Ion PGM™ System Featured Customer Stories

Dr. Guilherme Oliveira on using the Ion PGM™ and a multitude of applications including gene panel sequencing with Ion AmpliSeq™ Panels and metagenomic applications

Dr. Guilherme Oliveira, of the Genomics and Computational Biology Group in Brazil, discusses his work with the Ion PGM™ Sequencer and Ion AmpliSeq™ Panels in a wide variety of research areas, including metagenomics, de novo sequencing of bacterial genomes, transcriptomics and infectious and parasitic diseases.

Dr. Marcel Nelen and Dr. José Carlos Machado discuss the development of the Ion AmpliSeq™ BRCA 1&2 Community Panel for clinical research. The panel, designed to screen mutations in the genes' coding regions, was developed by Drs. Marjolijn Ligtenberg and Arjen Mensenkamp of the Nijmegen Medical Center and Drs. José Carlos Machado and Jose Luis Costa of IPATIMUP. Dr. Machado discusses how Ion Torrent® has enabled his lab to study more genes, more quickly, than using previous methods. Leading scientists collaborate to create Ion AmpliSeq™ Community panels, which are then made available to the larger community.

Audrey Papp, the technical director for the Program in Pharmacogenomics at Ohio State University, discusses her preliminary data using the new Ion AmpliSeq™RNA Panels in an autism experiment. Papp said the panels yielded the most accurate allelic expression data she has seen.

Dr Seibold's lab recently used the Ion Personal Genome Machine® and Ion AmpliSeq™ RNA panels for an asthma biomarker project to help identify genetic determinants and biomarkers of complex lung diseases, including asthma and pulmonary fibrosis.

Rapid innovation and flexibility of the PGM™ and Proton™ Sequencers drives the cancer genome research laboratory into the future

Mr. Joseph Boland has been working at the Cancer Genomics Research Laboratory (CGR) at the National Cancer Institute for the past 4.5 years. During the first 4 years, Mr. Boland was tasked with the creation and operation of the Development and Sequencing Operations laboratory. His laboratory is tasked with evaluating new sequencing technologies and rigorous validation testing before transfer to the groups within the Cancer Genomics Research Laboratory.

Total RNA transcript analysis on the Ion Torrent™ platform: insight into functional ncRNA in cancer

Dr. Timothy Triche is the Director for the Children's Hospital Los Angeles Center for Personalized Medicine. He previously served as Chief of the Department of Pathology and Laboratory Medicine for over 20 years. He is also Professor of Pathology and Pediatrics at the Keck School of Medicine of the University of Southern California.

Implementing and Applying Ion Torrent™ Technology at the Broad Institute

Chad Nusbaum has been the co-director of the Genome Sequencing and Analysis Program at the Broad Institute since 2001. In 2012 he was appointed founding Scientific Director of the new Broad Technology Labs, an innovation incubator for the Institute.

On Top of Outbreaks - Rapid PGM™ Sequencing To Advance Clinical and Public health Microbiology

Dr. Dag Harmsen is an MD specialized in Clinical Microbiology and Infectious Diseases Epidemiology. His scientific interests focus around molecular diagnostics, epidemiology, and phylogeny of micro-organisms. However, he is best known for delivering applied microbiology bioinformatics solutions, like the Ridom SpaServer for MRSA typing. He published the first study that applied the Bruker MALDI ToF MS system in microbiological diagnostics.

The Evolution of Ion Semiconductor Sequencing

Donna Muzny has been the Director of Operations at the Baylor College of Medicine Human Genome Sequencing Center (HGSC) since 2004. Ms. Muzny has more than 25 years of experience in sequencing chemistry and technical development. She has been instrumental in establishing the Center's production groups and finishing pipelines, and delivering the high standard of sequence quality at the HGSC. Ms. Muzny has focused on the establishment of the NexGen sequencing pipelines for all commercially available instruments.

Ion World 2012

Watch presentations from speakers at Ion World 2012 discussing advancements on and applications of the Ion PGM™ System, as well as their experiences with the data and performance of the Ion Proton™ System.