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Immediately Dangerous to Life or Health Concentrations (IDLH)

Description of Substance: Colorless liquid with a slightly sharp odor.

LEL:. . Noncombustible Liquid

Original (SCP) IDLH: 75 ppm

Basis for original (SCP) IDLH: The chosen IDLH is based on the statement by AIHA [1957] that the short exposure tolerance is unknown for man, but is probably 75 ppm. AIHA [1957] also reported that a single 4­hour exposure to 75 ppm was tolerated by mice but higher concentrations produced delayed deaths [Svirbely]. According to AIHA [1957], concentrations in excess of 1,000 ppm would probably be lethal after a few minutes [Svirbely].

Short-term exposure guidelines: None developed

ACUTE TOXICITY DATA:

Lethal concentration data:

Species

Reference

LC50

(ppm)

LCLo

(ppm)

Time

Adjusted 0.5-hr

LC (CF)

Derived value

Rat

Gig Tr Prof Zabol 1977

1,418

-----

4 hr

2,836 ppm (2.0)

284 ppm

Mouse

Stokinger & Scheel 1962

-----

227

?

?

?

Lethal dose data:

Species

Reference

Route

LD50

(mg/kg)

LDLo

(mg/kg)

Adjusted LD

Derived value

Mouse

Lyazsky et al. 1983

oral

2,000

-----

9,929 ppm

993 ppm

Other animal data: It has been reported that mice tolerated a single 4­hour exposure to 75 ppm [Svirbely].

Human data: It has been stated that although the short­term exposure tolerance is unknown, it is probably about 75 ppm [AIHA 1957]. Death has resulted in a man who drank 100 ml [Raukhverger and Solodko 1974].

Revised IDLH: 75 ppm [Unchanged]

Basis for revised IDLH: Based on acute inhalation data in humans [AIHA 1957] and animals [Svirbely], the original IDLH for hydrogen peroxide (75 ppm) is not being revised at this time.