Yan Huang

Yan Huang, Webster, NY US

Patent application number

Description

Published

20080299176

DRUG DELIVERY DEVICE COMPRISING CROSSLINKED POLYURETHANE-SILOXANE-CONTAINING COPOLYMERS - A drug delivery device for placement in the eye includes a drug core comprising a hydrophobic pharmaceutically active agent, and a holder that holds the drug core. The holder is made of a material impermeable to passage of the active agent and includes an opening for passage of the pharmaceutically agent therethrough to eye tissue. The device includes polyurethane-siloxane-containing copolymers crosslinked with hydrophilic monomers.

12-04-2008

20090239836

Multifunctional Ophthalmic Compositions - An multifunctional ophthalmic composition includes a nonionic oxygen-containing polymer and a surfactant. The composition can be used to treat or control ophthalmic diseases, conditions, or disorders. The composition can be a drug delivery vehicle for medicaments having low solubility in water.

09-24-2009

20100104551

METHOD FOR PROLONGING ACTIVITY OF AUTODEGRADABLE ENZYMES AND COMPOSITIONS THEREOF - A composition of a long-acting enzyme comprises the enzyme in a formulation comprising a buffer and an additive selected from the group consisting of tranexamic acid, ε-aminocaproic acid, and analogs of L-lysine other than tranexamic acid and ε-aminocaproic acid, combinations thereof, and mixtures thereof. The composition can further comprise another additive selected from the group consisting of L-lysine, L-arginine, L-ornithine (or its pharmaceutically acceptable salts; e.g., L-ornithine hydrochloride), γ-aminobutyric acid, 5-aminovaleric acid, 7-aminoheptanoic acid, glycylglycine, triglycine, N-α-acetyl-L-arginine, betaine, sarcosine, gelatin, HSA, streptokinase, tPA, uPA, non-ionic surfactants, glycerin, D-sorbitol, combinations thereof, and mixtures thereof. A method for prolonging the activity of an autodegradable enzyme comprises storing the enzyme after manufacture at a low pH, and reconstituting the acidified enzyme before use with a solution containing at least one of such additives. The method is useful to provide enzyme for wide use, which otherwise would lose activity upon long storage. In one embodiment the method is applicable to provide enzyme for inducing controlled posterior vitreous detachment.

METHOD TO IDENTIFY POLYPEPTIDE TOLL-LIKE RECEPTOR (TLR) LIGANDS - The present invention provides novel methods to identify polypeptide ligands for Toll-like Receptors (TLRs), such as TLR2, TLR4 and TLR5. The method involves the use of phage display technology in an iterative biopanning procedure. The invention also provides polypeptide TLR ligands identified by the methods of the invention. In preferred embodiments, the polypeptide TLR ligands so identified modulate TLR signaling and thereby regulate the Innate Immune Response. The invention also provides vaccines comprising a polypeptide TLR ligand identified by the methods of the invention and an antigen. The invention also provides methods of modulating TLR signaling using the polypeptide TLR ligands and vaccines of the invention.

03-12-2009

Yan Huang US

Patent application number

Description

Published

20080226673

SUBUNIT VACCINE AGAINST RESPIRATORY SYNCYTIAL VIRUS INFECTION - The present invention relates generally to methods of treating or preventing RSV infections, and more specifically, to compositions, and the use thereof, comprising one or more RSV G protein immunogen or fragment thereof capable of eliciting protective immunity without eliciting an immunopathological response or eliciting a reduced immunopathological response.

09-18-2008

Yan Huang, Jiangsu CN

Patent application number

Description

Published

20110167897

Method of Determining Surface Pore Mouth Diameter Distribution of Porous Material - A method of determining surface pore diameter distribution of a porous material is provided. A compressed gas is charged from backside of a sample of a porous body, a surface of the sample is immersed into a liquid wetting agent, and a gas pressure is regulated from high to low, such that pore mouths of the surface of the porous body are blocked by the wetting agent in an order from small to large pore sizes, and a gas flow rate is more rapidly decreased. When the pressure is decreased to a value, the gas flow rate is reduced to zero and the pressure at this time is corresponding to the largest pore mouth size of the surface of the porous body. The pore size distribution is determined by comparing the obtained gas pressure—flow rate curve (wet curve) with a gas pressure—flow rate curve (dry curve) obtained for the sample under a dry state. The pore size and the pore distribution are calculated based on the conventional bubble pressure method. The measurement of the surface pore distribution of the porous body is of great significance for investigating the support performance of the porous body.

07-14-2011

20110177232

Method for the Fabrication of Composite Palladium and Palladium-Alloy Membranes - The invention relates to a method for the fabrication of composite palladium or palladium alloy membranes. The surface of the porous ceramic substrate is modified with pencil to create a uniform and smooth layer, and the membrane is deposited via electroless plating. The advantages of the pencil modification are a reduction of the substrate surface roughness and a repair of substrate surface defects, which leads to a great improvement in the membrane uniformity and hydrogen permeation performances. This method is facile and economic, and it is especially effective on low-cost macroporous ceramic substrate materials. Furthermore, this method generates almost no pollution and therefore is environmentally benign.

07-21-2011

Yan Huang, Billerica, MA US

Patent application number

Description

Published

20110318327

TREATMENT OF SANFILIPPO SYNDROME TYPE B - Among other things, the present invention provides methods and compositions of treating Sanfilippo syndrome type B (Sanfilippo B) by, e.g., intrathecal (IT) administration of a Naglu protein. A suitable Naglu protein can be a recombinant, gene-activated or natural protein. In some embodiments, a suitable Naglu protein is a recombinant Naglu protein. In some embodiments, a recombinant Naglu protein is a fusion protein containing a Naglu domain and a lysosomal targeting moiety. In some embodiments, the lysosomal targeting domain is an IGF-II moiety.

12-29-2011

Yan Huang, Suzhou CN

Patent application number

Description

Published

20120007829

METHOD AND SYSTEM FOR TOUCH SENSOR INTERFACE FAULT DETECTION - A touch sensor interface includes one or more touch detection electrodes whose capacitance increases when touched. A processor converts the increase in capacitance into a change in a counter value. A detector compares the change in the counter value with one or more count thresholds to detect faults in the touch sensor interface.

01-12-2012

20130120053

TOUCH PAD CAPACITIVE SENSOR CIRCUIT - A touch pad capacitive sensor circuit has a signal generator that generates an oscillation signal having an oscillation frequency variable dependent on a capacitance in the sensor circuit. A switch switches a touch pad capacitive sensor of a capacitive touch pad connected to the signal generator in first and second cycles of the switch. A counter counts a first count of cycles of the oscillation signal when the sensor is connected to the signal generator in a first cycle of operation of the switch and a second count of cycles of the oscillation signal when the sensor is connected to the signal generator in a second cycle of operation. A detector detects when the first and second counts are below a low threshold number. The sensor circuit flags a valid user touch depending on an output of the detector.

Yan Huang, Shanghai CN

Patent application number

Description

Published

20120269976

MOISTURE CURABLE ANTIFOULING COATING COMPOSITIONS - A one-package moisture curable composition is provided. The composition comprises, by weight percentage based on the dry weight of the composition, from 50 to 95% at least one silane terminated polybutadiene based polymer or silane terminated polyol based polymer and from 5 to 50% at least one fluoro/fluoroalkoxy-functionalized silane; wherein the composition, after moisture cured, forms a surface whose water contact angle is larger than 101°. The composition is suitable for the applications in antifouling coatings which affords low surface energy and improved mechanical performance.

10-25-2012

20120269977

TWO-COMPONENT MOISTURE CURABLE COATING COMPOSITIONS - A two-package moisture curable composition is provided. The composition comprises a first part comprising at least one silane terminated polyurethane and a second part comprising at least one silanol terminated polysiloxane; wherein the silane terminated polyurethane based polymer has at least one end group of the general formula: -A-(CH

10-25-2012

20140088219

MOISTURE CURABLE COMPOSITIONS AND LOW SURFACE ENERGY COATING COMPOSITIONS MADE THEREFROM - A one-package moisture curable composition is provided. The composition comprises, by weight percentage based on the dry weight of the composition, from 10 to 99% at least one silane terminated polyurethane and from 1 to 90% at least one silane terminated polysiloxane; and the composition, after moisture cured, forms a surface whose water contact angle is larger than 101°. The composition is suitable for applications in coatings which afford low surface energy surface and improved mechanical performance, such as marine antifouling coating, anti-icing coating, anti-stain coating, self-cleaning coating, and non-sticky coating.

Yan Huang, San Diego, CA US

Patent application number

Description

Published

20130260444

BIOCHEMICAL PROCESS FOR SELENIUM RECOVERY FROM BIOREMEDIATION EFFLUENT OR SLUDGE - Wastewater containing selenium in a soluble form is treated in a bioreactor. Microorganisms in the reactor reduce the selenium to elemental selenium, which is insoluble. The elemental selenium is discharged from the reactor in waste sludge. The waste sludge is thickened and then treated with a cell lysis reagent to break down or dissolve micro-organism cells in the sludge. After lysis, the sludge is treated to physically separate out the remaining solids, which includes elemental selenium, for reuse.

10-03-2013

Yan Huang, Shenzhen City CN

Patent application number

Description

Published

20140115050

Method And System For Transcoding - A transcoding method, which includes a transcoding request from a client, is received by a server side. When determining that a destination file corresponding to the transcoding request exists in the server side, destination file information may be returned to the client. When determining that the destination file corresponding to the transcoding request does not exist in the server side, after executing transcoding operations by the server side, the destination file information obtained after executing the transcoding operations may be returned to the client.

04-24-2014

Yan Huang, Shenzhen CN

Patent application number

Description

Published

20140108508

Cloud subscription download method and system, and computer storage medium - A cloud subscription download method is described, which includes the following steps: a download client sends a download request to a cloud subscription server group; the cloud subscription server group queries whether a file corresponding to the download request is downloaded by the cloud subscription server group, and when the file is not downloaded, the cloud subscription server group downloads and stores the file; after the download is completed, the cloud subscription server group notifies the download client of an entry address for storing the file; and the download client downloads the file from the cloud subscription server group according to the entry address. A cloud subscription download system is further described. The method achieves high-speed download to save time, and provides stable download resources to ensure a stable download speed.

04-17-2014

20140143339

METHOD, APPARATUS, AND SYSTEM FOR RESOURCE SHARING - Various embodiments provide methods, apparatus, and systems for resource sharing. In an exemplary method, sharing metadata can be generated based on information of a resource publisher and information of at least one sharing file by a publisher client terminal. The sharing metadata can be sent to a sharing server for the sharing server to generate a sharing link. The sharing link can be published by the sharing server. The sharing metadata can be obtained from the sharing server based on the sharing link corresponding to a requested resource by a downloading client terminal. The at least one sharing file instructed by the obtained sharing metadata can be downloaded by the downloading client terminal. One or multiple files can thus be shared via a single sharing link.

05-22-2014

20140156810

METHOD AND SYSTEM FOR LOADING FILE IN WEBGAME - The present invention provides a method and a system for loading a file. The method includes: a browser sends a pre-download request to a pre-publish server beforehand, receives a download link fed back by the pre-publish server, downloads a file from a data source server through the download link, and sends a first file identifier of the pre-downloaded file and a user terminal address of a user terminal that runs the browser to a query server for storing. The browser receives a load instruction that carries a second file identifier of a file, and queries whether the file is stored locally, if the file is stored locally, reads the file locally, if the file is not stored locally, sends the load instruction to the query server, receives a user terminal address returned by the query server, sends the load instruction to a user terminal corresponding to the user terminal address according to the received user terminal address, and receives a file fed back by the user terminal.

06-05-2014

Yan Huang, Chengdu CN

Patent application number

Description

Published

20140149366

SIMILARITY ANALYSIS METHOD, APPARATUS, AND SYSTEM - Embodiments of the present invention provide a similarity analysis method, an apparatus, and a system. The method includes: acquiring file fingerprint information of a file to be analyzed; sending an analysis request that carries the file fingerprint information to at least two MDSs; selecting at least one group according to an analysis result returned by each MDS, where the analysis result includes a group number and a similarity of at least one group that has the highest similarity with the file fingerprint information and is found by the MDS; and the MDS locally queries a duplicate data block in the selected group. In this way, each MDS needs to query only a file fingerprint information set of a group that the MDS itself is responsible for, which reduces the amount of data retrieval and waiting time of reading, writing, and locking a database file.

05-29-2014

20140201169

DATA PROCESSING METHOD AND APPARATUS IN CLUSTER SYSTEM - In embodiments of the present invention, when a duplicate data query is performed on a received data stream, a first physical node which corresponds to each first sketch value and is in a cluster system is identified according to a first sketch value representing the data stream, and then the first sketch value representing the data stream is sent to the identified physical node for the duplicate data query, and a procedure of the duplicate data query does not change with an increase of the number of nodes in the cluster system; therefore, a calculation amount of each node does not increase with an increase of the number of nodes in the cluster system.

07-17-2014

Yan Huang, Shenzhen Guangdong CN

Patent application number

Description

Published

20140280859

SHARING CONTROL SYSTEM AND METHOD FOR NETWORK RESOURCES DOWNLOAD INFORMATION - A system and method to control sharing network resources download information may include a microblog sharing interface server, a sharing resources database, and a transfer server. A network resource may be received and a corresponding unique identifier may be obtained by the microblog sharing interface server. A download link entry address may be generated and posted to a microblog. The unique identifier of the network resource may be stored in the sharing resources database. The transfer server allow downloading the network resource based on corresponding download control conditions obtained from the sharing resources database using the unique identifier in the download link entry address. The source download link address of the network resource may be obtained based on the unique identifier if downloading is allowed and the source download link address sent to the client. Thus risks associated with transmission of the network resource download information may be effectively controlled.

09-18-2014

Yan Huang, Nanshan Futian CN

Patent application number

Description

Published

20140344415

MOBILE MULTIMEDIA REAL-TIME TRANSCODING SYSTEM, APPARATUS, STORAGE MEDIUM AND METHOD - An example of the present disclosure provides a mobile multimedia real-time transcoding system based of offline downloading. The system includes: a client, to submit an offline downloading and transcoding task request to the task scheduling and managing server, wherein the offline downloading and transcoding task request comprises a target mobile device type selected by a user and a target format designated by the user, and obtain a requested multimedia resource; the offline downloading and transcoding server cluster is distributed and is adapted to accept scheduling of the task scheduling and managing server, perform an offline downloading and transcoding task in a manner of performing offline downloading and transcoding in parallel.