Previous HGNC Symbols for NPFFR1 Gene

Previous GeneCards Identifiers for NPFFR1 Gene

Summaries for NPFFR1 Gene

GeneCards Summary for NPFFR1 Gene

NPFFR1 (Neuropeptide FF Receptor 1) is a Protein Coding gene.
Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors.
GO annotations related to this gene include G-protein coupled receptor activity and neuropeptide receptor activity.
An important paralog of this gene is NPFFR2.

UniProtKB/Swiss-Prot for NPFFR1 Gene

Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Tocris Summary for NPFFR1 Gene

Neuropeptide FF/AF (NPFF) receptors are a group of Gi/Go-protein-coupled receptors that are divided into two subtypes; NPFF1 and NPFF2. NPFF receptors have been implicated in hormonal modulation, regulation of food intake, thermoregulation and nociception.

Function for NPFFR1 Gene

Products:

Molecular function for NPFFR1 Gene

UniProtKB/Swiss-Prot Function:

Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.