Tag Archives: POEMS

The debate on twitter illustrates the multiple differentials that exist in this situation. Most people pointed out that amyloidosis could cause the symptoms and signs described in the case (hepatomegaly due to infiltration, cardiomyopathy causing peripheral oedema, nephrotic syndrome causing … Continue reading →

The patient is counselled regarding the presence of a paraprotein and kept under regular follow up. After 3 years his paraprotein has risen only slightly to 14g and he is briefly lost to follow up due to personal problems. When … Continue reading →

The patient is generally fit and well, with no bone pain, B symptoms or neuropathic symptoms. He has had diarrhoea intermittently for a number of years, interspersed with bloating and constipation. The gastroenterologists felt the history was of classical Irritable … Continue reading →

A 45 year old man is referred to Haematology clinic. He has had a battery of blood tests requested by the gastroenterologists who were investigating him for diarrhoea. These investigations revealed little except for the presence of an IgG paraprotein … Continue reading →