腸内環境で変わるストレス反応性 : 腸内フローラとストレス(日本心身医学会・東北大学脳科学GCOE合同シンポジウム:医学・生物学これからの50年の大問題:心脳問題をいかに解明してゆくか,2010年,第51回日本心身医学会総会ならびに学術講演会(仙台))Gut Microbiota and Stress(Symposium/A Vital Problems of Medical and Biological Sciences in Comimg 50 years: How to Elucidate the Problem of the Mind-brain Interaction)

抄録

Gut microbes live in a state of harmonious symbiosis with each other and their host, however, a disordered balance amongst gut microbes is now thought to be an associated or even causal factor for chronic medical conditions as varied as obesity and inflammatory bowel diseases. While evidence is still limited, there are rapidly coalescing clusters of evidence which point to the possibility that variations in the composition of gut microbes may be associated with changes in the normal functioning of the nervous system. This review focuses on these data and suggests that the concept should be explored further to uncover possible links to mental health and psychiatric disorders.