Using a new generation of polymers to wage war on hospital bacteria

A team of researchers from the Faculty of Science and Technology of the University of Coimbra (FCTUC) in Portugal, has developed a new generation of polymers (macromolecules) with antimicrobial properties that could prove crucial in the fight against bacteria in hospitals.

The research was led by Jorge Coelho and Paula Morais, who explained that: “After a series of experiments carried out in the laboratory, the new polymers showed a high rate of activity against a wide range of bacteria strains. This is indicative of activity against pathogenic bacteria and data showed the bacteria were exterminated when placed in contact with the polymers."

Coelho and Morais emphasised that: "By manipulating the structure of the polymer, it is possible to guarantee an effective performance against a broad spectrum of bacteria, in a completely safe way".

Considering the problem of antibiotic resistance, this research is of particular relevance because it demonstrates that bacteria can be eliminated before transmission occurs. With a large majority of infections occurring in the hospital environment, it is essential to investigate innovative ways to prevent and combat them.

The new polymers were developed as part of a project whose final objective was the invention of an antibacterial coating (a type of varnish) for application in health units. The production method tested in the laboratory can be ramped up on an industrial scale, thus facilitating its introduction into the market.

The study was funded by the Foundation for Science and Technology (FCT) and has the collaboration of the Faculty of Engineering of Porto (FEUP). The results were published in the scientific journal Biomacromolecules.

If all goes as planned, the researchers estimate that the new antimicrobial coating can enter the commercial circuit in two to three years.