NBRP Fundamental Technologies Upgrading Program Project's Progress

Rats

Tadao Serikawa Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University

Project Period

FY2010–2011

Overview

The National BioResource Project – Rat (NBRP-Rat) is one of the core rat resource facilities in the world. In this project, sperm and embryos have been preserved to maintain rat resources, while present reports concern the establishment of rat ES and iPS cells. Moreover, mutant strains and knockout strains have also been produced using ethylnitrosourea (ENU) and zinc finger nucleases (ZFN) respectively. Research using these new rat strains and those maintained in NBRP-Rat will increase rapidly in the near future. For this reason, efficient technologies for 1) the cryopreservation of sperm that can be used for in-vitro fertilization and 2) freeze-dried sperm that can be preserved long term at room temperature should be established. This program targets improved rat sperm preservation methods via the collaboration of Kyoto University and Azabu University. The results of this program will facilitate the efficient production of offspring using cryopreserved sperm maintained at NBRP-Rat, and make the preservationand transportation of freeze-dried sperm safer and simpler without liquid nitrogen.

Terms of Use
|
Contact us
Copyright : Each organization participating in NBRP. All Rights Reserved. We recommend "Internet Explorer7.0" and higher, "FireFox4.0" and higher or "Safari5.0" browsers for optimal viewing.Feel free to link to any of the pages.