Legalon Evidence Review

At www.natrx.com.au we aim to offer natural therapies with the best available research. We intend that these products and the information about their evidence will assist the safe and effective prescribing of natural therapies.

An injectable form of Legalon is manufactured for emergency treatment of hepatotoxicity from mushroom poisoning.
The exact mechanisms of action are yet to be completely understood, but appear to be multitarget.(12,13)

Product Specific Evidencemeans that the exact herb or supplement is the same as the one used in the clinical trial/s.General Evidence refers to research about the all the different preparations of the herb or supplement.

Levels of EvidenceTherapies are ranked according their strength of evidence.

Strongest Evidence is a systematic review of all the research on a subject. A meta-analysis is one technique for combining the results of many clinical trials.Strong Evidence consists of at least one well conducted double-blind, randomised, controlled clinical trial.Medium Evidenceis a well designed controlled trial that is not randomised, or blinded. Weak Evidence includes the opinions of respected experts that are based on clinical experience, descriptive studies, or reports from other expert committees. The traditional use of natural therapies where collective expert knowledge is passed down for many generations is another example.Weakest Evidenceis patient testimonials, case reports, animal and cell experiments and expert opinions that are based on little proof of evidence.