Zoloft is taken orally, once a day. Admission is not dependent on food, but when the pill taken during meals, is able to act faster. The initial dosage for obsessive-compulsive neurosis and depression is minimal, not more than a tablet. In case of panic disorder and social phobia, the dosage should be half that. Increase in dosage is carried out a week after the start of taking with normal tolerability of the drug.