Description:
Alarin is a hypothalamic neuropeptide which binds to the G-protein-coupled galanin receptors (GALR1, GALR2, and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin-releasing hormone secretion. Isoform 2 exhibits potent and dose-dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, a physiologic effects which does not appear to be mediated via GALR1 or GALR2 (By similarity). Cleavage of the signal peptide generates a peptide of 25 amino acids, termed alarin because of the N-terminal alanine and the C-terminal serine. Involved in ganglionic differentiation in neuroblastic tumor tissues.

Applications:Suitable for use in Immunofluorescence and Immunohistochemistry. Other applications not tested.

Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Type

Isotype

Clone

Grade

Pab

IgG

Serum

Size

Storage

Shipping

Source

Host

100ul

-20°C

Blue Ice

Rat

Rabbit

Concentration:

Not determined

Immunogen:

Synthetic peptide corresponding to rat Alarin.

Purity:

Serum

Form

Supplied as a lyophilized powder. Reconstitute with 100ul sterile dH2O.

Specificity:

Recognizes rat Alarin. Species crossreactivity: mouse.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.