Summary

When transplanted into the anterior chamber of the guinea pig eye, an unusual brain tumor displayed invasion and destructiveness to the structure of the eye. It also led to a dispersion of the melanin of the iris. Large amounts of melanin were phagocytosed by the transplanted tumor cells.

In an attempt to classify this tumor, a neuroectodermal growth or a melanomatosis of the meninges could be ruled out. Morphologic alterations of the tumor in the transplants were interpreted as being consistent with a tumor originating from reticuloendothelial elements.