Introduction
Iron homeostasis is one of the main functions of the liver, being the main place for its storage. The liver controls the iron flow into and around the body via the synthesis of major proteins for iron metabolism such as transferrin and the production of the peptide hepcidin. [ 1 ] Hepcidin, a 25-amino acid peptide present in human serum and urine, is considered the main regulator of iron metabolism through binding to iron carriers, resulting in internalization and lysosomal degradation. [ 2 , 3 ] Inflammation, endoplasmic stress, and iron