1) In the book Be More Chill by Ned Vizzini, a "squip" is a tiny microcomputer that is ingested in pill form and travels to your brain, where it gives you instructions on how to be cool and/or popular. No such techonology yet exists (stuff somewhat similar in concept to this is being developed, though).
The squip is deactivated/destroyed by drinking Mountain Dew Code Red, the short-lived, highly caffenated Mountain Dew spinoff.

2)Originally, this idea was part of Ned Vizzini's largely sucessful (in some places, anyway), campaign to draw attention to his book, Be More Chill.
The campaign was based around the use of stickers that said "SQUIP? Google it.", which fans were encouraged to get for free off of his website and stick wherever they could.
As a result, many people did Google squip, and in the process stumble upon the book.

1) Some people really do wish they could have a squip.
2) "SQUIP? Google it."