Lymphocytic infiltrate of Jessner is a skin condition characterized by single or multiple small, nonscaly, red, bumps on the face, neck, and upper back.[1][2] The bumps can enlarge to create a red plaque.[2] Rarely, the skin lesions cause burning or itching. The condition tends to last for several months, sometimes longer. The lesions may fluctuate between periods of worsening and periods of improvement.[1] Currently, the cause is not known.

Last updated: 7/18/2011

How might lymphocytic infiltrate of Jessner be treated?

Lymphocytic infiltrate of Jessner may require no treatment (since it can resolve spontaneously), but some patients benefit from cosmetic camouflage, photoprotection, excision of small lesions, topical steroids, intralesional steroids, oral hydroxychloroquine, systemic steroids, cryotherapy, methotrexate, thalidomide, and/or oral auranofin. There has been one case report describing treatment with a pulsed-dye laser that worked effectively in this patient after a single treatment without adverse side effects.[1]

Lymphocytic infiltrate of Jessner usually does not cause scarring. However, some cases of lymphocytic infiltrate of Jessner have been reported in association with lupus. People with lupus associated skin lesions can have more than one type of lesion, some of which may be associated with an increased risk for scarring or other adverse effects. These individuals in particular may need to be more aggressively treated.[3] If you have concerns about risks of scarring we encourage you to speak with your healthcare provider and work with him or her to develop a treatment plan.

Last updated: 7/18/2011

How can I learn about research involving lymphocytic infiltrate of Jessner?

The National Institutes of Health, through the National Library of Medicine, developed ClinicalTrials.gov to provide patients, family members, and members of the public with current information on clinical research studies. While no studies involving lymphocytic infiltrate of Jessner specifically are listed at this time, you may still be eligible for trials. We recommend calling the Patient Recruitment and Public Liaison (PRPL) Office at the National Institutes of Health (NIH) at the toll-free number listed below to speak with a specialist, who can help you determine if you are eligible for any clinical trials.

Resources on many charitable or special-fare flights to research and treatment sites and low-cost hospitality accommodations for outpatients and family members, as well as ambulance services, are listed on the Web site of the Office of Rare Diseases Research (ORDR), part of the National Institutes of Health.http://rarediseases.info.nih.gov/Resources.aspx?PageID=8

Last updated: 5/21/2009

How can I find additional information on lymphocytic infiltrate of Jessner?

Information and resources related to lymphocytic infiltrate of Jessner can be accessed by clicking here.