Preparation and Storage

This product is an active protein and may elicit a biological response in vivo, handle with caution.

Reconstitutionreconstitute in sterile 18MOhm/cm water at not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

General Info

Alternative names

Colony stimulating factor 1

Colony stimulating factor 1 (macrophage)

Colony stimulating factor macrophage specific

CSF 1

CSF-1

CSF1

CSF1_HUMAN

Csfm

Lanimostim

M CSF

M-CSF

Macrophage colony stimulating factor

Macrophage Colony Stimulating Factor 1

MCSF

MGC31930

Processed macrophage colony-stimulating factor 1

see all

FunctionGranulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy.

Post-translationalmodificationsGlycosylation and proteolytic cleavage yield different soluble forms. A high molecular weight soluble form is a proteoglycan containing chondroitin sulfate.Isoform 1 is N- and O-glycosylated. Isoform 3 is N-glycosylated.