Current Research and Scholarly Interests
My research interests are focused on minimizing the impact of breast cancer from a diagnostic and therapuetic standpoint. Breast MRI is a powerful tool to facilitate the screening for and staging of breast cancer, and can be valuable adjunct to guide breast surgery. Oncoplastic surgical techniques optimize cosmesis after breast cancer surgery. Accelerated radiotherapy after lumpectomy decreases radiotherapy treatment times from 6 weeks to just 1 to 5 days.

Current Research and Scholarly Interests
Dr. Jeffrey led the multidisciplinary team from the Schools of Medicine, Engineering, and Genome Technology Center that invented the MagSweeper, an automated device that immunomagnetically captures live circulating tumor cells (CTCs) from cancer patient blood for single cell analysis or culture. Her lab also works on microfluidic technologies for tumor cell capture, characterization, and growth - with the goal of defining individual patient response to newer biologically-based cancer therapies.

Current Research and Scholarly Interests
My personal mission is to contribute to the overall care of the surgical patient through clinical practice, training, and education. My research interests, as they pertain to this mission, are the surgical management of reflux, minimal access surgical techniques, evidenced based surgery, surgical skills acquisition, and surgical education.

Current Research and Scholarly Interests
My main research interests include the surgical management of the morbidly obese, evidence-based surgery, and surgical education. Prior training in public health, health administration, and surgery provide a strong foundation from which to pursue these goals.The only effective and enduring treatment for morbid obesity is bariatric surgery. Like the previous public health epidemics of cancer and heart disease, surgery is the first responder to the obesity crisis.

Current Research and Scholarly Interests
Interleukin-12 is a Th1 cytokine. It is important in the cell mediated immune response. We are investigating its role as an anti-tumor cytokine to augment the immune response against cancer. We are planning a human trial.

Current Research and Scholarly Interests
Clinical trials of experimental diagnostics and therapeutics; outcomes analysis following combined modality treatment of hepatic, pancreatic, and gastrointestinal malignancies.

Current Research and Scholarly Interests
My primary research focuses on the quality of care in hospitals where minorities receive cancer treatment and the impact on cancer outcomes and disparities. As the Director of the Cancer Institute Community Partnership Program, I am moving our results into the community, training cancer advocates; building community capacity for community based participatory research in cancer and working to increase minority participation in cancer clinical trials.

Current Research and Scholarly Interests
Through a 4 pronged comprehensive program: translational and clinical research, early detection and treatment, promoting education, awareness and immunization and building partnership, we are working towards the development of new strategies that will lead to the elimination of hepatitis B worldwide and reduce the threat and incidence of liver cancer. Current research efforts focus on evaluating potential new diagnostic and treatment markers and novel targeted therapy for primary liver cancer.

Current Research and Scholarly Interests
Our main areas of interest are clinical research in shock, sepsis, multiple organ faliure and ICU pneumonia, as well as organizational characteristic of well functioning trauma centers and systems. We are also developing a program in Health Services Research focused on access to specialized, high acuity care

Current Research and Scholarly Interests
My research interests span the breath of my clinical practice. Areas of active research include the multidisciplinary treatment of hepatocellular carcinoma, technical aspects of minimally invasive pancreatic and liver surgery, and pre-operative therapy for "borderline" resectable pancreatic cancer (to bring more patients to surgery). I am also investigating trends in the management of hepatobiliary cancers in California, focusing on socioeconomic and instituional barriers to appropriate care.

Bio
I am a general and trauma surgeon, and surgical intensivist. I treat and care for injured patients and those with acute surgical emergencies, and mange critically ill surgical patients in the Intensive Care Unit.

My research is focused on evaluating the role surgical care plays in the delivery of health services in resource poor settings, in particular low and middle income countries. I am interested in barriers to access and provision of surgical care, the quality of surgical services, and outcomes research. My current projects focus on quality and cost effectiveness of care, and strategies for improving the safety and reliability of surgical delivery in resource poor settings. I have been involved in surgical program assessment projects in Cambodia, India, the UK, and the United States. From 2006-2009 I was part of the World Health Organization’s Safe Surgery Saves Lives program where we quantified the global volume of surgery and created, implemented, evaluated, and promoted the WHO Surgical Safety Checklist.

Current Research and Scholarly Interests
Clinical research focused on the diagnosis, prevention and treatment of anal cancer and its precursor lesions. Clinical trials of ablative therapy for High-grade Squamous Intraepithelial Lesions (HSIL) of the anus and perianal tissues as a means for preventing anal cancer.Basic science work in collaboration with Ronald Davis and Hanlee Ji focused on the molecular genetic and pathologic studies of anal cancers using moecular inversion probe genomic technology

Bio
Dr. Amanda J. Wheeler is a board certified surgeon who specializes in the surgical management of breast disease.

She completed her general surgical residency at Stanford University. To further her career in the treatment of breast cancer she was awarded a Surgical Society of Oncology accredited fellowship in Breast Surgical Oncology at the Harvard affiliated hospitals; Dana Farber Cancer Insitute, Brigham and Women’s Hospital and Massachusetts General Hospital. She is actively involved in clinical research and serves on the Education Committee for the American Society of Breast Surgeons. Her published research includes; the impact of screening mammography on the morbidity and mortality of breast cancer, utilization of breast MRI, the link between obesity and breast cancer and risk factors among the African American population for breast cancer. She has also written multiple chapters in leading textbooks and collaborated with other nationally recognized experts at MD Anderson, Memorial Sloan Kettering, Stanford University and Harvard University.

Dr. Wheeler previously was the Medical Director of the Meridian Park Legacy Breast Cancer Program and was in private practice in Portland, Oregon for five years before returning to Stanford. She enjoys playing golf, painting and yoga.