The tonsilloliths are calcifications that form in the crypts of the tonsil formed by calcium salts or in combination with other minerals and are usually of small size. Some tonsilloliths give the sensation of a foreign object in the throat. They can be a nuisance, but they are not, in general, dangerous. They are one of the causes of halitosis,… Read More »

Know the causes and risk factors of skin cancer or melanoma and its relation to Parkinson’s The research will allow the development of new drugs and therapies against melanoma The skin cancer is one of the most dangerous types of cancer around the world, which is why it is very important the discovery of Argentine researcher Diego Popler… Read More »

Is considered a loss all vaginal bleeding (spotting, or bloody) that occurs independent of the rule and can be irregular or prolonged. The medical term for this fact is to “menorrhagia” and popularly as many names example of “spotting between periods” or “bleeding between periods.” There are many causes that can cause vaginal discharge. In… Read More »

Contents Definition Diagnostic Classification Clinic Anemia Consultation Definition The anemia is a decrease in the concentration of hemoglobin in blood. This parameter is not fixed but depends on several factors such as age, sex and special circumstances such as pregnancy. Diagnostic Criteria According to WHO accepted that there is anemia when the hemoglobin concentration in… Read More »

Human DNA contains genetic information that makes our cells functional entities within a larger whole. The stream of information from DNA to function happens in the form of proteins that anchor themselves to various locations in the DNA and transcribe genetic information into functional cell parts. This process is strictly regulated and is thus very sensitive to change by external factors…

While axillary lymph node evaluation is the standard of care in the surgical management of invasive breast cancer, a benefit has not been demonstrated in ductal carcinoma in situ (DCIS). For women with invasive breast cancer, sentinel lymph node biopsy (SLNB) replaced full axillary lymph node dissection (ALND)…

The findings, which could lead to a new class of cancer drugs, appear in the current issue of ACS Chemical Biology. “These are the first reported small-molecule HuR inhibitors that competitively disrupt HuR-RNA binding and release the RNA, thus blocking HuR function as a tumor-promoting protein,” said Liang Xu, associate professor of molecular biosciences and corresponding author of the paper. The results hold promise for treating a broad array of cancers in people. The researcher said HuR has been detected at high levels in almost every type of cancer tested, including cancers of the colon, prostate, breast, brain, ovaries, pancreas and lung…

The study results, published in the journal Cell, revolve around iPSCs, which since their 2006 discovery have enabled researchers to coax mature (fully differentiated) bodily cells (e.g. skin cells) to become like embryonic stem cells. Such cells are pluripotent, able to become many cell types as they multiply and differentiate to form tissues…

The discovery, published in the journal CELL Reports, provides the experimental evidence for the potential development of a novel combination therapy for HER2-positive breast cancer. The combination includes the FDA approved drug lapatinib and a new experimental drug called a BET bromodomain inhibitor, which works by disrupting the expression of specific genes…

Today, scientists at Cold Spring Harbor Laboratory (CSHL) publish new evidence explaining precisely how the protein encoded by PTEN (called PTEN) works — specifically, how it is recruited to particular locations in our cells where pro-growth signals need to be shut off. The new evidence, assembled by a team led by CSHL Associate Professor Lloyd Trotman, contradicts a long-held assumption about PTEN function, and could help scientists design more effective drugs to counteract cancer’s hallmark trait, uncontrolled cellular growth…