JERUSALEM — Prime Minister Benjamin Netanyahu of Israel said Friday that his forces were fighting Hamas with “increasing intensity” to quell its rocket barrages from Gaza, ignoring outside criticism and calls for restraint in the increasingly deadly Israeli aerial assaults. Even as he spoke, Palestinian militants fired salvos into central and southern Israel and said their arsenal had barely been dented.

Palestinian deaths from four days of Israeli aerial assaults surpassed 100, with hundreds wounded. As of Friday, no Israelis had been killed by Gaza rockets, although one caused the first serious instance of multiple injuries on the Israeli side since the hostilities intensified.

“No international pressure will prevent us from operating with full force against a terrorist organization that calls for our destruction,” Mr. Netanyahu said in remarks broadcast from a news conference at the Defense Ministry in Tel Aviv.

With the government considering a ground invasion of Gaza, Mr. Netanyahu did not lay out his battle plans but said, “We are weighing all possibilities and preparing for all possibilities.”

No outside mediator has stepped in yet to broker a renewal of the cease-fire that went into effect after the last round of fierce cross-border fighting, in November 2012, and neither side seemed inclined to de-escalate.

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Members of the Abu Lealla family searched the rubble of their destroyed home on Friday after an Israeli airstrike north of Gaza City.CreditWissam Nassar for The New York Times

Mr. Netanyahu said he had held “good talks” over the last few days with the leaders of the United States, Britain, France, Germany and Russia, among others, and said he had told them, “No country would accept its civilians being fired at without a harsh response.”

But in a Middle East already unnerved by the turmoil in Syria and Iraq, regional leaders began to protest loudly.

Outrage was expressed by Prime Minister Recep Tayyip Erdogan of Turkey, whose government had been slowly reconciling with Israel after the deadly Israeli commando seizure of a Turkish vessel trying to breach the blockade of Gaza four years ago.

“We cannot be positive about a normalization process while bombs are raining on our brothers in Palestine, Gaza,” Mr. Erdogan said. He accused Israel of lying about the rockets, because of the conspicuous lack of Israeli fatalities.

In an interview with the NBC program “Meet the Press” to be broadcast on Sunday, the Iranian foreign minister, Mohammad Javad Zarif, called for “an immediate end” to Israel’s aerial attacks on Gaza, declaring “the United States and the rest of the members of the Security Council have a moral and legal responsibility to put an end to this.”

In Geneva, the United Nations high commissioner for human rights, Navi Pillay, urged Israel “to take all possible measures to ensure full respect for the principles of distinction, proportionality and precautions” in avoiding harm to civilians.

In an emergency appeal for funds, the World Health Organization said the hostilities had exacerbated an already stressed Palestinian health system, particularly in isolated Gaza.

The organization cited shortages of medicines, other medical supplies and hospital fuel. The organization’s Regional Office for the Eastern Mediterranean added in a statement that a hospital, three clinics and a water desalination facility in a refugee camp had been damaged in Gaza.

The Health Ministry in Gaza said that 103 Palestinians had been killed in the Israeli air campaign by Friday evening, many of them civilians including women and children. One of the latest victims, Saher Abu Namous, 3, was killed in a strike in the Tal al-Zatar neighborhood.

The Israeli military says it has struck more than 1,100 locations in Gaza such as rocket launchers, weapons stores and, more controversially, what it describes as command and control centers run by Hamas and Islamic Jihad operatives in private homes. Israel says it first advises the occupants to vacate, using telephone alerts and unarmed missiles that strike the premises in a warning of the destruction to come. But five members of a family were killed in a strike on their home in the southern city of Rafah at dawn on Friday.

Israel blames the militant groups, saying they hide behind Gaza’s civilians. “The difference between us is simple,” Mr. Netanyahu said. “We develop defensive systems against missiles in order to protect our civilians and they use their civilians to protect their missiles.”

The intensity of the aerial attacks has been double that of the eight-day round of fighting in 2012.

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The Israeli prime minister said international pressure would not prevent him from pressing forward with a broad military offensive in the Gaza Strip.CreditCreditGali Tibbon/Agence France-Presse — Getty Images

At the same time the barrages of rockets launched by Hamas and Islamic Jihad have reached much deeper into Israel than in the past and hit new targets spread across a wide area. More than 140 rockets were fired into Israel on Friday.

Several were intercepted above the Tel Aviv area by Israel’s Iron Dome missile defense system. One rocket hit a gasoline station in the Israeli Mediterranean port city of Ashdod, setting it ablaze. Israel’s ambulance service said eight people were hurt, including a 61-year-man who suffered severe wounds.

Later Friday a rocket hit a house in the southern city of Beersheba, injuring a woman, according to the military.

Israeli officials say that Hamas has been frustrated by the lack of Israeli fatalities so far. On its website, Hamas’s military wing said it was ready for a long fight.

“So far Hamas has utilized only a little of what it has prepared for the Zionist enemy,” the group said. “We have prepared ourselves for a very long battle,” it added, “not for a week or 10 days, as some have said, but for many long weeks.”

In another ominous signal, a rocket was launched from Lebanon that struck open ground in northern Israel, putting Israeli forces in the north on alert and raising the specter of confrontation on a second front. An Israeli military official said it was too early to determine whether the act was “symbolic or something more substantial.”

Israel responded with artillery fire aimed at the launch site in Lebanon, according to Lt. Col. Peter Lerner, a spokesman for the Israeli military. He said it was not immediately clear whether Hezbollah, the Shiite organization against which Israel fought a 34-day war in 2006, was responsible for the rocket fire from Lebanon.

Isabel Kershner reported from Jerusalem, and Fares Akram from Gaza. Rick Gladstone and Somini Sengupta contributed reporting from New York, and Sebnem Arsu from Istanbul.

A version of this article appears in print on , on Page A7 of the New York edition with the headline: Israeli Leader Calls for ‘Full Force’ in Effort to Quell Hamas Rocket Attacks. Order Reprints | Today’s Paper | Subscribe