Special Instructions

Method Name

Fluorometric

Reporting Name

Alpha-Galactosidase, Leukocytes

Specimen Type

Whole Blood ACD

Specimen Required

Specimen must arrive within 72 hours of draw to be
stabilized. Specimen received after 72 hours could have falsely
normal results. Draw specimen Monday through Thursday only and not
the day before a holiday. Specimen should be drawn and packaged
as close to shipping time as possible.

Container/Tube:

Preferred: Yellow top
(ACD solution B)

Acceptable: Yellow
top (ACD solution A)

Specimen Volume: 6 mL

Collection Instructions: Do not transfer blood to other
containers.

Forms:

1. New York
Clients-Informed consent is required. Please document on the
request form or electronic order that a copy is on file. An
Informed Consent for Genetic Testing (T576) is available in Special
Instructions.

Carrier females usually have alpha-galactosidase levels in the
normal range; therefore, molecular sequence analysis of the
GLA gene (FABRZ / Fabry
Disease, Full Gene Analysis) is recommended as the appropriate
diagnostic test for females.

Day(s) and Time(s) Performed

Specimens are processed Monday through Sunday.

Assay is performed on Tuesday.

Analytic Time

8 days

Specimen Retention Time

WBC homogenate stored 1 month

Test Classification

This test was developed and its performance characteristics
determined by Mayo Clinic in a manner consistent with CLIA
requirements. This test has not been cleared or approved by the
U.S. Food and Drug Administration.