Sleep deprivation was found to affect many organs including the immune system and predisposing for various health consequences including diabetes hypertension infections and increase in neoplastic diseases.

Subjects will be evaluated for immune parameters in peripheral blood test following a regular nigh sleep and compared with a test performed following a night shift in which they slept less than 3 hours.

Blood tubes will be tested for T cell markers, serum cytokines levels, and other immune parameters by western blots.

The first tube will be tested on the day of experiment.

The second tube will kept in the lab and will be tested 24 hours later.

The third tube will be kept in the pocket of the subject and be tested 24 hours later.

The fourth tube will be kept in the pocket of another subject and will be tested 24 hours later.

The subject will be tested again following 24 hours.

Each subject will be tested twice following a regular 6-8 hours of sleep, and following an on call duty in which he slept less than 3 hours.

Eligibility

Ages Eligible for Study:

18 Years to 40 Years (Adult)

Genders Eligible for Study:

Both

Accepts Healthy Volunteers:

Yes

Sampling Method:

Probability Sample

Study Population

Medical residnets

Criteria

Inclusion Criteria:

Male and female ages 18-40 signed confirmed consent no evidence of chronic disease or chronic medications

Exclusion Criteria:

Any type of acute infection or other acute illness

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01930279