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Open Targets Workshop

28 March 2019

EMBL-EBI

Open Targets Workshophttps://www.ebi.ac.uk/training/events/2019/introduction-rna-seq-and-functional-interpretationhttps://tess.elixir-europe.org/events/open-targets-workshop-55d54e1b-0a19-4e14-9719-6df0ad7054b9In this workshop, we introduce Open Targets and its underlying projects for data integration for access and visualisation of biological data in drug target identification and discovery.2019-03-28 09:00:00 UTC2019-03-28 00:00:00 UTCEMBL-EBI, EMBL-EBIEMBL-EBIEMBL-EBI[][][]workshops_and_courses[]Open Targets

Regulatory Oxylipins

1 - 4 April 2019

Gent, Belgium

Regulatory Oxylipinshttps://vibconferences.be/event/regulatory-oxylipinshttps://tess.elixir-europe.org/events/regulatory-oxylipins-661da9dc-2159-4a34-8809-7851dfbe0b8aOxylipins, from plants and other organisms, form a constantly growing group of signalling molecules that comprise oxygenated fatty acids and their metabolites. The most renowned regulatory oxylipins are undoubtedly the jasmonates, which, following their discovery in the 1960s, became recognized as regulators of defence, floral organ development and fertility, as growth inhibitors and modulators of senescence, and as elicitors of specialized metabolism in numerous plant species. As such, the jasmonates currently belong to an elite group of heavily investigated phytohormones.
Over the last decade, the understanding of biosynthesis, metabolism, and action of regulatory oxylipins has greatly advanced. The ROXY2019 meeting wishes to bring together the international community and leading researchers in the field. Thereby it aims to provide a timely and exciting forum to present and discuss the recent advances and expertise on the study of these molecules that are so crucial for plant growth, development, metabolism, and interaction with the environment.
There will be seven plenary sessions that, through combining lectures from invited speakers and short talks on selected abstracts and posters, will highlight the various aspects involved in Regulatory Oxylipin research. These sessions cover the following major themes: Regulatory oxylipins in emerging model systems and non-plant systems, Biochemistry and structural biology, Control of growth and defence, Control of Metabolism, Reproduction, Jasmonate signalling mechanisms and Long-distance signalling, Ecology.
We look forward to your contributions to make this an exciting conference. See you in Gent!
The organizers
Alain Goossens and Ted Farmer
Poster information
Format: A0 (841 x 1189 mm / 33.1 x 46.8 in), portrait orientation2019-04-01 09:00:00 UTC2019-04-04 17:00:00 UTCVIB Conferences - Alain Goossens & Ted FarmerGhent University - Aula, 9, Voldersstraat, Gent, BelgiumGhent University - Aula, 9, VoldersstraatGentOost-VlaanderenBelgium9000[]conferences@vib.beFaculty of ScienceJournal of Experimental BotanyPCP (Plant & Cell Physiology)The Plant CellThe Plant Journal[][][]Regulatory OxylipinsBiochemistrystructural biologyMetabolismreproductionJasmonate signallingEcology

Open Targets Genetics at ESHG

15 June 2019

Sweden

Open Targets Genetics at ESHGhttps://2019.eshg.org/index.php/programme/saturday/https://tess.elixir-europe.org/events/workshop-at-eshgIn this workshop, we will introduce Open Targets Genetics Portal as part of the Open Targets ecosystem, highlighting variant-centric statistical evidence for prioritizing candidate causal variants at trait-associated loci, and identifying potential drug targets. We will present POSTGAP, a pipeline which merges genetic associations curated from literature with functional genomics, epigenetic and expression data (e.g., eQTL, promoter capture Hi-C, DNase hypersensitivity sites, regulatory elements) to resolve association signals at a locus and link each variant to its target gene(s) using a single evidence score. The portal also incorporates pre-computed fine-mapping at trait-associated loci across hundreds of UK Biobank phenotypes as well as cross-trait colocalization, furthering drug repurposing opportunities. This workshop will enable you to effectively use Open Targets Genetics to gain biological insight, prioritize genes, and inform target decision-making. Intended Audience: Attendees interested in the translational application of genetics and genomics with an emphasis on the identification of target genes of trait-associated loci, drug target identification, prioritisation and repurposing. Participants should bring their laptops for exploration of the Open Targets Genetics Portal in situ.2019-06-15 09:00:00 UTC2019-06-15 00:00:00 UTCGothenburg, SwedenGothenburgSweden[][][]workshops_and_courses[]Open Targets

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