SEP Client for Exchange

Am planning to install for exchange server, but worry if the real time scan degrade performance of mail service. To install client in exchange, do I need to set scan exclusion to certain path or folder ?

the product is fully compatible with Exchange. You may deploy the product to exchange server without any second thoughts. As Tony said, there auto exclusion in SEP, that will take of Exchange exclusions. And I felt that the following document will be of great help to you.