IVF SUCCESS RATE:

How to find the Right IVF Centre? What is an acceptable success rate in IVF? How many times a couple should attempt IVF?

Every Couple walks into our IVF Centre with a Hope and Belief of 100% Success following IVF.

IVF Success Rates- means- the percentage of all IVF cycles which result in a favourable outcome i.e. Pregnancy. Depending on the type of calculation used, this outcome may represent the number of confirmed pregnancies, called the Pregnancy Rate or number of live births, called the Live Birth Rate

Due to rapid advancement in reproductive technology, the IVF success rates have become substantially better than they were a few years ago.

Unfortunately, in India – no national figures on success of IVF are available. ICMR is in the process of registering all IVF clinics in India.

It is of course 100% for the couple who gets a live baby after IVF and for the one who fails, its 0%.

Each IVF treatment cycle is a bit like taking a gamble i.e.”One needs to hope for the best and prepare for the worst”!!

HOW MANY IVF CYCLES ARE TO BE TRIED?Infertile couple should go through at LEAST 3 CYCLES. to give them a fair chance of live birth rate. With 3 treatment cycles, the chance of getting pregnant (the cumulative conception rate) is about 65-75%.

The chance of getting pregnant in a Single IVF-ICSI cycle is more than 30-35% in Male Factor Infertility. Over 3 ICSI - IVF cycles, the chance of having a baby increases to good 70- 80%.

These days, it is not uncommon to find request from couple for Nth Number of cycles. Experts believe that after 3 cycles if couple is willing for Donor Eggs cycle – one can go further.

“Beware of IVF Centre which claims 70 -80% Success Rates in One treatment of Cycle”.

Let us assume the pregnancy rate for IVF of IVF-ICSI cycle at a given IVF centre is 30%. This is least expected from a good IVF – ICSI centre any where in the world.

EXERCISE FOR CLEAR UNDERSTANDING: If 10 patients start an IVF of IVF – ICSI cycle, 3 will get pregnant, leaving 7 patients. If these 7 patients try another IVF cycle, 2 will be pregnant. Two more will get pregnant in 3rd cycle. So out of 10 patients who started, minimum 7 or 8 will be pregnant in three attempts. This is because the chance of getting pregnant in the next IVF cycle do not decrease just because a pregnancy has not occurred in the previous IVF cycle. So that the best bet would be to keep on trying for atleast three cycles.

KEY FACTORS FOR SUCCESS:The main potential factors that influence pregnancy (and live birth) rates in IVF have been suggested to be maternal age, duration of infertility , BMI Serum AMH level and Antral Follicle Count, all reflecting ovarian function. Optimal woman's age should be 23–39 years at time of treatment.

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