Is this the printer that has four individual cartridges side by side? If so, I believe it says "push" on the top of the cartridge. When you do, the securing apparatus will pop up, allowing you to remove the cartridge. Simply tilt the cartridge toward you. It will "snap" out of its seat. You snap the new one in that same place after removing the plastic seal from it. Press the securing apparatus back down, and you're good to go!

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Removing/loading the cartridge are not related to powering section, check adapter voltage if its ok observe any spark generating while inserting the adapter pin in the printer socket if yes there is short in logic card, replace the logic(formatter) card..* very very rare cases if cartridge got short it will damage the logic card,result printer goes in dead condition.

Usually this problem is indicative of a clogged nozzle. I'm not sure about the track record of the Photosmart C5280 (a lot of Epson printers have this problem, and you just have to keep replacing the ink cartridges). I'm going to assume you tried this, but go ahead and run a few cleaning cycles on the printer, and see what happens.