New Approaches to Antibiotic Therapy for Acute Tonsillopharyngitis in Children

Yu.K. Bolbot

Abstract

In recent years, a trend for reduced efficacy of treatment for acute tonsillopharyngitis with antibiotics of peni­cillin group in children has been observed. This is due to the changes in the etiology of the disease: in the genesis of acute tonsillopharyngitis, associations of β-hemolytic streptococcus with Gram-negative and Gram-positive microflora are involved. The use of II generation cephalosporins significantly improves the efficacy of therapy and reduces the risk of complications.

Gerber M.A., Baltimore R.S., Eaton C.B. et al. Prevention of Rheumatic Fever and Diagnosis and Treatment of Acute Streptococcal Pharyngitis: A Scientific Statement From the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: Endorsed by the American Academy of Pediatrics // Circulation. — 2009. — Vol. 119. — Р. 1541-1551.