The Manitowoc Company, Inc. (NYSE: MTW) shares climbed 8.91% to $22.79 on report of Icahn stake. Carl Icahn reported a 7.77% stake in Manitowoc, according to a 13D filing. Based on the 13D filing, Icahn intends to hold discussions with the company's management and Board of Directors relating to the separating of the company's Crane and Food service segments into two separate companies.

Ignyta, Inc. (NASDAQ: RXDX) shares rose 7.03% to $7.00 following the report of the FDA orphan drug and rare pediatric disease designations for entrectinib for neuroblastoma.

Revolution Lighting Technologies, Inc. (NASDAQ: RVLT) gained 5.46% to $1.35 after the company announced a strategic distribution partnership with Fastenal.

Juno Therapeutics Inc. (NASDAQ: JUNO) shares surged 4.24% to $50.79 following the release of 8-K indicating payment of $20 million cash and $1.6 million shares to Opus Bio as conditions to satisfy license agreement.