..Chronic hypertension is a common medical condition in pregnancy. The purpose of the study was to examine the association between maternal chronic hypertension and the risk of congenital malformations in the offspring...

..Intravenous vancomycin exposure has been identified as an independent risk factor for CDI, but this is controversial. It is not known whether vancomycin administered for surgical site infection prophylaxis increases the risk of CDI...

The risk and outcomes of epidural hematomas after perioperative and obstetric epidural catheterization: a report from the Multicenter Perioperative Outcomes Group Research Consortium

..1%) in the third trimester. Antihypertensive use during pregnancy is relatively common and increasing. The wide range of agents used during pregnancy includes medications considered contraindicated during pregnancy...

Hypertension in women of reproductive age in the United States: NHANES 1999-2008

..In this study, we sought to (1) define trends in the incidence of postpartum hemorrhage (PPH), and (2) elucidate the contemporary epidemiology of PPH focusing on risk factors and maternal outcomes related to this delivery complication...

Development of a comorbidity index for use in obstetric patients

Brian T BatemanDivision of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, The Department of Anesthesiology, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, and the Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts the Department of Anesthesiology, University of Michigan Health System, Ann Arbor, Michigan and the Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GeorgiaObstet Gynecol 122:957-65. 2013

Calcium Channel Blocker Exposure in Late Pregnancy and the Risk of Neonatal Seizures

Brian T BatemanDivision of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, and the Division of Endocrinology, Diabetes and Metabolism, Brigham and Women s Hospital and Harvard Medical School, the Departments of Anesthesiology, Critical Care, and Pain Medicine and Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, and the Department of Epidemiology, Harvard School of Public Health, Boston, MassachusettsObstet Gynecol 126:271-8. 2015

..The objective of this analysis was to evaluate the frequency, distribution of potential etiologies, and survival rates of maternal cardiopulmonary arrest during the hospitalization for delivery in the United States...

Methylergonovine maleate and the risk of myocardial ischemia and infarction

..There are few data regarding the utilization of opioids during pregnancy. The objective of this study was to define the prevalence and patterns of opioid use in a large cohort of pregnant women who were commercial insurance beneficiaries...

Massive blood transfusion during hospitalization for delivery in New York State, 1998-2007

Jill M MhyreDepartment of Anesthesiology, University of Michigan Health System, Ann Arbor, Michigan the Department of Obstetrics and Gynecology, New York Medical College, Valhalla, New York the Division for Heart Disease and Stroke Prevention and the Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia and the Department of Anesthesiology, Critical Care, and Pain Medicine, Massachusetts General Hospital, Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MassachusettsObstet Gynecol 122:1288-94. 2013

..To define the frequency, risk factors, and outcomes of massive transfusion in obstetrics...

Development and validation of a score for prediction of postoperative respiratory complications

..However, the proportion of patients who actually receive this evidence-based approach is unknown. The objective of this study was to describe hospital-level patterns in the utilization of perioperative multimodal analgesia...

Exposure to prescription opioid analgesics in utero and risk of neonatal abstinence syndrome: population based cohort study

..The late 1990s/early 2000s was a time of change in both the prevention and acute care of ischemic stroke, with primary prevention driven by increased utilization of antihypertensive, antiplatelet, anticoagulation, and lipid-lowering agents...

Lisa R LeffertObstetric Anesthesia Division, Department of Anesthesia, and Department of Anesthesia, Critical Care and Pain Medicine, and the Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts and the Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GeorgiaObstet Gynecol 125:124-31. 2015

....

Patterns of second-line uterotonic use in a large sample of hospitalizations for childbirth in the United States: 2007-2011

..3% and 0.5% of all pregnancies occur among women with epilepsy. Evidence suggests an increase in perinatal morbidity and mortality among women with epilepsy. However, these risks have not been quantified in large population-based samples...

..To estimate nationwide trends in the prevalence of maternal congenital heart disease (CHD) and determine whether women with CHD are more likely than women without maternal CHD to have medical and obstetric complications...