High level of Lipoprotein (a) in the blood linked to heart disease

Lipoprotein (a) is a protein found in the blood that is attached to fat. Researchers
at Cambridge University examined data from an Icelandic study that began in
1967 that measured the level of lipoprotein (a) in 2,047 people who later died
from heart disease, and 3,921 people who did not die from heart disease. After
accounting for factors that are established risk factors for heart disease including
old age, high LDL-cholesterol, and high blood pressure, it was found that people
with a high level of lipoprotein (a) were 60% more likely to develop heart disease
than those with the lowest levels and as the level of lipoprotein (a) increased
so did the risk of developing heart disease. The study is published in the March
24th, 2008 issue of Archives of Internal Medicine.

EPA from fish oils improves major depressive disorder significantly
and when combined with fluoxetine the improvement may be very good

In this newly published study 60 patients with major depression (based on DSM-IV
criteria and a score of 15 or more on the 17-item Hamilton Depression Rating
Scale giving the diagnosis of major depressive disorder) were randomly assigned
to receive EPA, one of the two major fats in fish oils, at a dosage of 1000
mg a day, or the drug fluoxetine (the generic name for the antidepressant drug
Prozac), or they received both (EPA + fluoxetine) all for 8-weeks. At week 4
there was a distinct difference between groups. Fluoxetine decreased the level
of depression by 50% when used alone, EPA reduced the level of depression by
56% when used alone, and when the two were combined (fluoxetine plus EPA) depression
improved by 81%. The study is published in the March 2008 issue of the Australian
and New Zealand Journal of Psychiatry.

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