Dr. Chan has over 25 years of experience as an orthopedic surgeon, inventor, researcher and entrepreneur. He has brought a number of innovations from concept to the standard of surgical care, including a vacuum mixing system for total joint replacements and a suture passer for arthroscopic surgery. He is currently an Adjunct Professor at the National University of Singapore (NUS), with appointments at the Department of Orthopaedic Surgery and the Division of Bioengineering, a Fellow of the American Academy of Orthopedic Surgeons and a Fellow of the Canadian Academy of Sport Medicine. His previous experience as the Director of Technology Transfer Office and as the Senior Director of NUS Enterprise at the National University of Singapore provide Dr. Chan with unique executive and management skills. He is currently on the governing board of the Mechanobiology Research Center of Excellence, Singapore. He teaches a course on Bioengineering Design for the third-year Bioengineering students at NUS. He holds a Master’s Degree of Applied Science in Aerospace Engineering from the University of Toronto, a Doctor of Medicine degree from the University of Toronto, completed orthopedic surgery training at the University of Toronto Residency Program and completed a spine fellowship under Dr Ian MacNab. His research interests lie in the area of tissue engineering and the effects of nanotexture on stem cell differentiations. He has been published in over 50 peer-reviewed publications and he currently holds 39 issued U.S. patents, with more patents pending.
Google Scholar Profile at http://goo.gl/r9GsC

Protection of Human Myocardium by Bone Marrow Cells: Role of Long-Term Administration of the Mitochondrial K(ATP) Channel Opener Nicorandil.

Vien Khach Lai , Manuel Galiñanes

ABSTRACTWe have previously demonstrated that bone marrow cells (BMCs) afford myocardial protection as potent as ischemic preconditioning (IP) and also that the myocardium of patients treated with the mitoK(ATP) channel opener nicorandil cannot be protected by IP. Here, we investigated whether nicorandil influences the cardioprotection elicited by BMCs and whether any loss in protection can be rescued by naïve allogenic BMCs.