Duke at Georgia Tech (ACC Network, 12:20 p.m. ET)
The Blue Devils hit the road for Atlanta looking to slow down the Yellow Jackets' rushing attack. Georgia Tech has rolled up 64.5 points per game over the past two outings against Bowling Green and Louisville, running the ball at will. The Blue Devils head to Atlanta with a 4-0 ATS mark over their past four road games and 6-2 ATS in the past eight overall. However, they're just 2-5-1 ATS in the past eight ACC battles and 0-3-1 ATS in their past four games in the month of October. The Ramblin' Wreck is 8-3 ATS in the past 11 at home, but just 2-6 ATS in their past eight overall and 1-4-1 ATS in their past six tries against winning teams. In this series, Duke, the underdog in each of the past four meetings, is 4-0 ATS with the under going 4-1 ATS in the past five battles in Atlanta.

Louisville at Boston College (ACC Network, 12:30 p.m. ET)
Louisville has opened the conference slate with three straight setbacks and they're heavily favored to suffer a fourth loss in Chestnut Hill on Saturday. The Cardinals hit the road with an 8-20-1 ATS mark ove rtheir ;ast 29 games, 1-4 ATS in the past five road games and a dismal 2-10 ATS mark across their past 12 contests against winning teams. The Eagles hve posted a 9-1-1 ATS record in the past 11 conference games, while going 12-3-1 ATS in the past 16 overall. BC is also 5-2-1 ATS in the past eight home games, 10-3-1 ATS in the past 14 home outings against a team with a losing road mark and 5-1 ATS in the past six against losing squads. However, the road team is 4-0 ATS in the past four meetings in this series.

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Pittsburgh at Notre Dame (NBC, 2:30 p.m. ET)
The Panthers head into South Bend in a rivalry game, although Vegas isn't expecting much resistance from Pittsburgh. Playoff-hopeful Notre Dame is installed as a three-touchdown favorite heading into Saturday afternoon. Pitt has posted a 5-2 ATS mark in their past seven against teams with a winning record, but they're 6-19-1 ATS in the past 26 non-conference battles. Notre Dame is 5-2 ATS in the past seven games overall and 5-2 ATS in their past seven against the ACC. The under has been popular for both sides lately, going 7-1 in Pitt's past eight road games, and 6-2 in their past eight against independents. The under is also 13-5-1 in the past 19 overall. The under is also 4-1 in Notre Dame's past five home games and 7-3 in their past 10 overall. In this series, the Panthers are 3-0-1 ATS in the past four meetings in South Bend, while the underdog is 8-1-1 ATS in the past 10 in this series. The road team is also 7-2-1 ATS in the past 10 meetings.

Miami-Florida at Virginia (ESPN2, 7:00 p.m.)
Miami arrives with a lot of confidence after erasing a 27-7 deficit at home last week against Florida State to pick up a one-point win against their rivals. Now, will there be any kind of hangover? The Hurricanes have held steady as a favorite in the neighborhood of 6 to 6 1/2 points this week. However, Miami is just 3-7 ATS in their past 10 overall, 1-4 ATS in their past five ACC games and 1-4 ATS in the past five road games while going 1-5 ATS in the past six against winning teams. Conversely, UVA is 4-1 ATS in their past five home games while going 8-3 ATS in the past 11 against winning teams. They're also rested, and they're 9-2 ATS in their past 11 coming off a bye week. The underdog is 12-2 ATS in the past 14 meetings in this series, while the road team is 6-1 ATS in the past seven in this series. Miami has cashed in just one of the past five in this series.

Virginia Tech at North Carolina (ESPNU, 7:00 p.m.)
The Hokies will be angry after failing a huge national test last week at home against Notre Dame. Now, they look to take out their anger on the Tar Heels in Chapel Hill, a team which has won just once in four tries overall this season. Virginia Tech is 2-9 ATS in the past 11 road games against teams with a losing home record, while UNC is 21-7 ATS in the past 28 at home against teams with a winning road record. The Tar Heels are an impressive 4-1 ATS in the past five ACC games, too, while going 5-2-1 ATS in the past eight overall. Va. Tech has dominated this series in the recent past, at least against the number, going 5-0 ATS in the past five and 5-1 ATS in the past six trips to Kenan Stadium. The 'under' is 9-2 in the past 11 meetings in this series, while going 4-1 in the past five in Chapel Hill.

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