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Subject: About PATH's work > Advancing technologies

DefeatDD.org is an interactive website aimed at informing and inspiring advocates committed to joining their voices and raising awareness about diarrheal disease. The website hosts a weekly blog about advances in diarrheal disease control and provides key documents and links to information on simple, lifesaving interventions that have the potential to significantly impact diarrhea incidence worldwide.

PATH collaborates with the US Department of Defense (DoD) to advance global health innovations. This fact sheet provides examples of successes that PATH, DoD, and our partners have had in working to adapt, test, and expand access to tools and technologies that can reduce illness in the world’s most vulnerable populations.

This brochure outlines PATH's work in China, with emphasis on public-private partnerships for product development. Areas of focus include vaccines and immunization, health technologies, and women's health.

Artemisinin-based combination therapy is considered the gold standard treatment for malaria, but global demand has often outpaced production, and pricing has been volatile. This fact sheet describes the cross-sector partnership PATH formed to develop a new way to produce high-quality, nonseasonal, and affordable artemisinin to supplement the plant-based supply.

Part of the Technology Updates series, this fact sheet describes PATH’s work to address the problem of vaccines freezing during transport by incorporating a freeze-safe inner vaccine box into vaccine carriers.

In 2013, PATH and our partners touched the lives of more than 219 million people with new vaccines and drug treatments, breakthrough health tools, and powerful strategies to change the course of disease. Our 2013 annual report highlights our achievements across five innovation platforms.

Part of the Technology Updates series, this fact sheet describes PATH's work to develop, test, and introduce a low-cost balloon tamponade that can be used in low-resource settings to control postpartum hemorrhage.

Part of the Technology Updates series, this fact sheet describes PATH's work to develop and evaluate the concept of ready-to-use magnesium sulfate (MgSO4) packs that will eliminate dosing calculation and dilution at the time of use.

This project brief describes PATH’s work in promoting tuberculosis (TB) control in India by contributing to health human resources development throughout the country. With support from the United States Agency for International Development, PATH worked with Initiatives Inc. to assess the state of human resources working in TB-related capacities in India, to analyze the feasibility of integrating the national TB program with the general health system, and to pilot an integrated model of TB programming within the general health system in four districts. The brief outlines lessons learned that can be applied to future health human resources development in TB-related capacities in India and globally.

Part of the Technology Updates series, this fact sheet describes PATH's work to develop an oxytocin sublingual fast-dissolving tablet presentation that dissolves in less than ten seconds in the patient’s mouth without the need for additional water or diluent. Oxytocin in this type of presentation could potentially increase the reach and efficacy of this lifesaving medication to areas lacking access to skilled health workers, refrigeration, or safe injection equipment.

This project brief outlines PATH’s work in strengthening national laboratories in India to correctly diagnose tuberculosis (TB), including multidrug-resistant tuberculosis (MDR-TB). In collaboration with FIND, the World Health Organization, and other partners, PATH provided intense technical assistance to India's Revised National TB Control Program to introduce new diagnostic technologies into Indian laboratories, improve biosafety and infrastructure, build nationwide laboratory networks, and strengthen quality assurance. This work was made possible through support from the United States Agency for International Development.

Part of the Technology Updates series, this fact sheet describes PATH's work in adapting the concept of a dilution bottle to simplify the process of magnesium sulfate administration for the treatment of preeclampsia and eclampsia. A dilution bottle bottle can facilitate the safe calculation of recommended doses by obviating the need to remember complex equations for dilution.

Part of the Technology Updates series, this fact sheet describes PATH’s work in collaboration with the University of Washington to develop a mobile application for magnesium sulfate administration for the treatment of preeclampsia and eclampsia. The application includes a dosing calculator and a detailed checklist based on World Health Organization protocol and is designed specifically to address the challenges of correctly calculating the dosage.

This project brief describes one aspect of PATH’s contributions to tuberculosis (TB) control in India. With the support of the United States Agency for International Development, PATH worked with India’s Revised National TB Control Program to implement new national guidelines on airborne infection control in India. Work included developing education materials for health workers and their patients, convening experience-sharing workshops for national TB program staff, and training local engineers and architects to design effective infection-control measures within health facilities.

This project brief describes PATH’s contributions to developing public-private mix (PPM) approaches to TB control in India. With support from the United States Agency for International Development, PATH supported a PPM pilot project in Andhra Pradesh that aimed to train private chemists in identifying presumed TB cases and referring them to government diagnosis centers, promoting community awareness of TB prevention, and reducing the sale of TB drugs to persons without a prescription. This project provided valuable lessons and insights into applying PPM strategies to future TB control projects in India and elsewhere.

Part of the Technology Updates series, this fact sheet describes PATH's work to develop a rectally administered magnesium sulfate (MgSO4) formulation that could simplify delivery and improve access to MgSO4 treatment in low-resource settings.

Severe preeclampsia and eclampsia (PE/E) are among the leading causes of maternal death and disability worldwide. Magnesium sulfate is the treatment recommended by the World Health Organization, but it remains underutilized due to difficult administration. PATH designed a mobile application for dosing and dilution of magnesium sulfate to address the challenges of correctly calculating magnesium sulfate dosage given multiple concentrations and a complex dosing regimen.

With funding from the Canadian International Development Agency, PATH is working to address the information gap on how to best tailor and scale up proven HIV prevention strategies among at-risk populations through cost-effective interventions in India, Senegal, Uganda, Zambia, and Zimbabwe.

Part of the Technology Updates series, this fact sheet describes PATH and our partners’ work to validate a new web-based cold chain equipment inventory (CCEI) tool, which is a module of the DHIS2 open-source software platform. This tool will provide opportunities for countries to integrate CCEI data into their national health management information systems. Find out more about PATH's work in digital health solutions.