Bioinformatics, a hybrid science that links biological data with techniques for information storage, distribution, and analysis to support multiple areas of scientific research, including biomedicine. Bioinformatics is fed by high-throughput data-generating experiments, including genomic sequence

Tatiana Bilbao: …was a multiuse biotechnology facility, Bioinnova (completed in 2012), that Bilbao and her team designed for the Monterrey Institute of Technology’s campus there. Like Bilbao’s other work, Bioinnova was inspired by a mix of geometry and nature—in this case, the form of a tree. Rather than producing a standard Modernist…

Bioko, island in the Bight of Biafra (Gulf of Guinea), lying about 60 miles (100 km) off the coast of southern Nigeria and 100 miles (160 km) northwest of continental Equatorial Guinea, western Africa. The island was named after the first president of the country in 1973, but Bioko became the local

Christian fundamentalism: The late 19th to the mid-20th century: …(founded in 1886) and the Bible Institute of Los Angeles (founded in 1908), not only provided instruction to their students but assumed many of the duties formerly performed by denominational institutions. They published periodicals, broadcast from their own radio stations, held conferences, and maintained a staff of extension speakers. Indeed,…

synthetic biology: History of synthetic biology: …led to the production of biologic drugs, agents made from proteins and other organic compounds produced by bacteria with recombinant DNA; one such compound is synthetic insulin. However, because genetic engineering uses existing genes and bacteria, it has technical limitations and is expensive.

Biological Weapons Convention (BWC), international treaty that bans the use of biological weapons in war and prohibits all development, production, acquisition, stockpiling, or transfer of such weapons. The convention was signed in London, Moscow, and Washington, D.C., on April 10, 1972, and

Physical anthropology, branch of anthropology concerned with the origin, evolution, and diversity of people. Physical anthropologists work broadly on three major sets of problems: human and nonhuman primate evolution, human variation and its significance (see also race), and the biological bases of

nanotechnology: Bioassays:
A second area of intense study in nanomedicine is that of developing new diagnostic tools. Motivation for this work ranges from fundamental biomedical research at the level of single genes or cells to point-of-care applications for health delivery services. With advances in molecular biology,…

Classification, in biology, the establishment of a hierarchical system of categories on the basis of presumed natural relationships among organisms. The science of biological classification is commonly called taxonomy

biological rhythm: …environmental stimulus is termed a biological clock. When an animal that functions according to such a clock is rapidly translocated to a geographic point where the environmental cycle is no longer synchronous with the animal’s cycle, the clock continues for a time to function synchronously with the original environmental cycle.…

Coloration, in biology, the general appearance of an organism as determined by the quality and quantity of light that is reflected or emitted from its surfaces. Coloration depends upon several factors: the colour and distribution of the organism’s biochromes (pigments), particularly the relative

Community, in biology, an interacting group of various species in a common location. For example, a forest of trees and undergrowth plants, inhabited by animals and rooted in soil containing bacteria and fungi, constitutes a biological community. A brief treatment of biological communities follows.

Biological control, the use of living organisms to control pests. A natural enemy such as a parasite, predator, or disease organism is introduced into the environment of a pest or, if already present, is encouraged to multiply and become more effective in reducing the number of pest organisms.

Biological rhythm, periodic biological fluctuation in an organism that corresponds to, and is in response to, periodic environmental change. Examples of such change include cyclical variations in the relative position of Earth to the Sun and to the Moon and in the immediate effects of such

Biological determinism, the idea that most human characteristics, physical and mental, are determined at conception by hereditary factors passed from parent to offspring. Although all human traits ultimately are based in a material nature (e.g., memorizing a poem involves changing molecular

Biological development, the progressive changes in size, shape, and function during the life of an organism by which its genetic potentials (genotype) are translated into functioning mature systems (phenotype). Most modern philosophical outlooks would consider that development of some kind or other

Biodiversity, the variety of life found in a place on Earth or, often, the total variety of life on Earth. A common measure of this variety, called species richness, is the count of species in an area. Colombia and Kenya, for example, each have more than 1,000 breeding species of birds, whereas the

Convention on Biological Diversity, international treaty designed to promote the conservation of biodiversity and to ensure the sustainable use and equitable sharing of genetic resources. Work on the treaty concluded in Nairobi in May 1992 with the adoption of the Nairobi Final Act by the Nairobi

Columbian Exchange: …a more general process of biological globalization that followed the transoceanic voyaging of the 15th and 16th centuries. Ecological provinces that had been torn apart by continental drift millions of years ago were suddenly reunited by oceanic shipping, particularly in the wake of Christopher Columbus’s voyages that began in 1492.…

Malformation, in biology, irregular or abnormal structural development. Malformations occur in both plants and animals and have a number of causes. The processes of development are regulated in such a way that few malformed organisms are found. Those that do appear may, when properly studied, shed

Membrane, in biology, the thin layer that forms the outer boundary of a living cell or of an internal cell compartment. The outer boundary is the plasma membrane, and the compartments enclosed by internal membranes are called organelles. Biological membranes have three primary functions: (1) they

Biomolecule, any of numerous substances that are produced by cells and living organisms. Biomolecules have a wide range of sizes and structures and perform a vast array of functions. The four major types of biomolecules are carbohydrates, lipids, nucleic acids, and proteins. Among biomolecules,

alcohol: Biological oxidation:
All substances are toxic if taken in large enough quantities, and alcohols are no exception. Although ethanol is less toxic than methanol, it is nonetheless a poisonous substance, and many people die each year from ethanol poisoning. When someone is suffering from mild…

reproductive behaviour: Natural selection and reproductive behaviour: …favourable rather than less favourable period will eventually dominate succeeding generations. This is the basis for the seasonality of reproduction among most animal species.

Toxin, any substance poisonous to an organism. The term is sometimes restricted to poisons spontaneously produced by living organisms (biotoxins). Besides the poisons produced by such microorganisms as bacteria, dinoflagellates, and algae, there are toxins from fungi (mycotoxins), higher plants

inland water ecosystem: Biological productivity:
Central to all biological activity within inland aquatic ecosystems is biological productivity or aquatic production. This involves two main processes: (1) primary production, in which living organisms form energy-rich organic material (biomass) from energy-poor inorganic materials in the environment through photosynthesis, and (2)…

Biological psychology, the study of the physiological bases of behaviour. Biological psychology is concerned primarily with the relationship between psychological processes and the underlying physiological events—or, in other words, the mind-body phenomenon. Its focus is the function of the brain

global warming: Carbon dioxide: Another process, the “biological pump,” involves the uptake of dissolved CO2 by marine vegetation and phytoplankton (small free-floating photosynthetic organisms) living in the upper ocean or by other marine organisms that use CO2 to build skeletons and other structures made of calcium carbonate (CaCO3). As these organisms expire…

Regeneration, in biology, the process by which some organisms replace or restore lost or amputated body parts. Organisms differ markedly in their ability to regenerate parts. Some grow a new structure on the stump of the old one. By such regeneration whole organisms may dramatically replace

Antarctica: Biological resources:
Marine resources first attracted people to Antarctica and provided the only basis for commercial activity in this region for many years. More marine resource extraction takes place in the subantarctic and the rest of the Southern Ocean than in the waters of Antarctica’s…

therapeutics: Biological response modifiers:
Biological response modifiers, used to treat cancer, exert their antitumour effects by improving host defense mechanisms against the tumour. They have a direct antiproliferative effect on tumour cells and also enhance the ability of the host to tolerate damage by toxic chemicals…

Biological rhythm, periodic biological fluctuation in an organism that corresponds to, and is in response to, periodic environmental change. Examples of such change include cyclical variations in the relative position of Earth to the Sun and to the Moon and in the immediate effects of such

Allometry, in biology, the change in organisms in relation to proportional changes in body size. An example of allometry can be seen in mammals. Ranging from the mouse to the elephant, as the body gets larger, in general hearts beat more slowly, brains get bigger, bones get proportionally shorter

Biological soil crust, thin layer of living material formed in the uppermost millimetres of soil where soil particles are aggregated by a community of highly specialized organisms. Biological soil crusts are found primarily in open spaces in the dry and extremely cold regions of all continents,

Composting toilet, waterless sewage-treatment system that decomposes human excreta into an inert nitrogen-rich material similar to humus. Because they eliminate the water use associated with typical toilets, composting toilets circumvent the costs associated with traditional sewage treatment.

Biological weapon, any of a number of disease-producing agents—such as bacteria, viruses, rickettsiae, fungi, toxins, or other biological agents—that may be utilized as weapons against humans, animals, or plants. The direct use of infectious agents and poisons against enemy personnel is an ancient

Biological Weapons Convention (BWC), international treaty that bans the use of biological weapons in war and prohibits all development, production, acquisition, stockpiling, or transfer of such weapons. The convention was signed in London, Moscow, and Washington, D.C., on April 10, 1972, and

Biological determinism, the idea that most human characteristics, physical and mental, are determined at conception by hereditary factors passed from parent to offspring. Although all human traits ultimately are based in a material nature (e.g., memorizing a poem involves changing molecular

Biology, study of living things and their vital processes. The field deals with all the physicochemical aspects of life. The modern tendency toward cross-disciplinary research and the unification of scientific knowledge and investigation from different fields has resulted in significant overlap of

Marine biology, the science that deals with animals and plants that live in the sea. It also deals with air-borne and terrestrial organisms that depend directly upon bodies of salt water for food and other necessities of life. In the broadest sense it attempts to describe all vital phenomena

Biology, philosophy of, philosophical speculation about the concepts, methods, and theories of the biological sciences. The sharp increase in understanding of biological processes that has occurred since the mid-20th century has stimulated philosophical interest in biology to an extent

Bioluminescence, emission of light by an organism or by a laboratory biochemical system derived from an organism. It could be the ghostly glow of bacteria on decaying meat or fish, the shimmering radiance of protozoans in tropical seas, or the flickering signals of fireflies. The phenomenon occurs

trophic cascade: Biomanipulation in lakes:
In lakes, trophic cascades are used to improve water quality through biomanipulation, a management practice in which humans intentionally remove whole species from ecosystems. The goal of biomanipulation is to reduce the concentration of harmful phytoplankton, such as toxic blue-green

Biomarker, a measurable and quantifiable biological parameter that serves as an indicator of a particular physiological state. In a medical context, a biomarker is a substance whose detection indicates a particular disease state or a response to a therapeutic intervention. Examples include the

Biomass, the weight or total quantity of living organisms of one animal or plant species (species biomass) or of all the species in a community (community biomass), commonly referred to a unit area or volume of habitat. The weight or quantity of organisms in an area at a given moment is the

materials science: Materials for medicine: These materials, known as biomaterials, include synthetic polymers and, to a lesser extent, biological polymers, metals, and ceramics. Specific applications of biomaterials range from high-volume products such as blood bags, syringes, and needles to more challenging implantable devices designed to augment or replace a diseased human organ. The latter…

Biombo, region located in western Guinea-Bissau. Biombo region surrounds (but does not administratively include) Bissau, the national capital. The regional capital is located at Quinhámel. The western and northern borders of the region are formed by the Mans?a River, which flows east-west and

Jaime Torres Bodet: …employed Japanese verse forms in Biombo (1925; “The Folding Screen”). He was the first editor (1928–31) of Contemporáneos, a cultural and literary magazine influential among Mexican poets.

Biome, the largest geographic biotic unit, a major community of plants and animals with similar life forms and environmental conditions. It includes various communities and is named for the dominant type of vegetation, such as grassland or coniferous forest. Several similar biomes constitute a

biome: Several similar biomes constitute a biome type—for example, the temperate deciduous forest biome type includes the deciduous forest biomes of Asia, Europe, and North America. “Major life zone” is the European phrase for the North American biome concept.

Biomechanics, antirealistic system of dramatic production developed in the Soviet Union in the early 1920s by the avant-garde director Vsevolod Meyerhold. Meyerhold drew on the traditions of the commedia dell’arte and kabuki and on the writings of Edward Gordon Craig for his system, in which the

Biomechanics, in science, the study of biological systems, particularly their structure and function, using methods derived from mechanics, which is concerned with the effects that forces have on the motion of bodies. Ideas and investigations relating to biomechanics date back at least to the

ethics: Abortion, euthanasia, and the value of human life: …with the endpoints of the human life span. The question of whether abortion or the use of human embryos as sources of stem cells can be morally justified was exhaustively discussed in popular contexts, where the answer was often taken to depend directly on the answer to the further question:…

animal disease: Animals in research: the biomedical model:
Although in modern times the practice of veterinary medicine has been separated from that of human medicine, the observations of the physician and the veterinarian continue to add to the common body of medical knowledge. Of the more than 1,200,000 species…

complementary and alternative medicine: Historical perspectives: …care became increasingly centred on biomedicine, and a division of labour proliferated. Some doctors, for example, specialized in surgery, whereas others focused on areas such as infectious disease, human development, or mental health. In addition, beginning in the 19th century, scientists discovered ways to isolate and synthesize the active ingredients…

chemical analysis: Ion-selective electrodes: Biomembrane electrodes are similar in design to gas-sensing electrodes. The outer permeable membrane is used to hold a gel between the two membranes. The gel contains an enzyme that selectively catalyzes the reaction of the analyte. The internal ion-selective electrode is chosen to respond to…

Cambrian Period: Extinction events: …to define biostratigraphic units called biomeres. (Such units are bounded by sudden nonevolutionary changes in the dominant elements of a phylum.) Each of the Cambrian biomere events eliminated several trilobite families, which collectively contained most of the genera and species that were living on the continental shelves. Less attention has…

police: Biometrics:
In criminal investigations biometric analysis, or biometrics, can be used to identify suspects by means of various unique biological markers. Biometric devices can map minutiae in a single fingerprint and then compare it with an exemplar on file, conduct a retinal or iris scan…

police: Biometrics:
In criminal investigations biometric analysis, or biometrics, can be used to identify suspects by means of various unique biological markers. Biometric devices can map minutiae in a single fingerprint and then compare it with an exemplar on file, conduct a retinal or iris scan…

probability and statistics: Biometry:
The English biometric school developed from the work of the polymath Francis Galton, cousin of Charles Darwin. Galton admired Quetelet, but he was critical of the statistician’s obsession with mean values rather than variation. The normal law, as he began to call it, was…

In the burgeoning field of biomimicry, in which engineers, researchers, and architects look to the biological world for the answers to common design problems, 2014 unfolded as a rich year for innovations in robotics, green technology, and medicine. Scientists and engineers officially recognized the

bone: Bone resorption and renewal: …material (osteoid) and its subsequent mineralization. Osteoblasts elaborate matrix as a continuous membrane covering the surface on which they are working at a linear rate that varies with both age and species but which in large adult mammals is on the order of one micron per day. The unmineralized matrix…

Biomolecule, any of numerous substances that are produced by cells and living organisms. Biomolecules have a wide range of sizes and structures and perform a vast array of functions. The four major types of biomolecules are carbohydrates, lipids, nucleic acids, and proteins. Among biomolecules,

Biomonitoring, the measurement of chemical compounds or their metabolites (versions of the compounds that are transformed in the body) in biological specimens. Biomonitoring measurements can be conducted on nonhuman biological samples, such as plants and animals, but use of the term is primarily

Western painting: Fantasy and the irrational: Biomorphic abstraction, in essence the method of Tanguy, extended the resources of Surrealism, and the Chilean Roberto Matta, who began painting in 1938, used it with dramatic effect. A poetic version of the style, rooted in an emotional response to landscape, was evolved in England…

Bion, minor Greek bucolic poet. The Lament for Bion, written by an Italian pupil of the poet, suggests that he lived in Sicily. The 17 surviving fragments of Bion’s Bucolica, mostly concerned with love and only occasionally with bucolic themes, strike a playful, sometimes sententious note. Since

Bion of Borysthenes, Greek philosophical writer and preacher. He was a freed slave and the son of a courtesan and has been credited with originating the Cynic “diatribe,” or popular discourse on morality, whose style may have influenced that of the Christian sermon. Few of his writings

Flavio Biondo, humanist historian of the Renaissance and author of the first history of Italy that developed a chronological scheme providing an embryonic notion of the Middle Ages. Biondo was well educated and trained as a notary before he moved in 1433 to Rome, where he was appointed apostolic

Christina Aguilera: …returned to dance pop with Bionic (2010), though the album was considered a commercial disappointment, as was its follow-up, Lotus (2012). Her 2018 release, Liberation, earned glowing reviews. She later contributed the songs “Haunted Heart” and “Loyal Brave True” to the soundtracks for Addams Family (2019) and Mulan (2020), respectively.…

Bionic eye, electrical prosthesis surgically implanted into a human eye in order to allow for the transduction of light (the change of light from the environment into impulses the brain can process) in people who have sustained severe damage to the retina. The retina is a light-sensitive tissue

The Bionic Woman, American television show, a spin-off of science-fiction thriller The Six Million Dollar Man, about a bionically enhanced secret agent. The show aired for three seasons, first from 1976 to 1977 on the American Broadcasting Company (ABC) network and then from 1977 to 1978 on the

Bionics, science of constructing artificial systems that have some of the characteristics of living systems. Bionics is not a specialized science but an interscience discipline; it may be compared with cybernetics. Bionics and cybernetics have been called the two sides of the same coin. Both use

Ecology, study of the relationships between organisms and their environment. Some of the most pressing problems in human affairs—expanding populations, food scarcities, environmental pollution including global warming, extinctions of plant and animal species, and all the attendant sociological and

pharmaceutical industry: Biopharmaceutical studies:
In addition to the animal toxicity studies outlined above, biopharmaceutical studies are required for all new drugs. The chemical makeup of the drug and the dosage form of the drug to be used in trials must be described. The stability of…

Bj?rk: For the ethereal Biophilia (2011), Bj?rk used tablet computers to help her compose songs, which were released, in addition to conventional formats, as a series of interactive iPhone and iPad apps.

Biophilia hypothesis, idea that humans possess an innate tendency to seek connections with nature and other forms of life. The term biophilia was used by German-born American psychoanalyst Erich Fromm in The Anatomy of Human Destructiveness (1973), which described biophilia as “the passionate love

biophilia hypothesis: Biophilia and technology: Both perspectives were offered in The Biophilia Hypothesis (1993), a work coedited by Wilson and American social ecologist Stephen R. Kellert. Among the collection of views the work presented were those of American biologists Lynn Margulis and Dorion Sagan and Indian ecologist Madhav Gadgil, who considered the possibility that the…

biophilia hypothesis: The human relationship with nature: …nature comes from studies of biophobia (the fear of nature), in which measurable physiological responses are produced upon exposure to an object that is the source of fear, such as a snake or a spider. These responses are the result of evolution in a world in which humans were constantly…

Biophysics, discipline concerned with the application of the principles and methods of physics and the other physical sciences to the solution of biological problems. The relatively recent emergence of biophysics as a scientific discipline may be attributed, in particular, to the spectacular

Vandana Shiva: In her 1997 book, Biopiracy: The Plunder of Nature and Knowledge, she charged that these practices were tantamount to biological theft. Shiva expounded upon her ideas on corporate trade agreements, the exponential decrease in the genetic diversity of crops, and patent law in Stolen Harvest: The Hijacking of the…

Bioplastic, moldable plastic material made up of chemical compounds that are derived from or synthesized by microbes such as bacteria or by genetically modified plants. Unlike traditional plastics, which are derived from petroleum, bioplastics are obtained from renewable resources, and they are

Biopoiesis, a process by which living organisms are thought to develop from nonliving matter, and the basis of a theory on the origin of life on Earth. According to this theory, conditions were such that, at one time in Earth’s history, life was created from nonliving material, probably in the

genetically modified organism: Role of GMOs in environmental management: …microbially produced biodegradable plastic called Biopol (polyhydroxyalkanoate, or PHA). The plastic was made with the use of a GM bacterium, Ralstonia eutropha, to convert glucose and a variety of organic acids into a flexible polymer. GMOs endowed with the bacterially encoded ability to metabolize oil and heavy metals may provide…

bioelectricity: Bioelectric potentials are generated by a variety of biological processes and generally range in strength from one to a few hundred millivolts. In the electric eel, however, currents of one ampere at 600 to 1,000 volts are generated. A brief treatment of bioelectricity follows. For…

Universal grammar, theory proposing that humans possess innate faculties related to the acquisition of language. The definition of universal grammar has evolved considerably since first it was postulated and, moreover, since the 1940s, when it became a specific object of modern linguistic research.

Biopsy, medical diagnostic procedure in which cells or tissues are removed from a patient and examined visually, usually with a microscope. The material for the biopsy may be obtained by several methods and with various instruments, including aspiration through a needle, swabbing with a sponge,

metabolic disease: Disorders of amino acid metabolism: …result from impaired metabolism of biopterin, an essential cofactor in the phenylalanine hydroxylase reaction, may not consistently respond to therapy.

amphibole: Crystal structure: The term biopyribole has been used to describe any mineral that has both I beams and sheetlike structures. The name comes from biotite (mica), pyroxene, and amphibole. Biopyriboles have chain widths and repeat sequences like pyroxenes (single-chain repeats), amphiboles (double-chain repeats), and triple-chain repeats. The latter are…

toxic waste: Cleaning up toxic waste: …be disposed of by using bioremediation processes, in which living organisms are added to the waste to degrade organically or transform contaminants or to reduce them to environmentally safe levels. Some microorganisms use oil as a source of food, producing compounds that can emulsify oil in water and facilitate the…

gall wasp: …larvae of the gall wasp Biorhiza pallida. About 30 such larvae may develop in a single “apple,” or gall. The marble gall, a green or brown growth about 2.5 cm (1 inch) in diameter, is caused by Andricus kollari. The bedeguar gall (also called moss gall, or robin’s pincushion), which…

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