Digital technology is incorporated into nearly every facet of American life; it is integral to commerce, community, healthcare, food systems, transportation, education, media, entertainment, and employment. What emerging technologies are complicating the ability to verify authenticity and integrity in a digital world? And what emerging technologies enable the creation of systems of trust that enforce standards of authenticity, integrity, and security? How can partnerships between government, universities, and companies shape public policy to prioritize authenticity and integrity within systems, and who will be the stewards and custodians of such systems? This workshop will explore these questions and broadly examine the state of research and commercial applications of deep neural networks, distributed ledger technology, and quantum information systems within the context of how these emerging technologies challenge or enable an ability to establish systems of trust in the United States and throughout the global economy.