Before treatment:
Beth was unable to get up from bed 1 year ago. The lower limbs developed stiffness and weakness, and she always fell down. The symptoms continued worsening. She went to her local hospital and was diagnosed with amyotrophic lateral sclerosis. At present, it is hard for her to walk by herself, she needs support to walk. She feels uncomfortable when she breathes. She wanted better treatment for her condition so she came to our hospital and was diagnosed with ALS.
Her spirit was good. She didn’t get enough sleep. Her diet, urination routine and bowel movements were normal.

Admission PE:
Bp: 137/89mmHg, Hr: 75/min, breathing rate: 18/mim, body temperature: 36.6 degrees. Finger oxygen saturation is 94%. Nutrition status is normal, with a normal physical development. There is no injury or bleeding spots on her skin and mucosa, no blausucht, no throat congestion, and her tonsils were not swollen. Chest develop is normal, the respiratory sounds in both lungs were clear, the breathing sounds in the lower section of the lungs is slight weak, there is no dry or moist rales. The heart beat is powerful with regular cardiac rhythm, with no obvious murmur in the valves. The abdomen is distended, with no masses or tenderness. The liver and spleen are normal. There is no edema in the lower limbs.

Nervous System Examination:
Beth was alert and her spirit was good. Her speech was clear. She had some memory loss, the orientation and calculation abilities were normal. Both pupils were equal in size and round, their diameter was 3mm, and reacted well to light. The eyeballs can move freely. There was no nystagmus. The bilateral forehead wrinkle pattern and nasolabial fold were symmetrical. The tongue was centered, with mild muscle atrophy. The teeth were shown without deflection. The cheeks could be expanded powerfully and her chewing ability was good. The soft plate could not be raised strongly. Beth could close her eyes normally. The neck muscles were soft, and she could move her head freely. The shoulders could be shrugged normally. The muscle power of the left upper limb was 4- degrees because of a previous injury. The muscle power of the right upper limb was 5 degrees. The gripping force of both hands was 5 degrees. The muscle power of the lower limbs was 2+ degrees. The muscle tone of all 4 limbs was nearly normal. Ankle clonus was negative. The bilateral bicipital tendon reflex, triceps brachii muscle tendon reflex and radial periosteal reflex were active. The bilateral patellar tendon reflex was hyperactive. The Achilles tendon reflex was not induced by examination. The bilateral palm jaw reflex was negative. The bilateral Hoffmann sign was negative, the bilateral Rossolimo sign was positive, the Babinski sign was neutral. The finger-to-nose test, the fast alternating test and heel-knee-tibia test were basically normal. The meningeal irritation sign was negative.

Treatment:
Beth received all the relevant examinations and was diagnosed with 1. ALS 2. Hypertension. She received 3 neural stem cell injections and 3 mesenchymal stem cell injections to repair her damaged nerves, replace the dead cells with new injected cells, activate the stem cells in her body, regulate her immune system, improve her blood circulation and nourish the neurons. This was accompanied with rehabilitation therapies.

Post-treatment:
After 15 days of treatment, Beth’s respiratory functioning was improved. The finger oxygen saturation was 95-98%, the blood pressure was in good control, and much more stable at 120-127/72-80 mmHg. The lower limbs were flexible and powerful. The lower limbs can be raised much higher than before. The muscle power had increased to around 3 degrees. Both her energy and spirit were improved.