autoimmune

A few weeks ago I blogged about a new pilot study about the use of a skin moisturizer twice a day reduced inflammation in older adults. I use the inflammation research to question if this may be applicable and helpful for you if you suffer from anxiety, extrapolating that it may well be given the added benefits of touch and an oxytocin boost.

I received a number of great questions about how to apply this information and have decided to share a question from someone with both Sjogren’s syndrome and anxiety, in order to illustrate how I’d work with someone like this.

Here is the question I received:

I would like to know how much of one’s body needs to be moisturized, and if it is also necessary to be done twice per day? Such a simple but effective way to help with anxiety. Will be slathering a lot more in the future! I have Sjogren’s so everything is dry – skin, mouth, eyes, hair. I have been trying to keep my face much “moister” and I am sure my wrinkles have lessened. I find rice bran oil is also quite good.

I’m going to address her moisturizing question below and share more about anxiety in Sjogren’s syndrome and some nutritional solutions, but first let me explain what Sjogren’s syndrome is.

An overview of Sjogren’s syndrome

Let me explain what Sjogren’s (SHOW-grins) is in case you’re not familiar with this condition. It’s an autoimmune condition and is described as follows on the Mayo Clinic site:

often accompanies other immune system disorders, such as rheumatoid arthritis and lupus. In Sjogren’s syndrome, the mucous membranes and moisture-secreting glands of your eyes and mouth are usually affected first — resulting in decreased tears and saliva.

Although you can develop Sjogren’s syndrome at any age, most people are older than 40 at the time of diagnosis. The condition is much more common in women.

The site goes on to say that other than dry eyes and mouth, some people experience joint pain and stiffness, swollen salivary glands, skin rashes or dry skin, vaginal dryness, persistent dry cough and prolonged fatigue. It’s worth a read to learn more about complications like more dental cavities, yeast infections, vision issues, problems in the lungs, kidneys or liver, the risk of lymphoma and peripheral neuropathy.

My feedback about moisturizing

In the study, moisturizing was done twice a day. I’m not sure how much of the body needs to be moisturized but if everything is dry, I’d want to moisturize as much as possible.

Given that chronic inflammation is a major factor in Sjogren’s and other autoimmune conditions like systemic lupus erythematosus, it’s feasible to expect similar benefits in terms of reduced inflammation. Hopefully we’ll see research on autoimmune conditions in the future.

When it comes to anxiety, I do want to make it clear that I was and still am extrapolating from the research on inflammation and measuring reduced anxiety was not part of the study. Moisturizing may or may not help with anxiety and I certainly wouldn’t only use this intervention.

Anxiety in Sjogren’s – low serotonin and GABA?

You may not be aware that anxiety/depression is very common in Sjogren’s. In one study they

found 33.8% patients with anxiety, and 36.9% had depression, which were significantly higher than controls.

I use a comprehensive nutritional and lifestyle approach to help my clients ease their anxiety and as I mention above, I would not only rely on moisturizing.

They didn’t find a correlation between the levels of serotonin and how severe the Sjogren’s symptoms were, which falls in line with what we know about biochemical individuality and why doing a trial of tryptophan or 5-HTP (to find your ideal dose) is the best approach for serotonin support.

If you recall, in the Mayo Clinic description above, stiffness is a common symptom of Sjogren’s and GABA eases stiffness.

I haven’t found any research on GABA in Sjogren’s, but one case study reports that a patient experiencing athetoid movements (a movement dysfunction, characterized by involuntary writhing movements), reported symptom improvement with hydroxychloroquine, pilocarpine, gabapentin, and clonazepam. The latter two medications work on the GABA system.

If you recall, in the Mayo Clinic description above, joint pain and dental cavities are common symptoms. These are also very common with pyroluria, so using a nutritional approach helps ease the social anxiety, and improves joint issues and mouth health.

Sjogren’s and the Autoimmune-Paleo diet

Since Sjogren’s is an autoimmune condition, following an Autoimmune-Paleo (AIP) diet is key too. Here are some books that are well-worth making part of your library, even though they are not specific to Sjogren’s syndrome they offer support for autoimmune conditions (and many individuals often have more than one autoimmune disease)

Here is one more resource for you: The Autoimmune Masterclass which airs online this weekend It’s a similar format to online 7-day summits but runs for 2 days instead and is no-cost to attend during these two days.

I haven’t dived into the research on all the other autoimmune conditions and the above connections (low serotonin, low GABA and pyroluria) but it’s highly likely similar connections exist. So, if you have any autoimmune condition and anxiety this could all apply for you too.

If you have been diagnosed with Sjogren’s syndrome please share if GABA and tryptophan have helped ease your anxiety, and if the pyroluria protocol has helped you with social anxiety?

And let us know if moisturizing is helping your dry skin and possibly reducing inflammation and anxiety too?

There is a wonderful new recipe book out this week and I want you to know about it!

Dealing with an autoimmune or other chronic health condition such as Hashimoto’s, IBS, Celiac, RA, Psoriasis, chronic fatigue or fibromyalgia, or even just committing to your family’s health does NOT have to mean giving up delicious foods!

Amy Myers reversed her own autoimmune condition by addressing the root causes of her illness and diet played a HUGE role. She continues to follow the same dietary program that she recommends to her patients and community.

We actually ate out together in Melbourne at the recent Bioceuticals Symposium and I saw her put The Myers Way® (her proven program) of eating into practice at the restaurant, making sure everything she was eating was safe and would not trigger an autoimmune flare. Our server worked hard making sure all her questions were addressed in a satisfactory manner and she set a great example for all of us.

She does this in her wonderful new cookbook, setting a great example and guiding you to make the right choices in order to reduce inflammation, heal your leaky gut and help you move toward the optimal health side of the autoimmune spectrum and stay there.

When I was growing up in New Orleans, my grandparents took the family out to dinner at the Yacht Club for special occasions, and I always ordered a fried shrimp po’ boy—a traditional Louisiana sandwich. This substitute for fried shrimp is a healthier option that everyone will love. The shrimp are tossed with coconut flour and shredded coconut instead of breadcrumbs— and they are so easy to make! My husband and I served this as an appetizer at our wedding and they were a huge hit! Serves 4

In another shallow bowl, whisk together the coconut milk and coconut aminos.

Dip each shrimp into the liquid mixture, and then into the dry mixture to coat. Arrange in a single layer in a baking dish. Bake for 15 to 20 minutes, until golden brown. For extra crispiness, remove the pan and set the oven to broil. Broil the shrimp for 4 to 5 minutes.

Some of the other recipes I’m really looking forward to trying are the creamy zucchini-basil soup, the herbed roast chicken, the world’s best Asian flank steak, the rosemary sea-salt crackers (made with cassava flour), the spinach artichoke dip (I’ll replace the spinach with low-oxalate dino kale), raspberry cheesecake bites (I’ll make it with blueberries instead of high-oxalate raspberries), and the apple crisp. There are so many delicious recipes!

There is no perfect eating plan for everyone and Amy has created this eating plan and recipes to cater for the majority of those with an autoimmune condition. I really appreciate that recipes are marked as being autoimmune-friendly, thyroid-friendly, suitable for candida and SIBO, and low histamine. However, if you do have oxalate issues you will need to adjust some of the recipes. Also, if you have issues with collagen making your anxiety or insomnia worse then I recommend adding some protein powder to the recipes that call for gelatin or collagen, and/or consider a trial of tryptophan.

Here’s the official book blurb:

The companion cookbook to the revolutionary New York Times bestseller The Autoimmune Solution, filled with more than 150 nutritious, easy-to-prepare, every day recipes to heal symptoms of inflammation and autoimmune disorders, including Graves’ Disease, Psoriasis, Fibromyalgia, Lupus, Celiac disease, Hashimoto’s thyroiditis, and Multiple sclerosis.

Nine in ten Americans suffer from inflammation or an autoimmune disorder—conditions for which conventional medicine has no cure. Minor irritations like rashes and runny noses are ignored, while chronic and debilitating diseases like Crohn’s and rheumatoid arthritis are handled with a cocktail of toxic treatments that fail to address their root cause. But as Dr. Amy Myers revealed in The Autoimmune Solution, there are solutions. In this invaluable cookbook, she now shows you how to repair your body and reverse your symptoms by eating your way to good health.

The Autoimmune Solution Cookbook delivers more than 150 grain-free recipes designed to prevent and reverse the full spectrum of autoimmune diseases, including allergies, obesity, asthma, cardiovascular disease, fibromyalgia, lupus, IBS, chronic headaches, fatigue, multiple sclerosis, colitis, Graves’ disease, and Hashimoto’s thyroiditis. As our food and environment becomes more toxic, the health of millions of us have been impaired. Thanks to Dr. Myers, you no longer need to rely on prescriptions—with troubling, sometimes dangerous side effects—to counteract your body’s over-reactive immune system. The Autoimmune Solution Cookbook is the healthy alternative to cope with and conquer inflammatory-related symptoms and diseases.

If you’re ready to enjoy amazing meals that will help you take back your health and your life, this book is an absolute must-have, so get your copy of The Autoimmune Solution Cookbook today – on Amazon here (my affiliate link) or from your favorite book store.

This cookbook is the perfect companion to The Autoimmune Solution(my affiliate link), a wonderful book that introduced The Myers Way®, empowering so many to reverse their autoimmune conditions.

And stay tuned for an email notification from Dr. Myers about the upcoming Autoimmune Program webinar being held online on May 17. She’ll be sharing more about her group program if you’re the kind of person looking for a community-based program.

Happy cooking and do let us know how you enjoy the recipes!

If you have questions or feedback please post them in the comments below.

I highly recommend Dr. Darin Ingels, ND new book The Lyme Solution: A 5-Part Plan to Fight the Inflammatory Auto-Immune Response and Beat Lyme Disease. As a functional medicine practitioner, he provides a natural approach to treating Lyme disease that is both comprehensive and designed to each person’s own unique needs i.e. he doesn’t use a one size fits all approach. His uniquely holistic approach to treating this rampant disease, treats both the infection and the resulting autoimmune response. He’s also recovered from Lyme disease himself so he really gets it!

According to the CDC, over 300,000 cases of Lyme are reported every year in the U.S.A.

As you can see, many conditions can mimic Lyme disease, including anxiety and depression.

Many in my community have both Lyme disease and anxiety and many nutritional solutions, such as GABA (a calming amino acid supplement), can ease their anxiety while my client is working with a doctor such as Dr. Ingels in order to address and eliminate the Lyme disease.

Dr. Ingels shared this with me when I asked about what GABA products he likes and why:

I use DFH PharmaGaba and Allergy Research Liposomal GABA, which also has theanine. Liposomal GABA works beautifully for anxiety and sleep disturbances in my Lyme patients and children with autism. I also love how quickly it seems to affect people, often within 10-15 minutes of taking it.

Including the latest research about the diagnosis and treatment of Lyme, The Lyme Solution provides a path to wellness by strengthening the body’s ability to heal from within. Dr. Ingels suggests an actionable 5-Part Plan to:

Fortify gut health and restore the immune system

Follow a diet that increases immunity and reduces inflammation

Thwart and target an active infection

Identify hidden toxins that worsen Lyme

Lifestyle suggestions to help healing

Here are some of his gut support protocols: digestive enzymes, glutamine, resveratrol, herbs like slippery elm and marshmallow, fish oil and probiotics:

The Lyme Solution is a simple guide for how you can advocate for your own health and use innovative treatments to maintain wellness, using the least invasive ways to facilitate treatment. By following this plan, you can become even stronger than you were before the Lyme and better equipped to manage recurring symptoms.

UPDATE: April 20, 2018 – My actual review

I highly recommend this book if you have Lyme disease or if you suspect that Lyme disease may be playing a role in your ill-health or have chronic anxiety (or another chronic health condition) and have not yet found a solution. I also highly recommend it for practitioners who are both treating Lyme disease patients and those, like myself, who want to really understand all aspects in order to make good referrals for Lyme treatment.

I read it cover to cover in one sitting and could not put it down!

Chapter 1 – An excellent discussion about the problems with long-term antibiotics for chronic Lyme disease and when antibiotics should be used. The chronic inflammatory autoimmune connection is unique to Dr. Ingels’ approach for treating Lyme disease and makes a great deal of sense. The Lyme facts are invaluable: Lyme spirochete going dormant and hiding in scar tissue and lymph nodes; the nymph the most dangerous; Lyme-reactive antibodies form against proteins in the brain, giving rise to neurological symptoms.

Chapter 2 – Covers complex and controversial issues with diagnosis and pitfalls of the various testing that is available. It contains Lyme signs/symptoms and a Lyme questionnaire. It was eye-opening to learn that the bull’s-eye rash is Lyme specific and that changes in handwriting and mixing up words may be a sign of chronic Lyme disease. This is one of my favorite chapters of the book and is very comprehensive.

Chapter 3 – Gut and immune restoring protocols and more on the autoimmune connection. Addressing gut health is key to any condition and Dr. Ingels reiterates that addressing the immune system is key for recovery from Lyme.

Chapter 4 – Immune boosting diet and the importance of alkalinity. This is my least favorite chapter because I’m an advocate of the Paleo diet and have found that when done well with large amounts of vegetables, it is healing and alkaline. (He did connect with me on this and agrees in principle with a Paleo diet that does include plenty of vegetables). I am pleased to see coffee is off the list but would have liked to hear his experiences with intermittent fasting.

Chapter 5 – Covers targeting the infection in a way that doesn’t impact gut flora and undermine the immune system. This chapter has extensive coverage of the herbal protocols Dr. Ingels has found to be effective for his patients: Zhang protocol, his version of the Cowden protocol and others. He goes into great detail for each herb, including products to help with a Herxheimer reaction, as well as the rationale and protocols for breaking up biofilm. It’s also one of my favorite chapters in the book.

Chapter 6 – Cleaning your home and environment and getting rid of toxic chemicals and products, as well as addressing mold. This is also common-sense to address for any condition so it’s great to cover for Lyme.

Chapter 7 – Sleep, exercise and stress reduction. This is also common-sense to address for any condition. I do have a professional difference of opinion for the GABA recommendation for sleep and typically start my clients on much lower doses. I also love GABA for stress and anxiety.

Chapter 8 – Advanced protocols for specific symptoms: mitochondrial issues, neuropathy and balance, low dose immunotherapy, LDN and other approaches where you’ll need to work with a health care provider. Another favorite chapter of mine.

The case studies throughout the book reflect the complex nature of Lyme disease and help us get a better understanding about unexpected symptoms, as well as Dr. Ingels’ level of expertise. One such example is Peter’s story: he developed tics but none of the other classic Lyme symptoms, PANS was found and then Lyme disease.

Given that neuropsychiatric symptoms are common in Lyme disease I hope to see more coverage of this in a later edition or follow-up book. I work with individuals with anxiety and underlying Lyme disease is very common, with benzodiazepines and SSRIs commonly prescribed. Using nutritional approaches for the anxiety and/or depression and since it gets to the root cause it’s more effective, plus it lowers the toxic burden and side-effects of added medications. (He also connected with me about this and said he agrees but word-count was the challenge in this first book).

Overall, this book is an excellent resource and I highly recommend it! It offers practical solutions and hope for those who are been suffering with chronic Lyme disease and are seeking a solution.

Summit host, James Maskell of Evolution of Medicine, has gathered world-renowned leaders from genetics, genomics and functional medicine. These pioneering experts are on the front lines interpreting data to create improved health in patients around the globe. Learn how to translate your health data to better understand:

It means that you’re vulnerable to a particular disease. “Mrs. Patient, if you pull at a chain, it always breaks at the weakest link. Always. It’s going to be at one end, the middle, the other end. It’s your heart, your brain, your liver, your kidneys. Wherever your genetic weak link is. And where’s your weak link? Whatever your genes are. Whatever the deck of cards you’ve been dealt in life, that’s the weak link in your chain.”

So when you have that basic understanding, the first thing that comes up is stop pulling on the chain so much, right. And then, the link won’t break. And how do you stop pulling on the chain? Reduce the inflammation, reduce the activation of your immune system, which is what turns on the genes.

James summarizes this concept perfectly:

So what I hear you saying is that whatever your genetic test comes back, you want to be minimizing the pull on the chain. And you want to be minimizing and repairing the holes in your gut to make sure that you don’t end up with a broken-chain situation, which would be an autoimmune disease, which could manifest anywhere depending on your genetic makeup.

Tom O’Bryan discusses some common environmental triggers that will “pull on the chain” in great detail, and how they lead to genes being turned on and hence causing disease: food quality, wheat, dairy sugar, glyphosate, plastic and air quality. He also covers the APOE4 genes that increase your risk for Alzheimer’s disease and shares this scary fact about kids in Mexico City:

what they have found is that every child that they checked in Mexico City has evidence of early Alzheimer’s. Every child! Let me say that again. Every child that they check has evidence of early Alzheimer’s.

Why? Because the air pollution is so bad. And you breathe that stuff in. It goes into your lungs. And just like leaky gut, you get leaky lungs. And this particulate matter goes right through the lungs, into the bloodstream, straight up to the brain, activating your immune system to fight this stuff. Tears the lining of the blood-brain barrier.

And he shares one of his favorite tests for determining if damage is being done to the brain:

8-hydroxy-2′- Deoxyguanosine… a measure of the DNA residue from damaged brain cells or damaged nerve cells, mostly in the brain. So you just do a simple urine test. And if your 8-hydroxy is up, you’re killing off brain cells. And that makes you say, “Well, why?” [this is the DNA Oxidative Damage Assay from Doctor’s Data]

And this one to look at antibodies to the blood-brain barrier:

You have a simple type of lining on your brain that stops molecules from getting in the brain that shouldn’t be here. So you want to look for antibodies… to S100B. There’s a panel of antibodies that you could look for to see, “Is my brain on fire right now,” because if you have elevated antibodies, your brain is on fire. You’re killing off brain cells.

This interview sets the stage for the rest of the summit! I can’t wait to learn from these amazing speakers on this very relevant and cutting-edge topic.

Once you register you’ll have access to this interview and 2 others (Epigenetic Mastery for Everyone from Andrea Nakayama, CNC, CNE and The Current State of Genetics from Jeffrey Bland, PhD) right away.