Rodney Hood scored 21 points to help the sixth-ranked Blue Devils beat Virginia Tech 66-48 on Tuesday night, a game that followed a demanding stretch that included games against their fiercest rival and the nation's top-ranked team in a span of about 48 hours.

Duke (23-6, 12-4 Atlantic Coast Conference) completed a stretch of five games in 11 days by beating the last-place Hokies (9-18, 2-13).

The Blue Devils fought to the final second to hold off Maryland on Feb. 15, then traveled to Georgia Tech before losing the weather-delayed rivalry game at North Carolina. Two nights later, they held off then-No. 1 Syracuse at home, then returned once more to Cameron Indoor Stadium to beat Virginia Tech in what Krzyzewski called "a grueling stretch."

"It's kind of like -- I don't know if you do this -- getting that last bit out," Krzyzewski said. "Even though you've got two full containers, you're going to get that last little bit. Today was kind of, let's get it out there."

Duke doesn't play again until next Wednesday's trip to Wake Forest, followed by the regular-season finale against UNC at Cameron Indoor Stadium on March 8. The Blue Devils have won 32 straight home games, the longest streak in the nation.

"Probably everybody in the back of their minds was looking forward to (the break)," sophomore Rasheed Sulaimon said, "but at the same time we knew we had to take care of business."

Hood said the coaches didn't let the players ease into this one, jumping on them about a sluggish pregame shootaround. The Blue Devils responded by running out to a 24-4 lead midway through the first half, though they struggled to land a game-finishing blow on the Hokies.

"We started to warm up and we came back in and they got us pretty good because we didn't look like we were ready to go out there and fight," Hood said. "I mean, we've got to be prepared for that. The ACC tournament, you can play three or four games in three or four days so there's no excuse for us. I think it's taxing on us, but we've got to be ready and get rejuvenated for next week."

The win, along with Clemson's loss at Wake Forest, helped secure some extra rest for the Blue Devils. They are assured a top-four seed in Greensboro and the double-round bye that comes with it.

Sulaimon scored 15 points for the Blue Devils, who shot 39 percent and went 10-for-33 from 3-point range -- well below their ACC-leading 40.7 percent from behind the arc.

Freshman Trevor Thompson matched his season-high with 15 points for Virginia Tech, which has won once since the start of the calendar year. The Hokies have failed to reach 60 points in 10 of those 14 games.

Virginia Tech finished with 15 turnovers, six from freshman Devin Wilson, that led to 22 points for the Blue Devils. The Hokies also went 8 minutes without a basket in the second half as Duke crept further ahead.

"They do what bothers us, that pressure defense bothers us," Hokies coach James Johnson said. "And they did a good job with that. And at that time (in the second half), we're probably running out of gas a little bit."

Duke ran out to a 15-2 lead on Sulaimon's first 3-pointer, then pushed the early lead to 20 points when Sulaimon knocked down another 3 off a feed from Hood at the 9:50 mark.

Virginia Tech cut into the deficit when reserve C.J. Barksdale came in and hit shots on three straight possessions to finally give the Hokies some confidence. Then, after trailing 32-20 at halftime, Jarell Eddie drove by Hood for a basket that got the Hokies within 34-27 with 17:59 left.

But Virginia Tech got no closer, with Sulaimon knocking down two 3s then reserve big man Marshall Plumlee slamming home a miss to push the lead to 51-36. The Hokies never got the lead to single digits again.