I have had acne since I was 13 (now 42) and though I have had clear periods within this time frame (after Accutane) it always ended up creeping back. I am a master at covering a pimple but was SO tired of a new pimple on the horizon! The dermatologist said "Accutane would not be my choice for you" and prescribed 100 mgs of Spironolactone. I am in my 9th week of medicine and WOW what a difference. My skin is clear, feels smooth, pores have shrunk and no more grease! Well worth the patience. Wish I had been prescribed this years ago!