Trentino-Alto Adige is Italy's northernmost wine region, located right on the Italian border with Austria. Although once dominated by the local Lagrein and Schiava varieties, in the 21st Century, its wines are increasingly made from well-known international varieties such as Pinot Grigio and Chardonnay.

Due to its complex geopolitical history, Trentino-Alto Adige is composed of two autonomous provinces: Trentino and Alto Adige. Trentino is almost entirely Italian speaking, while Alto Adige has a predominantly German-speaking population, who know their province by the name Sudtirol (South Tyrol in English). This is due to the region's former status as part of the Austro-Hungarian Empire, from which it was re-claimed by Italy in 1919.