Staff information

Keqi Tang

Biography

Dr. Keqi Tang is an electrospray ionization (ESI) mass spectrometry research scientist at Pacific Northwest National Laboratory (PNNL), where he develops technologies and methods for high performance hybrid mass spectrometry and its applications in chemical and biological analyses. Dr. Tang's current research advances ion mobility spectrometry (IMS) instrumentation methods for ultra-high throughput applications in system-biology studies; this research also includes developing a fundamental understanding of both conventional drift tube IMS and high field asymmetric waveform IMS through extensive theoretical modeling and experimental evaluation. Additionally, Dr. Tang is developing and implementing new ESI interfaces for high sensitivity mass spectrometry.

Dr. Tang has been a research scientist at PNNL from 2000. Prior to then, he was a research and development scientist at Thermo Finnigan LLC from 1997; a senior mechanical engineer at YSI Inc. from 1996; a postdoctoral fellow at PNNL from 1995; and a postdoctoral research associate at Yale University's Department of Mechanical Engineering from 1994.

Dr. Tang holds 12 issued U.S. patents, and is a significant contributor to his field with over 50 peer-reviewed publications and numerous invited and conference presentations.

Research Interests

Fundamentals of ESI and mass spectrometry applications

IMS and field asymmetric waveform IMS development

Mass spectrometric instrumentations including high-efficiency ion optics and liquid chromatography-mass spectrometry interface development for high throughput and high sensitivity ESI-mass spectrometry applications

Micro-fabrication technologies and their applications in micro electrospray arrays and micro fluidics

Biological applications of mass spectrometry including sample identification and quantification

Cox JT, I Marginean, RD Smith, and K Tang. 2015. "On the Ionization and Ion Transmission Efficiencies of Different ESI-MS Interfaces." Journal of the American Society for Mass Spectrometry 26(1):55-62. doi:10.1007/s13361-014-0998-5