Abstract

We demonstrate three-dimensional (3D) self-assemblegrowth of the metallothionein (Mn,Cd-MT-2) molecules on patterned semiconductor substrates. The MT molecules deposited on the patterned substrates were found to grow into 3D rod or ring-type nanostructures, depending on the shape of patternednanostructures on the substrates. Dense arrays of 3D molecular nanorods or rings with an area density close to were demonstrated with a pore size of and a pitch size of . Those engineered molecular nanostructures provide an excellent opportunity for biological applications, sensing sources of nanodevices, biochemical reactions on surfaces, and even single molecule studies.