SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a ’tag peptide’, a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (159 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

Noca_2017

Noca_3105

Noca_2017

Noca_3105

Ribonuclease II

Alpha/beta hydrolase fold protein

0.408

Noca_2017

smpB

Noca_2017

Noca_1272

Ribonuclease II

SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a ’tag peptide’, a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]

0.549

Noca_3102

Noca_3103

Noca_3102

Noca_3103

Hypothetical protein

Flavin reductase domain-containing protein

0.845

Noca_3102

Noca_3104

Noca_3102

Noca_3104

Hypothetical protein

Phospholipid/glycerol acyltransferase

0.845

Noca_3102

Noca_3105

Noca_3102

Noca_3105

Hypothetical protein

Alpha/beta hydrolase fold protein

0.622

Noca_3102

Noca_3106

Noca_3102

Noca_3106

Hypothetical protein

Hypothetical protein

0.592

Noca_3102

Noca_3107

Noca_3102

Noca_3107

Hypothetical protein

LOR/SDH bifunctional protein

0.477

Noca_3103

Noca_3102

Noca_3103

Noca_3102

Flavin reductase domain-containing protein

Hypothetical protein

0.845

Noca_3103

Noca_3104

Noca_3103

Noca_3104

Flavin reductase domain-containing protein

Phospholipid/glycerol acyltransferase

0.859

Noca_3103

Noca_3105

Noca_3103

Noca_3105

Flavin reductase domain-containing protein

Alpha/beta hydrolase fold protein

0.631

Noca_3103

Noca_3106

Noca_3103

Noca_3106

Flavin reductase domain-containing protein

Hypothetical protein

0.601

Noca_3103

Noca_3107

Noca_3103

Noca_3107

Flavin reductase domain-containing protein

LOR/SDH bifunctional protein

0.483

Noca_3104

Noca_3102

Noca_3104

Noca_3102

Phospholipid/glycerol acyltransferase

Hypothetical protein

0.845

Noca_3104

Noca_3103

Noca_3104

Noca_3103

Phospholipid/glycerol acyltransferase

Flavin reductase domain-containing protein

0.859

Noca_3104

Noca_3105

Noca_3104

Noca_3105

Phospholipid/glycerol acyltransferase

Alpha/beta hydrolase fold protein

0.755

Noca_3104

Noca_3106

Noca_3104

Noca_3106

Phospholipid/glycerol acyltransferase

Hypothetical protein

0.601

Noca_3104

Noca_3107

Noca_3104

Noca_3107

Phospholipid/glycerol acyltransferase

LOR/SDH bifunctional protein

0.483

Noca_3105

Noca_2017

Noca_3105

Noca_2017

Alpha/beta hydrolase fold protein

Ribonuclease II

0.408

Noca_3105

Noca_3102

Noca_3105

Noca_3102

Alpha/beta hydrolase fold protein

Hypothetical protein

0.622

Noca_3105

Noca_3103

Noca_3105

Noca_3103

Alpha/beta hydrolase fold protein

Flavin reductase domain-containing protein

0.631

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Network Stats

Network Stats analysis is still ongoing, please wait ...

Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: