Inhibitor of MEK (MAP kinase kinase) activation. Maximal effects on MAP kinase activation, in cell culture, observed at 10-100 μM. Dilute directly from DMSO stock into buffered media, with stirring. Bovine serum albumin (6.6 mg/ml) has been found to prevent precipitation of PD-98059 in aqueous media (assayed with PD-98059 up to 100 μM).

References:

D.R.Alessi et al. J.Biol.Chem. 1995 270 27489
L.Pang et al. J.Biol.Chem. 1995 270 13585
The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.