The closest would be System Safety Monitor which works (but with reduced functionality) on Win9x/ME. The issue here is that Windows NT/2K/XP has a split between "privileged" kernel mode (which Process Guard uses) and user mode programs - Windows 9x/ME lack this so do cannot offer the features Process Guard needs. Abtrusion Protector, PrevX and Safe'n'Secure also require Windows 2000/XP.

SSM prompts on application activity (including running programs, process injection, driver installation and low-level activity) so it is more suited to technical users.