Mutation details: A 6.5 kb genomic DNA fragment of the Ckmm gene containing the promoter and enhancer 1, untranslated exon 1, 3kb of intron 1 including the enhancer 2 region, and the first 16 bp of exon 2 drives expression of cre. Cre is active in heart and skeletal muscle starting approximately at embryonic day 13.
(J:51964)