Structure of human purine nucleoside phosphorylase H257F mutant

The structure was published by Murkin, A.S., Birck, M.R., Rinaldo-Matthis, A., et al., Taylor, E.A., Almo, S.C., and Schramm, V.L., in 2007 in a paper entitled "Neighboring group participation in the transition state of human purine nucleoside phosphorylase." (abstract).

This crystal structure
was determined using
X-ray diffraction
at a resolution of 2.28 Å and deposited in 2005.

The PDB entry contains the structure of Purine nucleoside phosphorylase.
This molecule has the UniProt identifier P00491 (PNPH_HUMAN). The sample contained 289 residues which is 100% of the natural sequence. Out of 289 residues 282 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):