The US Food and Drug Administration (FDA) has taken the unusual step
of asking its parent agency, the Department of Health and Human Services,
to investigate one of its own clinical trials for lapses in patient record
handling (http://www.fda.gov/oc/mcclellan/navalacademy.html).

According to an FDA statement, 92 of 260 patient files were missing
in the study of a dietary strategy to maximize bone mass in US Naval Academy
students. The FDA also asked for an investigation into the study's "financial
integrity."