Abstract

During the course of a study of sprue and allied deficiency states,1 low or "flat" oral glucose tolerance curves were observed very frequently in the affected individuals. This was not a novel observation, for other observers had had the same experience, and furthermore, had suggested that this finding serve as a diagnostic aid in the recognition of sprue.2, 3

A review of the pertinent literature revealed considerable difference of opinion on the interpretation of the low oral glucose tolerance curve.2, 4, 5, 6 It was felt that before relying too greatly upon the contour of the curve as a diagnostic