Browsing Research in Reproduction and Contraception, Center for by Author "Griswold, Michael D."

Sertoli cells are the somatic cells of the testis that are essential for
testis formation and spermatogenesis. Sertoli cells facilitate the
progression of germ cells to spermatozoa via direct contact and by
...

Clusterin is a glycoprotein that was initially isolated from the male
reproductive system. Subsequently, clusterin has been found to be widely
distributed in a variety of tissues in mammals. One characteristic ...

Spermatogonial stem cell transplantation is a novel technique in which
donor testicular cells are transferred into recipient testes. A population
of germ cells from a transgenic or mutant donor is introduced ...

The action of follicle-stimulating hormone (FSH) in spermatogenesis is
regulated at a fundamental level by controlling the number of competent
receptors present at the surface of Sertoli cells. By controlling ...

Adult germline stem cells are capable of self-renewal, tissue regeneration
and production of large numbers of differentiated progeny. We show here
that the classical mouse mutant luxoid affects adult germline ...

Spermatogonial transplantation as developed in the laboratory of Ralph
Brinster has been a technological breakthrough in the study of
Sertoli-germ cell interactions. For the first time, germ cells can be
...