Can I have my WD My Book Studio external hard drive firewired to my iMac and also hooked up to airport extreme via USB?

I have a WD My Book Studio that is capable of both firewire and USB connections. With the apple airport extreme, can I have the external hard drive firwired to the iMac (so I always have a reliable connection), and also have it connected to the airport extreme via USB? (so it can be accessed by other computers on the network?)