Fallon said he's a big fan of the Sisterhood movies and asks if Bledel and her co-stars from the films — America Ferrera, Amber Tamblyn and Blake Lively — would do another movie. "I think we should absolutely do it," Bledel said. "We're working on it."

Fallon suggests an idea for a third installment in the franchise based on the best-selling books: The girls are older now and they've lost the pants and it goes so far that it turns into a horror movie. We'll put a pin in this idea.

In the fifth installment, Tibby has moved to Australia with her husband Brian and hasn't remained in contact with the other girls. Lena is an art teacher and not fully over a past flame. Bridget lives in San Francisco, and is ready to settle down with her longtime boyfriend Eric. Carmen is a successful actress working in New York City, dealing with her busy schedule. Tibby invites all the women to Greece with her because she has something big to reveal to them all that changes everything.

Bledel, Ferrera, Lively and Tamblyn have become real life best friends ever since they all met during the first Sisterhood film. They've kept in contact over the years, always getting together — with or without the magical jeans.

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Most recently, Ferrera and Tamblyn appeared on Spike's Lip Sync Battle. Tamblyn dressed up as Donald Trump and performed Color Me Badd's "I Wanna Sex You Up" and Ferrera performed Gloria Estefan's "Conga."