She has conducted research involving hundreds of companies and public agencies that have adopted "gender identity" policies. She publishes a popular blog on the subject of Transgender Workplace Diversity, and has numerous research publications on the subject of gender identity. Links to these are found below.

Dr. Weiss is a major trans voice as a contributor to a number of LGBT blogs, such as the Bilerico Project, and has done a great deal of important work towards motivating the LGBT community to lobby for the federal Employment Non Discrimination Act (ENDA).

Dr. Weiss is also Principal Consultant for Jillian T. Weiss & Associates, a consulting firm that works with organizations on transgender workplace diversity issues. She has trained hundreds of employees at corporations, law firms, universities and governmental organizations, including Harvard University, Boeing, HSBC, KPMG, Viacom, and the New York City Department of Homeless Services. Her work has been featured in news stories by the New York Times, Associated Press, Fortune Small Business Magazine, the Society for Human Resource Management, Workforce Management Magazine, and HR Executive Magazine, which may be viewed below.