The NCC-1701 was a Federation Constitution class heavy cruiser that was in service with Starfleet in the mid to late 23rd century. In the course of her career, the Enterprise became the most celebrated starship of her time. The Enterprise was destroyed over the Genesis Planet in 2285 when Kirk activated the ship's auto destruct sequence o prevent the Enterprise from falling into the hands of the Klingons! Most famous Captain of the Enterprise was James T. Kirk!

Systems Alliance frigates, named after the great battles of human history, are among the larger warships capable of traveling between star systems in the interactive world of Mass Effect. Smaller combat support craft, fighters, and interceptors are used in a support role to the warships during combat. Fighters are a one-man craft used to perform close-range attacks on enemy ships. One of these is the SX3 Alliance Fighter.

Normandy is a Systems Alliance starship. She is a "deep scout" frigate, optimized for solo reconnaissance missions deep within unstable regions, using advanced stealth technology powered by an experimental drive core.