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BBC Radio 4's hostless chat show.Chain Reaction is the talk show with a twist where one week's interviewee becomes the next week's interviewer. John Cleese was first in the hot seat back in 1991 and since then, a procession of big names from the world of comedy and entertainment including Jennifer Saunders, Frank Skinner, Jarvis Cocker, Ian Hislop and Eddie Izzard have helped continue the chain.Producer: Richard MorrisA BBC Studios Production.