I bought pounds and pounds of Accurate Nitro 100 on sale years ago and have been using it with great satisfaction in the 38. I use mostly 148 LWC and my charges range from 2.5 to 3.5 gr. of Nitro. Very accurate loads with any charges within the 2.5-3.5 range. The 158gr LSWC works equally well with Nitro. Incidently the 3.5 gr. charge also is my standard .45 acp load with 200 gr. LSWC slugs. Nice soft shooting easy on the recoil load.