Research

IRB Number: 21072(inactive trial)

Institutional Review Board, Hospital for Special Surgery

July 06, 2005

The safety of study participants is our top priority. The trial is approved and periodically reviewed by an Institutional Review Board (IRB), which includes doctors, administrators, ethicists, and members of the general public. The safety of clinical trials is reviewed by the U.S. Food and Drug Administration.

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Principal Investigator

Co-Investigators

Summary

The purpose of the research is to investigate if combinations of the genetic prothrombotic factors such as, AT III, PAI-1 4G/4G, and prothrombin G20210A demonstrate an association with blood clotting therefore increasing the risk of developing hypercoagulation-based complications such as Deep Venous Thrombosis and Pulmonary Emboli. The researchers want to learn if a blood test could help to determine which patients are at a higher risk of developing these clots. They want to determine if people with a positive test for a blood clot also have certain molecular markers (chemicals) in their blood compared to people who do not have a clot. The researchers expect to enroll 500 patients in this research study which will involve one visit, lasting about fifteen minutes.