intramembranous ossification ossification of bone that occurs in and replaces connective tissue.

metaplastic ossification the development of bony substance in normally soft body structures; called also heterotrophic ossification.

os·si·fi·ca·tion

(os'i-fi-kā'shŭn),

1. The formation of bone.

2. A change into bone.

[L. ossificatio, fr. os, bone, + facio, to make]

ossification

/os·si·fi·ca·tion/ (os″ĭ-fĭ-ka´shun) formation of or conversion into bone or a bony substance.

ectopic ossification a pathological condition in which bone arises in tissues not in the osseous system and in connective tissues usually not manifesting osteogenic properties.

endochondral ossification ossification that occurs in and replaces cartilage.

heterotopic ossification the formation of bone in abnormal locations, secondary to pathology.

intramembranous ossification ossification that occurs in and replaces connective tissue.

ossification

(ŏs′ə-fĭ-kā′shən)

n.

1. The natural process of bone formation.

2.

a. The hardening or calcification of soft tissue into a bonelike material.

b. A mass or deposit of such material.

3.

a. The process of becoming set in a rigidly conventional pattern, as of behavior, habits, or beliefs.

b. Rigid, unimaginative convention.

ossification

[os′ifikā′shən]

Etymology: L, os + facere, to make

the development of bone. Intramembranous ossification is that preceded by membrane, such as in the process initially forming the roof and sides of the skull. Intracartilaginous endochondral ossification is that preceded by rods of cartilage, such as that forming the bones of the limbs.

Ossification

os·si·fi·ca·tion

(os'i-fi-kā'shŭn)

1. The formation of bone.

2. A change into bone.

[L. ossificatio, fr. os, bone, + facio, to make]

ossification

(os?i-fi-ka'shun) [? + facere, to make]

1. The formation of bone matrix.

2. The replacement of other tissue by bone, esp. during fetal development. See: osteogenesis

ENDOCHONDRAL OSSIFICATION: Ossification process in a long bone; (A) progression from embryo to young adult, (B) microscopic view of an epiphyseal disk

ENDOCHONDRAL OSSIFICATION

endochondral ossification

The formation of bone in cartilage, as in the formation of long bones, involving the destruction and removal of cartilage and the formation of osseous tissue in the space formerly occupied by the cartilage. See: illustration

illustration

intramembranous ossification

The formation of bone in or underneath a fibrous membrane, such as occurs in the formation of the cranial bones.

pathologic ossification

The formation of bone in abnormal sites or abnormal development of bone.

periosteal ossification

The formation of successive thin layers of bone by osteoblasts between the underlying bone or cartilage and the cellular and fibrous layer that covers the forming bone. Also called subperiosteal ossification.

ossification

The process of conversion of other tissues into bone. Most bone forms from CARTILAGE but some is laid down by other connective tissue (membranous bone). Ossification may also occur in tissues that have been the site of disease such as long-term inflammation.

ossification

causes a progressive lameness of the shoulder joint of the horse. The calcification of the tendon can be identified radiologically.

ossification center

a locus in an epiphysis or other part of a bone at which ossification commences and from which it spreads over the entire section. Radiological examination can detect the appearance of each ossification center and this is of assistance in aging.

dural ossification

occurs in large and giant breed dogs. Detected radiographically, most commonly in the lumbar and cranial and caudal cervical areas, but rarely produces clinical signs. Called also ossifying pachymeningitis.

the ossification of cartilage in growing large dogs may be retarded and, at the distal ulnar growth plate, resembles premature closure of the plate; the characteristic lesion is a cone of uncalcified cartilage in the growth plate.

Patient discussion about ossification

Q. is their any way to cure osteogenesis imperfecta my son has this bone disorder and can;t stand to see him cry thank you for any help

A. as far as i know- OI is a genetic problem. today there is no cure to genetic problems. there is a big research on gene therapy but there's a long long road before we will see any result..sorry... but there are several treatments that can ease your son's pain, here is a wonderful site that stores a vast amount of information about IO, including recent studies and researches:http://www.oif.org/site/PageServer

4) Enthesopathy adjacent to peripheral joints is common, and sites, such as the distal clavicle, greater and lesser tubercles, pelvis, tibial spine, heel, patella, and olecranon, have been identified as locations of increased calcification and ossification in DISH.

During embryonic development, ossification begins at the 5th week with the appearance of two primary centres of ossification, a medial and a lateral centre in the shaft of the clavicle, which fuse at about the 6th week [10-11].

The design rationale of the Struxxure ACP system is based on published papers highlighting studies reporting the incidence of adjacent level ossification significantly decreases when the plate-to-disc distance is greater than 5millimeters from the adjacent level.

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