I don't know what is best for you, but I will share what I believe and do. I take the RMD fairly late in the year to allow the tax deferral work for as long a possible. The RMD is taken in a manner to maintain or rebalance to my desired asset allocation. This usually means that I take a proportionate share from all funds.It seems to me that if you withdraw from the poor performer(s) you are selling low and presumably buying high.

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