Aim: The aim of the study was to explore and describe the perceptions and experiences of rape survivors who were receiving Post Exposure Prophylaxis at a regional hospital. Methodology: A phenomenological approach was used to explore the phenomena, of rape survivors' perception and experiences concerning the Post Exposure Prophylaxis (PEP) they received. The study was conducted in R.K.Khan Hospital, in an Outpatient Department in a gynaecology clinic. This is the regional hospital located in Chatsworth, in the Inner Outer West of Ethekwini District. The sample comprised of ten female rape survivors who were receiving Post Exposure Prophylaxis. Data was collected by means of face-to-face interviews using an interview guide. Interviews were lasting thirty to forty minutes long per participant. The researcher applied the principle of theoretical saturation of data and a total of ten participants were included in the study. All interviews were tape recorded and transcribed verbatim. Data was analysed manually using the Editing Analysis Style. Findings: The results of this study indicated that PEP is the new service to rape survivors and this evoked that when you are being raped you face a risk of range of immediate, medium, and long term health problems; physical, and psychological problems. The rape survivors described a number of emotions and physical reactions that they experienced when they were receiving PEP after rape, which were negative and positive reactions. Most experiences they faced indicated that they benefited from the PEP program, because they gained knowledge, got support from care providers and major diseases and complications were prevented by offering the Post Exposure Prophylaxis A number of recommendations were suggested for the provision of PEP program to the community that is for nursing practice, management and education, the policy makers and for future research in an 'attempt to prevent major complications and health problems that occur in rape survivors.