Set in Springfield, the average American town, the show focuses on the antics and everyday adventures of the Simpson family; Homer, Marge, Bart, Lisa and Maggie, as well as a virtual cast of thousands. Since the beginning, the series has been a pop culture icon, attracting hundreds of celebrities to guest star. The show has also made name for itself in its fearless satirical take on politics, media and American life in general.

When Homer and Marge are found to be unfit parents, the kids are placed with the Flanders family. Reluctant participants in the Flanderses' wholesome family activities, Bart and Lisa become the targets of an emergency baptism.

In "Attack of the 50 Foot Eyesores," strange atmospheric conditions bring giant advertising statues to life. In "Nightmare on Evergreen Terrace," Groundskeeper Willie is killed in a freak accident and seeks revenge in the childrens' dreams. In the final segment, Homer steps through a secret portal and becomes three-dimensional.

Troy McClure hosts a behind-the-scenes look at the show, including clips of the series' beginnings as filler on "The Tracy Ullman Show," Simpsons trivia questions, and unaired scenes from popular episodes.

Homer catches Mr. Burns in an ether-induced haze and asks for $500 for his bowling team. When Burns' head clears, he demands to join the team. Meanwhile, Bart's inflammatory T-shirt provokes Principal Skinner to require school uniforms.

In a scheme to get Krusty's autograph, Bart sends him a check. When Krusty's offshore holding corporation endorses the check, his illegal tax shelter is exposed. In despair after the government auctions off his possessions, Krusty fakes his own death.

Bart creates a fake driver's license for himself and uses it to go on a spring break road trip with Milhouse, Nelson, and Martin. Meanwhile, Homer and Lisa bond after spending some quality time together at work.