The aim of the National Data Basis for Palliative Care is to map and to describe the end of life and the way of dying in the Czech Republic, based on available data sources in the National Health Information System (NHIS).

Adequate amount of data on “similar” patients (in terms of age, weight, treatment type and factor degradation rate) is needed in order to obtain high-quality pharmacokinetic outcomes. Due to the prevalence of haemophilia, this was hard to achieve in the Czech Republic only; data centralisation was therefore in the interest of both physicians and patients.

Collecting data on patients with congenital coagulation disorders, analysis of these data, presentation and publication of results, developing a tool for pharmacokinetic testing of patients as part of the CNHP registry.

The diagnosis of diabetic macular oedema (DMO) is a complication of diabetic retinopathy (ocular complication of diabetes). The project involved the development and running of an electronic database for the collection of data on patients treated with anti-VEGF medicines.

Cancer screening programmes can contribute significantly to decreasing the population burden of cancer. However, such programmes are only effective if they are properly organised. The aim of the project was to maintain and to develop further the system for data collection and for quality control of cancer screening programmes.

Verifying the benefit of a multidisciplinary team-based approach in the comprehensive treatment of patients with liver metastases of colorectal cancer, evaluating the results in defined groups of patients according to selected parameters.

The project objectives were to verify the hypothesis that individuals with a higher cardiovascular risk and diabetic patients are at a higher risk of developing colorectal neoplasia, to identify and to select these individuals for colonoscopy, which should subsequently verify the hypothesis that targeted screening is effective in this group of patients, and finally to verify the feasibility, effectiveness and safety of targeted screening.

This multicentre prospective study was focused on the comparison of detection of polyps and carcinomas during colon capsule endoscopy compared to conventional colonoscopy in individuals with an average risk of colorectal cancer.

Making extensive, extraordinarily valuable data from Czech health registries accessible to a wide range of users – not only for research and publications, but also as a background for economic planning and decision-making.

The National Set of Clinical Standards and Healthcare Indicators was developed with the aim to create a nationwide and standardised tool for further improvements in healthcare quality, which would be based on scientifically established clinical recommendations, the effect of which can be measured using specific quality indicators.

Prognosis establishment is a crucial point for the optimisation of acute heart failure (AHF) management. The aim of the project was to evaluate the most important non-invasive prognostic parameters and to create a model combining these parameters in order to identify patients at risk of an unfavourable development of the condition.

The aim of this project was to identify whether there was a change in response to stroke symptoms in the Czech Republic following the two-year media campaign as compared to previously collected data from 2005. The secondary goal was to identify the predictors of such change in response to stroke symptoms and what prompted people to call 911.

The project was mainly oriented on testing of correlation between quantity and quality (size) of free foetal NA in maternal plasma during pregnancy at pathologies and normal controls. Data from analysis of STR loci, SNPs and gonosomal sequences were evaluated.

The main objective of this project was a complex approach to the research of interactions among chemical compounds present in environmental compartments and their biological effects: study of the fate of mainly persistent chemical compounds in the environment, their effects on the environment and living organisms including humans.