Before treatment:
Melina developed jaundice 1-2 weeks after she was born. she was prescribed medication and became better. When she was 5 months old, she had a fever and an epileptic seizure. The doctor prescribed medication to control it, and she never showed signs of it again. At 7-8 months old, she had spasms in the right arm, but they were left untreated. At the age of 1 year, she began to do rehabilitation training, but there was no improvement. She began to take Clonazepam 3mg before sleeping, 3 years ago to relieve the muscle tension. She was not able to speak, all four limbs were deformed and spastic, and both of her hands were abnormal and contracted. When she came to our medical center for stem cell treatment, she was diagnosed with cerebral palsy.
Her mood was good and her sleep patterns were normal. She was put on a semi-liquid diet. Her bowel movements and urination were normal. She was thin.

Admission PE:
Bp: 134/91mmHg. Hr: 110/min. Br: 24/min. Melina was thin, weight: 26kgs. Her thorax was asymmetrical. The respiratory sounds in both lungs were clear, with no dry or moist rales. Her heart sounds were strong, the cardiac rate was normal, with no obvious murmur in the valves. The abdomen was soft and flat, with no masses. All four limbs were contorted and spastic; she had deformity of the spinal column. Both of her hands were contracted and abnormal. She also had crossed-feet.

Nervous System Examination:
Melina Hartanto was alert and in good spirits. She was able to express herself a little with others. She moved her tongue around to express “yes” and said ”nggak” to express “no”. But she was not able to speak other words. She always wrinkled her eyes and eye brows, and smacked her lips. She was not able to perform the orientation ability, memory, or calculation examinations. She was able to close her eyes strongly. Both pupils were equal in size and round, both pupils were sensitive to light stimulus. Her eyes were not positioned correctly. Her eyeballs could move very well. The tongue and uvula were in the center of the oral cavity. The muscle tension of the whole body was higher; she didn’t cooperate with the other muscle examinations. The bilateral abdominal reflex, radial periosteal reflex, biceps reflex, triceps reflex and tendon reflex were abnormal. The bilateral ankle reflex, sucking reflex and palm jaw reflex were negative. The bilateral Babinski’s sign was negative. She was not able to cooperate with the Hoffmann’s sign examination, rapid rotation test, finger-to-finger test, finger-to-nose test or heel-knee-tibia test. The meningeal irritation sign was not examined.

Treatment:
After admission, Melina Hartanto received a full examination and was diagnosed with cerebral palsy and dystonia. She received 4 neural stem cell injections and 4 mesenchymal stem cell injections to repair the damaged nerves, replace the damaged nerve cells with normal cells, activate the new cells in her body, nourish the neurons, and improve her blood circulation and she also received physical rehabilitation.

Post-treatment:
After 22 days of treatment, Melina’s facial expressions were more natural, her face had less involuntary movements, and she was able to make simple sounds. The muscle tension was lower, she had less muscle spasms, her lateral curvature was better, her trunk was less contorted, and she was able to move her shoulders better. All four limbs were more flexible, both hands were less contracted and she had some reflex in the left middle abdominal area.

E-mails:

Date:2016-8-1

Good evening dr.Liu & dr.Peng, I want to inform about my sister condition, now my sister get more relax condition, but sometimes get spasm like usually, my sister's right lower leg can be opened wider if we pull her leg, all the blood examination result showed normal limit, only sodium valproat level slightly below normal limit, but in relax condition like now should the dose of sodium valproat be increased? these is the picture of my sister & blood examination result. Thank you.