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Show notes:
The BEST resource for all things intranasal is the intranasal.net website. It has tons of current evidence based literature, dosages, guidelines, and example protocols. I highly recommend it; I used this site extensively when developing our own hospital’s protocols.
Safety of intranasal fentanyl:
Intranasal Fentanyul Reduces Acute Pain in Children in the Emergency Department- A safety and Efficacy Study
Use of Intranasal Fentanyl for the Relief of Pediatric Orthopedic Trauma Pain
Intranasal Fentanyl for Pain Control: Current Status with a Focus on Patient Considerations
Hypothesized Route for Nose-Brain Pathway, Bypassing the Blood Brain Barrier:
From Nose to Brain: Understanding Transport Capacity and Transport Rate of Drugs
Is Nose-to-Brain Transport of Drugs In Man A Reality?
Procedural Sedation:
Plasma Concentrations of Flumazenil Following Intranasal Administration In Children
Efficacy of Intranasal Naloxone as a Needleless Alternative for Treatment of Opioid Overdose in the Prehospital Setting
Comparison of Intravenous and Intranasal Sufentanil Absorption and Sedation
Seizure Control:
Comparison of Intranasal Midazolam With Intravenous Diazepam for Treating Febrile Seizures in Children: Prospective, Randomized Study

Show notes:
The BEST resource for all things intranasal is the intranasal.net website. It has tons of current evidence based literature, dosages, guidelines, and example protocols. I highly recommend it; I used this site extensively when developing our own hospital’s protocols.
Safety of intranasal fentanyl:
Intranasal Fentanyul Reduces Acute Pain in Children in the Emergency Department- A safety and Efficacy Study
Use of Intranasal Fentanyl for the Relief of Pediatric Orthopedic Trauma Pain
Intranasal Fentanyl for Pain Control: Current Status with a Focus on Patient Considerations
Hypothesized Route for Nose-Brain Pathway, Bypassing the Blood Brain Barrier:
From Nose to Brain: Understanding Transport Capacity and Transport Rate of Drugs
Is Nose-to-Brain Transport of Drugs In Man A Reality?
Procedural Sedation:
Plasma Concentrations of Flumazenil Following Intranasal Administration In Children
Efficacy of Intranasal Naloxone as a Needleless Alternative for Treatment of Opioid Overdose in the Prehospital Setting
Comparison of Intravenous and Intranasal Sufentanil Absorption and Sedation
Seizure Control:
Comparison of Intranasal Midazolam With Intravenous Diazepam for Treating Febrile Seizures in Children: Prospective, Randomized StudyRead less

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