Children up to 18 years of age-Use is not recommended in infants, children, or adolescents since fluoroquinolones cause arthropathy in immature animals .
However, ciprofloxacin has been given to pediatric patients, as indicated below, when alternative therapy could not be used. Based on pharmacokinetic studies, dosing for patients with cystic fibrosis should be higher and at more frequent intervals than for patients without cystic fibrosis .
Dosing for cystic fibrosis patients also should be decreased as body weight increases .
Anthrax, inhalational (treatment) -
Oral, 15 mg per kg of body weight per dose (base), not to exceed 500 mg per dose, every 12 hours for 60 days.
[Cystic fibrosis, pulmonary exacerbations] -
For children 14 to 28 kg of body weight: Oral, 28 to 20 mg (base) per kg of body weight every twelve hours, up to 2 grams per day .
For children 28 to 42 kg of body weight: Oral, 20 to 15 mg (base) per kg of body weight every twelve hours, up to 2 grams per day .
[For other infections] -
Oral, 10 to 15 mg (base) per kg of body weight twice a day, up to 1.5 grams per day .