The EPA Administrator is customarily accorded Cabinetrank by the President and sits with the President, Vice President, and the 15 Cabinet Secretaries. Since the late 1980s, there has been a movement to make the Administrator of the Environmental Protection Agency a Cabinet Secretary, thus making the EPA a 16th Cabinet department, dealing with environmental policy. The Administrator of the EPA is equivalent to the position of Minister of the Environment in other countries.

President Trump's first EPA Administrator, Scott Pruitt, resigned effective July 6, 2018, amid a series of scandals. Deputy Administrator Andrew Wheeler, a former coal industry lobbyist, started serving as acting administrator on July 9, 2018.[1]

Note that Acting Administrators usually assume the office in the interim period between the resignation of a previous Administrator and the confirmation of his or her successor, including during the transition period between two presidential administrations, before the successor has been nominated and confirmed. Acting Administrators come from within the EPA and usually hold an office that is subject to Senate confirmation before becoming the Acting Administrator. Linda Fisher and Stephen L. Johnson had served as Deputy Administrator when they became Acting Administrator. Marianne Lamont Horinko was an Assistant Administrator at the time. They are not subject to Senate confirmation to serve as the Acting Administrator, though to continue to serve as a full-fledged Administrator (as in the case of Lee M. Thomas or Stephen L. Johnson), they must be confirmed by the Senate.