This is a multicentric randomized phase III trial comparing conventional radiotherapy with concomitant chemotherapy versus accelerated radiotherapy with concomitant chemotherapy versus very accelerated radiotherapy in patients with stage III-IV head and neck squamous cell carcinoma. The main end point is the event free survival.

Renal/liver/cardiac functions and blood counts compatible with the use of paraplatin and 5-FU

Informed consent signed

Exclusion Criteria:

Distant metastasis

Contra-indication to concomitant chemotherapy

History of cancer

History of head and neck radiotherapy

Contacts and Locations

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Please refer to this study by its ClinicalTrials.gov identifier: NCT00158652