There's a Cevat Yerli
Q&A on IGN talking with the Crytek CEO about a variety of topics. One
interesting bit, as pointed out by
Gamasutra
(thanks Mike Martinez), is his elaboration on his previous assertions about the impact of
PC piracy on sales of Crysis, as his guestimates at piracy rations are pretty
darned steep:

The other critique outside Crytek was the fact that the PC
industry is really, at the moment, I would say the most intensely pirated market
ever. It's crazy how the ratio between sales to piracy is probably 1 to 15 to 1
to 20 right now. For one sale there are 15 to 20 pirates and pirate versions,
and that's a big shame for the PC industry. I hope with Warhead I hope we
improve the situation, but at the same time it may have an impact on [our] PC
exclusivity in the future.

Obviously given that more publishers decided to use it in exclusion of other C/P methods it is effective and proves it not very valid-though obviously I "like" copy protection about as much as anyone here.

New versions tend to be pretty damn effective. The version that shipped with Bioshock wasn't cracked for over a week, no doubt that did wonders for their PC sales.