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Surface Reactions in a Biosensor

Application ID: 10428

A flow cell in a biosensor contains an array of micropillars. The curved side of the pillars are coated with an active material that allows for the selective adsorption of analyte species in the sample stream. The adsorbed species produce a signal that is dependent upon the local concentration at the pillar surfaces. This example investigates the surface concentration distribution in the cell while an analyte pulse is transported through it. It also studies the effect of a quenching surface reaction where adsorbed species are converted into an inactive state. The model illustrates how to use the Surface Reactions interface while coupling mass transport in a fluid stream with chemical reactions that occur on a surface.