What does this research study involve?

You will not undergo tests or procedures that are not required as part of your routine clinical care. We will ask you to provide additional samples from tissue that is obtained for your clinical care.

We plan to do research on how genes influence the behavior of cancers. We also plan to do non-genetic tests that are relevant to your disease such as the effect of immune regulation on disease progression.

This will be done by performing analyses on your tissues (obtained during your routine lymph node or bone marrow biopsies), blood, or other body fluids, such as saliva or urine. We will also use tissue specimens that have already been collected and stored as part of your clinical care. Analyses will be performed on material only after all necessary clinical tests have been performed. However, we are asking your permission to obtain additional samples of blood (2-4 tablespoons), bone marrow (1.5 tablespoons), a urine sample, and a swab from the inside of your mouth or a mouthwash. These are sources of both cancer cells and of non-cancer cells, which are needed for some types of analyses.