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Sunday, 26 May 2013

Definition:
It occur due to severe cause of hepatic encephalopathy.Types of Hepatic Failure:

Fulminant hepatic failure.

Subfulminant hepatic failure.

1. Fulminant hepatic failure:

Defined as severe hepatic failure with development of hepatic encephalopathy within 8 weeks after the onset of acute liver disease.

Causes:

In the absence of evidence of pre-existing in chronic liver disease that also lead to hepatic encephalopathy.

2. Subfulminant hepatic failure:
It is term used when encephalopathy occur between 8 weeks and 6 months after the onset of acute liver disease and carries an equally poor prognosis.Causes:
About 70% cases are caused by acute viral hepatitis.
50% due to hepatitis B.
Other causes are hepatitis A. E & D.

Clinical Features:
Jaundice.
Hepatic encephalopathy.
Small live on examination.

The Hospital acquired pneumonia (HAP) or nosocomial pneumonia is said to be any pneumonia that can occur to the patient in a hospital at least 48–72 hours after admission.
It is usually caused by a bacterial infection, instead of a viral infection.
HAP is the second most common nosocomial infection (urinary tract infection is the most common) and accounts for 15–20% of the total.
HAP typically lengthens a hospital stay by 1–2 weeks.

Saturday, 25 May 2013

Definition:
Measurement of PaCO2 and PaO2 and H+ Conc. in arterial blood is valuable in assessment of hypoxemia or acid-base balance in respiratory failure and asthama.

Procedure:
Heparinize syringe with 0.1 ml heparin to prevent clot formation.
Draw blood from radial or brachial or femoral artery.
The sample should be immersed in ice bag immediately to prevent metabolism that can reduce PaO2 and increase PaCO2.

Definition:
When Patient fails to improvement in breathing by other measures, they should need oxygen therapy by Some respiratory support with mechanical ventilation, that improves the elimination of CO2.

Types of Mechanical Ventilation:
There are two types of mechanical ventilation;

Non- Invasive mechanical ventilation.

Invasive mechanical ventilation.

1- Non- Invasive mechanical ventilation:
In NIMV respiration is supported with face mask or nasal cannula and Endotracheal intubation avoided.
In this, Patient should be conscious, cooperative and be able to breath spontaneously and cough effectively by him or her self.
This Technique is commonly performed in COPD and Pneumonia.2- Invasive mechanical ventilation:
In IMV Endotracheal tube is passed.
Patient may require;
* Full support and Partial support ventilator.Full support Ventilator:
In this, all respiration controlled by ventilator.
In this case, Ventilator does not allow the spontaneous breathing.
Patient deeply sedative with short acting IV general anesthesia and paralyzed with muscles relaxant.Partial support ventilator:
In this, all respiration does not controlled by ventilator, while patient also have his/her own effort.
It does not require deeply sedation or paralyses with muscles relaxant.

Indications:
Respiratory failure (Type II) that does not response to the medical treatment.
Head Injury- Patient have altered in mental status, and it controlled hyperventilation that reduce the Intra-cranial pressure.
Chest Injury- Flail chest, Pneumothorax and Hemothorax etc that reduces the breathing.
Severe Pulmonary edema.

Complications:
Tube insertion in one lung cause collapse of other lung.
Ventilator can induce the lung injury that leads to lungs infection.
It can cause Nosocomial, Hospital Acquired Pneumonia )HAP).
Abdominal Distention.
Fall in cardiac output (CO) due to positive pressure in lungs and thorax that reduce the venous return.

Friday, 3 May 2013

Monitoring:
The cardiac monitoring commonly known as continue monitoring of the heart activity. Generally it shows, Electrocardiography (Relatively cardiac rhythm, Heart rate etc), It can also measure the hemodynamically status of patient via pressure of blood flow within the circulatory system, and can record also the patient's temperature, respiration and pulse oximetery.Electrocardiography:
Heart rate
Rhythm
Diagnostic values

Hemodynamically status:
Blood Pressure;

Systolic BP
Diastolic
Mean BP

Temperature:

Normal value is;

98.6 F

37 C

* It is usually measured by anal canal.

Respiration:

It is normally 12 to 20 breathes in Adult.

20 to 25 in Childrens.

25 to 40 in Infants.

Pulse Oximetery:

It is use to measure the oxygen saturation and the pulse rate in the peripheral circulation.

Work:
By a low intensity light beamed, from a light emitting diode (LED) to a light receiving photo-diode.
Two thin beam of light, one of them is; Red and other is; Infrared are transmitted through blood and body tissues, and Some of portion of light is absorbed by blood and body tissue, a photo-diode measure the proportion of the light that passes through the blood and body tissues, that show the pulse oximetery on monitor.
The relatively light absorbed by oxygenated blood is differ from the deoxgenated blood.

Unreliable:
If patient have poor peripheral perfusion, by vasoconstiction, hypotension, BP cuff inflated by the sensor, hypothermia, other causes of poor blood flow the pulse oximetery not show the accurate results.

Introduction:
To familiarize to the physician with the importance of Short and long caliber peripheral lines are preferred for rapid volume resuscitation.Access to Circulation:
Its use in the management of traumatized patient.
Venous access can use for investigation, blood sampling, fluid resuscitation and medication via injection.
There are Following Places in body that use for the Venous Access;

Percutaneous peripheral venous access.

Central access.

Surgical cut-down.

Intra-osseous access.

Percutaneous peripheral venous access:
Most Suitable site for PVA is Forearm, Cubital fossal vein.
Mainly there are used two large bore IV catheters (14 and 16 gauge).
Sterilize technique should be use in emergency and urgency situation.
Lower limbs can also be used for the venous access but complication can occur like thrombosis, cellulitis and phlebitis.

Central access:
It is use in traumatized unstable patient or in shocked patient.
There is use of CV line, in size of (8 to 12 French).
They provide high flow rate because of large diameter (2.5 to 4 mm) of catheter (Swan Sheath).
It can also use for the monitoring, assessing, to check volume status and for resuscitation.

* There are some sites where you can perform the central venous access;

Advantages:
Easily accessible
It maintain CV line in fixed position due to fibrous tissue (Attached to the 1st Rib, clavicle and subclavicle muscles).
Allows the measurement of CVP (Central venous pressure).

2. Internal Jugular vein:Criteria : IJV is most popular in CV line insertions.
But this site is not preferred in neck trauma (C-spine).

Advantages:
Right IJV have extra advantages rather than left IJV;
It Provide the straight route to the right heart.
It is Slightly larger than left IJV.
The dome of pleura is lower on the right side.

Disadvantages:
On left side it can cause thoracic duct injury which not occur on right side.

3. Femoral vein:Criteria : Its is easy to cannulation because it is large in diameter of vein.

Advantages:
Ease of insertion.
No risk of thoracic injury.

Disadvantages:
Limits the flexion of leg at the hip.
Thrombosis.
Femoral artery puncture.

Surgical cut-down:
The procedure in which a vein is exposed through an incision and cannulated under the direct vision.
It is particularly performed in those patient in whom Percutaneous and central access are contraindicated that are traumatized patient and this procedure normally performed in children.

Sites for venous Cut-down:
It is mostly performed in superficial veins;

Long/Greater saphenous vein at the ankle.

Proximal long/Greater saphenous veins.

Antecubital veins.

1. Long/Greater saphenous vein at the ankle:

It is Approx. 1 cm above and anterior to the center of the medial malleolus.
This is safe site and have low morbidity.
It is of smaller in size at the ankle difficult to perform the procedure.
It is away from the central circulation.
It is not beneficial in leg fractures and splinting etc.

2. Proximal long/Greater saphenous veins:
It is Approx. 5 cm inferior to the inguinal ligament and 5 cm medial to the femoral pulse (or 5 cm medial to the mid point of the inguinal ligament in a pulse less patient).
It is better alternative to the ankle venous cut-down, it is near to the central circulation.

3. Antecubital veins:
Basilic vein, Proximal and distal cephalic veins in the arm can be used for a cut-down.
Basilic vein, because of its less acute union with the Subclavian vein is preferred site.
In complication damage to the brachial artery and median nerve.

Intra-osseous access:
The ability of the bone marrow to accept an infusion of fluids and drugs with subsequent effects like those of an intravenous infusion has been well documented.Criteria: This route should be utilized for initial resuscitation.Sites: Any marrow containing cavity is a potential site for infusion, These are the commonly recommended sites;

Proximal Tibia.

Distal Tibia.

Distal Femur.

1. Proximal Tibia:

Anteromedial surface, 2-3 cm below the tibial tuberosity.

2. Distal Tibia:

Anterior surface of the distal tibia, approximately 2 cm above the medial malleolus.

3. Distal Femur:

Antero-lateral surface, 3 cm above the lateral condyle of femur.

Advantages:
This route can be quickly, safely and reliably established and permits rapid venous uptake of the drugs and fluids.

Complications:
It can cause infections like local cellulitis and abscess.
Osteomyelitis.
Fracture of the bone.
Compartment syndrome.
Epiphyseal plate injury.

Management:
Treat the cause of Bradycardia.
TPM in Symptomatic bradycardia, if there is reversible causes.
PPM in Symptomatic bradycardia, if there is irreversible causes.
Acute Symptomatic bradycardia can respond to the (Atropine 0.6 mg).

(Tachycardia):Definition:
The heart rate more than 100 beats per minute or more, is known as Tachycardia.

Definition:
It is the monitoring of the conc. or PaCO2 in the respiratory gases, its a main tool to measure CO2 during Anesthesia ans Intensive care.
It is recorded in form of graph that plot; expiration against time.

Main Uses:
The Capnogram directly use for the monitoring of inhaled and exhaled Conc. or partial pressure of CO2.
The Capnogram indirectly use for the monitoring of the CO2 Partial pressure of Arterial blood.

* In a healthy individual there is very small difference between arterial blood and exhaled gas CO2 partial pressure.
* In presence of lung disease and congenital heart diseases, there is more than 1 kPa is difference between arterial blood and exhaled gas CO2 partial pressure

Diagnostic Uses:
It provides the information about Carbon-dioxide production i.e;

Pulmonary perfusion.

Alveolar ventilation.

Respiratory pattern.

Elimination of CO2 from anesthesia breathing circut and ventilators.

The graph can be effected by some lung disease, i.e;

Bronchitis,

Emphysema,

Asthma.

The graph cannot be affected by pulmonary embolism and some heart disease, i.e;

There is no change in graph relation, but actual they effects the relation between exhaled carbon-dioxide partial pressure and arterial blood.

Wednesday, 1 May 2013

Definition:
Central venous line is large bore cannula that use to administer the large volume of fluid and medication.Indications:
In open heart surgery.
Fluid replacement in Shock.
Total Parenteral Nutrition (TPN).
Administration of irritant medication.
Hemodialysis.
Aspiration of Air embolism.
Venous assessing during CPR.

2. Colloids:
Those solutions that contains large insoluble molecules, e.g; Gelatin and blood are colloids.

Importance:
Also known as true solutions.
Capable to passing through semi Permeable membrane.
They are physically opposite to Colloids.
Preserve high colloid osmotic pressure in blood.
These are costly solutions.

Definition:
It is a medical procedure that performed by a tube that enter from nose to throat to esophagus to end stomach.

Uses of Nasogastric Tube:
Its use for the feeding.
Administration of medication.
For other agents like; activated Charcoal.
Nasogastric aspiration (gastric lavage).
To empty the stomach from poisoning substances or other secretions, bag attached and maintain below the patients position gravity helps to empty the stomach.
To prevent the aspiration of stomach contents.

How to Inserted?
Before the insertion take the size from patient, from the tip of the nose to ear loop, then down toward the xiphoid sternum to roughly below 5 cm.
Use the local anesthesia ( 2% Xylocaine gel) before insertion, at the end tip of tube.
Enter the tube in this pathway; Nose __Throat__Esophagus__Stomach.
Size Varies: 12-14 Gauge in Green Color, 16-18 Gauge in Red Color.
There are four marking on NG tube;
1st at 18" (46 cm)
2nd at 22" (56 cm)
3rd at 26" (66 cm)
4th at 30" (76 cm)
When you enter the tube from mouth to stomach patient may awake or show gag reflexes.
Say patient to mimic like swallowing, give him/her water to sip with straw.
And during this procedure enter the tube in stomach.

Caution:
NG tube must be inserted by an experienced person.
Avoid to enter the NG tube into the trachea.

Confirmation:

It can confirm by Air syringe to enter air in stomach it will be distended.

Aspirate the stomach content check its pH by litmus paper; it should be 5.5 or below acidic.

You can perform an x-ray.

Contraindications:
Its is contraindicated in Skull fractures (Basal), Severe facial fracture, Obstruction on esophagus and nose too and in gastric bypass surgery.

Complications:

Its can cause nose bleeding.

Sinusitis.

Its lead to sore throat and swelling in nose.

Perforation of esophagus.

Aspiration of Lungs.

Lungs Collapsed.

If not propered sized it can go in duodenum (confirmed by gastric enzymes).

For intubation patient should be unconscious or give general anesthesia to the conscious patient.

Procedure:

Make the position, open the patient's mouth with hand and jaw with index finger.

Hold laryngoscope in your left hand or non-dominant hand, enter it in patient's mouth.

Take direct it to in line to see epiglottis, glottis and vocal cord for intubation in trachea.

Often an assistant is use to press the trachea to direct view of larynx.

Anesthetic take ETT to enter in trachea with eyes view in optic light with his/her right or dominant hand.

Tube enter from the side of balloon till the end of trachea above 2 cm of Carina.

Inflate the balloon by cuff with syringe full of air.

Confirmation:

Anesthetic Confirmed by stethoscope to listen the breaths sound.

It can also confirmed by chest x-ray (CXR).

Complications:
ETT intubation can cause edema in trachea.
Bleeding from airway.
Perforation of Tracheal and esophageal.
It also can cause pneumothorax.
Aspiration from lungs.
Also can cause chest pain.
subcutaneous emphysema.