Fantasy Football Week 6: Kevin Kolb Is a Must-Start This Week

Fantasy football is all about matchups. A weak defense can make a mediocre quarterback look like a stud. That's the situation that Arizona Cardinals quarterback Kevin Kolb finds himself in for Week 6.

With starting quarterbacks Cam Newton, Drew Brees and Jay Cutler all on byes, owners will have to look elsewhere for production from the important quarterback position.

Kolb is a sneaky play at quarterback in Week 6 and could finish as one of the top performers at his position.

The Arizona Cardinals, who have been pathetic on offense in 2012, match up with the Buffalo Bills, who have been just as pathetic on defense. This matchup could set Kolb up for a big fantasy day.

The Bills defense is coming off of a game in which they made 49ers quarterback Alex Smith look like a fantasy beast. Smith torched the Bills for 303 yards and three touchdowns, good enough for 28 fantasy points, according to ESPN standard scoring rules.

Through five games, the Bills have given up big fantasy numbers three times to Smith, Tom Brady and Mark Sanchez.

Brady scored 31 fantasy points against the Bills in Week 4, throwing for 340 yards and three touchdowns. Jets quarterback Mark Sanchez started the season with a solid game against Buffalo, tossing three touchdowns and earning his owners 20 points.

Of course, Brady is an elite quarterback, but nobody would argue that title for Smith or Sanchez.

Kolb could join the ranks of those quarterbacks who have starred against the Buffalo defense.

Before the Week 5 debacle at St. Louis, in which Kolb was sacked nine times, he had strung together two straight decent fantasy starts.

The Arizona signal-caller threw for 222 yards and two touchdowns against his former team in Week 3 and 324 yards and three touchdowns against Miami in Week 4.

Helping Kolb's case for a fantasy start is the fact that Arizona will rely heavily on the pass with running backs Beanie Wells and Ryan Williams both out with injuries.

Plus, don't forget that Kolb gets to throw to Larry Fitzgerald, one of the best receivers in the game. Kolb has also formed a relationship with receiver Andre Roberts, tossing two touchdowns to him in Week 4.

Look for Kolb to throw early and often against the Bills and finish with a solid fantasy output. Owners who have a hole to fill at quarterback should not shy away from him.

With quarterbacks like Brady, Tony Romo, Eli Manning and Matthew Stafford having tough defensive matchups this week, it's not improbable to think that Kolb could finish inside of the top 10 for Week 6.