Science of Skin Aging – Antioxidants vs. Free Radicals

posted Oct 4, 2013, 11:18 AM by rbayani@crowdfundingplanning.com

The Arthricept product is formulated with a healthy dose of turmeric and curcumin which contain the antioxidant rich curcuminoids. Turmeric is an effective source of the antioxidant, glutathione that stops the “free radical cascade”. In combination with piperine, from black pepper, antioxidants are delivered at the cellular level to help prevent oxidative damage from free radicals. In recent years antioxidant research has increased in intensity from varied areas and disciplines within the medical community. Overwhelming evidence has accumulated showing that antioxidants may prevent oxidative damage and thus protect against the adverse effects of oxidants.

The process of oxidation in the human body damages cell membranes and other structures. When oxygen is metabolized, it creates "free Radicals" which steal electrons from other molecules causing damage to cell membranes. As a whole our bodies are constantly producing these free radicals as a normal process of metabolism and our bodies need free radicals in limited quantities to function properly. However when we experience stressful situations, smoke, drink alcohol, play in the sun, live in polluted areas and many other factors - we accelerate the oxidation process which increases the amount of free radicals in our bodies.

Without antioxidants free radicals can cause extensive cell damage and contribute to a whole list of chronic diseases including but not limited to chronic degenerative diseases, ranging from stroke and fibromyalgia, to sinusitis, arthritis, vision problems, Parkinson's, Alzheimer's and cancer. In a normal healthy, younger, well-nourished and non-stressed person, antioxidants are naturally and normally in abundance through out the body. But as a person grows older, or when people on high fat, high carbohydrate diets or are ill, our body’s ability to manufacture antioxidants diminishes predisposing our bodies to different chronic health conditions and premature aging.

As we age, our skin becomes dry due to the loss of the ability to retain moisture, collagen breakdown, and loss of elasticity due to cross-linking of collagen fibers. All these are a result of free radical production. As a result, wrinkles start forming and there is a loss of elasticity.

Age-related skin changes, including loss of elasticity, age spots and wrinkles, are the result of genetically programmed changes (internal factors) and environmental wear-and-tear on the skin (external factors) caused by free radical production or oxidative stress. It is true that extrinsic factors (like photo aging) do cause more pronounced damage but the resulting changes actually occur deep within the skin at the cellular or sub nuclear level affecting our DNA strands and telomere length. Therefore to reverse the damage, key antioxidants must penetrate the layers of skin and reach the cellular level or be taken internally in a formulation that provides higher bioavailability through the bloodstream.

The science and of skin aging is evolving. It is not as simple as we once thought. Old theory would suggest that free radicals play a role in skin aging and antioxidants counter free radicals thus increasing antioxidants should result in younger healthier skin but this has not necessarily been the case.

Free radicals are molecules with an unpaired electron causing instability and making them highly reactive; they are formed during normal metabolism from interactions with our toxic environment. Antioxidants and antioxidant enzymes work to neutralize the free radicals that would otherwise damage our DNA.

The free radicals attack lipids, cell membranes and our essential DNA code deep within the nucleus of the cell. When this happens, they form new free radicals from other stable molecules in what is known as the ROS cascade or free radical cascade. The resultant free radical cascade is deleterious to our cells causing inflammation, cross-linking of collagen fibers and disease.

Thus, antioxidants have the ability to stabilize free radicals but in doing so create other free radicals, thereby creating the need for a master antioxidant that can terminate the free radical cascade. Terminal “Electron Rich” Antioxidant molecules like Glutathione can "donate" an electron to a free radical, but will remain stable and NOT turn into one! This ends the electron-stealing chain reaction responsible for collagen mutation and loss of skin elasticity.

Comments

Disclaimer

Health Naturally Terms, Legal Conditions and Herbal Safety Guidelines
This Agreement is between Company and you ("you" or "Customer") This Section sets forth the terms and conditions which apply to the use by you of the Company Sites (as defined below) and any other subscription, product or service offered for sale by Company and/or its affiliates (collectively, "Company "). The right to use any product or service offered by Company is personal to you and is not transferable to any other person or entity. Company reserves the right to make changes to the Company sites, policies, and these Terms at any time without notice.

1.Use of the Company Sites.

The Company Sites contain links to other Web sites, resources and advertisers. Company is not responsible for the availability of these external sites nor does it endorse or is it responsible for the contents, advertising, products or other materials made available on or through such external sites. Under no circumstances shall Company be held responsible or liable, directly or indirectly, for any loss or damage caused or alleged to have been caused to a user in connection with the use of or reliance on any content, goods or services available on such external site. You should direct any concerns to such external sites to the administrator or webmaster.

2. Disclaimer of Warranty; Limitation of Liability

Company neither endorses nor is responsible for the accuracy or reliability of any opinion, advice or statement on the Company sites, nor for any offensive, defamatory or obscene posting made by another person. Under no circumstances will the Company be liable for any loss or damage caused by your reliance on information obtained through the content on the Company sites. It is your responsibility to evaluate the accuracy, completeness or usefulness of any information, opinion, advice or other content available through the Company sites. Please seek the advice of professionals, as appropriate, regarding the evaluation of any specific information, opinion, advice or other content, including but not limited to financial, health, or lifestyle information, opinion, advice or other content.

3. Indemnification

You agree to defend, indemnify and hold harmless Company, its affiliates and their respective directors, officers, employees and agents from and against all claims and expenses, including attorneys' fees, arising out of the use by you of the Company Sites, including claims by other users of your equipment, access, products or membership.

4. Legal Disclaimer

Statements made by Company have not been evaluated by the US Food and Drug Administration. The FDA Dose not evaluate or test herbs. These products are not intended to diagnose, treat, cure or prevent any illness or disease. Consult with your physician for diagnosis or treatment. Use herbs as per instructions and always watch for any allergic reactions.

The information presented on this site is not presented with the intention of diagnosing any disease or condition or prescribing any treatment. It is offered as information only, for use in the maintenance and promotion of good health in cooperation with a licensed medical practitioner.

In the event that any individual should use the information presented on this website without a licensed medical practitioner's approval, that individual will be diagnosing for him or herself.
No responsibility is assumed by the author, publisher or distributors of this information should the information be used in place of a licensed medical practitioner's services. No guarantees of any kind are made for the performance or effectiveness of the preparations mentioned on this website. Furthermore, this information is based solely on the traditional and historic use of a given herb, or on clinical trials that are generally not recognized by any US government agency or medical organization.
This information has not been evaluated by the US Food and Drug Administration, nor has it gone through the rigorous double-blind studies required before a particular product can be deemed truly beneficial or potentially dangerous and prescribed in the treatment of any condition or disease.

5.Herbal Safety Guidelines

Before using an herb you are unfamiliar with, find out its medicinal properties. Research it thoroughly and/or consult with an appropriately qualified practitioner or expert. If you are taking prescription drugs, or have a medical condition check with an appropriately qualified practitioner before using herbs medicinally. Herbs have shown overwhelming evidence that they work. Just because a small amount works well does NOT mean that more is better. As individuals we all have different constitutions, sensitivities, allergic reactions and possible health conditions. The following are merely guidelines. They include herbs offered on our websites. This list does not help with administering information on possible interactions and contraindications with prescription medicine. This needs to be discussed with your physician.

Should I check with my doctor or healthcare provider before using a supplement?

This is a good idea, especially for certain population groups. Dietary supplements may not be risk-free under certain circumstances. If you are pregnant, nursing a baby, or have a chronic medical condition, such as, diabetes, hypertension or heart disease, be sure to consult your doctor or pharmacist before purchasing or taking a supplement. While vitamin and mineral supplements are widely used and generally considered safe, you may wish to check with your doctor or pharmacist before taking these or any other dietary supplements. If you plan to use a dietary supplement in place of drugs or in combination with any drug, tell your health care provider first. Many supplements contain active ingredients that have strong biological effects and their safety is not always assured in all users. If you have certain health conditions and take these products, you may be placing yourself at risk.
Some supplements may interact with prescription and over-the-counter medicines.

Taking a combination of supplements or using these products together with medications (whether prescription or OTC drugs) could under certain circumstances produce adverse effects. Be alert to advisories about these products, whether taken alone or in combination. For example: Coumadin (a prescription medicine), ginkgo biloba (an herbal supplement), aspirin (an OTC drug) and vitamin E (a vitamin supplement) can each thin the blood, and taking any of these products together can increase the potential for internal bleeding.

Some supplements can have unwanted effects during surgery.

It is important to fully inform your doctor about the vitamins, minerals, herbals or any other supplements you are taking, especially before elective surgery. You may be asked to stop taking these products at least 2-3 weeks ahead of the procedure to avoid potentially dangerous supplement/drug interactions -- such as changes in heart rate, blood pressure and increased bleeding - that could adversely affect the outcome of your surgery.
Statements made by Company have not been evaluated by the US Food and Drug Administration. The FDA Does not evaluate or test herbs. These products are not intended to diagnose, treat, cure or prevent any illness or disease. Consult with your physician for diagnosis or treatment. Use herbs as per instructions and always watch for any allergic reactions.

Privacy Policy

EFFECTIVE DATE: Oct 30, 2013

This Privacy Policy (Policy) discloses the practices of Company concerning personal information we obtain about you. By using Company, in any way accessing Company, or using other services of Company (collectively the Services), you are accepting the practices described in this Policy.

Security

Company takes every precaution to protect our users and members Sensitive Information, both online and offline. Your Sensitive Information is password-protected for your privacy and security. Sensitive Information is encrypted and is protected online with the best encryption software in the industry - SSL.

Sensitive Information is also protected offline in our offices. Only employees who need the information to perform a specific job (for example, a billing clerk or member services representative) are granted access to Sensitive Information. Furthermore, all employees are kept up-to-date on our security practices and changes in those practices. Finally, the servers that we store Sensitive Information on are kept in a secure environment. If you have any questions about the security at our website, you can send an email to us using Company online contact form.

Information collection use and sharing policy

This Policy notifies you of: (a) what personal information of yours is collected when you access Company and/or use the Services or purchase any product; (b) how the information is collected; (c) how the information is used and shared; (d) our efforts to maintain the security of Sensitive Information; and (e) other details concerning your personal information and our policies.

This Policy does not apply to the practices of companies that Company does not own or control, or to people that we do not employ or manage.

Information Collection and Use

Information collected by Company is stored in a single, secure database, accessible only by Company. Company collects information from our paying customers or other persons who use, attempt to use, or purchase Company products or the services at several different points and from different sources, all or some of which may apply to you.

* Registration

When you sign up as a customer or potential customer, we ask for, and you are required to give, your name, address, zip code, telephone number, email address, credit card or checking account number, and credit card expiration date. Once you register as a customer with us, you are not anonymous to us.

* Cookies

Cookies are alphanumeric identifiers that we transfer to your computers hard drive through your Web browser.

* Log Files

Company automatically receives and records information on its server logs from your Web browser, including your IP address, cookie information, and the page you requested. We use IP addresses and cookies to analyze trends, administer the site, track members and users movements, and gather broad demographic information for aggregate use. IP addresses are not linked to your personal information.

* Information from Other Sources

For reasons such as improving personalization of our Service (for example, providing better product recommendations or special offers that we think will interest you), we might receive information about you from other sources and add it to our account information. We also sometimes receive updated delivery and address information from our shippers or other sources so that we can correct our records and deliver your next purchase or communication more easily.

Use of Information

Information we collect is generally used for the following purposes:

To build features that will make the services available on our site easier to use. This includes faster search requests, better member support and timely notice of new services and special offers.

To resolve disputes, troubleshoot problems and enforce our Terms and Conditions of Use. At times, we may look across multiple members or users to identify problems or resolve disputes, and in particular we may examine your information to identify members using multiple Member Ids or aliases.

Sharing of Information. We may use the personal information that you supply to us and we will bring selected retail opportunities to you via direct mail, email, online and telemarketing. Company may sell or rent aggregated statistical information and user, member or former member specific information, including name, address, telephone number and payment information, to our marketing partners or other third-parties. If you want Company to stop sharing information it has about you in the future, you may notify us of this fact by contacting Company's Member Services department.

We reserve the right to disclose personal information, including Sensitive Information, when we believe that such disclosure is appropriate to comply with the law or a request by a government official, to protect the rights or property of Company, or to enforce our Terms and Conditions of Use. In the event that Company or substantially all of its assets are acquired by a third party, member information and Sensitive Information may be some of the transferred assets.

Use of Data Collected

We use your personal, demographic and profile data to enhance your experience at our site and to enable us to present content we think you might be interested in. We use your contact information to send you information about our company and promotional material from our partners. We may also use your personal, demographic and profile data to improve our site, for statistical analysis, for marketing and promotional purposes, send SMS alerts or notification, and for editorial or feedback purposes for our advertisers. Information collected by us may be added to our databases and used for future telemarketing, SMS text-messaging, e-mails or postal mailings regarding site updates, new products and services, upcoming events, and/or status of orders placed online. By using this site, you agree that you may be contacted in any manner contemplated in this section even if your number is found on a do not call registry, in-house list or similar registry.

Agents

We employ other companies and individuals to perform functions on our behalf. Examples include fulfilling orders, delivering packages, sending postal mail and e-mail, removing repetitive information from member lists, analyzing data, providing marketing assistance, processing credit card payments, and providing member services. They have access to personal and Sensitive Information needed to perform their functions, but may not use it for other purposes.

Special Offers and Announcements

Active customers and former customers will occasionally receive information on products, services, special deals, and a newsletter.

Other Sites

Company forwards users and members to other sites. Please be aware that Company is not responsible for the business and privacy practices of these other sites. We encourage you to be aware of this when you leave our site and to read the legal notices and privacy policies of each and every website you visit.

Correction/Updating Personal Information

If a members personal information changes we will endeavor to provide a way to correct or update that members personal data provided to us.

Notification of Changes

If we decide to change our Policy, we will post these changes on our Homepage or provide other notification of our revised Policy so our users and members are always aware of what information we collect, how we use it, and when we disclose it.

Children’s Online Privacy Protection

Company serves general users of the World Wide Web. We support and comply with the Children’s Online Protection Act (COPPA) and we do not knowingly collect information from children under the age of 13, nor do we share such information with third parties. Children under the age of 18 may use Company only with the involvement of a parent or guardian.

Individual customers who reside in California and have provided their personal information to Company may request information about our disclosures of certain categories of personal information to third parties for their direct marketing purposes. Such requests must be submitted to us using Company online contact form. Within thirty days of receiving such a request, we will provide a list of the categories of personal information disclosed to third parties for third-party direct marketing purposes during the immediately preceding calendar year, along with the names and addresses of these third parties. This request may be made no more than once per calendar year. We reserve our right not to respond to requests submitted other than to the address specified in this paragraph.