Ball powder is more sensitive to temperature. That doesn't mean, however, that you need to develop a load for every 5 degrees of temperature variation though.

If you are shooting long distances over a wide variation of temperatures (think something like from -10 as the low extreme up to 100+ as the high extreme), then you would probably need to assess the different characteristics for low, medium and high temperatures. Outside of that though, it's really not something you are going to notice.

Military powder is WC844 and WC846 for 5.56 and 7.62, both of which are ball powders - and they manage to work just fine from the hot deserts of Iraq all the way up to the higher elevations in the Hindu Kush.