Which factors have contributed to improved postoperative survival following liver transplantation for cirrhosis?

Answer

Advances in surgical technique, organ preservation, and immunosuppression have resulted in dramatic improvements in postoperative survival. In the early 1980s, the percentage of patients surviving 1 year and 5 years after liver transplant were only 70% and 15%, respectively. Now, patients can anticipate a 1-year survival rate of 85-90% and a 5-year survival rate of higher than 70%. Quality of life after liver transplant is good or excellent in most cases.

[Guideline] European Association for the Study of the Liver. EASL clinical practice guidelines for the management of patients with decompensated cirrhosis. J Hepatol. 2018 Aug. 69 (2):406-60. [Medline].

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