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Josh Newberg of 247Sports first reported Tuesday morning Straub had been suspended indefinitely. Late Tuesday afternoon, the school confirmed the resignation. Straub didn't return a text message.

"USF Athletics has high expectations for each and every student-athlete, coach and staff member," athletic director Mark Harlan said in a statement released by the school. "To that end, I have accepted the resignation of Hans Straub from the position of head strength and conditioning coach. … A national search for his replacement will begin immediately."

Straub, entering his second year at USF, issued a tweet shortly after the 49ers drafted Lynch in the fifth round Saturday:

Thought an organization with 5 Super Bowl titles would have a stricter draft criteria. Clearly, integrity & character are not a priority

The tweet has since been removed. Speaking on the American Athletic Conference coaches spring teleconference Tuesday morning, coach Willie Taggart said USF's administration was handling the matter.

"First off I would like to say I am so proud and so happy for Aaron Lynch being drafted by the 49ers," Taggart said. "Very disappointed in the tweet. Hans knows how disappointed I am, Mark (Harlan) knows how disappointed I am, our football team knows how disappointed I am."

Lynch, a Notre Dame transfer, played one season at USF. He led the Bulls in sacks (six) and earned first-team all-conference honors, but struggled with consistency and composure. San Francisco signed Lynch on Tuesday.

Niners coach Jim Harbaugh told NFL Network that Taggart vouched for Lynch. "I think from a character standpoint, Aaron wasn't any different than any other kid, and he worked really hard," Taggart said.