I am running Windows 7 and use Adobe Reder frequently. Never had a problem. Last week, whenver I try to open a PDF file, I get a warning box "Windows cannot access the specified device, path, or file. You may not have the appropriate permissions to access the item."

The only thng that changed recently was a couple large Windows updates... I am always suspect when a large update occurs. I uninstalled the Reader and Download Manager and ree-installed themm. No change in performance.