How to use Plenvu for colonoscopy bowel preparation

Plenvu is the first 1 liter PEG-based bowel cleansing agent. Plenvu can be used alone or in conjunction with over the counter laxatives like bisacodyl or magnesium citrate. If an over the counter laxative is also recommended by your physician, it is usually used about 1 hour before the bowel cleansing agent. There are 2 main ways to take your bowel cleansing agent: the day before regimen or the split dose regimen.

If you have diabetes mellitus, you may need to take half the dose of your medication while on clear liquid diet. Please, talk to your provider about this.

Open the carton and remove the dose 1 sachet.

Pour the contents of dose 1 into a measuring container that can hold 500 ml of fluid.

Add water to make up to 500 ml and stir until all the powder has dissolved. This may take up to approximately 8 minutes.

Drink the 500 ml Plenvu dose 1 solution over 30 minutes by drinking 1 glassful every 10 to 15 minutes. This should be done in the afternoon or early evening before the colonoscopy (e.g., 4:00 to 6:00 PM).

Following the Plenvu dose, drink a further 500 ml of clear fluid over a further 30 minutes.

If severe bloating, distention, or abdominal pain occurs, following the first dose, delay the second dose until the symptoms resolve.

Dose 2 – Approximately 6 hours later in the evening the night before the colonoscopy (e.g., 10:00 PM to 12:00 AM):Take the second dose of Plenvu.

Pour the contents of dose 2 into a measuring container that can hold 500 ml of fluid.

Add water to make up to 500 ml and stir until all the powder has dissolved. This may take up to approximately 8 minutes.

If you have diabetes mellitus, you may need to take half the dose of your medication while on clear liquid diet. Please, talk to your provider about this.

Take 4 tablets of bisacodyl (Dulcolax) around 3:00-4:00 PM.

Open the carton and remove the dose 1 sachet.

Pour the contents of dose 1 into a measuring container that can hold 500 ml of fluid.

Add water to make up to 500 ml and stir until all the powder has dissolved. This may take up to approximately 8 minutes.

Drink the 500 ml Plenvu dose 1 solution over 30 minutes by drinking 1 glassful every 10 to 15 minutes. This should be done in the afternoon or early evening before the colonoscopy (e.g., 4:00 to 6:00 PM).

Following the Plenvu dose, drink a further 500 ml of clear fluid over a further 30 minutes.

If severe bloating, distention, or abdominal pain occurs, following the first dose, delay the second dose until the symptoms resolve.

Dose 2 – Approximately 6 hours later in the evening the night before the colonoscopy (e.g., 10:00 PM to 12:00 AM):Take the second dose of Plenvu.

Pour the contents of dose 2 into a measuring container that can hold 500 ml of fluid.

Add water to make up to 500 ml and stir until all the powder has dissolved. This may take up to approximately 8 minutes.