Our group is particularly inspired by natural products not only because of their importance as synthetic targets but also due to their ability to serve as invaluable identifiers of unanswered chemical, medicinal, biological, and biophysical questions. One major focus of our research has been the selective halogenation of alkenes. Dihalogenation and halofunctionalization encompass some of the most... More >

Autoionizing (or electron-detaching) states are ubiquitous in physics, chemistry, biology, and technology. Such meta-stable states (called resonances) play a central role in processes as diverse as DNA radiolysis, plasmonic catalysis, and attosecond spectroscopy. Resonances belong to the continuum spectrum, which makes their theoretical description exceptionally difficult, because their wave... More >

Never before have energy systems faced a greater transformation than today, and never before was energy  primarily electricity  so important. With a growing global population, rising economic output and, above all, ever more uses of electricity, the demand for electricity is expected to nearly double by mid-century. At the same time, the demand for greater system sustainability and affordable... More >

At the heart of most cancer immunotherapies are specific molecular interactions between the principle cancer cell killers, T cells, and the tumor-associated peptide antigens that are presented within the tumor environment.

I will discuss 2 separate projects relevant to understanding and harnessing these interactions. The first is a microchip/nanotech based single cell tool that is used for... More >