Percy Julian, Robert Robinson, and the Identity of EseretholeAddison AultThe Nova production Percy JulianForgotten Genius, which included the very public disagreement over the identity of "eserethole," the key intermediate for the synthesis of the alkaloid physostigmine, left three important chemical questions unanswered.Ault, Addison. J. Chem. Educ.2008, 85, 1524.

Constitutional Isomers |

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Natural Products |

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Synthesis

A Green, Guided-Inquiry Based Electrophilic Aromatic Substitution for the Organic Chemistry LaboratoryEric Eby and S. Todd DealThis alternative, electrophilic aromatic substitutionan iodination reaction of salicylamide, a popular analgesicuses environmentally friendly reagents and serves as a guided-inquiry experiment in which students are asked to predict the orientation of the substitution reaction and determine the product's structure using FT-IR spectroscopy.Eby, Eric; Deal, S. Todd. J. Chem. Educ.2008, 85, 1426.