I have for 2 days had severe right neck and knee pain accompanied by both joints on thumbs, have been taking Ibuprofen but with out much relief. Sleep has been distrupted for 2 nights with the addition of severe itching all over particualrily the feet. The pain is now in most major joints of my body.

The first thing that comes to mind with this set of symptoms is possible rheumatic fever. It is only a guess, and you should see a doctor as soon as possible to find out what's really going on, but there is that one possibility, unless, of course, you already have a history of some sort of rheumatic disease.