Whilst I can see where you are coming from in this question, I do have to point out that I feel this is a very misguided approach you are taking. We need to remember that Shakespeare wrote plays for a specific audience, and therefore did not write to please himself or to express his own life experience. For example, Macbeth was written specifically for James I, the new King of England, and was performed in 1606. Shakespeare's survival as a playwright depended on his ability to write plays that would please his aristocratic audience and flatter them sufficiently. In this case, James I was also the sixth king of Scotland, and his descendants can be linnked back to the character of Banquo. This is why Banquo is depicted as such an honest, honourable man in the play and is compared to Macbeth to reinforce this. Also, in Act IV scene 1, the final apparition that Macbeth sees is of eight kings, the last one with a glass or mirror in his hand and Banquo following behind. This was clearly meant to reflect the fact of King James to indicate the way that he is the descendant of Banquo and to point out how he fulfills the prophecy of the witches.

Thus, whilst I salute your attempt to identify biographical details from Shakespeare's life that led him to focus on a particular theme, you need to be aware of the political realities and responsibilities that he faced as a playwright who had to write plays that would please the aristocracy of his day. He was not free to write as he wished. Although of course his plays do contain timeless and eternal themes, we need to remember that they also are a reflection on Elizabethan court life.