Houston Texans defensive end Jadeveon Clowney (90) stops Oakland Raiders fullback Jamize Olawale (49) during the second quarter of an NFL football game at Estadio Azteca on Monday, Nov. 21, 2016, in Mexico ... more

Photo: Brett Coomer, Staff

Image 2 of 7

Houston Texans' Jadeveon Clowney is shown during the first half of an NFL football game Sunday, Nov. 27, 2016, in Houston. (AP Photo/David J. Phillip)

Houston Texans' Jadeveon Clowney is shown during the first half of an NFL football game Sunday, Nov. 27, 2016, in Houston. (AP Photo/David J. Phillip)

Photo: David J. Phillip, Associated Press

Image 3 of 7

Houston Texans defensive end Jadeveon Clowney (90) wraps up Oakland Raiders fullback Jamize Olawale (49) during the second quarter of an NFL football game at Estadio Azteca on Monday, Nov. 21, 2016, in Mexico City. ( Brett Coomer / Houston Chronicle ) less

Houston Texans defensive end Jadeveon Clowney (90) wraps up Oakland Raiders fullback Jamize Olawale (49) during the second quarter of an NFL football game at Estadio Azteca on Monday, Nov. 21, 2016, in Mexico ... more

Photo: Brett Coomer, Staff

Image 4 of 7

Houston Texans defensive end Jadeveon Clowney (90) tries to stop Oakland Raiders running back Jalen Richard (30) during the first half of an NFL football game at Estadio Azteca on Monday, Nov. 21, 2016, in Mexico City. less

Houston Texans defensive end Jadeveon Clowney (90) tries to stop Oakland Raiders running back Jalen Richard (30) during the first half of an NFL football game at Estadio Azteca on Monday, Nov. 21, 2016, in ... more

Photo: Brett Coomer, Houston Chronicle

Image 5 of 7

Image 6 of 7

Houston Texans defensive end Jadeveon Clowney (90) tries to stop Oakland Raiders running back Jalen Richard (30) during the first half of an NFL football game at Estadio Azteca on Monday, Nov. 21, 2016, in Mexico City. less

Houston Texans defensive end Jadeveon Clowney (90) tries to stop Oakland Raiders running back Jalen Richard (30) during the first half of an NFL football game at Estadio Azteca on Monday, Nov. 21, 2016, in ... more

Photo: Brett Coomer, Houston Chronicle

Image 7 of 7

Bill O'Brien: Texans' Jadeveon Clowney will play Sunday

1 / 7

Back to Gallery

Texans starting defensive end Jadeveon Clowney practiced for the second consecutive day Friday and is now set to make his return Sunday against the Indianapolis Colts, according to coach Bill O'Brien.

Clowney is dealing with elbow and wrist injuries. The elbow injury is regarded as more of an issue than the wrist, but Clowney has battled through the pain throughout the season.

The former top overall pick was held out of the Texans' 21-13 loss to the Green Bay Packers at Lambeau Field in the hope that he could be healthier and available for this game.

Clowney won't be 100 percent, but expressed confidence that he will play Sunday at Lucas Oil Stadium in a pivotal AFC South showdown.

Clowney has recorded a career-high dozen tackles for losses this season. He has three sacks and 11 quarterback hits along with 41 tackles.