Donald Trump has promised to rip up the Iran deal on day one of his presidency and said that it's "one of the worst deals I've ever seen negotiated" in "[my] entire life."

Trump discussed of the Iran deal in his speech at the Republican National Convention in Cleveland, Ohio:

"Iran, the world's largest state sponsor of terrorism, is now flush with $150 billion in cash released by the United States — plus another $400 million in ransom. Worst of all, the nuclear deal puts Iran, the number one state sponsor of radical Islamic terrorism, on a path to nuclear weapons

"In short, the Obama-Clinton foreign policy has unleashed ISIS, destabilized the Middle East, and put the nation of Iran — which chants 'death to America' — in a dominant position of regional power and, in fact, aspiring to be a dominant world power."

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Syria, Iraq, and ISIS

After the invasion of Iraq in 2003 that deposed Saddam Hussein, the US has maintained a constant presence in the country as it struggles to establish new, credible leadership.

Meanwhile, Syria descended into chaos after its president, Bashar Assad, violently suppressed pro-democracy demonstrators in 2011. In both nations, the Islamic State has risen as a powerful and brutal military force in direct opposition to the West. In 2014, the US intervened in the conflict by offering funding, training, and airstrikes to support moderate opposition to Assad's regime.

In the same year, ISIS, an offshoot of Al Qaeda in Iraq, filled the power vacuum in the desert along the borders of the two adjacent, troubled nations. By almost all measures, ISIS has lost ground militarily since its peak. But it has continued to carry out or inspire attacks overseas.

"They will have 30 days to submit to the Oval Office a plan for soundly and quickly defeating ISIS. We have no choice. Any nation who shares in this goal will be our friend in this mission," Trump said.

He has also repeatedly criticized Clinton and Obama for refusing to use the words "radical Islamic terror."

NATO and Russia

Russian Prime Minister Vladimir Putin, right, talks to Government Chief of Staff Vyacheslav Volodin during a meeting on the development of local self-government in Pskov's Kremlin, some 404 miles northwest of Moscow, May 23, 2011. Thomson Reuters

Founded in 1949 by democratic nations in Europe and North America to defend against the spread of communism, the North Atlantic Treaty Organization (NATO) is the most powerful military alliance the world has ever known.

Though the Soviet Union has collapsed, Russia, under President Vladimir Putin's rule, has risen again to become a world power and a military threat.

Furthermore, Russia supports Syria's Bashar Assad, while the US supports opposition forces. In Syria, Eastern Europe, and even the Pacific, Russia promotes causes contrary to the interests of the US and the democratic West.

Trump departs from orthodoxy in US politics in that he embraces the totalitarian leader Putin. Donald Trump has criticized the NATO alliance as "obsolete," and welcomed praise from Putin.

When pressed to distance himself from Putin at NBC's Commander-in-Chief Forum earlier in September, Trump suggested that Putin is a better leader than Obama.

"He is very much of a leader. The man has very strong control over his country ... You can say, 'oh, isn't that a terrible thing,' I mean, the man has very strong control over his country," Trump said. "Now it's a very different system, and I don't happen to like the system, but certainly in that system he's been a leader, far more than our president has been a leader."

Peace between Israel and Palestinians remains one of the most elusive and sought-after solutions on the world stage.

Trump has questioned the US's military alliances generally but claims to remain resolute in supporting Israel. As he fancies himself a world-class negotiator and deal maker, he's expressed genuine interest in trying to establish himself as neutral between Palestine and Israel and eventually striking a deal for peace between them.

North Korea

North Korean leader Kim Jong Un inspects a flight drill of fighter pilots from the Korean People's Army's (KPA) Air and Anti-Air Force, in this undated photo released by North Korea's Korean Central News Agency (KCNA) on February 21, 2016. Reuters

Perhaps no regime on earth is as openly antagonistic toward the US as North Korea. Only China has any modicum of influence over the Hermit Kingdom.

Trump has repeatedly questioned the wisdom of the US's alliance with South Korea, where more than 25,000 troops are stationed. He has also suggested that the US should pull away from Japan, musing about the country developing its own nuclear weapons to defend itself.

Trump hopes his proposed hardline trade stance toward China would convince the country to intervene in North Korea.

"China has … total control over North Korea," Trump told "Fox & Friends" in January. "And China should solve that problem. And if they don't solve the problem, we should make trade very difficult for China."