Following the events of Age of Ultron, the collective governments of the world pass an act designed to regulate all superhuman activity. This polarizes opinion amongst the Avengers, causing two factions to side with Iron Man or Captain America, which causes an epic battle between former allies.

Four friends fleeing a viral pandemic soon learn they are more dangerous than any virus.A deadly virus has spread across the globe. Contagion is everywhere, no one is safe and no one can be trusted. Four young attractive people race through the back roads of the American West to the pounding beat of a vacation soundtrack. Their aim is to retreat to secluded utopian beach in the Gulf of Mexico, where they could peacefully wait out the pandemic and survive the apocalyptic disease. Their plans take a grim turn when their car breaks down on an isolated road starting a chain of events that will seal the fate of each of them in an inexorable and horrifying voyage of hell through a western landscape populated by only the hideous dead or the twisted living.

After the cataclysmic events in New York with The Avengers, Steve Rogers, aka Captain America is living quietly in Washington, D.C. and trying to adjust to the modern world. But when a S.H.I.E.L.D. colleague comes under attack, Steve becomes embroiled in a web of intrigue that threatens to put the world at risk. Joining forces with the Black Widow, Captain America struggles to expose the ever-widening conspiracy while fighting off professional assassins sent to silence him at every turn. When the full scope of the villainous plot is revealed, Captain America and the Black Widow enlist the help of a new ally, the Falcon. However, they soon find themselves up against an unexpected and formidable enemy—the Winter Soldier.