Molecular Genetics eNews

February 2019 edition

We’d like to share an update we’ve made to our custom NGS panels offering which is now available with SureSample™ giving you a set of single nucleotide polymorphisms (SNPs) to add to your custom NGS panel; helping you in your sample identification - read on and find out more.

You’ll also find some handy hints and tips for using our CytoSure™ Interpret Software in our ever-popular video series developed by our technical specialist, Peter Gray.

Blog - Don’t Amplify the Noise

In our new Blog, Dave Cook, Senior Manager, Regional Marketing at OGT compares the pros and cons of amplicon-based and hybridisation-based sequencing strategies.

He illustrates how the latter approach overcomes many of the issues of the former, especially with respect to the difficulty of assessing the true complexity of the library and ensuring good coverage uniformity.

Presented at AMP 2018, this poster demonstrates how the superior uniformity of coverage of the hybridisation-based approach of the SureSeq protocol in combination with a SureSeq myPanel NGS Custom panel reliably detects somatic BCR-ABL1 translocations with different breakpoint locations down to a 5% frequency.