For a jacketed bullet,I've had very good luck with Remington's good old 240 gr. Semi-Jacketed HP whether in a factory load or over a stiff charge of H110 in a handload. Last deer I used it on it went through a big doe's boiler room wiping out the top of the lungs and clipping the heart off at the main plumbing connection then out the other side. At about 25-30 yards when hit, she just fell over. Very impressive bullet I'd say.