Gilenya

OVERDOSE

GILENYA can induce bradycardia as well as AV conduction
blocks (including complete AV block). The decline in heart rate usually starts
within 1 hour of the first dose and is maximal within 6 hours in most patients [see
WARNINGS AND PRECAUTIONS]. In case of GILENYA overdosage, observe patients
overnight with continuous ECG monitoring in a medical facility, and obtain
regular measurements of blood pressure [seeDOSAGE AND ADMINISTRATION].

Neither dialysis nor plasma exchange results in removal
of fingolimod from the body.