Greg Widseth didn’t know what hit him. The Polk County attorney felt fine as he coached his son’s ninth-grade basketball workout last March. He remembers smiling at a young woman as he left the building. Now Widseth, who once had a photographic memory, is struggling to reconstruct the events that put him in the hospital and led his wife, a former emergency room nurse, to seek help from the Mayo Clinic… When it became clear that her husband wasn’t getting better, she called her sister in Rochester, whose neighbor happened to be Dr. Jeffrey Britton, a Mayo neurologist specializing in autoimmune encephalitis. Britton and his colleague, Dr. Andrew McKeon, a neuroimmunologist, agreed to see Widseth within a few days.

Reach: The Star Tribune Sunday circulation is 518,745 copies and weekday circulation is 300,277. The Star Tribune is the state’s largest newspaper and ranks 16th nationally in circulation.

BloombergNew Alzheimer's Research Throws Cold Water on Biogen's Recent Breakthrough by Cynthia Koons

Just days after Biogen Inc. revealed promising early data from an experimental Alzheimer’s treatment, new research from the Mayo Clinic may revive a long-running debate over whether the drug industry is focusing on the right target in developing therapies to treat the disease… “Amyloid has a relationship with cognitive decline, but if you’re looking at both of them together, tau is the bad guy,” Melissa Murray, a neuroscientist at the Mayo Clinic campus in Jacksonville, Florida, said in a telephone interview. The majority of research into the disease has focused on beta amyloid over the past 25 years, she said.

Reach:Bloomberg has 2,300 media professionals in 146 bureaus across 72 countries. Bloomberg delivers its content across more than 400 publications, over 310 million households worldwide through Bloomberg Television and 500,000 in the New York metro area and 18.5 million subscribers through satellite radio.

Context: By examining more than 3,600 postmortem brains, researchers at Mayo Clinic’s campuses in Jacksonville, Florida and Rochester, Minnesota have found that the progression of dysfunctional tau protein drives the cognitive decline and memory loss seen in Alzheimer’s disease. Amyloid, the other toxic protein that characterizes Alzheimer’s, builds up as dementia progresses, but is not the primary culprit, they say. The findings, published in Brain, offer new and valuable information in the long and ongoing debate about the relative contribution of amyloid and tau to the development and progression of cognitive dysfunction in Alzheimer’s, says the study’s lead author, Melissa Murray, Ph.D., a neuroscientist at Mayo Clinic in Jacksonville. More information can be found on Mayo Clinic News Network.

If you suffer from migraine headaches, you're not alone. More than 10% of the population is hurting right along with you, including 18% of women. Migraines are most common from the ages of 25 to 55. The good news: New research can help change your approach to managing your migraines. Here are five strategies to try… If you experience a strong smell like perfume, flickering or flashing lights, less sleep and you eat a cold-cut sub with nitrates all in one day, yes, you may get a migraine, but if you ate that sub on a day when you didn't experience those other triggers, you might be just fine," said Dr. Fred Cutrer, a neurologist at the Mayo Clinic in Rochester, Minn., in an interview.

Reach:The Los Angeles Timeshas a daily readership of 1.9 million and 2.9 million on Sunday, more than 8 million unique latimes.com visitors monthly and a combined print and online local weekly audience of 4.5 million. The Pulitzer Prize-winning Times has been covering Southern California for more than 128 years.

ReutersUncommon form of heart attack likely runs in family – study by Sharon Begley

… In the new study, in JAMA Internal Medicine, researchers at the Mayo Clinic combed a registry of patients who had suffered spontaneous coronary artery dissection (SCAD), in which one layer of a coronary artery splits off from another like cheap laminate. Blood seeps out between the arterial layers, starving the heart of oxygen and causing chest pain. If not treated quickly, it can cause heart attack and sometimes death…That is a problem because treatment for common heart attack - clearing arterial blockages - can worsen SCAD. Some 30 percent to 40 percent of SCADs should be left to heal on their own, said Mayo's Dr. Sharonne Hayes, who led the study.

Context: A Mayo Clinic study has identified a familial association in spontaneous coronary artery dissection, a type of heart attack that most commonly affects younger women, suggesting a genetic predisposition to the condition, researchers say. The results are published in the March 23 issue of JAMA Internal Medicine. Researchers used the Mayo Clinic SCAD Registry of 412 enrollees to identify five familial cases of SCAD, comprised of three pairs of first-degree relatives (mother-daughter, identical twin sisters, sisters) and two pairs of second-degree relatives (aunt and niece, and first cousins). Researchers believe this is the first study to identify SCAD as an inherited disorder. More information, including a video interview with Sharonne Hayes, M.D., the study's senior author and a cardiologist can be found on Mayo Clinic News Network.

“You can feel it,” Charles Okeke says. “It’s pounding. If I opened my mouth, it was very audible.” Okeke is remembering the days when his blood was pumped by a massive 400-pound machine. It was one stage in a remarkable journey that has finally brought him where he is today — a healthy man with a healthy heart once again beating in his chest…“Charles was very sick when he showed up at our hospital,” remembers Eric Steidley, MD, a cardiologist at Mayo Clinic. “Charles was going to die unless we did something.”

Reach:Everyday Health Media, LLCis a provider of online consumer health content across a broad portfolio of over 25 websites that span the health spectrum — from lifestyle offerings in pregnancy, diet and fitness to in-depth medical content for condition prevention and management.

Context: For almost two years, Charles Okeke lived in a Mayo Clinic hospital tethered to a machine. He had just turned 30 when a blood clot destroyed his heart.

Context: Thousands of people come to Mayo Clinic's campus in Jacksonville, Fla., annually for diagnosis or treatment of a medical condition. In Florida, Mayo Clinic primarily treats adults, although some specialists see teenagers and children. Doctors in the Primary Care centers treat people of all ages. Many people make their own appointments and some are referred by a doctor. Mayo Clinic doctors can work closely with your hometown doctor to coordinate your care.

Dr. Ronald Petersen did not promise the Senate Special Committee on Aging a cure for Alzheimer’s disease in 10 years. But on Wednesday, the Mayo Clinic’s director of Alzheimer’s research held out hope for highly effective treatments in a decade if the government significantly increases its investment in research. Last year, Alzheimer’s, the disease that has become the curse of 5.3 million Americans and the fear of tens of millions more, received less than $600 million in research funding. That compares with $5.3 billion for cancer, $3 billion for HIV/AIDS and $2 billion for heart disease.

Reach: The Star Tribune Sunday circulation is 518,745 copies and weekday circulation is 300,277. The Star Tribune is the state’s largest newspaper and ranks 16th nationally in circulation.

Context:Ron Petersen, M.D., Ph.D., is the Cora Kanow Professor of Alzheimer’s Disease Research at Mayo Clinic. Dr. Petersen is regularly sought out by reporters as a leading expert in his medical field. Dr. Petersen chairs the Advisory Council on Alzheimer’s Research, Care and Services. Dr. Petersen testifed this week at the Senate Special Committee on Aging.

…Research has found that metformin targets the chemicals produced by age-related senescent cells—normal cells that stop dividing and produce toxic substances damaging to the cells around them, said James Kirkland, director of the Robert and Arlene Kogod Center on Aging at the Mayo Clinic in Rochester, Minn., and part of the TAME planning team. Senescent cells usually develop as people age or at sites of age-related chronic diseases, such as the brain in Alzheimer’s patients or around the plaques that lead to heart attacks and strokes, he said.

Reach: The Wall Street Journal, a US-based newspaper published by Dow Jones & Company, has the largest print circulation in America with 1.4 million (60 percent) of a total of 2.3 million. Its website has more than 4.3 million unique visitors each month.

Context: A new class of drugs identified and validated by Mayo Clinic researchers along with collaborators at Scripps Research Institute and others, clearly reduces health problems in mice by limiting the effect of senescent cells — cells that contribute to frailty and diseases associated with age. The researchers say this is a first step toward developing similar treatments for aging patients. Their findings appear in the journal Aging Cell.“If translatable to humans — which makes sense as we were using human cells in many of the tests – this type of therapy could keep the effects of aging at bay and significantly extend the healthspan of patients,” says James Kirkland, M.D., Ph.D., head of the Mayo Clinic Kogod Center on Aging and senior author of the study.

Huffington PostStruggling With High Blood Pressure? Your Sleep May Be To Blame by Alena Hall

Looking to lower your blood pressure? Fix your poor sleep habits first, suggests a new study. Mayo Clinic researchers recently set out to find how reduced sleep quantity and quality could affect a person's blood pressure. After monitoring their eight participants for 16 days, they found that when their subjects experienced prolonged periods of shorter sleep, they also registered substantially higher blood pressure numbers at night. While the size of the study was small, they presented their findings at the American College of Cardiology's 64th Annual Scientific Session in San Diego, California, on March 15.

Context: Healthy young adults who don’t consume caffeine regularly experienced greater rise in resting blood pressure after consumption of a commercially available energy drink — compared to a placebo drink — thus raising the concern that energy drinks may increase the risk of cardiac events, Mayo Clinic researchers found. More information can be found on Mayo Clinic News Network.

Doctors and hospitals urged support Friday for a bill that would make it simpler and faster for physicians to become licensed in multiple states…Dr. Steve Ommen, medical director of the Center for Connected Care at Mayo Clinic, said specialists are often called upon to advise doctors treating critically ill patients in other states. But the collaboration hinges on whether the specialist on duty has a license to practice in that state, Ommen said.

Reach:Minnesota Public Radio operates 43 stations and serves virtually all of Minnesota and parts of the surrounding states. MPR has more than 100,000 members and more than 900,000 listeners each week, which is the largest audience of any regional public radio network.

It is impressive to see and hear about what 3D printers can create. Some printers create toys or machine parts, and some duplicate human body parts for Mayo Clinic. "I've never been a patient before; I've been healthy my entire life,” said Michael Slag, who despite never smoking, was diagnosed with lung cancer. The body part being made by the printer is Michael Slag’s right chest plate. It shows his tumor that was attached to his lung and ribs. This model helped Michael better understand what was to come…"So the model actually shows us very clearly where the tumor may be and where the tumor is not," Shanda Blackmon told me as I held the three-dimensional model. Blackmon is a thoracic surgeon for Mayo Clinic and is one of Michael's doctors.

Reach:KAAL is owned by Hubbard Broadcasting Inc., which owns all ABC Affiliates in Minnesota including KSTP in Minneapolis-St. Paul and WDIO in Duluth. KAAL, which operates from Austin, also has ABC satellite stations in Alexandria and Redwood Falls. KAAL serves Southeast Minnesota and Northeast Iowa.

ABC 15 ArizonaMayo Clinic experts explain when cardiac testing is needed before surgery and when it is unnecessary

John Lynch, M.D., Mayo Clinic Cardiologist, joined the cast of Sonoran Living Live to discuss pre-surgical cardiac evaluations. When are cardiac evaluations necessary? When are they not necessary? Find out about pre-surgical cardiac evaluations and heart disease and treatment by joining ABC15's Rally for Red, and from Mayo Clinic staff members each month on Sonoran Living Live.

Mayo Clinic in the News is a weekly highlights summary of major media coverage. If you would like to be added to the weekly distribution list, send a note to Laura Wuotila with this subject line: SUBSCRIBE to Mayo Clinic in the News.

To financial analysts, the outlook for hospitals has been tilting negative. Demand for inpatient care is soft. Insurers and the government want to pay less for each service. New payment arrangements ask hospitals to take a degree of financial risk that patient costs exceed expectations. Against that backdrop, the record-setting financial results the Mayo Clinic released last week stand out…But the average length of stay for a Mayo Clinic hospital patient increased from 4.6 days in 2013 to 4.8 days last year. The change was significant because it signified that patients were sicker last year, and needed more revenue-producing services, said Jeff Bolton, the clinic’s chief administrative officer.

Reach: The Star Tribune Sunday circulation is 518,745 copies and weekday circulation is 300,277. The Star Tribune is the state’s largest newspaper and ranks 16th nationally in circulation.

Context: Mayo Clinic reports a strong 2014 performance, including providing direct care for more than 1.3 million people, contributions of $410 million to its pension plan as a commitment to employees, and plans for a $1.5 billion investment to fund information technology infrastructure. “Whether viewed through the lens of quality, patient outcomes, research advances, operational performance or sharing our knowledge with the world — by all measures, we had an extraordinary year,” says John Noseworthy, M.D., president and CEO, Mayo Clinic. “That success allowed us to reinvest in our people, our infrastructure and our mission so we can better serve our patients.” More information about Mayo's 2014 performance can be found on Mayo Clinic News Network.

The Independent UKSenolytics: Scientists identify new drug that slows the aging process and could dramatically increase our life expectancyby Christopher Hooton

A new class of drugs has been identified that slow the aging process in mice, alleviating symptoms of frailty and extending a healthy lifespan. If their effect on humans is as marked as it is on animal models, their benefit could be enormous. The research was carried out by a team from Mayo Clinic, The Scripps Institute and other institutions and published in the journal Aging Cell yesterday…"The prototypes of these senolytic agents have more than proven their ability to alleviate multiple characteristics associated with aging," added Mayo Clinic Professor James Kirkland, MD, who also worked on the study.

Reach:The Independentis a United Kingdom-based newspaper with a daily circulation of more than 61,000.

Context: A new class of drugs identified and validated by Mayo Clinic researchers along with collaborators at Scripps Research Institute and others, clearly reduces health problems in mice by limiting the effect of senescent cells — cells that contribute to frailty and diseases associated with age. The researchers say this is a first step toward developing similar treatments for aging patients. Their findings appear today in the journal Aging Cell.“If translatable to humans — which makes sense as we were using human cells in many of the tests – this type of therapy could keep the effects of aging at bay and significantly extend the healthspan of patients,” says James Kirkland, M.D., Ph.D., head of the Mayo Clinic Kogod Center on Aging and senior author of the study. More information about the study, including a video interview with Dr. Kirkland, can be found on Mayo Clinic News Network.

Larry Lee came close to death when a bloodclot lodged in his brain last year while walking his dog in rural Minnesota. Since his local hospital lacked the expertise to deal with the problem, it turned to the renowned Mayo Clinic. From a computer console at Mayo’s campus 65 miles away, a neurologist appeared via teleconference, took control of a robotic camera to examine Mr. Lee and shepherded the local team’s efforts to bust the clot…“We could see 10 years ago that healthcare was going to go through a period of great change,” says John Noseworthy, chief executive of Mayo. “So we said: ‘Let’s digitize our knowledge, digitize our work, knit together like-minded institutions and connect with them electronically’.”

The Reach: The Financial Timeshas a combined paid print and digital circulation of 690,000.

Context: Mayo’s Stroke Telemedicine Program allows stroke specialists to remotely evaluate people who’ve had acute strokes and make diagnoses and treatment recommendations working with emergency medicine doctors at other sites. Having a prompt neurological evaluation increases the possibility that a patient will receive clot-dissolving therapies or other interventions in time to reduce disability and death from stroke. The program began in Arizona, and now is represented nationally, with hubs in Arizona, Florida and Minnesota that serve more than 20 health care institutions in seven states. To read more about Larry Lee's story and the role his dog had in saving his life, go to Mayo Clinic's In the Loop.

Job seekers looking to find employment with a top-notch company need not look very far: the Rochester-based Mayo Clinic is among the nation’s best places to work—and they’re hiring—according to Fortune. The state’s largest private employer, based out of Rochester, was named among the 25 best companies hiring (it ranked 73rd overall on Fortune’s “2015 Best Companies” list) and has nearly 2,000 openings available across southeast and southern Minnesota.

Reach:Twin Cities Businessis a monthly business magazine with a circulation of more than 30,000 and more than 74,000 readers. The magazine also posts daily business news on its website.

Context:Fortunemagazine named Mayo Clinic to its list of the “100 Best Companies to Work For” in 2015. This is Mayo’s 12th consecutive year on the magazine’s annual compilation of companies that rate high with employees. The list ranks Mayo Clinic 73 overall among the top 100 companies. “We congratulate our employees for earning Mayo Clinic this distinction,” says John H. Noseworthy, M.D., president and CEO of Mayo Clinic. “We hope they take great pride in this ‘100 Best’ national recognition.” More information can be found on Mayo Clinic News Network.

Star TribuneRisks, benefits weighed in JAMA study on valve replacement
By Joe Carlson
In the first analysis of mass commercial use of a new minimally invasive therapy for a narrowed heart valve, researchers reported Tuesday that nearly 24 percent of patients died within a year of treatment...“Transcatheter aortic valve replacement has become transformational for patients who need a new valve and are at high risk for surgery or inoperable. But we have been lacking long-term data for this group of patients who are considering this procedure,” said a statement from Dr. David Holmes Jr., the interventional cardiologist at the Mayo Clinic who was lead author of the study in the Journal of the American Medical Association.

Reach: The Star Tribune Sunday circulation is 518,745 copies and weekday circulation is 300,277. The Star Tribune is the state’s largest newspaper and ranks 16th nationally in circulation.

Context: Study results of one-year data for more than 12,000 patients who had transcatheter aortic valve replacement (TAVR) in the United States show an overall one-year death rate of 23.7 percent and a stroke rate of 4.1 percent, according to a study published in the March 10 issue of JAMA. “Transcatheter aortic valve replacement has become transformational for patients who need a new valve and are at high-risk for surgery or inoperable. But we have been lacking long-term data for this group of patients who are considering this procedure,” says study lead authorDavid R. Holmes, Jr., M.D., a Mayo Clinic interventional cardiologist. “Before this study, we only had 30-day information. This is a milestone and will help us better guide patients and learn as physicians.” More information about the study can be found on Mayo Clinic News Network.

Mayo Clinic in the News is a weekly highlights summary of major media coverage. If you would like to be added to the weekly distribution list, send a note to Laura Wuotila with this subject line: SUBSCRIBE to Mayo Clinic in the News.

Health magazineWatch a Blind Grandfather ‘See’ His Wife and Family Again Thanks to a Bionic Eyeby Rachel Swalin

After losing his vision to a degenerative eye disease, a 68-year-old Minnesota grandfather of 10 can now make out the forms of his wife and family for the first time in a decade, NBC News reported. And it’s all thanks to one fascinating piece of technology…Raymond Iezzi Jr., MD, a Mayo Clinic researcher and ophthalmologist, had been treating Zderad’s grandson, who’s in the early stages of the disease, which is caused by genetic defects and is often passed on through families. Knowing Zderad’s eyesight had been lost to the disease, Dr. Iezzi suggested that the grandfather take part in a clinical trial for a device called the Second Sight Argus II, better known as a bionic eye. “Tell your grandfather I’d like to see him,” Dr. Iezzi told the boy, according to a Mayo Clinic release.

Reach:Healthmagazine has a monthly circulation of 1.3 million and Health.com delivers information that puts health into context in peoples' lives.

Context: It’s a medical story, a science and technology advancement and a romance wrapped into one moment: when a man who is blind sees his wife again for the first time in a decade. Allen Zderad began to have serious vision problems about 20 years ago due to retinitis pigmentosa, a degenerative eye disease affecting the retina. There is no effective treatment or cure. It ended his professional career and after a decade he was effectively blind, unable to see anything other than very bright light. He adjusted, even continuing woodworking by developing his sense of touch and spatial relationships. But he was unable to see his family, including ten grandchildren or his wife, Carmen. More information can be found on Mayo Clinic News Network.

Jacksonville Business JournalA vision for improving quality, driving down costs: Meet the new leader of Mayo Clinic Jacksonville by Colleen Michele Jones

It's easy to see why Dr. Gianrico Farrugia was chosen to lead Mayo Clinic's campus in Jacksonville, replacing Dr. Bill Rupp who retired last December. By turns warm and personable, intense and passionate, Farrugia practically lights up when talking about the future of the renowned institution, particularly here in Northeast Florida.

U.S. News & World Report recently named the Mayo Clinic in Rochester, Minnesota, the number one hospital in the country this year, a first for the hospital. The Mayo Clinic is world famous for a model that pays doctors salaries instead of fees, to head off the possibility of physicians ordering unnecessary tests to pad their incomes. Physicians also work on teams for better communication, and to keep costs down. The Mayo Clinic has been center stage in the debate over the Affordable Care Act and “bending the curve” on the high cost of healthcare in the U.S. Here & Now’s Robin Young speaks with Dr. John Noseworthy, president and CEO of the Mayo Clinic, who says “it’s that team-based, patient-centeredness that drives us forward.”

Reach: A live production of NPR and WBUR Boston, in collaboration with public radio stations across the country, Here & Now reflects the fluid world of news as it’s happening in the middle of the day, with timely, smart and in-depth news, interviews and conversation.

…Bart Demaerschalk, a neurologist and medical director of Mayo Clinic’s Center for Connected Care in Phoenix, says remote consultations are “the next best thing to having a live stroke team, and in terms of time we are just as fast.” The Mayo Clinic Telestroke Network has three hubs in Arizona, Florida and Minnesota which serve 38 “spoke” hospitals in nine states.

Reach: The Wall Street Journal, a US-based newspaper published by Dow Jones & Company, has the largest print circulation in America with 1.4 million (60 percent) of a total of 2.3 million. Its website has more than 4.3 million unique visitors each month.

Context: Bart Demaerschalk, M.D. is a Mayo Clinic neurologist. In stroke telemedicine, also called telestroke, doctors who have advanced training in the nervous system (neurologists) remotely evaluate people who've had acute strokes and make diagnoses and treatment recommendations to emergency medicine doctors at other sites. Doctors communicate using digital video cameras, Internet telecommunications, robotic telepresence, smartphones and other technology.

Operating income jumped by more than one-third last year at Mayo Clinic, as the Rochester-based hospital and clinic system posted its strongest performance in more than 25 years. The volume of patients seeking care from Mayo Clinic was strong, including sicker patients who stayed longer than anticipated, said Chief Financial Officer Kedrick Adkins Jr. At the same time, tight control on expenses meant that Mayo Clinic provided the care without a significant increase in labor costs, Adkins said.

Reach: The Star Tribune Sunday circulation is 518,745 copies and weekday circulation is 300,277. The Star Tribune is the state’s largest newspaper and ranks 16th nationally in circulation.

Context: Mayo Clinic reports a strong 2014 performance, including providing direct care for more than 1.3 million people, contributions of $410 million to its pension plan as a commitment to employees, and plans for a $1.5 billion investment to fund information technology infrastructure. “Whether viewed through the lens of quality, patient outcomes, research advances, operational performance or sharing our knowledge with the world — by all measures, we had an extraordinary year,” says John Noseworthy, M.D., president and CEO, Mayo Clinic. “That success allowed us to reinvest in our people, our infrastructure and our mission so we can better serve our patients.” More information about Mayo's 2014 performance can be found on Mayo Clinic News Network.

Mayo Clinic in the News is a weekly highlights summary of major media coverage. If you would like to be added to the weekly distribution list, send a note to Laura Wuotila with this subject line: SUBSCRIBE to Mayo Clinic in the News.

Man gains sight with bionic eye, Allen Zderad was recently able to see his wife of 45 years for the first time in a decade. The Minnesota man seemed to burst into simultaneous laughter and tears as he caught a glimpse of her with his new "bionic eye."… Now with the help of a recently developed medical device, Zderad's vision of the world has changed. He's one of just a handful of people in the world to get the "bionic eye" device known as Second Sight Argus II retinal prosthesis system. Zderad's was implanted by Dr. Raymond Iezzi of the Mayo Clinic.
Reach:CBSNEWS.comis part of CBS Interactive, a division of CBS Corporation. The CBS web properties have more than 250 million people visit its properties each month.

A Minnesota man who had a bionic eye implant is seeing his wife for the first time in ten years. So he can now make out forms and shapes and send a signal to his optic nerve. His sight began to fail just 20 years ago. Now Diane is commenting on the Mayo Clinic’s Facebook page, writing “you are really awesome, Mayo Clinic.” He said seeing the wife for the first time. First time in ten years.
Reach:CNN.com has 74.2 million unique visitors to its website each month.

It was love again at first sight for a man who went blind 10 years ago. Allen Zderad, a 68-year-old retiree from Minnesota, saw his wife for the first time in more than a decade thanks to a bionic eye implanted by doctors at the Mayo Clinic earlier this month.

Reach: ABCNews.com is the official website for ABC News. Its website receives more than 16.9 million unique visitors each month.

Context: It’s a medical story, a science and technology advancement and a romance wrapped into one moment: when a man who is blind sees his wife again for the first time in a decade. Allen Zderad began to have serious vision problems about 20 years ago due to retinitis pigmentosa, a degenerative eye disease affecting the retina. There is no effective treatment or cure. It ended his professional career and after a decade he was effectively blind, unable to see anything other than very bright light. He adjusted, even continuing woodworking by developing his sense of touch and spatial relationships. But he was unable to see his family, including ten grandchildren or his wife, Carmen. More information can be found on Mayo Clinic News Network.

…Past versions of MBI exposed patients to too much radiation to use for regular screenings. A new version developed at the Mayo Clinic in Rochester, Minn., uses a lower dose. In a study of 1,585 women with dense breasts published in the American Journal of Roentgenology this month, Deborah Rhodes, a Mayo Clinic internist, and colleagues found that MBI detected nearly four times as many invasive breast cancers as mammography, with fewer unnecessary biopsies. As of now, only about 100 hospitals offer the newest MBI technology, which is made by GE Healthcare and Gamma Medica Inc.

Reach: The Wall Street Journal, a US-based newspaper published by Dow Jones & Company, has the largest print circulation in America with 1.4 million (60 percent) of a total of 2.3 million. Its website has more than 4.3 million unique visitors each month.

Context: A new breast imaging technique pioneered at Mayo Clinic nearly quadruples detection rates of invasive breast cancers in women with dense breast tissue, according to the results of a major study published recently in the American Journal of Roentgenology. Molecular Breast Imaging (MBI) is a supplemental imaging technology designed to find tumors that would otherwise be obscured by surrounding dense breast tissue on a mammogram. Tumors and dense breast tissue can both appear white on a mammogram, making tumors indistinguishable from background tissue in women with dense breasts. About half of all screening-aged women have dense breast tissue, according to Deborah Rhodes, M.D., a Mayo Clinic Breast Clinic physician and the senior author of this study. More information can be found on Mayo Clinic News Network.

A research team led by investigators from Mayo Clinic’s campus in Jacksonville and the University of Oslo in Norway have identified a molecule that pushes normal pancreatic cells to transform their shape, laying the groundwork for development of pancreatic cancer — one of the most difficult tumors to treat.

Context: A research team led by investigators from Mayo Clinic’s campus in Jacksonville, Florida, and the University of Oslo, Norway, have identified a molecule that pushes normal pancreatic cells to transform their shape, laying the groundwork for development of pancreatic cancer — one of the most difficult tumors to treat. Their findings, reported in Nature Communications, suggest that inhibiting the gene, protein kinase D1 (PKD1), and its protein could halt progression and spread of this form of pancreatic cancer, and possibly even reverse the transformation. More information can be found on Mayo Clinic News Network.

Mayo Clinic in the News is a weekly highlights summary of major media coverage. If you would like to be added to the weekly distribution list, send a note to Laura Wuotila with this subject line: SUBSCRIBE to Mayo Clinic in the News.

A technological breakthrough is allowing a grandfather who's been blind for 10 years to see again.

Reach:USA TODAY has the highest daily circulation of any U.S. newspaper with a daily average circulation of 4.1 million, which includes print, various digital editions and other papers that use their branded content.

A blind Forest Lake man's sight is restored after he became the first person in Minnesota, and 15th person in the country, to receive a bionic eye…Allen Zderad, 68, hadn't seen his wife or grandchildren in more than a decade, until the new device was turned on at Mayo Clinic earlier this month. “Yeah," Zderad exclaimed, as his wife of 45 years slowly came into focus. He then could find no more words, embracing her. "It's crude, but it's significant. It works," he rejoiced, through tears.

Context: Raymond Iezzi, Jr., M.D., is a Mayo Clinic ophthalmologist. Mayo Clinic eye experts provide comprehensive care for people who seek answers about conditions and diseases of their eyes. Each year doctors in the Mayo Clinic Department of Ophthalmology help nearly 80,000 people who need healing. Dr. Iezzi's clinical interests include retinal degenerative diseases as well as all aspects of vitreoretinal surgery, with a special interest in complex retinal detachment repair associated with diabetes, trauma and proliferative vitreoretinopathy.

Critics have long faulted U.S. medical education for being hidebound, imperious and out of touch with modern health-care needs. The core structure of medical school—two years of basic science followed by two years of clinical work—has been in place since 1910. Now a wave of innovation is sweeping through medical schools, much of it aimed at producing young doctors who are better prepared to meet the demands of the nation’s changing health-care system…. “The reality is that most medical schools are teaching the same way they did one hundred years ago,” says Wyatt Decker, chief executive of the Mayo Clinic’s operations in Arizona, which include a medical school in Scottsdale, Ariz., that is scheduled to enroll its first class in 2017. “It’s time to blow up that model and ask, ‘How do we want to train tomorrow’s doctors?’ ”

Reach: The Wall Street Journal, a US-based newspaper published by Dow Jones & Company, has the largest print circulation in America with 1.4 million (60 percent) of a total of 2.3 million. Its website has more than 4.3 million unique visitors each month.

Every year, the pharmaceutical industry spends more than $50 billion on research and development. But the path to drug approval by the Food and Drug Administration is laden with abrupt failures in late-phase testing. Only one in 5,000 drugs will make it to market, according to one estimate…Christopher Moir, a professor of pediatric surgery at the Mayo Clinic in Rochester, Minn., says he has used 3-D printing to produce plastic models of organs used to prepare for surgeries. “Bioprinting is going to be a huge aspect in terms of implants and surgeries,” Dr. Moir says.

Reach: The Wall Street Journal, a US-based newspaper published by Dow Jones & Company, has the largest print circulation in America with 1.4 million (60 percent) of a total of 2.3 million. Its website has more than 4.3 million unique visitors each month.

Hospitals are trying to make it safer for patients to go under the knife. Surgery can be risky by its very nature, and the possibility of error or negligence makes it even more so. According to an analysis last year in the journal Patient Safety in Surgery, 46% to 65% of adverse events in hospitals are related to surgery, especially complex procedures... Two studies published in early February in the Journal of the American Medical Association appeared to challenge the approach, finding that outcomes have improved in hospitals generally in recent years whether they participated in NSQIP or not. One, by researchers at the Mayo Clinic, compared billing claims data between participating and nonparticipating hospitals and found no statistically significant differences in the likelihood of complications, or death.

Reach: The Wall Street Journal, a US-based newspaper published by Dow Jones & Company, has the largest print circulation in America with 1.4 million (60 percent) of a total of 2.3 million. Its website has more than 4.3 million unique visitors each month.

Context: Mayo Clinic is one of the largest and most experienced surgical practices in the world. Mayo has more than 300 surgeons and 122 operating rooms among its three locations in Arizona, Florida and Minnesota. Mayo surgeons perform high volumes of complex operations. In 2005, Mayo Clinic surgeons treated nearly 73,000 patients using the latest technology and innovative procedures. Mayo Clinic evaluates quality by looking at outcome measures, process measures, patient satisfaction and quality rankings.

Mayo Clinic in the News is a weekly highlights summary of major media coverage. If you would like to be added to the weekly distribution list, send a note toLaura Wuotila with this subject line: SUBSCRIBE to Mayo Clinic in the News.

…The trial Boehle enrolled in is called BEAUTY, which stands for "breast cancer genome guided therapy." Launched in 2013​, it's ​​​​based at the Mayo Clinic in Rochester, Minnesota. Using avatar mice – mice with patients’ tumor samples growing inside of
them – researchers are able to study various treatments and determine which might be best tailored to each patient. “When we treat the mice with drugs, that is very much a mirror of what happens in patients,” says Judy Boughey, ​a breast surgeon at the Mayo Clinic. Boughey is a co-director of the study, which enrolled 140 breast cancer patients.

Reach: US News reaches more than 10 million unique visitors to its website each month.

Context: The Breast Cancer Genome-Guided Therapy (BEAUTY) study is designed to help researchers better understand why standard chemotherapy eradicates breast cancer in some women but fails in others. The long-term goal is to enable individualized treatment for each woman with breast cancer by using the genetic information found in blood samples and tumor biopsies to predict the most effective therapies. Judy Boughey, M.D. and Matthew Goetz, M.D. are co-chairs of the study.

Despite being declared beaten in 2000, measles is back, due largely to declining
vaccination rates in parts of the United States. "We should not be in this boat," Dr. Pritish Tosh, an infectious diseases physician and researcher at the Mayo Clinic, told The Huffington Post. "This is a completely preventable disease."

Globe and MailCould we stop the anti-vaxxers if we said measles contains gluten?

... An infectious-disease specialist armed with meticulous research makes a sober presentation. She quotes Roberto Cattaneo, a molecular biologist at the Mayo Clinic who has spent 30 years studying measles, which he calls “the most transmissible virus we know.” She leans authoritatively on the chair’s desk, and speaks to him directly. “Let me make my case to parents,” she pleads.

Circulation:The Globe and Mailis Canada’s national newspaper and has a daily circulation of more than 306,000. The Globe and Mail Online has more than 840,000 unique visitors to its website each month.

Context:Roberto Cattaneo, Ph.D. studies measles and other small enveloped RNA viruses with the primary goal of generating new knowledge.

ForbesMeasles Outbreak in Dollars and Cents: It Costs Taxpayers Bigtime

“These outbreaks have economic costs. They are disruptive,” said Gregory Poland, head of the Mayo Clinic's Vaccine Research Group. “The smaller ones have cost a couple hundred dollars in public resources, and one cost nearly a million dollars. It’s on the lesser side – health is more important – but it consumes public health resources that could be applied to the other pressing problems we face.”

Reach:Forbes magazine focuses on business and financial news with core topics that include business, technology, stock markets, personal finance, and lifestyle. The magazine is published twice each month and has more than 925,000 subscribers. Forbes Online receives more than 10.4 million unique visitors each month.

Context: Gregory Poland, M.D., studies the immunogenetics of vaccine response in adults and children. Dr. Poland and his team within the Vaccine Research Group aim to improve the health of individuals across the world by pursuing challenges posed by infectious diseases and bioterrorism through clinical, laboratory and epidemiologic vaccine research.

"We actually suffer from this liberal exemption rule," said Dr. Robert Jacobson, a pediatrician at Mayo Clinic. "We could be doing better with our vaccination rates."

Reach:Minnesota Public Radio operates 43 stations and serves virtually all of Minnesota and parts of the surrounding states. MPR has more than 100,000 members and more than 900,000 listeners each week, which is the largest audience of any regional public radio network.

Mayo Clinic in the News is a weekly highlights summary of major media coverage. If you would like to be added to the weekly distribution list, send a note toLaura Wuotila with this subject line: SUBSCRIBE to Mayo Clinic in the News.

APObama Proposes 'Precision Medicine' To End One-Size-Fits-All by Lauran Neergaard

President Barack Obama is calling for an investment to move away from one-size-fits-all-medicine, toward an approach that tailors treatment to your genes…People with a rare form of cystic fibrosis now can choose a drug designed specifically to target the genetic defect causing their illness. Some medical centers, such as the Mayo Clinic, have opened "individualized medicine clinics."

When Dustin Bennett was 18 months old, his mother realized there was something wrong with him, that he was suddenly having a hard time keeping his balance when he stood upright…Finally, at the suggestion of one of the many physicians she consulted, the Bennetts made the trip from their home in Pearson, Ga., to Jacksonville so they could consult with Mayo Clinic neurologist Zbigniew Wszolek.

Mayo Clinic has built a national research program and a national referral medical clinic to advance the benefits of these discoveries, which already are beginning to benefit patients on our Jacksonville campus. We consider precision medicine a priority and an essential part of the future of medical practice.

Obama’s proposed funding may not be enough to support the project. “I think the polite way to say it is that it’s a good start,” said Gianrico Farrugia, chief executive officer of Mayo Clinic’s Florida campus and former director of Mayo’s Center for Individualized Medicine. “It is certainly really encouraging that there is alignment between the NIH and the White House, and it kick starts the thing we need to do, but it’s an initial investment just to start things,” Farrugia said by telephone.

Reach:Bloomberg has 2,300 media professionals in 146 bureaus across 72 countries. Bloomberg delivers its content across more than 400 publications, over 310 million households worldwide through Bloomberg Television and 500,000 in the New York metro area and 18.5 million subscribers through satellite radio.

…“If we have a big data set, a big pool of people that’s varied, then that allows us to really map out not only the genome of one person, but now we can start seeing connections and patterns and correlations that helps us refine exactly what it is that we’re trying to do with respect to treatment,” the president said at a White House ceremony, attended by Mayo Vice President Dr. Gianrico Farrugia.

Reach: The Star Tribune Sunday circulation is 518,745 copies and weekday circulation is 300,277. The Star Tribune is the state’s largest newspaper and ranks 16th nationally in circulation.

Context: Individualized medicine, also known as personalized medicine or precision medicine, means tailoring diagnosis and treatment to each patient to optimize care. Patients have experienced this kind of care for 150 years at Mayo Clinic, where teams of specialists have always worked together to find answers. More information about the Mayo Clinic Center for Individualized Medicine can be found on Mayo Clinic News Network. Mayo Clinic's response to President Obama's precision medicine initiative can be found here.

Mayo Clinic in the News is a weekly highlights summary of major media coverage. If you would like to be added to the weekly distribution list, send a note toLaura Wuotila with this subject line: SUBSCRIBE to Mayo Clinic in the News.

Mayo Clinic CEO Dr. John Noseworthy discusses his priorities for 2015, patient care and technology in the U.S. and the development and cost of Hepatitis C therapies.

Reach:FoxNews.com has more than 13 million unique visitors each month. Fox Business Network is headquartered in News Corporation's studios in midtown Manhattan with bureaus in Chicago, Los Angeles, San Francisco (Silicon Valley), Washington, D.C. and London.

After nine years of epileptic seizures and no success stopping them, Sheri Finstad wasready to try an experiment. In October, she came to Rochester, where Mayo Clinic doctors implanted a device in her brain designed to deliver mild electrical pulses and record the brain's reaction… "We can see exactly what our stimulation does to the ongoing activity in the brain," said Finstad's neurologist, Dr. Matt Stead. "That will allow us ... hopefully to understand better what patterns and types of stimulation are most likely to suppress their propensity toward seizures."

Reach:Minnesota Public Radio operates 43 stations and serves virtually all of Minnesota and parts of the surrounding states. MPR has more than 100,000 members and more than 900,000 listeners each week, which is the largest audience of any regional public radio network.

"Today is Thursday, the day of Meaning." That's the message at the very top of the page. And from there down, almost everything about Amit Sood's website, stressfree.org, is couched in the self-help jargon that scientists instinctively dismiss. So it's especially interesting that Sood is a physician, a professor of medicine at the Mayo Clinic, no less.

Reach: The Atlantic was founded in 1857, produces 10 issues a year and has 1.2 million readers each month. The magazine also has a number of platforms on the web including The Atlantic, TheAtantic.com, AtlanticLIVE, Atlantic Mobile, The Atlantic Wire and The Atlantic Cities

Context: In The Mayo Clinic Guide to Stress-Free Living, Mayo Clinic stress management and resiliency expert Amit Sood, M.D., draws on decades of groundbreaking research to offer readers a scientifically proven, structured and practical approach to reducing stress. He explains the brain’s two modes — focused mode and default mode — and how an imbalance between the two produces unwanted stress, and he shares new insights about how the mind works, including its natural tendency to wander. In this easy-to-follow guide, Dr. Sood provides actionable steps to cultivate emotional and mental strength, find greater fulfillment and nurture a kind disposition. More information, including a video interview with Dr. Sood, can be found on Mayo Clinic News Network.
Public Affairs Contacts:Ginger Plumbo, Brian Kilen

… The Mayo Clinic weighed in on Tuesday, throwing its support behind the King-Devick with a first-of-its-kind licensing agreement. "Mayo Clinic certainly wouldn't endorse, support or be associated with something they didn't thoroughly vet, and this was thoroughly vetted. The data speaks for itself," said Dr. David Dodick, a neurologist who heads Mayo's Concussion Program. "Is it perfect? No, nothing is perfect," Dodick said. "But is it a valuable tool that can be used pitchside, rinkside and on the sideline to report the suspicion of a concussion? Absolutely."

Reach:USA TODAY has the highest daily circulation of any U.S. newspaper with a daily average circulation of 4.1 million, which includes print, various digital editions and other papers that use their branded content.

Context: Concussions are in the national spotlight for the damage being done to student and professional athletes. Determining when an athlete should be removed from play is a major challenge in preventing injury. Athletes routinely deny symptoms.

Mayo Clinic in the News is a weekly highlights summary of major media coverage. If you would like to be added to the weekly distribution list, send a note toLaura Wuotila with this subject line: SUBSCRIBE to Mayo Clinic in the News.

Proposed federal rules to require new government approval of certain tests developed in medical schools and private business laboratories have drawn cries of protest from the Mayo Clinic… Mayo says it already goes through a certification process with other federal agencies and monitors its so-called adverse events. The clinic recently sent the chairman of its laboratory medicine and pathology department to Washington to testify against the rules as the government considers tweaking them. “These rules have the potential to get in the way of effective patient care and really disrupt the whole patient-physician-laboratory relationship,” Dr. Curtis Hanson told the Star Tribune after his testimony to the FDA.

Reach: The Star Tribune Sunday circulation is 518,745 copies and weekday circulation is 300,277. The Star Tribune is the state’s largest newspaper and ranks 16th nationally in circulation.

Context:Curtis Hanson, M.D. is chair of Mayo Clinic laboratory medicine and pathology, one of the largest clinical laboratories in the world. It is composed of more than 3,200 people working in numerous specialty laboratories performing more than 20 million tests a year.

Broody, a very unhappy brain, is plagued by fear and self-doubt. "Seeing others in pain, physical or emotional, fires his own pain network," says Amit Sood, M.D., professor of medicine at the Mayo Clinic and chair of the Mayo Mind Body Initiative, in a new video "starring" Broody. "His imaginary fears cause him real damage."

Context: In The Mayo Clinic Guide to Stress-Free Living, Mayo Clinic stress management and resiliency expert Amit Sood, M.D., draws on decades of groundbreaking research to offer readers a scientifically proven, structured and practical approach to reducing stress. He explains the brain’s two modes — focused mode and default mode — and how an imbalance between the two produces unwanted stress, and he shares new insights about how the mind works, including its natural tendency to wander. In this easy-to-follow guide, Dr. Sood provides actionable steps to cultivate emotional and mental strength, find greater fulfillment and nurture a kind disposition. More information, including a video interview with Dr. Sood, can be found on Mayo Clinic News Network.

Walking for 20 minutes every day can reduce a person's risk of death by up to 30 percent, according to a new University of Cambridge study. Dr. Edward Laskowski, Mayo Clinic, is interviewed by Dr. Nancy Snyderman, NBC Medical Correspondent.

Washington PostWhat is President Obama’s ‘precision medicine’ plan, and how might it help you?by Lenny Bernstein

In his hour-long State of the Union address Tuesday night, President Obama spent a few seconds announcing a "Precision Medicine Initiative," but did little to explain what he has in mind…What is precision medicine? Clinically, experts don't even agree on a single term for it. But "individualized," "personalized," and "precision," medicine are all used to convey the same idea, according to Gianrico Farrugia, former director of the Mayo Clinic's Center for Individualized Medicine: "rather than treating a person as [part of] a group, treat the person as an individual, based on [his or her] own genetic material, to enable us to provide individualized, personalized and precise care."

Context: Individualized medicine, also known as personalized medicine or precision medicine, means tailoring diagnosis and treatment to each patient to optimize care. Patients have experienced this kind of care for 150 years at Mayo Clinic, where teams of specialists have always worked together to find answers. More information about the Mayo Clinic Center for Individualized Medicine can be found on Mayo Clinic News Network. Mayo Clinic's response to President Obama's precision medicine initiative can be found here.

Mayo Clinic in the News is a weekly highlights summary of major media coverage. If you would like to be added to the weekly distribution list, send a note toLaura Wuotila with this subject line: SUBSCRIBE to Mayo Clinic in the News.

…An adult with a BMI of 30 or higher is considered obese, according to the Centers for Disease Control and Prevention. An adult with a BMI between 25 and 29.9 is considered overweight. "This study adds to the mounting evidence that movement and activity makes a difference in your health, even if you are not at your ideal weight," said Dr. Edward Laskowski, a professor in the department of physical medicine and rehabilitation at the Mayo Clinic, and co-director of the Mayo Clinic Sports Medicine Center.

Reach: The TODAY Show reaches an average daily audience of 4.25 million viewers each week. Today Health is the online portal of the Today Show.

Cancer biopsies do not cause the disease to spread, says a new study that dispels a common myth. "This study shows that physicians and patients should feel reassured that a biopsy is very safe," said study senior investigator Dr. Michael Wallace, a gastroenterologist and professor of medicine at the Mayo Clinic in Jacksonville, Fla.

Reach:HealthDay distributes its health news to media outlets several times each day and also posts its news on its website, which receives more than 39,000 unique visitors each month.

WEAU Eau ClaireHalf Moon Dragon Boat Festival in Eau Claire to benefit hospiceHow do you tame a dragon? You can't do it without a paddle. At least, that's according to Mayo Clinic Health System. The Half Moon Dragon Boat Festival is coming to Eau Claire on Saturday, August 8th, 2015 at Half Moon Beach. Proceeds will help families dealing with the loss of loved ones through hospice care.… John Dickey is the Chief Administrative Officer of Mayo Clinic Health System's northwest region. He said the event will raise awareness of hospice care for people in the final stages of life.

Reach: WEAU-TVis the NBC affiliate for much of western Wisconsin, including Eau Claire and La Crosse.

Context: Mayo Clinic Health System is sponsoring its inaugural Half Moon Dragon Boat Festival on Saturday, Aug. 8, to raise awareness for hospice care for people at the end of their life. Funds raised will support a bereavement program for families and all community members following the loss of a loved one. For more information, visit mayoclinichealthsystem.org/halfmoondragon.

KPHO PhoenixFree help offered to free yourself from cancer by Juan Magana. The Mayo Clinic wrapped up a weekend-long event in north Phoenix to help patients and family members, who are currently fighting cancer or have been cured, deal with the emotional rollercoaster. The Living With and Overcoming My Cancer Symposium brought out cancer experts to answer questions people had. "We're thrilled to put this on and to give them a sense of community," said Dr. Ruben Mesa, the director of the Mayo Cancer Clinic. "

Context:Ruben Mesa, M.D., is a chair of Hematology/Oncology at Mayo Clinic in Arizona. The Mayo Clinic Cancer Center is a National Cancer Institute-designated comprehensive cancer center with a multisite presence. Its three campuses — in Scottsdale, Ariz., Jacksonville, Fla., and Rochester, Minn. — give the Mayo Clinic Cancer Center a broad geographic reach, enabling it to serve diverse patient populations around the world. Eunice Nishimura is a Mayo Clinic patient and is a a stage 4 lung cancer survivor. You can read more about her cancer journey on Sharing Mayo Clinic.

Mayo Clinic has named Dr. John Presutti as chief executive officer of Mayo Clinic Health System in Waycross, effective March 2, 2015. Presutti succeeds Kenneth Calamia, who will retire from Mayo Clinic at the end of 2015.

Yahoo! HealthGot The Flu? Here's When To Head To The ER… It’s important to be aware of what can happen if an illness progresses, according to a new overview in the journal Mayo Clinic Proceedings. In the piece, senior author Steve Peters, M.D., a pulmonary and critical care doctor at the Mayo Clinic, says that deadly sepsis is a very real risk in infections such as the flu. We caught up with him for a download on sepsis and other common flu complications — and when to get yourself or a loved one to the ER, stat.

Reach: Yahoo! reaches more than a half a billion across devices and around the globe. According to news sources roughly 700 million people visit Yahoo websites every month.

Mayo Clinic in the News is a weekly highlights summary of major media coverage. If you would like to be added to the weekly distribution list, send a note toLaura Wuotila with this subject line: SUBSCRIBE to Mayo Clinic in the News.

We asked the 153 members of the Wall Street Journal’s CEO Council to tell us whether they’re positive or negative about business prospects in 2015, and why. Here’s what several had to say:…John Noseworthy, Mayo Clinic, Disruptive technologies – ranging from regenerative and genomic medicine to remote monitoring devices – have already begun to alter health care delivery. We’re excited to work with diverse business partners to quickly commercialize these and other novel scientific discoveries so they benefit patients everywhere.

Reach: The Wall Street Journal, a US-based newspaper published by Dow Jones & Company, is second in newspaper circulation in America with an average circulation of 223 million copies on week days. Its website has more than 4.3 million unique visitors each month.

It is a parenting milestone that seems to take place overnight: Your child is suddenly taller than you… Children are reaching their adult height at younger ages, however, says Siobhan Pittock, a pediatric endocrinologist at the Mayo Clinic Children’s Center in Rochester, Minn. She cites a gradual trend toward puberty starting a few months earlier, causing children to start their growth spurt earlier… Eric Sorenson’s son Tom rocketed past him in a matter of weeks, says Tom’s mother, Kristin, of Rochester, Minn. They noticed the shift when looking at a couple of family photos taken two months apart, when Tom was 14. In the first, Tom appears about 2 inches shorter than his 5-foot-9 dad.

Reach: The Wall Street Journal, a US-based newspaper published by Dow Jones & Company, is second in newspaper circulation in America with an average circulation of 223 million copies on week days. Its website has more than 4.3 million unique visitors each month.

Related Coverage:Wall Street Journal, The 10-Point. A personal, guided tour to the best scoops and stories every day in The Wall Street Journal, from Editor in Chief Gerard Baker.A Tall Tale. It’s a strange thing to look up to your child. Our Work & Family columnist Sue Shellenbarger writes about a milestone that in many households seems to take place overnight: when a child grows taller than mom and dad. Adults’ height hasn’t changed much in recent years, but a pediatric endocrinologist at the Mayo Clinic Children’s Center says children are reaching their grown-up height at younger ages.

…Dr. John Noseworthy, CEO, Mayo Clinic. In 2014, the Mayo Clinic set in motion a 20-year, $6 billion economic development project in its hometown of Rochester. The goal is to enhance Mayo’s status as a global destination for health care, while growing the local economy.

Reach: The Star Tribune Sunday circulation is 518,745 copies and weekday circulation is 300,277. The Star Tribune is the state’s largest newspaper and ranks 16th nationally in circulation.

The 20-year plan for the Destination Medical Center lays out the steps toward a global center for health and wellness…A global destination for health care and wellness. This is the vision of the Destination Medical Center (DMC) initiative — a vision that is now one step closer to becoming reality with the completion of the comprehensive draft development plan on Dec. 17.

Reach: The Star Tribune Sunday circulation is 518,745 copies and weekday circulation is 300,277. The Star Tribune is the state’s largest newspaper and ranks 16th nationally in circulation.

Related Coverage:KARE11 (AP), Rochester businesses closing amid Mayo plan. The face of downtown Rochester is changing as the city remakes itself amid Mayo Clinic's development of its massive Destination Medical Center. Minnesota Public Radio News reports several longstanding businesses will soon close due to the rising cost of commercial downtown space. The effects of the 20-year plan to cement Mayo as a global health care destination have prompted concerns from residents who want to ensure Rochester doesn't simply become a city for nonlocals.

Context: The development plan proposed at the DMCC Board meeting Dec. 17 is a BIG PLAN (694 pages) in support of a bold vision. And what everyone wants to know is: What’s going to happen and how much will it cost? More information can be found on the DMC blog.

In a 100-year-old home in Rochester, originally built for one of Mayo Clinic's first surgeons, is where Alyssa Sandeen spent 5 months of her life. We first told you about Sandeen in the summer of 2013, not long after she got her second heart transplant. She got her first at age 8 in 1998, a heart that lasted 15 years – but barely.

It was a big summer for Mayo Clinic Health System and the city of Cannon Falls, which celebrated the opening of a new 92,000-square-foot medical center off Goodhue County Road 24. “The new facility has allowed us to serve our patients better in many ways,” said Bill Priest, operations administrator.

Reach: The Red Wing Republican Eagle, which is published twice each week and has a circulation of more than 5,400, has served residents of Red Wing, Minn., since 1857.

Mayo Clinic in the News is a weekly highlights summary of major media coverage. If you would like to be added to the weekly distribution list, send a note toLaura Wuotila with this subject line: SUBSCRIBE to Mayo Clinic in the News.

This will be our last installment of our weekly highlights in 2014. We'll be back in early January 2015. Happy Holidays.

That noise coming from your knees can be unnerving. But unless it is accompanied by pain, discomfort or swelling, there is no need to worry about it, said Dr. Michael Stuart, a professor of orthopedic surgery and co-director of sports medicine at the Mayo Clinic.

Reach:The New York Times has a daily circulation of more than 735,000. Its website receives more than 16.2 million unique visitors each month.

John Noseworthy, president and CEO of Mayo Clinic, joins The Daily Circuit to talk about the future of Mayo, the future of health care and how the two intersect.

Reach:Minnesota Public Radio operates 43 stations and serves virtually all of Minnesota and parts of the surrounding states. MPR has more than 100,000 members and more than 900,000 listeners each week, which is the largest audience of any regional public radio network.

In 2007, Mayo Clinic approached Dr. John Noseworthy (MD’75, PGM’78), then medical director of its Department of Development, and a team of leaders with a question: what would the world’s largest, integrated, nonprofit medical group look like in the year 2020? “We spent almost a year looking into that,” recalls Dr. Noseworthy. “We came back and said Mayo Clinic is known for caring for the sick face-to-face – for patients coming to us. As we enter a digital world, how are we going to extend our reach to serve people who do not need, or cannot come, to see us?”

When planners of Minnesota's largest economic development project unveil a final draft this afternoon of the city's massive expansion project, they will present a new vision for downtown city life. The $6 billion Destination Medical Center aims to make Rochester a global health care hub. But it also would make big changes to the city, among them.

Reach:Minnesota Public Radio operates 43 stations and serves virtually all of Minnesota and parts of the surrounding states. MPR has more than 100,000 members and more than 900,000 listeners each week, which is the largest audience of any regional public radio network.

Context: The development plan proposed at the DMCC Board meeting Dec. 17 is a BIG PLAN (694 pages) in support of a bold vision. And what everyone wants to know is: What’s going to happen and how much will it cost? More information can be found on the DMC blog.

Mayo Clinic has appointed an attorney,Christina Zorn, as chief administrative officer and vice chair of administration at Mayo's Jacksonville campus. She will serve as administrative partner to Gianrico Farrugia, M.D., the incoming vice president of Mayo Clinic and CEO of the Jacksonville campus, according to a news release. Zorn begins work Jan. 1.

Context: Mayo Clinic recently appointed Christina Zorn, J.D., as chief administrative officer of its campus in Jacksonville, Fla., and vice chair of Administration, Mayo Clinic. She will serve as administrative partner to Gianrico Farrugia, M.D., incoming vice president of Mayo Clinic and chief executive officer of the Jacksonville campus, as previously announced. Zorn assumes her new role on Jan. 1. More information can be found on Mayo Clinic News Network.

Mayo Clinic in the News is a weekly highlights summary of major media coverage. If you would like to be added to the weekly distribution list, send a note toLaura Wuotila with this subject line: SUBSCRIBE to Mayo Clinic in the News.

Reach: The Wall Street Journal, a US-based newspaper published by Dow Jones & Company, is second in newspaper circulation in America with an average circulation of 223 million copies on week days. Its website has more than 4.3 million unique visitors each month.

Jordan Hatfield’s case puzzled the doctors. A champion javelin thrower and top student at Northern Kentucky University, Hatfield developed stomach pains and insomnia during his sophomore year. Then came headaches, vision problems and nerve pain...Hatfield is among dozens of patients in Kentucky to benefit from the Mayo Clinic Care Network, an ambitious effort by the Rochester-based health system to expand its reach and secure its place in an era of rapid changes in health care. In just four years, Mayo has signed up 31 affiliates in 18 states, Mexico and Puerto Rico.

The patients arrive at the Mayo Clinic from all over the world, thousands a day, each presenting a different medical challenge. Some have illnesses so rare that even medical journals don’t offer a time-tested treatment plan. Others bring a complicated combination of ailments — diabetes with heart failure and kidney disease — that offer conflicting treatment options… “What we’re trying to find out, if we can, is what does health care cost, and what of that spend really adds value to a patient’s outcome over time, especially with these high-impact diseases,” said Mayo Clinic CEO Dr. John Noseworthy. Additional stories: ‘Big data’ is changing American medical care, Timeline: A look back at key events in the history of the Mayo Clinic

Tony Luebbers was one of the first patients in which his hometown doctors at St. Elizabeth Healthcare could work hand-in-hand with the Mayo Clinic in Rochester. It turned out to be one for the medical books. Luebbers, a retired accountant, had gone to see his family doctor in this northern Kentucky city complaining of stomach pains. Multiple screenings and biopsies left doctors baffled. Through St. Elizabeth’s affiliation with the Mayo Clinic Care Network, Luebbers’ Kentucky doctors were able to share lab results and medical records, and consult directly with Mayo’s deep bench of experts.

Reach: The Star Tribune Sunday circulation is 518,745 copies and weekday circulation is 300,277. The Star Tribune is the state’s largest newspaper and ranks 16th nationally in circulation.

Context: The Next Mayo is a Star Tribune series examining Minnesota's legendary clinic in a competitive era for health care.

The phone rang, and all Tess Pfohl could do was pray. It was the day before Thanksgiving, about three months since the 25-year-old Cannon Falls native had undergone 20 hours of surgery to remove a potentially fatal cancer that had wrapped itself around her spine. Pfohl had voluntarily chosen to become paraplegic in hopes of extending her life, but Mayo Clinic doctors were unwilling to discuss her chances of survival. Mayo Clinic surgeon Dr. Michael Yaszemski said the world-class facility has performed just 160 such surgeries in the past 18 years…Pfohl, who normally is an avid social media user, went silent during the wait. She returned only after breathing a sigh of relief when the Mayo Clinic called to report the spot wasn't cancerous.

Reach: The Post-Bulletin has a weekend readership of nearly 45,000 people and daily readership of more than 41,000 people. The newspaper serves Rochester, Minn. and southeast Minnesota.

Context:Michael Yaszemski, M.D. is a Mayo Clinic orthopedic surgeon. Dr. Yaszemski investigates bone, cartilage and spinal cord regeneration using synthetic polymeric scaffolds, cells and controlled delivery of bioactive molecules. Dr. Yaszemski's Tissue Engineering and Biomaterials Laboratory is equipped to perform polymer synthesis and characterization and scaffold fabrication utilizing injectable techniques and solid freeform fabrication techniques. His research team cultures cell-polymer constructs, studies delivery kinetics of bioactive molecules from microparticles and microparticle-scaffold combinations, and studies these scaffold-cell-biomolecule combinations in vivo. The team investigates musculoskeletal sarcoma biology and works on the controlled local delivery of chemotherapeutic agents to osteosarcoma, chordoma and chrondrosarcoma.

Mayo Clinic in the News is a weekly highlights summary of major media coverage. If you would like to be added to the weekly distribution list, send a note toLaura Wuotila with this subject line: SUBSCRIBE to Mayo Clinic in the News.

Charlie Rose (PBS)John Noseworthy, President and CEO of the Mayo Clinic in Rochester, Minnesota (24-minute interview)

John Noseworthy, M.D., president and CEO, Mayo Clinic, was interviewed in New York City on Dec. 1 by Charlie Rose, host of his nationally distributed PBS show since the early 1990s. Dr. Noseworthy was interviewed about Mayo Clinic and as a thought leader on health care in the U.S. The in-depth interview covered a range of many topics from Mayo's history to the future of health care.

Reach: Charlie Rose engages America's best thinkers, writers, politicians, athletes, entertainers, business leaders, scientists and other newsmakers in one-on-one interviews and roundtable discussions. The program is taped at Bloomberg LP's headquarters in New York City and airs on PBS stations across the U.S. as well as during evening hours on Bloomberg Television around the world. Charlie Rose also co-anchors "CBS This Morning" and is a contributing correspondent to “60 Minutes.”

On “Charlie Rose,” a conversation with John Noseworthy, the President and CEO of Mayo Clinic in Rochester, Minnesota. (U.S. News & World Report named Mayo Clinic the best hospital in the nation this year.)

Reach: Charlie Rose engages America's best thinkers, writers, politicians, athletes, entertainers, business leaders, scientists and other newsmakers in one-on-one interviews and roundtable discussions. The program is taped at Bloomberg LP's headquarters in New York City and airs on PBS stations across the U.S. as well as during evening hours on Bloomberg Television around the world. Charlie Rose also co-anchors "CBS This Morning" and is a contributing correspondent to “60 Minutes.”

FOX BusinessMayo Clinic CEO talks health care innovationMayo Clinic CEO Dr. John Noseworthy discusses how innovation is being used to get ahead of disease and the Affordable Care Act’s impact.

Reach:FoxNews.com has more than 13 million unique visitors each month. Fox Business Network is headquartered in News Corporation's studios in midtown Manhattan with bureaus in Chicago, Los Angeles, San Francisco (Silicon Valley), Washington, D.C. and London.

Mayo Clinic is seemingly everywhere. Over the past few years Mayo has built up a network of 29 affiliated hospitals in 18 states (plus hospitals in Mexico and Puerto Rico). These hospitals use the Mayo brand and can tap into Mayo resources but are not owned by the Minnesota health system… "When we look at health care in this country, we are at a crossroads in terms of what's going to happen — the industry is changing quickly," said Mayo CEO Dr. John Noseworthy.

Additional Coverage:Minneapolis/ St. Paul Business Journal, Mayo Clinic, Johns Hopkins take different paths to out-of-state growth by Katharine Grayson, Mayo Clinic and Johns Hopkins each view forging partnerships with out-of-state hospitals as a growth strategy, but the big-name international health care brands are taking different approaches to expand their reach.

Post-Bulletin, Heard on the Street: Johns Hopkins takes different strategy by Mike Klein. Johns Hopkins, the Baltimore-based health-care giant that's a nationwide competitor of Mayo Clinic, is taking a different route toward expansion.

Florida Times-UnionMayo Clinic study finds many people who think they are allergic to penicillin are notby Charlie Patton

When Lisa Dickelman-Foster was 16, she was given penicillin to treat her mononucleosis. She went into anaphylactic shock, a life-threatening condition…He urged Dickelman-Foster, who works as a nurse at the Mayo Clinic’s hospital in Jacksonville, to get tested to see if she was still allergic to penicillin. Thanai Pongdee, a specialist in allergy/immunology with the Mayo Clinic, tested her and found that she was no longer allergic.

Context:Thanai Pongdee, M.D. is an allergy and immunology expert at Mayo Clinic's campus in Jacksonville, Florida. Physicians in the Division of Allergy see patients with immunologic and allergic disorders. Their goal is to provide patients with comprehensive evaluations, diagnosis, treatment and education about allergic conditions.

There has been a lot of buzz about “big data” over the last few years. This is hardly surprising, given the sheer scale of the data sets that are being produced daily. A total of 2.5 quintillion terabytes of data were generated every day in 2012 alone, and it is estimated that as much data is now generated in just two days as was created from the dawn of civilization until 2003. While other industries have been far more successful at harnessing the value from large-scale integration and analysis of big data, health care is just getting its feet wet. Yes, providers and payers are increasingly investing in their analytical capabilities to help them make better sense of the changing health care environment, but it is still early days. Here are some key elements that are crucial for health care to truly capture the value of big data.

Reach:Harvard Business Review – Online provides editorial content designed to complement the coverage found in its parent print publication, which focuses on business management. The site receives more than 232,000 unique visitors each month.

The director of the Mayo Clinic Center for Regenerative Medicine has received the American Heart Association's 2014 Basic Research Prize. An auditorium filed with thousands of researchers honored Dr. Andre Terzic at the 2014 American Heart Association Scientific Sessions in Chicago as the group's sole annual recipient.

Reach: The Post-Bulletin has a weekend readership of nearly 45,000 people and daily readership of more than 41,000 people. The newspaper serves Rochester, Minn. and southeast Minnesota.

Context: The American Heart Association (AHA) awarded the 2014 Basic Research Prize to Andre Terzic, M.D., Ph.D., of Mayo Clinic. The award, presented at the annual meeting of the American Heart Association in Chicago, recognizes outstanding contributions to the advancement of cardiovascular science. Dr. Terzic was commended for pioneering applications of emerging technologies to advance the diagnosis and treatment of cardiovascular diseases. “In the year when we celebrate the 100th anniversary of the Division of Cardiovascular Diseases at Mayo Clinic, we are particularly proud that one of our own has been recognized with such a prestigious national award,” says Charanjit Rihal, M.D., chair of Mayo's Division of Cardiovascular Diseases. “Dr. Terzic has truly advanced the frontiers of medical science. As a pioneer in cardiac regenerative medicine, he and his team have been at the vanguard of health care.” More information can be found on Mayo Clinic News Network.