Valneva's Lyme disease vaccine candidate - VLA15

Lyme disease is the most common vector-borne illness in the Northern Hemisphere. Valneva's candidate is the only vaccine in clinical development worldwide.

Valneva reported positive Phase 1 interim data for its Lyme disease vaccine candidate VLA15 (Press release). The Company has successfully concluded the end of Phase 1 process for this candidate with the Food and Drug Administration (FDA) and has obtained alignment with regard to its Phase 2 strategy (Press release). In December 2018, Valneva announced the initiation of the Phase 2 clinical development (Press Release).

Valneva´s vaccine candidate VLA15, under Fast Track Designation by the FDA, is a multivalent vaccine that targets the outer surface protein A (OspA) of Borrelia. Pre-clinical data showed that VLA15 has the potential for protection against the majority of Borrelia species pathogenic for humans (Source).

The global market for a vaccine against Lyme disease is currently estimated at approximately €700 - €800 million annually1.