The winless Bills closed as 17-point underdogs coming into Week 3's contest the Vikings at Westgate Las Vegas SuperBook. However, Buffalo won Sunday's contest 27-6, marking the biggest upset of the NFL season so far.

In fact, the last time a 17-point underdog won an NFL game outright was in 1995 when the Cowboys lost at home to the Redskins as 17.5-point favorites.