Summary

Name:

1392: Large Monomer Design: Smaller Core

Status:

Closed

Created:

06/16/2017

Points:

100

Expired:

06/23/2017 - 23:00

Difficulty:

Intermediate

Description:

This puzzle challenges players to design a single-chain protein with 85-105 residues. The Core Existence filter has been relaxed such that only 25% of residues need to be buried in the protein core. The starting structure has 85 residues, but more can be added at a cost of 23 points per residue. See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!