Neighborhood

Groups of genes that are frequently observed in each other's genomic neighborhood.

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MOG1

Ran-binding protein Mog1 (191 aa)

Predicted Functional Partners:

RAN1

Ran-like small GTPase; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (223 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

EDO97031

EDO97078

EDO97031

EDO97078

Predicted protein

Predicted protein

0.669

EDO97031

EDP02477

EDO97031

EDP02477

Predicted protein

RAN binding protein, RANBP1

0.824

EDO97031

EDP07056

EDO97031

EDP07056

Predicted protein

Predicted protein

0.547

EDO97031

MOG1

EDO97031

EDP06999

Predicted protein

Ran-binding protein Mog1

0.406

EDO97031

RAN1

EDO97031

EDP04368

Predicted protein

Ran-like small GTPase; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle

0.918

EDO97078

EDO97031

EDO97078

EDO97031

Predicted protein

Predicted protein

0.669

EDO97078

EDO97611

EDO97078

EDO97611

Predicted protein

Predicted protein

0.477

EDO97078

EDP02477

EDO97078

EDP02477

Predicted protein

RAN binding protein, RANBP1

0.824

EDO97078

EDP07056

EDO97078

EDP07056

Predicted protein

Predicted protein

0.547

EDO97078

MOG1

EDO97078

EDP06999

Predicted protein

Ran-binding protein Mog1

0.406

EDO97078

RAN1

EDO97078

EDP04368

Predicted protein

Ran-like small GTPase; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle

0.918

EDO97455

EDP02477

EDO97455

EDP02477

Predicted protein

RAN binding protein, RANBP1

0.824

EDO97455

EDP07056

EDO97455

EDP07056

Predicted protein

Predicted protein

0.547

EDO97455

MOG1

EDO97455

EDP06999

Predicted protein

Ran-binding protein Mog1

0.406

EDO97455

RAN1

EDO97455

EDP04368

Predicted protein

Ran-like small GTPase; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle

0.918

EDO97611

EDO97078

EDO97611

EDO97078

Predicted protein

Predicted protein

0.477

EDO97611

EDP02477

EDO97611

EDP02477

Predicted protein

RAN binding protein, RANBP1

0.824

EDO97611

EDP07056

EDO97611

EDP07056

Predicted protein

Predicted protein

0.547

EDO97611

MOG1

EDO97611

EDP06999

Predicted protein

Ran-binding protein Mog1

0.406

EDO97611

RAN1

EDO97611

EDP04368

Predicted protein

Ran-like small GTPase; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle

0.918

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: