Not sure about Reaper, but there is Pitch Shift option in Nuendo where you can fine tune the frequency in cents. Melodyne plugin also has a good fine-tune function.As for MIDI, it depends on the VST instrument itself if it can transpose like that. Perhaps if it is some kind of oscilator with clear labeled frequencies, but I rarely saw those.

Not sure about Reaper, but there is Pitch Shift option in Nuendo where you can fine tune the frequency in cents. Melodyne plugin also has a good fine-tune function.As for MIDI, it depends on the VST instrument itself if it can transpose like that. Perhaps if it is some kind of oscilator with clear labeled frequencies, but I rarely saw those.

Thanks a lot for your answer Ivan, I found the way to tunethe freq. in cents in REASON with the master tuner in the preferences , so what I'm doing is that Im rewiring the Reason to Reaper, and it's working fine.

Thanks again, I really appreciate that you took the time to answer this awkard post.