Turner-Webster started her career at Signal Radio, writing, producing and presenting on-air features including film, travel and book reviews.[1] She also wrote for magazines including OK!. A part-time actress, while appearing in the pantomimeCinderella, she was spotted by a producer from the UK cable channel L!VE TV.[1] Moving to London, she became a news reporter covering sports and fashion. She then hosted her own shows Videobox and the psychic phone-in Revelations with Nina.

Turner-Webster was chosen to take over hosting Channel 4’s Absolutely Animals from Dani Behr;[1] the show was a forerunner to Pet Rescue which Turner-Webster hosted for 7 years.[1] Turner-Webster's other TV projects include BBC One's Your Kids Are In Charge, presented with sister Anthea. She has also presented several episodes of The Last Word for Central Television, and the BBC documentary about domestic violence, Hitting Home.

Turner-Webster does not eat or wear animal products and is Patron of the Vegan Society, Viva! and the Vegetarian Society.[1] In 2001, Turner-Webster wrote on behalf of PETA to the Duke of Kent as president of the Scout Association, requesting that they retire the angling badge on grounds of cruelty to animals. The proposal was rejected.[2] In 2006, she launched an on-line footwear company, "Secret Goddess", which specialised in ultra glamorous boots and shoes of non-animal origin.

In November 2010, Wendy became the patron of Chancepixies Animal Rescue, a charity dedicated to educating, rescuing and taking action to prevent dogs in the UK from finding themselves unwanted, abused and killed.[3][4][5]