Details

Gleevec 100mg Tablet is indicated in the treatment of children/adolescents and adults who have acute lymphoblastic leukemia with Philadelphia chromosome positive (Ph-positive ALL) and chronic myeloid leukemia (CML).

ALL and CML are types of leukemia in which an abnormal chromosome produces an enzyme that causes an unrestrained growth of WBCs. Generic Imatinib is present in Gleevec 100mg anticancer medicine as chief active constituent. Gleevec leaves the normal cells while kill the abnormal cells. Gleevec 100mg tablets can also be indicated in the treatment of adults for myeloproliferative disease (MPD) or myelodysplastic disease (MDS). These are a group of blood disorders in which some blood cells begin to grow uncontrollably. Gleevec 100mg tablets can also be used to treat gastrointestinal stromal tumors (GIST).

Under What Conditions The Use of Gleevec 100mg Tablet Is Contraindicated?

Kidney or liver problems.

You have had your thyroid gland removed.

Heart problems.

Hepatitis B infection.

Which Other Medications Interact With Gleevec 100mg Tablets?

Antifungal drugs like Itraconazole, Ketoconazole

Antiviral medications

Cyclosporin

Antidepressants

Cholesterol lowering drugs such as Simvastatin

Antibiotics such as Erythromycin, Rifampicin, Clarithromycin

Steroids like Dexamethasone

Anticonvulsants such as Phenytoin, Carbamazepine

Blood thinners such as Warfarin

What Are The Recommended Doses of Gleevec Tablets?

For CML, the normal adult dose of Gleevec is 400 to 600mg taken orally daily and the daily maximum dose is 800mg. The dose is based on what stage of CML you have.

For Ph-positive ALL, the normal adult dose of Gleevec is 600mg taken orally daily.

For MDS/MPD, the initial dose of Gleevec is 400mg.

For GIST, the normal dose of Gleevec is 400mg or 600mg taken via oral route daily.

Gleevec tablet is generally taken as a single dose every day. On the other hand, your physician may want you to take this medication in two doses, one in the morning and other one in the evening.

How Should Gleevec 100mg Tablets Be Stored?

Gleevec 100mg tablets should be stored at room temperature away from heat, light or moisture. Protect your Gleevec 100mg tablets from the reach of children and pets.

What happens in case of missed dose?

The missed dose should be taken the moment you remember about it, and then carry on with your usual dosing plan. Avoid taking a double dose of Gleevec 100mg to make up for the missed dose. This may add to the possibility of getting an unnecessary side effect.

What happens in case of overdose?

In case of overdosing, you must contact your nearby doctor or local poison control center immediately.

What Are The Side Effects That May Crop Up While Using Gleevec 100mg Tablets?

Common side effects associated with this medication include nausea, vomiting, dizziness, dry mouth, changes in appetite and weight, weakness, pain in the bones, breast enlargement, numbness, tingling or coldness in fingers and toes. In case you experience any of these side effects, then consult your doctor before they persist.

What Are The Precautionary Measures That Should Be Followed While Using Gleevec 100mg Tablets?

Avoid the intake of grapefruit juice while you are being treated with Gleevec 100mg tablets.

Do not carry out any heavy physical task while taking Gleevec 100mg tablets.