Medical Xpress news tagged with:glucagonhttp://medicalxpress.com/
en-usMedical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine.High insulin levels tied to obesity pathway, research showsUT Southwestern Medical Center researchers have identified a crucial link between high levels of insulin and pathways that lead to obesity, a finding that may have important implications when treating diabetes.http://medicalxpress.com/news/2014-08-high-insulin-tied-obesity-pathway.html
Medical researchMon, 25 Aug 2014 17:03:33 EDTnews328204999Glucagon, GLP-1 co-infusion can reduce appetite(HealthDay)—Co-infusion of glucagon and glucagon-like peptide 1 (GLP-1) correlates with a reduction in appetite, and GLP-1 protects against glucagon-induced hyperglycemia in healthy volunteers, according to a study published online June 17 in Diabetes.http://medicalxpress.com/news/2014-06-glucagon-glp-co-infusion-appetite.html
DiabetesWed, 25 Jun 2014 17:46:08 EDTnews322937156Scientists identify third critical hormone in Type 2 diabetes(Medical Xpress)—Working with mice and human blood and liver samples, scientists from the Johns Hopkins Children's Center have identified a previously unsuspected liver hormone as a critical player in the development of type 2 diabetes, a condition that affects nearly 26 million people in the United States and is a leading cause of heart disease and stroke, as well as kidney, nerve and eye damage.http://medicalxpress.com/news/2014-04-scientists-critical-hormone-diabetes.html
DiabetesThu, 03 Apr 2014 09:12:12 EDTnews315735114A healthy side effect of diabetes drug(Medical Xpress)—New research has shown the promising potential of a glucose-regulating drug to improve the condition of arteries for diabetes sufferers, possibly protecting them against heart attack or stroke.http://medicalxpress.com/news/2013-09-healthy-side-effect-diabetes-drug.html
DiabetesMon, 23 Sep 2013 08:01:23 EDTnews299142073Amino acid with promising anti-diabetic effectsNew experiments conducted by researchers from the University of Copenhagen show that the amino acid arginine – found in a wide variety of foods such as salmon, eggs and nuts – greatly improves the body's ability to metabolise glucose. Arginine stimulates a hormone linked to the treatment of type 2 diabetes, and works just as well as several established drugs on the market. The research findings have just been published in the scientific journal Endocrinology.http://medicalxpress.com/news/2013-09-amino-acid-anti-diabetic-effects.html
Medical researchMon, 09 Sep 2013 13:23:37 EDTnews297951797Appetite hormone misfires in obese peopleGlucagon, a hormone involved in regulating appetite, loses its ability to help obese people feel full after a meal, but it continues to suppress hunger pangs in people with type 1 diabetes, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).http://medicalxpress.com/news/2013-08-appetite-hormone-misfires-obese-people.html
Overweight and ObesityTue, 20 Aug 2013 13:35:06 EDTnews296224496Antipsychotics induce insulin resistance without weight gain(HealthDay)—Atypical antipsychotic drugs induce insulin resistance even in the absence of weight gain and mechanisms regulating eating behavior, according to a study published online July 8 in Diabetes.http://medicalxpress.com/news/2013-07-antipsychotics-insulin-resistance-weight-gain.html
DiabetesThu, 18 Jul 2013 16:00:01 EDTnews293378780Scientists find 3D structure of key drug target for diabetesAn international team led by scientists at The Scripps Research Institute (TSRI) has determined and analyzed the three-dimensional atomic structure of the human glucagon receptor. The receptor, found mainly on liver and kidney cells, helps regulate glucose levels in the bloodstream and is the target of potential therapeutic agents for type 2 diabetes.http://medicalxpress.com/news/2013-07-scientists-3d-key-drug-diabetes.html
Medical researchWed, 17 Jul 2013 13:00:06 EDTnews293280066Type 1 diabetes: Can insulin-producing cells be regenerated?(Medical Xpress)—Patrick Collombat, Inserm Research Director and head of the Avenir team at the Institut de Biologie Valrose in Nice, has published new results concerning Type I diabetes. Researchers show that, in mice, the pancreas contains cells capable of being converted into insulin-producing β cells, something that can be done at any age. They also demonstrate that all pancreatic β cells can be regenerated several times and that chemically-induced diabetes in mice can thus be "treated" repeatedly. The challenge for the researchers is now to show that these procedures can be applied to humans.http://medicalxpress.com/news/2013-06-diabetes-insulin-producing-cells-regenerated.html
DiabetesThu, 27 Jun 2013 13:00:01 EDTnews291556474Adjustable gastric banding more effective when combined with gastrointestinal hormone GLP-1Pharmacological activation of the receptor for glucagon-like peptide 1 (GLP-1) in conjunction with adjustable gastric banding (AGB) surgery may improve weight loss outcomes achieved with this procedure when compared to performing AGB alone, say researchers from the University of Cincinnati (UC) and the Helmholtz Center in Munich, Germany.http://medicalxpress.com/news/2013-06-adjustable-gastric-banding-effective-combined.html
DiabetesThu, 20 Jun 2013 06:39:21 EDTnews290929153DNA variant affects diabetes risk and treatment responseA DNA variant near a digestive enzyme does not only affect risk of developing diabetes but also affects the response to treatment, an international consortium of researchers including the University of Dundee has found.http://medicalxpress.com/news/2013-05-dna-variant-affects-diabetes-treatment.html
DiabetesFri, 17 May 2013 08:10:03 EDTnews287996295New treatment may lead the way to fighting obesity and diabetesTwo professors believe they may have a promising lead from which to develop a new treatment for obesity and diabetes.http://medicalxpress.com/news/2013-04-treatment-obesity-diabetes.html
Overweight and ObesityThu, 25 Apr 2013 07:35:54 EDTnews286094146Research suggests popular diabetes drugs can cause abnormal pancreatic growth in humans(Medical Xpress)—Individuals who had taken a type of drug commonly used to treat Type 2 diabetes showed abnormalities in the pancreas, including cell proliferation, that may be associated with an increased risk of neuroendocrine tumors, according to a new study by researchers from UCLA and the University of Florida. Their findings were published online March 22 in the journal Diabetes.http://medicalxpress.com/news/2013-03-popular-diabetes-drugs-abnormal-pancreatic.html
DiabetesWed, 27 Mar 2013 07:27:52 EDTnews283588058Diabetic medication may protect patients from developing heart failure, study findsA class of medications commonly prescribed to lower blood sugar in diabetic patients appears to protect them from developing heart failure, according to a study at Henry Ford Hospital in Detroit.http://medicalxpress.com/news/2013-03-diabetic-medication-patients-heart-failure.html
CardiologySun, 10 Mar 2013 12:53:17 EDTnews282138790High-fat diet impairs satiation signaling in obese-prone(HealthDay)—Feeding obese-prone rats a high-fat diet leads to impaired satiation signaling through glucagon-like peptide-1 (GLP-1), a gastrointestinal hormone that suppresses food intake and helps regulate energy balance, according to a study published online Feb. 19 in Diabetes.http://medicalxpress.com/news/2013-02-high-fat-diet-impairs-satiation-obese-prone.html
DiabetesWed, 27 Feb 2013 15:40:01 EDTnews281200420Risk of pancreatitis doubles for those taking new class of diabetes drugsPeople who take the newest class of diabetes drugs to control blood sugar are twice as likely as those on other forms of sugar-control medication to be hospitalized with pancreatitis, Johns Hopkins researchers report.http://medicalxpress.com/news/2013-02-pancreatitis-class-diabetes-drugs.html
MedicationsMon, 25 Feb 2013 16:00:07 EDTnews281009581Study suggests glucagon-like peptide-1 receptor agonists related to adolescent weight lossPreliminary evidence from a clinical trial suggests that treatment with glucagon-like peptide-1 (GLP-1) receptor agonists was associated with reduced body mass index and body weight in adolescents with severe obesity, according to a report published Online First by JAMA Pediatrics.http://medicalxpress.com/news/2013-02-glucagon-like-peptide-receptor-agonists-adolescent.html
PediatricsMon, 04 Feb 2013 16:00:12 EDTnews279197910Bile acid sequestrant reduces glucose concentration in T2DM(HealthDay)—For patients with type 2 diabetes taking metformin monotherapy, the bile acid sequestrant colesevelam reduces fasting and postprandial glucose concentrations without any effects on insulin concentration, secretion, or action, according to research published online Dec. 18 in Diabetes.http://medicalxpress.com/news/2013-01-bile-acid-sequestrant-glucose-t2dm.html
DiabetesWed, 30 Jan 2013 16:10:01 EDTnews278781849Study: Most-used diabetes drug works in different way than previously thoughtA team, led by senior author Morris J. Birnbaum, MD, PhD, the Willard and Rhoda Ware Professor of Medicine, with the Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, found that the diabetes drug metformin works in a different way than previously understood. Their research in mice found that metformin suppresses the liver hormone glucagon's ability to generate an important signaling molecule, pointing to new drug targets. The findings were published online this week in Nature.http://medicalxpress.com/news/2013-01-most-used-diabetes-drug-previously-thought.html
DiabetesSun, 06 Jan 2013 13:00:31 EDTnews276685322Teduglutide seems effective, safe for short bowel syndrome(HealthDay)—For patients with short bowel syndrome with intestinal failure (SBS-IF), the glucagon-like peptide 2 analogue teduglutide appears to be safe and reduces the number of days off parenteral support, according to a phase 3 study published in the December issue of Gastroenterology.http://medicalxpress.com/news/2012-12-teduglutide-effective-safe-short-bowel.html
Diseases, Conditions, SyndromesWed, 12 Dec 2012 13:30:01 EDTnews274540602New findings on glucagon synthesisResearchers at Karolinska Institutet in Sweden have shown that the cells that produce glucagon are stimulated by the hormone itself. A previous study by the same group demonstrated that this principle also applies to insulin. This means that a feedback system is at work in the body, whereby hormone secreting cells receive an immediate signal to produce more of the hormone.http://medicalxpress.com/news/2012-12-glucagon-synthesis.html
Medical researchMon, 03 Dec 2012 15:00:10 EDTnews273755404Doubling down against diabetes: Turbo-charged gut hormonesA collaboration between scientists in Munich, Germany and Bloomington, USA may have overcome one of the major challenges drug makers have struggled with for years: Delivering powerful nuclear hormones to specific tissues, while keeping them away from others.http://medicalxpress.com/news/2012-11-diabetes-turbo-charged-gut-hormones.html
Medical researchTue, 13 Nov 2012 11:27:54 EDTnews272028400Joslin researchers gain new understanding of diabetes and kidney diseaseScientists at Joslin Diabetes Center have identified biological mechanisms by which glucagon-like peptide-1 (GLP-1), a gut hormone, protects against kidney disease, and also mechanisms that inhibit its actions in diabetes. The findings, which are reported today online by Diabetes, may lead to the development of new therapeutic agents that harness the actions of GLP-1 to prevent the harmful effects of hyperglycemia on renal endothelial cells.http://medicalxpress.com/news/2012-07-joslin-gain-diabetes-kidney-disease.html
Diseases, Conditions, SyndromesMon, 23 Jul 2012 10:27:42 EDTnews262258055Physical activity needed in order to reap benefits of dietary restrictionFruit flies on dietary restriction (DR) need to be physically active in order to get the lifespan extending benefits that come from their Spartan diet. If the same axiom holds true in humans, those practicing caloric restriction in hopes of living longer need to make sure they eat enough to avoid fatigue.http://medicalxpress.com/news/2012-07-physical-reap-benefits-dietary-restriction.html
Medical researchMon, 02 Jul 2012 12:00:02 EDTnews260448824Absolute incretin effect reduced in type 2 diabetes(HealthDay) -- For patients with type 2 diabetes mellitus (T2DM) the absolute incretin effect is reduced compared with healthy individuals, but its relative importance is increased, particularly in first-phase insulin secretion, according to a study published online June 20 in Diabetes.http://medicalxpress.com/news/2012-06-absolute-incretin-effect-diabetes.html
DiabetesMon, 25 Jun 2012 14:35:04 EDTnews259853673Gut hormone receptor in brain is key to gastric emptying rate; may help prevent obesityResearchers have discovered how a hormone in the gut slows the rate at which the stomach empties and thus suppresses hunger and food intake. Results of the animal study will be presented at The Endocrine Society's 94th Annual Meeting in Houston.http://medicalxpress.com/news/2012-06-gut-hormone-receptor-brain-key.html
Overweight and ObesityMon, 25 Jun 2012 13:30:01 EDTnews259847813Early loss of glucagon response to hypoglycemia found in teens(HealthDay) -- In adolescents with type 1 diabetes the glucagon response to hypoglycemia is lost as early as one month and at a median of eight months after diabetes diagnosis, according to a study published online June 14 in Diabetes Care.http://medicalxpress.com/news/2012-06-early-loss-glucagon-response-hypoglycemia.html
DiabetesFri, 22 Jun 2012 11:30:01 EDTnews259577602New inflammation hormone link may pave way to study new drugs for Type 2 diabetesA new link between obesity and type 2 diabetes found in mice could open the door to exploring new potential drug treatments for diabetes, University of Michigan Health System research has found.http://medicalxpress.com/news/2012-05-inflammation-hormone-link-pave-drugs.html
DiabetesTue, 15 May 2012 13:41:04 EDTnews256308049Targeting glucagon pathway may offer a new approach to treating diabetesMaintaining the right level of sugar in the blood is the responsibility not only of insulin, which removes glucose, but also of a hormone called glucagon, which adds glucose.http://medicalxpress.com/news/2012-04-glucagon-pathway-approach-diabetes.html
DiabetesThu, 12 Apr 2012 12:00:17 EDTnews253443358Study finds molecular switch that controls liver glucose production, may offer target for type II diabetes therapyIn their extraordinary quest to decode human metabolism, researchers at the Salk Institute for Biological Studies have discovered a pair of molecules that regulates the liver's production of glucose -- the simple sugar that is the source of energy in human cells and the central player in diabetes.http://medicalxpress.com/news/2012-04-molecular-liver-glucose-production-ii.html
Medical researchSun, 08 Apr 2012 13:00:29 EDTnews253084650