Occupation: Second Lady and College ProfessorAge: 59Residence: Washington, D.C.

It was a charity race that got you started running, wasn't it?I started running after Joe and I were asked to kick off a Komen Race for the Cure in the early '90s. After sounding the horn, we ran to get out of everyone's way, and I got so winded that I said, "I'm going to start running." My first run was around my neighborhood in Delaware—about a third of a mile. I kept increasing the distance until I got the bug.

What did you like about it? It was such a feeling of freedom. I love running outside. It was a good feeling. I mean, I felt good about myself, and so that's why I continued. I started when I was, what, 40, so I've been running almost 20 years. And I've been pretty consistent with it. I mean, I've had things in my life happen where I've had to slow down a little bit, but I've always gone back to it.

How many Susan G. Komen races have you participated in? Oh, I'm not sure about the exact number—probably a handful or so. Over the years I've also completed several 5-K, 10-K, and half-marathon races for other cancer charities.

Why are you participating in the Komen race this year? This year, I am serving as the Honorary Chair for the Washington D.C. Race for the Cure along with Joe. It's the second year in a row we've done this, and we are honored to continue the tradition. On the eve of race day, Joe and I will host breast-cancer survivors for a special reception at our home. It's a really special event and gives us a chance to spend time with survivors and their loved ones before the race. We're really looking forward to it.

In addition to your work with Susan G. Komen Race for a Cure, you've been very involved in breast-cancer awareness. Why is it such an important issue for you?Back in the early '90s, I had several friends who got breast cancer. One died. I felt like I had to do something, and I couldn't just sit by. Being an educator, I thought, Well, maybe there's something I could do in education. So I started the Biden Breast Health Initiative, and I have health-care professionals go to high schools in Delaware, and we talk to them about good health practices, breast self-examination, and early detection. So not only is that awareness created for them, but they take that message home to their moms and grandmoms, and they start a dialogue. We've reached more than 10,000 young women.

What's typical for a daily workout? Where do you usually run and how many miles? Well, you know, my goal is five miles at a nine- to 10-minute pace five days a week. But between teaching and administration responsibilities, I barely make that any more. Like, for instance, this morning I had a breast-cancer event here [at the house, the Vice President's Residence at the United States Naval Observatory in Washington, D.C.] at breakfast. I knew I was limited for time, so I did a little over four miles on the treadmill. I try to adapt my workout to where I am—I could be in another city or country—so it often depends on what I'm doing. I also try to incorporate a little bit of weight training, because I think that's really good for your bones. That's my basic workout.

How do you change your training when you're preparing for a race, as you are now? When I've done races, I've been pretty disciplined about setting up a plan for myself and then following that plan on a daily basis. That's how I got ready for the 1998 Marine Corps Marathon, which is the only one I've done. I've done several half-marathons and 10-mile races. In the next couple months, I would love to train for the Army 10-Miler [in Washington, D.C.], and so I feel like I could work up to that.

You're pretty close to the race in the beginning of June, so what are you aiming for now? Are you still doing five miles or are you trying to ramp it up? Usually because of time, I can't go over five miles—sometimes maybe I could do six or seven, and sometimes I could just do three. Because, you know, my days are pretty filled, so I have to run in the morning or whenever I have time, and then I've got to build in that time to get back and showered and changed and read my briefing for an event. I have to factor all of those things in.

So what's your best time? My best time was my only time [the Marine Corps Marathon]. I finished in 4:30:32. My goal was 4:30, so I feel like I met that goal and I was ecstatic. I have to say it was one of the highlights of my life. I saw my family at several spots along the way. And I tell you, at the end of that race, I felt like I could run five more miles. My adrenaline was through the roof.

Would you consider running another marathon?I always said I only wanted to do one marathon, but I've also learned to never say never!

So now do you run with the Secret Service?Oh, yeah. That's another big change in my life now—I usually have someone ahead of me and someone behind me. But they've been great. I just say to them, "I need to pretend you're not here," because I love to run by myself, and they're pretty respectful of that.

Are the Secret Service in cars or are they actually running?No, these guys are runners. I mean, these guys are fit, and they're good runners.

You said you love to run by yourself. Why is that? Is it because you use that time to think or is it meditative for you?I think that running creates a sense of balance in my life. And it really calms me down. It's a great feeling to just get out and lose myself in a run. I think that's why I continue to run because, as you know, once you get that, you kind of crave that time for yourself.

So I guess you don't exercise with your husband?Sometimes Joe runs with me, but he's not a runner. He's an athlete, and he does a lot of exercise. Like last night, he was playing football out on the front lawn with our granddaughter who loves to play football. So he likes to do a lot of sports, but I think once you're a runner, you really stick with it.

But I have heard you do run with some of your staff.A lot of people on my staff run, so that's nice. If we get time and we're in a different city, we'll go out and do a run.

Obviously this is a very fit administration. Is it motivating? The President and First Lady are known for it. Do you ever run with either the President or First Lady?You know, I really love what Michelle is doing with Let's Move! Let's face it, we really did need something like this in this country to fight childhood obesity. I see Michelle at events or we pass one another on the way to meetings, but life is a little too hectic. I mean, that would be great, but it just isn't reality that we would have time to do that.

So do you feel more pressure to perform well as a runner now that everyone knows you?Well, when I'm out running, people don't recognize me, which is great. I don't feel pressure; I'm not out to beat anybody or hit a certain time. I just do it for the enjoyment of it. I'm doing it for myself.

How do you make the time to run? How do you carve that time out?Well, I definitely make it a priority. That's not always possible, but my office knows that it goes first on the list. It's really an important part of my life, and I try to be pretty true to it.

Do you have a preferred workout outfit?I don't have a workout outfit. The usual, you know, black pants and a T-shirt.

Do you listen to music when you run?Oh, yeah, I do.

Can I ask what's on your iPod?What's on my iPod? Well, certainly Bruce Springsteen. [Biden was born in New Jersey.] I don't know what else. My kids are runners, by the way. I have two sons and a daughter and two daughters-in-law, and they're triathletes, my two sons and their wives. So if they hear something good, they'll say, "Oh, Mom, let me put this on your iPod."