Acellular matrix as a substrate for tissue-engineered graft of heart valve

AbstractIn many cases heart valve prosthetics is the only solution to save patient’s life. All mechanical prosthetics currently used are not able to perform function in the body fully because non-living materials are used for their production. Tissue engineering provides the reconstruction of viable valves using stem cells. Acellularized three-dimensional tissue scaffolds as a matrix for autologous cells do improve function of heart valves and promote heart regeneration.