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Items that can be consumed by being held during battle (without knock off or fling): all herbs, all gems, all seeds, all status curing berries, all healing berries, all damage reducing berries, all stat raising berries, absorb bulb, berserk gene, cell battery, luminous moss, snowball, weakness policy, focus sash, adrenaline orb, air balloon, eject button, red card, leppa berry, custap berry, jaboca berry, rowap berrysourcesourcesource
Items that may only be used once but don't disappear: all mega stones, all z-crystalssourcesource