Odorizzi made 7 appearances for Tampa Bay in 2013, including 4 starts, and went 0-1, 3.94. He spent the bulk of the year with the AAA Durham Bulls, for whom he went 9-6, 3.33 in 22 starts. He struck out 124 opponents in 124 1/3 innings in the International League. He then made the Rays' starting rotation out of spring training in 2014. In his first outing of the year on April 4th, he defeated the Texas Rangers, 8-1, for his first major league win.