Giants instant replay: To call this the best game of rookie David Wilson’s career is a huge understatement.

Turning point

The Giants led, 42-27, but Drew Brees had marched the Saints to the Giants’ 31 when he tried to find tight end Jimmy Graham over the middle. Instead, safety Stevie Brown stepped in front at the 8-yard line and returned the interception 70 yards with 11:50 left to play.

Star of the game

To call this the best game of rookie David Wilson’s career is a huge understatement. The running back accounted for three touchdowns, rushing for 100 yards and compiling 227 yards in kickoff returns. That included a 52-yard touchdown run and a 97-yard kickoff return.

Coaching decisions

Tom Coughlin unsuccessfully challenged Brees’ 44-yard completion to Joseph Morgan with 12:51 to play in the fourth quarter and the Giants ahead, 42-27, leaving them with just one timeout.

Costly mistakes

Eli Manning misread the third-down coverage on Jerrel Jernigan, and Saints cornerback Elbert Mack stepped in front for a 73-yard interception return to give New Orleans a 7-0 lead with 9:38 left in the first quarter. Manning repeated his mistake in the third quarter when safety Isa Abdul-Quddus stepped in front of TE Martellus Bennett at the Saints’ 20, though he was held to a 12-yard return.

Eye-catching

In addition to Wilson’s kickoff returns, Jernigan had a 60-yard return in the third quarter. Overall, the Giants have 1,381 yards in kickoff returns this season, breaking the franchise record set in 2009. … Giants CB Corey Webster used his fingertips to bat away a sure touchdown bomb from Brees to Devery Henderson late in the first quarter.

Injuries

Ahmad Bradshaw went to the locker room midway through the first quarter with a knee issue, but returned in the second quarter. … Cornerback Prince Amukamara left in the fourth quarter with a hamstring issue.

Looking ahead

The Giants (8-5), in a stretch of three of four on the road, are at Atlanta 1 p.m. Sunday, with the Falcons (11-2) coming off a 30-20 loss at Carolina.