Some weekends it seems like nothing much is happening. This will not be one of those.

The Bay Area is gearing up for a remarkable confluence of sports, music and culture — a perfect storm of high-profile events where literally there is something for everyone.

Baseball playoffs. Bluegrass. Football. Justin Bieber onstage. America’s Cup World Series regatta on the bay. And the breathtaking sight of the Blue Angels in the sky.

And that’s just the start of a lengthy list of pulse-racing doings that will have the region hopping, dancing and cheering.

“This is what we live for here,” said Giants CEO Larry Baer. “There’s just a vibe to the region right now. There’s so many events going on and it makes you feel alive. We’re lucky to live in such a vibrant community.”

That’s not just Chamber of Commerce-style hype, either. Consider this marquee lineup:

The Giants open the National League postseason with games Saturday and Sunday at AT&T Park. The surprising A’s will start their American League playoff run on the road before returning to O.co Coliseum next week. Meanwhile, the 49ers are playing at Candlestick Park on Sunday while Stanford and Cal both have home football games Saturday.

Teen heartthrob Bieber plays Oracle Arena in Oakland on Saturday, and Madonna is at HP Pavilion in San Jose both Saturday and Sunday. Indie rock band Florence and the Machine performs at the Shoreline Amphitheatre in Mountain View on Friday.

The annual Fleet Week celebration, highlighted by the Blue Angels flying team, is expected to draw 300,000 visitors a day to the San Francisco waterfront. There’s also the three-day Hardly Strictly Bluegrass festival at Golden Gate Park as well as the Italian Heritage Parade in North Beach and the Castro Street Fair on Sunday. Runners will fill South Bay streets Sunday morning at the Rock ‘n’ Roll San Jose Half Marathon.

“That’s pretty awesome,” said Jonny Gomes, the A’s outfielder and Petaluma native, about the weekend. “You should go around town, soak in all that stuff, then head for Napa and do some wine tasting on your way out.”

So, buckle up. Wait, on second thought, officials are asking — actually, begging — that you instead use public transportation because this convergence of events promises to create traffic headaches.

“This really is unprecedented,” said Jerry Robbins of the San Francisco Municipal Transportation Agency. “We’ve had football and baseball simultaneously. We’ve had football and Fleet Week simultaneously. But we’ve never had everything all at once. We’re encouraging people to use any transportation other than drive.”

Public officials have had this weekend circled for months and are beefing up mass transit service to help deal with the masses, like the wave heading for the free Hardly Strictly Bluegrass event. The six-stage, 88-act jam includes an eclectic range of artists such as Emmylou Harris, The Civil Wars, Elvis Costello and Dwight Yoakam.

The festival reportedly has drawn 800,000 in the past, but publicist Tracey Buck would only say that they are expecting a “massive” crowd.

“This is probably the craziest weekend in a good long time and maybe the craziest ever,” Buck said. “When it rains, it pours.” Then she stopped herself. “But hopefully there’s no rain.”

No worry. The National Weather Service is predicting a pleasant fall weekend in the Bay Area after the recent warm spell.

In addition to events that had been long scheduled, the Giants and the A’s crashed the party by surging into the playoffs — making it a great time to be a Bay Area sports fan.

The Giants are vying for their second World Series title in three years. The A’s, despite one of the lowest payrolls in baseball, have become the national pastime’s best story. The 49ers are playing like a Super Bowl contender.

“It’s a perfect weekend for sports,” said Gary Radnich, the longtime KRON television and KNBR radio personality.

So perfect that he’s staying home to watch multiple games from his couch.

Music fans also might feel there is too much going on. Gary Bongiovanni, editor-in-chief of Pollstar, which monitors the concert scene, said it’s only coincidence that so many must-see acts have arrived at one time in the Bay Area.

But while tickets for the Madonna show and others might have been purchased months ago, Bongiovanni said: “Your baby-sitter bills might be a little high this weekend.”

Mike Ferguson, spokesman with the San Francisco area office of the California Highway Patrol, said if people must drive, they should carpool and give themselves plenty of extra time.

“We don’t want to discourage you from coming out,” he said. “But be smart about it. If you’re going to Fleet Week, come early because if you’re traveling near 49ers game time, you’re going to be facing trouble.”

49ers owner Jed York and wife Danielle plan to attend a rooftop barbecue Saturday to watch the Blue Angels and, of course, the 49ers game at Candlestick Park. But that’s enough fun, he said, with Danielle expecting their first child in two weeks.

“This is just a great time with all the teams playing and everything going on,” York said. “A rising tide really does float all boats. It’s really exciting. In fact I told Larry Baer that it’s a 50 percent chance that Danielle goes into labor either at a Niners or Giants game.”