Sovihep V

Sovihep V is an anti-hepatitis C viral medicine, containing active components known as Sofosbuvir and Velpatasvir available in the strength of 400mg & 100mg respectively.
Velpatasvir is a class of anti-hepatitis C viral drug, called NS5A multiplication complex inhibitors. This may have combined with other anti-viral agent Sofosbuvir which expels its work by stopping the virus which may causes hepatitis C viral infection from spreading inside the body.
Sovihep V tablet is not a curable; it is only used to control the spreading of disease.

Sofosbuvir & Velpatasvir

Sovihep V

400mg & 100mg

Zydus

Sovihep V indication and usage

Sovihep V tablets are used only in adult’s patients with long lasting hepatitis C virus caused by genotypes I, II, III, IV, V or VI
In two conditions Sovihep V tablets are used;

Without cirrhosis or with compensated cirrhosis (child Pugh A or B)
With decompensated cirrhosis by combining with ribavirin (child Pugh C)

Sovihep V mechanism of action

Both the components in Sovihep V tablets are involved in inhibiting nonstructural protein which is essential for viral multiplication.
Sofosbuvir is a NS5B inhibitor, whereas Velpatasvir is considered as NS5Ainhibitor
Sovihep V is a directly acting anti-hepatitis C viral agent.

The peak plasma concentration time of Sofosbuvir and Velpatasvir is 0.5 to 1 hour and 3 hours respectively.
The effect of food with Sovihep V tablet determines as;
With moderate meal: Sofosbuvir increases to 60%; increases to 34%
With high fat meal: Sofosbuvir increases to 78%; increases to 21%
The blood plasma ratio of Sofosbuvir & Velpatasvir is 0.7 & 0.52 to 0.67 respectively

Before initiation of therapy

Before starting the therapy, patient should be examined by counting hepatitis B surface antigen (HBsAg) and hepatitis B core antibody (anti-HBc) for confirmation of HBV infection.
The usual recommended dosage of Sovihep V tablet is one tablet should be administered as a single dose, by taking with or without food.

In new patients or experienced patients with or without cirrhosis

The prescribed dosage of Sovihep V in this condition is one tablet should be taken as a single dose.

In new or already treated patients with decompensated cirrhosis

The prescribed dosage of Sovihep V in this condition is one tablet to be taken as a single dose by combining with ribavirin.

The dosage of ribavirin

Based on body weight of the patients, the dosage of ribavirin should be recommended.
Less than 75kg: 1000mg of ribavirin should be recommended
At least 75kg: 1200mg of ribavirin should be recommended
Ribavirin must be administered with food.
Dosage adjustment should not be recommended in renal and hepatic impairment patients.

Over dosage

The over dosage of Sovihep V tablets;
If it occurs manage with supportive measures, and hemodialysis should be recommended for eliminating the components of Sovihep V and its metabolite.
Sofosbuvir is removed with the coefficient of 53%; Velpatasvir is highly bounds to human plasma protein and it is difficult to eliminate.

If Sovihep V dose is forgot to take, must consult with medical practitioner and follow the instruction. On the other hand, the missed dose should be skipped and follow the regular dosing schedule.

Quick Contact

Prescription upload

PRESCRIPTION

Blueberrypharma.com , a fully licensed and regulated pharmacy medicine, takes all precautions to strictly abide by the laws and regulations set forth in the dispensing of prescription medications. By placing the order for your prescription medicines, you acknowledge and accept the following terms regarding the purchase of any prescription medicines.

Blueberrypharma.com will not dispense any prescription medication without a valid prescription from a licensed physician.

If you are ordering prescription medication(s), you hereby confirm that you will send us a scanned copy of your valid prescription(s) via email, fax, Whatsapp, or by post, and this prescription shall then be subject to the scrutiny of and approval by our qualified Pharmacists.

The drug information provided in the Blueberrypharma.com is for informative purposes only and this Website is not intended to provide diagnosis, treatment or medical advice. We are not liable for any adverse effects or harm to you as a result of your reliance on the information in the Website.

Blueberrypharma.com requires either the User or Customer or the Caregiver to confirm he/she is completely aware of the indications, side effects, drug interactions, effects of missed dose or overdose of the medicines he/she orders from us. It is imperative to seek professional advice from your physician before purchasing or consuming any medicine from Blueberrypharma.com

At Blueberrypharma.com , a Caregiver can order prescription medicines on your behalf.

This information should not be used to decide whether or not to take this Product or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this Product . It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this product.