Topic Contents

Familial Adenomatous Polyposis

National Organization for Rare Disorders, Inc.

Important
It is possible that the main title of the report Familial Adenomatous Polyposis is not the name you expected.

Disorder Subdivisions

None

General Discussion

Familial adenomatous polyposis (FAP) is a rare inherited cancer predisposition syndrome characterized by hundreds to thousands of precancerous colorectal polyps (adenomatous polyps). If left untreated, affected individuals inevitably develop cancer of the colon and/or rectum at a relatively young age. FAP is inherited in an autosomal dominant manner and caused by abnormalities (mutations) in the APC gene. Mutations in the APC gene cause a group of polyposis conditions that have overlapping features: familial adenomatous polyposis, Gardner syndrome, Turcot syndrome and attenuated FAP.

Supporting Organizations

American Cancer Society, Inc.

250 Williams NW St

Ste 6000

Atlanta, GA 30303

USA

Tel: (404)320-3333

Tel: (800)227-2345

Website: http://www.cancer.org

CORE

3 St. Andrews Place

London, NW1 4LB

United Kingdom

Tel: 2074860341

Fax: 2072242012

Email: info@corecharity.org.uk

Website: http://www.corecharity.org.uk

Cancer Support Community

1050 17th St NW Suite 500

Washington, DC 20036

Tel: (202)659-9709

Fax: (202)974-7999

Tel: (888)793-9355

Website: http://www.cancersupportcommunity.org/

Cancer.Net

American Society of Clinical Oncology

2318 Mill Road Suite 800

Alexandria, VA 22314

Tel: (571)483-1780

Fax: (571)366-9537

Tel: (888)651-3038

Email: contactus@cancer.net

Website: http://www.cancer.net/

Desmoid Tumor Research Foundation

P.O. Box 273

Suffern, NY 10901

Tel: (914)262-6595

Fax: (845)369-8302

Email: marlene@dtrf.org

Website: http://www.dtrf.org

Familial GI Cancer Registry

Mt. Sinai Hospital

Joseph and Wolf Lebovic Health Complex

Ontario, M5T 3L9

Canada

Tel: 4165964200

Fax: 4165855024

Email: zcc@mtsinai.on.ca

Website: http://www.mountsinai.on.ca/care/fgicr

Friends of Cancer Research

1800 M Street NW

Suite 1050 South

Washington, DC 20036

Tel: (202)944-6700

Email: info@focr.org

Website: http://www.focr.org

Genetic and Rare Diseases (GARD) Information Center

PO Box 8126

Gaithersburg, MD 20898-8126

Tel: (301)251-4925

Fax: (301)251-4911

Tel: (888)205-2311

Website: http://rarediseases.info.nih.gov/GARD/

Johns Hopkins Hereditary Colorectal Cancer Registry

Johns Hopkins Hospital

1830 East Monument Stree

Baltimore, MD 21205

Tel: (410)955-2635

Fax: (410)614-8337

Tel: (888)772-6566

Email: hccregistry@jhmi.edu

Website: http://www.hopkins-gi.org

M. D. Anderson Cancer Center Hereditary Colorectal Cancer Registry

Dept of Gastrointestinal Oncology

1515 Holcombe Boulevard

Houston, TX 77030

Tel: (713)792-3245

Fax: (713)745-1163

Tel: (877)632-6789

Email: hcc-editor@mdacc.tmc.edu

Website: http://www.mdanderson.org/about-us/index.html

National Cancer Institute

6116 Executive Blvd Suite 300

Bethesda, MD 20892-8322

USA

Tel: (301)435-3848

Tel: (800)422-6237

Email: cancergovstaff@mail.nih.gov

Website: http://www.cancer.gov

OncoLink: The University of Pennsylvania Cancer Center Resource

3400 Spruce Street

2 Donner

Philadelphia, PA 19104-4283

USA

Tel: (215)349-8895

Fax: (215)349-5445

Email: hampshire@uphs.upenn.edu

Website: http://www.oncolink.upenn.edu

Rare Cancer Alliance

1649 North Pacana Way

Green Valley, AZ 85614

USA

Website: http://www.rare-cancer.org

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). For a full-text version of this report, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

Last Updated: 1/27/2014Copyright 2014 National Organization for Rare Disorders, Inc.

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