Glioblastoma (GBM) is a highly aggressive
brain tumour, where patients respond poorly to radiotherapy
and exhibit dismal survival outcomes. The mechanisms
of radioresistance are not completely understood. However,
cancer ...

Dietary intake of linoleic acid (LNA, 18:2n-6) has increased dramatically during the 20th century and is associated with greater prevalence of obesity. The endocannabinoid system is involved in regulation of energy balance ...

<p>Background: Tunneling nanotubes (TNTs) may offer a very specific and effective way of intercellular communication. Here we investigated TNTs in the human retinal pigment epithelial (RPE) cell line ARPE-19. Morphology ...

Despite the well-documented cooperation between neurons and astrocytes little is known as to how these interactions are initiated. We show here by differential interference contrast microscopy that immature hippocampal ...

The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major chemoattractant for monocytes, involved in an array of chronic inflammatory ...

Background: Hypoxia is associated with increased resistance to chemo- and radiation-therapy.
Hyperoxic treatment (hyperbaric oxygen) has previously been shown to potentiate the effect of
some forms of chemotherapy, and ...

<p>Glioblastoma (GBM) is the most frequent and aggressive brain tumor in adults. The patients’
median survival is only 14.6 months despite multimodal treatment, including surgery and
concomitant radiation and chemotherapy. ...

The family of the aromatic amino acid hydroxylases (AAAH) is well studied in
mammals. It includes four members, i.e. phenylalanine hydroxylase (PAH), tyrosine
hydroxylase (TH) and the tryptophan hydroxylases (TPH1 and ...