Project: Biochemical and molecular characterization of a new mitochondrial encoded target site for acaricides

project duration

01-JAN-07 – 31-JAN-09

abstract

Bifenazate is a recent, very effective and highly selective acaricide. The mode of action and the target site of this compound are unknown. Recently, it was found that the compound is triggering a new mitochondrial target site, after activation to an active metabolite. The purpose of the project is the elucidation of the target site and the activation pathway. These findings will open new perspectives for the control of the economically important spider mite, Tetranychus urticae.