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The magnitude of the effect is small, and the clinical relevance is uncertain. I agree. It may cause a mild effect in some people, but overall the effects are small and unlikely to make a major difference Bottom Line: There have been many studies conducted on Garcinia Cambogia in overweight individuals. Some of them show a small amount of weight loss, while other studies show no effect. Garcinia Cambogia Appears to be Very Safe Bottle With Blue Pills It is important to keep in mind that these studies usually only report averages.