• extensive and early inflammation is observed compared with control wild-type Tnfrsf9, Fas lpr homozygotes

• by 3 months, extensive mononuclear cell infiltration is observed, becoming intense by 5 months while controls show no infiltrate at 1 month, mimimal inflammatory lesions at 3 months and extensive, although less severe than double mutants, infiltrates by 5 months of age

• extensive and early inflammation is observed compared with control wild-type Tnfrsf9, Fas lpr homozygotes

• by 3 months, extensive mononuclear cell infiltration is observed, becoming intense by 5 months while controls show no infiltrate at 1 month, mimimal inflammatory lesions at 3 months and extensive, although less severe than double mutants, infiltrates by 5 months of age

• extensive and early inflammation is observed compared with control wild-type Tnfrsf9, Fas lpr homozygotes

• by 3 months, extensive mononuclear cell infiltration is observed, becoming intense by 5 months while controls show no infiltrate at 1 month, mimimal inflammatory lesions at 3 months and extensive, although less severe than double mutants, infiltrates by 5 months of age