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Glutamine plays key roles in protein metabolism, cell volumizing, and anti-catabolism. Glutamine also increases your ability to secrete Human Growth Hormone, which helps metabolize body fat and support new muscle growth. Glutamine's anti-catabolism ability prevents the breakdown of your muscles. Some people use glutamine for digestive system conditions such as stomach ulcers, ulcerative colitis, and Crohn's disease. It is also used for depression, moodiness, irritability, anxiety, insomnia, and enhancing exercise performance.