Globular Proteins

Globular Proteins

crystalline proteins that are easily soluble in water or weak saline solutions; their molecules are close to spherical (the ratio of the sphere’s axes does not exceed 5). Such a molecular structure is determined by the spiralization of the peptide chain and by its dense packing, which is due to the tertiary structure. Many globular proteins exhibit enzymatic activity. Globulins, myoglobin, and ribonuclease are among the important globular proteins. Some proteins, such as actin, exist in both globular and elongated fibrillar form.

Whey protein is a mixture of globular proteins isolated from whey, the liquid material created as a byproduct of cheese production -the watery portion of milk that separates from the curds when making cheese.

As to the stability issue for globular proteins under the impact of different additives, including RTILs, it can be adequately approached by the method of differential scanning calorimetry (DSC) [4, 5, 8-11,13-17, 23-26].

Results of this project will boost the knowledge related to the first misfolding events leading to AT3 pathological aggregation as well as our understanding on subtle misfolding events triggering protein aggregation of folded globular proteins.

Lorient et al, [34] note that unfolding of the [beta]-Iactoglobuline and [alpha]-lactalbumin by reduction and carboxymethylation S-S bridges also increases the flexibility of the molecules, while thermal denaturation does not seem to significant effects unless the proteins precipitate which case the mobility is greatly reduced; these observations on mobility and flexibility can be easily connected not only to the structure more or less deshirred molecules, but also because the interfacial behavior surfactant properties are best when mobility is higher (flexible proteins such as casein and globular proteins deshirred, pHi, presence of salts, etc.

Their topics include what a polymer molecule looks like, polymers in nature, the physics of high elasticity, globular proteins and folding, the dynamics of polymer fluids, and the mathematics of fractals as complicated polymer structures.

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