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Novel computer model designed to understand cardiovascular diseasesResearchers have developed a novel three-dimensional, multiscale and multicomponent model of endothelial cells monolayer, the inner lining of artery, to identify the cellular mechanisms involved in cardiovascular diseases (CVD). New research based on the model is able to identify the main cellular pathways involved in the initiation and progression of the disease. http://medicalxpress.com/news/2015-02-cardiovascular-diseases.html
Medical researchWed, 25 Feb 2015 10:00:03 ESTnews344078623Blood test distinguishes premature births from 'false alarms'Women who give spontaneous preterm birth have specific genetic signatures which doctors can now detect with a simple blood test.http://medicalxpress.com/news/2014-06-blood-distinguishes-premature-births-false.html
Obstetrics & gynaecologyThu, 19 Jun 2014 09:50:01 ESTnews322387547Scientists use nature against nature to develop an antibiotic with reduced resistanceA new broad range antibiotic, developed jointly by scientists at The Rockefeller University and Astex Pharmaceuticals, has been found to kill a wide range of bacteria, including drug-resistant Staphylococcus (MRSA) bacteria that do not respond to traditional drugs, in mice. The antibiotic, Epimerox, targets weaknesses in bacteria that have long been exploited by viruses that attack them, known as phage, and has even been shown to protect animals from fatal infection by Bacillus anthracis, the bacteria that causes anthrax.http://medicalxpress.com/news/2013-04-scientists-nature-antibiotic-resistance.html
MedicationsWed, 10 Apr 2013 17:00:02 ESTnews284831058Study shines light on how stress circuits learnResearchers at the University of Calgary's Hotchkiss Brain Institute have discovered that stress circuits in the brain undergo profound learning early in life. Using a number of cutting edge approaches, including optogenetics, Jaideep Bains, PhD, and colleagues have shown stress circuits are capable of self-tuning following a single stress. These findings demonstrate that the brain uses stress experience during early life to prepare and optimize for subsequent challenges.http://medicalxpress.com/news/2013-04-stress-circuits.html
NeuroscienceSun, 07 Apr 2013 13:00:02 ESTnews284557977Sensory hair cells regenerated, hearing restored in mammal earHearing loss is a significant public health problem affecting close to 50 million people in the United States alone. Sensorineural hearing loss is the most common form and is caused by the loss of sensory hair cells in the cochlea. Hair cell loss results from a variety of factors including noise exposure, aging, toxins, infections, and certain antibiotics and anti-cancer drugs. Although hearing aids and cochlear implants can ameliorate the symptoms somewhat, there are no known treatments to restore hearing, because auditory hair cells in mammals, unlike those in birds or fish, do not regenerate once lost. Auditory hair cell replacement holds great promise as a treatment that could restore hearing after loss of hair cells.http://medicalxpress.com/news/2013-01-sensory-hair-cells-regenerated-mammal.html
NeuroscienceWed, 09 Jan 2013 12:00:07 ESTnews276953524Novel drug therapy targets aggressive form of non-Hodgkin's lymphomaDiffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin's lymphoma and the seventh most frequently diagnosed cancer. The most chemotherapy resistant form of DLBCL, called activated B-cell – DLBCL (ABC-DLBCL), remains a major therapeutic challenge. An international research team, led by two laboratories from Weill Cornell Medical College, has developed a new experimental drug therapy to target this aggressive form of lymphoma.http://medicalxpress.com/news/2012-12-drug-therapy-aggressive-non-hodgkin-lymphoma.html
CancerMon, 10 Dec 2012 15:46:52 ESTnews274376793Targeting downstream proteins in cancer-causing pathway shows promise in cell, animal modelThe cancer-causing form of the gene Myc alters the metabolism of mitochondria, the cell's powerhouse, making it dependent on the amino acid glutamine for survival. In fact, 40 percent of all "hard-to-treat" cancers have a mutation in the Myc gene.http://medicalxpress.com/news/2012-11-downstream-proteins-cancer-causing-pathway-cell.html
CancerTue, 13 Nov 2012 14:54:46 ESTnews272040879Discovery shows medications can treat inflammation without increasing risk for infectionIn a discovery that can fundamentally change how drugs for arthritis, and potentially many other diseases, are made, University of Utah medical researchers have identified a way to treat inflammation while potentially minimizing a serious side effect of current medications: the increased risk for infection.http://medicalxpress.com/news/2012-11-discovery-medications-inflammation-infection.html
Inflammatory disordersSun, 11 Nov 2012 13:00:44 ESTnews271860828Genetic test developed for those at-risk for Autism Spectrum Disorder: Accuracy to be studied(Medical Xpress)—A team of Australian researchers, led by University of Melbourne has developed a genetic test that is able to predict the risk of developing Autism Spectrum Disorder, ASD.http://medicalxpress.com/news/2012-09-genetic-at-risk-autism-spectrum-disorder.html
Autism spectrum disordersWed, 12 Sep 2012 08:26:30 ESTnews266655952New biomarker for common lung cancer predicts responses to chemotherapyPatients with the most common type of lung cancer are notoriously insensitive to chemotherapy drugs, including cisplatin. New findings related to the cellular pathways that regulate responses to cisplatin have now been published by Cell Press on July 26th in the journal Cell Reports. The findings reveal a potential biomarker that can be used to predict how these patients will respond to chemotherapy, as well as the patients' overall prognosis, paving the way for personalized treatment strategies.http://medicalxpress.com/news/2012-07-biomarker-common-lung-cancer-responses.html
CancerThu, 26 Jul 2012 12:20:09 ESTnews262519571Estrogen hormone reveals protective ability after traumatic brain injuryWith more than 1.7 million people sustaining a traumatic brain injury each year, the need to identify processes to limit inflammation and subsequent damage is critical. Approximately 275,000 people are hospitalized annually with traumatic brain injury, leaving 85,000 with long-term disabilities and taking the lives of more than 50,000. More than 5 million people live with disabilities caused by traumatic brain injuries, often the result of car accidents and falls. Direct and indirect costs exceed $75 billion.http://medicalxpress.com/news/2012-04-estrogen-hormone-reveals-ability-traumatic.html
Medical researchMon, 23 Apr 2012 04:03:52 ESTnews254372618Researchers examine role of inflammatory mechanisms in a healing heart(Medical Xpress) -- Virginia Commonwealth University researchers have found that an inflammatory mechanism known as inflammasome may lead to more damage in the heart following injury such as a heart attack, pointing researchers toward developing more targeted strategies to block the inflammatory mechanisms involved.http://medicalxpress.com/news/2011-11-role-inflammatory-mechanisms-heart.html
Inflammatory disordersWed, 30 Nov 2011 06:48:07 ESTnews241858027Growth hormone helps repair the zebrafish earLoud noise, especially repeated loud noise, is known to cause irreversible damage to the hair cells inside the cochlea and eventually lead to deafness. In mammals this is irreversible, however both birds and fish are able to re-grow the damaged hair cells and restore hearing. New research published in BioMed Central's open access journal BMC Neuroscience shows that growth hormone is involved in this regeneration in zebrafish.http://medicalxpress.com/news/2011-09-growth-hormone-zebrafish-ear.html
NeuroscienceFri, 02 Sep 2011 09:12:58 ESTnews234173568