Mayo Clinic study shows that high-intensity aerobic exercise performed in short intervals can reverse the aging processes.

The Mayo Clinic has determined that intense aerobic exercise has the potential to reverse the aging process in adults. Though everyone knows exercise is beneficial, there are plenty of questions regarding which types of exercises are the best and what age groups benefit the most from specific exercises. According to the Mayo Clinic, high intensity cardio can reverse some cellular aspects of aging The Study’s Aim:

The purpose of the study described above was to pinpoint evidence that would assist in the development of exercise recommendations and targeted therapies for people of varying ages. Researchers monitored molecular and metabolic alterations in individuals of varying ages across a period of about three months. They collected data 72 hours after those in randomized groups performed an array of different exercises.

Study Details:

Mayo Clinic researchers tested high-intensity interval training (HIIT) against combined training and resistance training. Each style of training boosted lean body mass as well as insulin sensitivity. However, HIIT and combined training heightened aerobic capacity as well as mitochondrial functionality for skeletal muscle. This is especially important for senior citizens who often endure declines in mitochondrial content and functionality. HIIT even boosted muscle protein content that improved energetic functions and spurred the enlargement of muscles. This bolstering of muscle protein was common in older adults who engaged in high-intensity intervals. The research team keyed in on one of their most important findings: exercise boosted the cellular machinery necessary for the construction of new proteins. Protein creation and synthesis reverse some of the problematic effects of the aging process. The take-home message is that HIIT is ideal for aging adults as it benefits the body at the molecular level as well as metabolically. HIIT reverses certain manifestations of the aging process within the human body’s protein function. Engaging in resistance training is also advisable as it allows for the establishment of considerable muscle strength. HIIT is certainly beneficial yet a strict reliance on this style of exercise won’t significantly boost muscle strength unless combined with resistance training.

More Details About the Findings:

The researchers found that training has minimal effect on DNA energy transfer within skeletal muscle but facilitated such muscle protein expression to a high degree in older individuals. Though mitochondrial cell functionality dissipates with age, it heightens with training. Exercise drastically increased ribosomal proteins designed to boost new proteins. Exercise also heightened skeletal muscle gene expression regardless of age.

In males, the main biologically active estrogen is estradiol. The primary source of estradiol in men is from the conversion (aromatization) of testosterone. As men age, the production of androgens from the adrenals and gonads is decreased. The aromatization of testosterone to estradiol is often maintained, but due to a variety of factors, more testosterone is aromatized in fatty tissues, causing a further imbalance of the ratio of testosterone to estrogen, i.e. too much estradiol and not enough testosterone. The result is a deficiency of beneficial testosterone and an excess amount of estradiol.34
As men age, the amount of testosterone produced in the testes diminishes greatly. Yet estradiol levels remain persistently high. The reason for this is increasing aromatase activity along with age-associated fat mass, especially in the belly.5 Estradiol levels correlate significantly to body fat mass and more specifically to subcutaneous abdominal fat. The epidemic of abdominal obesity observed in aging men is associated with a constellation of degenerative disorders, including heart disease, diabetes, and cancer.9,35-38
Subcutaneous abdominal fat acts as a secretory gland, often producing and emitting excessive levels of estradiol into an aging man’s blood.39 One’s waist circumference is a highly accurate prognostic measurement of future disease risk, with excess estradiol secretion being at least one of the deadly mechanisms associated with the difficult-to-resolve problem of having too much abdominal fat.5,40
Symptoms of excess estrogen in aging men include the development of breasts, having too much abdominal weight, feeling tired, suffering loss of muscle mass, and having emotional disturbances. Many of these symptoms correspond to testosterone deficiency as well.41
PROTECTING AGAINST TOXIC ESTROGEN METABOLITES
It is not just excess estradiol that poses health risks. Specific estrogen metabolites may also initiate and promote hormone-related cancers. Daily consumption of cruciferous vegetables (broccoli, cauliflower, cabbage, Brussels sprouts),54-59 along with isoflavone-rich soy foods60-64 converts these dangerous estrogen metabolites (such as 16-alpha-hydroxyestrone) to safe ones (2-hydroxyestrone) that may protect against prostate cancer.
For those who don’t eat these cancer-protective foods on a daily basis, low-cost supplements can supply the most active constituents of cruciferous vegetables (such as indole-3-carbinol and sulphoraphane)65-70 and soy (genistein and daidzein).71-74
Don’t Lower Your Estrogen Too Much!
When reviewing the studies about the multiple pathological effects of excess estrogen in aging men, it may be tempting to take high doses of an aromatase-inhibiting drug (like Arimidex®) to slash estrogen levels as low as possible. Don’t do this, as men need estrogen to maintain bone density, cognitive function, and even to maintain the inner lining of the arterial wall (the endothelium).42
Most age management health specialist know that too little cholesterol (below 150 mg/dL) can be more dangerous than too much cholesterol (levels over 200 mg/dL). The same may hold true for estrogen. We have recommended that ideal ranges for estradiol for most aging men are between 20 and 30 pg/mL of blood. Below 18 pg/mL increases osteoporosis risk, while levels greater than 30 pg/mL increase heart attack and stroke incidence.
The availability of low-cost blood tests enables aging men to optimize their estradiol levels using natural approaches and/or prescription drugs.
Estrogen and Men’s Bones
Osteoporosis is not just a risk for aging women. Men also suffer crippling fractures caused by loss of bone mineral density. When aged men suffer a bone fracture, their risk of dying is significantly higher than women.43,44
In a study published two years ago, doctors analyzed blood levels in three groups of men for estradiol only, testosterone only, and estradiol and testosterone together. In men with low estradiol (2.0-18.1 pg/mL of blood), hip fractures were more than three times higher compared with men who had estradiol levels of 18.2-34.2 pg/mL.45
Men with estradiol levels greater than 34.3 pg/mL had a slightly higher risk of hip fracture compared with those in the range of 18.2-34.2 pg/mL. This study helps confirm age management specialists recommended range for estrogen levels in aging men.
Interestingly, this study also showed in the group of men whose blood was measured for estradiol and testosterone, those who were low in both these hormones suffered a startling 6.5 times greater incidence of hip fractures. The authors of this study concluded, “men with low estradiol levels are at an increased risk for future hip fracture. Men with both low estradiol and low testosterone levels seem to be at greatest risk for hip fracture.”45
Conflicting Data
With the voluminous amount of scientific studies being published today, contradictions inevitably arise, and this is not always due to study design flaws.

For the past decade, age management specialists have reported on dozens of studies showing that higher testosterone levels significantly reduce a man’s risk of cardiovascular disease. In fact, after a comprehensive database search and identified a total of 50 studies that document the protective effects of testosterone against cardiovascular disease in men.
A study published two years ago, however, contradicts this. This study showed greater incidences of heart attacks in men with higher testosterone and lower heart attack risks in older men with higher estradiol. (In younger men, estradiol level had no impact on heart attack incidence in this study.) The authors of the study admitted a limitation to the study was only measuring baseline levels of hormones. This study nonetheless was used at the anti-aging conference to proclaim that estradiol protects against heart attack.46
There are scientific studies that demonstrate estrogen’s potential beneficial effects to a man’s vascular system. These protective mechanisms, however, have to be weighed against pathological damage the very same estrogen can induce.
As mentioned earlier, despite the documented dangers of excess estrogen, levels that are too low also present risks, not only to bone,45,47-49 but to the vascular system as well.46,50,51 If a man were to intentionally lower his estradiol too much, he could very well suffer vascular disease because estrogen is vital to proper endothelial function.52,53
This is why it is so important for aging men to have annual blood tests. If estrogen is too low (below 18-20 pg/mL), or too high (above 30 pg/mL), corrective action should be taken.
How to Reduce Excess Estrogen
In aging men, a large percentage of estradiol is synthesized in abdominal adipose (fat) tissues.42 Reducing waist circumference confers huge health benefits, one being a lowering of estradiol levels.
One of the most effective ways for men to reduce belly fat is to restore their free testosterone to youthful ranges. Nutrients that inhibit the aromatase enzyme can help boost testosterone levels by preventing its conversion (aromatization) into estradiol.
As men grow older, however, their testicular testosterone production declines precipitously. This means that inhibiting aromatase might not sufficiently maintain testosterone levels because not enough is being produced internally. Fortunately, low-cost compounded testosterone creams are available that can be rubbed on the skin for absorption into the bloodstream.
For men with excess aromatase activity, this topically absorbed testosterone might convert into too much estradiol. If this happens, the use of very low-dose aromatase-inhibiting drugs (0.5 mg of Arimidex® twice a week) may be all that is needed to protect against estrogen overload. Some men don’t need these drugs and can use nutrient formulas that have aromatase-inhibiting properties.
There is no need to guess what you need, as a blood test taken 30-45 days after initiating testosterone-replacement not only reveals a man’s estradiol level, but also ensures that the PSA has not spiked (indicating possible pre-existing prostate cancer), that the dose of testosterone cream is appropriate, and that there are no other side effects occurring. .
What if Your Estrogen Level is Too Low?
Some men are so deficient in aromatase that they do not make enough estrogen.
If a blood test reveals estradiol below 20 pg/mL, which may occur if Arimidex®, for example, is being taken at too high a dose, one should consider reducing the dose. Alternatively, applying a tiny dose of a compounded topical estradiol cream to the skin several times a week may also help increase estradiol levels. Follow-up blood tests 30-45 days later can assess if too much or too little topical estradiol cream is being used.
There is also evidence that consuming phytoestrogens from soy might provide similar benefits for the bone75-79 and vascular system.80-88
Summary

It is hard to imagine that before 1906, doctors did not even know that a hormone (estrogen) was secreted by the ovaries in women. It was not until 1930 that the isolation of the estrogen complex in pure form was published.
Less than 80 years later, scientists are debating what the optimal levels of estrogen should be in men. This exponential leap in scientific knowledge is a marvel in itself!
The role that estrogen plays in men’s health is an important topic discussed at medical conferences today. As outlined in this article, testing one’s estradiol level is critical because it can be a serious problem if it is too high or if it is too low.
If the results reveal estradiol levels are too high or too low, corrective measures can easily be taken to protect your precious health.

There seems to be a common misconception among physicians and patients that all hormones are the same. Of course, this is not true, but it shows the pharmaceutical propaganda machine is working. The basic difference between chemical hormones and bio-identical hormones is that one has side-effects and the other does not. This is because side-effects are a property of drugs not foods. Consequently, it follows that hormones obtained from natural food sources, also known as “bio-identical hormones,” do not have the same negative effects associated with synthetic hormone drug products.

The most common prescription hormone drugs include various forms of estrogen and progestin, a synthetic progesterone that acts more like estrogen than progesterone. Female patients are typically prescribed these synthetic hormone drugs to help with their menstrual cycle or menopause. In general, estrogen has a very broad physiological role for males as well as females. The effects of estrogen include, but are not limited to, the following: water retention, aging, stress, memory loss, hypoglycemia, increased fat, hypothyroidism, miscarriage, infertility, uterine fibroids, blood clotting, vascular spasm, increased cholesterol, gall bladder disease, and cancer.

The main cause of hormone-related health problems in women is not due to the absolute deficiency of estrogen or progesterone but rather the relative dominance of estrogen and relative deficiency of progesterone. For this reason, hormone replacement therapy (HRT) with estrogen alone without an opposing progesterone, such as the prescription drug Premarin, should be avoided. This chemicalized hormonal substitute differs from the natural estrogen in one’s body and contributes to increased estrogen. Increased estrogen, in turn, increases the risk of DNA damage, cancer (e.g., endometrial, breast cancer, etc.), and estrogen dominance. Other contributing factors to excess estrogen include adrenal fatigue, environmental estrogen, obesity, stress, poor diet, and lack of exercise.

Estrogen excess may result in such common maladies as depression, weight gain insomnia, anxiety, blood sugar imbalance, migraine headaches, and chronic fatigue due to adrenal gland exhaustion. Moreover, stress can result not only in adrenal gland exhaustion, but reduced progesterone output and increased estrogen production. A further reduction in progesterone output contributes to all the problems associated estrogen dominance (“Acute stress persistently enhances estrogen levels in the female rat,” Shors et al., Stress. 3(2):163-71, 1999

Interestingly, nature has provided us with progesterone, which acts as an antagonist to estrogen. For example, estrogen stimulates breast cysts while progesterone protects against breast cysts. Estrogen enhances salt and water retention while progesterone is a natural diuretic. Estrogen is associated with breast and endometrial cancers, while progesterone has a cancer preventive effect. In fact, studies have shown that premenopausal women deficient in progesterone had 5.4 times the risk of breast cancer compared to healthy women (“Breast cancer incidence in women with a history of progesterone deficiency,” Cowan et al., Am J Epidemiol, 114(2):209-17, Aug 1981).

Here are some answers to frequently asked questions that patients have about progesterone:

1. Is progesterone supplementation safe? Yes. No side effects have been attributed to bio-identical natural progesterone in either the scientific or medical literature. While large doses of estrogen have been found to destroy certain areas of the adrenal cortex, large doses of progesterone have been shown to have anti-stress effects without harming the adrenals.

2. Should I take progesterone if I’m pregnant? A “Medical News” item in a 1976 issue of JAMA reports a study showing that progesterone probably plays a critical role in preventing rejection of the fetus by the mother. Its use before and during pregnancy is also associated with a reduced incidence of birth defects. Studies in animals have also shown that prenatal progesterone increases brain size, which is associated with a long life. Conversely, excess estrogen reduces brain size and damages behavior, which may, in turn, adversely affect a subsequent generation (“The Epigenetics of Sex Differences in the Brain,” McCarthy et al.J Neurosci. 2009 Oct 14; 29(41):12815–12823).

3. Can I use progesterone for weight loss? Yes. The primary reasons for using progesterone for weight loss purposes are to decrease the effects of insulin and adrenaline. This is because insulin transports sugar into the fat tissue for storage which, in turn, stimulates the release of adrenaline to raise sugar levels again creating a positive feedback loop. Consequently, as the episodes of hypoglycemia decrease the production of adrenaline to counteract hypoglycemia also decreases. Decreased adrenaline means that less sugar is produced, less insulin is needed for storing sugar as fat, and thus, more weight can be lost.

4. Does progesterone help with insomnia? Yes. Progesterone, which is most highly concentrated in the brain tissue, increases GABA production in the brain which, in turn, promotes sleep.

Increase Human Growth Hormone Safely and More Effectively

By Using Sermorelin Acetate:

Sermorelin(GHRH) is a bio-identical hormone that has recently been genetically engineered to stimulate the secretion of Growth Hormone Releasing Hormone (GHRH) from the hypothalamus, a gland adjacent to the pituitary gland.

GHRH is a peptide that contains the first 29 amino acids of our own GH. These 29 amino acids are the active amino acids of GHRH. It is GHRH that stimulates the pituitary glands to release GH. As we get older, the hormones produced by the anterior pituitary are depleted. It has now been shown that GHRH can restore the GH-RNA to a youthful level causing elevation of levels of IGF-1.

How does Sermorelin come?

Sermorelin is presented in a multi-dosed, injectable vial. Each vial contains a powder disc which contains 15mg (15,000 micrograms) of lyophilized Sermorelin Acetate. The vial is vacuum sealed by the pharmacy for your protection and for the preservation of the hormone peptide. Each Sermorelin vial also comes with a bottle of Bacteriostatic Water as a diluent. The Bacteriostatic Water is mixed with the Sermorelin to provide solution for injection. Administration and storage instructions will be provided with your prescription.

How do I take Sermorelin?

Sermorelin is injected into the body fat, subcutaneously, using a very small needle similar to what a diabetic uses to inject insulin. Injections are initially prescribed for every day and are decreased in frequency over time.

When do I take Sermorelin?

The best time to take Sermorelin is prior to bedtime. Growth Hormone is primarily released during sleep and most beneficial to the body’s recovery and repair during this time. Sermorelin has a promoting effect on sleep and can therefore make you tired if taken during the day.

How do you measure the effectiveness of Sermorelin?

Due to the pulsatile nature of both endogenous HGH and IGF-1, a single blood draw is not sufficient for accurate measurement. Most physicians who prescribe Sermorelin and similar peptides measure effectiveness in patients through symptomology (the study of your symptoms-see benefits); physical appearance and measurements; and more frequent blood analysis.

How will I know its working?

After 4 years of observing patients taking Sermorelin, I have noticed that patients usually report improved sleep within the first few weeks of therapy. Of course, this is only noticed in patients who have trouble sleeping in the first place, however most patients at least notice an increase in sleep quality. This is usually concurrent with increased energy levels and improved mood. After 3-6 months of therapy patients start reporting noticeable or significant body changes, such as increase in muscle tone and a leaner physique. Over time patients will also notice a significant improvement in skin tone and health.

How long does it take to work?

Just like most peptide hormones, Sermorelin usually has a “loading” period of 3-6 months before full effects are noticed. Once injected, both Sermorelin and rHGH are eliminated from then body very quickly and therefore need to be injected frequently. Its actions are dependent on a chain reaction of biological processes which result in elevated and sustained HGH and growth factors. It takes some time for levels to become optimal and initiate the benefits we are seeking to achieve.

Do I need to take Sermorelin forever to keep seeing results?

Actually, no. Sermorelin has an ongoing effect in which optimal HGH levels can be sustained long after the last injection. Just like synthetic HGH, Sermorelin initially must be injected every day. Unlike synthetic HGH, once optimal levels are sustained with Sermorelin injection frequencies can be decreased or stopped altogether. Once results are achieved, patients are then switched to a maintenance protocol eliminating the need for ongoing daily injections and reducing the total cost of therapy!

Do you want to find out more about Anti-Aging and to locate a Physician in your hometown, check this group out……

The American Academy of Anti-Aging Medicine (A4M), http://www.A4m.com, is a US federally registered 501(c) 3 non-profit organization comprised of over 26,000 members including: physicians, health practitioners, scientists, governmental officials, and members of the general public, representing over 110 nations.

The A4M is dedicated to the advancement of technology to detect, prevent, and treat aging related disease and to promote research into methods to retard and optimize the human aging process. The A4M is also dedicated to educating physicians, scientists, and members of the public on biomedical sciences, breaking technologies, and anti-aging issues.

In 1976, futurists Joel Kurtzman and Philip Gordon wrote No More Dying. The Conquest Of Aging And The Extension Of Human Life, (ISBN 0-440-36247-4) the first popular book on research to extend human lifespan. Subsequently, Kurtzman was invited to testify before the House Select Committee on Aging, chaired by Claude Pepper of Florida, to discuss the impact of life extension on the Social Security system.

In 1983, Roy Walford, a life-extensionist and gerontologist, published a popular book called Maximum Lifespan. In 1988, Walford and his student Richard Weindruch summarized their research into the ability of calorie restriction to extend the lifespan of rodents in The Retardation of Aging and Disease by Dietary Restriction (ISBN 0-398-05496-7). It had been known since the work of Clive McCay in the 1930s that calorie restriction can extend the maximum lifespan of rodents. But it was the work of Walford and Weindruch that gave detailed scientific grounding to that knowledge. Walford’s personal interest in life extension motivated his scientific work and he practiced calorie restriction himself. Walford died at the age of 80 from complications caused by amyotrophic lateral sclerosis.

Money generated by the non-profit Life Extension Foundation allowed Saul Kent to finance the Alcor Life Extension Foundation, the world’s largest cryonics organization. The cryonics movement had been launched in 1962 by Robert Ettinger‘s book, The Prospect of Immortality. In the 1960s, Saul Kent had been a co-founder of the Cryonics Society of New York. Alcor gained national prominence when baseball star Ted Williams was cryonically preserved by Alcor in 2002 and a family dispute arose as to whether Williams had really wanted to be cryopreserved.

Regulatory and legal struggles between the Food and Drug Administration (FDA) and the Life Extension Foundation included seizure of merchandise and court action. In 1991, Saul Kent and Bill Faloon, the principals of the Foundation, were jailed. The LEF accused the FDA of perpetrating a “Holocaust” and “seeking gestapo-like power” through its regulation of drugs and marketing claims.[91]

In 2003, Doubleday published “The Immortal Cell: One Scientist’s Quest to Solve the Mystery of Human Aging,” by Michael D. West. West emphasised the potential role of embryonic stem cells in life extension.

Ethics and politics of life extension

Though many scientists state that life extension and radical life extension are possible, there are still no international or national programs focused on radical life extension. There are political forces staying for and against life extension. By 2012, in Russia, the United States, Israel, and the Netherlands, the Longevity political parties started. They aimed to provide political support to radical life extension research and technologies, and ensure the fastest possible and at the same time soft transition of society to the next step – life without aging and with radical life extension, and to provide access to such technologies to most currently living people.

“simply to covet a prolonged life span for ourselves is both a sign and a cause of our failure to open ourselves to procreation and to any higher purpose … [The] desire to prolong youthfulness is not only a childish desire to eat one’s life and keep it; it is also an expression of a childish and narcissistic wish incompatible with devotion to posterity.”

John Harris, former editor-in-chief of the Journal of Medical Ethics, argues that as long as life is worth living, according to the person himself, we have a powerful moral imperative to save the life and thus to develop and offer life extension therapies to those who want them.

TranshumanistphilosopherNick Bostrom has argued that any technological advances in life extension must be equitably distributed and not restricted to a privileged few. In an extended metaphor entitled “The Fable of the Dragon-Tyrant”, Bostrom envisions death as a monstrous dragon who demands human sacrifices. In the fable, after a lengthy debate between those who believe the dragon is a fact of life and those who believe the dragon can and should be destroyed, the dragon is finally killed. Bostrom argues that political inaction allowed many preventable human deaths to occur.Aging as a disease

Most mainstream medical organizations and practitioners do not consider aging to be a disease. David Sinclair says: “I don’t see aging as a disease, but as a collection of quite predictable diseases caused by the deterioration of the body”. The two main arguments used are that aging is both inevitable and universal while diseases are not. However not everyone agrees. Harry R. Moody, Director of Academic Affairs for AARP, notes that what is normal and what is disease strongly depends on a historical context. David Gems, Assistant Director of the Institute of Healthy Ageing, strongly argues that aging should be viewed as a disease. In response to the universality of aging, David Gems notes that it is as misleading as arguing that Basenji are not dogs because they do not bark. Because of the universality of aging he calls it a ‘special sort of disease’. Robert M. Perlman, coined the terms ‘aging syndrome’ and ‘disease complex’ in 1954 to describe aging.

The discussion whether aging should be viewed as a disease or not has important implications. It would stimulate pharmaceutical companies to develop life extension therapies and in the United States of America, it would also increase the regulation of the anti-aging market by the FDA. Anti-aging now falls under the regulations for cosmetic medicine which are less tight than those for drugs.

We all have a small gland deep within our brain called the hypothalamus. It is a vital part of the body which controls all of our autonomic functions, including breathing, heartbeat, digestion, sleep and the complicated functions of the endocrine [hormone] systems. Included in these endocrine functions are the regulation and control of metabolism and weight.

HCG mimics the effects of luteinizing hormone. HCG mobilizes fat and makes it available to the body as an energy source. It naturally reduces appetite. So combined with low calorie diet, the body is signaled to use fat that is stored for energy and for elimination from the body. So it reduces the body of abnormal fat.

Optimizing the production and secretion of GH is a great addition to any fitness regimen. It has been shown to raise cortisol levels in those with poorly functioning adrenal glands, and helps conditions such as fibromyalgia, chronic fatigue, depression and obesity. Other benefits are: improve fat burning, improve skin elasticity, aids in connective tissue repair post-injury, improves quality of sleep, and increases bone density through calcium retention.

The combination of GHRP-6 and HCG have proven to be a powerful opportunity for the area of anti-aging medicine and hormone support. Reports show that the administration of both together is more effective than when administered individually. HCG-RAS has shown favorable results of: increase libido, hormone balancing, increase metabolism, weight loss combined with nutritional program, decreased pain in fibromyalgia patient and reduction of cholesterol levels.

Telomere testing evaluates your health at the cellular level, is the best measure of the current length of a chromosome’s telomeres and has proven to be the most accurate method of determining your biological versus chronological age. It also provides a critical understanding of how lifestyle habits are impacting your health, further informing the development of a truly personalized and targeted age management Program.

By analyzing your cell’s ability to duplicate itself, this revolutionary procedure provides you and your physician with critical data about your body. When a cell replicates, its telomere is shortened and the life span of the cell is reduced. Poor lifestyle factors—smoking, unmanaged stress, being overweight, lack of exercise—can accelerate telomere shortening over time to the point where a cell cannot function properly. When cells can no longer divide, they die, and the risk of disease and premature aging increase.

What are Telomeres?

Molecular markers for aging—the more short telomeres you have, the biologically “older” you are

The Life Length® Telomere Test

Telomere Analysis, provide by Dr. James Procelli’s “Metabolics” Age Management program from Naples Florida measures the percentage of short telomeres in individual cells. This percentage is the most relevant indicator of telomere dysfunction and cellular aging.

Testing begins with a simple blood test—no fasting or special preparations necessary. Within a few weeks, you are able to review the detailed results with your Metabolics representative/physician to learn your estimated biological age and fine-tune your Age Managment Program to improve or maintain cellular health.