Don’t have 288 hours to devote to ‘The Simpsons’ marathon? Check out this breakdown of when to catch the best episodes and funniest guest stars.

A 12-day marathon of nonstop “Simpsons”? Just hook it to my veins!

Running Thursday, Aug. 21 through Monday, Sept. 1, FXX is airing all 552 episodes from 25 seasons of the groundbreaking Fox animated sitcom, including the 2007 movie, back to back, all day long. It’s the longest marathon ever on television.

But is watching more than 200 hours worth of TV unpossible? Probably, and you’d have to seriously embiggen your DVR memory to catch it all. Luckily, you’ve got our expert guide to the marathon so you can make sure you catch all the best bits.

Comic Book GuyPhoto: Fox

Most sarcastic Comic Book Guy zinger

Episode: “Marge Be Not Proud” from Season 7 (airing Sunday, Aug. 24, at 7 a.m.)

Comic Book Guy dispenses sarcasm and nerdy put-downs very much like … well, like a real guy who works at a comic book shop. His finest barb comes at Bart’s expense, when he tells the confused boy, seeking to buy a video game for $1: “Oh please, take my $59, I don’t want it.”

Best Conan O’Brien contribution

Then-unknown Conan O’Brien wrote three episodes and produced a bunch more that helped defined the golden era of the series. The highlight is this episode’s “The Monorail Song” — a parody of show tunes from “The Music Man,” in which a huckster sells Springfield on a shoddy transportation option.

“Homer At The Bat”Photo: Fox

If you only watch three episodes…

1. Friday, Aug. 22, at 11:30 a.m.: “Homer at the Bat”

Possibly the most impressive arrangement of Major League Baseball players in an animated show of all time, this Season 3 winner stars Darryl Strawberry, Don Mattingly, Wade Boggs, Jose Canseco, Roger Clemens, Ken Griffey Jr., Ozzie Smith, Mike Scioscia and Steve Sax as themselves, whom Mr. Burns hires as ringers for the company softball game. If you’ve never seen Wade Boggs and Barney arguing over who was the greatest English prime minister, you haven’t lived.

“A Fish Called Selma”Photo: Fox

2. Sunday, Aug. 24, at 11 a.m.: “A Fish Called Selma”

Phil Hartman, you were taken from us too soon. In this classic from Season 7, Hartman’s Troy McClure marries Selma just to help his acting career. It works, and we were bestowed a gift from the comedy gods called the “Stop the Planet of the Apes, I Want to Get Off!” musical, featuring the “Amadeus”-aping song “Dr. Zaius.”

“You Only Move Twice”Photo: Fox

3. Sunday, Aug. 24, at 3 p.m.: “You Only Move Twice”

The apex of all things “Simpsons” that ever was and ever will be, this Season 8 episode marks the great Albert Brooks’ final appearance on the show (though he did return for the 2007 movie). He plays Hank Scorpio, Homer’s new boss, who’s half Richard Branson and half Bond villain. Hop in a hammock and take it all in.

Awesome guest stars

Michael Jackson

Photo: Fox
The King of Pop went uncredited in this episode, but it is indeed him voicing “Michael Jackson”, a k a an obese mental patient who thinks he’s Michael Jackson. (“Stark Raving Dad” from Season 3, airing Friday, Aug. 22, at 3:30 a.m.)

The cast of “Cheers”

When Homer gets banned from Moe’s, he scours Springfield for a new watering hole, including one where everybody knows your name. Ted Danson, Woody Harrelson, Rhea Perlman, John Ratzenberger and George Wendt lend their voices for this mini “Cheers” reunion. (“Fear of Flying” from Season 6, airing Saturday, Aug. 23, at 6:30 p.m.)

Dustin Hoffman

Patrick Stewart

The esteemed thespian brings gravitas to the role of the head of the Stonecutters secret society, which, after Homer ruins everything, is redubbed the No Homers Society. (“Homer the Great” from Season 6, airing Saturday, Aug. 23, at 7 p.m.)

Aisha Tyler’s favorite episode

Groundskeeper WilliePhoto: Fox

“ ‘Treehouse of Horror V’ has a brilliant combination of big laughs and delicate irony — such as when Homer rejects an alternate reality where he believes donuts don’t exist, time-traveling away just moments before donuts start raining from the sky,” says the comedian, who voices Lana on the animated series “Archer.” “Plus Maggie gets to try on James Earl Jones’ voice, then axes Groundskeeper Willie.” (From Season 6; airing Saturday, Aug. 23, at 4 p.m.)

Werid Al Yankovic’s Favorite Episode

“Three Gays of the Condo”Photo: Fox

“ ‘Three Gays of the Condo’ is one of my favorites because the jokes are hilarious, the story line is engaging, and I’m in it,” says the song-parodist. “I have the honor of serenading Marge in an effort to get her to reconcile with her husband.” (From Season 14; airing Wednesday, Aug. 27, at 7:30 p.m.)

Eugene Mirman’s Favorite Quote

KodosPhoto: Fox

“Don’t blame me, I voted for Kodos,” from “Treehouse of Horror VII.”

“That was the first [example of an] adult mainstream cartoon having something that was just clever politically,” says the voice of Gene on “Bob’s Burgers.” (From Season 8; airing Sunday, Aug. 24, at 2:30 p.m.)