Humoral response revealed significantly higher total Igs, IgG and IgM titers at days 7th and 14th post primary and secondary injections of sheep red blood cells in the experimental chickens administered with AXs as compared to those of control group.

The percent protection and daily weight gains were significantly higher in the chickens of experimental groups as compared to control.

Mean oocyst per gram of droppings and lesion scores were significantly higher in control group as compared to chickens in the experimental groups.

The differences in organ body weight ratio of all the lymphoid organs were statistically non-significant between experimental and control groups except thymus and caecal tonsils.

Conclusion In conclusion, AXs showed both immunostimulatory and protective effects against coccidiosis in broiler chickens.

Oral administration of Arabinoxylans enhanced the natural immunity in broilers.

Eimeria infection in Arabinoxylans administered broiler chickens.

Elicited humoral response against Eimeria species used in challenge experiment.