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Doctor insights on:
Stage 3 Colon Cancer Adjuvant Therapy

1

Advanced:
Breast cancer survival is correlated with it's stage, which is predominantly based on the cancer size, it's growth, and lymph node involvement. Stage 3 means that the cancer has grown into the chest wall or skin and/or multiple lymph nodes (including areas outside the armpit) are involved. These are all signs that chemotherapy is needed for potential cure.
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Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing repair of DNA damage.
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2

Excellent:
According to adjuvant online (www.Adjuvantonline.Com), you have about an 82% 10 yr survival rate based on your specific information provided. This is only an estimate since there are details I do not have such as type of chemotherapy being used. For triple negative breast cancer, these survival rates are quite excellent.
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5

Better now:
Exact prognosis is not possible, but your oncologist should discuss your prognosis with based on population statistics, such as Adjuvant! Online, or better still, your Oncotype Dx score based on the gene profile of your cancer.
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7

Monoclonals:
You are probably referring to monoclonal antibodies. These are complex molecules that have been engineered to interact with a specific phase in the cancer cell's biologic pathway. In other words, cancer cells frequently have mutations that are not present in normal cells. If we can block that pathway, then the cancer cell stops growing and dies. Expensive but fewer side effects.
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8

It depends:
Prognosis for Pancreatic Cancer is typically quite poor. But in some patients(5-10%) the tumor can be completely controlled but 90+ percent do tend to get into trouble in one to two years after Surgery.
Are you currently free of any visible Cancer in your abdomen? Tell us the details of your recent test results...do they show any tumors or have these been completely controlled???
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9

Depends:
What do you mean, "effective" ? In terms of survival, stage IV (metastatic) gastric cancer has a 5 year survival rate of only about 5%. Xeloda (capecitabine) is unlikely to significantly change this but ease of administration is a significant benefit. Overall, it is a promising agent although metastatic gastric cancer is a serious disease with high mortality rates.
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10

Very!:
Both stage i and ii mean that the cancer has not spread to the lymph nodes and as such, they are much more easily treated with very high survival rates. Surgery alone is generally adequate unless someone with stage ii has high risks.
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12

Yes, major differenc:
Stage 2 ovarian cancer(spread limited to pelvic area only has a much better cure rate(>50%) than with stage-3 Ovarian cancer which means it has spread into the belly). Stage 3 is the most common stage of presentation; this means high mortality rate, yet 25% to 30% of such women can expect to be cured with the proper use of modern chemotherapy combined with debulking surgery.
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13

Early detection!:
The best thing that improves the chances of curing colon cancer is early detection. So preventive health care and screening are key. All adults should have a colonoscopy at age 50 to look for cancers or early cancers, usually as polyps. If you have a strong family history or certain conditions it is recommended you get earlier screening.Once detected, colon ca usually is cured by surgery, or drugs.
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14

Yes but:
It could possibly spread to local lymph node but the chances are very low. The lymph nodes that are in thoracic cavity are even less likely to contain metastatic tumor from a stage 1a endometrial cancer, especially if it's a garden variety low grade lesion. In fact, long term survival is very good, like 95%. The other 5% may represent very high grade tumors.
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15

Yes:
Untreated bladder cancer can metastasize to other organs and structures when left untreated. The more aggressive the bladder cancer, the higher the likelihood of metastasis. It is not unusual for bladder cancer to metastasize.
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16

Depends on type:
Survival can range from 60% to as high as 90+%. Survival is individual and depends on cancer type, treatment, and general health at time of diagnosis. Best outcomes are achieved with a multi-discipline thoracic oncology approach. These links may assist you with some general background information: http://goo.Gl/uwomy and http://goo.Gl/mo7uz and http://goo.Gl/ul4di.
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17

Depends:
Radiation is one method of treating lung cancer, and is effective if the lesion is small, and peripherally located. Once the lesion is treated, a scar will remain. This needs to be followed, since complete clearance can only be determined by surgical resection.
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18

Stage IIB LngCa:
Iib is a 5-7 cm tumor and n1 node positive, or >7 cm , or invasion into a resectable structure, or collapse of an entire lobe with no nodes positive. This is quite rare. If resected and proven to be just the features above, many would add chemotherapy or radiotherapy. Regardless, the survival is between 30 and 50% at 5 yrs, meaning 50 -70% die before then.
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20

Herceptin (trastuzumab):
Herceptin (trastuzumab) is approved for the treatment of early-stage breast cancer that is human epidermal growth factor receptor 2-positive (her2+) and has spread into the lymph nodes, or is her2+ and has not spread into the lymph nodes. If it has not spread into the lymph nodes, the cancer needs to be estrogen receptor/progesterone receptor (er/pr)-negative or have one high risk feature.
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The colon is another term for the large intestine. This is the final portion of the digestive system, responsible for absorbing water and storing stool before evacuation. It is divided into sections described as cecum; ascending, transverse, descending and sigmoid colons; and rectum.
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