ChemBioDraw by CambridgeSoft: Paid((iOS, Windows) free 2 week trial; purchase price: $1500-$4000; universities often have free academic access, iPad App version is $9.99 but is only for drawing. It is not the full publishing suite.)

Synthesis Databases:

Chemistry By Design by Prof. Njardarson at the University of Arizona. “An interactive virtual flashcard that would allow students to test their skills using known synthetic sequences [to build complex molecules].” This is an ambitious and growing body of work aligned with the idea of advancing organic synthetic knowledge by case study of structurally complex targets (not for the beginner), an interesting approach to the study of the art and science of chemical synthesis. Available free on iTunes and Android App stores.