Anti Ox - Glucoraphanin and Curcumin

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This product is a unique combination
of phytonutrients designed to enhance antioxidant potential by
stimulating nuclear factor-erythroid-2-related factor 2 (Nrf2), a
dynamic pathway known to increase the production of the body’s most
important cellular antioxidants. This unique combination of truebroc™,
turmeric, pterostilbene, and resveratrol provides potent free radical
scavenging potential, balancing of key inflammatory associated pathways,
and induction of intracellular antioxidant production. These powerful
phytochemicals are the basis of many “superfoods” and have extensive,
peer-reviewed research supporting their dramatic effect on cell health
and longevity.

Overview:

Nrf2 is a transcription factor that
regulates the antioxidant response of the body.1 It is the primary
cellular defense against the cytotoxic effects of oxidative stress.2
This key protein is found inside a cell and is inactive until it is
released by an Nrf2 activator. Once activated, Nrf2 migrates into the
nucleus and binds to DNA at the location of the master antioxidant
regulator, the antioxidant response element (ARE).3 Studies suggest Nrf2
plays an important role in supporting the activation of cellular
antioxidant systems, as well as inflammatory balance.4,5 A number of
fruit and vegetable compounds have been shown to activate Nrf2 and ARE,
and increase antioxidant potential.6-9 It is believed that these
compounds have a protective effect on the body, help maintain a healthy
cycle of inflammation, and induce cellular longevity.10

Broccoli Seed Extract†

Broccoli seed extract has the
highest levels of glucoraphanin (a potent Nrf2 stimulator) of any
broccoli product available.11 In fact, 230 mg of broccoli seed extract
is equivalent to consuming 1 ¼ cups of fresh broccoli. Glucoraphanin is a
phytochemical compound that acts as the precursor to sulforaphane, one
of the leading compounds in broccoli that is responsible for many of its
positive benefits.12,13 These compounds and their mechanisms have been
studied extensively and supported by more than 500 scientific
publications. Glucoraphanin and sulforaphane act as direct activators of
Nrf2 and potent antioxidants shown to support detoxification and
inflammatory balance.14-18 Studies show they work by improving hormone
balance and increasing functional enzymes that support excretion of
toxins from the body.19 Broccoli seed extract has been shown to remain
active within the body for up to three days following consumption.20

Turmeric Root Extract

† Turmeric is a bright orange-colored
spice used for thousands of years in cooking and medicine. Through its
antioxidant mechanisms, the active ingredient in turmeric, curcumin,
helps to maintain a healthy cardiovascular system, support
gastrointestinal (GI) health, and provide neuroprotective activity.21-24
Curcumin has been shown to play a crucial role in maintaining proper
inflammatory balance in a variety of bodily systems due to its ability
to modulate Nrf2.25 Studies have shown curcumin supports the maintenance
of balanced inflammation in endothelial cells and cardiac cells.26-28
Curcumin has also been found to provide antioxidant protection to the
cardiovascular system by reducing oxidative stress and supporting a
normal immune response.29

Pterostilbene†

Stilbenes make up a subgroup of
phytochemicals that have potent antioxidant properties. Pterostilbene is
a specific stilbene found in plant varieties like deerberry, rabbiteye
blueberries, unripe pinot noir grapes, Botrytis vinifera-infected
Chardonnay grapes and Xarello grapes. Through activation of Nrf2, in
vitro studies show pterostilbene significantly enhances expression of
antioxidant enzymes, such as heme oxygenase-1 (HO-1) and glutathione
reductase (GR).30-33 Some studies have shown antioxidant benefits may be
improved when pterostilbene is combined with curcumin and
resveratrol.34, 35

Resveratrol

Resveratrol, like pterostilbene, is a
stilbene found in many plants and red wines. It is the most
well-researched stilbene. Studies of resveratrol have found it to
enhance the potential of antioxidant and detoxification activity through
Nrf2 activation.36 Other studies have linked resveratrol to enhancing
blood sugar balance, balancing inflammation and reducing oxidative
stress.37, 38

Directions 2 capsules per day or as recommended by your health care professional.