Welcome to the Journal

Journal of Medicinal and Organic chemistry has turned out as one of the most important interdisciplinary area of science over the years and catering the ever growing need for new medicine and compounds. Combating with numerous diseases was not possible without constant support from medicinal and organic chemistry since ancient times. Modern high throughput technologies enabled us to explore and generate ample number of compounds and test their efficacy in relation to different disease conditions.

The fast growing subject demands a global platform for discussion of various important aspects of the subject. Research and Reviews: Journal of Medicinal and Organic Chemistry provide common podium to the academicians, researchers and student community to enhance, share and update their understanding in the associated subject of medicinal and organic chemistry.

Research and Reviews: Journal of Medicinal and Organic Chemistry is a peer reviewed open access journal which accepts contribution in the form of a research, review and short communication article.

This quarterly periodical encompasses the following topics under its broad scope and also allows submission in the allied subjects.

We are delighted to invite the global scientific community to contribute and share their knowledge through this open platform.

Natural Products Chemistry

Natural product is a chemical compound produced by a living organism which is found in nature. Natural products can also synthesize by chemical synthesis and plays an important role in the development of the organic chemistry. In the case of organic chemistry natural products is usually restricted to purified organic compounds

Bioactive Heterocyclic

Heterocyclic, their preparation, transformation, and properties, are undoubtedly a cornerstone of organic chemistry. Several heterocyclic possess excellent biological activity almost without bearing any substituents, which means that their heterocyclic core is definitely part of the pharmacophore. Examples of such scarcely substituted and highly active heterocyclic are the two bipyridyl derivatives such as amrinone which is used in the treatment of congestive heart failure

Heterocyclic Compounds

Hetero cyclic compound is a ring structure that has at least two different elements as its members of ring. It is the branch of chemistry that deals with the synthesis properties and applications of heterocyclic compounds classified as heterocyclic probably constitute the largest and most varied family of organic compounds. After all, every carbocyclic compound, regardless of structure and functionality, may in principle be converted into a collection of heterocyclic analogs by replacing one or more of the ring carbon atoms with a different element.

Pyrimidine

Pyrimidine is an aromatic heterocyclic compound it has nitrogen atom at 1st and 3rd positions. The pyrimidine derivatives include nucleotide thiamine and alloxan. Pyrimidine derivatives such as uric acid and alloxan were known in the early 19th century. Any of several organic compounds derived from or structurally related to pyrimidine is nitrogen bases uracil cytosine and thymine.

Epigenetic Drug Discovery

Epigenetic drug discovery is one of the fastest growing and potentially groundbreaking target spaces for developers. Over the past few years, a significant increase in small molecule inhibitors chemically modulating enzymatic activity of Histone Methyltransferases Histone Demethylases and disrupting interactions of the BET family bromodomains have rapidly translated into clinical investigation. Epigenetic drug discovery shows great promise for new drugs

Related Journals of Epigenetic Drug Discovery:

Drug Design, Development and Therapy, Drug Discovery Today: Therapeutic Strategies, Drug Development Research, Letters in Drug Design and Discovery, American Journal of Drug Discovery and Development, Drug Discovery World

Chemical Neurobiology

Methods and Protocols assists with the design, characterization and validation of new chemical tools for neurobiology by providing detailed protocols of procedures and assays deemed essential for the successful development and implementation of such tools. Divided into three sections, topics cover chemical probes of membrane protein structure and function, photochemical control of protein and cellular function, and chemical probes for imaging in the nervous system

Agro Chemistry

Agro chemistry is also known an agricultural chemistry that it is a research and development branch of chemistry and the branch of production of agriculture. These studies denote the relationship between plants animals’ bacteria and their environment. It involves the production protection and use of crops. The main goal of agro chemistry is to expand understanding of the causes and effects of biochemical reactions.

Small Molecule Libraries

A small molecule is a low molecular weight organic compound. Most drugs are small organic molecules. The upper molecular weight for a small molecule is approximately 900 Daltons. Small molecules, often with molecular weights of 500 or below, have proven to be extremely important to researchers to explore function at the molecular, cellular, and in vivo level. Such molecules have also been proven to be valuable for treating diseases, and most medicines marketed today are from this class. A key challenge is to identify small molecules effective at modulating a given biological process or disease state.

Chemistry Biology

It involves the fields of chemistry and biology that is the application of chemical techniques tools and analyses to the study and manipulation of biology. Chemical biologists attempt to use chemical principles to investigate the biology or to create new function. Advanced biological chemistry interests include diverse topics such as nucleic acids DNA repair conjugate chemistry represents the union of chemistry

Medicinal and Organic Chemistry

Medicinal chemistry deals with analysis of the chemical compounds in the form of organic molecules. Compounds commonly used in medicinal chemistry are mostly organic molecules. Medicinal chemistry mainly focuses on the small organic molecules and natural products. The main theme of medicinal chemistry is to identify the novel active chemical compounds and it provides suitable SAR and chemical characteristics associated with the active medicament.

Chemical Proteomics

Chemical proteomics is emerging as a powerful pre-clinical component for the identification and validation of novel drug targets. A substantial challenge in probing biological systems remains the identification of targets being perturbed and causing favorable phenotypic response. Critical to the success of discovery programs is the challenging aspect of DE convoluting targets and pathways elucidating the mechanism of action of chemical compounds. Advances in chemical proteomics and quantitative mass spectrometry, introducing high-throughput workflows for target DE convolution, disease pathway analysis and understanding cellular protein dynamics, have recently improved pre-clinical target validation.

Marine Chemistry

Marine chemistry is also known as ocean chemistry which is initiated by turbidity currents sediments PH levels and atmospheric constituents and it manly focus on the chemical study of the ocean environments. Increased carbon dioxide levels resulting from anthropogenic factors have a potential impact on the marine chemistry

Novel Drug Discovery

The pharmaceutical sector, a cornerstone of the healthcare industry, is undergoing dramatic change, primarily caused by reduced output of new medicines from research and development (R&D) laboratories, drug pricing pressures, stricter regulatory environments and the overall current economic downturn. This makes demands of all pharmaceutical companies to find better ways to increase their output of new drugs, through innovation, to both treat patients and meet their shareholders’ expectations.

Related Journals of Novel Drug Discovery:

Modern Drug Discovery, Drug Discovery Today: Technologies, International Journal of Drug Discovery, Current Opinion in Drug Discovery & Development

Industrial Medicinal Chemistry

Industrial chemistry helps you understand what you are doing before you do a practical in the lab here you have to really understand what you are doing and why you are doing it. medicinal chemistry focusing on finding new medicines to treatment asthma which will allow you to perform an important role in the drug discovery industry as well as a firm grounding in general chemistry, research methods and relevant laboratory techniques.

Medicinal Preparations of Proteins

These are common types of proteins along with globular proteins. They are divided as membrane proteins transport proteins .Membrane proteins are the signals between cells and external environment. Transport proteins move the molecules and ions across the membrane. Integral membrane proteins permanently attached to the membrane

Organic Synthetic Chemistry

Organic synthesis is the study of how we build molecules ranging from complex, biologically active natural products to new materials. Because synthesis allows a chemist to construct entirely new structures. It also involving the scientific study of the structure properties and reactions of organic compounds and material. The range of chemical studies in organic chemistry include hydrocarbons.

Drug Discovery and Optimization

Many of the technologies for lead discovery overlap with lead optimization as researchers attempt to incorporate the best drug characteristics early in the process. In the field of medicinal chemistry biotechnology and medicine drug discovery is the process by which new candidate medications are discovered. Modern drug discovery involve the identification of screening hits.

Computer Aided Drug Design

Computer aided drug design is also known as rational drug design it is the process of inventing new medications. Generally the drug will be a organic molecule that may activate or suppress the function of proteins. The type of modeling is often referred to as computer aided drug design. The basic goal in drug design is to predict whether a given molecule will bind to target or not.

*2016 Journal Impact Factor was established by dividing the number of articles published in 2014 and 2015 with the number of times they are cited in 2016 based on Google search and the Scholar Citation Index database. If 'X' is the total number of articles published in 2014 and 2015, and 'Y' is the number of times these articles were cited in indexed journals during 2016 then, impact factor = Y/X