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Six years ago, I was diagnosed with multiple myeloma, and recently I noticed that the bone of my right lower jaw is much thinner than the left side. What would cause the loss of the bone there and not on my left side?

There are two possible causes for the jaw asymmetry you describe. First, if the myeloma involved the jaw, the treatment you got for the disease may have killed off the cells which had previously destroyed the bone in that location. With no tissue (bone or cancer) in that location, the jaw may appear "thinned."

Another possibility is related to a side effect of drugs called bisphosphonates. Zometa [zoledronate], the bisphosphonate most commonly used in myeloma to prevent further bone breakdown, is associated with a very rare condition called osteonecrosis of the jaw. Osteonecrosis can be painful and is often related to pre-existing dental problems.

Overall, I favor the first explanation in your case, but you should check with your oncologist.