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ZytoLight ®SPEC TP53/ATM Dual Color Probe

The ZytoLight SPEC TP53/ATM Dual Color Probe is designed for the detection of deletions affecting the genes TP53 and ATM. Chronic lymphocytic leukemia is the most common form of leukemia in Western population. TP53 gene deletions have been detected in patients with CLL, multiple myeloma, and acute myeloid leukemia. In CLL patients, allelic loss of the short arm of chromosome 17 is associated with treatment failure with alkylating agents and short survival times.

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