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The Americans went an undefeated 8–0 and averaged 116 points per game, winning by an average margin of 32.1 points—the fifth highest in US Olympic history. Team USA trailed in the fourth quarter only once, against Lithuania in the opening round. James became the leader of the team with Bryant—who would turn 34 in August 2012—stepping back. James facilitated the offense from the post and perimeter, called the defensive sets, and provided scoring when needed. After winning the gold, Team USA coach Mike Krzyzewski said James "is the best player, he is the best leader and he is as smart as anybody playing the game right now." Durant scored a United States Olympics record of 156 points in the tournament. He also made 34 three-point field goals, breaking the previous United States mark of 17; Anthony (23) also exceed the old record. Bryant was not in peak condition early, but he played himself into shape and was a key contributor in the final three games. While Chandler was the team's only true center—Davis was thin and had no professional experience—Krzyzewski also played Love, James or Anthony as Team USA's de facto center. Love led the team with 61 rebounds (27 offensive).

Compensating for its lack of big men, the US played small ball and spread its playmakers around the three-point line and with a player penetrating and passing the ball back outside. They won with "basically five players on the perimeter," Spain coach Sergio Scariolo said. Bryant and Krzyzewski declared at the completion of the tournament that 2012 was their final Olympic appearance. They both joined Team USA after the disappointing bronze finish in the 2004 Games. Krzyzewski left with a 62–1 record and a 50-game winning streak in international play for the Americans. He joined Henry Iba as the only US coaches to lead the team to consecutive Olympic gold medals. In 2013, Team USA announced Krzyzewski would return as head coach from 2013 through 2016.