Previous GeneCards Identifiers for POU3F3 Gene

Summaries for POU3F3 Gene

Entrez Gene Summary for POU3F3 Gene

This gene encodes a POU-domain containing protein that functions as a transcription factor. The encoded protein recognizes an octamer sequence in the DNA of target genes. This protein may play a role in development of the nervous system. [provided by RefSeq, Apr 2015]

GeneCards Summary for POU3F3 Gene

POU3F3 (POU Class 3 Homeobox 3) is a Protein Coding gene.
Diseases associated with POU3F3 include Central Nervous System Tuberculosis and Agraphia.
GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and HMG box domain binding.
An important paralog of this gene is POU3F2.

UniProtKB/Swiss-Prot for POU3F3 Gene

Transcription factor that acts synergistically with SOX11 and SOX4. Plays a role in neuronal development. Is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the octamer motif (5-ATTTGCAT-3) (By similarity).

Molecular function for POU3F3 Gene

Transcription factor that acts synergistically with SOX11 and SOX4. Plays a role in neuronal development. Is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the octamer motif (5-ATTTGCAT-3) (By similarity).