Specifications

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Biological activity

Activity measured by its ability to inhibit the MCSF-induced proliferation of NFS-60 mouse myelogenous leukemia lymphoblast cells.
The ED50 for this effect is typically 1.5-8.7 pg/ml in the presence of 1 ng/ml of rhMCSF.

Preparation and Storage

This product is an active protein and may elicit a biological response in vivo, handle with caution.

Reconstitution

It is recommended to reconstitute ab155619 in sterile PBS to a final concentration of 100 µg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage. Avoid vigorous shaking or vortexing.

General Info

Alternative names

C FMS

CD 115

CD115

CD115 antigen

CFMS

Colony stimulating factor 1 receptor

Colony stimulating factor I receptor

CSF 1 R

CSF 1R

CSF-1 receptor

CSF-1-R

CSF1 R

CSF1R

CSF1R_HUMAN

CSFR

EC 2.7.10.1

FIM 2

FIM2

FMS

FMS proto oncogene

FMS protooncogene

HDLS

M-CSF Receptor

M-CSF-R

Macrophage colony stimulating factor 1 receptor

Macrophage colony stimulating factor I receptor

Macrophage colony-stimulating factor 1 receptor

McDonough feline sarcoma viral (v fms) oncogene homolog

MCSFR

Oncogen FMS

Proto-oncogene c-Fms

V-FMS McDonough feline sarcoma viral oncogen homolog, formerly

see all

Function

Protein tyrosine-kinase transmembrane receptor for CSF1 and IL34.

Tissue specificity

Expressed in bone marrow and in differentiated blood mononuclear cells.