Gene Detail

Gene Symbol

SMYD3

Synonyms

bA74P14.1 | KMT3E | ZMYND1 | ZNFN3A1

Gene Description

SMYD3, SET and MYND domain containing 3, is a histone methyltransferase which regulates transcription through chromatin modification and as part of the RNA polymerase complex and therefore, plays a role in epigenetic gene regulation (PMID: 15235609; PMID: 28019723). Overexpression of Smyd3 has been linked to several types of cancer including breast, colorectal, and liver (PMID: 25382779; PMID: 28639750; PMID: 28123630).