Machine learning has captured great attention in recent years due to its critical problem-solving capability. On the other hands, the 5G network with its great speed, flexibility, and sophisticated design, makes machine learning an attractive way to solve challenging research problems. In this special issue, we are calling for papers that study how machine learning can be used to solve challenging research problem in wireless networks. The special issue will accept a wide range of research problems in the wireless network. A list of the topics covered by the special issue (but not limited to) is as follows.