Description: Clindamycin Hydrochloride is the hydrochloride salt form of clindamycin. It is a semi-synthetic, chlorinated broad spectrum antibiotic. Clindamycin Hydrochloride is produced by chemical modification of lincomycin. It is a derivant of Lincomycin. Clindamycin hydrochloride can be used as a solid in capsules. Clindamycin Hcl is used to treat a wide variety of bacterial infections. It is an antibiotic which works by stopping the growth of bacteria. Clindamycin Hcl treats only bacterial infections. It will not work for virus infections.

As a professional China Clindamycin Hydrochloride, Clindamycin Hcl supplier and Manufacturer, FENGCHEN GROUP CO., LTD has been supplying and exporting Clindamycin Hydrochloride, Clindamycin Hcl from China for almost 10 years.

The mechanism of Clindamycin Hcl is through the body of DNA with the bacteria nucleoprotein 50s subunits combination, Interfere the extension of peptide chains, by this way it effects bacteria protein synthesis for the sake of sterilization. Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins.

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Uses

Clindamycin Hcl or Clindamycin Hydrochloride Powder API Raw Material BP, EP, USP is popularly used to treat a wide variety of bacterial infections. It is a prevailing antibiotic which functions by stopping bacteria growth.

Clindamycin Hcl or Clindamycin Hydrochloride Powder API Raw Material BP, EP, USP only works for bacterial infections. It won’t work for virus infections. Unnecessary use or misuse of Clindamycin Hcl or Clindamycin Hydrochloride could lead to its decreased effectiveness.

Guidance:

Take Clindamycin Hcl orally with or without food. Suggested four times a day (every 6 hours), or as directed by your doctor. Take Clindamycin Hydrochloride with a full glass of water (8 ounces or 240 milliliters) unless your doctor tells you not to. Do not lie down for at least 10 minutes after taking this medication.

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Indications and Usage

There are Clindamycin Hcl or Clindamycin Hydrochloride Powder API Raw Material BP, EP, USP liquid or capsule in the market. There is another formulation gel which can be used to treat skin or vaginal infections or acne.. In some cases, it can be used to treat acne, exposure to anthrax or malaria.

The liquid form of Clindamycin Hydrochloride should be shaken before consumption to ensure the mixture is combined evenly. Clindamycin Hcl Capsules should be taken with a full glass of water to ensure that the medication begins to absorb properly. Try to take your doses around the same time every day to help keep a constant supply of the medication in your bloodstream. It is strongly not recommended that double up on doses to make up for ones you may accidently miss.

Clindamycin Hcl Side Effects

Common side effects of Clindamycin Hcl or Clindamycin Hydrochloride Powder API Raw Material BP, EP, USP include nausea, joint pain, diarrhea, abdominal pain, heartburn, vomiting, pain when swallowing, thick vaginal discharge, white patches in the mouth and burning or swelling in the vagina. These side effects are not typically severe. They will go away itself without special treatment. If these symptoms don’t go away or even get worse. Contact the doctor. Do not stop taking it unless a medical professional tells you to so you can avoid complications with your treatment from arising.

Those using clindamycin hcl to treat acne have reported dryness, burning, redness, itching or peeling on the skin. If these symptoms are severe, stop immediately.

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Clindamycin Hydrochloride--Drug Interactions

Using together with Clindamycin Hydrochloride, its the effect may change. Clindamycin Hcl or Clindamycin Hydrochloride Powder API Raw Material BP, EP, USP may interact with the following drugs and products: Clarithromycin, Erythromycin, Kaolin-pectin.

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Certificate of Analysis (Clindamycin Hcl)

Test items

Specifications

Results

Characters Clindamycin Hcl

White or practically white, crystalline powder

White crystalline powder

Identification

IR Conform
Clindamycin Hydrochloride

Conform

Solubility

Freely soluble in water, in dimethylformamide, and in methanol;soluble in alcohol; practically insoluble in acetone

Conform

Crystallinity

Conform

Conform

PH

3.0~5.5

3.9

Water

3.0%~6.0%

4.0%

Related compounds

≤2.0% clindamycin B

0.87%

≤4.0% 7-epiclindamycin

0.66%

≤1.0% any other individual related compound

0.19%

≤6.0% total of all related compound

2.2%

Residual solvents

Acetone ≤5000ppm

91ppm

Ethanol ≤5000ppm

No detected

N,N-Dimethylformamide≤880ppm

No detected

Chloroform≤60ppm

No detected

Assay Clindamycin Hcl

Not less than 800μg of clindamycin (C18H33ClN2O5S)per mg

862 μg/mg
Clindamycin Hydrochloride

Side effects of Clindamycin Hydrochloride:

There can be side effects like: 1. A change in bowel habits (especially in older adults);2.some times, mild nausea, vomiting, or stomach pain;3. joint pain may occour; 4.vaginal itching or discharge;5.mild rash or itching;6.heartburn, irritation in your throat.

If you are looking for the Clindamycin Hcl or Clindamycin Hydrochloride Powder API Raw Material CAS 21462-39-5, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.