Unlike fully egg-adapted strains that are non-immunogenic, this strain produces satisfactory immunity as determined by neutralization test for antibodies.

Biosafety Level

2

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format

frozen

Storage Conditions

-70°C or colder

Comments

The M41 (Massachusetts [Michigan State University Repository Code 41]) strain is the protype strain of IBV, however it should be noted that antigenicity and virulence of IBV change readily with passage in culture.

Unlike fully egg-adapted strains that are non-immunogenic, this strain produces satisfactory immunity as determined by neutralization test for antibodies.

USDA APHIS VS 16-6 or 16-6A permit must be obtained and a copy of the permit must be sent to ATCC in advance of shipment. The Application Form VS 16-3 (Import controlled material import or transport organisms or vectors) must be submitted to USDA APHIS Veterinary Services to obtain the VS 16-6 or 16-6A permit.

Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.