Red Fruit Oil high antioxidants prevent and break off the chain of free radicals and carcinogen compounds which can caused cancer and tumors. This is why Red Fruit Oil is believed to be a remarkable anti-cancer agent.

Beta-carotene and alpha tocopherol are the main compounds to overcome strokes, coronary heart disease and heart attacks. Beta-carotene removes the plaque accumulation from the arteries. It protect the blood circulation to the heart and brain. Alpha tocopherol decreases bad cholesterol (LDL) and increase the good cholesterol (HDL). Because of the synergy from both compounds in Red Fruit Oil, people who have problems with heart attacks and strokes may experience smoother breathing, improved blood pressure and a return of normal heartbeats.

The fatty acids in Red Fruit Oil have a unique characteristic of antibiotics and antiviral components. The high content of fatty acids particularly Omega 3 and Omega 9 in Red Fruit Oil can work very well in healing many diseases. The protein with unsaturated fatty acid in Red Fruit Oil can easily be digested by the human body as it increases your metabolism. In hepatitis cases, the liver can regenerate the broken liver cells faster.

Alternative Solution to Chemical Treatments

Natural Herbal treatments such as Red Fruit Oil are considerably better than chemically based pharmaceutical medicines. Red Fruit plant is safe to consume and with no significant side effect. As known, Red fruit Oil has become a daily part of the Papua communities and has been consumed for a long time with no side effects. The Papua community has used Red Fruit Oil to increase stamina and treat illnesses. Degenerative disease sufferers (for example diabetes, hypertension, uric acid, cancer and so forth) who consume pharmaceutical medicine for long period of time worry about the direct effect on their bodies, unlike Red Fruit Oil which has no side effects.

]]>http://pandanuslam.com/pandanous-conoideus-lam-red-fruit-oil-ingredients-are-an-excellent-source-of-antioxidants.html/feed/0Hello world! This is the Pandanus conoideus Lam Online Storehttp://pandanuslam.com/hello-world.html/
http://pandanuslam.com/hello-world.html/#commentsFri, 15 Jan 2016 18:45:29 +0000http://pandanuslam.com/wordpress/?p=1This online store specially for the Red Pandanus Fruit Oil of the Isle of New Guinea is intended to help anybody in the world who are suffering from various modern deadly diseases, particularly cancer and tumor.

We ara Papuans, from the Isle of New Guinea. We sell this red pandanus oil not because we want to make money, but our primary goal is to help as many people as possible in the world to get cured from various modern deadly diseases.

The health benefits of red palm oil mainly derive from the lycopene, tocotrienol and the alpha- and beta-carotene which it is so rich in. Firstly, what has so many natural health practitioners so excited is that use of this oil appears to increase overall mental acuity and cognitive function and at the same time reduces one’s chances of developing Alzheimer’s disease and other forms of dementia. With Alzheimer’s disease on the rise, use of this oil might prove to be particularly beneficial for the elderly. [http://blogs.naturalnews.com/top-reasons-red-palm-oil-miraculous/]

In addition, in June 2014 were certified as a functional food formally Korea FDA.

Because it is not water-soluble food, oxidative decomposition of the carotenoid does not occur.

And many other sources show that this fruit is beneficial for human society right now before it get taken away from people by multinational companies who have more concern on capital benefits rather than humanitarian aspect of this miraculous heavenly fruit of New Guinea.

We hope anybody interested in investing for humanity will contact us to act for the benefits of many human beings in the world.

ABSTRACT

Red fruit can commercially be obtained in extract (oil) form and capsulated oil (softcapsule). Within oil form, this product has lower tenacity and stability against light, heat, oxygen, and extreme environmental condition due to its content of easily degradable antioxidant group active compound. Red Fruit based essence product have been ever fortified into other food product, but only fortified into fried oil to improve carotene rate. One alternative to deal this problem refers to microencapsulation. Microencapsulation means the process of wrapping one certain central particle with other material to reach expected physical and chemical characteristic.

Microencapsulation method used in this research has been spray drying. Research was arranged by using Completely Randomized Design that organized in factorial pattern involving two factors. First factor includes coating materials (soybean protein isolate and Na-caseinate), while second factor entails red fruit oil proportion (20 %, 30%, and 40%).

The best treatment comes from treatment combination with Na-caseinate wrapping in proportion of 20% red fruit oil. Microcapsule with the best treatment has moisture content of 1.34 %, β-carotene of 580.42 μg/g, microcapsule size of 36,98 μm, microencapsulation efficiency of 95,59%, and yield of 93,37%. The process of red fruit oil microencapsulation with Na-caseinate in proportion of 20 % can be used as an alternative to facilitate distribution process, to increase product storability, and product fortification process into other food product.
Keywords: microencapsulation, red fruit, oil proportion, antioxidant stability, protein based coating

Portrait of the plant: Pandanus conoideus – the red fruit from the jungle for highly demanding skincare products

Botany

The name Pandanus refers to the plant genus of the pandans, better known as screw pine. Screw pine species grow as evergreen, tree or bush-shaped perennials. The genus Pandanus comprises more than 600 species which are native to the warmer countries of the eastern half of the southern hemisphere; most of them are found on the islands of the Indian Ocean.

One of the plant species in this family is called Pandanus conoideus. The Pandanus conoideus trees are native to the highlands and along coastal stretches of New Guinea. In their own languages, the local population calls the plant Buah Merah, Marita or Kuansu – which basically means “red fruit.” It grows as an evergreen, tree-shaped plant and can attain heights of up to 17 metres. It begins to branch out from the height of 5 to 8 metres above ground level. In view of those dimensions it is no surprise that the fruit can be up to 1 meter long. The multiple fruit has an elliptical shape with rounded off, blunt ends. It is surrounded and protected by carpels and has a diameter ranging from 10 to 15 cm. The weight of the pandan fruit ranges from about 2 to 3 kg. When ripe it is shiny and light-to-dark red in colour.

Screw palm Pandanus conoideus with fruit.

Breaking open the multiple fruit reveals a colourless interior composed primarily of light coloured cellulose, in which the red, oily fruit scales take the form of small oil-soaked pins. This component of the fruit is used for the extraction.

Industrial preparation of the drug

The plants for our Pandanus extract come from the highlands of the Indonesian part of New Guinea, where an adequate supply occurs naturally. After manual harvest, the large fruits are flown out of the highlands in cargo planes. In the lowlands, the fruit pins are then carefully removed and further processed in a warm-dry environment to form a bulk product. These measures reduce the risk of mould formation and retain the natural self-protective function of the oily-lipophilic ingredients. The resulting fruit pins, which measure 1 to 2 cm, meet our requirements for the raw material to be extracted.

What’s so special about this fruit?

In our search for new herbal active ingredients, the ethnobotanical approach which lead us to the Pandanus considered the following questions: How do other cultures use the fruit? What information is available to us from modern science today?

The native people of Papua are already familiar with Pandanus conoideus as a source of food. A natural dye (carotenoids) and a red oil are also obtained from the plant through pressing or cooking. Pandanus fruit is available on the markets of Indonesia, usually in the form of freshly pressed oil. Due to their traditional practises, the locals are convinced that the plant is suitable both as an eye and skin medication and to treat tumours and worms. The uses of the fruit and of its preparations range from food additives to remedies for gastrointestinal complaints, wound healing and dry skin. Based on the disease conditions defined in traditional applications, an anti-inflammatory potential can be derived as a characteristic. Our own scientific studies confirmed that Pandanus has an anti-inflammatory potential. For the Pandanus extract EVOR9476 which we produce, in-vitro tests on biomarkers for inflammations such as TNFα resulted in IC50 values of about 20 µg/ml. This test result is considered to be very potent and the activity is several times greater than that of the pressed Pandanus oils traditionally used.

EVOR9476 Pandanus extract

Finzelberg produces Pandanus extract EVOR9476 under GMP conditions. It contains the valuable ingredients of the complex, herbal, multi-component mixture. EVOR9476 is solid at room temperature and a homogenous, fatty, red oil at temperatures above 30°C. About 85% of the ingredient spectrum is known (fatty acids 83%, tocopherols 1%, carotenoids 0.8% and phytosterols 0.2%).

Modern, highly demanding skincare products with Pandanus EVOR9476

The ingredients of Pandanus extract EVOR9476 provide both nurturing and anti-inflammatory effects. This ideal combination of care and anti-inflammatory action opens up the possibility of using the extract in cortisone-free salves, creams and lotions specifically designed as an alterative treatment for neurodermitis and psoriasis.

We have successfully tested initial applications of a Pandanus cream preparation on neurodermitis patients. Our development department was also able to produce a decolourised extract for use in cosmetics-related applications.

EVOR9476 has already been processed into optimised, ready-to-use formulations which are available for the purposes of recipe development.

We offer a very good starting point for our business partners from the cosmetics industry:

Abstract

As functional food oil, red fruit (Pandanus conoideus Lam) oil has been believed by local community to threat several degenerative diseases like cancer. Red fruit oil (RFO) has commanded high price value in Indonesian market.

Therefore, the objective of the present study was to investigate several physico-chemical properties of RFO. Some parameters of RFO obtained from hexane and chloroform fractions have been evaluated. Such parameters include acid value, saponification value, anisidine value, conjugated dienes and trienes as well as p-anisidine value. Besides, absorptivity coefficient, fatty acid composition, and volatile compounds were also determined. Acid value and saponification value of RFO from chloroform fraction were higher than those in RFO from hexane fraction. In addition, RFO in hexane fraction has the higher iodine and anisidine values than that in chloroform fraction. Hexane is the best solvent to be used for analysis of RFO, as indicated by the highest absorptivity coefficient of RFO in hexane. The main fatty acid composed of RFO was oleic acid followed with palmitic acid. The main volatile compound present in RFO of hexane and chloroform fractions was 9-octadecenoic acid accounting of 41.57 % and 65.06 %, respectively.

ABSTRACT

Background: Oxidative stress has been implicated in pathogenesis and progression of many degenerative disorders including naturally occuring and chemically-induced diabetes mellitus. In addition to the increased production of free radicals, antioxidant defense systems are disturbed in diabetes mellitus. As a result, oxidative stress may cause oxidative damage of cellular, including Ii-cells of pancreas.

Objective: This study was aimed at investigating the effect of P. eonoideus Lam. on hypoglycemic activity of glibenclamide and histochemical changes in pancreatic islets.

Methods: Thirty male Rattus norvegicus rats were used in the study, and randomly selected. The animals were divided into two groups, each group consisted of 15 rats. Each group was devided into 3 subgroups, the first subgroups were subgroup 1; 2, 3 and the second was subgroup 4, 5, 6. Streptozotocin was injected intraperitoneally at a single dose of 60 mg/kg for induction of diabetes in the second group. Subgroup 1 and 4 did not receive anything, subgroup 2 and 5 received glibenclamide 0.09 g/kgBW/day and subgroup 3 and 6 received P. eonoideus Lam. 0.3 mLlkgBW/day and glibenclamide 0.09 g/kgBW/day. Rats were given P. eonoideus Lam. and glibenclamide everyday for 14 days. Hypoglycemic activity was evaluated in overnight fasted at day 1, 7 and 14, and the acute hypoglycemic activity was evaluated at time 0, 1, 2, 4, and 6 hour aher treatment at day 14. Blood was collected from orbital sinuses. Blood glucose level was determined using GOD-PAP method. At 15 day rat were killed, the pancreas was removed. The data was compared statistically using one-way analysis of variance (AN OVA) followed by post-hoc test and student unpaired t-test. For the analysis of immunohistochemical data, a non parametric test (Kruskal-Wallis) was used.

Results: The combination of P. eonoideus Lam. and glibenclamide produced significant reduction in blood glucose in the serial study at day 1, 7 and 14 and comparable with that of standard drug, also control groups in normal and diabetic rats. It also produced significant reduction of blood glucose in the serial study at time 0, 1, 2, 4, and 6 hour after treatment at day 14. Significant increasing histoscore, number and diameter of Langerhans islets were observed in P. eonoideus Lam. treated rats.

Abstract

Pandanus conoideus is an endemic plant of Papua, Indonesia, reported to be very rich in carotenoids. The purpose of this study was to develop method for the determination of carotenoids (α-cryptoxanthin, β-cryptoxanthin, α-carotene and β-carotene) in P. conoideus oil (PO) by high-performance liquid chromatography (HPLC). sing the proposed method in this research, carotenoids content of nine clones of PO were analyzed which ranged from 5.4-138.5 ng/mg for α-cryptoxanthin, 3.9-29.4 ng/mg for β-cryptoxanthin, 3.5-80.0 ng/mg for α-carotene, and 10.8-118.0 ng/mg for β-carotene. Our results showed that four carotenoids content was very small as compared to total carotenoids content (3027-19959 ng/mg). This suggests that those four carotenoids were not a major component of the PO carotenoids. Using the principal component analysis, nine clones of P. conoideus can be grouped based on the proximity of its carotenoid content into group A (Monsor, Mbarugum, Himbiak, Monsrus and Memeri), group B (Menjib Rumbai), and group C (Edewewits, Hibcau and Hityom).

Name of Plant

Classification of Plants

Division : Spermatophyta

Class: Angiospermae

Subclass : Monocotyledonae

Order : Pandanales

Family : Pandanaceae

Genus : Pandanus

Species : Pandanus conoideus Lam.

Description of Plant

Red fruit cultivars distinguished based on the size of the fruit, fruit color and fruit shape. Cultivars are known among other is a short red cultivars, red-brown, red being, long red, long yellow, and yellow short (Sadsoeitoeboen 2003;Limbongan dan Uhi 2005). Generally, up to 10-year-old plants, fruiting at the age of 3-5 years, and the age of 3-4 months until harvest fruit. Plants grow clumped with a density of 12-30 individuals per clump. Red fruit plants have roots tunjang 0.20 to 3.50 m, root circumference 6-20 cm, brown with white spots, spherical shape, and surface spiny. The number of roots in a clump ranged between 11-97. The main trunk circumference ranged between 20-40 cm, plant height from 2 to 3.50 m. The stem is brown with white spots, round, beam vessels does not seem obvious, hard, direction grow vertically or upright, branching number 2-4, and prickly surface. Leaves measuring 96 cm x 9.30 cm to 323 cm x 15 cm. The tip of spear-shaped leaves (micronate), perforated base (cut off), bottom edge of the leaf and the leaf barbed bone. Single leaf composition with alternate leaf arrangement. Leaves pliable, dark green, parallel vein patterns, no petiole (sessile), and not flavorful. Flowers like jackfruit flowers with reddish color. Fruit length measuring 68-110 cm, diameter 10-15 cm, cylindrical, blunt tip, and a base such as heart. While still young, pale red fruit, and turned into a red brick while old. There are three types of red fruit superior, that are red fruit Mbarugum, Maler, and Magari. Several criteria superior red fruit that are: 1) number of fruit 5-10 grains / clump, 2) soft pith, 3) large fruit size (diameter 10-15 cm) and large (60-110 cm), 4) results essence (oil) high, average 120 ml/kg piece, 5) number of tillers many, that is 5-10 tillers / clump, and 6) a lot of number of roots tunjang, that is 11-97 roots / clumps, thus able to supply more nutrients, absorb oxygen from the air, and strengthen the plants stand upright (Lebang dkk., 2004).

Habitat and Deployment

Red piece plants were found in Papua, Papua Nugini. and began sporadically planted in some areas such as Maluku, Sulawesi, Kalimantan, Jawa, and Sumatera. These plants can be grown on the plains to a height of 2,500 m above sea level, with low soil fertility, acid to moderately acid (pH 4,30- 5,30), with shade 0-15%, and grow in clusters around the flow of the river (Nainggolan, 2001;Hadad dkk., 2005).

Usefulness in society

Red fruit is used by the public as a food flavoring of high nutritional value because it contains beta-carotene, natural colorant that do not contain heavy metal and harmful microorganisms. Besides that, red fruit functioned as a supporting daily staple food, and cure various diseases that are cancer, HIV, malaria, cholesterol, diabetes mellitus, gout and osteoporosis. Dregs of red piece can also be used as poultry feed while the roots can be made rope, binding and mats then the trunk as the board (Moeljopawiro dkk., 2007a;Limbongan dan Malik, 2009).

Chemical Ingredients

Chemical constituents of red fruit oil (Pandanus conoideus Lam.) which is widely used by the public are as follows:

Anticancer research

Red fruit has anticancer effects on ovarian cancer cells, breast (T47D cell), colon cancer cells (CC531 cell) where the effect on ovarian cancer cells and colon cancer cells is greater than in breast cancer cells. IC50 red fruit juice in colon cancer cell is 200 ppm whereas in breast cancer cell is 600 ppm. Anticancer activity of this red fruit juice was greater than the chemotherapy agent doxorubicin. It is shown through research of methanol extracts of red fruit types Mbarugum and chloroform extracts of red fruit Maler types that are more cytotoxic on T47D breast cancer cells compared doxorubicin and structure of bioactive compounds in the extracts were hexadecanoic acid and 9-octadecanoic acid. The mechanisms mediating the cytotoxic effects of this red fruit juice is apoptosis. In addition to the cytotoxic effects, antiproliferative effect was also demonstrated through the doubling time test at 0, 24, 48 and 72. This antiproliferative potential describe the inhibition of cancer cells growth by red fruit juice (Moeljoprawiro dkk., 2007a;Moeljoprawiro dkk., 2007b)

Research in in vivo through histological observations through histological observations dimetilbenz(a)antrasen (DMBA) shows that red fruit juice has the ability inhibit the growth of cancer at doses 0,21 mL/ 200 g BB whereas at higher doses an increase in tumor growth. This is probably due by high levels of β-carotene in red fruit juice, thus increasing the damage of tissue and tumor growth in lung. Based on the research that has been done regarding the effect of β-carotene on the growth of lung tumors tested on ferrets, stated that giving β-carotene in high doses (2,4 mg/kgBB per day) for six months can cause development of alveolar cell proliferation and metaplasia keratinization squamous(Wolf, 2002;Munim dkk., 2006).

The content of red fruit juice that has anticancer activity is β -cryptoxanthin which is a provitamin A. Kinds of other carotenoids such as a-carotene and β-carotene did not affect the growth of cancer cells even β-carotene at high doses increase the mortality of lung cancer patients in the USA when compared with patients with lung cancer who did not receive β-carotene and vitamin A synthetic (Waspodo dan Nishigaki, 2007).

Testing of red fruit oil on A549 cells (lung cancer cell) shows that at concentrations greater than 500 mg/ mL occurs A549 cell growth inhibition. From 500 mg of the red fruit oil contained 0,015 µg β-cryptoxanthin so that the concentration of β -cryptoxanthin relatively little has been able to inhibit growth of lung cancer cells and this was confirmed with clinical trials against 18.244 men Shanghai who smoke. In testing it was found that increased levels ofβ-cryptoxanthin in blood decreased the incidence of lung cancer while others micronutrient such as a -carotene, β-carotene, Vitamin E had no effect on the incidence of lung cancer in smokers (Waspodo dan Nishigaki, 2007).

Research of β-cryptoxanthin of orange peel on liver cancer cells turned out to prove his ability as an anticancer in other types of cancer, other than lung cancer. Based on the mechanism of action of carotenoids as a nutrient in Retinoic Acid Receptors (RARs) it is possible β-cryptoxanthin work through the RARs various factors that affect gene transcription both on the type of lung cancer and other cancers (Waspodo dan Nishigaki, 2007).

Fatty acid content reaches 94% of red fruit oil has proved similar to the composition of fatty acids of animals compared to the fatty acid composition of plant. Types of fatty acids are not included in the class of trans fatty acids so the red fruit oil will not cause obesity, atherosclerosis, diabetes mellitus and breast cancer (Waspodo dan Nishigaki, 2007).

Was published in Indonesia, it is Buamera books of Indonesian version.
In Indonesia, it is expected to become the foundation of this Buamera research.
Embassy of the Republic of Indonesia and the ASEAN Center (Tokyo, Osaka) has been placed in.

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