Level of Evidence B: Data derived from a single randomized trial or nonrandomized studies

Level of Evidence C: Consensus opinion of experts

UHMS Guidelines for Adjunctive Therapy of DCI

Aspirin

Class

Level

AGE (no significant inert gas load)

2B

C

DCS: pain only/mild

2B

C

DCS: neurological

2B

C

DCS: chokes

2B

C

NSAIDs*

Class

Level

AGE (no significant inert gas load)

2B

C

DCS: pain only/mild

2B

B

DCS: neurological

2B

B

DCS: chokes

2B

C

* The only evidence thus far available applies to the use of tenoxicam, a nonselective inhibitor of cyclooxygenase (COX). NSAIDs are not currently recommended for use in the field. Use of nonselective COX inhibitors, because of their effect on platelet function, could engender some risk for combat divers who may be required to return to action after treatment of an episode of decompression illness.

Disclosure: The views, opinions, and findings contained herein are those of the author(s) and should not be construed as an official Agency position, policy, or decision unless so designated by other official documentation.