In this article, recommended hair transplant surgeon Dr. Parsa Mohebi shares his research concerning the effects of wound healing on hair growth.

I recently received an interesting inquiry from a patient regarding hair growth following his leg injury. The case reminded me of some of my work at Johns Hopkins University School of Medicine on hair growth and wound healing. I thought this would be an interesting subject for balding men and women who are interested in the latest techniques of hair restoration. The subject could also be of intrigue for doctors who thrive on developing new ways to help their patients through the means of quality hair restoration research.

This patient explained a condition in which he noticed brand new hair which appeared to be growing out of a healing wound he had as a result of a biking injury. The patient found this discovery to be fascinating and wondered what scientific studies have recorded cases of this type, and how his predicament can be seen as a benefit to science.

When doing research on wound healing at Johns Hopkins University, our team did research on an animal model which revealed to us that wound healing can enhance the growth of hair. This result came as a shock when looking at different wound healing studies. It was noted there were gene therapy techniques which may have possibly affected the hair growth in the animals being studied.

Following our astonishing finding, a second set of experiments were designed and performed in response to the question, “What has been the effect of wound healing on the growth of hair”. We have tried to isolate the specific mechanism which caused the new hair to grow. It was obvious during those observations that, when skin is wounded, hair has the potential to grow thicker and faster in the wounded areas. Click image below for larger view.

Before we could publish our results a team from the University of Pennsylvania published an article in Nature in 2007, based on a study they had done on an animal model regarding wound healing and hair growth. This team was led by Dr. George Cotsarelis and the article explained how a piece of hair in mammals is like a “mini organ” which is believed to be gone permanently when removed. What was discovered in mice is, when some of them were wounded, as their wound was healing, stem cells formed around the healing area which created brand new hair follicles. This phenomenon has provoked many questions as to the possibilities of new hair growth through wound healing and stem cells.

When looking at the patient inquiry combined with the studies at both the University of Pennsylvania and our work at Johns Hopkins University, there is a possibility for new findings which can revolutionize the current understanding of hair regrowth and stem cells. These studies have never been duplicated in humans but, if the same mechanism which worked in the animal models works in humans, new and greater possibilities are in the near future.

The key for future study on this subject is to examine the different variables going into the case study. Every piece of the puzzle may contribute to the overall reasons for the new hair growth. In the end, there is a world of possibilities which may be closer to our reach than previously thought. Good experimentation and proper documentation may help this journey move along to greater depths of understanding and can benefit the world of hair restoration with better quality and more available options for the treatment of hair loss..

12 Comments

Gary Hitzig MD
October 26, 2011 @
12:29 pm

This same idea is what we have been incorporating with the use of ACell during hair transplant procedures. ACell (Matristem) attracts Adult Stem Cells to the site of injury (in this case Hair Transplantation) and converts them into active progenitor cells which is what becomes missing during hair miniatuization. It also sets up a non crosslinked temporary scaffolding for the tissue reconstruction mimicking the surrounding healthy but damaged tissue. This scaffolding contains and slowly releases growth factors (VEGF etc.). The Acell also contains an abundance of necessary materials for remodeling including Collagen IV.
This process has resulted in increased hair counts in the grafts in the recipient area (increased hair density) plus remarkable healing in the donor area.
Using a biphasic ECM I believe is paramount to achieving these results which will be published in the next two months.

janet s. porges
April 25, 2013 @
8:42 am

FYI: I had a bike accident in February resulting in a 6″ hematoma on the shin, the contents of which were evacuated two weeks later using a liposuction cannula. This incision was the only breach of the skin itself. There is superficial nerve damage (loss of touch sensation) and a small area immediately over the shin which lost blood supply and appears discolored – due to necrosis?
Since menopause I have had no visible hair on my legs. I was more than surprised to find large hair growth (as in my fecund days!) around only the site of the hematoma itself. I wondered if this phenomena was due to the processes described in your website.
In any event, I didn’t know if this would be of interest to your studies.

ray
October 22, 2013 @
5:49 pm

This article sounds like its going to take another 50 years to come up with a solution. Even if there was cure by now they wouldn’t let it be out of all those hair transplant and hair product companies will go out of business which they make millions of dollars every year and that way FDA will lose money too.
Unfortunately the ones that have hair don’t care about those going bald and those companies knowing people going bald is the least thing they care about.
:-$

Kevin
October 16, 2014 @
10:38 am

I have been thinning on top since college. I am now 34 years old and have a sizable bald spot on the crown of my head and the front is getting very thin. I recently scraped my head getting in a tractor and as the wound healed, I noticed hair growing from the wound. It is very thick and growing very fast. It prompted me to browse the internet for similar instances and I found this article. I would be interested to know if there have been any new advances in this work. My wife wishes I had scraped my whole head.

David aka - TakingthePlunge
October 22, 2014 @
2:31 am

Kevin,

That’s very interesting. The last update that I’m aware of was published in June of 2013. Of course, even if the research in this field is continuing, it will likely be many years before a treatment is available to the public.

Just had an injury to my left arm 3 months ago and just realized the same phenomenon of sudden new growth surrounding the injury but not on the scar itself. I’m concerned since it’s a thick dark patch of hair on and around my elbow that does not coincide with the minimal thin blonde hair on my arms. Is there any way to make this stop? I did lose partial feeling in and around this area. Not sure if getting and being treated for staff infection to the injury had anything to do with it or the cocktail of meds I was given as result.

Tom
March 19, 2015 @
7:21 pm

I just recently experienced a muscle contusion and hematoma on my left leg about 11 days ago. My legs have only microscopic hair, but since 4 days ago when I started a 7 day regimen of levofloxacin to treat the cellulitis that accompanied the hematoma, a few very long, fine hairs started to rapidly grow near the apparent center of the hematoma.

Pat
May 20, 2016 @
10:24 am

I had a knee replacement and noticed an area near the incision that had suddenly grown a thick patch of hair. I have had very little hair growth on my legs for many years. It continued to grow fast and thick for several months. It is now pretty much back to normal. This seems to reinforce the wound healing theory and hair growth.

Nina
July 1, 2016 @
2:38 am

Hi all,
Im am an asian woman and never have to shave my legs. They are just hairless naturally. I survive a terrible bus accident without a scratch. However, out from the only bruise as big as the tip of a pinky on my right leg, a thick and stubborn strand hair grew. No matter how many times I remove it with a tweezer, it keeps coming back. I should just ignore it but it really bothers me so much. Is it abnormal that hair comes out of a bruise?

Thanks,

Nina

Gary
January 29, 2017 @
12:23 am

Had the same thing happen to me. Badly scrapped both knees a few months ago and now the scars have thick hair in and around them. I’ve been bald since my early 20’s but I don’t have it in my scrape my head to find out if it would be the miracle cure!

Eddie
April 5, 2018 @
3:23 pm

Funny. I had something similar after a major back surgery . I had a bit of hair fuzz growing at my lower back that they shaved for surgery. It was narrow band across the whole back and pretty short. It’s seven months post surgery and I have long straight hairs growing just out of the incision site. Probably 2 inches long along the 4 inch incision. . The rest of my back is pretty bare. They glued the top of the incision in case that could have something to do with it.

Cristina
June 11, 2018 @
10:20 am

I just had knee replacement surgery 6 weeks ago and have a 9inch scar on my knee into my thigh. There are very dark hairs growing rapidly alongside the scar. My other leg, in comparison has nothing, maybe a couple fine blonde hairs here and there.