Post Accutane Syndrome (PAS)Forum software by XenForoThu, 24 May 2018 17:44:14 +0000Thu, 24 May 2018 17:44:14 +0000Post Accutane Syndrome (PAS)https://www.pasforum.info/
THEORY - PAS and PSSD/Serotonin Theory - (Serotonin Overactivity - 5HT2C Receptors) - Plausible/Would be TreatableWed, 23 May 2018 22:14:21 +0000https://www.pasforum.info/threads/theory-pas-and-pssd-serotonin-theory-serotonin-overactivity-5ht2c-receptors-plausible-would-be-treatable.2/
https://www.pasforum.info/threads/theory-pas-and-pssd-serotonin-theory-serotonin-overactivity-5ht2c-receptors-plausible-would-be-treatable.2/invalid@example.com (flynn)flynnPAS and PSSD have remarkable similarities, both involve persisting sexual dysfunction along with other mental side effects such as depersonalisation, anhedonia, depression and apathy/emotional numbness. Both conditions appear to be fairly unresponsive to hormone therapy and dopamine agonists. This is unusual as both androgen therapy and dopamine agonists act directly on the dopaminergic system of the brain, which is thought to play a major role in sexual function, reward and pleasure. One...

Post:
Loss of Libido.
Loss of Morning Erections/Spontaneous Erections/Nocturnal Erections.
Watery Ejaculate
When i reach orgasm, i feel nothing in my brain, i used to feel pleasure and...

Cyclope - Blood Results]]>2Prof Melcangi - PFS and PSSDWed, 23 May 2018 21:58:43 +0000https://www.pasforum.info/threads/prof-melcangi-pfs-and-pssd.44/
https://www.pasforum.info/threads/prof-melcangi-pfs-and-pssd.44/invalid@example.com (flynn)flynnProf Melcangi who is the a major researcher for the PFS foundation recently released a paper linking PFS to PSSD. I think he is probably correct, but it seems crazy that nobody is even mentioning PAS or post retinoid sexual dysfunction (PRSD) as there are far clearer links been PFS and PAS then PSSD

http://www.pfsfoundation.org/tag/roberto-melcangi/]]>0THEORY - PAS and PFS - 5-Alpha Reductase Enzyme - Very Plausible/Currently seems to be the most likely cause of PASWed, 23 May 2018 20:58:56 +0000https://www.pasforum.info/threads/theory-pas-and-pfs-5-alpha-reductase-enzyme-very-plausible-currently-seems-to-be-the-most-likely-cause-of-pas.9/
https://www.pasforum.info/threads/theory-pas-and-pfs-5-alpha-reductase-enzyme-very-plausible-currently-seems-to-be-the-most-likely-cause-of-pas.9/invalid@example.com (flynn)flynnThe following posts are fairly long, but if you are interested in how PAS arises, then I think they are worth reading. Of all the theories, this one seems to be the most plausible/likely in my opinion.

Another theory of PAS relates to Post Finasteride Syndrome (PFS), this is a recognised syndrome which a subset of men develop after taking the hair loss drug Finasteride (FIN) also known as Propecia. Unfortunately the underlying cause of PFS is still a mystery. However there is strong reason...

I feel as if tane has made me more prone to anxiety. I see numerous people complain of feeling more anxious and susceptible to anxiety. Again this is a common symptoms in people with PFS.

This is a stretch but if PAS is linked to 5 alpha reductase. It would make sense that people with PAS may have greater anxiety. As the activity of 5 alpha reduced metabolites in the amygdala play a role in reducing anxiety -...

Anxiety]]>4Hyperbaric Oxygen Therapy...and Wutou Decoction?Sun, 20 May 2018 10:39:26 +0000https://www.pasforum.info/threads/hyperbaric-oxygen-therapy-and-wutou-decoction.43/
https://www.pasforum.info/threads/hyperbaric-oxygen-therapy-and-wutou-decoction.43/invalid@example.com (johnniehaz)johnniehazHas anybody had any thoughts on either of these? I'm sure you've heard about HBOT being used for traumatic brain injury. Some rate its efficacy more than others.
The Wutou Decoction is reported to modulate epigenetic expression, and to have significant impact on rheumatoid arthritis. If the theory is that the Accutane caused epigenetic markers to be put down, might things like this be of interest...

https://rxisk.org/enduring-sexual-dysfunction-300-cases/]]>0GHB - GammahydroxybutrateThu, 10 May 2018 19:47:51 +0000https://www.pasforum.info/threads/ghb-gammahydroxybutrate.30/
https://www.pasforum.info/threads/ghb-gammahydroxybutrate.30/invalid@example.com (flynn)flynnI've posted about this on the other thread. But just thought I'd write about this here.

It reported to work very well for anxiety and supposedly helps a lot with increasing general interest in the opposite sex. People have said that this has helped them more than anything else in that department. It's also been reported that its effect on anxiety and ability to induce euphoria also really helps improve mood and enhance personality.

It has a terrible reputation as a "date rape drug", but...

GHB - Gammahydroxybutrate]]>7Legal options?Wed, 09 May 2018 11:00:09 +0000https://www.pasforum.info/threads/legal-options.39/
https://www.pasforum.info/threads/legal-options.39/invalid@example.com (30goingon60)30goingon60I'm a 33 year old male who took accutane at 14 17 and 20 for mild/moderate acne. There is no question this is one of the most dangerous drugs ever created, and I blame it for taking my one life away from me. I've been on the forums over the years sympathizing with the others who are suffering as well, but have never seen any mention of legal action. With over 12 million people having taken this drug worldwide, isn't there anyway we could organize some kid of class action law suit against...