Star fruit, so named because it has five prominent ridges that make it star-shaped on cross section, is the yellow- or green-skinned fruit of the carambola tree. Because it contains high levels of oxalic acid, it is typically sour and its juice can be used to remove stains from clothing. Like grapefruit, star fruit possesses compounds that make it dangerous to consume when taking certain medications, including those used to treat what kind of conditions? More...

Article of the DayStar FruitStar fruit, so named because it has five prominent ridges that make it star-shaped on cross section, is the yellow- or green-skinned fruit of the carambola tree. Because it contains high levels of oxalic acid, it is typically sour and its juice can be used to remove stains from clothing.

Carambola (Averrhoa Starfruit) belongs to the oxalidacea family of fruits. ... Carambola has a neurotoxin capable of causing neurological disorders in patients with Chronic Kidney Disease (CKD), involving changes such as hiccups and mental confusion to severe conditions such as seizures and death.This neurotoxin seems to inhibit the GABAergic system, which is the main inhibitory system of the central nervous system (CNS), formed by neurons containing gammaaminobutyric acid (GABA). The cell membranes of most CNS neurons and astrocytes express GABA receptors, which decrease neuronal excitability via a variety of mechanisms. Because of its widespread distribution, GABA receptors influence many neural circuits and functions.

However, new studies have been carried out to clarify the mechanism by which carambola becomes toxic to individuals with CKD; thus justifying this review paper to discuss and disclose new evidence on the subject. It is important that healthcare professionals know the real effects and mechanisms by which carambola can be lethal to patients in this clinical situation.

Carambola (Averrhoa Starfruit) belongs to the oxalidacea family of fruits. ... Carambola has a neurotoxin capable of causing neurological disorders in patients with Chronic Kidney Disease (CKD), involving changes such as hiccups and mental confusion to severe conditions such as seizures and death.This neurotoxin seems to inhibit the GABAergic system, which is the main inhibitory system of the central nervous system (CNS), formed by neurons containing gammaaminobutyric acid (GABA). The cell membranes of most CNS neurons and astrocytes express GABA receptors, which decrease neuronal excitability via a variety of mechanisms. Because of its widespread distribution, GABA receptors influence many neural circuits and functions.

However, new studies have been carried out to clarify the mechanism by which carambola becomes toxic to individuals with CKD; thus justifying this review paper to discuss and disclose new evidence on the subject. It is important that healthcare professionals know the real effects and mechanisms by which carambola can be lethal to patients in this clinical situation.

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