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Study finds asthmatics with Vitamin D deficiency are 25 percent more likely to experience acute attacksAsthma, which inflames and narrows the airways, has become more common in recent years. While there is no known cure, asthma can be managed with medication and by avoiding allergens and other triggers. A new study by a Tel Aviv University researcher points to a convenient, free way to manage acute asthmatic episodes—catching some rays outside.http://medicalxpress.com/news/2014-10-asthmatics-vitamin-d-deficiency-percent.html
ImmunologyTue, 28 Oct 2014 13:09:36 EDTnews333720567No added benefit proven for umeclidinium/vilanterol in COPDThe drug combination umeclidinium/vilanterol (trade name Anoro) has been approved since May 2014 for adults with chronic obstructive pulmonary disease (COPD). In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether this drug combination offers an added benefit over the appropriate comparator therapy.http://medicalxpress.com/news/2014-10-added-benefit-proven-umeclidiniumvilanterol-copd.html
MedicationsMon, 20 Oct 2014 09:53:41 EDTnews333017609ERS: Mepolizumab is glucocorticoid-sparing in asthma(HealthDay)—For patients with eosinophilic asthma, mepolizumab has a glucocorticoid-sparing effect and reduces exacerbations when administered intravenously or subcutaneously, according to two studies published online Sept. 8 in the New England Journal of Medicine to coincide with the European Respiratory Society's International Congress, held Sept. 6 to 10 in Munich.http://medicalxpress.com/news/2014-09-ers-mepolizumab-glucocorticoid-sparing-asthma.html
Inflammatory disordersTue, 09 Sep 2014 05:40:01 EDTnews329458004Common cholesterol drug greatly alters inflammatory response to common coldCold season may be just behind us, but a new discovery may shed light on how this common condition triggers asthma attacks. In a new research report published in the June 2014 issue of the Journal of Leukocyte Biology, researchers show that in individuals with asthma, statins significantly reduce the in vitro inflammatory response of human monocytes to rhinovirus (RV), the cause of the common cold. Not only does this discovery suggest that statins could help prevent or reduce the severity of asthma symptoms resulting from colds, but may also open the doors to further research into novel ways of controlling asthma attacks.http://medicalxpress.com/news/2014-06-common-cholesterol-drug-greatly-inflammatory.html
Inflammatory disordersMon, 02 Jun 2014 09:49:16 EDTnews320921105Elevated blood eosinophil levels are a risk factor for asthma exacerbationsIn adults with persistent asthma, elevated blood eosinophil levels may be able to predict which individuals are at increased risk for exacerbations, according to a new study presented at the 2014 American Thoracic Society International Conference.http://medicalxpress.com/news/2014-05-elevated-blood-eosinophil-factor-asthma.html
Diseases, Conditions, SyndromesTue, 20 May 2014 12:50:16 EDTnews319809006Study may explain link between antibiotic use in infants and asthma(Medical Xpress)—Children who receive antibiotics before their first birthday might be at a slightly increased risk of developing asthma. However, new research by The University of Manchester suggests that it is impaired viral immunity and genetic variants on a region of chromosome 17 that increase the risk of both antibiotic use in early life and later asthma rather than the antibiotics themselves, as previously thought.http://medicalxpress.com/news/2014-05-link-antibiotic-infants-asthma.html
ImmunologyThu, 15 May 2014 06:20:07 EDTnews319353587September peak month for kids' asthma flares, study finds(HealthDay)— Many parents know that allergies are seasonal, but fewer may realize that the same is true of asthma: A new study suggests the riskiest time for children with asthma is September, as they head back to school.http://medicalxpress.com/news/2014-03-september-peak-month-kids-asthma.html
Diseases, Conditions, SyndromesMon, 10 Mar 2014 17:50:01 EDTnews313691141Bronchial thermoplasty shows long-term effectiveness for asthmaThe beneficial effects of bronchial thermoplasty, a non-pharmacologic treatment for asthma, last at least five years, according to researchers at National Jewish Health and other institutions. The therapy, in which heat is applied to a patient's airways during a bronchoscopy procedure, was approved by the U.S. Food and Drug Administration in April 2010. Among other criteria, the researchers report in the December issue of the Journal of Allergy and Clinical Immunology that reductions in severe asthma exacerbations, emergency department visits, medication use and missed workdays continued out to five years after the procedure was performed.http://medicalxpress.com/news/2013-12-bronchial-thermoplasty-long-term-effectiveness-asthma.html
ImmunologyMon, 02 Dec 2013 15:47:00 EDTnews305221605Helping to reduce hospital admissions for COPD patientsPatients can use tablet computers to report their daily condition. Hospitals can pick up early symptoms, take action and thereby reduce admissions.http://medicalxpress.com/news/2013-09-hospital-admissions-copd-patients.html
Diseases, Conditions, SyndromesFri, 13 Sep 2013 08:50:03 EDTnews298280275Severe asthma patients less responsive to treatmentPeople with severe asthma, who are often described as 'steroid-dependent', are actually less likely to respond to the treatment they depend on, when compared to people with mild asthma.http://medicalxpress.com/news/2013-09-severe-asthma-patients-responsive-treatment.html
Inflammatory disordersMon, 09 Sep 2013 05:40:01 EDTnews297923388Traffic pollution and wood smoke increases asthma in adults(Medical Xpress)—Asthma sufferers frequently exposed to heavy traffic pollution or smoke from wood fire heaters, experienced a significant worsening of symptoms, a new University of Melbourne led study has found.http://medicalxpress.com/news/2013-08-traffic-pollution-wood-asthma-adults.html
HealthTue, 20 Aug 2013 06:47:16 EDTnews296200020Bioactive paper will revolutionize point-of-care diagnosticsA pair of University researchers have received a $600,000 CIHR award to develop a bioactive paper that aims to provide an inexpensive, point-of-care diagnostic tool to measure bronchitis in patients with airway diseases, such as asthma, COPD and chronic cough.http://medicalxpress.com/news/2013-07-bioactive-paper-revolutionize-point-of-care-diagnostics.html
Diseases, Conditions, SyndromesWed, 24 Jul 2013 06:20:05 EDTnews293864487Certain inflammatory biomarkers associated with increased risk of COPD exacerbationsSimultaneously elevated levels of the biomarkers C-reactive protein, fibrinogen and leukocyte count in individuals with chronic obstructive pulmonary disease (COPD) were associated with increased risk of having exacerbations, even in those with milder COPD and in those without previous exacerbations, according to a study in the June 12 issue of JAMA.http://medicalxpress.com/news/2013-06-inflammatory-biomarkers-copd-exacerbations.html
Inflammatory disordersTue, 11 Jun 2013 16:29:23 EDTnews290186954Monoclonal antibody appears effective and safe in asthma Phase IIa trialA novel approach to obstructing the runaway inflammatory response implicated in some types of asthma has shown promise in a Phase IIa clinical trial, according to U. S. researchers.http://medicalxpress.com/news/2013-05-monoclonal-antibody-effective-safe-asthma.html
Diseases, Conditions, SyndromesTue, 21 May 2013 09:24:57 EDTnews288347089New study identifies risk factors for depression among COPD patientsPatients suffering from chronic obstructive pulmonary disease (COPD) typically suffer from depression more frequently than those without COPD, resulting in higher levels of disability and illness and increasing the overall healthcare burden for the COPD population. Now, a study from researchers in Argentina indicates female COPD patients and patients who experience significant shortness of breath may have the greatest risk for developing depression.http://medicalxpress.com/news/2013-05-factors-depression-copd-patients.html
Diseases, Conditions, SyndromesMon, 20 May 2013 09:11:39 EDTnews288259890New research reveals swimming beneficial for young people with asthmaNew research by medical students working in the Breathe Well Centre of Research Excellence at the UTAS School of Medicine has revealed swimming has health benefits for young people with asthma, with no adverse effects on asthma control or exacerbations.http://medicalxpress.com/news/2013-05-reveals-beneficial-young-people-asthma.html
Inflammatory disordersFri, 10 May 2013 09:30:01 EDTnews287394678Allergic disease worsens respiratory symptoms and exacerbations in COPDPatients with chronic obstructive pulmonary disease (COPD) who also have allergic disease have higher levels of respiratory symptoms and are at higher risk for COPD exacerbations, according to a new study from researchers at Johns Hopkins University in Baltimore.http://medicalxpress.com/news/2013-05-allergic-disease-worsens-respiratory-symptoms.html
Diseases, Conditions, SyndromesFri, 10 May 2013 00:00:02 EDTnews287338973Azithromycin may provide benefit for treatment of respiratory disorderAmong patients with the lung disorder non-cystic fibrosis bronchiectasis, treatment with the antibiotic azithromycin resulted in improvement in symptoms but also increased the risk of antibiotic resistance, according to a study appearing in the March 27 issue of JAMA.http://medicalxpress.com/news/2013-03-azithromycin-benefit-treatment-respiratory-disorder.html
Diseases, Conditions, SyndromesTue, 26 Mar 2013 16:00:11 EDTnews283523037Japanese researchers identify a protein linked to the exacerbation of COPDResearchers from the RIKEN Advanced Science Institute and Nippon Medical School in Japan have identified a protein likely to be involved in the exacerbation of chronic obstructive pulmonary disease (COPD). This protein, Siglec-14, could serve as a potential new target for the treatment of COPD exacerbation.http://medicalxpress.com/news/2013-03-japanese-protein-linked-exacerbation-copd.html
Diseases, Conditions, SyndromesThu, 21 Mar 2013 11:38:17 EDTnews283084641Single combo inhaler beats standard rx in asthma(HealthDay)—Maintenance and reliever therapy with a single inhaled corticosteroid plus a rapid-onset, long-acting, β2 agonist (formoterol) seems beneficial for patients with asthma, according to two studies published in the March issue of The Lancet Respiratory Medicine.http://medicalxpress.com/news/2013-03-combo-inhaler-standard-rx-asthma.html
Diseases, Conditions, SyndromesTue, 05 Mar 2013 17:34:25 EDTnews281727258Bronchiectasis increases mortality risk in moderate-to-severe COPDBronchiectasis is independently associated with an increased mortality risk in patients with moderate-to-severe COPD, according to a new study from researchers in Spain.http://medicalxpress.com/news/2013-02-bronchiectasis-mortality-moderate-to-severe-copd.html
Diseases, Conditions, SyndromesFri, 08 Feb 2013 00:00:01 EDTnews279472696Added benefit of aclidinium bromide is not provenThe drug aclidinium bromide (trade names Eklira, Bretaris) has been approved since October 2012 for widening the narrowed airways of adults with chronic-obstructive pulmonary disease (COPD). The German Institute for Quality and Efficiency in Health Care (IQWiG) has now examined the added benefit of the drug pursuant to the "Act on the Reform of the Market for Medicinal Products" (AMNOG). No proof of an added benefit of aclidinium bromide compared with the appropriate comparator therapy (ACT) can be inferred from the data in the drug manufacturer's dossier.http://medicalxpress.com/news/2013-01-added-benefit-aclidinium-bromide-proven.html
MedicationsWed, 30 Jan 2013 09:38:03 EDTnews278760982Tiotropium has advantages for patients with COPDIn order to widen the narrowed airways in patients with chronic obstructive pulmonary disease (COPD), tiotropium bromide (tiotropium in brief) is one of the drugs available that can be prescribed for inhalation. The German Institute for Quality and Efficiency in Health Care (IQWiG) has examined whether tiotropium offers a perceptible advantage to patients compared to a dummy medication (placebo) and to other COPD drugs. In addition, the two currently marketed types of inhaler (HandiHaler and Respimat) for tiotropium (trade name: Spiriva) were compared.http://medicalxpress.com/news/2012-12-tiotropium-advantages-patients-copd.html
Diseases, Conditions, SyndromesTue, 11 Dec 2012 11:04:41 EDTnews274446271'Obesity paradox': Extra weight linked to better outcomes for septic shock, asthma exacerbationAlthough obesity is linked to a variety of health risks, new research indicates that obese patients may have an advantage over nonobese patients in certain health situations, including septic shock and acute asthma exacerbation.http://medicalxpress.com/news/2012-10-obesity-paradox-extra-weight-linked.html
Overweight and ObesityMon, 22 Oct 2012 03:58:41 EDTnews270097114Roflumilast improves lung function after 6 months compared with placeboRoflumilast was associated with significant improvements in lung function in patients with moderate and severe chronic obstructive pulmonary disease (COPD) after 6 months of treatment compared with placebo.http://medicalxpress.com/news/2012-10-roflumilast-lung-function-months-placebo.html
MedicationsMon, 22 Oct 2012 03:40:51 EDTnews270096033Smoking: Quitting is tough for teens, tooAbstinence from smoking seems to affect teens differently than adults in a couple ways, but a new study provides evidence that most of the psychological difficulties of quitting are as strong for relatively new, young smokers as they are for adults who have been smoking much longer.http://medicalxpress.com/news/2012-09-tough-teens.html
AddictionWed, 12 Sep 2012 16:09:05 EDTnews266684936Mild asthma patients may not need daily inhaled steroid therapy: studyFor two decades, asthma treatment for millions of people with a milder form of the disease has consisted of daily inhaled steroid medicine to reduce inflammation. Now, a new study has found that asthmatics who take the low-dose medication as a daily routine do no better than those who turn to their inhalers only when they have symptoms.http://medicalxpress.com/news/2012-09-asthma-big-daily-regimen.html
Inflammatory disordersTue, 11 Sep 2012 16:00:01 EDTnews266596608Antibiotic therapy improves moderate exacerbations of mild-to-moderate COPDAntibiotic treatment with amoxicillin/clavulanate improves moderate exacerbations in patients with mild-to-moderate chronic obstructive pulmonary disease (COPD) and significantly prolongs the time between exacerbations, according to a new study from researchers in Spain.http://medicalxpress.com/news/2012-09-antibiotic-therapy-moderate-exacerbations-mild-to-moderate.html
Diseases, Conditions, SyndromesFri, 07 Sep 2012 12:43:47 EDTnews266240616Children exposed to two phthalates have elevated risk of asthma-related airway inflammationChildren exposed to diethyl phthalate (DEP) and butylbenzyl phthalate (BBzP)—phthalate chemicals commonly found in personal care and plastic products—have elevated risk of asthma-related airway inflammation, according to researchers at Columbia Center for Children's Environmental Health (CCCEH) at the Mailman School of Public Health.http://medicalxpress.com/news/2012-09-children-exposed-phthalates-elevated-asthma-related.html
ImmunologyWed, 05 Sep 2012 12:40:38 EDTnews266067630Addition of tiotropium effective in poorly controlled asthma(HealthDay)—For patients with poorly controlled asthma, the addition of tiotropium to standard therapy is beneficial, according to a study published online Sept. 3 in the New England Journal of Medicine to coincide with presentation at the annual meeting of the European Respiratory Society, held from Sept. 1 to 5 in Vienna.http://medicalxpress.com/news/2012-09-addition-tiotropium-effective-poorly-asthma.html
ImmunologyTue, 04 Sep 2012 17:00:11 EDTnews265995789