Sickle Erythrocytes Share this page

The strange shape and poor deformability of the sickled erythrocyte (RBC) have for the most part been considered in charge of the microvascular impediments of sickle cell disease. On the other hand, there is no relationship between the clinical seriousness of this sickness and the vicinity of sickled RBC.

Sickle cell disease is a disorder that affects the red blood cells, which use a protein called hemoglobin to transport oxygen from the lungs to the rest of the body. Normally, red blood cells are round and flexible so they can travel freely through the narrow blood vessels.