*Department of Anesthesiology, University of Colorado, Aurora; †Division of Substance Dependence, Department of Psychiatry, University of Colorado, Aurora; ‡Department of Neurology, University of Colorado, Aurora; §Department of Pediatrics, University of Colorado Anschutz Medical Campus, Children's Hospital Colorado, Aurora; ¶Department of Epidemiology, Colorado School of Public Health, University of Colorado, Aurora; and ‖Division of Pulmonary Medicine, National Jewish Health, Denver, Colorado.