He'll be replaced on Tuesday's episode by comedian Chris Gethard, the host of the truTV variety program "The Chris Gethard Show," which returns with new episodes on March 20.

The cancellation comes less than a week after Theroux and Aniston announced their decision to split following two and a half years of marriage.

"This decision was mutual and lovingly made at the end of last year," Aniston and Theroux said in a joint statement. "We are two best friends who have decided to part ways as a couple, but look forward to continuing our cherished friendship."

Jennifer Aniston and Justin Theroux announced their separation last week.

(Jordan Strauss/Jordan Strauss/Invision/AP)

Aniston and Theroux met for the final time on Valentine's Day and concluded it was time for them to go public with their split, People reported earlier this week. They had already been separated for several months at that point, according to E! News.