... i have been on it now since april and have changed from 8 tablets a week to the injection as i found the sideeffects bad.headaches and sickness being the worse ones.my dose was increased to 20mg injection form an im experiencing the headaches not so much sickness. ... (4 replies)

... well im now on the maximum dose of methetrexate now which is 20mg done by injection at home.i found when i was on 8 tablets the sideeffects where much worse,along with the prednisolone which i was on 10 mg but thank god they are lettin me reduce dose so now i am on 8mg.can only reduce by 1mg a month. ... (21 replies)

... Hi, I'm a newbee here. I've been on Methotextrate for 4 weeks, along with the folic acid daily and 10mg of Prednisone. Started with 3 tablets of 2.5, now up to 6 tablets. I think it has made a difference. I am anxious to get off the prednisone, as it has made a huge size difference. ... (21 replies)

... I have only been taking it for two weeks but the main problem that I have had is sores on the tounge. They are like "lie" bumps on the tounge. I have several of them and they are extremely painful. I am still really tired and don't have a lot of energy but I think that is due to the RA and not the medicine. ... (4 replies)

... I am on methotextrate and, never having been told of possiblie sideeffects, have had no problems with the drug at all. I just took my weekly dose, am now monitoring myself for nausea. ... (21 replies)

... Hi, hang in there. The sideeffects decrease. I have been on MTX for 18 months and I am currently on highest level 20 mg injections. It was rough for the first few months but a great payoff. ... (21 replies)

... Hi everyone
I've just started on Methotextrate and just wanted to ask those of you on it about side-effects.
As the Metho builds up in your body over the weeks, do the side-effects get worse? I've taken my first dose a few days ago, and only have some mild nausea. But I want to know whether this could get worse, or whether that's as bad as it will get.
Please give... (21 replies)

... jennybyc--
tell me what is the cost for injections opposed to pills? will they let you give them to yourself? i would have NO problem doing that and it would make it cheaper. i have been on plaquenil for a year. started on imuran, but got deathly (really) sick. i also take cymbalta for the fibro. she would like me to get off the cymbalta and take a new drug called... (8 replies)

... If you are nervous about the drugs, take a look around this thread and you'll find lots of info about both. I was on the same combination for about 5 years and it was great. Both drugs have long track records of success so don't be scared. ... (8 replies)