Acinetobacter calcoaceticus baumannii (ACB) is a significant pathogen in hospitals with a growing incidence of multi-drug resistant (MDR) strains. This was a prospective study carried out on ACB isolates from clinical samples between 2013 and 2015. Anti-microbial susceptibility testing was done by Kirby-Bauer Disk Diffusion method (KBBD) method. CRAB strains were tested by Modified Hodge test (MHT) to detect MBL producers. Of the 190 ACB isolates, 142 (75%) were MDR strains. 93% were hospital acquired and 7% community acquired. MDR was seen only in hospital acquired isolates. Acinetobacter was most commonly isolated from ICU (51.41%); followed by medicine ward and surgical wards. 34% of the isolates were from endotracheal tubes which were followed by sputum (14%), pus (13%), blood (10%), suction catheter (7%) and urine (5%). The maximum number of isolates was seen in patients above 60 years of age (28.94%). Among all samples, 120 (63%) were CRAB strains of which 63 out of 120 (53%) were found to be MBL producers by Modified Hodge test (MHT). A high incidence of MDR was seen in ACB from samples of hospitalized patients. MHT is an economical test which can be included in routine testing for detection of MBL phenotypes.