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Several incarnations of political groups promoting lesbian issues have evolved; 13 lesbian organizations were active in Mexico City in OR Login with Redtube Premium. Discussion from historians caused further questioning of what qualifies as a lesbian relationship. The most extensive early study of female homosexuality was provided by the Institute for Sex Research , who published an in-depth report of the sexual experiences of American women in Ideas about women's sexuality were linked to contemporary understanding of female physiology. Factors that add to risk of heart disease include obesity and smoking , both of which are more prevalent in lesbians. Queen Anne was rumored to have a passionate relationship with Sarah Churchill , Duchess of Marlborough, her closest adviser and confidante.