Previous studies have shown that histamine is not only involved in allergic disease, it also may have a potential antitumor effect. At Baylor College of Medicine, the lab of Dr. James Versalovic, Milton J. Finegold Professor of pathology and immunology and pathologist-in-chief at Texas Children’s Hospital investigated whether the probiotic Lactobacillus reuteri 6475, which is … Continue reading →

“If you asked a group of scientists which is more important for a cell, maintaining the integrity of its DNA containing all of the organism’s genetic information, or the fidelity of transcription – the process that transcribes DNA into RNA, which leads to protein synthesis – the vast majority would agree that repairing DNA is … Continue reading →

Medulloblastoma is the most common type of solid brain tumor in children. Current treatments offer limited success and may leave patients with severe neurological side effects, including psychiatric disorders, growth retardation and cognitive impairment. Sonic Hedgehog, one of the four biologically distinct subtypes of medulloblastoma, is named after the cellular pathway that is impaired in … Continue reading →

The nuclear factor I-A (NFIA) gene is important for both normal brain development and brain tumor growth. One way to discover paths that can lead to brain malignancy is to first better understand the process of normal brain development. The Deneen lab has followed this strategy. They have studied the mechanisms by which normal brain … Continue reading →

Each month, From the Labs posts an image representative of research conducted at Baylor College of Medicine. These three are the most viewed images of 2017. Read the article corresponding to each image: Lighting up tumor blood vessels Mouse brain with Batten disease Lipid droplet dynamics in C. elegans From the Labs wishes all its … Continue reading →

In 2015, Dr. Lucy Liu, now a Ph.D. graduate in neuroscience from the Bellen lab, discovered that a number of genes involved in neurodegeneration promote damage to neurons and glia by inducing high levels of free radicals (oxidative stress) and accumulation of lipid droplets in glia. Liu continued this line of research and in 2017 … Continue reading →