In this paper, TLR20, so far with unknown function in teleost fish, has been studied in two closely related fish species, zebrafish and common carp, indicating a role in the immune response to protozoan parasites has been indicated.

Accessory molecules for Toll-like receptors in Teleost fish

This paper discusses the presence and conservation of accessory proteins, important for the biosynthesis and activation of TLR molecules in zebrafish and in common carp, thus may help refine studies on the biological activity of TLRs in fish.

Real-time imaging and genetic dissection of host–microbe interactions in zebrafish

This review describes new insights in the processes of host defence mechanisms, such as the innate immune recognition , myeloid defence mechanisms, immunometabolism and the autophagic destruction machinery, that are predicted to be relevant for biomedical research.

Stabilization of Hif-1α as a potential target for therapeutic intervention against tuberculosis.

In this paper we show that in vivo manipulation of a host-signaling pathway aids the host in combatting mycobacteria infection, identifying hypoxic signaling as a potential target for future therapeutics against TB.

MicroRNA expression during bacterial infection in zebrafish

In this paper we identify infection-inducible microRNA families that are conserved between zebrafish and human and show that one of these, the miR-146 family, affects apolipoprotein gene expression during infection.

In this article detailed protocols are presented for the robotic injection of zebrafish embryos at very high accuracy and speed opening up new avenues for the use of zebrafish larvae for large compound screens in the search for new medicines.

Pathogen Recognition and Activation of the Innate Immune Response in Zebrafish

In this review article we give an overview of the pattern recognition receptors that identify invading microbes and describe the innate immune effector mechanisms that they activate in zebrafish embryos.