On 3 February 2009, Ghost was named the new president of Epic Records. She replaced Charlie Walk, who left at the end of 2008 to start his own company.

Ghost co-wrote, with Scott McFarnon and Ian Dench, "Red" a top 5 hit for Daniel Merriweather in the UK in May 2009 and " For the Glory" and"Vanity Kills" by Ian Brown, which she co-wrote with Ian and Dave McCracken. She also co-wrote and produced the Shakira multi-platinum selling single "Gypsy", from the album She Wolf.

Amanda left her position as president of Epic Records in 2010.[1] and is now the CEO of her own record label, Outsiders, a joint venture with The Universal Music Group. In 2011 she was executive producer for the Scissor Sisters album Magic Hour, and co-wrote the smash hit "Only The Horses", co-produced by Calvin Harris. She co-wrote two songs for the Florence and The Machine album Ceremonials, and has more recently collaborated with John Legend, Sub Focus and ASAP Rocky.

Ghost is a three time Ivor Novello Award winner, a Golden Globe nominee, and has been nominated for three Grammy Awards. One of the latter was as co-producer of two tracks on Beyoncé's album, I Am... Sasha Fierce, which was nominated as Album of the Year, and the other for "Once in a Lifetime", which she co-wrote with Scott McFarnon, Ian Dench, Jody Street, James Dring and Beyoncé. The song was the title track from Beyoncé's film, Cadillac Records and was nominated for the Best Song Written for a Motion Picture Award.