Previous GeneCards Identifiers for KRTAP11-1 Gene

Summaries for KRTAP11-1 Gene

GeneCards Summary for KRTAP11-1 Gene

KRTAP11-1 (Keratin Associated Protein 11-1) is a Protein Coding gene.
Diseases associated with KRTAP11-1 include monilethrix and pachyonychia congenita.
Among its related pathways are Metabolism and Metabolism.
GO annotations related to this gene include structural molecule activity.

UniProtKB/Swiss-Prot for KRTAP11-1 Gene

In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

Graphical View of Domain Structure for InterPro Entry

UniProtKB/Swiss-Prot:

Function for KRTAP11-1 Gene

Molecular function for KRTAP11-1 Gene

UniProtKB/Swiss-Prot Function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins