A year has passed since House (Hugh Laurie) crashed his car into Cuddy’s (Lisa Edelstein) home, and we find House spending time behind bars at the East New Jersey Correctional Facility under the close watch of the prison warden (guest star Paré). When an antagonistic prison gang leader makes a serious threat, House solicits the help of a fellow inmate (guest star White), but when another inmate’s unusual medical symptoms spark his curiosity, House must come up with creative ways to treat the patient while navigating prison rules. House meets Dr. Jessica Adams (Odette Annable), a young, intelligent and bright-eyed clinic doctor, but when they are faced with a controversial opportunity to diagnose the patient’s life-threatening illness, Adams is confronted with a choice to trust House and put her career on the line or play by the book in the all-new "Twenty Vicodin" season premiere episode of HOUSE airing Monday, Oct. 3 (9:00-10:00 PM ET/PT) on FOX. (HOU-801).(TV-14 D, L, V)

Timeline

House fled the country for three months after driving his car into Cuddy's housse.. Now in prison for 8 months and up for a possible parole due to over-crowding.

Patient of the Week

A fellow prisoner has joint pain. House tells him to go to the clinic.

How House gets involved:

Contradicts the prison doctor's diagnosis.

The privacy invasion / ethical breach / Rule Breaking

House is in prison. Whatever ethics he had on the outside has long since been abandoned. He lies, cheats, steals, of course. And acts stupidly. Back on vicodin

Preliminary diagnoses:

House is sure it is Lupis. The prison doctor doesn't see the rash. House finds the rash but later finds it isn't Lupis. Then House thinks it is a tumor in the lung. Then a toxin. Then food allergy.

The final diagnosis

Mastocystosis

Who Came up with final diagnosis

House. Then it was the prison doctor who proved it.

Clinic Patients

None.

Additional Information:

He didn't bother with a lawyer when he was discovered back in the country. He took the first deal he was offered.

House gets interested in a case in prison so when he sees a prison doctor with what he knows is a wrong diagnosis, he tells her she is wrong and later when he tells her what to do, she asks "Why are you so sure I'm going to do as you say?"
"Because you're a smart, old money trust-fund girl who took this job because your liberal ideology makes you want to make a difference but you're already getting bored and this is intersting."
"Why would you say any of that?"
"Your shoes: a different, expensive pair every day. But never leather which means you are both rich and liberal. Antique locket: it's polished gold not some hipster thing. It's a family family heirloom which means family money. Olster scarf, only on Fridays which means you did your residency at Hopklins which means you're smarter than our interations would so far indicate. And your eyes---the only time you haven't looked bored in the three months you've been here is when we were discussing the diagnosis. So, yeah, you'll treat him for Lupis."

Dr. Adams insists on knowing what House is going to do when he gets out of prison since he says he is leaving medicine. "Before I went to med school, I thought about getting a Ph.D. in physics. You ever heard of dark matter? The way the galaxies rotate, the motion of the universe means there is six times more stuff than we can detect. But it's theorized, no one's ever proved it exists."
"So, uh. So you want to research it? Why?"
"Totally devoid of humanity."
"Me and humanity got together too young."
"It's the greatest mystery there is. The theory of everything."
"And completely divorced from humanity."
"Oh, me and humanity. We got together too young."