Aberrant Crypts

Does anyone have any evidence of aberrant crypts (AC) being able to
regress? Numerous ACs are formed while only a few neoplasms may
developed. Do ACs actually regress or do most remain ACs while a few
progress to neoplasms? When studying ACs from the same colon it is very
apparent that they are in different stages of development. Although, it
is not clear which direction they are developing. Are they on their way
to becoming ACs or are they regressing back to a normal cell? E-mail
messages would be helpful. Thank you for your help and interest.
(ziphelms at aol.com)