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Antihistamines for Morning Sickness

Topic Overview

Certain antihistamines such as dimenhydrinate or doxylamine, taken as your doctor advises, may relieve morning
sickness.footnote 1 Doxylamine (Unisom SleepTabs) is available over-the-counter. If one of these
antihistamines alone does not relieve your morning sickness, you can try taking
it with vitamin B6.footnote 1 Talk to your doctor about the right dose.

Note: Do not confuse Unisom SleepTabs with Unisom SleepGels, which contain
a different medicine.

A prescription medicine that combines doxylamine and vitamin B6 in one medicine (called Diclegis) is also available to treat morning sickness.

Common side effects of these medicines may include:

Drowsiness.

Dry mouth, nose, or throat.

Stomach upset.

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