Nearly half of all patients with obstructive sleep apnea have insomnia symptoms, and in some, but not all cases, these insomnia symptoms are caused by the obstructive sleep apnea. The purpose of this study is to find out what type of insomnia symptoms are caused by obstructive sleep apnea and therefore most likely to respond to obstructive sleep apnea treatment with continuous positive airway pressure (also known as CPAP) and if additional treatment with cognitive-behavioral therapy for insomnia is beneficial.

CPAP therapy for sleep apnea and contact control (placebo/sham for cognitive-behavioral therapy for insomnia)

Device: CPAP

Treatment for sleep apnea

Other Name: Continuous positive airway pressure therapy

Behavioral: CC

Placebo (sham) for insomnia

Other Name: Contact control

Sham Comparator: sham CPAP+CC

sham CPAP (ineffective CPAP--placebo/sham for sleep apnea) and contact control (placebo/sham for cognitive-behavioral therapy for insomnia)

Device: sham CPAP

Placebo for sleep apnea

Other Name: Sham (placebo) continuous positive airway pressure

Behavioral: CC

Placebo (sham) for insomnia

Other Name: Contact control

Active Comparator: CPAP+CBT

CPAP therapy for sleep apnea and cognitive-behavioral therapy for insomnia

Device: CPAP

Treatment for sleep apnea

Other Name: Continuous positive airway pressure therapy

Behavioral: CBT

Treatment for insomnia

Other Name: Cognitive-Behavioral Therapy for Insomnia

Eligibility

Ages Eligible for Study:

18 Years and older

Genders Eligible for Study:

Both

Accepts Healthy Volunteers:

No

Criteria

Inclusion Criteria:

Sleep Apnea

Insomnia

Age >18

Exclusion Criteria:

Sedative/psychoactive drug use recently

Other clinically significant sleep disorders

Previous treatment for OSA

Requires oxygen or bilevel PAP therapy

Clinically unstable medical condition

Recent shift work

Significant alcohol use

Other clinically significant causes of insomnia

Illicit drug use

Prescription stimulants

Safety restrictions

Unable to treat sleep apnea with positive airway pressure therapy

Communication barriers

Cognitive impairment

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01824472