The acerbic, hilarious Claire Simmons becomes fascinated by the suicide of a woman in her chronic pain support group. As she uncovers the details of Nina's suicide and develops a poignant relationship with Nina's husband, she also grapples with her own, very raw personal tragedy.

Cake is the first time Jennifer Aniston is in the lead of a true drama and she has the chance to either show her acting potential or go back to comedies. Cake is also the first time Jennifer has filmed an entire film without wearing any makeup...going all natural.