It seems that a higher percentage of video games (as compared to movies, TV) skew towards a sci-fi universe. Why do think that is?

In science fiction a key concept is exploration and discovery. This really lends itself to interactive entertainment as it is a more personal experience. In other words, the audience is taking the role of director and the star, which means they are both discovering and shaping the experience. A good example for me personally was the first time I set foot on Luna, the Earth's moon, in Mass Effect. I looked up in the sky and could see the Earth - that was a pretty incredible experience; it made me feel like I was part of the NASA Apollo program!

I'll leave it up to you to figure out how "taking the role of director and the star" equates to "I looked up in the sky and could see the Earth".

The new interface is pretty PC-centric, how much of it will you be able to roll into Mass Effect 2?

Each platform has inherent strengths. The Xbox 360 control is really strong in the fact that it is very easy and intuitive to control. Comparing the Xbox 360 version versus the PC, we are looking at two different audiences with different expectations and needs. That being said, I really like what the team has done with the PC version and we are looking at implementing mechanics in future Mass Effect products where they make sense. However, we'll continue to support our fans on both PC and Xbox 360 in the future, so both SKUs need, and will have, different core interfaces.