Pregame notes (updated): Crabtree not making season debut tonight; no surprises among inactives

Michael Crabtree won’t make his season debut tonight but the 49ers are expected to activate the wide receiver Tuesday, his final eligible day on the physically-unable-to-perform list.

General manager Trent Baalke said the 49ers were considering several options to create a spot for Crabtree on the 53-man roster, noting that Monday night’s game could impact that decision.

Crabtree tore his right Achilles on May 21 and returned to practice three weeks ago. He participated in a light workout before Monday’s game, running routes and catching passes in grey sweats.

– Cornerback Tarell Brown (ribs) will miss his first game since 2010 but he is not a candidate for injured reserve. Brown likely will return to action Oct. 8 against the Seattle Seahawks. He didn’t practice last week and was ruled out Saturday.

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– Left guard Mike Iupati’s left-knee sprain is forcing him to miss the first game of his career. Adam Snyder is starting in his place, and the offensive line’s reserves are Daniel Kilgore and Joe Looney, a 2012 fourth-round draft pick who suited up for the first time in his career.

– With Ray McDonald sidelined a straight game because of a left-ankle sprain, Demarcus Dobbs will start in his place at left defensive tackle.