PSYC430 Synaptic Plasticity Mechanisms

Animals must learn to survive, and the brain is the learning machine that does
the job. But how does it do it? In this paper, we investigate the neural mechanisms
of learning and memory, with particular emphasis on the physiological, molecular and
anatomical mechanisms of synaptic plasticity in the hippocampus and related brain
regions. We take a critical look at the evidence regarding the mechanisms underlying
Long-term potentiation, and long-term depression, and whether they have the behavioural
relevance that is commonly assumed.

Entry into Psychology 400-level normally requires a major in Psychology, a B+ average
or higher in Psychology 300-level papers, and a pass in PSYC 311 Quantitative Methods.
We highly recommend that students have completed PSYC 310 and PSYC 317 or equivalent.
Students from other universities must show evidence of an equivalent level of competence.

For
Neuroscience students, the prerequisites are met by completion of the requirements
for a BSc in Neuroscience with an average grade of at least B+ in 300-level Neuroscience
papers.

Timetable

First Semester

Lecture

Stream

Days

Times

Weeks

Attend

A1

Wednesday

09:00-11:50

9-16, 18-22

Exploration of synaptic mechanisms of memory formation.

Animals must learn to survive, and the brain is the learning machine that does
the job. But how does it do it? In this paper, we investigate the neural mechanisms
of learning and memory, with particular emphasis on the physiological, molecular and
anatomical mechanisms of synaptic plasticity in the hippocampus and related brain
regions. We take a critical look at the evidence regarding the mechanisms underlying
Long-term potentiation, and long-term depression, and whether they have the behavioural
relevance that is commonly assumed.

Entry into Psychology 400-level normally requires a major in Psychology, a B+ average
or higher in Psychology 300-level papers, and a pass in PSYC 311 Quantitative Methods.
We highly recommend that students have completed PSYC 310 and PSYC 317 or equivalent.
Students from other universities must show evidence of an equivalent level of competence.

For
Neuroscience students, the prerequisites are met by completion of the requirements
for a BSc in Neuroscience with an average grade of at least B+ in 300-level Neuroscience
papers.