Gingerol

Gingerol ([6]-gingerol), a pungent vanilloid isolated from ginger rhizomes (Zingiber officinale), is a novel and selective activator of skeletal and cardiac SR Ca2+-ATPase (EC50=4µM). It is a novel cardiotonic agent with antiplatelet activity. It induces apoptosis in HL-60 cells. Acts as an agonist at vanilloid receptors.