Vanderbilt University's Center for Technology Transfer and Commercialization provides a variety of intellectual property-related services to Vanderbilt researchers, including innovation identification, protection, marketing and licensing. The Center also works with investment professionals, angel investors and experienced management teams to identify technologies that are appropriate for a commercialization strategy involving a start-up company. Vanderbilt currently maintains a portfolio of 20 active start-up companies that span a range of technologies including computerized surgical navigation, natural products for insect control, clinical information management systems, clinical diagnostics, drug discovery, radiation therapy and healthcare services. In fiscal year 2012, 40 U.S. patents were issued for Vanderbilt technologies, and 60 new licenses were granted to facilitate the transfer of scientific discovery and innovation to the commercial marketplace.

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