Mary S WolffDepartment of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, New York 10029, USAPediatr Res 61:243-50. 2007

Pilot study of urinary biomarkers of phytoestrogens, phthalates, and phenols in girls

Mary S WolffMount Sinai School of Medicine, Division of Environmental Health Sciences, Department of Community and Preventive Medicine, New York, New York 10029, USAEnviron Health Perspect 115:116-21. 2007

..Self-reported acute exposure to a fogger truck, which sprayed DDT prior to 1972, was hypothesized to increase the risk of breast cancer, particularly among women exposed at a young age or diagnosed with ER+PR+ breast cancer...

Predictors of organochlorines in New York City pregnant women, 1998-2001

..In multivariate models, levels of OCs increased with age; DDE was higher in women not born in the US or Puerto Rico; PCB were higher in women who bought fresh fish and lower in those with higher body mass indices...

..This article discusses the toxicology, human exposure, and potential health effects of EDs that are likely to be important in the 21st century...

Prenatal pesticide and PCB exposures and birth outcomes

Mary S WolffDepartment of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, New York 10029, USAPediatr Res 61:243-50. 2007

..In summary, we found suggestive relationships between prenatal environmental biomarkers and birth outcomes in this population. Maternal susceptibility factors including PON1 and maternal weight contributed to the observed effects...

Pilot study of urinary biomarkers of phytoestrogens, phthalates, and phenols in girls

Mary S WolffMount Sinai School of Medicine, Division of Environmental Health Sciences, Department of Community and Preventive Medicine, New York, New York 10029, USAEnviron Health Perspect 115:116-21. 2007

..S. children using exposure biomarkers in urine. However, little is known about their variation by race, age, sex, and geography, and no data exist for newly developed biomarkers...

..The authors uncovered additional evidence that prenatal levels of organophosphate pesticide metabolites are associated with anomalies in primitive reflexes, which are a critical marker of neurologic integrity...

Characteristics of pubertal development in a multi-ethnic population of nine-year-old girls

..Early age at menarche increases future disease risk. Secular decline in age at menarche has been attributed to body size characteristics, diet, and energy expenditure. Risk factors for puberty have been less frequently explored...

Dietary flavonol intake is associated with age of puberty in a longitudinal cohort of girls

Exposure to indoor pesticides during pregnancy in a multiethnic, urban cohort

Gertrud S BerkowitzDepartment of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, New York 10029 6574, USAEnviron Health Perspect 111:79-84. 2003

..These data underscore the need to assess the potentially adverse effects of pesticide exposure on fetuses and infants and the importance of finding alternative methods for pest management to reduce pesticide exposures...

..Because small head size has been found to be predictive of subsequent cognitive ability, these data suggest that chlorpyrifos may have a detrimental effect on fetal neurodevelopment among mothers who exhibit low PON1 activity...

..Our objective was to investigate the association between asthma diagnosis and physical activity and to examine differences in these associations by race/ethnicity, weight status and caregiver education...

Associations between neighborhood resources and physical activity in inner-city minority children

..We describe how availability of physical activity resources varies by individual and block characteristics and then examine its associations with physical activity levels of Latino and black children in East Harlem, New York City...

Temporal variability in urinary concentrations of perchlorate, nitrate, thiocyanate and iodide among children

..Surrogate analysis show that single-spot urine samples reliably categorize participant's exposure providing support for the use of a single sample as an exposure measure in epidemiological studies that use relative ranking of exposure...

Luisa N BorrellDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USAArch Environ Health 59:250-5. 2004

..Neither income nor education was associated with concentrations of DDE. The authors concluded that maternal socioeconomic indicators may influence the effects of exposure to PCBs among African-American pregnant women...

Integrated pest management in an urban community: a successful partnership for prevention

..We investigated maternal functional polymorphisms of CYP17, CYP19, and CYP1B1, which control three major enzymatic steps in sex steroid biosynthesis and metabolism, in relation to childhood behaviors...

Psychological trauma associated with the World Trade Center attacks and its effect on pregnancy outcome

Matthew R LambDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USAEnviron Health Perspect 114:779-85. 2006

..Although limited by sample size, our results suggest that prenatal exposure to PCBs may affect growth, especially in girls, and that ortho-substitution is an important determinant of its effect on growth...

Prospective study of blood and tibia lead in women undergoing surgical menopause

Gertrud S BerkowitzDepartment of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, New York, USAEnviron Health Perspect 112:1673-8. 2004

..These findings do not point to substantial mobilization of lead from cortical bone during menopause...

Differential effects of the organochlorine pesticide DDT and its metabolite p,p'-DDE on p-glycoprotein activity and expression

..In summary, a minimal set of 35 AIMs is sufficient to detect population stratification and estimate the proportion of individual genetic admixture; however, the utility of these markers remains questionable...

Dietary flavonoid intake and breast cancer survival among women on Long Island

Brian N FinkDepartment of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, North Carolina, USACancer Epidemiol Biomarkers Prev 16:2285-92. 2007

..However, the effects of flavonoids on survival are not known. In a population-based cohort of breast cancer patients, we investigated whether dietary flavonoid intake before diagnosis is associated with subsequent survival...

Richard A FenskeDepartment of Environmental and Occupational Health Sciences, School of Public Health and Community Medicine, University of Washington, Seattle, Washington, USAEnviron Health Perspect 113:1455-62. 2005

..Saliva measurements of pesticides, if feasible, would overcome the limitations of urinary metabolite-based exposure analysis. Global positioning system technology appears promising in the delineation of children's time-location patterns...

Marilie D GammonDepartment of Epidemiology, University of North Carolina, School of Public Health, Chapel Hill, North Carolina 27599 7435, USACancer Epidemiol Biomarkers Prev 11:686-97. 2002

..These findings, based on the largest number of samples analyzed to date among primarily white women, do not support the hypothesis that organochlorines increase breast cancer risk among Long Island women...

..The study largely suggests no association between DDE and DDT concentrations and menstrual cycle characteristics in young Chinese women, though the weak-to-no correlation of DDE with menstrual cycle length merits further study...

..Consistent with the finding that p53(1-2-1) is a risk factor for Caucasian women was the observation of a strong interaction between race and p53 (P < 0.01)...

Dietary flavonoid intake and breast cancer risk among women on Long Island

Brian N FinkDepartment of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USAAm J Epidemiol 165:514-23. 2007

..These results suggest that US women can consume sufficient levels of flavonoids to benefit from their potential chemopreventive effects...

DDT and breast cancer in young women: new data on the significance of age at exposure

Barbara A CohnChild Health and Development Studies, Center for Research on Women s and Children s Health, Public Health Institute, Berkeley, California 94709, USAEnviron Health Perspect 115:1406-14. 2007

..Previous studies of DDT and breast cancer assessed exposure later in life when the breast may not have been vulnerable, after most DDT had been eliminated, and after DDT had been banned...

..S. studies or recent Dutch, German, and northern Québec studies. Our results will facilitate a direct comparison of the findings on PCBs and neurodevelopment when they are published for all 10 studies...

In utero p,p'-DDE exposure and infant neurodevelopment: a perinatal cohort in Mexico

..99-7.82). The majority of studies have concluded that exposure to PCBs is unlikely to be a major cause of breast cancer, but these findings indicate that further studies of genetically susceptible populations are warranted...

Construction of a flavonoid database for assessing intake in a population-based sample of women on Long Island, New York

Brian N FinkDepartment of Epidemiology, School of Public Health, University of North Carolina Chapel Hill, Chapel Hill, NC 27599, USANutr Cancer 56:57-66. 2006

..Each class of flavonoids and lignans exhibited a wide range of intake levels. This database is useful to quantify flavonoid and lignan intake for other observational studies conducted in the United States that utilize the Block FFQ...

..The decreased fecundability associated with prenatal p,p'-DDT remains unexplained. We speculate that the antiandrogenic activity of p,p'-DDE may mitigate harmful androgen effects on the ovary during gestation or early life...