Showing 1-100 of 186 Results

Current Research and Scholarly Interests
We study how the neural circuitry of the vertebrate retina encodes visual information and performs computations. To control and measure the retinal circuit, we present visual images while performing simultaneous two-photon imaging and multielectrode recording. We perturb the circuit as it operates using simultaneous intracellular current injection and multielectrode recording, and use the resulting large data sets to construct models of retinal computation.

Current Research and Scholarly Interests
Prevention of osteoporosis begins in childhood and adolescence by measures that maximize acquistion of bone mineral during the critical adolescent years. Body mass, calcium nutriture, physical activity, growth and sex steroid hormones, and genetic factors are all thought to be important determinants of bone mass although the relative contribution of each remains controversial.

Current Research and Scholarly Interests
I have trained in both Genito-Urinary Medicine (UK) and Dermatology. This has allowed me to develop a specialty clinic for the diagnosis and management of genital skin disorders. The rest of the time, I see individuals with general dermatology issues.

Current Research and Scholarly Interests
Our laboratory is focused on identifying proteins based upon their ability to alter a variety of cell fate decisions - including mesodermal, endodermal, neural, endothelial, and somitic - within the vertebrate embryo.

Current Research and Scholarly Interests
Dr. Baker's research is in the area of health economics, and focuses on the effects of financial incentives, organizational structures, and government policies on the health care delivery system, health care costs, and health outcomes.

Current Research and Scholarly Interests
I closed my laboratory when I retired in 1998. I continue to do research, chiefly in collaboration with Franc Avbelj, on problems of protein folding energetics, especially peptide backbone solvation, and to write reviews.

Current Research and Scholarly Interests
His research interests include (1) development, assessment, and improvement of novel infectious diseases diagnostics, (2) enhancing the quality of C. difficile diagnostic results, and (3) characterization of M. tuberculosis virulence determinants.

Current Research and Scholarly Interests
Dr. Banerjee is the Director of Endoscopy at the Stanford University Medical Center. His research interests include evaluation of advanced endoscopic procedures (ERCP, choledochoscopy and endoscopic ultrasound) in the diagnosis and management of benign and malignant pancreatic and biliary disease. Additional interests include the development of new endoscopic devices and instruments.

Current Research and Scholarly Interests
My current clinical research involves the development of pathways for the treatment of headache both in the hospital and clinic setting. I also have a strong interest in medication overuse headache and the use of a multi-disciplinary program for treatment.

Current Research and Scholarly Interests
Our lab studies how intricate control of gene expression and cell signaling is regulated on a minute-by-minute basis to give rise to the remarkable diversity of cell types and tissue morphology that form the living blueprints of developing organisms. This research aims to add a new dimension to our understanding of how cells ?know? where to go, when to move and differentiate by employing novel technologies that probe these questions at a highly molecular and nanoscale level. Work in the Barna lab is presently split into two main research efforts. The first is investigating ?specialized ribosomes? and mRNA translation in control of gene expression genome-wide in space and time during development. This research is opening a new field of study in which fundamental aspects of gene regulation are controlled by ribosomes harboring a unique activity that ?select? for specific mRNAs to translate by virtue of unique RNA regulons embedded within 5?UTRs. The second research effort is centered on employing state-of-the-art live cell imaging to visualize cell signaling and cellular control of organogenesis. This research has led to the realization of a novel means of cell-cell communication dependent on a dense network of actin-based cellular extension within developing organs that interconnect and facilitate the precise transmission of molecular information between cells.

Current Research and Scholarly Interests
Advanced imaging, including magnetic resonance imaging, of injury to the developing central nervous system; including fetal, neonatal, infant and young child; and, including nonaccidental injury (e.g. child abuse).

Current Research and Scholarly Interests
In the Microbiology laboratory, we evaluate cutting-edge new technology for rapid diagnosis of infectious diseases, and we work with high-tech companies to help them develop new diagnostic assays at the pre-market stage. We do not perform basic research and we do not have any fellowship support.

Current Research and Scholarly Interests
Magnetic Resonance Imaging and Sonographic diagnosis of fetal anomalies. Focus interest in the diagnosis and conservative (non-surgical and minimal radiation) management of congenital broncho pulmonary malformations. Imaging of appendicitis in children. Sonography of the pediatric testis.

Current Research and Scholarly Interests
We are interested in the mechanism by which bacterial toxins, viruses, and protein aggregates hijack the secretory pathway and kill cells. More broadly, we investigate how diverse stresses (biological, chemical) signal to the apoptotic machinery.

To pursue these interests, we develop widely applicable new technologies to screen and measure genetic interactions; these include high-complexity shRNA libraries, which have allowed the first systematic genetic interaction maps in mammalian cells.

Current Research and Scholarly Interests
Defining the role of matrix metalloproteinases in connective tissue remodeling of the skin.Defining the macromolecular structures of the cutaneous basement membrane zone.Developing methods for delivery of extracutaneous gene therapy in epidermolysis bullosa.

Current Research and Scholarly Interests
Function of Hedgehog proteins and other extracellular signals in morphogenesis (pattern formation), in injury repair and regeneration (pattern maintenance). We study how the distribution of such signals is regulated in tissues, how cells perceive and respond to distinct concentrations of signals, and how such signaling pathways arose in evolution. We also study the normal roles of such signals in stem-cell physiology and their abnormal roles in the formation and expansion of cancer stem cells.

Current Research and Scholarly Interests
Applications of computer graphics to medical imaging, with emphasis on diagnosis of bowel pathology using virtual colonoscopy. Dynamic joint imaging with open Magnetic Resonance Imaging system.

Current Research and Scholarly Interests
Dr. Bejerano, co-discoverer of ultraconserved elements, studies the Human Genome. His research focuses on genome sequence and function in both humans and related primate, mammalian and vertebrate species. He is deeply interested in mapping both coding and non-coding genome sequence variation to phenotype differences, and in extracting specific genetic insights from high throughput sequencing measurements, in the contexts of development and developmental abnormalities.

Current Research and Scholarly Interests
Dr. Bellino also serves as Clinical Associate Professor of Orthopaedic Surgery with specialty interest in hip and pelvis reconstruction. His areas of clinical expertise include: pelvis and acetabulum fractures, periarticular and long bone fractures, malunions and nonunions, hip arthritis, hip dysplasia, and femoro-acetabular impingement. His research interests focus on anatomy and biomechanics of the hip and pelvis as well as surgical treatments for disorders of the hip.

Current Research and Scholarly Interests
Our goal is to understand the mechanisms regulating the development of human systems. Drawing on both pluripotent stem cell biology, hematopoiesis, and immunology, combined with novel high-content single-cell analysis (CyTOF ? Mass Cytometry) and imagining (MIBI-Multiplexed Ion Beam Imaging) we are creating templates of ?normal? human cellular behavior to both discover novel regulatory events and cell populations as well as understand dysfunctional processes such as cancer.

Current Research and Scholarly Interests
My research focuses on improving health care delivery systems for children, adolescents and young adults with chronic illness with a focus on the transition from pediatric to adult-oriented health care.

Current Research and Scholarly Interests
For about 10 years until 2000, my lab's research activities were focused on the mechanism of recombinational repair of double-strand breaks in DNA. We focused our efforts on two model systems: one involved the repair of restriction enzyme cleavages at specific mammalian chromosomal loci and the second explored the biochemical properties of purified yeast Rad51 protein, an essential catalyst for synapsing the broken ends of DNA with an intact homologue of that sequence. We also explored the roles of Rad52 and PRA (single-strand DNA binding protein) in the repair process.

In 2000, I became Emeritus Professor in Biochemistry and stepped down from the Directorship of the Beckman Center. Much of my activities since then have been involved in writing a biography of the genetics pioneer George Beadle, published in 2003, plus articles for other publications elaborating on Beadle's legacy for today's science. Over the years I have been and continue to be an activist in public policy issues affecting biomedical issues, e.g. recombinant DNA and more recently, issues concerning embryonic stem cells.

Current Research and Scholarly Interests
My research has involved the use of new technologies to create different types of patient-doctor transactions. I am also interested in how these new transactions impact clinical care processes. Current work includes the evaluation of a patient portal for children with cystic fibrosis, the use of telemedicine to bring asthma experts into the schools and the attitudes of teens and parents about the use of a secure patient portal for teens.

Current Research and Scholarly Interests
We use genetic, genomic and cell biological approaches to study cell fate acquisition, focusing on cases where cell fate is correlated with asymmetric cell division.

Current Research and Scholarly Interests
1. Role of the G protein coupled receptors in regulating mitochondrial structure and function.2. Differences between R and L ventricular responses to stress, including gene expression and miR regulation.3. Using iPSC-derived myocytes to understand heart failure and congenital heart disease.4. Tools for evaluation of cardiac physiology in transgenic mice and isolated cardiomyocytes.5. Anti-body mediated rejection.6. Biomarkers for post-transplant lymphoproliferative disorder.

Current Research and Scholarly Interests
My interests include the genetics of autism and other developmental disorders. In collaboration with colleagues at Stanford, I am working to develop induced pluripotent stem cell (iPSC) models of genetic disorders associated with developmental disability. I am also engaged in the application of new technologies (Whole genome sequencing, Multi-omics profiling) for the diagnosis of developmental disorders.

Bio
Dr. Berry joined the Division of Thoracic Surgery at Stanford in August 2014. He came to Stanford from Duke University, where he had most recently served as Associate Professor. He received his medical degree at the University of Pennsylvania School of Medicine after receiving bachelors and masters degrees in Electrical Engineering at the University of Pennsylvania. He completed his residency in Cardiothoracic Surgery at Duke University Medical Center after performing a residency in General Surgery at the Hospital of the University of Pennsylvania. His Cardiothoracic Surgical training included a year dedicated to Minimally Invasive General Thoracic Surgery, a period that also included an American Association for Thoracic Surgery sponsored Traveling Fellowship at the University of Pittsburgh.

Dr. Berry practices all aspects of thoracic surgery, including procedures for benign and malignant conditions of the lung, esophagus, and mediastinum. He has a particular interest in minimally invasive techniques, and has extensive experience in treating thoracic surgical conditions using video-assisted thoracoscopic surgical (VATS), laparoscopic, robotic, endoscopic, and bronchoscopic approaches. He serves as the co-Director of the Stanford Minimally Invasive Thoracic Surgery Center (SMITS), and has both directed and taught in several minimally invasive thoracic surgery courses.

Dr. Berry also has a Masters of Health Sciences in Clinical Research from Duke University. His clinical research activities mirror his clinical interests and activities in optimizing short-term and long-term outcomes of patients with thoracic surgical conditions. He has more than sixty peer-reviewed publications, most of which are related to both the use of minimally invasive thoracic surgical techniques as well as evaluating outcomes after treatment of thoracic malignancies. His clinical practice and his research both focus on choosing the most appropriate treatment and approach for patients based on the individual characteristics of the patient and their disease process.

Current Research and Scholarly Interests
Dr. Bhalla's research interests are in the pathogenesis of diabetic kidney disease and salt-sensitive hypertension. Using molecular and transgenic approaches, the laboratory is interested in elucidating regulators of oxidative and carbonyl stress in glomeruli. We interface these studies with collaborative projects on biomarkers for human diabetic nephropathy.

The laboratory also focuses on molecular mechanisms of insulin and aldosterone-induced sodium transport in the distal nephron.

Current Research and Scholarly Interests
The Bhatt lab is exploring how the microbiome is intertwined with states of health and disease. We apply the most modern genetic tools in an effort to deconvolute the mechanism of human diseases.

Current Research and Scholarly Interests
My research focuses on the constraints that vulnerable populations face in making decisions that affect their health status, as well as the effects of government policies and programs designed to benefit vulnerable populations.

Current Research and Scholarly Interests
The long-term goal of our research is to understand the fundamental mechanisms that govern and reprogram cellular fate during development, regeneration and disease.

Current Research and Scholarly Interests
Dr. Bishop specializes in treating fractures of the upper extremity, lower extremity, pelvis and acetabulum as well as the management of post-traumatic problems including malunion, nonunion and infection.

He received his undergraduate and medical school degrees from Harvard University and went on to complete the Harvard Combined Orthopaedic Surgery Residency Program. He pursued his subspecialty training in Orthopaedic Traumatology at the world-renowned Harborview Medical Center in Seattle, Washington.

His research interests include applying decision analysis models to orthopaedic trauma problems, studying clinical outcomes after musculoskeletal injury, orthopaedic biomechanics, the basic science of fracture healing, and evaluating new strategies and techniques in fracture surgery.

Current Research and Scholarly Interests
Chronic pain sufferers are unfortunately limited by poor diagnostic tests and therapies. Our lab is interested in 'imaging pain' by using multimodality molecular imaging techniques to study nociception and neuronal inflammation as a means of improving objective, image-guided diagnosis and treatment of chronic pain disorders. We develop new molecular contrast agents for use in positron emission tomography (PET) and magnetic resonance imaging (MRI), working towards eventual clincal translation.