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Application Note: Direct Determination of Fluoroacetate in Water by IC-MS

9 Feb 2012

This study presents an investigation to quantify fluoroacetate without prior derivatization or sample pretreatment. An ion chromatography (IC) method was developed with an MS detector. A fortified drinking water matrix was prepared following U.S. EPA guidelines and used to challenge the separation and robustness of the method. Method performance parameters such as linearity, calibration range, precision, accuracy, and detection limits were determined.