Kaito Daimon is a brilliant 16-year-old teenager who loves to solve puzzles. He acquires an enigmatic item called the Armband of Orpheus that allows him to fully utilize his brain, but that consequentially drains him completely. Currently attending Root Academy as an honor student, he is invited by the school principal to confront a secret organization named POG that creates deadly Sage Puzzles to protect invaluable treasures and challenge the select few individuals capable of facing them. Given the title of Einstein, Kaito battles against the mysterious group in order to keep a promise he made as a kid while at the same time he heads towards the ultimate test: the Divine Puzzle.