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Doomsday + Mind's Desire + Beacon of Destruction is a quick win-the-game combo. You wouldn't want to be casting Doomsday unless its text basically says "win the game"... if you set it up right, though, it DOES.

While this smells nice, you also need an impressive nine mana for it to work, five of them colored! Moreover, doomsday puts five cards in your library, and since you can have at most 3 beacons, it's quite risky.
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LohorisNov 21 '10 at 0:23

2

@Lo'oris - I believe the five cards you choose are something like Ancestral Recall, Dark Ritual, Black Lotus, Mind's Desire, Beacon of Destruction. Pay U to Ancestral into Ritual and Lotus, then it basically costs you 1 more mana to cast Beacon of Destruction at least 4 times with Mind's Desire... I think that's roughly how it works.
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thesunneversetsNov 21 '10 at 3:16

oh, I didn't notice you arrange those cards as you wish... I assumed you shuffled them. (I also meant 4 beacons of course, not 3). Well, then it's a nice combo, with just the (huge) problem that it's a "win or die" and very vulnerable.
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LohorisNov 21 '10 at 10:41

Note that Mind's Desire is not legacy legal, and for Vintage is far from optimal due to the mana cost.
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Michel DaviotApr 19 '11 at 21:23

The problem with any strategy that begins with "get Laboratory Maniac" on the field is that you have to keep him on the field as you're drawing your last card. I guess there's Chromatic Sphere (card draw as a mana ability) to help with that, but it's still rather fragile.
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Alex PFeb 15 '12 at 20:32

@alex p i guess he did say successfully. I was thinking fun.
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DForck42Feb 15 '12 at 20:50