Now we have a space flight side effects list. It will change in the future for sure. It’s time to have 1/6G and 1/3G list too as soon as possible. Better sooner than latter. Earth’s plants and animals are designed to 1G. So simple logic says 1/6G and 1/3G will have impact as well. We just don’t know how big the list will be yet.
Based on that knowledge our plan to build a base or colony on Moon or Mars maybe altered greatly. So obviously we need to build moon, mars bases to gather that knowledge.