Resveratrol and Testosterone: Natural Estrogen Blocker

Resveratrol is a naturally occurring polyphenol found in the skin of red grapes, mulberries, and blueberries. Its popularity has been soaring these past years due to research theorizing the compound of having an anti-aging, cardiovascular health promoting, and anti-cancer effects.

Resveratrol is the compound also claimed to cause the health benefits of red wine, although a normal sized wine bottle only contains ~2mg’s of resveratrol, a dose so small that it will surely not affect anything health-wise…

…At higher doses though, resveratrol has been found to raise testosterone levels, block estrogen synthesis, and possibly activate androgen receptors, there are few “problems” with these studies though.

Resveratrol, Testosterone, Estrogen…

Resveratrol is produced in plants by the actions of an enzyme called resveratrol-synthase. Interestingly enough, it’s an antioxidant phytoalexin, otherwise known as a plant-toxin that is only synthesized as a defense mechanism of plants when they are attacked by an infection.

The research on resveratrol supplementation is very interesting, although there’s a good reason why most supplements containing this phenol will have absolutely no effects inside the body after consumption, as it just happens to be that the compound has incredibly low bio-availability in humans (more about this soon).

Aside from increasing sTAR, resveratrol can increase testosterone levels through another mechanism too, and that is, by inhibiting the enzyme aromatase, which converts testosterone into estrogen. This effect has been seen in multiple in-vitro (test-tube) studies (study, study, study).

Conclusion

I was intrigued by the bold headlines of resveratrol benefits over these years, but never really felt like recommending in it due to the fact that I had also seen the research of its low bioavailability in the human body. Only after finding out the research on the VESIsorb® (affiliate link) delivery methods effectiveness, I feel comfortable enough to recommend the supplement without losing my sleep.

The sad truth is that most of the supplement manufacturers who have been pushing resveratrol over the years also knew that it doesn’t really reach the target tissues in the free trans-resveratrol form, but they’ve sold it anyway! This perfectly showcases the true nature of the supplement industry. If people buy, they’ll sell anything, whether it works or not is irrelevant.

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Medical Disclaimer

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†Disclaimer: These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Product results may vary from person to person.