Dynamical studies of protein carriers

Molecular Links Rome (MoLiRom s.r.l.) is a spin-off Company of the “Sapienza” University of Rome. The mission of MoLiRom is focused on the development of advanced projects in the biosynthesis and production of protein based products including protein engineering based on random or site directed mutagenesis. The development of diagnostic and therapeutic nanodevices based on engineered recombinant proteins capable of recognizing specific tumor cell receptors is currently actively pursued. Protein on (silicon) chip technology for nanoscale Surface Plasmon Resonance measurements is currently ongoing.

The ESR will be trained to protein engineering and protein crystallography procedures and sample preparation for time-resolved X-ray spectroscopy. Chemical synthesis/modification of photosensitive compounds and their screening will complete the experimental training. The ESR will take part into full development of technology transfer processes. This expertise will be used to develop intellectual properties and pave the way to the commercialization of the end products of the research.

Involvement with other tasks: Protein crystallization will be carried out at UROM and preparation for Serial femtosecond crystallography experiments.

Local Training: The ESR will be trained to gene design and protein engineering including expression and purification at Molirom’s laboratory.
This ESR will be enrolled as a PhD student at the University of Rome, which offers courses in chemistry, biochemistry and physics.