Girls are ruining Zeke Meeks' life. Not only is he surrounded by girls at home, he now has a new girl neighbor. She might be good at sports and video games, but when it comes down to it, she is still an awful girl.

Third-grader Zeke Meeks already has two sisters, so he is bitterly disappointed when his new neighbor proves to be a girl--can Charlie change his mind and prove to him that boys and girls can play together?