MEDICAL NOTES

MEDICAL SEARCH ENGINE

SEARCH RESULTS

Post-exposure prophylaxis (PEP) has its greatest effect if begun within two hours of exposure, it is essential to act immediately. The prophylaxis needs to be continued for four weeks. Exposure must be immediately reported to designated authority and therapy administered. Never delay start of therapy due to debate over regimen. Begin with basic 2-drug regimen & expanded 3-drug regimn.

High pH is characterised by a decrease pCO2,primarly due to hypdrventilation.Compdnsatory renal responses lead to increase excretion and decreased serum bicarbonate levels.Sever respiratory alkalosis may result in light headedness parasthesia ,numbness,tetany ,convulsion.

Coronal ,saggital and lambdoid sutures of skull close during 2nd decade of life. One or more these sutures may close prematurely due to which growth of calvarium arrested in a direction right angles to fused sutures classification :-) 1 primary=present since birth with genetic basis 2 secondary=idiopathic hypercalcemia hypophosphatasia rickets,microcephaly diagnosis=prominent ridges over closed suture, asymmetry,confirmed by x ray of skull effects of craniosynostosis :- *cosmetic defects 1 dolichocephaly 2 brachycephaly 3 trigonocephaly 4 oxycephaly *proptosis and hypertelorism=growing brain within prematurely stenosed cranium exerts pressure causes displacement of greater wings of sphenoid bone
3) Growth of maxilla is interfered resulting in small nasopharynx.
4) arrested development of brain
5) optic atrophy.