Coriander has long been used by humans as a traditional drug and to enhances the taste of foods. This study aims to know the effects of coriander ethanol extract against phagocytosis activity and capacity of the macrophage cells and the percentage of leukocytes. The test animals used were white male mice which divided into 4 groups and each group consists of 5 mice. The first group (control) was given with 0.5% Na CMC suspension. The second, the third, and the fourth groups were given with coriander extract each with doses of 100 mg/kg, 140 mg/kg and 200 mg/kg orally for 7 days long. On the 8th day, the mice were induced by Staphylococcus aureus to help their immune system. The results showed that the administration of coriander extract at doses of 100, 140 and 200 mg/kg can increase the phagocytic activity of macrophages by 44.6%; 54.2%; and 60.2% each, while the phagocytic capacity replaces the results of 95.8; 104.4; and 126 cells. The total number of leukocytes showed were 5210, 6190, and 7310 /μL blood. In the number of leukocyte cells, the amount of coriander extract can reduce the number of neutrophil and monocyte cell segments. The conclusion of this study regarding coriander ethanol extract at doses of 100, 140 and 200 mg/kg can increase phagocytosis activity and capacity of the macrophage cells and the total leukocyte cell counts in male white mice.

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Pharmacognosy Journal (Phcog J.) covers different topics in natural product drug discovery, and also publishes manuscripts that describe pharmacognostic investigations, evaluation reports, methods, techniques and applications of all forms of medicinal plant researchDistinctions: The most widely read, cited, and known Pharmacognosy journal and website is well browsed with all the articles published. More than 50,000 readers in nearly every country in the world each monthISSN : 0975-3575 ; Frequency : Rapid at a time publication (6 issues/year)Indexed and Abstracted in : SCOPUS, Scimago Journal Ranking, Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Index Copernicus, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS.Rapid publication: Average time from submission to first decision is 30 days and from acceptance to In Press online publication is 45 days.Open Access Journal: Pharmacognosy Journal is an open access journal, which allows authors to fund their article to be open access from publication.

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