Previous HGNC Symbols for MAGEC2 Gene

Previous GeneCards Identifiers for MAGEC2 Gene

Summaries for MAGEC2 Gene

Entrez Gene Summary for MAGEC2 Gene

This gene is a member of the MAGEC gene family. It is not expressed in normal tissues, except for testis, and is expressed in tumors of various histological types. This gene and the other MAGEC genes are clustered on chromosome Xq26-q27. [provided by RefSeq, Oct 2009]

GeneCards Summary for MAGEC2 Gene

MAGEC2 (MAGE Family Member C2) is a Protein Coding gene.
Diseases associated with MAGEC2 include Hepatocellular Carcinoma and Melanoma.
GO annotations related to this gene include ubiquitin protein ligase binding.
An important paralog of this gene is MAGEC1.

SOURCE GeneReport for Unigene cluster for MAGEC2 Gene:

mRNA Expression by UniProt/SwissProt for MAGEC2 Gene:

Tissue specificity:Not expressed in normal tissues, except in germ cells in the seminiferous tubules and in Purkinje cells of the cerebellum. Expressed in various tumors, including melanoma, lymphoma, as well as pancreatic cancer, mammary gland cancer, non-small cell lung cancer and liver cancer. In hepatocellular carcinoma, there is a inverse correlation between tumor differentiation and protein expression, i.e. the lower the differentiation, the higher percentage of expression.