The Biomarker Discovery is intended for molecular biology applications. This product is neither intended for the diagnosis, prevention, or treatment of a disease, nor has it been validated for such use either alone or in combination with other products.

Our RNA profiling services enable you to analyze both coding and non-coding RNAs in one place.

Unrivalled expertise in liquid biopsies

Our liquid biopsy expertise include:

Protocols optimized for liquid biopsies, from isolation to data analysis

A detailed knowledge of biofluid preanalytical variables

Biofluid reference ranges

Specialized biofluid QC procedures

Our proprietary QC and data analysis pipelines for liquid biopsy samples, as a result of our extensive research, offer an unrivaled level of specialized expertise.

Comprehensive RNA analysis services

Our expertise in the analysis of RNA, combined with experience from our biomarker discovery programs, means that we are ideally suited to offer the best recommendations for your RNA biomarker discovery programs. Every project begins with an in-depth consultation where we discuss the experimental design strategy, number of individuals, sample collection and profiling technologies. We offer a complete Sample to Insight service, including everything from RNA isolation to extensive customized data analysis.

RNA biomarker discovery and validation services

Our Custom Pharma Services provide options for biomarker discovery across different platforms (e.g., NGS and qPCR). QIAGEN's bioinformaticians have developed effective strategies to identify and test RNA signatures for a range of biomarker applications.

Biomarker discovery workflow

Biomarker discovery projects usually start with genome-wide screening on a few samples, performed either by a hypothesis-free NGS approach or PCR profiling. From this dataset, a smaller number of relevant RNAs are identified, and the discovery phase can continue. Once a biomarker signature has been identified (including relevant endogenous control RNAs), it is then validated on a large number of samples using custom miRCURY LNA PCR panels. Crucially, assays to detect any novel RNAs identified by NGS may also be included in the custom PCR panels.