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File System seems slow/unresponsive: how to measure/test?Well, you can work your way through them - it should (hopefully) be clear which one is maxed out, and it might even tell you if there is a process resource hogging. I also just had an idea for a cause that I will post as an answer (its long)

iTunes 11 Stuttering During PlaybackI've just remembered that I have FileVault enabled, and as the crashes / skips happen when the computer is performing file ops, I think turning FV off might help - decryping my hard drive now...