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ABSTRACT:The ethno-botany of medicinal plants is known as “Ethno- medicine. The importance scope and implications of ethno-medicine have been expanding throughout the world at a very fast rate. The present work deals with medico- ethno-botanical plants of central Bundelkhand region of M.P. The people of central region play an important role to concern the plant biodiversity by their therapeutic use of medicinal plants. The present study shows the area climate, vegetation and tribal people and their life style of central region of M.P.