Adzenys ER is a once-daily extended-release liquid that does not need to be reconstituted or refrigerated. Other ADHD extended-release medications from Neos include Adzenys XR-ODT (amphetamine) extended-release orally-disintegrating tablets and Cotempla XR-ODT (methylphenidate) extended-release orally-disintegrating tablets.

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Adzenys ER and Adzenys XR-ODT are considered bioequivalent to Adderall XR. Amphetamines are non-catecholamine sympathomimetic amines with central nervous system (CNS) stimulant activity; the exact mechanism of action is unknown.

Adzenys ER, a CII controlled substance, will be available as a 1.25mg/mL strength orange-flavored suspension in 450mL bottles. It is expected to launch early next year.