A 62-year-old female presented with worsening back pain. Histologic examination of endoscopic biopsies of duodental lesions identified a fragment of duodenal tissue with a diffuse infiltrate of neoplastic cells with positive staining for anti-CD138, consistent with plasmacytoma.

Computerized tomography angiogram (CTA) identified a foreign body in the proximal sigmoid colon of a 71-year-old man with adjacent inflammatory changes, with structural characteristics suggesting a chicken gracile bone, which was removed on colonoscopy.

Tracheoesophageal fistulas often present clinically as increased secretions, coughing with or without hypoxia after swallowing, and recurrent aspiration pneumonia. We describe a tracheoesophageal fistula that was closed with use of an over-the-scope Aponos clip.

PEG tube placement is a safe procedure with minor complications such as site infection and irritation. We present a rare case of intra-abdominal bleeding secondary to catastrophic splenic injury 12 hours after PEG tube placement resulting in hemodynamic compromise.

We present the use of a novel thrombopoietin receptor agonist, eltrombopag, to sustain platelet levels for the safe and complete endoscopic submucosal dissection of a gastric carcinoid in a patient with severe thrombocytopenia.