daily dose of an investigational medication has been found to restore muscle mass in the arms and legs of older adults and improve some of their biochemistry to levels found in healthy young adults, suggesting an anti-frailty drug has been found.

The drug, called MK-677, was evaluated for its safety and effectiveness in a study that showed the drug restored 20 percent of muscle mass loss associated with normal aging. In fact, levels of growth hormone (GH) and of insulin-like growth factor I (IGF- I) in healthy seniors who took the drug increased to the levels found in healthy young adults, said Michael O. Thorner, a professor of internal medicine and neurosurgery at the University of Virginia Health System