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Human G Protein-Coupled Receptor 85 (GPR85) Interaktionspartner

Risk-associated variants in GPR85 are associated with phenotypes similar to those found in patients with schizophrenia.

The areas expressing high levels of SREB2 mRNA overlap with brain structures known to possess high levels of plasticity, namely, the hippocampal formation, olfactory system, and supraoptic and paraventricular nuclei.

GPR85 Antigen-Profil

Protein Überblick

Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins (Matsumoto et al., 2000