News

Pharmacological Effects of Sulfathiazole

Author:Ray Dean

Source:www.oceanchinachem.com

Release on :2016-07-18

Sulfathiazolebelong to sulfa antibiotic, little absorption after oral
administration, a slow decomposition in the intestine Sulfathiazole exert its
strong antimicrobial effect, the goods against Gram-positive and negative
bacteria have antibacterial effect, but the bacteria resistance to the drugs
phenomenon in general, bacteria and other Enterobacteriaceae increased its
drug-resistant strains.

Meanwhile,
the product is a broad-spectrum antibacterial agent, its mechanism of action is
similar in structure to the amino acid (PABA), PABA with competitive effect on
in vivo bacterial dihydrofolate synthetase, thereby preventing bacterial
synthesized as PABA required folic acid, reduces the amount of metabolically
active folate, which is a bacterial synthesis of purine, thymidylate and
deoxyribonucleic acid (DNA) of the necessary material, thereby inhibiting
bacterial growth and reproduction.

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