Good data to answer an interesting question. I wonder how often the authors were unable to identify sperm on TESE in these cryptozoospermic men.

jim hotaling

This work is well done and methodologically sound. I wonder if the authors could comment on how use of ICSI, which relies on only one sperm, may bias results. Specifically, since men typically have a population of sperm from a semen sample or TESE procedure, could it be that it was easier for the technician to obtain a more viable sperm from the testicular sample versus the ejaculated one? This is the problem that plagues much of the work in this area and I would be curious to hear the authors thoughts on this issue.

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