Ralph Lauren quietly shuttered its two-year-old 20,000-square-foot store last week. Other brands are expected to close boutiques in a city that has lost its luster for cash-rich mainland Chinese tourists.

Most brands were affected, though midsize magazines — Self and Brides — were hardest hit. Pink slips even went out on the 18th floor, at the corporate communications office, where two staffers, including a corporate vice president, Susan Portnoy, were let go.

The layoffs, which began Wednesday morning and continued through Thursday, came after Condé, which owns WWD, had already asked brands to cut back 10 percent off their annual budgets. The latest round of cuts are related to next year’s business plans.

On Thursday afternoon, after a grim day at 4 Times Square, chief executive officer Charles Townsend sent an internal memo attributing the layoffs to “the challenges of the U.S. economy.” He said no additional announcements related to next year’s budget are expected.

At Self, eight editorial and three business staffers were let go, WWD confirmed; the layoffs at the magazine and corporate communications were first reported by the New York Post.

Condé Nast Traveler, GQ and Wired each lost at least one editorial staffer, sources said. It’s not clear what other positions throughout the company were eliminated.

Portnoy had been with Condé for more than six years, and as part of her portfolio, she also handled media relations for Fashion’s Night Out. A decision has not been made as to who — corporate communications or Vogue — will play that role in next year’s event.

Portnoy’s duties in the corporate office will now fall to a senior vice president, Patricia Steele. Though no final decisions have been made, the office itself, overseen by chief administrative officer Jill Bright, may be reimagined to focus more broadly on corporate branding.

WWD's Ultimate Holiday Gift Guide is brought to you by @styleontherise and is complete with the perfect presents for everyone on your list. Click the link in our bio to start shopping NOW. #WWDHoliday #Sponsored

@rebeccaminkoff is bringing self-checkout to high fashion: The brand has partnered with @queuehop to bring its customers self-checkout options, beginning this holiday season at its SoHo store. (📷: @aurorarosephoto)