Queensland's Opposition says the Crime and Misconduct Commission (CMC) should be investigating a senior health official accused of misconduct.

Queensland Health is conducting an investigation into claims of official misconduct by South-West Hospital and Health Service chief executive Graem Kelly.

Chairwoman Dr Julia Leeds has also stood aside from her position to avoid a conflict of interest while the investigation is conducted.

Opposition health spokeswoman Jo-Ann Miller says it is important the matter is reviewed independently.

"If Mr Kelly has been stood aside in relation to official misconduct you can't have the department of health investigating another department of health officer," she said.

"The CMC must be informed."

She says the reasons for the investigation should be made public.

"What we have here is a situation where the Government is simply not being transparent with the people of the south-west," she said.

"If Mr Kelly has been stood aside for matters such as official misconduct, it must be very serious."

The CMC says it will not confirm or deny if Mr Kelly is being investigated.

The LNP's Member for Warrego, Howard Hobbs, says he is surprised by the turn of events but he has assured residents health services are unaffected.

"The matter is under control and I need to assure the people of the south-west that in fact it is business as usual," he said.

"The deputy chairman, Lindsay Godfrey, is now in charge of the South-West Health Service. He has in fact been in Roma most of the week having meetings and getting things going, he will do an excellent job.

"We have the presumption of innocence. Those matters are being tested right now.

"I guess we have to wait until that matter is fully investigated.

"Let's hope that it is resolved sooner rather than later but I am surprised that it got to this stage."