SNP Genotyping Assays

Search all TaqMan™ SNP Genotyping Assays,
including Drug Metabolism Genotyping Assays, and assays that are
functionally tested or validated.

Drug Metabolism Assays

Drug Metabolism Assays

These assays are specifically
designed to detect polymorphisms in 221 genes that code for
various drug metabolism enzymes and drug transporters. Assays are
tested using gDNA from 45 individuals from four ethnicities. The
minor allele frequency for each population is available, but rare
and mutant alleles may not be present in the test DNA.

Which Copy Number product(s) are you interested in using?

All Copy Number Assays

All Copy Number Assays

Search all TaqMan™ Copy Number Assays and required
TaqMan™ Copy Number Reference Assays.

Markers & Reporters

Markers & Reporters

Marker & Reporter assays are
designed to detect the copy number of marker and reporter genes
from expression vectors that have been introduced into cells or
animals, such as the lacZ reporter gene or antibiotic genes.

Recommended Use: Animal experiments

Ambion® In Vivo siRNAs are designed using the Silencer®
Select algorithm and incorporate chemical modifications that help
provide superior serum stability for in vivo delivery.

Stealth RNAi™ siRNA

Recommended Use: Continuity in cell culture and animal experiments

Stealth RNAi siRNAs uses their
proprietary chemical modifications for restricting off-target
effects and their effective algorithm for providing efficient
knockdown. They are recommended for completing in vitro RNAi
studies that were started using Stealth siRNAs. For new studies,
we recommend Ambion Silencer Select siRNAs.

Unmodified siRNA

Recommended Use: Continuity in cell culture experiments

Silencer® siRNAs are designed using our
first-generation algorithm and do not include any chemical
modifications. They are recommended for completing in
vitro RNAi studies that were started using Silencer®
siRNA. For new studies, we recommend Silencer®
Select siRNAs.

What gRNA format would you like to use?

TrueGuide Modified Synthetic crRNA

TrueGuide Modified Synthetic crRNA

TrueGuide Modified Synthetic crRNAs are hybridized with TrueGuide tracrRNA to form a gRNA complex that directs Cas9 to the editing site.
The efficiency of the TrueGuide 2 piece gRNA system is enhanced by the addition of 2’O-meythl analogs and 3’ phosphorothioate internucleotide linkages
that enhance editing efficiency by increasing binding to the target site and inhibiting nuclease degradation, respectively.
Note: for this format requires the purchase of separate TrueGuide™ crRNA and TrueGuide™ tracrRNA products, which are annealed to generate a crRNA:tracrRNA duplex prior to delivery into cells.
Be sure to add the TrueGuide tracrRNA to cart when ordering TrueGuide™ crRNA.

TrueGuide Modified Synthetic sgRNA

TrueGuide Modified Synthetic sgRNA

TrueGuide Modified Synthetic sgRNAs are 1 piece, chemically synthesized, 100-mer gRNAs that incorporate 2’O-meythl analogs and 3’ phosphorothioate
internucleotide linkages in the terminal three nucleotides on the on both the 5’ and 3’ ends of the gRNA.
These modifications enhance editing efficiency by increasing binding to the target site and inhibiting nuclease degradation, respectively.

TrueGuide Synthetic sgRNA

TrueGuide Synthetic sgRNA

LentiArray Lentiviral sgRNA

LentiArray sgRNA are sgRNAs pre-packaged as ready to use lentiviral
particles. LentiArray sgRNAs provide the versatility to apply CRISPR
based editing to a wide variety cell lines including hard to transfect cell lines.

Primary MicroRNA Assays

Mimics

Small, synthetic, double-stranded RNA molecules designed to mimic
endogenous mature miRNAs. They are supplied ready-to-use; they
can be introduced into cells using transfection or
electroporation. We recommend mirVana™
miRNA Mimics, but we continue to offer Ambion®
Pre-miR miRNA Precursors for completion of studies that were
started using these first-generation products.

Inhibitors

Small, synthetic, single-stranded RNA molecules designed to
specifically bind to and inhibit mature miRNAs from functioning.
We recommend mirVana™ miRNA inhibitors,
but we continue to offer Ambion® Anti-miR™
miRNA Inhibitors for completion of studies that were started
using these first-generation products.