Today’s world of increasing interconnectivity and mobility accelerates the shared global risk to human health and well-being; a pathogen from a remote village can reach major cities on all continents within 36 hours. To address this threat, CDC brings unique technical expertise, capabilities, and decades of experience to its role in protecting people from global infectious diseases. Captain Nancy Knight, who leads the CDC’s Division of Global Health Protection and spent a decade overseas with CDC, will provide an overview of how the agency works directly with other countries to address vulnerabilities in their ability to prevent, detect, and respond to outbreaks. Using country case studies and data, she will illustrate the progress made in health security over the last few years, as well as the gaps that remain. From the economic impact of pandemics to the national security implications of lax biosafety, she will offer a unique perspective on the ways in which CDC helps protect the health, safety, and security of people around the world.