Authors investigated the significance of a common human genetic variation of the NMDAR (show GRIN1 Proteins) NR3B subunit

Rs2240158 of GRIN3B was significantly associated with mismatch negativity in healthy subjects.

our findings suggest that the over-expression of NR3B subunit of NMDA receptor is a long lasting result of chronic opioid abuse.

These observations suggest that the genetic variation of the NR3B subunit of the NMDA receptor is not a risk factor for Alzheimer's dis pathogenesis

NR3B mRNA expression in the human hippocampal formation (CA1 (show CA1 Proteins)-CA4 (show CA4 Proteins) and dentate gyrus) and adjacent neocortex may have implications for understanding the role of NMDA receptors for physiological and pathological processes in these forebrain regions.

cross-talk between NR3B and NR4A receptors is a mechanism modulating the transcriptional activities of these orphan nuclear receptors

We tested whether genetic dysfunction of GRIN3B is implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS).