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The Guava Caspase Assay Suite of fluorescent-based assays for Caspase 3/7, 8, 9 and multi-caspase employ the same protocol making it easier to perform multiple caspase assays in parallel. Further, Guava caspase reagents are membrane permeable allowing one to measure intracellular levels of the enzyme without using harsh lysis methods. The Guava Caspase Assays employ a FLICA (Fluorescent Labeled Inhibitor of Caspase) reagent that specifically identifies active caspases. Each FLICA is comprised of three subunits: