BOSTON (AP) -- Homers ended the Boston's five-game winning streak, one day after the Red Sox tied a major league record by hitting four in a row.

Frank Thomas hit his 490th homer, a go-ahead, two-run drive off Tim Wakefield in the sixth inning that led Toronto to a 7-3 victory Monday night over a Red Sox team that lacked the power and passion that produced a three-game sweep of the New York Yankees.

"It just seemed like it was a lethargic day," Boston's Doug Mirabelli said. "There wasn't the energy that we've had."

Boston reliever Mike Timlin disagreed that the 7-6 win over the Yankees on Sunday night contributed to a letdown.

"To me, that's just an excuse," he said. "We just got beat."

Aaron Hill had four hits, including a two-run homer in the ninth off Timlin, as Toronto ended a five-game losing streak. Hill has four homers in 19 games after getting six in 155 last year.

"It was good to go out and get everything right," he said. "It's good to see the Big Man hitting his homers. It got us going."

Tomo Ohka (1-2) allowed three runs -- two earned -- and six hits in five-plus innings to win in a rematch with Wakefield of Boston's 4-1 victory at Toronto last Wednesday. It was his first win in eight starts since Aug. 24 at Colorado.

Jason Frasor, filling in for injured closer B.J. Ryan, got his second save. Ryan was moved from the 15-day to the 60-day disabled list Monday,

"It's not going to be easy" without Ryan, Toronto manager John Gibbons said, "but you've got to do it."

Wakefield (2-2) gave up four runs -- three earned -- and eight hits in six innings. His ERA rose from an AL-best 1.35 to 2.08.

"I guess the wind was blowing out pretty good, but it didn't help those balls. Those balls were hit pretty good," Gibbons said.

Thomas' homer gave Toronto a 3-2 lead.

"He smoked that thing," Gibbons said.

With Vernon Wells at first and a threat to steal, Wakefield rushed his delivery.

"I just left the ball up," Wakefield said. "That's probably the turning point."

Thomas is three homers behind Lou Gehrig and Fred McGriff, who are tied for 21st, and 10 away from 500.

"That's always been a goal of mine," said Thomas, who is hitting just .232 with three homers in his first season with Toronto. "There's 10 more to go, but that's a long way to go. I don't want to be done after this year, though."

Lowell went 2-for-3 to improve his batting average to .323 but the third baseman continued his struggles in the field. His error in the second was his sixth in 36 chances. He has just six errors all last season when he had 462 chances and was second in AL fielding percentage to Oakland's Eric Chavez.

Dustin Pedroia, 1-for-28 before getting two hits Sunday, put Boston ahead 2-1 with a two-run double in the fourth. Wakefield allowed just four runs in 25 innings entering the sixth, when he gave up Thomas' second homer against the Red Sox this season and Jason Phillips' RBI single.

Boston cut the lead to 4-3 when Lowell scored on shortstop Royce Clayton's throwing error in the sixth. Adam Lind hit a sacrifice fly in the eighth.

Game notes

Boston CF Wily Mo Pena struck out in five straight at-bats before hitting into a forceout in the fourth. ... John McDonald had three hits for Toronto. ... Boston's Julio Lugo went 0-for-5 and is in a 2-for-23 slump. ... Mirabelli, the personal catcher for knuckleballer Wakefield, had his third straight two-hit game.