Clear insulin does not need to be mixed; however, cloudy insulin should be mixed by gently rolling the bottle between your hands. Do not shake. Then, check that there are no particles at the bottom of the bottle.

Remove needle cap and pull the plunger to draw in an amount of air equal to the amount of prescribed insulin. Wipe the top of the insulin bottle with alcohol, then insert the needle through the rubber stopper of the insulin bottle and inject air into the bottle.

Turn the bottle upside down with the needle in it. Pull the plunger on the syringe and withdraw insulin, not air, past the number of units needed.

If there are air bubbles, they must be removed. Without taking the needle out of the insulin bottle, push the insulin back into the bottle and draw again. Or snap the syringe sharply with a finger, then push the plunger to expel air into the bottle.

You may inject through one layer of clothing, although it's best to inject directly through your skin. Inject the insulin by holding the syringe like a pencil with one hand, and inserting the needle into the fold of your skin. Then release the pinch. Push in the plunger and inject the insulin. Pause for five seconds and then withdraw the needle. Do not re-cap the needle. Discard it into the puncture-resistant container.

Insulin is best injected into the abdomen because of quick and consistent absorption; but it can also be injected into fatty tissue between skin and muscle anywhere that large blood vessels, nerves and bones are not close to the surface.

The upper arm

The abdomen

The thighs

The buttocks

Once you become comfortable with injecting yourself, it takes very little time.