IACC Autism Spectrum Disorder Research Portfolio Analysis: Project Listing
Project Id Project Number Sub Project Number Funder Principal Investigator Project Title Project Description Fiscal Year Funding Category Subcategory Strategic Plan Objective Objective Status Code Arra Funded? Federal/Private Institution State/Country Project Status Web Link 1 Web Link 2 Web Link 3 Active Current Award Period
Project Id: 2286 Project number unavailable None Autism Speaks Law, Paul Interactive Autism Network (IAN) Interactive Autism Network (IAN) Research is a scientific study where individuals with autism spectrum disorder (ASD), their families, and qualified researchers throughout the United States work together to understand ASD. IAN Research connects researchers to individuals with ASD and their families to uncover the secrets of this complex disorder. Participants provide information in a secure online setting about diagnosis, behavior, family, environment, and services received. Participating parents report on their child's progress over time. Adults with ASD share information about their experiences and needs. Researchers from different institutions throughout the country will work with this information to learn about the effect and interaction of factors such as genetics, environment, and treatment, as well as the current situation and needs of those affected by ASD. IAN Research will match willing individuals and families with appropriate local and national research projects. $1,320,000.00 Infrastructure N/A Question 7: Objective C Green dot: Objective has greater than or equal to the recommended funding. No Private Kennedy Krieger Institute Maryland Ongoing http://www.iancommunity.org/ No URL available. No URL available. active na
Project Id: 2188 1R01MH087756-01 None National Institutes of Health Das, Amarendra CRCNS: Ontology-based multi-scale integration of the autism phenome Finding genetic variants that predispose and regulate brain-related disorders has become a significant area of neuroscience research. However, limited success has been achieved with mental disorders such as autism, partly due to the difficulty in identifying endophenotypes, or intermediate phenotypes, of the disorder. Phenomics - the systematic cataloging of phenotypes on a genome-wide scale - has emerged as a scientific endeavor within psychiatric genetics to address this challenge. A limitation to the advancement of phenomics, however, is the lack of available methods and tools for modeling, managing, and reasoning about endophenotypes. This project will develop the Phenologue, a novel knowledge-based technology that can support collaborative efforts to acquire, manage, and reason about a disease phenome given experimental data and published findings. Among the project's research objectives are to develop an ontology of endophenotypes that maps brain connectivity, neural deficits, and genetic markers to develop logic-based methods to encode and classify endophenotypes, and to create tools to acquire new endophenotypes and annotate phenotype-genotype findings in online resources such as published literature. The research will help develop an autism ontology for the National Database for Autism Research (NDAR). $345,180.00 Infrastructure N/A Question 7: Objective C Green dot: Objective has greater than or equal to the recommended funding. No Federal Stanford University California New http://projectreporter.nih.gov/project_info_description.cfm?aid=7778021&icde=6636132 No URL available. No URL available. active na
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