What Predsolone is used for

Predsolone contains prednisolone as the active ingredient. Prednisolone belongs to a group of medicines called corticosteroids which are a synthetic version of a naturally occurring body hormone called cortisol.

Predsolone works by entering inflammatory cells and blocking the inflammatory reaction. This medicine is only able to prevent or reduce symptoms of your condition, it does not cure it.

Predsolone is used in the treatment of many different conditions. Some of these conditions include: severe allergies, severe or chronic asthma, skin problems, arthritis, inflammatory diseases of the bowel, cancer and "auto-immune" diseases.

It is also used to prevent or reduce the symptoms of inflammation (such as swelling, redness, pain, tenderness or itching) in any part of the body. These symptoms can occur in response to injury or can be caused by many different conditions.

Ask your doctor if you have any questions about why Predsolone has been prescribed for you.

Before you take it

When you must not take it

Do not take Predsolone if you have ever had an allergic reaction to:

prednisolone or prednisone

any of the ingredients listed at the end of this leaflet.

Symptoms of an allergic reaction may include shortness of breath, wheezing or difficulty in breathing; swelling of the face, lips, tongue or any other parts of the body; rash, itching or hives on the skin.

Do not take it if you have a current serious or uncontrolled infection, including fungal infections.

Do not take Predsolone after the expiry date (EXP) printed on the bottle.

It may have no effect at all or an entirely unexpected effect if you take it after the expiry date.

Do not take it if the bottle shows signs of having been tampered with.

Do not take this medicine to treat any other complaints unless your doctor has instructed you to do so.

Do not give this medicine to anyone else.

Before you start to take it

Tell your doctor if you are allergic to any other medicines or any foods, dyes or preservatives.

Tell your doctor if you have or have had any of the following medical conditions:

a current serious or uncontrolled infection, including fungal infections

recent surgery or serious injury

diabetes mellitus (sugar diabetes)

osteoporosis (softening of the bone)

a stomach ulcer or other stomach or intestinal problems

liver, kidney or heart disease

tuberculosis

epilepsy

muscle weakness

glaucoma (high pressure in the eye) or cataracts

thyroid disease

high blood pressure.

Do not take Predsolone if you are pregnant or plan to become pregnant.

It is not generally recommended for use in pregnant women unless the benefits of treatment outweigh the risk to the unborn baby.

Do not take it if you are breast feeding or plan to breast feed.

It is not recommended for use while breast feeding as it is found in breast milk.

If you have not told your doctor about any of these things, tell them before you take Predsolone.

Taking other medicines

Tell your doctor or pharmacist if you are taking any other medicines, including any that you get without a prescription from a pharmacy, supermarket or health food shop.

Some medicines may interfere with Predsolone. These include:

antacids (in large amounts)

medicines for diabetes

some medicines for heart disease

medicines for removal of fluid (diuretics)

some medicines for epilepsy

some types of antibiotics

potassium or salt supplements

immunisations or vaccines.

These medicines may be affected by Predsolone or may affect how well it works. You may need to take different amounts of your medicine or you may need to take different medicines. Your doctor or pharmacist has a more complete list of medicines to be careful with or avoid while taking Predsolone.

Use in children

Take special care when giving Predsolone to children. It should only be given under your doctor's supervision.

If possible, children should not be exposed to common childhood illnesses such as chickenpox or measles while they are taking Predsolone. They may suffer from more serious attacks of these illnesses if such exposure occurs.

Children should not be vaccinated with "live" vaccines against common childhood illnesses while they are taking it, as this may result in severe attacks of these illnesses.

Potentially serious side effects can occur in children and growing teenagers who are taking corticosteroids. Some of these include obesity, slowed growth, osteoporosis (softening of the bone), and changes to the adrenal glands.

Use in elderly

Elderly patients may be more sensitive to the effects or side effects of this medicine.

How to take it

How much to take

The dose will depend on the condition being treated and your response to the treatment. Your initial dose will be maintained or adjusted until a satisfactory response is noted.

How to take it

Swallow the tablet whole with a glass of water.

When to take it

Predsolone is best taken with or immediately after food.

How often Predsolone can be taken may vary depending on what condition is being treated. It can be taken once daily, several times a day or on alternate days (every other day).

If you take it once a day or every second day, then it it best taken at breakfast time. If it needs to be taken more than once a day, then space it out during the day.

How long to take it

Continue taking Predsolone for as long as your doctor tells you.

This will depend on your condition and on your response to treatment. Some people will need this medicine for only short periods of time whilst others may require long term therapy.

Do not miss any doses and do not stop taking the medicine even if you feel better.

Missing doses may make your symptoms worse.

What to expect

Individuals will vary greatly in their response to Predsolone. Your doctor will check your progress at regular intervals.

If you forget to take it

If you miss a dose of this medicine the decision of whether you should take it or not will depend on how many times a day you take Predsolone.

If you are taking Predsolone:

once a day-If you miss a dose and remember in less than 12 hours, take it straight away, then continue as normal the next day. Otherwise, skip that day's dose but be sure to take the next day's dose when it is due.

several times a day-If you miss a dose and it is more than 2 hours before your next dose is due, take it straight away and then continue as you normally would.If it is less than 2 hours to your next dose, skip the dose you have missed but be sure to take the next dose when you are meant to.

on alternate days-If you miss a dose and remember it the same morning, take it straight away then continue as you normally would. If you do not remember the missed dose until later, wait and take it the following morning. Then skip a day before continuing your regular dosage schedule.

Do not try to make up for missed doses by taking more than one dose at a time.

If you have trouble remembering when to take your medicine, ask your pharmacist for some hints.

If you take too much (overdose)

Immediately telephone your doctor or Poisons Information Centre (telephone 13 11 26) for advice, or go to Accident and Emergency at your nearest hospital if you think that you or anyone else may have taken too much Predsolone. Do this even if there are no signs of discomfort or poisoning.

While you are taking it

Things you must do

If you do not follow your doctor's instructions you may not get improvement in the symptoms of your condition. Try not to miss any doses and take the medicine even if you feel well.

Tell your doctor if your condition returns or becomes worse after your dose of Predsolone has been reduced or treatment has been stopped.

Tell your doctor immediately if you become pregnant while taking Predsolone.

Tell any other doctors, dentists and pharmacists who are treating you that you are taking Predsolone, especially if you are being started on any new medicines.

Tell your doctor, surgeon or dentist that you are taking Predsolone if you are about to undergo surgery or an operation.

Your dose of this medicine may need to be increased to cover you during the stress of the operation.

Tell your doctor straight away if you are a diabetic, and you notice a change in the results of your blood or urine sugar tests.

This medicine may affect your blood sugar levels as it can affect the body's ability to handle glucose. For diabetics, this means that your diabetes may become more severe. For others, diabetes may develop for the first time while taking corticosteroids such as Predsolone.

Ask your doctor when and how you should stop taking Predsolone.

If you have been taking it for a long time your doctor may gradually reduce the amount you are taking over a period of several days, weeks or months before stopping completely.

If you have been taking Predsolone for a short period of time, this may not apply.

Things you must not do

Do not give this medicine to anyone else even if their symptoms seem similar to yours.

Do not stop taking Predsolone suddenly unless advised by your doctor.

If you stop taking it suddenly, the symptoms of your condition may return or you may develop symptoms of cortisol deficiency such as fainting, weakness, restlessness, nausea, vomiting, headache, dizziness, muscle weakness or joint pain.

Do not have any immunisations (particularly with "live" vaccines such as measles, oral polio or yellow fever) without your doctor's approval while you are being treated with Predsolone.

Things to be careful of

Avoid close contact with anyone who has a contagious disease such as measles or chickenpox.

Exposure to such diseases while you are taking this medicine, particularly if large doses are being taken, can put you at greater risk of developing these diseases if you have not had them before.

Tell your doctor straight away if you think you have been exposed to chickenpox or measles.

Things to be aware of

As with any new medicine, you should take care when driving or operating machinery until you know how Predsolone affects you.

Check with your doctor or pharmacist before drinking alcohol while you are taking this medicine.

If you drink alcohol while taking it you may find that stomach problems occur.

The signs and symptoms of infections such as fever or inflammation may be hidden by the anti-inflammatory action of Predsolone. You should see your doctor for medical advice for any but the most minor infections.

Side effects

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Predsolone.

Predsolone helps most people who take it, but it may have unwanted side effects in some people. All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.

Ask your doctor or pharmacist to answer any questions you may have.

Short term use

When Predsolone is taken for short periods of time it is unlikely to cause any problems.

Tell your doctor if you notice any of the following side effects and they worry you:

mood changes

nausea (feeling sick)

vomiting

anorexia (which may result in weight loss)

increased appetite (which may result in weight gain)

stomach bloating or irritation

diarrhoea or constipation.

Long term use

When Predsolone is taken for long periods of time and in high doses the risk of side effects is greater.

Tell your doctor if you notice any of the following and they worry you:

general changes to the body:

bloating and rounding of the face (moon face)

headache

dizziness

weight gain

redistribution of body fat

water retention leading to swollen legs and feet, high blood pressure or an irregular heart beat

cramps or weakness in the muscles of the arms and legs

slowed growth in children

irregular menstrual periods.

changes to the skin:

acne

red or flushed face

extra hair growth

red or purple streaks

easy bruising

skin thinning

increased sweating

poor wound healing.

changes to the immune system:

an increased seriousness or frequency of infections.

changes in behaviour:

excessive mood swings (such as changes in personality)

anxiety or nervousness

restlessness

trouble sleeping.

changes in eyes:

decreased or blurred vision

eyes sticking out too far

cataracts.

Tell your doctor immediately or go to Accident and Emergency at your nearest hospital if you notice any of the following symptoms:

Related information - Predsolone Tablets

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04 Sep2013 –
Information on medicines available in Australia containing prednisolone (corticosteroids (oral and injectable)), including our latest evidence-based information and resources for health professionals and consumers. The active ingredient is the chemical in a medicine that makes it work. Medicines that contain the same active ingredient can be available under more than one brand name. Brands include both active ingredients and inactive ingredients. You'll find information about brands of medicines that contain prednisolone (corticosteroids (oral and injectable)) below, including their consumer medicine information (CMI) leaflets.

Brand information

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What is a consumer medicine information (CMI) leaflet?

A consumer medicine information (CMI) leaflet tells you about the side effects of a particular medicine, what it is used for and how to use it, and is written according to Australian government standards.

Reasonable care is taken to provide accurate information at the time of creation. This information is not intended as a substitute for medical advice and should not be exclusively relied on to manage or diagnose a medical condition. NPS MedicineWise disclaims all liability (including for negligence) for any loss, damage or injury resulting from reliance on or use of this information. Read our full disclaimer.