Background: Retinal optical coherence tomography (OCT) permits quantification of retinal layer atrophy relevant to assessment of neurodegeneration in multiple sclerosis (MS). Measurement artefacts may limit the use of OCT to MS research. Objective: An expert task force convened with the aim to provide guidance on the use of validated quality control (QC) criteria for the use of OCT in MS research and clinical trials. Methods: A prospective multi-centre ( n = 13) study. Peripapillary ring scan QC rating of an OCT training set ( n = 50) was followed by a test set ( n = 50). Inter-rater agreement was calculated using kappa statistics. Results were ...