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Sertoli Cell Biology, Second Editionsummarizes the progress since the last edition and emphasizes the new information available on Sertoli/germ cell interactions. This information is especially timely since the progress in the past few years has been exceptional and it relates to control of sperm production in vivo and in vitro.

Fully revised

Written by experts in the field

Summarizes 10 years of research

Contains clear explanations and summaries

Provides a summary of references over the last 10 years

About The Author

Excerpt from Hartman Award from Society for the Study of Reproduction Carl G. Hartman Award(Supported by a grant from Cook Medical)This award is the most prestigious award conferred by the Society for the Study of Reproduction. Each year, this award recognizes an exemplary research career in reproductive biology. The 2013 recipient of ...

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Table of Contents

PrefaceSertoli cell anatomy and cytoskeletonFetal Sertoli cellsEarly postnatal interactions between Sertoli and germ cellsStem cell NicheRole of DMRT1Hormonal regulation of spermatogenesis through Sertoli cells- TestosteroneActivins and inhibinsInitiation of spermatogenesis and the cycle of the seminiferous epitheliumRetinoic acid metabolism and the cycle of the seminiferous epitheliumSertoli cell specific transcription and the Sertoli cell cycleMicro-RNA and spermatogenesisLarge noncoding RNAs (lncRNAs) and lncRNA-mediated epigenetic regulationBiochemistry of Sertoli-Germ cell junctions, spermiation and movement of germ cells across the barrierImmunology of the TestisDiversity and similarities in Sertoli cells from different speciesHuman Sertoli cells and the SCO syndromeGene Knockouts that affect Sertoli cell function