I've read that playing those characters could have contributed to their demise - as we all know stress and intense emotion can shorten lifespans. Sometimes it does seem like the B5 cast are paying the price of those characters flaws (many of which seem to eho the problems of the people playing them)

It was and still is a great show but theres no curse to speak of. From what I've read about each passing there is a story relating to either mental or phyiscal health thats caused by the consumption of something. People don't stop to think this 'something' actually can contribute greatly to a quick end, and in our society nothing seems to be done in moderation anymore.. its all overkill.

Everyone has their problems in life - It's just that the B5 cast had problems that ended up killing them sooner than most. A damn shame. Chain smoking, alcohol and drug addiction, over-eating etc... These are all issues that affect at least one person in every family to be honest. My uncle for example died of liver cancer caused by the drugs he took often earlier in life.