taste so when my pal who chews gave me some of his harsher stuff I took it. Nearly puked and had to sip on OJ and crackers, stopped dipping when I realized that taste would become normal to me.

You're my soul mate. I've done that many tabs on a multitude of occasions. My favourite part is where you lose your fucking mind and forget how to speak and form words so you try to speak by some fucking weird form of impromptu sign language and grunting. Then the weird epiphanies start coming. Oh shit, I have hands?GUYS, I HAVE FEET TOO. Loved every moment of going full retard on 7 tabs. Wish I wasn't on mobile so I could drop some great stories. Only bad part is the acid shits when you don't know if it's a fart or not. Oh, and the jaw spasms suck when you forget about them when you've got your tongue between your teeth.

Not trying to necessarily change your mind, but I felt, as an anxiety and panic attack sufferer myself, I'd give you my experience.

They were simply amazing. Nothing like weed. Totally different trip, totally different high. Really eye opening, mind boggling experience. But that wasn't the best part for me.

The best part for me was that for two full weeks after taking them, my anxiety was the lowest it had been for a decade. I actually knew what it felt like to feel happiness and contentment, for once. It was beautiful, and life changing. I still struggle with anxiety, but knowing that I even have the capacity to feel how I did those two weeks after trying shrooms... It helps so very much.

Now, don't just go out and take them because I said all this - YMMV and they affect everyone differently, but it truly changed my life.

SAME! thought I was going to hate the trip / comedown when in reality I never felt more at peace in my life the night I did it and the following few weeks after. I know they are starting trials for using them as antidepressants / anti anxiety meds but I doubt it gets far legally. I try to explain this to people who haven't ever tried shrooms (from conservative Midwest) and nobody can understand the feeling unless you've done it and felt the calmness.

Adding on to this. Shrooms changed my brain chemistry for the better. I wasn't diagnosed with depression but I had a lot of internal struggles pre-shrooms. My first trip included many epiphanies and just being one with the universe. Post-shroom I am more content and everyone who meets me explains me as "chill" which is s newer phenomena. I don't feel as bothered by things. I try to tell my friends (who don't do drugs) my experience and they roll their eyes. I still can't smoke weed due to the paranoia it gives me. Also I'm an advocate of safe and moderate MDMA use! I hate to say it but drugs might have made me a better person!

Had a few friends trip on acid one night when someone's parents were gone. This guy's stove elements are always red, which is a silly design choice, but an important one. Buddy wanted to scare another guy so he slammed his hand down on one of the other burners as they were making perogies, making him think he burnt his hand. Suddenly, the guy goes blank and goes into a full on bad trip, he was convinced everyone else were cops trying to catch him for killing all of his friends in a perogie fire. Ran out of the house banging on neighbors garage doors yelling for help. Luckily nobody saw him and one of the other guys was able to get him back inside and calm him down, but this occurrence has convinced me I'm probably fine without doing acid.

Pretty much how my worst trip went down. Convinced myself I had murdered my best friend and raped his wife despite them both sitting in the room talking to me. We had finished a pretty dark movie just before dropping acid and I think it was still pretty fresh in my mind as I came up and peaked.

A friend of mine went to a music festival with a different group of friends. One of those guys did DMT and passed out for about 7 minutes. He woke up freaking out because apparently while he was out, he lived an entire lifetime as a mayan boy/man.... lemme repeat myself.. he lived and ENTIRE lifetime as another human being from another time and place. He described waking up, going about his day everyday. He slowly grew up, found a wife, had kids... all that. Then we just woke up. He was kinda depressed for a few weeks apparently. stuff is just nuts

There's a thread on Reddit about a guy who got knocked out (hit by car? Can't remember) but he said while he was out he lived an entire life with a girl, kid, house, etc. When he came back he got super depressed because he missed them so much, even though they never existed to begin with.

I've experimented with Wim Hoff's breathing technique(look this up), and he claims that it releases DMT in your brain when you do it. I haven't had any experiences where I think that's happened yet though.

Took a tab of acid on a family vacation. We were at the beach for a week in florida but each year we go to Ichetucknee springs to go tubing. Its a beautiful place with crystal clear water and you tube down a stream for 2-3 hours. Anyways I dropped my acid 30 minutes before we got there and by the time we got there I was on the come up. I spent the first hour and a half snorkeling by myself and having a blast. Around an hour and 45 minutes in my mom made me tie off to my grandmother because she kept falling behind. Fuck. So I was stuck with my old grandmother while tripping dicks. I was able to keep my composure for the most part but right before we got to the end of the stream. I was still tripping pretty hard. (im terrified of snakes) My grandmother screams out of no where and says SNAAAAAKKKE. My reactions were late but I turned around and there it was. A black water snake (probable water moccasin) swimming towards me and granny. I almost fained, no lie, but instead I bailed on the tube and started swimming up stream. I probably looked like a mad man. Apparently it swam up to my grandma and went right by her to get to the other side. The adversity in my situation came when my grandma finally got to the landing point that I had already swam to and she was very angry, and I wasnt responding to her angry very well since I was rolling on acid and im sure i just looked confused and misplaced. She thought I was just drunk because I had been drinking at the beginning of the stream. Anyways, nothing that bad came out of it, but. DONT DO ACID NEAR GRANNY

Edit: Thanks for supporting me and giving me upvotes even though I left my granny behind!!!

Edit: I also just realized that I have 30 typos in my story. Sorry for not paying closer attention.

LMAO I took a tab of acid on a train from DC to Pittsburgh as I was headed back to school. At the time it seemed like a great idea, but it turned out to be really stupid. I get REALLY energetic when I drop acid and need to move around, and of course you get super sweaty and dehydrated. Other than watching everything move by me in slow mo it was a pretty miserable 3 hours. I felt bad for the person sat beside me because I couldn't stop getting up out of my seat to move around, and since I have green eyes my massive pupils were SUPER obvious.

A few months later I dropped acid on a plane...also not one of my brighter decisions.

My mom did that after she was arrested by the FBI, after she stole a Ford Pinto and robbed a liquor store, then fled to New Mexico; at 14. If I remember correctly the only reason the FBI got involved was because she was considered a endangered runaway? Any way she was holding up at a motel selling LSD, she said the second she heard a car tearing into the parking lot she knew it was them. So she immediately took her stash, some god awful amount. Well the plan was to transfer her via helicopter to Phoenix, then fly her back with some other detainees, that didn't happen. She said about 3 minutes into the chopper ride she's flipping out, she said the agents looked like Medusa having snakes grow out of their face. Now of course they didn't secure a 14 year old girl to the seat, so she proceeds to get up and try to open the door, during the scuffle she tries to choke an agent with the handcuff chain. This is where it got blurry, they immediately landed, and I believe they had Ambulance pick her up. She got sent to the hospital just to get tranquilized, then drove back in a van. She was sent to a prison for juvenile offenders in Chowchilla, California, where she met my dad. Back in the 1970s the boys and girls rec yard was only separated by a chain link fence, so they could converse. Probably not the best idea.

Watching that movie as an adult felt like a bad acid trip; it was messed up (especially the Flooglies) and I did not at all feel the same "coolness" as when I watched it as a kid. Would acid have made it better or worse--who knows...

I'm the other way around. I was too old for it when it came out, but now I see it through my kid's eyes. Plus, I love how all three of them were made in the same office building where they do the post production. It's like a home movie.

It took me a moment to realize you were talking about the movies and not acid and your kids. Thinking that all three of your kids were made in the same office, and that somehow had something to do with acid had me very intrigued to keep reading. Then I realized you meant the movies. And no, I'm not high right now lol.

I wish that was the reason, it was over a Vicodin and Valium bender. I definitely developed a drug problem because of her, but after she died I had to let go of any resentment. I tell myself she wasn't the best mom, but she was still my mom, and all I had.

Id be glad to explain party monster. I had planned the moment out for a very long time and my cousin was supposed to be with me but he ended up being sick the day we went. At first I was like hell Na I'm not gonna do it by myself, but half way there I was just like fuck it lets go. Honestly take the snake out of the equation and I would have been perfectly fine.

Once saw a patient that took something they did not know what it was. It triggered a manic episode and they could not say who they were, what time of day it was, where they were, etc.

Another still had acid in their system and was tripping hard. He thought he was part of Seal Team Six and was trying to fight ISIS. He then couldn't go to sleep because he thought they were going to get him. He then proceeded to hump the floor because it was deter the people that were trying to get him.

When I was in my junior year of high school, I went to this girls house with her and a couple of her friends to hang out. I had smoked weed before but hadn't smoked in 2 years or so. The girls brought out some weed and being the only guy there, I decided I had to show them I wasn't soft and started smoking. I had no tolerance at the time so I was pretty damn stoned after only a few hits. I went inside to go get some water and on my way out to the patio, I ran into the sliding glass door. I was so stoned that I didn't realize the door was shut and I ended up breaking my glasses in the process. So much for trying to impress the ladies :/

My buddies and I all dropped acid and decided to walk to Best Buy since it's literally 1000 feet from my house. We thought looking at the 4k TV's while tripping would be a fun time. We get to Best Buy, tripping our balls off and start wandering around the store. We were making our way to the TV's when a random employee came up to us and started giving us this speech about store credit cards, how they had layaway plans, how there were experts in each department to help us etc. We were all terrified and tripping sack but stood there and listened to him quietly until we just said "Cool. We'll come to you if we have any questions" and he walked away. We looked at the TVs for a bit but were so freaked out by the employee from earlier that we decided to just leave. As we were making our way out, another random dude from comcast stopped us and started asking us about who we get our cable from, what our internet speeds were etc. It went something like this:

Him: "So what are your current internet download speeds

Me: Umm, yes.

I guess one of my friends was still shaken about the other employee and this guy set him off the edge so he just shouted "FUCK THE INTERNET" and sprinted out the door. My other friend and I just kind of looked at the door, looked back at the salesman, looked back at the door, looked back at each other and bolted out the door. Don't go to Best Buy when on acid kids.

I have a bunch of "never do drugs" stories but these are the two that are the most relevant

First time I tripped on acid we decided to walk to the corner store at like 3am for snacks. Everything was fine, I was still fried out of my mind but was able to pick out what I wanted. I was taking a little longer than my friends because they were in a rush to get out of there and I recognized that what they grabbed wasn't enough food. So as I'm making my way to the drinks to pick up one last thing a whole mob of drunk 30-somethings walks in and starts trying to talk to me. I'm this tiny little 20 year old minding my own business, trying to keep my eyes from focusing on every texturing I can see shifting and changing color. They're like "where's the party, you got all the munchies" I kinda brush it off and then two women who looked not only too old for me, but super sluttily dressed and covered in makeup, walk up and start trying to talk to me. I can barely remember what they said but one put their arm around me. At this point I'm handing my items to the cashier. I literally take her arm off me, turn around to all these fuckers trying to chat up this guy who is clearly uncomfortable (me) and proclaimed "I'M TOO HIGH FOR THIS SHIT LEAVE ME ALONE GODDAMNIT!" at which point they decided to leave me alone. It was fucking wild. Meanwhile my friends are outside laughing and feeling sorry for me. It was such a surreal situation. Left me with a good story though.

Oh jeez that sounds awful. I can barely contain myself when one or two strangers are just in my general vicinity when I'm tripping. I'd be mortified if a whole group of them approached me and started trying to talk to me

Last time I was in Best Buy, like 2 yrs ago, a Comcast rep approached me. She was about my age, maybe a couple years younger and very shy, and probably just started. So I let her open up just to give her some experience, I'm in sales, it's tough, I know the feeling of breaking the ice and understand what she was going through. To get to that point was a huge win when most people just look the other way or do the awkward hand wave and walk past you.

Anyway, next thing you know her boss comes flying over, probably my age, and just goes for the jugular. Asking me about all kinds of things. What killed me though is when he asked about my credit, to which I replied, aside from it being none of his business, it's excellent. Apparently a 20-something dressed in beat up clothes can't have an excellent score? He kept saying cmon man what is it really? Im trying to help you we have credit lines, etc... I'm just like, "???? Fuck off kiddo. She was doing 10x better without you around." And to her, "Goodluck in the future, sales could be good for you but not with this guy as your boss."

That experience was pretty much it for me. Amazon and Newegg sale the same products and are frequently way more affordable.

I was busing home from college waiting for my connecting bus when decided to smoke up. The moment I got on the bus I felt like I was in a tony hawk game trying to balance the bus as my own skatebaord. Stupid part is there were plenty of seats but I still stood there like a moron in the middle of the bus with my arms out. No one seemed to notice or care.

Got home and was super dizzy from this stupid idea and spent the next 4-6 hours throwing up non stop on a mostly empty stomach.

So i had a similar event with different results. I guess this guy had quite the coke bender, multiple days of nonstop partying and no sleep. He eventually passes out against a wall in sort of a squatting position, for 18ish hours. This cut off blood supply, and caused clots to form. When blood finally did reenter his legs it caused/contributed to compartment syndrome: a condition where your veins are blocked off for one reason or another (theres a few options) but blood keeps going into the system adding to swelling and exasperating the blockage and damaging other tissues.

Anyways we did multiple massive fasciotomies to alleviate the pressure. One on each side both above and below the knee on both legs. It was pretty gnarly.

A correctly folded protein is in the "Native State". When a protein is denatured, hydrogen bonds holding the protein in that specific shape are broken and will likely reform later but to the wrong Amino acid in the sequence. This creates a completely different shape even though the protein is made of the exact same Amino acids. Protein binding sites are extremely specific and will not bind to a protein that will not fit the site.

Imagine a horseshoe. It is a very rigid U-shape. Now the horseshoe somehow melts in to an S-shape. It is still made of the exact same elements but when thrown at the Post will not perform its proper job at all.

Proteins denature or misfold on their own in your body all the time. There is a process for attempted refolding, some can on their own with time (several hours), others use a Chaperone protein. If refolding to the Native State fails after multiple attempts, the misfolded protein is marked for destruction by another protein and destroyed by yet another.

Now imagine your entire body is cooking your proteins and denaturing them. Huge numbers of proteins are being denatured and marked for destruction. Proteins can act as: enzymes, regulatory molecules, signaling molecules, docking + carrier molecules, structural molecules, and more. Large amounts of cells will have these normal functions interrupted and such a large scale denaturation would likely cause organ damage as well.

Proteins are three dimensional structures made up of chains of amino acids. A protein's 3D structure essentially determines it's function. When a protein is denatured, the bonds between the amino acid chain that give the protein it's 3D shape are degraded rendering the protein unable to carry out its function. For example, it you heat denatured hemoglobin (the protein found in red blood cells responsible for binding to oxygen) they would not be able to bind to and deliver oxygen to your cells.

It usually means they go into cardiac arrest, aka their heart stops. IIRC technically cardiac arrest is code blue but it's the most common code so they just say coding (or crashing) So yes unfortunately it means he's dead.