MyD88 polyclonal antibody

Product Specification

Synthetic peptide corresponding to a portion of human MyD88. The sequence is completely conserved in mouse.

UniProt ID:

Q99836

GenBank ID:

NM_002468.1 (RefSeq)

Species reactivity:

Human, Mouse, Rat

Applications:

WB

Recommended Dilutions/Conditions:

Western Blot (1-2µg/ml, ECL)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.

Application Notes:

Detects a band of ~35kDa by Western blot.

Purity Detail:

Peptide affinity purified.

Formulation:

Liquid. In PBS containing 0.02% sodium azide.

Shipping:

Blue Ice Not Frozen

Long Term Storage:

+4°C

Scientific Background:

MyD88 (Myeloid differentiation primary response gene 88) is a general adapter protein for the Toll/IL-1R family of receptors that have been shown to induce growth arrest, terminal differentiation, and apoptosis. MyD88 plays an important role in the inflammatory response induced by cytokines, IL-1 and IL-18, and endotoxin. It has been shown that signaling via MyD88 is essential for an LPS response. MyD88 is a cytoplasmic protein, which is expressed in many tissues.

Western blot analysis of MyD88 in Jurkat whole cell lysate with MyD88 antibody at 1:500 dilution.