After a lethal virus enters Frank's body, a maverick white blood cell cop and a dutiful cold pill set out to save their host. Presenting a metropolis like setting, the messages of proper health habits and an understanding of the biological workings of the human immune system in this live-action/animated mix is lost amid its over-population of violence, bad attitudes, and body humor.

Why is Osmosis Jones rated PG?

Please read our content details for this movie to help determine if it is suitable for members of your family. We also encourage you to check our full review and our movie information page.

Overall: C After a lethal virus enters Frank’s body, a maverick white blood cell cop and a dutiful cold pill set out to save their host. Presenting a metropolis like setting, the messages of proper health habits and an understanding of the biological workings of the human immune system in this live-action/animated mix is lost amid its over-population of violence, bad attitudes, and body humor.

Violence: C- Live action: man wrestles with monkey, man stumbles up steps, man opens mouth displaying half chewed food, man has green mucous hanging from nose, man vomits, dirty and infected foot shown, teacher bangs on classroom door and hollers at students, puss explodes from pimple, sick and possibly intoxicated man weaves his car across road. Animated action: character shoots gun at other characters, character jumps from helicopter, bacteria characters are chased, cars crash and go off edge of overpass, destruction of property, two saliva characters are killed, monster type figure has sickle-like glowing finger that kills whatever it touches, boat catches on fire, unauthorized use of authority figure’s privileges, angry boss yells at employee, character has fire hose-like arm that freezes anything he shoots, character threatens to bury another in a blackhead, Mafia-like characters agree to help the bad guy after slashing their boss to death (the boss’s mouth still talks while floating on his oozing body parts), characters man guns that shoot at pollen entering the nose, two immune system characters are destroyed, politician kisses child character in wheelchair then recklessly pushes him away, character threatened, characters engage in gambling, sleazy character threatened into giving information, gangster characters plot murder, gangsters attack character with murderous intent, building explodes in flames, character hangs from elevator, two hypothalamus guardian characters killed (the body of one is slumped over desk), character takes hostage then jumps out window, high speed car chase shows cars knocked off road and exploding, characters sneezed out of body, hand to hand combat between characters, one character attempts to choke another, character makes murderous threat, drowning character turns into skeleton and sizzles as flames appear, two characters engage in fist fight and are later shown with bandages and missing teeth, characters fall from burning buildings, city shown in general mayhem.

Sexual Content: B- Live action: Both a monkey and a man are shown scratching their backside, man shown in underwear in school setting, shirtless man shown. Animated action: character looks at centerfold picture of DNA, car impacts billboard displaying picture of bare bum, many female characters depicted as sexy and in short skirts, female character adjusts short skirt, fat female figure is shown in bikini, sexual banter between two characters, character from the wrong side of the digestive track says he “lived on the crack of the lower east backside,” multi-breasted female character dressed in bikini dances in nightclub setting, close-up of another bikini-clad female character, pin-up picture of bikini-clad female figure, couple kiss in theater, mild joke about private body parts and flatulence, female hostage tells captor to watch his hands, male and female characters kiss twice.

Language: B Expletive wordplays on many phrases that sound similar to profanities (e.g., cold pill is called a cheesy as-prin). Many jokes about body parts and functions used to create humor, frequent name-calling. Live action zoo workers shoveling dung are teased. At least four terms of Deity used as expletives.

Alcohol / Drug Use: C- Live action character takes cold pill for his sore throat, which is then depicted in the animated sequences as an action hero fighting germs in the body. Live action: man mentions visit to liquor store and cigarette warehouse, man shown smoking cigar on two occasions, man talks of spending weekend in front of TV with keg, man brings six-pack of beer to friend’s house, man drinks whole can of beer with friend’s encouragement then drives car. Animated action: depiction of bar setting where main character and many background characters shown drinking, character shown hugging bottle.

About author

Donna Gustafson has been involved with her husband Rod's work since the
beginning. Handling many of the behind-the-scenes tasks, she also creates
preview pages for up-coming movies, acts as managing editor and occasionally writes reviews.