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After the events of Saints Row 2 the 3rd Street Saints have turned into a media empire, becoming a household name, with their own TV shows, energy drink, toys and planning on making a movie. The Boss, Shaundi and Gat prepare for the movie by robing a bank with Josh Birk, an actor who is to play a Saints' member, things don't go as planned after Josh trips an alarm and meet a lot of police resistance, after which the Saints end up in jail.