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Special Seminar: Guosong Hong Postdoctoral Fellow at Harvard University

Topic:

New Windows to Understanding the Brain: From Non-Invasive Optical Brain Imaging Through Intact Scalp to Stable Long- Term Brain Mapping at the Single-Neuron Level

Thursday, March 23, 2017 - 10:00am

Venue:

Durand 450

Speaker:

Guosong Hong (Harvard University)

Abstract / Description:

Nanomanufacturing in the semiconductor industry is driven by our ability to rapidly process and manipulate materials into their required forms. This seminar will highlight some of our work to develop materials for the semiconductor field and beyond. First, core-shell ferrimagnetic nanoparticles (FMNPs) developed for self-assembled magnetic storage media will be presented. While FMNPs are susceptible to magnetically induced aggregation, nanoparticles coated with a diblock copolymer are stable in solution and can easily be processed as thin films. As a result, these core-shell particles are suitable for investigating self-assembly processes for creating prototype magnetic media. Next, a simple and facile strategy for high-throughput directed selfassembly of nanoparticles on lithographically defined substrates via spin-coating will be presented. The two-dimensional arrangements of nanoparticles were formed deterministically in just 30 seconds by the strategic placement of topographical features on a substrate. Finally, the integration of dynamic covalent chemistry into nanoimprint lithography will be discussed. Reversible Diels-Alder chemistry was utilized to transfer features onto an aliphatic polycarbonate film in the presence of a silicon master and heat.

Bio:

Dr. Guosong Hong obtained his B.S. in chemistry from Peking University in Beijing, China in 2008. He then carried out graduate studies with Prof. Hongjie Dai at Stanford University, where his research focused on the development of in-vivo second near-infrared (NIR-II) fluorescence imaging using biocompatible fluorophores such as carbon nanotubes, quantum dots, conjugated polymers and small organic molecules with long-wavelength emissions in the 1,000-1,700 nm NIR-II window. Upon receiving his Ph.D. in chemistry in 2014, Dr. Hong began postdoctoral studies with Prof. Charles M. Lieber at Harvard University, where he has been working on the development and application of syringe-injectable mesh electronics for stable long-term invivo electrophysiology at single-neuron resolution in rodent and primate brain and retina for understanding neural circuit evolution involved in visual perception, learning/memory, and neurodegeneration in stroke. Dr. Hong has received recognitions such as the Stanford Graduate Fellowship, William S. Johnson Graduate Fellowship, Materials Research Society (MRS) Graduate Student Award and the International Union of Pure and Applied Chemistry (IUPAC) Honorable Mention Award for Young Chemists. He is currently supported by the American Heart Association Postdoctoral Fellowship.