Currently my all around home defense/carry gun is a S&W Sigma .40, I know those guns catch alot of flak from alot of people, but i've never had a problem with mine... the trigger pull is heavy but that don't bother me.
In the perfect world, my HD setup would be some type of .45 1911 in addition to a Saiga 12 gauge

PT92 on my side of the bed (9mm) and .410 shotgun on her's. I like the handgun because of the manueverability. I can just about see my front door from where my head lays (small, one-bedroom apartment), so if someone starts kicking that in, I might only have a few seconds to get ready before they are coming my way. With my 9mm, all I have to do is reach to the nightstand and grab it. With a shotgun, especially with tired muscles, it is much more difficult to pull it up and orient it for firing in a short amount of time.

But shotties are probably the safest and simplest to use cuz they don't go through walls super well and they have a good spread on them if you have a short barrel without a choke, you never know you may miss once.

While it is true they are going to be the easiest and most devastating HD gun available, a proper defense load will still go through several walls (true, not as well as most pistol or rifle calibers, but you wouldn't want to aim toward your kids, no matter how many walls are between you and them). And, as far as spread, it is relatively neglegible as far as ease of making a successful hit, though it is very good at vastly increasing the damage of a successful hit.

Currently my all around home defense/carry gun is a S&W Sigma .40, I know those guns catch alot of flak from alot of people, but i've never had a problem with mine... the trigger pull is heavy but that don't bother me.
In the perfect world, my HD setup would be some type of .45 1911 in addition to a Saiga 12 gauge

I agree with ya for now thats my night stand drawer gun a smith and wesson sigma 9mm though. the trigger pull doesn't bother me and it always shoots anything i feed it. i got a picatinny rail adapter on it and a laser on that and a stock (for now) ruger 10/22 all i got for now but i'm workin on it

My all around home pistol is a Ruger P94(KP944DC to be exact) in 40 cal. Its never more than an arms length away. Metal frame and good reliability. Not my preferred carry weapon, but thats why its the home weapon. I know its alittle different from most, but a good quality weapon.

I'd get a shotgun, but I live in an apt, and am really worried about stray shots hurting one of the neighbors, as our walls are paper thin.

Soon, I'll be getting a .45 ACP (Springfield XD or 1911, haven't decided yet) for my home defense gun. I've decided that if I'm going to use a pistol, I need to use the best caliber available... I'll probably end up getting some kind of 1911 (Springfield or Kimber with night sites).