Sierra Platinum

DNA bound proteins such as transcription factors and modified histone proteins
play an important role in gene regulation.
Therefore, their genomic locations are of great interest.
Usually, the location is measured using ChIP-seq and analyzed using a peak-caller.
Replicated ChIP-seq experiments become more and more available.
Sierra Platinum allows
to call peaks for several replicates and also provides a variety of
quality measures.
Together with integrated visualizations, the quality measures
support the assessment of the replicates and the resulting peaks.
Sierra Platinum outperforms other methods.
We here provide Sierra Platinum Service: the first webserver for multi-replicate peak-calling.

Usage Instruction

Provide an email-address and start your own Sierra
Platinum server for peak calling. We will notify you by
email once the server is ready to accept your
job. Your server will run 72 hours in
total.