Klonopin

Klonopin Withdrawal Side Effects

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Pharmacology

Anticonvulsant

Klonopin pharmacological profile is similar to other anxiolytic/sedative benzodiazepines. Its basic anticonvulsive properties are also similar to those of other
benzodiazepines.
Klonopin is capable of suppressing the spike and wave discharge in absence seizures (petit mal) and decreasing the frequency, amplitude, duration and spread
of discharge in minor motor seizures.

Klonopin is well absorbed orally with maximum blood concentrations occurring in 1 to 2 hours.
Klonopin is metabolized by the liver to inactive metabolites, which are excreted mainly in the urine. Less than 0.5% of a dose is excreted in the urine unchanged and from 9 to 27% of a dose may be excreted in the feces. The half-life of
the parent compound varies from approximately 18 to 50 hours.

Indications

Alone or as an adjunct in the management of myoclonic and akinetic seizures and petit mal variant (Lennox-Gastaut syndrome). May also be of some value in patients with absence spells (petit mal) who have failed to respond to succinimides.

Up to nearly 33% of the patients in some studies have shown a loss of anticonvulsant activity, often within the first 3 months of
Klonopin administration. In some cases, dosage adjustment may re-establish efficacy.

Contraindications

Warnings

Pregnancy:Recent reports indicate an association between the use of anticonvulsant drugs and an elevated incidence of birth defects in children born to epileptic women taking such medication during pregnancy. The incidence of congenital malformations in the general population is regarded to be approximately 2%; in children of treated epileptic
women this incidence may be increased 2 to 3 fold. The increase is largely due to specific defects, e.g., congenital malformations of the heart, and cleft lip and/or palate. Nevertheless, the great majority of mothers receiving anticonvulsant medications deliver normal infants.

Data are more extensive with respect to phenytoin and phenobarbital, but these drugs are also the most commonly prescribed
Klonopin. Some reports indicate a possible similar association with the use of other
Klonopin, including trimethadione and paramethadione. However, the possibility also exists that other factors,
e.g., genetic predisposition or the epileptic condition itself may contribute to or may be mainly responsible for the higher incidence of birth defects.

Klonopin should not be discontinued in patients in whom the drug is administered to prevent major seizures, because of the strong possibility of precipitating status epilepticus with attendant hypoxia and risk to both the mother and the unborn child. With regard to drugs given for minor seizures, the risk of discontinuing
medication prior to or during pregnancy should be weighed against the risk of congenital defects in the particular case and with the particular family history.

Epileptic women of childbearing age should be encouraged to seek professional counsel and should report the onset of pregnancy promptly to their physician. Where the necessity for continued use of antiepileptic medication is in doubt, appropriate consultation might be indicated.

In a reproductive study in rabbits, Klonopin administration was associated with an increased incidence of cleft palate and other anomalies at 2 dose concentrations. Accordingly,
Klonopin should be used in women of childbearing potential only when the expected benefits to the patient warrant the possible risk to a fetus.

Lactation:Mothers receiving Klonopin should not breast feed their infants.

Children:Because of the possibility that adverse effects on childhood physical or mental development could become apparent, a risk-benefit consideration of the long-term use of
Klonopin is important in pediatric patients.

Precautions

Although simultaneous administration of several Klonopin may be considered with
Klonopin, such combined therapy may result in an increase of central depressant adverse effects. In addition, the dosage of each drug may be required to be adjusted to obtain the optimum effect.

Abrupt withdrawal of Klonopin particularly in those patients on long-term, high dose therapy, may precipitate status epilepticus.
Therefore, Klonopin gradual withdrawal is essential when discontinuing
Klonopin. While Klonopin is being gradually withdrawn, the simultaneous substitution of incremental
doses of another anticonvulsant may be indicated.

A paradoxical increase in seizure activity or the appearance of new seizure types has occurred in a very few patients during
Klonopin treatment. When used in patients in whom several different types of seizures coexist,
Klonopin may increase the incidence or precipitate the onset of generalized tonic-clonic seizures (grand mal).
These phenomena may require the addition of appropriate Klonopin or an increase in their dosages. The concomitant use of valproic acid and
Klonopin may produce absence status.

They also should be warned against the concomitant use of alcohol and other CNS depressant drugs.

The CNS depressant action of benzodiazepines may be potentiated by other drugs such as alcohol, narcotics, barbiturates, nonbarbiturate hypnotics, anxiolytics, phenothiazines, thioxanthene and butyrophenone antipsychotic agents, MAO inhibitors and tricyclic antidepressants.

Benzodiazepines have produced habituation, dependence and withdrawal symptoms similar to those noted with barbiturates and alcohol. Therefore, patients who may be prone to increasing the dose of drugs on their own initiative should be under careful monitoring when receiving
Klonopin.

Klonopin and its metabolites are excreted by the kidneys; to avoid excessive accumulation, exercise caution in administering the drug to patients with impaired renal function.

Hypersecretion in the upper respiratory passages has at times been a troublesome adverse reaction during
Klonopin therapy, especially in small mentally retarded children who ordinarily have difficulty handling secretions. Treatment with
Klonopin should be instituted with caution in patients with chronic respiratory diseases.

Klonopin Adverse Effects

The most frequently occurring adverse reactions to Klonopin are referable to CNS depression. Drowsiness occurs in approximately 50% of patients and ataxia in approximately 30%. In some cases, these may diminish with time.
Behavior problems have been noted in approximately 25% of patients and increased salivation in 7%.

Others, listed by system, are:

CNS:
Alterations in behavior, which have been variously reported as aggressiveness, argumentative
behavior, hyperactivity, agitation, depression, euphoria, irritability, forgetfulness and confusion. These
behavioral reactions are particularly likely to occur in patients with a prior history of psychiatric disturbances and are known to occur
in patients with chronic seizure disorders.

Integumentary:Nonspecific erythematous, papular and maculopapular rashes, swelling of the face and eyelids, urticaria, pruritus. Hirsutism and hair loss have also been reported, but drug relationship has not been established.

Overdose

Symptoms:The cardinal manifestations of overdosage are drowsiness and confusion, reduced reflexes and coma. There are minimal effects on respiration, pulse and blood pressure, unless the overdosage is extreme. Patients have recovered from dosages of up to 60 mg without special treatment. When the effects of the drug overdosage begin to wear off,
the patient exhibits some jitteriness and over stimulation.

Treatment:Gastric lavage may be beneficial if performed soon after ingestion of Klonopin. Supportive measures should be instituted as indicated: maintenance of an adequate airway, i.v. fluids and monitoring of pulse, blood pressure and respiration. CNS stimulants and vasopressors may be used if necessary. Dialysis appears to be of no value.

Dosage

Must be determined individually according to clinical response and tolerance and depends primarily on the patient's age.

Children:In order to minimize drowsiness, the initial dose for infants and children (up to 10 years of age or 30 kg) should be between 10 and 30 mcg/kg/day and should not exceed 50 mcg/kg/day given in 2 or 3 divided doses. Dosage should be increased by no more than 250 to 500 mcg every third day until a maintenance dose of 100 to 200 mcg/kg has
been reached, unless seizures are controlled or adverse effects preclude further increase. Whenever possible, the daily dose should be divided into 3 equal doses. If doses are not equally divided, the larger dose should be given before retiring.

Adults:The initial adult dose should not exceed 1.5 mg/day divided into 3 doses. Dosage may be increased in increments of 0.5 to 1 mg every 3 days until seizures are adequately controlled or until adverse effects preclude any further increase. Maintenance dosage must be individualized for each patient depending upon response. A recommended adult
maintenance dose is 8 to 10 mg/day in 3 divided doses. Dosages in excess of 20 mg/day should be administered with caution.

The use of multiple Klonopin
may result in an increase of depressant adverse effects. This should be borne in mind whenever clonazepam is added to an already existing anticonvulsant regimen.

Klonopin
withdrawal - Sweating
Increased - A large
quantity of perspiration that is medically caused.

Klonopin
withdrawal - Palpitation
- Unusual and not normal heartbeat,
that is sometimes irregular, but rapid and forceful thumping or fluttering. It
can be brought on by shock, excitement, exertion, or medical stimulants. A
person is normally unaware of his/her heartbeat.

Klonopin withdrawal - Hypertension
- is high blood pressure, which is a
symptom of disease in the blood vessels leading away from the heart.
Hypertension is known as the “silent killer”. The symptoms are usually not
obvious, however it can lead to damage to the heart, brain, kidneys and eye, and
even to stroke and kidney failure. Treatment includes dietary and lifestyle
changes.

Klonopin withdrawal - Bradycardia-The heart rate is slowed from 72 beats per minute,
which is normal, to below 60 beats per minute in an adult.

Klonopin
withdrawal - Tachycardia
- The heart rate is speeded up to
above 100 beats per minute in an adult. Normal adult heart rate is 72 beats per
minute.

Klonopin
withdrawal - ECG Abnormal
- A test
called an electrocardiogram (ECG) that records the activity of the heart. It
measures heartbeats as will as the position and size of the heart’s four
chambers. It also measures if there is damage to the heart and the effects of
drugs or mechanical devices like a pacemaker on the heart. When the test is
abnormal this means that one or more of the following are present: heart
disease, defects, beating too fast or too slow, disease of the blood vessels
leading from the heart or of the heart valves, and/or a past or about to occur
heart attack.

Klonopin
withdrawal - Flushing
- The skin all over the body turns red.

Klonopin withdrawal - Varicose Vein -Unusually swollen veins
near the surface of the skin that sometimes appear twisted and knotted, but
always enlarged. They are called hemorrhoids when they appear around the
rectum. The cause is attributed to hereditary weakness in the veins aggravated
by obesity, pregnancy, pressure from standing, aging, etc. Severe cases may
develop swelling in the legs, ankles and feet, eczema and/or ulcers in the
affected areas.

Klonopin
withdrawal -
Gastrointestinal
(Involving
the stomach and the intestines)

Klonopin withdrawal - Abdominal Cramp/Pain - Sudden, severe, uncontrollable and painful shortening and
thickening of the muscles in the belly. The belly includes the stomach as well
as the intestines, liver, kidneys, pancreas, spleen, gall bladder, and urinary
bladder.

Klonopin withdrawal - Belching
- Noisy release of gas from the stomach through the mouth; a burp.

Klonopin withdrawal - Constipation- Difficulty in having a bowel movement where the material in the bowels is
hard due to a lack of exercise, fluid intake, and roughage in the diet, or due
to certain drugs.

Klonopin withdrawal - Diarrhea - Unusually frequent and excessive, runny bowel movements that may
result in severe dehydration and shock.

Klonopin
withdrawal - Dyspepsia - Indigestion. This is the discomfort you experience after eating. It
can be heartburn, gas, nausea, a bellyache or bloating.

Klonopin withdrawal - Flatulence
- More gas than normal in the digestive organs.

Klonopin withdrawal - Anaphylaxis
- A violent, sudden, and severe drop
in blood pressure caused by a re-exposure to a foreign protein or a second
dosage of a drug that may be fatal unless emergency treatment is given right
away.

Klonopin withdrawal - Asthenia-A physically
weak condition.

Klonopin
withdrawal - Chest Pains
-
Severe discomfort in the chest caused by not enough oxygen going to the heart
because of narrowing of the blood vessels or spasms.

Klonopin withdrawal - Edema of
Extremities-Abnormal
swelling of the body’s tissue caused by the collection of fluid.

Klonopin withdrawal - Fall
- To suddenly lose your normal
standing upright position as if you were shot.

Klonopin
withdrawal - Fatigue
- Loss of normal strength so as to
not be able to do the usual physical and mental activities.

Klonopin
withdrawal - Fever
- Abnormally high body temperature,
the normal being 98 degrees Fahrenheit or 37 degrees Centigrade in humans, which
is a symptom of disease or disorder in the body. The body is affected by
feeling hot, chilled, sweaty, weak and exhausted. If the fever goes too high,
death can result.

Klonopin
withdrawal - Influenza-like
Symptoms -
Demonstrating irritation of the respiratory tract (organs of breathing) such as
a cold, sudden fever, aches and pains, as well as feeling weak and seeking bed
rest, which is similar to having the flu.

Klonopin
withdrawal - Leg Pain
- A
hurtful sensation in the legs that is caused by excessive stimulation of the
nerve endings in the legs and results in extreme discomfort.

Klonopin withdrawal - Malaise-The somewhat
unclear feeling of discomfort you get when you start to feel sick.

Klonopin
withdrawal - Syncope-A short
period of light headedness or unconsciousness (black-out) also know as fainting
caused by lack of oxygen to the brain because of an interruption in blood
flowing to the brain.

Klonopin withdrawal - Tightness of
Chest - Mild or sharp discomfort, tightness
or pressure in the chest area (anywhere between the throat and belly). The
causes can be mild or seriously life-threatening because they include the heart,
lungs and surrounding muscles.

Klonopin
withdrawal - Hemic and Lymphatic Disorders(Involving
the blood and the clear fluids in the tissues that contain white blood cells)

Klonopin withdrawal - Bruise
- Damage to the skin resulting in a
purple-green-yellow skin coloration that’s caused by breaking the blood vessels
in the area without breaking the surface of the skin.

Klonopin
withdrawal - Anemia- A condition
where the blood is no longer carrying enough oxygen, so the person looks pale
and easily gets dizzy, weak and tired. More severely, a person can end up with
an abnormal heart, as well as breathing and digestive difficulties. The causes
of anemia are not enough protein in the red blood cells, or missing and
chemically destroyed red blood cells, as well as diseased or destroyed bone
marrow.

Klonopin withdrawal - Nosebleed
- Blood lost from the part of the
face that has the organs of smell and is where the body takes in oxygen.

Klonopin
withdrawal - Hematoma
- Broken blood vessels that cause a
swelling in an area on the body.

Klonopin
withdrawal - Lymphadenopathy
Cervical-The lymph
nodes in the neck, which are part of the body’s immune system get swollen and
enlarge by reacting to the presence of a drug. The swelling is the result of
the white blood cells multiplying in order to fight the invasion of the drug.

Klonopin
withdrawal - Arthralgia-Sudden sharp
nerve pain in one or more joints.

Klonopin
withdrawal - Arthritis-Painfully inflamed and swollen joints. The reddened
and swollen condition is brought on by a serious injury or shock to the body
either from physical or emotional causes.

Klonopin
withdrawal - Back Discomfort
- Severe physical distress in the area from the neck to the pelvis along the
backbone.

Klonopin withdrawal - Bilirubin Increased- Bilirubin is a waste product of the breakdown
of old blood cells. Bilirubin is sent to the liver to be made water-soluble so
it can be eliminated from the body through emptying the bladder. A drug can
interfere with or damage this normal liver function creating liver disease.

Klonopin
withdrawal - Gout
- A severe arthritis condition that is caused by the dumping of a waste product
called uric acid in the tissues and joints. It can become worse and cause the
body to develop a deformity after going through stages of pain, inflammation,
severe tenderness, and stiffness.

Klonopin
withdrawal - Hyperglycemia
- An unhealthy amount of sugar in the blood.

Klonopin withdrawal - Increased Weight - A concentration and storage of fat in the body
accumulating over a period of time caused by unhealthy eating patterns, that can
predispose the body to many disorders and diseases.

Klonopin
withdrawal - Jaw Pain - The pain due to irritation and swelling of the nerves associated with
the mouth area where it opens and closes just in front of the ear. Some of the
symptoms are pain when chewing, head aches, losing your balance, stuffy ears or
ringing in the ears, and teeth grinding.

Klonopin withdrawal - Jaw Stiffness
- The result of squeezing and grinding the teeth while asleep that can cause
your teeth to deteriorate as well as the muscles and joints of the jaw.

Klonopin
withdrawal - Joint Stiffness- A loss of free motion and easy flexibility where any
two bones come together.

Klonopin withdrawal - Muscle Cramp - When muscles contract uncontrollably without warning and do not
relax. The muscles of any of the body’s organs can cramp.

Klonopin withdrawal - Restless Legs
- A need to move the legs without any apparent reason. Sometimes there is pain,
twitching, jerking, cramping, burning, or a creepy-crawly sensation associated
with the movements. It worsens when a person is inactive and can interrupt
one’s sleep so one feels the need to move to gain some relief.

Klonopin
withdrawal - Shaking
- Uncontrolled quivering and trembling as if one is cold and chilled.

Klonopin
withdrawal - Sluggishness
- Lack of alertness and energy, as well as being slow to respond or perform in
life.

Klonopin withdrawal - Tics - A contraction of a muscle causing a repeated movement not
under the control of the person usually on the face or limbs.

Klonopin
withdrawal - Tremor
- A nervous and involuntary vibrating or quivering of the body.

Klonopin withdrawal - Amnesia - Long term or short term, partial or full memory loss created by
emotional or physical shock, severe illness, or a blow to the head where the
person was caused pain and became unconsciousness.

Klonopin withdrawal - Carbohydrate
Craving - A drive
and craving to eat foods rich in sugar and starches (sweets, snacks and junk
foods) that intensifies as the diet becomes more and more unbalanced due to the
unbalancing of the proper nutritional requirements of the body.

Klonopin
withdrawal - Confusion
- Not able to think clearly and understand in order to make a logical decision.

Klonopin
withdrawal - Crying Abnormal
- Unusual and not normal fits of weeping for short or long periods of time for
no apparent reason.

Klonopin withdrawal - Depersonalization
- A condition where one has lost a normal sense of personal identity.

Klonopin
withdrawal - Depression
- A hopeless feeling of failure, loss and sadness that can deteriorate into
thoughts of death.

Klonopin
withdrawal - Disorientation
- A loss of sense of direction, place, time or surroundings as well as mental
confusion on personal identity.

Klonopin
withdrawal - Dreaming Abnormal
- Dreaming that leaves a very clear, detailed picture and impression when awake
that can last for a long period of time and sometimes be unpleasant.

Klonopin
withdrawal - Emotional
Lability- Suddenly breaking out
in laughter or crying or doing both without being able to control the outburst
of emotion. These episodes are unstable as they are caused by things that
normally would not have this effect on an individual.

Klonopin withdrawal - Feeling Unreal - The awareness that one has an undesirable emotion like
fear but can’t seem to shake off the irrational feeling. For example, feeling
like one is going crazy but rationally knowing that it is not true. The quality
of this side effect resembles being in a bad dream and not being able to wake
up.

Klonopin
withdrawal - Forgetfulness
- Unable to remember what one ordinarily would remember.

Klonopin
withdrawal - Insomnia
- Sleeplessness caused by physical stress, mental stress or stimulants such as
coffee or medications; it is a condition of being abnormally awake when one
would ordinarily be able to fall and remain asleep.

Klonopin
withdrawal - Reproductive Disorder Female

Klonopin
withdrawal - Breast Neoplasm
- A tumor or cancer, of either of the two milk-secreting
organs on the chest of a woman.

Klonopin
withdrawal - Menorrhagia- Abnormally heavy menstrual period or a
menstrual flow that has continued for an unusually long period of time.

Klonopin
withdrawal - Menstrual Cramps
- Painful, involuntary uterus contractions that women experience around the time
of their menstrual period, sometimes causing pain in the lower back and thighs.

Klonopin
withdrawal - Menstrual
Disorder - A disturbance or derangement in the normal function of a woman’s
menstrual period.

Klonopin
withdrawal - Pelvic
Inflammation - The reaction of the body to infectious, allergic, or chemical
irritation, which in turn causes tissue irritation, injury, or bacterial
infection characterized by pain, redness, swelling, and sometimes loss of
function. The reaction usually begins in the uterus and spreads to thefallopian tubes, ovaries, and other areas
in the hipbone region of the body.

Klonopin
withdrawal - Premenstrual
Syndrome - Various physical and mental symptoms commonly experienced by women of
childbearing age usually 2 to 7 days before the start of their monthly period.
There are over 150 symptoms including eating binges, behavioral changes,
moodiness, irritability, fatigue, fluid retention, breast tenderness, headaches,
bloating, anxiety, and depression. The symptoms cease shortly after the period
begins, and disappear with menopause.

Klonopin
withdrawal - Asthma - A disease of the breathing system initiated by and allergic reaction
or a chemical with repeated attacks of coughing, sticky mucus, wheezing,
shortness of breath, and a tight feeling in the chest. The disease can reach a
state where it stops a person from exhaling, leading to unconsciousness and
death.

Klonopin
withdrawal - Breath Shortness
-
Unnatural breathing using a lot off effort resulting in not enough air taken in
by the body.

Klonopin
withdrawal - Bronchitis
- Inflammation of the two main
breathing tubes leading from the windpipe to the lungs. The disease is marked
with coughing, a low-grade fever, chest pains, and hoarseness, caused by an
allergic reaction.

Klonopin
withdrawal - Coughing
- A cough is the response to an
irritation, such as mucus, that causes the muscles controlling the breathing
process to expel air from the lungs suddenly and noisily to keep the air
passages free from the irritating material.

Klonopin
withdrawal - Laryngitis
- Inflammation of the voice box
characterized by hoarseness, sore throat, and coughing. It can be cause by
straining the voice or exposure to infectious, allergic or chemical irritation.

Klonopin
withdrawal - Nasal Congestion
- The
presence of an abnormal amount of fluid in the nose.

Klonopin
withdrawal - Pneumonia
Tracheitis - Bacterial infection of the air passageways and lungs that causes
redness, swelling and pain in the windpipe. Other symptoms are high fever,
chills, pain in the chest, difficulty in breathing, and coughing with mucus
discharge.

Klonopin
withdrawal - Sinus Congestion
- The
mucus-lined areas of the bones in the face that are thought to help warm and
moisten air to the nose. These areas become clogged with excess fluid or
infected.

Klonopin
withdrawal - Sinus Headache
- The
abnormal amount of fluid in the hollows of the face bone area especially around
the nose. This excess fluid creates pressure, causing pain in the head.

Klonopin
withdrawal - Sinusitis
- The body reacting to chemical
irritation causing redness, swelling and pain in the area of the hollows in the
facial bones especially around the nose.

Klonopin
withdrawal - SKELETAL

Klonopin withdrawal - Neck/Shoulder Pain
- Hurtful sensations
of the nerve endings caused by damage to the tissues in the neck and shoulder
signaling danger of disease.

Klonopin
withdrawal - Acne
- Eruptions of the oils glands of the
skin, especially on the face, marked by pimples, blackheads, whiteheads, bumps,
and more severely, by cysts and scarring.

Klonopin withdrawal - Alopecia - The loss of hair or baldness.

Klonopin
withdrawal - Eczema
- A severe or continuing skin disease
marked by redness, crusting and scaling with watery blisters and itching. It is
often difficult to treat and will sometimes go away only to reappear again.

Klonopin
withdrawal - Dermatitis
- Generally irritated skin that can
be caused by any of a number of irritating things such as parasites, fungus,
bacteria, or foreign substancescausing an allergic reaction. It is a general inflammation of the skin.

Klonopin
withdrawal - Dry Lips
- The
lack of normal moisture in the fleshy folds that surround the mouth.

Klonopin withdrawal - Dry Skin -The lack of normal moisture/oils in the
surface layer of the body. The skin is the body’s largest organ.

Klonopin withdrawal - Rash - A skin eruption or discoloration that may or may not be
itching, tingling, burning, or painful. It may be caused by an allergy, an skin
irritation, a skin disease.

Klonopin withdrawal - Skin Nodule - A bulge, knob, swelling or outgrowth in the skin
that is a mass of tissue or cells.

Klonopin withdrawal - SPECIAL SENSES

Klonopin withdrawal - Conjunctivitis
- Infection of the membrane that covers the eyeball and lines the eyelid, caused
by a virus, allergic reaction, or an irritating chemical. It is characterized
by redness, a discharge of fluid and itching.

Klonopin withdrawal - Dry Eyes - Not enough moisture in the eyes.

Klonopin withdrawal - Earache - Pain in the ear.

Klonopin withdrawal - Eye Infection
- The invasion of the eye tissue by a bacteria, virus, fungus, etc, causing
damage to the tissue, with toxicity. Infection spreading in the body progresses
into disease.

Klonopin withdrawal - Eye Irritation
- An inflammation of the eye.

Klonopin withdrawal - Metallic Taste
- A range of taste impairment from distorted taste to a complete loss of taste.

Klonopin withdrawal - Pupils Dilated
- Abnormal expansion of the blace circular opening in the center of the eye.

Klonopin withdrawal - Visual Disturbance
- Eyesight is interfered with or interrupted. Some disturbances are light
sensitivity and the inability to easily distinguish colors.

Klonopin
withdrawal - URINARY
SYSTEM DISORDER

Klonopin
withdrawal - Blood in Urine-
Blood is present when one empties liquid waste product of the kidneys through
the bladder by urinating in the toilet turning the water pink to bright red. Or
you could see pots of blood in the water after urinating.

Klonopin
withdrawal - Dysuria
- Difficult or painful urination.

Klonopin
withdrawal - Urinary Frequency - Having to urinate more often than usual or between unusually short
time periods.

Klonopin
withdrawal - Urinary Tract
Infection - An invasion of bacteria, viruses, fungi, etc., of the
system in the body that starts with the kidneys and eliminates urine from the
body. If the invasion goes unchecked it can injure tissue and progress into
disease.

Klonopin withdrawal - Angioedema
- Intensely itching and swelling welts on the skin called hives caused by an
allergic reaction to internal or external agents. The reaction is common to a
food or a drug. Chronic cases can last for a long period of time.

Klonopin
withdrawal - Toxic Epidermal
Necrolysis - An abnormal condition where a large portion of skin
becomes intensely red and peels off like a second-degree burn. Often the
symptoms include blistering.

Klonopin withdrawal - Pancreatitis - Chemical irritation with redness, swelling, and
pain in the pancreas where digestive enzymes and hormones are secreted.

Klonopin withdrawal - QT Prolongation
- A very fast heart rhythm disturbance that is too fast for the heart to beat
effectively so the blood to the brain falls causing a sudden loss of
consciousness and may cause sudden cardiac death.

Klonopin withdrawal - Rhabdomyolysis
- The breakdown of muscle fibers that releases the fibers into the circulatory
system. Some of the fibers are poisonous to the kidney and frequently result in
kidney damage.

Klonopin withdrawal - Serotonin Syndrome
- A disorder brought on by excessive levels of serotonin caused by drugs and can
be fatal as death from this side effect can come very rapidly.

Klonopin withdrawal - Thrombocytopenia
- An abnormal decrease in the number of blood platelets in the circulatory
system. A decrease in platelets would cause a decrease in the ability of the
blood to clot when necessary.

Klonopin withdrawal -
Torsades de Pointes - Unusual rapid
heart rhythm starting in the lower heart chambers. If the short bursts of rapid
heart rhythm continue for a prolonged period it can degenerate into a more rapid
rhythm and can be fatal.