Linking Sequence and Structure
with Function

A little about our research:

Our laboratory uses both computational and experimental methods to improve our understanding of how protein structures mediate protein function. Here, we develop and use the tools of bioinformatics and computational structural biology to integrate the information coming out of the genome projects with available tertiary structural information. One primary goal of our computational work is to develop a methodology for "rational protein design" that can be used in our laboratory to engineer new functionalities into proteins.