Priceline's Longtime CEO Hands Over Reins

Priceline.com Inc. replaced its longtime chief executive with the boss of its most profitable hotel-booking unit, ending an 11-year tenure that oversaw one of the most dramatic turnarounds of the past decade.

Chief Executive Jeffery Boyd, 56 years old, said he would hand the reins of the online travel company to Darren Huston, 47, a former Microsoft Corp. executive who has been running its Booking B.V. unit since 2011. Mr. Boyd will...