QTDT

Linkage Disequilibrium Analyses for Quantitative
and Discrete Traits

QTDT provides a convenient one-stop interface for family based
tests of linkage disequilibrium. The general models described
by Abecasis et al. (2000a,
b) are supported,
and can be used to analyse quantitative or discrete traits in
nuclear families, with or without parental genotypes, or extended
pedigrees. In addition, QTDT can calculate exact p-values by permutation
even when multiple linked polymorphisms are tested. The tests
described by Allison (TDTQ5, 1997), Rabinowitz (1997), Monks et al.
(1998) and Fulker et al. (1999) are also supported.