A Middleweight Championship bout between Anderson Silva and Vitor Belfort was confirmed by UFC President Dana White,[5] although it was contingent on Silva's successful recovery from elbow surgery.[6] Subsequently, the fight was rescheduled due to Silva's continued slow healing from surgery.[7] The Silva vs. Belfort bout was expected to take place at UFC 112, however Belfort was forced to withdraw from the fight and Demian Maia replaced him, after number one contender Chael Sonnen was not clear to fight.[8]

The bout between Randy Couture and Mark Coleman was originally scheduled for UFC 17 in 1998, but a Couture injury forced the cancellation of the bout. Nearly twelve years later, this bout headlined UFC 109. It marked the first time in UFC history that two Hall of Fame inductees fought in an event.[11]

The following is the reported payout to the fighters as reported to the Nevada State Athletic Commission. It does not include sponsor money or "locker room" bonuses often given by the UFC and also do not include the UFC's traditional "fight night" bonuses.[18]