man v. society= neither man have the abilities or means to achieve the dreams they have in the society in which they live.
man v. society=the inability of people to accept Lennie's disability
man v. self=Lennie's disability and size cause him to do things he doesn't understand nor can control (the desire to pet soft things and getting carried away)
man v. self=George understanding that killing Lennie himself is better than what society would do