IRANDERMA

A 3-year-old boy presented with a few weeks history
for a pruritic vesiculobullous eruptions on his face, lower trunk and
extremities....

What's your diagnosis?

Dx: Chronic Bullous Disorder of
Childhood (CBDC)

CBDC is a blistering disease
characterized by large, tense, and clustered subepidermal bullae. The
lesions are distributed mainly on the lower part of the trunk, pelvic
region, groins, and lower extremities. Presence of annular and serpiginous
erythematous patches with bullae arranged at the periphery of the patches
is a typical feature in CBDC.

The immunologic hallmark of the
disease is linear IgA deposits at the basement membrane zone.

Dapsone or sulphapyridine usually
control the eruption rapidly and spontaneous remission seems to occur in
the majority of the cases after an average of 3-4 years.