What of all the other programs that are installed to the 'Program Files' folder, including games and whatnot? Is MS singling out certain operations?
May be another reason I never go with Vista, if this is true!!

So far both instances of F@H are chugging right along and it looks like the 2 w/u's will finish tomorrow sometime.

However, there is something strange going on...I have both instances of F&H installed as non-auto starting. I did put an icon on the desktop for each one..and when I start them up, the 1st one starts fine. When I click on the 2nd one, for some reason it thinks it is the 1st copy, and quits. I then double click on the 2nd copy icon again, and it loads and runs fine.

What is that all about? Related to not putting F@H in the Program Files folder??

Make sure your "machine IDs' are set correctly. I did not see this info in the thread.
The first instance should be machine ID 1 and the second should be machine ID 2, and so on. I run four on my quad and no problems.

Something is still messed up here....just cannot get it to run correctly at all. I guess Vista doesn't like F@H or vice versa. Machine ID's were set right, (1 & 2) but for whatever reason I can only get one instance to run at a time.

I deleted everything (the F@H uninstall program leaves a lot of stuff in the registry - so I manually deleted all of those things as well) and I guess I'll just fold on the XP laptop for now.

You could try copying over the [client.cfg] file from one setup to the other. Just ensure that the 'machine ID' is changed for the second setup. Whichever file is larger, use that. Do the copy only when the programs aren't running.

All seems to be running fine now. On another thread someone mentioned how only one GUI instance can run at a time, regardless of how many cores you have.

To be completely sure, I searched the registry and deleted all references to Pande, etc. that I could find (the uninstall program leaves a lot behind!) and then started all over. I did use the option to run the program as an administrator during install, so that might have helped as well.

Ah, yes! Only one graphical client can run at one time! Should not have assumed that there were two console clients working!
That is why I prefer the console versions.. no interaction, each a separate entity!