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A Welsh Ambulance Service spokesman said: "The Wales Air Ambulance, a paramedic in a rapid response vehicle, and three crews in emergency ambulances attended the scene.

"Two patients have been taken to hospital; a man has been airlifted to Ysbyty Gwynedd in a serious condition, while a woman has been taken by road to Ysbyty Glan Clwyd with non-life-threatening injuries."

A man was flown to Ysbyty Gwynedd following the incident (Image: Arwyn Roberts)

A North Wales Fire and Rescue Service spokeswoman said the crash involved a tractor and two trailers.

"We attended to make the vehicles safe and to help assist the ambulance service," said the spokesman.

The road was re-opened at roughly 6.45pm.

Anybody with information is asked to contact officers at the Roads Policing Unit in Llandegai on 101, quoting reference number V090448.