Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.

Form Supplied

Liquid

Concentration

85
mg/ml
(Please refer to the vial label for the specific concentration)

Purification

Antiserum

Purification Note

Sterile filtered

Specifications: CDK5 antibody

Full Name

cyclin-dependent kinase 5

Product Description

Rabbit Polyclonal antibody to CDK5

Background

The protein encoded by the gene CDK5 is involved in the control of the cell cycle and interacts with D1 and D3-type G1 cyclins. CDK5 belongs to the protein kinase superfamily, the CMGC Ser/Thr protein kinase family and the CDC2/CDKX subfamily. CDK5 phosphorylates histone H1, tau, MAP2 and NF-H and NF-M and also interacts with p35 which activates the kinase. CDK5 forms a heterodimer, where CDK5 is the catalytic subunit and p35 is the regulatory subunit. CDK5 is also found in a trimolecular complex with CABLES1 and ABL1. CDK5 is a cytoplasmic protein.