Noteworthy: Dolphins quarterback Ryan Tannehill makes his return to action in the regular season after knee injuries in December 2016 and before the 2017 season. … Kenyan Drake, who has 823 yards rushing with five touchdowns in 32 career games, will assume an expanded role as Miami’s feature back. … Veteran Frank Gore, a former Coral Gables High and University of Miami standout, enters the game 76 yards shy of passing Curtis Martin for fourth place on the NFL’s all-time rushing list. … Tennessee’s Mike Vrabel, a former Patriots linebacker, makes his head-coaching debut. … Titans quarterback Marcus Mariota is navigating his third offensive scheme in four seasons due to offensive coordinator and head coaching changes. … Titans running back Derrick Henry assumes the starter role thanks to DeMarco Murray’s retirement, and will be spelled by former Patriots running back Dion Lewis. … Miami will start rookie linebacker Jerome Baker, while second-year linebacker Raekwon McMillian also makes his debut after recovering from a torn ACL suffered last year in the preseason. … Dolphins tight ends A.J. Derby and Mike Gesicki should see an increased role with starter MarQueis Gray lost for the season due to an Achilles tendon tear.