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Serine endopeptidases that will digest various components of extracellular matrix such as elastin and collagen type IV. A range of elastases are known; the pancreatic elastase (EC 3.4.21.36, formerly EC 3.4.4.7) is perhaps the commonest; the elastase of neutrophil granules differs, as does that from macrophages. It is inhibited by α1-protease inhibitor of plasma.