Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Applications

Specificity and Use

ELISA: In a sandwich ELISA (assuming 100 ul/well), when used as a capture antibody at a concentration of 2-4 ug/ml, this antibody will detect at least 100 pg/ml of recombinant human BMP-7/OP-1 when used with biotinylated antigen-affinity purified anti-hBMP-7/OP-1 (LS-C104294) as the detection antibody at a concentration of approximately 0.5-1 ug/ml.

Packaging

Presentation:

Lyophilized from PBS

Reconstitution:

Sterile water

Storage:

Store Lyophilized at room temperature up to 1 month; Reconstituted for up to two weeks at 2-8°C. Aliquot and freeze at -20°C for long term storage. Avoid freeze/thaw cycles.

Description: The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site.