Spider-Man obviously can't tank a nuke. I don't think he could tank a point blank grenade either on average. The Punisher rocked him pretty hard with a grenade a few years ago, and was able to steal one of his web-shooters and escape because of it.

As far as pumpkin bombs go, Ben Reilly once shielded Flash Thompson from a pumpkin bomb blast with his body, and had to bandage his torso immediately afterwards, but he wasn't put down by it.

There's another instance which comes to mind where Macendale Hobgoblin tossed a pumpkin bomb at Peter while he was floating in water, and somewhat groggy due to having been gassed not long before that, and it was implied that the bomb would've killed him, had Moon Knight not detonated it prior to impact with one of his throwing weapons.

Come to think of it, there's another instance from the Silver Age where it was explicitly stated that a direct hit from a pumpkin bomb would've been fatal to Peter, and although he was able to avoid a direct hit by parrying the incoming bomb with his webbing, he was still knocked unconscious by it going off near him.

Spider-Man obviously can't tank a nuke. I don't think he could tank a point blank grenade either on average. The Punisher rocked him pretty hard with a grenade a few years ago, and was able to steal one of his web-shooters and escape because of it.

As far as pumpkin bombs go, Ben Reilly once shielded Flash Thompson from a pumpkin bomb blast with his body, and had to bandage his torso immediately afterwards, but he wasn't put down by it.

There's another instance which comes to mind where Macendale Hobgoblin tossed a pumpkin bomb at Peter while he was floating in water, and somewhat groggy due to having been gassed not long before that, and it was implied that the bomb would've killed him, had Moon Knight not detonated it prior to impact with one of his throwing weapons.

Come to think of it, there's another instance from the Silver Age where it was explicitly stated that a direct hit from a pumpkin bomb would've been fatal to Peter, and although he was able to avoid a direct hit by parrying the incoming bomb with his webbing, he was still knocked unconscious by it going off near him.

you should brush on some spidey comics, Spider-Man cantank a point blank grenade explosion

this is a warhead missle that still clearly hits peter

fully conscious with again, minimal damage

An actual grenade level explosion, hitting peter

Zero damage, except for a torn suit

^Scan blatantly explains that the doombot explosion is equal to that of a m67 grenade BTW

I recall one where Electro blew up a portion of building top with Peter in it and it didn't even knock Pete down.

And he was unconscious for two days after that. Maybe you have a different notion of what it means to 'tank' something than I do, because merely surviving something isn't the same as tanking it in my book. Tanking something suggests to me that you were able to stand up to that thing, like a human tank.

^Scan blatantly explains that the doombot explosion is equal to that of a m67 grenade BTW

Yeah, but he appears to be dodging the explosion in that panel (it goes off somewhere behind or beside him, not on him). He doesn't dodge the one on the following page, but that wasn't point blank, as the Doombot exploded on Colossernaut's fist, and Spidey was some distance away from him.