Muscarinic antagonists

(Asthma Tx)

Ipratropium- competitive block of muscarinic receptors, preventing bronchoconstriction. Also used for COPD, as is tiotropium, a long-acting muscarinic antagonist.

4

Corticosteroids

(Asthma Tx)

Beclomethasone, fluticasone- inhibit the synthesis of virtually all cytokines. Inactivate NF- kappa B, the transcription factor that induces the production of TNF- alpha, among other inflamm agents. 1st-line therapy for chronic asthma.