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Today, guest blogger Guigen Zhang, professor of bioengineering at Clemson University, talks about his new textbook on computational modeling for biomedical applications. This blog post discusses Integrative Engineering: A Computational Approach to Biomedical Problems, including its content and the intended readers; the purpose and motivation for writing this book; and most importantly, how getting an in-depth understanding of the “intricate machinery” of computational modeling will help make you a better modeler.