Mark Sanford, a vocal critic of Donald Trump, lost his South Carolina congressional seat after the president injected himself into the bitter Republican primary

Rep. Mark Sanford, a vocal critic of President Donald Trump, lost his South Carolina congressional seat Tuesday hours after the president injected himself into the bitter Republican primary by stoking memories of the incumbent’s public extramarital affair seven years ago.

In the most dramatic result in primaries across five states, Sanford was the second incumbent House Republican to lose a primary this year — the latest victim of intense divisions among the GOP in the Trump era. Though he has a generally conservative voting record, his criticism of Trump as unworthy and culturally intolerant made him a target of the president’s most dedicated supporters, who often elevate loyalty over policy.

“He’s MIA and nothing but trouble,” Trump continued. “He is better off in Argentina.”

The swipe was a reference to Sanford’s unexplained disappearance from the state in 2009, which he later said was part of an affair he was carrying on with a woman in Argentina.

Even for a political figure with no shortage of confidence wading into his own party’s decision-making, Trump’s attack on Sanford was a bold case of going after a sitting member of Congress. It’s almost certain to make other Republicans even more reluctant to take him on, even as Trump has stirs division on trade, foreign policy and the Russia investigation.

Sanford had never lost a political race in South Carolina and his defeat Tuesday was an abrupt end to a roller-coaster political career that included a resignation as South Carolina’s governor following his admission of the affair.

After declaring victory Tuesday, Arrington asked Republicans to come together. And she reminded them who she thinks leads them: “We are the party of President Donald J. Trump.”