3 briks daily (240 mL per brik) of Impact Advanced Recovery® to be take for 5 days before and after RC surgery

Dietary Supplement: Impact Advanced Recovery®

Placebo Comparator: Boost Plus®

3 briks daily (240 mL per brik) of Boost Plus® to be take for 5 days before and after RC surgery

Dietary Supplement: Boost Plus®

Detailed Description:

Radical cystectomy (RC) is the removal of the entire bladder and nearby organs that may contain cancer cells. It is a major surgery that can lead to breakdown of proteins in the body and a decreased immune response, both of which increase the risk of illness and death. Poor nutrition status before RC surgery is linked to a higher rate of death after surgery. Therefore, it is important to eat a balanced diet before and after RC surgery to avoid negative outcomes.

Studies show that patients who drink a nutritional supplement that may enhance the immune system before and after gastro-intestinal surgery may have fewer infections and shorter hospital stays after surgery. Patients with cancer of the colon/rectum, stomach, and pancreas who drank a similar immune-enhancing nutritional supplement before and after surgery also had fewer infections.

The purpose of this study is to attain pilot data for a larger trial.

Eligibility

Ages Eligible for Study:

40 Years to 90 Years

Genders Eligible for Study:

Male

Accepts Healthy Volunteers:

No

Criteria

Inclusion Criteria:

Men undergoing RC surgery for primary bladder cancer

Exclusion Criteria:

Patients with swallowing difficulties or unable to tolerate oral intake

Patients undergoing cystectomy for non-bladder primary malignancy or cancer type other than urothelial

Active viral infections such as Human immunodeficiency virus (HIV) positive, hepatitis, or who have a known immunodeficient state

Prior history of gouty arthritis or uric acid stones

Patients with milk, soy, or fish allergies

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01868087