Crohn's and pregnant

Humiria while pregnant.

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itsakinmanbaby wrote:

So I'm reading online that if you are humiria you have to stop in your third trimester bc the baby immune system is building and they don't want anything suppressing that ? Has anyone been on it ? When did you stop ?

I'm on it and in the same boat. I really dont want to stop because with my first pregnancy, I was on cimzia the whole time with no issues. Then 4 months postpartum mhy crohns flared and I had to go on entocort and increase cimzia. That failed and I tried remicade. It didn't help. So I started humira right when I found out I was pregnant. My gi doc is very leary of taking me off because she thinks I will make antibodies by the time I go back on.

I'm going to look on the infant risk center and possibly call and see what they say about not going off.

I was on infliximab in my last pregnancy and on humira for this one and it was the same thing. I stopped at 5 months pregnant and was fine but flared 3 months after baby- I had choice of going back on meds earlier but didn't so got a flare. My sister was on same drug up to few weeks before birth and started back two weeks after. So I think they prefer to stop it earlier but no rule if your at high risk of or in a flare. The big thing is the baby's immunity may be a little suppressed so they cannot have any live vaccines.

Also on humira for two years prior to pregnancy, my GI specialist agreed that it's best to stop around 6 months pregnancy and continue again once breast feeding has stopped or if I decide not to breast feed at all. We decided to try and treat flares with budesonide and prednisone if necessary. My specialists concern was the humira would depress babies immune system which he wanted to avoid ( especially since I'm due any day now and winter germs) but I've heard of some people continuing no matter what due to risk of flares, I've only have one bad flare in my disease history but I have relatively mild symptoms ( but severe inflammation, explain that one!?) so we decided that it would be ok for me to go off during the final months.

My OB and GI doctors both were fine with me staying on Humira throughout my entire pregnancy, and I breastfed for 12.5 months on Humira. My daughter did not receive any live vaccines for the first 6 months (Rotovirus is the only one), but otherwise was able to be fully vaccinated. She is 19 months and has never had more than a few minor colds. Humira is a large molecule drug, too large to pass into the breast milk. My OB, 2 lactation consultants, and my daughter's pediatrician were all OK with breastfeeding while on Humira. Obviously, listen to your doctors, but I would also do some research and possibly get second opinions. A healthy mom is important to take care of the baby. I did not flare at all during pregnancy or after, and healed fine from a C/S. This is my second Humira pregnancy, and I will be staying on throughout, and breastfeeding after. Good Luck!

Thank you all for the information. I've been on Humira since May. Originally my GI doctor said I could come off when I got pregnant but after a recent colonoscopy said that I would need to continue during pregnancy. I'm due in Sept and incredibly concerned about everything!

I was on humira my entire pregnancy- both my GI and my OB agreed that it's not worth the risk of a flare up in order to pretext the babies immune system which will be fine anyways. The only real repercussions is that the baby can't have any live vaccines until 6 months old- and that only includes one vaccine- rotavirus. Which us nut really necessary anyways according to the pediatrician.

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