..There was no evidence of coumarin or mitomycin C treatment related cytotoxicity to bone marrow cells. The results of this study demonstrate that coumarin is negative in the mouse in vivo micronucleus assay...

Toxicological profile of diethyl phthalate: a vehicle for fragrance and cosmetic ingredients

..02 mg/kg/d, resulting in a margin of safety >2600, when marked differences in dermal absorption between rats and humans are considered. Under normal fragrance use conditions, PEA is not a developmental toxicity hazard for humans...

In vitro penetration and subchronic toxicity of alpha-methyl-1,3-benzodioxole-5-propionaldehyde

..This study is designed to confirm the No-Observed-Effect-Level for induction of dermal sensitization in a normal human population...

Disposition and excretion of 14C-AHTN (7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthalene) and 14c-hhcb (1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-cyclopenta-gamma-2-benzopyran) after intravenous administration to Sprague-Dawley rats and dom

..Components found in the urine of the 2 species were qualitatively similar but quantitatively different. Both AHTN and HHCB were completely metabolized and excreted. No unchanged parent compound was detected in rat or pig urine. ..

..67, 1.49 (aerosol) and 1.51 (pump), 1.24, 1.11, 1.37, and 1.3, respectively. This study provides current exposure information for commonly used products which will be useful for risk assessment purposes...

B220 analysis with the local lymph node assay: proposal for a more flexible prediction model