LY2874455

Shipping and handling fee USD40, Free delivery is qualified when the total value of your order exceeds USD500.If the item is temporarily out of stock. Please email to order@pharm-intermediates.com,we will inform you when we have it in stock.

Chemical Information

Product name：LY2874455

Purity：98% min

CAS NO：1254473-64-7

Solubility：10 mM in DMSO

Molecular Formula：C21H19Cl2N5O2

Package：Package according to customer requirements

Molecular Weight：444.314

Storage：Store at -20℃

Quality control

Remarks

LY2874455 is a novel and potent FGF/FGFR Inhibitor. It exhibits a potent activity against FGF/FGFR-mediated signaling in several cancer cell lines and shows an excellent broad spectrum of antitumor activity in several tumor xenograft models representing the major FGF/FGFR relevant tumor histologies including lung, gastric, and bladder cancers and multiple myeloma, and with a well-defined pharmacokinetic/pharmacodynamic relationship.

References

[1] Zhao G, et al. Mol Cancer Ther. 2011, 10(11), 2200-2210.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.