Johns Hopkins Outpatient Center
Appointment Phone: 443-997-0270

Background

Dr. Nazarian is a graduate of Stanford University School of Medicine, the Peter Bent Brigham Internal Medicine, and the Johns Hopkins University Cardiovascular Medicine and Clinical Cardiac Electrophysiology programs. For two years in a row he received the Richard S. Ross Clinician Scientist and the Johns Hopkins Clinical Research Scholars Awards. His clinical interests include the care of patients with atrial and ventricular arrhythmia, cardiomyopathy, and implantable cardiac devices. Dr. Nazarian performs procedures including implantation of permanent pacemakers and implantable cardioverter defibrillators, and catheter ablation for atrial and ventricular arrhythmias. He recently patented a noninvasive method for detecting the source of errant electrical signals that cause ventricular tachycardia. Dr. Nazarian is an Associate Professor of Epidemiology, Bloomberg School of Public Health.

Patents

An embodiment in accordance with the present invention provides a magnetic assist device to treat congestive heart failure. The device includes at least two magnets disposed on the heart and synchronized to the QRS wave, as sensed by an electrode disposed within the heart. In an embodiment to provide left ventricle assistance, one of the magnets is disposed on the endocardium of the right ventricle and the other magnet is positioned in a lateral branch of the coronary sinus. During systole, the two magnets are attracted to one another to aid in contraction of the heart muscle. During diastole, the two magnets repel one another to aid in relaxation of the heart muscle. A generator disposed transdermally is conductively connected to the two magnets and the electrode, such that the generator powers the two magnets and the electrode. The generator can be powered by an internal battery and/or external drive.

A non-invasive method of producing a three-dimensional cardiac electrogram characteristic map for use in catheter ablation of ventricular tachycardia includes receiving left ventricle three-dimensional image data of a patient's heart; segmenting a left ventricle image of the patient's heart based on the left ventricle three-dimensional image data into scar tissue, normal myocardium tissue and left ventricle cavity regions; determining scar tissue thickness and normal myocardium tissue thickness for a plurality of portions of the left ventricle image of the patient's heart; receiving predetermined data that associate a value of at least one electrogram characteristic to each scar tissue thickness and each normal myocardium tissue thickness for the plurality of portions of said left ventricle image of said patient's heart; and generating the three-dimensional cardiac electrogram characteristic map of the at least one electrogram characteristic corresponding to the left ventricle image of the patient's heart based on the predetermined data.

A non-invasive method of producing a three-dimensional cardiac electrogram characteristic map for use in catheter ablation of ventricular tachycardia includes receiving left ventricle three-dimensional image data of a patient's heart; segmenting a left ventricle image of the patient's heart based on the left ventricle three-dimensional image data into scar tissue, normal myocardium tissue and left ventricle cavity regions; determining scar tissue thickness and normal myocardium tissue thickness for a plurality of portions of the left ventricle image of the patient's heart; receiving predetermined data that associate a value of at least one electrogram characteristic to each scar tissue thickness and each normal myocardium tissue thickness for the plurality of portions of said left ventricle image of said patient's heart; and generating the three-dimensional cardiac electrogram characteristic map of the at least one electrogram characteristic corresponding to the left ventricle image of the patient's heart based on the predetermined data.

Activities & Honors

Honors

Medical Scholars Research Fellowship, Stanford University, 1996

Ruth L. Kirschstein National Research Service Award, National Institutes of Health, 2003