This paper explores domestic mergers and acquisitions (M&As) from the regional perspective. The Finnish evidence reveals that geographical closeness is a characteristic of great importance for domestic M&As. Thus, a great number of M&As occur within narrowly defined regions. Interestingly, domestic M&As reinforce the core-periphery dimension. The results from the matched firm-level data show that larger companies can overcome geographical boundaries more easily and domestic M&As are more likely to occur in regions that contain a great number of companies. In addition, the results reveal that a strong ability by an acquiring company to monitor the target ( measured by the knowledge embodied in human capital or in research and development stock) can support M&As that occur across distant locations.