Chromium-51 is the most commonly used readioactive marker for the labeling of target cells in cytotoxicity assays. The common name for such assays Chromium Release also describes the fundamental method behind the assay procedure. Methods for the precise and accurate quantification of cytotoxicity are of fundamental importance in immunology particularly for the study of tumor and virus cytolysis.Cytotoxicity assays can be used in order to study either the defense mechanism in a specific patient or to study target cells, depending on whether the effector (or killer) cells are the unknowns. It can also be used for the study of certain drugs on the immune system.Chromium fulfills the requirement of a good label. It is generally non-toxic (as Na2CrO4), it is easily taken up by the cells, it is spontaneously released only in relatively small amounts, its detection is easy and sensitive and it does not change the morphology and characteristics of the target cell.

Specifications

Concentration

1 mCi/mL

Detection Method

Radiometric

Fresh Lot Days

Every other Friday

Half Life

27.71 days

Label Position

Specifically Labeled

Radioisotope

Cr-51

Radionuclide

51Cr

Shipping Condition

Ambient

Special Ordering Information

This is a radioactive product - shipping address must have a license to receive radioactive materials.

Brochure

For over 50 years PerkinElmer has been a leading supplier of radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments. Today is no different. We have always been committed to providing you products for all of your radiometric needs and we are still committed today.

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Guide

This document contains general information designed to provide a basic understanding of radiation safety. While we believe the information to be accurate, regulatory requirements may change and information contained herein is not tailored to individual needs.

This document contains general information designed to provide a basic understanding of radiation safety. While we believe the information to be accurate, regulatory requirements may change and information contained herein is not tailored to individual needs.