Differs from Heterosalenia in having polyporous adoral ambulacral plating, slightly more rudimentary perforation of interambulacral tubercles and adapical interambulacral plates that lack a primary tubercle. Distinguished from Novasalenia, which also lacks aboral interambulacral tubercles, by its aboral trigeminate plate compounding; Novasalenia has strictly bigeminate plating.

Vadet (1999, p. 78) made Polysalenia the type of the family Pseudosaleniidae, and included here also Prosalenia and Heterosalenia. This encompassed all salenioids with a single suranal plate and perforate tubercles, a grade taxon.