..Most of the published panic/HPA literature is consistent with the hypothesis that HPA axis dysregulation in panic is due to hypersensitivity to contextual cues. This hypothesis requires experimental testing...

..However, basal levels of GH release over a full circadian cycle have not been examined in panic. Reduced basal GH release would suggest an overall hypo-active GH system rather than a specific alpha-adrenergic abnormality...

Respiratory psychophysiology and anxiety: cognitive intervention in the doxapram model of panic

..Cortisol responses to laboratory stressors predict consumption but it is unclear whether such responses mark a vulnerability to stress-related eating or whether cortisol directly stimulates eating in humans...

Effect of repeat exposure on neuroendocrine and symptom responses to pentagastrin

..g. anterior cingulate cortex, "ACC") might play a role. In this study, we explored the hypothesis that trait anxiety would be associated with ACC activity in an attentional control task with varying levels of threat interference...

Impact of social anxiety disorder on employment among women receiving welfare benefits

..The findings support the hypothesis that the rostral extent of the MFC (rACC) processes loss-related responses to errors, and individual differences may account for some of the reported variation of error-related foci in the MFC...

The buffering effects of active coping on the relationship between SES and cortisol among African American young adults

Karen H Schmeelk-ConeUniversity of Michigan School of Public Health, USABehav Med 29:85-94. 2003

..The authors suggest that coping style may play an adaptive role regarding salivary cortisol measures in young adults when they are students or unemployed. Active coping may help protect against stress among young African American adults...

Research Grants1

..Existing animal data will be used to identify factors within the cognitive intervention which likely account for its potency and dismantling studies will be done to examine the separable effects of these factors. ..