Organizing a cell's genetic material from the sidelines

A tremendous amount of genetic material must be packed into the nucleus of every cell -- a tiny compartment. One of the biggest challenges in biology is to understand how certain regions of this highly packaged DNA can be called upon so that the genes encoded in them can be ''turned on'' and used to manufacture RNA and proteins. New work sheds light on this process with implications for age-related diseases and organ decay.
Source: Medicine Science Daily