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Although the presence of nanobubbles in liquids has been debated for some time, Atomic Force Microscopy (AFM) studies and experimental maturity have confirmed their existence and stable population.

Nanobubbles unique characteristics for enhancing chemical conversions and increasing overall bioactivity has attracted considerable attention in diverse fields such as protein folding, stability of colloids and emulsions, biomedical engineering, pharmaceutical manufacturing, and medical therapy to name but a few. Markets such as the beverage and livestock industry have already experienced extraordinary benefits in using water saturated with nanobubbles.