Background N,N-di-n-propyl-2-[2-(4-[11C]methoxyphenyl)-6,8-dichloroimidazol[1,2-a]pyridine-3-yl]acetamide ([11C]CB184) is a novel selective radioligand for the 18-kD translocator protein (TSPO), which is upregulated in activated microglia in the brain, and may be useful in positron emission tomography (PET). We examined the safety, radiation dosimetry, and initial brain imaging...

Small-scale hydroelectric power generation has recently attracted considerable attention. The authors previously proposed an undershot cross-flow water turbine with a very low head suitable for application to open channels. The water turbine was of a cross-flow type and could be used in open channels with the undershot method, remarkably simplifying its design by eliminating...

Objective We report synthesis of two carbon-11 labeled imidazopyridines TSPO ligands, [11C]CB184 and [11C]CB190, for PET imaging of inflammatory process along with neurodegeneration, ischemia or brain tumor. Biodistribution of these compounds was compared with that of [11C]CB148 and [11C](R)-PK11195. Methods Both [11C]CB184 and [11C]CB190 having 11C-methoxyl group on an aromatic...