..Many of the recommendations are appropriately broad enough to promote the use of clinical judgment in the application of the guidelines...

Multicenter validation of a simplified score to predict massive transfusion in trauma

Bryan A CottonDepartment of Surgery and the Center for Translational Injury Research, The University of Texas Health Science Center, Houston, Texas 77030, USAJ Trauma 69:S33-9. 2010

..Early identification of lethal exsanguination may improve survival in this patient population. The purpose of the current study was to validate a simplified score to predict MT at multiple Level I trauma centers...

..for access? (3) if access is achieved, should intravenous fluids be administered? (4) if fluids are to be administered, which solution is preferred? and (5) if fluids are to be administered, what volume and rate should be infused?..

Damage control resuscitation is associated with a reduction in resuscitation volumes and improvement in survival in 390 damage control laparotomy patients

..This has not been examined independently in women and men. A gender dichotomy in outcome after severe injury is known to exist. This study examined gender-related differences in mortality after high product ratio massive transfusion...

Effect of high product ratio massive transfusion on mortality in blunt and penetrating trauma patients

..Therefore, we hypothesized that patients with elevated International Normalized Ratio (INR) on arrival to the hospital may benefit more from transfusion with a high ratio of FFP:PRBC than those with a lower INR...

..The purpose of this study was to validate previously described MT scoring systems and compare these to a simplified nonlaboratory dependent scoring system (Assessment of Blood Consumption [ABC] score)...

Predefined massive transfusion protocols are associated with a reduction in organ failure and postinjury complications

..The purpose of this study was to evaluate the ability of uncrossmatched transfusions in the emergency department (ED) to predict early (< 6 hr) massive transfusion (MT) of red blood cells (RBCs) and blood components...

..Timely diagnosis and treatment of adrenal insufficiency (AI) dramatically reduces mortality in trauma patients. We sought to identify risk factors and populations with a high risk of developing AI...

..The purpose of this study was to determine the utility of clinical and laboratory data for predicting the risk for IAI...

Primary skin closure after damage control laparotomy

M J PommereningDepartment of Surgery, University of Texas Medical School at Houston, Houston, Texas, USA Center for Translational Injury Research, University of Texas Medical School at Houston, Houston, Texas, USA Center for Surgical Trials and Evidence Based Practice, University of Texas Medical School at Houston, Houston, Texas, USABr J Surg 102:67-75. 2015

..Surgical-site infection (SSI) also carries potential morbidity, increased costs and prolonged hospital stay. The aim of this study was to determine whether primary skin closure after DCL increases the risk of SSI...