※ Computational resources of MHC binding epitopes :

Last updated: November 26th, 2011

Introduction :

Major histocompatibility complex (MHC) molecules play an important role in the immune system through capturing peptide antigens for display on cell surfaces, while different types of MHC molecules bind distinct peptides. These peptide-MHC complexes are recognized by T cells via their T-cell receptors, which resulted in that T-cell recognition is thus restricted to those peptides that the MHC molecules can present. Therefore, prediction of peptides which could bind to MHC molecules is important for identification of peptides capable of eliciting a T-cell response.

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