NBA Picks: Portland Trail Blazers vs. Los Angeles Lakers

The Los Angeles Lakers are 20-5 all-time against the Portland Trail Blazers at the Staples Center during regular-season play. That is important to consider when making your NBA picks on Friday night, as the two teams tip things off at 10:30 p.m. ET.

Sports bettors will find that the Lakers are nine-point home favorites in the pro basketball odds (courtesy of SBR Forum), while the total sits at 202.5 in the market.

Let's take a closer look at this Western Conference matchup from a betting perspective while offering up a total prediction along the way.

Los Angeles Lakers

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The Los Angeles Lakers have alternated wins and losses over their last seven games, but they're coming off a convincing 113-99 victory over the Boston Celtics as 6.5-point home favorites on Wednesday night.

Sports bettors will find that the Lakers are 6-6 against the spread when favored by 6.5 to 9.0 points at the Staples Center this season, while the OVER is 7-5 in that situation.