47750 - Rat RotaRod NG

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The “Rota-Rod” technique is essential in screening drugs potentially active, or having side effects, on motor coordination. Ugo Basile designed the original RotaRod, the first industrial Rota Rod almost 50 years ago, based on the 1957 paper by N.W Dunham and T.S Miya. The 47750 RotaRod NG (Next Generation), is an evolution of the original model and the result of many years of research in cooperation with the latest development in behavioral and pharmacological research.

Since then, our models have been cited in thousands of scientific papers. The name we coined soon became so popular, now everybody knows this devuce as RotaRod!

What's new in the NG model:

Physically similar to the previous versions, it offers the same reliability, matched with innovative technology! The new model features stainless-steel trip-boxes to facilitate cleaning and confine the animals when they fall off the rod.

The Rat RotaRod consists of four 6cm diam. cylinders, which are suitably machined to provide grip. Five 49cm diam. dividers make for four lanes, each 8.7cm wide, enabling four rats to be on the rotor simultaneously. The height to fall is 30cm.

A brand new, user friendly software, is included as standard; via the new software, the operator can easily organize the experiment on her/his PC, and upload it to the Rota-Rod via the USB key. The software automatically classifies the data, combining configuration settings with test results; the user can add information, before or after the test. Results appear in a tree-like structure, where columns can be dragged and dropped to customize the layout. Configurations and data are exported as Text, Excel or Pdf reports and can be saved to cloud via DropBox, OneDrive, GoogleDrive.

The experiment can be set and results can be monitored, also via the 4”3 touch-screen.

Remote diagnosis and internet access are provided.

The 47750 combines the same functionality of the previous version, now considered the standard, with additional new features: surprisingly silent operation, much easier experimental organization and data management.

NEXT GENERATION ROTAROD: SAME RELIABILITY, INNOVATIVE TECHNOLOGY!

FEATURE

BENEFIT

Speed adjustable in the range

5-80 RPM, in steps of 1 RPM

Useful in a variety of tests

Constant speed, ramp (accelerat­ing), multi-step ramp (NEW!)

Extreme versatility

New trip boxes

To enclose the animals, stainless-steel to ease sterilization

Embedded USB memory stick

Does not required connection to PC (software included) to store and transfer data

Brand new Software

user friendly, included as stan­dard, enables setting up the experiment and managing the results from PC or 4"3 touch-screen

General

Commands

4”3 touch-screen (resistive)

Read-out

on the touch-screen

Power Requirement

Universal input 85-264 VAC, 50-60Hz, 40W max.

Sound Level

< 60 dB (A)

Operating Temperature

10° to 40° C

Operation

Speed

adjustable in the range 5-80 RPM, in steps of 1 RPM

Mode

constant, ramp (accelerating), multi-step ramp (NEW!)

Rotation

forward, reverse, rocking

Rotor Start/Stop

on the touch-screen

Counting Start /Stop

each section via its trip box

Trip-Box

stainless-steel to ease sterilization

Drive

forward, reverse, rocking

Data Acquisition

via X-PAD software, provided

Data Portability

by USB flash drive

TTL Output

for lane status, rotation and speed

Data

exported to Text, Excel or Pdf, or saved to cloud to DropBox, OneDrive, GoogleDrive

Configurations

exported to Text, Excel or Pdf, or saved to cloud to DropBox, OneDrive, GoogleDrive

Physical

Total Weight

15Kg

Shipping Weight

21Kg approx.

Dimensions

55(w)x46(d)x57(h)cm

Packing Dimensions

76x60x80cm

Warranty

47750 is covered by a 24-month warranty

The “Rota-Rod” technique has been originated by a 1957 paper of N.W. Dunham and T.S. Miya (see paragraph 9.1-Method Papers) and has proved to be of great value in research involving screening of drugs which are potentially active on motor co-ordination.

Ugo Basile designed the first industrial RotaRod in the 1960s. The name we coined soon became so popular, now everybody knows this instrument as RotaRod!The Rota-Rod is the reference test to screen drugs potentially active, or having side effects, on motor coordination.

When a rat falls off its cylinder section onto the trip-box below, the plate boxes and the corresponding magnetic switch is activated, thereby recording the animal endurance time in seconds.

The display shows the actual angular speed (RPM). At the end of a run, the display shows for each animal the running time, the rotation mode and the rotation speed at the time the animal fell off, combined with information preset by the user.

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