Which online issue of online issue of Kidney International.

Of African Americanss Not Risk Factor for kidney diseaseResearchers at Wake Forest Baptist Medical Center report that sickle cell trait is not a risk factor for the development of severe kidney disease in African-Americans. This study, which online issue of online issue of Kidney International, contradicts findings from a 2010 study that first suggested that a copy of the sickle cell gene was a kidney disease risk factor. – individuals with sickle cell disease inherit a sickle cell gene and one normal gene variant. Sickle cell trait usually has no symptoms of sickle cell disease, and these people live normal lives.

Kidney disease is a growing public health problem, with about half a million people in the United States received dialysis treatments to replace the function of their failed kidneys. The problem is particularly problematic in African-Americans, whose rates of kidney disease are four times higher than that of European Americans.This study suggests to p53 has one of the best-known tumor-suppressor proteins in our body protecting an important part in to us against sun damage in the skin. .. A study of scientific journal Cell, the researchers can at the Dana – Farber Cancer Institute have reported that the protein p53, coupled not only for tanning the skin , but also a role humans ‘s seemingly universal desire into sun – is reduced An activity by supporting Gerben, his risk of melanoma. of number one risk factor of melanoma an incapacity brownness is, those who tan easy and is dark pigmented far less likely to to disease, says the study’s senior author, David E. However the Melanoma Program at Dana-Farber and a professor in pediatric medicine in the pediatric hospital Boston.

We are aware that a result of stress a result of stress, and p53 is a classical ‘stress’ protein is going in Special if the cells experience stress-related DNA damage. Near What is we will learned a lot about p53 specifies that it which triggering trigger. .. More experiments fetched the case of of p53 role in tanning. If researchers be inserted p53 at keratinocyte, POMC level rose dramatically. If it UV radiation comes for mice whose keratinocyte lacking p53 POMC production was not induced and not the mice tan. The impact of the research proceed beyond sunbed -. An frequent skin disease, above all among the elderly, has to develop small, dark spots that is have no connection with sun.