On the occasion of the 150th Anniversary of the Italian Unification, the discovery of some letters by Giuseppe Garibaldi – referring to a period of thermal treatments at the Baths in Civitavecchia (Rome) – gave us the opportunity for writing a commentary about a not well known experience in the Two World Hero’s life: the numerous treatments carried out at many Italian spa centres for treating a rheumatic pathology (probably a rheumatoid polyarthritis) and the outcomes of various war wounds, especially the famous gunshot-wound in his right ankle during the Battle of Aspromonte, in 1862.