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Aside from synthetic chemistry services, Sai can offer a fully integrated drug discovery service. Medicinal chemists work closely with the Computational Chemistry, Biology, DMPK, Process development and formulation departments thereby exemplifying the skills together to develop a lead candidate.

Sai emphasizes training, coaching and mentorship which results in an excellent retention rate for our scientists.

Synthetic and Medicinal Chemistry Services offered by Sai include:

Design and synthesis of analogues to support lead generation and optimization

Representative types of chemistries handled thus far with success:

Sai’s Chemistry Services Team

At Sai, we ensure that each of the teams supporting the client’s medicinal chemistry is led by a Project Team Leader with either extensive discovery experience in a US/EU biopharma company or with a track record of success in delivering compounds within a CRO context.

Sai’s Library Design and Synthesis Team

Sai has a dedicated library synthesis team to deliver targeted arrays of drug-like compounds. This expert team is versed in deploying various state-of the-art instruments and techniques and routinely delivers chemical libraries ranging in size from 50 to 200 compounds with varying degrees of synthetic and structural complexity. Our Medicinal chemistry teams closely work with Computational chemistry team during the library design and enumeration process.

Sai’s MedChem Analytical Capabilities

Sai Life Sciences offers a state of the art Analytical R&D to fulfill all your analytical and purification requirements. Our highly talented workforce is led by group leaders with vast experience in Contract research / Discovery sciences industries.

Our strengths include method development for the isolation and structure elucidation of chiral and achiral compounds and also their complete characterization; equipped with a range of column chemistries such as C18 – HILIC – DIOL supported by sophisticated equipment such as SFC, mass directed prep HPLC machine and two 400MHz NMR instruments.

Regular calibration & authorized service facilitates significant reducing down-time of the equipment. We have also implemented protocols designed for early detection of purity and integrity issues of compounds.