The effects are a subtle calm and mood lifting improved sleep. Took me a few weeks to notice them. I am getting one side effect that I get on SSRI's so this leads me to believe this product acts on serotonin. Need more time to evaluate further.

This brand of Sam-E seems about as effective as most of the other brands for a lower cost. I am able to sprint run for the first time in at least a decade. I can also jog quite far which was almost impossible. I have been taking 2 tablets a day. I feel a big difference on days that I forget to take it. It also gives me More energy, alertness, motivation.