Miloslav Gabris, Ceske Budejovice CZ

Patent application number

Description

Published

20100119387

DEVICE FOR SUPPLYING FUEL - Devices for supplying fuel are already known, having a supply unit which has a pump housing connected to an electrical ground and is supported on a pump mount. It is disadvantageous that during operation, the pump mount can become electrostatically charged and has no device for electrostatic discharging during operation.

05-13-2010

20100186194

HOLDING ELEMENT FOR HOLDING AN ASSEMBLY IN A HOLDER, AND FASTENING ARRANGEMENT - Holding elements are known for holding an assembly in a holder, comprising a holding section for engaging behind the assembly and holding members that are provided on the holding section for holding the assembly in the holder. It is disadvantageous that the holding element is comparatively expensive to produce. For example, it is configured very rigidly in the holding direction, which is achieved with a comparatively high amount of material. This results in high production costs. In addition, in the case of very high mechanical loads the detent connection can detach due to torque acting on the detent hooks. The holding element according to the invention is simplified, thereby lowering the production costs. According to the invention, the holding section has a flat configuration viewed in the holding direction, and the holding members are angled in relation to the holding section and configured as elastically resilient holding arms.

07-29-2010

20100200595

FUEL DELIVERY MODULE - Fuel delivery modules are already known having a tank flange and having an accumulator pot which is connected to the tank flange by means of at least one guide rod and which is mounted so as to be axially movable along the guide rod, where the guide rod is pressed with one end into a receptacle of the tank flange. It is disadvantageous that the receptacle is expanded over the entire longitudinal extent as the guide rod is pressed in. As a result of tolerance fluctuations in production, excessively high pressures can occur in the receptacle here, which pressures can cause cracks in the receptacle. This leads to rejects and therefore to high production costs. In the fuel delivery module according to the invention, damage to the receptacle during assembly is prevented. According to the invention, it is provided that that end of the guide rod which faces toward the tank flange has a bead, which interacts in a retentive manner with the receptacle, and a constriction situated behind the bead in a direction facing away from the tank flange.

08-12-2010

20110168723

RESERVOIR FOR A FUEL TANK - Reservoirs for fuel tanks, which can be filled via an opening that can be closed by a closing element, are already known. Such a closing element interacts with a sealing seat and is arranged on a bearing that is located in the region of the opening and is fixed to an edge area of the opening by at least two struts. In prior art, the opening, with the bearing and the struts, is often produced as a single-piece together with the reservoir and the base by injection moulding. A disadvantage thereof is that the struts can undergo material shrinkage during production, which leads to a tension of the struts between the edge area of the opening and the bearing. This can lead to an irregular deformation and hence to an uneven sealing seat, so that the closing element does not seal in a tight manner and that the valve has a leak. In the reservoir according to the invention, the sealing of the opening is improved by at least one strut not having a rectilinear form, thus obtaining elastic expansion compensation.

07-14-2011

20120018019

DEVICE FOR DELIVERING FUEL - Devices for delivering fuel are already known, comprising a suction jet pump that is arranged in a storage crucible and has a nozzle and a mixer duct provided downstream of the nozzle and arranged perpendicular to the bottom of the storage crucible, wherein at the outlet of the mixer duct an impingement means is arranged, against which the jet of the nozzle impinges in the substantially unfilled mixer duct, and in doing so is at least partially returned into the mixer duct. It has been found that despite the impingement means the propulsive jet tends to eject the liquid column present in the mixer duct. As soon as the liquid level in the storage crucible has decreased below the outlet of the mixer duct, no more fuel can replenish from above into the mixer duct so that the mixer duct may be unfilled after switching off the suction jet pump. Upon restarting the suction jet pump, an unsatisfying high delay until suction of the suction jet pump occurs, because the volume of the propulsive jet must first fill the mixer duct in order to create a vacuum and suction power. Using the device according to the invention, a pushing out of the liquid column of the mixer duct by the propulsive jet of the suction jet pump is avoided. Thus the lead time of the suction jet pump is approximately equal in all operating states. According to the invention, an additional volume (

01-26-2012

Patent applications by Miloslav Gabris, Ceske Budejovice CZ

Miloslav Haluza, Ivancice CZ

Patent application number

Description

Published

20150224577

METHOD OF PREPARATION OF MAGNETICALLY CONDUCTIVE POWDERS BY CAVITATION AND DEVICE TO CARRY OUT THE METHOD - A method of preparing magnetically conductive powders based on principle of liquid flow control in a cavitation line, where in a jet tube are evoked, during the rise of a cavitation cloud and implosion of cavitation bubbles with intensity up to ultrasound frequency 24 kHz, pulse shock waves acting on a surface of a substance whereby are released particles in dimensions in range of micrometer or nanometer units. Particles of the substance from a jet tube are carried away by liquid media into a header where they are captured via a magnetic element. A device includes a cavitation line that is equipped for capture of decavitated particles of the substance by at least one header along which is placed a magnetic element.

08-13-2015

Miloslav Hula, Krivoklat CZ

Patent application number

Description

Published

20100310254

DEVICE FOR MULTICAST OF OPTICAL SIGNALS IN THE INTERNET AND OTHER NETWORKS - Device for multicast of optical signals in the Internet and other networks is formed by an electronic part and an optical part. The electronic part consists of a control module, an interface module formed by a power supply block, a block for measuring basic operational parameters of the whole device and an interface, and by a power supply part. The power supply block of the interface module is connected to the power supply part, to the optical part and to the control module. The interface is connected to the optical part and to the control module, and the block for measuring basic operational parameters of the whole device is connected to the power supply part and to the control module. Input/output interfaces involving a standard interface for communication with a user and/or an interface for communication in an Ethernet network and/or an interface via RS 232 and/or an interface for communication via a serial USB bus are connected to the control module. The optical part of the device is designed as a double-stage with a first stage formed by M passive wide-spectrum optical splitters, each of which is equipped with N outputs and a second stage is realized by N wide-spectrum optical switches, each of which is equipped with M inputs.

12-09-2010

20130148960

MODULAR KIT OF DEVICES FOR VARIABLE DISTRIBUTION, MIXING AND MONITORING OF OPTICAL SIGNALS IN THE INTERNET AND OTHER NETWORKS - Modular kit of devices for variable distribution, mixing and monitoring of optical signals in the Internet and other networks is formed by an optical module interconnected with a control electronic module of the electronic system with two redundant power supply sources, which is subsequently interconnected with the communication computer module equipped with the user communication interface and the machine communication interface. Optical module has N optical inputs and M optical outputs where N and M are non-zero natural numbers, and in total the optical module contains N×M of 2×2 type Mach-Zender interferometer optical switching elements. Each of them has two optical inputs, two optical outputs and one electric input. Optical switching elements are mutually interconnected in a grid. Control electronic module is formed by N×M pulse-width modulators connected via an interface module to the communication computer module and to the power supply distribution block.

06-13-2013

Miloslav Hùla, Krivoklat CZ

Patent application number

Description

Published

20130148960

MODULAR KIT OF DEVICES FOR VARIABLE DISTRIBUTION, MIXING AND MONITORING OF OPTICAL SIGNALS IN THE INTERNET AND OTHER NETWORKS - Modular kit of devices for variable distribution, mixing and monitoring of optical signals in the Internet and other networks is formed by an optical module interconnected with a control electronic module of the electronic system with two redundant power supply sources, which is subsequently interconnected with the communication computer module equipped with the user communication interface and the machine communication interface. Optical module has N optical inputs and M optical outputs where N and M are non-zero natural numbers, and in total the optical module contains N×M of 2×2 type Mach-Zender interferometer optical switching elements. Each of them has two optical inputs, two optical outputs and one electric input. Optical switching elements are mutually interconnected in a grid. Control electronic module is formed by N×M pulse-width modulators connected via an interface module to the communication computer module and to the power supply distribution block.

06-13-2013

Miloslav Karhanek, Santa Cruz, CA US

Patent application number

Description

Published

20100072080

Functionalized Nanopipette Biosensor - Disclosed are methods and devices for biomolecular detection, comprising a nanopipette, exemplified as a hollow inert, non-biological structure with a conical tip opening of nanoscale dimensions, suitable for holding an electrolyte solution which may contain an analyte such as a protein biomolecule to be detected as it is passed through the tip opening. Biomolecules are detected by specific reaction withy peptide ligands chemically immobilized in the vicinity of the tip. Analytes which bind to the ligands cause a detectible change in ionic current. A sensitive detection circuit, using a feedback amplifier circuit, and alternating voltages is further disclosed. Detection of Il-10 at a concentration of 4 ng/nl is also disclosed, as is detection of VEGF.

03-25-2010

20100261619

Charge Perturbation Detection System for DNA and Other Molecules - Methods and apparatus for direct detection of chemical reactions are provided. In a preferred embodiment, electric charge perturbations of the local environment during enzyme-catalyzed reactions are sensed by an electrode system with an immobilized target molecule. The target molecule is preferably DNA. The charge perturbation caused by the polymerase reaction can uniquely identify a DNA sequence. The polymerization process generates local perturbations of charge in the solution near the electrode surface and induces a charge in a polarazible gold electrode. This event is detected as a transient current by a voltage clamp amplifier. Detection of single nucleotides in a sequence can be determined by dispensing individual dNTPs to the electrode solution and detecting the charge perturbations. Alternatively, multiple bases can be determined at the same time using a mix of all dNTPs with subsequent analysis of the resulting signal. The initial enzyme attachment to the DNA molecule can be detected prior to polymerization, with electrode capacitance measurement using the same voltage-clamp amplifier. This technique and device may be adapted to other reaction determinations, such as enzymatic reactions, other electrode configurations, and other amplifying circuits.

10-14-2010

20110020806

Rapid DNA Sequencing by Peroxidative Reaction - Disclosed is a method of polynucleic acid (e.g., DNA) sequencing which is based on the generation of pyrophosphate (PPi) that occurs when a complementary base is incorporated into a growing DNA strand being synthesized on a template. The method utilizes a cascade of enzymatic reactions catalyzed by hypoxanthine-phosphoribosyl transferase, xanthine oxidase, and peroxidase in addition to DNA polymerase and apyrase. The last chemical step in the cascade of reactions is the oxidation of a material such as an electrode or luminol by hydrogen peroxide. This generates a detectable electrical or optical signal. This method is independent of luciferase, does not require dATP analogue, and is intended to improve precision and sensitivity of DNA sequencing, and to lessen the unsynchronized polymerization.

01-27-2011

20110281739

Charge Perturbation Detection System for DNA and Other Molecules - Methods and apparatus for direct detection of chemical reactions are provided. In a preferred embodiment, electric charge perturbations of the local environment during enzyme-catalyzed reactions are sensed by an electrode system with an immobilized target molecule. The target molecule is preferably DNA. The charge perturbation caused by the polymerase reaction can uniquely identify a DNA sequence. The polymerization process generates local perturbations of charge in the solution near the electrode surface and induces a charge in a polarazible gold electrode. This event is detected as a transient current by a voltage clamp amplifier. Detection of single nucleotides in a sequence can be determined by dispensing individual dNTPs to the electrode solution and detecting the charge perturbations. Alternatively, multiple bases can be determined at the same time using a mix of all dNTPs with subsequent analysis of the resulting signal. The initial enzyme attachment to the DNA molecule can be detected prior to polymerization, with electrode capacitance measurement using the same voltage-clamp amplifier. This technique and device may be adapted to other reaction determinations, such as enzymatic reactions, other electrode configurations, and other amplifying circuits.

11-17-2011

20120283107

Charge Perturbation Detection Method for DNA and Other Molecules - Methods for direct detection of chemical reactions are provided. Electric charge perturbations of the local environment during enzyme-catalyzed reactions are sensed by an electrode system with an immobilized target molecule. The charge perturbation caused by the polymerase reaction can uniquely identify a DNA sequence. The polymerization process generates local perturbations of charge in the solution near the electrode surface and induces a charge in a polarazible gold electrode. This event is detected as a transient current by a voltage clamp amplifier. Detection of single nucleotides in a sequence can be determined by dispensing individual dNTPs to the electrode solution and detecting the charge perturbations. Alternatively, multiple bases can be determined at the same time using a mix of all dNTPs with subsequent analysis of the resulting signal. This technique may be adapted to other reaction determinations, such as enzymatic reactions, other electrode configurations, and other amplifying circuits.

11-08-2012

20130240379

CHARGE PERTURBATION DETECTION SYSTEM FOR DNA AND OTHER MOLECULES - Methods and apparatus for direct detection of chemical reactions are provided. Electric charge perturbations of the local environment during enzyme-catalyzed reactions are sensed by an electrode system with an immobilized target molecule. The charge perturbation caused by the polymerase reaction can uniquely identify a DNA sequence. The polymerization process generates local perturbations of charge in the solution near the electrode surface and induces a charge in a polarazible gold electrode. This event is detected as a transient current by a voltage clamp amplifier. Detection of single nucleotides in a sequence can be determined by dispensing individual dNTPs to the electrode solution and detecting the charge perturbations. Alternatively, multiple bases can be determined at the same time using a mix of all dNTPs with subsequent analysis of the resulting signal. This technique may be adapted to other reaction determinations, such as enzymatic reactions, other electrode configurations, and other amplifying circuits.

09-19-2013

20150198559

FUNCTIONALIZED NANOPIPETTE BIOSENSOR - Disclosed are methods and devices for biomolecular detection, comprising a nanopipette, exemplified as a hollow inert, non-biological structure with a conical tip opening of nanoscale dimensions, suitable for holding an electrolyte solution which may contain an analyte such as a protein biomolecule to be detected as it is passed through the tip opening. Biomolecules are detected by specific reaction with peptide ligands chemically immobilized in the vicinity of the tip. Analytes which bind to the ligands cause a detectable change in ionic current. A sensitive detection circuit, using a feedback amplifier circuit, and alternating voltages is further disclosed. Detection of IL-10 at a concentration of 4 ng/ml is also disclosed, as is detection of VEGF.

07-16-2015

20160138093

Charge Perturbation Detection System for DNA and Other Molecules - Methods and apparatus for direct detection of chemical reactions are provided. Electric charge perturbations of the local environment during enzyme-catalyzed reactions are sensed by an electrode system with an immobilized target molecule. The charge perturbation caused by the polymerase reaction can uniquely identify a DNA sequence. The polymerization process generates local perturbations of charge in the solution near the electrode surface and induces a charge in a polarazible gold electrode. This event is detected as a transient current by a voltage clamp amplifier. Detection of single nucleotides in a sequence can be determined by dispensing individual dNTPs to the electrode solution and detecting the charge perturbations. Alternatively, multiple bases can be determined at the same time using a mix of all dNTPs with subsequent analysis of the resulting signal. This technique may be adapted to other reaction determinations, such as enzymatic reactions, other electrode configurations, and other amplifying circuits.

05-19-2016

Patent applications by Miloslav Karhanek, Santa Cruz, CA US

Miloslav Krystufek, Brussels BE

Patent application number

Description

Published

20140208703

GAS/LIQUID SEPARATOR AND COMPONENTS; LIQUID DRAIN FLOW ASSEMBLIES; SYSTEMS OF USE ; AND, FEATURES; AND, COMPONENTS - According to the present disclosure gas/liquid separator assemblies, such as crankcase ventilation filter assemblies, and components are described. Also described are liquid flow control arrangements for facilitating liquid flow from a region of first effective pressure to a region of second higher effective pressure are described. In examples, the flow control arrangements are configured so they can be used in association with a gas/liquid separator, managing separation of liquids from crankcase ventilation gases, for example for internal combustion engines. Example arrangements are described, used with crankcase ventilation gas filter assemblies. Combinations of equipment, and various components usable in those combinations, are described.

Miloslav Kubar, Prague CZ

Patent application number

Description

Published

20160141052

ELECTRONIC MEMORY DEVICE AND TEST METHOD OF SUCH A DEVICE - The electronic memory device comprises a non-volatile memory matrix organized in rows and columns, an address decoder with address input lines for selecting a row according to a particular address given on the address input lines. Additional address mask input lines are provided, each address mask input line being assigned to an address input line, wherein an address mask input line in activated state has the effect of ignoring the assigned address input line. The method for testing said electronic memory device is performed with a significant lower number of read/write operations, since by ignoring a particular address line a plurality of write operations can be performed simultaneously.

05-19-2016

Miloslav Kverka, Prague CZ

Patent application number

Description

Published

20090118173

TREATMENT AND PREVENTION OF INFLAMMATORY BOWEL DISEASES - The present invention relates to the use of heat shock proteins, or fragments thereof, for the treatment and/or prevention of Inflammatory Bowel Diseases. Preferably bacterial and/or mammalian heat shock proteins belonging to the HSP70 families are used.

05-07-2009

Miloslav Milichovský, Pardubice CZ

Patent application number

Description

Published

20090306363

Preparation Method of Bioresorbable Oxidized Cellulose - Bioresorbable material made of oxidized natural or regenerated cellulose intended primarily for health care purposes is prepared in such a way that a solvent from the family of perfluoroethers or perfluoropolyethers with the boiling point between 50 and 110° C. is used for the oxidation by dinitrogen tetraoxide.

12-10-2009

Miloslav Milichovský, Pardubice CZ

Patent application number

Description

Published

20090306363

Preparation Method of Bioresorbable Oxidized Cellulose - Bioresorbable material made of oxidized natural or regenerated cellulose intended primarily for health care purposes is prepared in such a way that a solvent from the family of perfluoroethers or perfluoropolyethers with the boiling point between 50 and 110° C. is used for the oxidation by dinitrogen tetraoxide.

12-10-2009

Miloslav Trmac, Brno CZ

Patent application number

Description

Published

20140079221

MANAGING ENCRYPTED DATA AND ENCRYPTION KEYS - A data module encrypts a first portion of a drive in a data center using a first encryption key. The data module encrypts the first encryption key using a second encryption key to obtain an encrypted encryption key. The data module stores the second encryption key in a first location and stores the encrypted encryption key in a second location that is separate from the first location and that is inaccessible from outside the data center.