Losing on the road to San Diego in Week 2 was explainable: Great QB in Philip Rivers with stellar receiving corps, weather above 100 degrees, very hostile crowd. But losing to the Dallas Cowboys in the supposedly unbeatable Seattle stadium? That was a real head-scratcher. Either the Seahawks just got outright beaten by a very good football team (likely) or maybe the Seahawks have more weaknesses on offense than many of their staunchest supporters care to admit.

Whatever the case may be, the Seahawks are 4-2, a half-game out of first place behind the Arizona Cardinals (who will likely get a very easy win over the Oakland Raiders next Sunday) and now have to go on the road to face a surprisingly resilient St. Louis Rams team.

Here are the 5 biggest losers from Week 6 of the NFL season:

Buffalo Bills – The Bills coaching staff had a chance to impress new owner Terry Pegula with an AFC East division lead on the line, but the Bills squandered the opportunity, rarely utilizing RB C.J. Spiller and getting blown out by the New England Patriots.

The Winless Teams (Oakland Raiders and Jacksonville Jaguars) – Oakland and Jacksonville each had huge opportunities – Oakland managed to score 4 TDs in a shootout with the San Diego Chargers, and the Jaguars were only one score away from their first win of the year against Tennessee. Ultimately the lack of talent on their teams cost them to miss big opportunities to get that first Win – and by a total margin of only 5 points.

Tampa Bay Buccaneers – If not for the win against Pittsburgh this Buccaneers team would easily be considered the worst team in football. They have been outscored in just the two losses to the Atlanta Falcons and the Baltimore Ravens by a combined 104-31 – and this is coming on the watch of head coach Lovie Smith, a defensive mastermind.

New York Giants – Hard to tell which is more painful to think about, the fact that Victor Cruz dropped the Giants only decent Redzone pass in the game, or the fact that he tore his patellar tendon and has to go on injured reserve as a result of the play?

Seattle Seahawks – With two losses in their first 6 games, there are now 6 teams ahead of the Seahawks in the running for home-field advantage throughout the playoffs, which the ‘Hawks will most likely need in order to go back to the Superbowl.