Use of corticosteroid is not associated with improved outcomes in idiopathic pulmonary fibrosis (IPF) patients admitted to the hospital with acute exacerbation (AE), reveals a recent study. In addition, corticosteroids may even contribute to reduced overall survival following exacerbation.

Acne is a common skin problem seen in primary care. Dr Wong
Soon Tee of Assurance Skin Clinic at Mt Elizabeth Novena Hospital, Singapore
shares his insights with Pearl Toh on how to manage acne in the primary care
setting.

However, edoxaban, at high doses, demonstrated better safety than warfarin. Major bleeding occurred significantly less frequently in the former treatment arm than in the latter, both in patients with (3.20 percent vs 4.07 percent per year; HR, 0.79, 95 percent CI, 0.65–0.96) and without (2.68 percent vs 3.30 percent; HR, 0.81, 95 percent CI, 0.69–0.96) diabetes.

Stratification according to the use of insulin did not meaningfully alter the findings, and the effects of a low-dose edoxaban regimen did not appear to be modified by diabetes status.

“Since patients with insulin treated diabetes and AF are at higher risk for both stroke and bleeding, use of safer, yet effective, oral anticoagulants, such as edoxaban, may be preferred over [vitamin K antagonists],” said the researchers.

Use of corticosteroid is not associated with improved outcomes in idiopathic pulmonary fibrosis (IPF) patients admitted to the hospital with acute exacerbation (AE), reveals a recent study. In addition, corticosteroids may even contribute to reduced overall survival following exacerbation.

Acne is a common skin problem seen in primary care. Dr Wong
Soon Tee of Assurance Skin Clinic at Mt Elizabeth Novena Hospital, Singapore
shares his insights with Pearl Toh on how to manage acne in the primary care
setting.