The preliminary results from a clinical trial, known as CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial), were presented at the 2010 American Stroke Association International Stroke Conference in San Antonio and found CAS to be as safe and effective as surgical carotid endarterectomy.

Illness proxies were, for angioplasty, CABG, and pacemaker implantation, zip code-specific deaths per 10,000 residents with primary cause of death listed as ischemic heart disease; for carotid endarterectomy, incidence of death due to cerebrovascular disease; for hysterectomy, incidence of cervical and uterine cancer; and for mastectomy, incidence of breast cancer.

Carotid endarterectomy is a surgical procedure which removes an unwanted build-up of inflammatory cells, cholesterol and cellular debris known as plaque from the inner lining of the major arteries in the neck which supply blood to the brain.

For the second study, results showed that out of the total 181,200 carotid endarterectomy procedures (CEA) and 12,485 carotid artery stenting procedures (CAS), carotid artery stenting was associated with significantly higher costs than carotid endarterectomy.

In particular, he hopes the identification of lucent defects will lead to better-informed decisions about whether or not to resort to carotid endarterectomy surgery--which he says currently is overused--to clean out carotid arteries (SN: 2/8/86, p.

Food and Drug Administration (FDA) approved the RX ACCULINK Carotid Stent System for the treatment of patients with carotid artery disease who are at standard risk of adverse events from carotid endarterectomy (surgery).

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