Detects protein complexes in dynamic protein interaction networks. DyCluster uses gene expression data to model protein-protein interaction (PPI) networks. It was tested using several biclustering techniques and various protein complex detection methods. The tool is able to increase the correctness and the quality of the results. It incorporates gene expression information to model the dynamics of PPI and to detect protein complexes in PPI networks accordingly.

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DyCluster in publications

[…] a fuzzy clustering algorithm, in which it establishes the fuzzy relationship between proteins and transforms it into some certain equivalence relation. this method can identify overlapping proteins. dycluster[] proposed a framework to model dynamic protein networks, it first construct a framework to identify protein complexes, and then detects complexes by clustering in a dynamic networks., […]