RNA Modeling

In article <Pine.BSI.3.91.950315122433.12136A-100000 at nudge.io.org>,
Noe Zamel <noe at io.org> wrote:
>Hi.
>>Does anyone have any good tips on using computer programs for modelling
>RNA
>instead of building physical models? We have Biosym's Insight/Discover.
>
There was some nice work reported a few years ago on a very
general and apparently useful constraint-satisfaction system
that combines various molecular dynamics/energy-minimization
methods with other (heuristic, user-defined, pattern-based)
sources of information. I know they had (have) a working system,
but I don't know whether they made their code available.
The authors were at l'Universite' de Montreal (and perhaps
also McGill or UQAM), as I recall -- sorry, I don't have the
paper handy to give more details. But here's a ref:
@article{Major-et-al-91,
author = "F. Major
and M. Turcotte
and D. Gautheret
and G. Lapalme
and E. Fillion
and R. Cedergren",
title = "The combination of symbolic and numerical computation
for three-dimensional modeling of {RNA}",
journal = "Science",
volume = "253",
pages = "1255-1260",
year = "1991"}
-- Evan
Evan W. Steeg (416) 978-5182 steeg at ai.toronto.edu
Dept of Computer Science steeg at t13.lanl.gov
University of Toronto,
Toronto, Canada M5S 1A4 FAX: (416) 978-1455
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