Pre_GI: SWBIT SVG BLASTP

Query: NC_010162:573709 Sorangium cellulosum 'So ce 56', complete genomeLineage: Sorangium cellulosum; Sorangium; Polyangiaceae; Myxococcales; Proteobacteria; BacteriaGeneral Information: Sorangium cellulosum 'So ce 56' produces a large number of bioactive compounds, such as, the antifungal soraphen and the anticancer agent epothilone. This organism, like other myxobacteria, undergoes a complex development and differentiation pathway. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100 000 cells. The motility system is not dependent on flagella like most bacteria, but instead relies on twitching pili: short extracellular appendages that may function analogously to oars in a rowboat. The myxobacteria have proved to be a rich source of novel natural products. Sorangium cellulosum produces a number of antibacterial, antifungal and cytotoxic substances which are being studies for therapeutic applications.

General Information: Thermophillic halophile. Halothermothrix orenii H 168 was isolated from the sediment of a salt lake in Tunisia. This organism is a member of a group of anaerobic halophilic bacteria related to the Clostridia. This organism is a thermophile and therefore is able to grow in hot anaerobic saline environments.