11-16-11 Integument and Mammary Glands - ZOL 320...

ZOL 320Developmental BioNovember 16, 2011Integument and Mammary GlandsEpidermis and mammary gland development•Cutaneous structures(hair, nails, feathers, talons) are strikingly adaptable for different environments.•Also the epidermis is water impermeable (usually), tough barrier with structures which secrete substances (sweat, sebaceous, and mammary glands for instance)I.Development of the skina.Developmental origin and anatomya.i.Peridermis the first skin to form: Two cell layers, a bumpy thickened epidermis over a basal layer with stem cellsa.i.1.Transient organ and quite permeable unlike the later mature epidermisa.i.2.Basal layer (stratum germinativum) under epidermal layera.i.3.There are peridermis bumps within the epidermal layera.ii.Mature skin development:a.ii.1.Stratification: Two layered with epidermis(ectoderm) over the dermis(mesoderm or NCC in head)a.ii.2.Proliferation and differentiation: Basal stem cells attached to basal lamina make an outer spinous layerof

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