(1) Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, Maryland, USA; (2) Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, USA; (3) Present address: Center for Scientific Review, National Institutes of Health, Bethesda, Maryland, USA; (4) Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA; (5) Department of Physiology, University of Maryland School of Medicine, Baltimore, Maryland, USA; (6) Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA