Gabrielli wrote several operas as well as instrumental and vocal church works. He is especially notable as the composer of some of the earliest attested works for solo cello (two sonatas for cello and basso continuo, a group of seven ricercari for unaccompanied cello, and a canon for two cellos). Among his contemporaries, his own virtuoso performances on this instrument earned him the nickname Mingain (or Minghino) dal viulunzeel, a dialect form meaning "Dominic of the cello."