Volume 7.12 | Apr 10

How Immune Cells Facilitate the Spread of Breast Cancer
Researchers discovered that certain immune cells are persuaded by breast tumors to facilitate the spread of cancer cells. The tumor sends out signaling molecules that through a number of steps cause the immune system to produce lots of neutrophils. These neutrophils are able to block the actions of T cells. [Press release from the Netherlands Cancer Institute discussing online publication in Nature] Press Release|Abstract

The Development and In Vivo Function of T Helper 9 Cells
The authors summarize the current understanding of the contribution of T helper 9 (TH9) cells to both effective immunity and immunopathological disease, and propose that TH9 cells could be targeted for the treatment of allergic and autoimmune disease. [Nat Rev Immunol] Abstract