High nuclear expression of GS28 is associated with poor prognosis in early-stage cervical cancer patients. GS28 might be a novel prognostic marker and a potential therapeutic target in cervical cancer treatment.

Golgi vesicles, presumably with COPI, serve to inhibit intra-Golgi transport by the extraction of GS27 (zeige GOSR2 ELISA Kits) and GS28 from the Golgi cisternae, which blocks the formation of inter-cisternal connections

GS28 may potentiate cells to DNA-damage-induced apoptosis by inhibiting the ubiquitination and degradation of p53 (zeige TP53 ELISA Kits).

Golgi SNAP Receptor Complex Member 1 (GOSR1) Antigen-Profil

Beschreibung des Gens

This gene encodes a trafficking membrane protein which transports proteins among the endoplasmic reticulum and the Golgi and between Golgi compartments. This protein is considered an essential component of the Golgi SNAP receptor (SNARE) complex. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.