Jeremy Kyle was left speechless with what he described as the most "shocking" DNA result "EVER".

The first segment of the episode saw Andrew refuse to accept his pre-op transsexual 'father' Jessie, who was born Shane, as a woman before a bigger bombshell was dropped as he discovered Jessie wasn't his biological dad.

Jeremy read out the surprising DNA result, and a shocked Jessie broke down in tears.

Jeremy read out the surprising DNA result, and a shocked Jessie broke down in tears (Image: ITV)

He told her: "You're not his biological father."

She then stood up and put her hands to her face as she started weeping.

Andrew said: "No matter what, you'll always be my dad."

Jeremy Kyle (centre) was left speechless as his show returned today after what he described as the most "shocking" DNA result "EVER" (Image: ITV)

But Jeremy appeared to be one of the most surprised people in the studio upon hearing the result.

He said: "I genuinely don't know what to say … I don't think I've ever been more shocked by a result."