Set a century in the future, the hero of Spider-Man 2099 was Miguel O'Hara, a Latino who works for Alchemax, a drug company with corrupt board members. O'Hara winds up the guinea pig in a risky genetic experiment and gets his DNA spliced with the genes of a Spider. Now infused with superpowers, he dons a costume based on the 'Day of the Dead' Mexican holiday. More than just another guy in a spider costume, O'Hara's DNA has been genetically altered -- he has venom glands and sharp fangs.