Overview

Replacement Information

Key Spec Table

Empirical Formula

CAS #

C₁₄₆H₂₁₃N₄₃O₄₀

88813-36-9

Description

Overview

A biologically active neuropeptide that has been shown to inhibit secretion of somatostatin, insulin, and pancreatic polypeptide. Also induces repolarization and reduces free Ca2+ due to interference with voltage-activated Ca2+ channels. Inhibits ω-conotoxin GVIA-sensitive Ca2+ channels in parasympathetic neurons. Reported to have an inhibitory role in transmission of nociceptive information.

Brochure

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision

17-October-2007 JSW

Synonyms

GWTLNSAGYLLGPHAIDNHRSFHDKYGLA-NH₂

Description

A biologically active neuropeptide consisting of 29 amino acids. Shown to inhibit secretion of somatostatin, insulin and pancreatic polypeptide. Also induces repolarization and reduces free Ca2+ due to interference with voltage-activated Ca2+ channels. Inhibits ω-conotoxin GVIA-sensitive Ca2+ channels in parasympathetic neurons. Reported to have an inhibitory role in transmission of nociceptive information.