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Conventional Methods for Diagnosis
of Ehrlichiosis and Anaplasmosis

July 2010

Overall, the performance of Ehrlichia and Anaplasma serology by IFA is good, with sensitivities typically ranging between 80 and 90% for IgG-class antibodies, while lower sensitivities are observed for IgM. In addition, the specificity of the IgG test is reported to range between 80 and 100%, while there is lower specificity for IgM due to cross-reactivity with other infectious and non-infectious etiologies.