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The actress, who has portrayed doctor Cristina Yang since the ABC series premiered in 2005, will exit after the upcoming tenth season, E! News has confirmed.

"It's been a great privilege to play the character of Cristina Yang on 'GA' and I am both sad and excited to see where this, her final season will take her," Oh says in a statement. "It was an emotional and deeply creative decision for me and I feel fully supported by Shonda [Rhimes] and the writers. It's so rare in an actor's life to be able to explore and grow a character so fully, so completely. I am profoundly grateful to everyone at 'GA' for the opportunity. I'm excited to celebrate and cherish every moment of my final season on 'GA' with the fans who have made it all possible."

While there are no details about how her character will exit the series, Rhimes says that she will get a goodbye worthy of her years on the drama.

"One of the best days of my life as a writer happened the day Sandra Oh walked in my door to audition and forever changed the course of 'Grey's Anatomy' with her brilliant, nuanced portrayal of Cristina Yang," Rhimes says. "Over the past ten seasons, I have been made better by Sandra's trust, faith and friendship and I can't quantify how grateful I am for her collaboration on a character we both love so deeply. This year is going to be bittersweet for us--we're both going to savor every moment of Cristina Yang and then we're going to give her the exit she deserves. And when Sandra walks out of my door, 'Grey's Anatomy' will be once again be forever changed."