Artificial insemination is a technique that has some risks but all these can generally be controlled. Infection and allergic reactions to the components of the semen are rare complications.

With this type of insemination, the risk of miscarriage is about 15% and the risk of extrauterine or ectopic pregnancy (embryo implanted outside the uterus) is about 1%.

There is no scientific evidence of possible secondary long term effects on the woman's health following ovulation stimulation treatments. However, there are two major short-term risks: the most common is a multiple pregnancy (15-20%); the least common is over-stimulation or ovarian hyperstimulation (1%). The controls of the number and size of the follicles and the estradiol levels during ovulation help to identify cycles with a greater risk of hyperstimulation and multiple pregnancy and which cycles should be cancelled, evaluating each case individually.

Once a pregnancy is achieved, the possible risks for the mother or foetus are the same as those occurring with a spontaneous pregnancy, except in the case of complications occurring due to a possible multiple pregnancy, such as prematurity and low birth weight.