2 - late deaths (1 died after Glenn due to hypoxia and low cardiac output and 1 died at Fontan from ventricular dysfunction).

2 - lost to f-up.

2) TV repair (n=4)

3 hospital deaths, 1 survivor is doing well at 12.5 yrs.

3) TV closure (n=11)

3 hospital deaths.

1 late death at 3 months (sudden death; unknown cause)

Remaining 7 had Fontan.

Overall survival:

All neonatal surgeries:

66.7% at 1 yr

62.2% at 5, 10 yrs

51.9% at 15 yrs

TV closure:

63.6% at 1, 5, 10 yrs

47.7% at 15 yrs

Shunt only:

88.9% at 1 yr

76.2% at 5, 10 yrs

TV repair:

25% at 1, 5, 10, yrs.

Comments: Review article. Not randomized. No clear indication as to equal disease severity of Ebsteins who underwent different interventions. Therefore, this should not be viewed as comparison of surgeries for the same severity of disease. Each patient would have been evaluated and the surgical option applied depending on disease features and institutional experience.

10/08/2009

Erythromycin is used as a prokinetic for GI mobility. This is used in some postoperative cardiac patients when Metoclopromide is deemed to be not useful. What is the effect of Erythromycin on the heart? Why is it risky to use?