There's no date stamp on when the term Guido came into play, but Tricarico theorizes that it very well may have originated as an insult from within the Italian-American community, confering inferior status on immigrants who are "just off the boat."

However, the personal comments that Guido is levelling at Brown are examples of outright discrimination, and are unhelpful in the context of the ongoing disability activism in society, which is trying to improve the conditions and decrease the level of discrimination of disabled people in society.