The opening sketch wasn't the only part of the premiere that hammered the President regarding Puerto Rico. "Weekend Update" co-host Michael Che laid into the President over his response.

"After the mayor of San Juan criticized the federal government relief efforts, President Trump attacked her on Twitter saying, 'The Mayor of San Juan, who was very complimentary only a few days ago, has now been told by the Democrats that you must be nasty to Trump,'" Che said. "Oh really, Donald? You bitch. Was she nasty to you? How nasty? Are you shaking? Do you want to go smoke a Virginia Slim until your hand stops moving?"

Michael Che hammers Trump on @nbcsnl over the Puerto Rico response. "You just did this for white people twice." Also calls him "you bitch." pic.twitter.com/kGXEkcIENU

Che then retorted, "This isn't that complicated, man. It's hurricane relief. These people need help. You just did this for white people twice."

Away from Puerto Rico, the opening sketch also brought on Kate McKinnon as Attorney General Jeff Sessions and commented on Trump's attacks on NFL players who kneel during the National Anthem in protest of social and racial injustice.

Jay Z, the show's musical guest, made a statement of his own during his musical performance on Saturday night.