4SICKLE CELL DISEASETotal hip replacement in such patients who are less than forty years old has been associated with high rates of complications and revisions. Also, the majority of such patients with sickle cell disease have been reported to have a high prevalence of failure of components fixationThe purpose of the present study was to analyze the results after primary total hip arthroplasty with cement in a group of patients who had sickle cell disease

5Problems anatomic abnormalities infection of the hip during childhoodTransfusions and anemiaAllo immunisationPulmonary InfarctusRevisions

6The anatomic abnormalitiesThe anatomic abnormalities may includeabnormal location of neurovascular structures secondary to soft-tissue contractures,an abnormal location of the hip center,a limb-length discrepancy,a small acetabulum and femoral canalincreased anteversion of the proximal part of the femur.

19Problems anatomic abnormalities infection of the hip during childhoodTransfusions and anemiaAllo immunisationPulmonary InfarctusRevisions

2010 hips in patients who had had infection of the hip during childhoodAll the hips had cemented total hip replacements. The age of the patients at the time that the infection was contracted was an average of 12 years).The average age of the patients at the time of the total hip arthroplasty was 32.4 years. The interval between active infection and arthroplasty was 24 years. All the hips had a quiescent period of infection of more than ten years. The average duration of follow-up was 8 years (range, five to fifteen years).Two hips had recurrence of infection.

35ConclusionThe management of hip arthroplasty with sickle cell disease requires recognition of anatomical deformitiesAssessment begins in the preoperative period with recognition of significant risk factors, including previous surgery systemic medical conditions, as well as selection of suitable components.