서민호서성일백원기이상숙김재룡Min-Ho SuhSeong-Il SuhWon-Ki BaekSang-Sook LeeJae-Ryong Kim2018-01-30T07:39:32Z2018-01-30T07:39:32Z1992대한미생물학회 The Korean Society For Microblology, Vol.27(1) : 87-92, 19920253-3162oak-bbb-961http://kumel.medlib.dsmc.or.kr/handle/2015.oak/23349A total of 149 HBs Ag positive and 15 normal serum samples were tested for the detection of Hepatitis B virus (HBV) DNA to evaluate the relationship between serum HBV DNA positivity by DNA blot hybridization and serological markers positivity. by ELISA.
Twenty-seven (79.4%) of 34 patients positive for both HBs Ag and HBe Ag were positive for HBV DNA compared with 33(28.7%) of 115 HBs Ag positive but HBe Ag negative individuals.
In addition, among all patients positive for HBV DNA, there was a statistically significant correlation between the concentration of HBV DNA in serum and the presence or absence of HBe Ag.
None of the 15 HBs Ag and HBe Ag negative individuals tested was positive for HBV DNA. But the detection rate of HBV DNA in the cases of HBe Ag negative was as high as 28.7%(33/115), so we concluded that detection of both HBe Ag and HBV DNA should be necessary in order to evaluate the infectivity of the HBs Ag positive sera.restrictionSchool of MedicineBY_NC_NDhttp://creativecommons.org/licenses/by-nc-nd/2.0/krHepatitis B virusDot blot hybridizationInfectivity혈청내 B형간염 바이러스 DNA의 Dot Blot Hybridization에 의한 검출Detection of Hepatitis B Virus DNA in Serum by Dot Blot HybridizationArticle서민호서성일백원기이상숙김재룡Suh, Min HoSuh, Seong IlBaek, Won KiLee, Sang SookKim, Jae RyongDept. of Microbiology (미생물학)Dept. of Pathology (병리학)Dept. of Laboratory Medicine (진단검사의학)27187대한미생물학회 The Korean Society For Microblology92