Hydroxyzine Base
fda sheet

Hydroxyzine Base
msds (material safety sheet)

Hydroxyzine Base
Synthesis Reference

Hydroxyzine Base
Molecular Weight

Hydroxyzine Base
Melting Point

190 oC

Hydroxyzine Base
H2O Solubility

< 700 mg/mL

Hydroxyzine Base
State

Solid

Hydroxyzine Base
LogP

3.036

Hydroxyzine Base
Dosage Forms

Capsule; Liquid; Solution; Syrup

Hydroxyzine Base
Indication

For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria.

Hydroxyzine Base
Pharmacology

Hydroxyzine, a piperazine antihistamine structurally related to buclizine, cyclizine, and meclizine, is used to treat histamine-mediated pruritus or pruritus due to allergy, nausea and vomiting, and, in combination with an opiate agonist, anxiolytic pain. Hydroxyzine is also used as a perioperative sedative and anxiolytic and to manage acute alcohol withdrawal. Hydroxyzine's active metabolite, cetirizine, is also used as an H1-antagonist.