E2F transcription factors were originally identified as regulators of cell cycle and cellular proliferation. In vivo mouse models have uncovered novel roles for these proteins in different developmental processes. This ...

Economic globalization has resulted in the tremendous growth of worldwide trade. Much of this trade is carried out via the various waterways of the world. The bulk of these trade goods are transported by merchant ships ...

This thesis presents a novel optical technique, light scattering spectroscopy (LSS), developed for quantitative characterization of tissue morphology as well as in vivo detection and diagnosis of the diseases associated ...

Public and private organizations try to forecast the future of technological developments and allocate funds accordingly. Based on our interviews with experts from MIT's Entrepreneurship Center, Sloan School of Management, ...

Despite a number of human and robotic missions to the Moon, there are still important unanswered questions about its early evolution, and how it came to be the object we observe today. Here we use observational, experimental, ...

An analysis of the planning, development, and implementation of Oklahoma City's Grand Boulevard. In the early days of 1909, a plan emerged to build an expansive parks and boulevard system to encircle Oklahoma City. Such ...

Much of design research has been focused on developing prescriptive design processes, however, proper description of the designer, the object of design, and the context may be lacking (Dorst, 2007). The present research ...

What makes innovation happen in reality? The challenges companies have faced in building their competitive advantage have been shifting over the last decade, away from operational excellence and global footprint and towards ...

This thesis investigates the origin and evolution of large scale structure in the universe. We approach these questions from two different angles in two related but independent projects. The outcomes of these two investigations ...

High-technology Entrepreneurship has been a key driver of innovation and economic growth in the US. Aided by factors such as the success in IT and IT-enabled services industries and a booming economy, India has seen a sharp ...

CHAPTER 1. Zirconium and hafnium complexes of several new unsymmetric diamide ligands have been prepared and their proficiency in olefin polymerization reactions evaluated. The first set of supporting ligands examined are ...