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Re: What's the meaning of the conversation

I have some words here hard understand when I learning English by reading Garfield comics:

1, Who knows what the future holds?
Less of this, he refers to something he doesn't like so he doesn't want to experience it in the future I hope

If I assume that 2 and 3 are in the same cartoon:
2,Maybe medical science will make major advances

3,Like curing those little floaty specks at the edge of your vision
and the big one in the middle of mine 'specks' - occasionally vision has very small dots which appear to float in front of our eyes - whoever said this hopes that medical science will find a cure for this. The person he is talking to (Garfield?) is the person (big speck) he sees - he is trying to make a joke and suggest he needs a cure.

Can anyone explain for me? Thanks

Hope that is a little clearer - remember the language will not be as simple since it's supposed to be funny. There will be some 'playing' with the meaning of words.