With exceptional contributions from an international array of leading experts in academia, government and industry, Biostatistics in Clinical Trials has been designed to complement existing texts by providing extensive, up-to-date coverage and introducing the reader to the research literature.

Featuring articles from the prestigious Encyclopedia of Biostatistics, many of which have been fully revised and updated to reflect recent developments in the field, Biostatistics in Clinical Trials also includes up to 25% newly commissioned material reflecting the latest thinking in:

Features an extensive and comprehensive range of topics that relate to the design, conduct, and analysis of clinical trials. In addition, articles have been included that discuss biostatistical aspects of clinical trials such as societies, textbooks, publication guides, historical perspectives, particular trials and collaborative trial groups.

* Includes concise definitions and introductions to numerous concepts found in current literature
* Discusses the software and textbooks available
* Uses extensive cross-references helping to facilitate further research and enabling the reader to locate definitions and related concepts
* Provides bibliographic citations to serve as signposts to assist researchers in further investigations of the topic

An essential single volume reference for practitioners and researchers...

Academics and practitioners from various disciplines and settings, such as universities, the pharmaceutical industry and clinical research organizations, will find this a comprehensive compendium of information on all aspects of clinical trials.

Essential Medical Statistics is a classic amongst medical statisticians. An introductory textbook, it presents statistics with a clarity and logic that will demystify the subject, while providing a comprehensive coverage of advanced as well as basic methods. Book overviewThe second edition of Essential Medical Statistics has been comprehensively revised and updated to include modern statistical methods and modern approaches to statistical analysis, while retaining the approachable and non-mathematical style of the first edition. The book now includes full coverage of the most commonly used regression models, multiple linear regression, logistic regression, Poisson regression and Cox regression, as well as a chapter on general issues in regression modelling. In addition, new chapters introduce more advanced topics such as meta-analysis, likelihood, bootstrapping and robust standard errors, and analysis of clustered data. Aimed at students of medical statistics, medical researchers, public health practitioners and practising clinicians using statistics in their daily work, the book is designed as both a teaching and a reference text. The format of the book is clear with highlighted formulae and worked examples, so that all concepts are presented in a simple, practical and easy-to-understand way. The second edition enhances the emphasis on choice of appropriate methods with new chapters on strategies for analysis and measures of association and impact.

Published monthly, the Journal of Clinical Epidemiology provides timely, authoritative studies developed from the interplay of clinical medicine, epidemiology, biostatistics and pharmacoepidemiology. Articles are oriented toward methodology, clinical research or both. A special section, Pharmacoepidemiology Reports, is dedicated to the rapid publication of articles on the clinical epidemiologic investigation of pharmaceutical agents.