Sir: Since 1979, there have been reports of extrapyramidal
effects, including dystonia, akathisia, and parkinsonism, associated
with the use of serotonin selective reuptake inhibitors
(SSRIs) in young, healthy patients. There are few reports of
SSRI-related extrapyramidal effects in the elderly or neurologically
impaired, although such individuals might be more
vulnerable. French physicians reported deterioration of parkinsonian
patients taking SSRIs.