What we'd need is more the content portion of a homepage, which we'll insert into a skin/L'n'F you can assume already exists.
The base skin will be 960px wide, and we can easily implement columns of varying widths.
We'll be using either the Blueprint or 960 CSS framework, if you're familiar with either.
Separately, in another email, at a later date, we may request some help with the skin/L'n'F, but this is orthogonal to that. And we're not asking for that. Yet. So, think homepage-marketing-content, and we'll slap it into a hole about 900px wide.