Useful in the assessment of deficiency or overload. Copper, Serum Free (Direct) (0020596) may be a more specific indicator of copper overload. For the complete assessment of copper overload, Wilson Disease Screening Panel, Serum (0020598) is preferred.

Separator tubes and specimens that are not separated from the red cells or clot within 6 hours.

Remarks

Stability

If the specimen is drawn and stored in the appropriate container, the trace element values do not change with time.

Reference Interval

Effective November 14, 2011

Age

Male

Female

0-10 years

75-153 µg/dL

75-153 µg/dL

11 years-12 years

64-132 µg/dL

64-132 µg/dL

13 years-18 years

57-129 µg/dL

57-129 µg/dL

19 years and older

70-140 µg/dL

80-155 µg/dL

Interpretive Data

Serum copper may be elevated with infection, inflammation, stress, and copper supplementation. In females, elevated copper may also be caused by oral contraceptives and pregnancy (concentrations may be elevated up to 3 times normal during the third trimester).

Serum copper may be reduced by use of corticosteroids and zinc and by malnutrition or malabsorption.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note

Elevated results from noncertified trace element-free tubes may be due to contamination. Elevated concentrations of trace elements in serum should be confirmed with a second specimen collected in a trace element-free tube, such as royal blue sterile tube (no additive).

* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Provide Feedback on ARUP Lab Test Directory

*I want to provide feedback regarding:Please select a feedback type

*Test Number:Please enter a test name or number

Please type your message. If you are reporting a problem, please indicate what you
were trying to do when the problem occurred, what you expected to happen, and what actually happened:*CommentPlease enter a comment