I am using Adobe Cloud. And have downloaded Photoshop CS6. Using it locally.

It was working fine. For weeks. The application still loads without error. But if I open a file nothing happens. No error message. But no file appears. And if I try to create a new file the same thing. No error message. But no new canvas to work with. In both cases nothing appears in the layers panel.

The Help menu gives me the option of deactivating. So I am assuming it is not an activation issue.

Fireworks works fine. Illustrator works fine. Only Photoshop has this problem.

Are Photoshop and OS fully updated and have you performed the usual trouble-shooting routines (trashing prefs by keeping command-alt-shift/ctrl-alt-shift pressed while starting Photoshop after making sure all customized presets like Actions, Patterns, Brushes etc. have been saved and making a note of the Preferences you’ve changed, 3rd party plug-ins deactivation, system maintenance, cleaning caches, font validation, etc.)?

I'm sorry I should have been more clear the preference cleanup/reset I tried the very first time. I notice it started after the last PS6 update. So last night I did the following.

Uninstall Creative Cloud

Ran Creative Cloud Cleaner

Deleted all preference files in \users\documents\X\appdata

Re-installed to another drive in the system (Creative Suite)

Like clockwork I can open Photoshop without a problem the first time. If I close PS6 and re-open it I am unable to Create a New File, Open any existing graphics or PS compatible files until I reboot again. Hitting CTRL-N shows me the new file dialogue which I can't get to show up from choosing File-->New. However, once I hit enter on the dialogue it goes away but no ned file is opened.

I can also drag images into photoshop via bridge and they show up. However, they are uneditable I can't make new layers and I can't edit the file. It's like I see it in PS6 but PS6 dosesn't know it's there.

I had enough I uninstalled Creative Cloud and secure wiped the Intel 520 SSD and the wiped the RevoDrive 3 X2. Installed windows 8 clean install and re-downloaded and installed all the Creative Cloud Apps.

1. After the install was completed clicking on Photoshop CS6* causes nothing to happen. No tasks open, nothing in task manager showing photoshop opening. It's like the request just goes away.

2. Figured maybe I need the updates, opened bridge clicked on help - updates.

3. All products had updates and updated them all.

4. All updates successful except for Photoshop and DynamicLinkmanager.

Photoshop Update Failed

Adobe Photoshop 13.0.1.1

Installation failed. Error Code: U44M2P7

So then I search the forums and find the option to manually download the CS6 update from Adobe.com. I did that and still nothing.

So in Windows 7 I could open Photoshop once per reboot and work. Now in Windows 8 I can't even get it to open.

There has to be an incompatibility with either:

1. Nvidia GTX680 4GB cards

2. Nvidia WHQL Latest Drivers

I draw that conclusion because PS CS6 has worked just fine until Nvidia Updates were installed. I know in 3D Mark III the card only reports as a 2GB and they claim it's purely cosmetic reporting. It also works fine on my Quadro 5000 card in another box.

Unable to open Photoshop CS6 in Windows 8 Pro

Unable to open using program Compatibility Troubleshooter Mode: Windows 7

Unable to open images in Adobe Camera Raw or Photoshop from within Bridge. No Errors it's like the request simply disappeared.

I, too, have an EGA 680 4GB (FTW Edition) and have been having this same issue. Photoshop will not open files or create new files after being open for a while after restarting it. Is this something Adobe has to fix, or nVidia?

I have the same type of problem. The only way Photoshop CS6 will open a file is to completely shut down. When it opens up again it will only open one file,and then it goes back to the same problem. It also will not create a new canvas. When Iwas able to open the one file I tried using the brush tool.and it would just partially work. Just for the hell of it i switched my mouse and believe it or not everything went back to normal. The old mouse would work great in everything else such as Premiere etc. but not in photoshop. It was not a bettery problem in the mouse as they were new batteries, just something wrong with the mouse. I sincerely hope this works for everyone who is having this problem, as it was sooooo frustating. Let me know.

My original post here was july 12, 2013. I have found that there doesn't seem to be any one fix to this problem. I thought I'd add this post since my Photoshop now works although I cannot tell exactly what fixed it.

My computer is a PC. My problem started right after I updated CS6. I could open Photoshop (CS6), open one file, maybe be able to work on it (or not). If I could work on it if would find when I tried to open another photo file it would not open at all. I could reboot and again open one file in Photoshop. I described the problem on several forums and received nothing that helped. I tried virtually everything suggested above in this post and from other forums. All drivers were up to date. Lack of memory was not the problem. Most solutions did not work or only worked for a short while and then the problem would return. I did replace the mouse and it didn't help. I even completely reloaded Windows 7 and all my software, one thing at a time, and Photoshop worked for three days and then, having made no further changes in the computer by adding any software, etc. during those three days it again went to opening no files or opening only one and refusing to open any more until after rebooting the computer.

I contacted ADOBE again (their original suggestions had not worked) and they suggested opening msconfig, disabling all in the Startup Tab and then going to Services, clicking the Hide all Microsoft services, and then disabling all. After doing this Photoshop began to work normally which was weird because I had already tried this and it hadn't helped. This time it worked so something else must have changed somewhere. I have gradually added needed files (anti-virus, anti-malware, Google, Adobe, etc.updaters, monitor calibration software, all my Photoshop and lightroom plug-ins, Microsoft Office, etc.) and my Photoshop CS6 is still working.

I've been having the same problem. I tried everything on this thread. The reason the MSConfig tweak works is because the problem is with your permissions - the tweak is turning off services, one of which may be affecting your permissions. To restore your permissions, open a command prompt and type

I have tried every "solution" in this thread and nothing works. I have also done a lot of troubleshooting myself and nothing.

I have noticed something that I haven't seen in these threads. If you spam Ctrl+N the dialog window will eventually pop out, however clicking ok does not create a new file. It just goes away. If I spam Ctrl+N and spam click left mouse button where the OK button is once the dialong window pops up, it will eventually create a new file. However it seems to refresh every second or two. If I were to hold down left mouse and draw with my brush tool, I can only draw for maybe 1 second, then it stops drawing. If I then release left mouse the line that I drew goes away. I can however draw small lines before it refreshes, if I tap click my left mouse.

I'm worried that what I wrote might be difficult to understand. If requested, I will make a video.

Pressing the key or key combination repeatedly. By pressing Ctrl+N several times quickly, I can get the new file dialog box to appear after 3 to 4 quick presses of the key combination. Pressing the key combination slowly does not work. You have to tap Ctrl+N rapidly.

Have you tried directly contacting Adobe for help with this problem? I also had this problem, went through all suggestions on this thread and nothing helped. I contacted Adobe and within a few minutes had a solution. I know the problem is that you try a solution and then have to go back and use Photoshop to see if it helped and often it doesn't.

Here is what worked for me which doesn't mean it will work for you. MY Os iw windows 7 and I have Photoshop CS6.

I contacted ADOBE again (their original suggestions had not worked) and they suggested opening msconfig, (type in "search programs and files" box that opens when you click the Start button in bottom left corner of screen. Then disabling all in the Startup Tab and then going to Services, clicking the Hide all Microsoft services, and then disabling all. After doing this Photoshop began to work normally which was weird because I had already tried this and it hadn't helped. This time it worked so something else must have changed somewhere. I have gradually added needed files (anti-virus, anti-malware, Google, Adobe, etc.updaters, monitor calibration software, all my Photoshop and lightroom plug-ins, Microsoft Office, etc.) and my Photoshop CS6 is still working.

I have indeed tried this and no luck. I had nothing startup and no services (aside from microsoft ones, of course) and I thought it fixed it. Until about 3 hours later, then Photoshop did the exact same thing again.

I have tried almost everything to fix this, but no luck. I'm about to go as far as building a new computer. I'm so fed up with this. Contacting Adobe is useless and several threads on this forum are still unsolved.

Does Photoshop have some sort of debug mode? If I could find a way to log EVERYTHING that it's doing, that would be a huge help.

It's likely a hardware issue, Chris. I switched from Windows 7 to Vista and the problem persisted, so I switched back to 7. Photoshop was one of the first programs installed when I switched, it was even installed before many drivers. It's quite obvious that it's something else outside of Photoshop, but why is Photoshop the only program affected by this? It's also incredibly odd that the solutions vary. Some have fixed it by updating their graphics drivers, rolling back their graphics drivers, resetting windows permissions, getting a new mouse and/or keyboard, making a new user account, so on and so forth. I have tried all of those and then some. It's also strange that the problem occurs after a random amount of uptime. Sometimes it's breaks 5 minutes after booting and sometimes it's 3 hours. It's such a strange issue that I have never encountered before with any other computer or program.

Try re-installing Adobe Flash, reverting to an older video driver and/or doing a roll back with windows 7. This is not an hardware issue, it is a software issue. I do technical support and every solve for this issue has been one of the above three that I posted.