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Herpes Zoster; Post-herpetic Neuralgia

Duragesic

Herpes zoster, colloquially known as shingles, is the reactivation of varicella zoster virus, leading to a crop of painful blisters over the area of a dermatome. It occurs very rarely in children and adults, but its incidence is high in the elderly (over 60), as well as in any age group of immunocompromised patients. It strikes 500,000 people per year in the United States. Treatment is generally with acyclovir. Many develop a painful condition termed postherpetic neuralgia.

Duragesic is the trade name of a fentanyl transdermal therapeutic system manufactured by ALZA Corporation and marketed by Janssen Pharmaceutica Products, L.P. A generic version was under development by Mylan Laboratories Inc. for launch in January 2005.

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