As a rule of thumb, it is profoundly unwise to take crack-cocaine. The brain has evolved a truly vicious set of negative feedback mechanisms. Their functional effect is to stop us from being truly happy for long. Nature is cruelly parsimonious with pleasure. The initial short-lived euphoria of a reinforcer as powerful as crack will be followed by a "crash". This involves anxiety, depression, irritability, extreme fatigue and possibly paranoia. Physical health may deteriorate. An intense craving for more cocaine develops. In heavy users, stereotyped compulsive and repetitive patterns of behaviour may occur. So may tactile hallucinations of insects crawling underneath the skin ("formication"). Severe depressive conditions may follow; agitated delirium; and also a syndrome sometimes known as toxic paranoid psychosis. The neural aftereffects of chronic cocaine use include changes in monoamine metabolites and uptake transporters. There is down-regulation of dopamine D2 receptors to compensate for their drug-induced overstimulation. Thus the brain's capacity to experience pleasure is diminished.

He was a normal guy until he started smoking crack, now he is a hustler that sucks dick for $5 to buy another rock.

Otherwise known as crack-cocaine, this illegal drug is a mixture of two parts cocaine and one part baking soda. This chemical process reverts the powder-cocaine mkaing process by one step, producing a smokable form of the naturally found alkaloid cocaine. Because of its nature as an inhalable substance, the high is quicker and more intense, leading to a larger number of addicts. In present society, it is considered to be much more distasteful to use crack-cocaine then powder-cocaine as crack is mainly viewed as a drug for poor people whereas powder cocaine is used by a richer constituancy. Contrary to popular belief, crack-cocaine is not freebase cocaine. Freebase cocaine is a mixture of cocaine, ether, and other dangerous and combustable materials. Baking soda was replaced as the ingredient in the 1980's to make production easier and less dangerous. Either way, crack and freebase cocaine produce the same smokable form of the drug.

crack-cocaine is usually found in poor black neighborhoods in the ghetto whereas powder-cocaine is found in rich white suburban neighborhoods.