Running backs Dalvin Cook and Leonard Fournette have been sidelined for good portions of the start of the season; tight ends Evan Engram and Greg Olsen are close to returning; and wide receivers T.Y. Hilton, Randall Cobb, and Geronimo Allison are all dealing with nagging injuries that that will likely leave them questionable for Week 6. As always, there are a lot of injuries around the league that are affecting fantasy football rankings, strategy, and start 'em, sit 'em calls, and Week 6 will be no different.

Dalvin Cook injury update

Cook's hamstring kept him out of Week 5, and it seems possible that he will miss Week 6. He didn't practice all of last week, and NFL Network's Ian Rapoport reported that he would have needed an "impressive turnaround" to play last week. That said, considering that Cook will have had 17 days between games by Sunday, there's at least a chance he could suit up for the upcoming week, but he would need to see an upgrade in practice status this week for sure.

If Cook is out again, the Vikings would rely on Latavius Murray to carry the load. That hasn't necessarily been a winning proposition in recent weeks, but against the weak Cardinals defense, Murray should have a chance to punch in a TD and rack up some yardage. Of course, if Murray struggles, it will give Kirk Cousins and the passing game a boost for yet another week.

Leonard Fournette injury news

After Fournette suffered a setback with the hamstring that has been plaguing him all year, it was assumed that he would be out for at least a couple of weeks. And that appears to be the case.

According to NFL Network's Ian Rapoport, Fournette is going to miss the Jaguars Week 6 battle with the Cowboys as he continues to deal with the injury. This declaration came very early in the week, but again, given the multiple-week timeline on the injury plus the nature of lingering hamstring injuries, this is hardly a surprise.

With Fournette out, T.J. Yeldon will continue to operate as the lead back in Jacksonville. He can be used as a starter, as reflected in our Week 6 RB rankings (even higher in the PPR RB rankings), and it's worth noting that his only backup is Brandon Wilds now that Corey Grant has been placed on IR. That said, the Jaguars are working out some other RBs -- including veteran Jamaal Charles -- so it's likely that they will have a new man on the roster at some point soon. Still, Yeldon is the man to own in that backfield without a doubt.

Is Evan Engram playing Thursday night?

UPDATE: The Post's Paul Schwartz is reporting that Shurmur has said Engram will be out at "full speed" in Tuesday's practice. That's obviously a positive development for him and his potential availability for Thursday.

With Engram being on a short week, many assumed that it would be difficult for him to suit up after suffering an MCL sprain in Week 3 against the Texans. However, SNY's Ralph Vacchiano is reporting that Giants head coach Pat Shurmur said that Engram has "a shot" to play this week. If he can get on the field, that would be huge for the Giants, as it would give them another weapon in the passing game.

It seems that Engram is heading for a truly "questionable" tag ahead of Week 6 against the Eagles. Thankfully, he's playing on Thursday night, so we'll know his status well ahead of time. That said, if he's on the field, fantasy owners will have to start him given how thin the TE position is. Currently, Engram isn't included in our TE rankings, but rest assured that he will be added to the top 10 if he ends up playing.

T.Y. Hilton injury update

Hilton missed Week 5's matchup with the Patriots after suffering a hamstring injury the previous week. With 10 days to recover ahead of Week 6, there's a chance that Hilton could be on the field, but since hamstring injuries tend to linger, it will be extremely important to watch his practice status this week.

If Hilton is out for another week, Chester Rogers will probably be the No. 1 receiver. Rodgers has logged eight catches in each of the past two games and put up at least 66 yards as well. Eric Ebron would also get a bump to his stock at the TE position. For now though, not much is known about Hilton's status, so check back often and we'll keep you posted.

Randall Cobb, Geronimo Allison injury news

Cobb has missed the last two weeks with a hamstring injury, but with another full week to recover, there's a chance that he could be ready to play in Week 6. The Packers have a Monday-night meeting with the 49ers, so that will buy Cobb some extra time to get fully healthy. After not practicing last week, his practice status will be key to watch -- especially for fantasy owners worried about his late-week matchup.

As for Allison, he missed last week's outing with a concussion, but ESPN's Rob Demovsky had previously reported that there was "hope" that Allison would practice last Saturday before the Packers game. However, that didn't end up happening and he did sit out the game. Still, it's positive that there was even hope that he would be on the practice field, and with another week to get out of concussion protocol, Allison should have a chance to suit up on Monday.

In the event that either Cobb or Allison can't get on the field, Marquez Valdes-Scantling would continue to see action. The rookie looked solid last week and should be able to put up a good game even as the third or fourth option against a weaker 49ers secondary.

Is Greg Olsen playing in Week 6?

Olsen (foot) continues to say he expects to return in Week 6, but it's worth noting that he'll need surgery at the end of the season, so clearly he's still "playing hurt."

Given his talent and big role in the Panthers' offense, Olsen should be considered a borderline TE1 when he's on the field, but he's not a "must-start" given the questions surrounding his health.