Deoxyuridine 5’-triphosphate nucleotidohydrolase ; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (145 aa)

0.997

R2601_14420

DNA polymerase III subunit beta ; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (372 aa)

0.987

R2601_26661

Adenylate kinase ; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP (228 aa)

0.981

R2601_09265

Adenylate kinase ; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP (192 aa)

Nucleoside-2-P kinase ; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (140 aa)

0.979

R2601_15447

DNA polymerase I (935 aa)

0.970

R2601_12990

Glutamate synthase, large subunit (1537 aa)

0.893

tmk

dTMP kinase ; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (208 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

R2601_09265

R2601_09932

R2601_09265

R2601_09932

Adenylate kinase ; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP

Deoxyuridine 5’-triphosphate nucleotidohydrolase ; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA

0.816

R2601_09265

R2601_15447

R2601_09265

R2601_15447

Adenylate kinase ; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP

DNA polymerase I

0.658

R2601_09265

R2601_18628

R2601_09265

R2601_18628

Adenylate kinase ; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP

Adenylate kinase ; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP

Ribonucleotide-diphosphate reductase alpha subunit

0.981

R2601_09265

gmk

R2601_09265

R2601_24894

Adenylate kinase ; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP

GMP kinase ; Essential for recycling GMP and indirectly, cGMP

0.768

R2601_09265

ndk

R2601_09265

R2601_24679

Adenylate kinase ; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP

Nucleoside-2-P kinase ; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate

0.875

R2601_09265

tmk

R2601_09265

R2601_19604

Adenylate kinase ; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP

dTMP kinase ; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis

0.788

R2601_09932

R2601_09265

R2601_09932

R2601_09265

Deoxyuridine 5’-triphosphate nucleotidohydrolase ; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA

Adenylate kinase ; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP

0.816

R2601_09932

R2601_14420

R2601_09932

R2601_14420

Deoxyuridine 5’-triphosphate nucleotidohydrolase ; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA

DNA polymerase III subunit beta ; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA

0.985

R2601_09932

R2601_15447

R2601_09932

R2601_15447

Deoxyuridine 5’-triphosphate nucleotidohydrolase ; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA

DNA polymerase I

0.716

R2601_09932

R2601_18628

R2601_09932

R2601_18628

Deoxyuridine 5’-triphosphate nucleotidohydrolase ; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA

Deoxyuridine 5’-triphosphate nucleotidohydrolase ; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA

Ribonucleotide-diphosphate reductase alpha subunit

0.997

R2601_09932

R2601_26661

R2601_09932

R2601_26661

Deoxyuridine 5’-triphosphate nucleotidohydrolase ; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA

Adenylate kinase ; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP

0.816

R2601_09932

ndk

R2601_09932

R2601_24679

Deoxyuridine 5’-triphosphate nucleotidohydrolase ; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA

Nucleoside-2-P kinase ; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate

0.980

R2601_09932

tmk

R2601_09932

R2601_19604

Deoxyuridine 5’-triphosphate nucleotidohydrolase ; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA

dTMP kinase ; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis

0.925

R2601_12990

R2601_15447

R2601_12990

R2601_15447

Glutamate synthase, large subunit

DNA polymerase I

0.561

R2601_12990

R2601_24789

R2601_12990

R2601_24789

Glutamate synthase, large subunit

Ribonucleotide-diphosphate reductase alpha subunit

0.893

R2601_12990

gmk

R2601_12990

R2601_24894

Glutamate synthase, large subunit

GMP kinase ; Essential for recycling GMP and indirectly, cGMP

0.514

R2601_14420

R2601_09932

R2601_14420

R2601_09932

DNA polymerase III subunit beta ; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA

Deoxyuridine 5’-triphosphate nucleotidohydrolase ; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA

0.985

R2601_14420

R2601_15447

R2601_14420

R2601_15447

DNA polymerase III subunit beta ; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA

DNA polymerase I

0.998

page 1 of 5

Network Stats

Network Stats analysis is still ongoing, please wait ...

Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: