Medicine Man: At 1st level, a pharmakon gains the Life sphere and Affliction talent as a bonus talents, as well as the Limited Restoration (restore only) drawback. This drawback does not grant an additional talent and may be bought off as normal. If the pharmakon already possesses the Life sphere, then the Affliction talent is gained as a bonus talent with no drawback. If both are already possessed, then she may choose any talent from the Life sphere as a bonus talent. When using the Affliction talent, the pharmakon may spend uses of channel energy in place of spell points.

Iatrogen At 2nd level, and every 4 additional levels thereafter (6th, 10th, 14th, etc.), the pharmakon gains an iatrogen of her choice. An iatrogen is an effect similar to a useage of the Affliction talent, but is much more potent and powerful.

Each iatrogen can only be powered by spending uses of channel energy in place of spell points, including when combined with talents that allow the affecting of multiple creatures.

Whenever a iatrogen calls for a saving throw, the DC is equal to 10 + 1/2 her class level + her casting ability modifier. If the pharmakon uses any iatrogen on a creature who is already under the effect of 3 or more different iatrogenic effects, the target must make a Fortitude save or drop to -1 hit points and dying.

Exsanguination: The pharmakon can use the Affliction talent to inflict 1d6 bleed damage, plus an additional 1d6 bleed damage per Greater Healing talent she possesses.

Malignance: The pharmakon inflicts a 1d6 ability penalty to a single ability score of her choice. If the pharmakon has the Greater Restore talent, she instead inflicts this ability penalty to all ability scores. This ability penalty lasts a number of rounds equal to his class level (Fortitude negates). Ability penalties from malignance does not stack with itself.

Neurasthenia: The pharmakon inflicts the frightened (or panicked, if already frightened) condition for a number of rounds equal to his pharmakon level (Will negates). This is a mind affecting fear effect.

Opisthotonus: The pharmakon inflicts the staggered condition for a number of rounds equal to his class level (Fort negates). If the target is already under the effect of the staggered condition, it is instead paralyzed for a single round.

Polysynapsis: The pharmakon grants a target twice the temporary hit points she can normally grant via the invigorate Life sphere ability. These temporary hit points can bring a target’s current hit points above their total hit points. However, when the duration expires (the pharmakon may end the duration prematurely as a free action), the creature loses hit points equal to the number of temporary hit points granted.

Sepsis: The pharmakon inflicts a disease onto the target, as per the Inflict Disease talent from the Death sphere.

Syncope: The pharmakon inflicts temporary negative levels onto the target, as per the Drain talent from the Death sphere.