With the Kardashians, it's not always easy separating fact from reality show fiction.

One thing that's absolutely bonafide? Khloe Kardashian's fertility problems. "Khloe is having major problems getting pregnant," a pal tells the new Us Weekly. Her struggle to conceive with hubby Lamar Odom is "very, very real," the friend adds. "It's not contrived for their reality show."