Cataplexy

Common Name(s)

Cataplexy

Cataplexy is a symptom shown only in people with narcolepsy. Cataplexy is a sudden loss of muscle tone while awake that makes you unable to move. Strong emotions, such as laughter or anger, can trigger this.
Most attacks last for less than 30 seconds and can be missed. Your head will suddenly fall forward, your jaw will become slack, and your knees will buckle. In severe cases, a person may fall and stay paralyzed for as long as several minutes.

Advocacy and Support Organizations

Condition Specific Organizations

Wake Up Narcolepsy is a 501(c)(3) not-for-profit organization dedicated to supporting narcolepsy awareness and research to find a cure. WUN carries out its mission by:
Providing funding to accelerate a cure for narcolepsy;
increasing awareness of narcolepsy;
decreasing time-lapse from symptom onset to proper diagnosis; and
providing supportive resources for people with narcolepsy and their families.

How do you compare to others with this condition?

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Advocacy and Support Organizations

Condition Specific Organizations

Following organizations serve the condition "Cataplexy" for support, advocacy or research.

Wake Up Narcolepsy is a 501(c)(3) not-for-profit organization dedicated to supporting narcolepsy awareness and research to find a cure. WUN carries out its mission by:
Providing funding to accelerate a cure for narcolepsy;
increasing awareness of narcolepsy;
decreasing time-lapse from symptom onset to proper diagnosis; and
providing supportive resources for people with narcolepsy and their families.

General Support Organizations

Recommended Apps

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

Finding the right clinical trial for Cataplexy can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cataplexy" returned 122 free, full-text research articles on human participants.
First 3 results:

Sodium oxybate is licensed in Europe for the treatment of narcolepsy with cataplexy in adults. The aim of this study was to assess the efficacy and safety of sodium oxybate in clinical practice in patients with narcolepsy and cataplexy refractory to other treatments.

Narcolepsy-cataplexy (NC) is a chronic neurological disease with suggested autoimmune etiopathogenesis. Nicotine stimulates central nervous system and smoking increases the risk of autoimmune diseases. Assessment of smoking habits and its correlation to clinical parameters among 87 ...

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cataplexy" returned 8 free, full-text review articles on human participants.
First 3 results:

According to ClinicalTrials.gov there are currently 4 additional "open" studies for "Cataplexy" (open studies are recruiting volunteers) and 29 "Cataplexy" studies with "all" status. Visit ClinicalTrials.gov now to view them. Or alternatively, consider TrialsFinder for assistance:

Relief is when you and the right researcher find each other
Finding the right clinical trial for Cataplexy can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.