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A better understanding of the pathogenic pathways involved in lung disease in patients with RA should aid the development of specific therapies.

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Review Article 09 August Cutaneous lupus erythematosus encompasses a broad spectrum of skin lesions that can occur in isolation or as a manifestation of systemic lupus erythematosus. Insights into the cellular and molecular pathogenesis of cutaneous lupus erythematosus have triggered the development of new therapeutic strategies. Research Highlight 26 September In Brief 23 September Research Highlight 23 September Stanford University.

Conference Calendar Find out which meetings will be attended by the editors of Nature Reviews Rheumatology. Search Nature Reviews Rheumatology. Review Article 12 September The IL-1 family of cytokines and receptors in rheumatic diseases Cytokines from the IL-1 family perform important functions in innate immune reactions, but can also be involved in chronic inflammatory diseases.

Review Article 04 September Bedside to bench: defining the immunopathogenesis of psoriatic arthritis Data from clinical trials of novel targeted therapies for psoriatic arthritis and other autoimmune diseases, which have produced sometimes surprising results, can inform our understanding of the immunopathogenesis of these diseases and help to identify the most relevant therapeutic targets. Review Article 27 August Mechanisms of lung disease development in rheumatoid arthritis Rheumatoid arthritis RA -associated lung disease is difficult to treat and is associated with increased morbidity and mortality.

There are more than types of these diseases, including rheumatoid arthritis , osteoarthritis , gout , lupus , back pain, osteoporosis , and tendinitis.

Some of these are very serious diseases that can be difficult to diagnose and treat. They treat soft tissue problems related to musculoskeletal system sports related soft tissue disorders. Local diseases and lesions affecting the joints and structures around the joints including tendons, ligaments capsules, bursae , stress fractures , muscles, nerve entrapment , vascular lesions , and ganglia. For example:. Following are examples of methods of diagnosis able to be performed in a normal physical examination.

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Most rheumatic diseases are treated with analgesics , NSAIDs nonsteroidal anti-inflammatory drug , steroids in serious cases , DMARDs disease-modifying antirheumatic drugs , monoclonal antibodies , such as infliximab and adalimumab , the TNF inhibitor etanercept , and methotrexate for moderate to severe rheumatoid arthritis. Occupational therapy can help patients find alternative ways for common movements which would otherwise be restricted by their disease. Patients with rheumatoid arthritis often need a long term, coordinated and a multidisciplinary team approach towards management of individual patients.

Treatment is often tailored according to the individual needs of each patient which is also dependent on the response and the tolerability of medications. Rheumasurgery - sometimes called rheumatoid surgery - is a subfield of orthopedics occupied with the surgical treatment of patients with rheumatic diseases.

Rheumasurgical interventions can be divided in two groups. The one is early synovectomies , that is the removal of the inflamed synovia in order to prevent spreading and stop destruction. The other group is the so-called corrective intervention, i.

Recently, a large body of scientific research deals with the background of autoimmune disease , the cause of many rheumatic disorders. Also, the field of osteoimmunology has emerged to further examine the interactions between the immune system, joints and bones. Epidemiological studies and medication trials are also being conducted.

Comorbidity in Rheumatic Diseases

Scientific research on biologics and clinical trials on monoclonal antibody therapies have added a new dimension to the medical treatment of arthritic disorders. Rheumasurgery emerged in the cooperation of rheumatologists and orthopedic surgeons in Heinola , Finland, during the s. Hardcover ISBN: Imprint: Saunders.

Rheumatology – Health Sciences Library E-Book Database

Includes access to the fully searchable text online at expertconsult. Covers the treatment of pediatric patients as well as adults so that you can properly address the particular needs of any patient you see. Features the guidance and specific recommendations of experts from United States and Europe for a state-of-the-art approach to the variety of treatments currently in use.