CLN5 is a soluble lysosomal protein with unknown function. Mutations in CLN5 lead to neuronal ceroid lipofuscinosis, a group of inherited neurodegenerative disorders that mainly affect children. CLN5 has eight potential ...

We conducted a series of stepwise NO3- additions to investigate the response of NO3- uptake to short-term (acute) changes in N concentration in 3 prairie streams. Observed NO3- uptake rates increased with short-term ...

Research to date regarding the relative advantages of local versus non-local sources of plant material for restoration has produced equivocal results. This research has typically focused on the performance of individual ...

Native tallgrass prairies support distinct dark septate endophyte (DSE) communities exemplified by periconia macrospinosa and Microdochium sp. that were recently identified as common root symbionts in this
system. Since ...

During translation initiation in Saccharomyces cerevisiae, an Arg- and Ser-rich segment (RS1 domain) of eIF4G and the Lys-rich segment (K-boxes) of eIF2β bind three common partners, eIF5, eIF1 and mRNA. Here we report that ...

Male and female, generally defined based on differences in gamete size and motility, likely have multiple independent origins, appearing to have evolved from isogamous organisms in various eukaryotic lineages. Recent studies ...

Wind energy development is targeted to meet 20% of U.S. energy demand by 2030. In Kansas, optimal sites for wind energy development often overlap with preferred habitats of Greater Prairie-Chickens (Tympanuchus cupido), a ...

Heteromorphic sex-determining regions or mating-type loci can contain large regions of non-recombining sequence where selection operates under different constraints than in freely recombining autosomal regions. Detailed ...

Long-term research on freshwater ecosystems provides insights that can be difficult to obtain from other approaches. Widespread monitoring of ecologically relevant water-quality parameters spanning decades can facilitate ...

Climate models for central United States predict increasing temperatures and greater variability in precipitation. Combined, these shifts in environmental conditions impact many ecosystem properties and services. Long‐term ...

Nonlinear ecological responses to anthropogenic forcing are common, and in some cases, the ecosystem responds by assuming a new stable state. This article is an overview and serves as the introduction to several articles ...

N and P often limit primary and secondary production in ecosystems, but they also can cause eutrophication and negatively influence sensitive species above a certain level or threshold point. Aquatic biodiversity can have ...

The mortality rate due to intestinal ischemia/reperfusion (IR) remains at 60-80%. As toll-like receptor (TLR) 4 has been shown to be critical for IR injury in several organs, including the intestine, and TLR9 is necessary ...

Retreating glaciers and the periglacial areas they vacate for organismal colonization produce a harsh environment of extreme radiation, nutrient limitations, and temperature oscillations. They provide a model system for ...

The paucity of data on migratory connections and an incomplete understanding of how mobile organisms use geographically separate areas have been obstacles to understanding coastal dynamics. Research on acoustically tagged ...

Stream metabolism is used to characterize the allochthonous and autochthonous basis of stream foodweb production. The metabolic rates of respiration and gross primary production often are estimated from changes in dissolved ...