1. When an individual (usually a male), has courage enough to attempt a dangerous feat.

2. When an individual steps out of line, especially with an individual much more intimidating than them self.

3. When an individuals testicles grow to monstrous size due to genetic mutation.

1. That guy has a serious case of testicular elephantitis, he just jumped over a moving car!
2.That asshole must have a case of testicular elephantitis to fuck with me!
3. I went to the doctor, and was diagnosed with testicular elephantitis...