The
following is a transcript of an address given to the American Pediatric Society
at the conclusion of its annual convention in Boca Raton, Florida, last week.
The keynote speaker, noted pediatric pharmacologist Dr. Matthew C. Taibbi, addresses
recent revelations about the effects of antidepressants on minor children.

LADIES
AND gentlemen. I thank you for the honor of making me your keynote speaker this
year. I am sorry only that I had to spend so much time preparing this speech,
while the rest of you worked on your tans. It doesn't seem fair that I should
be the only ugly one.

(Laughter)

Well,
okay, that Dr. Lowenstein and I should be the only ugly ones.

(More
laughter)

Just
kidding, Sidney. You know I'm just bitter because Marion chose you. God, what
a fox. Stand up, Marion. There we go. Ladies and gentlemen, Dr. Marion Lowenstein!

(Applause)

Thank
you. What a gorgeous couple. We all love you both. We love your work. Thank
you.

Now.
To business. Ladies and gentlemen, my dear colleagues of the pediatric sciences,
we stand today at a crossroads. Earlier this week, I was briefly sober enough
to hear it reported on the news that the Food and Drug Administration has, in
its infinite wisdom, elected to release the results of studies that apparently
"demonstrate" that some antidepressants cause suicidal thoughts in
children. Can I get a "Like, WHATEVER!"

(The
crowd answers: "Like, WHATEVER!")

Thank
you. Now, as most of you are aware, the prescription of selective serotonin
reuptake inhibitor drugs for adolescent and pre-adolescent depression has been
standard practice for about Christ, I want to say five years, but maybe
it's only three. Is it three, Sidney? He's nodding. Nodding, and now, he's holding
up three fingers-that's what I thought, too. Three fingers, right, Sidney? Well,
whatever it is, in the last few years we've been handing that shit out like
candy, we all know that.

In
fact, some tourist in the hotel bar this morning was telling me that in 2002
alone we wrote something like 11 million antidepressant prescriptions for children.
And she sounded like she knew what she was talking about. Her husband is some
hot-shit architect in northern Virginia, makes millions. But he's away on business
a lot and has a little problem with the ol' ED, if you know what I mean. And
this still-young woman is all alone in the hotel this week, ladies and gentlemen.
In fact, I'm going to go upstairs and visit her just as soon as we finish here.

In
any case, this decision by the FDA is going to force all of us to reexamine
everything we think we know about this particular line of pharmaceuticals. Now,
I personally have been eating them by the fistful since before they were even
approved for use. In my experience, they just give you a slight buzz, like coffee.
(Reaches into pocket, takes small handful of pills, shoves four or five in mouth.)
The best, if you can get them (chews), are Wellbutrin, because they give you
that creepy awake look in your eyes that will make your friends wonder what
you're on, make you look like the villain in a karate movie. Plus they significantly
delay ejaculation, especially if you mix them with hard alcohol.

It
is hard to say just what effect these drugs would have when administered in
a normal course of treatment, but I have to think that if kids are having suicidal
thoughts after taking them, it might very well be that they are not taking enough
of them, not mixing them with hard alcohol, and not knowing enough to chase
the crashes with valium or vicodin or even, in a pinch, a whole bottle of Ibuprofen.

Children
are weird. We just don't know enough about the brains of children. Every now
and then I'll get a kid in my office, and I'll be like, "So what's the
deal? What's eating you?" And instead of answering, the kid will just stare
glumly down at the floor and trace a circle on the ground with his or her toe,
which he/she has to stretch out just to reach the floor. (It's just flat-out
crazy how small children are, incidentally. That always boggles my mind.) And
I'll snap my fingers and say to the kid, "Hey! You there! Look alive! What
the fuck is the matter with you?" And he'll just cringe even more, like
that's going to make me go away somehow.

They're
just totally unrealistic that way. And if he remains unresponsive, sometimes
I'll get up from my desk, go stand right in front of him, and just drop my pants.
"How about this?" I say. "Does this interest you? Is this what
you want?" Again: no reaction. At best, no reaction. So from there I usually
just go straight to the prescription tablet, because that's what the book says
to do.

Sometimes
if you take a child's head and just squeeze it really hard, he will stop talking
for like four or five minutes, and they get this amazing look on their faces,
like they've just seen something startling. You have to sneak around right behind
the child and place your palms on the sides of his head, and just squeeze like
hell. I've been doing this for about four, maybe five years. Now, when kids
come into my office, the first thing they do is back up against a wall. They
can be smart like that. That's one of the things you notice after a while.

Sometimes
a parent will come in to my office and say to me something like, "Why is
my child depressed?" And I'll say, "What do you mean, depressed? Isn't
he taking the drug?" And they're like, yeah, he's taking the drug, but
he's still depressed. He cries all the time and the kids at school kick his
ass every day. And I'll say, well, give him more of the drug, then. And they're
like, we gave him more of the drug. And he just cried more and the kids at school
kicked his ass even more. And I'll say, well, maybe the kid's just a loser.
And the parents will be like, yeah, that's what we thought. We just wanted to
make sure.

Once
I got a referral from a school board. They bring me this kid and they're like,
"We think this kid has ADHD." And I'm like, "Oh, yeah? Why do
you think that?" And they say, "Well, for one thing, he doesn't pay
attention in class." So I'm thinking to myself-class? What do they mean?
"What do you mean, class?" I say. "What kind of class?"
And they say, "Well, you know, English, history, earth science." "No
kidding," I say. "What does he learn in history class?" "Well,"
they say, "he learns about the Stamp Act, the Continental Congress and
the American Revolution." "That's amazing," I say, shaking my
head. "The American Revolution. Amazing." Then I take the kid and
I just start shoving Ritalin pills in his mouth.

Can
you imagine, ladies and gentlemen-history class! There are so many things we
just don't know.

The
point I'm trying to make is that children are a completely different world,
and always will be. Will the FDA ruling affect our profession? Can I get a,
"What FDA ruling?"

(Crowd
answers: "What FDA ruling?")

Exactly,
what FDA ruling? We've forgotten already! Now let's go get a drink!