Febrile neutropenia is having a fever of ≥38.3 ºC or ≥38 ºC over an hour and neutropenia that is having an absolute neutrophil count (ANC) of <500 neutrophils/mm3 or an ANC <1000 neutrophils/mm3 expected to decline to ≤500 neutrophils/mm3 over the next 48 hours.
The risk of febrile neutropenia is directly proportional to the duration and severity of neutropenia.
Fever is frequently the only indication of infection in the neutropenic patient.

Consider viral cultures of mucosal or cutaneous vesicular or ulcerated lesions and of throat or nasopharynx for respiratory symptoms especially during outbreaks

Chest X-ray for patients with respiratory symptoms or if outpatient management is planned

Consider urinalysis, pulse oximetry

In urinalysis, absence of pus cells does not rule out a urinary tract infection in neutropenic patients

Tests for viral infection such as polymerase chain reaction- and direct fluorescence antibody-based tests may be considered

Risk Assessment

Risk assessment for complications of severe infection is done at the first sign of fever, guiding the type of empirical antibiotic treatment [oral vs intravenous (IV)], treatment setting (outpatient or inpatient), and the duration of antibiotic treatment

Tools Used to Identify Appropriate Site of CareTalcott's Rules

A predictive tool used to identify patients eligible for outpatient management

A wristwatch-like device that monitors pulse, breathing and blood oxygen levels of the user allows physicians to provide care remotely both in hospital and nontraditional settings, and may help in the fight against the coronavirus disease 2019 (COVID-19) pandemic.

The use of a vaginal cleansing intervention prior to Caesarean delivery reduced the incidence of surgical site infections (SSIs), according to a study presented at ACOG 2020. However, the addition of intravenous (IV) azithromycin prophylaxis had no added impact on SSI rates.

Persons suffering from asthma should pay particular attention to SARS-CoV-2 precautionary measures such as social distancing, regular handwashing, and wearing of masks on top of keeping their asthma in control. This is because data collected so far paints a bleaker picture for asthmatics than the normal population should they catch COVID-19.

A comprehensive review of neurological disorders reported during the current coronavirus disease 2019 (COVID-19) pandemic demonstrates that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the central nervous system (CNS), the peripheral nervous system (PNS) and muscles, leading the Environmental Neurology Specialty Group of the World Federation of Neurology to propose implementation of international neurological registries.