When you first enter the Poke Transfer Lab, a scientist will ask you if you want to experiment with the system. He will give you a quick rundown on how everything works. Transferring Pokemon is fairly simple.

Transferring Pokemon

In order to transfer Pokemon, you need two Nintendo DS Systems. The Nintendo 3DS also work for this process. Start wireless communications on the system that is running Pokemon Black or White. The other system with the Gen four Pokemon game will bring up a DS Download Play button at the main menu. Click the button and select six Pokemon from your PC to transfer over to Pokemon Black and White. Remember, once the Pokemon are transferred over, you cannot transfer them back! Not all Pokemon can be transferred:

After sending Pokemon to the Poke Transfer Lab, you will play a short mini-game. Launch Poke Balls at the Pokemon as they dodge from bush to bush. After all Pokemon are caught, the game will end, and the Pokemon will be transferred to your PC.