Early Growth Genetics Consortium

Maternal GWAS of Offspring Birthweight Summary Data (2018)

We are releasing the summary data from our maternal genome-wide meta-analyses of offspring birth weight, combining data from the EGG consortium and the first release of the UK Biobank genetics data (released May 2015).

Data were imputed up to the reference panels from Hapmap Phase 2 (EGG Consortium studies) or combined 1000G and UK10K Project (UK Biobank). Birth weight was z-score transformed. The association between each variant and birth weight was tested separately using a linear regression model, with adjustment for offspring sex and gestational week (both where available) and study-specific ancestry covariates.