Biochips is a functional unit, which has an ability to perform multiple works parallelly. Tissue chips are similar as biochips which works as an alternate for tissue to enable the organ function normally. These biochips and tissue chips play a major role in the field of tissue engineering. Micro arrays which has its application over the micromechanical studies, has a 2D grid system which has a solid substrate of positively charges like silicon or glass. They perform a best role in signal transduction studies