Here you will find information about Research groups in the PathoGenoMics fields from the ERA-NET partner countries (Austria, Finland, France, Hungary, Israel, Latvia, Portugal, Slovenia and Spain). This information is supposed to support cooperation between researchers from different European countriesand thus enhance the development of a European Research Area for PathoGenoMics .

The following information is available and can be searched for:

researcher names

Institution of the respective researcher, city and country of his/her institution

Borreliae, borreliosis, Lyme disease, borrelia arthritis, immune evasion, neutrophil, dendritic cell, mouse model, CD38, TNF-alfa
Our first aim is to understand the mechanisms by which borrelia evades the first line immune defence and disseminates causing a multi-organ infection. Our second aim is to clarify the mechanisms of persistent and treatment resistant manifestations of LB that may lead to longstanding disability of the patients.
First hypothesis is that borrelia interferes with dendritic cells (DCs) that are important operators in the initiation and regulation of immune response. Second hypothesis is that borrelia infection becomes latent during antibiotic treatment and borrelia resides in a dormant form in host tissues.