The cancer tissue page shows antibody staining in 20 different cancers. The overall cancer tissue staining statistics shows the fraction of patient samples with high, medium, low or not detected (as described by the color-coding scale in the box to the right), using all the available antibodies to the protein targets encoded by this gene. The assay and annotation is described here.

The cancers can be ordered histologically or alphabetically.

For each cancer, the staining for each available antibody is reported as the fraction of samples with antibody staining level high, medium, low or not detected (as described by the color-coding scale in the box to the right). The length of the bar represents the number of patient samples analyzed (max=12 patients).
By clicking on a cancer tissue, the detailed staining data for that cancer is available, including annotated images.

At the bottom of this page, a summary for the cancer staining for each antibody is given, together with the literature conformity for the staining pattern revealed by that specific antibody.

A majority of malignant cells showed moderate cytoplasmic staining with a granular pattern, often accompanied with nuclear staining in a fraction of the cells. Several prostate cancers were strongly stained, while most testicular, urothelial, renal and hepatocellular carcinomas were weakly stained or negative.

Mucinous ovarian cancers and fractions of cells in cases of colorectal cancers displayed strong staining. A majority of testicular cancers as well as a few breast, prostate, skin and urothelial cancers displayed moderate cytoplasmic positivity. Subsets of cells in malignant gliomas showed moderate nuclear staining. Malignant cells in general showed weak staining or were negative.