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We report a patient who presented with unilateral periorbital edema after a short-term travel to an endemic area for Chagas disease and exposure to triatomine (reduviid) bugs. The diagnosis, however, was furuncular myiasis, not Chagas disease. This case emphasizes that there are multiple parasitic agents besides Trypanosoma cruzi that may be associated with clinical findings consistent with Romaña sign.

From the *Division of Infectious Diseases, Department of Medicine and †Department of Surgery, New York Medical College, Valhalla, NY; ‡Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA and §New York State Department of Health, Buffalo, NY.

The findings and conclusions in this article are those of the authors and do not necessarily represent the views of the Centers for Disease Control and Prevention or the New York State Department of Health.