Abstract

The reaction of 5-amino-2-mercaptobenzooxazole with tetramethylthiuram disulfide affordedN,N-dimethylthioureido-2-mercaptobenzooxazole, which was converted into 5-isothiocyanato-2-mercaptobenzooxazole under the action of AcCl, Ac2O, or HCl. Based on the latter compound, 4-(2-mercaptobenzooxazol-5-yl)thiosemicarbazide was synthesized, whose reactions with aldehydes and ketones yielded the corresponding thiosemicarbazones.