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108 Cards in this Set

: A 12yo patient was treated for a reaction to a bee sting, what drug provides the best coverage of sympathomimetic receptors?

Epinephirine(Alpha1,2 and Beta 1,2)

A 57 yo heart failure pt develops cardiac decompensation, what drug will give you adequate perfusion of his kidneys as well as tx for his Hypotension

Dopamine

A fellow passenger on a Carnival cruise ship looks pale and diaphoretic, what antimuscarinic agent would you give them?

scopolamine

A group of pts are rushed into the ER complaining of excessive sweating, tearing, salivation, HA, N and V, muscle twitching, difficulty breathing and diarrhea. What drug would be the most effective immediate tx

Hemicholinium inhibits the transport of choline into the nerve, thus inhibiting formation of ACh.

How would you reverse the effect of a neuromuscular blocking agent?

Give an anti-chloinesterase - neostigmine, edrophonium, etc

If a patient is given hexamethonium, what would happen to his/her heart rate?

It would increase to ~ 100 beats/min. Both sympathetic and vagal stimulation would be knocked out, but the SA node has an intrinsic pace of 100 beats/min, which is normally checked by vagal stimulation.

Q: Isopoterenol was given to a patient with a developing AV block, why?

A: Stimulates beta adrenergic receptors

Q: Norepi feedbacks and inhibits the presynaptic receptor by what mechanism

A: Binding to the presynaptic alpha 2 release modulating receptors

Q: Reserpine will block the syntheis of this drug and but not its precursor.

A: Blocks Norepi, but not Dopamine

Q: These drugs acts indirectly by releasing strored catecholamines in the presynaptic terminal

A: Amphetamine and Ephedrine

What anticholinesterase crosses the blood-brain-barrier?

physostigmine

Q: What antimuscarinic agent is used in asthma and COPD?

A: Ipratropium

What antimuscarinic drug is useful for the tx of asthma

Ipratropium

What are the classic symptoms of cholinesterase inhibitor poisoning (parathion or other organophosphates)?