Fresh from defeating San Francisco’s Proposition F, which sought to curtail vacation rentals, Airbnb plans to organize its hosts and guests worldwide into city-based guilds to lobby for turning homes into hotels. It aims to have 100 such clubs up and running by the end of 2016.

“We’re going to build on the momentum coming from San Francisco ... to give our community access to the finest grassroots training, tools and support,” said Chris Lehane, Airbnb head of global policy, at a press conference at the company’s South of Market headquarters. While he said the plan is for “independent clubs to be run by hosts and guests,” the $25.5 billion company will provide such help as dedicated Airbnb staff, information, support and a hotline to its headquarters, he said.

Airbnb’s explosive growth — it has more than 2 million listings in 34,000 cities — has spurred pushback from lawmakers, neighbors, landlords and housing activists in many of those cities. While San Francisco opponents were the first to mount a ballot measure that would have drastically hobbled it, cities from New York to Barcelona are contemplating strict regulations.

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“Other cities around the state and country who are struggling with the same issues have been in touch with us,” said Dale Carlson, who spearheaded the Prop. F campaign. “Next year, Airbnb may have to spend $100 million to fight ballot measures all over the place.”

The company acknowledges that its battles are far from over.

“Airbnb knows there will always be a public policy threat out there that could shake up their business in a fundamental way, so it makes sense that they’d take the next step to try to build their network,” said Edward Walker, a UCLA sociology professor and author of “Grassroots for Hire” about corporate-backed political movements. The guild idea “shows the next step in the merging of marketing and political strategies,” Walker said.

Airbnb’s hosts have genuine self-interest in supporting it, so the effort can’t be termed an “Astroturf,” or fake grassroots, lobby — and Airbnb has been transparent about its role in helping to organize them, Walker said.

In San Francisco, some 138,000 people are guests or hosts — more than the 132,262 who voted in Tuesday’s election, and also more than other blocs, such as 42,000 registered Republicans, he said.

Local hosts formed a group called the Home Sharers Democratic, which directly reached out to voters and the media to campaign against Prop. F, Lehane said. That helped spur the guild idea.

Lehane declined to say how much Airbnb might spend on the clubs. It put $8.5 million into the campaign to defeat Prop. F, dramatically outspending the other side. Still, the provisional results — 55 percent of voters (73,556 people) rejected the measure, while 45 percent (60,025) supported it — were closer than many observers had expected, and closer than polls commissioned by Airbnb had projected. (Late mail-in ballots are still being counted.)

Nevertheless, Lehane portrayed it as an unalloyed victory.

“What took place here in San Francisco has informed us enormously,” he said. “It’s a great lesson and a template for how we’re going to go forward.”