When lowering or raising compression, you will see around a 3% loss or gain in power for about 1 compression ratio. This isn't perfect math, but it's simply.

When raising boost, you tend to see about a 3% per 2 psi.

If you take a motor and lower its compression from say, 12.5:1 to 10.5:1 giving it approximately a 6% loss in power. Now let's say we add 10 psi, giving it an approximate 15% increase. We've netted an overall change of 9%.

The reason for all this is, even though you are compressing it, N/A does not allow for more air than atmospheric, (Also why cars have less power at higher altitudes) whereas a turbo will cram air in there causing it to have more oxygen per square inch, or more fuel to burn with the gasoline.

I hope this makes sense.

Oh and as for why to not lower your compression ratio. If you have a low compression ratio, your non boosted power is substantially less. (Like you have lost that 6% earlier, but with no gain) so you tend to notice lag more and it is less effective for racing which requires you dip lower into RPM ranges. (I.E. road courses etc.)