Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects,
reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Grapefruit juice can cause the level of Colchicine in your blood to get too high. Talk with your health care provider before you take these medicines together. If you have kidney or liver disease, you may need less medicine. Call your doctor right away if you take these medicines together and you have any of the following: dark urine; bloody, black, or tarry stools; new or unusual bruises; unusual bleeding; nausea, vomiting, diarrhea or stomach cramping; numbness, tingling or pain in your hands or feet; pain or burning in your stomach or throat; or urinating less often.

Avoid alcohol-containing drinks while taking Colchicine. Gastrointestinal side effects from Colchicine may get worse and the actions of Colchicine may decrease if you drink alcohol-containing drinks while taking Colchicine. You may also have increased effects from alcohol including dangerous effects on breathing.

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.