Studies conducted in the USA and Brazil involved the analysis of
phenotypic characters, Agronomic characteristics (items 2.2.1 to
2.2.5, ANNEX IV of the process), nutrient composition (item 3.1 to
3.2, Annex III to the file), the effect of DAS-44406-6 soybean on
chemical and Physical properties of the soil (item 9, Annex IV of
the process), the organic matter degradability of Plants (item 10,
Annex IV of the process) and the effect of the transgenic plants in
the state Nutritional value of plants (item 9.2., Annex IV of the
process). In all these studies, no No statistically significant
difference was detected between soybean DAS-44406-6 and its
Conventional control of the same genetic background, which could
indicate the occurrence of Interactions of genes inserted in
soybean DAS-44406-6 and other genes of the genome with Of
detectable pleiotropic and epistatic effects, with genetically
modified soya remaining
With the same phenotype as the conventional one, except for the
inserted characteristic.
The various studies that represent this risk analysis, associated
to the large number of
Of evaluated characteristics, allows to conclude that no evidence
of pleiotropic effect or
Associated with the inserted genes was observed.

Likelihood that the potential adverse effects will be realized

The PAT proteins, AAD-12 and 2mEPSPS, present in the gene construct
of the event
DAS-44406-6, have specific action under their respective
substrates. The observations in
Several generations of soybean DAS-44406-6 show that the presence
of the aad-12, 2mepsps and
Pat did not produce changes in host plant characteristics,
including characteristics Agronomic and reproductive, indicating
the absence of interactions between these genes

Possible consequences:

The studies carried out in Brazil and the United States showed that
soybean DAS-
44406-6 does not differ from conventional soybean in agronomic,
morphological,
Reproductive characteristics, survival characteristics and the
dissemination of
Response to major pathogens and pests, with the exception of
Herbicide tolerance characteristics; Thus, there is no additional
risk to the use of this soybean in relation to conventional
soybeans

Estimation of the overall risk

The phenotypic and plant growth characteristics that respond to
the
Stress, response to insect pressure and disease in
And the characteristics of soybean germination and dormancy
DAS-44406-6 were not
Were altered relative to conventional soybean control. Therefore,
these data
Conclusion that agronomic characteristics, and susceptibility to
soybean diseases and pests
DAS-44406-6 are not significantly different from those of control
soybeans and nothing indicates that soybeans DAS-44406-6 may pose a
significant risk to the environment other than the risks May occur
with the conventional soybean itself.

Recommendation(s)

There is no experimental evidence that soybean DAS-44406-6 is lower
or has any
Toxicological or nutritional risk to animals which is distinct from
the conventional variety
Widely used. Therefore, the modification introduced by genetic
manipulation,
Simply conferred resistance to the herbicides glufosinate ammonium,
glyphosate and 2,4-D,
Providing agronomic, economic and ecological advantages

Need(s) for further information on specific issues of concern

As established in art. 1 of Law 11,460, of March 21, 2007, "are
prohibited the research and the cultivation of genetically modified
organisms in the indigenous lands and
conseration unidts ", except in the areas of environmental
protection

Receiving environment(s) considered

Soy is not native to Brazil and there is no native, wild or feral
species in the country that can cross-link with Glycine max.
Therefore, there are no additional risks for the environment
Environment with soybean planting DAS-44406-6 in addition to those
already caused for the different conventional soybean varieties in
use in the country