The results of the projects IVAO

The company IVAO announces the completion of the projects to the scientists who conduct research in
the field of life extension and longevity.

For consideration received 23 research project

The composition of the scientific Council

Alexey Moskalev

Expert against the aging of the company AI VAO

Professor of RAS, doctor of biological Sciences, head of laboratory of molecular radiobiology and gerontology
Institute of biology Komi SC UB RAS, head of the Department of ecology, Syktyvkar state
University, head of laboratory of genetics of longevity and aging in Moscow
Physico-Technical Institute. The author of more than 60 publications the areas of genetics of aging,
genetics, lifespan, radiation genetics. Researched the genome of Drosophila, including
genes in life expectancy. Member of the editorial boards of several scientific journals: Biogerontology, Frontiers
in Genetics of Aging, Aging.

Andrei Voronkov, Ph. D.

Director of science of the company AI VAO

Andrew has over 10 years experience of research in Biomedicine. On the end
graduate of Moscow state University, Andrew conducted research in the hospital of the University of Oslo, Norway.
In currently the company is run by Digital BioPharm Ltd., specializing in preclinical
the trials in the field of Oncology and diseases related to aging. In the project
IVAO Andrew oversees the section "Science". He also conducts research and reads
lectures in Moscow state University and MIPT. Andrew is the author of scientific publications in leading scientific
magazines and a holder of 2 patents. A. Voronkov graduated from the chemical faculty and graduate school
in Moscow State University.

Alexander Novikov, MBA

Director of the company's investment AI VAO

Alexander has 7 years of experience in the financial industry, which includes market
of shares, debt market, exchange-traded (ETD) and OTC derivatives (OTC). Before joining IVAO
he worked with brokerage companies (including Broco Investments) and banks (including
as the Northern Trust) to Russia and USA. The focus of his work was on alternative
the investment (foreign exchange market, exchange-traded (ETD) and OTC derivatives (Credit Default Swaps,
Interest Rate Swaps, Forwards). A. Novikov graduated from Keller Graduate School of Management
(Chicago, Il).

Congratulations to the winners!

First place was awarded to the project

MineGenics — diagnostic test for the early diagnosis and prevention
vascular calcification

Issues

In currently, cardiovascular diseases (CVD) year year
confidently occupy a leading position on the number of people it kills in developed developing
countries. CVD can be caused by improper lifestyle, genetic
predisposition and metabolic abnormalities of the patients. GCC shows the age,
and already every second man older than 40 years are the first signs
CVD most Often, the cardiovascular system loses its elasticity, and functionality
which is caused by the accumulation of calcium salts and formation of structures resembling bone in soft
the tissues of the vessels and heart patient. In patients with calcification in a few
times higher risk of death from heart and in surgical operations on the heart.

In the risk of developing calcification is hundreds of millions of people around the world,
among patients with atherosclerosis, diabetes, chronic renal
failure and osteoporosis. For the last 20 years of research world
the scientific community has recognized the serious calcification and widespread pathology
cardiovascular system that needs to be treated. We are analyzed the data
patients and literature, come to the conclusion that by calcification lead
changes in a variety of molecular mechanisms. Moreover, calcification in late
irreversible stages, and patients can only treat the symptoms. In connection the,
we have developed a personalized approach to prevent the development of calcinosis.

Technological innovation and innovation

Diagnostic test system provides information about the likelihood of calcinate
and recommendations to prevent the development of calcification of CVD on the basis of the analysis
selected RNA blood markers, genetic data and the results of biochemical tests
patient. For through personalized approach and multi-factor analysis, we plan
to increase the effectiveness of therapy and significantly reduce the likelihood of developing calcinosis in patients,
who will benefit from our product.

product Description

The diagnostic system consists of a platform and panel of primers for the detection of
RNA markers of calcification in the patient's blood. Diagnosis of the patient begins with the selection
1 ml of blood, preparation of material and analysis using the technology
cat-PCR with the aim of determining the values of RNA markers in the patient. Then the doctor makes
data markers of calcification, biochemical and genetic patient data in the web framework "MineGenics".
Founded in the platform, the algorithm calculates the probability of development of calcinosis in the patient
warns of the first signs of calcification and provides recommendations
medicines and dietary Supplements for the prevention of calcification of cardiovascular system.

Market

The diagnostic system consists of a platform and panel of primers for the detection of
RNA markers of calcification in the patient's blood. Diagnosis of the patient begins with the selection
1 ml of blood, preparation of material and analysis using the technology
cat-PCR with the aim of determining the values of RNA markers in the patient. Then the doctor makes
data markers of calcification, biochemical and genetic patient data in the web framework "MineGenics".
Founded in the platform, the algorithm calculates the probability of development of calcinosis in the patient
warns of the first signs of calcification and provides recommendations
medicines and dietary Supplements for the prevention of calcification of cardiovascular system.

a Comparative analysis with Russian and international competition

the moment, the only way to get rid of calcification CCC remains
surgery for the removal of the affected area and installing the endoprosthesis
(if possible). Such surgical operations are carried out in $ 100 PCs.
in month. On the external market also developing competitive diagnostic
system in the company Calciscon, which allows to determine the susceptibility of the patient
to calcification on the basis of the analysis of biochemical characteristics of plasma, blood
the patient with using nephelometry with resolution time (atypical
a device for therapeutic and diagnostic institutions, hinders the widespread dissemination
method in clinical practice).

Specialist in the field of molecular biology and bioinformatics, PhD student, faculty of
of bioengineering and bioinformatics, Lomonosov Moscow state University. M. V. Lomonosov. Author of 6 scientific publications
in the field of molecular biology and bioinformatics, the winner of the grant of the President of the Russian Federation,
the winner of the award with the medal of RAS for young scientists and students, the winner
scholarships MSU M. V. Lomonosov Moscow state University for talented young scientists and graduate students.

Apple iPhone 6s 64GB (розовое золото)

Mkrtchyan Garik vardanovich

Director of science technology co., LTD «MineGenics"

Specialist in the field of medical biochemistry and bioinformatics, postgraduate student of the faculty
of bioengineering and bioinformatics, Lomonosov Moscow state University. M. V. Lomonosov is the Author of 6 scientific publications in the field
biochemistry and bioinformatics, winner of the scholarship MSU M. V. Lomonosov Moscow state University for talented
young scientists and graduate students.

The project partners

Biological fakultetet MSU M. V. Lomonosov (Russia)

FSCC phoi n. Dmitry Rogachev (Russia)

Bioinformatics Institute A-STAR (Singapore)

University of southern California (USA)

Special prizes from AI HLW

PocketBook 626 Plus (white)

“the Technology used to extend life and protection cancer»

The project of the Stavropol State Medical University
Project Manager — albert Belatchew

E-book Digma E628 (black)

"Mobile app to provide first medical aid for injuries and damages
different Genesis"