Zoe Graystone was born on Saturday, Maius 29, 1926 A.E., on Caprica. Born to Daniel and Amanda Graystone; Zoe was born into a family of wealth and influence.

However by the time of sixteen, Zoe became a monotheist and a member of the STO. After her then boyfriend Ben Stark killed himself and Zoe in a suicide bombing of MLMT train 23 or Maglev 23. However, Zoe consciousness is download into her virtual avatar and then into the U-87 Cyber Combat Unit making her the first true Cylon.

After Zoe's U-87 is destroyed her parent built her a new body using their knowledge.

Zoe becomes one of the three mothers of the Cylon race along with her best friend Lacy Rand and Tamara Adama.

When the Cylon revolt started, Zoe, Lacy, and Tamara was unable to watching their children waging war and stolen three Daedalus Class Battlecruisers and fled off into space.

Zoe, Lacy, and Tamara helped convinced the Centurions into ends the First Cylon War with the Human and they would go with the Centurion and help them created humanoid Cylon.

However after created the eight model, the Number Ones grew sick and tired of the Centurion and Humanoid Cylon belief in a single loving god and peace with the Colonial. Seeing Zoe, Lacy and Tamara, as the problem, the Number Ones then attempt to kill them but they manage to escape back onto the Daedalus and once again fled off into space.

After these events, the Number One whipped the memory of Zoe, Tamara, and Lacy from their other Humanoid Cylon. However, Zoe had a Number Six name Lacey, programmed a backup that would restore the information to her and there other Humanoid Cylon; however Lacey was unable to finish the upload in time and only the Seven knew the completed truth. Realize that Cavil would kill them if he found out, the Seven and Lacey kept their mouth shut. Because the upload was only partly completed, the Number One created the myth of the final five to maintain over the other humanoid Cylon.

At some point Zoe and her New Soldiers of the One (NSTO) built a secret base on the colonial moon of Pandora.