So windows autorun is dead, which is probably for the best security-wise. I've heard autorun scripts have been a security threat on Linux machines as well. However, there are still some legitimate reasons to want a USB stick to autorun. Here are some examples:

You have a USB drive you want to sync with local files (eg. Dropbox folder) for offline mobility.

The portable device has an encrypted partition you want to automount on certain machines.

Instant deployment of anti-malware software

After a little bit of google-fu, I found USBDLM which can set custom autorun drive settings on specific computers, but I was wondering if the community had any experience with other autorun hacks (registry edits, handshakes, etc) or auto-syncing a USB drive on insertion.