Antagonist binds to receptor, forms a drug-receptor complex and eventually dissociates

Stops other things having effect on receptor

25

What are the 4 types of receptor?

1. Ion channel receptors

2. G protein coupled receptors

3. Enzyme linked receptors

4. Nuclear receptors

26

What are ion channels receptors? Examples?

Molecule binds to receptor, changes conformation and ions flow through

E.g.

Nifedipine - calcium channel blocker for hypertension

Nitrazepan - benzodiazopine GABA receptor modulator

27

What are G protein coupled receptors? Examples?

7 transmembrane domain receptor, can bind to agonist which leads to conformational change of receptor which leads to activation of G-protein within the cell, this activates target enzyme which creates a secondary messenger