Illinois' Nnanna Egwu grabs a rebound in front of Indiana's Cody Zeller (40) during the first half of an NCAA college basketball game at Assembly Hall in Champaign, Ill., on Thursday, Feb. 7, 2013. (AP Photo/John Dixon)

CHAMPAIGN, Ill. — Tyler Griffey made an uncontested layup at the buzzer off a baseline inbounds pass and Illinois beat No. 1 Indiana 74-72 on Thursday night, the fifth straight week the nation’s top-ranked team has lost.

The Illini (16-8, 3-7 Big Ten) trailed 41-29 at halftime and by double digits for most of the second half before closing the game on a 13-2 run over the final 3:36.

With the score tied, Indiana’s Victor Oladipo turned the ball over and recovered to block a breakaway layup by D.J. Richardson out of bounds with less than a second to play.

Griffey, who was open after setting a screen, took the inbounds pass from Brandon Paul with .9 seconds left and gently laid the ball into the basket.

Hundreds of Illinois students rushed the court.

The upset ended a three-game losing streak for Illinois.

The Hoosiers (20-3, 8-2) took over the top spot in The Associated Press’ Top 25 on Monday.