In a study focused on a group of former professional athletes who have experienced multiple concussions, over half the group were reported to have higher levels of tau protein biomarkers in their cerebrospinal fluid.

The Medical Research Council (MRC; London, UK) has determined the atomic structures of abnormal tau filaments related to chronic traumatic encephalopathy (CTE) and discovered that the structure is different to tau filaments seen in Alzheimer’s disease.