The "Gossip Girl" star revealed her latest collaboration to MTV News before performing at the new American Eagle store in Times Square on Tuesday night, where she sang a medley of cuts off her yet-untitled album, including a remix of the [artist id="2402281"]Cobra Starship[/artist] track.

"I met [Wayne] a few months ago, and he's honestly — I don't even know if he'll want people to know that he's incredibly polite and respectful," she said about the hip-hop wunderkind, with whom she actually presented the award for Best Song From a Movie at the 2009 MTV Movie Awards. "He's so talented and very funny. And really optimistic, and super supportive of me, which I've really, really appreciated so much."

It seems that since their meeting a few months back, Wayne's been a fan of Blair Waldorf's budding discography — and even picked which track he'd be featured on. "I sent him a couple of my songs," she said. "He's been diggin' on them for a while. Then he heard ['Make It Rain'], and he was like, 'All right, I'm gonna kill it!' "

While many musical partnerships can be conducted without both artists being in the studio together, Meester and Weezy got some face time during the song's recording — a feat for any artist, considering Wayne's notorious nocturnal office hours.

"It was like, literally, 4 o'clock in the morning," Meester said of the time she showed up at the studio to watch Wayne work himself into her song. "He was so sick — he didn't even write anything down. He just, like, vibed to the music and dances. I don't even know how he does it; he's amazing."