Frequently asked questions for Nisul Plus 100 mg/50 mg Capsule

Frequently asked questions for Diclofenac

Q. What is the difference between Diclofenac and naproxen?

In research studies, naproxen has been found to have lesser cardiovascular events like stroke and heart attack than Diclofenac. Another key variations naproxen may be more likely to be recommended for the treatment of inflammatory conditions in young patients as compared to Diclofenac.

Q. What is the difference between Diclofenac and ketoprofen?

Although both these agents are non-steroidal anti-inflammatory drugs (NSAIDs), there is a subtle difference in the way they act. Ketoprofen blocks the Cyclo-oxygenase (COX) enzyme without any preference for blocking of any one of this enzyme subtypes. Diclofenac has the preference to block COX-2 subtype of Cyclooxygenase enzyme. Blocking of COX reduces prostaglandins (chemicals naturally produced by the body that is responsible for pain and inflammation).

Q. Can Diclofenac be used along with warfarin?

No. Using Diclofenac together with warfarin can increase the risk of serious bleeding from the stomach (Higher than users of either drug alone). Inform your doctor before starting these medications.

Q. Are Diclofenac and ibuprofen same?

No. Diclofenac and Ibuprofen are different medicines but they both belong to the same class of drugs i.e. Non-Steroidal Anti-inflammatory Drugs (NSAIDs). Both are commonly used as painkillers.

Q. Is Diclofenac a painkiller?

Yes. Diclofenac is a pain killer. In fact, it belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis and spondylitis.

Q. Is Diclofenac a narcotic?

No, Diclofenac is not a narcotic. Narcotics are drugs with sleep inducing properties, usual derivatives of Opium like Heroin and Morphine.

Q. Can I use Diclofenac along with vitamins?

Yes, Diclofenac can be taken with vitamins. No drug-drug interactions or any harmful effects have been reported when they are used together.

Q. Can Diclofenac be used for the treatment of hepatitis?

No, Diclofenac is not approved for the treatment of hepatitis. Hepatitis is a condition where the liver is inflamed. Diclofenac can, in fact, cause harm to the liver as a side effect.

Q. Can Diclofenac be used after C-section?

Yes, Diclofenac is a pain killer. C-section is the short name for Cesarean Section which is an operative procedure to deliver the baby through the mother's abdomen and uterus. Diclofenac can be used to treat the pain that may occur after the operation.

Q. What is the difference between Diclofenac and baclofen?

Diclofenac is a pain killer. It belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis and spondylitis. Baclofen is a depressant of the nervous system, used to relax the muscles and also used in to reduce pain. Baclofen is used for the treatment of spinal cord injury, cerebral palsy, and multiple sclerosis.

Q. What is the difference between Diclofenac and lidocaine?

Diclofenac is a pain killer. It belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis and spondylitis. Lidocaine (also known as xylocaine and lignocaine) is a medication primarily used to numb tissue in a specific area before any surgical procedure and is also used to treat ventricular tachycardia (a condition where the beating rhythm of the heart gets disturbed.

Q. Which is the best choice between Diclofenac and aceclofenac?

The researcher has proved that aceclofenac is a better alternative to Diclofenac with fewer side effects, especially in the treatment of osteoarthritis, ankylosing spondylitis. Both Aceclofenac and Diclofenac are NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) and used as painkillers.

Q. Which is the best choice between Diclofenac and ibuprofen for back pain?

Both Diclofenac and Ibuprofen can be used for back pain. Currently, there are not many studies which can identify the best treatment between the these two agents.

Q. Which is the best choice between Diclofenac and ibuprofen for a toothache?

Both Diclofenac and Ibuprofen can be used for toothache. Currently, there are not many studies which can identify the best treatment between the these two agents. However according to one study, a combination of Diclofenac with paracetamol has been found to be better then a combination of Ibuprofen and paracetamol.

Q. What is the difference between Diclofenac and meloxicam?

Meloxicam has been found to have fewer gastrointestinal side effects than Diclofenac and its use is associated with an increased risk of cardiovascular events such as heart attack and stroke.

Q. Can I take Diclofenac along with misoprostol?

Yes. It can be taken together. Misoprostol protects the stomach from irritating gastric effects of Diclofenac. The combination of medication is used to treat arthritis in patients at high risk of getting stomach/intestinal ulcers and complications from the ulcers (such as bleeding).

Q. Can I take Diclofenac while I am on thyroxine?

Yes, Diclofenac can be taken with thyroxine. No drug-drug interactions or any harmful effects have been reported when they are used together.

Q. Why Diclofenac should be stopped before surgery?

Since Diclofenac has been shown to have blood thinning effects, it can increase the risk of bleeding. Therefore, it is stopped before surgery to prevent excessive loss of blood.

Q. What are the contraindications for Diclofenac?

Diclofenac should not be used if there is an allergic reaction (hypersensitivity) to it, or other pain killers, active ulcer in the stomach, bleeding from the stomach, history of severe heart failure, liver failure, kidney failure and or heart attack.

Q. Can Diclofenac affect the chance of conceiving?

Yes. Diclofenac can sometime cause reversible infertility. Diclofenac by its mechanism of action, may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

Q. Why does Diclofenac cause an ulcer?

Diclofenac can cause damage to the lining cells of the stomach by several mechanisms, including the irritant effect on the cells, breaking of the protective barrier properties of lining cells, suppression of prostaglandin production of the stomach, reduction of stomach mucosal blood flow and interference with the repair of superficial injury of the stomach lining.

Q. Why is Diclofenac contraindicated in asthma?

Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory drugs (NSAID) like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Q. Is Diclofenac good for back pain?

Yes, Diclofenac has been found to be effective to reduce back pain. Diclofenac is a pain killer that belongs to the NSAIDs (Non-Steroidal Anti-Inflammatory) class. Other NSAIDs have also been found to be useful in back pain eg. Ibuprofen and Naproxen.

Q. Can I use Diclofenac during my fever treatment?

Yes, Diclofenac can reduce fever. However, commonly used to reduce the pain, particularly that which is seen with Osteoarthritis, Rheumatoid Arthritis and Ankylosing spondylitis.

Q. Can I use Diclofenac to treat a sore throat?

Sore throat is mostly caused by bacteria so antibiotics are given to treat a sore throat whereas Diclofenac is a pain killer so it can be given in cases of throat pain associated with it but only under the prescription of a doctor.

Q. Can I use Diclofenac to treat urinary tract infections (UTI)?

Diclofenac can be used to treat the pain associated with urinary tract infection (UTI) but for complete treatment, a course of antibiotics will be required.

Q. Can Diclofenac cause sedation?

Diclofenac is not known to cause sedation. There have been rare, an isolated case report of sedation with the drug.

Q. Can I take Diclofenac for kidney stones?

Yes,Diclofenac can be used to relieve the pain due to kidney stones. However, there is also a risk of kidney damage with Diclofenac as its side effect. It is advised not to take Diclofenac for a prolonged time for this condition without adequate monitoring.

Q. Can I use Diclofenac for the treatment of arthritis?

Yes, Diclofenac is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis, and spondylitis.It belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). .

Q. Can I use Diclofenac with diuretics?

No, Diclofenac should not be used with diuretics. Diclofenac reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.

Q. Can I use Diclofenac with mifepristone?

These drugs should not be used together as the effect of mifepristone may be lowered by Diclofenac. Mifepristone is used for medical abortion.

Q. Can I use Diclofenac with lithium?

No.These drugs should not be used together as Diclofenac increases the blood levels of lithium which may further increase the side effects.

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Frequently asked questions for Nimesulide

Q. Is Nimesulide an antibiotic?

Nimesulide is not an antibiotic, it belongs to the class of medicines known as non-steroidal anti-inflammatory drug (NSAIDs; pain-relieving drug) which helps in relieving pain associated with various disease conditions.

Q. Can I take Nimesulide with paracetamol?

Nimesulide and paracetamol belong to the same class of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs; pain-relieving drugs). Taking the two medicines together is not advisable as it may increase the potential for gastric ulceration and bleeding. However, please consult your doctor before using the two medicines together.

Q. Does Nimesulide contain aspirin?

Nimesulide is a non-steroidal anti-inflammatory drug (NSAIDs; pain-relieving drug). It does not contain aspirin.

Q. Is Nimesulide safe?

Nimesulide is safe to use if taken at prescribed dose and duration as advised by your doctor.

Q. Can I take Nimesulide for headache?

Nimesulide can be taken for a headache only when advised by your doctor.

Q. Does Nimesulide make you drowsy (feeling sleepy)?

Nimesulide does not make you feel drowsy at prescribed doses. However, an overdose of Nimesulide can make you drowsy (feeling sleepy).

Q. Does Nimesulide contain sulphur?

No, Nimesulide does not contain sulphur.

Q. What does Nimesulide treat or used for?

Nimesulide is used to treat acute pain, painful osteoarthritis (degeneration of joints) and primary dysmenorrhea (painful menstruation) in adolescents and adults above 12 years old.

Q. Can I take Nimesulide with ibuprofen?

Nimesulide can be taken with ibuprofen. No drug-drug interactions have been reported between the two. However, taking the two medicines together is not advisable as it may increase the potential for gastric ulceration and bleeding. Please consult your doctor before taking the two medicines together.<br>

Q. Can I take Nimesulide with aspirin?

Nimesulide can be taken with aspirin. No drug-drug interactions have been clinically observed between the two. However, this does not mean that interactions cannot occur. Please consult your doctor before taking the two medicines together.

Q. Is Nimesulide safe?

Yes, Nimesulide is safe if taken for prescribed duration in prescribed doses as advised by your doctor.

Q. Is Nimesulide banned?

No, Nimesulide is not banned in India.

Q. Is Nimesulide safe during breastfeeding?

It is not known if Nimesulide is secreted in milk. So, any medicines containing Nimesulide are not to be used during breastfeeding.

Q. Is Nimesulide safe in pregnancy?

No, Nimesulide is not safe to be used in pregnancy especially in the last three months. There have been reports of kidney failure in newborn babies if the mother was taking Nimesulide in the late stage of pregnancy. Consult your doctor before taking any medicine during pregnancy.

Q. Is Nimesulide safe in asthma?

Nimesulide is reported to be safe in patients with asthma if taken as advised by your doctor. However, always share your disease history with the doctor in case you have asthma and you are advised to take other medicines.