Event-related dynamics of glutamate and BOLD signal at 3 T in a repetition suppression paradigm

Dace Apvalka 1 , Andrew Gadie 1 , and Paul Gerald Mullins 1

1
Psychology, Bangor University, Bangor,
Gwynedd, United Kingdom

Improvements in scanner technologies and data
acquisition and analysis methods allow magnetic
resonance spectroscopy (MRS) techniques to detect
neurochemical concentration changes associated with
neural activity. This functional MRS (fMRS) technique is
gaining increasing interest in neuroscience, however a
debate exists as to whether stimulus related changes of
metabolites might be reliably detected using fMRS, and
if it is possible to do so at 3T. This study presents
event related dynamics of glutamate (Glu) and
blood-oxygen-level-dependent (BOLD) signal at 3T in a
repetition suppression paradigm.

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