Note=Chromosomal aberrations involving BCL6 may be a cause of B-cell non-Hodgkin lymphoma. Translocation t(3;14)(q27;q32); translocation t(3;22)(q27;q11) with immunoglobulin gene regions.Note=A chromosomal aberration involving BCL6 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with POU2AF1/OBF1.Note=A chromosomal aberration involving BCL6 may be a cause of lymphoma. Translocation t(3;4)(q27;p11) with ARHH/TTF.

序列相似性

Contains 1 BTB (POZ) domain.Contains 6 C2H2-type zinc fingers.

结构域

The BTB domain mediates homodimerization. Its dimer interface mediates peptide binding such as to corepressors BCOR and NCOR2.

翻译后修饰

Phosphorylated by MAPK1 in response to antigen receptor activation. Phosphorylation induces its degradation by ubiquitin/proteasome pathway.

Thank you for your email. The free of charge replacement vial is being sent to your attention on order reference # 110953 and you should receive it Wednesday.
Please let me know how it works out for you and if you have any additional questions.

Thank you for your email and for re-sending the image. Unfortunately, without the molecular weight markers on the image, it's difficult to determine the band size. But based on what you previously said, it seems that in the lanes that contain the Ramos...

Thank you for your enquiry and I'm sorry to hear that you are experiencing difficulty with ab13869. Can you please tell me how your lysate was prepared? Would you be able to send me an image (jpg file) of your blot? This will help to give me a better i...