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Caspases | Apoptosis | Cell Death | Inflammation

Caspases are a family of cysteine proteases involved in development, cytokine maturation and programmed cell death.

The caspases are made up of two subgroups according to their functions in cell death. Initiator caspases (caspases 2, 8, 9, and 10) are activated through the apoptosis-signaling pathways and activate the caspases 3, 6 and 7 named effector caspases, which carry out programmed cell death.