Scott Karl won 54 games in the majors and another 38 in the minors. His minor league ERA was under 3.00.

In his final start of 1995, pitching for the Milwaukee Brewers, Karl threw his first complete game, doing so with only 97 pitches while pounding the strike zone to the tune of over 70% strikes. Karl went 13-9 with the Brewers in 1996, a sub-.500 team.

Through 2008, he and Andy Karl are the only two major leaguers with the last name "Karl".