“The Basket of Baskets (BoB) study is the spearhead Program of the Cancer Core Europe (CCE) (Eggermont et al., 2014). Its overall goal is to evaluate the antitumour activity of matched therapies in small CCE patient populations molecularly selected using a novel study design in an international multicentre (basket) approach.”

Translational cancer research covers the whole cancer research continuum from basic to preclinical to early clinical, late clinical and outcomes research. Basic-preclinical research is the "engine" for early clinical research bridging the early translational research gap.

By combining innovative prevention and treatment strategies in a sustainable state‐of‐the‐art virtual European cancer centre/infrastructure, it will be possible by 2030 to achieve a long‐term survival of 3 out of 4 cancer patients in countries with well‐developed healthcare systems.

Effective treatment of cancer remains one of the biggest medical challenges in the world, due to the large diversity in the spectrum of mutations in individual cancer patients. To tackle this problem, cancer research will need to be performed at a larger scale than is currently possible within single cancer institutes.