Brief Summary of ResearchResearch focuses on the neurobiological consequences of exposure to abused substances, including alcohol and stimulants. Brain imaging methods such as quantitative receptor autoradiography and in situ hybridization histochemistry techniques, are combined with genomic analysis to determine mechanisms of action of abused drugs at various transporter and receptor systems. Noninvasive magnetic resonance imaging (MRI) modalities such as high resolution anatomic, magnetic resonance spectroscopic (MRS) and magnetoencephalography (MEG) methodologies are applied in parallel studies to identify the biological and functional correlates that result from repeated drug use.

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