In vertebrates, the genes encoding the class of transcription
factors called homeobox genes are found in clusters named A, B, C,
and D on four separate chromosomes. Expression of these proteins is
spatially and temporally regulated during embryonic development.
This gene is part of the A cluster on chromosome 7 and encodes a
DNA-binding transcription factor that may regulate gene expression,
morphogenesis, and differentiation. More specifically, it may
function in fertility, embryo viability, and regulation of
hematopoietic lineage commitment. Alternatively spliced transcript
variants encoding different isoforms have been described.[3]