The actresses query their boss for THR's Power Showrunners Issue

This story first appeared in the Oct. 17 issue of The Hollywood Reporter magazine.

Anna Faris: When were you first inspired to create the show?

Chuck Lorre: I started the process in 1993 when I went to Elgin, Illinois, to research single moms. I was struck by the impossible nature of raising children, working and trying to have a life. What came out of that was one season of Grace Under Fire. Then I left that show for reasons we don't have to go into now.

Janney: What is your secret to making a show about characters who are struggling with addiction funny?

Lorre: There's an unspoken contract with the audience that promises comedy. But you can't be glib about difficult subjects because that's disrespectful. I think these characters represent hope for one another. The tragedy of the past is in their rearview mirror, which gives you a chance to lighten the mood.

Lorre: Yes. It tore me up! It hit me hard, when Violet [Sadie Calvano] gives the baby up. I've spent 25 years chasing laughs and there I am, sobbing and trying to not let anybody see! It's a good litmus test when you feel that deeply about fictional characters. I remember when we shot it, I was dry as could be. As soon as I was in editing, I started crying.

Faris: We talk a lot about how great it is to have such a densely packed show. We do so much in one episode.

Lorre: That's something we talk about in the writers room, too. "Let these great actors act and let the comedy come from that as opposed to writing jokes."

Janney: What's the nicest feedback you've gotten about the show from the outside world?

Lorre: I don't go on the street! I'm a very indoor cat. I'm terrified of social media. I'm just getting the hang of emails.

Farris: Well, feedback to me has been incredible. I've never done anything that touches people like this.

Lorre: That's great. A few people have told me it's not just something they watch — they've personalized it, which is a dream come true to hear.