Dan from UneasySilence works between Windows and Mac OS a lot, and like most multi-environment users, he shares foldersbetween his Mac and PC. However, he's not a big fan of the litter of thumbs.db his Windows computer leaves behind for his Mac, nor does he care for the .DS_Store file his Macs leave for Windows.

So you've made the switch to Mac, but kept your old PC, and now you've got both connected …
Read more Read more

On your Windows PC, just turn off thumbnail caching to get rid of thumbs, and on your Mac, you can run a terminal command that disables .DS_Store files over a network. This should help get rid of the clutter from your shared folders.