The NKp46 and NKp46-ligand interaction contributes to NK cell activation.

this study shows that the NKp46-activating receptor recognizes an unknown ligand expressed by human metapneumovirus-infected cells

Intrahepatic NKp46 NK cells exhibited anti-HCV activity via cell-to-cell contact. The variation of the NKp46 proportion in individuals could be attributed to the diversity of HCV resistance observed in these individuals.

this study demonstrates the role of NCR1 in antibody response to mouse cytomegalovirus infection

Our findings uncover a detrimental role of T-bet-dependent NKp46(+) ILCs in the development of CNS autoimmune disease.

The results identify an unexpected phenotypic instability within NKp46(+) ILC3 that suggests a major role for environmental signals in tuning ILC3 functional plasticity.

The authors delineated the fungal ligands to be the Candida glabrata adhesins Epa1, Epa6 (显示 Epha6 抗体), and Epa7 and demonstrated that clearance of systemic Candida glabrata infections in vivo depends on their recognition by mouse NCR1.

it is demonstrated that NCR1 dampens allergic eosinophilic airway inflammation.

this study using Ncr1-deficient mice, shows that NCR1 plays a critical role in controlling human metapneumovirus infection

Rag knockout mice that possess fully functional NKp46(+) cells

Ncr1-Noe proteins accumulate in the endoplasmic reticulum, and that the expression of Ncr1-Noe proteins, but not WT Ncr1, leads to increased Helios (显示 ZNFN1A2 抗体) expression