Background: Diabetes and hypertension is affecting at an alarming rate in both rural and urban populations in India and very few studies had been carried out among the tribal population. Objective: To determine the prevalence rate of type 2 diabetes mellitus and hypertension and its associated risk factors among the tribal population in Salem District in Tamil Nadu. Materials and Methods: A total of about 525 tribal population above 40 years of age from various tribal places in Yercaud. All of them were screened for diabetes, by checking the random blood glucose levels and blood pressure, body mass index, dietary patterns, and physical activity levels were also recorded. Their knowledge about diabetes was also assessed by a set of 10 questions. Results: Among the study population, people who had RBS ΃ 200 was 28 (male = 11 and female = 17) and between 140 and 200 were 39 (male = 18 and female = 21) and people whose were in the prehypertensive stage was 185 (males 92 and female 93) and people in the stage 1 hypertension was 102 (male = 47 and female = 54) and in stage 2 hypertension was 64 (male = 33 and female = 29). The co-morbidity (diabetes and hypertension) was present in among 45 (male = 25 and female = 20). Among the study population only 1 was obese and 39 were overweight. Among the various risk factors smoking, alcohol and positive family history were found to have a statistical significant association for males whereas among females only the family history was found to have a statistically significant association for both diabetes and hypertension. The knowledge of diabetes among the study population was very poor. None of them were aware about the normal levels of blood sugar and the risk factors. Conclusion: The study documented that the prevalence of diabetes and hypertension is increasingly high in the tribal areas and their awareness levels were very poor.