In 2000, Time magazine included him in the top 100 innovators of XXI Century. This year created the Mono project, a .Net Framework for Unix like systems.

In 2003, Ximian was acquired by Novell for 30M$. In 2011Miguel founded Xamarin company to continue with the Mono development.

Miguel is a FLOSS leader that contributed very actively to the development of free software with Mono and Midnight Commander, but also in other projects like Gnumeric, Bonobo, Evolution or Red Carpet, and trying to provide free tools as an alternative to proprietary products. It also has a great entrepreneurial spirit, as has been seen.