If your thinking a Western Style RPG like the Elder Scrolls series, not really. There are two Monster Hunter games for 3DS, one is a remake of Tri that hasn't been announced for localization yet, and then Monster Hunter 4 which hasn't released anywhere yet. Zelda Ocarina of Time has a open world that was revolutionary for the time and some RPG like elements, but you likely know whether you like Zelda or not at this point. You could also look into Tales of the Abyss, which is an action RPG that allows you to explore a very large world, and may be to your liking.