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Director of rugby Todd Blackadder said: “Sam showed symptoms again, so that's not great We'll have to see how he goes this week."

Sam Underhill walks into Twickenham (Image: Dan Mullan/Getty Images)

Francois Louw is unlikely to play against the three-time European champions. He picked up a shoulder injury playing for South Africa against Italy and Blackadder is not sure when the back-row scavenger will be fit again.

"He's more than likely ruled out this week," the DoR said. "Hopefully Francois just needs a rest."