Tag: meta-analysis

Meta-analyses can sometimes suffer from the "GIGO problem" (garbage in, garbage out). The publication of a "crappy" acupuncture "network meta-analysis" for acupuncture and chronic constipation illustrates the GIGO problem on steroids and reveals a problem with peer review.

The New York Times had to go an publish "For Bad Backs, It May Be Time to Rethink Biases About Chiropractors" right after my Friday extravaganza, "Spinal Manipulation and the JAMA Meta-Analysis: An Analysis of Fuel. Sigh. Doody [sic] Calls.

It’s been difficult to avoid the buzz about vitamin D over the past few years. While it has a long history of use in the medical treatment of osteoporosis, a large number of observational studies have linked low vitamin D levels to a range of illnesses. The hypothesis that there is widespread deficiency in the population has led to interest in measuring...

Two recently published meta-analyses, one on meat and another on milk, conclude that levels of polyunsaturated fatty acids (PUFA) and omega-3 fatty acids are higher in the organic versions of both. This is being widely reported as evidence that organic meat and milk is healthier, but a closer look at these two studies shows a different picture. The organic false dichotomy I...

I don’t know the best metaphor. What comes around goes around. The more things change, the more they say the same. Sisyphus. Whack-A-Mole. So what to do when the same old same old rears its head yet again? There are 2,545 posts on this blog, and I suppose I could just point to prior posts. But a blog entry that consists of...

"Electromagnetic hypersensitivity" and "wifi allergies" are two names given to a nonexistent medical condition in low energy electromagnetic fields like wifi are blamed for a variety of health conditions. This is a story in which the parents' insistence that their teenage daughter, who had posted threats to commit suicide on social media, had this condition appears to have interfered with seeking mental...

A new systematic review published in the International Journal of Obesity looks at the totality of evidence investigating whether consuming low energy sweeteners (LES), such as aspartame, sucralose, or stevia, is a net benefit or detriment for weight control. In addition to providing some clarity on the answer, the review also provides some insight into how different kinds of evidence address such...

One of the most contentious questions that come up in science-based medicine that we discuss on this blog is the issue of screening asymptomatic individuals for disease. The most common conditions screened for that we, at least, have discussed on this blog are cancers (e.g., mammography for breast cancer, prostate-specific antigen screening for prostate cancer, ultrasound screening for thyroid cancer), but screening...