Play Webinar

Title: FPGA Accelerator for Genome Aligner - ReneGENE

Description: Abstract:
Aldec industry partner, ReneLife introduces its proprietary core technology, ReneGENE, for fast and accurate alignment of short reads obtained from the Next Generation Sequencing (NGS) pipeline. The technology, devoid of heuristics can precisely align the DNA reads against a reference genome at a single nucleotide resolution. As genomics permeates the entire landscape of biology, including biomedicine and therapeutics, ReneGENE creates a genomic highway that significantly contributes to reduce the time from sample to information without compromising on accuracy, critical for lifesaving medicare applications, biotechnology product development and forensics.

In this webinar, we present AccuRA, a high-performance reconfigurable FPGA accelerator engine for ReneGENE, offered on Aldec HES-HPC™ for accurate, and ultra-fast big data mapping and alignment of DNA short-reads from the NGS platforms. AccuRA demonstrates a speedup of over ~ 1500+ x compared to standard heuristic aligners in the market like BFAST which was run on a 8-core 3.5 GHz AMD FX™ processor with a system memory of 16 GB. AccuRA employs a scalable and massively parallel computing and data pipeline, which achieves short read mapping in minimum deterministic time. It offers full alignment coverage of the genome (million to billion bases long), including repeat regions and multi-read alignments. AccuRA offers a need-based affordable solution, deployable both in the cloud and local platforms. AccuRA scales well on the Aldec platform, at multiple levels of design granularity.