The
GRC generates a range of annotations on the reference genomes it
curates. These tracks describe the assembly of the genome, as well as quality issues with
the genome, and provides information relevant to their resolution or
planned improvement. Much of this annotation is already available via thegEVAL browser. However, the track hub allows you to view this annotation in the genome browser of your choice.

The individual tracks currently available are:

Genome issues under review by the GRC

Genomic regions defined by the GRC

Alignments between the primary assembly and alternate loci or patches

Clone sequence anomalies

Human regions with clones from the CHORI-17 library (CHM1tert)

These tracks are updated on a weekly basis. We will be adding to this range of information as time goes on.

How does this look?

Here's how this data looks in Ensembl:

Here's how it looks in UCSC:

What is a track hub?

A
track hub is a means of attaching multiple annotation tracks to a
genome browser via a single URL. Full documentation on track hubs is
availablehere.

Tuesday, October 14, 2014

The first patch release for the GRCh38 reference assembly is now available. The GRCh38.p1 release includes 16 scaffolds: 13 FIX patches and 3 NOVEL patches. The FIX patch scaffolds correct existing assembly sequences, while the NOVEL patch scaffolds provide new alternate sequence representations. You can download the GRCh38.p1 assembly, including the alignments of the patches to GRCh38, from the GenBank FTP site: ftp://ftp.ncbi.nlm.nih.gov/genomes/all/GCA_000001405.16_GRCh38.p1/.