I have UC and I've been on Pentasa for a few weeks (4000mg) and Canasa supp. Anyone have insomnia with the Pentasa? I'm also pregnant. I was sleeping like a baby before I started taking the meds. Now I'm sleeping 3-4 hours a night and I'm dead tired during work. It's affecting my performance. Any other thoughts?

I don't recall ever seeing anyone complain of insomnia with Pentasa and I never experienced it. It also isn't listed as a potential side effect. None of which means it couldn't be having this effect on you, unfortunately.

How far along in your pregnancy are you, demchim? Sometimes that can interfere with sleeping, too. And are you taking any other medicatons?

Thanks, Judy.I'm 13 weeks pregnant. Flared 7 weeks into my pregnancy. Between the nausea/vomiting of pregnancy, the UC flare with anemia, and lack of sleep, I feel like a zombie. Maybe it's just increased anxiety and pregnancy. Right now I'm only taking Pentasa and Canasa. I'm trying to hold off on steroids.

Darn, demchim, you're just starting your second trimester. This is when the nausea usually starts going away and you feel good. Have you tried a nice warm bath and a cup of chamomile tea just before bedtime? And sometimes it helps if you avoid television or the computer before bedtime. Something about looking at the lit screen seems to make the brain release more "awake" chemicals. If you still can't sleep, try to rest and play some soft music, read something calming. Give up the idea that you're "supposed" to go to sleep now. The more you worry about it the more awake you get, unfortunately.