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O’Neill was born in Montreal. Although her father is from Montreal, her mother is of Southern American descent. O’Neill spent the first part of her childhood in Montreal. After her parents’ divorce, she lived in the American South with her mother for several years before returning to Montreal to live with her father. She has lived in Montreal ever since. She was educated at Dawson College and McGill University. She has one daughter named Arizona.[3]

O'Neill has written a book of poetry entitled two eyes are you sleeping.

Her 2008 short story "The End of Pinky" was adapted as a 2013 animated short of the same name, with O'Neill providing English narration.[8] In December 2013, it was named to the Toronto International Film Festival's annual top ten list, in the short film category.[9]