The herbaceous plant Carthamus tinctorius (Safflower), belonging to the Asteraceae family, has been used in traditional Chinese medicine to invigorate the blood and release stagnation, to promote circulation and menstruation (Pharmacopoeia of PRC 2010) and to treat neuropsychological disorders such as major depression (Zhao et al.

Carthamus tinctorius L, as a well-known TCM which is able to active blood circulation, remove blood stasis and relieve swelling and edemas, is extensively used for the treatment of cirrhosis, cerebrovascular and cardiovascular diseases (Wagner et al.

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