Boren, McIntyre and Ross had voted in favor of repeal the first time it came to a vote on January 19, 2011 and have voted to remove funding from or rescind parts of the bill multiple times since then.

Matheson and Kissell voted against full repeal in 2011. However, in March of this year they joined five other Democrats in voting for the repeal of an independent advisory board created by the law. In April, they joined 11 other Democrats in approving a bill that would pay to keep student loan interest rates from doubling by chopping parts of the health care law.

Boren said in a statement that the law was “too large and too costly.”

“In addition, an overwhelming majority of my constituents have urged me to support the repeal of the health care law,” he said.

All five Democrats also defected from the Democratic majority a few weeks ago to vote in favor of holding Attorney General Eric Holder in contempt of Congress.

The vote, which passed 244-285, is the thirty-third the House has taken against the law since Republicans won control of the chamber in 2010.