silence

blue wall of silence

An unspoken policy of concealment by police regarding the wrongdoing or illicit activity of other officers. Primarily heard in US, South Africa. I respect the need for the police, but it's hard to trust them completely when so many stories of the blue wall of silence come to light.

blue code of silence

An unspoken policy of concealment by police regarding the wrongdoing or illicit activity of other officers. Primarily heard in US, South Africa. I respect the need for the police, but it's hard to trust them completely when so many stories of the blue code of silence come to light.

code of silence

The practice of not disclosing important or vital information by members of a group, as due to the threat of violence, reprisal, being branded as a traitor, or an inherent sense of honor. There are parts of the city where the code of silence is so strong that police don't even bother questioning the residents there.

conspiracy of silence

An agreement, either explicit or unspoken, among members of a group to keep secret certain information that, if exposed, could be damaging to the group, its interests, or its associates. Knowing that public knowledge of their imminent takeover by the rival company could jeopardize their continued employment thereafter, the board of directors agreed to a strict conspiracy of silence until the deal was finalized.The doctors in the hospital were engaged in a tacit conspiracy of silence, as each knew that bringing to light their colleague's misbehavior could end up damaging their own reputations in the process.

deafening silence

A conspicuous and striking lack of noise or sound. Jim's proposal was met with deafening silence at the meeting.After living in the city all my life, I can't stand the deafening silence of the countryside.

silence means consent

If you do not voice your objection to something, then it is assumed that you support it. A: "Why did you think I would agree to punishing a student so harshly?" B: "Well, you didn't say anything when we originally discussed this plan! Silence means consent."Make sure to speak up when you disagree with something, because, for many people, silence means consent.

speech is silver, silence is golden

wall of silence

1. An unspoken policy of concealment by police regarding the wrongdoing or illicit activity of other officers. A variation on the phrase "blue wall of silence." I respect police, but it's hard to trust them completely when so many stories of the wall of silence come to light.

2. Constant silence, often due to unhappiness or secrecy. Ever since my husband found out that I lied to him, there's been a wall of silence between us.Mom can never know that I broke her vase, OK? There's a wall of silence, starting now.

break (one's) silence

1. To voice one's opinion or comment on something after initially avoiding doing so. It took days, but the mayor has finally broken his silence on the scandal at city hall.

2. To address or publicize an issue that is not garnering attention. A noun is not used between "break" and "silence" in this usage. Our station broke silence on the mayor's scandal, and now even national news outlets are covering it!

reduce someone to silence

Silence gives consent.

Prov. If you do not object to what someone says or does, you can be assumed to agree with or condone it. Jill: What did Fred say when you told him we were thinking about leaving the office early? Jane: He didn't say anything. Jill: Then he must not mind if we go. Silence gives consent.

conspiracy of silence

A tacit or explicit agreement to keep something secret. For example, In this state's medical society there is a conspiracy of silence regarding incompetent practitioners . This term was first used as a complaint about lack of attention, but today it more often refers to remaining silent about something unfavorable or criminal. [Late 1800s]

silence is golden

Keeping one's mouth shut is a great virtue, as in Don't tell anyone else about it-silence is golden. Although this precise phrase was first recorded only in 1848, it is part of a much older proverb, "Speech is silver and silence is golden."

a conspiracy of silence

If there is a conspiracy of silence, people who know about something have agreed that they will not tell anyone about it. Detectives have run into a conspiracy of silence in the close communities here.

silence is golden

a conˌspiracy of ˈsilence

an agreement not to talk publicly about something which should not remain secret: As no one was ever convicted of the murders, it is widely believed that there may have been a conspiracy of silence maintained by the victims’ friends and families.

The team also studied the importance of tryptophan residues to p19's silencing suppression effects by introducing mutations into the p19 coding sequence of the CIRV genome to change one or both of the tryptophan residues.

In vivo systemic administration of ALN-PCS01 in mice was associated with dose-dependent and rapid silencing of the PCSK9 messenger RNA to more than 70 percent of control levels, with peak silencing effects observed as soon as 48 hours after dosing.

They identified, described, and named the "Dicer" enzyme, which chops dsRNA into siRNAs, as well as the RNA-induced silencing complex (RISC), which mediates the silencing process by degrading the homologous mRNA.

In a poster titled "Widespread distribution of siRNAs targeting Huntingtin in the CNS after chronic intrastriatal infusion," Alnylam and Medtronic presented pre-clinical data demonstrating that siRNAs specific for the huntingtin gene, which is mutated in Huntington's disease, were administered in vivo to achieve silencing of the disease-causing gene.

Despite the rapid advance of RNAi gene silencing for drug discovery and development, some research has been hampered by the insufficient delivery of siRNA into primary cells and non-standard cell lines.

demonstrated silencing in primates of the gene for apolipoprotein B (apoB), a protein involved in cholesterol metabolism, with clinically significant efficacy as demonstrated by reductions in levels of cholesterol and low-density lipoproteins (LDL).

Nasdaq: ALNY), a leading RNAi therapeutics company, announced today that its research on therapeutic silencing of microRNAs was featured in an article published in the March 16, 2006 issue of The New England Journal of Medicine.

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