Patient-Reported Outcomes Measurement (CEPI5308)

UNIT OF STUDY

The aim of this unit is to enable students to appraise patient-reported outcome measures (PROM) and incorporate them into clinical research. PROMs include: symptoms, side-effects, health-related quality of life, satisfaction and preferences. Topics include: definitions, structure and functions of PROMs; item-generation and selection; questionnaire design; assessing validity, reliability and responsiveness to clinically important change; utilities and preferences; developing and appraising studies using PROMs. The online sessions comprise six lectures outlining the principles, with illustrative examples (approx 90 minutes per lecture), plus a series of 5 related quizzes (approx 30 minutes). The written assignment may be one of four options (student's choice): 1) a protocol for the development and validation of a new PROM; 2) a protocol for the revalidation of an existing PROM in a population in which it has not previously been validated; 3) a protocol for application of an existing PROM for a specific purpose in a specific patient population and clinical context; 4) an appraisal of the application of an existing PROM as an outcome in a clinical study.

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