I've got a wireless Officejet 6600 and CUPS automatically detects the printer. I tell it to use the hp-officejet_6600.ppd file, but it still won't print.

Where did you get the PPD file? This is one of the great Puppy myths - that you can install a printer just by supplying its PPD file. Unfortunately, the source of this information is repeated in each new Puppy.

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After searching and reading lots of threads here on the subject I'm really confused about what I need to do to make this work.

Have you read here? The hplip_print-3.12.10a.pet supports your printer.

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