Preparation and Storage

ReconstitutionAdd deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

General Info

Alternative names

OTTHUMP00000020114

OTTHUMP00000020115

OTTHUMP00000020116

Plasma retinol binding protein 4

Plasma retinol-binding protein

Plasma retinol-binding protein(1-176)

PRBP

PRO2222

RBP

RBP4

RDCCAS

RET4_HUMAN

Retinol binding protein 4

Retinol binding protein 4 interstitial

Retinol binding protein 4 plasma

see all

FunctionDelivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.

Involvement in diseaseDefects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.