PHYSICAL METHODS IN ORGANIC CHEMISTRY AND LABORATORY

LEARNING OUTCOMES OF THE COURSE UNIT

Knowledge and understanding
The aim of the course is to provide students with a thorough knowledge of the most common advanced 1D and 2D NMR techniques for the structural analysis or organic compounds.

Applying knowledge and understanding
The student will be able to identify autonomously the structure of an organic compound through the interpretation of several 1D and 2D NMR spectra.

PREREQUISITES

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COURSE CONTENTS SUMMARY

Magnetic properties of nuclei: angular momentum and spin angular momentum. The Vector model. Fundamental concepts of 2D NMR spectroscopy. Relaxation processes. The Chemical exchange. The modern NMR spectrometer. Interpretation of 1D e 2D NMR spectra and determination of the structure of an organic compound.
Laboratory: Synthesis of an organic compound and its structural characterization through advanced NMR techniques.

ASSESSMENT METHODS AND CRITERIA

The final examination will include a written part in which the candidates have to assign the structure of a known organic compounds to the resonances of several 1D and 2D NMR spectra. In the following oral part, the candidates will be enquired on the theoretical topics discussed during the first part of the course.

TEACHING METHODS

The format of the class will be lectures of one or two hours each spread over three mornings per week. A regular class meetings will be composed of lecture and class exercises.
The lab training will be articulated in four turns of four hours each.

FURTHER INFORMATIONS

This course offers the “Book exam” option. The lectures are held in Italian, but Erasmus/foreign students can complete the course by choosing the “book exam” option: this means that you read and study the literature specifically agreed on with the lecturer/professor and then take a written examination in English.