Summary

Prospective, observational pilot study of ten post-transplant patients presenting with
diarrhea while taking Mycophenolate Mofetil (MMF). These patients will undergo a standard
workup to confirm MMF induced diarrhea. A stool fecal calprotectin will be measured to
determine if it may be helpful in confirming the diagnosis of MMF associated diarrhea. Once
the diagnosis is confirmed, the patients will then be treated with a short course of
subcutaneous Octreotide which has been shown to cure this type of diarrhea.

We developed a long-acting drug-delivery system that supports subcutaneous administration of the peptidic somatostatin agonist octreotide - a blockbuster drug used to treat acromegaly and neuroendocri...

Runner's diarrhea is an acute exercise-induced diarrhea. Usually, this is not a pathological situation but it can affect performance. This review focuses on the discussion of the main causes of runner...

There have been very few prospective studies of first-line chemotherapy on advanced gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC). This phase II study assessed the activity and safety of i...

Medical and Biotech [MESH] Definitions

Rotavirus Infections

Infection with any of the rotaviruses. Specific infections include human infantile diarrhea, neonatal calf diarrhea, and epidemic diarrhea of infant mice.

Acetylesterase

An enzyme that catalyzes the conversion of acetate esters and water to alcohols and acetate. EC 3.1.1.6.

Megestrol Acetate

Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. It also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia. (From Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)

Melengestrol Acetate

A 6-methyl PROGESTERONE acetate with reported glucocorticoid activity and effect on ESTRUS.

Acetate-coa Ligase

An enzyme that catalyzes the formation of CoA derivatives from ATP, acetate, and CoA to form AMP, pyrophosphate, and acetyl CoA. It acts also on propionates and acrylates. EC 6.2.1.1.

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Relevant Topic

TransplantationOrgan transplantation is the moving of an organ from one body to another or from a donor site to another location on the patient's own body, for the purpose of replacing the recipient's damaged or absent organ. The emerging field of regenerative ...