The Seahawks have not been underdogs of more than a touchdown since 2012, when they fell 13–6 to the 49ers. Seattle has actually beaten the number three consecutive times when it has closed as an underdog of 7.5 points or more, according to the OddsShark NFL Database—in the franchise’s previous 10 games in that scenario, it had gone 1–9 against the spread.

On the flip side, New England is 7–3 against the spread the last 10 games in which it’s been favored by more than seven points, including a 2–0 start this year. The Patriots have won three of the past four meetings with the Seahawks, capped off by a 28–24 victory in Super Bowl XLIX two seasons ago.

The other one-loss team in the NFL will be away from home in Week 10, as the Cowboys (7–1) visit the Steelers (4–4) as 2.5-point road underdogs in the late afternoon window.

The Cowboys are expected to have quarterback Tony Romo back on the sidelines for the first time this season, presumably as a backup to rookie Dak Prescott. They have won five of the past seven versus the Steelers, who are coming off a road loss to the Ravens but are 7–2 straight up in their last nine games as favorites.

Earlier in the day, two AFC West teams will be tested in tough road games as well. The Chiefs (6–2) sit just a half-game behind the idle Raiders for the lead in the AFC West, and they visit the defending NFC champion Panthers (3–5) as three-point underdogs.

The Chiefs are riding a four-game winning streak and have gone 7–3 straight up and against the spread in their last 10 road games. But they are also just 1–5 against the spread in their previous six games following a win, and they beat the Jaguars 19–14 last week.

Coming off a 30–20 loss to the Raiders on Sunday night, the Broncos are listed as 2.5-point underdogs on the road against the Saints (4–4). Denver is 4–0 straight up and 3–1 against the spread in the past four meetings with the Saints. New Orleans is eyeing a rare three-game winning streak—the Saints have lost six of their last seven games following back-to-back wins.