"Based on these findings in animal models, our colleagues at the MGH Cancer Center have initiated a clinical trial to test whether losartan can improve treatment outcomes in pancreatic cancer."

"Angiotensin inhibitor are safe blood pressure medications that have been used for over a decade in patients and could be repurposed for cancer treatment," explains Rakesh K. Jain, PhD, director of the Steele Laboratory for Tumour Biology at MGH and senior author of the study.

Story continues below...

Lowering Your Blood Pressure

Lowering Your Blood Pressure

1

of

6

Share this slide:

"Unlike anti-angiogenesis drugs, which improve tumour blood flow by repairing the abnormal structure of tumour blood vessels, angiotensin inhibitors open up those vessels by releasing physical forces that are applied to tumour blood vessels when the gel-like matrix surrounding them expands with tumour growth."