NAPA, Calif. — A day after an earthquake caused at least $1 billion in damage to about 150 homes and businesses in California’s wine capital, workers Monday were cleaning up the debris, mopping up thousands of dollars in high-end vintages, and struggling to reopen in advance of the summer’s last holiday weekend.

With the dust still settling from Sunday’s magnitude-6.0 temblor near the city of Napa, government and tourism officials said most of the region was safe and encouraged visitors to keep flocking to the charming towns, tasting rooms, restaurants, and spas that drive the Napa Valley economy.

While cleanup and rebuilding will take time and broken water mains remained a problem, they said, the worst damage and disruption was confined to the city’s downtown, where a post office, a library, and a 141-room hotel were among the buildings deemed unsafe to occupy.

The strongest earthquake to hit the San Francisco Bay Area in a quarter-century injured about 200 people, fractured roads, started fires that destroyed or damaged several homes, ruptured about 60 gas lines, and cut power to thousands.

Pacific Gas & Electric said Monday that all the gas leaks had been stopped. About 150 customers were without electricity, down from a total of 70,000 after the quake.

Napa city officials said Monday that 33 of the damaged buildings were uninhabitable. In Napa Valley, two hotels and 12 wineries were closed, as well as many of the businesses downtown. Local officials gave a preliminary estimate of $1 billion in property damage in Napa Valley but said they hope the long-term economic impact of the quake to businesses will be modest. Bill Dodd, Napa County supervisor, said 80 percent of the valley’s 500 or so wineries were unaffected.

If people ‘‘think Napa is devastated, it’s anything but devastated. We’re only 24 hours out from an earthquake, and we’re on our way back,’’ Dodd said.