Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS

Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis

Y10S977/906—Drug delivery

Abstract

The present invention provides stable pharmaceutical compositions of poorly water soluble pharmaceutical agents and stabilizing agents which function to increase stability of the compositions. The use of stabilizing agents provide extended stability of nanoparticle suspensions and other formulations of poorly water soluble pharmaceutical agents such as docetaxel under certain conditions, for example upon dilution for administration.

PCT/US2006/0341032005-08-312006-08-30Compositions and methods for preparation of poorly water soluble drugs with increased stability
WO2007027941A2
(en)

Process for the preparation of the trihydrate of the (2R, 3S) -3-tertbutoxycarbonylamino-2-hydroxy-3-phenylpropionate-4-benzoyloxy-5beta acetoxy2alpha, 20epoxy-1,7beta, 10beta trihydroxy-9-oxo-tax-11-en -13alpha-yl