Jenny Meadows's participation in the London 2012 Olympics is in doubt after she was ruled out of this weekend's trials in Birmingham. The 800m runner has not raced at all this year because of an achilles injury.

Meadows is still recovering from the problem and will now need to rely on the discretion of the selectors to be awarded the third and final place on the team for London. "I am gutted to be missing out on the trials, but we always knew it would be a race against time to be fit enough," she said. "Every day of my recovery is like a week so the extra few days ahead of [the European championships in] Helsinki will make a big difference to the injury and ensure I am able to go out and compete and demonstrate my fitness ahead of selection for London 2012."

Jeanette Kwakye, a 2008 Olympic finalist in the 100m, will also miss the trials due to an achilles and ankle injury. "I have been working with the UKA medical team at Lee Valley and on their advice and in consultation with my coach Michael Afilaka we have decided to miss the trials," said Kwakye, who has a best of 11.68sec this year and sits well down the British rankings. "We will reassess the injury on Monday in relation to the European championships.

"I am eligible for selection for the Games and am still determined to be fit and ready for competing in my own backyard in Stratford."

The pair's withdrawal is worrying news with the Games six weeks away and comes just a day after Hannah England, the world championships silver medallist over 1500m, announced she too would miss the trials after suffering a spike to her achilles in a race in Holland three weeks ago.