Therapeutic Use:

Indications for FOLLISTIM AQ:

Stimulation of multiple follicles in ovulatory patients undergoing Assisted Reproductive Technologies (ART). Induction of ovulation in patients with functional anovulatory infertility that is not due to ovarian failure.

Adult:

Individualize. ART: initially 150–225 IU daily in the early follicular phase (at least first 4 days), then adjust based on response; max 600 IU. Ovulation induction: initially 75 IU daily for up to 14 days; then adjust weekly by 37.5 IU based on response; max 300 IU. Both: induce final maturation of follicles or ovulation with 5000–10000 IU of hCG (see Precautions).

Warnings/Precautions:

Do complete gynecological and endocrinological exam first. Thromboembolic disorders. Do not give hCG if high estrogen levels or excessive numbers of ovarian follicles by ultrasound indicate a high risk of ovarian hyperstimulation syndrome (OHSS). Nursing mothers: not recommended.