Sildenafil belongs to a class of pills called phosphodiesterase type 5 (PDE5) inhibitors. A class of medicines is a group of drugs that work similarly. These drugs are often used to treat similar situations. Sildenafil acts in different ways, depending on the condition it’s being used to treat.

For PAH: Sildenafil works by relaxing the muscles and opening up the blood vessels in your lungs. This decreases the blood pressure in your lungs. Sildenafil slows down the progress of your illness. It also gives you more able to exercise.

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