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Senate Armed Services Chairman John McCain, R-Ariz., arrives for votes on Capitol Hill in Washington, Monday evening, Nov. 27, 2017. President Donald Trump and Senate Republicans are scrambling to change a Republican tax bill in an effort to win over holdout GOP senators and pass a tax package by the end of the year.

Republican Sen. John McCain is returning home to Arizona after being hospitalized for the side effects of his brain cancer treatment and likely will miss a crucial vote on the GOP tax package, President Donald Trump said Sunday.

The office of McCain said the senator will undergo physical therapy and rehabilitation at Mayo Clinic in Arizona, and he looks forward to returning to Washington in January.

Trump told reporters he had spoken to McCain's wife, Cindy, after her husband had spent about a week at Walter Reed National Military Medical Center in Maryland.

"They've headed back, but I understand he'll come if we ever needed his help, which hopefully we won't," Trump said. "But the word is that John will come back if we need his vote. And it's too bad. He's going through a very tough time, there's no question about it. But he will come back if we need his vote."

White House Responds to GOP Senator's Critique of Trump

White House press secretary Sarah Huckabee Sanders responded to Sen. Jeff Flake Tuesday after the Arizona Republican announced his retirement in a speech critical of President Donald Trump's “mercurial behavior.”

(Published Tuesday, Oct. 24, 2017)

Sen. McCain has responded well to treatment he received for a viral infection and continues to improve, Dr. Mark Gilbert, Chief of Neuro-Oncology at the National Institutes of Health's (NIH) National Cancer Institute, said in a statement Sunday.

Now in his sixth Senate term, McCain, 81, underwent surgery in mid-July to remove a 2-inch (51-millimeter) blood clot in his brain after being diagnosed with glioblastoma. A statement issued last Wednesday by the senator's office said he was at Walter Reed receiving treatment for the "normal side effects of his ongoing cancer therapy."

His daughter Meghan McCain tweeted Sunday: "My father is doing well and we are all looking forward to spending Christmas together in Arizona."

Republicans hold a slim 52-48 majority in the Senate, and McCain and Sen. Thad Cochran, R-Miss., missed votes last week. The 80-year-old Cochran had a non-melanoma lesion removed from his nose earlier this week. He is expected to vote this coming week on the tax bill.

Republicans secured the support of Florida Sen. Marco Rubio and Tennessee Sen. Bob Corker last Friday. They likely will pass the bill by a narrow margin in the face of unified Democratic opposition. As a backstop, Vice President Mike Pence would be available to break a tie.

After his summer surgery, McCain rebounded quickly, returning to Washington and entering the Senate on July 25 to a standing ovation from his colleagues.

Rubio Says He Won't Support Current Tax Bill Without Changes

Senate Republicans can only afford to lose two votes, and five are in question.

Senators Mike Lee and Marco Rubio are holding out to make more of the child tax credit refundable to low and middle income families.

"Unless they can figure out a way to add to the $1100 figure, I won't support the bill," Rubio says.

(Published Friday, Dec. 15, 2017)

In a dramatic turn, he cast a deciding vote against the Republican health care bill — a move that drew the wrath of Trump and conservatives. McCain's vote scuttled the seven-year effort by the GOP to dismantle much of President Barack Obama's health care law.

But McCain's condition has appeared to worsen in recent weeks. He suffered a minor tear in his right Achilles tendon, forcing him to wear a walking brace. McCain eventually began using a wheelchair, and members of his staff pushed him where he needed to go.

As a Navy pilot, McCain lived through a July 1967 fire that killed 134 sailors aboard the aircraft carrier USS Forrestal in the Gulf of Tonkin during the Vietnam War. The following October, his plane was shot down during a bombing mission over Hanoi. He spent more than five years as a prisoner of war. McCain also has survived several bouts with melanoma, a dangerous skin cancer.