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Identity by Descent in Island-Mainland Populations

J. A. Hartigan and B. Rannala
A new measure of the extent of population subdivision asinferred from allele frequencies at microsatellite loci is proposed and tested with computer simulations. This measure, called R S T , is analogous to WRIGHTâS T FS in representing the proportion of variation between populations. It differs in taking explicit account of the mutation process at microsatellite loci, for which a generalized stepwise mutation model appears appropriate. Simulations of subdivided populations were carried out to test the performance of R S T and F S T . It was found that, under the generalized stepwise mutation model, R S T provides relatively unbiased estimates of migration rates and times of population divergence while F S T tends to show too much population similarity, particularly when migration rates are low or divergence times are long. In the paper byTHOMAS NAGYLAKI (GENETICS 139: 473-485; January, 1995) entitled âThe inbreeding effective population numberin dioecious populations,â a computer errorafter final proofreading replaced some, but not all, of the symbols C and Pwith E and P,respectively. Thus, both I>âand denote expectation, and both E P and P denote probability. P[N] = (f ,â- â)[ ;]+âA[;]N. On page 432, column two should begin, âover, the entire collection of populations. For the BDI demographic model, j,is given by (h+ A) / ( + A) as shown above (equation 21 ) .â
http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.pngGeneticsGenetics Society of Americahttp://www.deepdyve.com/lp/genetics-society-of-america/identity-by-descent-in-island-mainland-populations-HkFVDg2jUD