The sudden death of a nurse who unwittingly accepted a prank call to a London hospital about Prince William's pregnant wife Kate has shocked Britain and Australia, and sparked an angry backlash Saturday from some who argue the DJs who carried out the hoax should be held responsible.

At first, the call by two irreverent Australian DJs posing as royals was picked up by news outlets around the world as an amusing anecdote about the royal pregnancy. Some complained about the invasion of privacy, the hospital was embarrassed, and the radio presenters sheepishly apologized.

But the prank took a dark twist Friday with the death of nurse Jacintha Saldanha, a 46-year-old mother of two, three days after she took the hoax call. Police have not yet determined Saldanha's cause of death, but people from London to Sydney have been making the assumption that she died because of stress from the call.

King Edward VII's Hospital, where the former Kate Middleton was being treated for acute morning sickness this week, wrote to the 2DayFM radio station's parent company Southern Cross Austereo, condemning the "truly appalling" hoax and urging it to take steps to ensure such an incident would never happen again.

Royal officials said Prince William and Kate were "deeply saddened" but insisted that the palace had not complained about the hoax. The hospital said it did not reprimand Saldanha.