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Citation and License

Genome Biology 2006, 7:212
doi:10.1186/gb-2006-7-4-212

Published: 26 April 2006

Abstract

The majority of disease resistance genes in plants encode nucleotide-binding site
leucine-rich repeat (NBS-LRR) proteins. This large family is encoded by hundreds of
diverse genes per genome and can be subdivided into the functionally distinct TIR-domain-containing
(TNL) and CC-domain-containing (CNL) subfamilies. Their precise role in recognition
is unknown; however, they are thought to monitor the status of plant proteins that
are targeted by pathogen effectors.