How To Arrange Furniture in Open Layout Studio?

Q: My girlfriend and I are moving into a 546 square foot apartment, and we are having a hard time finding the right setup since we have never had such an open layout before. We have a queen bed, loveseat, 46" flat screen, and a large work desk we are considering putting outside tucked away on the patio if it doesn't fit inside. Please help! We will also be adding a coffee table or ottoman with storage soon, so please feel free to suggest ideas. Oh yeah: two bikes will also need space :/ Thank you!!