I dont know in which perspective Mylenium said it's possible...Would love to know it....If mylenium can explain

You said that you want to use your external drive to use the software on different computers and use the program,

In my point if view, this certainly cannot be done because there are lot of licensing files , database files, and registry entries made on the local drive , which cannot be moved to different computer , you will be moving the program but not the files to run it.

I installed the software on my E:\ drive and it worked fine but then I have to format the C:\ , and then when I tried to open teh application from the E"\ , it gave me the error , so I beleieve some native files do remain on computer to properly run the application