Target details

Target details

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Alternative Name

FA2H

Background

FA2H is a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups.Synonyms: Fatty acid alpha-hydroxylase, Fatty acid 2-hydroxylase,FAAH, FA2H