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The information provided here is meant to give you a general idea about each of the medications listed below. Only the most general side effects are included, so ask your doctor if you need to take any special precautions. Use each of these medications as recommended by your doctor, or according to the instructions provided. If you have further questions about usage or side effects, contact your doctor.

Medications for obesity should not be used alone. Rather, they should be part of a comprehensive weight loss program that includes:

Taken at a dose of 120 milligrams 3 times a day, Xenical prevents ingested fat from being absorbed by blocking digestive enzymes. About 30% of the fat you eat will remain in your bowels. In some, the fat is excreted by the body between bowel movements as an oily discharge.
It is recommended for long-term use (up to about 2 years). Orlistat is also available in a 60-mg over-the-counter form, called Alli.

Possible side effects include:

Staining of underwear

Gas

Pressure to empty bowels

Leakage of stool

Increased frequency of bowel movements

Severe liver damage (rarely)

Over-the-Counter (OTC) Medications

OTC medications advertised as promoting weight loss are generally considered ineffective.
Some have led to serious side effects. Do not use over-the-counter or herbal remedies without talking to your doctor.

Special Considerations

If you are taking medications, follow these general guidelines:

Take the medication as directed. Do not change the amount or the schedule.

Ask what side effects could occur. Report them to your doctor.

Talk to your doctor before you stop taking any prescription medication.

Plan ahead for refills if you need them.

Do not share your prescription medication with anyone.

Medications can be dangerous when mixed. Talk to your doctor if you are taking more than one medication, including over-the-counter products and supplements.

Revision Information

This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.

Prescription medications for the tretment of obesity. National Institute of Diabetes and Digestive and Kidney Diseases. Available at:
http://www.niddk.nih.gov/health-information/health-communication-programs/win/win-health-topics/Pages/default.aspx#meds. Accessed August 28, 2012.