The molecular basis for water taste in Drosophila.

Sensory detection of water has eluded sensory neurobiologists until recently. The authors show that the Deg/ENaC protein pickpocket28 (ppk28) appears to be expressed in water-sensing neurons in taste bristles of Drosophila.

Using electrophysiology and flies expressing the calcium sensor GCaMP in ppk28 cells, Cameron et al. show that these cells respond to water. Water responses were blunted when other prototypic taste compounds...

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