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Doctor insights on:
Lioresal Medication

1

Lioresal (baclofen):
is classified as a centrally acting skeletal muscle relaxant, it is commonly used in the management of paroxysmal neuralgias such as trigeminal neuralgia. Lioresal (baclofen) should never be discontinued suddenly after prolonged use because of the risk of developing anxiety, hallucinations and tachycardia.
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Baclofen is used to reduce discomfort related to "muscle spasms" from a variety of causes. It is commonly used to treat spasticity - which is a constant "muscle spasm" commonly associated with prior brain and spinal cord injury.
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4

Nicotine/Lioresal:
I don't believe there are any bad interactions - the nicotine in the patch is like smoking a pack of cigarettes. I would go ahead and use the two. If you do start to have any side effects - you can easily remove the nicotine patch.
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6

Liorisal + Motival:
Motival is a combination of a major tranquilizer and a tricyclic antidepressant. This combination alone can cause drowsiness. The muscle relaxant Liorisal will almost always cause drowsiness. I think you know where I'm heading here. If the same doctor did not prescribe both drugs, be sure each doctor is aware.and approves. Don't drive until you see how you are affected by the combo. NO ALCOHOL
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8

Critique:
Trivastal, a newer Dopamine agonist, is not available in the usa, but might be a choice. Sifrol, pramipexole, is likely your safest and best starting drug. There is no role for lioresal, (baclofen) and Artane is literally "poison" and is not used in the usa. Choose the doc who recommended sifrol.
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10

Yes:
Several studies have shown that Baclofen (liorisal®) can reduce or eliminate alcoholwithdrawal. This is not surprising, because this drug is a direct gaba-acting agent and gaba is the neurotransmitter that is also affected by benzodiazepines like valium and librium, and work in withdrawal. However, it can cause physical dependence as well if used for prolonged periods.
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11

It's ok:
It is a medicine chiefly used as a muscle relaxer for those with spastic muscle conditions. Since drowsiness is one of its side effects, I can see how it might help with sleep if taken at night. But that is not its primary indication.
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12

Indications:
Baclofen is a drug originally indicated for treatment of spasticity, and has been used off label with some pain conditions such as trigeminal neuralgia. Am unaware of any direct benefits in alcoholism unless the above complications have occurred. Since it is metabolized through the liver, might make certain that liver has not been damaged.
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If possible, yes:
It is helpful if your Doctor agrees-let them know and discuss with them, as if you start both meds at the same time, you may not know which one genuinely helps and or if you get an adverse reaction/side effect, you would not know which one caused it, etc. Best wishes.
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14

Doubt it:
None of the medications you take directly increase your blood pressure. Of course all medication are metabolized in liver and excreted in kidney so if you have medical issues with your kidneys then you have to have a discussion with your doctor who can give you specific information good luck.
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16

Common side effect:
Unfortunately baclofen does cause constipation as a side effect in many patients. Cases of intestinal obstruction have been linked to the use of baclofen as well. My recommendation is to either reduce the dose or to visit your GP and change over to an alternative medication such as Orphenadrine. You can also try increasing your fluid and fibre intake as well as taking mild laxatives.
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Complicated:
A little unusual to say that you feet/ankles are painful with swelling...swelling is common but often painless. Most serious causes of swelling would be heart failure (unusual at your age), kidney, liver disease. Could be problems with veins (poor valves causing sluggish return of blood to heart). Reviewed your meds...see no reason to suspect them. Need good evaluation...start with primary care
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21

No:
Baclofen acts on the same receptors as do benzodiazepines, which may be tested for in some kinds of tests, but it is not tested for in usual test kits, and is chemically unrelated to those medications.
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Possibly:
Clonazepam is a possibility but is a controlled substance and is not prescribed unless you really have problems with he baclofen. It causes dependence and is pretty hard to wean from.
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26

Any doc could :
Prescribe this but it is the rare doc who is aware of baclofen. I use it for stimulant and opioid issues. However, it is not completely safe and about 0.2-0.5% lose control c/w a syndrome caused by any tranquilizer.
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31

Baclofen:
Although baclofen is classified as a centrally acting skeletal muscle relaxant, it is commonly used in the management of paroxysmal neuralgias such as trigeminal neuralgia. Baclofen is a GABA agonist that is considered a first-line analgesic for this type of pain
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34

Yes:
Baclofen is useful as an agent to treat spasm or increased tone. The medication can be used in oral form and in cases of extreme spasticity, it is administered into the spinal fluid. This is usually done with a surgically implanted pump which can be refilled percutaneously (through the skin with a needle).
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35

ONLY as prescribed.:
The main danger of recreational use is high risk of overdose, as the substance takes few hours to onset during which the user may take more Baclofen thinking that he or she did not consume enough. Other common side effects include organ damage and powerful narcolepsy (uncontrolled sleepiness) by the end of experience. Do not used as recreational drug.
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36

In dose range:
With Baclofen always check with your doctor on changing doses as stopping abruptly, changing abruptly can cause side effects that could be hazardous. But 20mg is within the recommended dose range.
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38

Possible BUT:
Both drugs can promote drowsiness and dizziness, and together may result in difficult function. If used together might need to carefully titrate doses to tolerance. Work closely with your doctor.
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39

Better not:
both drugs act centrally and may cause CNS / psychomotor depression, you may want to hold or reduce the hydrocodone while on baclofen. Both are Rx meds, hydrocodone is controlled, so you also want to check with your prescriber, best wishes
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