The BrainSpan atlas is a foundational resource for studying
transcriptional mechanisms involved in human brain development.

Consortium Members

The BrainSpan atlas was developed by a consortium consisting of the Allen Institute for Brain Science; Yale University (Nenad Sestan, Mark B. Gerstein); the Zilkha Neurogenetic Institute of the Keck School of Medicine of the University of Southern California (James A. Knowles, Pat Levitt); the Athinoula A. Martinos Center at Massachusetts General Hospital/Harvard Medical School and MIT HST/CSAIL (Bruce Fischl); the University of California, Los Angeles (Daniel H. Geschwind); and the University of Texas Southwestern Medical Center (Hao Huang), with strong collaborative support from the Genes, Cognition and Psychosis Program, which is part of the Intramural Research Program of NIMH, NIH (Thomas M. Hyde, Joel E. Kleinman, Daniel R. Weinberger).

Funding Support

This project was supported by Award Numbers RC2MH089921 (PIs: Ed Lein & Michael Hawrylycz, Allen Institute
for Brain Science), RC2MH090047 (PI: James A. Knowles, University of Southern California) and RC2MH089929
(PI: Nenad Sestan, Yale University) from the National Institute of Mental Health. The content is solely the
responsibility of the respective authors and does not necessarily represent the official views of the
National Institute of Mental Health or the National Institutes of Health.

CONTRIBUTORS

IN ASSOCIATION WITH

Data Overview

The BrainSpan atlas includes the following

Developmental Transcriptome:
RNA sequencing and exon microarray data
profiling up to sixteen cortical and subcortical structures across the full course of human brain development.