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Our goals are to provide Indian-origin SPF rhesus monkeys for biomedical research, particularly for AIDS-related research, to acquire and provide non-rhesus macaques to programs using other macaque species not bred at SNPRC and to manage the research projects that are conducted with macaques at SNPRC.

SNPRC fulfills a critical need by producing high-quality SPF Indian-origin rhesus macaques for the national AIDS-related research effort using state-of-the-art viral testing methods. We provide pedigreed monkeys with known genetic relationships from two genetically diverse colonies. One is a Specific-Pathogen-Free (SPF) rhesus monkey breeding colony, which produces monkeys for national AIDS-related research. The other produces monkeys with Familial Hypercholesterolemia, which are highly useful for research on mechanisms and corrective therapies for this condition.

We also provide monkeys that are typed for MHC class I and genetically manage the colonies. More than 900 rhesus macaques have been genotyped. We have developed a cost-effective plan for genetic management and characterization of NHP breeding colonies using high throughput sequencing methods. Our total genome sequence data maximizes diversity and retains important allelic variants.

Finally, we procure macaques of any species not available within the SNPRC for investigators who request them, and manage the experimental protocols to which animals of any macaque species are assigned.