Bleeding disorder. Vwd is the most common inherited bleeding disorder. Von wiilebrand factor is a clotting protein that helps stabilize clots by helping to bind platelets together and also helps carry factor viii in the blood. In vwd, vw factor is either decreased or does not function appropriately. Clots will form but they are not stable, can easily fall apart/ dissolve, and bleeding will then occur.
Read more...

Bleeding disorder. Vwd is a decrease in production (usually) of a specific protein required for clotting blood, called vw factor. The actual amount produced varies, but bleeding is more common, especially after surgeries or accidents. There are treatments for this disorder. This is type 1 and it is the most common bleeding disorder.
Read more...

Not necessarily. "risky" is hard to define. Because menstrual bleeding is one of the more common problems women with VWD have, it is considered "riskier" for women than men. It is very possible to manage menstrual bleeding, as well as bleeding with childbirth very effectively, however. Once that happens, VWD is no riskier for women than it is for men.
Read more...

50% in most cases. an overwhelming majority of von Willebrand Disease (VWD) is dominant, meaning that if you carry one gene, you have VWD. Supposing that your girl friend has one VWD on one chromosone, and the other is normal, the chance of her passing that VWD gene to your offspring would be 50%. Most patients with VWD have type 1 disease which is fully compatible with normal life span.
Read more...

Depends. If your GF has type I and you are in fact unaffected, each child has 50% chance of inheriting. If she has Type III, all children will have Type I, none will have Type III. If she has Type II, most have recessive inheritance also; most likely that all children will be carriers but none will have disease. .
Read more...

More info needed. Some von Willebrand is transmitted genetically and some is acquired by a medication or other factor. What type does your girlfriend have? Her doctor can tell her and then a discussion of potential transmission to offspring can occur.
Read more...

Unique, certainly. These are both fairly commonly inherited disorders. Factor v leiden occurs in about 1/100 people. Von willebrand is also about 1/100 or so. So it is conceivable that this could occur in the same person. There are probably a few like you around.
Read more...

Why? I agree that there are probably others out there with the same combination of problems. And this should not preclude any necessary therapy. If you have bleeding due to your vwd, treatment can be provided without greatly increasing your risk for developing a clot. Conversely, many patients with fv leiden (what i think you mean) don't need to take blood thinners, so VWD shouldn't be a problem.
Read more...

Interesting. Von willebrand disease is a difficult disease to diagnose. The most typical form is type 1, generating low levels of protein. However, your body can make this protein, and usually the treatment is a medication that "stresses" the body, causing release of von willebrand protein.
I have known of several people who have low levels during childhood and the levels normalize later in life.
Read more...

Bleeding disorder. Vwd is the most common inherited bleeding disorder. Von wiilebrand factor is a clotting protein that helps stabilize clots by helping to bind platelets together and also helps carry factor viii in the blood. In vwd, vw factor is either decreased or does not function appropriately. Clots will form but they are not stable, can easily fall apart/ dissolve, and bleeding will then occur.
Read more...

Bleeding disorder. Vwd is a decrease in production (usually) of a specific protein required for clotting blood, called vw factor. The actual amount produced varies, but bleeding is more common, especially after surgeries or accidents. There are treatments for this disorder. This is type 1 and it is the most common bleeding disorder.
Read more...

Not necessarily. "risky" is hard to define. Because menstrual bleeding is one of the more common problems women with VWD have, it is considered "riskier" for women than men. It is very possible to manage menstrual bleeding, as well as bleeding with childbirth very effectively, however. Once that happens, VWD is no riskier for women than it is for men.
Read more...

50% in most cases. an overwhelming majority of von Willebrand Disease (VWD) is dominant, meaning that if you carry one gene, you have VWD. Supposing that your girl friend has one VWD on one chromosone, and the other is normal, the chance of her passing that VWD gene to your offspring would be 50%. Most patients with VWD have type 1 disease which is fully compatible with normal life span.
Read more...

Depends. If your GF has type I and you are in fact unaffected, each child has 50% chance of inheriting. If she has Type III, all children will have Type I, none will have Type III. If she has Type II, most have recessive inheritance also; most likely that all children will be carriers but none will have disease. .
Read more...

More info needed. Some von Willebrand is transmitted genetically and some is acquired by a medication or other factor. What type does your girlfriend have? Her doctor can tell her and then a discussion of potential transmission to offspring can occur.
Read more...

Unique, certainly. These are both fairly commonly inherited disorders. Factor v leiden occurs in about 1/100 people. Von willebrand is also about 1/100 or so. So it is conceivable that this could occur in the same person. There are probably a few like you around.
Read more...

Why? I agree that there are probably others out there with the same combination of problems. And this should not preclude any necessary therapy. If you have bleeding due to your vwd, treatment can be provided without greatly increasing your risk for developing a clot. Conversely, many patients with fv leiden (what i think you mean) don't need to take blood thinners, so VWD shouldn't be a problem.
Read more...

Interesting. Von willebrand disease is a difficult disease to diagnose. The most typical form is type 1, generating low levels of protein. However, your body can make this protein, and usually the treatment is a medication that "stresses" the body, causing release of von willebrand protein.
I have known of several people who have low levels during childhood and the levels normalize later in life.
Read more...