Wilder's nephew said he died late on Sunday at his home in Stamford, Connecticut, having suffered from Alzheimer's disease, the Associated Press reported.

Jordan Walker-Pearlman said Wilder was diagnosed with the disease three years ago, but kept the condition private so as not to disappoint fans.

Mr Walker-Pearlman said: "He simply couldn't bear the idea of one less smile in the world."

Wilder's friend Mel Brooks, who directed The Producers, the classic comedy in which Wilder starred, said on Twitter: "Gene Wilder-One of the truly great talents of our time. He blessed every film we did with his magic & he blessed me with his friendship."

Comedian and presenter Dara O Briain tweeted: " Gene Wilder has died. Sad news, but such a life well lived. For me, Young Frankenstein just pips Wonka, but so many wonderful performances.

"Expecting to hear people were fans of Blazing Saddles, Producers and Stir Crazy, but amazing number going for See No Evil, Hear No Evil."