Copyright Statement

Abstract

Amoebic infections in fish are most likely underestimated and sometimes overlooked due to the challenges
associated with their diagnosis. Amoebic diseases reported in fish affect either gills or internal
organs or may be systemic. Host response ranges from hyperplastic response in gill infections to inflammation
(including granuloma formation) in internal organs. This review focuses on the immune response
of Atlantic salmon to Neoparamoeba perurans, the causative agent of Amoebic Gill Disease (AGD).