Background*

Mr. Santo J. Costa, also known as Sandy, J.D., has been a Consultant of Quintiles Transnational Corp. since June 2001. Mr. Costa serves as an Attorney with Maupin Taylor P.A. of Raleigh, North Carolina. He serves as Of Counsel to the law firm of Maupin Taylor & Ellis. He has been Of Counsel to the law firm of Smith, Anderson, Blount, Dorsett, Mitchell and Jernigan, LLP since August 2007. He served as an Executive Officer of EBM Solutions, Inc. He was U.S. Area Counsel ... for Merrell Dow Pharmaceuticals. He served as an Of Counsel at the law firm of Williams Mullen from June 2001 to August 2007. He has more than 35 years of experience. He has a broad operational leadership experience in the pharmaceutical and clinical services industries, including relevant legal, regulatory, governance and policy expertise. He also has extensive experience as a public company executive and board member in the pharmaceutical and biotechnology industries. He started his career as Food and Drug Counsel for Norwich Eaton Pharmaceuticals. From 1994 to 2002, Mr. Costa held various positions at Quintiles Transnational Corporation. He served as the President and Chief Operating Officer at Quintiles Transnational Corporation from April 1994 to November 1999; Senior Consulting Executive from June 2001 to December 2002. He was employed at GlaxoSmithKline plc. He was employed by Glaxo Inc., where he served as Senior Vice President of Administration and General Counsel of Glaxo Inc. from 1986 to 1993. He served as the Non-Executive Chairman of Alchemia Limited from March 1, 2014 to June 10, 2015. He served as Chairman of Labopharm Inc. from May 4, 2006 to 2011. He serves as Chairman of the Advisory Board of Capital Analytics, Inc. He serves as Chairman of Dermatrends Inc. He served as Chairman of NeuroMedix Inc. from 2005 to 2007. He served as the Chairman and Director of BioPheresis Technologies, Inc. He chaired the law section of the then Pharmaceutical Manufacturing Association. He served as Vice Chairman of Quintiles Transnational Corporation from November 1999 to June 2001. Mr. Costa has been a Director of Cytokinetics, Incorporated since November 1, 2010, Labopharm Inc. since March 2, 2006, and Digilab, Inc. since April 15, 2010. Mr. Costa serves as a Director of Yonkers Industries Inc., Dermatrends Inc. and Digiscript Inc. He serves as Director of a number of health sciences companies. He serves as a Member of the Board of Advisors of AM Pappas & Associate. Mr. Costa serves as a director of the Food and Drug Law Institute Advisory Board. He sits on the Board of Advisors of the Duke Cancer Patient Support Program Advisory Board, the Duke University Medical Center Board of Visitors, and the Duke Brain Tumor Advisory Board. He served as a Director at Alchemia Limited. Mr. Costa sits on the boards of several pharmaceutical and healthcare companies and has lectured on food and drug law issues and a wide variet y of legal and policy issues affecting the pharmaceutical industry. He served as a Director of Osi Pharmaceuticals Inc. from June 14, 2006 to June 3, 2010. He served as a Director of Biovest Corp. I from March 8, 2010 to March 2013. He served as a Director of CV Therapeutics from 2001 to 2009. He served as Director of Gilead Palo Alto, Inc. since May 2001 and Pilot Therapeutics Holdings Inc. since January 2000. He served as Director of NeuroMedix Inc. until May 2007. He served as a Director of Constella Group, Inc. (also known as Constella Group, LLC) since November 16, 2005. Mr. Costa served as Director of NPS Pharmaceuticals, Inc. from 1995 to May 22, 2007. He served as Director of Quintiles Transnational Corp. from April 1994 to June 2001. He served as a Director of Glaxo Inc. He served as a Director of Ribapharm Inc. since 2003. He is a Member of the North Carolina Bar Association, the New York Bar and the Ohio Bar. Mr. Costa is an adjunct professor in the clinical research program at the Campbell University School of Pharmacy. He holds a B.S. in Pharmacy from St. John's University in 1968 and a Juris Doctor from St. John’s University in 1971.

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