Technavio has published a new market research report on the global hepatic encephalopathy (HE) therapeutics market from 2018-2022. (Graphic: Business Wire)

The report segments the global hepatic encephalopathy therapeutics
market by product (NADs and antibiotics) and by geography (the Americas,
EMEA, and APAC). It provides a detailed illustration of the major
factors influencing the market, including drivers, opportunities,
trends, and industry-specific challenges.

Here are some key findings of the global hepatic encephalopathy
therapeutics market, according to Technaviohealthcare
and life sciences researchers:

Availability of co-pay assistance programs: a major market driver

Emergence of novel treatment targets: emerging market trend

The Americas dominated the global hepatic encephalopathy therapeutics
market with close to 43% share in 2017

ASKA Pharmaceutical, COSMO PHARMACEUTICALS, Mallinckrodt, and Valeant
Biomet are some of the leading players in this market

Therapeutics are generally sold at a remarkably higher cost price to
provide better profit margins for the drugs. This is done to encourage
the vendors as they incur high development cost for the drug. Patients
might pay a certain cost, known as co-pay, for the therapeutic and the
insurer covers the remaining cost. In several instances, the burden of
co-pay has been taken over by the vendors. Such co-pay assistance has a
two-pronged impact on the market. It helps in increasing the patient
adherence to approved therapies by reducing the adoption of inexpensive
alternatives. It also increases the sales volume of therapeutics.

Technavio's sample reports are free of charge and contain multiple
sections of the report including the market size and forecast, drivers,
challenges, trends, and more.

Emergence of novel treatment targets: emerging market trend

At present, lactulose and rifaximin are the most commonly used
therapeutics to treat HE. Treatments targeting ammonia production and
removal are also emerging in the market. Inflammation is an important
factor that is associated with the progression and development of HE.
Therefore, there are various treatments that target inflammation. Some
of the most recent approaches include the use of probiotics, albumin
administration, and dialysis.

According to a senior analyst at Technavio for research oninfectious
and rare diseases, "Probiotics reduce the levels of ammonia
and endotoxin in the blood by introducing a microorganism into the body.
They also reduce inflammation and oxidative stress in hepatocytes. Thus,
they can be used in the treatment of HE. Probiotics also provide
secondary protection against further episodes through the replacement of
urease-producing species with non-urease-producing species. Hence, the
emergence of novel treatment targets will drive the growth of the global
HE therapeutics market during the forecast period."

Global market opportunities

The Americas dominated the global hepatic
encephalopathy therapeutics market, accounting for a share of
approximately 43% during the forecast period. The EMEA region accounted
for the second largest share in the market, and the APAC region
accounted for the least share in the market. During the forecast period,
the highest incremental growth is expected to originate from the
Americas.

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