DrugBank target: P35367

(
There is one structure corresponding to this UniProt sequence
in the PDB.
)

Histamine H1 receptor

H1R,
HH1R.

Function

In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system..