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Bio-ARROW help

In the context of the NIH Guidelines, recombinant and
synthetic nucleic acids are defined as: (i)
molecules that a) are constructed by joining nucleic acid molecules and
b) that can replicate in a living cell, i.e., recombinant nucleic acids; (ii)
nucleic acid molecules that are chemically or by other means synthesized or
amplified, including those that are chemically or otherwise modified but can
base pair with naturally occurring nucleic acid molecules, i.e., synthetic
nucleic acids, or (iii) molecules that result from the replication of those
described in (i) or (ii) above. If you
are using DNA primers for PCR, you do not need to check the box “recombinant or
synthetic DNA/RNA materials, including human gene therapy.”

Biological toxins are defined as toxins produced by
microorganisms, animals and plants. Chemicals or products which are considered toxic are not considered
biological toxins. For a list of
biological toxins and corresponding LD50 values, see the University of
Florida’s EH&S webpage (http://www.ehs.ufl.edu/programs/bio/toxins/toxin-table/).

If your research does not fall into any of the categories
listed on this page, you likely do not need to file a biosafety protocol. We are no longer requiring a biosafety protocol
for work with chemicals and animals; this work should be covered in your lab’s
Chemical Hygiene Plan and Animal Protocol. Call our office (608-263-2037) to verify your work does not require a
biosafety protocol.