Applications/Dilutions

Dilutions

Western Blot

Immunohistochemistry

Immunohistochemistry-Paraffin

Application Notes

There are numerous isoforms of TREX1. Researchers are encouraged to use an online tool like NCBI's BLAST to determine if the antibody is suitable for use in their testing.
Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage

Store at 4C in the dark.

Buffer

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Purity

Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TREX1 Antibody (41M5F2) [DyLight 680]

3'-5' exonuclease TREX1

AGS1

Aicardi-Goutieres syndrome 1

CRV

DKFZp434J0310

DNase III

DRN3

EC 3.1.11.2

HERNS

three prime repair exonuclease 1,3' repair exonuclease 1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Research Areas for TREX1 Antibody (NBP2-22394FR)

Blogs on TREX1.

Dinosaur Protein Names: InfographicTrex1 the protein is involved in DNA damage response. Tyrannosaurus rex (T. rex) the dinosaur lived during the Cretaceous Period. Raptor the protein is a regulator of mTOR activity. Velociraptors the dinosaurs lived during the Cretaceous Period. Learn... Read full blog post.

Trex1 (3'-5' exonuclease TREX1, DNase III)This gene encodes the major 3' to 5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that appears to provide proofreading for checkpoint signaling after DNA damage in response to oxidative stress and apoptosis. It is ubiqui... Read full blog post.

Contact Information

Product PDFs

Calculators

Concentration Calculator

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

Volume

=

Mass

÷

Concentration

Review this Product

Be the first to review our TREX1 Antibody (41M5F2) [DyLight 680] and receive a gift card or discount.