Cardiovascular diseases are the number one cause of death globally. Via this project the selected PhD student will carry out multi-disciplinary translational research using both in vitro and in vivo approaches to study the causes of atherosclerosis. Read more

Control of blood cell proliferation, survival and activation is critical to the health of an organism. Defects in this control can lead to a wide range of diseases or pathological conditions including cancer, immunodeficiencies or autoimmunity. Read more

A critical role for phagocytic cells such as macrophages is the engulfment and subsequent degradation of dying cells and debris. Failure to clear targets such as apoptotic cells can lead to damaging autoimmune conditions and immune cell dysfunction (Morioka et al., 2019; Roddie et al., 2019). Read more

Plant growth and development is highly dependent on the light environment. Light provides energy to drive photosynthesis but light quality and quantity is also perceived by photoreceptors, which signal to regulate responses enabling plants to adapt to their environment. Read more

The tetraspanins are a diverse, conserved family of eukaryotic membrane proteins. Their principal feature is the ability to form dynamic multi-molecular assemblies in cell membranes known as tetraspanin enriched microdomains (TEM). Read more

Primary cilia are ancient organelles present at the surface of many cell types in vertebrates. In recent years, they have been shown to play essential roles in relaying sensory and signalling information from the environment to the cell. Read more