Medications for Urinary Tract Infection (UTI)

The information provided here is meant to give you a general idea about each of the medications listed below. Only the most general side effects are included, so ask your doctor if you need to take any special precautions. Only use each of these medications as recommended by your doctor, or according to the instructions provided. If you have further questions about usage or side effects, contact your doctor.

You may be prescribed antibiotics for 3 or more days. A 3-day course has been shown to be helpful for both younger and older women with
urinary tract infections
(UTIs), rather than taking the medication for up to 10 days or more. You should take the full course of medication, even if you begin to feel better before all the medication is gone.

In some cases, severe UTIs are treated with IV or intramuscular antibiotics. Researchers, though, have found that oral antibiotics appear to be as effective in treating UTIs as those given as injections.

If you are suspected of having a more serious infection, such as a
kidney infection, you may need hospitalization, IV antibiotics, and fluids.

May interfere with oral contraceptive pills—Use another form of contraception while you are taking these antibiotics.

May interfere with sugar levels in people with diabetes—Check with your doctor before you change your dose of insulin or other diabetes drugs.

Note:
Some antibiotics should not be taken with alcohol. Check with your doctor.

Fluoroquinolone Antibiotics

Common names include:

Ciprofloxacin

Levofloxacin

Norfloxacin

Ofloxacin

If you are taking antacids or sucralfate, do not take them within 6 hours of taking a fluoroquinolone.
Take with a full glass of water. Take norfloxacin on an empty stomach. The other medications may be taken either on an empty stomach or with meals.

Possible side effects include:

May interact with antacids or sucralfate—Do not take these medications within 2-6 hours of each other.

Increased sensitivity to sun

Lightheadedness—Do not drive or participate in potentially hazardous activities until you know how these medications will affect you.

Inflamed, torn tendons

Low blood sugar in people with diabetes

Irregular heartbeat if you have low potassium in your blood

For levofloxacin—Check with doctor before taking this drug if you are taking medications for your heartbeat.

For enoxacin—Check with your doctor before taking this drug along with caffeinated products.

Trimethoprim-sulfamethoxazole
Antibiotic

Common brand names include:

Bactrim

Cotrim

Septra

Trimethoprim-sulfamethoxazole
is usually not prescribed for babies less than three months of age. Older people have an increased risk of skin and bleeding problems with these medications, especially if they are already using diuretic medications. Always take these drugs with a full glass of water.

Lightheadedness—Do not drive or participate in potentially hazardous activities until you know how these medications will affect you.

Nitrofurantoin Antibiotics

Common brand names include:

Furadantin

Macrodantin

Take nitrofurantoin
with food or milk in order to decrease the chance of stomach upset.
Possible side effects include:

May interfere with sugar levels in people with diabetes—Check with your doctor before you change your dose of insulin or other diabetes drugs.

Diarrhea

Intestinal gas

Medications for Symptom Relief

Phenazopyridine

Common brand names include:

Basidium

Erodium

AZO Standard

Pyridium

Phenazopyridine
can help relieve the burning, urgency, and frequency of a UTI. You should stop taking it when you are no longer having discomfort. It is usually advised not to take this medication for longer than 2 days. Take with food to decrease the chance of stomach upset. Do not wear soft contact lenses while you are using this drug as it may permanently stain the lenses.

Possible side effects include:

Reddish-orange color to your urine and sweat

Headache

Stomach irritation

Call your doctor immediately if you are taking this drug and notice:

Shortness of breath

Confusion

Decreased urine

Blue color to your skin

Combination Medications

Common brand names include:

Prosed

Urised

Prosed and Urised contain a combination of drugs to treat an infection, reduce bladder spasm, and relieve pain. These medications should always be taken with a full glass of water.

Possible side effects include:

Lightheadedness, sleepiness, blurred vision, changes in thinking—Do not drive or do hazardous activities until you know how these medications will affect you.

Nausea or vomiting

Dry mouth

Change in color of urine or stool to blue or green

Call your doctor right away if you are taking this drug and have:

Difficulty breathing

Severe lightheadedness

Severe diarrhea

Significant change in thinking clearly and logically

Unable to pass urine

Fast heartbeat

Sudden change in vision

Rash

Older people may have more side effects when taking Prosed or Urised.

Special Considerations

If you are taking medications, follow these general guidelines:

Take the medication as directed. Do not change the amount or the schedule.

Ask what side effects could occur. Report them to your doctor.

Talk to your doctor before you stop taking any prescription medication.

Plan ahead for refills if you need them.

Do not share your prescription medication with anyone.

Drugs can be dangerous when mixed. Talk to your doctor if you are taking more than one drug, including over-the-counter products and supplements.

Revision Information

This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.