Non-Helicobacter pylori gastritis is common among paediatric patients with inflammatory bowel disease

Alimentary Pharmacology and Therapeutics, 04/27/2012Genta RM et al.

Helicobacter–negative gastritis and duodenitis occur significantly more often in paediatric inflammatory bowel disease (IBD) patients than in non–IBD controls, as well as in adult IBD patients. Such upper gastrointestinal inflammation appears to be particularly common in patients with Crohn's disease.

Methods

From a computerised database of surgical pathology reports, the authors selected 344 IBD patients and 4241 non-IBD controls between the age 0 and 21 years, who underwent colonoscopy and oesophago-gastro-duodenoscopy with biopsy results from both procedures.