After witnessing a violent shakedown, Carmen and Wayne Colson (Diane Lane and Thomas Jane) are ushered under the arm of the Federal Witness Protection program, where they're supposed to be well taken care of. But with an experienced hit man (Mickey Rourke) and a rookie killer (Joseph Gordon-Levitt) on their heels, hiding out will be more difficult than they thought. Rosario Dawson and "Jackass" Johnny Knoxville co-star.