Easily administered as a top dressing or in your horse's regular grain portion

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Is primarily used to treat lameness in horses

Phenylbute is a nonsteroidal anti-inflammatory drug (NSAID). Formulated to administer as a top dressing or mixed in with your horse's regular grain portion. Includes dispensing scoop.

Phenylbute is for the relief of inflammation associated with the muscles, joint and bones in horses. If used to treat inflammation associated with infections, specific drugs to kill the infection should be used at the same time.

How does Phenylbute work?
Phenylbute blocks the body's production of substances that trigger inflammation.

How is it given?
Phenylbute is given with food. Always follow the dosage instructions provided by your veterinarian. If you have difficulty giving the medication, contact your veterinarian.

What results can I expect?
Phenylbute does not cure a disease but can effectively reduce symptoms of pain and inflammation. The response varies from horse to horse but can be dramatic. Pain relieving effects can generally be seen within hours of giving Phenylbute. Improvement of inflammation can generally be seen after several days. Phenylbute is not a cure for arthritis, and the signs may come back if Phenylbute is discontinued.

What form(s) does it come in?
This medication comes in powder form. Phenylbutazone also comes in a tablet form.

More Information

Brand Name
Phenylbute

Pronunciation
FEN-ill-byute

Common Drug Name
Phenylbutazone

What should I discuss with my veterinarian while considering Phenylbute?
Talk to your veterinarian about what tests and exams may be necessary while your horse is taking Phenylbute. Also discuss how long the treatment period will be and what type of outcome is expected. You and your veterinarian should talk about any other treatment options that are recommended for your horse. For arthritic horses, weight loss programs, exercise programs, supplements, and other aids may be helpful.

Tell your veterinarian if your horse has liver or kidney disease, stomach ulcers, has a bleeding disorder, may be pregnant or is nursing, or if you intend to breed your horse.

Discuss withdrawal times if your horse is a performance horse.

Notify your veterinarian of any other medications or supplements your horse is taking, and also if your horse has had any reactions to previous medications.

What should I do if I miss a dose?
If you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give two doses at once.

What is the most important information I should know?
At the first sign of side effects (listed below), contact your veterinarian.

Who should not take it?
Not for use in horses hypersensitive (allergic) to Phenylbute. Do not use in horses with stomach ulcers or a history of stomach ulcers, horses that are anemic, or have diseases of the bone marrow, kidney, liver, or heart. Do not use in pregnant or lactating horses unless benefits outweigh the risks.
Avoid use in debilitated horses, foals, and ponies unless benefits outweigh the risks, since the possibility of toxic side effects is increased in these animals.

Since Phenylbute can mask lameness, it is unethical to use it prior to a soundness exam.

Do not use in horses intended for food.

This medication should only be given to the horse for which it was prescribed.

What side effects may be seen when taking Phenylbute?[Back]
You may see signs of oral or gastric ulcers. In adult horses, these signs may include decreased appetite, weight loss, mild colic, poor performance, depression, lying down more than normal, diarrhea, accumulation of fluid under the belly, and anemia with signs of pale gums and weakness. In foals, you may also see teeth grinding, drooling, weakness, and nursing for only short periods of time. Effects related to the kidney may result in changes in drinking or urination habits. Stop using Phenylbute and consult your veterinarian if you notice any of the above side effects.

If your horse experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.

How is it stored?
Store this powdered medication at room temperature in a tight, light-resistant, childproof container. Keep out of the reach of children and pets.

What should I do if I know of or suspect there has been an overdose?
If an overdose should occur, you may see changes in drinking and urinating including blood in the urine; increased breathing rate, weakness, or seizures; liver injury, with yellowing of the gums and
whites of the eyes; anemia, with pale gums; or ulcers in the mouth or stomach, with signs of pain, loss of appetite and weight loss. If you know or suspect your horse has had an overdose, or if you
observe any of these signs in your horse, contact your veterinarian immediately.

What should I avoid when giving my pet Phenylbute?
Notify your veterinarian of any other medications, including vitamins and supplements, your horse is taking while receiving Phenylbute. Consult your veterinarian before using this medication with phenytoin, valproic acid, oral anticoagulants such as warfarin, corticosteroids, chlorpheniramine,
diphenhydramine, penicillin G, furosemide (Salix), and other NSAIDS such as aspirin and flunixin (Banamine), since interactions may occur.

Where is more information available?
Ask your veterinarian, consult with one of our pharmacists at 1-800-447-3021, or see the Patient Information Sheet on this medication.

If you are calling us during regular pharmacy hours and have left a message: please allow our pharmacy professionals two hours to respond; messages left after hours will be answered on the next business day within 2-4 hours.

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