Welcome to the third edition of Viewpoints, our monthly e-newsletter. Our
guiding objective is to support you in achieving a healthy lifestyle through
knowledge. An understanding of how our bodies work is the foundation for
changing our behavior, reversing Insulin Resistance and its related conditions,
losing weight and, essentially, feeling your best.

In this issue we focus on research that shows, increasingly, that Insulin
Resistance is the basis for a number of serious health conditions. It is,
simply, an “under” disease - underdiscussed, underrecognized, underdiagnosed and
undertreated.

Knowledge is power and Insulite Laboratories is here to help.

“Nothing is a waste of time if you use the experience wisely.”

- Auguste Rodin, sculptor

Even a setback can be put to good use.

INTELLIGENCE REPORT

Syndrome X Heart Risks
Reduced by Exercise and Weight Loss

Working off extra pounds can do wonders for the health of those suffering from
Syndrome X, which consists of a collection of metabolic abnormalities that put
sufferers at risk of a stroke or coronary heart disease. Recent research shows
that a combination of exercise and weight loss greatly reduces the dangers of
two factors: insulin overproduction and high blood pressure.

An estimated 40 million Americans have Syndrome X. Doctors often overlook the
condition, also known as Metabolic Syndrome. These syndromes are characterized
by elevated levels of cholesterol and triglycerides, obesity and Insulin
Resistance.

A study by Duke Medical Center found that overweight people with Syndrome X, who
made lifestyle modifications by exercising and losing weight, had a 47%
reduction in insulin overproduction, also called hyperinsulinemia. Patients who
exercised but didn’t lose weight had a 27% reduction. The patients who achieved
the greatest weight loss showed the most significant improvements in abnormal
insulin responses.

Lana Watkins, the study’s lead author, wrote: “A non-pharmacologic treatment
for these patients is needed, since drugs prescribed to lower blood pressure
have been shown to actually worsen carbohydrate and lipid metabolism in
Syndrome X patients, negating the beneficial effects of those drugs.

“In the last five years there has been an increased appreciation that
hyperinsulinemia is an independent risk factor for mortality and it can
even be seen as a marker or mechanism underlying this increased risk.”

The relationship between obesity and cancer grows ever more disturbing. A report
from the National Cancer Institute states that obesity appears to increase the
chance of breast cancer in postmenopausal women. It also highlights the link
between obesity and cancer of the colon, prostate, endometrium (the lining of
the uterus), cervix, ovary, kidney and gallbladder.

This is particularly bad news in light of the fact that more than half of adult
Americans are now overweight to some extent. Obesity is defined as someone
having greater than 50% body fat.

Although there are many theories for how obesity increases cancer risk, the
exact mechanism is not yet known. But one-in-five health dollars is now spent on
trying to counter the obesity epidemic, which has been growing for 30 years and
shows no sign of going into reverse. One of the cornerstones of this epidemic is
Insulin Resistance, with greater consumption of carbohydrates setting the stage
for the onset of the condition.

SOURCE: National Cancer Institute: Cancer Facts, September 2001

DR. MARY'S VIEW:

“Reducing insulin levels may impact the formation of cancer.”

Cancer has never more visible in the news than it is today. Many people are fearful of receiving a cancer diagnosis, yet most do not know how to reduce their risk of getting the disease.

While the conclusions about weight loss and cancer reduction are not clearly drawn, additional research concludes that insulin levels are a factor in the growth of cancer cells in a laboratory setting. It does, therefore, seem logical to conclude that reducing a person’s insulin levels may impact the formation of cancer.

The reduction of insulin production is also critical for weight loss as well as reversing Polycystic Ovarian Syndrome (PCOS), cardiovascular disease and high blood pressure.

Fact:
There is little evidence to support this assertion. In fact, research has
shown that the more protein you consume, the better your cardiovascular disease
profile is, the leaner, more metabolically active body mass you have, plus
better sugar stabilization.

Unless someone suffers from kidney impairment, diets that emphasize protein are
healthier than eating habits based on carbohydrate consumption.

CONSULT DR. MARY

Q. Do carb-blockers really work?

A. Carb-blocker diet pills claim that you can lose weight without
changing your diet. The pills work by inhibiting the metabolism of carbohydrates
into stored fat. But there are no clinical studies performed by mainstream
medical and research communities to suggest they work in the long-term. As we
know, gradual weight loss is far more likely to be permanent.

The critical ingredient of these products is called phaselous vulgaris, an
extract from the northern white kidney bean. This extract interferes with an
enzyme in the body called alpha-amylase that breaks down carbohydrates into
glucose. Instead of carbohydrates being broken down and turning to fat, the
carbs are excreted from the body before they can enter the bloodstream.

Even though the action mechanism for this product is clear, the effectiveness
has not yet been determined. There is no evidence that people are actually
losing weight.

“I have reduced my waist size considerably after only 5 months on the
Insulite System. At age 67, I look and feel great and have recommended Insulite
to my daughter. Our entire family has benefited from the carbohydrate reduction
guidelines in your Nutritional Plan.”

RS
Madison, Wisconsin

DID YOU KNOW?

INSULIN RESISTANCE UNDERLIES PCOS

The association between Polycystic Ovarian Syndrome (PCOS) and Insulin
Resistance is well-known. Obesity is a major cause of PCOS and Insulin
Resistance is an underlying factor in obesity. PCOS is an imbalance of hormones
linked with the way the body processes insulin. Women who suffer from the
syndrome are at far higher risk of developing breast cancer, Type 2 Diabetes,
hypertension and cardiovascular disease.

Reversing Insulin Resistance, and thereby balancing hormones is vital
for combating PCOS which also causes menstrual irregularities and
infertility.

“You may have to fight a battle more than once to win it.”

Margaret Thatcher.

Try, try and, if necessary, try again until you accomplish your goals

INSULITE LIFESTYLE: TIPS

Losing weight is a gradual process and best undertaken step-by-step. The
underlying science behind behavioral change indicates that your brain must
habituate or normalize to these changes – a slow and strategic transition is
best.

WEANING YOURSELF OFF PASTA is much easier than it sounds! If these tempting but
high-carb noodles form the centerpiece of your meal, you can opt for the whole
wheat variety now widely available, as well as slowly introduce healthy elements
into the mix.

We suggest using olive oil in lieu of creamy sauces, by gently sautéing chopped
garlic and green onions or shallots and fresh herbs like oregano and basil. To
further enrich and thicken your sauce, add chopped tomatoes. (Skins are easily
removed by placing the tomatoes in just-boiled water for three minutes.)

You can slowly reduce the pasta portion of the meal by incorporating some of
your favorite vegetables such as chopped, cooked spinach, broccoli, cauliflower,
zucchini or others into the pasta. Remember, steaming vegetables is best! For
some crunch, try adding a handful of sliced nuts that have been roasted at 400
degrees for 7-10 minutes on a baking sheet with non-stick spray. Or add some
small pieces of turkey breast, fish, steak or hamburger that have been broiled
or grilled.