Cutting-edge Issues in Autoimmunity and Allergy of the Digestive System

Clinical Reviews in Allergy and Immunology, 05/17/2012

Selmi C – Autoimmunity and allergy involving the digestive system may be considered as paradigmatic for numerous common themes of complex diseases secondary to tolerance breakdown.Similarly, it is intriguing that the gastrointestinal tract and the liver circulation represent the crucial environment for the development of immune tolerance. This issue is dedicated to the discussion of recent concepts while identifying two major common issues, i.e., the need for serum biomarkers and the role of vitamin D.