CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA - An invention relating to therapeutic pharmacological agents and methods to chemically induce intracellular hyperthermia and/or free radicals for the diagnosis and treatment of infections, malignancy and other medical conditions. The invention relates to a process and composition for the diagnosis or killing of cancer cells and inactivation of susceptible bacterial, parasitic, fungal, and viral pathogens by chemically generating heat, and/or free radicals and/or hyperthermia-inducible immunogenic determinants by using mitochondrial uncoupling agents, especially 2,4 dinitrophenol and, their conjugates, either alone or in combination with other drugs, hormones, cytokines and radiation.

Use of a Blood-Flow Decrease Preventing Agent in Conjunction With Insufflating Gas - A blood-flow decrease preventing agent is used to negate or reduce the decreased oxygen delivery in abdominal organs caused by insufflating gas. Preferably a gas is delivered into the abdominal cavity consisting essentially of the insufflating gas and the blood-flow decrease preventing agent. Very preferably, a gas is used consisting essentially of carbon dioxide as the insufflating gas and ethyl nitrite as the blood-flow to abdominal organ decrease preventing agent.

COMPOSITION IN FORM OF A GEL FOR THE VIRUCIDAL DISINFECTION OF MAMMALIAN SKIN - The present invention describes a composition in form of a gel for the virucidal disinfection of mammalian skin comprising 71 to 95 weight percent of a C1 to C3 monoalcohol, 0.01 to 1 weight percent thickener and wherein the composition has a viscosity range of from 3000 to 19000 mPas measured at 20° C. with spindle LV3 at a speed of 2.5 rpm. Furthermore, the invention describes a method for virucidal disinfection of skin.

08-01-2013

20160081333

High Alcohol Content Sanitizer - An embodiment relates to an antimicrobial sanitizing composition in the form of a gel or cream that contains an alcohol in an amount of at least 55% by weight. The sanitizer is capable of disinfecting and providing prolonged antimicrobial property to a variety of surfaces, including the skin, without causing, drying, cracking, redness or irritation. In addition to alcohol, the sanitizer contains an anionic phospholipid in a controlled concentration as well as components conventionally found in skin creams and gels such as emulsifiers, emollients, moisturizers, rheology modifiers, and neutralizers. The anionic phospholipid enables use of the composition without the user experiencing dryness or irritation and the feeling of a greasy and unpleasant residue on the skin following use.

03-24-2016

20150320041

NON-AEROSOL FOAMING ALCOHOL HAND SANITIZER - A non-aerosol, foaming high alcohol content hand sanitizer is provided which has excellent antimicrobial activity and tolerance for organic load and excellent residual activity, as well as enhanced moisturization and skin-feel properties over currently marketed alcohol-based sanitizers. The inventive composition achieves an unexpectedly large amount of quality, stable foam even in the presence of significant quantities of skin conditioning agents through the use of novel silicone surfactants and achieves enhanced and prolonged antimicrobial efficacy through the combination of high alcohol content and activity enhancing components.

11-12-2015

20140094525

FOAMABLE ALCOHOLIC COMPOSITION - A foamable composition is provided that includes at least 40 weight percent alcohol, based upon the total weight of the alcoholic composition; and a foaming surfactant selected from the group consisting of silicone quats.

ALCOHOL-CONTAINING COMPOSITIONS USEFUL AS SOLID FUELS AND PROCESSES FOR THEIR MANUFACTURE - There is provided a composition comprising: (a) from about 60 to about 98% by weight of one or more alcohols; (b) from about 0.5 to about 20% by weight of one or more alkyl cellulose derivatives, wherein each alkyl is optionally substituted with one or more OH, O-alkyl, O-hydroxyalkyl and/or O-alkoxyalkyl; (c) from about 1 to about 25% by weight of one or more carboxylic acid salts; and (d) from 0 to about 30% by weight of water. There is also provided uses, processes for manufacture, methods and products relating to the same.

High Alcohol Content Sanitizer - This invention relates to an antimicrobial sanitizing composition in the form of a gel or cream that contains an alcohol in an amount of at least 55% by weight. The sanitizer is capable of disinfecting and providing prolonged antimicrobial property to a variety of surfaces, including the skin, without causing, drying, cracking, redness or irritation. In addition to alcohol, the sanitizer contains an anionic phospholipid in a controlled concentration as well as components conventionally found in skin creams and gels such as emulsifiers, emollients, moisturizers, rheology modifiers, and neutralizers. The anionic phospholipid enables use of the composition without the user experiencing dryness or irritation and the feeling of a greasy and unpleasant residue on the skin following use.

08-23-2012

20100184867

USE OF ACTIVE AGENTS FOR STIMULATING THE EXPRESSION OF FN3K AND/OR FN3K RP FOR COMBATING AGEING OF THE SKIN - A cosmetic process for caring for human skin, which is intended for preventing and/or combating at least one sign of ageing of the skin or the ‘orange peel’ appearance of the skin, includes the topical application to the skin of a composition containing at least one active agent for stimulating the expression of FN3K and/or FN3K RP. The use of this active agent for preventing and/or combating at least one sign of ageing of the skin or the ‘orange peel’ appearance of the skin associated with cellulite is also disclosed.

METADICHOL.RTM. LIQUID AND GEL NANOPARTICLE FORMULATIONS - The present invention provides methods of regulating physiological and metabolic parameters and of treating diseases by administering metadichol to a subject in need of such regulation and/or treatment. Metadichol can be administered as a liquid or gel formulation.

METHODS AND COMPOSITIONS FOR USE WITH GEL DISPENSERS - A method is provided for reducing the frequency of mis-directed output of hydroalcoholic gel from a dispenser. A method of reducing the formation of coagulated gel deposits, and dispensable hydroalcoholic gel compositions are also provided.

MULTI-PURPOSE HAND DISINFECTANT - A multi-purpose hand disinfectant and in particular, a hand disinfectant which meets the FDA (Food and Drug Administration) requirements for use both as an antiseptic handwash or health-care personnel handwash drug product and as a surgical hand scrub drug product is described herein.

HEPATITIS A VIRICIDE - The invention relates to agents which combat the hepatitis A virus, containing only minimal amounts of chlorine-containing and/or chlorine cleaving active ingredients, or none of said substances. The inventions also relates to the use of these agents and to a method for their production.

ALCOHOLIC PUMP FOAM - An alcoholic foam composition, which can be dispensed as a foam via a pump-foam system contains a) at least 52 to ≦99 wt % of an alcohol or mixture of alcohols, b) a surfactant or a surfactant mixture, c) at least one polyalkylene glycol, d) optionally, at least one foam stabilizer, e) optionally, at least one member selected from the group consisting of cosmetic auxiliaries, adjuvants, active ingredients, and mixtures thereof, and f) optionally water. The surface tension of component b) lies in the range of ±15 dyn/cm of the surface tension of component a) or corresponds to the surface tension of component a), and the sum of components a) to f) is 100 wt % relative to the total quantity of the foam composition.

03-18-2010

20140296350

METHOD FOR THE FORMULATION OF HAND SANITIZER - A hand sanitizer composition that provides effective skin sanitization and exhibits low flammability, while containing sufficient humectant for moisturization of the skin includes an alcohol selected from the group consisting of alcohol(s) containing 4 to 6 carbon atoms in an amount of from about 10% to about 60% by volume, and one or more humectants present in an amount of from about 10% to about 80% by volume.

10-02-2014

20140364509

ALCOHOL BASED SANITIZER WITH IMPROVED DERMAL COMPATIBILITY AND FEEL - Applicants have identified a critical skin benefit package that can be used in liquid alcohol sanitizing compositions that provides lower amounts of skin conditioners in combination with a specific ratio of different emollients that provide improved skin health with chronic repeated use. The package also provides improved skin feel with without a tacky residue upon drying.

ALCOHOLIC PUMP FOAM - An alcoholic foam composition, which can be dispensed as a foam via a pump-foam system contains a) at least 52 to ≦99 wt % of an alcohol or mixture of alcohols, b) a surfactant or a surfactant mixture, c) at least one polyalkylene glycol, d) optionally, at least one foam stabilizer, e) optionally, at least one member selected from the group consisting of cosmetic auxiliaries, adjuvants, active ingredients, and mixtures thereof, and f) optionally water. The surface tension of component b) lies in the range of ±15 dyn/cm of the surface tension of component a) or corresponds to the surface tension of component a), and the sum of components a) to f) is 100 wt % relative to the total quantity of the foam composition.

08-07-2014

20120136069

Alcoholic Pump Foam - An alcoholic foam composition, which can be dispensed as a foam via a pump-foam system contains a) at least 52 to ≦99 wt % of an alcohol or mixture of alcohols, b) a surfactant or a surfactant mixture, c) at least one polyalkylene glycol, d) optionally, at least one foam stabilizer, e) optionally, at least one member selected from the group consisting of cosmetic auxiliaries, adjuvants, active ingredients, and mixtures thereof, and f) optionally water. The surface tension of component b) lies in the range of ±15 dyn/cm of the surface tension of component a) or corresponds to the surface tension of component a), and the sum of components a) to f) is 100 wt % relative to the total quantity of the foam composition.

Disinfectant and sanitizer for cosmetics and cosmetic tools - The present invention provides a disinfectant and sanitizer composition for application to cosmetics and cosmetic tools, which composition comprises: ethyl alcohol; and one or more conditioners selected from the group consisting of isopropyl palmitate, caprylic triglyceride, capric triglyceride, isopropyl myristate, and alkylbenzoate.

01-07-2010

20110166238

Cobbs Company Aftershave Gel for Men & Women - Cobbs Company Aftershave Gel is a cosmetic product designed to moisturize and maintain healthy looking skin. Cobbs Company Aftershave Gel can be applied to the skin area after shaving. Cobbs Company Aftershave Gel contains water, white petroleum jelly, and isopropyl alcohol. These three ingredients should only be mixed, sold, and used through the authorization of Cobbs Company.

ALCOHOLIC COMPOSITIONS WITH IMPROVED PROPERTIES AND METHODS FOR EVALUATING INTERACTION OF THE COMPOSITIONS WITH SURFACES - A method is provided for measuring the interaction of a disinfecting composition with a floor wax. The method include coating a surface with floor wax, allowing the coating to dry, applying a selected amount of disinfecting composition to the coated surface, and measuring, after a pre-determined amount of time, the tack of the surface, by using a controlled force measurement inverted probe machine. A detectable amount of tack indicates that the disinfecting composition has interacted with the floor wax. Alternatively, any tacky residue on the dried product surface may be sampled and analyzed by Fourier transform spectroscopy. Absorption at a wavelength associated with the floor wax indicates that the product has interacted with the floor wax. A foamable disinfecting composition having reduced interaction with floor wax is also provided.

02-18-2016

20090264536

Methods and composition for treating a material - A composition and method are described for sanitizing or otherwise treating a material such as a non-living surface, living tissue, soil or atmosphere which may be contaminated by a toxin, chemical warfare agent, insect, prion, microorganism or other infectious agent. Also described are methods of making the composition.

ANTIMICROBIAL ALCOHOL FOAM COMPOSITIONS AND METHODS OF PREPARATION - A method for preparing an antimicrobial alcoholic foam composition by combining two or more pre-mix compositions. A first pre-mix composition is primarily alcoholic comprises an alcohol, an acidic component, and a waxy component. A second pre-mix composition is primarily aqueous comprises water and a carbonate. An antimicrobial alcoholic foam composition that does not require added air or aerosol propellant is also provided.

03-19-2015

20130143970

MEDICINAL PREPARATION PARTICULARLY FOR THE TREATMENT OF SLIPPED DISCS HERNIAS - The invention concerns a product consisting in an injection medicinal formulations comprising at least one compound to provide a viscous formulation, ethanol and at least tungsten and/or tantalum metal making said formulation opaque to X rays so as to control its delivery and its action. Said formulation is in particular useful for treating herniated invertebral discs but also in intervention having demonstrated the efficacy of pure ethanol: treatment of hepatocellular tumours or osteoid osteomas, renal cysts and arterial-veinous angiomas.

06-06-2013

20130165528

DISINFECTANT DETERGENT COMPOSITION - A disinfectant detergent composition containing a food or food additive as a main component is provided. The disinfectant detergent composition contains the following components (a), (b), and (c). The sum [a+b] of the component (a) content and the component (b) content of the composition ranges from 0.1% to 30% by mass, the mass ratio [a/b] of the component (a) to the component (b) ranges from 1/2 to 4/1, and the component (c) content of the composition ranges from 60% to 99.5% by mass. (a) polyoxyethylene sorbitan monolaurate (b) a fatty acid glyceride in which the number of carbon atoms of its acyl group ranges from 8 to 12, the monoglyceride content of the component (b) being 85% by mass or more, the mass fraction of 1-monoglyceride relative to the total amount of monoglycerides being in the range of 0.9 to 1.0 (c) water and/or ethanol.

06-27-2013

20130274345

Antimicrobial Composition Having Skincare Properties - The invention relates to an antimicrobial composition which contains 80-95% by weight of ethanol 1-propanol, 2-propanol or the fixtures thereof. The hydroalcoholic composition according to the invention is preferably used, in hand disinfectants. Due to the oil components contained therein it is skin-friendly and has good skin care properties, thus making it possible to combine good disinfectant properties with good use properties and skin-friendliness.

10-17-2013

20130210929

TOPICAL GERMICIDAL COMPOSITIONS - Topical germicidal compositions for application to the epidermis comprise: 50-85% wt, of an alcohol constituent comprising one or more C

08-15-2013

20120184626

GERMICIDAL TOPICAL COMPOSITIONS - A topical germicidal composition comprising: 50-85% wt. of an alcohol constituent comprising one or more C1-C4 monohydric alcohols; 0.01-5% wt. of a film forming constituent based-on one or more celluloses or cellulose derivatives, 0.01-25% wt. of a humectant, preferably glycerine; 0.01-5% wt. of an opacifier constituent; optionally but preferably a Polyquaternium-type polymer or material; optionally one or more further constituents for improving the aesthetic or other technical characteristics of the invention, with the balance-of the composition, up to about 30% wt. of water, wherein the composition is characterized that it is flowable and preferably also exhibits an initial viscosity (“as mixed”) of at least about 10 cPs measured at 25° C., and subsequent to being stored at elevated temperatures and/or extended time intervals are retained as a single phase composition and do not split or separate into two or more phases, and further, the compositions provide a topical germicidal benefit when applied to the skin or parts of the body.

07-19-2012

20150297728

METHOD OF STABILIZING FOAM IN ALCOHOL-BASED HAND SANITIZERS USING DIMETHICONE POLYOLS AND ALKYLENE OXIDE POLYMERS AS ADJUVENTS - A method of stabilizing alcohol-based hand sanitizers comprising providing a first composition of matter that is a combination of a linear dimethicone copolyol, an alkylene oxide adjuvant selected from the group consisting of polyethylene oxide, and, polypropylene oxide, and, an alcohol, then, combining the first composition of matter with an alcohol-based hand sanitizer. A composition of matter comprising linear dimethicone copolyol, an alkylene oxide adjuvant selected from the group consisting of polyethylene oxide, and, polypropylene oxide, and, an alcohol, and, a further composition of matter comprising linear dimethicone copolyol, an alkylene oxide adjuvant selected from the group consisting of polyethylene oxide, and, polypropylene oxide, and, an alcohol combined with an alcohol-based hand sanitizer.

HYDROALCOHOLIC ANTIMICROBIAL COMPOSITION WITH SKIN HEALTH BENEFITS - The invention pertains to an alcohol based antimicrobial skincare composition. The invention also pertains to an alcohol based antimicrobial skincare composition with skin health benefits including moisturization and skin barrier maintenance effects. The invention further pertains to an alcohol based antimicrobial skincare composition that is a stable emulsion that has a certain viscosity to it that provides containment, for example on a user's hands. Finally, the invention pertains to an alcohol based antimicrobial skincare composition that may be used in the healthcare industry, for example as a surgical scrub, healthcare personnel handwash, or patient pre-operative site preparation.

CHEMICAL SYSTEM WITH SELF-TIMING INDICATOR - A pH-modified luminescent composition and methods. In composition, a marker exhibiting luminescence change over a indicatory period. pH-based luminesce change may be in intensity or in wavelength. One embodiment provides a luminescent composition, including a selected luminescent marker having a first phase; and a selected ionizing agent comprising a second phase. The selected luminescent marker exhibits luminescence for an indicatory period responsive to intermixing of the first phase with the second phase. A selected antimicrobial agent combined with the first phase of the luminescent composition, wherein intermixing of the first phase with the second phase is at least a portion of a hand hygiene protocol. A method embodiment of using the luminescent composition, can include providing a luminescent marker; providing a ionizing agent; intermixing the luminescent marker with the ionizing agent; causing a change in pH in the selected luminescent marker; and exhibiting luminescence for a predetermined indicatory period.

08-23-2012

20110105625

OPHTHALMIC COMPOSITION FOR CONTACT LENS - Disclosed are; a method for suppressing adsorption of a refreshing agent and/or chlorobutanol by a contact lens in an aqueous ophthalmic composition for contact lens containing a refreshing agent and/or chlorobutanol, as well as for suppressing pH decline due to degradation of chlorobutanol, wherein the method comprises preparing the composition in the form of an oil-in-water type emulsion. An ophthalmic composition for contact lens in the form of an oil-in-water type emulsion containing a refreshing agent and/or chlorobutanol is also disclosed.

05-05-2011

20120259019

COMPOSITION AND APPLICATION PROCESS FOR LIQUID ANTIFUNGAL - Embodiments of the present invention relate to a non-aqueous antifungal composition that comprises an alcoholic solvent, a preservative, a wetting agent and a flavoring agent, which can be used in the bakery industry when applied on the surface of products by spraying. Embodiments of the present invention result in food products having result reduced contamination by fungi and increased shelf life, without adversely affecting the product's flavor profile, texture and appearance.

10-11-2012

20110144214

HYDROALCOHOLIC GEL COMPOSITIONS FOR USE WITH DISPENSERS - A hydroalcoholic gel composition includes greater than about 40 weight percent of an alcohol, based upon the total weight of the alcoholic composition, a polyacrylate thickener, and an ester plug-preventing agent. The composition is suitable for use in dispensers, and exhibits reduced mis-directed output when the dispenser is actuated.

Extracts of Latex of Calotropis Procera and to a Method of Preparation Thereof - The invention relates to aqueous suspension of dried latex (DL) of Calotropis procera and to a method of preparation for the prevention/treatment of cancer. The DL suspension when administered orally in the X-myc mice—a transgenic mouse model of hepatocellular carcinoma (HCC), was effective in protecting the animals from the atypical mitosis and displastic/neoplastic changes occurring in vivo. Further, the DL suspension did not show any observable side effects when administered orally to the animals for 16 weeks. Further, the purified fractions of the latex were found to exhibit potent cytotoxic activity in in vitro cell culture system using two different cancer cell lines.

11-13-2008

20090082472

HAND SANITIZER AND METHOD OF PREPARATION - A sanitizing composition or hand gel composition having a blend of SDA and Isopropyl Alcohol to kill germs and bacteria, a thickener, such as an acrylic polymer, a stabilizer or polymer acrylic acid neutralizer, such as polyoxyethylene (15) coconut alkylamine, octyl isononanoate as an emollient, glycerin as an additional moisturizer, water, and optionally fragrance or other additives.

Skin Sanitizing Antimicrobial Alcoholic Compositions - This invention relates to an antimicrobial skin sanitizing composition for disinfecting skin, and particularly, hands. The composition contains at least 60 percent of an aliphatic alcohol having from 1 to 4 carbon atoms, from about 0.1 to about 5 weight percent of a thickening agent, and an effective amount of a GRAS or amino acid neutralizer to neutralize the thickening agent.

10-09-2008

20090018213

ANTIVIRAL METHOD - This invention provides a method of inactivating human noroviruses and other acid stable viruses. The method includes the step of contacting the virus with a virucidally-enhanced alcoholic composition that includes an alcohol, and an enhancer selected from cationic oligomers and polymers, chaotropic agents, and mixtures thereof.

01-15-2009

20080207767

Foamable Alcoholic Composition - A foamable composition includes greater than about 40 weight percent of an alcohol, based upon the total weight of the alcoholic composition, and a foaming surfactant selected from gemini surfactants, sulfuric acid esters, di-esters, C