Lincoln Six-Echo (Ewan McGregor) and Jordan Two-Delta (Scarlett Johansson) are residents of a contained facility in the mid-21st century. All the inhabitants in the facility hope to be chosen to go to 'The Island', which is the last uncontaminated spot on the planet. But they soon discover that everything in their lives is a lie and that they are actually clones, so they break out and are now being pursued by forces of the institute.