Brain's 'Pain Meter' Identified

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The brain's "pain sensor" has been found, researchers say. When
you step on a thumbtack or hit your funny bone, this is the part
of your brain that lights up.

Researchers conducted imaging scans of the brains of people who
were experiencing pain waxing and waning over several hours. They
identified a region of the brain called the dorsal posterior
insula, which became active in response
to how much pain a person felt.

"We have identified the brain area likely to be responsible for
the core 'it hurts' experience of pain," Irene Tracey, who is the
lead author of the study and a professor of anesthetic science at
the University of Oxford in England, said in a
statement.

The findings could someday help doctors detect pain in people who
lack the ability to communicate well, such as small children or
people in a coma or who have dementia, the researchers said in
the study, published today (March 9) in the journal Nature
Neuroscience. [ 5
Surprising Facts About Pain ]

In the study, Tracey and her colleagues rubbed a cream containing
the chemical
capsaicin — the compound in chili peppers that causes a
burning sensation — onto the legs of 17 healthy volunteers. The
researchers then placed a hot or cold water bottle against the
volunteers' skin to increase or decrease their pain level,
respectively.

Meanwhile, the researchers scanned the participants' brains and
asked them to rate how much pain they felt.

They found that the dorsal posterior insula glowed more in the
brain scans when the volunteers reported the most pain,
suggesting this region acts as a kind of pain meter in the brain,
researchers said.

Next, the researchers plan to test whether it's possible to
"switch off" this brain region in people who suffer from
intractable pain, for whom other treatments have failed.