In Vizunah Square, a party of characters from outside Cantha accompanied by Mhenlo meet with a party of Canthan native characters with Master Togo. Together the parties fight through droves of afflicted to find the source of the plague in Kaineng City.

Typically, the Canthan party starts from the Vizunah Square (Local Quarter) outpost, while the Prophecies and/or Nightfall party starts from Vizunah Square (Foreign Quarter) outpost, although this can vary. Although these show up as separate locations on the map, with their own mission symbols, they both refer to the same mission.

Locate the source of the plague in Kaineng City.
Find Togo in Vizunah Square. (If your party is from Vizunah Square (Foreign Quarter).)
Hold out until Mhenlo 's party arrives. (If your party is from Vizunah Square (Local Quarter).)
Travel with Mhenlo and Togo in search of the plague's source.
Defeat Shiro's Construct.

The local and foreign parties start at separate locations. The local party, together with Master Togo, will enter an area where they will be faced with spawning Afflicted. The foreign party, with Mhenlo, will need to fight several groups of Am Fah enemies first to make their way to the meet up point, unless the foreign group is completely computer controlled, in which case they do not need to fight anyone before the parties merge. Since Master Togo has to be kept alive, a common reason to fail the mission is for the local party to become overwhelmed and Togo dies, before the foreign party arrives. To prevent this, the local party should place more emphasis on healing compared to the foreign one. Once the two groups meet, healers from both parties are able to heal both NPCs.

After the first large battle, the mission follows a linear path, including two other large fights at Afflicted spawning points. During these fights, multiple waves of Afflicted spawn (and respawn) from three separate points. The Afflicted Soul Explosion can overwhelm parties in these situations. Eliminating the afflicted bosses will stop the respawning of Afflicted and cause the opening of the nearby gate, allowing continuation of the mission. Spread apart and try to intercept the spawns with three "mini-parties" instead of fighting them all in one big melee.

Note that while you can heal members of the other group, you cannot resurrect them. Each party has to provide for their own means of resurrection.

This mission has numerous bugs, some forcing a restart. See the notes for details.

Master Togo:"This district has been overrun with the plague while others have been spared. Let us find out why."

Brother Mhenlo:"I am certain that this is no natural affliction. It corrupts not only the body but also the soul."

Master Togo:"I agree that the cause of the plague is something supernatural...and I believe we will find it in this district."

After leaving the first choke point.

Canthan Guard:"Leave the city or fend for yourself. We cannot protect you within the city walls."

When a group of Am Fah spawn.

Brother Mhenlo:"Am Fah! No doubt these scoundrels are trying to capitalize on the chaos the plague is causing."

Master Togo:"I doubt they are responsible for the plague, but I'm not surprised to find them in its midst. The city guards are too busy to keep them at bay."

After the final afflicted group is defeated at the second choke point.

Master Togo:"We suffered an outbreak of this same disease back on Shing Jea Island. The corruption emanated from a temple that bore the mark of Shiro Tagachi."

Master Togo:"But it has been two hundred years since Shiro killed the emperor he was sworn to protect. Why would his curse take so long to manifest?"

Brother Mhenlo:"It might not be a curse. There are tales of evil spirits causing physical corruption. If Shiro's spirit has returned somehow, it could cause a plague. We should search for signs of him."

After the final afflicted group is defeated at the third choke point.

Master Togo:"There was great evil here...I can feel it. I think you are right, Mhenlo. The very spirit of Shiro Tagachi has returned. But why here?"

Brother Mhenlo:"I remember this bookstore, Master. It held magic and religious text from across the world."

Master Togo:"I thought our temple was defaced because it was a holy place, but it too was a center of learning... Shiro must be looking for something. We must find him before he finds it."

When reaching a closed, guarded gate.

Master Togo:"In the name of the emperor, open this gate!"

Canthan Guard:"You will find nothing but trouble this way. With all the chaos, the Am Fah are running things down here."

When a boss is killed, the subsequent Morale Boost is only awarded to the party that inflicted the killing blow.

You will have to fight some of the Canthan civilians, who have been infected by the plague. On dying, they will spawn an Afflicted creature; such spawned Afflicted, while technically hostile to the party, will not attack you and will generally try to flee. However, you'll usually end up killing them anyway as any NPCs in your party will attack them.

The death that occurs during the end cinematic does not halt progress of the Survivor title track.

A large chunk of the inaccessible southeast corner can be explored for Canthan Cartographer by viewing the mission cinematic. (Talk to Guardsman Chow in the Foreign Quarter to replay it.)

Bug.This mission highlights many deficiencies in the NPC pathfinding AI:

It is possible for a henchman-only party to get stuck behind a chest, forcing you to either restart the mission or continue alone. If the henchman party is starting from the Foreign Quarter, this can happen before they reach the first meeting point. It is possible for Togo or Mhenlo to get stuck in the same way.

It is possible for Togo to just get stuck for no reason, which causes the last fight to fail to initialize, making the final battle of the mission impossible to complete.

If you bring minions, Mhenlo can get distracted in healing them, causing him not to reach his waypoints. A sign that this has happened is Togo standing still some distance behind the party. If this happens, try moving back towards Togo; when Mhenlo gets close enough, the missed waypoint will trigger and Togo will start moving again.

Anomaly. If your party has a monk maintaining Unyielding Aura, Shiro won't wipe the whole party. If the party leader is resurrected by this means, he/she will not appear in the proper place for the cinematics.