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Abstract

To the Editor: Acute rhabdomyolysis can be caused by various drugs, usually by overdosing (1-4). However, cases resulting from isoniazid therapy have not previously been reported. A 25-year-old obese black woman had begun voiding dark brown urine for 4 days before admission (this lasted 2 days and subsided after forcing oral fluids). She also had bilateral calf pain and general malaise that started two days preceding admission and had had a sore throat for 2 days approximately 2 weeks before admission. She had no history of other symptoms of upper respiratory infection, fever, arthralgias, rash, or cough, and no gastrointestinal