Depends what your requirements are. For example, I need centralised management and recovery for I use PGP WDE. But I also use TrueCrypt for file encryption but I haven't looked into TrueCrypt Whole Disk.

i tried Truecrypt, yes it works but there is problem when i need to share my work files to my colleagues, you don't want to share your Truecrypt partition file, do you? i had another bad experience with truecrypt that i forgot my vault's pin and i had no way of open the vault till now. my company now uses [url=http://www.bloombase.com]Bloombase Keyparc[/ur] instead interesting it encrypts on the file level rather than full disk that i can send over the .kpp secured file thru emails to my friends and workmates.