She made her film debut in 1912 with Dream Paintings, and after that followed a number of movies:

The Lure of London ‎(1914)‎
The Girl from the Sky ‎(1914)‎
The Ware Case ‎(1917)‎
The Adventures of Dick Dolan ‎(1917)‎
Nelson ‎(1918)‎
The Flag Lieutenant ‎(1919)‎
The Worldlings ‎(1920)‎
La roue ‎(1923)‎

and the German productions:

Der fidele Bauer ‎(1927)‎
Die Hölle der Jungfrauen ‎(1928)‎

With Ivy Close also began a film dynasty which comprise four generations. Her son Derek Neame was a scriptwriter, her son Ronald Neame became a celebrated cinematographer and director. Her grandson Christopher Neame and her great-grandson Gareth Neame both became producers.