PM-120Genetic Analysis I

This module is designed to develop the skills required for students of genetics and medical genetics.
Students will meet with tutors and be given a series of assignments designed to develop skills in key areas such as essay writing, presentations and general numeracy.
Joint sessions will cover generic skills such as internet searching for scientific sources, referencing and plagiarism.

PM-127Energy and Metabolism: The Reactions of Life

This module begins with an introduction to enzymology, enzyme kinetics and enzyme regulation. Next there is an introduction to bioenergetics and a discussion of the central metabolic pathways by which energy from food is used to fuel the synthesis of the energy currency molecule ATP (with particular attention to glycolysis, the citric acid cycle, ß oxidation of fatty acids, and oxidative phosphorylation). The concept of tissue and organ specificity is introduced, and finally the role of the hormones insulin, glucagon, epinephrine, growth hormone, thyroid hormone and leptin in controlling these pathways and producing effects on the body is considered.

PM-130Biochemistry Skills Development

This module is designed to develop the skills required for students of biochemistry and medical biochemistry. Students meet with their tutors and will be given a series of assignments designed to develop skills in key areas such as essay writing, presentations and general numeracy.
Joint session cover generic skills such as internet searching for scientific sources, referencing and plagiarism

PM-243Clinical Biochemistry & Physiology

The module begins with a discussion of selected metabolic disorders of carbohydrate metabolism and their pathological consequences with particular emphasis on diabetes mellitus. The molecular mechanisms underlying polycystic ovarian syndrome are then considered. This is followed by a consideration of the biochemical basis of haemostasis and blood clot lysis. Next there is a discussion of inborn errors of metabolism, and the biochemical pathways affected. Finally the module reviews mechanisms of protein transport and their relevance to storage diseases.

PM-253Techniques in Molecular Biology

The module will provide a sound theoretical and practical basis to a comprehensive range of biomolecular techniques currently employed in molecular genetics and biochemistry. Particular emphasis is placed on DNA recombinant technology, next generation sequencing, transcriptomics, proteomics and mass spectrometry.

PM-304Biomolecular Research Project

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PM-319Membranes and Energy Transduction

The module provides an understanding of the dynamic structure and properties of biological membranes and the nature of lipid-lipid and lipid-protein interactions. An appreciation of the molecular architecture of energy-conserving membranes is also provided together with an understanding of the molecular mechanisms involved in energy transduction.

PM-331Membrane Trafficking

The module provides an understanding of the subcellular organelles, the regulation of their biosynthesis and how
impairment of this process leads to disease.

PM-334Biochemistry Literature Review and Communication

Students will acquire a detailed knowledge of one topical research area of key importance to their particular degree scheme.