The clinical prediction rule that may predict safe discharge is as follows:

1) can mobilize as usual; 2) have oxygen saturation on room air of >92%; 3) have a respiratory rate >10 breaths/min and <20 breaths/min; 4) have a temperature of >35.0 degrees C and <37.5 degrees C; 5) have a heart rate >50 beats/min and <100 beats/min; and 6) have a Glasgow Coma Scale score of 15

We conclude that if the patient demonstrates all six features carefully applied WITH the caveat that there be no verbal or tactile stimulation prior to the evaluation, then the patient is likely to be safe to discharge after reversal with naloxone. This concept has not been strictly tested in the literature, but the article in Clinical Toxicology supports this practice. And now on to the podcast … let us know what you think!