The system can perform general cleanup tasks on a wide range of sample matrices such as foodstuffs, tissues, plants and environmental samples. High molecular weight compounds such as lipids, polymers, copolymers, proteins, natural resins, cellular components and steroids are easily dispersed and eliminated. The Smartline GPC Cleanup Unit 6500 combines a flexible modular design with intelligent, easy-to-use software. It can be easily adapted to pre-established laboratory procedures to perform a wide range of GPC sample preparation tasks while requiring only a very small amount of bench space.