Pharmacoprophylactic and Pharmacotherapeutic Approaches to Mitigating the Damaging Effects of Ionizing Radiation: Review of Information Sources

Fedir Hladkykh

Abstract

The purpose of the article is to synthesize the scientific points of view on modern approaches to pharmacological correction of radiation damage. Conducting medical treatment, aimed at eliminating the negative effects of exposure to ionizing radiation and accelerating the recovery processes in an irradiated organism requires the mandatory use of anti-radiation agents. Today there is a reasonable division of all anti-radiation drugs into pharmacoprophylactic and pharmacotherapeutic. The means of preventing radiation damage include three classes of drugs – radioprotectors, radio modulators and radio modifiers. Special attention is paid to preparations of early pathogenetic therapy (radiomitigators) and the means of therapy of delayed effects of the radiation factor. The modern classification of the rather wide range of medicines with anti-radiation effects, which greatly complicates the holistic perception of their compartmentalization, taking into account their practical significance in specific scenarios of radiation damage, is compiled.