TELL UR InTErn not to loaf around
(culture on potassium tellurite agar and Loeffler's coagulated blood serum)
They will become gray or black in 24 hours on K-tellurite. Loeffler's will stain with methylene blue

What is the treatment for diphtheria?

1) Antitoxin
2) Penicillin or erythromycin
3) DPT vaccine

What disease does Listeria monocytogenes cause?

Meningitis, usually in neonates (3rd behind E. coli and group B strep) and immunocompromised

Why does Listeria thrive in neonates and immunocompromised?

They can live in macrophages if they are not activated by cell-mediated immunity (facultative intracellular organisms)

What are the signs on lumbar puncture of a bacterial meningitis?

CSF has high number of neutrophils, protein, low glucose, and my reveal gram-positive rods)

What is the treatment for Listeria?

Ampicillin or trimethoprim-sulfamethoxazole

What are the only pathogenic gram-negative cocci?

Neisseria meningitidis and gonorrhoeae

What are the virulence factors of Neisseria meningitidis (meningococcus)?

1) gram-negative rods
2) Zoonotic diseases
3) Very virulent - penetrate any body area
4) Facultative intracellular organisms, leave delayed hypersensitivity (indurated skin at site of insertion)
5) Treat with an aminoglycoside (gentamicin or streptomycin) or doxycycline given for a long time

What organism causes bubonic plague?

Yersinia pestis

What disease is common in meat-packers, veterinarians, farmers, and travelers who consume dairy products in Mexico.

Brucellosis

What organism most often infects cat or dog bites?

Pasteurella multocida

What antibiotic do you treat Chlamydia with?

Erythromycin (eyedrops given to newborns) or tetracycline
(no peptidoglycan layer, which is target of penicillin)