How to delete plugin from plugins on running server

Hello,
I moved from Linux to Windows and I'm finding some way to delete plugin from folder plugins while server is running? (plugin would be loaded in memory, but after /reload, it has disable)
Thanks for help!

I'd generally assume this is a truly terrible idea 99% of the time. But if you're dead-set on it.. be incredibly careful about permissions or locking down to console only.. can you imagine if a player managed to run a command and deleted your permissions plugin