Abstract

Background of the study

The present investigation was designed with the intention to formulate versatile 5-fluorouracil
(5-FU) matrix tablet that fulfills the therapeutic needs that are lacking in current
cancer treatment and aimed at minimizing toxic effect, enhancing efficacy and increasing
patient compliance. The manuscript presents the critical issues of 5-FU associate
with cancer and surpasses issues by engineering novel 5-FU matrix tablets utilizing
chitosan- polycarbophil interpolyelectrolyte complex (IPEC).