Legendary boxer Muhammad Ali, arguably the greatest boxer of all-time, died Friday in Phoenix, Arizona at age 74.

Bob Gunnell, a spokesperson for the family said Ali had be hospitalized since Thursday dealing with respiratory issues.

Ali, known for his activism as well as his athletic prowess, was hospitalized in January 2015 for a urinary tract infection and suffered from pneumonia in December 2014.

Born as Cassius Clay, Ali is an Olympic gold medalist and was once the World Heavyweight Champion. In 1964, Ali converted to Islam and changed his name. The 74-year-old lost his title after refusing to enlist in the Vietnam War.

Former president George W. Bush presented Ali with the Presidential Medal of Freedom in 2005.

Muhammad Ali is seen training October 9, 1974 for his world championship fight in Zaire. (AP Photo)

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