Leiomyomas are rare,
benign, smooth muscle neoplasms. Piloleiomyomas are the most common type
of Leiomyomas in the skin and usually present as multiple lesions in
early adolescence as firm papules or nodules.

They are
characteristically painful in response to pressure or low temperature.

Facial piloleiomyomas
are infrequent.

Patients with
multiple Leiomyomas should be screened for renal cancer, and women
should be referred for regular gynecological evaluations to rule out
uterine Leiomyomas.