IMPUTE

IMPUTE is a
program for estimating ("imputing") unobserved genotypes in SNP
association studies. The program is designed to work seamlessly with
the output of the genotype calling program CHIAMO
and the population genetic simulator HAPGEN,
and it produces output that can be analyzed using the program SNPTEST.
There are currently three different versions of the IMPUTE
software available for download: version 0.5
implements the methodology described in Marchini et al. (2007);
version 1
is essentially the same as version 0.5, with a couple of added
features; and version 2
implements a major extension that was introduced in Howie et al. (2009).

To go to the webpage for a particular version of the program,
just click the corresponding link below. Or, click the
Background link to read a short description of what each version
of the program does.