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Latest & greatest articles for migraine

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on migraine or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on migraine and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Effectiveness of Vitamin B2 versus Sodium Valproate in Migraine Prophylaxis: a randomized clinical trial. 26516440 2015 10 30 2015 10 30 2017 02 20 7 6 2015 Oct Electronic physician Electron Physician Effectiveness of Vitamin B2 versus Sodium Valproate in Migraine Prophylaxis: a randomized clinical trial. 1344-8 10.14661/1344 Migraine headache is a prevalent periodical and neurological impairment that is associated with functional disorders. Regarding the side effects of available medications (...) , research is continuing in an effort to identify new, effective pharmaceutical regimens with limited side effects. The aim of this study was to compare the effectiveness of vitamin B2 versus sodium valproate in migraine prophylaxis. This was a single-blind clinical trial conducted on 90 migraine patients in two parallel groups. The first group underwent vitamin B2 treatment (400 mg/day) for three months, and the second group was treated with sodium valproate (500 mg/day). The patients were examined

Reduced efficacy of sumatriptan in migraine with aura vs without aura 25841032 2015 05 05 2015 07 13 2015 05 05 1526-632X 84 18 2015 May 05 Neurology Neurology Reduced efficacy of sumatriptan in migraine with aura vs without aura. 1880-5 10.1212/WNL.0000000000001535 To determine whether acute migraine treatment outcome is different in migraine with aura compared with migraine without aura. We examined pooled outcome data for sumatriptan treatment of migraine with and without aura from (...) free was 5.8 for attacks without aura and 5.0 for attacks with aura. This post hoc analysis of pooled data from multiple randomized trials indicates that sumatriptan is less effective as acute therapy for migraine attacks with aura compared with attacks without aura. In the single study of inhaled DHE, the treatment had similar efficacy for migraine attacks with and without aura. Different responses of migraine with vs without aura to acute therapies may provide insight into underlying migraine

Feverfew for preventing migraine. BACKGROUND: This review is an update of a previously published review in the Cochrane Database of Systematic Reviews on 'Feverfew for preventing migraine' (2004, Issue 1). Feverfew (Tanacetum parthenium L.) extract is a herbal remedy, which has been used for preventing attacks of migraine. OBJECTIVES: To systematically review the evidence from double-blind randomised controlled trials (RCTs) assessing the clinical efficacy and safety of feverfew (...) monopreparations versus placebo for preventing migraine. SEARCH METHODS: For this updated version of the review we searched CENTRAL, MEDLINE, EMBASE and AMED to January 2015. We contacted manufacturers of feverfew and checked the bibliographies of identified articles for further trials. SELECTION CRITERIA: We included randomised, placebo-controlled, double-blind trials assessing the efficacy of feverfew monopreparations for preventing migraine in patients of any age. We included trials using clinical outcome

Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) for the prevention of migraine in adults. BACKGROUND: This is an updated version of the original Cochrane review published in 2005 on selective serotonin reuptake inhibitors (SSRIs) for preventing migraine and tension-type headache. The original review has been split in two parts and this review now only regards migraine prevention. Another updated review is under development to cover (...) tension-type headache.Migraine is a common disorder. The chronic forms are associated with disability and have a high economic impact. In view of discoveries about the role of serotonin and other neurotransmitters in pain mechanisms, selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) have been evaluated for the prevention of migraine. OBJECTIVES: To determine the efficacy and tolerability of SSRIs and SNRIs compared to placebo and other active

Propofol for the Abortive Treatment of Adult Migraine Headache in the Emergency Department "Propofol for the Abortive Treatment of Adult Migraine Headache in the " by Amber Kuklinski < > > > > > Title Author Date of Award Summer 8-8-2015 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor Mark Pedemonte, MD Rights . Abstract Background: Migraine headache is a debilitating disorder that is difficult to manage and is often treated (...) in the emergency department (ED). Many standard abortive therapies used in the ED have mixed efficacy and lead to unsatisfactory results. Propofol is a proposed treatment for acute migraine with the potential to have better efficacy than standard ED abortive medications. This review evaluates propofol’s effectiveness at reducing pain severity and headache recurrence in adult patients with migraine headache when compared to typical abortive therapies. Methods: An exhaustive search of medical literature

Homeopathic remedies in the treatment of migraine and osteoarthritis: evidence note 53 Homeopathic remedies in the treatment of migraine and osteoarthritis: evidence note 53 Search the full site Search keywords Our on-going projects: Evidence note 53 Evidence note 53 Contact the SHTG team Contact Healthcare Improvement Scotland with any SHTG questions: Email: Lead Health Services Researcher Lead for SHTG SHTG Project Officer Evidence note 53 Are homeopathic remedies clinically and cost (...) effective in the treatment of migraine and osteoarthritis? Downloads Key points Published systematic reviews of homeopathy for migraine and osteoarthritis provide limited evidence on clinical effectiveness compared with standard care. Homeopathy for migraine has not been compared with active treatment in randomised controlled trials (RCTs), and only one of four RCTs found homeopathy to be superior to placebo. In three RCTs, drug treatments for osteoarthritis had similar or better effects on pain than

Curelator Headache? digital platform for adults with migraine Curelator Headache™ digital platform for adults with migraine Curelator Headache™ digital platform for adults with migraine NIHR HSC Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation NIHR HSC. Curelator Headache™ digital platform for adults with migraine. Birmingham: NIHR Horizon (...) Scanning Centre (NIHR HSC). Horizon Scanning Review. 2014 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Humans; Migraine Disorders Language Published English Country of organisation England English summary An English language summary is available. Address for correspondence NIHR Horizon Scanning Centre, School of Health&Population Sciences, University of Birmingham, Public Health building, Edgbaston, Birmingham, B15 2TT. Tel: +44 121 414 7831 Email: nihrhsc

Does caffeine help with migraines? Does caffeine help with migraines? » Morsels of Evidence Search Evidence based medicine for general practitioners « » Sep 05 Does caffeine help with migraines? Categories: , , , by Journal reference: Derry CJ, Derry S, Moore RA. Caffeine as an analgesic adjuvant for acute pain in adults. Cochrane Database of Systematic Reviews 2012, Issue 3. Art. No.: CD009281. Link: Published: 14 March 2012 Evidence cookie says… Oral caffeine (100 mg) as a single dose may (...) have a modest effect on acute pain (including migraine) when used as an adjuvant to oral analgesia (including paracetamol). There are significant uncertainties in the evidence-base and this finding should be treated cautiously. There is an absence of evidence for repeated doses of caffeine. Clinical scenario Matt, a 35-year-old lawyer mentioned in passing that when he had a migraine, he took a couple of tablets of paracetamol with a double-shot espresso. Caffeine is also available in combination

Maxillary artery ligation for the treatment of cluster or migraine headaches: clinical effectiveness and guidelines Maxillary artery ligation for the treatment of cluster or migraine headaches: clinical effectiveness and guidelines Maxillary artery ligation for the treatment of cluster or migraine headaches: clinical effectiveness and guidelines CADTH Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality (...) of this assessment has been made for the HTA database. Citation CADTH. Maxillary artery ligation for the treatment of cluster or migraine headaches: clinical effectiveness and guidelines. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). Rapid Response - Summary of Abstracts. 2014 Authors' conclusions One relevant non-randomized study regarding the use of maxillary artery ligation for the treatment of cluster headaches was identified. No relevant health technology assessment reports

OnabotulinumtoxinA (Botox - Allergan Inc.) indication: chronic migraine OnabotulinumtoxinA (Botox - Allergan Inc.) indication: chronic migraine OnabotulinumtoxinA (Botox - Allergan Inc.) indication: chronic migraine CADTH Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation CADTH. OnabotulinumtoxinA (Botox - Allergan Inc.) indication: chronic (...) migraine. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). CDEC final recommendation. 2014 Authors' conclusions The Canadian Drug Expert Committee (CDEC) recommends that onabotulinumtoxinA (OA) not be listed for the management of chronic migraine. Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Botulinum Toxins, Type A; Chronic Disease; Migraine Disorderss Language Published English Country of organisation Canada Province or state Ontario English summary

Treating migraine attacks: new evidence to guide choices Treating migraine attacks: new evidence to guide choices - Evidently Cochrane Search and hit Go By June 6, 2014 // Hildegard von Bingen Image found at www.catholicworldreport.com Trust a doctor to put a dampener on things. Just imagine, there you are having visions where “Heaven was opened and a fiery light of exceeding brilliance came and permeated my whole brain, and inflamed my whole heart and my whole breast, not like a burning (...) but like a warming flame, as the sun warms anything its rays touch.” This was the lot of a 12th century abbess, Hildegard von Bingen. According to neurologist Oliver Sacks, the poor dear was just experiencing migraines. Whether Hildegard was a migraine sufferer remains speculative and this could be a case of historical over diagnosis. I’m not convinced she would have wanted to put a stop to these experiences, but if you are prone to migraines I’m sure you’ll want to know what might work for you