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Genome Evolution Laboratory

We develop and apply computational and experimental tools to study the evolution of bacterial genomes. Much of our work focuses on characterizing and understanding the diversity of the Enterobacteria, a group that includes the much studied human and animal pathogens, Escherichia coli, Salmonella and Yersinia, as well as the lesser appreciated pathogens of plants, Erwinia, Pectobacterium, Dickeya and Pantoea, plus members with various other symbiotic and free-living lifestyles. The research projectssection of this site describes our ongoing efforts to describe the rates and patterns of genome-scale molecular evolution and relate these changes to organismal evolution. The software section provides access to the tools we’ve developed that may be useful for other researchers. The genomes and data section provides links to sequences, annotations and experimental data, plus information on ongoing genome projects involving GEL personnel and collaborators.