MSF-USA was founded in 1990 in New York City to raise funds, create awareness, recruit field staff, and advocate with the United Nations and US government on humanitarian concerns.

In 2012, MSF-USA raised $189.3 million, representing more than 20 percent of the MSF network’s private funding. In 2012, it sent 376 US-based aid workers on assignments overseas, liaised with a wide range of US media, organized high-level meetings with UN and US government officials, and arranged regular speaking events and activities across the US.