Best Strong Drink (2004)

What do you get when you combine seventeen liquors with a smidgen of water? At Mario's Double Daughters, it's called Succo Vaffanculodi Mario, which translates roughly into English as "Mario's go-fuck-yourself juice." While the super-strong recipe is a well-guarded secret, the bright-red concoction is on display front and center in this whimsical LoDo bar, mocking weak stomachs as it gurgles in a glowing brass-and-steel tank riveted behind the long bar. If you're smart enough to pair the potent cocktail with a slice of greasy pizza from next-door sibling Two-Fisted Mario's, you might not black out after two glasses. But don't count on it.