3.
Complications of the Blood
About half of SLE patients are anemic.
Antiphospholipids: Their actions have complex effects that include causing narrowing and abnormalities of blood vessels.
Thrombocytopenia &amp;Neutropenia
Theeffects on blood vessels have also been associated with confusion, headaches, and seizures. Leg ulcers can also develop.

4.
Patients who have APS have a very incidence of blood clots, which most often occur in the deep veins in the legs (32%). Blood clotting in turn puts patients at higher risk for stroke (13%) and pulmonary embolism (clots in the lungs) (9%).

5.
Raynaud&apos;s Phenomenon
Raynaud&apos;s phenomenon is a condition in which cold or stress can cause spasms in impaired blood vessels resulting in pain in fingers and toes. It occurs as part of the inflammatory response in blood vessels, which can narrow them and reduce circulation. In extreme cases, gangrene can result

6.
Heart &amp;Circulation Complications
Cardiovascular disease is a primary cause of death in lupus patients.
SLE treatments (particularly corticosteroids) affect cholesterol, weight, and other factors that can also affect the heart
Atherosclerosis.
Increased stiffness in the arteries.
Unhealthy cholesterol and lipid (fatty molecules) levels.

8.
Lung Complications
Inflammation of the membrane lining the lung (pleuritis) is the most common problem.
In some cases, fluid accumulates, a condition called pleural effusion, and can cause stabbing localized pain that worsens when coughing, sneezing, laughing, or taking a deep breath.
Inflammation of the lung itself in SLE is called lupus pneumonitis.

10.
Central Nervous System
Irritability.
Emotional disorders (anxiety, depression).
Mild impairment of concentration and memory.
Occasionally, the reflex systems, sensation, vision, hearing, and motor control can be affected.
The most serious CNS disorder is inflammation of the blood vessels in the brain, which occurs in 10% of SLE patients. Fever, seizures, psychosis, and even coma can occur.

13.
Eye Complications
Inflamed blood vessels in the eye can reduce blood supply to the retina, resulting in degeneration of nerve cells and a risk of hemorrhage in the retina. The most common symptoms are cotton-wool-like spots on the retina. In about 5% of patients sudden temporary blindness and ulcer may occur .