Bono also talked Trump: "Everything's different now. The game has changed."

The Irish rockers addressed the incident on Jimmy Kimmel Live! — they chatted with the host and performed "Still Haven't Found What I'm Looking For," a classic from their Joshua Tree album, which turns 30 this year and is being commemorated with a major tour.

Bono said this of the terrorists who carried out the Manchester Arena bombing: "They hate music, they hate women, they even hate little girls. They hate everything that we love. And, you know, the worst of humanity was view in Manchester last night. And so was the best as people took perfect strangers into their hands and queued up for blood banks. Manchester has an undefeatable spirit, I can assure you.” The band posted the interview from its official Twitter account with the hashtag #Manchesterstrong.

U2 knows only too well this type of horror. The veteran Irish rockers were in Paris on Nov. 13, 2015, when a series of coordinated attacks occurred throughout the city, with the deadliest coming at the Bataclan theater. All told, 130 lives were lost, with 89 casualties at the Bataclan where Eagles of Death Metal had been playing. Bono went on to write a song for the capital, titled "Streets of Surrender" or "SOS."

Later on Kimmel, U2 took viewers back to a time when they ruled the world with a performance of the Billboard Hot 100 chart-topper with a gospel choir rising from the audience.

Bono also opened up about his years of working with a wide, bipartisan swath of American politicians as part of his One campaign against global poverty. However, "everything's different now. The game has changed," he said, giving props to those whose anger helped bring President Donald Trump into office while worrying that the billionaire real estate magnate has no real connection to his core demo. "I don't think he's the cure for this problem. I think he might make it worse."