Target Details Kallikrein 11

Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of hK11 were found in 70 % of women with ovarian cancer and in 60 % of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.Synonyms: Hippostasin, PRSS20, Serine protease 20, TLSP, Trypsin-like protease, hK11

Application Details

ELISA. Western Blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 5 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.