Doug Engelbart defined Collective IQ as a measure of how effective people are at addressing complex, urgent challenges collectively. As the rate and scale of challenges we face in the world increase exponentially, we must find exponentially smarter, faster ways of working together to solve important problems. In other words, we must proactively boost our Collective IQ... (read more). Here Doug's daughter Christina, Executive Director of the Doug Engelbart Institute, writes about all things Collective IQ and Doug Engelbart, and goings on at the Institute.

Join the NMC and our panel of Increasing Focus on Open Content thought leaders on Wednesday, October 1 at 8am PT / 10am CT/ 11am ET.

The movement toward open content reflects a change in the way educators and scholars are conceptualizing education. Information is everywhere now; the challenge is to make effective use of it. Often mistaken to simply mean “free of charge,” advocates of openness have worked toward defining “open” more broadly — not just free in economic terms, but also in terms of

A major challenge of systems biology is understanding how phenomena at the cellular scale correlate with activity at the organism level. A concerted effort has been made especially in the brain, as scientists are aiming to clarify how neural activity is translated into consciousness and other complex brain activities.

One example of the technologies needed is whole-brain imaging at single-cell resolution. This imaging normally involves preparing a highly transparent sample that minimizes light scattering and then imaging neurons tagged with fluorescent probes at different slices to produce a 3D representation. However, limitations in current methods prevent comprehensive study of the relationship. A new high-throughput method, CUBIC (Clear, Unobstructed Brain Imaging Cocktails and Computational Analysis), published in Cell, is a great leap forward, as it offers unprecedented rapid whole-brain imaging at single cell resolution and a simple protocol to clear up and make the brain sample transparent, is based on the use of amino-alcohols.

In combination with light sheet fluorescence microscopy, CUBIC was tested for rapid imaging of a number of mammalian systems, such as mouse and primate, showing its scalability for brains of different size. Additionally, it was used to acquire new spatial-temporal details of gene expression patterns in the hypothalamic circadian rhythm center. Moreover, by combining images taken from opposite directions, CUBIC enables whole brain imaging and direct comparison of brains in different environmental conditions.

CUBIC overcomes a number of obstacles compared with previous methods. One is the clearing and transparency protocol, which involves serially immersing fixed tissues into just two reagents for a relatively short time. Second, CUBIC is compatible with many fluorescent probes because of low quenching, which allows for probes with longer wavelengths and reduces concern for scattering when whole brain imaging while at the same time inviting multi-color imaging. Finally, it is highly reproducible and scalable. While other methods have achieved some of these qualities, CUBIC is the first to realize all.

CUBIC provides information on previously unattainable 3D gene expression profiles and neural networks at the systems level. Because of its rapid and high-throughput imaging, CUBIC offers extraordinary opportunity to analyze localized effects of genomic editing. It also is expected to identify neural connections at the whole brain level. In fact, last author Hiroki Ueda is optimistic about further application to even larger mammalian systems. “In the near future, we would like to apply CUBIC technology to whole-body imaging at single cell resolution”.

intelligence is not just something that happens inside individual brains. It also arises with groups of individuals. In fact, I'd define collective intelligence as groups of individuals acting collectively in ways that seem intelligent. By that definition, of course, collective intelligence has been around for a very long time. Families, companies, countries, and armies: those are all examples of groups of people working together in ways that at least sometimes seem intelligent. (..) What's new, though, is a new kind of collective intelligence enabled by the Internet.

Diversity begets creativity—in this seminar we tap the amazing power of swarm creativity on the Web by studying and working together as Collaborative Innovation Networks (COINs). As interdisciplinary teams of MIT management, SCAD design, University of Cologne informatics, and Aalto University software engineering students we will explore how to discover latest trends on the Web, and how to make them succeed in online social networks. We study a wide range of methods for predictive analytic

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