In terms of the plot, New Amsterdam is primarily based on Dr. Eric Manheimer’s memoir from 2012 called Twelve Patients: Life and Death at Bellevue Hospital.

In his book, Manheimer talks about working as a doctor while battling throat cancer. While Season 1 was about his diagnosis and working at the hospital during treatment, the show will also draw on the 150 notebooks that he kept during his treatment.

While Dr. Manheimer took months off to recover, New Amsterdam won’t be showcasing Dr. Max Goodwin’s time away from the hospital.

Instead, the character will continue to work through his treatment. It’s possible that Dr. Manheimer’s personal story will change a bit during Season 2 to make his memoir more television friendly.

In addition, Janet Montgomery is also expected to return after she recently gave birth to her baby girl. Freema Agyeman, Jocko Sims, Tyler Labine, and Anupam Kher are also expected to return at the present time.