Our Institute

Molnár-Institute for applied chromatography focuses on new strategies for improving the efficiency and success of modern high performance liquid chromatography through our method development software DryLab, HPLC and software training courses, and HPLC consulting.

Founded in 1981 and located in the heart of Berlin, Germany, Molnár-Institute supports ongoing research and development at universities and corporations worldwide. Our team of chromatography specialists, led by Dr. Imre Molnár, is devoted to improving global health care and to ensuring the development of safe and effective products in the pharmaceutical, life-science, and food industries.

DryLab, our state-of-the-art software suite, supports analytical scientists in method development, optimization, trouble shooting, robustness testing, and training. Using real data from a minimal number of experimental runs, DryLab builds multi-dimensional selectivity maps depicting the interaction of the most important parameters influencing an HPLC separation. Our systematic, guided method development process reduces development time by over 50%, helps users optimize parameters based on their specific method goals, and enables easy compliance with regulatory standards (QbD), all while minimizing expensive trial-and-error approaches to method refinement.

If you’re interested in discussing how Molnár-Institute can help you streamline your method development process, please contact us.

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Chromatography Forum

Chromatography Forum is a moderated, public discussion group for questions, news, or messages for chromatographers worldwide.

Resources from LC Resources, Inc.

Dr. Imre Molnár

Imre Molnár, President of Molnár-Institute, has more than 35 years of experience in the field of HPLC. He specializes in pharmaceutical research and analysis and works with industrial and academic groups on research topics in pharmaceutical and biopolymer analysis.

Born in Budapest, Hungary, Dr. Imre Molnár studied at the University of Saarbrücken, which at the time was a "Special Research Center for Analytical Chemistry" in Germany. He received his PhD in 1975 with a thesis study on a separation technique for instable non-metallic compounds and spent the following two years as a postdoctoral fellow at the Department of Bioengineering at Yale University in New Haven, Connecticut, USA, studying with Csaba Horváth, a pioneer in the technique of "High Pressure Liquid Chromatography" (HPLC). From this collaboration, eleven papers were published, the three most import of which describe the fundamentals of "Reversed-Phase Chromatography" (RPC) — in particular, the much-cited Theory of Solvophobic Interactions.

Following his post-doctorate, Dr. Imre Molnár returned to Europe to work on the development of HPLC instrumentation, founding the Institute for Applied Chromatography in Berlin in 1981. During that time, he also started teaching Reversed-Phase Chromatography both at Free University of Berlin and at pharmaceutical companies throughout Europe.

In 1984, Dr. Imre Molnár began working with Lloyd R. Snyder, John W. Dolan, and Tom Jupille of LC Resources Inc. (Walnut Creek, CA, USA) on the development of DryLab, which is now widely used in both the pharmaceutical industry and the life science community. There are more than 180 scientific papers published on applications of DryLab, which is a software tool for modeling complex separation processes in (U)HPLC, enabling the user to minimize the number of experiments required to develop an optimized method.

Team

Dr. Imre Molnár, President

Norbert Klapczynski, Head of Software Development

Norbert Klapczynski is a software engineer and economist, and is responsible for the communication with IT-professionals. He also handles the distribution of the software for large industrial network users.