In recent years it has been suggested that the hormone leptin plays an important role in the Jump to Obesity and leptin resistance: Although leptin is a circulating signal that reduces appetite, obese When the so-called fat-controlling hormone leptin was first discovered, scientists predicted it would be Emerging evidence from both animal and human studies indicates that leptin may play an important role in obesity Genetics of leptin and obesity: a HuGE review. Paracchini V, Pedotti P, Taioli E. Unit of Molecular and An obesity wonderdrug called Leptin that failed to live up to its expectations when first discovered by The discovery more than a decade ago of leptin, an appetite-suppressing hormone secreted by fat