Anytime a spice product comes with a disclaimer that you have to approve, you know it's serious — and Blair's 16 Million Reserve Crystals ($545 and up) are indeed serious. Limited to a run of 999, the gold and white wax-sealed bottle holds inside a 1ml pharmaceutical grade vial packed with pure capsaicin crystal, the main active component of chili peppers. To put it another way, this is absolutely the hottest hot sauce product known to man. Handle (and eat) with care.