If you are pregnant, breastfeeding or are taking antidepressant medication, consult your physician before using this product. Take this product under medical supervision if you have bipolar disorder. In a small percentage of people, this product may cause nausea, which tends to subside with long-term use.

Source Naturals SAMe Description

Source Naturals® SAMe is a stable, bioavailable form of S-adenosyl-L-methionine. These tablets are enteric coated and blister packed to prevent breakdown and inactivation of the ingredients.

Dozens of clinical studies have demonstrated that SAMe supports joint comfort, function and mobility in the spine, hips and knees. It is important to the joints because of its critical role in cartilage formation. SAMe helps to form proteoglycans, which are used to renew the matrix of cartilage.

Studies also show that SAMe helps support a positive outlook. It is able to cross the blood-brain barrier where it affects the synthesis and activation of various proteins, such as neurotransmitters. SAMe also plays a role in transmethylation. Transmethylation reactions affect the synthesis, activation, and metabolism of various biological molecules. Some compounds that SAMe methylates are phospholipids. This is a fundamental step in the mediation of cell to cell communication.

SAMe is present in every living cell in the body and plays an important part in many critical cellular functions. However, levels of SAMe tend to decline with age.

Directions

Two tablets, one to three times daily, or as recommend by your health care professional. Take tablets on an empty stomach.

It does what it says, but......
This product works great to help keep me calm - It works almost immediately - I've never tried anything that works so well. However, after taking it for a week I developed really bad stomach cramps. I stopped taking it for a while and the sxs went away. Tried again and the cramping came back. I'm going to try taking 1/2 of a pill and see what that does. The product works so well that I hate to give it up but I can't tolerate the stomach pain.
January 31, 2009

Cost is half of what I can purchase it for at the local health food store.
October 7, 2007

Effective and low priced SAMe
Very good quality for the price.
May 9, 2007

1-5of5

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Source Naturals® SAMe is a stable, bioavailable form of S-adenosyl-L-methionine. These tablets are enteric coated and blister packed to prevent breakdown and inactivation of the ingredients.

Dozens of clinical studies have demonstrated that SAMe supports joint comfort, function and mobility in the spine, hips and knees. It is important to the joints because of its critical role in cartilage formation. SAMe helps to form proteoglycans, which are used to renew the matrix of cartilage.

Studies also show that SAMe helps support a positive outlook. It is able to cross the blood-brain barrier where it affects the synthesis and activation of various proteins, such as neurotransmitters. SAMe also plays a role in transmethylation. Transmethylation reactions affect the synthesis, activation, and metabolism of various biological molecules. Some compounds that SAMe methylates are phospholipids. This is a fundamental step in the mediation of cell to cell communication.

SAMe is present in every living cell in the body and plays an important part in many critical cellular functions. However, levels of SAMe tend to decline with age.

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