Haigh Group - Mammalian Functional Genetics

Research Overview

The laboratory of Associate Professor Jody J. Haigh uses/develops cutting edge transgenic mouse models and ES/iPS cell-based technologies to better understand cellular fate, memory and transformation. The group is presently interested in understanding the role of Zeb and Snai family of transcriptional modulators in normal haematopoietic cell differentiation and lineage commitment/function, as well as their roles in the leukaemia development. Using induced pluripotent stem (iPS) cell based technologies we are also developing iPS cell lines derived from primary leukaemia samples to better understand the molecular basis of leukaemia and to develop novel drug screening platforms.