It’s summertime in the desert, once again, and this weekend is expected to usher in the season in unforgiving fashion.

The National Weather Service has issued an excessive heat warning for Saturday through June 21 for Southern Nevada, Northwest Arizona and Southeastern California.

According to NWS, temperatures in the Las Vegas Valley are expected to range from 100 to 115 degrees. Temperatures in Death Valley and along the Colorado River Valley are expected to get as high as 120.

The Weather Channel forecasts temperatures in Mesquite to be between 111 and 117 degrees from Saturday through Wednesday.

To combat the unrelenting heat — elevated overnight temperatures are also expected — NWS recommends drinking necessary amounts of water, wearing light clothes, using sunscreen when outside, and minimizing outdoor activities between the hours of 11 a.m. and 6 p.m.

Those most at risk, according to a release from NWS, are children and pets in vehicles, the homeless, elderly, and people with existing health issues.

“This also includes visitors not from the Desert Southwest who may be unaccustomed to these types of temperatures,” the release reads.

In 2016, 33 people died in Clark County as a direct result of heat, according to Reid Wolcott, senior meteorologist for the National Weather Service in Las Vegas. There were also 22 deaths that were indirectly attributed to heat.

Follow Lucas Thomas on Twitter, @LucasThomas14, or call him at 702-232-0603.