BACKGROUND
Previous work suggests that impairments in executive function and verbal memory in particular may persist in euthymic bipolar patients and serve as an indicator of genetic risk (endophenotype).
METHOD
A systematic review of the literature was undertaken. Effects sizes were extracted from selected papers and pooled using meta-analytical techniques.
RESULTS
In bipolar patients, large effect sizes (d>0.8) were noted for executive functions (working memory, executive control, fluency… CONTINUE READING