Typically when a movie costs $35 million debuts at $44 million and then picks up an additional $60 million the following week, a sequel is a no-brainer. But in the case of “The Hangover,” part two talk began even before a dime was earned since Warner Bros knew they had a hit on their hands.

Now, $104 million later, planning on the Bradley Cooper starring sequel is moving full steam ahead. He told Extra that they plan to shoot it next fall — as for the plot, all he knows is they have to go big or go home!

“We’ve gotta go to space or something. Some weird things [have] to happen [to top the original],” Bradley said on the CFDA red carpet. And while it seems crazy to wait nearly a year to begin shooting, the next thing Bradley said seems even weirder.

“We’ll probably lose [Justin Bartha’s character] Doug again. I hope we lose Doug again. That’d be fun.” Really? I dunno, “Home Alone 2” barely got away with it and that’s only because they had Catherine O’Hara shout “we did it again!”

Hey, there’s an idea — rope in Catherine as someone’s mother, have her re-deliver that line and I’m sold!