Project: Identification and study of differentially expressed genes in neuroblastoma.

project duration

01-JAN-00 – 31-DEC-03

abstract

This project aims at the identification and characterization of genes involved in neuroblastoma. After isolation of differentially expressed transcripts using suppression subtractive hybridization, the differential expression status of the identified clones will be verified with quantitative PCR. We will compare the expression profile between the various genetic subgroups of neuroblastoma tumors and cell lines and the normal precursus cells in the embryonic adrenals.