MATERIALS AND METHODS: Glass and titanium disks were coated with a superhydrophobic coating, consisting of two different coatings (micro-and nanostructured coating and a low surface energy coating), as well as just these two coatings. Modification of the coating with polydimethylsiloxane (PDMS) was also done in order to enhance itsmechanical properties for coating softer materials. Cell response was tested by 1. Culturing cells on the surfaces and evaluating their attachment by determining the number cells as well as examining cell morphology2. MTT cell viability assay to evaluate coating toxicity.

RESULTS: Super hydrophobic surfaces displayed considerably reduced cell and bacterial adhesion compared to control samples, as well as the two individual coatings making up the super hydrophobic coating. No evidence of coating toxicity of the original coating or the PDMS modification was observed.

CONCLUSION: Based on these preliminary tests, super hydrophobic coating can be used for coating medical implants in instances where cell and bacterial adhesion is not desired.