Microcosm: The Book

Science writer Peter Dizikes reviews my book Microcosm for the New York Times. It's great to see that he gets it--i.e., he understands what I'm trying to do with E. coli in the book. I actually appreciate that more than a positive review. Fortunately, he liked the book, too, calling it engrossing, vivid, and adroit. Check it out.

The strange thing about E. coli, as I explain in my book Microcosm, is that it has played a central part not just in the modern science of life, but in the political conflicts over life. It may come as a surprise that a humble gut germ could get involved in culture wars. But you need only consider how much attention creationists have been lavishing on E. coli in recent years, hoping to use it as evidence that life did not evolve--that it was created or designed instead.
Originally, creationists claimed that structures in E. coli showed clear evidence of being created--they were complex, made…

The British edition of Microcosm is coming out on July 3 (Brits can pre-order here, and here's a link for Americans). In conjunction with its publication, the Telegraph asked me to explain why I love E. coli so. Here's why.

It's nice to get book reviews in both the popular press and academic journals. I hope everyone will read my books, but I also hope that scientists will consider them good science. And, speaking of Science, the journal of said name just published a lovely review of Microcosm by the evolutionary biologist Daniel Rankin:
A popular science book on E. coli may not sound like the most interesting read. However, Microcosm is just that. The next time you hear of an outbreak of nasty E. coli on the news, spare a thought for this minute creature, which has arguably helped advance humanity far further…

Hey Angelenos! I hope you can come out to catch my next talk about Microcosm. It's part of the Zocalo lecture series. I'll be talking next Wednesday, June 25, at 7:30 pm at the Skirball Cultural Center. Here are the details.

My recent post about a striking new experiment in evolution (E. coli evolving the ability to eat a new kind of food) is still drawing lots of commenters and links. Very cool! Not so cool are the claims that this experiment is evidence of creationism, made by people who have not actually read the paper itself. Unfortunately, the paper is behind a subscription wall at the journal. Fortunately, the scientists have posted it on their own web site (pdf link). So go, read, and digest.
I'm also hoping that Zachary Blount, the grad student who pored over the trillions of E. coli in this experiment,…

The field of biology has been wildly successful by taking what's called a reductionist approach, i.e., you tackle a small problem in isolation in order to gain insight into larger questions. In his new book, Microcosm: E. coli and the New Science of Life, Science writer Carl Zimmer took that reductionist approach and applied it to a pretty big issue: life itself. For Zimmer, the system that serves as a model of all life, and of humanity's often uncomfortable relationship to it, is the unprepossessing gut bacteria, Escherischia coli. Covering all of life is a big task, and Zimmer made the…

Thursday I'll be heading up the road to talk about Microcosm at one of my favorite bookstores: RJ Julia in Madison CT. The talk is at 7, and it's free. And for once I don't have to fly to a talk. Here are the details. Hope to see some Connecticut Loom-readers there.

Imagine that mad scientists defied nature and violated the barriers between species. They injected human DNA into non-human creatures, altering their genomes into chimeras--unnatural fusions of man and beast. The goal of the scientists was to enslave these creatures, to exploit their cellular machinery for human gain. The creatures began to produce human proteins, so many of them that they become sick, in some cases even dying. The scientists harvest the proteins, and then, breaching the sacred barrier between species yet again, people injected the unnatural molecules into their own bodies…

A reader of Microcosm blogs:
I am literally only 12 pages in, yet Zimmer has already managed to make me catch my breath, clutch the book to my chest, and feel my eyes get a little moist from the emotional impact of it all.
I wonder what a couple hundred more pages will do...

I spoke Tuesday on Seattle, and there's proof now! Alan Boyle, MSNBC's science guru, wrote a great piece on both the talk and the subject, my book Microcosm. Meanwhile, folks from Real Science were taping, and now you can listen to the talk at their web site. If I had lots of free time, I'd combine the audio with my slides and post them, but I'm swamped for now.
I also completely spaced out last week and forgot to mention that I was interviewed on the Skeptic's Guide to the Universe. You can listen here.

I'm back at last from the west coast leg of the Microcosm tour.
Portland had a cloudy, melancholy charm, and at Powell's I gave a reading in front of a collection of hand-made black velvet paintings from the nearby Velveteria. When the audience's eyes drifted off of me, I couldn't tell if they were lost in thought or distracted by Jimi Hendrix or a smoking clown.
The next day I headed for San Francisco, where I talked to Moira Gunn for her show Tech Nation (link to come). Then I had lunch with Kirsten Sanford, who will be interviewing me on tomorrow's edition of This Week In Science. Then…

The microbial march continues! I'll be in Seattle today, giving two talks on Microcosm: E. coli and the New Science of Life. The first is a 1:30 talk at Microsoft Research. Then I'll be giving a public talk at Town Hall at 7:30 as part of their science series.

One of the most important experiments in evolution is going on right now in a laboratory in Michigan State University. A dozen flasks full of E. coli are sloshing around on a gently rocking table. The bacteria in those flasks has been evolving since 1988--for over 44,000 generations. And because they've been so carefully observed all that time, they've revealed some important lessons about how evolution works.
The experiment was launched by MSU biologist Richard Lenski. I wrote about Lenski's work last year in the New York Times, and in more detail my new book Microcosm. Lenski started off…

The French biologist Jacques Monod once famously said, "What is true for E. coli is true for the elephant." At the time, he was referring to the universal rules of molecular biology--of DNA and proteins, for example, that are the same from one species to another. As scientists in the mid-1900s figured out the workings of E. coli, they were also figuring out the workings of life in general. In my new book Microcosm, I make the case that Monod's words were more true than even he realized. In the Boston Globe today, I explain how scientists used to think that there was one big difference between…

One of the best things to come out of blogging is the blog book club. (See, for example, the book club at Talking Points Memo.) In the bad old days, the only way writers could respond to books was with a one-shot book review. A blog book club, on the other hand, allows writers to have public conversations about books and the issues they raise. It also makes room for readers to get into the discussion as well.
Unfortunately, until now blog book clubs have mostly been dedicated to politics. Scienceblogs is now rectifying this imbalance with the launch of the Scienceblogs Book Club. And, oh…

I'm heading cross-country to talk about Microcosm. First stop--Powell's bookstore in Portland tonight. Never been there before, so I'm looking forward to a bibliophile's pilgrimage. Hope to see Portlanders there!

E. coli is, arguably, the one species that scientists know best. If you type the name "Escherichia coli" into PubMed, the database of the National Library of Medicine, you'll get over a quarter of a million titles of scientific papers. Scientists have sequenced about 30 genomes of different strains of E. coli. It's the microbe of choice for those who want to figure out how to tinker with life. There's one problem with all this attention--how are scientists supposed to make sense of all this data? Scientists have created sites to aggregate E. coli data in one place. The newest and broadest…

Pagination

Donate

ScienceBlogs is where scientists communicate directly with the public. We are part of Science 2.0, a science education nonprofit operating under Section 501(c)(3) of the Internal Revenue Code. Please make a tax-deductible donation if you value independent science communication, collaboration, participation, and open access.

You can also shop using Amazon Smile and though you pay nothing more we get a tiny something.

More reads

As I write this, I'm told that there are eleven water cannon vehicles heading to the disaster-stricken Fukushima Daiichi nuclear power plant, to attempt to cool down nuclear material that is exposed and exuding (I dare not use the word "leaking" lest I be thought an alarmist) radiation at a rate that seems to be as alarming to the engineers and nuclear experts on the scene as it is assuaging to…

Prepare yourself.
The Te Papa Museum of New Zealand has a new specimen locked in a vault: a colossal squid that will be thawed and dissected (they think!) on streaming video.
Here is the necromantic chamber.
Wait! No protective runes, no array of emergency thuribles, no pentagram, no mysterious idols of jade and obsidian? This may not go well.