Let Dr. Hickey help you enhance your hearing and maintain your independence. Don't wait any longer to be a part of the conversation. Call to set up your appointment and be on your way to better hearing in no time.

Let Dr. Hickey help you enhance your hearing and maintain your independence. Don't wait any longer to be a part of the conversation. Call to set up your appointment and be on your way to better hearing in no time.

Let Dr. Hickey help you enhance your hearing and maintain your independence. Don't wait any longer to be a part of the conversation. Call to set up your appointment and be on your way to better hearing in no time.

Study Examines SNHL Treatment Using Umbilical Cord Blood

CBR® (Cord Blood Registry®), the world's largest newborn stem cell company, has announced the publication of the results of the first clinical trial evaluating the use of autologous umbilical cord blood in children with acquired sensorineural hearing loss (SNHL).

Co-principal investigators, Dr. James Baumgartner, MD and Pediatric Surgeon at Florida Hospital for Children, and Linda Baumgartner, Certified Auditory Verbal Therapist at Little HEARoes and Clarke Schools for Hearing and Speech, performed the study at the Florida Hospital for Children. The study was published in August 2018 by the Journal of Audiology & Otology, and institutional funding was provided solely by CBR, a California Cryobank Company.

As part of their commitment to help advance the science of newborn stem cells, CBR funded this phase 1 pilot study to assess the safety and preliminary efficacy of infusions of autologous umbilical cord blood in 11 children with acquired SNHL.

The study demonstrated that the cord blood infusions were safe, feasible, and well tolerated. In addition, 45% of participants showed improvements on Auditory Brainstem Response (ABR) after their infusion.

"We found a statistically significant improvement in a measure of hearing based on one of the tests we performed," said Dr. Baumgartner. "This may be an indication that newborn stem cells help the ear repair itself in some children with hearing loss."

The study provides the first clinical evidence in humans to support this hypothesis. Dr. Baumgartner went on to say, "Although the exact mechanism of action is unknown, unique properties of the cord blood cellular components are believed to spur regeneration of the cilia (hair) and support cells within the cochlea."

SNHL is defined as hearing loss due to damage or dysfunction of the inner ear (as opposed to other structures of the ear). This can be a result of premature birth, infections, or exposure to noise or ototoxic drugs, resulting in irreversible damage to the fragile hair cells (cilia) in the inner ear.1

Although hearing aids or cochlear implants help to improve the ability to hear in individuals who have SNHL, these current interventions don't address the underlying cause. Currently, there is no cure for SNHL.

"A child's hearing ability affects the development of language skills and future academic and social development," says Linda Baumgartner. Today, approximately 15% of children have some form of low or high frequency hearing loss, and 40% of young adults with hearing loss experience a limit in daily functioning.2,3

"These preliminary findings build on results from previous animal model studies4that demonstrated human umbilical cord blood helps restore hearing function," says Dr. Jaime Shamonki, Chief Medical Officer of CBR and California Cryobank Life Sciences. She further noted, "Given the pilot nature of this study, participants were not paired with matched controls. However, given that SNHL does not improve with age or other therapies, ABR thresholds would not be expected to improve spontaneously in these children, regardless of concurrent use of hearing aids or speech therapy. We have good reason to believe that cord blood stem cells played a role in improving ABR in these children."

"We're excited to see what future research may hold," said Heather Brown, Vice President of Scientific & Medical Affairs for CBR. "We hope that newborn stem cell therapies will help broaden the options available for children with acquired hearing loss and other conditions. Expectant parents should be made aware of the one-time opportunity to preserve their child's cord blood, as it is a pristine source of hematopoietic stem cells as well as other potentially useful cells."

For the past 30 years, cord blood stem cells have been used to rebuild healthy blood and immune systems as part of a stem cell transplant. They've helped more than 40,000 patients worldwide with certain cancers, blood disorders, and immune disorders as part of a stem cell transplant, from both donated and privately banked cord blood.5 It's also being researched for its potential to be used for conditions like autism and cerebral palsy.

As an industry leader with over 800,000 stored samples, CBR has funded multiple FDA-regulated clinical trials for conditions that have no cure today. Through their Family Health Registry™ (FHR) community, client families are the first to know about clinical trials that could potentially help their immediate family. The 11 children who participated in this study are all CBR clients whose cord blood was preserved at the time of birth.

Hearing Survey

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Hearing Survey

Please answer the question below to the best of your ability. After you choose your answer, the next question will appear. At the end of the survey, you will be provided with a score, and you may send this score to us so we may discuss any hearing loss issues you are having.

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Are there situations in which you find it difficult to hear clearly?

Do you have to strain to understand conversations?

Do you have a problem hearing over the telephone?

Do you have trouble following a conversation when two or more people are talking at the same time?

Do you have trouble hearing conversations in a noisy background such as a restaurant or a group gathering?

Do you have dizziness, pain, or ringing in your ears?

Do family members or coworkers remark about you missing what has been said?

Do people complain that you turn the TV volume up too high?

Do you find it hard to hear someone when they talk in a soft voice or whisper?

Do you find understanding women and children particularly challenging?

You are not experiencing common signs of hearing loss. However, if you suspect you may have hearing loss or are experiencing other symptoms not listed here, please contact our office for a consultation.

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Your responses indicate that you are experiencing common signs of a hearing loss. We recommend that you contact us to set up an appointment for a hearing test.

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