Most philosophical discussion of the particle concept that is afforded by quantum field theory has focused on free systems. This paper is devoted to a systematic investigation of whether the particle concept for free systems can be extended to interacting systems. The possible methods of accomplishing this are considered and all are found unsatisfactory. Therefore, an interacting system cannot be interpreted in terms of particles. As a consequence, quantum field theory does not support the inclusion of particles in our ontology. In contrast to much of the recent discussion on the particle concept derived from quantum field theory, this argument does not rely on the assumption that a particulate entity be localizable.