Notes:

Products protected by valid patents are not offered for commercial supply in countries where the sale of such products constitutes a patent infringement. Any reference to patents also includes supplementary protection certificates (SPCs) and / or patent term extension for products protected by those patents.

Hikal has the expertise and instrumentation to determine and confirm the structure of developmental compounds. Our reaction capabilities include:

Ammoxidation

Schiemann reaction

Nitration

Friedel-Crafts reaction

Liquid phase Oppenauer oxidation

Amino acid transformation

Swern oxidation

Ortho metalation process

High temperature / high pressure oxidation

Aldol condensation

Suzuki reaction

Hazardous materials handling:

Birch reduction

- Chlorine

Catalytic hydrogenation

- Bromine

Darzens glycidic ester condensation

- Chlorosulfonic acid

Sandmeyer reaction

- Cyanogen chloride

Chiral synthesis

- Carbon disulfide

Hetero Diels-Alder reaction

Low temperature reaction; - 100°C

1,3 polar addition

High temperature reaction; + 280°C

Mannich reaction

High pressure reaction; 30kg/cm2(g)

Hikal has delivered projects involving:

Single-step / multi-step synthesis

Hazardous chemicals

Challenging unit operations such as:

Oxidation

Bromination

Azidation

Chlorination

Ammoxidation (gas phase)

THF recoveries

Project Management

Hikal has a project management system that adheres to project delivery within the scope, duration, budget, and quality parameters of clients. Our project / product managers are trained in the PRINCE2 ® project management method.

Taloja

The Taloja plant was commissioned in 1997 in technical collaboration with Merck & Co. Inc, USA. The 60,000 square meter site facilitates manufacturing of fungicides, insecticides and intermediates. The site manufactures on - patent active ingredients for innovator companies.

Panoli

The Panoli plant is spread over 126,000 square meters. Hikal acquired
this manufacturing site from Novartis in 2000. The plant was formerly
a Sandoz plant that was commissioned in 1987.
It is audited frequently by US and European innovator companies. It is
involved in manufacturing of specialty chemicals, insecticides and
intermediates.

Key features:

Accredited with OHSAS 18001, ISO 14001 and ISO 9001
certification

High capacity bromination facility

High temperature reaction facility (+240°C)

Process development lab

Chemical plant – manufacturing specialty chemicals

Expanded capacity for key starting raw materials

Continuous extraction systems

Established in 1988, Hikal is a company built on enduring relationships