microRNA Diagnostics and Therapeutics

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Open Access

Abstract

microRNAs (miRNAs) are a class of non-coding
RNA which suppress target gene expression. miRNAs are
involved in most physiological and pathological process,
including carcinogenesis. miRNA expression profiles help to
improve lung cancer diagnosis, classification and prognostic
information. Tumor suppressive and oncogenic miRNAs have
been discovered and their functions have been investigated.
Emphasis is placed on the development of miRNA-based
methods for lung cancer diagnosis and therapy and future
directions are proposed.

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