Effect of oral contraceptives and DMPA on tenofovir PK, PD, and safety by comparing the following endpoints before initiation of contraceptive method and 10 weeks after initiation of contraceptive method

Effect of the menstrual cycle of the tenofovir PK, PD, and safety by comparing the following endpoints 3 and 1 hours after insertion of 2 doses of study gel, in the follicular and luteal phases before initiating contraception

To assess the effect of oral contraceptives and DMPA on markers of mucosal immunity by comparing the following endpoints (in the absence of tenofovir) before initiation of contraceptive method and 10 weeks after initiation of contraceptive method

72

Female

18 Years to 50 Years (Adult)

NCT01421368

A10-114

March 2012

March 2014

March 2014

August 22, 2011

April 10, 2015

University of Pittsburgh School of Medicine, Center for Family Planning ResearchPittsburgh, Pennsylvania, United States