Applications/Dilutions

25.4 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Buffer

20 mM Tris-HCl buffer (pH 7.5) containing 1 mM DTT, 10% glycerol

Preservative

No Preservative

Concentration

1 mg/ml

Purity

>95% pure by SDS-PAGE

Alternate Names for Recombinant Human VPS28 Protein

ESCRT-I complex subunit VPS28

H-Vps28

MGC60323

vacuolar protein sorting 28 (yeast)

vacuolar protein sorting 28 homolog (S. cerevisiae)

vacuolar protein sorting-associated protein 28 homolog

yeast class E protein Vps28p homolog

Background

VPS28 is involved in endosomal sorting of cell surface receptors via a multivesicular body/late endosome pathway. This protein is a subunit of the ESCRT-I complex (endosomal complexes required for transport) involved in the sorting of ubiquitinated proteins. VSP28 binding with the TSG101 may play important roles in budding of Retroviruses, such as HIV-1 and Ebola virus. Recombinant human VPS28 was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Contact Information

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