More heart drugs recalled due to presence of cancer-causing impurity

Two lots of Torrent Pharmaceuticals Limited’s Losartan potassium tablets are the latest heart drugs to be recalled due to the presence of a probable human carcinogen called N-nitrosodiethylamine (NDEA).

Losartan is used to treat hypertension, hypertensive patients with left ventricular hypertrophy and for the treatment of nephropathy in type 2 diabetic patients. Patients currently taking Losartan should continue taking the medication because the risk of harm may be greater if the treatment is stopped abruptly without an alternative medication. Patients should contact their pharmacist or physician with concerns.

Lorsartan is in a class of drugs called angiotensin II receptor blockers, or ARBs, which are used to treat high blood pressure and heart failure. In July, the Food and Drug Administration announced a recall of another ARB, Valsartan, due to the presence of NDEA. Since then, several ARBs – including Valsartan, Lorsartan and Irbesartan – have been recalled due to the presence of NDEA. The FDA has an ongoing investigation into ARBs and whether they contain carcinogenic impurities.

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