I'm on Oxynorm instant release liquid 1ml/10mg every hour or can have 4ml/40mg every 4hrs etc also I take Oxycodone 4 x 20mg tablets (slow release) every 12 hours. I'm wondering if anyone else is on these and how do they find them? I started on the oxynorm at 20mg and because I've got tolerant they have to build me up 10mg (1ml) at a time. I also started on 20mg oxycodone twice a day so I've been doubled up then doubled again to make it so I'm on 160mg in 24hrs. Does anyone else who's on these find they need their dose upping often? Also has anyone tried anything else? X