The DynaPro Plate Reader III performs high-throughput screening of excipients and buffers for optimal formulation in situ in standard microwell plates, detecting aggregation as well as conformational and colloidal stability indicators.

CG-MALS combines a Calypso II and DAWN or miniDAWN to characterize the affinity and absolute molecular stoichiometry of drug-target binding, without labeling or immobilization. It also analyzes self-association at low, moderate and high concentrations.

A DAWN or miniDAWN MALS detector, combined with a Wyatt SEC column and the Optilab T-rEX dRI detector, determine absolute molar masses and sizes of peptides, proteins and other biomacromolecules independently of column calibration.

CG-MALS combines a Calypso and DAWN or miniDAWN to characterize the affinity and absolute molecular stoichiometry of simple or complex biomolecular interactions. CG-MALS requires no labeling or immobilization, addressing self-association as well as hetero-association.

Key ingredients in cosmetics, the paper industry and food products, polysaccharides are also critical materials in biomedical applications such as vaccines and blood coagulants. Characterize all types of polysaccharides by SEC combined with Wyatt's on-line light scattering, dRI and viscosity detectors.

Need to characterize your nanoparticles under hundreds of solvent conditions in the space of a few hours? The DynaPro Plate Reader III measures size distributions by DLS, in situ in standard 96-, 384- or 1536-well microtiter plates. A camera conveniently photographs each well to identify precipitates.

The Möbiuζ is the only zeta potential detector capable of hands-free, high-throughput measurements by coupling to an autosampler. It measures charge and size simultaneously to monitor aggregation or degradation caused by the applied electric field.

Resources

Wyatt Technology is the recognized leader in light scattering instrumentation and software for determining the absolute molar mass, size, charge and interactions of macromolecules and nanoparticles in solution.