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Examples

Proceedings of the National Academy of Sciences, U.S.A., help to explain how epimorphic regeneration - the regrowing of morphologically and functionally perfect copies of amputated limbs - is controlled, an important step toward understanding why certain animals can do it and we cannot.

Proceedings of the National Academy of Sciences, U.S.A., help to explain how epimorphic regeneration-the regrowing of morphologically and functionally perfect copies of amputated limbs-is controlled, an important step toward understanding why certain animals can do it and we cannot.

Using a combination of pharmaceutical and genetic tools, we show that during epimorphic regeneration, expression of sdf1, as well as of its cognate receptors, cxcr4a, cxcr4b and cxcr7 are controlled by FGF signalling.