An animated sketch-comedy show, Sclopio Peepio comprises short, singular routines, short films, and songs. Each episode is a quarter-hour long, with some sketches lasting only a few seconds.As part of the main cast, Affion Crockett, Ilana Glazer, Darrell Hammond, Gabourey Sidibe, and Neely provide the voices of various characters. One guest star appears each episode.