The detailed view includes drug products with safety labeling changes to the BOXED WARNING, CONTRAINDICATIONS, WARNINGS, PRECAUTIONS, ADVERSE REACTIONS, or PATIENT PACKAGE INSERT/MEDICATION GUIDE sections. Deletions or editorial revisions made to these sections are not included in this summary. Read about the new physician labeling format.

Hypercalcemia has been reported in a patient with hyperthyroid disease at therapeutic theophylline concentrations.

“Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia.

CONTRAINDICATIONS

Solutions containing dextrose may be contraindicated in patients with known allergy to corn or corn products

WARNINGS

When Signs and Symptoms of Theophylline Toxicity are Present

“Solutions containing dextrose without electrolytes should not be administered simultaneously with blood through the same infusion set... ...Because dosages of these drugs are titrated to response, no additives should be made to Theophylline in 5% Dextrose Injection USP."