We detected African-specific SNPs at ZNF649 and LSAMP, with associations of genome-wide significance for ulcerative colitis.

A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men

The results showed significant allelic and haplotypic associations between LSAMP gene and schizophrenia.

The tumor suppressor function of LSAMP is most likely exerted by reducing the proliferation rate of the tumor cells, possibly by indirectly upregulating one or more of the genes HES1 (Montrer HES1 Kits ELISA), CTAG2 or KLF10 (Montrer KLF10 Kits ELISA).

This study presents the first evidence of a possible role of LSAMP gene in mood and anxiety disorders in humans.

proteomic assessments of membrane microdomains in prefrontal cortex and validation in two brain series, strongly implicates LAMP, STXBP1 and BASP1 (Montrer BASP1 Kits ELISA) in schizophreina and supports the view of a neuritic and synaptic dysfunction in the neuropathology

Single nucleotide polymorphisms of LSAMP is associated with the pathogenesis of coronary artery disease.

LSAMP might play a role in pathoaetiology of suicidal behaviour but further studies are needed to understand its exact contribution

results show that LSAMP is a novel candidate tumor suppressor gene in osteosarcomas

genomic features of the Lsamp gene indicate an intricate mechanism of gene expression regulation that may be relevant in the context of human neuropsychiatric and neurological disorders, where LAMP expression may be altered

Limbic System-Associated Membrane Protein (LSAMP) profil antigène

Antigen Summary

The protein encoded by this gene is a neuronal surface glycoprotein found in cortical and subcortical regions of the limbic system. During development of the limbic system, this encoded protein is found on the surface of axonal membranes and growth cones, where it acts as a selective homophilic adhesion molecule, and guides the development of specific patterns of neuronal connections.