Increase genome editing efficiency with optimized CRISPR-Cas enzymes

CRISPR genome editing is a powerful tool with significant promise for molecular medicine. However, CRISPR systems have inherent challenges, including off-target editing and on-target efficiency. For successful editing experiments, investigators must therefore use and understand experimental best practices and optimized tools. In this webinar, learn about the innovative solutions IDT scientists and collaborators have developed for better CRISPR genome editing, including optimal delivery strategies and the new Alt-R HiFi S.p. Cas9 Nuclease V3, specifically designed to produce dramatically reduced off-target editing while maintaining strong on-target performance in living cells.

Genome editing with the CRISPR-Cas9 and CRISPR-Cas12a (Cpf1) systems has been a groundbreaking development in basic biomedical research, with significant implications for personalized medicine and the treatment of human diseases.