..Investigation of additional potentially important neurotransmitter receptors, such as the opioid and cannabinoid receptors, may result in further improvements in antiemetic control and quality of life in coming years...

New developments in the management of chemotherapy-induced emesis: do they impact on existing guidelines?

..However, the results do not appear as successful as for highly emetic standard-dose chemotherapy...

New directions in supportive care

Steven M GrunbergSupport Care Cancer 13:135-7. 2005

..Even symptoms such as fatigue and overall outlook may be defined in terms of appropriate enzymatic pathways. Evaluation and application of these advances in basic science are leading directly to new directions in supportive care...

Efficacy and tolerability of aprepitant for the prevention of chemotherapy-induced nausea and vomiting in patients with breast cancer after moderately emetogenic chemotherapy

..This is the first study in which the NK(1)-receptor antagonist, aprepitant (APR), was evaluated for the prevention of chemotherapy-induced nausea and vomiting (CINV) with moderately emetogenic chemotherapy...