Warning – review of three Type 2 drugs

The European Medicines Agency (EMA) has started a review of canagliflozin, dapagliflozin and empagliflozin, which are diabetes medicines known as SGLT2 inhibitors. This was requested by the European Commission following several reports of diabetic ketoacidosis in patients on SGLT2 inhibitor treatment for Type 2 diabetes. EMA will now review all available data on the risk of diabetic ketoacidosis (DKA) with SGLT2 inhibitors and consider whether any changes are needed in the way these medicines are used in the EU.