Bioinformatics is an emerging field of science emphasizing the application of mathematics, statistics, and informatics to study and analysis of very large molecular biological (mostly, genetic and genomic) systems (data sets). In a comparatively broader setup of large biological systems without necessarily having a predominant genetic undercurrent, and having genesis in biometry to biostatistics, biostochastics has evolved as the primary vehicle for the much needed statistical reasoning. It is intended to point out the genuine need for statistical reasoning in this evolving interdisciplinary field, and in that way, to appraise the limitations of current (mostly, algorithm based) statistical resolutions.