In March 1990, she had a very severe accident on her tour bus. Gloria made her comeback in March 1991 with a new world tour and album called Into The Light. She became an inspiration to all. In 1993 she won her first Grammy Award for Best Tropical Latin Album. It was the first number-one album on the Billboard Top Latin Albums chart, established when it was released. It was also the first Diamond album in Spain. Many of her songs like Rhythm Is Gonna Get You, 1-2-3, Get On Your Feet, Here We Are, Coming Out of the Dark, Bad Boy, Oye!, Party Time and a remake of Vicki Sue Robinson's Turn the Beat Around became international hits, with chart-topping scores. Estefan is one of the world's best-selling music artists of all time, with an estimated 100 million records sold worldwide, including 31.5 million in the United States alone.

She has won a total of seven Grammy Awards. Gloria also received a star on the Hollywood Walk of Fame and Las Vegas Walk of Fame and The Ellis Island Congressional Medal of Honor, which is the highest award that can be given to a naturalized U.S. citizen. Estefan also won the Hispanic Heritage Award, an MTV Video Music Award, two ACE Awards and the National Music Foundation's Humanitarian of the Year Award. She was also honored with the American Music Award for Lifetime Achievement as well as being named BMI Songwriter of the Year. She was inducted into the Songwriters Hall of Fame and has received multiple Billboard Awards for her many chart-topping hits.She is also on the list of Vh1 top 100 Greatest Artists of All Time and one of the Top 50 female Artists Who Will Never Be Forgotten, according to The Sun tabloid, UK. In 2015 she was added to the list of Now It Counts as one of The Most Powerful Americans and in Billboard's Top 30 Most Influential Latin Artists Of All Time.