Delta 1 - important questions

Q1: What is the magnitude of benefit of any antibiotic therapy over placebo?

Appears as large as 60%-80% mortality benefit but magnitude of benefit on clinical parameters not as clear
Q2: Is the benefit of antimicrobial therapy in current trials measured in the same way as in the original trials showing benefit?
Yes and No
Q3: Is the magnitude of benefit of therapy over placebo large enough that it should not affect the selection of the overall delta for a trial?
Yes