Fusion

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

COG7

Component of oligomeric golgi complex 7 (758 aa)

Predicted Functional Partners:

COG3

Component of oligomeric golgi complex 3 (805 aa)

0.966

COG8

Component of oligomeric golgi complex 8 (546 aa)

0.965

COG6

Component of oligomeric golgi complex 6 (681 aa)

0.959

COG2

Component of oligomeric golgi complex 2 (567 aa)

0.949

COG4

Component of oligomeric golgi complex 4 (1094 aa)

0.947

COG5

Component of oligomeric golgi complex 5 (764 aa)

0.935

COG1

Component of oligomeric golgi complex 1 (1324 aa)

0.930

EDO96072

Predicted protein (741 aa)

0.889

COPB1

Beta-cop; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (959 aa)

0.801

COPG1

Gamma-cop; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (883 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

COG1

COG2

EDP03817

EDP01935

Component of oligomeric golgi complex 1

Component of oligomeric golgi complex 2

0.957

COG1

COG3

EDP03817

EDP03370

Component of oligomeric golgi complex 1

Component of oligomeric golgi complex 3

0.924

COG1

COG4

EDP03817

EDP01627

Component of oligomeric golgi complex 1

Component of oligomeric golgi complex 4

0.925

COG1

COG5

EDP03817

EDP00378

Component of oligomeric golgi complex 1

Component of oligomeric golgi complex 5

0.919

COG1

COG6

EDP03817

EDP09132

Component of oligomeric golgi complex 1

Component of oligomeric golgi complex 6

0.918

COG1

COG7

EDP03817

EDP06912

Component of oligomeric golgi complex 1

Component of oligomeric golgi complex 7

0.930

COG1

COG8

EDP03817

EDP05807

Component of oligomeric golgi complex 1

Component of oligomeric golgi complex 8

0.934

COG1

COPB1

EDP03817

EDO97648

Component of oligomeric golgi complex 1

Beta-cop; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins

0.647

COG1

COPG1

EDP03817

EDP04926

Component of oligomeric golgi complex 1

Gamma-cop; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins

0.787

COG1

EDO96072

EDP03817

EDO96072

Component of oligomeric golgi complex 1

Predicted protein

0.894

COG2

COG1

EDP01935

EDP03817

Component of oligomeric golgi complex 2

Component of oligomeric golgi complex 1

0.957

COG2

COG3

EDP01935

EDP03370

Component of oligomeric golgi complex 2

Component of oligomeric golgi complex 3

0.959

COG2

COG4

EDP01935

EDP01627

Component of oligomeric golgi complex 2

Component of oligomeric golgi complex 4

0.988

COG2

COG5

EDP01935

EDP00378

Component of oligomeric golgi complex 2

Component of oligomeric golgi complex 5

0.929

COG2

COG6

EDP01935

EDP09132

Component of oligomeric golgi complex 2

Component of oligomeric golgi complex 6

0.954

COG2

COG7

EDP01935

EDP06912

Component of oligomeric golgi complex 2

Component of oligomeric golgi complex 7

0.949

COG2

COG8

EDP01935

EDP05807

Component of oligomeric golgi complex 2

Component of oligomeric golgi complex 8

0.953

COG2

COPB1

EDP01935

EDO97648

Component of oligomeric golgi complex 2

Beta-cop; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins

0.669

COG2

COPG1

EDP01935

EDP04926

Component of oligomeric golgi complex 2

Gamma-cop; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins

0.760

COG2

EDO96072

EDP01935

EDO96072

Component of oligomeric golgi complex 2

Predicted protein

0.913

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Network Stats

Network Stats analysis is still ongoing, please wait ...

Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: