Jon C Rees, a researcher well published in scientific journals, has developed a remarkable hypothesis that the root cause of obsessive compulsive disorder (OCD) and pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) may be due to dysfunction in the gut microbiome.

Rees suggests that this gut dysfunction may result in susceptibility to obsessional thinking. The role of stress and antibiotics in altering gut flora is discussed. The journal abstract (link below) has been released prior to the print publication. The article will appear in Medical Hypotheses.