Download to ...

Share this article

Email updates

Keep up to date with the latest news and content from Journal of Biology and BioMed Central.

Research news

Tracking evolution's footprints in the genome

Jonathan B Weitzman

Journal of Biology 2003, 2:9
doi:10.1186/1475-4924-2-9

Published: 23 June 2003

Abstract

The strategy of using 'phylogenetic footprinting' to find regulatory sites that are
conserved between pairs of related complex genomes has led to the development of a
suite of computational tools that succeed in finding functionally important transcription-factor-binding
sequences.