If cast, Winfrey will portray a desperate mom trying to talk her daughter out of committing suicide.

The show's lead producer, Scott Sanders, who is also working with Winfrey on a Broadway revival of the musical The Color Purple, has hinted that his friend would be more than ready to take on the role.

He tells the New York Times, "Oprah has had a longstanding desire to act on Broadway. She understands how unique and challenging performing live on stage will be as an actress."

'Night, Mother first opened on Broadway in 1983 with Anne Pitoniak and Kathy Bates, spawned a film version in 1986 with Sissy Spacek and Anne Bancroft, and most recently had a short-lived Broadway revival in 2004, starring Brenda Blethyn and Edie Falco.