Some psychosocial developments in the context of HIV/Aids are key elements for designing projects focused on overcoming difficulties generated by the rationality of specialized approaches. This study aimed to identify some emerging elements of the therapeutic relation in the process of caring for people with Aids in order to support the development of professional training programs. Semi-structured interviews with ten professionals in a teaching hospital in the interior of São Paulo permitted the establishment of six thematic categories related to the context of HIV/Aids care: delivered treatment, established relationship, limits of care, teleological approaches, work ownership and counterpoint to experience of practice. These results reveal that caring for people with HIV/Aids requires other elements in addition to specialized technical knowledge, which in turn generates symmetry in the establishment of bonds between professional-patient, allowing to construct together with the professional teams work.