(Cat? OR feline) AND NOT dog?
Cat? W/5 behavior
(Cat? OR feline) AND traits
Cat AND charact*

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i. protecting the hydroxyl group of compound of formula (VI) or its salts (for example, protecting with benzyl chloride),

ii. oxidizing the methyl group of compound of formula (V) to aldehyde of compound (IV) iii. reducing the aldehyde group of compound (IV) to alcohol of compound (III), and iv. deprotecting or debenzylating compound (III) to (II).

The compound of formula (VI) can be prepared for example according to the procedure describe in Example 12 and Example 22 of US5382600.

The protecting of the compound of formula VI of Step (i) can be done for example by benzylating the compound of formula (VI) or its pharmaceutically acceptable salt thereof with a benzylating reagent in the presence of a base to obtain the compound of formula (V).