This is a 34-year-old-woman, G3P2, with no known obstetric risk factors and with no relevant medical history. The patient did not develop fever during the first and second trimester of pregnancy. The nuchal translucency was 1 mm

for 54 mm CRL. The triple test was 1:2000. The fetal growth was normal. The second scan at 22 weeks was normal.

An amniocentesis was performed in emergency. Fetal karyotype was normal, but we found CMV on the amniotic fluid byPCR technique. At 37 weeks, the ventriculomegaly has increased. A fetal cerebral MRI was done: All the anomalies were confirmed.

The patient consulted a neuro-pediatrician for explanation about the poor fetal neurological prognosis (failure to thrive, infantile spasms and seizures, deafness, etc…). The patient decided to end pregnancy at 37 weeks.

This is the first pregnancy. The first ultrasound was normal. The second one at 23 weeks showed remarkable ascite and small head with relative ventriculomegaly, destruction of septum pellucidum, small cerebellum; calcified foci in brain, liver and splenic area.