RT Journal Article
SR Electronic
T1 A Trypanosome Structure Involved in Transmitting Cytoplasmic Information During Cell Division
JF Science
JO Science
FD American Association for the Advancement of Science
SP 610
OP 612
DO 10.1126/science.1063775
VO 294
IS 5542
A1 Moreira-Leite, Flávia F.
A1 Sherwin, Trevor
A1 Kohl, Linda
A1 Gull, Keith
YR 2001
UL http://science.sciencemag.org/content/294/5542/610.abstract
AB African trypanosomes are protozoan parasites that cause sleeping sickness in humans through a tsetse fly vector. The procyclic form ofTrypanosoma brucei has a single, attached flagellum that describes a helical path along the cell from posterior to anterior. During division, a specific flagellum-flagellum connection is elaborated between the new and old flagellum. This connector was present only during cell duplication and was found to be involved in the replication of the helical cell pattern and polarity. This finding implicates the concept of cytotaxis in cell morphogenesis in trypanosomes.