An interesting matchup of two young quarterbacks, JaMarcus Russell and Joe Flacco, and dueling twin defensive coaches, Rex and Rob Ryan. Rex's defense is built to stop strong rushing teams like the Raiders. RAVENS

Bills (5-1) at Dolphins (2-4), 10 a.m.

Buffalo's preseason promise is being fulfilled, thanks to the healthy return of quarterback Trent Edwards. Running back Marshawn Lynch could get his first 100-yard rushing day against the poor-tackling Dolphins. BILLS

Redskins (5-2) at Lions (0-6), 10 a.m.

Washington needs to keep this very simple: Attack Detroit's weak linebackers with a steady dose of Clinton Portis and Chris Cooley. REDSKINS

Chargers (3-4) at Saints (3-4) at London, 10 a.m.

Two good quarterbacks, Philip Rivers and Drew Brees ... two underachieving teams. Brees gets his first crack at team that dumped him in free agency in 2006. CHARGERS

Buccaneers (5-2) at Cowboys (4-3), 10 a.m. Channel: 2 Channel: 40

Dallas has lost three of four and now faces an extended period of quarterback Brad Johnson. Is this the end of the line for the Cowboys? It is this week, when they'll be outscored by Tampa's vertical offense. BUCCANEERS

Chiefs (1-5) at Jets (3-3), 10 a.m.

The Chiefs are a mess offensively; running back Larry Johnson won't play and they are down to third-string quarterback Tyler Thigpen. Jets quarterback Brett Favre is battling negative press but should rebound from a mistake-filled game against the Raiders. JETS

Rams (2-4) at Patriots (4-2), 10 a.m.

The switch to coach Jim Haslett has seen the Rams put together consecutive upsets over NFC favorites Washington and Dallas. But the Patriots' blowout win over the Broncos gives them major momentum. PATRIOTS

Cardinals (4-2) at Panthers (5-2), 10 a.m.

Second-best matchup of the week. Arizona leads the NFL in scoring while Carolina's defense is third best at limiting scoring. The Panthers are 4-0 at home. PANTHERS

Falcons (4-2) at Eagles (3-3), 10 a.m.

Philadelphia will bring the heat on rookie quarterback Matt Ryan. He will come up short as a desperate Donovan McNabb puts up some points. EAGLES

Bengals (0-7) at Texans (2-4), 1:05 p.m.

The Texans have consecutive victories, and they'll use their Mario Williams-fueled pass rush to attack quarterback Ryan Fitzpatrick (sacked seven times in Week 7). TEXANS

Browns (2-4) at Jaguars (3-3), 1:05 p.m.

The Browns' locker room appears split over comments made by Kellen Winslow, and that's rarely conducive to success. JAGUARS

MONDAY'S GAME

Colts (3-3) at Titans (6-0), 5:30 p.m. ESPN

Tennessee is on track to snap the Colts' five-year stranglehold on the AFC South and a win here gives the Titans a four-game lead. Injuries hamper the Colts while Tennessee is gaining strength behind its running game. TITANS