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The 49ers have allowed a franchise record 2,468 rushing yards in 2016 with two games left to play.

The abysmal performance from the San Francisco defense has topped the previous record of 2,363 from the 1978 49ers. San Francisco has held just three of 14 opponents under 100 rushing yards, and their 176.3 rushing yards allowed per game is more than 20 yards per game worse than the 31st-ranked run defense in the NFL. Los Angeles' Todd Gurley and Seattle's Thomas Rawls will take aim at the 49ers defense to close out the regular season. The 49ers D/ST will remain off the fantasy radar, even against Rams QB Jared Goff in Week 16. Wed, Dec 21, 2016 03:11:00 PM

The 49ers are tied for 19th among NFL defenses with seven interceptions this season, but all seven have come from safeties and linebackers. While San Francisco's horrific run defense has shown signs of life in recent weeks, their secondary has been exposed, allowing 299.7 passing yards per game in the last three weeks. Even in a matchup against Chicago backup QB Matt Barkley, the 49ers D/ST is a gamble as a streaming option in fantasy leagues this week. Sat, Dec 3, 2016 01:39:00 PM

San Francisco DE Arik Armstead (shoulder) was placed on injured reserve.

Coach Chip Kelly tabbed DE Quinton Dial as a potential replacement and the team claimed DT Chris Jones off waivers to help fill the void left by Armstead. The San Francisco defense is now further depleted and will continue to be crushed by opposing offenses. The 49ers D/ST is nowhere remotely close to the fantasy radar in Week 10 at Arizona, where RB David Johnson is set to erupt. Wed, Nov 9, 2016 03:53:00 PM

The 49ers are on track to allow 2,789 rushing yards this season, which would be the most since the Houston Oilers gave up 2,814 in 1985.

The San Francisco defense has been absolutely shredded since pitching a Week 1 shutout, allowing 37.0 points and 196.4 rushing yards per game during a current five-game losing skid. Week 6 was especially rough for the 49ers' defense, as they coughed up 313 rushing yards to the Buffalo Bills in a 45-16 blowout loss, allowing 7.1 yards per carry along the way. The 49ers D/ST is not worth fantasy consideration in Week 7 and will not be startable anytime in the near future, as a brutal schedule awaits after a Week 8 bye. Fri, Oct 21, 2016 10:38:00 AM

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The 49ers are tied for 19th among NFL defenses with seven interceptions this season, but all seven have come from safeties and linebackers. While San Francisco's horrific run defense has shown signs of life in recent weeks, their secondary has been exposed, allowing 299.7 passing yards per game in the last three weeks. Even in a matchup against Chicago backup QB Matt Barkley, the 49ers D/ST is a gamble as a streaming option in fantasy leagues this week.

San Francisco DE Arik Armstead (shoulder) was placed on injured reserve.

Coach Chip Kelly tabbed DE Quinton Dial as a potential replacement and the team claimed DT Chris Jones off waivers to help fill the void left by Armstead. The San Francisco defense is now further depleted and will continue to be crushed by opposing offenses. The 49ers D/ST is nowhere remotely close to the fantasy radar in Week 10 at Arizona, where RB David Johnson is set to erupt.

The 49ers are on track to allow 2,789 rushing yards this season, which would be the most since the Houston Oilers gave up 2,814 in 1985.

The San Francisco defense has been absolutely shredded since pitching a Week 1 shutout, allowing 37.0 points and 196.4 rushing yards per game during a current five-game losing skid. Week 6 was especially rough for the 49ers' defense, as they coughed up 313 rushing yards to the Buffalo Bills in a 45-16 blowout loss, allowing 7.1 yards per carry along the way. The 49ers D/ST is not worth fantasy consideration in Week 7 and will not be startable anytime in the near future, as a brutal schedule awaits after a Week 8 bye.

The switch immediately provides a boost to the San Francisco defense that has allowed 35.7 points per game since pitching a Week 1 shutout. While the 49ers will still have trouble with RB David Johnson, Stanton's tendency to turn the ball over (18 career INT to 12 career TD) makes the 49ers D/ST an interesting streaming target for fantasy owners in Week 5.

The San Francisco defense has forced six turnovers through two weeks of the 2016 season.

The 49ers saw two drastically different results in the opening weeks of the season, but their defense has been successful in taking the ball away from opponents. "We want our guys to play fearless," DC Jim O’Neil said. "We don’t want our guys to play scared." San Francisco will need to win the turnover battle in Week 3 to have a shot at a victory in Seattle, where the 49ers D/ST will not be a recommended fantasy option.

The San Francisco 49ers have forced just 12 turnovers in 15 games this season.

The 49ers check-in at 31st among NFL defenses in takeaways, ahead of only the Dallas Cowboys. San Francisco failed to force a turnover in three of the last six weeks, and the team went 1-5 in that stretch. Week 17 brings a matchup with the St. Louis Rams, where the 28th-ranked run defense of the 49ers will be no match for Todd Gurley. Fantasy owners will be wise to leave the 49ers D/ST on the waiver wire.

McCarron racked up 280 passing yards and threw a pair of touchdowns after Dalton went down in Week 14. The backup quarterback also chucked a pair of interceptions as he showed no apprehension about throwing the ball deep. The 49ers D/ST has been such a disappointment in 2015, they are not a recommended fantasy option against a quarterback with 36 career passing attempts. Leave this group on the waiver wire.

The San Francisco defense will face Cleveland QB Johnny Manziel in Week 14.

Manziel is back as the Cleveland starter this week, and last played in Week 10 when he threw for 372 yards. Manziel has thrown only two interceptions in 128 passing attempts this season, but is completing under 60 percent of his passes on the year. Despite a relatively friendly matchup, the 49ers D/ST is not a recommended fantasy option in Week 14, as the group has recorded just nine turnovers and 20 sacks in 12 games.

The San Francisco defense has forced just eight turnovers in 11 games, the second-worst mark among NFL defenses.

The 49ers have not recorded an interception since Week 7, in what has been a rough season for coach Jim Tomsula's defense. In addition to not forcing turnovers, the San Francisco defense is allowing opposing quarterbacks to complete passes at a 69.1 percent clip, the second-highest percentage in the NFL. The 49ers D/ST is an avoidable group this week at Chicago.

San Francisco LB Ahmad Brooks is going through the NFL concussion protocol this week and did not practice on Thursday.

Brooks had three tackles and a sack in Week 11 at Seattle, but is a dicey bet to suit up in Week 12 when the 49ers host the Arizona Cardinals. With or without Brooks, the San Francisco defense will face a stiff challenge this week against the Arizona offense that has averaged a hefty 35.7 points per game over the last three weeks. The 49ers D/ST can be left comfortably on the waiver wire.

The San Francisco defense will attempt to improve upon their Week 7 performance against the Seahawks when the team travels to Seattle in Week 11.

The first 2015 matchup between Seattle and San Francisco was lopsided as Russell Wilson and company tallied 388 total yards in a 20-3 victory at Levi's Stadium. This week, San Francisco will look to return the favor at CenturyLink Field in Seattle. Despite a surprising Week 10 effort against Atlanta, the San Francisco defense is struggling against opposing passing games and has failed to make a dent in the sack and turnover categories this season. The 49ers D/ST won't be a viable fantasy option on the road in Week 11.

The San Francisco defense heads into their Week 10 bye in the bottom-five among NFL defenses in passing yards allowed per game, completion percentage, and yards per attempt from opposing passers.

The 49ers D/ST has not even sniffed the fantasy radar this season and their struggles against the pass will keep them on fantasy waiver wires throughout the remainder of 2015. After the bye, San Francisco takes on Seattle and Arizona, and will not be a recommended fantasy option.

The San Francisco defense has a tough Week 9 matchup on tap as the Atlanta Falcons travel to Levi's Stadium to face the 49ers.

Atlanta is fourth among NFL offenses, averaging a healthy 414.8 total yards per game in 2015. With the San Francisco offense being led by Blaine Gabbert this week, the 49ers defense will likely be on the field a ton while having to deal with Devonta Freeman and Julio Jones. The 49ers D/ST has been a miserable fantasy option in 2015 and won't be startable in Week 9.

The San Francisco defense will face a tough task in Week 8 as they look to corral St. Louis running back Todd Gurley.

Gurley has been an absolute beast as a rookie and has run for 144.3 yards per game over the last three weeks. The 49ers' 20th-ranked run defense will likely have a difficult time stopping Gurley, making the San Francisco D/ST an avoidable Week 8 fantasy option. This group will remain on fantasy waiver wires for the foreseeable future with matchups against Atlanta, Seattle, and Arizona looming after St. Louis.