Regenerative Liver Technologies

The way we see it, the numbers in liver healthcare simply haven’t been adding up.

500

vital bodily functions performed by the liver organ

100

different types of disease that affect liver health + function

1

effective therapy to treat thousands in need of a life-saving transplant

Until now, organ transplant has been the one and only efficacious therapy to save hundreds of vital functions for thousands of lives. It is a successful procedure, but its availability is extremely limited.

Of the estimated 200,000 Americans with late-stage liver failure in need of a transplant each year, only 15,000 are lucky enough to make it on the waiting list.

A mere 6,000 of those will be matched with a donor in time to save their life. The other 97% of patients may die in waiting.

At HepaTx, we recognized this startling gap as an opportunity to do better.

Cell transplantation has proven to be an effective therapy to replace the lost regenerative capacity of a diseased liver, potentially restoring its vitality to that of a healthy organ.

Rather than wait for an unlikely replacement, why not regenerate cellular vitality in the organ that is already there? ﻿

So we developed a revolutionary new treatment.

A simple infusion of hepatocytes directly into the organ to replace dead and diseased liver cells.

Our proprietary SF-Heps is 3-part process licensed from Stanford and well protected by licensed IP. It provides an alternative to costly transplants and can be implemented across many liver diseases.

Cells can be manufactured, banked, and distributed for administration to patients as an allogeneic transplant.

We have proof of concept data showing that, in mouse models, cells transplanted this way have essential function as hepatocytes in vivo and are not tumorigenic.

To learn more about HepaTx and our regenerative medicine technologies,