Acute NEPHRITIC syndrome 1-2 weeks after infection with Group A Beta-hemolytic Streptococci

A 10 year old girl presents to the clinic complaining of eye swelling. You remember this child from 3 weeks ago when she was seen for Pharyngitis. Upon taking a history and performing a physical, you find that the patient has pronounced periorbital edema, has been urinating very little despite adequate fluid intake, and has a blood pressure of 150/9. Lab findings include Azotemia, Hematuria, Red Cell Casts in the urine, and increased ASO Ab titer.

Acute Postinfectious Glomerulonephritis

**Immune-complex disease

What age group does Acute Postinfectious Glomerulonephritis usually occur in?

When azotemia becomes associated with a constellation of clinical signs and symptoms

Uremia

Prerenal azotemia is encountered when there is _______ that impairs renal function in the ABSENCE of parenchymal damage

Hypoperfusion

When is Postrenal Azotemia seen?

whenever flow is obstructed below the level of the kidney

X-linked dominant disease with a defect in the synthesis of the alpha5-subtype of collage type IV in the GBM

Alport's Syndrome

A patient presents with hereditary nephritis, sensorineural hearing loss, and ocular defects. What is the diagnosis?

Alport Syndrome

A 10-year-old boy presents to the clinic complaining of a red tinge to his urine. A more detailed history reveals that he was diagnosed with mild nerve deafness 2 years earlier and also developed cataracts 1 year ago. Lab studies confirm hematuria as well as the presence of RBC casts

Alport syndrome

Development abnormality that may be uni- or bilateral. Results from irregular differentiation and morphogenesis of the Metanephros. Parenchyma of these abnormal kidneys consists of immmature nephrons, often showing signs of Cystic dilation