Institute of Biochemistry and Molecular Medicine, University of Bern, Switzerland

Beta-Caryophyllene (BCP) Research

projects - preclinical studies

Beta-Caryophyllene Molecular Mechanisms / Pharmacology

The widespread plant sesquiterpene contains a quite rare cyclobutane ring which is essential for the conformation of this molecule. Beta-caryophyllene is a bioavailable apparently non-toxic and potent CB2 receptor agonist (in vivo) which shows an array of protective and therapeutic effects in preclinical studies. Given the abundance of CB2 receptors in distinct disease tissues, the therapeutic potential is broad. Here we collect all publications which show quality animal studies and/or mechanistic research.