In this study,we detected anti-HEV and anti-HCV in a group of blood donors in Wuhan areabv enzyme linked immunosorbent assay.The anti-HEV and anti-HCV positive rates were 5.74%and 9.35%,respectively,In plasma donor group,the people who had a elevanted ALT historywere 14.04% for anti-HEV and 14.18% for anti-HCV,and all of them were higher than thosefor the people who had no ALT elevanted history(4.12%and 6.45%,all P<0.01).The posi-tive rates of HBV makers between anti-HEV positive gruup and anti-HEV negative group had nosignificant difference.