Caveolin-2 (Phospho-Ser23)

Rabbit Polyclonal Antibody

PRODUCT #: 22-3461

DESCRIPTION: Caveolae are specialize plasma membrane associated organelles that participate in numerous cellular functions including endocytosis, potocytosis, transcytosis, signal transduction and cholesterol trafficking. The major proteins that form caveolae are the caveolins of which there are three major isoforms. Caveolin-2 has been shown to positively regulate caveolin-1-dependent caveolae biogenesis and that this phenomenon is contingent on the phosphorylation of caveolin-2 on serine 23 and 36.

SPECIES CROSS-REACTIVITY:

Hu

APPLICATIONS/DILUTIONS:

WB (0.1 – 0.5 ug/ml)

SOURCE:

Rabbits were immunized with a synthetic peptide based on amino acid residues 18-31 of caveolin-2 phosphorylated on Ser-23.