Compare Mucinex DM vs. Mucinex D

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Breaks up mucus and relieves cough. Mucinex Dm (Dextromethorphan / Guaifenesin) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. It comes as an extended-release tablet and a short-acting liquid.

Breaks up mucus and relieves congestion. Mucinex D (Guaifenesin / Pseudoephedrine) is good if you have a stuffy nose and a cough with mucus, but it could keep you up at night.

Find lowest prices

Save on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.

› Mucinex Dm (Dextromethorphan / Guaifenesin) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.

› Helps loosen the mucus and phlegm that builds up in productive and wet coughs.

› The extended release version of Mucinex DM lasts up to 12 hours.

› Mucinex D (Guaifenesin / Pseudoephedrine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have sinus and chest congestion.

› Helps loosen the mucus in your airways so that you can cough it up more easily.

› Works well to clear nasal congestion and help you breathe better.

Downsides and risks

Mucinex DM

Mucinex D

› Mucinex Dm (Dextromethorphan / Guaifenesin) isn’t useful if you have a dry cough without mucus or phlegm.

› The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Mucinex Dm (Dextromethorphan / Guaifenesin)) stops you from coughing.

› Can cause sleepiness, dizziness, and an upset stomach.

› Pseudoephedrine, the decongestant in Mucinex D (Guaifenesin / Pseudoephedrine), can make your heart race or make you feel anxious and restless.

› Doesn't work as well if you use it for more than 4 days at a time.

› Although you don't need a prescription to get Mucinex D (Guaifenesin / Pseudoephedrine), you need to show a photo ID to buy it in the drugstore.