I picked up some Spike tabs on clearance a while back and liked them,no fever like symptoms etc.

I just looked into fursultiamine and the same potential issue (neurotoxicity) is applicable to it.I came across a positive abstract for thiamine supplementation though,while another abstact (which I posted above) showed no signifigantly positive effects WRT sulbutiamine.I'm not all that convinced fursultiamine is worth sourcing either.

Thiamine's bioavailability is much less than its analogues so a decent dose should be all that's needed.If you wind up in an ER though,I'd ask for some fursultiamine.

I use more stims than I should,in conjunction with bezafibrate (which are primarily oxidized in the heart) if I overeat and DNP while dieting.I am satisfied with a heart protective stack of COq10,hawthorn berry and fish oil along with thiamine.I do like AMPV.2 (with fursultiamine) but no longer think that fursultiamine is a staple for tweakers.But it woul;dn;t hurt to have some on hand in case of an intense heart pain flareup.

High-dose thiamine (vitamin B1) supplementation (100 mg/day) may be helpful in preventing or accelerating recovery from exercise-induced fatigue. Sixteen volunteer male athletes volunteer, 8 with a blood thiamine level of 40 ng/ml or more (normal thiamine group) and 8 with levels below that level (low thiamine group) were selected as subjects. They exercised on a bicycle ergometer and the effects of thiamine supplementation were compared with placebo. Blood thiamine level markedly increased following supplementation of thiamine for 3 days before exercise. Exercise-induced changes in hemodynamic parameters and cardiopulmonary function indicated the onset of fatigue. Thiamine supplementation significantly suppressed the increase in blood glucose in the normal thiamine group and significantly decreased the number of complaints shortly after exercise in the subjective fatigue assessment of 30 items.

Neither study comes to much of a conclusion though so if you are a heavy stim user with extra money and suspect or know that you have a history of family heart trouble,fursultiamine would be a good play.

Neither study comes to much of a conclusion though so if you are a heavy stim user with extra money and suspect or know that you have a history of family heart trouble,fursultiamine would be a good play.

That's me and thanks for the bottom line, Colin.

ATM i have a bag of NP's Sulbutiamine caps i must use up first so by then there may be some headway on a pure fursultiamine supp.