Definition of Speckled iris

Speckled iris: Due to little
white (or lightly colored) spots that are slightly elevated
on the surface of the iris. These spots, arranged in a ring
concentric with the pupil, occur in normal children but are
far more frequent in Down's syndrome (trisomy 21). They
were described in 1924 by Thomas Brushfield, are called
Brushfield's spots, and are due to aggregation of a normal
iris element (connective tissue).