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Clinical Microbiome

Clinical Microbiome

Take a ‘snapshot’ of the in vivo state right at the moment of collection. Ensure your microbiome profiles represent the phenotype of interest, not artefacts of overgrowth or degradation.

Causal relationships have been established between specific microbiome architectures and diseases such as obesity, IBD, asthma, diabetes, auto-immune diseases and more. A variety of drugs have the potential to modulate the microbiome and the microbiome has shown to be capable of modulating drug degradation and adsorption.

DNA Genotek combines OMNIgene® microbiome collection and stabilization products and GenoFIND™ end-to-end services to facilitate the study of the microbiome during pre-clinical and clinical studies. Examples of applications that can benefit from DNA Genotek’s microbiome products and services for clinical-microbiomics are:

Comparative studies of disease states - discover and evaluate links between microbiome composition and various diseases

Biomarkers for patient segmentation – identify biomarkers that are predictive of treatment outcomes

Monitor effect of drugs on microbiome – new targets for medical intervention

Development of probiotics, prebiotics and microbiome therapeutics

Improving sample quality is the best way to improve data quality. Consider the cell cycle of a human (eukaryotic) cell at 24hrs, and the changes that can impact biomarkers in human tissue between collection and analysis. Now consider that the cell cycle of many microbes is on the order of 40 minutes. Without reliable sample collection and immediate stabilization to ensure accurate representation of the in vivo state, reproducibility and comparability of microbiome profiles between collection sites, or between studies would be next to impossible.

DNA Genotek’s microbiome product line provides an all-in-one system for the non-invasive self collection and immediate stabilization of microbial nucleic acids.

Featured Products for Clinical Microbiome

OMNIgene•GUT | OM-200

DNA Genotek offers GenoFIND™, a complete suite of genomics and microbiome services designed to combine our passion for customer service with industry leading sample collection and stabilization expertise. Whether you are starting a new genomics or microbiome study, translating your research into a commercial business, or expanding your research to include metagenomic analysis, DNA Genotek covers it all.

Full terms and conditions for all DNA Genotek products are available here.

DNA Genotek Inc., a subsidiary of OraSure Technologies, Inc. (NASDAQ: OSUR), focuses on providing high-quality biological sample collection products and end-to-end services for human genomics, microbiome and infectious disease applications. The Company's Oragene•Dx and ORAcollect•Dx product lines are the first and only FDA 510(k) cleared saliva-based DNA collection devices for in vitro diagnostic use. DNA Genotek also offers Research Use Only products to collect and preserve large amounts of DNA or RNA from multiple sample types. DNA Genotek markets its products worldwide and has a global customer base with thousands of customers in over 100 countries.