A variation of Spikes of Doom: Take a sphere and cover it with spikes and you got yourself a very typical obstacle. Common in video games but also occasionally present in other media. They come in many forms:

HarmoKnight: Do you remember the meteorites that dropped in the second cutscene? Some did not hatch, and now they are rolling, spiked obstacles, big and small. Oh, and don't try jumping over the big ones. They only deal damage.

Kickle Cubicle: One enemy is an invincible spinning spike ball that likes to hug walls.

Kingdom Hearts 3D: The Drill Sye and Cera Terror dream eaters can transform into one and roll into their foes. They're also completely immune to most physical attacks in this state, even unblockable ones.

The Kirby series has Gordo which is a living and invincible version of a spikeball.

Liero: Features spike balls as a weapon - a very tricky, but also potentially very destructive weapon. Players who use them are known as "spikeballers".

Loco Roco series has Togeh which is a black ball of spikes commonly found on surfaces. There is also an alive version of it.

Mega Man 2: Bubble Man's stage has a lot of them. In 9, one type of spikeball is even an enemy.

Pokémon: The Grass/Steel Pokemon Ferroseed and its evolution Ferrothorn◊ from Black and White. Both are spiky metal plants, and Ferrothorn pretty much fits all the criteria at the top of the page (alive, hanging, spins, on chainsvines). Obviously, using a contact move on either of them will result in the attacker taking damage.

Uses spikeballs extensively. They are a rather common attack of many of the bosses in the series. Some of the spikeballs can be seen in environment spinning or mid-air. Also, some enemies, like Orbinaut, have spikeballs.

Sonic Colors introduces Pink wisps that allows Sonic to turn into one of these that can climb walls and ceilings.

On a more Meta level, Sonic himself is one of these most the time, being a hedgehog and all. He's covered in spikes, and all his attacks require him to roll into a ball, often causing the doom of Dr Eggman/Robotnik's machinery.

There's also Spiny eggs, which are thrown by Lakitus, and will either turn in Spinies (red), bounce on the ground (green), or explode (yellow); as well as light green enemies called Spikes, which puke up spiked balls and throw them at the player.

In the spinoffs there are various types of these. Yoshi's Island has blue spike balls called Thorns that kill Yoshi in one hit and can be destroyed by eggs, and Wario Land 4 and Shake Dimension have spiky mines and mine like stationary enemies which look and act like this trope as well.

Terraria has these as a throwable weapon. As well as perpetually rotating ball-n-chain's spawning in dungeons.

Trine loves spiked balls. Rolling, hanging from chains, falling out of trap doors, floating like naval mines, I don't think there was a single level that didn't have one.

Vectorman: The first boss has spikes attached to its wings. Level 3 also features spikeballs, although they may be sea mines.

Valis II has spiked balls that mostly move back and forth along straight lines. They can be temporarily stopped, but not destroyed.

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