Advancements in Pharmaceutics

It encompasses a molecular evaluation of drug metabolism and transport processes and the study of genetic, environmental and disease-related factors that regulate or perturb those processes, as well as the fundamental mathematical relationships between enzyme/transporter function, blood concentration-time profiles and the spectrum of pharmacological effects.

The global market for contract pharmaceutical manufacturing, research and packaging totalled $248.5 billion in 2014 and is projected to approach $352.8 billion by 2019, registering a compound annual growth rate (CAGR) of 7.3% through 2019.

There are a number of important preformulation considerations for the development of “fit for purpose” formulations. Basic understanding of compound’s physicochemical and biopharmaceutical properties is very important for the development of any drug product. Technologic & conceptual advances in pharmacokinetics, pharmacodynamics, and drug metabolism may be usefully applied to the evaluation of drug interactions.