Virtual screening is the process that determines whether the library of molecules generated using computational techniques meets a number of criteria to become likely drug candidates. Accurate and a priori screening is of essence to take the critical ‘go – no go’ decisions regarding the newly designed molecules.

VLife offers Virtual Screening services to help drug discovery companies and discovery research scientists arrive at the correct decisions on which compounds from their libraries are worthy of further investment in terms of synthesis and experimental validation. Our expert scientists will put to use the latest technologies available to rank or filter a set of molecules based on the customer specified criteria.

VLife can assist you by utilizing a variety of screening filters depending upon the extent of structure and activity data that is available. Our scientists may employ either a ligand based screening approach or a structure based screening approach or both to provide you with the best scoring of the molecules in your library. Our virtual screening services could include a QSAR predicted activity based screening, pharmacophoric feature based screening or docking based screening followed by filtering using an extended Lipinski rule of five. The step wise screening process helps to eliminate potentially unfavorable molecules at an early stage.

Where VLife can help

Some other representative activities where our Knowledge Services can help you are:

Our expertise in computational discoverySuccess with computation technology requires awareness of not only its strengths but also of the areas where it needs augmentation from other approaches. Being developers of computational technologies, we have proved our expertise by creating IP in 3 NCE classes and 7 new indication discoveries.

Wide diversity of experienceWe cater to a variety of sectors and within them, a diversity of areas. e.g. in pharmaceuticals, we have successfully delivered discovery projects in oncology, anti-fungal, diabetes, CNS etc.

State-of-art technology portfolioClients benefit from the whole range of VLife's technologies having validated algorithms, published innovations and efficient workflows which are accessible to clients through VLife services.

In-house custom development skillsGeneric technologies sometimes are inadequate or inefficient in complex research. For such needs, our in-house team has skills to develop custom technologies ensuring reliable research.