"She can go f--k herself!" Brandi Glanville fired back tonight when ex-husband Eddie Cibrian's new wife, LeAnn Rimes, was brought up during a Q&A session during her book-signing for Drinking and Tweeting: And Other Brandi Blunders at Palihouse in West Hollywood hosted by Gilt City Los Angeles.

"Well, she has to, because who would want to?" the Real Housewives of Beverly Hills star added naughtily.

That obviously proved to be a rhetorical question, and Glanville did admit that, sometimes, she says things and "then I go home and think about them. I have a conscience. I definitely feel bad about certain things and when I'm wrong I say sorry."

But when someone goes after her (as seen on RHOBH), "I go 10 times harder," she said. "Especially when it comes to my family and my children—bitch, it's on!"

"Heartbreak is universal," she said, noting one of the revelations she had while writing Drinking and Tweeting. "I think for women to hear me complain about what happened to me, it makes them feel better about what they've gone through."

As for her marriage to Cibrian, which produced two sons before ending in the summer of 2009, Glanville maintains she tried her best to make it work.

"I did everything right," she recalled. "I loved so hard. I loved my children and my family was perfect. I did everything I could do for him and the boys and to make him not want to stray. So, when it happened, especially with someone as attractive as her..."

"When a man cheats on you its not about you," she concluded. "It's about notoriety. They want to be with you but they want their cake and eat it too."

But, she added, she hopes Cibrian and Rimes make it work—if only "because I don't want my kids to go through a divorce again."

As for the happy couple's reaction to her book? "I'm expecting a cease-and-desist," Glanville joked. But "after this happens, after the book is out," she added, "I promise I'm closing this chapter of my life."