Patients who are hypersensitive to any component of this product.
Severe bradycardia, heart block greater than first degree, cardiogenic shock, refractory heart failure, sick sinus syndrome.

Presentation

Betabest AM is available as a strip of 10 tablets.

Betabest XL 25

Description

Metoprolol is a beta 1 -selective (cardio selective) adrenergic receptor blocking agent, for oral administration, available as extended release tablet. BETABESTT-XL has been formulated to provide a controlled and predictable release of metoprolol for once daily administration.

Indications

Hypertension
Angina pectoris
Heart failure
Post MI

Composition

Each tablet contains:
Extended release metoprolol succinate - 25 mg

Dosage

Hypertension: The usual initial dosage is 50 to 100 mg daily in a single dose. The dosage may increase at weekly intervals until optimum blood pressure reduction is achieved.Angina pectoris: The usual initial dosage is 100 mg daily, given in single dose. The dosage may be gradually increased at weekly intervals until optimum clinical response has been obtainedHeart failure: The recommended starting dose of BETABEST-XL is 25 mg once daily for two weeks in patients with NYHA class II heart failure.

Severe bradycardia, Heart block greater than first degree, Cardiogenic shock Refractory heart failure, Sick sinus syndrome (unless a permanent pacemaker is in place), Hypersensitivity to any component of this product.

Presentation

Betabest XL is available as a strip of 10 tablets.

Betabest XL 50

Description

Metoprolol is a beta 1 -selective (cardio selective) adrenergic receptor blocking agent, for oral administration, available as extended release tablet. BETABESTT-XL has been formulated to provide a controlled and predictable release of metoprolol for once daily administration.

Indications

Hypertension
Angina pectoris
Heart failure
Post MI

Composition

Each tablet contains:
Extended release metoprolol succinate - 50 mg

Dosage

Hypertension: The usual initial dosage is 50 to 100 mg daily in a single dose. The dosage may increase at weekly intervals until optimum blood pressure reduction is achieved.Angina pectoris: The usual initial dosage is 100 mg daily, given in single dose. The dosage may be gradually increased at weekly intervals until optimum clinical response has been obtainedHeart failure: The recommended starting dose of BETABEST-XL is 25 mg once daily for two weeks in patients with NYHA class II heart failure.

The renin-angiotensin-aldosterone system is one of the most important systems in pathogenesis of cardiovascular diseases including hypertenison. Therefore, it is a very successful drug target for the therapy of these diseases. Olmesartan is effective and has excellent tolerability in Diabetic and Non-diabetic Indian Patients. Moreover Olmesartan lowers the rate of coronary atheroma progression.

Indications

For the treatment of mild to moderate hypertension.

Composition

Each tablet contains:

Olmesartan

20 mg

Dosage & Administration

One tablet once daily.
Omen may be administered with or without food.
It is important to take the medication at approximately the same time each day to maintain a consistent concentration of the medication in the body.

Adverse Effects & contraindication

Contraindication : Patients who are hypersensitive to this drug or to any ingredient in the formulation.Pregnancy : Olmesartan belongs to USFDA's pregnancy category D. Hence its use should be discontinued during pregnancy.
The use of Olmesartan medoxomil in patients with severe renal impairment is not recommended

Presentation

Omen is available as a strip of 10 tablets.

Omen 40

Description

The renin-angiotensin-aldosterone system is one of the most important systems in pathogenesis of cardiovascular diseases including hypertenison. Therefore, it is a very successful drug target for the therapy of these diseases. Olmesartan is effective and has excellent tolerability in Diabetic and Non-diabetic Indian Patients. Moreover Olmesartan lowers the rate of coronary atheroma progression.

Indications

For the treatment of mild to moderate hypertension.

Composition

Each tablet contains:

Olmesartan

40 mg

Dosage & Administration

One tablet once daily.
Omen may be administered with or without food.
It is important to take the medication at approximately the same time each day to maintain a consistent concentration of the medication in the body.

Adverse Effects & contraindication

Contraindication : Patients who are hypersensitive to this drug or to any ingredient in the formulation.Pregnancy : Olmesartan belongs to USFDA's pregnancy category D. Hence its use should be discontinued during pregnancy.
The use of Olmesartan medoxomil in patients with severe renal impairment is not recommended

Presentation

Omen is available as a strip of 10 tablets.

Omen AM

Description

Combinational treatments are recommended in an individual whose blood pressure is markedly above the hypertension goal (e.g. more than 20mmHg systolic or 10mmHg diastolic). It is logical to use a combination which works by complementary mode of action. In Omen AM, Olmesartan inhibits Angiotensin II type 1 receptor which results into decrease in blood pressure and amlodipine inhibits entry of calcium in vascular smooth muscle; this causes vasodilation and reduces blood pressure. Moreover side effect like pedal edema associated with amlodipine can be minimized by co administration of olmesartan.

Olmesartan belongs to USFDA's pregnancy category D. Hence its use should be discontinued during pregnancy.
The use of Olmesartan medoxomil in patients with severe renal impairment is not recommended.

Presentation

Omen is available as a strip of 10 tablets.

Omen AM 20

Indications

• In hypertension associated with diabetes

Composition

Each Tablet consists:

Olmesartan

20 mg

Amlodipine

5 mg

Presentation

Omen AM 20 is available as a strip of 10 tablets.

Omen AM 40

Indications

• In hypertension associated with diabetes

Composition

Each Tablet consists:

Olmesartan

40 mg

Amlodipine

5 mg

Presentation

Omen AM 40 is available as a strip of 10 tablets.

Omen CT

Description

Omen CT is a combination of Olmesartan and Chlorthalidone. Chlorthalidone inhibit the reabsorption of sodium and chloride. Thus increase the excretion of water, sodium and chloride from the body leading to fall in cardiac output and blood pressure. Olmesartan is an angiotensin II receptor blocker with excellent tolerability and safety. Olmesartan inhibits the RAAS system hence decreases blood pressure by different mechanism. Thus the combination exerts the additive effect in controlling the blood pressure.

Indications

Hypertension uncontrolled with monotherapy

Composition

Each Tablet consists:

Olmesartan Medoxomil

20 mg

Chlorthalidone

12.5 mg

Dosage and Administration

One tablet daily.
Take the medication at approximately the same time each day to maintain a consistent concentration

Being a multi-factorial disease, management of hypertension often requires multiple drugs.Combining antihypertensive agents not only targets the underlying pathways for blood pressure, but also overcomes the side effect of individual drugs by complimentary mechanism of each other.Amlodipine is associated with the activation of the renin–angiotensin system (RAS) and the sympathetic nervous system. Olmesartan can effectively prevent the amlodipine associated activation of RAS.Amlodipine is known to cause peripheral edema, but when given in combination with Olmesartan, the incidence of peripheral edema is reduced. (Amlodipine is the arterio-dilator causes peripheral edema and olmesartan is veno-dilators because of which it causes post-capillary dilatation & reduces peripheral edema). Chlorthalidone can cause hypokalemia & olmesartan causes hyperkalemia thus these two drugs when given together maintain the potassium levels in blood.

Indications

Hypertension uncontrolled on dual therapy
Refractory Hypertension

Composition

Each tablet contains:

Olmesartan

20 mg

Amlodipine

5 mg

Chlorthalidone

12.5 mg

Dosage

1 tablet to be taken once daily preferably at the same time everyday.

Presentation

Omen-ACT is available as a strip of 10 tablets.

Primodil AT

Description

In patients with mild to moderate hypertension unresponsive to monotherapy with Amlodipine, additional therapy with Atenolol further improves B.P. control. Amlodipine in Primodil-AT reduces B.P. by reducing peripheral resistance. Atenolol in Primodil-AT reduces B.P. by reducing heart rate and force of myocardial contraction; this reduces cardiac output, which in turn reduces blood pressure. The combination of Amlodipine and Atenolol is also very effective in angina because in Primodil-AT, Amlodipine increases oxygen supply to myocardium, while Atenolol decreases oxygen demand.

Indications

Hypertension with IHD

Composition

Each tablet contains:

Amlodipine

5 mg

Atenolol

50 mg

Dosage

In both hypertension and angina, PRIMODIL – AT tablet is given once daily.

Side Effects

Primodil AT is well tolerated. The common side effects are headache, ankle edema, etc.

Contraindication

Hypersensitivity to either of the drugs. Congestive cardiac failure. Pregnancy and lactation.

Presentation

Primodil AT is available as a strip of 10 tablets.

Omen Trio 20

Indications

• Hypertension Uncontrolled on dual therapy
• Stage-II hypertension

Composition

Each Tablet consists:

Olmesartan

20 mg

Cilnidipine

10 mg

Chlorthalidone

12.5 mg

Presentation

Omen AM 40 is available as a strip of 10 tablets.

Omen Trio 40

Indications

• Hypertension Uncontrolled on dual therapy
• Stage-II hypertension

Composition

Each Tablet consists:

Olmesartan

40 mg

Cilnidipine

10 mg

Chlorthalidone

12.5 mg

Presentation

Omen AM 40 is available as a strip of 10 tablets.

Company Identification Number ( CIN ) : U24230MH1975PLC018296
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