CALGB-80702: Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery (H-27389)

This randomized phase III trial is studying giving oxaliplatin, leucovorin, and fluorouracil together to compare how well they work when given together with or without celecoxib in treating patients with stage III colon cancer previously treated with surgery. Patients must have stage III colon adenocarcinoma, which must be completely resected with no evidence of residual lymph node disease or metastatic disease. Patients will be randomized into one of four treatment arms.