A safe data can be insecure, if the data is monitored but not tampered during transit
A secure data can be unsafe, if the data is not tampered during transit but has got corrupted due to physical or electronic medium

Local storage

A safe data can be insecure, if the data is stored without corruption but data is visible to third party
A secure data can be unsafe, if the data has username or password to access but hard drive is corrupt

Cloud storage

A safe data can be in secure, if the data is stored as it was transferred but the data was compromised during transmission by network bots or network protocol snooping
A secure data can be unsafe, if the data transferred gets corrupted and no checksums or data consistency checking is available

Computing

A safe data can be insecure, if the data structure is consistent with user data but a Trojan program is using the same data through some access maliciously within the computing unit
A secure data can be unsafe, if the data structure has a data that has been computed incorrectly by the user program and updated due to a bug in the system