Background*

Mr. Ian T. Clark serves as Director At Large at Biotechnology Industry Organization. Mr. Clark served as Chief Executive Officer of Genentech at Roche Holding AG and served as its Head of Global Product Strategy since January 2010. He served as Senior Vice President of commercial operations at Genentech, Inc., from August 2005 to December 2005 and its Executive Vice President of Commercial Operations since December 2005; General Manager of BioOncology; Senior Vice President ... of BioOncology; Executive Vice President of Global Marketing; Head of Global Product Strategy and Chief Marketing Officer. Prior to joining Genentech, he served as president, Novartis Canada from 2001 to 2003. He served as Chief Operating Officer for Novartis United Kingdom from 1999 to 2001. Prior to joining Novartis in 1999, he served in positions of increasing strategic importance in sales, marketing and business development at Ivax Pharma and Sanofi- Synthelabo in the United Kingdom. He started his career at Pharmacia, holding positions in both sales and marketing. He serves as Member of Economic Advisory Council at Federal Reserve Bank of San Francisco. He has been a Director of InterMune, Inc. since September 29, 2014. Mr. Clark serves as a Member of Executive Council at TechNet. He has been an Independent Director of Solazyme, Inc. since April 2011. He serves as a Director of Genentech, Inc. He served as a Director of Dendreon Corp. from October 12, 2009 to September 2010. He served as Non Executive Director of Vernalis plc from January 1, 2007 to December 31, 2009. He was selected as the San Francisco Business Times 2012 Most Admired Chief Executive Officer in the Public Companies category. He received a BS in biological sciences from Southampton University in the United Kingdom.

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