When the Clone Wars began, Dir'Nul refused to become a general in the Grand Army of the Republic, instead devoting her resources to tracking Kardem. After traveling to the planetPerilious, she killed three more Twi'leks, acting as Kardem. Six months later, as Dir'Nul investigated their murders, she was confronted by a male Jedi, whom she assumed was Kardem. After the Jedi defeated her in a lightsaber duel, Dir'Nul changed to the Kardem personality and attacked him with Force lightning. The Jedi explained that the Council had sent him after Dir'Nul, and then attempted to kill her. However, she intercepted the attack and killed the Jedi. After his death, Dir'Nul reverted back to her original personality and vowed to stop Kardem. Eventually, a bounty was placed on her alter ego of Kardem, and she was captured by the Mandalorianbounty hunterFeskitt Bobb.

Dir'Nul duels a Jedi sent by the Council to apprehend her on Perilious.

Six months later, while Dir'Nul was investigating the murders of the three Twi'leks, a robed man with a lightsaber revealed himself to her, and she attacked him, assuming he was Kardem. After a brief lightsaber duel, the man gained the upper hand and defeated Dir'Nul. As he informed her that he was going to bring her back to the Jedi Council, Dir'Nul reverted to the Kardem personality—who was unaware that he was Dir'Nul—and unleashed bolts of Force lightning against her attacker. After the Jedi used Dir'Nul's name while pleading with her to stop attacking him, Kardem told the man he was going to kill him. The man revealed that he was a Jedi and that he had been tracking Dir'Nul for six months. The Jedi ignited his lightsaber and used the Force to throw it at Dir'Nul, determined to bring her to the Council dead or alive. However, Dir'Nul, who was still mentally Kardem, used the Force to stop the lightsaber mid-flight and attacked the Jedi with more lightning. As Kardem was torturing the Jedi, he claimed that he did not know Dir'Nul and threw the lightsaber back at the Jedi, cutting him in half.[1]

Dir'Nul reverted back to her original personality following her attacker's death and was shocked to learn that Kardem had killed a Jedi. She vowed to stop Kardem no matter what it took, unaware that she was the one who had actually committed the crime.[1] A bounty was eventually placed on Dir'Nul's split personality of Kardem. The serial killer was captured by the Mandalorianbounty hunterFeskitt Bobb.[3]

The Human female Vydel Dir'Nul served the Jedi Order as a Jedi Knight. During her mission to protect an individual, she fell in love with the pilot Ash B'risko, willingly going against the Jedi Code. When she discovered B'risko in a Twi'lek dancer's arms, Dir'Nul was overcome with anger, and she killed both of them immediately. During the act of murdering B'risko and the Twi'lek, Dir'Nul unknowingly created an alter ego of a male Dark Jedi named Kardem. After burying B'risko, she desired answers and vengeance, and dedicated herself to capturing Kardem.[1]

Dir'Nul, under the personality of the Dark Jedi Kardem

Following the initiation of the Clone Wars, Dir'Nul was not interested in fighting for the Republic's politicians, whom she viewed as greedy and self-serving, and so refused to serve as a Jedi General. Neither Dir'Nul nor Kardem were aware of each other's existence.[1][2] During her search for Kardem, she continued her vendetta against Twi'lek females, violently murdering them as Kardem. After she reverted back to her normal personality, Dir'Nul would hear Kardem's voice, which would degrade Twi'leks and taunt her. After she was defeated in lightsaber combat by the male Jedi, she adopted the Kardem personality and began torturing him. When Kardem killed the Jedi, Dir'Nul reverted to her original personality and vowed to stop Kardem, regardless of how long it took and no matter what she had to sacrifice.[1]

Dir'Nul possessed the ability to move objects with the Force; she used this ability against the male Jedi sent by the Council to apprehend her. When Dir'Nul switched her personality to that of the serial killer Kardem, she possessed dark sideForce powers, including Force lightning. She used this power against numerous Twi'leks and against the male Jedi. When the Jedi dueled Dir'Nul, he was able to best her, and commented that she had let her skills at lightsaber combat deteriorate. After the Jedi threw his lightsaber at her, she was able to stop it mid-flight.[1] Dir'Nul herself wielded a lightsaber containing an orangecrystal.[1]