Trend over time

Chronic myeloid leukaemia is not among the 20 most common causes of cancer death in the UK, accounting for less than 1% of all cancer deaths (2016).[1-3]

In males in the UK, chronic myeloid leukaemia is not among the 20 most common causes of cancer death (less than 1% of all male cancer deaths). In females in the UK it is not among the 20 most common causes of cancer death (less than 1% of all female cancer deaths).

54% of chronic myeloid leukaemia deaths in the UK are in males, and 46% are in females.

Chronic myeloid leukaemia mortality rates (European age-standardised (AS) rates) are similar to the UK average in all the UK constituent countries.

About this data

Chronic myeloid leukaemia mortality is strongly related to age, with the highest mortality rates being in older people. In the UK in 2014-2016, on average each year two-thirds (66%) of deaths were in people aged 75 and over.[1-3] This largely reflects higher incidence and lower survival for chronic myeloid leukaemia in older people.

Age-specific mortality rates rise steeply from around age 60-64. The highest rates are in the 90+ age group for males and females.

Mortality rates are similar between males and females in most age groups.

Chronic Myeloid Leukaemia (C92.1), Average Number of Deaths per Year and Age-Specific Mortality Rates per 100,000 Population, UK, 2014-2016

About this data

Chronic myeloid leukaemia European age-standardised (AS) mortality rates for males and females combined decreased by 73% in the UK between 1971-1973 and 2014-2016.[1-3] The decrease was larger in females than in males.

For males, chronic myeloid leukaemia AS mortality rates in the UK decreased by 72% between 1971-1973 and 2014-2016. For females, chronic myeloid leukaemia AS mortality rates in the UK decreased by 75% between 1971-1973 and 2014-2016.

Over the last decade in the UK (between 2004-2006 and 2014-2016), chronic myeloid leukaemia AS mortality rates for males and females combined decreased by 29%. In males AS mortality rates decreased by 29%, and in females rates decreased by 31%.

Chronic myeloid leukaemia mortality rates have decreased overall in all broad age groups in males and females combined in the UK since the early 1970s.[1-3] Rates in 0-24s have decreased by 88%, in 25-49s have decreased by 91%, in 50-59s have decreased by 91%, in 60-69s have decreased by 85%, in 70-79s have decreased by 73%, and in 80+s have decreased by 37%.

About this data

There is evidence for an association between chronic myeloid leukaemia (CML) mortality and deprivation for males in England, but there is no evidence for an association for females.[1] England-wide data for 2007-2011 show European age-standardised mortality rates are 33% higher for males living in the most deprived areas compared with the least deprived, but for females the rates are similar for those living in the least and most deprived areas.[1]

The estimated deprivation gradient in CML mortality for males and females living in the most and least deprived areas in England has not changed in the period 2002-2011.[1] It has been estimated that there would have been around 15 fewer cancer deaths each year in England during 2007-2011 if all people experienced the same mortality rates as the least deprived.[1]

References

About this data

Data is for: England, 2007-2011, ICD-10 C92.1

Deprivation gradient statistics were calculated using mortality data for 2007-2011. The deprivation quintiles were calculated using the Income domain scores from the Index of Multiple Deprivation (IMD) from the following years: 2004, 2007 and 2010. Full details on the data and methodology can be found in the Cancer by Deprivation in England NCIN report.

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