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Of the three choices you've offered, it would be fair to say that number three is the least accurate. With that said, number two is probably the most widely accepted area of the Lowcountry.

There is not a clearly defined boundary of the Lowcountry. Some will say it extends north of Charleston and some will say it extends just south of, but also includes Charleston. Others will say that it also includes all of the SC coast and areas as far west as Orangeburg.

This is the only map that I could find that I would consider to be the most accurate. I'm not sure why it's rotated.

South Carolina has four geographic regions. Areas north of Charleston County are not the Grand Strand but are collectively considered the Pee Dee region. The other regions are the Lowcountry, the Midlands and the Piedmont.