The Glucocorticoid Receptor: A Revisited Target for Toxins. (Volume 2) - Marketon, Jeanette I. WebsterThis article is from Toxins, volume 2.AbstractThe hypothalamic-pituitary-adrenal (HPA) axis activation and glucocorticoid responses are critical for survival from a number of bacterial, viral and toxic insults, demonstrated by the fact that removal of the HPA axis or GR blockade enhances mortality rates. Replacement with synthetic glucocorticoids reverses these effects by providing protection against lethal effects...Downloads: 3