GenAge entry for SNCG (Homo sapiens)

Gene name (HAGRID: 140)

Potential relevance to the human ageing process

Main reason for selection

Entry selected based on evidence linking the gene product to the regulation or control of genes previously linked to ageing

Description

SNCG is a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. SNCG also appears to regulate BUB1B [1702]. While SNCG has been linked to cancer and CNS development [1083], its role, if any, in human ageing is unknown.