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fda sheet

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msds (material safety sheet)

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Synthesis Reference

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Molecular Weight

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Melting Point

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H2O Solubility

100 mg/L

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State

Solid

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LogP

2.229

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Dosage Forms

No information avaliable

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Indication

For treatment of external genital warts (Condyloma acuminatum).

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Pharmacology

Podofilox, also called podophyllotoxin, is a purer and more stable form of podophyllin in which only the biologically active portion of the compound is present. Podofilox is used to remove certain types of warts on the outside skin of the genital areas.

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Absorption

Topical application of 0.05 mL of 0.5% podofilox solution to external genitalia did not result in detectable serum levels. Applications of 0.1 to 1.5 mL resulted in peak serum levels of 1 to 17 ng/mL one to two hours after application.