Killer Snails: Assassins of the Sea is a deck-building game in which the players are scientists collecting predatory cone snails that prey on fish, worms and other mollusks. The type of snail determines its strength and the type of prey eaten, and the snails produce different peptides. To win the game, the player must build a venom arsenal of the correct peptide toxin combinations. The winning combination of peptides always changes as it is drawn at the beginning of each game. Cards with scientific events ranging from "research", which provides a peek at part of the solution, to "tsunami", which shifts all the prey cards on the table, offer strategic opportunities for victory. The game offers a dynamic play experience in which players have to react and adjust their strategy accordingly. Created in collaboration with the American Museum of Natural History.

Warnings: The event was originally listed with rules of "Killer Snails (1st)." It has been changed to "Killer Snails (1st Edition)."