I'd like to walk using only my mouse, as I can do in other games like Diablo 3. I searched and didn't find an option for this in Guild Wars 2. Is there no option to do this? Is there a workaround? A left hand handicap makes "W_S_A_D" or arrow keys difficult for directing my avatar.

Are all your questions going to be essentially "can I click-to-move in [Insert Game Name Here]"? While I understand it can be useful, especially for those with disabilities, a lot of games just aren't designed in such a way that it's practical (if at all possible) to play like that. I don't know much about Guild Wars, but Skyrim (from your other question) is a prime example of this.
–
IsziJan 9 '13 at 21:17

try runes-of-magic you can use the mouse for casual gaming, in the same was as Diablo 3.
–
ParalyticJan 10 '13 at 1:24

Two questions is hardly enough to complain about a pattern, Iszi.
–
victoriahJan 10 '13 at 12:46

You can't move in exactly the same way, by clicking on the ground, but you can move using the mouse. You can hold right-click and move the mouse to look around, and if you hold right and left click at the same time, you will walk forwards.

This will allow you to move using the mouse, but you will be unable to strafe.

Holding both right-click and left-click at the same time will cause you to walk forward. This isn't the same thing as click-to-move movement, but it does allow movement to be controlled solely by the mouse.