Replication between S/4HANA 1610 FPS01 and 1610 FPS00 - CAL

Is it possible to make my 1610 FPS01 appliance high-available by deploying a 1610 FPS00 appliance (everything running in Azure with CAL)? I will use the system replication for the DB, but what about NetWeaver and BI VM?

And what about hosts names? I will have to modify all the hosts names on the 2nd appliance, right?