The transcription factor GAGA, encoded by the gene Trl, controls expression of many Drosophila melanogaster genes. We have compiled the presently largest sample (120 sites) of published nucleotide sequences with experimentally confirmed binding to GAGA protein. Analysis of the sample has demonstrated that despite an apparent structural diversity of the GAGA… (More)

It is known that a lot of genes having a distinct expression pattern require the complex system of transcription regulation. The regulatory regions of such genes can include not only the 5'-flanking regions, but also other regions, particularly their intron sequences. The Drosophila melanogaster Trithorax-like (Trl) gene, encoding the GAGA protein, is one… (More)

The development of dorsal appendages of the chorion (specialized structures in the D. melanogaster egg which look like elastic tubes and ensure the breathing of the developing embryo) is an attractive model for the study of genetic mechanisms of the development of organs and tissues, whose generation is based on transformation of the epithelial tissue in… (More)

Insects are surprising in the size and diversity of taxa, members of which are considered to be one of the best-adapted and most evolutionary successful living organisms. Insects are characterized by diversity and an abundance of adaptations to environmental conditions; the members of this class occupied different ecological niches, and it is possible to… (More)

Insects is a taxon surprisingly rich with species and varieties, and its representatives are considered as the most fitted and "evolutionary successful" living things. Insects are distinguished by diversity and abundance of adaptations to environmental conditions, representatives of this class inhabit different ecological niches, they can be found… (More)

Multifunctional optogenetic systems are in high demand for use in basic and biomedical research. Near-infrared-light-inducible binding of bacterial phytochrome BphP1 to its natural PpsR2 partner is beneficial for simultaneous use with blue-light-activatable tools. However, applications of the BphP1-PpsR2 pair are limited by the large size, multidomain… (More)