BACKGROUND

NPMRD study group was initially established to support research collaboration between Universitas Airlangga, Indonesia and Kobe University, Japan through JICA/JST SATREPS on 2010. Currently, NPMRD research focused on drug discovery and natural medicine development including efficacy, safety, and quality guaranteed medicine. We combined the best science and technology in the field of pharmacy, chemistry, biology, and medical which supported by reliable equipment and staff.

NMR Mechine

The main program in NPMRD was :

1. Innovative research for the discovery of medicines for infections diseases such as anti hepatitis, antimalarial, antiamoebic, antidengue, etc. and non infection diseases such as hepatoprotective, immunomodulator, and health supplement

2. Laboratory testing and training for public services such as:

•Phytomedicine work including extraction, isolation, and compound analysis using NMR, HPLC, and LCMS/MS QTOF

• Preclinical study:

• Invitro Bioassay work including Invitro assay of malaria, hepatitis, dengue, and amoeba; mechanism assay by ELISA,Western blot, and PCR.

RESEARCH EXPERIENCES

Kobe University and National Institute of Biomedical Innovation (NIBIO), Japan. The research was focused on identification of antiHCV substances and granted by JICA/JST SATREPS (2010-2014). .

Indonesia Military Health Institution (Lakesmil). The research was conducted clinical trial of cempedak capsule product as an alternative complementary drug for malaria prophylaxis at Nanga Badau, Kalimantan (2014).Pharmaceutical company: PT. Kimia Farma (Persero) Tbk, Indonesia. The research is focused on development of sambiloto fraction as antimalarial product and granted by Ministry of Research Technology and Higher Education (2015-2017).The agency for assessment and application of technology (BPPT)-Indonesia;Tsukuba University, The National Institute of Infectious Diseases (NIID)- Japan. The research was focused on utilization of Indonesia resources as antiamoebic and antimalarial. The research granted by JICA/AMED SATREPS (2015-2020)..

OUTPUT

Research collaboration resulted some publications and product prototypes

NMR Mechine

PRODUCT PROTOTYPES

Antimalarial (Capsul of Artocarpus champeden as antimalarial)

Antimalaria2 (Tablet of Andrographis paniculata as antimalarial)

Apphyn (Capsul of Andrographis paniculata and Phyllanthus niruri as immunomodulator)

Bicurmin (Capsul of Curcuma xanthorrhiza and Curcuma domestica as hepatoprotective)

BACKGROUND

NPMRD study group was initially established to support research collaboration between Universitas Airlangga, Indonesia and Kobe University, Japan through JICA/JST SATREPS on 2010. Currently, NPMRD research focused on drug discovery and natural medicine development including efficacy, safety, and quality guaranteed medicine. We combined the best science and technology in the field of pharmacy, chemistry, biology, and medical which supported by reliable equipment and staff.

The main program in NPMRD was :

Innovative research for the discovery of medicines for infections diseases such as anti hepatitis, antimalarial, antiamoebic, antidengue, etc. and non infection diseases such as hepatoprotective, immunomodulator, and health supplement

RESEARCH EXPERIENCES

NPMRD conducted several research collaboration with some national and international institution which are:

Kobe University and National Institute of Biomedical Innovation (NIBIO), Japan. The research was focused on identification of antiHCV substances and granted by JICA/JST SATREPS (2010-2014).

Indonesia Military Health Institution (Lakesmil). The research was conducted clinical trial of cempedak capsule product as an alternative complementary drug for malaria prophylaxis at Nanga Badau, Kalimantan (2014).

Pharmaceutical company: PT. Kimia Farma (Persero) Tbk, Indonesia. The research is focused on development of sambiloto fraction as antimalarial product and granted by Ministry of Research Technology and Higher Education (2015-2017).

The agency for assessment and application of technology (BPPT)-Indonesia;Tsukuba University, The National Institute of Infectious Diseases (NIID)- Japan. The research was focused on utilization of Indonesia resources as antiamoebic and antimalarial. The research granted by JICA/AMED SATREPS (2015-2020).

OUTPUT

Research collaboration resulted some publications and product prototypes.