Sitting is pretty awful for you. We all know this. And yet, day after day, we still go to the office and spend an eight-hour (at least) stretch behind a desk. But I go to the gym most nights, you say. And, I always start the day with yoga, you protest.

Well, according to new research, those 45-minutes of intense activity won't be enough to outweigh the damages caused by a mainly sedentary lifestyle. A report published in the Annals of Internal Medicine analyzed 47 different studies and found that physical inactivity leads to premature death and disease…which, OK, we basically already knew. But the new revelation here is that a little exercise doesn’t do much to prevent health issues caused by general lack of movement.

If you’re spending 15 hours of your day sitting down and another 8 or so asleep, a few miles on the treadmill is not enough to counteract the dangers associated with long periods of inactivity including increased risk of heart disease and type 2 diabetes. Fortunately, it’s a pretty easy thing to fix. Obviously logging hours upon hours at the gym isn’t something most of us can do, but—as no-brainer as it sounds—simply moving more makes a big difference.