To date, a total of eight studies have pointed to the protective effects of melatonin and vitamins C and E in stemming the damage caused by cell phone emissions. In particular, these agents show promise in averting the increased oxidative stress that is thought to contribute to an increased risk of certain cancers.

These studies have unveiled statistically significant protective effects of melatonin and vitamins C and E against the effects of the radiation frequency at which cell phones emit and receive radio frequency radiation.

Six of these eight studies were controlled, short-term studies (ranging from 10-30 days) in rodents. Each study examined 24-30 subjects. Study subjects were divided equally into three groups: one group received radiation exposure; another received active treatment with melatonin only, vitamin C only, or vitamins C and E before radiation exposure; and a control group did not receive radiation or active treatment.

After the treatment period, scientists examined skin sections for radiation injury and analyzed blood and urine for markers of oxidative stress. They found significant kidney damage, skin changes, oxidative stress, and fibrosis in the animals who received radiation exposure only. Remarkably, these effects were reversed in the groups that received melatonin 13-16 and vitamins C17,18 and E.17

Another two controlled studies in rodents, one of 10 days'19 and another of 60 days' duration,20 revealed that melatonin significantly protects against retinal (eye)20 and kidney tissue 19 damage caused by cell phone radiation, as compared with subjects that did not receive melatonin.

Despite this compelling evidence, other avenues of research still need to be pursued after contradictory findings from seven different studies that have looked into the effect of cell phone radiation on melatonin levels in the body increased cell phone use and decreasing melatonin levels in the blood.21

Yet six other studies--two in humans22,23 and four in rodents24-27-- found that melatonin levels remained unchanged after radiation exposure. One human study did suggest that cell phone radiation may impact melatonin onset time. These were small studies, however, the majority of which were less than 28 days' duration.

Melatonin is a vital natural neurohormone (hormone secreted by or acting on a part of the nervous system) that acts as a potent free radical scavenger and antioxidant. Melatonin regulates the daily circadian rhythm and is essential to self-repair and regeneration.

Given melatonin's protective effects, these findings warrant further research into the effect of cell phone radiation on melatonin in larger, longer-term, well-controlled human studies.