Serous cystadenomas (ie, microcystic adenomas) are benign neoplastic lesions that commonly occur in the sixth and seventh decades of life and tend to occur more often in female than in male patients. Morphologically, these lesions typically appear as a cluster of small cysts with a characteristic central scar. They can arise in any region of the pancreas and are often asymptomatic, but they also can cause symptoms in a minority of patients because of mass effect.