According to Variety, "The Blind Side" is the first movie ever "driven solely by a top female star" to break $200 million. Over the weekend, the drama box office receipts totaled $208.5 million.

In comparison, Sandra's A-list counterparts have come close, but never pulled in moviegoers in such big numbers. Julia Roberts' "Erin Brockovich" – which is often compared to "The Blind Side" — made $125.6 million domestically, while Meryl Streep's "The Devil Wears Prada," earned $124.7 million.

The only other female-centric film to ever crack the $200 million club was 2002's "My Big Fat Greek Wedding," which starred the then unknown Nia Vardalos.

And "The Blind Side's" box office bounty could continue to grow, according to Warner Bros. President of Domestic Distribution Dan Fellman.

"And we're not even done. I think 'Blind Side' has another $30 million left," Fellman told the entertainment trade mag.

With the exception of the disappointing "All About Steve," Sandra has had a stellar year with "The Proposal," which pulled in an impressive $164 million domestically. The actress' films have grossed a whooping $1.72 billion domestically over her career.