“Hopefully, her resignation will mark the end of the Reefer Madness era at the DEA,” Dan Riffle, director of federal policies at the Marijuana Policy Project, told The Hill.

At times, she clashed with members of Congress for her stridently anti-pot views. Here’s a video of U.S. Rep. Jared Polis, D-Colorado, trying to find out if she thought heroin and meth are more harmful than pot.