The theme of our laboratory is to study molecular mechanisms of how to interfere with bacteria, with the overarching aim to develop novel antimicrobial reagents to target bacterial infections. We work on essential bacterial processes and those nonessential for survival, with the latter having less selection pressure to develop resistance. To this end, we collaborate with microbiologists, chemical biologists, and biophysicists. Together, we employ a wide range of experimental approaches, including microbiology, genetics, chemical biology, molecular biology, combinatorial biology, biochemistry, biophysics, structural biology, and particularly protein crystallography.

Contact us:

Laboratory:

Location: Simon Hall MSB1 room 301

Phone: (812) 856-0239

Fax (Simon Hall): (812) 856-5710

Dr. Chen's Office:

Location: Simon Hall MSB1 room 305B

Phone: (812) 855-0491

E-mail: linchen@indiana.edu

We are constantly looking for highly motivated graduate and undergraduate students who are interested in biomedical research. If you are one of them, contact Dr. Chen at linchen@indiana.edu . Please include your resume and class schedule.