noun 1. Anatomy. an antibody-secreting cell, derived from B cells, that plays a major role in antibody-mediated immunity. plasma cell n. An antibody-producing lymphocyte derived from a B cell upon reaction with a specific antigen. Also called plasmacyte. plasma cell A lymphocyte that originates from a B cell and produces antibodies as part of a […]

plasma cell leukemia n. A disease characterized by leukocytosis and other symptoms suggestive of leukemia and associated with diffuse infiltration and aggregation of plasma cells in the spleen, liver, bone marrow, and lymph nodes and by significant numbers of plasma cells in the blood.

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