Articles Related to ELM

Recent literature has suggested that junior doctors’ knowledge of ionising radiation is inadequate. Advances in technology and availability have led to of these investigations being readily requested. Exposure is associated with adverse risks especially malignancy; therefore in accordance with the Ionising Radiation (Medical Exposures) Regulation (IR(ME)R), clinicians should be aware of radiation doses and their legal responsibility as referrers.

Parasitic gastroenteritis caused by gastrointestinal nematodes (GIN) continues to be a major constraint against profitable small ruminant production. The increasing prevalence and severity of anthelmintic-resistant nematodes in many parts of the world has led to a search for non-chemical control options.

Eugenol (EU) and ibuprofene (IBU) were covalently bound to a bi-functionalized PEG, used as molecular carrier of drugs and the release kinetics of the two bioactive molecules was studied in vitro in buffer solution at pH 7.4, in simulated gastric fluid and in mouse plasma.

The high mortality associated with ovarian cancer is generally related to the development of drug-resistant disease. HMGA2 protein, a member of the high-mobility group AT-hook (HMGA) family of non-histone chromatin binding factors, is overexpressed in high-grade serous ovarian and tubal carcinomas, though little is known about its contribution to disease progression and drug resistance. We sought to assess whether compositional changes in HMGA2 production were associated with ovarian cancer progression.

Hydatid disease is caused by the larval form of parasitic tapeworm; Echinococcus granulosus. Primary spinal hydatid disease is rare. Primary bone localization is rare and it accounts between 0.5% and 4%. Spinal localization accounts for less than 1%. The infection may be misdiagnosed initially.

Ascariasis is the most common helminthic infection in the world and is seen mostly in the developing countries of Asia. We report a case of heavy worm infestation in a 2-year-old child who presented with worms in small bowel, common bile duct and liver with abscesses. He was managed conservatively and recovered well without any sequalae.