The residuals for the H-NLM were considerably larger (Fig 2B,C). The HK-LM did better than the H-NLM using the GH map by about a factor of 5 (superior CVRMSE 0.25 vs 1.22; inferior 0.28 vs 1.55; Fig 2B) and the H map by about a factor of 2 to 3 (superior CVRMSE 0.22 vs 0.67; inferior 0.24 vs 0.56; Fig 2C).

Fig. 2: (A) The HK-LM (blue) and H-NLM (orange △) models plotted against the control (green ○), glaucoma (black ●), and ION (red ■) subjects using the GH map. (B) The residuals as in (A). (C) The residuals using the H map.

Fig. 2: (A) The HK-LM (blue) and H-NLM (orange △) models plotted against the control (green ○), glaucoma (black ●), and ION (red ■) subjects using the GH map. (B) The residuals as in (A). (C) The residuals using the H map.