LaBarbera's first full season in the NHL was spent backing-up Kings starting goaltender Mathieu Garon. He got off to a quick start with the Kings, going undefeated in his first seven starts. LaBarbera earned his first career NHL shutout on April 17, 2006, blanking the San Jose Sharks in a 4–0 victory.[5]

LaBarbera with the Canucks in 2009.

In 2006–07, LaBarbera played for the Kings' minor league affiliate, the Manchester Monarchs, in the AHL. Despite injuries to Kings goaltenders Mathieu Garon and Dan Cloutier during the season, the Kings were hesitant to recall LaBarbera because he was waiver eligible, which required him to clear waivers in order to be recalled and demoted, making it likely that he would be claimed by another team. LaBarbara completed the season with the Monarchs and earned the second Harry Holmes Memorial Award and Aldege Bastien Memorial Award of his AHL career. In the off-season, LaBarbera re-signed with the Kings to a two-year contract on July 3, 2007.[6]

LaBarbera earned more playing time in 2007–08, appearing in a career-high 45 games with a 3.00 GAA and a .910 save percentage. The following season, on December 30, 2008, LaBarbera was traded to his hometown team, the Vancouver Canucks, in exchange for a seventh-round draft pick in 2009. The Canucks dealt for LaBarbera in light of injuries to Roberto Luongo and backup Curtis Sanford.[7] LaBarbara earned his first win with the Canucks in his club debut, making 31 saves in a 2–1 victory over the Nashville Predators on January 1, 2009.[8]

LaBarbera was signed to a two-year, $2 million contract by the Phoenix Coyotes to back-up Coyotes starter Ilya Bryzgalov on July 1, 2009.[9] LaBarbara compiled a total record of 15–11–4 in his first two seasons in Phoenix. On June 6, 2011, he was re-signed by the Coyotes to another two-year contract.

On July 5, 2013, during the free agency period of 2013, LaBarbera signed a one-year, $1 million deal with the Edmonton Oilers.[10] He competed with Richard Bachman to be the backup to starter Devan Dubnyk. After Bachman was injured, then sent down to Edmonton's AHL affiliate, LaBarbera won the backup job in Edmonton.

On December 14, 2013, LaBarbera was traded to the Chicago Blackhawks in exchange for future considerations.[11]

On July 1, 2014, the Anaheim Ducks signed LaBarbera as a free agent to a one-year, $750,000 contract.[12] He attended the Ducks' training camp before ultimately being assigned to their AHL affiliate, the Norfolk Admirals, after clearing waivers.

LaBarbera and his wife Kodette are the parents of two sons. Their son Ryder was diagnosed with autism. Kodette stars in the Canadian W Network TV show Hockey Wives and talks about her son's autism treatment program in Calgary, Alberta.[13]