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Britain's youth have taken to Twitter to share their regret at the decision to leave the European Union using the hashtag #notmyvote.

The 52 to 48 per cent decision in favour of leaving the EU defied pollsters, bookies and market expectations on Friday, forcing Prime Minister David Cameron to resign and financial markets to shed billions of dollars.

It's also led to huge question marks over issues like visa-free travel in the eurozone, passports, house prices and reciprocal healthcare that could take months to work out.

Voting results showed the country deeply divided with 16.1 million people mainly in London, Scotland and Northern Ireland voting in favour of Remain. Meanwhile 17.4 million others throughout the rest of the country voted in favour of Leave with a total turnout of more than 70 per cent.

Young people took to Twitter to share their displeasure with some calling for a second referendum and crashing the government petition website to demand one. Others chided them for not accepting the result on the day.

Chatham House Director, Dr Robin Niblett said the challenge now for the Leave campaign is to address the "yawning gap" that could emerge between rhetoric and the reality of life outside the European Union.

"This will not be easy. Blaming the EU for all of Britain's ills has been pure displacement activity. Contrary to some of the rhetoric, the EU has not hogtied the UK in regulation and has not drained funds from the Exchequer," he said.

the most annoying this is that I'm 18 in less than 4 months and old people are deciding my future #notmyvote

Brexodus begins?

Brits are now grappling with a series of questions over how the new political landscape will affect them.

While leaders have been at pains to stress nothing will change in the short term, reports have already emerged of job losses and price rises that could affect life for millions of people.

Banking giant Morgan Stanley denied it will move 2000 staff out of London offices to Dublin or Frankfurt. It follows warnings from JP Morgan and Morgan Stanley that up to 10,000 jobs could be shifted to the EU in the event of a Brexit.

On Friday, Australia's Commonwealth Bank suspended its currency trading services for those wanting to exchange dollars into pounds trigging outrage from many online who could not access their cash.

There are also huge questions about what it could mean for travel, holiday prices and passports.

At present UK passport holders have access to 175 countries with a visa-on-arrival service. Nearly 1.3 million Brits living in Europe could also face changes after the pound fell to its lowest level in 30 years.

The UK government has already warned citizens who enjoy reciprocal healthcare and other rights abroad they "would not be able to assume that these rights will be guaranteed" in the event of a Brexit.

Irish voters struggled to come to terms with the fact land borders could go back up between Northern Ireland and the Republic of Ireland.

'How to get an Irish passport?' was one of the most Googled questions in the UK following the results.