Well, Hitler isn't the only person to ever commit genocide but even so, a team actively stating they want to KILL pokémon is clearly never going to happen. Perhaps they might want to rid the region of them or strip them of their powers or something (and an evil team who hated pokémon would be interesting after the last few gens) but I do presume we'll be sticking to the world domination theme.

Maybe we'll even see an evil team who wants to turn the region into a monarchy. Reverse French Revolution, kind of. Team Aristocrat.

After someone mentioned Dialga/Palkia/Giratina, I'd love to see the Distortion World play a part. Not that I have any idea how it would, but it feels like something that could be explored a tad more than it was in Platinum.