Figure 7.

Effect of muraglitazar on carrageenan-induced paw oedema in the mouse. Muraglitazar, inducible nitric oxide synthase (iNOS) inhibitor L-NIL, dexamethasone
or vehicle (2.0% CMC) were given to animals per os 1 hour prior to carrageenan injection
(1%). Paw oedema was measured before and one, four and six hours after carrageenan
injection by micrometer. Oedema is expressed as increase in paw thickness at indicated
time points compared to thickness before carrageenan. Values are mean + SEM (n = 6). *P <0.05 and **P <0.01 as compared to mice treated with carrageenan alone.