Also you can insert them in a BindingList<Tuple<string, string, string>> and bind the ListBox to that list by assigning the binding list to DataSource of ListBox. This way, you can simply add or remove items to the binding list, and the changes will be shown immediately in ListBox.

Note:
If you want to save them in database, consider using a DataTable or an entity framework model class, then you can simply save them to database.

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