Could autoimmune disease be a reason for multiple miscarriages?

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Question: Hello, I recently miscarried at 5 weeks, threatened mc x 1 week followed by spontaneous loss. No reason determined, however the tissue I passed look identical to tissue I psssed 3 years prior during a late period - almost like a small rubber balloon with all the air out. My OB said that was likely a mc as well. I have to insert 100 mg Progesterone vaginally now on cycle day 12 in an effort to prevent further loss. I do have a positive ANA, no further DX. Could this be contributing to the multiple losses?

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