DR ANTHONY MELVIN CRASTO,WorldDrugTracker, helping millions, A 90 % paralysed man in action for you, I am suffering from transverse mylitis and bound to a wheel chair,With death on the horizon, This will not stop me, Gods call only..........DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 29Yrs Exp. in the feld of Organic Chemistry,Working for GLENMARK PHARMA at Navi Mumbai, INDIA. Serving chemists around the world. Helping them with websites on Chemistry.Million hits on google, world acclamation from industry, academia, drug authorities for websites, blogs and educational contribution

University College Cork

Biography

Professor Anita Maguire commenced as Vice President for Research and Innovation in UCC in January 2011.

Anita undertook undergraduate and postgraduate studies in Chemistry at UCC (B.Sc. 1985, Ph.D. 1989). Following postdoctoral research first at Namur, Belgium then at the University of Exeter, UK she returned to the Department of Chemistry in UCC in 1991, initially as a College Lecturer, then Associate Professor in Organic Chemistry in 2002, and was appointed to the newly-established Chair of Pharmaceutical Chemistry in 2004, playing a leading role in development of the School of Pharmacy in recent years. Since her appointment at UCC she has played a strategic role in the development of teaching and learning, including the introduction of Medicinal and Pharmaceutical Chemistry at undergraduate level for the first time.

Over the past twenty years at UCC she has led an active research team focusing on synthetic organic and pharmaceutical chemistry, which interacts extensively with the pharmaceutical sector in Ireland and internationally. She is very committed to postgraduate education, ensuring the research students gain the skills required to underpin their future careers; 25 PhD and 5 MSc students have graduated from her research team since 1997, most of whom have developed careers within the pharmaceutical industry both in Ireland and internationally.

She is Director of the interdisciplinary research centre, the Analytical and Biological Chemistry Research Facility established under PRTLI3, and has served as Head of the Department of Chemistry (2005-7) and Head of the School of Pharmacy (since 2009). She was elected to the Governing Body of University College Cork in December 2003.

She is actively engaged nationally in strategic policy development in relation to research, STI policy, the academic industry interface and strategic development of the pharmaceutical industry, including as a member of the Advisory Science Council and Irish Research Council for Science, Engineering and Technology (IRCSET). For example, she chaired the Advisory Science Council Task Force on The Role of PhDs in the Smart Economy which reported in December 2009.

Member of Management Committee (2002 to date) D28 “Natural Products as a Source for Discovery , Synthesis and Application of New Pharmaceuticals”.

·Member of the ForfasTechnology Foresight Chemical and Pharmaceutical Panel (1998)

.Research:

Anita Maguire’s research interests in Synthetic Organic Chemistry and Pharmaceutical Chemistry include:Asymmetric synthesis - including biocatalysis and transition metal catalysis;Novel synthetic methodology - incl. the use of diazocarbonyl compounds & organosulfur compounds in synthesis;Design and synthesis of bioactive compounds with pharmaceutical applications;Crystal engineering;Extensive interaction with the pharmaceutical industry both within Ireland and overseas is a key feature of the research team

Affiliations:Elected as a Member of the Royal Irish Academy in 2014Fellow of the Royal Society of ChemistryFellow of the Institute of Chemistry of IrelandCChemCSci

Links:Office of VP for Research and InnovationABCRF and SSPCDepartment of ChemistrySchool of PharmacyOrganic and Pharmaceutical Synthesis Research Team

'Synthesis and assessment of the relative toxicity of the oxidised derivatives of campesterol and dihydrobrassicasterol in U937 and HepG2 cells'
O'Callaghan Y, Kenny O, O'Connell NM, Maguire AR, McCarthy FO, O'Brien NM (2013) 'Synthesis and assessment of the relative toxicity of the oxidised derivatives of campesterol and dihydrobrassicasterol in U937 and HepG2 cells'.Biochimie, 95 (3):496-503 [DOI][Details]

'Influence of the position of the substituent on the efficiency of lipase-mediated resolutions of 3-aryl alkanoic acids'
Deasy, RE,Moody, TS,Maguire, AR (2013) 'Influence of the position of the substituent on the efficiency of lipase-mediated resolutions of 3-aryl alkanoic acids'. Tetrahedron-Asymmetry, 24 :1480-1487 [DOI][Details]

'Modifications to the Vilsmeier-Haack formylation of 1,4-dimethylcarbazole and its application to the synthesis of ellipticines'
Deane, FM; Miller, CM; Maguire, AR; McCarthy, FO; (2011) 'Modifications to the Vilsmeier-Haack formylation of 1,4-dimethylcarbazole and its application to the synthesis of ellipticines'. Journal of Heterocyclic Chemistry, 48 (4):814-823 [DOI][Details]

'Stereoselective Synthesis of 2-Thio-3-Chloroacrylamides and Investigation of their Reactivity'
Kissane, Marie and Maguire, Anita R. (2011) 'Stereoselective Synthesis of 2-Thio-3-Chloroacrylamides and Investigation of their Reactivity'. Synlett, (9):1212-1232 [Details]

'The Use of Co-crystals for the Determination of Absolute Stereochemistry: An Alternative to Salt Formation'
Eccles, KS,Deasy, RE,Fabian, L,Maguire, AR,Lawrence, SE; (2011) 'The Use of Co-crystals for the Determination of Absolute Stereochemistry: An Alternative to Salt Formation'. The Journal of Organic Chemistry, 76 :1159-1162[DOI][Details]

'Enhancement of Enantioselection in the Copper-Catalysed Intramolecular Buchner Reaction by Variation of the Counterion'
O'Neill, S,O'Keeffe, S,Harrington, F,Maguire, AR; (2009) 'Enhancement of Enantioselection in the Copper-Catalysed Intramolecular Buchner Reaction by Variation of the Counterion'. Synlett, :2312-2314 [DOI][Details]

There is a growing trend in Ireland toward greater collaboration between academia and the pharmaceutical industry. This is an activity encouraged at a national policy level as a means of providing researchers from academic institutions the opportunity to gain important first-hand experience in a commercial research environment, while also providing industry access to expertise and resources to develop new and improved processes for timely medicines. The participating company benefits in terms of its growth, the evolution of its strategic research and development, and the creation of new knowledge that it can use to generate commercial advantage. The research institute benefits in terms of developing skill sets, intellectual property, and publications, in addition to access to identified current industry challenges. A case study is provided describing the collaborative partnership between a synthetic chemistry research team at University College Cork (UCC) and Eli Lilly and Company.

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DR ANTHONY MELVIN CRASTO, Born in Mumbai in 1964 and graduated from Mumbai University, Completed his Ph.D from ICT, 1991,Matunga, Mumbai, India, in Organic Chemistry, The thesis topic was Synthesis of Novel Pyrethroid Analogues, Currently he is working with GLENMARK PHARMACEUTICALS LTD, Research Centre as Principal Scientist, Process Research (bulk actives) at Mahape, Navi Mumbai, India.

Prior to joining Glenmark, he has worked with major multinationals like Hoechst Marion Roussel, now Sanofi, Searle India Ltd, now RPG lifesciences, etc. He has worked with notable scientists like Dr K Nagarajan, Dr Ralph Stapel, Prof S Seshadri etc, He did custom synthesis for major multinationals in his career like BASF, Novartis, Sanofi, etc., He has worked in Discovery, Natural products, Bulk drugs, Generics, Intermediates, Fine chemicals, Neutraceuticals, GMP, Scaleups, etc, he is now helping millions, has 9 million plus hits on Google on all Organic chemistry websites. His friends call him worlddrugtracker.

He has good proficiency in Technology transfer, Spectroscopy, Stereochemistry, Synthesis, Polymorphism etc.

He suffered a paralytic stroke/ Acute Transverse mylitis in Dec 2007 and is 90 %Paralysed, He is bound to a wheelchair, this seems to have injected feul in him to help chemists all around the world, he is more active than before and is pushing boundaries, he has 9 million plus hits on Google, 2.5 lakh plus connections on all networking sites, 20 Lakh plus views on dozen plus blogs, He makes himself available to all, contact him on +91 9323115463, email amcrasto@gmail.com, Twitter, @amcrasto

He lives and will die for his family, 90% paralysis cannot kill his soul. Notably he has 9.5 lakh views on New Drug Approvals Blog in 211 countries..................click here

He appreciates the help he gets from one and all, Friends, Family, Glenmark, Readers, Wellwishers, Doctors, Drug authorities, His Contacts, Physiotherapist, etc

OLD BIO

DR ANTHONY MELVIN CRASTO Ph.D , Born in Mumbai in 1964 and graduated from Mumbai University, Completed his PhD from ICT ,1991, Mumbai, India in Organic chemistry, The thesis topic was Synthesis of Novel Pyrethroid Analogues,

Currently he is working with GLENMARKPHARMA LTD, Research centre as Principal Scientist, Process Research (bulk actives) at Mahape, Navi Mumbai, India.

Prior to joining Glenmark, he worked with major multinationals like Hoechst Marion Roussel, now Sanofi Aventis, & Searle India ltd, now RPG lifesciences, etc. He has worked in Basic research, Neutraceuticals, Natural products, Flavors, Fragrances, Pheromones, Vet Drugs, Drugs, formulation, GMP etc. He has total 29 yrs exp in this field, he is now helping millions, has million hits on google on all organic chemistry websites.

He has hands on experience in initiation and developing novel routes for drug molecules and implementation them on commercial scale over a 25 year tenure, good knowledge of IPM, GMP, Regulatory aspects, he has several international drug patents published worldwide .

He suffered a paralytic stroke in dec 2007 and is bound to a wheelchair, this seems to have injected feul in him to help chemists around the world, he is more active than before and is pushing boundaries, he has one lakh connections on all networking sites, He makes himself available to all, contact him on +91 9323115463, amcrasto@gmail.com, Twitter @amcrasto