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INTERVENTIONAL VASCULAR CORPORATE AND REGIONAL PRESS RELEASES

BTG plc (LSE: BTG), the global healthcare company, today announced the publication of data showing that cancer patients with presumed methotrexate toxicity treated with Voraxaze® (glucarpidase) had shorter hospital stays, lower in-patient mortality, and lower 90-day mortality than those treated with conventional treatment. The study, based on a retrospective review of Medicare claim data, was published in the journal ClinicoEconomics and Outcomes Research.

BTG plc (LSE: BTG), the global healthcare company, today announced the first patients outside of a clinical trial have been successfully implanted with the BTG Sentry device – the world’s first bioconvertible IVC filter. The BTG Sentry filter is designed to provide protection from Pulmonary Embolism (PE) for the period of transient risk and then bioconvert to leave a patent, unobstructed IVC lumen, eliminating the need to retrieve and addressing the typical filter-related complications associated with conventional IVC filters.

BTG plc (LSE: BTG), the global healthcare company, announced today that the first EKOS™ CU 4.0 units have been shipped from BTG’s facility in Bothell (Washington, US) to Europe, where full commercial launch will begin. New features of the EKOS™ CU 4.0 include an interactive colour touchscreen, a built-in battery and separate ports for managing two EKOS™ devices simultaneously.

BTG plc (LSE: BTG), the global healthcare company, announces that Garry Watts has informed the Board that he wishes to retire as Chairman and Non-executive Director of the Company. The Board has commenced a process to appoint a successor to Mr Watts, who will continue as Chairman until 31 December 2018.

BTG plc (LSE: BTG) today announced a policy for replacement of expired vials of CroFab® Crotalidae Polyvalent Immune Fab (Ovine), allowing customers to return the product for replacement up to 90 days after expiration. This change goes into effect immediately, and provides CroFab®customers with a process for replacing their expired product at no charge. CroFab® is the only available FDA-approved product for the management of all North American pit viper envenomations in adult and pediatric patients.1