Simple Guard 3: Any Side effects?

This is a discussion on Simple Guard 3: Any Side effects? within the Dog Health forums, part of the Keeping and Caring for Dogs category; Hi,
I got Simple Guard 3 from my vet. This is the second time I'm using it on my dog and for the past hour ...

I got Simple Guard 3 from my vet. This is the second time I'm using it on my dog and for the past hour she's been acting funny. Pacing, rubbing herself on things, panting, mostly pacing. She also randomly peed on the floor and this was AFTER we took her on a walk (because she was pacing) and she went pee twice and pooped. It just seems strange. She seems to be sleeping at the moment, so maybe if was just a slight reaction to the medicine, but I wanted to see if anyone else has used this product and what their experience was with it.

There seems to be nothing online about this product. The one site that says that it has reviews is not working.

I've never heard of it but it definitely sounds like she's having a poor reaction to it. I'd switch her to something else. There are plenty to choose from-- I've heard of the fewest side effects from Frontline Plus.

I've never heard of it but it definitely sounds like she's having a poor reaction to it. I'd switch her to something else. There are plenty to choose from-- I've heard of the fewest side effects from Frontline Plus.

I agree with the fronline being the least toxic. If your dog has a reaction like that I would not use it again. I have seen posts on this forum and others where the vet says that it is not the product. If it is a topical product bathe the dog and get it off. Wait a few days for the dog to recover and then use frontline and see if it happens again. If it does then you might want to try something natural like thisDanger of Chemical Pest Control Products - Safe Alternatives

I am having the same problem with my bichon-poodle. I gave it to her on Monday. She is restless, rubbing, jerking movements, panting, generally miserable. I took her to the vet on Wednesday. She said they have had a couple others like this. They gave her a bath in dish soap per the manufacturer's advise and I picked her up. This is Thursday night and she is still having the problems just as bad. The doctor gave her benedryl pills but it doesn't seem to help at all. I called the manufacturer using the 877 number on the box and they took the report. The vet refunded my money and gave me the bath for free but my dog is really miserable and different personality too. Please keep me posted and I will do the same. Kathy

I gave the first fisher to my Maltese yesterday and he's been restless and panting ever since. I decided to bathe him because nothing else about his diet or environment has changed. So far he has calmed down. I wil be switching back to frontline. Thanks for the info it helped lessen my anxiety to see others haf similar issuses with simple guard.Posted via Mobile Device

We have 2 Bichons and I gave them their first dose last week. The 4 yr old male has had problems that are almost identical to those Kathykuoppala has described. The 3 yr old female has not been as obviously effected, but she has had a similar reaction. The first washing has not helped much.

AWFUL PRODUCT! I used it on my Cockapoo Jimmy. It went on greasy and his back got red. He was rolling on and biting his back for 4 days since I applied it, and he constantly shakes like he is wet. The VCA vet said to call back if it went on for a week, but I'm not going to wait another minute. Based on everything I've read, this product should be recalled.

The product is not an awful product and does not need to be recalled. There is a huge difference between Frontline and Simpleguard 3. The difference is in how they are actually spread through the body. One common reaction that dog owners report is my pet is shaking and rubbing on things and pacing. Some have also claimed that it seems like a seizure. Although that is possible with any topical product, it's called translocation. The product is working its way into the skin and body by "moving" through the layers of the skin. Most of the time after applying it twice your pet shouldn't have any reaction to it. This would also explain why even washing the location after application and the progress of signs would indicate the signs are still present. Simpleguard 3 is a fairly new product but is actually similar almost exact to Vetra 3D. The other difference between Simpleguard 3 and Frontline is that Frontline is only a preventative where as Simpleguard 3 is a preventative AND a repellant. In order to be a repellant some of the product needs to stay within the layers of the skin and that is why your pet has that reaction. Before you know, please don't knock the product. I'll be happy to answer any other questions about it.

Frontline works by translocation as well, so there isn't actually a difference at all in how they are spread throughout the body... and anectdotally there are few reactions to the Frontline (unless you buy knock-off Frontline).

What do you know about Simpleguard 3 Holly? Have you used it? What parasites does it protect against? What is the main ingredient versus Frontline? Why is it that after washing the area where frontline was applied any "adverse reactions" will cease? And there is a huge difference in how they work in the body. As well as the difference in ingredients.