These chemicals become vapors that can irritate the nose, throat, eyes and lungs, said Dr. Timothy Craig, an allergist and immunologist at Penn State Health.

"The nose provides a helpful warning signal," he added in a health system news release. "If someone's nose becomes irritated while cleaning, it's safe to assume his or her lungs will be irritated, too."

"We all clean with bleach and other chemicals from time to time," said Dr. Ann Bogdan, a family health physician from Penn State Health Medical Group-Mechanicsburg. "But I encourage my patients to be careful when doing so."

The doctors offer these six safety precautions while spring cleaning.

Don't combine chemical cleaners. "In particular, never mix ammonia and bleach," Bogdan said. This can result in dangerously toxic vapors.

While cleaning, be sure to have proper ventilation by opening a window or running a fan.

Wear rubber gloves. "Without them, you run the risk of developing redness or rashes on your hands," Craig said.

Try using old-fashioned cleaners. "Diluted vinegar works well to clean windows, and baking soda gives you scrubbing power," Bogdan said.

Read labels and look for volatile organic compounds and other potential irritants, even in products labeled as "green" or "healthy."

Look for products with the "Safer Choice" logo, which the U.S. Environmental Protection Agency deems as "safer for human health and the environment."

And their final advice: If you develop coughing, wheezing, throat soreness or eye watering while using chemical cleaners, step into another room or walk outside. If the symptoms persist even after leaving the room, call a doctor.