Samoilova's career began in 1955. She starred in over 50 Russian movies. She retired in 2008. Samoilova was born in Leningrad, Russia SFSR, Soviet Union.

On 3 May 2014, the eve of her 80th birthday, Samoilova was taken to hospital in Moscow. She had a serious condition with coronary heart disease and hypertension. She died, two days later on 4 May 2014.

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