Schlosser studied American History at Princeton University and earned a graduate degree in British Imperial History from Oxford. He tried playwriting, and wrote two plays, Americans (1985) and We the People (2007).

Schlosser wrote Fast Food Nation (2001), an exposé on the unsanitary and discriminatory practices of the fast food industry. Fast Food Nation evolved from a two-part article in Rolling Stone. Schlosser helped adapt his book into a 2006 film directed by Richard Linklater. The film opened November 19, 2006. Chew On This (2006), co-written with Charles Wilson, is an adaptation of the book for younger readers. Fortune called Fast Food Nation the "Best Business Book of the Year" in 2001.[5]