GeneReviews, an international point-of-care resource for busy clinicians,
provides clinically relevant and medically actionable information for inherited conditions
in a standardized journal-style format, covering diagnosis, management, and genetic counseling for patients and their families. Each chapter in GeneReviews is
written by one or more experts on the specific condition or disease and goes through a
rigorous editing and peer
review process before being published online.

GeneReviews currently comprises 777 chapters.

The two general formats for GeneReviews are: chapters focused on a single
gene or phenotype (~95%) and overviews summarizing genetic causes of common conditions
(e.g., deafness and hearing loss, Alzheimer disease) (~5%).

To ensure continuing relevant and medically actionable content, each
GeneReviews chapter is updated every two to four years (or as needed) by the
author(s) in a formal and comprehensive process curated by the GeneReviewseditors. Additional revisions may occur more
frequently as needed to reflect significant changes in clinically relevant information.

Genetic counseling and testing terms used in GeneReviews are hyperlinked
to definitions in the GeneReviewsGlossary. Resource Materials include additional information on key
genetics concepts used in GeneReviews.

GeneReviews are indexed in PubMed.

Note: For a variety of reasons, GeneReviews occasionally removes chapters from the active website. Click here for a list of archived chapters.