I.V. Ozone

Dr. John Gonino

What is ozone? Ozone is three molecules of oxygen, O3, Instead of the usual way that oxygen exists in nature, which is O2. It was first discovered in 1786 and first synthesized in a German Lab in 1840. In 1873 it was discovered that when any micro-oganism, exs: viruses, bacteria, tuberculosis, diphtheria were subjected to ozone gas, they were killed.

In 1911, Dr, Noble Eberhart, head of the Departmant of Physiology of Loyola Chicago University used ozone to treat tuberculosis, anemia, pertussis, asthma, bronchitis, diabetes, gout and syphilis.

In 1961 Dr. Hans Wolff developed the major and minor auto hemotherapy techniques that we use in our office today. As you may remember from your high school biology class, the majority of energy in your body, called ATP, is produced in the mitochondria of our cells, through a process called electron transport. Oxygen is the final electron receptor in this process. Therefore, if we can increase the oxygen content of the body, this process can occur more efficiently.

Also, as you probably know, the food we eat requires enzymes to break it down so it can enter the mitochondria (and a little further upstream in the process called the krebs cycle). These enzymes are activated by NAD (Nicotinamide Adenine Dinucleotide). Once activated the NAD is reduced to NADH. More oxygen is then required to oxidize the NADH back to NAD so the process can continue.

In summary, 1.) Aging and diseases of aging are caused primarily by decreased oxygen utilization. 2.) This decrease leads to the excessive free radical production that results in degenerative disease. 3.) Decrease oxygen utilization is caused by both pre-mitochondrial (exs: too much sugar in the diet) and mitochondrial (exs: heavy metal toxicity, prescription drugs) factors. 4.) Decreased oxygen utilization exerts its effects by causing a decrease in the NAD/NADH ratio. 5.) Ozone therapy is effective for so many diseases including the affirmaties of aging because it normalizes this ratio.

What is the utility of ozone therapy? Where can it be found useful?

I was trained by Frank Shallenberger M.D. who has used ozone therapy for over 20 years. He recommends it for many different things but he has seen the best results with: Heart Disease/Coronary Artery Disease , including reperfusion after heart attack, liver disease (Ozone therapy has a stimulatory effect on liver cell regeneration), Cancer (Ozone selectively increases the anti- oxidant enzyme activity in healthy cells, protecting them against the side effects of chemotherapy and radiation, decreases resistance to chemo.), *** Induces anti- cancer cytokines: Tumor Necrosis Factor, Interferon, and Interleukin2, **directly kills cancer cells , may normalize “marginal” cancer cells by stimulating pyuvate -> Acetyl Co A conversion -> more ATP production by marginal cells making them more likely to heal, may stimulate apoptosis

(programmed cell death by cancer cell) Macular degeneration, chronic infections including herpes, dental infections, and MRSA along with antibiotics. Other places that he has seen it work, although not to as great as an extent as the above are: claudication/peripheral vascular disease, chronic fatigue syndrome, fungal infections, ulcerative colitis, and various types of skin infection.

“Anti –aging” is a popular term these days. I’m not a big fan of the term, but I absolutely believe that it is possible to slow down the aging process. Remember, the better we utilize oxygen, the slower our bodies’ age. We preserve our mitochondria and buffer free radicals with healthy enzymes, most specifically glutathione peroxidase, superoxide dismutase, and catalase. The fact that you have access to IV glutathione and IV superoxide dismutase in our office is obviously a plus for you, but these enzymes can also be up – regulated by : exercise, iv ozone, riboflavin ( Vit B 2) , Methyl B12, Vitamin B6, L-Methylfolate, Manganese, copper, zinc, iron, selenium, N-acetyl –cysteine, Vitamin C, Alpha Lipoic Acid , and Coenzyme Q 10.

Lastly, is it safe? A study was done in 1982 to assess the safety of the treatment we do which is called MAH; short for Major Autohemotherapy. The complication rate is 1 in 150,000 treatments which are usually either infection or redness and swelling, or inflammation in the vein used for administration. To date, there are no reported deaths.

Though not FDA approved, I trust Dr. Shallenberger’s experience and patient case histories. I would like to close with a patient, who was treated with IV ozone for infection with Ebola virus in Sierra Leone in December, 2014. As you are probably aware, there are typically 2 fates a person will have when infected with Ebola virus. 60% of patients infected will die. The other 40% that survive going through 7-10 days of living hell. When the patient in Sierra Leone was treated with major autohemotherapy, he recovered in 2 days with no subsequent issue. Obviously, as only a single case, we can’t draw any conclusions, but if I get infected with Ebola, please give me MAH every day!

What does Major Autohemotherapy involve? To do the therapy, our staff will first obtain intravenous access. After that, 100ml of your blood (1/42nd of your total volume) is withdrawn from your body and mixed with 100ml of normal saline, then 200ml of ozone is added to the bag until the blood brightens up to a crimson red. This will usually take about 3 min. Then, the entire mixture is re-infused into the body at 20-40 drops per min. The whole process will take 40-60 minutes. Thank you for your attention and you willingness to consider intravenous ozone therapy.

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News & Events

On December 18, 2018 and Jan. 3, 2019 Dr. Gonino will be on Doug Kaufmann's Know the Cause TV show. Speaking about health, wellness, and some amazing miracles weve seen here at the practice. Tune in and share the news! Watch on www.knowthecause.com, Know the Cause Youtube, or on certain TV channels. Connect to website for more info on TV stations.

Join us LIVE in Dallas July 28, 2018 or purchase the LIVESTREAM option that you can replay ANYTIME, ANYWHERE.

On Saturday, July 28, we bring together NINE health experts in Dallas, to inspire you to ReThink your HEALTH.

It’s a not-to-miss, eye-opening live event that will educate & empower you to take BACK YOUR HEALTH from a medical/pharmaceutical industry that makes money keeping you and your family SICK -- not HEALTHY.

Join us in a march to raise awareness about why our children are so sick! Dr. Gonino will be speaking at the rally at Dallas City Hall around 10am and later at the Health Summit at the Hotel Intercontinental approx. 1:30. To learn more visit their websites at www.childrensmarchforhumanity.org and www.learntherisk.org

Don't forget!!!- Dr Sinatra is scheduled to be Linda and my guest on our radio show on Nov 18. The show's first aire date is Oct 7 , 3pm Central time. It will run on consecutive Fridays for 13 weeks. In addition to Dr Sinatra , we will also have the following guests: Doug Kaufmann host of the television series Know The Cause, Dr Richard Becker , co- host ( wife Cindy) of the television series , " Your Health Matters" , and Erin Elizabeth of Health Nut News , which has over 1 million followers to date. As we add more guests we will keep you posted. To join the show live, log in to VoiceAmerica.com . Linda and I and all of our staff appreciate your support so much.

Dr. Gonino and Linda attended the Dr. Frank Shallenberger Ozone Therapy Intensive training in April of 2015. Learning the importance and effectiveness of Ozone Therapy in its' many forms. We now have instituted IV Ozone therapy into our regimen and it is proving successful in many patients especially those with Degenerative Diseases, Heart Disease/Coronary Artery Disease and liver disease.