Even the biggest cities of the Revolutionary War era America sadly looked like crap compared to the beautiful cities of Europe, based on that the setting doesn't seem like a good idea.

Was just about to say that. At this time surely the US wouldn't have any major landmarks like the Mosques and cathedrals of the other games, and the cities themselves at this time wouldn't have been on the scale or very architecturally inspired.

I may be wrong, as in all honesty I don't know a lot about the US, but my initial impression of this time period for the US is it was still not built up that much and the large cities were only just becoming that.

Rodrigo
Main article: Pope Alexander VI
Rodrigo Borgia (1431 – 1503), one of Alfons’s nephews, was born in Xàtiva, also in the Kingdom of Valencia. While a cardinal, he maintained an illicit relationship with Vanozza dei Cattanei from the House of Candia, and they had four children: Cesare, Giovanni, Lucrezia and Gioffre. He also had children by women other than Vannozza; Giulia Farnese was among his other mistresses. He was raised to the papal chair in 1492 and he chose the name of Alexander VI.
He was considered a good politician and diplomat, but he was also criticized for over-spending, simony and nepotism. His main interests lay in acquiring more wealth, seducing women, and making his family as powerful as possible. He planned to establish an empire with the assistance of his second oldest son, Giovanni, who was appointed captain-general of the papal army. Rodrigo had also honored his eldest son, Cesare, by nominating him cardinal when he was 18.
Alexander organized alliances through the marriages of his children. The Sforza family, which comprised the Milanese faction, was at the time one of the most powerful in Europe. Alexander married Lucrezia to Giovanni Sforza; in so doing, he united the Borgia and Sforza families. He also found another way of establishing his position – he married his youngest son from Vannozza, Gioffre, to Sancia of Aragon of the Kingdom of Aragon and Naples.
Rodrigo Borgia was said to have died in 1503 in Rome from a poisoned apple, but the actual cause of death was malarial fever. His pontificate is frequently characterized in extremities – he is often said to have been the worst of all Popes. The era in which Alexander VI held supreme papal power was full of scandals, infringements and signs of moral offense among the highest authorities of the Latin Church.

This is why they chose Rodrigo Borgia to fuck with. (he wasn't a good guy).

So we cant pick a president of a country which helt black and chinese slaves and murdered native americans?

Did any presidents of the period die untimely or unnatural deaths? Were they murdered?

The period shown is the 18th century, not the 19th century.

Also lets not delve into ALL THE SHIT EVERY OTHER NATION HAS DONE TO EACH OTHER. I mean if you really want to pick on countries for the shit they've done, take a look at European imperialism in the late 19th and early 20th centuries.