depends what's in the LS-2 as to how it will act with a comp in front, only way to truly know is to experiment.
I use a BDDI and two LS-2's in my rig, the BDDI has never caused me issues no matter where I place it.
only certain fuzz pedals seem sensitive to having buffers in front of them,

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depends what's in the LS-2 as to how it will act with a comp in front, only way to truly know is to experiment.
I use a BDDI and two LS-2's in my rig, the BDDI has never caused me issues no matter where I place it.
only certain fuzz pedals seem sensitive to having buffers in front of them,

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I have a Synth and octave pedal after the compressor.

Which helps it track better, So do i place the compressor synth and octave in loop A of the Ls-2 as i planned to put just the Fuzz ,Chorus and Delay in Loop A and use A+B mix for a Dry signal with them.

Which helps it track better, So do i place the compressor synth and octave in loop A of the Ls-2 as i planned to put just the Fuzz ,Chorus and Delay in Loop A and use A+B mix for a Dry signal with them.

Also any idea how the FX send and return of the BDDI works

can i save an effect in the presets?

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I wouldn't put the fuzz in a loop because fuzz pedals usually don't like buffers. I'd go fuzz, compressor, LS-2....

I've never seen a BDDI with an effects loop or presets, are you sure it's a BDDI?

The FX loop can be stored in any preset or you can use it manually. It will retain the last setting used however. For instance, if you have the loop programmed into say preset 1 and turn off the fx loop while in that preset, the next time you engage that preset the efx loop will be off. You would have to re-engage the FX loop before you changed presets or turned off the preset to keep the same setting.