Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of iloprost inhalation in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of iloprost inhalation in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving iloprost inhalation.

Pregnancy

Information about this iloprost-inhalation-route

Pregnancy Category

Explanation

All Trimesters

C

Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Apixaban

Ardeparin

Argatroban

Bivalirudin

Certoparin

Dabigatran Etexilate

Dalteparin

Danaparoid

Desirudin

Desvenlafaxine

Duloxetine

Edoxaban

Enoxaparin

Fondaparinux

Heparin

Lepirudin

Milnacipran

Nadroparin

Parnaparin

Phenindione

Phenprocoumon

Protein C

Reviparin

Rivaroxaban

Tinzaparin

Venlafaxine

Vilazodone

Warfarin

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

Asthma, severe, history of or

Bleeding problems, history of or

Breathing problems, history of or

Chronic obstructive pulmonary disease (COPD), history of or

Lung infections, acute or

Pulmonary edema (fluid in the lungs)—Use with caution. May make these conditions worse.

Hypotension (low blood pressure)—Should not be used in patients with this condition.

Kidney disease or

Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.