COMBINATION TREATMENT OF CANCER
The present technology relates to a method of treating cancer by sensitizing human tumours to DNA damaging therapies through activating FBXO32 expression. Transactivation of FBXO32 through the...

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US20120214677

LUCIFERASE BIOSENSOR
A modified beetle luciferase protein which is an environmentally sensitive reporter protein is provided.

CONSTRUCT SYSTEM AND USES THEREFOR
The present invention discloses construct systems and methods for comparing different iso-accepting codons according to their preference for translating RNA transcripts into proteins in cell or...

METHODS AND KITS FOR DIAGNOSING COLORECTAL CANCER
The invention pertains to a method for early detection and screening of colorectal cancer in human subjects based on RNA isolated from blood obtained from said subject. According to the invention,...

GRADING OF BREAST CANCER
Methods and compositions for the identification of breast cancer grade signatures are provided. The signature profiles are identified based upon multiple sampling of reference breast tissue...

HUMAN PARVOVIRUS: HUMINK PARVOVIRUS
Provided herein are sequences of the genomes and encoded proteins of a new human parvovirus, Humink parvovirus, and variants thereof. Also provided are methods of detecting the Humink parvovirus...

Cathepsin E as a Marker of Colon Cancer
Elevated levels of cathepsin E (catE) are demonstrated to be diagnostic of intestinal forms of cancer, such as colorectal cancer. Elevated levels of cathepsin E (catE, monomeric forms) are...

SUMOYLATION OF SERCA2a AND CARDIOVASCULAR DISEASE
Methods for treating cardiovascular disease, and in particular heart failure, are provided comprising administering a therapeutically effective amount of a modulator of SERCA2a post-translation...

MOLECULAR DIAGNOSTICS REAGENTS AND METHODS
The present invention relates to automated devices and methods for the extraction of nucleic acids from cells, the amplification of segments of nucleic acid and the detection of nucleic acids, all...

Storage of genetic information
Methods for the long-term storage of hereditary information such as DNA are described herein. In some instances, lyophilized DNA and sugar is introduced into a hermetically sealed vial. Kits for...