Organic Mechanisms - Reactions, Stereochemistry and Synthesis

Organic Reactions · Stereochemistry · Modern Synthetic Methods is aimed at
those who desire to learn organic chemistry through an approach that is facile
to understand and easily committed to memory. Throughout the book fundamental
and advanced reaction mechanisms are presented with meticulous precision. The
systematic use of red "electron-pushing arrows" allows students to follow each
transformation elementary step by elementary step. Mechanisms are not only
presented in the traditional contexts of rate laws and substituent effects but,
whenever possible, are illustrated using practical, useful and state-of-the-art
reactions. The abundance of stereoselective reactions included in the treatise
makes the reader familiar with key concepts of stereochemistry.

The fundamental topics of the book address the needs of upper-level
undergraduate students, while its advanced sections are intended for
graduate-level audiences. Accordingly, this book is an essential learning tool
for students and a unique addition to the reference desk of practicing organic
chemists, who as life-long learners desire to keep abreast of both fundamental
and applied aspects of our science. In addition, it will well serve ambitious
students in chemistry-related fields such as biochemistry, medicinal chemistry
and pharmaceutical chemistry.

Editorial Review

Organic chemistry textbooks are generally aimed either at beginners
or more advanced students. However, Reinhard Brückner’s “Advanced
Organic Chemistry” is a work that can accommodate either undergraduate
or graduate students.

The chapters are organized thematically, and contain sections that
are targeted at both novice as well as more experienced students. The
student working toward a first degree in chemistry can postpone study of
those sections that are identified as advanced work, while the student
pursuing an advanced degree can work through the entire text.

With its focus on reaction mechanisms, the Brückner text serves as an
illustrative supplement to conventional textbooks, while it cannot
replace them. The strengths of "Advanced Organic Chemistry" clearly lie
in its very good explanations of mechanisms, the cleverly chosen
examples (Brückner employs significantly fewer R-groups than other
authors), and the literature citations for further reading.

For some of the mechanisms, such as SN1 and SN2,
the examples are tabulated so that it is easy to recognize which is the
relevant mechanism. The style of "Advanced Organic Chemistry" is
generally engaging, and leads to a ready understanding, even of
problematic chemical relationships.

Brückner is recommended as the resource to turn to when a
supplementary treatment is needed.