Work on a syringe

A syringe is filled with water and placed in horizontal position. How much work should we do pressuring the clip with a constant force in order to remove the water from the syringe in a time t. The volume of the water in the syringe is V, the cross-sectional area of the opening is S1 and is very smaller than the area of the cross-section of the clip. Don't take into consideration the friction.

W=Fd seems a good start - what would d be then?
Pressure exerted on the plunger-end of the water would be F/S1
If the opening were the same as S1 what sort of motion would you expect from the plunger?
How does this change since the opening is "very small"?
Stuff like that? Show me.

Start the hmm problems by playing around with the concepts and something will usually strike a chord with a recent lesson or a related concept.