Purpose — to improve the diagnosis and prognosis of postpartum endometritis by applying the method of fluorescence spectroscopy.

Materials and methods. The study involved 120 women with postpartum endometritis and 38 women with uncomplicated postpartum period (control group). Fluorescence spectral characteristics of blood serum, including repeat testing in the course of treatment, were studied.

Results. It was shown that significant (p<0.05) prognostic factors of postpartum endometritis are the presence of inflammatory diseases of the lower genital tract, anomalies of labor activity and TORCH-infections. It was established that the decrease in fluorescence intensity and the presence of long-wavelength shift are reliable diagnostic markers of inflammatory diseases, including postpartum endometritis (p<0.05). Comparison of the sensitivity, specificity, positive probability ratio, positive and negative predictive values of leukocytosis and C-reactive protein with reliable markers of inflammatory diseases by means of the method mentioned above, were obtained the best results.

Conclusions. Spectral-fluorescent properties of blood serum are the reliable markers for the diagnosis of inflammatory diseases in obstetric-gynecologic practice.