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UFC 166 takes place Oct. 19 at Houston's Toyota Center. The main card, which features a heavyweight title fight and rubber match between champ Cain Velasquez and former titleholder Junior dos Santos, airs on pay-per-view following preliminary-card bouts on FOX Sports 1 and Facebook.

Boetsch, who had entered the title picture following four consecutive UFC wins in 2012, now finds himself in a must-win situation. The 32-year-old is stuck in a two-fight skid that includes a TKO loss to Constantinos Philippou and a recent decision loss to Mark Munoz. Prior to the setbacks, the former college wrestler was on an 8-1 run that included wins over notables such as Yushin Okami and Hector Lombard.

Rockhold, meanwhile, recently made his UFC debut following a title run in the since-shuttered Strikeforce promotion. However, in May's UFC on FX 8 headliner, he suffered a spinning-back-kick knockout loss to Vitor Belfort. The defeat snapped a nine-fight win streak that included victories over the likes of Ronaldo Souza, Keith Jardine and Tim Kennedy.