Where to watch: The debate can be viewed on CNBC and will also be streaming on the network's website. However, users will need to log into their service provider in order to watch the event through CNBC.com or CNBC Pro. An earlier debate at 6 p.m. EDT will feature candidates who haven't gained enough support in recent polls in order to participate in the main event, including former Pennsylvania Sen. Rick Santorum, Louisiana Gov. Bobby Jindal, former New York Gov. George Pataki and South Carolina Sen. Lindsey Graham.

Here's your first look at the #CNBCGOPDebate stage! Full coverage: http://CNBC.com/GOPDebate pic.twitter.com/PablUlhnjp

Wednesday night's event is the third Republican debate of the season and comes right as Carson is taking front-runner Trump's consistent national lead against the other handful of GOP candidates. The billionaire businessman's campaign has been on the offensive mode against Carson's in recent weeks, lambasting the former neurosurgeon for not being conservative enough when it comes to abortion and questioning his religious affiliation.

Donald Trump reacts to being overtaken in the polls by Ben Carson pic.twitter.com/GdTubnBPrZ

As candidates continue to fight for support, voters will certainly be watching the upcoming debates to see where each presidential hopeful stands on the issues. Wednesday night's debate will be the party's last until next month's Fox Business/Wall Street Journal debate on Nov. 10.