Having the motto “work for poorest of the poor”, NeRuDO believes that the basic problems of wide-scale and deep rooted poverty and the resultant backwardness cannot be addressed through Government’s effort alone and efforts should come from non-governmental organizations as well. Towards this, NeRuDO has been executing various socio-economic development projects including micro finance programs intended to benefit the disadvantaged and poor community, focusing on the women and children.

NeRuDO has been implementing the ‘grameen’ model microfinance program in accordance with Grameen Trust of Bangladesh. With due approval of concerned governmental agencies, NeRuDO started the Microfinance Program for rural poor women with seed fund of US$ 20,000 received from Grameen Trust, Bangladesh on December, 1998 as a loan. The program initiated from Manaharwa village of Bara district got good response from targeted communities which lead to expansion of the program to adjoining Parsa and Makwanpur districts so far.

Since its establishment, NeRuDO has been engaged in various development programs targeting the poorest section of the rural community of Nepal. NeRuDO is mainly focused in Bara, Parsa and Makwanpur districts of Terai, Chure and Bhabar regions. Now it is also expanding it's activities in mid-mountain region through it's newly opened branch office at Pharping in Kathmandu District - Capital of Nepal.The programs implemented and ongoing are Community Development Program (CDP), Health and Sanitation Education (HSE), Rural Drinking Water and Microfinance.