The amoeba can enter through the nose into the brain. According to the Centers for Disease Control and Prevention, from 2003 to 2012 there have been 31 reported cases of PAM. Of those, 28 have been linked to recreational water, three from nose irrigation with contaminated water. These infections are more likely in Southern states but are extremely rare.

Florida Health officials said a person cannot be infected with the amoeba by drinking contaminated water, and the amoeba is not found in salt water.

The family continues to receive large support through the Facebook page, “Pray 4 Number 4,” where they post continuous updates of the boy.

“I hope that Zac continues to touch people and his time here is remembered forever,” said Jesse Reyna. “We thank everyone for being so caring and I know it’s going to be tough on us at first, but we have an awesome support team.”