A pro-Russian militant holding a bat guards a barricade in front of the Donetsk regional administration building on April 8, 2014.

Dozens have been arrested as Kiev authorities launched a crackdown on anti-Maidan activists in cities of eastern Ukraine that attempted to declare their independence.

At least 70 activists have been arrested after a so-called “anti-terrorist operation” launched by Ukraine’s Interior Ministry in the eastern city of Kharkov.

According to the country’s interior minister, Arsen Avakov, “the building of the regional state administration is totally free of the separatists who seized it earlier.”

On Monday, Kharkov protesters erected barricades around administrative buildings and the regional headquarters of the Ukrainian Security Service (SBU). The demonstrators soon took control of the building.

This was followed by clashes with police who reportedly unleashed fire-hoses, stun grenades and tear gas to push the crowd back from the building. In response, protesters threw several Molotov cocktails at the building and set a pile of tires on fire. The blaze soon spread to the first floor of the building.

Eventually, a group of local police outside the administration building moved in to push protesters back, allowing fire crews to extinguish the blaze. The building was slightly damaged by the blaze and several windows were broken in the scuffles.

Activists at the scene said the law enforcement officers who used force against protesters had been deployed from western Ukraine. According to some witnesses, the violence was initially triggered by a group of provocateurs.

Despite the crackdown, a group of at least 150 people gathered in front of Kharkov’s administration building Tuesday to protest against the new authorities in Kiev.

In Donetsk, activists proclaimed the creation of a People’s Republic of Donetsk after seizing the local administration building.

This action on Monday was also followed by a special operation. Police took weapons seized by the protesters in the SBU’s regional headquarters, Donetsk Mayor Aleksandr Lukyanchenko said.

A woman raises her fist as pro-Russians demonstrate in front of the Donetsk regional administration building, held by pro-Russian militants, on April 8, 2014.

Ukrainian media however report that the self-proclaimed People’s Republic of Donetsk has ceased to exist.

“The Committee on Patriotic forces of Donbass has been receiving numerous calls from the public voicing their disagreement with the proclamation of the republic and its joining the neighboring state as well as conducting a referendum – all those without a legal base in place,” Ukrainskaya Pravda daily cited the committee said as saying.

The proclamation and referendum plans were thus annulled till the legal base is created, the committee said. The group’s original posting on Facebook has become unavailable.

On Tuesday, protesters gathered in Lugansk – also outside the regional department of the SBU. Interfax-Ukraine reported that the protesters were setting up barricades and pouring flammable mixtures on them.

The speakers at the demonstration called for the creation of a parliament of the Lugansk republic, choosing new MPs and establishing a new government. Calls for an independence referendum were also heard.

On Monday, clashes erupted in the southern Ukrainian city of Nikolaev after at least 300 activists attempted to storm the city administration building. The protesters were also trying to remove the Ukrainian flag from the administration building. Police reportedly used rubber bullets to force the crowd back from the building.

At least 15 people have been injured, with 11 of them were admitted to hospital, and more than 20 arrested, the city’s Health Department reported.

An elderly woman looks at the Russian flag set up by pro-Russian activists at a barricade blocking access to the Ukrainian Security Service building in the eastern Ukrainian city of Lugansk on April 8, 2014.

After pro-Russian demonstrators expressed their discontent with Kiev authorities in the city of Dnepropetrovsk, the city authorities moved to negotiate with the anti-government activists.

According to the region’s deputy governor, Boris Filatov, both the “left-wing” and the pro-Russian protesters agreed to refrain from “calls for separatist actions.” In return, the authorities said they will let the activists use some offices in the administrative buildings for their “meetings and work,” as well as provide them with “free access” to local printed media.

Meanwhile, Russia has called on Kiev and Washington not to ignore the interests of all of Ukraine’s regions, including those in southeastern Ukraine. The Russian Foreign Ministry voiced concerns over the build-up of Ukrainian forces and US mercenaries in southeastern parts of the country, calling on Kiev to immediately cease military preparations which could lead to a civil war.

According to Russian FM Sergey Lavrov, the coup-appointed government in Ukraine has not made any positive steps towards these regions and the people there “fear that their interests are being ignored by Kiev.”