"We feel badly for Sean," Coughlin said, via The Star-Ledger. "Here's a guy that's come in here, not knowing our system, has played well for us. He's been there when we've needed him, he's done a heck of a job, and we all feel bad about this taking place at that point in time last night. It is a serious injury, and we're very upset about that."

Locklear played seven seasons in Seattle and one in Washington before joining the Giants.

The 31-year-old started 10 games at right tackle in his first year with New York. His injury occurred on a fourth-quarter run play when his right leg got caught between Giants running back Ahmad Bradshaw and Redskins safety Madieu Williams, bending the 6-foot-4, 310-pound tackle the wrong way.