a person who is promiscuous with both sex and drugs to an annoying and overplayed degree. this person will take anything (drug) if it's free and in the company of fe/males s/he finds appealing. widely known for the combination of drugs and sex either using one to get the other or being given drugs for sex.

i got an eightball and i'm horny; think i'll call up that drugslut buffy and have her pick up a 6pack on her way over.

one who is a slut and is slut and is always high on anything from coke to motion sickness pills
ususally distastefully dressed to gain attention from males or females because if he or she were to not dress slutty then their sex life would be their hand.

dude i was at this party and this chick was thizzed out doin lines topless
what a drug slut