Natural Ways to Lower Plasma Norepinephrine?

My high norepinephrine level is responsible for many of my symptoms (nausea, burning skin, agitatie, immunesuppression and anxiety). Deep breathing (lowers norepinephrine) is working very well for me. I was wondering if I could extend this benefit by reducing norepinephrine even further with supplements.

phosphatidyl serine can help lower cortisol levels, cortisol is basically a long acting adrenaline so controlling it would help. I have had some success with this at night with tryptophan for sleep, in saying this im not the best sleeper in the world by a long shot, but this has helped.

My high norepinephrine level is responsible for many of my symptoms (nausea, burning skin, agitatie, immunesuppression and anxiety). Deep breathing (lowers norepinephrine) is working very well for me. I was wondering if I could extend this benefit by reducing norepinephrine even further with supplements.

Anyone experience with norepinephrine lowering supplements?
I need some advice...

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Hi, Emmotje.

Lifting a partial block in the methylation cycle will help to lower norepinephrine in two ways. One is that it raises SAMe, which is used by COMT to break down norep as you mentioned. The other is that SAMe is needed to convert norep to epinephrine.

Lifting a partial block in the methylation cycle will help to lower norepinephrine in two ways. One is that it raises SAMe, which is used by COMT to break down norep as you mentioned. The other is that SAMe is needed to convert norep to epinephrine.