Most of the postadolescent women with acne in a retrospective review of 400 patients treated over a 4-year period improved with spironolactone treatment, with a low rate of side effects, according to the authors. “The vast majority of our patients improved on spironolactone, despite many previously failing other acne treatments,” …

Foamix Pharmaceuticals Ltd said on Monday its experimental acne treatment failed to meet one of two main goals in a late-stage study, pushing its shares down about 42 percent. However, the drug, FMX101, succeeded in a separate late-stage study, the Israel-based drug developer said. FMX101, is a topical version of …

Abstract Oral spironolactone has been used for over two decades in the dermatological setting. Although it is not generally considered a primary option in the management of female patients with acne vulgaris, the increase in office visits by post-teenage women with acne vulgaris has recently placed a spotlight on the …

AT SDEF WOMEN’S & PEDIATRIC DERMATOLOGY SEMINAR NEWPORT BEACH, CALIF. – While off-label use of spironolactone for the treatment of acne is quite common, it should be prescribed with special caution, advised Julie C. Harper, MD. “The vast majority of you write this for acne,” Dr. Harper, a dermatologist …

MINNEAPOLIS – Whether a young female patient has a refractory flare of inflammatory acne, or has a condition that can predispose to androgen excess, using a hormonal approach can be an effective management tool for controlling adolescent acne. During a presentation at the annual meeting of the Society for Pediatric …

SAN FRANCISCO – The room was packed for a talk about spironolactone and acne at the annual meeting of the American Academy of Dermatology. Several dozen people were turned away at the door because there weren’t any seats left. Dermatologists have heard that the drug is a good option for …

Young women taking spironolactone for hormonally mediated acne do not need to be monitored for hyperkalemia, say the authors of a study that showed no significant increase in the risk of the condition. The retrospective study in 974 otherwise healthy women taking spironolactone found the rate of hyperkalemia was 0.72%, …

The androgen receptor–blocker spironolactone is highly effective and safe but underused for the treatment of acne in women, according to Dr. Julie C. Harper. “The longer I’ve been in practice, the wider the age range where I use spironolactone as my drug of choice,” Dr. Harper said at the Hawaii …