The paper used a participatory and case study research approach to investigate the role of African Indigenous Food Security Strategies for climate change adaptation in Ganyesa Village, South Africa. The study revealed that local people, especially women, have over the years developed local food security strategies for climate change adaptation. These included knowledge of behaviours of living organisms, wind directions, position of stars as early warning indicators of changing weather conditions, selection of appropriate seeds and animal species, mixed cropping, and water harvesting technologies and food preservation techniques such as fermentation and sun drying for food security. These knowledge systems tend to be marginalized in the search for sustainable solutions for food security and climate change. The study recommends their documentation to inform policy, incorporation into educational curriculum. This will also assist in identifying gaps to be improved through interface with other knowledge systems.