Cancer classification guidelines putting countless in harms way

A devastating report commissioned by the National Cancer Institute reveals that our 40-year long ‘War on Cancer’ has been waged against a vastly misunderstood ‘enemy,’ that in many cases represented no threat to human health whatsoever.

A National Cancer Institute commissioned panel’s report published in JAMA online confirmed that we all – public and professionals alike – should stop calling low-risk lesions like DCIS and high-grade prostatic intraepithelial neoplasia (HGPIN) ‘cancer.’

There are wide-reaching implications to this recommendation, including:

Millions of women in this country have been diagnosed with DCIS, and millions of men with HGPIN, and subsequently [mis]treated. Are they now to be retroactively reclassified as ‘victims’ of iatrogenesis, with legal recourse to seek compensation?

Anyone engaged in a cancer screening will now need to reconsider and weigh both the risks and benefits of such a ‘preventive’ strategy, considering that the likelihood of being diagnosed with a false positive over 10 years is already over 50% for women undergoing annual breast screening.

The burgeoning pink ribbon-bedecked ‘breast cancer awareness’ industry will be forced to reformulate its message, as it is theoretically culpable for the overdiagnosis and overtreatment of millions of US women by propagating an entirely false concept of ‘cancer.’

The practice of oncology in the United States is in need of a host of reforms and initiatives to mitigate the problem of overdiagnosis and overtreatment of cancer, according to a working group sanctioned by the National Cancer Institute.

Perhaps most dramatically, the group says that a number of premalignant conditions, including ductal carcinoma in situ and high-grade prostatic intraepithelial neoplasia, should no longer be called “cancer.”

Instead, the conditions should be labeled something more appropriate, such as indolent lesions of epithelial origin (IDLE), the working group suggests. The Viewpoint report was published online July 29 in JAMA.

Fundamentally, overdiagnosis results from the fact that screen-detected ‘cancers’ are disproportionately slower growing ones, present with few to no symptoms, and would never progress to cause harm if left undiagnosed and untreated.

As you can see by the graph above, it is the fast-growing tumors which will be more difficult to ‘detect early,’ and will progress rapidly enough to cause symptoms and perhaps even death unless treated aggressively. But even in the case of finding the tumor early enough to contain it through surgery, chemotherapy and/or radiation, it is well-known that the minority subpopulation of cancer stem cells within these tumors will be enriched and therefore made more malignant through conventional treatment. For instance, radiotherapy radiation wavelengths were only recently found by UCLA Jonnsson Comprehensive Cancer Center researchers to transform breast cancer cells into highly malignant cancer stem-cell like cells, with 30 times higher malignancy post-treatment.

What this means is that not only are millions of screen-detected abnormalities not ‘cancer’ in the first place but even those which can be considered fast-growing are often being driven into greater malignancy by the conventional chemotherapy, radiation and surgery-based standard of cancer care itself.

Our entire world view of cancer needs to shift from an enemy that “attacks” us and that we must wage war against, to something our body does, presumably to survive an increasingly inhospitable, nutrient-deprived, carcinogen- and radiation-saturated environment, i.e. Cancer As An Ancient Survival Mechanism Unmasked.

“The word “cancer” often invokes the specter of an inexorably lethal process; however, cancers are heterogeneous and can follow multiple paths, not all of which progress to metastases and death, and include indolent disease that causes no harm during the patient’s lifetime.”

We must keep in mind that this proposed redefinition of cancer is no small academic matter, but will affect the lives of millions of women. Consider that every year, approximately 60,000 women in this country are diagnosed with DCIS, a diagnosis so traumatic that it results in significant psychiatric depression 3 years after even a ‘false positive’ diagnosis. For those less fortunate women, numbering in the millions over the past 30 years, who were told they had ‘cancer’ and needed to undergo lumpectomy, radiation, chemotherapy and/or mastectomy, the NCI panel’s recommendation is a hard pill swallow after the damage has already been irrevocably done.

So, what’s the solution? There is a growing movement towards the use of thermography as a primary diagnostic tool, as it uses no ionizing radiation, and can detect the underlying physiological processes that may indicate inflammation, angiogenesis, cancer-specific metabolic changes, etc., many years before a calcified lesion would appear within an x-ray mammogram. Also, the mainstay of any truly preventive strategy against cancer is diet, nutrition, exercise and avoiding chemical and radiation exposures – the things that we can do in our daily lives to take back control of and responsibility for our health.

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