A senior Pakistani government official says the death toll from a massive Islamic State suicide bombing at a Sufi shrine in the country's south the previous day has risen to 80.

The police commissioner in Hyderabad, the largest city closest to the town of Sehwan where the shrine was attacked, says a total of 250 people were wounded in the explosion.

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Qazi Shahid Pervez said on Friday that local hospitals were overwhelmed and that several of the critically wounded were taken to Karachi, Pakistan's largest city on the Arabian Sea coast. He says military aircraft assisted in the evacuation of the wounded.

The Sehwan shrine, which reveres Muslim Sufi mystic, is frequented by the faithful of many sects of Islam but the majority of the worshippers are usually Shiite Muslims. The Islamic State group reviles Shiites as heretics.

Afghanistan's President Ashraf Ghani has condemned the horrific attack. Ghani says his security forces are battling all terrorist groups, including the Islamic State.

Ghani's statement on Friday says that militant groups always seek to "target civilians in Afghanistan and other parts of the world."

Ghani says that "Sufis always preach peace and brotherhood among people." But, he added, "terrorists once again proved that they have no respect for Islamic values."