Overview

Dr. Stone directs the Autopsy Service and Cardiovascular Surgical Pathology Service at Mass General. He is head of the Cardiovascular Histology Core Facility, a core laboratory for NIH-funded multicenter trials relating to cardiovascular diseases.

Biography

Dr. Stone has published extensively on cardiovascular diseases including atherosclerosis, vasculitis, amyloidosis, and cardiomyopathies. He is a founding co-chair of the Standards and Definitions Committee of the Society for Cardiovascular Pathology, and directs the core laboratory of an NIH-funded multi-center study of cardiac allograft rejection. He is a member of the Center for Systems Biology, where his laboratory studies basic mechanisms relating to the cellular and molecular biology of cardiovascular diseases

Research & Publications

My lab focuses on elucidating the mechanisms of cardiac and vascular diseases. We are working to understand the biochemical processes resulting in atherosclerosis. Investigations are focused on signal transduction mechanisms responsible for the pre-atherosclerotic intimal hyperplasia, and the factors stimulating the formation of intimal necrotic/lipid cores. For more details, visit the Stone Lab. For information about research concepts, co-authors, and to see a timeline, visit Dr. Stone's profile at the Harvard Clinical and Translational Science Center.