Food & Beverage Traceability

Silica gels are used in chromatographic separations for analytical quality control of food as well as in the manufacturing of various food ingredients. Very fine particle-size silica gels are used as filter aids and clearing agents mostly in the beverage industry.

Zeochem offers a suite of product lines to support specific industrial needs.

ZEOprep: Irregular silica is one of the most widely used chromatography sorbents in the world. It is available in a wide range of pore and particle sizes with modifications from small to multi-ton quantities to meet application, performance and economic requirements.

ZEOsphere: Spherical silica is for normal phase and reversed-phase applications. Available products include classical reversed phases (e.g., C18, C8, C4, etc.) and ZEOsphere DRP Mixed-Mode silica for separation and purification of charged compounds. ZEOsphere silica is available in various pore and particle sizes as well as multiple modifications.

All our products are produced at ISO-9001 certified facilities. Strict quality control from raw material to finished product guarantees optimized chromatographic performance. Each step in the production process is closely monitored to minimize product variation and to secure high lot-to-lot finished product reproducibility.

Applications

Beer Industry

In the beer industry, porous silica gels are used as filter aids, as well as purification and clearing additives in batch applications. They can be used alone or in mixtures with other filter materials, mainly for the clearing and stabilization of beers. Large quantities of very fine particle silica gels are added to the beer to act as scavengers for proteins that cause turbidity and harm the stability of the finished product. Standard particle-size silica gels are added as efficient filter aids. We offer very fine silica gel in sufficient quantities to meet industry demands.

Cannabinoid (nonmedical)

Porous silica gels are used as classical stationary phase in chromatography-based separations of specific cannabinoids. CBD and other cannabinoids purification can be achieved using flash chromatography (normal-phase or reversed-phase pre-purification) and by reversed-phase (main purification-polishing).

While current separation techniques help clean up raw extracts and isolate cannabinoids with high purity, purity levels desired by the industry (> 90%) are not being met. This means there is a current need for a secondary purification step to remove the undesired co-extractants and provide the desired product purity with the highest recovery.

We offer a wide range of silica for flash chromatography cartridges (ZEOprep) and HPLC (ZEOsphere).

Lipids

Porous silica gels are used in industrial-size purification and separation columns for the purification and decolorization of triglycerides (i.e., from fish oils).

The separation of different forms of phospholipids requires chromatographic techniques where porous silica gels are a well-established stationary phase.

Nutraceuticals

Porous silica gels are used as classical stationary phase in chromatography-based separations of specific cannabinoids. Purification of advanced CBD and other cannabinoids can be achieved using flash chromatography (normal-phase or reversed-phase pre-purification) and reversed phase (main purification).

While current separation techniques help clean up raw extracts and isolate cannabinoids with higher purity, purity levels desired by the industry (> 90%) are not being met. This means there is a need for a secondary purification step to remove the undesired co-extractants and provide the desired product purity with the highest recovery.

We offer a wide range of flash chromatography products (ZEOprep) and products for the main reversed-phase purification (ZEOprep or ZEOsphere).

Vitamins

Vitamins are an important component of the daily diet. Some of the many vitamins of interest include vitamin A (retinol), vitamin B1 (thiamine), vitamin B2 (riboflavin), 25-OH vitamin D3, vitamin C, vitamin E (alpha-tocopherol) and vitamin K.

The separation of some isomere forms of vitamins requires chromatographic techniques and the use of unbonded or bonded silica gels.

We offer C18 modified ZEOprep (irregular silica) phases in different pore and particle sizes to meet the high purity requirements for vitamin applications.

Irregular shape chromatography silica gels are used as industrial column packing material for the purification of natural products, chemicals and active pharmaceutical ingredients, as well as packing material for flash cartridges and SPE (solid phase extraction).

Amorphous porous chromatography silica gels in spheroidal shape (microbeads) are used as industrial and analytical column packing material. They perform particularly well as packing material for flash columns.