Lightroom: "Edit In..." no longer works consistently in Lightroom 5.4

After the upgrade, I cannot consistently get photos to export to Photoshop CC for editing. It works 20% of the time, and the other 80%, nothing happens. I don't know what factors cause it to work/not work. It does not work for Nik Software either.

I had LR 5.3 installed and I downloaded the LR5.4 update this afternoon on my Win 7 64 bit Desktop, and afterwards none of the Nik plugins would open and l got an AppCrash error. I uninstalled my current version of Nik, rebooted and download again from the site and installed the newer version of Nik. This did not fix the problem and I have not found any postings with a fix. I then booted my Win8.1 64 bit Laptop still running LR 5.3 and the Nik Collection works fine as it did on my Desktop prior to the LR upgrade. I think LR 5.4 upgrade broke the Nik plugins.

I did exactly the same (downloaded the LR5.4 update) on my Win 8.1 machine - Nik plugins continue to work flawlessly with 5.4. So at least for Win 8.1. the plugins can't be the issue. Did you maybe install LR 5.4 to a new directory different from LR 5.3?

I always install to the software executable default folder. But I noticed that it did install to a new 5.4 subfolder inside my PF\Adobe folder. It also removed the Adobe Photoshop Lightroom 5.3 folder that used to be there. It also created a new desktop shortcut.
This seems to me to be a full version and not a patch.

I'd try another cycle of removing the plugins, rebooting the computer and installing the Nik collection again. I doubt that the plugins are incompatible with LR 5.4/Win 7. They definitely aren't on Win 8.1, as I wrote. ... No other ideas, I'm afraid ...

It seems that "edit in" works with most jpgs, but it is very spotty with NEF files. Some files will open in PS or Nik, but the file next to it won't, even after trying multiple times. I'm imagining that it won't work with groups of files if the group contains a "bad" image. What makes the image "bad" is beyond me. It edits fine in LR, and the disk is in good health.

I am seeing the same thing. RAW/DNG files will not open in Photoshop CC no matter what I try. I have tried opening both NEF and ORF RAW formats. They don't even pop up the dialog box that lets you choose to edit a copy/original. JPG/TIF will pop up the dialog box. If I use "Edit with Lightroom adjustments" they will not open. Editing a copy or the original seems to work fine.

I also tried uninstalling Photoshop CC and falling back to Photoshop CS5 and that works without any issue. So it seems to be the combination of LR 5.4 and PSCC that is causing the issue. I am running OS X 10.9.2

Update: RAW files will open in PSCC as Smart Objects but when I try to save it I get the error in the image.

If you don't already have a config.lua file here is how you create it-

Make a text file named "config.lua" in the folder containing Lightroom presets. Lightroom must be restarted before any configuration changes will take effect.
Mac OS :
~/Library/Application Support/Adobe/Lightroom

The fastest way to find the location of the config.lua file is use go into Lightroom's preferences dialog, switch to the Presets tab, and click "Show Lightroom Presets Folder". That will reveal the folder in Explorer/Finder. The config.lua file goes at the root of the "Lightroom" folder at this location.

In case it helps:
Lightroom 5.4 and Photoshop CS5 were installed before I subscribed to CC. I removed the previous versions and installed LR 5.4 and PSCC using the CC launcher. In terms of plugins I have Nik Software, Photomatix, and onOne installed. Sending files to all of those works fine. I tried uninstalling PSCC and re-installing CS5 and everything works fine in CS5.

Is there any way to turn on debugging? Would running it from the terminal provide any useful output?

1. Create a second editor in LR that points to your older copy of CC (pre-2014 version)
2. Manually launch CC-2014
3. To edit a picture, right click as usual, but choose edit in "Photoshop.exe" rather than CC 2014. It will give you the usual dialog box (make copy, etc) and then go into the already open PS-CC-2014

Unfortunately I think that work around only works on a Windows PC. I tried it on my Mac and I can have PS CS5, CC, and CC 2014 open at the same time.

I have gotten around this by using a more manual process.

1. In LR create "To Edit" and "Edited" folders inside the folder that contains my images. I do this for each folder in my library.
2. Make my adjustments in LR
3. Export as TIFF to "To Edit" folder
4. Open PS CC, make my edits, save to "Edited" folder
5. In LR, right click on main folder and select "Synchronize Folder..."

In the interim, I went into LR and told it to add another editor, then added the previous version of PS. Whenever I started LR, I also started the NEW PS CC but then in LR I chose the alternate (old) PS as editor. Since the NEW CC was open and it has the same exe name, the image opened there.

The ultimate solution was to reinstall Windows and everything else. I needed a larger hard drive anyway.