Oooh, there's a few I really like for all three. I'll list some noteworthy ones with little mini-reviews!

GB/GBC:Game & Watch Gallery 1, 2, 3 are all really cool collections of Gunpei Yokoi's Game & Watch handheld games. There's modern versions of the games with Mario & friends and classic versions that faithfully emulate the original handhelds.

Legend of the River King is a fishing RPG with a calming atmosphere, well-done graphics and music, and heck, it's a rad fishing RPG! It's a nicely-done concept, I'd like to see more of it someday.

Mario Tennis is a tennis RPG about a boy who trains to become the bestest tennis player ever. Mario and friends aren't in the game until the postgame, actually! But I think everyone knows that by now. It's solid and you can upload your player character to Mario Tennis 64 if you wish!

GBA:

WarioWare Twisted is a bunch of gyroscope-controlled microgames that are frantic, funny, and REALLY well-done. I wonder why I can't think of a game that's used a gyroscope better even though gyroscopes are commonplace nowadays.

Advance Wars and Duel Strike are must-plays for anybody who has a GBA. It's a light-hearted Intelligent Systems strategy game with a huge variety of units. It's legendary for a reason.

Mario & Luigi Superstar Saga is probably one of the best RPGs ever made. Seriously. It's bursting with character and charm, the gameplay is unique and interesting, think Paper Mario with two playable characters that can perform a wide variety of combination attacks that require quick reflexes and good timing. There's a 3DS remake, but it's kinda meh. Play either one.

Some great suggestions here, but the lack of any mentions of Bionic Commando makes me a sad panda. Such a criminally over-looked and under-appreciated title... so sad... tears...

Great graphics (for a GB game), excellent soundtrack (even better than the NES counterpart, which set the bar high itself), excellent controls, great level design.. and you no longer have to exit completely out of a level to switch out your comm device if you selected the wrong one.

A lot of Gameboy games can feel like cheaper experiences compared to their NES counterparts, but Bionic Command on the B&W Gameboy I feel is the other way around. Other than lacking color, which doesn't bother me at all personally, this is far superior in every way to the NES Bionic Commando. That it's portable and on the go as well just makes it that much sweeter.

Another great title often over-looked is Ninja Gaiden Shadow. Although despite the name it isn't quite a Ninja Gaiden game, it appears to have been renamed that for the NTSC region from Shadow Warriors. But we're splitting hairs now, what matters is that just like the previously mentioned Bionic Commando, this game is the compete package: graphics, sound, gameplay, level design.. all top notch. Always an incredible achievement with the tight hardware restrictions of the Gameboy. The first level even boasts an impressive parallax background scrolling illusion.

And lastly, Rolan's Curse 2. The overworld theme alone is quite possibly the catchiest piece of chiptune to have ever graced my ears. You could tie me to a chair and force me to listen to it for days and I'd feel great. This game is a top-down RPG that even boasts a multi-player option. Haven't had a chance myself to ever try it though, so can't say much in regards to that, but even solo this is a great RPG that appears entirely forgotten.

Squeegor wrote:Another great title often over-looked is Ninja Gaiden Shadow. Although despite the name it isn't quite a Ninja Gaiden game, it appears to have been renamed that for the NTSC region from Shadow Warriors.

Actually Ninja Gaiden Shadow is the original (western) name and it was renamed Shadow Warriors for the European release. The NG arcade game, most of its ports and the NES title were also originally renamed Shadow Warriors.

You're correct to say it isn't quite a Ninja Gaiden game however, as it was originally going to be a Game Boy Shadow of the Ninja title. Play Shadow of the Ninja (NES, re-released in recent years on Wii/Wii U/3DS) and you'll notice the similarities.

Squeegor wrote:Another great title often over-looked is Ninja Gaiden Shadow. Although despite the name it isn't quite a Ninja Gaiden game, it appears to have been renamed that for the NTSC region from Shadow Warriors.

Actually Ninja Gaiden Shadow is the original (western) name and it was renamed Shadow Warriors for the European release. The NG arcade game, most of its ports and the NES title were also originally renamed Shadow Warriors.

You're correct to say it isn't quite a Ninja Gaiden game however, as it was originally going to be a Game Boy Shadow of the Ninja title. Play Shadow of the Ninja (NES, re-released in recent years on Wii/Wii U/3DS) and you'll notice the similarities.

Ah seems I got it the other way around, thank you for the clarification.

But yeah even from my very first play-through it just seemed a bit 'different' from the other Ninja Gaiden games. But still a fantastic game, especially in a portable format you can take on the go. And at least unlike the NES Ninja Gaiden games, the challenge level wasn't obscene.