To confirm that a significant proportion of patients will be prostate cancer free on the biopsy.

Changes in urinary and erectile functions and their potential impact on quality of life using International Prostate Symptom Score (IPSS), International Index of Erectile Function (IIEF) and the General quality of life (EQ5D) questionnaires.

Time to readiness for discharge from in hospital stay following treatment with SANGUINATE and Normal Saline.

Safety of treatment as defined by changes in vital signs, electrocardiographic, biochemical, hematological, and urinalysis measures, as well as reported increases in pain and other reported adverse events

Proportion of patients who develop acute chest syndrome (ACS) during the study.

Healthcare seeking behaviour of primary caregivers when their child was suspected of having an AOM episode.

Occurrence of suspected AOM based on symptoms reported by the primary caregiver.

Potential determinants (such as access to healthcare facilities) influencing healthcare seeking behaviour of primary caregivers who suspected their child aged 6 months to < 30 months of having an AOM episode during the last six months.

To compare the bacteriologic efficacy of 5-days of telithromycin to 10-days of penicillin V in subjects at the posttherapy/test-of-cure (TOC) visit in the per protocol population

To compare the bacteriologic efficacy of 5-days of telithromycin to 10-days of penicillin V in subjects at the posttherapy/test-of-cure (TOC) visit andlate posttherapy visit (Visit 4) in the bacteriologic modified intent to treat population