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Oral cancer is a major problem in India and accounts for 50% -70% of all cancers diagnosed as compared to 2-3% in UK and USA, it is due to certain personal habits of our population, like tobacco chewing and smoking. Oral exfoliative cytology seems to offer a good method of screening of the population with suspicious lesions of oral premalignant and malignant conditions. The oral cytology is simple and out patients department procedure with a high accuracy. It can be useful for surgeons, physician and dentist when one hesitate to perform an invasive procedure, like a biopsy, or desire more information regarding a lesion before referring the patients to the higher center. Oral cytology can also be used for the ancillary testing like molecular study, flow cytometery and immunocytochemistry. This book provides wide knowledge on the procedure and applicability of the oral exfoliative cytology which will be beneficial for Pathologists, General Physicians, Surgeons, and Dentists.