Abstract

The deleterious effects of large doses of vitamin D, although well established, have not received sufficient emphasis in the therapy of those chronic conditions, notably arthritis, for which prolonged administration of the drug has been suggested.

Danowski, Winkler, and Peters1 reported two patients suffering from vitamin D intoxication, one of whom was taking vitamin D produced by the electrical activation of heat vaporized ergosterol. In both instances there was evidence of decreased renal function, and one patient exhibited soft tissue calcification. Freeman, Rhoads, and Yeager2 described toxic symptoms due to hypervitaminosis D in two subjects taking Ertron. The important symptoms