DescriptionIn the past few years, we have driving a deliberate intersection of next generation high-performance computing technologies with AI and Big Data to create new types of opportunities that could help shape precision medicine in the future. We are have been piecing together a most unique intersection of medical data and computer technologies. It includes partnerships with other federal agencies, private sector and academia, and foreign governments. In this talk, I will outline why, what and how we are doing this and where we are headed and the types of data we are bringing together in this enterprise. I believe that future economies built from thinking along these lines will provide a means to advance precision medicine, drive next generation technologies and foster innovation.