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Pursuant to section 10(a) of the Federal Advisory Committee Act, as amended (5 U.S.C. Appendix 2, notice is hereby giving of a meeting of the Secretary's Advisory Committee on Xenotransplantation.

The meeting will be open to the public; however, seating is limited and pre-registration is encouraged. To pre-register, please contact Capital Consulting Corporation (Joanne Mowczko) at 301-468-6001, ext. 418. Individuals who plan to attend and need special assistance, such as sign language interpretation or reasonable accommodations, should notify Ms. Mowczko is advance of the meeting.

Name of Committee: Secretary's Advisory Committee on Xenotransplantation.

Date: March 11-12, 2002.

Time: March 11—8:00 am to 5:00 PM. March 12—8:00 am to adjournment.

Agenda: The SACX will focus on a variety of issues relating to the science of xenotransplantation and to informed consent issues in xenotransplantation clinical trials. The first day of the SACX meeting will include presentations and discussions of endothelial cell-host interactions in solid organ xenotransplantation; transgenic and cloning technologies; cellular transplants; extracorporeal technologies; complement and coagulation systems; and immune rejection and tolerance. The second day will include concurrent breakout sessions during which the SACX Working Groups will convene, and plenary discussion of their progress. Closer to the meeting, a more updated agenda will be available electronically at http://www4.od.nih.gov/​oba/​Sacx.htm

Public Comment: Individuals who wish to provide public comment (oral or written) should contact the SACX Executive Director, Mary Groesch, by telephone at 301-496-0785, or email at groeschm@od.nih.gov.