Specifically developed for hyposensitive and allergic skin. allergic to standard cosmetics. skin allergy. acute irritation (redness, tightness, itching....). following dermatolical surgery (laser, peels...). Properties; Formulated with the purest ingredients selected for their effectiveness and safety without any potentially irritating additives. Tolerance extreme Cream is the result of two unique and patented processes. Manufactured in a sterile envvironment (E.T.C). Exclusive D.E.F.I.) system protects the formula from contamination after the package is opened. The high conentration of Avene Thermal Spring Water in Tolerance extreme makes it highly hydrating protecting and soothing experience as it revitalises the skin, making it feel better prepared to face daily environmental agressions. Directions for use; Apply morning and evening to face and neck after cleansing with Tolerance extreme Cleansing lotion and soothing with a fine mist of Avene Thermal Spring Water. Tolerance extreme at least one month supply.