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October 2017 • The PCB Design Magazine 35
5. Polar Instruments Si9000e Version 2017.
6. Keysight Advanced Design System (ADS)
Version 2016.
7. Park Electrochemical Corp. Nelco Digital
Electronic Materials.
8. Oak-Mitsui.
Bert Simonovich is the founder
of Lamsim Enterprises, where he
provides innovative signal integrity
and backplane solutions to clients.
His current research interests in-
clude signal integrity, high-speed
characterization, and modeling of
high-speed serial links associated with backplane
interconnects. To contact him or read past col-
umns, click here.
good answer later, then this method might be
right for you.
PCBDESIGN
References
1. Bert Simonovich, "A Practical Method to
Model Effective Permittivity and Phase Delay Due
to Conductor Surface Roughness," DesignCon
2017 Proceedings, Santa Clara, California, 2017.
2. Bert Simonovich, "Practical Model of
Conductor Surface Roughness Using Cubic
Close-packing of Equal Spheres," EDICon 2016,
Boston, Massachusetts.
3. Hammerstad, E.; Jensen, O., "Accurate
Models for Microstrip Computer-Aided Design,"
Microwave Symposium Digest, 1980 IEEE MTT-
S International, pp.407,409, 28-30 May 1980
doi: 10.1109/MWSYM.1980.1124303.
4. Huray, P. G. (2009) "The Foundations of
Signal Integrity," John Wiley & Sons Inc., Hobo-
ken, NJ, USA., 2009.
PRACTICAL MODELING OF HIGH-SPEED BACKPLANE CHANNELS
Research being done at Rochester Institute of
Technology to refine lab-on-chip devices will pro-
vide more detailed and timely information to de-
tect diseases such as cancer.
Blanca Lapizco-Encinas, a faculty-researcher in
RIT's
Kate Gleason College of Engineering, is im-
proving the process of separating biological cells
and biomolecules using chromatography prin-
ciples, a well-established technique for separating
proteins, combined with a newer technique called
dielectrophoresis, a process that uses electrical cur-
rent to separate biomolecules.
In biomedical analysis, clinicians may have to
analyze complex blood samples consisting of cells,
proteins
and
other micron-sized particles, in an
effort to separate healthy and diseased cells. Im-
proved microfluidic techniques
with the
potential to separate
cells found in bio-fluids, are use-
ful in settings where rapid results
are essential such as testing for
food and water safety
or clinical
analysis of disease.
"You put into a device a sample with six or sev-
en different types of particles and you can separate
them, in
some cases in less than two minutes, just
by applying electric fields," Lapizco-Encinas ex-
plained.
The new research, utilizing electroosmotic flow
is expected to drive particles across the micro-
channel. This process of electroosmotic flow offers
the potential for the biomolecules to be manipu-
lated in real-time, allowing for dynamic separation
schemes. This work expands Lapizco-Encinas' pre-
vious research
that focused on the development of
multi-channel devices where fluid samples are as-
sessed after being exposed to electrical currents that
cause the bio-particles to separate for more efficient
analysis. Through past
research,
she and her team
advanced device system designs and
determined an optimal threshold of
electrical fields applied to adequately
manipulate the fluids and ensure that
live cells are not damaged. Adding
chromatographic principles to this
foundational work is underway.
Hybrid Biological Cell Separations Technology
for Lab-On-Chip Medical Devices