Micro-volume Protein Analysis

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Avacta Analytical unveiled the Optim 2 micro-volume protein analysis and characterization instrument. This system combines the protein characterisation capabilities of the original Optim 1000 instrument with a new, application-oriented software package designed to increase throughput and functionality. The newly developed system, which has a greatly reduced footprint, features an enhanced sample positioning system to offer even greater measurement accuracy and reproducibility, and has been designed to simplify servicing and maintenance for maximum uptime. The Optim 1000 was developed to reduce the time and cost of therapeutic protein formulation studies and protein stability testing by offering simultaneous measurement of a range of protein stability indicating parameters, including unfolding transition temperature (Tm) and aggregation onset temperature (Tagg). The Optim 2’s control software has been developed around common protein development workflows, offering quick and easy access to a range of pre-programmed measurement types for faster method development. This is combined with an analytical package that is also compatible with the Optim 1000 to provide a comprehensive and cost-effective solution for stability screening of candidate molecules or formulations much earlier in the development process.