From what I've read, Nicotine seems to be a wonderful substance, with many many good effects, the only downsides are the addictivness and the OD risk...
But it's nowhere near as dangerous as tobacco, which contains lots of other stuff...

From wikipedia:
"The LD50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 40–60 mg can be a lethal dosage for adult human beings. This makes it an extremely deadly poison. It is more toxic than many other alkaloids such as cocaine, which has a lethal dose of 1000mg."

I bought a Nicotin inhalor, and instead of shooting Bupe with Nicotine, I tried to shoot Bupe, and then huff Nicotine from the inhalator...
It definitely increases the pleasure, but it doesn't increase the high (anyway I get no high from Bupe); with Nicotine I felt better...

While it is effective, in my opinion it is not worth the price of Nicotine (being an inhalor, a patch, a gum or a cig....)

I won't try it, sorry...
I would be very happy if someone would like to try it for me...

I experienced the potentiation of Buprenorphine by huffing Nicotine from a Nicotine inhalor (inhalator?) just after shooting Bupe; when doing that, both substances make their effects exactly at the same time...
So I experienced what I wanted to experiment, no need to try shooting Nicotine, which could be dangerous...

Anyway:
-When someone is addicted to Opiates and take his Opiate just to feel normal, but still feel the little pleasure it causes, the pleasure of relief I think, (something linked to Dopamine in the N. Accumbens?); taking Nicotine with his Opiate (smoked while shooting the Opiate or maybe shooting it with the Opiate...), increases this little pleasure, it's not an increased high, just a little pleasure....

"...The first modern scientific evidence for this conclusion appeared in the English medical journal Lancet in 1942. Dr. Lennox Johnston there reported that he had given small injections of nicotine solution to 35 volunteers, including himself. "Smokers almost invariably thought the sensation pleasant," Dr. Johnston declared, "and, given an adequate dose, were disinclined to smoke for a time thereafter.... After a course of 80 injections of nicotine, an injection was preferred to a cigarette." If the nicotine injections were abruptly discontinued, craving arose. Dr. Johnston found that in satisfying this craving, one milligram of injected nicotine was roughly the equivalent of smoking one cigarette. He concluded that "smoking tobacco is essentially a means of administering nicotine, just as smoking opium is a means of administering morphine."

Buy one... It's not that expansive, and very effective...
Only one huff gives you a strong head buzz...

not if you have tolerance/ addiction.
I don't want a quitting aid that provides 1/3 the plasma nicotine levels given by a cigarette, I want a cigarette substitute that gives the proper dose as quickly as a cigarette, but I know it would never get licenced.

Yeah, it's a deadly poison they say ('40–60 mg can be a lethal dosage for adult human beings'). Anyway they don't give a fuck about danger connected with shooting some shit from the street with unknown amount of desired drug.

more seriously 'ad libitum dosing' ie as much as you want when you want only results in peak plasma levels 1/3 that of a cigarette, its a case of partly how much but also how fast its delivered for the desirable effects. slow administration of large dose = unpleasant
fast adminsitration of low dose = OK
fast administration of reasonable dose= whats wanted

seems that the cigarette produces finely divided nicotine and vapour in the right size for rapid max absorbtion

Yes, but using the method I suggested would result in a greater rate of absorption and therefore would theoretically be more pleasurable. The nicotine from inhalators is in fact absorbed through the mucous membranes in the mouth rather than the lungs.

Correct me if I'm wrong, but I think the only reason inhalators are used is because people become addicted to the act of smoking itself (like a needle fixation) and using an inhalator simulates the smoking of a cigarette.

wikipedia
that's a pack of cigarettes. Be careful or just don't attempt it.

But what was said about nicotine absorbtion in cigarettes is true.. most major brands altered the pH to make it more basic and vaporize faster, giving cigarettes a fast rush.. It's safer in the moment and probably faster than injection. The corporations have you beat there already!