A facial abrasion wound
A 16-year-old man fell while riding his bicycle and he presented to our hospital. At the examination, he had abrasion with bleeding on his left cheek and chin. With hydrocolloid dressings for three days, epithelialization is completed. Ten days following the injury, the wound is healed without scarring.

A 4-year-old boy fell down and hit his forehead against the edge of a piece of furniture. The right forehead laceration reached the layer of the periosteum. We closed the wound with plaster to stop the bleeding by pressing. applying the layer of the rolled gauze shed further pressure . The following day, Steristrips with compression were applied. Days 3, the wound is closed without hematoma. We gave instructions to family members about further management of the wound at home.

Around day 8, he presented with pyrexia of 37.8°C and mild wound pain, for which intravenous drip infusion of Cefamezin was administered. Pyrexia and wound pain improved after 1-time intravenous drip infusion.

Almost the entire surface on the volarl and dorsal sides showed epithelization; however, epithelization on the ulnar forearm was delayed. On day 30, the burn was considered as third degree, but Plusmoist(TM) was continuously applied.

On day 48, insular epithelization was observed even on the lesion that was considered a third-degree burn. All lesions had healed on day 55, and no contracted scar was observed.

primary condition:dorsal side of forearm

after removval of blister

6 days later

11 days later

15 days later

28 days later

33 days later

48 days later:small white spots are epithelization from hair folicles of dermis

55 days later:no cicatrical contracture

The skin ulcer on the ulnar surface examined on day 30 might have been diagnosed as a third-degree burn by some physicians who would have considered skin grafting. However, when the image of the same lesion was examined on day 48, it was observed that the wound was not a third-degree burn. This was because the white spots that had developed in the center of the wound were regenerated skin with dermal appendages, including deep follicles resurrected from the lesion. Thus, the wound was not a third-degree burn, but a second-degree burn.

Burns of such depth take usually 40 to 50 days after the injury to regenerate epidermis from the dermal appendage, because it takes a long time for the dermal appendage to regenerate from the damage caused by the initial heat. Thus, until 40 days after injury, it is unknown whether the wound is a third-degree burn or not, and an accurate diagnosis cannot be made.

Accordingly, except in cases in which the skin shows a parchment-like appearance within a few days after the first visit, the diagnosis of a third-degree burn has to be made 40 to 50 days after the injury. In addition, the necessity of a skin graft has to be evaluated after that period. However, when we examine the condition of this patient on day 30, we should conclude that the diagnosis of "this wound is a third-degree burn that cannot be cured exclusively by skin grafting" would be wrong, and thus, skin grafting would be an unnecessary treatment.

In addition, this case also tells us that "the source of infection of the burn wound is the remaining blister fluid (blister membrane)." Blister fluid is usually sterile but becomes a nutritious bacterial medium and a source of infection when even a part of the membrane is broken. Therefore, the blister membrane or the future source of infection has to be removed as much as possible at the first visit in order to prevent an infection.

Moreover, antibiotic administration to prevent an infection is meaningless if the partly broken blister membrane remains in the wound. Of course, the symptoms of cellulitis would temporarily subside, but cellulitis would eventually exacerbate if infected blister fluid of large amounts of bacterial medium remain in the wound.

Furthermore, Plus Moist with white petrolatum (lightly applied) was administered at the first visit, but white petrolatum was only required for the first treatment and not thereafter. White petrolatum was applied for the first treatment in an attempt to halt contact with air as much as possible, and it was not required after the second treatment because effusions adequately covered the wound surface.

A-two-years-old boy was burned his right foot by hot water. His parents brought him to a plastic surgery of a nearby general hospital. He was treated with silver-sulfadiazine cream and gauze dressing.

Two weeks after the injury, his doctor informed the parents as "Skin graft is indispensable for healing. Gait problem is unavoidable without early skin graft. Sepsis is inevitable without surgery." However, the parents could not agree to the opinion. Afterward the parents got information about moist wound healing via the internet and brought him to our hospital.

A 60 year-old-woman sustained burns of her face and neck at her home. The stove in the kitchen had ignited her scarf. She was on dialysis. She was diabetic and had self-injection of insulin. The burn day, she went the dialysis center and received primary burn care.
She was suffered from severe diabetes and diabetic renal insufficiency, and was treated hemodialysis at the dialysis center for 5 years.
Day 3, she admitted to the dialysis devision of our hospital and we were consulted about the burn wounds.

At our first evaluation, she had burns of forhead, eyelids, cheeks, left ear and neck. The right half of forehead burn was partial thickness. The burns of left half of forehead ranged from left upper eyelid to part
of the head. It was extensive and quite deep impression.
We debrided the blisters and loose skin. The burn from forehead to neck was sealed with Plusmoist(TM). The lesions of bilateral eyelids and cheek was covered with Duoactive(TM).

Day 6, the burn of her right cheek was re-epithelialized. Left cheek burn came to full-thickness necrosis. The necrotic tissue of forehead was quite thick. We evaluated that it was third degree burn. Left upper eyelid lesion was re-epithelialized within one week.

Day 17, She was discharged. As the outpatient, she came to our wound center twice a week. We educated her various methods, that she did at home. They included several dressings (eg. Plusmoist(TM)), direct sealing with wrap and others. She tried every methods and choiced the most comfortable one for herself. Necrotic tissue was liquefied by autolysis. We excised floating parts of necrotic tissue.

Day 59, most of forehead lesions ranging from left eyeblow to hairline were re-epithelialized. She covered the surface of granulation with food package wrap. Wearing scarf over it, she lived at home without problems. As the exudate form burn was not much, she never mind it and did not care about it.

Day 72, the ulcer on the front side of the left auricle was re-epithelialized. the large ulcer spreading from left eyeblow to the lateral canthus was seen.

Day 113, all lesions were completely re-epithelialized. Very mild scar contractures were seen.
Day 164, we had last follow-up on her. She had no visible scar and pigmentation on her forehead. Compared with her right eyeblow, her left one was lifted a little. Opening and closing eyes were normally performed. She did not have complaints that difficulty in closing eyes and feeling dry eye.

The patient is a 60 years old male worker; suffering from the cut wound of dorsal side of the left thumb visited our hospita. The wound was diagnosed as the defect of the nail plate and nail bed, complicated with the open bone fracture of the distal phalanx.

I attached the sodium alginate dressing. At the initial diagnosis, I removed the blood coagulation, attached the sodium alginate dressing on the wound and enclosed the wound by the film.

The day after the first visit, his nail bed was embedded by the surrounding healing granulation. I altered the dressing from sodium alginate dressing to Plusmoist(TM).

the first condition

covered with alginate dressing

one day after

11 days after

21 days after

He chanced to re-visit our hospital on 94 days after, and I confirmed the complete reconstitution of the left thumb nail. The nail plate of his left thumb fully covered the nail bed, and fully recovered the intact nail form.

Next day, irrigation and application of Plusmoist(TM). The patient had almost no pain when the lesion was washed.
Six days later, the wound surface was covered by clean granulation tissue, but the size of the wound remained unchanged. There was nothing particularly noted during the clinical course. She had no pain during exercise and was able to perform her daily housework.

Although 49 days had passed, the wound had not reduced in size to a great extent; only the wound on the distal back side was slightly smaller. However, she had no pain during exercise and was able to perform her daily chores.

About 2 months after the incident, the width of the wound had shrunk, but the length of the wound had not changed to a great extent. The width of the wound was little larger than 1 cm at 83 days after the incident.

Only a shallow ulcer remained in the center of the wound at 97 days after the incident, and the entire wound had epithelized at 104 days after the incident. Follow-up was performed until 139 days after the incident. Only a mild scar remained. No contracted scar was observed, and she experienced no differences in the movements of the forearms as well as the wrists. In addition, she had no feeling of stiffness.
Now, you might have a different view with regard to the treatment of this case, for example:

primary condition

6 days later

21 days later

49 days later

76 days later

83 days laterr

97 days laterr

104 days laterr

139 days laterrno cicatrical contracture

Why did not they perform a skin graft? It is strange for a plastic surgeon because the wound would have healed if skin grafting had been performed.

Internists and psychiatrists can treat wounds of such sizes because they heal without skin grafting and result in no impairment.

It is good that patients do not have to undergo surgery or need to be hospitalized, but it takes 3 months to recover completely.

This is better because although 3 months are required for complete recovery, no surgery or hospitalization is required, and the patient can work as usual.

The following aspects of the issue have to be excluded: the physician's convenience and thephysician's imposition of good will. Physicians tend to consider that "rapid treatment and accelerating wound healing are good." However, they are not necessarily "good" for patients.

For instance, it would not be the best outcome for the patient if his/her body movement is limited and a dysmorphic disorder remains as a result of accelerated wound healing. Although the time the physician spends with the patient is limited, the patient has to use his/her body for the rest of his/her life. In other words, the time required by the physician for determining the result of the treatment is completely different from that for patients.

Surgery is necessary to treat wounds rapidly, but if some impairment remains for the rest of the patients' lives (even if it is a mild impairment), such a treatment is considered a failure. Grafted skin definitely causes a contracted scar. If it is inevitable, skin grafting is the worst treatment for patients.

Thus, it is wrong to perform a therapeutic evaluation on the basis of thephysician's logic. For example, even if a chef cooks using a great technique, he fails if the dish tastes bad. Thus, there is a bias if the person who cooks the dish is not different from the person who assesses it.

However, in the medical sciences, physicians perform both therapeutic evaluation and surgery. The problem lies in the fact that no one is concerned about this abnormality.

First, the following data was revealed in this case:

The patient went about her daily life a few days after the injury, although the lesion was at the ulnar surface of the distal forearm that moves, hits things, and becomes compressed frequently in daily life.

It is a fact that "granulation tissue decreases in size because of the effect of myofibroblasts." However, contraction of granulation tissue in this patient did not occur in the direction of the long axis (the direction of movement) but progressed only in the direction of the horizontal axis, which does not move.

(Possibly) as a result of the abovementioned clinical course, no contracted scar or movement disorders were observed.

The wound healed and a scar was formed. However, the size of the scar was far smaller than that of the initial wound (diameter, 9 cm), and it was undistinguishable. In addition, the patient showed no sequelae attributable to the scar or symptoms. Thus, this scar was different from the scar formed after skin grafting in terms of quality as well as quantity.

In other words, it took several months for complete epithelization, but the scar was undistinguishable and no movement disorder developed; this allowed the patient to perform normal daily activities and work during the treatment period. In fact, I have the impression that the body adjusts to the duration of epithelization in order to suppress wound contraction, which causes movement disorder.

The same phenomenon as that in the case of "wide range of third-degree burn wounds on the forehead," which I had reported in the past, can be considered here. It took several months for complete epithelization; however, as a result, the patient showed no limitation of eyelid movement or sequelae.

With respect to these cases, the time lags from covering of the wound surface with granulation tissue to the onset of wound contraction is considered to be the required duration for the granulation tissue to obtain the mobility required for the region. Moreover, it is considered that the body is ¡Èwaiting¡É for the best time to achieve the required mobility in regions that take time to epithelize.

Thus, I believe that epithelization does not take a long time, but the body "waits" for a condition in which it requires the shortest time to regenerate granulation tissue and dermis, according to the amount of physical activity in this region.

Given this perspective, it is possible to explain why contracture occurs after skin grafting: When skin grafting is performed at an early stage, the granulation tissue of the graft bed is immature and has not yet had the required amount of physical activity in this region. It is considered that movement disorders are caused by a skin graft that covers all the granulation tissue in such conditions.

Therefore, for wound epithelization without movement disorders, it is first necessary to generate granulation tissue (= the base of the regenerating epithelium) that responds to the requirement that no movement disorder develops. Second, it is necessary to regenerate flexible skin on the base. It is considered that it takes a long time to achieve it. Skin grafts ¡Èsteal¡É the time required for it.

Why is skin grafting the worst treatment? Because skin grafts tentatively cover the wound without "waiting" for regeneration of the tissue (= granulation tissue) required to allow physical activities; this causes skin contracture and results in movement disorders of the contracted scar. When a skin graft is performed, "the wound will heal quickly but contracture will develop later." However, this is a natural phenomenon.

In addition, healthy skin has to be collected for skin grafting; this means that healthy parts of the skin have to be peeled and grafted.

At this point, majority of the plastic surgeons consider that ¡Èthere is no problem because the skin is collected from a region that cannot be seen,¡É but this is wrong as they only think about their convenience. They do not consider the patient who will have scars in an uninjured region.

Patients would have a scar in a region that did not get burned, but the physicians would not have any scars. Physicians do not feel any pain when they cause "new scars." Thus, they persuade patients, stating that "there is no problem in collecting the skin because the region cannot be seen." They do not know how much pain the patient experiences in order for them to be able to perform a skin graft.

Curing a wound at an early stage and having the patient discharged promptly is not necessarily "good" for the patients. As far as skin grafting is concerned, I have no doubt that curing a wound at an early stage by using skin grafting results in the worst result.

I am expecting objections and counterarguments from plastic surgeons and dermatologists who prefer to perform skin grafting.