Title (de)

Title (fr)

Publication

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US 9405868 W 19940525

US 6765793 A 19930526

Abstract (en)

[origin: WO9427957A1] Chemical derivatives of nitric oxide are provided which are stable indefinitely in oxygen-containing solutions until photolysis, whereupon they release NO. These compounds have the general formula (I): A-N<+>(O<->)=N-O-B wherein A is typically a nitrogen- or oxygen-containing substituent and B is a group labile to photolysis. The compounds are stable and inert in oxygenated aqueous solutions, but release NO upon illumination. Given the ease with which the intensity, timing and location of illumination may be controlled, these compounds are particularly useful in investigating the biological effect of NO with much higher spatial or temporal resolution than heretofore possible.