Wolfe appeared unable to put any pressure on his right leg as he was helped by trainers from the cart into the team's facility.

On Thursday, the Broncos lost defensive lineman Billy Winn for the season after he tore his ACL during Thursday's preseason opener against the Chicago Bears.

Wolfe's injury occurred early in the team's 11-on-11 drill.

The Broncos' defense is already without starting outside linebacker Shane Ray for one or two regular season games with a torn right wrist ligament.

Wolfe recorded 51 tackles and 5.5 sacks in 14 games last season.

That performance earned him a four-year extension worth $36.7 million just before the Broncos' victory in Super Bowl 50 over the Carolina Panthers. "We're not sure how bad", coach Vance Joseph said. He was set to rotate with newcomers Domata Peko and Zach Kerr, among others, on the Broncos' rebuilt D-line.