It is critical to apply YEOUTH Hyaluronic Acid Plus Vitamin C & Tripeptide 31 to a damp face or you will not see effective results. Use this product at night only. Spritz face with Yeouth Balancing Facial Toner (or water) onto a clean face. Smooth a dime sized amount of YEOUTH Hyaluronic Acid Plus Vitamin C & Tripeptide 31 into your skin. Rub it in thoroughly and allow to absorb. Then follow with YEOUTH L-22 daily moisturizer or your favorite anti-aging moisturizer. YEOUTH Hyaluronic Acid Plus Vitamin C Serum & Tripeptide 31 works beautifully on the neck, chest and the back of hands, too. If using YEOUTH Retinol Serum in addition to YEOUTH Hyaluronic Acid Plus Vitamin C & Tripeptide 31, we recommend applying both products back to back while your face is still damp. It does not matter in which order they are applied.