Project: Evaluation of the (11C)methoxyprogabidic acid binding in the brain of patients with complex partial seizures by Positron Emission Tomography (PET).

project duration

01-JAN-96 – 31-DEC-99

abstract

Preliminary studies with (11C)methoxyprogabidic acid showed in normal individuals a selective binding in the hippocampal regions and in the temporal neocortex. The aim is to determine if (11C)methoxyprogabidic acid as GABA tracer is useful for the location of the epileptic focus in complex partial seizures by selective loss of the receptor binding in one hippocampus.