PyMS is a StarCraft modding suite writting using Python 1.5, meaning it will work for Mac users and Windows users alike (actually it will run on most OS's if it matters). PyMS contains 8 programs to edit various StarCraft files:

AI Scripts

GRP Files

All DAT Files

Palette Files

TBL Files

GOT Files

LO? Files

TRG Files

Currently the programs are all considered Beta, but should be stable. Each program includes a comprehensive command line interface, and only PyTRG doesn't have a GUI. More editors are planned like a Special Palette editor, IScript editor, Tileset editor, and font editor, but the current programs are a higher priority at the moment. Currently the documentation is lacking, currently only having help on the command line interface and installation, but it has good information on some of the programs. Most programs are straight forward and designed after other modding programs, so they should be easy to figure out and get used to.

Doubtful. It'll still be used. Consider StarCraft to be the "basic" game for modding, like WC2 was for StarCraft. Sure it's a difference between 2D and 3D, but StarCraft (1) will still be used in the future.