Pending High Profile Biotech IPO Should Raise Nuvilex’s Valuation

There is a buzz in certain biotech circles regarding the high value of encapsulation technologies and targeted therapy delivery platforms. Firms that have exposure to, or are major participants in these segments are just now beginning to garner significant interest from larger players, thus enabling them to enjoy increasingly favorable valuations. For example, Bind Therapeutics, Inc., a high profile biotech that recently filed to go public via an Initial Public Offering through leading health care investment banks, is one of these companies. Considering the striking similarities between Bind and Nuvilex, Inc. (OTCQB – NVLX - $0.15 – Spec Buy), Nuvilex’s shares could enjoy a big boost once Bind’s IPO registration becomes effective.

Bind is developing a therapy using what it terms Accurins. Accurins are polymeric nanoparticles that incorporate a therapeutic payload and are designed to have prolonged circulation within the bloodstream, enable targeting of the diseased tissue or cells, and provide for the controlled and timely release of the therapeutic payload at the site of disease to enhance efficacy while minimizing adverse effects on healthy tissues.

Bind’s nanomedicine platform for developing targeted therapies to treat forms of cancer has caught the eye of big pharma. The Company, which has two Phase II cancer clinical trials in progress, has already received $13M in milestone payments. To date, Bind has announced collaborations with Amgen, Pfizer and AstraZeneca to develop Accurins based on therapeutic payloads from their product pipelines, with the potential to achieve a total of over $1 billion in upfront and future milestone payments, including over $450 million in pre-commercial milestones.

If the description of the Bind Therapeutics approach sounds familiar to Nuvilex investors, it should. Both companies are engaged in developing a platform approach to targeted therapies using a prodrug to treat the targeted cancerous tissues and cells directly at the site with fewer side effects than traditional treatments. Both firms’ technology could potentially be used in conjunction with currently approved drugs for the treatment of many different forms of cancer by optimizing the anticancer activity of such drugs.

As evidenced by the development deals with big pharma, Bind Therapeutics may be ahead of Nuvilex for the time-being but we believe that Nuvilex’s stock trading pattern will closely mirror that of Bind’s and that the Company will greatly benefit from Bind’s likely high valuation as a consequence of the latter’s IPO.

For more information, refer to our previous NVLX Reports, Updates and Hot Topics by visiting www.GoldmanResearch.com

Senior Analyst: Robert Goldman Rob Goldman has over 20 years of investment and company research experience as a senior research analyst and as a portfolio and mutual fund manager. During his tenure as a sell side analyst, Rob was a senior member of Piper Jaffray's Technology and Communications teams. Prior to joining Piper, Rob led Josephthal & Co.'s Washington-based Emerging Growth Research Group. In addition to his sell-side experience Rob served as Chief Investment Officer of a boutique investment management firm and Blue and White Investment Management, where he managed Small Cap Growth portfolios and The Blue and White Fund.

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