In Observance of U.S. holiday, Memorial Day, Agilent Cross Lab/ iLab Operations Software will be closed during U.S. hours on Monday May 28th, 2018. EU and APAC support coverage will remain open during this time. We will resume U.S. support hours on Tuesday May 29th, 2018. For urgent matters, please add "Urgent" to the ticket subject and we will prioritize those requests first.

MDACC Proteomics and Metabolomics

Please Acknowledge

In order to continue obtaining Core support in a challenging environment, it is crucial that our users acknowledge the following grants in all publications (see following text). Thank you!

“This work was supported in part by Cancer Prevention Research Institute of Texas (CPRIT) grant number RP130397 and NIH grant number 1S10OD012304-01.”

Overview of Services

Mission. The mission of the Proteomics and Metabolomics Core Facility is to provide the research community with cutting-edge expertise and services for sensitive, precise, and accurate measurement of proteins and metabolites using mass spectrometry-based technologies.

SERVICES

Proteomics:

Protein Identification: High sensitivity (silver stain OK), up to 100 proteins or more may be indentifiable.

Molecular Weight Determination:Check the MW of your peptide or molecule. Proteins may be measured if enough clean protein is available (larger proteins are less reliable).

Mechanism of Action Studies: Assistance with pharmacological experiments to determine an agent's mechanism of action by integrating pharmacological endpoints (e.g., cell viability) with metabolomic and other omic data.

Sample Preparation Assistance: Assistance with or full-service provision of sample preparation. For example, you can ship cells and treatment(s), we can work together to design an experiment, and we can conduct the entire experiment.

Drug Combination Analysis: We have developed software for conducting 3-D response surface and response envelope analyses of drug combinations for the statistical determination of synergy, additivity, or antagonism. (Please contact Phil Lorenzi to discuss)