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Comfortis is the first FDA-approved, chewable, beef-flavored tablet that kills fleas and prevents flea infestations.

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8928a

6 Dose

$97.99$94.99

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**Note: This product requires a veterinarian's prescription to purchase.At checkout you will need to provide your
veterinarian's FAX or email address. We will then send him or her a prescription verification that he or she
will need to sign and return before we can ship you this product.

Dogs over 120 Ibs and Cats over 24 lbs should be administered the appropriate combination of tablets.
Administer COMFORTIS chewable tablets with food for maximum effectiveness.
COMFORTIS is a chewable tablet and is readily consumed by dogs when offered by the owner just prior to feeding. Alternatively, COMFORTIS chewable tablets may be offered in food or administered like other tablet medications. COMFORTIS chewable tablets should be administered at monthly intervals.
If vomiting occurs within an hour of administration, redose with another full dose. If a dose is missed, administer COMFORTIS chewable tablets with food and resume a monthly dosing schedule.
Treatment with COMFORTIS chewable tablets may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with COMFORTIS chewable tablets should continue the entire year without interruption.
To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product.

Contraindications:

There are no known contraindications for the use of COMFORTIS chewable tablets.
Federal USA law restricts this drug to use by or on the order of a licensed veterinarian
Warnings:
Not for human use. Keep this and all drugs out of the reach of children.

Precautions:

COMFORTIS chewable tablets are for use in cats, dogs, kittens and puppies 14 weeks of age and older

The primary target of action of COMFORTIS chewable tablets in insects is an activation of nicotinic acetylcholine receptors nAChRs. Spinosad does not interact with known insecticidal binding sites of other nicotinic or GABAergic insecticides such as neonicotinoids, fiproles, milbemycins, avermectins, and cyclodienes. Insects treated with spinosad show involuntary muscle contractions and tremors resulting from activation of motor neurons. Prolonged spinosad-induced hyperexcitation results in prostration, paralysis, and flea death. The selective toxicity of spinosad between insects and vertebrates may be conferred by the differential sensitivity of the insect versus vertebrate nAChRs.