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El Gamasy was born on 9 September 1921 in Batanoon, Monufia Governorate, Egypt. He was one of two brothers and five sisters. After high school, El Gamassy joined the Egyptian Military Academy and was commissioned in 1941 in an infantry regiment. As a Major, he was GSO-II of an infantry battalion during the 1948 War.

El-Gamasy was well known for being the Chief of Operations for all Ground Forces participating in the 1973 October War. He was also appointed by Anwar Sadat as the head of the group that participated in the disengagement talks on 28 October, at "Kilometer 101". Reportedly, he was sad for the lost souls at the war when the American secretary of state Henry Kissinger announced that the president Sadat agreed to pull the main part of the Egyptian forces from the east side of the Suez Canal in exchange of the withdrawal of Israeli forces from the west side of the Suez Canal and retreat back into the depth of Sinai.