When asked if he anticipates Abram will be out for the year, Gruden said, "Yes I do."

Abram could have been eligible to return to play in November if he was placed on IR with the designation to return in eight weeks, but it appears the Raiders are eschewing that option in favor of preserving Abram's health and possibly saving that designation for another player.

Abram posted a couple tweets Wednesday morning that shed light on his mindset after sustaining a season-ending injury in the first game of his NFL career.

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Reports of a potential serious shoulder injury for Abram began Tuesday.

It's still not clear when Abram suffered the injury during the Raiders' season-opening win over the Broncos. He was also involved in a hit that required cornerback Gareon Conley to be carted off the field. Gruden said Conley was already back on the practice field Tuesday after the scary incident.

With Abrams sidelined, the Raiders will likely turn to veteran Curtis Riley in the starting lineup along with Karl Joseph, with Erik Harris and Dallin Leavitt in reserve. Harris played exclusively on special teams against Denver and Leavitt was inactive. Lamarcus Joyner, whose role is primarily as a slot corner, can also play deep safety alongside Joseph, although the Raiders prefer him in the slot.