Well thank god it's not only me, and no, still looking. I was told to try messing with settings in my Asio driver panel, and surprisingly, sometimes it works (temporarily). But it happens with both my M Audio cards, so i'm still convinced it's an Audition issue.

I also have been having this same issue....didnt notice it with version 2....but version 3 seem to be getting worse and driving me nuts...called many time to speak with Adobe...unsuccessfully. Clicks usually happen in the beginnibg of the recortding and I have been changing the start point to like 10 sec....in and seems to help. Also have tried buffer settings...asio updates...even replaced the power supply in the computer...when it got really bad....that seemed to stop it for awhile but not long. HELP!!!!

I resolved my issue by simply running 1 Echo audio firewire 12 track at a time...It appears that 2 - 12 tracks echo audio firewire 12 decks plugged into the same firewire card caused this problem.
Also a firewire card that echo recommends would be good to check as well. I havnt done that as of yet...but I believe 2 - 12 tracks plugged into the same card cause this poping issue for me. Try seperate cards for each unit it may solve the problem of running two 12 tracks together.

I resolved my issue by simply running 1 Echo audio firewire 12 track at a time...It appears that 2 - 12 tracks echo audio firewire 12 decks plugged into the same firewire card caused this problem.
Also a firewire card that echo recommends would be good to check as well. I havnt done that as of yet...but I believe 2 - 12 tracks plugged into the same card cause this poping issue for me. Try seperate cards for each unit it may solve the problem of running two 12 tracks together.

If you are experiencing pops and clicks in your audio, there are a number of things that you can try:

1. Install DPC latency checker. If you are experiencing, pops, clicks, and dropouts, this is the first step to take. Download this free utility and read the documentation carefully. After you run the utility, you may need to disable wireless, webcams, network cards, etc.

2. In Windows, go to System properties>Advanced>Performance and set to "Adjust to Best Performance."

3. If running FireWire from a laptop, you may need to purchase a third-party FireWire adapter. Some built-in FireWire chips do not perform well. If you are running more than one AudioFire, you may need to purchase an additional FireWire adapter.

4. Run the ASIO FireWire Analyzer (if you have an AudioFire product). It comes with every driver. Make sure you download the Readme as well as this contains the documentation for this utility.

5. Your buffer size may be too small or too high. Recommendations:

44.1K or 48K sample rate: buffer 128 <-> 256

88.2K or 96K sample rate: buffer 256 <-> 480

176.4K or 192K sample rate: buffer 512 <-> 960

6. Make sure your software and OS have the latest updates. Check for BIOS updates as well.

7. Trim your system down to the bare essentials. Initially, work with only one device. Do not add additional devices until your first device is running smoothly. Do not run any plugins. Add plugins only after everything else is running correctly.