The MESA 4I65 is a general purpose programmable I/O card for the PC/104-PLUS bus. The 4I65 uses a 200K gate Xilinx FPGA for all logic, so it is truly an Anything I/O card. The FPGA is downloadable from the PC/104-PLUS bus side, allowing creation of almost any kind of specialized I/O function, even including micro-controllers in the FPGA. Several pre-made functions are provided, including a 12 channel host based servo motor controller, a 4 or 8 channel micro-controller based servo motor controller (SoftDMC), and a 8 channel, 32 bit timer counter card capable of running at 100 MHz. VHDL source is provided for all examples. All I/O bits are 5V tolerant and can sink 24 mA. Pullup resistors are provided for all pins so that they may be connected directly to opto-isolators, contacts etc. The 4I65 has 72 I/O bits available on three 50 pin connectors, all connectors use I/O module rack compatible pinouts. Several I/O interface daughter cards are available for the 4I65. These cards include a 4 axis 3A Hbridge, a 2 Axis 3A stepper motor driver, an analog servo amp. interface, an RS-422/485 interface, and a debug LED card.