2Department Of Cardiothoracic Surgery, Medical School, University of Patras, Patras/GR

3Department Of Pathology, Medical School, University of Patras, Patras/GR

4Department Of Anatomy, Medical School, University of Patras, Patras/GR

Abstract

BCL3 is an atypical member of the IκB family and it has been found to be overexpressed in hematological malignancies and in some solid tumors, playing a pivotal role in tumor initiation and progression. A tag single nucleotide polymorphism of BCL3 (SNP; rs8100239, T>A) has been identified recently but there are no data relating to its role in non-small cell lung cancer (NSCLC) development.