RT Journal
A1 HATCHER RA, BAILEY HC
T1 TIncture of strophanthus and strophanthin
JF Journal of the American Medical Association
JO Journal of the American Medical Association
YR 1909
FD January 2
VO LII
IS 1
SP 5
OP 10
DO 10.1001/jama.1909.25420270005001a
UL http://dx.doi.org/10.1001/jama.1909.25420270005001a
AB The pharmacology of strophanthus indicates that it has certain advantages over digitalis, and careful clinical observation has sustained the view of pharmacologists that it has a distinct field of usefulness. It is a fact, however, that the average practitioner either refuses to employ strophanthus at all, or, after a brief trial, dismisses it and returns to digitalis.We believe that the reasons for this state of affairs can be explained satisfactorily, and that the chief causes militating against the proper use of strophanthus can be removed.One of the principal causes of the disrepute into which strophanthus fell was the utter unreliability of the tincture because of extreme variability in the strength of the seed, according to the testimony of several German investigators. It has been shown1 that the tincture of strophanthus made by the large manufacturing houses of the United States is surprisingly uniform in potency—much more nearly