LA JOLLA  Scripps Health moved another notch forward in its $2 billion renovation plan for Scripps Memorial Hospital La Jolla Wednesday with the ground breaking of a six-story $130 million medical office building on the Genesee Avenue medical campus.

When complete in 2016, the 175,000-square-foot building will house medical specialists from cardiologists and gastroenterologists to neurologists and endocrinologists. It will also include four cardiac catheterization labs used to perform various outpatient angioplasty procedures.

Built with a $25 million gift from the family of longtime Scripps benefactors Eileen and John “Jack” Anderson IV, the building will be called the John R. Anderson Medical Pavilion.

It will be adjacent to another big name on the La Jolla medical campus, the seven-story Prebys Cardiovascular Institute, a 108-bed facility that will consolidate the health system’s heart operations into one building when it opens in 2015.

Driven by a state mandate to retrofit or replace medical buildings that do not comply with stringent seismic safety regulations, the master plan for Scripps La Jolla has an ambitious scope. Plans call for a second hospital tower to open in 2020 and a third in 2025.

Scripps is not the only local health care player participating in the local health care building boom. La Jolla neighbor UC San Diego Health System opened its Sulpizio Cardiovascular Center in 2011 and broke ground in 2012 on Jacobs Medical Center, a 509,500-square-foot 10-story hospital building due to open in 2016. Kaiser Permanente San Diego made a move of its own in February, breaking ground on a new 565,000-square foot central hospital on Ruffin Road in Kearny Mesa at a cost of $900 million.

Correction: A previous version of this story stated that the cost of the building was $175 million. Despite including the amount in a statement Wednesday, Scripps said Thursday that the amount is $130 million.