A recent study reported deposits of a protein, alpha-synuclein, in the synapses of dementia with Lewy bodies patients. The researchers believe it may be this protein that is responsible for the dementia symptoms and the progression of DLB in the brain.

In the quest to cross the BBB, researchers have developed immunoliposomes targeted to BBB receptors and α-synuclein that could potentially enable the transport of drugs to reach one of the drug targets in Parkinson’s disease.