Zhang, CT

Andrew Zhang, New Haven, CT US

Patent application number

Description

Published

20110201563

CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS - The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.

08-18-2011

20120034295

CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS - The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.

02-09-2012

Biao Zhang, West Hartford, CT US

Patent application number

Description

Published

20130147944

VISION-GUIDED ALIGNMENT SYSTEM AND METHOD - A vision-guided alignment system to align a plurality of components includes a robotic gripper configured to move one component relative to another component and a camera coupled to a processor that generates an image of the components. A simulated robotic work cell generated by the processor calculates initial calibration positions that define the movement of the robotic gripper such that position errors between the actual position of the robotic gripper and the calibration positions are compensated by a camera space manipulation based control algorithm executed by the processor to control the robotic gripper to move one component into alignment with another component based on the image of the components.

06-13-2013

20140156073

TELEOPERATED INDUSTRIAL ROBOTS - A teleoperated robot system has a watchdog to determine if the rate of data transmission from a computing device such as a robot controller located in the station used by the operator of the teleoperated robot to the remotely located industrial robot has fallen below a minimum data rate or the time for transmission of data has exceeded a maximum time. Upon the occurrence of either or both of the foregoing, one or more types of corrective action are undertaken to bring the teleoperated robot and the processes performed by the robot.

06-05-2014

20150298318

Teleoperation Of Machines Having At Least One Actuated Mechanism - A machine that has at least one actuated mechanism is remotely located from a control station. A two way real-time communication link connects the machine location with the control station. An interface at the control station allows an operator to select one or more virtual constraints on operation of the machine when the machine is performing a predetermined function. The virtual constraints are transmitted over the two way real-time communication link to the machine location. The machine has predetermined safety limits that are stored in a controlling device at the machine location. The stored predetermined safety limits are extracted and automatically mapped to the control station using the two way real-time communication link. The controlling device maps the predetermined safety limits to the virtual constraints.

10-22-2015

20150314447

Teleoperation Of Machines Having At Least One Actuated Mechanism And A Fault Detection And Recovery System - A machine has at least one actuated mechanism is remotely located from a control station. A two way real-time communication link connects the machine location with the control station. A controller at the machine location has program code that is configured to determine from data from one or more sensors at the machine location if an actual fault has occurred in the machine when the machine is performing its predetermined function and to determine for an actual fault one or more types for the fault and transmit the one or more fault types to the control station for analysis. The code in the controller is configured to be a preprogrammed trap routine specific to the machine function that is automatically executed when an error in machine operation is detected at the machine location. The controller also has a default trap routine that is executed when specific routine does not exist.

DEVICE AND METHOD FOR TRANSFORMER IN-SITU INSPECTION - An inspection device for use in a fluid container having at least an opening includes a housing sized to fit through the opening. The housing has at least two fluid flow channels extending therethrough, each having an inlet and an outlet, and a pump maintained in the housing within each fluid flow channel. The pumps are selectively controlled to maneuver the housing within the fluid container. The inspection device continues with a method of in-situ inspection of a container having at least one opening to receive a fluid, that includes up-loading a virtual model of the container into a computer, inserting the device into the container, generating a position signal by the device and receiving the position signal on a computer. A virtual image of the device in the virtual model of the container is generated to determine an actual position of the device within the container.

PYRIMIDOTHIENOINDAZOLES - The invention relates to novel pyrimidothienoindazoles of formula (I), processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders.

NOVEL HETEROCYCLES - The invention relates to novel heterocycles of formula (I) processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders.

07-14-2011

Patent applications by Chengzhi Zhang, Orange, CT US

Don Zhang, Branford, CT US

Patent application number

Description

Published

20110182882

Icotinib Hydrochloride, Synthesis, Crystalline Forms, Pharmaceutical Compositions, and Uses Thereof - The invention relates to 4-[(3-ethynylphenyl)amino]-6,7-benzo-12-crown-quinazoline hydrochloride, its new crystalline forms, its therapeutic usage for treatment of diseases mediated by EGFR kinase and its combinatory therapeutic usage together with other therapeutic agents. The invention also provides synthetic methods for preparation of 4-[(3-ethynylphenyl)amino]-6,7-benzo-12-crown-quinazoline hydrochloride, its new crystalline forms, and the relevant synthetic intermediates for synthesis of 4-[(3-ethynylphenyl)amino]-6,7-benzo-12-crown-quinazoline hydrochloride.

07-28-2011

20120258995

New Indolinone Protein Kinase Inhibitors - The present invention relates to new indolinone compounds and their pharmaceutically acceptable salts and prodrugs for treating and preventing VEGFR related cellular disorders such as cancer.

10-11-2012

George Zhang, Windsor, CT US

Patent application number

Description

Published

20090125146

Method of and Apparatus for Automated Path Learning - A robot having a force sensor and a tool fixture for operating on a workpiece that may have a complex surface contour is programmed by an operator first teaching the robot by a suitable technique such as lead through teaching a few gross points of the contour. These points, known as guiding points, are used to generate a program to be followed by the robot under the control of the robot controller and using force control during which the robot finalizes the guiding points and teaches one or more points on the contour intermediate adjacent guiding points. The controller or other computing device uses the points so taught to generate the path the robot tool fixture will follow when the tool is to operate on the workpiece.

05-14-2009

20100145509

Method And System For In-Production Optimization of The Parameters Of A Robot Used for Assembly - A robot is used to repeatedly assemble part during a continuous production run of parts to be assembled. There are parameters of the robot associated with the assembly. These parameters are used to assemble the parts. Simultaneously with that repeated assembly the robot parameters are optimized. The parts to be assembled have a starting position for the assembly and the simultaneous optimization of the robot assembly parameters also includes the learning of the starting position. The robot assembly parameters can be optimized in a predefined manner. The optimized parameters can then be verified and the optimized and verified robot assembly parameters may then be used in place of the parameters of the robot associated with the parts assembly along with the learned starting position.

06-10-2010

20100211204

METHOD AND SYSTEM FOR ROBOTIC ASSEMBLY PARAMETER OPTIMIZATION - A method and system to optimize the parameters of a robot used in an assembly process. The assembly process is categorized based on its nature which may be cylindrical, radial and multi-stage insertion. The search pattern and search parameters are specified. The parameters are optimized and the optimized parameter set are verified and when a predetermined criteria such as assembly cycle time set and/or success rate is met the optimization process stops. When the optimization stops the verified parameters are used to cause the robot to perform the categorized assembly process. If the parameters do not meet the predetermined criteria, another round of optimization using the same or other parameters can be performed.

08-19-2010

20120036692

METHOD AND APPARATUS FOR ENGINE PISTON INSTALLATION BY USE OF INDUSTRIAL ROBOTS - A method and apparatus for engine piston installation in which robots are used for the entire engine piston installation process. A first robot equipped with a stuffing gripper and force control picks up a piston with a connection rod, detects the piston ring presence, squeezes the rings, finds the engine cylinder bore, and stuffs the piston into the cylinder bore. A second robot can be used to load and unload the engine block, hold the block and position it to the location, and indexes the crankshaft into the proper orientation for each cylinder bore. A set of tools either fixed on a stationary station or on a third robot is used to guide the piston connecting rod, transport and place on the connecting rod cap, and fasten the cap onto the connecting rod. The piston connecting rod guiding process may be omitted in piston stuffing for some types of engines.

02-16-2012

20130175206

BATTERIES TESTING AND SORTING SYSTEM AND THE METHOD THEREOF - A system includes a robot, comprising a manipulator and a controller, with a gripper mounted on the manipulator, for picking the battery for testing and sorting, a battery holding section for receiving batteries for testing and sorting at predetermined locations in the battery holding section, and a testing section disposed within the working range of the robot, for testing an electrical condition of the battery for testing and sorting, whereby the controller controls the manipulator and the gripper to first-pick the battery for testing and sorting at the predetermined location from the battery holding section and place it to contact the testing section for testing, the testing section tests the battery and sends to the controller a signal indicating the electrical condition of the tested battery, and the controller controls the manipulator and the gripper to second-pick the battery contacting the testing section and sort it according to the signal.

07-11-2013

20140144871

Stripping Structure And Method For Removing Enamel Insulation From Lead Ends - Stripping structure strips insulation from ends of a plurality of leads of a lead bundle. Each lead includes a conductor member coated with the insulation. The structure includes a housing having wall structure defining a stripping chamber, an inlet in fluid communication with the stripping chamber, and an outlet in fluid communication with the stripping chamber. A cover has an opening for receiving an end of the lead bundle in a sealing manner so that the leads thereof are received in the stripping chamber. Chemical stripping solution is in communication with the inlet. When the lead bundle is received through the opening with the leads in the stripping chamber and when the chemical stripping solution is provided though inlet and in the stripping chamber, the chemical stripping solution strips the insulation from the conductor members, with the stripping solution along with stripped insulation exiting through the outlet.

05-29-2014

20150217452

METHOD AND SYSTEM FOR ROBOTIC ASSEMBLY PARAMETER OPTIMIZATION - A method and system to optimize the parameters of a robot used in an assembly process. The assembly process is categorized based on its nature which may be cylindrical, radial and multi-stage insertion. The search pattern and search parameters are specified. The parameters are optimized and the optimized parameter set are verified and when a predetermined criteria such as assembly cycle time set and/or success rate is met the optimization process stops. When the optimization stops the verified parameters are used to cause the robot to perform the categorized assembly process. If the parameters do not meet the predetermined criteria, another round of optimization using the same or other parameters can be performed.

08-06-2015

20150217453

METHOD AND SYSTEM FOR ROBOTIC ASSEMBLY PARAMETER OPTIMIZATION - A method and system to optimize the parameters of a robot used in an assembly process. The assembly process is categorized based on its nature which may be cylindrical, radial and multi-stage insertion. The search pattern and search parameters are specified. The parameters are optimized and the optimized parameter set are verified and when a predetermined criteria such as assembly cycle time set and/or success rate is met the optimization process stops. When the optimization stops the verified parameters are used to cause the robot to perform the categorized assembly process. If the parameters do not meet the predetermined criteria, another round of optimization using the same or other parameters can be performed.

08-06-2015

20150369751

DEVICE AND METHOD FOR TRANSFORMER IN-SITU INSPECTION - An inspection device for use in a fluid container having at least an opening includes a housing sized to fit through the opening. The housing has at least two fluid flow channels extending therethrough, each having an inlet and an outlet, and a pump maintained in the housing within each fluid flow channel. The pumps are selectively controlled to maneuver the housing within the fluid container. The inspection device continues with a method of in-situ inspection of a container having at least one opening to receive a fluid, that includes up-loading a virtual model of the container into a computer, inserting the device into the container, generating a position signal by the device and receiving the position signal on a computer. A virtual image of the device in the virtual model of the container is generated to determine an actual position of the device within the container.

12-24-2015

Patent applications by George Zhang, Windsor, CT US

George Q. Zhang, Windsor, CT US

Patent application number

Description

Published

20140121828

ULTRA-FLEXIBLE PRODUCTION MANUFACTURING - A manufacturing system has one or more work cells that each performs one or more manufacturing processes. The system also has one or more mobile transport units (“MTUs”) that deliver transportable containers containing workpieces to and from said work cells. The MTUs deliver the containers to the work cells in a manner such that the workpieces are localized in the work cells. The manufacturing system also has a computer system that has status information for each of the one or more MTUs and uses the status information to control each of the one or more MTUs to deliver the transportable containers to and from the one or more work cells.

05-01-2014

20140156073

TELEOPERATED INDUSTRIAL ROBOTS - A teleoperated robot system has a watchdog to determine if the rate of data transmission from a computing device such as a robot controller located in the station used by the operator of the teleoperated robot to the remotely located industrial robot has fallen below a minimum data rate or the time for transmission of data has exceeded a maximum time. Upon the occurrence of either or both of the foregoing, one or more types of corrective action are undertaken to bring the teleoperated robot and the processes performed by the robot.

06-05-2014

20150233787

AIR GAP CRAWLER INSTALLATION DEVICE - A device for installing a modular crawler into an air gap of rotating electrical machinery and removing the crawler from the air gap has a reconfigurable handle attached to a curved head made from metallic material. The crawler is magnetically attached to the curved head when it is desired to insert the crawler into the air gap or remove the crawler from the air gap. The head can be rolled in the field into the curvature needed to match the stator's inner surface so that the installation device can easily be inserted in the air gap. The handle has several joints that can be adjusted in the field as needed for the best reachability. A camera is mounted on the curved head so that an operator can see the interface region between the curved head, crawler and air gap.

08-20-2015

20150298318

Teleoperation Of Machines Having At Least One Actuated Mechanism - A machine that has at least one actuated mechanism is remotely located from a control station. A two way real-time communication link connects the machine location with the control station. An interface at the control station allows an operator to select one or more virtual constraints on operation of the machine when the machine is performing a predetermined function. The virtual constraints are transmitted over the two way real-time communication link to the machine location. The machine has predetermined safety limits that are stored in a controlling device at the machine location. The stored predetermined safety limits are extracted and automatically mapped to the control station using the two way real-time communication link. The controlling device maps the predetermined safety limits to the virtual constraints.

10-22-2015

20150314447

Teleoperation Of Machines Having At Least One Actuated Mechanism And A Fault Detection And Recovery System - A machine has at least one actuated mechanism is remotely located from a control station. A two way real-time communication link connects the machine location with the control station. A controller at the machine location has program code that is configured to determine from data from one or more sensors at the machine location if an actual fault has occurred in the machine when the machine is performing its predetermined function and to determine for an actual fault one or more types for the fault and transmit the one or more fault types to the control station for analysis. The code in the controller is configured to be a preprogrammed trap routine specific to the machine function that is automatically executed when an error in machine operation is detected at the machine location. The controller also has a default trap routine that is executed when specific routine does not exist.

Guoyao Zhang, Stamford, CT US

Patent application number

Description

Published

20140244444

Paperless Ticketing System - A paperless ticketing program acts as an intermediary between existing concrete dispatch and concrete batching programs. The paperless ticketing program receives concrete ticket delivery information from the concrete dispatch program and batch weight information from the concrete batching program in order to create a paperless ticket. A paperless ticketing client runs on a portable computer having a touch screen interface to allow a customer to electronically sign the ticket to acknowledge receipt of a concrete delivery. The paperless ticketing program retrofits existing systems with paperless ticketing functionality.

Huan Zhang, Glastonbury, CT US

Patent application number

Description

Published

20130270043

ELEVATOR SYSTEM BELT - A belt for suspending and/or driving an elevator car includes a plurality of wires arranged into one or more cords and a jacket substantially retaining the one or more cords. Each cord includes a plurality of wires arranged around at least one non load-bearing core. An elevator system includes an elevator car and one or more sheaves. One or more belts are operably connected to the car and interactive with the one or more sheaves for suspending and/or driving the elevator car. Each belt of the one or more belts includes a plurality of wires arranged into one or more cords and a jacket substantially retaining the one or more cords. Each cord includes a plurality of wires arranged around at least one non load-bearing core.

10-17-2013

20130270044

ELEVATOR SUSPENSION AND/OR DRIVING ARRANGEMENT - An elevator system includes an elevator car, one or more sheaves, and one or more belts operably connected to the car and interactive with the one or more sheaves for suspending and/or driving the elevator car. The one or more belts include a plurality of wires arranged into one or more cords, and a jacket substantially retaining the one or more cords. A cord ratio, between a smallest sheave diameter (D) of the one or more sheaves of the elevator system that are interactive with the belt and a largest cord diameter (d

10-17-2013

20140027211

Coated Rope or Belt for Elevator Systems - Elevator coated ropes or belts are disclosed. The coated rope or belt may include at least one cord and a jacket retaining the at least one cord. The cord may include a plurality of filaments. The filaments are free of second-order helical structure. In a first embodiment, the filaments includes at least one inner filament and a plurality of outer filaments surrounding the at least one inner filament. The outer filaments are bunched together by forming a first-order helical structure through the length of the cord. In a second general embodiment, the filaments are free of both first- and second-order helical structures. The filaments are bunched together by a restraining loop or adhesive at one or more locations along the length of the cord. Methods of making the tension cord are also disclosed.

01-30-2014

20140076669

Elevator Tension Member - Elevator tension members are disclosed. The disclosed tension member longitudinally extends along a longitudinal axis and includes a plurality of fibers formed into one or more primary strands or cords extending parallel to the longitudinal axis and a plurality of fibers formed into one or more secondary strands or cords extending parallel to the longitudinal axis and through less than the full length of the belt, and a jacket retaining the primary and secondary strands or cords. The secondary strands or cords have a tensile modulus greater than a tensile modulus of the jacket and less than a tensile modulus of the primary strands or cords. Methods of making the tension member are also disclosed.

03-20-2014

20150375963

ELEVATOR CORD HEALTH MONITORING - A method of fault detection of a belt or rope includes connecting a fault detection unit to at least a portion of a belt or rope including a plurality of wires arranged in a plurality of strands and/or cords. At least the portion of the belt or rope is subjected to an AC voltage of high frequency range and an electrical impedance of the portion of the belt or rope is measured via the fault detection unit. Using at least the measured electrical impedance of the portion of the belt or rope, a fault condition of the belt or rope is determined.

12-31-2015

20160002006

ELEVATOR CORD HEALTH MONITORING - A method of fault detection of a belt or rope includes interconnecting a plurality of cords of the belt or rope, the cords including a plurality of wires, to form a bridge circuit. A fault detection bridge circuit is subjected to a voltage excitation and outputs a voltage which is indicative of the belt or rope damage but remaining insensitive to other environmental noises.

Joanna Hong Zhang, Milford, CT US

Patent application number

Description

Published

20100099766

Topical NSAID compositions having sensate component - Topical analgesic compositions comprising a topically administrable NSAID, a sensate agent and optionally a self-warming system, when administered to a patient in need thereof, provide significant improvements in the rate and extent of skin absorption, as well as impart a sensation of rapid and complete relief from pain.

OXY-FIRED BOILER UNIT AND METHOD OF OPERATING THE SAME - An oxy-combustion boiler unit is disclosed which includes a furnace for combusting fuel and for emitting flue gas resulting from combustion. The furnace has first, second and third combustion zones, and an air separation unit for separating oxygen gas from air and providing a first portion of the separated oxygen to a first oxidant flow, a second portion to a second oxidant flow, and a third portion of the separated oxygen gas to the first, second, and third zones of the furnace. A controller can cause the separated oxygen gas to be distributed so that the first and second oxygen flows have a desired oxygen content, and so that the first, second, and third zones of the furnace receive a desired amount of oxygen based on a combustion zone stoichiometry control.

Lei Zhang, Stamford, CT US

Patent application number

Description

Published

20150225241

PRIMARY AMINE-CONTAINING POLYMERS USEFUL AS SCALE INHIBITORS - Processes for inhibiting scale produced during wet process phosphoric acid production by adding a scale-inhibiting amount of a reagent having a primary amine-containing polymer, or salt thereof, to one or more stages of a wet process phosphoric acid production stream are provided herein, wherein the primary amine-containing polymer includes an A mer according to Formula (I):

08-13-2015

Lingang Zhang, Avon, CT US

Patent application number

Description

Published

20140080126

QUANTIFICATION OF NUCLEIC ACIDS AND PROTEINS USING OLIGONUCLEOTIDE MASS TAGS - The invention provides a method for detecting and quantifying the amount of target molecules, such as nucleic acids or proteins in a sample. The target molecules are first recognized and bounded by target-specific probes, generally nucleic acids or proteins that bind specifically to the targets, each of which is labeled with a short single-stranded nucleic acid probe, either DNA or RNA, with distinct molecular weight. This label is called an oligonucleotide mass tag. One or several standard oligonucleotide sequences can be designed with similar sequence but distinct molecular weight to those oligonucleotide mass tags. Then the oligonucleotide mass tags associated with bounded probes and the standard sequences are co-amplified using a pair of common primers. The presence and/or amount of each oligonucleotide mass tag, which corresponds to the amount of corresponding target molecule, is determined by a primer extension reaction and quantification of the primer extension product.

03-20-2014

20150184233

QUANTIFICATION OF NUCLEIC ACIDS AND PROTEINS USING OLIGONUCLEOTIDE MASS TAGS - The invention provides a method for detecting and quantifying the amount of target molecules, such as nucleic acids or proteins in a sample. The target molecules are first recognized and bounded by target-specific probes, generally nucleic acids or proteins that bind specifically to the targets, each of which is labeled with a short single-stranded nucleic acid probe, either DNA or RNA, with distinct molecular weight. This label is called an oligonucleotide mass tag. One or several standard oligonucleotide sequences can be designed with similar sequence but distinct molecular weight to those oligonucleotide mass tags. Then the oligonucleotide mass tags associated with bounded probes and the standard sequences are co-amplified using a pair of common primers. The presence and/or amount of each oligonucleotide mass tag, which corresponds to the amount of corresponding target molecule, is determined by a primer extension reaction and quantification of the primer extension product.

Naijie Zhang, Ridgefield, CT US

Patent application number

Description

Published

20090071618

HIGH-PERFORMANCE STRENGTH RESINS IN PAPERMAKING INDUSTRIES - A composition comprising a functionalized water-soluble, cationic, thermosetting, cellulose reactive polymer with a doubly structured backbone that is the reaction product of: (a) a copolymerized (i) acrylamide component, (ii) cationic co-monomer component and (iii) at least one multifunctional crosslinking monomer component; and (b) a cellulose reactive agent component; such that the acrylamide component, the cationic co-monomer component, the multifunctional crosslinking monomer component, and the cellulose reactive agent component are in an amount sufficient amount to produce a polymer that imparts strength to a fibrous substrate when the polymer is added to paper stock during a papermaking process. The invention also relates to methods for making and using such a composition.

03-19-2009

20110223256

Method For Stabilizing Flavonoid Aqueous Dispersion - A method for suspending microparticulated water insoluble bioactive compound in a beverage by incorporating solubilized or dispersed microparticulated compound and at least one dispersion stabilizer into a beverage. A composition comprising solubilized or dispersed microparticulated water insoluble bioactive compound and a dispersion stabilizer agent.

Zero Calorie Polyphenol Aqueous Dispersions - A method for stably dispersing microparticulated water insoluble bioactive polyphenol in a beverage by combining the bioactive polyphenol dissolved in an alkaline solution with an aqueous solution of at least one dispersion stabilizer. A composition comprising dispersed microparticulated water insoluble bioactive polyphenol(s) and a dispersion stabilizer.

03-22-2012

20120093899

Process for Preparing a High Stability Microcapsule Product and Method for Using Same - The present invention is directed to a process for preparing a capsule product through the increase in the polymerization cure temperature and cure time during the capsule-making process. The microcapsule products prepared according the process of the present invention exhibit enhanced retention of active materials in consumer products which promote instability.

04-19-2012

20120255698

Method and Composition for Improved Temporary Wet Strength - A new process to make high solids polymer backbone with low molecular weight and narrow molecular weight distribution has been developed by a continuous polymerization processes under refluxing conditions. In this process, a mixture of acrylamide monomer, chain transfer agent and initiator is simultaneously and continuously added to the heel of aqueous solution under refluxing conditions.

10-11-2012

20130004617

COACERVATE COMPLEXES, METHODS AND FOOD PRODUCTS - Complex coacervates incorporating one or more hydrophobic substances are provided, that are stable in certain aqueous systems and food products. The coacervates may be used as an ingredient in food products, e.g., in beverages, dry foods, and semi-moist foods. Methods for producing the complex coacervates and food products are also disclosed herein.

01-03-2013

20130004640

COMPLEX COACERVATES, METHODS AND FOOD PRODUCTS - Complex coacervates incorporating one or more hydrophobic substances are provided, that are stable in certain aqueous systems and food products. The coacervates may be used as an ingredient in food products, e.g., in beverages, dry foods, and semi-moist foods. Methods for producing the complex coacervates and food products are also disclosed herein.

01-03-2013

20130056551

RELEASABLY ENCAPSULATED AROMA - Gelatin capsules encapsulating an aroma material including at least one aroma compound may be applied to product packaging, such as food packaging etc., with a secondary protective coating, e.g., at the interface of a container and its closure device. The gelatin capsules can be ruptured or broken when the container is opened, thereby releasing the aroma compound and causing a favorable aroma for the consumer. The secondary protective coating can reduce or prevent degradation of the gelatin capsules during product packaging, transport, and storage, thereby enhancing their performance.

03-07-2013

20130095210

Complex Coacervates and Aqueous Dispersions of Complex Coacervates and Methods of Making Same - Edible complex coacervates and aqueous dispersions of complex coacervates are disclosed, that may be utilized to protect a sensitive substance, e.g., fish oil or omega-3 fatty acids or other hydrophobic substances or sensitive hydrophilic substances. The complex coacervates and aqueous dispersions may be utilized in food products. Methods for producing the complex coacervates and aqueous dispersions are also disclosed.

04-18-2013

20130095211

Emulsions and Food Products Comprising Same and Methods for the Manufacture Thereof - Sensitive substance-in-wax solutions are disclosed that may be used to protect fish oil and other sensitive edible substances. Sensitive substance wax-in-water emulsions also are disclosed that are stable in food products, e.g., aqueous systems such as acidic beverages, and that may be used to protect sensitive edible substances. The Sensitive substance wax-in-water emulsions can be produced by combining the sensitive substance-in-wax solutions with anionic polymer. Food products comprising the sensitive substance-in-wax solutions and/or the sensitive substance wax-in-water emulsions and methods for producing the sensitive substance-in-wax solutions and the sensitive substance wax-in-water emulsions are also disclosed.

04-18-2013

20130251881

Method For Enhancing Rebaudioside D Solubility In Water - A clear Reb D solution is prepared by adding Reb D powder to water and heating to completely dissolve the Reb D powder, or by extracting Reb D from stevia plant using hot/boiling water or water/ethanol, wherein the temperature of the clear Reb D solution is above 70° C. Ideally, the clear Reb D solution is mixed with a solubilizing enhancer, wherein the temperature of the enhanced Reb D solution is maintained above 70° C., and wherein the solubilizing enhancer is a hydroxyl-containing sweetener. A stabilizer is then added to the Reb D solution to produce a stabilized Reb D solution; wherein the stabilizer comprises a thickener or anti-agglomeration agent. The stabilized Reb D solution is spray dried to form a powder. The solubility of Rebaudioside D is enhanced in water-based fluids, in particular in beverage concentrates and syrups

Stabilizing Sorbic Acid In Syrup And Finished Beverage - Sorbic acid or benzoic acid is stabilized in syrup and finished beverages by solubilizing potassium sorbate or sodium benzoate and then adding the solubilized potassium sorbate or sodium or potassium benzoate into a stabilizer solution at pH 2-4.

AUTOMATIC TUNING CONTROL SYSTEM FOR AIR POLLUTION CONTROL SYSTEMS - An automatic tuning control system and method for controlling air pollution control systems such as a dry flue gas desulfurization system is described. The automatic tuning control system includes one or more PID controls and one or more supervisory MPC controller layers. The supervisory MPC controller layers are operable for control of an air pollution control system and operable for automatic tuning of the air pollution control systems using particle swarm optimization through simulation using one or more dynamic models, and through control system tuning of each of the PID controls, MPC controller layers and an integrated MPC/PID control design.

Wei Zhang, South Windsor, CT US

Patent application number

Description

Published

20130180228

SUPERCRITICAL HEAT RECOVERY STEAM GENERATOR REHEATER AND SUPERCRITICAL EVAPORATOR ARRANGEMENT - A supercritical heat recovery steam generator includes a duct defining an interior area and having a gas inlet and a gas outlet. The duct is configured to convey gas from the gas inlet to the gas outlet. A portion of the duct between the gas inlet and the gas outlet defines an exhaust gas flow segment of the interior area. A supercritical evaporator is disposed in the interior area and a reheater is disposed in the interior area. The reheater and the supercritical evaporator are disposed in the exhaust gas flow segment, adjacent to each other with respect to the flow of the exhaust gas.

07-18-2013

20140374053

METHOD OF AIR PREHEATING FOR COMBUSTION POWER PLANT AND SYSTEMS COMPRISING THE SAME - Disclosed herein is a heat exchanger for transferring heat between a first gas flow and a second gas flow, the heat exchanger comprising at least two sectors; a first sector that is operative to receive a combustion air stream; and a second sector that is opposed to the first sector and that is operative to receive either a reducer gas stream or an oxidizer gas stream, and a pressurized layer disposed between the first sector and the second sector; where the pressurized layer is at a higher pressure than combustion air stream, the reducer gas stream and the oxidizer gas stream.

12-25-2014

Wei D. Zhang, South Windsor, CT US

Patent application number

Description

Published

20130180474

FLOW CONTROL DEVICES AND METHODS FOR A ONCE-THROUGH HORIZONTAL EVAPORATOR - Disclosed herein is a once-through evaporator comprising an inlet manifold; one or more inlet headers in fluid communication with the inlet manifold; one or more tube stacks, where each tube stack comprises one or more substantially horizontal evaporator tubes; the one or more tube stacks being in fluid communication with the one or more inlet headers; one or more outlet headers in fluid communication with one or more tube stacks; an outlet manifold in fluid communication with the one or more outlet headers; and a plurality of flow control devices to dynamically control the fluid flow to a respective inlet header.

07-18-2013

20130180696

A METHOD AND APPARATUS FOR CONNECTING SECTIONS OF A ONCE-THROUGH HORIZONTAL EVAPORATOR - Disclosed herein is a once-through evaporator comprising an inlet manifold; one or more inlet headers in fluid communication with the inlet manifold; one or more tube stacks, where each tube stack comprises one or more substantially horizontal evaporator tubes; the one or more tube stacks being in fluid communication with the one or more inlet headers; one or more outlet headers in fluid communication with one or more tube stacks; and an outlet manifold in fluid communication with the one or more outlet headers.

Chemical Synthesis of Hybrid Inorganic-Organic Nanostructured Corrosion Inhibitive Pigments and Methods - A method for preparing a hybrid inorganic-organic nanostructured inhibitive pigment, includes premixing a first stock solution containing one or more cations and a second stock solution containing one or more oxoanions to form a premixture under pH control in the presence of polymers as surface modifiers. The premixture is then reacted to form a slurry. The slurry is then quenched to separate nanoparticles from the slurry, followed by surface functionalization in organic inhibitors.

01-07-2016

20160002808

SOLUTION COMPOSITION AND METHOD FOR SINGLE-BATH POST TREATMENT OF SUBSTRATE - Disclosed is a solution composition which may be used for a single-bath electrochemical passivation and a method using the same. The solution composition includes a metal cation, a metal-oxide anion; and an organic ligand, and optionally includes a non-metallic oxide anion or a polymer. The solution composition may prevent undesired precipitation of metal oxides before performing passivation. In addition, the method of passivation using the solution composition in a single-bath use is also provided.

01-07-2016

Patent applications by Weilong Zhang, Glastonbury, CT US

Wenhua Zhang, Farmington, CT US

Patent application number

Description

Published

20160068720

HIGH TEMPERATURE DEBONDABLE ADHESIVE - A debondable adhesive composition comprises (A) the hydrosilation reaction product of the reaction between the vinyl groups on 1,3,5,7-tetravinyl-1,3,5,7-tetramethylcyclotetra-siloxane and the terminal Si—H hydrogens on a silane or siloxane having terminal Si—H hydrogens, (B) a cross-linker for the hydrosilation reaction product, and (C) a metal catalyst and/or a radical initiator. In further embodiments, this invention is an assembly of a substrate and a carrier for the substrate in which the debondable adhesive composition is disposed between the substrates, and a method for fabricating that assembly. The debondable adhesive composition maintains its adhesion at temperatures of 300° C. or greater, and is mechanically debondable at room temperature at a force less than 5N/25 mm.

03-10-2016

Xianman Zhang, Cheshire, CT US

Patent application number

Description

Published

20160002510

DIENE/DIENOPHILE COUPLES AND THERMOSETTING RESIN COMPOSITIONS HAVING REWORKABILITY - Thermosetting resin compositions are provided that are useful for mounting onto a circuit board semiconductor devices, such as chip size or chip scale packages (“CSPs”), ball grid arrays (“BGAs”), land grid arrays (“LGAs”) and the like (collectively, “subcomponents”), or semiconductor chips. Reaction products of the compositions are controllably reworkable when subjected to appropriate conditions.

Xuchen Zhang, Orange, CT US

Patent application number

Description

Published

20080318895

INTRANASAL DELIVERY OF NUCLEIC ACID MOLECULES - Aerosol delivery of nucleic acids to the lungs using viral vectors, polymers, surfactants, or excipients has been described. Compositions for intranasal administration are described that contain nucleic acids without viral or plasmid vectors and with little to no polymers, surfactants, or excipients. In one embodiment, the composition for intranasal delivery consists essentially of at least one nucleic acid and an aqueous solution. Suitable nucleic acids for intranasal delivery include, but are not limited to, dsDNA, dsRNA, ssDNA, ssRNA, short interfering RNA, micro-RNA, and antisense RNA Methods for treatment, diagnosis, or prevention of at least one symptom or manifestation of a lung disease are also described consisting of administration by intranasal delivery an effective amount of a composition containing a nucleic acid. The composition may be formulated as a liquid or aerosol or other acceptable formulation for intranasal administration.

12-25-2008

20100086546

Toll-LIke Receptor 4 Deficiency and Downstream Effectors Cause Pulmonary Emphysema - The present invention provides compositions and methods for the detection, treatment, and prevention of emphysema/COPD. Compositions of the present invention comprise TLR4 activators, Nox3 inhibitors, and Cathepsin E inhibitors useful in the treatment or prevention of emphysema/COPD. Cathepsin E is a downstream effector of TLR4, wherein when cathepsin E is overexpressed in lung of an individual, the individual is at higher risk of developing emphysema/COPD. Cathepsin E is further identified as a biomarker useful in the identification of an individual with, or at-risk of developing emphysema/COPD.

Xuehui Zhang, Storrs, CT US

Patent application number

Description

Published

20130019324

Embedded Ring Oscillator Network for Integrated Circuit Security and Threat Detection - Aspects of the disclosure relate to combining on-chip structure with external current measurements for threat detection in an integrated circuit. This method considers Trojans' impact on neighboring cells and on the entire IC's power consumption, and effectively localizes the measurement of dynamic power. An on-chip structure can permit threat detections. In one aspect, the on-chip structure can comprise a plurality of sensors distributed across the entirety of the IC, with each sensor of the plurality of sensors being placed in different rows of a standard-cell design. In another aspect, data analysis can permit separating effect of process variations on transient power usage of the IC from effects of a hardware threat such power usage. The on-chip structure also can be employed for implementation of a PE-PUF.

01-17-2013

20140103344

DETECTION OF RECOVERED INTEGRATED CIRCUITS - An apparatus for detection of integrated circuit recovery is disclosed. An example apparatus can comprise a first sensor embedded in an integrated circuit. The example apparatus can comprise a second sensor embedded in the integrated circuit. The example apparatus can comprise a selector unit configured to select one of the first sensor or the second sensor. The example apparatus can also comprise a monitor unit configured to receive output signal from the first sensor and the second sensor and to supply the output signal to an analysis unit.

04-17-2014

Yan Zhang, Coventry, CT US

Patent application number

Description

Published

20150316723

Fiber Optic Coupler Array - An assembly includes optical fibers each having a waveguide core, a photonic integrated circuit (IC) that includes in-plane waveguides corresponding to the optical fibers, and a substrate bonded to the photonic IC with grooves that support the optical fibers. The substrate and photonic IC can have metal bumps that cooperate to provide mechanical bonding and electrical connections between the substrate and photonic IC. Portions of the optical fibers supported by the substrate grooves can define flat surfaces spaced from the optical fiber cores. The photonic IC can include passive waveguide structures with a first coupling section that interfaces to the flat surface of a corresponding optical fiber (for evanescent coupling of optical signals) and a second coupling section that interfaces to a corresponding in-plane waveguide (for adiabatic spot-size conversion of optical signals).

Yongda Zhang, Sandy Hook, CT US

Patent application number

Description

Published

20140094609

PROCESS FOR THE PREPARATION OF AN HIV INTEGRASE INHIBITOR - The present invention is directed to an improved process for the preparation of Compounds of Formula (I), which are useful in the treatment of HIV infection. In particular, the present invention is directed to an improved process for the preparation of (2S)-2-tert-butoxy-2-(4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl)acetic acid, which is useful in the treatment of HIV infection.

04-03-2014

20140094610

PROCESS FOR THE PREPARATION OF AN HIV INTEGRASE INHIBITOR - The present invention is directed to an improved process for the preparation of Compounds of Formula (I) or salts thereof which are useful in the treatment of HIV infection. In particular, the present invention is directed to an improved process for the preparation of (2S)-2-tert-butoxy-2-(4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl)acetic acid or salt thereof which is useful in the treatment of HIV infection.

Yonghui Zhang, Old Saybrook, CT US

Patent application number

Description

Published

20090209703

Methods for Modulated Degenerative Transfer Living Polymerization and Isotactic-Atactic Stereoblock and Stereogradient Poly(Olefins) Thereby - Methods for modulated degenerative transfer living polymerization and isotactic-atactic stereoblock and stereogradient poly(olefins) thereby Abstract A method of producing a multiblock, stereoblock polyolefin having substantially uniform microstructure is disclosed. The method includes contacting a Ziegler-Natta pre-catalyst with a co-catalyst and an olefin to polymerize the olefin and form a first stereoblock, adding a methyl donator that changes the stereoregularity of the polymerization, and polymerizing the olefin to form a second stereoblock. The methods of the present invention allow for the production of poly(olefin)s having predictable degrees of incorporation of stereoerrors of a known type. The methods allows for the production of a variety of poly(olefin) microstructures, ranging from stereoblock to stereogradient poly(olefin)s and poly(olefin)s having fully isotactic to fully atactic microstructures.

08-20-2009

20090220786

Methods for Modulated Degenerative Transfer Living Polymerization and Isotactic-Atactic Stereoblock and Stereogradient Poly(Olefins) Thereby - Methods for modulated degenerative transfer living polymerization and isotactic-atactic stereoblock and stereogradient poly(olefins) thereby Abstract A method of producing a multiblock, stereoblock polyolefin having substantially uniform microstructure is disclosed. The method includes contacting a Ziegler-Natta pre-catalyst with a co-catalyst and an olefin to polymerize the olefin and form a first stereoblock, adding a methyl donator that changes the stereoregularity of the polymerization, and polymerizing the olefin to form a second stereoblock. The methods of the present invention allow for the production of poly(olefin)s having predictable degrees of incorporation of stereoerrors of a known type. The methods allows for the production of a variety of poly(olefin) microstructures, ranging from stereoblock to stereogradient poly(olefin)s and poly(olefin)s having fully isotactic to fully atactic microstructures.

Yu Chu Zhang, Norwalk, CT US

Patent application number

Description

Published

20110027436

USE OF THIOESTER FLAVORS TO IMPROVE THE FLAVOR QUALITY OF READY-TO-DRINK COFFEE UPON RETORTING AND STORAGE - The invention relates to a thermally processed ready to drink liquid coffee product having an improved flavor quality after thermal processing and storage due to the incorporation of a thioester flavor precursor at a concentration of 0.005 to 7 mg/kg. Preferably, the flavor precursor is furfurylthioacetate, methylthioacetate or prenylthioacetate or combinations thereof and not limited to the above. The invention also relates to a process for preparing the improved flavor quality of a thermally processed coffee product.

Yunchi Zhang, Wallingford, CT US

Patent application number

Description

Published

20120249263

SAME-BAND COMBINER USING DUAL-BANDPASS CHANNEL FILTERS - Various embodiments relate to an apparatus and related method for transmission and reception of a plurality of a carrier signals comprising one or more dual-band channels through a same-band combiner. A device such as a base station may include a same-band combiner that comprises a plurality of dual-bandpass filters and a combining element to transmit and receive the carrier signal. Each of the dual-bandpass filters may transmit and receive a channel, with each dual-bandpass filter including separate reception and transmission passbands for the separate frequencies in the dual-band channel. The combining element may separate and combine the one or more dual-band channels, with each of the dual-bandpass filters connected in parallel processing separate dual-band channels.

10-04-2012

20120249267

RADIO FREQUENCY FILTER STABILIZATION - An assembly and method relates to stabilizing a radio frequency (RF) filter with respect to a housing. The assembly can include a filter component; a housing having a groove to receive the filter component; a cover mounted to the housing to cover the groove; and an elastomeric element disposed between the cover and the filter. The elastomeric element may be one or more tubular pieces.

10-04-2012

20120264486

DC PASS FILTER USING FLAT INDUCTOR IN CAVITY - Various embodiments relate to a base station element and related method of suppressing an alternating-current (AC) portion of a signal. A base station element includes a filter capable of lightning suppression through the use of an LC filter that suppresses an AC portion of a received signal while passing a DC portion of the signal. The LC filter includes a flat inductor disposed in a cavity of the base station. The flat inductor may be connected to other electrical components disposed in the cavity of the base station to complete the electrical circuit. In some embodiments, the flat inductor may be produced from one material through photo-etching and may also include snap in or snap on connectors on one or both ends to enable galvanic contact with other components like a tap pin or a printed circuit board (PCB) without requiring attachment through soldering.

10-18-2012

20120313733

PLANAR FILTER ASSEMBLY - Various exemplary embodiments relate to a support assembly for a planar filter. The assembly includes a u-shaped housing with angled surfaces at the inner corners of the u-shape, a first dielectric plate having a first angled surface in contact with one of the angled surfaces of the housing, a second dielectric plate having a second angled surface in contact with the other angled surface of the housing, at least one compressible ring, and a cover. The planar filter is supported between the first dielectric plate and the second dielectric plate. The cover compresses the compressible ring to apply downward force on the first and second dielectric plates. The downward force is translated to an inward force by the angled surfaces of the housing. The angled surfaces of the housing apply an inward force on the first dielectric plate and the second dielectric plate.

12-13-2012

20140240197

Methods And Devices For Protecting Antenna Components From Contaminants - Sealing portions of an orthomode transducer or another antenna component is accomplished by forming first and second receptacles or channels in one half or portion of the transducer and inserting first and second type of compressible sealing components into the receptacles. Upon attaching additional portions of the transducer the compressible sealing components may be compressed, but the compression is limited to an amount within a compression range to maintain a seal.

08-28-2014

20140333394

Methods And Devices For Providing A Compact Resonator - A compact resonator is provided which includes a coupling that is connected to the resonator in between a resonator body and pedestal. The coupling may be keyed or otherwise fixed to prevent it from moving. Both deep drawn and solid resonator designs are provided.

11-13-2014

20140354375

Orthomode Transducers And Methods Of Fabricating Orthomode Transducers - Orthomode transducers (OMTs) and methods of fabricating OMTs are disclosed. According to disclosed embodiments, an OMT includes a housing defining an internal waveguide. The housing may be composed of a first cast housing member attached to a second cast housing member. The first housing member may include a first side of the waveguide that is cast into the first housing member. The second housing member may include a second side of the waveguide that is cast into the second housing member. A method of fabricating an OMT may include arranging at least one casting insert in at least one mold, casting the housing in the mold and casting a waveguide in the housing using the at least one casting insert. The disclosed devices and methods provide cost effective solutions for fabricating OMTs of various operating frequencies that share a substantially similar outer housing shape and size.

12-04-2014

20150207194

Methods And Devices For Grounding Deep Drawn Resonators - Difficulties in grounding a non-integral, deep drawn resonator (DDR) to the filter body of a cavity may be substantially eliminated by preventing the movement of the DDR away from a grounding contact area on the filter body. The addition of a compression plate and stop limiter in the connection of the non-integral DR to the filter body helps insure that any such movement is eliminated or substantially reduced.

Yunchi Zhang, Meriden, CT US

Patent application number

Description

Published

20100188174

COMPACT TUNABLE DUAL BAND STOP FILTER - Various exemplary embodiments include a technique for tuning a filter to have two stop bands. This technique may involve combination of signals from a plurality of high-band notch resonators and low-band notch resonators. Loop wires may couple both high-band and low-band notch resonators to a central conductor, thereby enabling the central conductor to transmit a signal having dual stop bands.

Yunlong Zhang, Danbury, CT US

Zhai Zhang, West Haven, CT US

Patent application number

Description

Published

20160033495

Detection of Non-Nucleic Acid Analytes Using Strand Displacement Exchange Reactions - The present invention relates to an analyte detection system for detecting analytes different from DNA and RNA. The system comprises a set of oligonucleotides which may hybridize to each other in specific ways and is able to generate a signal based on the specific hybridization events. The system relies on changes in the hybridization equilibrium between the oligonucleotides in the presence of an analyte or analytes, which results in a change in signal.

02-04-2016

Zhao Zhang, West Haven, CT US

Patent application number

Description

Published

20160033495

Detection of Non-Nucleic Acid Analytes Using Strand Displacement Exchange Reactions - The present invention relates to an analyte detection system for detecting analytes different from DNA and RNA. The system comprises a set of oligonucleotides which may hybridize to each other in specific ways and is able to generate a signal based on the specific hybridization events. The system relies on changes in the hybridization equilibrium between the oligonucleotides in the presence of an analyte or analytes, which results in a change in signal.

Zhonghua Zhang, Willimantic, CT US

Patent application number

Description

Published

20140256534

METAL OXIDE NANOROD ARRAYS ON MONOLITHIC SUBSTRATES - A metal oxide nanorod array structure according to embodiments disclosed herein includes a monolithic substrate having a surface and multiple channels, an interface layer bonded to the surface of the substrate, and a metal oxide nanorod array coupled to the substrate surface via the interface layer. The metal oxide can include ceria, zinc oxide, tin oxide, alumina, zirconia, cobalt oxide, and gallium oxide. The substrate can include a glass substrate, a plastic substrate, a silicon substrate, a ceramic monolith, and a stainless steel monolith. The ceramic can include cordierite, alumina, tin oxide, and titania. The nanorod array structure can include a perovskite shell, such as a lanthanum-based transition metal oxide, or a metal oxide shell, such as ceria, zinc oxide, tin oxide, alumina, zirconia, cobalt oxide, and gallium oxide, or a coating of metal particles, such as platinum, gold, palladium, rhodium, and ruthenium, over each metal oxide nanorod. Structures can be bonded to the surface of a substrate and resist erosion if exposed to high velocity flow rates.

09-11-2014

20150258531

Method of Making a Nanotube Array Structure - A method of making a nanotube array structure includes forming a nanorod array template on a substrate, coating a nanotube material over the nanorod array template, forming a coated template, annealing the coated template, and drying the coated template. The method then includes heating the coated template to an elevated temperature, relative to ambient temperature, at a heating rate while flowing a gas mixture including a reducing gas over the substrate at a flow rate, the reducing gas reacting with the nanorod array template and forming a gaseous byproduct and the nanotube array structure in which nanotubes may be substantially aligned with adjacent nanotubes. The nanotube array structure can be used, for example, in sensor, catalyst, transistor, or solar cell applications.

Indole acetic acid derivatives and their use as pharmaceutical agents - This invention is directed to indole acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation of indole acetic derivatives and to methods of preparation.