During practice, the Eagles confirmed a report from ESPN that stated Sproles suffered a setback with his lingering hamstring injury on Wednesday. Sproles has missed seven games due to the ailment and appears likely to miss an eighth consecutive game.

Mills missed his second consecutive practice after suffering a foot injury against the Jacksonville Jaguars in Week 8. Despite having the bye week to rest, Mills still has some work to do with his rehabilitation.

Jones hasn't practiced since Week 6 due to the hamstring injury he suffered against the Giants. The Eagles will continue to monitor his status moving forward.

Clement's status will be worth monitoring on Friday. He was a full participant on Wednesday.

In positive news, center Jason Kelce returned to practice after missing Wednesday's session due to a non-injury related issue.

Here are three thoughts on what the potential absences of Sproles, Mills and Jones could mean for the Eagles in Week 10 against the Dallas Cowboys:

1. Sproles could leave the Eagles in an awkward spot at punt returner.

The Eagles have multiple options at punt returner with Sproles sidelined. However, their best option entering the week is now on the Houston Texans. The Eagles felt confident Sproles could return this week, so they cut wide receiver/punt returner DeAndre Carter, who was claimed off waivers by the Texans on Wednesday. The Eagles could hand the job to newly acquired wide receiver Golden Tate but it would open him up to a higher injury risk and more work upon his debut. The team also has Clement who underwhelmed during his few opportunities at the beginning of the season.

2. Mills' potential absence could lead to a make-or-break moment for Rasul Douglas.

With Mills likely to be sidelined in Week 10, the Eagles will need to use Douglas as a starting outside cornerback. While Douglas has flashed when given opportunities, the coaching staff has been hesitant to give him a bigger role in the past. If Douglas plays well against Dallas, the Eagles could be inclined to give him more playing time down the road. If he falters, the Eagles may move on from him being a contributor.

3. It's beginning to sink in that Cre'Von LeBlanc will have a big role on Sunday.

With Jones also out of the lineup, LeBlanc will probably start in his place. LeBlanc was added earlier in the week off waivers. While he has more experience than the player he is replacing, Dexter McDougle, LeBlanc is still new to the defense. Cowboys wide receiver Cole Beasley could be a huge challenge in LeBlanc's Eagles debut.