ApplePhenon® Apple Polyphenols

ApplePhenon® is carefully extracted from specially selected wildcrafted immature green apples from Central Asia, the “Land of the Original Apple.” Using a proprietary gentle extraction process, ApplePhenon® from BGG preserves the highest concentration of apple polyphenols, strong antioxidant activity and an optimized profile of proanthocyanidins. Clinical studies have shown that ApplePhenon® plays an effective role in antioxidant, weight, glucose management, dental care, cardiovascular protection, athletic enhancement and allergy support. ApplePhenon® has been GRAS self-affirmed in USA and can be used in all food, beverage and dietary supplement applications.

ApplePhenon® by BGG is a patented, proprietary polyphenol extract produced from wild, unripe apples from the Central Asia region where the species originated. Using a proprietary mild extraction process and advanced purification technology, ApplePhenon® is produced to preserve high concentrations of apple polyphenols, strong antioxidant properties and optimized profile of proanthocyanidins. The starting raw material for producing ApplePhenon® are unripe apples containing at least ten times the level of polyphenols found in ripe apples.

The ORAC (Oxygen Radical Absorbance Capacity) value of ApplePhenon® is extremely high in comparison to other polyphenol products.

WHAT IS APPLEPHENON®Polyphenols extracted from wild unripe apples

HIGH BIOAVAILABILITY OF APPLEPHENON®Oligomeric procyanidins in ApplePhenon® are more easily absorbed in blood than other polyphenol products.

NATURAL ANTIOXIDANTThe ORAC (Oxygen Radical Absorbance Capacity) value of ApplePhenon® is extremely high in comparison to other polyphenol products.

CLINICALLY SUPPORTED BENEFITS of APPLEPHENON

WEIGHT MANAGEMENT

Pre-clinical studies demonstrated that ApplePhenon® decreases the transcription of genes involved in fatty acid synthesis similarly to a restricted food diet. It may also contribute to suppression of visceral adipose tissue accumulation. Furthermore, is has been shown that administering apple polyphenols markedly decreases the Firmicutes/Bacteroidetes ratio and increases the proportion of Akkermansia by a factor of eight. This influences the gut microbiota and the intestinal metalolome (which has beneficial effects on metabolic homeostasis).

Clinically, ApplePhenon® at 600 mg per day has proven effective in decreasing visceral fat within an 8 to 12 week time frame in a randomized, double-blind and placebo controlled study in 94 subjects with BMI 25-30. In addition, in a smaller group of 30 subjects (BMI 18-30) an excessive dose of ApplePhenon® for 4 weeks has been shown to have no deleterious effects.

Similarly, the visceral fat area and the level of adiponectin in the Applephenon® group improved as compared to the control group in a 20 week (4 weeks observation, 12 weeks treatment, 4 weeks follow up) randomized, double-blind, placebo-controlled comparative study. (Study references can be found on the downloadable PDF brochure)

CARDIOVASCULAR SUPPORT

Several clinical studies support the cardiovascular health activity of Applephenon®. In a 4-week pilot study with 48 healthy volunteers with cholesterol levels between 200 and 260 mg/dL, a dose-dependent decrease in total cholesterol and LDL cholesterol and an increase in HDL cholesterol were found at dosages of 300mg, 600mg and 1500mg per day. These results were corroborated in a longer duration study with 71 moderately-overweight subjects (BMI 23 – 30 and total cholesterol averaging 220 mg/dL). Finally, in a small crossover study on 6 volunteers, ApplePhenon® at 600mg per day was shown to inhibit the absorption of triglycerides from a high-fat diet. (Study references can be found on the downloadable PDF brochure)

DENTAL CARE

ApplePhenon® can inhibit glucosyltransferase (GTE) of dental bacteria Streptococci mutans and Porphyromonas gingivalis, therefore preventing dental plaque formation. A clinical study on twenty 19 – 20 year old women who rinsed their mouths with 10 mL of ApplePhenon® solution (0.5 mg/mL) three to five times a day for three days showed a significant decrease of dental plaque formation. Chewing gum with a low dose of 0.024% ApplePhenon® for five minutes can inhibit the production of methanethiol (MeSH), the main cause of bad breath.

ATHLETIC PERFORMANCE IMPROVEMENT

In a clinical trial study on college athletes, 20 subjects (male and female) randomly took ApplePhenon® (1,200 mg/day), CoQ10 (300 mg/day) and placebo for 8 days (crossover). On day 9, performance was tested through a bicycle ergonomic exercise load measuring pedal speed differences between the first 30 minutes and the last 30 minutes. Compared with the CoQ10 group and the placebo group, the ApplePhenon® group experienced a significant improvement in performance levels.