Marche’s winemaking heritage spans thousands of years and has been influenced, among others, by the Etruscans, Romans and Lombards. The presence of these various cultures goes a long way to explaining the breadth of vinicultural tradition and wine styles in the region.

Marche has a number of terroirs that are extremely well suited to the cultivation of vines, particularly among the rolling coastal hills such as those around Ancona. Due to the influences of the Apennines, the Adriatic and the region's rivers (the Metauro, Potenza, Tronto and Nera), there are various climates at work in Marche, giving wine producers both warm and cool viticultural zones to utilize. Calcareous, clay and limestone-rich soils contribute to the distinctive terroir, and vary according to the region's distinctive topography.