* smoke;
* drink alcohol;
* have an ulcer or bleeding in the stomach;
* have liver disease;
* have kidney disease;
* have asthma;
* have congestive heart failure;
* have fluid retention;
* have heart disease;
* have high blood pressure;
* have a coagulation (bleeding) disorder or are taking an anticoagulant
(blood thinner) such as warfarin or
are taking a steroid medicine such as prednisone , methylprednisolone,
prednisolone , and others.

You may not be able to take valdecoxib, or you may require a dosage
adjustment or special monitoring during treatment if you have any of the
conditions, or are taking any of the medicines, listed above.