Objective: The aim of this study was to determine the incidence of disorders of higher nervous functions in patients who suffered ischemic stroke, to determine the demography, the sex structure of the patients and the presence of higher nervous functions disorders by TOAST classification. Study design: Cross-sectional study Participants and methods: The study included 100 patients treated at Clinical Hospital Centre Osijek for the ischemic stroke in the acute phase of the disease. Each patient was classified by age, sex and TOAST classification of stroke based on the CT findings. Any patient suspected of having aphasia was referred to a speech therapist who diagnosed the exact aphasia if there had been any. Other nervous functions (agraphia, alexia, acalculia, apraxia and agnosis) were tested under the supervision of a mentor and a clinical psychologist. Results: Of all patients who suffered the ischemic stroke, 54% had at least one disorder of higher nervous functions. Aphasia accounted for 75% of all disorders. Global aphasia is the most common disorder of the higher nervous functions and was mainly found in those with ischemic stroke over the age of 75. Higher nervous function disorders are most commonly reported in patients with the stroke of larger blood vessels and cardioembolic stroke, but without any statistical significance. Disorders of higher nervous functions did not show statistically significant distribution by age and sex. Conclusion: More than 50% of patients who suffered the ischemic stroke have at least one of the disorders of higher nervous functions. Though aphasia is the most commonly known disorder, attention should be paid to other disorders as well, since they often remain undetected in clinical practice.