On Tuesday night, Tijuana will travel to Harrison, New Jersey, as they look to overturn a 2-0 deficit against the Red Bulls. The Xolos need a 0-2 win to send the game to extra time and they need to score at least three to advance outright.

Later that night, Tigres will host Toronto. The universitarios do have an away goal, so they will go through with just a 1-0 win, but if Toronto scores they will need to win by two.

Then on Wednesday, América will visit Panama’s Tauro FC, where they simply need to not lose by 4+ goals in order to reach the semifinals.

Finally, Chivas de Guadalajara will host the Seattle Sounders, needing a 1-0 win to send the series to extra time and a two-goal win to advance outright.