South Australia's licence to host the event expires in two years and the State Government is concerned about a potential interstate takeover.

The Tour Down Under was first held in 1999 in South Australia and was awarded ProTour status in 2007, the first event outside Europe to receive such recognition.

Fears it could be poached by Victoria have increased as the profile of the race has grown.

Gaudry says future hosting rights will be open to bidders but says the Tour has a strong track record in South Australia.

"I'll be looking at the whole landscape of cycling in Australia and when you look at the future of events like the Tour Down Under, it's like any major business proposition when a term comes to an end and there may well be a bidding opportunity," she said.

"Track record has a hell of a lot to do with the future of an event and I would suggest that the Tour Down Under has an immense track record and it has that to continue over the next couple of years."

She says having it is natural for South Australians to feel uneasy about no longer having race director Mike Turtur on the UCI board.

"It has been quite neat that the Oceania president [Mike Turtur] happens to be the race director of the Tour Down Under so naturally in any business environment you would feel nervous that the governing body doesn't have one of your ilk sitting inside it."

Premier Jay Weatherill said on Tuesday there was a significant chance Victoria could make a bid for the race.

"We think that they are up to something. We've noticed that they've changed the configuration of some of their events," he said.

"We know that they would love this event and we're very keen to hang on to it and we'll do everything we need to to secure this event.

"I've made that a very clear objective for the new Minister Leon Bignell.

"We're in regular communication with international cycling officials. We've had the Agent-General in London that's met with them."

Gaudry also says she will push for more major cycling events in Australia in all cycling disciplines, including road, track and mountain bike races.

But she says South Australia is unlikely to get an equivalent race if the Tour Down Under does move interstate.

"For Australia and the Oceania region to consider hosting more than one ProTour event would be a big ask," she said.

"What I'm not saying is that the Tour Down Under needs to go somewhere else. What I'm saying is, at this point, it would be a big ask for this region to consider hosting two of that scale.

"There is ripe opportunity to have UCI events at different levels, category two events and continental-level events, that can compliment a ProTour event such as the Tour Down Under."