The city got its name from the single, large spring that issued into a small gorge between the base of Scenic Mountain and a neighboring hill in the southwestern part of the city limits. Although the name is sometimes still mistakenly pluralized, it is officially singular. "To the native or established residents who may wince at the plural in Big Springs, it should be explained that until about 1916, when for some unexplained reason the name dropped the final "s," the official name of the town was indeed Big Springs." [3] There is also a small community named Big Springs, Texas, located in Rusk County in East Texas.

According to the United States Census Bureau, the city has a total area of 19.2 square miles (50 km2). About 19.1 square miles (49 km2) of it is land, and 0.1 square miles (0.26 km2) of it (0.42%) is covered with water.

The area's "big spring", long dry but recently modified to draw water from Comanche Trail Lake, was of major importance to all life in the surrounding area. In the early 1840s, it was the center of a territorial dispute between Comanche and Pawnee tribes, and has been a major watering hole for wildlife and prehistoric man in this semiarid area.[5] Early military scouting reports and pioneer accounts describe the water as cold, clear, and dependable; the spring pool was approximately 15 feet (5 m) deep, with the overflow going only a short distance down the draw before it sank beneath the surface. The spring has mistakenly been described in other writings as being located in Sulphur Draw. It is actually located to the south, near the top of a small, rugged, unnamed draw running eastwards from the spring, and is itself a tributary to Beal's Creek, the name given to Sulphur Draw as it flows into, through, and past the city of Big Spring.

Long used by regional inhabitants, both permanent and nomadic, with a large number of locally collected artifacts testifying to its heavy occupation, the spring sat astride the several branches of the later-developed Comanche War Trail as they converged on this important water hole from beyond Texas, coming south across the Northern Plains and the Llano Estacado. From the Big Spring, the war trail continued south via three branches, one to the southeast through the western part of the Concho country; one going almost due south, heading for Castle Gap and Horsehead Crossing on the Pecos River; and one heading west to Willow Springs in the sand country southwest of present Midland, before turning south down the Pecos, all headed ultimately for Mexico. As whites began to settle the western territories, the spring continued to serve as a major watering place on the southern route of the Gold Rush Trail of the early 1850s and continued in use well beyond that time, as the cross-continental trail turned into a major road for later pioneers coming into the area.

The spring was sourced from a relatively small aquifer situated on the northern end of the Edwards Plateau and the southern end of the High Plains, being, structurally, a collecting sink of lower Cretaceous (Fredericksburg) limestones and sands.[5] The spring aquifer held a large quantity of water due to the great number of fractures, solution channels, and interstices in the rocks and underlying sands, although the aeral extent of the Big Spring sink is estimated to be only 1 mile (2 km) in diameter, with the main area only 3,000 feet (914 m) wide and almost circular, with some ellipticity trending towards the west. The Cretaceous beds subsided about 280 feet (85 m) below their normal position, centered on the SE quarter of Section 12, Block 33 T1S; T&P RR Co survey, and the entire stratum appears to be preserved within the sink, the surface topography roughly following the subsurface subsidence.[6] This writing identifies the sink as one of a number of similar subsurface geologic features in the surrounding area, differing from the Big Spring sink only in the fact that the surface topography above the others, while showing some decline, does not dip low enough to intersect the top of the water tables; hence, no springs could form from the other aquifers. In a passing comment, enigmatic in its content and disappointing in its brevity, the report states no other comparable deep sinks formed elsewhere on the Edwards Plateau.

The same publication suggests the spring's discharge volume was in excess of 100,000 US gallons (378,541 L) per day at the time of the railroad's arrival in the area in the late 1880s. The water was heavily mined by wells built by both the railroad and the early town of Big Spring, greatly in excess of its modest recharge rate, until the water table first dropped below the level of the spring outlet, and, finally, was completely depleted by the mid-1920s. The city now artificially fills the spring from its current source of water as a means of allowing residents and visitors to maintain some idea of how it appeared in times past.

Although the area had long been a popular watering hole for Native Americans and other prehistoric residents and nomads, including members of the more recently established Jumano, Apache, and Comanche tribes, the first European to view the site now known as Big Spring was probably a member of a Spanish expedition, possibly that of Álvar Núñez Cabeza de Vaca, although the record of his travels cannot confirm his visit.

One notable early rancher was Briton Joseph Heneage Finch, the Seventh Earl of Aylesford. Finch purchased 37,000 acres (150 km2) of ranch land in the area in 1883, and is credited with building Big Spring's first permanent structure, a butcher's shop.[9]

The completion of the Texas and Pacific Railroad led to the founding in the early 1880s of Abilene, Colorado City, and Big Spring, three railroading and ranching cities where saloons and gambling dens flourished.

More important in the city's history was the discovery of oil in the region during the 1920s. The early discoveries in the area marked the beginning of the oil industry in the Permian Basin area of West Texas, and the oil industry has continued to be a dominant part of the area's economy. The oil industry in Big Spring reached its peak during the oil boom of the 1950s.

Another major part of Big Spring's economy and life during the 1950s, 1960s, and 1970s was Webb Air Force Base. It initially opened during World War II as the Big Spring Bombardier School. Following the war, it was converted to a US Air Force training base and was named for James Webb, a Big Spring native who died in action during World War II. Webb Air Force Base was active until 1977, when the base facilities were deeded to the city.

Big Spring was also featured in the 1969 film Midnight Cowboy, which starred Dustin Hoffman and Jon Voight and received the Academy Award for Best Picture of 1969. The opening scenes featuring Voight, then a relatively unknown actor, playing the character Joe Buck were filmed in Big Spring and the neighboring city of Stanton.

In 1980, Hollywood returned to Big Spring with the filming of Hangar 18.[10] It was a low-budget sci-fi movie about a space shuttle's collision with an alien spacecraft and the ensuing government cover-up. It starred such big names as Gary Collins, James Hampton, Robert Vaughn, Darrin McGavin and a host of other B-list actors, including Stuart Pankin, who at that time was relatively unknown. The film received low marks, both in critics' reviews and box-office earnings. Despite its poor performance, it became an instant cult classic, appearing on television under a different title and featuring an alternate ending. Several local residents were used as on-screen extras.[11]

Of the 8,155 households, 32.8% had children under the age of 18 living with them, 48.3% were married couples living together, 14.1% had a female householder with no husband present, and 33.0% were not families. About 29.2% of all households were made up of individuals, and 14.6% had someone living alone who was 65 years of age or older. The average household size was 2.51, and the average family size was 3.10.

In the city, the population was distributed as 23.6% under the age of 18, 9.9% from 18 to 24, 32.7% from 25 to 44, 19.7% from 45 to 64, and 14.1% who were 65 years of age or older. The median age was 35 years. For every 100 females, there were 125.2 males. For every 100 females age 18 and over, there were 132.3 males.

The median income for a household in the city was $28,257, and for a family was $35,448. Males had a median income of $27,636 versus $21,863 for females. The per capita income for the city was $14,119. About 17.1% of families and 22.2% of the population were below the poverty line, including 30.0% of those under age 18 and 18.3% of those age 65 or over.

The Texas Department of State Health Services operates a 200-bed psychiatric hospital, opened in 1939. The hospital has reduced its number of beds over the years, but remains one of the largest employers in Big Spring.

Big Spring is the site of several major hang gliding championship tournaments, including the U.S. Hang Gliding Nationals.[18] The city was also the site for the filming of parts of Midnight Cowboy and Hangar 18.[19]

J. T. Smith, wide receiver for the St. Louis and Phoenix Cardinals, Washington Redskins and Kansas City Chiefs, played 13 years in the NFL, then coached the San Angelo indoor team. He played at North Texas State after finishing at Big Spring High School. He was inducted to the Big Spring Hall of Fame in 2002. JT was named to the AFC Pro Bowl team in 1980 and the NFC Pro Bowl team in 1988. He also led the NFL in total punt returns in 1979 and 1980.