Studies

No randomized controlled trials of antibiotic prophylaxis for endocarditis have been performed

The AHA guidelines in 2007 recommended cessation of prophylaxis in moderate-risk patients, and the NICE guidelines in 2008 recommended cessation of all prophylaxis

A number of observational studies have compared endocarditis incidence rates between time periods before the new guidelines to time periods after. In the U.S., these studies have found no increased
incidence of endocarditis. In the U.K. where the NICE guidelines are typically followed, studies have been mixed. The most recent study that spanned 5 years post-NICE guidelines found a
significant increase in the incidence of endocarditis in the U.K. [PMID 25467569]

Orthopedic implant infection prophylaxis for dental procedures

In 2017, the AAOS published guidelines for infection prophylaxis in patients with orthopedic implants who were undergoing dental procedures

The information is available on a webpage that makes a recommendation based on patient characteristics that are entered in a form

Occupational exposure

The University of California at San Francisco provides free, rapid expert consultation and advice on management of occupational HIV, Hepatitis C, and Hepatitis B exposure.
They can be contacted by phone or email at this link - UCSF website.