Comprised of premier Midtown Manhattan luxury accommodations, Hotel 48LEX is located on 48th Street and Lexington Avenue, where all of the city’s attractions are within arm’s reach. Our neighborhood shines with Broadway theaters, iconic 5th Avenue shopping, the Empire State Building, Times Square, and a wealth of world-famous museums. Stay with us at one of the finest Manhattan luxury hotels and step right into the heart of the greatest city in the world.