At Comic-Con, Friday and Saturday are usually considered the “best” days. In the middle of the four-day convention, they are filled with the widest array of comic, movie, TV and video game panels and announcements. This year is no different. It looks like anyone who wants to see it all will have to make some very tough choices come Friday. Here are some highlights:

Comics

“Dan Piraro and Bizzaro”: Comic Con special guest Dan Piraro will provide an intimate look at his 27-year career, including some unpublished sketchbook images. The talk will conclude with a Q&A. 10:30-11:30, room 8.

“Spotlight on Lynn Johnston”: Another special guest at the Con this year, Johnston will reflect on her time spent with “For Better or Worse,” one of the more popular syndicated comic strips ever created, and will provide an update on what she’s doing now. 11:30-12:30, room 8.

“Bongo: Mylo Xyloto”: You may not be able to pronounce it, but chances are you might be interested in the fictional story behind Coldplay’s ambitious concept album “Mylo Xyloto.” A new comic series from Bongo will tell the story behind the music. 1:00-2:00, room 23ABC.

“Spotlight on Michael E. Uslan, The Boy Who Loved Batman”: Con special guest and longtime “Batman” graphic novelist will discuss his career and his role as Executive Producer on every “Batman” movie since Tim Burton’s original. He will also sign copies of his book, “The Boy Who Loved Batman.” 1:00-2:00, room 9.

“50th Anniversary of Marvel Superheroes”: 1962 was a banner year for comics. It birthed The Incredible Hulk, Spider-Man, Iron Man, Ant Man and Thor. In this panel, some of the original artists will reflect upon the creation of these characters, and why they’re still relevant 50 years later. 4:30-5:30, room 5AB.

Movies

“ParaNorman: Behind the Scenes”: The stars and creators of the upcoming stop-motion animated film will discuss the making of the movie and share some never-before-seen footage. Hall H, 10:45-11:45.

“Remixed Fairy Tales and Superhero Lore”: Brought on by the recent Hollywood reinterpretations of Snow White and Sleeping Beauty, panelists will discuss some of the enduring fantasy archetypes, and where they see them headed next. 11:30-12:30, room 5AB.

“Wreck-it Ralph: The Art of Story”: This clever new Disney animated film portrays the life of a video game villain who no longer wants to be the “bad guy.” Join the creators of the upcoming film as they discuss the inspirations behind the story. 3:00-4:00, room 6DE.

“Sony Panels”: Sony always brings out the big guns for the Con and this year is no different. Join the stars and creators of “Total Recall,” “Looper” and “Elysium” for looks at their upcoming films. 4:35-6:35, Hall H.

“Blade Runner: 30th Anniversary Celebration”: Join cast and crew members of the sci-fi classic as they reflect on the making and legacy of the film. 7:00-8:00, room 6BCF.

Television

“The Big Bang Theory Screening and Q&A”: Join the cast and crew for a discussion and screening of what’s in store for the geeky crew next season. 12:05-1:05, Hall H.

“Firefly 10-year Anniversary Reunion”: Join show creator Joss Whedon and the original crew of the Serenity for a reunion. The panel will include giveaways and special surprises. 12:30-1:30, Ballroom 20.

“666 Park Avenue Pilot Screening and Q&A”: Join the stars and creators of the new ABC horror drama for a screening and Q&A. 12:45-1:45, room 6BCF.

“AMC’s The Walking Dead”: The cast and crew will look back at the successful second season and give a sneak peek at what’s in store for season three. 1:25-2:25, Hall H.

“Game of Thrones Panel and Q&A”: Join the stars and creators of the wildly popular HBO drama for a look at the show that is sure to be full of surprises. The panel is moderated by George R.R. Martin, upon whose books the show is based. 2:45-3:45, Hall H.

Video Games

“Gears of War: Past, Present and Future”: Epic Games will be on hand to discuss the creation of the “Gears of War” video game series, and, hopefully, provide a look at the upcoming “Gears of War;Judgment.” 2:00-3:00, room 6BCF.

“The Art of Death and Darksiders II”: Creators will discuss the art and collaboration of the highly anticipated “Darksiders II,” including a look at both the video game and comic book adaptation. 3:30-4:30, room 5AB.

“The Last of Us: Behind the Scenes with Naughty Dog”: The creators of the “Uncharted” series offer a look into their new game, the E3 “best of show” award winner. Moderated by veteran game journalist Adam Sessler, the panel will feature an exclusive reveal of a new in-game cinematic. 5:00-6:00, room 25ABC.

“Resident Evil 6: The Fear and Horror!”: Join the producer of the highly anticipated sixth installment of the legendary survival horror franchise for exclusive information, live gameplay demos and a trailer premiere. 6:00-7:00, room 25ABC.