Trypanosomes are unicellular eukaryotes which cause African Sleeping Sickness, which is endemic to subSaharan Africa. Trypanosomes can be easily grown as suspension cell lines in the laboratory, where they are straightforward to manipulate and genetically modify.

Through the study of protein structure, primarily using protein crystallography but also electron microscopy and small-angle X-ray scattering, we aim to probe crucial biomolecular interactions central to a variety of diseases.