A year-long government investigation has found widespread use of banned drugs in Australian professional sport and links with organised crime. The Australian Crime Commission released the findings of a 12-month investigation into the integrity of Australian sport and the relationship between professional sporting bodies, prohibited substances and organised crime.

The findings are shocking and will disgust Australian sports fans.

It said the links may have resulted in match-fixing and fraudulent manipulation of betting markets - and it was hopeful criminal charges would be laid.

The key findings of the investigation identified widespread use of prohibited substances including peptides, hormones and illicit drugs in professional sport.

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It said that in some cases players were being administered with substances that have not yet been approved for human use.

The ACC also identified organised crime identities and groups that were involved in the distribution of PIEDS (Performance and Image Enhancing Drugs), to athletes and professional sports stars.

The ACC report noted increasing evidence of personal relationships of concern between professional athletes and organised criminal identities and groups.

‘‘The ACC has found that professional sport in Australia is highly vulnerable to infiltration by organised crime. Multiple athletes from a number of clubs in major Australian sporting codes are suspected of currently using or having used peptides,’’ Justice Minister Jason Clare said in a statement.

"The findings are shocking and will disgust Australian sports fans," he said.

"It's cheating...but it's worse than that. It's cheating with the help of criminals.''

Mr Clare said one possible case of match-fixing was already under investigation, though he did not identify the sport.

He said that the evidence to date indicates that it is not the majority of athletes who are taking banned substances.

The investigation had also found organised criminals had been involved in the distribution of drugs. "This is particularly serious," he said.

Former Australian Sports Anti-Doping Authority boss Richard Ings said Australians had been in denial about sports doping here for to too long.

‘‘This is not a black day in Australian sport, this is the blackest day in Australian sport," he said.

The report concluded that some coaches, sports scientists and support staff of elite athletes have orchestrated and/or condoned the use of prohibited substances.

Some sports scientists have indicated a willingness to administer substances to elite athletes which are untested or not yet approved for human use.

Sports Minister Kate Lundy said "we must remain vigilant" to fight the challenges to sports integrity.

"If you want to dope and cheat, we will catch you," she said. "If you want to fix a match, we will catch you."

Senator Lundy told reporters in Canberra that the government and Australia's major sports codes were committed to eradicating doping in sport.

She said that professional sports codes had agreed to establish integrity units and would cooperate fully with ASADA and law enforcement agencies in a joint investigation.

She added that they would also call on their athletes who had doped to come forward - "this could possibly reduce their sanctions."

''Today is about the integrity of sport in Australia,'' Senator Lundy said.

Co-operate with ASADA and law enforcement agencies in a joint investigation.

Call on their athletes to come forward and own up to wrongdoing and co-operate with investigators to possibly reduce sanctions.

Enact a multi-code policy to share information and implement doping sanctions across codes.

Have zero tolerance for any support staff involved in peddling inappropriate substances and help ensure they are not employed in other codes.

AFL boss Andrew Demetriou said he was shocked by the findings, and said he did not know how many AFL clubs were involved.

He said the AFL's investigation had already begun and that the league was working with ASADA.

NRL chief executive David Smith, who was in Canberra for the report's release, said: "we need to be strong."

Australian Rugby Union said it had set up an integrity office and hired an Australian Federal Police detective to look into drugs in its code. Over 2011 and 2012, it had prosecuted four cases.

Rugby Union boss Bill Pulver called the report a "very timely wake-up call", saying he had been aware of the issue of performance enhancing drugs but less aware of the links to organised crime.

Cricket Australia CEO James Sutherland said his organisation was "as confident as we can be" that there was no match-fixing in the Big Bash.

"We have out own integrity unit that has surveillance activities over all of the Big Bash league matches."

Opposition Leader Tony Abbott - an avid sportsman - told reporters in Queanbeyan that he was dismayed by the revelations about integrity in sport.

''Obviously, I'm dismayed at the revelations today,'' he said on Thursday.

Mr Abbott said the Coalition would work with the government to deal with the problems.

''We want sport to be clean and fair,'' he said.

When asked if he supported tough, new regulations, Mr Abbott said he would wait to see what the government proposed. ''But in principle, yes,'' he said.

Victoria Police deputy commissioner Graham Ashton said the force had asked for legal advice about how it could be involved.

Mr Ashton said there was a grey area in dealing with performance enhancing drugs and Victoria Police had sought legal advice on the levels of criminality involved.

He said he hoped for better communication between police and sporting codes as a result of the report.

Independent SA Senator Nick Xenephon has called for an immediate suspension on sports-betting following the "damning" findings of the ACC report.

“These extraordinarily findings require an urgent response to protect the integrity of sporting codes that millions of Australians love,” he said.

Senator Xenophon also renewed his calls for the major parties to support his 2011 Bill for a permanent ban on micro-betting – such as ball-by-ball betting – because of the increased potential of corruption.

“Micro-betting gives macro opportunities for corruption."

This comes as the Senate passed a motion by Greens senator, Richard Di Natale, to conduct an inquiry into the impact of advertising and promotion of gambling on sport.

The inquiry - which was in the pipeline before the ACC report - is due to report by May 16.

“You can’t watch a sporting event with your kids without being bombarded by betting odds and gambling adds," Senator Di Natale said in a statement.

“Not only do we risk undermining the integrity of sport, we risk creating another generation of problem gamblers.”

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AFL clubs will have their staff audited, sports science staff registered and be instructed to undertake mandatory reporting of any doping issue in an attempt to stamp out widespread illegal drug use across the league.