Tel-Aviv Sourasky Medical Centre

Tel-Aviv Sourasky Medical Centre (TASMC)- IsraelTel Aviv Sourasky Medical Center is a 1200‐bed Tertiary care teaching hospital, serving a population of approximately 1,000,000. It is affiliated to the Sackler Faculty of Medicine, Tel‐Aviv University. The Foundation for Medical Research, Infrastructure Development and Health Services is a separate legal entity established and dully registered under the Israeli law. The TASMC‐FUND is authorised to perform and execute research projects in the Tel‐Aviv Sourasky Medical Center whilst using its facilities. The project AIDA will be carried out by the Division of Epidemiology. The division has as a major task to improve our understanding of the development and spread of antimicrobial resistance, and thereby to design measures and adopt strategies to combat it. The division is responsible for infection control, health care epidemiology,hospital personnel health, and statistical services. The division also includes the Laboratory for Molecular Epidemiology and Antibiotic Research. The laboratory aims are also to improve methods of identifying AMR, to understand the spread of resistance, and of improved antimicrobial treatment, including the development of new antimicrobials and anti‐bacterial vaccines. Projects performed by the Division of Epidemiology have received grant support from the European Commission (MOSAR (FP6), SATURN, RGNOSIS (FP7)), Bi-National Israel‐America Science Foundation, the Sapir Foundation, the Center for Emerging Diseases, the Chief Scientist of the Israel Ministry of Industry and Commerce, and the Chief Scientist of the Israel Ministry of Health.Main tasksTASMC will perform the microbiology studies for WP1 (Multicenter, open‐label, randomized clinical trial to compare colistin alone vs. colistin plus imipenem for severe infections caused by carbapenem‐resistant bacteria)

Previous experience and key personnelYehuda Carmeli (MD, MPH) is head of the Division of Epidemiology. Dr Carmeli, has received his training in infectious diseases and in public‐health at Harvard University. He has over 180 peer‐reviewed publications in the area of AMR and hospital epidemiology in various journals (including JAMA, Circulation, Nature Microbiology,Archives of Internal Medicine, and Antimicrobial Agents and Chemotherapy). He serves at the editorial board of Clinical Infectious Diseases, Infection Control and Hospital Epidemiology, and Current Opinion in Infectious Diseases. He is the chair of the Israeli Ministry of Health Center on Nosocomial Infections and Antibiotic Resistance. Dr Carmeli is a WP leader in the FP6 MOSAR and FP7 SATURN and RGNOSIS projects on antimicrobial resistance.