A suicidal children's author (Amy Irving) has a seizure just before trying to kill herself, and House, who's a fan, thinks that the key to both her physical and psychological conditions lies in her latest book. Meanwhile, House and Cuddy go on a double dat (more…)A suicidal children's author (Amy Irving) has a seizure just before trying to kill herself, and House, who's a fan, thinks that the key to both her physical and psychological conditions lies in her latest book. Meanwhile, House and Cuddy go on a double date with Wilson and his girlfriend, Sam (Cynthia Watros).

A patient who can't stop vomiting is also hiding secrets. Meanwhile, House turns a cold shoulder to Chase's new hire, and House and Cuddy must look anew at their relationship following a visit from House's massage therapist.

The mother (Jennifer Grey) of a newborn with breathing difficulties and liver failure must make a very difficult decision that could affect her own health as well as her baby's. Meanwhile, Cuddy tells House to hire a woman for his team, and he delegates th (more…)The mother (Jennifer Grey) of a newborn with breathing difficulties and liver failure must make a very difficult decision that could affect her own health as well as her baby's. Meanwhile, Cuddy tells House to hire a woman for his team, and he delegates the task to Foreman and Taub. Cuddy also asks House to babysit her daughter, Rachel, and he and Wilson learn a parenting lesson in the process.

At Cuddy's insistence, House finally hires a female member of the team, a third-year medical student (Amber Tamblyn) who, it turns out, has a tie to Taub. Meanwhile, a senator's campaign manager (Jack Coleman) suddenly falls ill, and the team must look to (more…)At Cuddy's insistence, House finally hires a female member of the team, a third-year medical student (Amber Tamblyn) who, it turns out, has a tie to Taub. Meanwhile, a senator's campaign manager (Jack Coleman) suddenly falls ill, and the team must look to the candidate (Pat Finn) for clues about his condition. They also must get Cuddy's approval for their course of treatment.

A girl is suspected of having smallpox after a 200-year-old medicine jar found in a shipwreck shatters in her hand, so a CDC doctor (Dylan Baker) locks down the hospital. Martha Masters (Amber Tamblyn) questions his motive for doing so. She also questions (more…)A girl is suspected of having smallpox after a 200-year-old medicine jar found in a shipwreck shatters in her hand, so a CDC doctor (Dylan Baker) locks down the hospital. Martha Masters (Amber Tamblyn) questions his motive for doing so. She also questions the diagnosis. Meanwhile, Wilson and Sam (Cynthia Watros) examine their relationship after they comfort a 6-year-old cancer patient (Devon Woods).

A man (Kuno Becker) falls ill after reenacting the Crucifixion; Taub questions his wife (Jennifer Crystal Foley) about her relationship with a member of an infidelity support group; Wilson's relationship with Sam (Cynthia Watros) takes a sudden turn after (more…)A man (Kuno Becker) falls ill after reenacting the Crucifixion; Taub questions his wife (Jennifer Crystal Foley) about her relationship with a member of an infidelity support group; Wilson's relationship with Sam (Cynthia Watros) takes a sudden turn after they attend a co-worker's wedding.

A hero (Matthew Lillard) collapses moments after risking his life to save a stranger who fell onto subway tracks. Meanwhile, House tries to avoid Cuddy's birthday dinner because her opinionated mother (Candice Bergen) will be there; and Masters (Amber Tamb (more…)A hero (Matthew Lillard) collapses moments after risking his life to save a stranger who fell onto subway tracks. Meanwhile, House tries to avoid Cuddy's birthday dinner because her opinionated mother (Candice Bergen) will be there; and Masters (Amber Tamblyn) helps Taub realize that he must take action on his crumbling marriage.

The team tries to link symptoms of a teenager at a military-style juvenile-offender camp and his drill sergeant; House secretly helps Cuddy's daughter get into a prestigious preschool; an embarrassing photo of Chase turns up on a social-networking site.

When Cuddy's mother (Candice Bergen) is admitted to the hospital, she won't let House treat her. But the team does anyway, and discovers secrets she and her other daughter (Paula Marshall) kept from Cuddy. And the case's ethical issues bother Masters more (more…)When Cuddy's mother (Candice Bergen) is admitted to the hospital, she won't let House treat her. But the team does anyway, and discovers secrets she and her other daughter (Paula Marshall) kept from Cuddy. And the case's ethical issues bother Masters more than usual. Meanwhile, Taub takes a part-time job as a medical investigator for Rachel's brother, a lawyer.

A waitress with an extraordinary memory (Tina Holmes) suffers a paralysis, and her recovery is complicated by an anything-but-forgotten grudge she holds against her older sister (Claire Rankin). Meanwhile, House discovers Wilson's secret new companion when (more…)A waitress with an extraordinary memory (Tina Holmes) suffers a paralysis, and her recovery is complicated by an anything-but-forgotten grudge she holds against her older sister (Claire Rankin). Meanwhile, House discovers Wilson's secret new companion when he tries to help him return to the dating scene; and Foreman helps Taub prepare for a medical exam.

House participates in a school career day---and breaks rules by sharing explicit medical stories. Later, two fifth graders (Austin Michael Coleman and Haley Pullos) assess House's relationship troubles with Cuddy, and try to help him understand the role th (more…)House participates in a school career day---and breaks rules by sharing explicit medical stories. Later, two fifth graders (Austin Michael Coleman and Haley Pullos) assess House's relationship troubles with Cuddy, and try to help him understand the role that his selfish antics play in them.

A man who had lied to his wife about losing his lucrative real-estate position is hospitalized with a severe rash caused by chemical exposure at his blue-collar job. The case's complications lead to an existential crisis for House, and that complicates thi (more…)A man who had lied to his wife about losing his lucrative real-estate position is hospitalized with a severe rash caused by chemical exposure at his blue-collar job. The case's complications lead to an existential crisis for House, and that complicates things with Cuddy, who needs his support at a charity event. Meanwhile, Chase and Masters teach each other a lesson in how to forge relationships.

A bombshell that hits Cuddy causes her to rethink her priorities, distracting House as the team tries to diagnose a troubled teen whose mysterious scars point to emotional as well as physical woes. Cuddy's mental state is encapsulated in dream sequences, o (more…)A bombshell that hits Cuddy causes her to rethink her priorities, distracting House as the team tries to diagnose a troubled teen whose mysterious scars point to emotional as well as physical woes. Cuddy's mental state is encapsulated in dream sequences, one of which was choreographed by Mia Michaels ("So You Think You Can Dance").

A bullfighter is admitted after being attacked by a bull, and Masters develops a crush on him as his condition inexplicably worsens, with miniseizures that can't be explained. Meanwhile, House is away from the hospital, tending to other issues.

A young homeless man with a history of drug abuse (and a secret) arrives at the hospital with bad burns and scars on his chest. Meanwhile, Cuddy tells Wilson that she feels guilty about breaking up with House.

Thirteen reappears. It seems that she has just been released from prison, and House wants to know why she landed there. He seeks answers as they team up in a spud-gun competition. Meanwhile, the team treats a science teacher with a respiratory illness who (more…)Thirteen reappears. It seems that she has just been released from prison, and House wants to know why she landed there. He seeks answers as they team up in a spud-gun competition. Meanwhile, the team treats a science teacher with a respiratory illness who turns out to be a hoarder; and Taub dips his toe into the dating pool.