Her smiling face greets everyone who enters the investigation room at Bransholme Police Station, where a team of detectives is hard at work.

It is a telling sign that Renata Antczak is at the forefront of everyone's minds as they work tirelessly to crack the mystery as to what has happened to the loving mum who has disappeared without a trace.

This is the operations centre of the Major Crime Team investigation into the disappearance of Renata, which for the past ten months has been treated as a murder inquiry.

MISSING: Renata Antczak

The 30-strong team is led by Detective Superintendent Tony Cockerill and has been in place for year. Although he is marking today's anniversary of her disappearance by shedding light on the investigation and renewing an appeal for information, the pace of the inquiry has never really slackened.

On the far wall are whiteboards filled with the writings of a black marker, names, photographs and other details of a constantly evolving picture as officers strive to answer the question that has faced them since day one - what happened to Renata after she dropped her 11-year-old daughter off at school that spring morning?

The effort to solve the case and provide answers for her family is huge. "It’s the biggest investigation in terms of lines of inquiry and size of reach in 20 years at least," said Det Supt Cockerill. "We are still driven and we are still pursuing all lines of inquiry we possibly can."

INVESTIGATION: Detective Superintendent Tony Cockerill talks to a member of the team working on the Renata Antczak case, which is being treated as a murder inquiry (Image: Richard Addison)

Alongside the more traditional methods of police work, the team has utilised the enormous reach of social media, with a targeted Facebook campaign carrying a multilingual YouTube video of Renata's case that has been seen by at least 300,000 people across the globe.

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It shows the mother-of-two in a variety of settings - at work, at home beside a Christmas tree, wrapped up against the cold, and frozen in time in a CCTV picture outside the school, in what has become one of the iconic images of the search. In all she is immaculately dressed and appears confident and happy.

After such intense work on the case, looking into her background and the circumstances of her life, the man leading the investigation has built up a detailed knowledge of the woman at the centre of it.

ON THE CASE: A detective at work (Image: Richard Addison)

Det Supt Cockerill said: "She trained as a lawyer in Poland and was a devoted mum. She liked to keep fit and was a member of a gym.

"Having never met her myself, because of the level of investigation we have carried out I almost feel like I know her, and it’s heart-breaking to think that she’s not been found, that her daughters have unanswered questions, and that she misses birthdays and Christmas, which I don’t believe she would do."

Renata was 49 when she disappeared and would since have turned 50. Det Supt Cockerill described the fact she has missed such personal milestones - with her youngest about to turn 12 - as "extremely significant". Her other daughter is 24.

In Det Supt Cockerill's office down the corridor is another whiteboard also featuring details of the investigation. These were removed before the Mail was allowed to photograph the senior officer at his desk.

Asked if he was able to switch off, he smiled and said: "You end up living and breathing it because it’s so immersive. The level of detail, not just for me but for the team, is exceptional because we need to understand what has happened."

MISSING: Renata Antczak

As well as the operations room there is another room on the ground floor dedicated to the inquiry, which focuses more on the clerical and administrative side of the work. Each new lead or line of inquiry potentially triggers others, and all are carefully logged, recorded and coordinated. It is a mammoth task.

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So far all attempts to find Renata "alive and well" - and they have been exhaustive - have proved "fruitless". But that does not in any way diminish the team's resolve to keep looking, to be in the position where they can finally provide answers to her family.

"I’m determined that we won’t leave any stone unturned to find out what happened to her," Det Supt Cockerill said.

Detective Superintendent Tony Cockerill (Image: Richard Addison)

The anniversary of the disappearance, an extremely difficult time for Renata's family, comes with a renewed appeal to the public to report any information that might help police find her. Det Supt Cockerill said: "We are continuing to support the family through what is a very difficult time.

"If there is someone out there who has information that might assist, I would just encourage them to contact us in good conscience, or use the Crimestoppers reward system."

Anyone providing Crimestoppers with information leading to a conviction could claim a reward of up to £10,000.

Gemma Gibbs, Crimestoppers Regional Manager for Humberside, said: "Renata was a popular woman and was in close contact with friends and family in both England and her native Poland, so for that dialogue to be completely cut off raises lots of questions.

LAST SEEN: Renata Antczak dropping her daughter off at Broadacre Primary School

"Her two daughters deserve to know what has happened to their mother. They are likely to be going through a very difficult time at the moment, so I am asking anyone with information on Renata’s potential murder to contact our charity.

"We won’t judge you, we’ll just listen to what you know and pass it on. You will always remain 100 per cent anonymous. Always."

Anyone with information can call the incident room on (01482) 220427, or Crimestoppers on 0800 555 111.