Rasmus mentioned on IRC how he ran the [command line] tests: simply renaming the ".phpt" test files as ".php", and invoking them through the CLI webserver. The SKIPIF sections get executed, but that doesn't affect the desired outcome of testing multiple HTTP requests with different input scripts. [Here] are some quick shell scripts I put together to automate testing the OCI8 extension with valgrind.

He uses the OCI8 extension as an example, showing how to set up these scripts to enable the execution of the tests, fire up the web server and execute Valgrind to help monitor the memory of the execution.