..In conclusion, retention of object-location learning in the elderly may be modulated by noninvasive brain stimulation, a finding of potential relevance not only for normal aging but also for memory deficits in pathological aging...

..G-CSF has been shown in animal models of stroke to promote functional and structural regeneration of the central nervous system. It thus might present a therapy to promote recovery in the chronic stage after stroke...

Transcranial direct current stimulation over multiple days improves learning and maintenance of a novel vocabulary

..Studies assessing the impact of multiple stimulation sessions on learning that may induce long-lasting behavioural and neural changes are scarce and have not yet been accomplished in the language domain in healthy individuals...

..In the present study, we show with functional magnetic resonance imaging (fMRI), that different brain regions may be involved in immediate versus long-term success of intensive language training in chronic post-stroke aphasia patients...

Integrity of the hippocampus and surrounding white matter is correlated with language training success in aphasia

..Moreover, they show that genotype-related differences in neurophysiology translate into behavioral differences. These findings might contribute to a better understanding of the mechanisms of interindividual differences in cognition...

..These findings suggest that hemispheric specializations for language and spatial functions interfere to some extent and favour additional recruitment of the opposite hemispheres for spatial functions...

..It therefore appears as an attractive and feasible drug candidate for the treatment of amyotrophic lateral sclerosis (ALS). The current pilot study was performed to determine whether treatment with G-CSF in ALS patients is feasible...

A shift of paradigm: from noradrenergic to dopaminergic modulation of learning?

..Both d-amphetamine and levodopa are thus potent drugs in enhancing learning in humans. We here discuss why the efficiency of both d-amphetamine and levodopa may be related to dopaminergic rather than noradrenergic actions...

Lucia KertiFrom the Departments of Neurology L K, A V W, A W, A F and Biostatistics and Clinical Epidemiology U G, NeuroCure Cluster of Excellence A V W, A F, and Center for Stroke Research Berlin U G, A F, Charite University Medicine, Berlin and Department of Psychiatry D R, University of Halle, GermanyNeurology 81:1746-52. 2013

..Subsequently, we expand on possibilities of adjuvant therapy in human rehabilitation using cortical stimulation and pharmacological treatments. Finally, we suggest future directions for research in this field...

Determining the hemispheric dominance of spatial attention: a comparison between fTCD and fMRI

..Therefore, scanning large cohorts with fTCD for hemispheric dominance during Landmark task will provide results consistent with fMRI. FMRI can then be used for in depth assessment of the specific patterns of activation...

Gianpiero LiuzziDepartment of Neurology, University of Munster, GermanyNeuropsychologia 46:2824-30. 2008

..In the frame of the motor theory of speech this finding suggests that the system of gestural communication, from which speech may have evolved, is not confined to the hand but includes gestural movements of other body parts as well...

Magnetoencephalographic evidence for the modulation of cortical swallowing processing by transcranial direct current stimulation

..These neuroplastic effects were associated with subtle behavioral gains during complex swallow tasks in healthy individuals suggesting that tDCS deserves further evaluation as a treatment tool for dysphagia...

The influence of spatial registration on detection of cerebral asymmetries using voxel-based statistics of fractional anisotropy images and TBSS

Siawoosh MohammadiDepartment of Neurology, University of Munster, Munster, GermanyPLoS ONE 7:e36851. 2012

..Finally, we demonstrated that the "multi-contrast individual-hemisphere" approach showed the least residual spatial misregistrations and thus might be most appropriate for cerebral FA-VBS analyses...

White matter integrity in the vicinity of Broca's area predicts grammar learning success

..The aim of the present study was to determine the different patterns of cortical swallowing processing in patients with hemispheric and brainstem stroke with and without dysphagia in the early subacute phase...

..Future studies should try to disentangle the complex effects of COMT Val158Met on brain functions by taking gender, age, ethnicity, endophenotypes, as well as gene-environment and gene-gene interactions into account...

Cortical reorganization due to impaired cerebral autoregulation in individuals with occlusive processes of the internal carotid artery