Researchers suggest that using mouthwash at least twice every day destroys "friendly" oral bacteria, which can, in turn, alter blood sugar metabolism and promote diabetes, particularly for people who are already at high risk for the condition.

"Patterns of persistence, intolerance, and inadequate response with methotrexate [MTX] are not well characterized in real-world settings. We all get the sense that there are patients who greatly dislike it.”