MendelianRandomization

Mendelian Randomization Package

Encodes several methods for performing Mendelian randomization
analyses with summarized data. Summarized data on genetic associations with the
exposure and with the outcome can be obtained from large consortia. These data
can be used for obtaining causal estimates using instrumental variable methods.

News

MendelianRandomization v0.2.2

Penalization of weights altered to correspond to Rees et al 2017 (submitted): penalization is now about the median estimate, only variants with heterogeneity p-value less than 0.01 are penalized.

MendelianRandomization v0.2.1

Minor fix on extract.pheno.csv function that was making SNPs out of order.
Minor fix on p-values from mr_ivw and mr_egger functions.