Houghton was involved with England at U16 schools, U19, U20, U21 and U23 level. She was called into the full squad for a match against Germany on 25 October 2006, when Katie Chapman withdrew with an illness.[7] She was an unused substitute in the 5–1 defeat in Aalen.[8]

Houghton was called up to the first Great Britain women's side for the 2012 Summer Olympics as a defender. She became the team's record goalscorer from the left–back position, scoring in all three group games to help Great Britain to win the group with a 100% record, as well as making important challenges to help ensure the side progressed without conceding a goal. Houghton was also named left back of the tournament due to her outstanding performance during the games.[15]