I would think that if you have multiple people sitting around a large table, that this would make some players focus on the people sitting right next to them, because it will be harder for some to see opponent's cards at the greater distances with a bigger table.

If the cards will look better because of more detailed printing due to the larger size, that may be an advantage for some, but it wouldn't get me to buy another edition.

I still consider the original edition set in the black plastic case that I have, playable, so an edition with larger cards may not be targeted at me anyway.

Oh, absolutely, the original edition is still playable, with Jeff George's great B&W cartoons. (One of which, you notice, became the company logo.) But some of us can't see those cards any more, even if they belong to the player right next to us.

I am in the "larger cards" camp. I don't care if this edition plays nicely with older ones, because the groups that have been replaced simply don't fit into the modern zeitgeist. Nobody cares who controls MTV anymore, for example. Its perceived influence is long-gone. Now, YouTube and its mix of the banal and horrifying, that's a current social influencer!

For visual and table appeal, perhaps make the Illuminati cards tarot-sized and keep the rest normal card size? That way, the Illuminati would dominate the power structure. They're never included in the deck and don't need to be shuffled either.