The methanol extract from the plant Alstonia scholaris (A.scholaris) was biochemically analyzed for
different bioactive components.LC-MS analysis showed the presence of compounds like lupeol (16%) and
epicatechin (2%). Different biochemical properties of this plant extract were evaluated. It showed antioxidant and
anticancer effect. It showed significant antimicrobial effect also against tested microbes. Antimicrobial activity
against gram positive organisms such as Staphylococcus aureus MTCC 87and gram negative organisms like
Escherichia coli MTTCC 41, Proteus vulgaris 426 (ATCC 6380), Pseudomonas auriginosa 424(ATCC 25619) and
Candida albicans MTTCC 183(ATCC 2091) and found to have significant inhibitory effect. It showed a minimum
inhibitory concentration of 63µg/ml against Staphylococcus aureus. The minimum inhibitory concentration obtained
against the resistant strain Methicillin resistant Staphylococcus aureus was 124µg/ml. The synergistic effect in
combination of the extract with antibiotics also tested and proved to have synergistic effect reducing the MIC value
of the drug to two-fold

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International Journal of Phytotherapy is an international peer-reviewed multidisciplinary journal, scheduled to appear bi-annual and serve as a means for scientific information exchange in the international pharmaceutical forum The International Journal of Phytotherapy publishes.