opiate analgesic (opioid analgesic) any of a class of compounds that bind with a number of closely related specific receptors (opioid receptors) in the central nervous system to block the perception of pain or affect the emotional response to pain; such compounds include opium and its derivatives, as well as a number of synthetic compounds, and are used for moderate to severe pain. Chronic administration or abuse may lead to dependence.

tra·ma·dol

(trah'mă-dol),

An analgesic drug with a mechanism of action that is unusual in that one optic isomer exerts typical opioid-type effects and the other isomer interacts with the reuptake and/or release of norepinephrine and serotonin in nerve terminals.

tramadol

/tra·ma·dol/ (tram´ah-dol″) an opioid analgesic used as the hydrochloride salt for the treatment of pain following surgical procedures and oral surgery.

tramadol

(trăm′ə-dôl′)

n.

A synthetic analgesic, C16H25NO2, used in its hydrochloride form to treat moderate to moderately severe pain. It is structurally similar to codeine and has both opioid and nonopioid effects.

tramadol

a central analgesic.

indications It is used to manage moderate to severe pain.

contraindications Factors that prohibit its use are known hypersensitivity to this drug or acute intoxication with any central nervous system depressant.

tramadol

tramadol

A centrally-acting synthetic opiate pain-killing drug. It is less likely to cause respiratory depression, constipation, euphoria and addiction than many of the ipioid agonists. It is currently the fourth most commonly prescribed analgesic in the world. Brand names are Tramake, Zamadol and Zydol.

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