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Canterbury debutant Kerrod Holland has kicked a goal after the siren to hand the Bulldogs a thrilling 18-16 comeback NRL win over Penrith.

Bulldogs halfback Moses Mbye crashed over on the final play of Thursday night's match, giving the first-gamer a shot to win the game and ruin the Panthers' 50th anniversary celebration.

"Outstanding, mate. I knew it was going over. I knew straight away. It was always going over," Holland said post-game.

Penrith looked headed for their first win of the season when they raced out to a 14-0 lead after just 20 minutes, including a jolting hit from Reagan Campbell-Gillard on Aiden Tolman that set up first points.