KravprofilThe increasing prevalence of type 2 diabetes (T2D) in western societies is closely associated to sedentary life-styles, excessive consumption of hyper-caloric food products and obesity. Metabolic imbalances and diabetes impact the central nervous system (CNS). In this context, the initial events contributing to the loss of metabolic control involve derangements of hypothalamic functions, and long-term metabolic imbalance contributes to brain dysfunction. Our lab is interested in the prevention of metabolic and functional alterations that occur in the CNS, with particular focus on rescuing the control of energy homeostasis, and on the recovery of cognitive ability.

The "Diabetes and Brain Function" lab is looking for a post-doctoral researcher to investigate the impact of diabetes on cerebral metabolism and function.

Work tasks- keep up to date with the literature in the research field;

- actively conduct laboratory research and participate in collaboration projects;

- other duties assigned ad hoc, which may include attending meetings, participate in workshops, and carrying administrative tasks related to the research

The work will be focused on preclinical models of diabetes, and will involve molecular biology methods, behaviour studies on rodents, and state-of-the-art magnetic resonance (MR). Non-invasive MR experiments till be conducted in collaboration with the Lund University Bioimaging Center (LBIC). Testing neuroprotective and reparative strategies for improving cerebral function in diabetes as envisaged.

Qualification requirements- education at PhD level in the realm of biochemistry and/or pharmacology;

- research experience abroad;

- experience of working on mouse models, cell biology research, and biochemistry methods;

- research experience on regulation of whole body glucose homeostasis, and on cellular pathways involved in oxidative stress, inflammation and cell death;

- track record of high-profile publications on diabetes research;

- demonstrated teaching and mentoring experience;

- fluency in English, and excellent writing and communication skills;

- ability to work both independently and in a multidisciplinary team;

- motivation to pursue the research goals of our lab

Applications are to be submitted in English and must include: 1) a motivation letter explaining the applicant's match to the position, and how the applicant's research goals are in line with those of the lab.; 2) detailed CV and list of published articles; 3) names and contacts of 3 references.