Brief Summary

Official Title: “Genetic Studies of Patients and Their Families With Inherited Cardiovascular and Neuromuscular Diseases.”

We are studying the genetics of human cardiovascular and neuromuscular disease. There are many different genetic regions that have been associated with the development of cardiomyopathy. An equal number of genetic regions have been associated with muscular dystrophy and there is overlap because some of the identical genes, when mutated, produce both cardiomyopathy and muscular dystrophy. We are working to identify genes and gene mutations associated with cardiomyopathy, arrhythmias and muscular dystrophy. We propose to screen these samples for mutations in genes known to be involved in these disorders.

Study Type: Observational

Study Design: Observational Model: Family-Based

Study Primary Completion Date: January 2025

Interventions Used in this Clinical Trial

Procedure: Blood draw (genetic testing)

Blood draw (genetic testing)

Outcome Measures for this Clinical Trial

Primary Measures

Identification of genetic causes of cardiomyopathy

Time Frame: unlimitedSafety Issue?: No

Criteria for Participation in this Clinical Trial

Inclusion Criteria

Patients of all ages will be considered for the study. In particular, families with more than one affected relative will be sought.

Exclusion Criteria

Subjects without a suspected inherited cardiovascular or neuromuscular disorder will be excluded from this study.

Additional Information on this Clinical Trial

Link to the current ClinicalTrials.gov record. – http://clinicaltrials.gov/show/NCT00138931

Study ID Number: 8249

ClinicalTrials.gov Identifier: NCT00138931

Health Authority: United States: Institutional Review Board

Source

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