Knollwood Partners, LLC was formed in 2003 by Frank S. Castellana, M.D., Eng.Sc.D. and James G. Ham, M.B.A. Dr. Castellana and Mr. Ham each have over twenty-five years of senior management experience in the pharmaceutical and medical products industries.

Dr. Castellana was a senior executive at Bristol-Myers Squibb, where he held various positions of increasing responsibility in the Pharmaceutical and Medical Device Divisions, including Vice President of Franchise Development and Strategic Planning in the Worldwide Medicines Group, Senior Vice-President Science and Technology and President Infection and Contamination Control at the ConvaTec Division, and Director of Medical and Regulatory Affairs at Squibb Diagnostics. Prior to joining Bristol-Myers, he was Associate Professor of Chemical and Bioengineering at Columbia University, and Director of the Biomedical Engineering Center at St. Lukeís Hospital Center. Dr. Castellana received his M.D. from the Albert Einstein College of Medicine and his Eng.Sc.D. in Chemical Engineering from Columbia University.

James G. Ham, M.B.A.Partner, Knollwood Partners, LLC.

Mr. Ham was VP Finance/CFO for Clearview Projects, a consulting company which provided business development / licensing support to the biotech and pharmaceutical industries. At Clearview, Jim was responsible for the financial analysis/valuation support for all deal activities and also General Accounting, HR and IT. Prior to joining Clearview, Jim was a senior executive at Bristol-Myers Squibb and spent 24 years in various positions of increasing responsibility, principally in Finance and IT, including Vice President IT Global Business Services and Senior Director Finance for the US Pharmaceutical Group.

Andrea McGrutherDirector, Market Research, Knollwood Partners, LLC.

Having worked in the market research industry for close to 30 years, Andrea has extensive experience in both qualitative and quantitative research, and in a broad range of methodologies and analytic techniques. During the span of her career, which includes research management positions at Opinion Research Corporation and Total Research Corporation (now Harris Interactive), and others, she has held responsibility for virtually all aspects of the market research process. She has gained particular expertise and recognition for qualitative and quantitative data analysis, and while at TRC, she led a Process Improvement Team whose mission was to evaluate and improve the analysis process and enhance the value of deliverables to clients. A partial list of therapeutic areas in which Andrea has expertise includes: Respiratory Disease (COPD, asthma), mental Illness (depression, schizophrenia), cardiovascular disease (high cholesterol, hypertension, heart disease), Alzheimerís Disease, Womenís Health (osteoporosis, HRT), Menís Health (erectile dysfunction), Diabetes, Arthritis, and Migraine. Andreaís experience also includes market research concerning managed care and formulary issues, product concept testing, tracking message communication in product detail efforts and DTC advertising, image and customer satisfaction research, domestic and international research, multivariate techniques such as segmentation, PLS, conjoint analysis and discrete choice.