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In a city so dismal it's known only as "the Hole," a clan of Sorcerers has been plucking people off the streets to use as guinea pigs for atrocious "experiments" in the black arts. In a dark alley, Nikaido found Caiman, a man with a reptile head and a bad case of amnesia. To undo the spell, they're hunting and killing the Sorcerers in the Hole, hoping that eventually they'll kill the right one. But when En, the head Sorcerer, gets word of a lizard-man slaughtering his people, he sends a crew of "cleaners" into the Hole, igniting a war between two worlds.

All mysteries lead back to the Hole! Our labyrinthine tale is nearing its end, but it’s not over quite yet. Caiman and Nikaido, Risu and the En family, and all of the embattled characters who made a miraculous recovery in our previous volume gear up fight the Cross-Eyes’ boss in a no-holds-barred battle royale! This is going to be full-throttle mayhem!

Known for her bold style and seamless creation of alternate universes, Q. Hayashida made her manga debut with Maken X Another, which ran in Magazine Z and was subsequently adapted into a video game. She followed this series with a sequel, Maken X Another Jack. Dorohedoro is her latest series.