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Elizabeth, depending on what your doctor is trying to treat with the Bactrim (sulfamethoxazole/trimethoprim), will determine how long he/she has prescribed your medication. Usually Bactrim is given for 10-14 days but you should start feeling better in about 3-4. It is important, however, that you continue to take the antibiotic for the full course, to ensure that the bacteria is killed and prevent the development of antibiotic resistance that can occur when patients don`t take their antibiotics for the full course of treatment (amongst other possible reasons of resistance including over-prescribing)

"Out and may be less susceptible to trimethoprim next time...."

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It begins it`s effects within 2 to 4 hours. How long until you notice a difference in symptoms due to the infection depends on your gender, what you are taking it for exactly (first time UTI or have you had many recently?) and how long you are meant to keep taking the tablets.
Assuming you are female, you should notice symptoms being relieved within the first 24 hours, even in as little as 12 hours. It is IMPORTANT to take the full course of medicine as directed even if your symptoms go away before you finish, otherwise the infection may not be wiped out and may be less susceptible to trimethoprim next time.

"Where as sulfameth will work 89% of the time..."

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Cipro will generally work 99% of the time, where as sulfameth will work 89% of the time. Cipro is very dangerous and carries a lot of long-term side effects that doctors forget to tell their patients. Only take cipro when sulfameth does not work.

"Have been on trimethoprim for acne for a couple of..."

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Have been on trimethoprim for acne for a couple of days now i have to keep going to the toliet (wee). Iam not drinking any more then usual even have to get up in the middle of the night is this normal.

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