Authors:

Selwa Boularaoui(KUSTAR - Khalifa University)

K. Evans-Lutterodt(BNL-NSLS)

S. Lee(KUSTAR - Khalifa University)

A.F. Isakovic(KUSTAR - Khalifa University)

The need to understand protein structure and perform treatment lead to the
use of X-ray and particle-based radiation. Since the use of such radiation
has undesirable side effects, mostly through the damage to proteins, it is
important to continuously work on decreasing radiation damage. We outline
the proposal to use the kinoform refractive optics to focus X-rays on the
nanoscale to minimize the radiation damage to protein crystals under study.
These optics devices are nanofabricated from low-Z elements (silicon,
diamond) and can be used at synchrotron X-ray radiation facilities. We
discuss the automated setup that performs nanopositioning of the
nanofocusing element, and collects the chemical and structural protein
solution under study. We offer simple mathematical models in irradiation and
in treatment that help optimize the radiation parameters.

*This work is supported in part by Khalifa University IRF-Level 1 Fund. The work at BNL-NSLS is supported through US DOE, Office of Basic Energy Sciences.

To cite this abstract, use the following reference: http://meetings.aps.org/link/BAPS.2013.MAR.F46.5