International Workshop on CLL Clinical Staging

No anemia or thrombocytopenia, > or = 3 areas of lymphadenopathy (Rai Stage I - II)

Clinical stage C

Anemia and/or thrombocytopenia (Rai Stage III - IV)

There are no staging systems for other blood diseases. The acute leukemias and myelodysplastic syndromes are described and classified histologically by the French-American-British (FAB) classification.

An International Prognostic Scoring System has been developed for MDS, based on the bone marrow blast percentage, number of peripheral blood cytopenias, and cytogenetic subgroup, which stratifies cases into four risk groups. In addition, other prognostic classification systems for MDS include the FAB system (described above), the Bournemouth score, the Sanz score, and the Lille score.