OBJECTIVE
The present study was performed to investigate the possible association of -590 C/T polymorphism in the interleukin-4 (IL-4) gene which affects its expression with the risk for development of oral cancer.
STUDY DESIGN
Polymerase chain reaction-based restriction analysis was performed in DNA samples of 156 patients with oral squamous cell carcinoma (OSCC) and 162 healthy control subjects of equivalent gender, age, and ethnicity (Greek and German). Statistical analyses were performed… CONTINUE READING