Efforts to develop a hormonal contraceptive regimen for men have focused
on administration of testosterone (T), alone or together with other
agents. Previous regimens have successfully induced azoospermia in ...

GnRH antagonists have been developed in large part because of their
potential use as contraceptive agents, particularly in men. Specifically,
it was hoped that GnRH antagonists combined with testosterone (T) ...

OBJECTIVE: To test the hypothesis that over a 4-week treatment period,
Nal-Glu GnRH antagonist ([AcD2Nal1, D4ClPhe2, D3Pal3, Arg5, DGlu6 [AA],
DAla10] GnRH) at a dose of 200 micrograms/kg per day SC would ...

The importance of androgens in establishing and maintaining sexual
function in males of most species is well recognized. Estrogens also
stimulate male sexual function in some species. In men, most studies ...

GnRH analogs, both agonists and antagonists, have potential use in
androgen-dependent diseases of older men, such as prostatic cancer and
benign prostatic hyperplasia. Previous experience with agonists of ...

Women with luteal phase deficiency have been shown to have an increased
frequency of luteinizing hormone pulses in the early follicular phase of
the menstrual cycle. Because progesterone is known to modulate ...

In addition to their use as replacement therapy for hypogonadal males,
androgens, particularly testosterone (T), are being explored as potential
hormonal male contraceptive agents, alone or in combination ...

Premenopausal women have a lower risk of coronary artery disease than men
or postmenopausal women; estrogens are thought to contribute to this lower
risk. Administration of exogenous estrogen to post-menopausal ...