The article argues that Philip Roth’s Kepesh saga — The Breast (1972), The Professor of Desire (1997), and The Dying Animal (2001) — dramatically morphs, with regard to sexuality and imaginative flight, Sartre’s account, in Being and Nothingness (L’être et le néant, 1943), of the origins and possibilities of consciousness and their relation to desire. Indeed, desire, the dominant theme of Roth’s trilogy, corresponds to Sartrian outlooks on transcendent possibility or existential freedom. In Being and Nothingness, moreover, Roth appears to have located, identified with, and artistically transformed outlooks on consciousness and artistic creativity. Roth’s inspiration for imagining a character who exists as a breast, sans body, may also have emerged from Sartre’s treatise, the outlooks of which allow for better appreciation of the concerns and fictive possibilities suggested by TheProfessor of Desire and The Dying Animal.