Lifecourse Determinants of Bone and Joint Disease

Abstract

The mission of the MRC Lifecourse Epidemiology Unit is to provide a centre of excellence which uses epidemiological methods to promote human health by delineating the environmental and occupational causes throughout the lifecourse of: (1) chronic musculoskeletal disorders (osteoporosis, osteoarthritis and sarcopenia); and (2) metabolic disorders (diabetes mellitus, obesity and cardiovascular disease). Through understanding these causes, we aim to develop population-based and high risk preventive strategies against these disorders. This programme will explore the origins of osteoporosis and its related fractures in the elderly, as well as osteoarthritis. These are the two commonest bone and joint disorders worldwide.

Technical Summary

Objectives: To (a) understand better the mechanisms which underlie the developmental origins of osteoporosis and other musculoskeletal disorders; and (b) develop intervention studies aimed at modifying later disease risk through nutritional and other interventions targeted at critical periods of development. Research proposals: The programme will address the developmental origins of osteoporotic fracture from molecule to population, using observational as well as interventional studies. Follow-up of participants in the Hertfordshire and Helsinki cohort studies will determine the growth trajectories of individuals at later risk of fracture, and explore the impact of these trajectories on bone size, geometry, mineral content, and volumetric density; the genetic contribution to these aspects of fracture risk will be studied through genome-wide screening as part of large international consortia. Further follow-up of children included in the Southampton Womens Survey will elucidate the parental influences on skeletal development during peri-conception, pregnancy and early postnatal life. Follow-up of these children through ages 6 and 8 years will extend our understanding of the relationship between maternal 25-hydroxyvitamin D status during pregnancy and childhood skeletal size, geometry and volumetric density. Our studies will permit exploration of interactions between prenatal and postnatal environmental influences such as physical activity (assessed using accelerometry), and diet (using questionnaires and biomarkers). Epigenetic mechanisms underlying the observed relationships between early environment and later bone health will be explored using samples of umbilical cord and placenta obtained from deliveries within SWS; DNA methylation status of key genes engaged in calcium transport, and maternal stress, will be related to childhood bone mass. A centrepiece of the programme will be the first randomised controlled trial to investigate whether supplementation of vitamin D during pregnancy serves to optimise skeletal development in the offspring (MAVIDOS). This aetiological trial will encompass sub-studies addressing intermediary outcome measures and the impact of vitamin D supplementation on other systems (body composition, immune function and respiratory development). Interventions to prevent osteoporotic fracture later in the lifecourse will be evaluated as part of the programme. Thus, in the MRC SCOOP trial, we test a novel methodology for risk stratification developed by the WHO in a large (n=11,500), pragmatic, randomised controlled trial. Finally, linkage with the NIHR Biomedical Research Unit in Musculoskeletal Science, University of Oxford, will permit development of a research theme addressing the lifecourse epidemiology of osteoarthritis; we shall study determinants of initiation and progression of this disorder, risk factors for arthroplasty failure, and the role of vitamin D in retarding the progression of OA. Impact: Musculoskeletal disorders have enormous health and economic impacts on society. Our research programme will permit the development of novel public health strategies to improve skeletal health throughout the lifecourse, and reduce osteoporotic fractures in future generations. Greater understanding of the epidemiology of osteoarthritis (the commonest joint disorder worldwide) will contribute to parallel strategies that reduce the incidence and morbidity associated with this disorder.

Mitchell PJ
(2015)
Life-course approach to nutrition.
in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Moon RJ
(2015)
Vitamin D and bone development.
in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Slide kit and video interviews based on science presented at 2015 World Congress in Osteoporosis

Type Of Art

Film/Video/Animation

Year Produced

2015

Impact

Widely viewed

Title

International Osteoporosis Foundation Video

Description

International Osteoporosis Foundation Video

Type Of Art

Film/Video/Animation

Year Produced

2014

Impact

International Osteoporosis Foundation Video

Title

International Osteoporosis Foundation:Slide kit and videos: ASBMR

Description

Production of slide kit and video interviews based on science presented at the 2015 ASBMR scientific meeting.

Type Of Art

Film/Video/Animation

Year Produced

2015

Impact

Widely viewed.

Title

LifeLab

Description

Picture

Type Of Art

Image

Year Produced

2014

Impact

LifeLab

Title

National Osteoporosis Society Video

Description

National Osteoporosis Society Video

Type Of Art

Film/Video/Animation

Year Produced

2014

Impact

National Osteoporosis Society Video

Title

Osteoarthritis webinar

Description

Osteoarthritis webinar

Type Of Art

Film/Video/Animation

Year Produced

2014

Impact

Osteoarthritis webinar

Title

WCO slide kit and videos 2016

Description

WCO slide kit and videos 2016

Type Of Art

Film/Video/Animation

Year Produced

2016

Impact

WCO slide kit and videos 2016

Title

WCO slide kit and videos 2017

Description

WCO slide kit and videos 2017

Type Of Art

Film/Video/Animation

Year Produced

2017

Impact

WCO slide kit and videos 2017

Description

ASBMR Professional Practice Committee

Geographic Reach

North America

Policy Influence Type

Membership of a guideline committee

Impact

Provision of bone densitometry with ISCD and IOF.

Description

Arthritis Research UK (Fellowships Committee)

Geographic Reach

National

Policy Influence Type

Influenced training of practitioners or researchers

Impact

As a member of the ARUK Clinical Studies Group in Metabolic Bone Disease, I reviewed several large, randomised controlled trials and fellowship applications answering important questions within musculoskeletal medicine.

Description

Can we identify patients with high risk of osteoporosis progression who will respond to treatment?

Improved and more efficient treatment of osteoporosis and vitamin D deficiency

Description

NICE

Geographic Reach

National

Policy Influence Type

Membership of a guidance committee

Impact

Co-authorship and citation in NICE Technology Appraisal on primary and secondary fracture prevention as well as NICE Clinical Guideline on fracture risk assessment. Publication of editorial (BMJ; 2012)

Description

NICE Guideline Development Group: Osteoporosis

Geographic Reach

National

Policy Influence Type

Membership of a guidance committee

Impact

Published guideline for treatment of postmenopausal osteoporosis.

Description

NICE OP

Geographic Reach

National

Policy Influence Type

Participation in a national consultation

Description

NOGG revised guidance

Geographic Reach

National

Policy Influence Type

Membership of a guideline committee

Impact

Guidance on assessment and treatment of osteoporosis

Guideline Title

National Osteoporosis Guideline Group

Description

NOGG; revised thresholds

Geographic Reach

National

Policy Influence Type

Citation in clinical guidelines

Impact

Optimized fracture risk assessment

Description

National Osteoporosis Guideline Group

Geographic Reach

National

Policy Influence Type

Membership of a guidance committee

Impact

National guideline on use of clinical risk factors and DXA assessment of bone density to target treatment for osteoporosis. Guideline published.

Description

National Osteoporosis Guideline Group 2017 (NCH)

Geographic Reach

National

Policy Influence Type

Participation in a advisory committee

Description

National Osteoporosis Society

Geographic Reach

National

Policy Influence Type

Participation in a national consultation

Impact

As Chairman of the Board of Trustees of this national charity, I gave evidence to the House of Lords Select Committee on Ageing, as well as contributing written responses on water fluoridation and musculoskeletal research over the period 2007-2009.

Intellectual input in design of study and development of protocol. On-going involvement in monitoring the study progress

Collaborator Contribution

Collaboration with a well-respected group

Impact

NIHR grant funding

Start Year

2008

Description

LPIN1 genotype and diet

Organisation

The Wellcome Trust Sanger Institute

Country

United Kingdom

Sector

Charity/Non Profit

PI Contribution

Contribution of anonymised phenotypic data

Impact

Publications. Pubmed ID: 18591397

Start Year

2007

Description

LPIN1 genotype and diet

Organisation

University of Cambridge

Department

MRC Epidemiology Unit

Country

United Kingdom

Sector

Academic/University

PI Contribution

Contribution of anonymised phenotypic data

Impact

Publications. Pubmed ID: 18591397

Start Year

2007

Description

LifeLab Southampton

Organisation

University of Southampton

Department

School of Medicine Southampton

Country

United Kingdom

Sector

Academic/University

PI Contribution

Our research findings have shown the importance of diet and lifestyle before children are even conceived, so we need to engage with children at schools to enable them to understand the importance of their behaviours now on their long-term health and that of their children

Collaborator Contribution

Enabled us to contribute more effectively to public engagement in science by getting our research findings communicated to teenagers in and around Southampton

Impact

Many public engagement activities with teenagers, with anecdotal marked improvement in the behaviour of some. Paper in preparation showing shifts in knowledge from before to after participating in the LifeLab activities.

Start Year

2007

Description

Lifecourse influences on women's smoking patterns

Organisation

Lancaster University

Department

Institute for Health Research

Country

United Kingdom

Sector

Academic/University

PI Contribution

Data provision, coding and cleaning, grant and paper writing

Collaborator Contribution

Data analysis, paper writing, grant writing

Impact

17708005, 16962221, 16476753

Description

Lung function in 6 year old children

Organisation

University of Southampton

Department

School of Medicine Southampton

Country

United Kingdom

Sector

Academic/University

PI Contribution

Data collection, grant and paper writing

Collaborator Contribution

Grant and paper writing. Data collection, analysis of samples

Impact

Papers now submitted

Start Year

2007

Description

MAVIDOS

Organisation

Medical Research Council (MRC)

Department

MRC Human Nutrition Research Group

Country

United Kingdom

Sector

Academic/University

PI Contribution

Research

Impact

Research

Start Year

2006

Description

MAVIDOS

Organisation

Medical Research Council (MRC)

Country

United Kingdom

Sector

Public

PI Contribution

Scientific collaboration

Collaborator Contribution

Scientific collaboration

Impact

2 abstracts

Start Year

2013

Description

MAVIDOS

Organisation

University of Oxford

Country

United Kingdom

Sector

Academic/University

PI Contribution

Research

Impact

Research

Start Year

2006

Description

MAVIDOS

Organisation

University of Sheffield

Country

United Kingdom

Sector

Academic/University

PI Contribution

Research

Impact

Research

Start Year

2006

Description

MAVIDOS Childhood Follow up

Organisation

University of Sheffield

Country

United Kingdom

Sector

Academic/University

PI Contribution

Recruitment to MAVIDOS 6 year follow-up in Sheffield

Collaborator Contribution

Recruitment to MAVIDOS six-year follow-up in Sheffield

Impact

N/A

Start Year

2016

Description

MAVIDOS Childhood Follow-up Oxford

Organisation

University of Oxford

Country

United Kingdom

Sector

Academic/University

PI Contribution

Recruitment of children to MAVIDOS six-year follow-up in Oxford

Collaborator Contribution

Recruitment of children to MAVIDOS six-year follow-up in Oxford

Impact

N/A

Start Year

2016

Description

MAVIDOS Oxford CVD

Organisation

University of Oxford

Country

United Kingdom

Sector

Academic/University

PI Contribution

Vitamin D in pregnancy and offspring cardiac structure and function

Collaborator Contribution

Vitamin D in pregnancy and offspring cardiac structure and function

Impact

Ongoing

Start Year

2015

Description

MRC Epidemiology Unit (EU), University of Cambridge

Organisation

University of Cambridge

Department

MRC Epidemiology Unit

Country

United Kingdom

Sector

Academic/University

PI Contribution

Research Collaboration

Collaborator Contribution

Research Collaboration

Impact

Clinical Impact

Start Year

2006

Description

MRC LLHA University College London

Organisation

University College London

Department

MRC Unit for Lifelong Health and Ageing

Country

United Kingdom

Sector

Academic/University

PI Contribution

Research Collaboration

Collaborator Contribution

Research Collaboration

Impact

Clinical Impact

Start Year

2009

Description

MRC SCOOP Trial

Organisation

University of Birmingham

Country

United Kingdom

Sector

Academic/University

PI Contribution

Research

Impact

Research

Start Year

2006

Description

MRC SCOOP Trial

Organisation

University of East Anglia

Country

United Kingdom

Sector

Academic/University

PI Contribution

Research

Impact

Research

Start Year

2006

Description

MRC SCOOP Trial

Organisation

University of Manchester

Country

United Kingdom

Sector

Academic/University

PI Contribution

Research

Impact

Research

Start Year

2006

Description

MRC SCOOP Trial

Organisation

University of Sheffield

Country

United Kingdom

Sector

Academic/University

PI Contribution

Research

Impact

Research

Start Year

2006

Description

MRC SCOOP Trial

Organisation

University of York

Country

United Kingdom

Sector

Academic/University

PI Contribution

Research

Impact

Research

Start Year

2006

Description

Metabolic syndrome in HCS

Organisation

GlaxoSmithKline (GSK)

Country

Global

Sector

Private

PI Contribution

Contribution of anonymised phenotypic data; statistical expertise

Impact

Multiple abstracts in this field

Description

Nigel Loveridge

Organisation

University of Cambridge

Country

United Kingdom

Sector

Academic/University

PI Contribution

Research Collaboration

Collaborator Contribution

Research Collaboration

Impact

Clinical Impact

Start Year

2006

Description

Nutrition BRU

Organisation

University of Southampton

Department

Faculty of Health Sciences

Country

United Kingdom

Sector

Academic/University

PI Contribution

Preparation of application, administration and conduct of some of the core projects

Collaborator Contribution

Allowed us to conduct complementary studies arising out of the Southampton Women's Survey

Peer led intervention package for young women aiming to optimize nutrition and physical activity

Type Of Technology

Webtool/Application

Year Produced

2017

Open Source License?

Yes

Impact

Multiple use in South Africa, New Zealand, Malaysia, Singapore

Description

"Meet the Expert Workshop" 2-4 December 2018, Kate Ward

Form Of Engagement Activity

Participation in an activity, workshop or similar

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Professional Practitioners

Results and Impact

Kate Ward led a "Meet the Expert Workshop" at the 2018 National Osteoporosis Society Annual Conference which took place in Birmingham from 2nd to 4th December 2018

Year(s) Of Engagement Activity

2018

Description

14th EUGMS Conference, Berlin, 10-11th October 2018

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Attendance and lecture at the 14th EUGMS held on the 10-11th October in Berlin

Year(s) Of Engagement Activity

2018

Description

2017 World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases, Florence

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Scientific Committee Chairperson for this event in Florence, Italy on 15th June 2017. The event was captured online, twitter, facebook and email

Year(s) Of Engagement Activity

2017

Description

2018 National Osteoporosis Society Annual Conference

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Professional Practitioners

Results and Impact

A number of MRC LEU investigators attended the 2018 National Osteoporosis Society Annual Conference. Young Investigator Awards were received by Beth Curtis, Millie Parsons, Michael Clynes and Nick Fuggle. Kate Ward led a Meet the Expert Workshop and Professors Cyrus Cooper and Nick Harvey also gave major invited plenary presentations. Nick and Kate are also members of the Conference Organising Committee. There was a lot of social media activity surrounding this event.

Year(s) Of Engagement Activity

2018

Description

28th Seah Cheng Memorial Lecture, Singapore, 15-18th September 2018

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Cyrus was invited to give the keynote address at the Academy of Medicine, Singapore on 'Osteoarthritis - from paediatric days to geriatric times'.

Year(s) Of Engagement Activity

2018

Description

45th European Calcified Tissue Society Conference in Valencia from 28-29th May 2018

Form Of Engagement Activity

A formal working group, expert panel or dialogue

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Provided lecture and attendance at the 45th European Calcified Tissue Society Conference

Year(s) Of Engagement Activity

2018

Description

9th International Conference on Osteoporosis and Bone Disease, China 2018

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Gave 2 lectures at the 9th International Conference on Osteoporosis and Bone Disease, chaired 2 events

Year(s) Of Engagement Activity

2018

Description

A blog welcoming Professor Cyrus Cooper to their new trustee

Form Of Engagement Activity

A press release, press conference or response to a media enquiry/interview

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Media (as a channel to the public)

Results and Impact

The Medical Research Foundation added to their blog to welcome Cyrus Cooper as their new trustee. Cyrus was nominated by the MRC and his term will be until 2020

Year(s) Of Engagement Activity

2017

Description

A press release issued for a paper which was published in the University of Southampton News and Medicalxpress

Form Of Engagement Activity

A press release, press conference or response to a media enquiry/interview

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Undergraduate students

Results and Impact

Press release on 'Relationships between markers of inflammation and muscle mass, strength and function: Findings from the Hertfordshire Cohort Study.

Year(s) Of Engagement Activity

2017

Description

ASBMR Annual Conference, Atlanta, USA - Plenary Lectures

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Industry/Business

Results and Impact

ASBMR Annual Conference, Atlanta, USA - Plenary Lectures

Year(s) Of Engagement Activity

2016

Description

ASBMR debate, Montreal

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Major international debate

Year(s) Of Engagement Activity

2015

Description

ASBMR nutrition WG

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

ASBMR nutrition WG, invited presentation of MAVIDOS study

Year(s) Of Engagement Activity

2015

Description

ASBMR presentation (BC)

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Beth Curtis presented MAVIDOS 4 year bone results

Year(s) Of Engagement Activity

2019

Description

American Society for Bone and Mineral Research in Montreal from 28th September to 1st October 2018

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

International Meeting in Montreal for the American Society for Bone and Mineral Research, presented a lecture and full attendance

Year(s) Of Engagement Activity

2018

Description

Appointment to non-executive director of hospital trust

Form Of Engagement Activity

A press release, press conference or response to a media enquiry/interview

Part Of Official Scheme?

No

Geographic Reach

Regional

Primary Audience

Professional Practitioners

Results and Impact

The University of Southampton Medicine News Page reported that Professor Cyrus Cooper has been appointed as non-executive director of hospital trust.

Year(s) Of Engagement Activity

2018

Description

Arthritis Research Sub-Committee in Chesterfield on 23rd May 2018

Form Of Engagement Activity

A formal working group, expert panel or dialogue

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Professional Practitioners

Results and Impact

Arthritis research sub-committee meeting in Chesterfield on 23rd May 2018

Year(s) Of Engagement Activity

2018

Description

Arthritis Research UK Pain Workshop, Wellcome Trust, London

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Professional Practitioners

Results and Impact

Arthritis Research UK Pain Workshop, Wellcome Trust, London

Year(s) Of Engagement Activity

2016

Description

Article appeared in Healio with quotes by Nick Harvey regarding findings in his paper which was published in July 2018

Form Of Engagement Activity

Engagement focused website, blog or social media channel

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Media (as a channel to the public)

Results and Impact

An article appeared in healio with quotes by Nick Harvey regarding the findings in his paper which was published in July 2018

Year(s) Of Engagement Activity

2018

Description

Article attracted great deal of media attention

Form Of Engagement Activity

Engagement focused website, blog or social media channel

Part Of Official Scheme?

No

Geographic Reach

Regional

Primary Audience

Media (as a channel to the public)

Results and Impact

Hill WD, Marioni RE, Maghzian O, Ritchie SJ, Hagenaars SP, McIntosh AM, Gale CR, Davies GA combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. Molecular psychiatry 2018/01/11 doi 10.1038/s41380-017-0001-5.This article attracted a great deal of media attention - as well as appearing in a number of newspapers it was tweeted by 467 people, was on 7 facebook pages, mentioned in 3 Google+ posts, picked up by 14 news outlets, 4 Reddit and 2 videos, plus 54 readers on Mendeley.

Year(s) Of Engagement Activity

2018

Description

Article entitled "higher inflammation in older age is linked to lower bone density" appeared in the University of Southampton medicine news and in the medicalexpress website

Form Of Engagement Activity

A magazine, newsletter or online publication

Part Of Official Scheme?

No

Geographic Reach

Local

Primary Audience

Undergraduate students

Results and Impact

Article entitled "higher inflammation in older age is linked to lower bone density" appeared in the University of Southampton medicine news and in the medicalexpress website

Year(s) Of Engagement Activity

2018

Description

Article for NRAS on Osteoporosis and Rheumatoid Arthritis (ED)

Form Of Engagement Activity

A magazine, newsletter or online publication

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Patients, carers and/or patient groups

Results and Impact

Review article designed to promote awareness of coexistence of comorbidity in RA, leading to enquiries from interested patients via the website

Year(s) Of Engagement Activity

2010,2015

Description

Article in National newspaper

Form Of Engagement Activity

A press release, press conference or response to a media enquiry/interview

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Public/other audiences

Results and Impact

The Guardian newspaper published an article entitled 'Murder Mystery to DNAL researchers bring science to life in schools.' The article covered the benefits of introducing school pupils to science in a laboratory environment.

Year(s) Of Engagement Activity

2017

Description

Article published on two websites

Form Of Engagement Activity

Engagement focused website, blog or social media channel

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

This article attracted some media attention and appeared on two websites and the University of Southampton enews. The articles were entitled 'Poorer health influences muscle strength in later life'.

Year(s) Of Engagement Activity

2017

Description

Article submitted for the 8th December edition of the Friday blog

Form Of Engagement Activity

Engagement focused website, blog or social media channel

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Media (as a channel to the public)

Results and Impact

Karen Walker-Bone and Cyrus Cooper submitted an article entitled 'Good work is good for us'.

Year(s) Of Engagement Activity

2017

Description

Articles on MAVIDOS findings appeared on website articles and facebook

Form Of Engagement Activity

Engagement focused website, blog or social media channel

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Articles on MAVIDOS findings appeared on the University of Southampton website, World News website; Publicnow.com. It was also mentioned on a number of Facebook pages including, University of Southampton; International Osteoporosis Foundation and Resilient Bones.

Year(s) Of Engagement Activity

2017

Description

Association of Physicians Annual meeting

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Professional Practitioners

Results and Impact

Presentation of MAVIDOS CTX data by Beth Curtis

Year(s) Of Engagement Activity

2019

Description

BBC Interview in Singapore for International News

Form Of Engagement Activity

A press release, press conference or response to a media enquiry/interview

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Media (as a channel to the public)

Results and Impact

Cyrus Cooper gave an interview on BBC World News addressing recent advances in the risk assessment and treatment of osteoporosis.

Year(s) Of Engagement Activity

2018

Description

BBC News: Vitamin D boosts child muscles

Form Of Engagement Activity

A press release, press conference or response to a media enquiry/interview

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Public/other audiences

Results and Impact

Extensive feedback

Year(s) Of Engagement Activity

2014

Description

BMFMS, Amsterdam

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

BMFMS, Amsterdam

Year(s) Of Engagement Activity

2016

Description

Blog for the University of Southampton

Form Of Engagement Activity

A broadcast e.g. TV/radio/film/podcast (other than news/press)

Part Of Official Scheme?

No

Geographic Reach

Local

Primary Audience

Professional Practitioners

Results and Impact

Regular broadcast while giving a talk in Geneva. It was one week after the general election. It made Cyrus more aware of the impact the election and Brexit would have on the work we do

Year(s) Of Engagement Activity

2017

Description

Blog on global outreach of the research of the MRC LEU

Form Of Engagement Activity

A broadcast e.g. TV/radio/film/podcast (other than news/press)

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Stimulating increased interest in research globally in the research of the MRC.

Year(s) Of Engagement Activity

2017

Description

Blog written by Cyrus Cooper and Nick Harvey which appeared in the Medically Spekaing section of the Unviersity of Southampton website

Form Of Engagement Activity

Engagement focused website, blog or social media channel

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Undergraduate students

Results and Impact

Cyrus Cooper and Nick Harvey wrote a blog which appeared in the "Medically Speaking" section of the University of Southampton website. Their blog was about the National Osteoporosis Society Annual Osteoporosis Conference, at which four members of the MRC LEU, Beth Curtis, Millie Parsons, Nick Fuggle and Michael Clynes all received young investigator awards.

Year(s) Of Engagement Activity

2018

Description

Bone Research Society Annual Scientific Meeting

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Professional Practitioners

Results and Impact

Beth Curtis presentation on bone turnover in MAVIDOS at BRS

Year(s) Of Engagement Activity

2019

Description

Bone Research Society Event Speaker and Organising Committee

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Part of the organising committee for the Bone Research Society Conference in Winchester from 27th - 30th June 2018.

Year(s) Of Engagement Activity

2018

Description

Bone Research Society Training Course, Oxford

Form Of Engagement Activity

Participation in an activity, workshop or similar

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Professional Practitioners

Results and Impact

Attended and ran a session at the Bone Research Society Training Course at Oxford in March 2018

Year(s) Of Engagement Activity

2018

Description

Bone Research Society, Edinburgh

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Major invited lecture

Year(s) Of Engagement Activity

2015

Description

British Orthopedic Research Society Keynote lecture (EMD)

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Professional Practitioners

Results and Impact

British Orthopedic Research Society Keynote lecture

Year(s) Of Engagement Activity

2017

Description

British Society for Rheumatology, Birmingham

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Major invited lecture

Year(s) Of Engagement Activity

2015

Description

British Society of Rheumatology Annual Meeting Manchester (ED)

Form Of Engagement Activity

A formal working group, expert panel or dialogue

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Professional Practitioners

Results and Impact

Chair of debate to discuss musculoskeletal aging, leading to greater awareness among colleagues and other interested parties

Year(s) Of Engagement Activity

2015

Description

CCA Meeting, Geneva - invited lecture

Form Of Engagement Activity

A formal working group, expert panel or dialogue

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

CCA Meeting, Geneva - invited lecture

Year(s) Of Engagement Activity

2016

Description

CTI manuscript press release (ME)

Form Of Engagement Activity

A press release, press conference or response to a media enquiry/interview

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Policymakers/politicians

Results and Impact

Calcified Tissue International manuscript on sarcopenia and dysmobility.

Year(s) Of Engagement Activity

2015

Description

Calcium and Vitamin D supplementation are not associated with risk of incident ischemic cardiac events or death: findings from the UK Biobank Cohort - press release

Form Of Engagement Activity

A press release, press conference or response to a media enquiry/interview

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Professional Practitioners

Results and Impact

Press release created a lot of media interest for this paper.

Year(s) Of Engagement Activity

2018

Description

Conference IOF Florence March 2017

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

The members of the Committee of Scientific Advisors of the International Osteoporosis Foundation (IOF) and the Scientific Advisory Board of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) are developing a very exciting Congress' scientific programme that will bring together the world's best in the field of musculoskeletal health and disease.

We really hope to welcome you in Krakow, Poland and that this Congress will move the field one step forward on all fronts; from new understanding of bone metabolism and pathology, to new strategies and options in prevention, diagnosis and treatment.

Year(s) Of Engagement Activity

2017

Description

Cyrus Cooper and Keith Godfrey - Clarivate Highly Cited Researchers

Form Of Engagement Activity

Engagement focused website, blog or social media channel

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Both Cyrus Cooper and Keith Godfrey received congratulations for being among 2018s highly cited researchers. They were included in the Clarivate Analytics listings and also mentioned on the University of Southampton website.

Year(s) Of Engagement Activity

2018

Description

Cyrus Cooper was interviewed for an article that was published in the Telegraph as a result of the paper that was published in the BMJ on Vitamin D.

Form Of Engagement Activity

A press release, press conference or response to a media enquiry/interview

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Media (as a channel to the public)

Results and Impact

Cyrus Cooper was interviewed for an article that was published in the Telegraph as a result of the paper that was published in the BMJ on Vitamin D. His comments included: Cyrus Cooper, Professor of Rheumatology at the University of Southampton and President of the International Osteoporosis Foundation who contributed to the study said that bone density was probably some two to three times better at predicting someone's risk of getting osteoporosis than their level of Vitamin D level. "I don't think this paper debunks the idea that Vitamin D is useful", he said. "It's just that it is a small determinant. You'd do some good if you make sure that your Vitamin D levels are okay." Commenting on the current UK advice for management and prevention of osteoporosis he said: "The current guidelines are appropriate however a bone density evaluation needs to be done as part of fracture risk screening".

Year(s) Of Engagement Activity

2018

Description

DOHaD World Congress, Cape Town

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Lecture

Year(s) Of Engagement Activity

2015

Description

Daily Mail vitamin D article

Form Of Engagement Activity

A press release, press conference or response to a media enquiry/interview

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Public/other audiences

Results and Impact

Interview on vitamin D to inform Daily Mail research

Year(s) Of Engagement Activity

2017

Description

Donation from Wessex Heartbeat of £200,000 in the LifeLab programme to help region's chldren lead a healthier life

Form Of Engagement Activity

Engagement focused website, blog or social media channel

Part Of Official Scheme?

No

Geographic Reach

Regional

Primary Audience

Undergraduate students

Results and Impact

News of the donation was on the University of Southampton website under medicine and lifelab news, daily echo website and newspaper, and deepsouth media.

Year(s) Of Engagement Activity

2017

Description

ECTS Conference, Rome. Keynote Lecture

Form Of Engagement Activity

A formal working group, expert panel or dialogue

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

ECTS Conference, Rome. Keynote Lecture

Year(s) Of Engagement Activity

2016

Description

ECTS, Salzburg 13-16 May

Form Of Engagement Activity

A formal working group, expert panel or dialogue

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

ECTS, Salzburg 13-16 May

Year(s) Of Engagement Activity

2017

Description

ESCEO Working Group, 20th March 2018

Form Of Engagement Activity

A formal working group, expert panel or dialogue

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Attendance and presented at ESCEO International Working Group on 20th March 2018

Year(s) Of Engagement Activity

2018

Description

ESCEO Working Groups, Geneva - Invited Lecture

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Vitamin D Meeting, London - Invited Lecture

Year(s) Of Engagement Activity

2016

Description

ESICON Congress, New Delhi. Plenary Lecture

Form Of Engagement Activity

A formal working group, expert panel or dialogue

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

ESICON Congress, New Delhi. Plenary Lecture

Year(s) Of Engagement Activity

2016

Description

EWGSOP2/EUGMS in Amsterdam on 4th June 2018

Form Of Engagement Activity

A formal working group, expert panel or dialogue

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Supporters

Results and Impact

Attendance and spoke at the EWGSOP2/EUGMS in Amsterdam on 4th June 2018

Year(s) Of Engagement Activity

2018

Description

Enews email University of Southampton, Faculty of Medicine and Daily Echo, Deccan Chronical and Medical Xpress

Form Of Engagement Activity

A press release, press conference or response to a media enquiry/interview

Part Of Official Scheme?

No

Geographic Reach

Local

Primary Audience

Professional Practitioners

Results and Impact

Sarah El Heis and Cyrus Cooper submitted paper entitled 'Maternal Stress and psychological distress preconception: association with offspring atopic eczema at age 12 months' to University of Southampton Faculty of Medicine and local newspapers. This paper received media attention from the University and the Daily Echo.

Year(s) Of Engagement Activity

2017

Description

Enews, University of Southampton: QQR renewal; and David Barker Research Prize (CC)

Form Of Engagement Activity

A magazine, newsletter or online publication

Part Of Official Scheme?

No

Geographic Reach

Regional

Primary Audience

Other audiences

Results and Impact

Enews, University of Southampton: QQR renewal; and David Barker Research Prize awarded to CC.

Attended Expert Panel Meeting on Sarcopenia in Boston from 12-14th November 2018

Year(s) Of Engagement Activity

2018

Description

Faculty of Medicine eNews Blog: CC

Form Of Engagement Activity

Engagement focused website, blog or social media channel

Part Of Official Scheme?

No

Geographic Reach

Regional

Primary Audience

Other audiences

Results and Impact

Faculty of Medicine eNews blog: CC

Year(s) Of Engagement Activity

2016

Description

Fake Food Event Feedback

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

Local

Primary Audience

Professional Practitioners

Results and Impact

Sian Robinson was one of the six panellists at the Fake Food event which took place at Lecture Theatre 1, SAB, Southampton General Hospital. The panel were asked questions by groups of local sixth formers who had been invited to the event.

Year(s) Of Engagement Activity

2018

Description

Findings from the paper 'Calcium and Vitamin D supplementation are not associated with risk of incident ischemic cardiac events or death' appeared in the Hippocratic Post and other media

Form Of Engagement Activity

A magazine, newsletter or online publication

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Media (as a channel to the public)

Results and Impact

Findings from the paper 'Calcium and Vitamin D supplementation are not associated with risk of incident ischemic cardiac events or death: Findings from the UK biobank cohort. J Bone Miner Res. 2018 May;33(5):803-811. doi: 10.1002/jbmr.3375, epub 2018 Feb 8'. appeared in the Hippocratic Post, on other websites, on 3 facebook pages, 34 tweets, and 1 blog.

Attendance and participation at the MRC Epidemiology Strategy Ref Group in Cambridge from 8th - 9th October 2018

Year(s) Of Engagement Activity

2018

Description

MRC Festival of Medical Research

Form Of Engagement Activity

Participation in an activity, workshop or similar

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Study participants or study members

Results and Impact

On 23rd June 2018 a number of MRC LEU staff (Prof Cyrus Cooper, Prof Hazel Inskip, Prof Elaine Dennison, Prof Sian Robinson, Gregorio Bevilcqua, Leo Westbury, Barbara Fariborz, Martin Stevens, Tina Horsfall, Holly Syddall, Kate Ward, Shirley Simmonds, Millie Parsons, Michael Clines, Vanessa Cox, Clare Harris, Harnish Patel and Ilsa Bloom) travelled to Hertfordshire for the MRC Festival of Medical Research where they held the Hertfordshire Cohort Study Open Day at Harpenden Public Halls. There were two sessions, one in the morning and the other in the afternoon. Many of the participants of the Hertfordshire study, their children and grandchildren attended the event which included a talk by Cyrus Cooper and hands on activities - refreshments were provided. An article appeared in MRC Life and another article about the open day was sent to Charlotte Campbell at UCL to be included in the CLOSER newsletter.

Year(s) Of Engagement Activity

2018

Description

MRC Festival of Medical Research, Southampton

Form Of Engagement Activity

Participation in an open day or visit at my research institution

Part Of Official Scheme?

No

Geographic Reach

Regional

Primary Audience

Public/other audiences

Results and Impact

MRC Festival of Science, Southampton

Year(s) Of Engagement Activity

2016

Description

MRC Grant for £134K

Form Of Engagement Activity

A press release, press conference or response to a media enquiry/interview

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Professional Practitioners

Results and Impact

Cyrus Cooper and Nick Harvey were successful in securing an MRC Grant to the value of £134k which will fund a new dual energy x-ray absorptiometry (DXA) instrument and Mechanograph technology.

Year(s) Of Engagement Activity

2018

Description

MRC LEU Centenary Event 2013

Form Of Engagement Activity

Participation in an open day or visit at my research institution

Part Of Official Scheme?

Yes

Geographic Reach

International

Primary Audience

Media (as a channel to the public)

Results and Impact

MRC Centenary Event open to the public, including presentations on work of the MRC over the last one hundred years, ending with a Q&A session. Led by Prof C Cooper and involving Unit staff.

Extensive feedback

Year(s) Of Engagement Activity

2013

Description

MRC LEU Science Week

Form Of Engagement Activity

Participation in an activity, workshop or similar

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Public/other audiences

Results and Impact

MRC LEU Workshop for Science Week, 14 March 2015

Year(s) Of Engagement Activity

2015

Description

Media attention from release of paper

Form Of Engagement Activity

A press release, press conference or response to a media enquiry/interview

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Media (as a channel to the public)

Results and Impact

'The impact of menopausal hormone therapy (MHT) on cardiac structure and function: insights from the UK biobank imaging enhancement study'. PLoS One 2018, March 8th.Within a few days of being published this paper was within the top 5% of articles for this phenomenal almetrics score. The attention score showed 75 news outlets, 1 blog, 15 tweeters from around the world. Many newspapers picked up the story, including the Sun, The Daily Mirror, The Daily Mail, The Daily Star. It also appeared on a number of websites: Science Daily; Mayo Clinic, Queen Mary University of London, The Citizen and Deccan Chronicle, as well as those of the newspapers.

Year(s) Of Engagement Activity

2018

Description

Media queries for GBD 2013 risk factor paper (CC)

Form Of Engagement Activity

A press release, press conference or response to a media enquiry/interview

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Policymakers/politicians

Results and Impact

Media enquiries from reporter regarding 'Global, regional and national comparative risk assessment of 79 behavioural, environmental and occupational and metabolic risks or clusters of risks in 188 countries 1990-2013; a systematic analysis for the GBD 2013'.

Year(s) Of Engagement Activity

2015

Description

Medicine News Roundup (CC)

Form Of Engagement Activity

A magazine, newsletter or online publication

Part Of Official Scheme?

No

Geographic Reach

Regional

Primary Audience

Media (as a channel to the public)

Results and Impact

Media: New research led by C Cooper, University of Southampton, reveals that older people with age-related loss of muscle mass and strength may be at greater risk of falling and bone fractures.

Year(s) Of Engagement Activity

2015

Description

Meeting of the MRC LEU Research Review Panel, 5th July 2017

Form Of Engagement Activity

A formal working group, expert panel or dialogue

Part Of Official Scheme?

No

Geographic Reach

Local

Primary Audience

Professional Practitioners

Results and Impact

Meeting of the MRC LEU Research Review Panel. This meeting took place at the MRC LEU and was chaired by Councillor Ivan White and presentations were given by Councillor Sarah Bogle, about her visit to LifeLab, Mary Barker on EACh-B and Elaine Dennison on The Hertfordshire Integration Study.

Year(s) Of Engagement Activity

2017

Description

Meeting with NOS President and Chief Executive of Canada

Form Of Engagement Activity

A formal working group, expert panel or dialogue

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Policymakers/politicians

Results and Impact

Meeting with the NOS President and Chief Executive of Canada at Dukes Hotel, London on 23rd March 2018

NEWS: Dr Christopher Bell led the largest sequencing based analysis to date of genetically driven epigenetic variation in the human genome.

Form Of Engagement Activity

Engagement focused website, blog or social media channel

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Media (as a channel to the public)

Results and Impact

NEWS: Dr Christopher Bell (MRC-LEU & IDS), in collaboration with King's College London and BGI Shenzhen, has led the largest sequencing-based analysis to date of genetically driven epigenetic variation in the human genome. This work, published in Nature Communications, has implications for the functional dissection of common disease associated regions, as well as the interpretation of DNA methylation population studies.

Year(s) Of Engagement Activity

2018

Description

NHS 70 Years

Form Of Engagement Activity

A formal working group, expert panel or dialogue

Part Of Official Scheme?

No

Geographic Reach

National

Primary Audience

Professional Practitioners

Results and Impact

NHS 70 years in London on 9th April

Year(s) Of Engagement Activity

2018

Description

NOS Public Lecture

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

Regional

Primary Audience

Public/other audiences

Results and Impact

Lecture

Year(s) Of Engagement Activity

2015

Description

New Forest Rotary Club Donation

Form Of Engagement Activity

Participation in an activity, workshop or similar

Part Of Official Scheme?

No

Geographic Reach

Local

Primary Audience

Schools

Results and Impact

New Forest Rotary Club enabled all Hounsdown School's Year 9 pupils to take part in the Lifelab programme thanks to a grant of £1,300 which funded the transport from school to the University of Southampton's LifeLab at the Biomedical Research Centre. The children thoroughly enjoyed the experience.

Year(s) Of Engagement Activity

2017

Description

New Twitter Account

Form Of Engagement Activity

Engagement focused website, blog or social media channel

Part Of Official Scheme?

No

Geographic Reach

Local

Primary Audience

Professional Practitioners

Results and Impact

Elizabeth Curtis sent an email to MRC LEU staff letting them know that the MRC LEU now has its own twitter account

Year(s) Of Engagement Activity

2017

Description

News Article (NCH)

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Oral presentation of MAVIDOS at ASBMR. Picked up scientific press in US.

This article, led by Dr Harvey, gives an overview of the important of osteoporosis and how it may be affected by diet.

Extensive feedback

Year(s) Of Engagement Activity

2013

Description

Paget's Information Event

Form Of Engagement Activity

Participation in an activity, workshop or similar

Part Of Official Scheme?

No

Geographic Reach

Regional

Primary Audience

Third sector organisations

Results and Impact

Approximately 50 patients attended for an information afternoon, with Professor Elaine Dennison, which sparked questions and discussion with patients reporting better knowledge of their condition.

Year(s) Of Engagement Activity

2018

Description

Paper appeared online in December 2017 after its press release, further media attention on 1.2.18 in MIMS

Form Of Engagement Activity

A magazine, newsletter or online publication

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

This paper first appeared online in December 2017 after its press release. However, in 2018 it received further media attention on 1.2.18 in MIMS with an article entitled GP-led screening reduces hip fracture risk in older women and on 2.3.18 in Medical Health News net an article entitled FRAX: a nuanced tool for predicting fracture risk. There were also 149 tweets and 28 retweets.

Year(s) Of Engagement Activity

2018

Description

Paper published on various websites, facebook and twitter

Form Of Engagement Activity

Engagement focused website, blog or social media channel

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Paper entitled 'Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis, submitted for publication in Nature Genetics by N Harvey and C Cooper. This paper received a great deal of attention from around the world on various websites, facebook and twitter.

Year(s) Of Engagement Activity

2017

Description

Paper received a great deal of media interest, appearing on a number of websites

Form Of Engagement Activity

Engagement focused website, blog or social media channel

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Media (as a channel to the public)

Results and Impact

McLachlan JJ, Gale CR.The effects of psychological distress and its interaction with socioeconomic position on risk of developing four chronic diseases. Journal of Psychosomatic Research. 2018; 109: 79-85.This paper received a great deal of media interest, appearing on a number of websites, including: University of Southampton, the Daily Mail, University Hospitals Southampton, the Sun, ITV News, Medical News Today, reachmd.com, managed health care executive.com, anxious minds, the star and archyworldys. An article also appeared in the Daily Echo.

Year(s) Of Engagement Activity

2018

Description

Paper receiving much media atttention on various websites, facebook and twitter

Form Of Engagement Activity

Engagement focused website, blog or social media channel

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Media (as a channel to the public)

Results and Impact

Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis, printed in Nature Genetics and receiving international attention

Presentation on vitamin D, bone turnover in pregnancy and offspring bone mass in MAVIDOS (E Curtis) at World Congress in Osteoporosis

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Presentation on vitamin D, bone turnover in pregnancy and offspring bone mass in MAVIDOS (E Curtis) at World Congress in Osteoporosis

Year(s) Of Engagement Activity

2018

Description

Presentation on vitamin D, epigenetics and bone mass in MAVIDOS (E Curtis), World Congress in Osteoporosis

Form Of Engagement Activity

A talk or presentation

Part Of Official Scheme?

No

Geographic Reach

International

Primary Audience

Professional Practitioners

Results and Impact

Presentation on vitamin D, epigenetics and bone mass in MAVIDOS (E Curtis), World Congress in Osteoporosis

Year(s) Of Engagement Activity

2018

Description

Presentations at St Swithans School

Form Of Engagement Activity

Participation in an activity, workshop or similar

Part Of Official Scheme?

No

Geographic Reach

Local

Primary Audience

Schools

Results and Impact

Approximately 10 sixth form students attended a talk about academic medicine which resulted in questions and discussion with follow up email correspondence, hosted by Professor Elaine Dennison on 3rd May 2018.

Year(s) Of Engagement Activity

2018

Description

Presented at the Australian and New Zealand Society for Sarcopenia and Fraility Research 2107 Annual Meeting