Insulin Resistance: The Metabolic Syndrome X / Edition 1

Gerald Reaven, the discoverer of Syndrome X, and a panel of world-clas s investigators thoughtfully summarize our current understanding of ho w insulin resistance and its compensating hyperinsulinemia play a majo r role in the pathogenesis and clinical course of high blood pressure and cardiovascular diseaseythe so-called diseases of Western civilizat ion. These

Overview

Gerald Reaven, the discoverer of Syndrome X, and a panel of world-clas s investigators thoughtfully summarize our current understanding of ho w insulin resistance and its compensating hyperinsulinemia play a majo r role in the pathogenesis and clinical course of high blood pressure and cardiovascular diseaseythe so-called diseases of Western civilizat ion. These distinguished authorities detail, for the first time, the p athophysiological consequences and the clinical syndromes, excluding T ype 2 diabetes, related to insulin resistance. They also examine the g enetic and lifestyle factors that contribute to the wide differences i n insulin action that exist in the population at large. Timely and aut horitative, Insulin Resistance: The Metabolic Syndrome X illuminates t he full importance of insulin resistance as a major cause of hypertens ion, heart disease, and polycystic ovary syndrome.