Objectives: This paper is a collection of plant samples that have been used traditionally in treatment, as it has been mentioned in Iranian old references books. This article contains gastroesophageal reflux disease [GERD] causes in Conventional medicine and a similar disease in Iranian Traditional of Medicine [ITM]. In this paper the most frequent materials for GERD three main etiological factors treatments is grouped. Methods: These drugs are scored based on their effects on gastric clearance of wet materials such as mucus[serous or Phlegm], which is according to avicenna is the most stomach dis-temperament. For this search studied 6 old references books Results: According to the reflux causes in ITM and Properties listed for medicines in books that can improve the grounds, 60 drug detected and are grouped. It is strongly significant pay attention to ITM therapeutics and herbs instead of GERD treatment in Conventional medicine.Conclusion: According to this study, the highest rating among the drugs commonly used in ITM for the treatment of gastric clearance of wet materials was awarded to pistacia atlantica. Key words: Iranian Traditional of Medicine [ITM], Gastroesophageal reflux disease [GERD], herbs