Does anyone know how the misc profiles starting with CDO__o_... in the Profiles registry key under HKCU\Software\Microsoft\Windows NT\Current Version\Windows Messaging Subsystem get flushed?

Are they supposed to disappear on their own or is a reboot supposed to clear them? Most of my servers (all have around 700-800 user) have a ton of them, probably over 300.

I'm seeing a similar thing. I deleted these when I recreated the MAPI profile but some came back after restarting the BES server. Does anyone know what may cause this? The users that are listed seem to be having message delays to their devices.