What it is: Botox, Dysport, and the new Xeomin—all made from variations of botulinum toxin type A—erase wrinkles by blocking the nerve impulses that cause muscles to contract.

The cost: Approximately $400 every three to four months. After 20 minutes, you may be able to return to work; within a week, you'll see full results.

Editor's take: ★★★★★ "Hands down, Botox is the easiest way to get rid of wrinkles. I'd tried everything: laser, Retin-A, chemical peels. Four days after my first injection, the stubborn lines were gone for good, but my face still looks natural."