Targeting Btk/Etk of Prostate Cancer Cells by a Novel Dual Inhibitor
Scientists found that Btk is overexpressed in prostate cancer tissues and prostate cancer cells. The level of Btk in prostate cancer tissues correlates with cancer grades. Knockdown of Btk expression selectively inhibits the growth of prostate cancer cells, but not that of the normal prostate epithelial cells, which express very little Btk. [Cell Death Dis] Full Article