Investigator HDplex Kit

For multiplex amplification of 12 non-standard STR loci to give additional discriminatory power

Unique kit with non-standard autosomal STRs

12 polymorphic STR markers distributed over 11 autosomes

High discriminatory power for kinship analysis

Reliable differentiation of forensic samples from related individuals

The Investigator HDplex Kit amplifies a set of STR markers, most of which are not featured in commonly used marker standards. This enables the reliable differentiation of forensic samples derived from related individuals and gives heightened discriminatory power in these demanding cases. The genetic analysis is calibrated with BT5 Matrix, an optimized dye technology.

The Investigator HDplex Kit is intended for molecular biology applications in forensic, human identity, and paternity testing. This product is not intended for diagnosis, prevention, or treatment of a disease.

The Investigator HDplex Kit enables the simultaneous amplification of 13 STR markers (D2S1360, D3S1744, D4S2366, D5S2500, D6S474, D7S1517, D8S1132, D10S2325, D12S391, D18S51, D21S2055, SE33, and the gender-specific Amelogenin). These markers include some highly polymorphic STR markers that are not included in commonly used standards enabling higher discrimination in difficult cases.

Procedure

The twelve polymorphic STR markers and Amelogenin are simultaneously amplified and labeled with the dyes listed in the table "Investigator HDplex Kit dyes and corresponding markers".

The amplified loci undergo capillary electrophoresis. The results can be analyzed using dedicated software, such as QIAGEN's Investigator IDproof or IDproof Mixture Software. See the table "Technical specifications" for more information.

For further information on which version of the v9 template files is suitable for your needs, please refer to the Template File Info Note that can also be found in the ''Template File'' section of the product resources.

For further information on which version of the v9 template files is suitable for your needs, please refer to the Template File Info Note that can also be found in the ''Template File'' section of the product resources.