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Tag: Half-life

HLP

:: DESCRIPTION

HLP is a server developed for predicting half-life of peptides in intestine like environment. It generates all possible mutants (single mutation at each position per cycle) for a peptide and predict/calculate half-life and physicochemical properties (e.g. charge, polarity, hydrophobicity, volume, pK) of mutant peptides.

PEPlife

:: DESCRIPTION

PEPlife is a manually curated database of experimentally validated therapeutic peptides and their halflives. In this database, peptides have been collected from both published articles as well as from patents.Each entry provides comprehensive information about a peptide that includes its sequence, chemical modifications incorporated, biological activity possessed, its half-life, the assay used to determine its half-life etc.

PlifePred

:: DESCRIPTION

PlifePred is prediction server for predicting the half-life of peptides in blood. Users can use PlifePred to increase or decrease the half-life of their peptide by generating mutants. The server facilitates designing the half-life of a peptide by generating its mutants and predicting their half-life and physiochemical properties.The user can screen and select the peptide with suitable properties desired.

HALO 1.3

:: DESCRIPTION

HALO (Half-life Organizer) is the first software for the precise determination of transcript half-lives from measurements of RNA de novo transcription. In addition, methods for quality control, filtering and normalization are supplied. HALO provides a graphical user interface, command line tools and a well-documented Java API. Thus, it can be used both by biologists to determine transcript half-lives fast and reliably with the user interfaces provided as well as software developers integrating transcript half-life analysis into other gene expression profiling pipelines.