Other Bone Marrow Failure Syndromes

There are several other inherited
bone marrow syndromes
which are less common than the ones that are discussed individually
on this Website. These diagnoses are usually made by experts in
hematology or genetics. Examples include the following disorders:
IVIC (named with the initials of the institution which first reported
it), WT (after the initials of the first two families reported),
radio-ulnar synostosis (the bones of the lower arm are joined together
at the elbow), ataxia pancytopenia (unsteady walking and aplastic
anemia). There are families with more than one case with bone marrow
failure, who do not fit any of the usual categories. Finally, there
are other genetic diseases in which bone marrow failure has been
reported on rare occasions, but in which bone marrow failure is
not thought to be a major feature of the disease. These include
disorders such as Seckel syndrome, Dubowitz syndrome, and Down syndrome.