DiscoTope 2.0 Server

DiscoTope server predicts discontinuous B cell epitopes from protein
three dimensional structures. The method utilizes calculation of surface
accessibility (estimated in terms of contact numbers) and a novel epitope
propensity amino acid score. The final scores are calculated by combining
the propensity scores of residues in spatial proximity and the contact
numbers.

New in the DiscoTope version 2.0: Novel definition of the spatial neighborhood
used to sum propensity scores and half-sphere exposure as a surface measure.

Note:
The DiscoTope server has been up-dated to improve the user-friendliness.
The server now predicts epitopes in complexes of multiple chains. Also, DiscoTope
output files are now easily downloaded and imported in spreadsheets. Futhermore,
we have facilitated the visualization of prediction results.

PORTABLE VERSION

Would you prefer to run DiscoTope at your own site? The DiscoTope 2.0
software package is in preparation; in the meanwhile an earlier version
(1.1) is available as a stand-alone software package, with the same
functionality as the
DiscoTope 1.1 server online.
Ready-to-ship packages exist for the most common UNIX platforms. There
is a
download page
for academic users; other users are requested to contact CBS Software Package
Manager at software@cbs.dtu.dk.

GETTING HELP

Scientific problems:
Technical problems:

This file was last modified Wednesday 12th 2013f June 2013 09:19:10 GMT