“Oprah, you can take a deep breath and hold it while the rest of us literally fight for our lives right now,” was one tweet.

On Sunday, she responded to the controversy in a Facebook Live video where she was joined by director Ava DuVernay.

“I couldn’t breathe after the election,” Oprah said. “I was expecting tension, awkwardness and strain. So, when I saw them sitting together, and I actually took a picture of the screen that said ‘President-elect Trump honored to meet Obama’. President Obama was being so gracious, and I heard Donald Trump say, ‘He’s a good man.’ I heard Donald Trump say, ‘I’m going to be seeking his counsel.’ I literally went... I can breathe now."

She then said it was a “mistake” to tweet what she did.

“My mistake, and what I know to be true, you can never talk about everybody," she said. "Even in your arguments with your husband and your children. Don't talk about what you should do, what you ought to do, what everybody else should do, only speak for yourself."

The TV titan is close friends with the Obamas and helped campaign for the president during his first campaign in 2008.

Comedian Wanda Sykes also faced outrage as she made anti-Trump remarks during a performance at Boston’s TD Garden Saturday night.

"I am certain this is not the first time we’ve elected a racist, sexist, homophobic president," Sykes said. “He's just the first confirmed one, that's it."

Her comments were met with thunderous boos which had the 52-year-old comic reportedly give the finger to the audience and shout: “f*** you, mother***er, f*** all of y’all.”

Sykes has not yet commented on the matter.

Comedian Dave Chappelle gained praise for his opening monologue on Saturday Night Livewhen he told the crowd: “In that spirit, I’m wishing Donald Trump luck and I’m going to give him a chance. And we, the historically disenfranchised, demand that he give us one, too.”

The reclusive comedian returned to television for the first time in more than a decade and instead of cracking jokes during his monologue, he seized the moment to discuss the feeling of many left disenfranchised by the results of the election.