When Dr. Doom gained control over all air-breathing life on Earth, President Jimmy Carter welcomed him in the White House and handed his office over to him. Chased by Magneto, the Beast and the Champions, Doom summoned the Hulk to fight them off, but he was ultimately defeated when he was forced to breathe his own neuro-gas.[4]

Quickly, a crowd of Thorites gathered in front of the House, and burned themselves as a sign of protestation against the take-over of their past heroes enemy. The gathering of the Corporations' leaders, and the death of Avatarr also happened there.[6]

During Herod's take-over, the White House was attacked, and Libera Cielo fell on it.[7] It was finally destroyed by the Spider-Waves.[8] As a new headquarters of the new president, an Herod creation posing as Captain America, Herod built using nanites technology the Red House,[9] but was soon destroyed in retaliation by Doom.[10]

The White House was re-purposed to suit The Red Skull's needs after he took office as the villains took over the country. He erected some statues, and adopts the Nazi flag to be used everywhere. He also installed a 'Trophy Room' where he kept memorabilia left behind from the dead heroes.[11]

The White House lawn served as the setting for the final battle between the Avengers and the United States' Sentinel Army. Sadly, the Avengers were mostly killed. President Kelly and Henry Gyrich were pleased with their progress, however, until their army was destroyed and they were killed by Hyperion, looking to take over the planet.[12]