Duets: The Final Chapter (sometimes referred as The Biggie Duets) is the final posthumous remix/studio album featuring hip hop icon The Notorious B.I.G.. The album was released by Bad Boy Records on December 20, 2005 and charted at #3 selling 438,000 copies, beaten by the extremely high sales of Jamie Foxx's Unpredictable and Mary J. Blige's The Breakthrough.[1] In the UK it climbed as high as #13 after the release of the album's first single "Nasty Girl". It is his third posthumous album that went Double-platinum and is said to be his last album of mainly new material.

The album featured orchestrated duets between Biggie and a number of popular rappers and singers, much like the previous LP Born Again (1999). Biggie's lyrics come from studio pieces of some of the songs he created during his life (his verse from "Notorious Thugs" in "Spit Your Game"), along with some less common lyrics (a freestyle from a promotional tape on "Hustler's Story"), & unreleased material (Biggie's verse in "Living in Pain" comes from an unreleased song from Ready to Die called "House of Pain") all remixed into duets. The package also included a DVD featuring previously unreleased performance footage and several of Biggie's music videos.

The album's first single was "Nasty Girl", featuring P Diddy, Nelly, Jagged Edge, Avery Storm, Jazze Pha and Fat Joe. It took Biggie's vocal samples from his song "Nasty Boy". The single climbed to #1 in the UK in its second week of release, where it stayed for 2 weeks and became his first and only #1 single there. The single also helped the album climb to #13 and therefore, Duets: The Final Chapter became his highest charting album to date there, out peaking the #23 position of Life After Death. In the US, "Nasty Girl" made #45 on the Billboard Hot 100 and the single also made the top 20 in Australia.

The second single from the album is "Spit Your Game", featuring Twista and Krayzie Bone, a double A-side single with "Hold Ya Head", a duet with Bob Marley, which was originally the b-side to "Nasty Girl" in the UK and Australia. "Spit Your Game" is a remake of the Biggie song "Notorious Thugs". "Hold Ya Head" was produced by Clinton Sparks, and features a sample from the Marley song "Johnny Was". It features Biggie's vocal samples from "Suicidal Thoughts".