Summary

Secondary Antibodies

Negative Isotype Controls

Useful Reagents

Positive Controls

Histology Controls

More Images

References

Reviews

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Human anti carcinoembryonic antigen (CEA) antibody is a research grade biosimilar of the monoclonal diagnostic antibody drug arcitumomab. It is a recombinant human IgG1 kappa antibody with variable regions from the hybridoma arcitumomab.

Human anti carcinoembryonic antigen antibody recognizes CEA, a glycoprotein involved in cell adhesion. Overexpression of CEA is associated with a number of gastrointestinal tract carcinomas. The diagnostic drug arcitumomab was used in the diagnosis of recurrent or metastatic colorectal carcinoma.

This product is for research use only, it is NOT FOR DIAGNOSTIC USE.

Intended Use

Target Species

Human

Species Cross-Reactivity

Target Species

Cross Reactivity

Human

Rat

N.B. Antibody reactivity and working conditions may vary between species.

Product Form

Human IgG1 kappa recombinant antibody - liquid

Reconstitution

Preparation

Purified IgG prepared by affinity chromatography on Protein A

Preservative Stabilisers

0.02% Proclin 300

Immunogen

Human carcinoembryonic antigen

Purity

>98% by SDS PAGE

Approx. Protein Concentrations

IgG concentration 1.0 mg/ml

Reagents In The Kit

Preparing The Antibody

Test Principle

Buffer Solution

Phosphate buffered saline

Storage

Store at +4oC or at -20oC if preferred.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Shelf Life

12 months from date of despatch

Acknowledgements

Licensed Use

For in vitro research purposes only. Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals.

Regulatory

For research purposes only

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name

Yes

No

Min Dilution

Max Dilution

Immunofluorescence

Immunohistology - Paraffin

Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.