Death During Remission Stage of Pernicious Anemia.

Abstract

That pernicious anemia is a chronic disease characterized by striking spontaneous remissions and recidives has long been recognized. During such remissions it has been frequently observed that the blood picture may return to normal or approximately so; the hyperchromatic megalocytosis characteristic of the disease may disappear wholly. Since the introduction of the liver-treatment such periods of improvement occur much more frequently than in the past, during which the hematologic examination shows none of the blood changes characteristic of pernicious anemia. When a patient is examined during such a stage of remission the diagnosis of pernicious anemia by means of the