The 2010 Business Network / Trustees Symposium will explore the manner in which regulatory systems are ubiquitous in the world around us, including in physical, biological, and social systems. While many of these are very different from the top-down, government imposed notion of regulation commonly thought of when we hear the word "regulation", we feel there is a great deal to learn from a truly comparative, trans-disciplinary approach to this problem. We are proceeding on the assumption there may be important common lessons, concepts and methods to be inferred about the stability and predictability (or lack thereof) of dynamics in a wide range of systems ranging from developmental biology, through to population levels, and cultural institutions, when subjected to different forms of regulatory mechanism. Topics to be covered include Regulation in Biological Systems, Regulation of the Economy, Regulation of Communications Systems and the Internet, Regulation of Health Care and Biomedicine, Regulation of the Atmosphere and Space, and Regulation of International Affairs.