Ted Kennedy's life's work will be the backdrop for the opening of the Edward M. Kennedy Institute for the United States Senate, where President Obama will deliver a speech. Ted Kennedy Jr. joins to talk about his father's legacy. watch

The deadline for the Iran nuclear negotiations is just days away, but an agreement still does not seem to be forthcoming. Meanwhile, the rhetoric and criticism in Washington of how the Obama administration is handling the chaotic situation in the Arab... watch

How would Hillary Clinton’s team utilize Bill Clinton on the presidential campaign trail this time around? Rick Ungar, Jessica Taylor and Robert George discuss what Bill’s role could be as well as the results of the New Hampshire tie auction, earth hour c watch

There are now calls for the NCAA to move its signature Final Four game out of Indiana, after backlash to a religious freedom law signed by Gov. Mike Pence, which critics say could allow discrimination against gays and lesbians. Jim Shella, political repor watch

Steve Kornacki's guests look at some of this week's headlines, from reports that a Clinton lawyer said no emails remain on her personal server, to a PAC giving up on stopping Chris Christie, to Peter King accusing Cruz supporters of harassing his staff. watch

A fight over defense spending on the Senate floor pitted three potential Republican presidential candidates against each other, exposing a deep and widening fracture in their party. Politico’s Manu Raju joins Steve Kornacki. watch

NBC’s Katy Tur reports on what investigators have found in the GermanWings co-pilot’s apartment and Capt. John Cox and the UP guests look at how a similar crash can be prevented in the United States. watch

Charges that were reported as imminent for New Jersey Senator Robert Menendez still haven't been filed. What's the delay? Steve Kornacki talks with New York Times National Correspondent Kate Zernike. watch

There might be a lot of resistance to former Florida Gov. Jeb Bush among some Republicans, but is there a candidate out there who can capitalize on it? The Washington Post’s Robert Costa joins Steve Kornacki’s panel to discuss. watch

NBC’s Ayman Mohyeldin brings some clarify to the rapidly-escalating chaos and confusion in the Middle East, and Michael Kay and ret. Col. Jack Jacobs join to examine the U.S. interests and geopolitics involved. watch