This book offers concepts, methods and a framework to analyze healthcare data in new ways to improve patient health outcomes, improve population health and reduce costs. The framework takes the reader step-by-step through data warehouse and data management architectures, analytics algorithms and modeling techniques for applications in predictive medicine, optimization, machine learning, natural language processing, classification and data clustering. This book introduces the reader to data science for healthcare. It provides a clinical perspective to data including sources of open healthcare data, clinical prediction rules and much more.This book offers concepts, methods and a framework to analyze healthcare data in new ways to improve patient health outcomes, improve population health and reduce costs.