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Pruritus Medical Research Studies

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Up-to-date List of Pruritus Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Change from Baseline to the Evaluation Period (weeks 7 and 8) in itch on the 0-10 Itch Numerical Rating Scale; Change from Baseline scores to the Evaluation Period (weeks 7 and 8) in the total Skindex-10 score

the percentage change in pSTAT3 expression among patients reporting a relief in their Pruritus, irrespective of lesion clearing; IL-31 amount and intensity of cathepsin S expression; percentage of vasodilatory peptidergic nerves at the dermoepidermal junction as a percentage of total nerves

A description of the overall incidence frequency and nature of Treatment Emergent Adverse Events (TEAEs); A description of the incidence frequency and nature of Treatment Emergent Adverse Events (TEAEs) during Treatment by achieved dose

• To determine whether CT327 is effective in reducing Pruritus in subjects with atopic dermatitis, using a Pruritus visual analogue scale (VAS); • To assess efficacy of CT327 on atopic dermatitis using the Investigator Global Assessment (IGA)

These studies may lead to new treatments and are adding insight into Pruritus etiology and treatment.

A major focus of Pruritus research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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