Ok, for all that dont know...this doesnt mean "whats up" that would be "whats good" whats really good is reffering to a dude tryin to get a chicky..like some other dude defined it "a pick up line" so to speak...but its more like after youve met the chick and you dont wanna be pusst footin around shit...

"damn ma, i know we been kickin for a minute but whats really good with us shorty?"