Sanford Burnham Prebys Medical Discovery Institute (SBP) is an non-profit medical research institute with locations in La Jolla, California and Orlando, Florida. There are more than 850 scientists at SBP blending cutting-edge fundamental research with robust drug discovery to address unmet clinical needs in the areas of cancer, neuroscience, immunity, and metabolic disorders.

Sanford Burnham Prebys Medical Discovery Institute

For the modern biologist, large-scale OMICs studies—which map all of the genes, proteins, RNA and more that underlie a biological system—are standard tools of the trade. But interpreting these big-data outputs to generate ...

Investigators at Burnham Institute for Medical Research (Burnham), Mount Sinai School of Medicine (Mount Sinai), the Salk Institute for Biological Studies (Salk) and the Genomics Institute of the Novartis Research Foundation ...

Investigators at Burnham Institute for Medical Research have identified novel cleavage sites for the enzyme caspase-3 (an enzyme that proteolytically cleaves target proteins). Using an advanced proteomic technique called ...

Investigators at Burnham Institute for Medical Research, University of California, San Diego, The Scripps Research Institute, Genomics Institute of the Novartis Research Foundation and other institutions have constructed ...

Dieter Wolf, M.D., and colleagues at Burnham Institute for Medical Research (Burnham) have illuminated how competition between proteins enhances combinatorial diversity during ubiquitination (the process that marks proteins ...

Researchers at Burnham Institute for Medical Research (Burnham), University of Texas Southwestern Medical Center and University of Maryland have demonstrated that an enzyme that is essential to many bacteria can be targeted ...

Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) ...

Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specific microRNAs (non-coding RNAs that interfere with gene expression) reduce HIV replication and infectivity in human T-cells. In particular, ...

Gregg Duester, Ph.D., professor of developmental biology at Burnham Institute for Medical Research (Burnham), along with Xianling Zhao, Ph.D., and colleagues, have clarified the role that retinoic acid plays in limb development. ...

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