Shenandoah University left the USA South on July 1, 2012, to become a full member of the
Old Dominion Athletic Conference, a league in which it held associate membership in several sports.

Christopher Newport University left the USA South after the 2012-2013 season to join the
Capital Athletic Conference in all sports except for football which will remain a USA South affiliate member through the 2015 season.

On May 10, 2012,
Covenant College and
Huntingdon College announced plans to leave the Great South and join USA South Athletic Conference beginning in the 2013-2014 season.

† - Women's college, therefore not competing in men's sports.
‡ - William Peace, formerly known as Peace College, began admitting men for the Fall 2012 semester and is currently sponsoring men's sports.
^ - Football-playing member