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Stephen admits he didn’t always get along with his older sister but he is missing her badly.

He said: “She was a pain in the backside, but she was our pain in the backside.”

Patti’s friends and family have not heard from her since Monday, November 13, 2017, three weeks after her flitting to Girvan.

Her worried family reported her missing on March 14, 2018 and it’s understood she hasn’t used her bank card or phone.

Detectives, who admit “she may have come to harm”, probed the possibility she had gone to Spain where she lived previously, but passport checks revealed she has not left the country.

Cops spent months searching a property in Burnfoot Crescent, Glenburn and the flat she moved to in Girvan but found no trace.

Police used specialist kit at the Burnfoot Avenue property

Forensic officers sealed off the property and were seen digging with shovels in the back garden.

Stephen, 44, added: “We know the police are trying their best. We know they are trying everything but they have nothing to go on.

“It has been really quiet from the police.”

Stephen Henry, 44, brother of missing Paisley woman Patti Henry

It was also revealed last week that Interpol had issued a yellow notice, usually used for victims of abduction and unexplained disappearances.

Patti is described as white, 5ft 10ins, of slim build and has collar-length brown hair.

She has a tattoo of two clouds and a rose bearing the name Patti on her left upper arm and a tattoo of a dolphin on her hip.

Police Scotland confirmed enquiries are ongoing.

A spokeswoman said:”Despite extensive police enquiries and numerous media appeals, we have been unable to locate Patricia.

“One year on, officers remain dedicated to this missing person investigation and we would welcome any information from the public, no matter how insignificant it may seem.

“If anyone has information on the whereabouts of Patricia Henry that could assist our investigation, we would urge them to contact Police Scotland through the incident room on 01563 505172 quoting reference number 3401 of March 14, 2018."