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Tamara Alliston, PhD

One in three American adults suffer from arthritis symptoms, yet the molecular basis of this degenerative skeletal disease remains unclear. Our research focuses on the molecular pathways controlling mesenchymal stem cell differentiation, how these pathways function in normal skeletal tissue, and how they can be harnessed to repair tissue damaged in degenerative skeletal disease. To answer these questions we combine molecular, cellular, physiologic, and materials science approaches. I believe this interdisciplinary approach will lead to the identification of targets to prevent skeletal disease or to improve skeletal repair.