Getting to the Citadel in Mass Effect. Just the size of that place, and the game in general, was unlike anything I'd really experienced. There were many more memorable moments in that entire series, but that was really my first "Wow" moment.

it was recently actually. the ending to the entire ending of the last of us ####******SPOILERS*******###### having to fight off about 43 people on survivor mode to get to ellie and then kicking open the doors to find the doctors with her on the table...as soon as i opened that door i popped all those bitches in the head with one shot i felt like john wayne or clint eastwood. it was very memorable as well to find out that joel and ellie made it out alive together...hopefully naughty dog makes this a trilogy =]