Dospinescu, Ciprian(The Robert Gordon University School of Pharmacy and Life Sciences, 2009-03)

In the pulmonary circulation, alveolar hypoxia contributes to blood flow regulation.
Hypoxic pulmonary vasoconstriction (HPV) involves both pulmonary arteries and
veins, but little is known of the contractile mechanisms ...

The oxidation of low-density lipoprotein (LDL) is thought to contribute to atherogenesis, which
is an inflammatory disease involving activation of phagocytic cells. Myeloperoxidase, an enzyme
which is able to produce ...

G protein coupled receptor 55 (GPR55) is expressed throughout the body, and although its exact physiological function is unknown, studies have suggested a role in the cardiovascular system. In particular, GPR55 has been ...

WAINWRIGHT, C. 2016. New insights into the yin and yang of the endocannabinoid system in health and disease. British journal of pharmacology [online], 173(7), pages 1113-1115. Available from: https://dx.doi.org/10.1111/bph.13451

This article is part of a themed section on Endocannabionoids, of which the author is guest editor. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v173.7/issuetoc.

The receptors mediating the hemodynamic responses to cannabinoids are not
clearly defined due to the multifarious pharmacology of many commonly used
cannabinoid ligands. While both CB1 and TRPV1 receptors are implicated, ...

Hepburn, Claire Y.(Robert Gordon University School of Pharmacy and Life Sciences., 2014-05)

The phytocannabinoid cannabidiol (CBD) has a complex pharmacology which is thought to include, but is not limited to, an ability to act as an inverse agonist at the CB1 and CB2 receptors and an antagonist of GPR55. Moreover, ...

Skene, Karen E.(The Robert Gordon University School of Pharmacy and Life Sciences., 2010-04)

Neointimal formation is a complex process that occurs due to the over compensatory healing
response produced by the vessel following injury. Three key events, SMC proliferation, SMC
migration and the inflammatory response, ...

Michel, Lisa(Robert Gordon University School of Pharmacy and Life Sciences, 2012-05)

The ω-3 polyunsaturated fatty acids (ω-3 PUFAs), eicosapentaenoic acid (EPA) and
docosahexaenoic acid (DHA), have been shown to have cardioprotective and antiatherosclerotic
actions. While it has been proposed that ω-3 ...