Application Information: ATP6V0A2 antibody [N2C1], Internal

Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.

Predicted Target Size

98 kDa (note)

Positive Controls

3xFlag-human ATP6V0A2-transfected 293T

Form Supplied

Liquid

Concentration

1
mg/ml
(Please refer to the vial label for the specific concentration)

Purification

Purified by antigen-affinity chromatography.

Specifications: ATP6V0A2 antibody [N2C1], Internal

Full Name

ATPase, H+ transporting, lysosomal V0 subunit a2

Background

The multisubunit vacuolar-type proton pump (H(+)-ATPase or V-ATPase) is essential for acidification of diverse cellular components, including endosomes, lysosomes, clathrin-coated vesicles, secretory vesicles, and chromaffin granules, and it is found at high density in the plasma membrane of certain specialized cells. H(+)-ATPases are comprised of a peripheral V(1) domain and an integral membrane V(0) domain; ATP6V0A2 is a component of the V(0) domain (Smith et al., 2003 [PubMed 14580332]).[supplied by OMIM]