Tuberculosis (TB) has been known as a contagious disease. This disease is due to infection of Tubercle bacillus. WHO found that Indonesia is in 3rd rank in morbidity rate beside India and China. There were 140.000 TB patients died every year or one TB patient died every 4 minutes in those above countries and there was contamination in every 2 seconds Tuberculous spondilytis is one among the extrapulmonal tuberculosis that may caused severe physical handicap. A large number of references had been studied, it is very important to understand its pathophysiology in order to have satisfactory end results in treating tuberculosis and to decrease the physical handicap as well as to decrease the mortality and morbidity rates.