Device, System And Method For Determining The Effect Of Photodynamic Or Photothermal Tumor Therapy - A device and method for determining the effect of therapy in a tumour tissue of a human or a mammal under interstitial photodynamic or photothermal therapy by analyzing a liquid flow in a tissue of a human or a mammal. A first fibre is interstitially inserted in a first position of said tissue and connected to a light source, and a second fibre is interstitially inserted in a second position of said tissue for receiving light emitted from the first fibre. A detector is arranged for receiving the light from said second fibre for producing an output signal. An analysator receives the output signal from the detector and determines if there is a frequency component in the frequency area below about 1 MHz in the output signal, which is indicative of blood cell movement in the tissue. If the frequency component is below a threshold value, it is determined that there is no blood flow. In photothermal therapy, no blood flow is interpreted as the fact that the blood has coagulated and the therapy may be finalized. In photodynamic tumour therapy, changes in blood flow may be used to evaluate the treatment progression.

04-16-2009

20090118646

Human Cavity Gas Measurement Device And Method - A device and method for gas measurements in body cavities are provided. These may be any body cavity containing a free gas, where there is an interest in detecting and/or measuring the concentration of said free gas by means of a non-invasive or minimally invasive method. According to an exemplary embodiment measurement of free oxygen in cranium cavities is performed by scattering media absorption spectroscopy, and in particular variations of such oxygen. This is particularly useful for diagnostic purposes based on the measurements, for instance for detecting sinusitis or the like.

05-07-2009

20100185099

SYSTEM AND METHOD FOR THERAPY AND DIAGNOSIS COMPRISING IN COMBINATION NON-MECHANICAL AND MECHANICAL DISTRIBUTORS FOR DISTRIBUTION OF RADIATION - A system and method for therapy and diagnosis of a human or animal. At least one coupling element for coupling of radiation couples radiation from at least a first radiation source to a tumor site and/or from said second radiation source to said site and/or from said site to a detector. The coupling elements are combinations of at least one translatory distributor, at least one rotary distributor, and at least one operation mode selector means for directing either said therapeutic radiation or said diagnostic radiation to said site through said at least one first radiation conductor. The system may be used for interactive interstitial photodynamic tumor therapy. The system and method according to the invention combines the advantages of purely mechanical and purely non-mechanical solutions in a new and synergetic way.

07-22-2010

20110034971

SYSTEM AND METHOD FOR CONTROLLING AND ADJUSTING INTERSTITIAL PHOTODYNAMIC LIGHT THERAPY PARAMETERS - A method and system for controlling and adjusting light in interstitial photodynamic light therapy (IPDT) in a subject is disclosed. More particularly, a method for controlling the light in interstitial tumor photodynamic light therapy is described using calculation method for determination of status of tissue during the PDT treatment. The status is used in a feedback loop to control the continued PDT treatment. Methods are disclosed that constitute pre-treatment and realtime dosimetry modules for IPDT on the whole prostate glandular tissue. The method includes reconstruction of the target geometry, optimization of source fiber positions within this geometry, monitoring of the light attenuation during the treatment procedure and updating individual fiber irradiation times to take into account any variation in tissue light transmission. A control device that is arranged to restrict delivery of therapeutic light treatment at least temporary in dependence of at least one attribute of one of photodynamic treatment parameters. In comparison to no treatment feedback, a significant undertreatment of the patient as well as damage to healthy organs at risk are avoided.

02-10-2011

20120140229

Apparatus And Method For Non-Intrusive Assessment Of Gas In Packages - A method and apparatus are disclosed for assessment of a sealed package. Light is emitted from a narrow-band laser source towards said package from outside of said package. An absorption signal of said light scattered in said package is measured, wherein said absorption is caused by said at least one gas when said light is scattered and travels in said sealed package. Measuring is made outside of said package, whereby said assessment is non-intrusive with regard to said package. It is determined if a deviation exists from a predetermined, expected gas composition and/or concentration of said at least one gas within said sealed package based on said measured absorption signal. Thus sealing of said package for said gas is detected.

06-07-2012

20140125970

Apparatus And Method For Non-Intrusive Assessment Of Gas In Packages - A method and apparatus are disclosed for assessment of a sealed package. Light is emitted from a narrow-band laser source towards said package from outside of said package. An absorption signal of said light scattered in said package is measured, wherein said absorption is caused by said at least one gas when said light is scattered and travels in said sealed package. Measuring is made outside of said package, whereby said assessment is non-intrusive with regard to said package. It is determined if a deviation exists from a predetermined, expected gas composition and/or concentration of said at least one gas within said sealed package based on said measured absorption signal. Thus sealing of said package for said gas is detected.

05-08-2014

20160123931

Apparatus And Method For Non-Intrusive Assessment Of Gas In Packages - A method and apparatus are disclosed for assessment of a sealed package. Light is emitted from a narrow-band laser source towards said package from outside of said package. An absorption signal of said light scattered in said package is measured, wherein said absorption is caused by said at least one gas when said light is scattered and travels in said sealed package. Measuring is made outside of said package, whereby said assessment is non-intrusive with regard to said package. It is determined if a deviation exists from a predetermined, expected gas composition and/or concentration of said at least one gas within said sealed package based on said measured absorption signal. Thus sealing of said package for said gas is detected.