Should not use in over dosage. Patients with mild to moderate renal failure. Diabetes, patients prone to recurrent renal calculi.

Drug Side Effects ::

Generally well tolerated.

Pregnancy category ::

0

Drug Mode of Action ::

Calcium carbonate/vitamin D3 prevents or treats negative Ca balance. It also helps facilitate nerve and muscle performance as well as normal cardiac function. Bone mineral component; cofoactor in enzymatic reactions, essential for neurotransmission, muscle contraction, and many signal transduction pathways. Vitamins and minerals are essential for normal metabolic functions including hematopoiesis. Vitamin D3 is a fat-soluble sterol. It is necessary for the regulation and regulation of calcium and phosphate homoeostasis and bone mineralisation. Vitamin D is also essential for healthy bones as it aids in Calcium absorption from the GI tract. Vitamin C is necessary for collagen formation and tissue repair; plays a role in oxidation/reduction reactions as well as other metabolic pathways including synthesis of catecholamines, carnitine, and steroids; also plays a role in conversion of folic acid to folinic acid. Vitamin E plays a role in protecting red blood cells against hemolysis; has protective effects against free radicals on polyunsaturated fatty acids found in cell membranes; plays a role in preventing oxidation of vitamin A and C. Zinc is a cofactor in over 100 enzymes; plays a role in DNA synthesis; supports a healthy immune system. Copper cofactor in many enzymes, including ceruloplasmin; involved in formation of iron carrier protein, transferrin. Helps maintain normal rates of red and white blood cell formation and helps prevent development of deficiency symptoms. Magnesium acts as cofactor in numerous enzymatic reactions involving protein synthesis and carbohydrate metabolism; depresses CNS, blocks peripheral neuromuscular transmission, produces anticonvulsant effects.

Drug Interactions ::

0

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