I have always appreciated the use of toxidromes but personally find combining them with the setting and history even better…aka..the Poisontation!
60 y/o with several days worsening mental status – start by looking for Dig or Aspirin,
child found in a garage – toxic alcohol or pesticide
in my area (Chicago) teenaged female – APAP, diphenhydramine or buproprion
as common examples
Prison tox, hotel tox, etc