After the death of Belushi in 1982, the Blues Brothers have continued to perform with a rotation of guest singers and other band members. The band reformed in 1988 for a world tour and again in 1998 for a sequel to the film, Blues Brothers 2000. They make regular appearances at musical festivals worldwide.

The genesis of the Blues Brothers was a January 17, 1976, Saturday Night Live skit. In it, "Howard Shore and his All-Bee Band" play the Slim Harpo song "I'm a King Bee," with Belushi singing and Aykroyd playing harmonica, dressed in the bee costumes they wore for the "Killer Bees" sketch.

Following tapings of SNL, it was popular among cast members and the weekly hosts to attend Aykroyd's Holland Tunnel Blues bar, which he had rented not long after joining the cast. Dan and John filled a jukebox with songs from many different artists such as Sam and Dave and punk band The Viletones. John bought an amplifier and they kept some musical instruments there for anyone who wanted to jam. It was here that Dan and Ron Gwynne wrote and developed the original story which Dan turned into the initial story draft of the Blues Brothers movie, better known as the "tome" because it contained so many pages.

It was also at the bar that Aykroyd introduced Belushi to the blues. An interest soon became a fascination and it wasn't long before the two began singing with local blues bands. Jokingly, SNL band leader Howard Shore suggested they call themselves "The Blues Brothers." In an April 1988 interview in the Chicago Sun-Times, Aykroyd said the Blues Brothers act borrowed from Sam & Dave and others—"Well obviously the duo thing and the dancing, but the hats came from John Lee Hooker. The suits came from the concept that when you were a jazz player in the 40's, 50's 60's, to look straight, you had to wear a suit".

The band was also modeled in part on Aykroyd's experience with the Downchild Blues Band, one of the first professional blues bands in Canada, with whom Aykroyd continues to play on occasion.[1] Aykroyd first encountered the band in the early 1970s, at or around the time of his attendance at Carleton University in Ottawa, Canada and where his initial interest in the blues developed through attending and occasionally performing at Ottawa's Le Hibou Coffee House. As Aykroyd has said of this time:

So I grew up (in Ottawa), in this capital city. My parents used to work for the government, and I went to elementary school, high school, and the university in the city. And there was a place on Sussex Drive (Sussex Drive is where the Prime Minister's house is, right below Parliament Hill), and there was a little club there called Le Hibou, which in French means 'the owl'. And it was run by a gentleman named Harvey Glatt, and he brought every, and I mean every blues star that you or I would ever have wanted to have seen through Ottawa in the late 50s, well I guess more late 60s sort of, in around the Newport jazz rediscovery. I was going to Le Hibou and hearing James Cotton, Otis Spann, Pinetop Perkins, and Muddy Waters. I actually jammed behind Muddy Waters. S. P. Leary left the drum kit one night, and Muddy said 'anybody out there play drums? I don't have a drummer.' And I walked on stage and we started, I don't know, Little Red Rooster, something. He said 'keep that beat going, you make Muddy feel good.' And I heard Howlin' Wolf (Chester Burnett). Many, many times I saw Howlin' Wolf. And of course Buddy Guy, Buddy Guy and Junior Wells, Sonny Terry and Brownie McGhee. So I was exposed to all of these players, playing there as part of this scene to service the academic community in Ottawa, a very well-educated community. Had I lived in a different town I don't think that this would have happened, because it was just the confluence of educated government workers, and then also all the colleges in the area, Ottawa University, Carleton, and all the schools—these people were interested in blues culture.[2]

The Toronto-based Downchild Blues Band, co-founded in 1969 by two brothers, Donnie and Richard "Hock" Walsh, served as an inspiration for the two Blues Brothers characters. Aykroyd initially modeled Elwood Blues in part on Donnie Walsh, a harmonica player and guitarist, while John Belushi's Jake Blues character was modeled in part on Hock Walsh, Downchild's lead singer. In their first album as the Blues Brothers, Briefcase Full of Blues (1978), Aykroyd and Belushi featured three well-known Downchild songs closely associated with Hock Walsh's vocal style: "I've Got Everything I Need (Almost)", written by Donnie Walsh, "Shotgun Blues", co-written by Donnie and Hock Walsh, and "Flip, Flop and Fly", co-written and originally popularized by Big Joe Turner.[3] All three songs were contained in Downchild's second album, Straight Up (1973), with "Flip, Flop and Fly" becoming the band's most successful single, in 1974.

Belushi's budding interest in the blues solidified in October 1977 when he was in Eugene, Oregon, filming National Lampoon's Animal House. He went to a local hotel to hear 25-year-old blues singer/harmonica player Curtis Salgado. After the show, Belushi and Salgado talked about the blues for hours. Belushi found Salgado's enthusiasm infectious. In an interview at the time with the Eugene Register-Guard he said:

I was growing sick of rock and roll, it was starting to bore me...and I hated disco, so I needed some place to go. I hadn't heard much blues before. It felt good.

Or are you going to make like Mr. Chesterfield and satisfy?
She said that all depends on what you're packing
Regular or king-size
Then she pulled out my Jim Beam, and to her surprise
It was every bit as hard as my Canadian Club

Their style was fresh and in many ways, different from prevailing musical trends: A very raw and "live" sound compared to the increasing use of sound synthesis and vocal-dominated music of the late 1970s and 80s.

While the music of the Blues Brothers is based on R&B, blues, and soul, it also drew heavily on rock and jazz elements, usually taking a blues standard and bringing a rock sound and style to it. The band could be drawn into three sections: the four-man horn section, the traditional rock instruments of the five-man rhythm section, and the two singing brothers. The sound of the band was a synthesis of two different traditions: the horn players all came from the clean, precise, jazz-influenced sound of New York City; while the rhythm section came from the grittier soul and blues sound of Chicago and Memphis. The success of this meld was due both to Shaffer's arrangements and to the musicians' talents.

In Stories Behind the Making of The Blues Brothers, a 1998 documentary included on some DVD editions of the first Blues Brothers film, Cropper noted that some of his peers thought that he and the other musicians backing the Blues Brothers were selling out to Hollywood or using a gimmick to make some quick money. Cropper responded by stating that he thought Belushi was as good as (or even better than) many of the singers he had backed; he also noted that Belushi had, early in his career, briefly been a professional drummer, and had an especially keen sense of rhythm.

With the film, came the soundtrack album, which was the band's first studio album. "Gimme Some Lovin'" was a Top 40 hit and the band toured to promote the film, which led to a third album (and second live album), Made in America, recorded at the Universal Amphitheatre in 1980. The track "Who's Making Love" peaked at No 39. It was the last recording the band would make with Belushi's Jake Blues.

Belushi's wife, Judith Jacklin, and his friend, Tino Insana, wrote a book, Blues Brothers: Private, that further fleshed out the Blues Brothers' universe and gave a back story for the first movie.

In 1981, Best of the Blues Brothers was released, with a previously unreleased track, a version of The Soul Survivors' "Expressway to Your Heart", and alternate live recordings of "Everybody Needs Somebody to Love" and "Rubber Biscuit"; this album would be the first of several compilations and hits collections issued over the years. A 1998 British CD compilation, The Complete Blues Brothers, exclusively features Lamont Cranston's "Excuse Moi Mon Cheri", from the L.A. Briefcase recordings, originally available only as the b-side to the Soul Man 45 rpm single.

After John Belushi's death, updated versions of the Blues Brothers have performed on SNL and for charitable and political causes. Aykroyd has been accompanied by Jim Belushi and John Goodman in character as "Zee" Blues and "Mighty Mack" McTeer. The copyright owners have also authorized some copycat acts to perform under the Blues Brothers name; one such act performs regularly at the Universal Studios Florida theme park in Orlando, Florida and Universal Studios Hollywood.

In 1997, an animated sitcom with Jake and Elwood was planned, but scrapped after only eight episodes were produced.[7]

Aykroyd has continued to be an active proponent of blues music and parlayed this avocation into foundation and partial ownership of the House of Blues franchise, a national chain of nightclubs.

John Belushi's brother, James Belushi, toured with the band for a short time as "Zee Blues," and recorded the album, Blues Brothers & Friends: Live from House of Blues, with Dan Aykroyd but he didn't appear in Blues Brothers 2000. It's rumored he was approached to play not the role of "Mighty Mack" (played by John Goodman), but the role of the local Sheriff "Cab" Chamberlain (which eventually went to Joe Morton). Jim would later reunite with Aykroyd to record yet another album, not as the Blues Brothers but as themselves: Belushi/Aykroyd - Have Love Will Travel (Big Men-Big Music).

In 2004, the musical, The Blues Brothers Revival, premiered in Chicago. The story was about Elwood trying to rescue Jake from an eternity in limbo/purgatory. The musical was written and composed with approval and permission from both the John Belushi estate (including his widow, Judith Belushi-Pisano) and Dan Aykroyd.

The Blues Brothers featuring Elwood and Zee regularly perform at House of Blues venues and various casinos across North America. They are usually backed by James Belushi's Sacred Hearts Band. The rest of the Blues Brothers Band tours the world regularly. The only original members still in the band are Steve Cropper, Lou Marini, and Alan Rubin. The lead singer is Jonny "The Rock & Roll Doctor" Rosch, and they are frequently joined by Eddie Floyd.

Aykroyd currently reprises his character, Elwood Blues, as the host of the weekly House of Blues Radio Hour, heard nationwide on the Dial Global Radio Network.

The Blues Brothers Bar was an illegal backhouse tavern operated on Wells Street In Chicago's Old Town in the 1970s and 1980s which was started by John Belushi and Dan Aykroyd. The Bar was across the street from The Second City theater and in back of the Earl of Old Town night club. In the DVD commentary of the film Thief (a film shot in Chicago in 1981), James Caan mentions the bar. The bar was run by a college friend whom Belushi met at College of DuPage, the friend often operated as a bouncer. As the bar was unlicensed, alcohol was bought by the purchase of 'tickets' which were then traded to the bartender for the drinks. The bar was discovered by authorities in 1982 and was forced to close shortly after.

A bar by a similar title was built in Mount Prospect, Illinois (referenced in the movie as the town where Elwood purchased the car) opened in 2007.

In Springfield, Illinois, a moderately successful establishment known as Jake & Elwood's Pizza served the area with a blues style setting and Chicago style pizza, along with a great deal of Blues Brothers memorabilia. The restaurant closed in 2003.

The 1978 release and success of Briefcase Full Of Blues sparked a renewed interest in the genres of blues, rhythm and blues, and jazz, especially in a much younger audience. With two tracks listed in the Top 40, and the unique sound and lyrics of "Rubber Biscuit" a new audience was discovered that was heretofore unfamiliar with the styles. Wayfarer sunglasses, black suits with skinny black ties, and pork pie hats became the dress of choice for many aspiring blues, and rock and roll musicians. The 1980 film The Blues Brothers provided a venue for many venerated and renowned acts introducing a willing audience to previously unfamiliar artists.

There have been many takeoffs and parodies of the Blues Brothers, most notably in the Chicago area. The Whitehall Theatre in London, England, staged A Tribute to the Blues Brothers in 1996. What was originally a six-week run extended into 46 and was staged on and off till 2001. Guest-stars included Antonio Fargas singing "Minnie The Moocher".[9]

^Acykroyd is playing with Downchild in the fall of 2009, during the band's 40th anniversary tour: "...when one thinks of blues music in Canada, the first name that springs to mind is DOWNCHILD. It's been 40 years since Donnie 'Mr. Downchild' Walsh and his late brother Hock, formed the renowned group that would be the inspiration for the world famous Blues Brothers. DOWNCHILD plans to celebrate this anniversary in style, with some very special friends--including blues brother and movie icon DAN AYKROYD." News Release, July 21, 2009; www.downchild.com. See also Cross Reference At Blues Brothers Central; www.bluesbrotherscentral.com, where it is also mentioned that when the Blues Brothers played the Casino Rama in 2005, Donnie "Mr. Downchild" Walsh appeared as their guest.