The 29-year-old was substituted off at half time of the DFB-Pokal clash against Werder Bremen last Tuesday with a muscle injury, and did not feature in their 3-3 draw against Hoffenheim in the Bundesliga.

Reus has struggled with injuries in the recent past, but has enjoyed this season for Dortmund, which has seen them occupy top spot in the Bundesliga and are 5 points clear of rivals Bayern Munich.

Zorc did not confirm Reus’ miss for the game at Wembley, but remains pessimistic about his chances of making the squad.

While speaking to Ruhrnachrichten, Zorc said, “I think we will decide that in the short term, but I do not expect a miraculous recovery before Wednesday.”

Borussia Dortmund’s Marco Reus

While Dortmund will miss Reus on their trip to Wembley, Tottenham have been struggling with injury problems of their own, Harry Kane being the biggest miss. The England and Tottenham star injured himself last month during their loss to a resurgent Manchester United team, and was expected to be out till March, but Kane has made good progress, and might return early, however Spurs manager Mauricio Pochettino confirmed Kane will not be able to play against Borussia Dortmund.

Pochettino said on Friday, “Now he is here, he is doing well, he is doing fantastic. We need to stop him every day because he wants to be ahead of his recovery and he’s very optimistic and determined to play as soon as possible. He’s so close to come back again. Not for Sunday, not for Wednesday but we will see after.”

Spurs are also without another England star, Dele Alli who also got injured in January, and will be out till March, Pochettino confirmed.

“It’s a different injury [to Kane’s] and I think we need to look at it in a different way,” Pochettino said. “He is doing well and we are happy with the way that he is recovering.”