Macrophage activation syndrome (MAS) is a potentially fatal complication caused by excessive activation and expansion of macrophages and T lymphocytes. It can be triggered by various infections and is characterized by the development of cytopenias, hyperferritinemia, liver dysfunction, and coagulopathy. We report a 10-month-old female infant with fever, convulsions, and hepatosplenomegaly. Laboratory data of bicytopenia, low erythrocyte sedimentation rate, and elevated liver enzymes suggested MAS. This was supported by the presence of hyperferritinemia with hypertriglyceridemia. MAS was triggered by influenza B virus. She responded to treatment with immunoglobulin and steroid.

A letter to the editor is presented which discusses a case study of a 19 year old man related to the treatment of Subcutaneous panniculitis-like T cell lymphoma (SPTCL) with haemophagocytic syndrome (HPS) and diagnosis of macrophage activation syndrome.

Macrophage activation syndrome (MAS) is a potentially fatal condition. It belongs to the hemophagocytic lymphohistiocytosis group of diseases. In adults, MAS is rarely associated with systemic lupus erythematosus, but it also arises as complication of several systemic autoimmune disorders, like...

Systemic clinical presentations of infection caused by Bartonella henselae are rare in immunocompetent adults. We report four cases with hepatic and/or splenic involvement, presenting as fever of unknown origin. We discuss diagnosis and treatment of this infection. Bartonella henselae serology...

Hypertriglyceridemia (HTG) is commonly encountered in lipid and cardiology clinics. Severe HTG warrants treatment because of the associated increased risk of acute pancreatitis. However, the need to treat, and the correct treatment approach for patients with mild to moderate HTG are issues for...

The article presents a case study of a 46-year-old woman who was hospitalized due to prolonged high-grade fever, night sweats and weight loss. Her diagnostic findings include enlarged liver and spleen, edema, pancytopenia and hemophagocytosis, and she was diagnosed with hemophagocytic syndrome....

Objective: To describe an uncommon case of acute necrotizing encephalopathy of childhood Case report: Acute necrotizing encephalopathy of childhood (ANEC) is a clinical neurological entity that predominantly affects young children in Far Eastern countries. It presents with rapid onset...

The article discusses the clinical subtypes of juvenile idiopathic arthritis (JIA), with reference to prognosis in adolescence and adulthood. It discusses advancements in medical treatment, and potential complications and emergencies relevant to hospital medicine. It presents tables...