Disrupting Today's Healthcare System

This week in San Diego, Singularity University is holding its Exponential Medicine Conference, a look at how technologists are redesigning and rebuilding today's broken healthcare system. Healthcare today is reactive, retrospective, bureaucratic and expensive. It's sick care, not healthcare. This blog is about why the $3 trillion healthcare system is broken and how we are going to fix it. First, the Bad News: Doctors spend $210 billion per year on procedures that aren’t based on patient need, but fear of liability. Americans spend, on average, $8,915 per person on healthcare – more than any other country on the planet. Prescription drugs cost around 50% more in the U.S. than in other industrialized countries. At current rates, by 2025, nearly ¼ of the US GDP will be spent on healthcare. It takes on average 12 years and $359 million to take a new drug from the lab to a patient. Only 5 in 5,000 of these new drugs make it to human testing. From there, only 1 of those 5 is actually approved for human use. And Now, the Good News: We are in the midst of a (medical) revolution driven by exponential technology: artificial intelligence, sensors, robotics, 3D printing, big data, genomics and stem cells. Today's $3 trillion healthcare industry is in the deceptive phase of its march towards dematerialization, demonetization and democratization. What does that mean? Imagine a time within the next 10 years when: AI-enabled autonomous health scans provide t...

Publication date: Available online 8 August 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): R. PranavKumar Shadamarshan, Harini Balaji, Harsha Shrihari Rao, K. Balagangadharan, S. Viji Chandran, N. SelvamuruganAbstractTrans-anethole (TA) is a phenolic phytocompound widely used in the food and health sector because of its diverse biological properties. However, its role in the promotion of bone formation is not known. With the enhanced bioavailability of TA, we aimed to determine its effect on osteogenesis; TA at different concentrations (5, 10, and 20 µM) was loaded onto polycaprolactone (PCL)/polyvinylp...

Publication date: Available online 14 August 2018Source: European Polymer JournalAuthor(s): Alba Martos, Rosa M. Sebastián, Jordi MarquetAbstractA wide set of differently substituted 3-phenyl-3,4-dihydro-2H-1,3-benzoxazine derivatives (models of thermosetting benzoxazine resins) were synthesized and their polymerization temperature was studied using Differential Scanning Calorimetry (DSC). The effect of the electronic properties of different substituents in different positions of the alkoxyphenyl ring on the polymerization temperature was analyzed by the Hammett equation. A non-linear Hammett plot was obtained indic...

In this study, axially {4-[3-(9H-carbazol-9-yl)propoxy]phenyl}methoxy and ({3,5-bis[3-(9H-carbazol-9-yl)propoxy]phenyl}methoxy) substituted silicon phthalocyanines were synthesized by reaction of SiPcCl2 with {4-[3-(9H-carbazol-9-yl)propoxy]phenyl}methanol and {3,5-bis[3-(9H-carbazol-9-yl)propoxy]phenyl}methanol in the presence of NaH in toluene. The new silicon phthalocyanines (SiPcs) were characterized by standard spectroscopy methods. Synthesized silicon phthalocyanines were electrochemically characterized with voltammetry techniques. The electrochemical studies exhibited that while SiPcs gave only Pc-based reduction pr...

Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN00804C, PaperNatalie Schwenk, Boris Mizaikoff, Soledad C árdenas, Ángela I. López-Lorente Aggregation of proteins has been related to some neurodegenerative diseases such as Alzheimer, and Parkinson among others. Raman spectroscopy is a useful technique for the investigation of protein conformation, and... The content of this RSS Feed (c) The Royal Society of Chemistry