Mickelson played with his third partner in as many matches, and he was as good as ever. The American side played bogey-free with five birdies, although it did trail briefly when Villegas made a 12-foot birdie at the third. The International side three-putted the next hole, Mickelson hit wedge to a foot on the fifth and the Americans were on their way.

The teams halved the opening hole with birdies, but on the American side kept up the pace by playing bogey-free in this awkward format. The match was all square at the turn when Furyk made a 15-foot birdie putt, and they made it 2-up on the 12th when Furyk rolled in another birdie from 15 feet. Els and Scott failed to make birdie after the eighth hole, and the match ended on the 15th hole when Els and Scott combined to three-putt from 25 feet.

The Americans won the first two holes with birdies, then followed with two straight bogeys to square the match. Singh and Allenby combined for back-to-back birdies starting at the par-5 fifth to build a 2-up lead, and they stayed in control until the final few holes. The International team had a 2-up lead with four holes to play when it made bogey at the 15th. They halved the next two holes, but Mahan hit his approach to 35 feet on the par-5 18th, and the International team failed to make birdie.

Stricker opened with a birdie putt, but the lead vanished quickly. Woods and Stricker made their first bogey of the Presidents Cup on the second hole, fell behind for the first time at the Presidents Cup on the fifth hole when Weir hit his wedge to 2 feet, and then fell apart on the greens. They missed four putts inside 8 feet in a six-hole stretch. The International team had a 1-up lead with two holes to play when Woods made a 25-foot birdie putt, and Weir missed his birdie putt from 5 feet. With the match square, Woods hit 3-iron to 8 feet, and the eagle – and match – was conceded when the International side failed to made birdie from a bunker.

The Americans didn't make a birdie until the 12th hole, and by then it was too late. Yang and Ishikawa controlled the scoring, mixing birdies and pars at the start until taking the lead for good on the par-5 fifth hole when Yang pitched to 3 feet for birdie and Johnson missed a 10-foot putt that would have tied it. Perry missed a 5-foot par putt on the eighth, and Ishikawa knocked in an 18-foot birdie putt on the 10th for a 3-up lead. The Internationals closed it out with Ishikawa's 7-foot birdie on the 16th.

The Americans never trailed, and they never had it easy, either. Cabrera and Scott bogeyed the second hole and Furyk birdied the third for a 2-up lead, only for Cabrera to make birdies on two straight holes to square the match at the turn. Furyk's birdies at the 10th and 13th restored the 2-up lead, and Scott finally pitched in with a 6-foot birdie on the 16th to close the gap. Kim made an 8-foot birdie on the 17th to halve the hole and keep a 1-up lead, and Furyk clinched it with a fairway metal to 15 feet for a conceded eagle.

The International team never trailed, and it was never seriously challenged. Allenby gave the team its first lead with a birdie on the third, another at the par-5 fifth. Ogilvy, winless the first two days and benched in the morning, got in on the act with birdies on the seventh and the 10th as the International team built a 4-up lead. The Americans hung around long enough to make it to the 17th, where Allenby drove the green for a two-putt birdie. Glover was the only American without a point in team matches.

Coming off a missed putt that cost his team victory in the morning, Weir got back on track with a birdie on the opening hole to give the International team a lead it never relinquished. This turned out to be the biggest rout of the afternoon, with Weir adding a birdie on the fourth, Els holing out for birdie from a bunker on the ninth and rolling in a 25-foot birdie putt on the 12th. The Americans didn't win a single hole.

After narrowly winning in foursomes, this match was no contest. Stricker opened the scoring with a birdie to win the third hole, and then he started rolling them in from all over Harding Park – 35 feet on the sixth hole, another long putt on the eighth, yet another on the 10th for a 5-up lead. Woods didn't have to contribute anything. The Asian duo made a late rally, with Ishikawa making two long birdie putts. He couldn't make it three in a row on the 16th, however, where the match ended.

Singh and Clark tag-teamed beautifully with birdies to build a 2-up lead at the turn, and after trading birdies, the International team kept a 2-up lead with seven holes to play. Mickelson cut into the lead with a birdie at the 12th, O'Hair squared the match with a birdie on the 13th, and they halved the rest of the holes. Clark hit it to tap-in range on the par-3 14th, only for Mickelson to roll in a 40-foot birdie to halve the hole. O'Hair made a 3-foot birdie to halve the 17th, and all four players arrived at the 18th with a birdie chance. Clark was 25 feet away and missed, Singh and O'Hair missed from 15 feet, and Mickelson missed his putt from 10 feet.