Single dose fMRI effects of Guanfacine and Lisdexamfetamine in ADHD adolescents

This study looks at two different types of medication that are sometimes used in treatment of children with Attention Deficit Hyperactivity Disorder (ADHD). The medications we are studying are called Lisdexamfetamine and Guanfacine. We would like to find out how these two drugs acts on the brain of children and adolescents with ADHD. This is where you can help us!

This is a Magnetic Resonance Imaging (MRI) study which means that you will be asked to come to the Centre for Neuroimaging Sciences at Denmark Hill to have some brain scans. You will be asked to do some computer tasks while lying still in the scanner. We would like you to come in for four days within 3 weeks., i.e. for a screening appointment and three scans separated by a week each. We can also give you a picture of your brain!

Details:

We are looking for:

We are looking for participants who:

Boys with ADHD (10-18 years)

Never medicated for ADHD or non-medicated for at least one year

Right-handed

Weight: 25-80 kg

You won't be able to participate if you have:

Other psychiatric or neurological disorder

History of substance abuse

Metal in your body (e.g. braces, pacemaker)

History of cardiac problems

Location:

London

Expenses:

You will get £20 for the screening appointment and £50 for each scan (a total of £170 for completing all study visits).