Product Details

Complete skin care system specially formulated for normal to dry skin to help correct hyperpigmentation, such as dark spots and melasma, and transform the appearance of aging skin. Valid prescription required. Please see Important Safety Information below and Prescribing Information.

Kit Includes:

Gentle Cleanser

Toner

Clear

Exfoderm®

Blender®

Obagi Hydrate®

Sun Shield Matte Broad Spectrum

Not available in select states including MA, MT, NH, NY, and TX, due to state regulations regarding the ability of physicians to dispense prescription drug products in their offices. For an effective, cosmetic skin-brightening option, learn about the Obagi Nu-Derm Fx™ System.

Effective prescription 4% hydroquinone that helps correct hyperpigmentation, such as dark spots, sun spots, age spots, melasma, and other types of discoloration, for a healthier-looking, more even skin tone.*Valid prescription required. Please see Important Safety Information below and Prescribing Information.

Active Ingredient:4% Hydroquinone

*Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people.

Not available in select states including MA, MT, NH, NY, and TX, due to state regulations regarding the ability of physicians to dispense prescription drug products in their offices. For an effective, cosmetic skin-brightening option, learn about the Obagi Nu-Derm Fx™ System.

Exfoderm®

A lightweight lotion that helps exfoliate the top layer of the skin, removing dull, old skin cells, while revealing new skin cells for a brighter complexion.

Key Ingredients:
6% Phytic Acid

Blender®

A unique formula containing prescription 4% hydroquinone for the gradual lightening of hyperpigmentation, such as dark spots, sun spots, age spots, melasma, and other types of discoloration.*Valid prescription required. Please see Important Safety Information below and Prescribing Information.

Active Ingredient:4% Hydroquinone

*Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people.

Not available in select states including MA, MT, NH, NY, and TX, due to state regulations regarding the ability of physicians to dispense prescription drug products in their offices. For an effective, cosmetic skin-brightening option, learn about the Obagi Nu-Derm Fx™ System.

Obagi Hydrate®

A moisturizing cream to be used as needed to soothe areas of dry, flaky skin.

A sunscreen that combines UVA and UVB protection in an elegant matte finish that is non-comedogenic, allergy tested, and dermatologist tested. Sheer, PABA-free, and fragrance-free for all skin types.

Active Ingredients:
10.5% Zinc Oxide, 7.5% Octinoxate

Nu-Derm System for Normal to Oily Skin

Complete skin care system specially formulated for normal to oily skin to help correct hyperpigmentation, such as dark spots and melasma, and transform the appearance of aging skin. Valid prescription required. Please see Important Safety Information below and Prescribing Information.

Kit Includes:

Foaming Gel

Toner

Clear

Exfoderm® Forte

Blender®

Obagi Hydrate®

Sun Shield Matte Broad Spectrum SPF 50

Not available in select states including MA, MT, NH, NY, and TX, due to state regulations regarding the ability of physicians to dispense prescription drug products in their offices. For an effective, cosmetic skin-brightening option, learn about the Obagi Nu-Derm Fx™ System.

Effective prescription 4% hydroquinone that helps correct hyperpigmentation, such as dark spots, sun spots, age spots, melasma, and other types of discoloration, for a healthier-looking, more even skin tone.*Valid prescription required. Please see Important Safety Information below and Prescribing Information.

Active Ingredient:4% Hydroquinone

*Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people.

Not available in select states including MA, MT, NH, NY, and TX, due to state regulations regarding the ability of physicians to dispense prescription drug products in their offices. For an effective, cosmetic skin-brightening option, learn about the Obagi Nu-Derm Fx™ System.

Exfoderm® Forte

A lightweight lotion that helps exfoliate the top layer of the skin, removing dull, old skin cells, while revealing new skin cells for a brighter complexion.

*Sunburn Alert: This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.

Key Ingredients:
6% Glycolic acid, 4% Lactic acid

Blender®

A unique formula containing prescription 4% hydroquinone for the gradual lightening of hyperpigmentation, such as dark spots, sun spots, age spots, melasma, and other types of discoloration.*Valid prescription required. Please see Important Safety Information below and Prescribing Information.

Active Ingredient:4% Hydroquinone

*Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people.

Not available in select states including MA, MT, NH, NY, and TX, due to state regulations regarding the ability of physicians to dispense prescription drug products in their offices. For an effective, cosmetic skin-brightening option, learn about the Obagi Nu-Derm Fx™ System.

Obagi Hydrate®

A moisturizing cream to be used as needed to soothe areas of dry, flaky skin.

*Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people.

Not available in select states including MA, MT, NH, NY, and TX, due to state regulations regarding the ability of physicians to dispense prescription drug products in their offices.

Obagi Nu-Derm® System

Complete skin care system specially formulated for normal to oily skin to help correct hyperpigmentation, such as dark spots and melasma, and transform the appearance of aging skin. Valid prescription required. Please see Important Safety Information below and Prescribing Information.

Real Results

The safety and effectiveness of the system has not been evaluated beyond 24 weeks. If there is no improvement after 12 weeks, please discontinue use of the system. See below for Important Safety Information.

Obagi Nu-Derm System with 0.025% Tretinoin Cream Before & After†

BEFORE

WEEK 24

Photos have not been retouched. Results may vary.

Obagi Nu-Derm System with 0.025% Tretinoin Cream Before & After†

BEFORE

WEEK 24

Photos have not been retouched. Results may vary.

Obagi Nu-Derm System with 0.025% Tretinoin Cream Before & After†

BEFORE

WEEK 24

Photos have not been retouched. Results may vary.

Obagi Nu-Derm System with 0.1% Tretinoin Cream Before & After†

BEFORE

WEEK 24

Photos have not been retouched. Results may vary.

Obagi Nu-Derm System with 1.0% Retinol* Before & After‡

BEFORE

WEEK 24

Photos have not been retouched. Results may vary.

Obagi Nu-Derm System with 1.0% Retinol* Before & After‡

BEFORE

WEEK 24

Photos have not been retouched. Results may vary.

Obagi Nu-Derm System with 1.0% Retinol* Before & After‡

BEFORE

WEEK 24

Photos have not been retouched. Results may vary.

Obagi Nu-Derm System with 1.0% Retinol* Before & After‡

BEFORE

WEEK 24

Photos have not been retouched. Results may vary.

Obagi Nu-Derm System with 1.0% Retinol* Before & After‡

BEFORE

WEEK 24

Photos have not been retouched. Results may vary.

*Retinol 1.0% sold separately.

†Study results for a 24-week evaluation of the efficacy and tolerability of twice-daily use of the Obagi Nu-Derm Normal to Oily System with 0.025% tretinoin cream, N=20

‡Study results for a 24-week evaluation of the efficacy and tolerability of twice-daily use of the Obagi Nu-Derm Normal to Oily System with 1.0% retinol, N=33

Tretinoin Indication and Important Safety Information

Indication

Tretinoin Gel (0.05%) and Cream (0.1%, 0.05% and 0.025%) are used in the topical treatment of acne vulgaris.

Tretinoin is for use on the skin only. Do not get it in your mouth, eyes, vagina or the corners of your nose.

Important Safety Information

While using tretinoin, you should:

minimize exposure to the sun and to extreme cold or wind. Avoid sunlamps, tanning beds and ultraviolet light.

use a sunscreen with a SPF of at least 15, wear protective clothing and wide-brimmed hat

stop using tretinoin if you get a sunburn

avoid washing your skin too often, scrubbing the affected skin, or using other products with a drying effect, including other products containing tretinoin, unless recommended by your healthcare provider

Before using tretinoin, tell your healthcare provider if you:

are allergic to fish (gel only). Contact your healthcare provider if you develop itching or rash while using tretinoin gel.

have a skin condition called eczema

have a sunburn

are pregnant or breastfeeding, think you are pregnant, or plan to become pregnant or to breastfeed

What are the possible side effects of tretinoin?

skin dryness, burning, redness, excessive flaking or peeling. If you develop these symptoms your healthcare provider may tell you to stop using it for a while, decrease the number of applications, or stop using it completely.

Tell your healthcare provider about any side effect that bothers you or does not go away.

The safety and efficacy of Tretinoin have not been established in the treatment of patients younger than 10 years of age (Gel) or 12 years of age (Cream), or in pregnant or nursing women.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Success Stories

Changing Skin. Changing Lives.

See what real people have to say about their experiences with Obagi Nu-Derm.

The testimonials presented are based on these users’ experiences; and individual results may vary.

Meet Corinne

Watch Corinne’s video as she describes how Obagi Nu-Derm® helps her keep signs of aging at bay. Using the system helped Corinne reduce hyperpigmentation, uneven skin tone, and dark spots. With her skin tone and confidence back, it’s no wonder she was selected to be one of our 2013 Obagi Ambassadors.

See Important Safety Information about the Obagi Nu-Derm System below.

Meet Kristen

Hear Kristen’s story and watch her transformation as she describes how she tried everything to achieve healthy-looking skin without success, until she discovered Nu-Derm.

Meet Wendy

Watch Wendy’s transformation on Nu-Derm as she made a commitment to her skin to reverse the appearance of skin damage that has occurred over the years.

Hear what others are saying about Obagi Nu-Derm:

“We have used the Obagi Nu-Derm skin care system for 17 years, and I have not found any other system that is comparable to the excellent results for rejuvenating and maintaining healthy skin.”

Jody Comstock, MD
Founder/Physician
Skin Spectrum, Tucson, AZ

“I really didn’t like the texture of my skin, my pore size, and I had a lot of hyperpigmentation. I was a little intimidated to have to use so many products and have to buy into some sort of system. I was skeptical. But all I can say is WOW! What a transformation.”

Paige
Orinda, CA

“I started the Obagi [Nu-Derm] System about 2 weeks ago to improve melasma on my face after my dermatologist recommended that I try it.

“WOW! In only 2 weeks, most of my melasma has improved and the really tough spots I've had for years are noticeably faded!* I am so delighted with your product! Even the redness and peeling (which I was warned ahead of time would happen) were very manageable.

“Some women in my office approached me the other day to ask what I was doing to my skin because it looked so smooth and radiant. I was floored! Again, thank you.”

Christine
Bedford, NH

*Results may vary.

The safety and effectiveness of the Nu-Derm System beyond 24 weeks of use have not been established. If no improvement is seen after 3 months of treatment, use of this product should be discontinued.

Important Safety Information for Obagi Nu-Derm Clear, Blender® and Sunfader

(contains 4% hydroquinone)

CONTRAINDICATIONS:
People with prior history of sensitivity or allergic reaction to this product or any of its ingredients should not use it. The safety of topical hydroquinone use during pregnancy or in children (12 years and under) has not been established.

WARNINGS:
Avoid contact with eyes, nose, mouth, or lips. In case of accidental contact, patient should rinse eyes, nose, mouth, or lips with water and contact physician.

Sunscreen use is an essential aspect of hydroquinone therapy because even minimal sunlight exposure sustains melanocytic activity.

Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people.

PRECAUTIONS (ALSO SEE WARNINGS):
Treatment should be limited to relatively small areas of the body at one time since some patients experience a transient skin reddening and a mild burning sensation, which does not preclude treatment.

Pregnancy Category C: Animal reproduction studies have not been conducted with topical hydroquinone. It is also not known whether hydroquinone can cause fetal harm when used topically on a pregnant woman or affect reproductive capacity. It is not known to what degree, if any, topical hydroquinone is absorbed systemically. Topical hydroquinone should be used on pregnant women only when clearly indicated.

Nursing Mothers: It is not known whether topical hydroquinone is absorbed or excreted in human milk. Caution is advised when topical hydroquinone is used by a nursing mother.

Pediatric Usage: Safety and effectiveness in children below the age of 12 years have not been established.

Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

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Obagi Systems and Products are physician-dispensed and should be used only under the guidance of your skin care physician. Please be advised that certain products have limited distribution and may not be available in your area. Please contact your Obagi skin care physician for more information.

Important Safety Information for Obagi Nu-Derm Clear and Blender®

(contains 4% hydroquinone)

CONTRAINDICATIONS:
People with prior history of sensitivity or allergic reaction to this product or any of its ingredients should not use it. The safety of topical hydroquinone use during pregnancy or in children (12 years and under) has not been established.

WARNINGS:
Avoid contact with eyes, nose, mouth, or lips. In case of accidental contact, patient should rinse eyes, nose, mouth, or lips with water and contact physician.

Sunscreen use is an essential aspect of hydroquinone therapy because even minimal sunlight exposure sustains melanocytic activity.

Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people.

PRECAUTIONS (ALSO SEE WARNINGS):
Treatment should be limited to relatively small areas of the body at one time since some patients experience a transient skin reddening and a mild burning sensation, which does not preclude treatment.

Pregnancy Category C: Animal reproduction studies have not been conducted with topical hydroquinone. It is also not known whether hydroquinone can cause fetal harm when used topically on a pregnant woman or affect reproductive capacity. It is not known to what degree, if any, topical hydroquinone is absorbed systemically. Topical hydroquinone should be used on pregnant women only when clearly indicated.

Nursing Mothers: It is not known whether topical hydroquinone is absorbed or excreted in human milk. Caution is advised when topical hydroquinone is used by a nursing mother.

Pediatric Usage: Safety and effectiveness in children below the age of 12 years have not been established.

Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

CONTRAINDICATIONS:
People with prior history of sensitivity or allergic reaction to this product or any of its ingredients should not use it. The safety of topical hydroquinone use during pregnancy or in children (12 years and under) has not been established.

WARNINGS:
Avoid contact with eyes, nose, mouth, or lips. In case of accidental contact, patient should rinse eyes, nose, mouth, or lips with water and contact physician.

Sunscreen use is an essential aspect of hydroquinone therapy because even minimal sunlight exposure sustains melanocytic activity.

Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people.

PRECAUTIONS (ALSO SEE WARNINGS):
Treatment should be limited to relatively small areas of the body at one time since some patients experience a transient skin reddening and a mild burning sensation, which does not preclude treatment.

Pregnancy Category C: Animal reproduction studies have not been conducted with topical hydroquinone. It is also not known whether hydroquinone can cause fetal harm when used topically on a pregnant woman or affect reproductive capacity. It is not known to what degree, if any, topical hydroquinone is absorbed systemically. Topical hydroquinone should be used on pregnant women only when clearly indicated.

Nursing Mothers: It is not known whether topical hydroquinone is absorbed or excreted in human milk. Caution is advised when topical hydroquinone is used by a nursing mother.

Pediatric Usage: Safety and effectiveness in children below the age of 12 years have not been established.

Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

CONTRAINDICATIONS:
People with prior history of sensitivity or allergic reaction to this product or any of its ingredients should not use it. The safety of topical hydroquinone use during pregnancy or in children (12 years and under) has not been established.

WARNINGS:
Avoid contact with eyes, nose, mouth, or lips. In case of accidental contact, patient should rinse eyes, nose, mouth, or lips with water and contact physician.

Sunscreen use is an essential aspect of hydroquinone therapy because even minimal sunlight exposure sustains melanocytic activity.

Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people.

PRECAUTIONS (ALSO SEE WARNINGS):
Treatment should be limited to relatively small areas of the body at one time since some patients experience a transient skin reddening and a mild burning sensation, which does not preclude treatment.

Pregnancy Category C: Animal reproduction studies have not been conducted with topical hydroquinone. It is also not known whether hydroquinone can cause fetal harm when used topically on a pregnant woman or affect reproductive capacity. It is not known to what degree, if any, topical hydroquinone is absorbed systemically. Topical hydroquinone should be used on pregnant women only when clearly indicated.

Nursing Mothers: It is not known whether topical hydroquinone is absorbed or excreted in human milk. Caution is advised when topical hydroquinone is used by a nursing mother.

Pediatric Usage: Safety and effectiveness in children below the age of 12 years have not been established.

Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.