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Not sure if this is exactly a solution, but usually these crashes are font issues.
You could try deactivating fonts in your Suitcase, or font manager, then opening the files. Quark has a hard time with font conflicts, and usually just crashes without letting you know that was the problem.

The file extension for your quark file is not being recognized as belonging to any any application installed on your computer or the file extension was lost when you transferred the file (in which case, you can rename the file and put the file extension back on, e.g. change MyFile to MyFile.qxp).

I'm assuming that you still have Quark installed on the computer you are trying to open the file on. If not, you should install it, which will resolve the problem.

You can try repairing an existing installation: Look in your control panel for programs installed on your computer. Click on the Quark installation to see if a change or repair option is shown for it. If so, attempt a repair, which may solve the problem.

I take it you mean it quits on startup, if so this is what I would suggest.

What you could
do is go to users folder then open up the folder of whoever is the active user (generally this user folder icon is a house icon) then open the library
folder then the preferences folder and then quark folder then QuarkXPress 6.0 folder.

In
this folder there is a file called "XPress Preferences.prf" move it to the
trash (Do not empty the trash if it does not work you can replace the
file back into the preference folder) and then start up Quark, it should
rebuild the file.

Please note your preferences will be back to
default and you will need to reset them.

I would also suggest that you go to www.quark.com then support and update your version of quark to the most up to date version from 6.0 possibly up to 6.1 or 6.52.

Try updating Quark first and reopen the document, if the problem persists, remove the preference file - this may have become corrupt.
Often a Quark crash is related to corrupt fonts, or fonts sharing the same id number as others already on the machine. Do you use a font manager such as Suitcase?

I had the same thing happen when I switched from os9 to osx. I had to install the programs, Quark, Illustrator, etc. then the icons appearance was normal. You may also have to actually open the program, then open the files themselves before the icons show as normal.