This is a quasi-experimental study. Purpose was to investigate effect of education on health behaviors of mothers of children under 6-12 years old, about prevention of typhoid. A sample of 60 mothers selected and then divided to two groups. One group had typhoid and the other didn't have typhoid. Data were collected by a questionnaire with two parts. The first part included demographic and social characteristics of participants, and the second part included some questions about health behaviors related to typhoid. Using Mcnemar statistical test, results showed that education increased mothers' information with 95 percent confidential interval. Relationship between effect of education and variables such as age, marital status, literacy, number of children and so on were determined by squared T test. Differences between effects of education in two groups were determined by T test.