USP15 inhibition appears to be the key to protection against neuroinflammation

Company

Corbin Therapeutics uses a proprietary drug discovery platform, to screen and identify novel inhibitors of ubiquitin-specific protease 15 (USP15). USP15 has been shown to regulate type 1 interferon and be key in the neuroinflammation pathogenesis. Corbin has established several collaborations for the development of USP15 inhibitors in neuroinflammation-based disorders, such as multiple sclerosis.

Toronto, ON, and Montreal, QC, May 19, 2017 – Proteorex Therapeutics Inc. (“Proteorex”), headquartered in JLABS @ Toronto, is excited to announce the start of their research and development collaboration with Montreal-based Corbin Therapeutics Inc. (“Corbin”). The collaboration will identify small molecules which efficiently inhibit an important and highly conserved ubiquitin protein. Proteorex will receive[…]

Montreal, Quebec – January 9, 2017 – AmorChem is pleased to announce the creation of Corbin Therapeutics, its third spin-off company focusing on a novel therapeutic approach to treat various inflammation-based diseases via inhibition of the ubiquitin carboxyl-terminal hydrolase 15 (USP15) enzyme. All rights to the USP15 technology initially held by AmorChem have been transferred[…]