WEDDING and meeting planners take note: Harlem may soon get its first, full-service hotel.

The land, a vacant parcel at the southwest corner of Park Avenue and East 125th Street opposite the Metro North station, is currently owned by the abutting New York College of Podiatric Medicine.

The school is negotiating a 48-year lease with a renewal option with developer Michael Caridi, chairman of the Brooklyn-based construction company, SRC Industries.

At this point, the Marriott and Westin hotel chains have expressed interested in the site.

“We’re proposing 183 to 204 rooms in a full-service hotel,” said Caridi, who hopes to break ground on the 26-to-30-story project in September. “It’s a godsend for Harlem. Politically, everyone seems to be on board with it.”

Indeed, Kenneth J. Knuckles, the former Dinkins administration Commissioner of General Services now leading the Harlem Empowerment Zone, is eager to facilitate its construction.

“It’s something we would like to see happen,” Knuckles said.

The land, however, must be rezoned to allow the project to move forward and the developer is discussing that aspect with City Planning. If it comes to a vote before the City Planning Commission, Knuckles, who also sits on that board, said he might have to recuse himself.

While Caridi’s company generally provides construction and construction management services, others believe he is equipped to carry out the project.

He is a partner in the Holiday Inn on West 57th Street and says he is “talking to a few different people” about coming in on the Harlem deal.

“He has the equity and wherewithal to carry this out himself,” said a source who is familiar with Caridi.

Caridi started pursuing the Harlem Hotel after learning of a favorable feasibility study by Marriott.

A Marriott spokesperson for its New York City properties confirmed it is in conversations with Caridi’s firm to develop a 180-room Courtyard by Marriott.

Caridi is negotiating with the major operators now to see which one gets to carry its flag north of Central Park. The eventual winner will also drive the devilish details of the $100 million-plus hotel now being designed by SCR Design.

As currently planned, the mixed-use project would also have 200,000 square feet of commercial office space, 60,000 square feet of retail shopping, 30,000 square feet of catering for banquets and meetings, a small pool and underground parking.

Additionally, the architects are toying with creating an evening dinner and jazz club on the transitional 13th or 14th floors between the lower commercial offices and upper hotel rooms.

“The area with the rich history of 125th Street could be a nice draw,” said Michael Cuddy, director of architecture for SCR. “There would be a view out over the lower buildings and you could see the river and Central Park and the surrounding areas.”

According to Caridi, the hotel and attendant offices and retail shopping will create somewhere between 1,800 and 2,000 permanent jobs. A spokesperson for the Podiatric College said the negotiations are ongoing.

Joseph A. Del Vecchio of Murray Hill Properties/TCN, who is representing a retail project at 71 East 125th St. across the street, said, “It’s about time. That portion of 125th Street is so desolate and it would be great to see development there.”