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PHYSICAL THERAPY IMPLICATIONS

Examination and Evaluation

Monitor and report immediately signs of neuroleptic malignant syndrome, including hyperthermia, diaphoresis, generalized muscle rigidity, altered mental status, tachycardia, changes in blood pressure (BP), and incontinence. Symptoms typically occur within 4–14 days after initiation of drug therapy, but can occur at any time during drug use.

Watch for signs of agranulocytosis and leukopenia, including fever, sore throat, mucosal lesions, and
other signs of infection. Report these signs to the physician or nursing staff immediately.

Assess motor function, and be alert for extrapyramidal symptoms. Report these symptoms immediately, especially tardive dyskinesia, because this problem may be irreversible. Common extrapyramidal symptoms include: