ABSTRACT: USES AND MISUSES OF TROPONIN DETERMINATION IN MYOCARDIAL INFARCTION.
Currently, troponins (Tn) are the most sensitive and specific markers of myocardial damage, representing the «Gold Standard» of the diagnosis and prognosis of acute coronary syndromes (SCA). The immunological assay of cardiac troponin has evolved considerably. The current generations of available tests have an analytical sensitivity nearly one hundred times higher than at the time of their discovery. However, there is no standardization between the different dosing kits. The development of new technologies allows the dosing of minute amounts of troponins called «ultra-sensitive (Tn Us) or hypersensitive (Tn Hs) troponins» which makes identifying patients with SCA easier. However, its use in clinical practice has yet to be optimized in terms of the importance of timing, the interpretation of observed changes, the use of algorithms adapted to the population tested, or even the establishment of specific reference values For sex and age.Key words: Ultra-sensitive Troponins, Acute Coronary Syndrome.