(Carboxy-3-oxopropylamino)-3-propylsilylcellulose as a novel organocatalyst for the synthesis of coumarin derivatives under solvent-free conditions

Department of Chemistry, College of Sciences, University of Birjand, P. O. Box 97175-615, Birjand, Iran

Abstract

In this research, (Carboxy-3-oxopropylamino)-3-propylsilylcellulose (COPAPSC) as an organocatalyst, has been synthesized by grafting of succinic anhydride on the NH2-modified cellulose (cellulose functionalized with 3- aminopropyltriethoxysilane). The –CO2H group-functionalized cellulose (COPAPSC) is used as a catalyst for the synthesis of coumarin derivatives from the reaction of phenolic substrate and β- Keto-esters under solvent-free conditions. The results showed that the yield of products is between 85-94%. The advantages of this reaction include simple work-up, short reaction time, excellent yields as well as easily separation of catalyst. The catalyst can be reused several times in subsequent reactions without any decreasing in the catalyst reactivity.