Weitere Antikörper gegen EID1 Interaktionspartner

SCF (zeige KITLG Antikörper)(FBXO21 (zeige FBXO21 Antikörper)) polyubiquitylates EID1 both in vitro and in vivo and is required for the efficient degradation of EID1 in both cycling and quiescent cells.

The results suggest that EID1 is a bona fide substrate of FBXO21 (zeige FBXO21 Antikörper) and that the control of EID1 abundance by SCF (zeige KITLG Antikörper)(FBXO)(21 (zeige FBXO21 Antikörper)) might affect the transcriptional repression activity of EID1.

Pcid2 (zeige PCID2 Antikörper) is present in the CBP/p300 (zeige CREBBP Antikörper)-EID1 complex to control the switch balance of mouse and human embryonic stem cells through modulation of EID1 degradation.

An unexpected EID1-binding site on SHP (zeige LAMC1 Antikörper) is located at the N terminus of the receptor, where EID1 mimics helix H1 of the nuclear receptor ligand-binding domain.

This study demonstrated that overexpression of EID1 reduced hippocampal long-term potentiation and impaired spatial learning and memory function in the transgenic mice

Pcid2 (zeige PCID2 Antikörper) is present in the CBP/p300 (zeige CREBBP Antikörper)-EID1 complex to control the switch balance of mouse and human embryonic stem cells through modulation of EID1 degradation.

This study supports Cri1 as the major locus controlling susceptibility following murine infection with C. rodentium, and suggests a cause of mortality common to the susceptible C3, C3Ou and FVB strains of mice.

EID-1 is expressed in the mouse testis, and its expression decreases during testis development. The results of the present study suggest that EID-1 can act as a repressor, regulating the function of SF-1 (zeige SF1 Antikörper).

EID1 Antigen-Profil

Protein Überblick

Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms (By similarity).