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Di-methyl (ε-N) Lysine Antibody

Catalog #

Pack Size

Price(USD)

ICP0701

100 μg

$325.00

Quantity:

Product Description

The affinity purified rabbit polyclonal anti-Di-methylated lysine antibodies are developed using a technique unique to ImmuneChem. The Di-methylated lysine antibodies are affinity purified using N-Di-methyl (epsilon amino group) lysine on agarose as the affinity matrix. The antibodies could be utilized for detection, quantization and isolation of proteins with Di-methylated lysine residues.

The antibody is immunoaffinity purified with epsilon N-Di-methyl lysine on agarose.

Specificity

The antibody recognizes proteins or peptides with di-methyl lysine residues. There is no cross reaction with acetylated proteins. The cross reactivity with mono-methyl lysine has not been tested.

Applications

ELISA, WB, IP

Scientific Description

Protein lysine methylation (MeK) is a conserved post-translational modification and is an important biochemical process for many protein-protein interactions. It is found in many proteins, for example calmodulin, cytochrome C, chromosomal proteins, histones, non-histones as well as neural storage body proteins. It has been suggested that di-methylation of lysine plays an important role in gene silencing.[1]

Storage & Stability

Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is three years from date of shipping if stored properly. Do not aliquot. Shake thoroughly before use.