UNC sequenced the RNA for 10,000 tumor samples as part of The Cancer Genome Atlas project, a National Cancer Institute and National Human Genome Research Institute-backed effort to create a comprehensive atlas of the genetic changes in cancer.

In preliminary findings presented at the 2016 San Antonio Breast Cancer Symposium, researchers showed that older patients were as likely as younger patients to receive targeted therapy and enroll in therapeutic trials based on their sequencing results.

A UNC Lineberger study published in the journal Breast Cancer Research and Treatment drew upon surveys that assessed health-related quality of life issues for women aged 20 to 74 years who lived in North Carolina and had breast cancer. The analysis was part of the third phase of the Carolina Breast Cancer Study.

Founded with support from KickStart Venture Services, a UNC-Chapel Hill program that works to turn University research into new companies, G1 Therapeutics is developing novel therapeutics based on discoveries at UNC Lineberger Comprehensive Cancer Center.

UNC Lineberger's Seth Noar, PhD, and colleagues report in a new study that anti-tanning bed messages with images showing longer-term health effects, such as skin cancer or wrinkles, produced greater negative emotional reactions and higher ratings of effectiveness in a survey of female college students than text-only messages.

UNC Lineberger's Michael J. Emanuele, PhD, and colleagues have identified a key activator that can turn on FoxM1, a protein that drives expression of genes that help cells replicate and divide, a finding they published in the journal Molecular and Cellular Biology. They also discovered, paradoxically, that the activator for FoxM1 is also responsible for turning this protein off.

Two new faculty members have joined the UNC Lineberger Comprehensive Cancer Center to help launch groundbreaking immunotherapy clinical trials that will test an experimental treatment in which patients’ own immune cells are genetically engineered to fight their cancer.

A symposium co-sponsored by the UNC Lineberger Comprehensive Cancer Center brought leading breast cancer researchers together Friday to share findings about the genetic and environmental factors driving disparities in the disease’s incidence and mortality.

In the Journal of the American Medical Association, a study led by UNC Lineberger member Ronald C. Chen, MD, MPH, examines quality-of-life outcomes for modern treatment choices most patients will face, including active surveillance, radical prostatectomy, external beam radiation treatment, and brachytherapy.