Novalogic is planning an update to DF: Xtreme and the following has been taken from Novaworld2.com:

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For those technical enough to back up their current EXE and copy this one to the right folder, you can test it out for us. It's intended to be compatible with the current EXE and offers a few new features and improvements. Pending the test results, these changes will become available as a regular update.

This should work with all the Mods .... as it is only the exe file ...... Just remember to copy/backup the existing/original exe file to somewhere safe ..... and if it doesnt run properly or produces unwanted effects ..... Just copy the original exe back.