Genes & Medications

The G.A.P Test analyzes 20+ genes known to affect the metabolism of more than 300 medications. Specifically, our test covers the most studied class of enzymes, cytochrome p450, which are essential for the metabolism of many medications including Plavix and Coumadin, two of the medications for which pharmacogenetic testing is commonly recommended. The following enzymes covered by The G.A.P Test have been scientifically proven to affect a patient’s response to a variety of frequently prescribed drug classes, including beta-blockers and antidepressants.

Comprehensive testing backed by state-of- the-art technology

The G.A.P Test – or Genetic Assisted Prescribing Test – is one of the most comprehensive drug compatibility test on the market, covering 20+ genes, 12 therapeutic categories, and more than 300 medications. With one simple test, you can access a complete genetic profile for your patients, allowing you to confidently prescribe the drug and dose that is best suited for them.

Genes

TherapeuticCategories

Medications

Test development and analysis conducted by leaders in the fields of molecular genetics and personalized medicine. You can feel fully confident in the reliability of The G.A.P Test results.

The G.A.P Test analyzes 20+ genes known to affect the metabolism of more than 300 medications. Specifically, our test covers the most studied class of enzymes, cytochrome p450, which are essential for the metabolism of many medications including Plavix and Coumadin, two of the medications for which pharmacogenetic testing is commonly recommended. The following enzymes covered by The G.A.P Test have been scientifically proven to affect a patient’s response to a variety of frequently prescribed drug classes, including beta-blockers and antidepressants.

Enzymes analyzed include:

Drugs covered:

Anti-Depressant/Anti-Anxiety

aripiprazole (Abilify)

citalopram (Celexa)

desipramine (Norpramin)

doxepin (Adapin, Silenor, Zonalon)

escitalopram (Lexapro)

imipramine (Tofranil)

nortriptyline (Aventyl Hydrochloride, Pamelor)

sertraline (Zoloft)

trimipramine (Surmontil)

venlafaxine (Effexor)

And More

Birth Control

hormonal contraceptives (Ortho Tri-Cyclen, Seasonique, Yasmin)

Cardiovascular

clopidogrel (Plavix)

flecainide (Tambocor)

metoprolol (Lopressor, Toprol-XL, Metoprolo Succinate ER)

propafenone (propafenone systemic)

warfarin (Coumadin, Jantoven)

And More

Endocrinology

simvastatin (Zocor, Vytorin, Simcor)

And More

Gastroenterology

esomeprazole (Nexium, Vimovo)

lansoprazole (Prevacid)

omeprazole (Prilosec, Zegerid, Omesec)

pantoprazole (Protonix)

And More

Hematology

mercaptopurine (Purinethol, Purixan)

thioguanine (Tabloid)

And More

Neurology

phenytoin (Dilantin, Phenytek)

And More

Oncology

capecitabine (Xeloda)

fluorouracil (Adrucil, Carac, Efudex)

irinotecan (Camptosar)

tamoxifen (Nolvadex, Tamofen, Tamoxen)

tegafur (Uftoral, Tegafur)

And More

Pain Management

codeine (Robitussin-AC, Tylenol with Codeine,Cotabflu)

oxycodone (Percocet, OxyContin, Roxicodone)

tramadol (Ultram, ConZip, Ultracet)

And More

Psychiatry

amitriptyline (Elavil, Endep, Vanatrip)

atomoxetine (Strattera)

haloperidol (Haldol)

risperidone (Risperdal)

And More

Rheumatology

azathioprine (Azasan, Imuran)

And More

Personalized medicine is now more accessible and affordable than ever before

The G.A.P Test is the most comprehensive and affordable drug compatibility test on the market. While reimbursement policies for pharmacogenetic testing are continuing to evolve, Medicare and most private insurance companies are now covering The G.A.P Test. Insurance coverage varies by plan and provider, so please encourage your patients to speak with their insurance provider for more information about their specific policy.

The following CPT codes are for your reference if you would like to confirm eligibility in advance.

ABCC11

No code

CYP2C19

81225

CYP2C9

81227

CYP2D6

81226

DPYD

81400

Factor F5 Leiden

81241

SLCO1B1

34695, 34696

TPMT

81401

UGT1A1

81350

VKORC1

81355

A simple report generated with you in mind

Your patient’s G.A.P Test results are made available to you within 3 days via our online portal. In one simple and easy to read report you can see a complete list of your patient’s genetic variations along with a comprehensive assessment of which drugs you should avoid and which are safe to prescribe.

The report starts by highlighting the genetic results for the specific compound requested in the test requisition form so you can quickly see the results of the drug you are most interested in prescribing your patient.

Next, the report lists other drug compounds that may have safety or efficacy concerns for your patient based on their genetic variations.

Specific recommendations for drugs with warnings can be found under the full report. This section provides detail on each drug compound, the related genes and recommendations for prescribing.The report is organized by therapeutic category and is conveniently color-coded for easy warning level identification.