The
Common Cause of Parkinson’s,
Alzheimer’s, Autism and Chronic
Fatigue.
By William Wong ND, PhD, Member World
Sports Medicine Hal of Fame

The road to discovery is long and winding.
Some of its paths lead to dead ends,
some of its paths curve round and round
until they lead to truth. The paths trod
by those seeking the cause and then a
cure for the ills that effect the brain
are no different.

In the search for the root cause of
Alzheimer's many degenerative changes
in the brain of its victims have come
to light: protein cross linking short
circuiting nerve transmission, aluminum
shards in DNA strands, decrease in neurotransmitters,
the shrinking of the brain due to loss
of its fat content (the brain is 70%
cholesterol), but all of these factors
are the results of the condition and
not its direct cause. It is now known
that moderate inflammation, not enough
to be called Enchaphilitis, but enough
to have been medically detected, is the
root cause of the condition. (1).

With Parkinson’s patients a part
of the brain called the Substancia Nigra
dies off. This vital part of the brain
makes a substance called Dopamine. It
is dopamine that connects the brain to
the body. As dopamine levels decrease
while the Substancia Nigra dies off,
slowly the control the brain exerts over
the body diminishes. So essential is
dopamine that doctors can tell a “pre
morbid” (just before death) condition
by monitoring blood levels of dopamine.
Three days after the last drop of dopamine
is made by the brain the person dies!
A link between sub clinical brain inflammation
and Parkinson’s has just been found!
(2).

What do these two dreaded and deadly
conditions have to do with Chronic Fatigue?
Plenty. Chronic Fatigue is actually a
name for what the disease brings. Only
in Europe is a true name for Chronic
Fatigue used: Myalgic Enchaphilitis or
Brain Swelling caused Muscle Pain. With
CF patients there is a brain swelling
that triggers the rest of the disease.
CFS typically has many things attributed
to being the root cause of the disease
from Mononucleosis (Epstein Barr Virus),
to Post Polio Syndrome in those of us
that received the live Sabin polio inoculation.
The Mono, initial Polio and Post Polio
all have a brain inflammation associated
with the condition.

Autism has been found to be due to a
brain inflammation. (3). The root cause
of this inflammation is under heated
debate due to the liability implications
involved. Many docs think it's from the
mercury in childhood inoculations, each
shot having 5 times the OSHA stated standard
for toxic levels for mercury. Multiply
5x the toxic levels by the number of
shots administered and you have quite
a heavy load of mercury in an infants
brain. (Flu shots for seniors have the
same mercury preservative and some docs
have been saying that any senior taking
5 or more flu shots is sure to get Alzheimer's)!
Other docs think the inflammation stems
from the viruses in the infant vaccines
themselves most of which are weakened
(attenuated) versions of a live virus,
for example the Sabin oral polio vaccine
is a live vaccine and all virus we are
exposed to will stay in the body for
life. Most conventional docs think Autism
just happens. It needs to be remembered
that there was no such thing as Autism
or any condition close to it before childhood
inoculations were invented.

A study published in the Oct. 2003 issue
of the Townsend Newsletter for Doctors
said that the use of systemic enzymes
could control the process of autism decreasing
its behavioral symptoms and though the
study has some erroneous notions as to
the function of systemic enzymes, the
test subjects all did better taking the
enzymes. This was due not to what they
attributed the final effects to but to
the anti inflammatory effect of the enzymes.

In all people as we increase in age
we increase the chronic inflammation
we carry internally. Medicine has now
come to realize that internal inflammation
is the root cause of everything from
heart and vascular disease to diabetes
and cancer. Why does inflammation increase
as we age? In our youth part of the feeling
of invincibility we possessed came from
our bodies ability to fight off the natural
results of play and effort and inflammation,
with its own unique anti inflammatory
substances: the proteolytic enzymes our
pancreas makes. The pancreas is part
of the exocrine system along with our
sweat, salivary and tear glands. It is
a gland that makes digestive juices which
contain enzymes as well as the very essential
insulin we need to be able to use sugar
for energy.

As we age our production of proteolytic
enzymes decreases (4). There are only
two products the body makes finite amounts
of dopamine and proteolytic enzymes.
Half of a persons production of proteolytic
enzymes are used up by the age of 25,
that’s part of the reason we feel
invincible at that age - our own enzymes
are controlling inflammation. By 27 our
bodies figure out that if we maintain
that level of enzyme output we’d
be dead by the time we got to forty.
Physiology teaches that old age begins
at 27 and lack of enzymes are the reason
why! So the body begins to dole out the
enzymes with an eyedropper instead of
with a tablespoon to stretch out the
store of enzymes for as long as we can
and it is the downturn in enzyme availability
that causes an increase in inflammation
as proteolytic enzymes are the bodies
first line of defense against inflammation.
(4).

From 27 onward the markers for inflammation
C-Reacitve Protein and Homocystine increase
demonstrating an increase in inflammation
inside of the body. Inflammation is a
reaction to over work, stress, over exercise,
over use and injury in both micro trauma
and macro trauma. Some nutritional gurus
have tried to lower CRP and Homocystine
levels through B vitamin and amino acid
supplementation but all they have managed
to do is tear down the road signs and
leave the road. None of the nutrients
used to lower CRP and Homocystine is
anti inflammatory so as a result the
markers to warn about inflammation are
gone but the inflammation has stayed.
A highway without road signs still leads
to the same place. (5).

Long term use of the standard drugs
for fighting inflammation, i.e. cortico
steroids and Non Steroidal Anti Inflammatory
Drugs (NSAID’s) are worse than
the inflammation they are trying to stop.
Guaranteeing an earlier death. New research
findings have stopped the use of cortico
steroids against brain inflammation in
head injury patients due to the fact
that such patients treated with the cortisone
die at a faster rate than those not treated
with the drug! (6). Besides, the long
term side effects of steroid use, the
water gain, moon face, thinning/tearing
skin, osteoporosis, bursa tissue death
etc. make these drugs unsuitable for
daily long term use. And as to the NSAID
drugs these already kill 18,000 to 22,000
a year from their kidney failure, intestinal
hemorrhage and liver failure side effects
just from regular use. (7). The Cox 2
NSAID Vioxx itself killed 39,000 people
and gave another 159,000 heart attacks
and strokes! The other Cox 2 drugs have
been shown to have the same potential
for creating heart and vascular inflammation,
yes inflammation. Imagine an anti-inflammatory
drug that causes inflammation - and the
egg head chemists and MD’s in these
drug companies promised the Cox 2 drugs
would be completely side effect free
when the drugs were first introduced.
That claim lasted all of 3 weeks as Celebrx
had killed 11 patients from side effects
in it’s first 21 days of use! (8).
So the NSAID drugs are not the way to
go either as here again the regular even
low dose use of these drugs can have
lift threatening side effects.

Recently in an effort to broaden the
use of the anti cholesterol drugs, statins
have been researched as anti inflammatory
drugs. It must be said that the side
effects of the statins have caused Dr.
Graham of the US FDA to call them the
next Vioxx. Statin drugs create liver
toxicity, neurological problems and kidney
failure via the horrible disease Rhabdomyosis,
a condition where the muscles literally
melt away and clog the kidneys causing
them to fail. Death by kidney failure
is not painless or pretty! The use of
statins against inflammation would definitely
be a case of the cure being worse than
the disease, and more life threatening.

The only anti inflammatory substances
that are safe to take long term are systemic
enzymes. They completely lack toxicity
as they have no LD-50 and are safe at
any level of ingestion. Systemic enzymes
have been used in Germany and Central
European conventional medicine for going
on 60 years and in Japan of 3 decades.
there are over 200 peer reviewed studies
confirming not only the absorption of
orally ingested enzymes but also confirming
their therapeutic effects. (www.enzymescience.com).
Against inflammation, systemic enzymes
act not as cortico steroids, Cox 1 inhibitors
or Cox 2 inhibitors do but they work
on a completely different pathway of
action which is one of the reasons they
are side effect free. (See chart below).

Of systemic enzymes not all are created
equal. While preparations may seem to
have the same enzyme components and claims
can be made as to the enzymatic action
of particular components, not all of
the same name enzymes have the same action.

Systemic enzymes give people a way to
address long term chronic inflammation
in a manner that will not create short
or long term problems, side effects or
early death. It does a patient no good
if the method of dealing with a chronic
inflammation shortens the life by it
side effects.

PS: After writing this article news
releases of new studies implicating brain
inflammation as being involved in mental
depression were released. More fuel for
the fire.

How Systemic
Enzymes Fight Inflammation

by: Dr. V. Patki, Exclzyme EN, clinical
Efficacy

NAME: Dr.
VAJAYANTI PRABHATKUMAR PATKI

M.B.B.S.

M.D. Clinical Pharmacology

EXPERIENCE:
• Prof & Head Of Dept. Clinical
Pharmacology J.J. Hospital & Grant
Medical College Mumbai till 1999
• Prof & Head Of Dept. Clinical
Pharmacology M.G.M. Medical College Aurangabad
from 1999 to 2000
• Presently working as Prof & Head
Of Dept. Clinical Pharmacology Yerala
Medical and dental College, Kharghar, Navi
Mumbai
• More than 100 National & International
Publications in area of clinical Pharmacology.

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