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I will go about this by answering two questions. First, what is Popper's general approach when attempting to distinguish science from pseudo-science? Second, what specifically did he dislike about Freudian psychoanalysis? (Historically, Popper actually developed his general theory in response to his particular dislike of contemporary marxism and Adlerian and Freudian Psychoanalysis.)

Falsificationism

Popper proposes that in the empirical domain, nothing can ever be proved true. No swans are white because you've never seen a black swan, and you've seen thousands of swans? Well, maybe the next swan you'll see is black. This may be unlikely, but not impossible, and thus, there is no proof. (The general problem is the problem of induction, as discussed by Hume, which leads into an infinite regress.)

Thus, science is not what is proved true. Science is also not what can explain a lot of observed phenomena, because telling stories about the past is easy and always open. Instead, Popper proposes science is that which contains the means of its own refutation. Everything may be wrong, and a quality of the good ways of exploring the world is that they make clear how to see if they could be wrong. Thus, good science

makes bold conjectures about how the world is like, that is, claims the world is in a state which would be surprising unless the theory were true

derives from this predictions of what should never be the outcome of experiments

would appears as false - falsified - if those outcomes were in fact to turn up

Thus, something that is never false is unscientific, and if it claims to be science, it is pseudo-science. That which could easily be shown false, but has so far withstood many genuine attempts at falsifying it can be scientific.

A few notes: Popper did not claim that anything that is not falsifiable is bad, or false. Something may be true and unfalsifiable, and it may be good and unfalsifiable. But to claim the status of being scientific, it needs to be falsifiable.

Psychoanalysis

Popper used to be a fan of psychoanalysis, especially of the Adlerian brand influential in Vienna in that time. His friends, he observed, were especially impressed by the ability of Adlerians to explain any and all phenomena. A man is honest? It's this kind of early-childhood event that caused this. A man is dishonest? It's that kind of early-childhood event. The Adlerians were never wrong. And it was not clear how they could ever be wrong, as they could post-hoc tell a story about how any given phenomenon fit their theories perfectly. Everything in the world was to them evidence for their theory.

This eventually came to appear to Popper as deeply misguided. Adler himself, with whom Popper worked, was exclusively telling stories about how the past proved or confirmed his theory, never claiming how a possible future state of events could disprove it. He had no predictions, and thus, no truly scientific experiments.

This made Popper not only give up on psychoanalysis, but led him to use it as one primary example of what he considered pseudo-science.

The same story also applies to Freudian psychoanalysis; between all the different complexes and drives, every possible human action or mindset could be explained as originating from childhood experiences and conflicting unconscious mental agents. But Freudians did not make bold conjectures, and did not attempt to falsify their theory with truly scientific experiments.

$\begingroup$However, this does seem like you being a bit petty over me asking for sources on your controversial claims regarding gender.$\endgroup$
– jonaJan 14 '16 at 19:36

$\begingroup$As I stated in the other comments section it is hardly controversial when backed by extensive scientific research. I just looked at your profile after you left your comment, I actually thought this was a good answer. But it did need a reference, which is the only reason I mentioned it. Please try to not jump to conclusions, I was only trying to help improve your well written answer so that others might see where your comments came from. We are all volunteers here.$\endgroup$
– ComteJan 18 '16 at 12:20

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$\begingroup$Don't worry about it, it may actually be good for others to see that people can work out there misunderstandings so quickly.$\endgroup$
– ComteJan 18 '16 at 12:26