The millions of travel earls beginning to migrate across this country for the holidays tonight. Just as a giant storm is taking over the country. The highways are slick, the airports are threatening flights, threatening to send off that domino effect in airports across the country. Abc abc's meteorologist ginger zee is in the storm tonight. Reporter: This may be a preview of your holiday travel -- frustration. That's because in denver, the wild winds are sending snow sideways tonight. In texas, the storms kicked up enormous dust storms that caused 16 accidents and shut down one highway. It's all part of a monster winter storm, hitting right as holiday travelers are starting to move. At the denver international airport late today, plows on the runways, but they weren't able to keep up. Lining building as dozens of flights were canceled. I'm coming home from college so I'm just trying to get back home. One cancellation, two delays, missed one plane by three minutes. Reporter: And on the roads, conditions are deteriorating, and fast. Look at this. In monument, colorado, there were nearly whiteout conditions on the highway. While 50 cars piled up on the slick roads in northern california. We're not sure if a snow storm or hail storm precipitated this ice formation. Reporter: Snow and winds impacting cities like des moines, southern parts of minneapolis and eventually chicago. And it doesn't stop there. In the south, damaging winds, hail and isolated tornadoes are possible tonight into tomorrow. The snow is just starting to come down here in des moines, and from here, to madison, wisconsin, it's incredible to think in the next 24 hours, a foot or more. The wind gusts of 50 miles an hour will make drifts three to five feet just as all holiday travelers hit the road.

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