When they say "don't let the bed bugs bite" in Baltimore, they mean it.

Pest control company Orkin released its list of Top 50 Bed Bugs Cities, and the Charm City came in at No. 1 -- a jump of nine spots from the previous year. The list is based on treatment data from the metro areas where Orkin performed the most bed bug treatments from December 1, 2015, to November 30, 2016.

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Baltimore's neighbor Washington D.C. came in at No. 2, with last year's No. 1, Chicago, New York and Columbus, Ohio, rounding out the top 5. See below for the full list.

“We have more people affected by bed bugs in the United States now than ever before,” Orkin Entomologist and Director of Technical Services Ron Harrison said in a release. “They were virtually unheard of in the U.S. 10 years ago."

The bugs are resilient, able to survive in all manner of environments, and can travel with ease.

“Anyone can get bed bugs in their home," Harrison said. "They are not a sign of uncleanliness. Bed bugs only need blood to survive. We have treated for bed bugs in everything from million dollar homes to public housing."

“People may have bed bugs and not know it, because many people have no physical reaction to bed bug bites,” Harrison said. “That’s why it’s important for people everywhere to inspect for bed bugs regularly.”