On mine if i press gently on the right side of the touch screen, it clicks down as if it is loose on the internal board of the DS. This means when i calibrate it i need to do it slightly to the left of all the red markers and lose about 2mm on the right of my screen when playing touch screen games.

my daughters touch screen is way out and wont calibrate , this has absolutly nothing to do with the r4ds as said previous you calibrate the screen without the use of the r4ds !
i have bought a new touch screen from dealextreme and will fit it when it arrives , recently replaced the shell (case) so im hopeing the touchscreen should be easy enough.