The Spanish Journal of Anesthesiology and Resuscitation is the scientific body of the Spanish Society of Anesthesiology, Resuscitation and Pain Therapy. The Journal publishes scientific articles of all areas within its specialty: clinical anesthesia, resuscitation-intensive medicine and critical care, diagnosis and treatment of acute and chronic pain, urgent care and emergencies and studies on basic science and related fields

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CiteScore 2018

CiteScore measures average citations received per document published. Read more

CiteScore 2018

0.43

SRJ is a prestige metric based on the idea that not all citations are the same. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal's impact.

SJR

0.236

SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field.

To evaluate the effectiveness of intravenous iron treatment, with or without associated erythropoietin (rHuEPO), measured as hemoglobin (Hb) increase. The relationships between the Hb increase and parameters used to evaluate anemia were analyzed.

Materials and methods

Retrospective observational study carried out in two third-level hospitals between January 2005 and December 2009. The study included patients with iron deficiency anemia scheduled for elective orthopaedic surgery and treated with intravenous iron sucrose alone or associated with rHuEPO. Treatment efficacy was analyzed based on the Hb increase from baseline to just before surgery.

Results

A total of 412 patients who received a median of 800mg of iron sucrose were included; 125 of them (30.4%) additionally received 2.4 vials of rHuEPO. The Hb increase was 0.8 (1.1)g/dL in patients treated with intravenous iron and 1.5 (1.3)g/dL in those additionally given rHuEPO (P<.01). The percentage of hypochromic red blood cells (r=0.52) and soluble transferrin receptor (r=0.59) value were significantly correlated to the Hb increase in patients receiving iron.

Conclusions

In patients with iron deficiency anemia, the effectiveness of iron sucrose treatment to optimize Hb before surgery was moderate; adjuvant administration of erythropoietin improved the results. Determination of functional iron status parameters may improve the treatment effectiveness.