Novartis drug helps in serious childhood arthritis

The findings were presented at the European Pediatric Rheumatology Congress in Bruges, Belgium. John Hohneker, head of development for integrated hospital care at Novartis, told Reuters the data was "outstanding."

Pierre Quartier of the Necker-Enfants Malades Hospital, Paris, who was one of the investigators on the study, said it suggested ACZ885 could become an important treatment option for children with SJIA.

Novartis plans to file for regulatory approval of the drug in SJIA in 2012 in both the United States and Europe, based on data from this and a second Phase III trial, which will be presented later this year.

Novartis is banking on new products to help it offset patent losses on big sellers such as blood pressure treatment Diovan. Expectations for Ilaris, however, are relatively modest in the wake of the disappointment over its potential use for gout. Analysts, on average, forecast sales of $412 million in 2016, according to Thomson Reuters Pharma.

Researchers said the SJIA study did not uncover any new safety findings and no patients had to discontinue treatment due to adverse events. The study met all its primary and secondary endpoints.

SJIA affects less than one child per 100,000. It causes inflammation affecting the whole body, which can involve skin rash, fever, joint pain and swelling.