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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

It has been demonstrated that although pregabalin is a structural derivative of the inhibitory neurotransmitterGABA, it does notbind directly to GABAA, GABAB, or benzodiazepine receptors, does not augment GABAA responses in vitro, does not alter GABA concentration in the animal brain, or have acute effects on GABA uptake or degradation (Lyrica®).