I've done it, 3-4 times, depending on how you look at one of the moves. it depends on how you leverage it - I basically went from training people to use arms, to selling the services, to selling used military medical equipment, to selling medical equipment, to selling software, to selling communications systems, back to medical equipment, then back to communications systems.

I like the rule that with a move you can either change jobs or change industries.

Almost impossible to do both at the same time and sometimes just accomplishing any change requires a new degree.

Is it possible to change jobs within your industry, with a longer term goal of switching out of industry with your new job title?

Ugh. That rule is what is making my search for an exit strategy so miserable.

I have tried several times to switch roles, and it isn't working. Interviews are not going well. I keep getting passed away from the position I apply for and back towards the position I have. So I think the only way out is to change industries so that I'm not seen as more valuable in my current role (math/physics geek, med device stuff).