Adenosine triphosphoric acid pool in rat tissues after the administration of beta-mercaptoethylamine

Abstract: Pool of ATP in thymus, spleen and liver tissues of non-irradiated rats underwent distinct tissue-specific alterations just after intraperitoneal administration of hydrotartrate of beta-mercaptoethylamine (cisteamine, MEA) at e radioprotective dose 300 mg/kg. The data obtained suggest that there are marked impairments in turnover of adenylic nucleotides at the period corresponding to manifestation of the MEA radioprotective efficiency.