Effects of Magnesium on Spermiogenesis

Abstract

Years ago the women had to face society’s blame due to their childless marriages. The problem of infertility has increasingly been extended to anomalies in the male partner. Male fertility may also have various causes: reduced volume of ejaculate, decreases number and motility of sperms and increased proportion of abnormal (injured) sperms. It was found that as a result of ATP and cAMP supply in vitro in demembranated models the length of time of the sperms’ motility grew thirtyfold (122.0 min) compared to the control (4.2 min) [1,2]. This is made possible by the fact that the energy required for the motion of sperms is released from the ATP by the ATPase [3]. According to Morisava [4] the motility of sperms needs the joint presence of cAMP and Mg ATP. It was found that the formation of ATP, as well as, cAMP is a magnesium intensive process [5,6]. It was also found in vivo that magnesium increases the sperm motility, while the sperm production inreases up to 80% [7].