Happy Trails is based in Sac-Town, north of Shady Sands, and does most of its business with New Reno and on the road to Salt Lake City. They are competitors with the Crimson Caravan for trade. After several seasons of bad trading, and since the loss of contact with New Canaan in 2281, the company is in dire financial straits and is preparing to launch an expedition to New Canaan via Zion Canyon in order to reconnect with the Mormons there.

None of the members can be pickpocketed when the player meets them at the Northern Passage.

Happy Trails can have 1 of 2 fates: they return to power because the White Legs were driven out, or the Sorrows'sevacuation allows the White Legs to keep Happy Trails out. The latter causes the company to go bankrupt.

They are affiliated with the courier during the Honest Hearts DLC in Fallout New Vegas