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The StorCenter PX Series is based on Iomega's LifeLine OS and includes four and six bay desktop and four bay rackmount models and are Iomega's first to be offered in diskless configurations. 7200 rpm SATA HDDs and SSD drives are available from Iomega or may be purchased from an approved vendor list. Drives mount on a drive carrier that can accommodate 2.5-inch and 3.5 inch HDD or SSD drives.

The px4-300d and px6-300d desktops are powered by Intel D525 Atom CPUs, while the rackmount px4-300r runs on an Intel Celeron CPU. All have 2 GB of RAM, dual Gigabit Ethernet LAN interfaces and support up to 3 TB SATA drives configurable into RAID 0, 1, 10, 5, 5+1 (hot spare) and 6 volumes, with automatic RAID rebuild and hot swap.