Chloramphenicol (Chloromycetin)

Chloramphenicol is an antibiotic first derived from cultures of the soil bacterium Streptomyces venezuelae in the late 1940s. Although this drug was commonly used in the 1950s and 1960s, it is now reserved for microbial infections that are resistant to antibiotics that have fewer side effects. There are numerous adverse reactions to the drug including bone marrow depression, gastrointestinal reactions, neurotoxicity, and hypersensitivity.