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2 Generation: activ Discover the innovative power of our latest development I N N O V Discover: Rotation + translation = mobilization Respects the anatomy Just a few steps to success Dedicated to safety 2

3 A T I O N activ L*: the first active artificial disc Aesculap was one of the pioneers in non-fusion with the Prodisc artificial disc. We have used this knowledge logically and consistently to develop the next generation of intervertebral disc prostheses generation: activ. activ L allows a range of motion that follows that of the healthy disc segment. Rotation and translation, cleverly combined, conveys for physiological mobilization. Other product features offering advantages for surgeon and patient alike are described below see for yourself! * Product not yet cleared for use in the USA. 3

4 activ L: Rotation + translation = mobilization So that patients can quickly get back to doing what they like best. M O B I L 4 Activ stands on the one hand for close approximation to physiological motion and on the other for patients who want to return quickly to active life. The site of the rotation centre in the intervertebral disc segment is a subject of repeated discussion. So it is not surprising that some conventional artificial discs either have a fixed centre of rotation in the middle or at the back of the implant. However, Gertzbein et al. have shown that the centre of rotation moves according to a rotary curve. For activ L therefore the following formula applies: rotation + translation = mobilization. With this combination of movement, activ L more closely approximates to physiological motion whilst maintaining adequate stabilization, since translation is restricted to the sagittal plane. The goal is to reduce facet joint degeneration.

5 I Z A T I O N Rotation only Purely rotational movement places more load on the facet joints. Controlled anterior-posterior translation of the core. The rotation centre is no longer fixed, but changes its position according to movement from central to dorsal. shift COR* Facet joints move against each other * Center of rotation Rotation + translation = mobilization The translation movement of the inlay prevents facet joint degeneration no shift COR* Back to active life. By the fastest route. Less strain on facet joints * Center of rotation 5

6 activ L: Respects the anatomy As individual as your patients anatomies I N D I V I D A good artificial disc should suit the patient. In the L5/S1 region we think it is important to keep the disc height low in line with the natural state. For the first time it has been possible to create an artificial disc that is only 8.5 mm high. 6

7 XL L M S Good endplate coverage is achieved by having the choice from a range of implants with small size increments. Keel version for special anatomies Optimized fixation for gaping endplates. In the special case depicted, the fins offer optimized fixation that takes effect over the entire length of the vertebra. U A L I T Y 8.5 mm Low implant heights help reduce overdistraction. The total height of 8.5 mm contributes to this goal. To avoid additional weakening of the vertebra in multisegmental treatments, the keel version can also be combined with the spike version as desired. activ L: anatomically shaped and individually adaptable. The better the contact surface between implant and bone, the lower the risk of dislocation and implant collapse. The convex shaped endplate achieves a good contact surface with the concave vertebra. 7

8 activ L: Just a few steps to success So simple, there s no excuse any more S I M P Experience has shown us that simple, clear instrumentation can contribute to surgical success. We have succeeded in reducing the operating procedure to four logical steps. 8

10 activ L: Dedicated to safety Safety is our primary concern S A F E In addition to instrumentation that makes the standardized lateral approach possible, revision instruments are also available for exceptional cases. Moreover, all sharp edged chisels are equipped with a chisel guard and safety stop. We believe this greatly reduces the risk of injury. The Plasmapore coating, that has proved its worth over many years, is used in combination with additional calcium phosphate layer to guarantee high primary and secondary stability. 10

12 All rights reserved. Technical alterations are possible. This leaflet may be used for no other purposes than offering, buying and selling of our products. No part may be copied or reproduced in any form. In the case of misuse we retain the rights to recall our catalogues and pricelists and to take legal actions. Aesculap AG & Co. KG Am Aesculap-Platz Tuttlingen Phone Fax Brochure No. O /2/2

Aesculap Spine activ C Cervical Disc Prosthesis Retain Mobility activ C Back to life enjoyed to the full I N N O V A Natural mobility Safety during surgery and in everyday life Stability in every situation

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