Browse our CFLAR Proteins (CFLAR)

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CASP8 and FADD-Like Apoptosis Regulator Proteins (CFLAR)

On www.antibodies-online.com are 12 CASP8 and FADD-Like Apoptosis Regulator (CFLAR) Proteins from 7 different suppliers available. Additionally we are shipping CFLAR Antibodies (272) and CFLAR Kits (4) and many more products for this protein. A total of 310 CFLAR products are currently listed.

The results reveal a novel inhibitory role of c-FLIP in myeloid cell activation and demonstrate the unexpected anti-inflammatory activity of c-FLIP.

Upon starvation, c-Flip affects lipid accumulation, ER stress and autophagy, thereby pointing to an important role of c-Flip in the adaptive response and ER stress response programs under both normal and pathological conditions.

Intracellular remodeling with the overexpression of c-FLIP(S/L) in xenograft cells may avoid innate cellular attacks against xenografts and facilitate long-term xenograft survival.

Overexpression of c-FLIP in xenograft cells may prevent innate cellular attacks against xenografts opening the window of opportunity for long-term xenograft survival.

CFLAR Protein Profile

Protein Summary

The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.