Restrict port IP addresses

Im getting ready to configure a CISCO ASA 5510 for our network. Im fairly new to configuring firewalls and new to CISCO in general. We host our own exchange server and we have our incoming email filtered for spam and viruses by an outside company. Would it be possible to restrict forwarding on port 25 to only those IP addresses used by our email filtering services?

Currently our exchange server is rejecting about 300k emails per day from computers trying to relay emails using only our IP address as the target. Id like to see as many of those as possible rejected before they ever reach our server.