In pCASL, shimming the B0 field for optimal homogeneity
is indispensable for optimal labeling efficiency and
image quality. In this study the implementation of
dual-shim pCASL, with separate shim settings for imaging
and labeling, is evaluated. This approach is compared
with pCASL with identical shim settings for imaging and
labeling. Mean gray matter CBF and temporal SNR are
calculated for left-, right- and posterior flow
territories and left-right asymmetry is assessed. It is
concluded that, when 1st order shimming is applied,
application of separate shim settings during labeling
does not result in significant changes in quantitative
CBF or temporal SNR

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