enantiomer

enantiomer,

another term for optical isomer. See Stereoisomers under isomerisomer, in chemistry, one of two or more compounds having the same molecular formula but different structures (arrangements of atoms in the molecule). Isomerism is the occurrence of such compounds. Isomerism was first recognized by J. J. Berzelius in 1827......Click the link for more information..

127) However, in response to several cases where negative side effects were attributed to the undesired enantiomer, (128) the FDA now requires data pertaining to the individual enantiomers of a chiral drug.

Moreover, he found that a PHOSITA had no way of knowing what the properties of the d-enantiomer and its salts would be without testing the individual combinations; therefore, the beneficial properties of clopidogrel were not known before the racemic mixture was separated into its enantiomers.

Determining the handedness of a given molecule is of utmost importance in chiral studies, and VCD is a technique for determining this characteristic that does not require the addition of foreign samples or the separation of enantiomers.

Chiral separation chromatography is a technique involving two enantiomers of the same compound with different affinities for the stationary phase consisting of a single enantiomer, thus possessing different elution times.

This was an unanticipated result, since it is not very common to find the opposite enantiomers (left- and right-handed forms) of the same compound among the secondary metabolites of related species," he added.

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