Wit, according to MTC, "follows a brilliant and exacting poetry professor (Tony and Emmy Award winner Cynthia Nixon) as she undergoes experimental treatment for cancer. A scholar who devoted her life to academia, she must now face the irony and injustice of becoming the subject of research."

The play had its New York premiere in 1998 receiving universal acclaim and ran Off-Broadway for over 500 performances. It was the most-honored play of the season garnering the Pulitzer Prize for Drama and was named Best Play by the New York Drama Critics Circle, the Drama Desk Awards, the Outer Critics Circle Awards, the Drama League, and the Lucille Lortel Awards. This is Edson's only play. Even at the height of her fame, she said she had no wish to pursue a playwriting career. Her career is teaching elementary school students.