A hardworking Queens man was killed two blocks from home when his drunken buddy’s car collided with another vehicle early yesterday, cops said.

Rafael Ramirez, 23, of Jamaica, who was working nights on a street construction crew to support his mother, was being driven home by his friend Ramone Estevez, 24, when the crash occurred at about 5:20 a.m.

“The guy works from 7 p.m. to 5 a.m. He was so good. He was the pillar of our family,” his grieving uncle David Castellanos said. “He helped his mom by paying the rent.”

Witnesses said the driver of the other vehicle, a 2002 Nissan, ran off after the accident at the 191st Street and Hillside Avenue in Jamaica.

“I heard the crash, but when I came outside, the driver was already running,” said Sean Vincent, 21, who lives nearby.