"American Dad! is a great fit for TBS, a favourite of comedy fans who like smart, irreverent humour with ample doses of biting wit and skewering satire," said Michael Wright, president and head of programming for TBS, TNT and Turner Classic Movies.

"We look forward to welcoming Seth MacFarlane and the rest of his team as they bring this iconic show to TBS."

Family Guy will be the sole remaining MacFarlane animated show on Fox, after The Cleveland Show was cancelled earlier this year.

MacFarlane was previously developing a reboot of The Flintstones for Fox, but the project has been indefinitely delayed.