Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst upgrade.

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

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Alexza Pharmaceuticals ( ALXA) is a pharmaceutical company focused on the research, development, and commercialization of products for the acute treatment of central nervous system conditions. This stock is trading up 14.86% to $4.56 in recent trading.

Today's Range: $4.28-$4.99

52-Week Range: $2.55-$19.10

Volume: 2.7 million

Three-Month Average Volume: 216,325

Shares of ALXA are soaring today after the company said it has resubmitted its application for Adasuve, which is a schizophrenic and bipolar disorder treatment.

From a technical perspective, ALXA is gapping up big here back above its 50-day moving average of $4.39 with monster volume. This move is following a large gap-up on Friday that also occurred with monster volume.

Traders should now look for long-biased trades once ALXA takes out today's high of $4.99 with high-volume. Look for a sustained move or close above $4.99 with volume that's near or above 216,325 shares. If we get that action soon, then ALXA could fill a previous gap-down in price from back in May that took the stock from $6 to under $4. A high-volume move above $4.99 could mean we see $6 or possibly even $7.60.

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Senomyx (SNMX) is focused on using taste receptor technologies to discover and develop flavor ingredients for the packaged food, beverage and ingredient supply industries. This stock is trading up 8.5% to $2.28 in recent trading.

From a technical perspective, SNMX is ripping higher here back above its 50-day moving average of $2.25 with light volume. This move is quickly pushing SNMX within range of triggering a near-term breakout trade . That trade will hit once SNMX takes out some near-term overhead resistance levels at $2.28 to $2.40 with high volume. At last check, SNMX has hit an intraday high of $2.32 with volume that's well below its three-month average action.

Traders should now look for long-biased trades once SNMX sustains a move or close above those levels with volume that's near or above 222,228 shares. If we get that action soon, then SNMX could re-test and possibly take out its next significant overhead resistance levels at $2.60 to $2.69 in the near future.

Ocean Power Technologies

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Ocean Power Technologies ( OPTT) develops and is commercializing systems that generate electricity by harnessing the renewable energy of ocean waves. This stock is trading up 9.4% at $2.18 in recent trading.

Today's Range: $1.99-$2.20

52-Week Range: $2-$5.60

Volume: 58,000

Three-Month Average Volume: 32,477

From a technical perspective, OPTT is bouncing here off some previous support levels at around $2 with above average volume. This move is quickly pushing the stock within range of triggering a near-term breakout trade. That trade will hit once OPTT takes out some near-term overhead resistance at $2.28, and then its 50-day moving average of $2.32 with high volume.

Traders should now look for long-biased trades if OPTT can sustain a move or close above those levels with volume that's near or above 32,477 shares. If we get that action soon, then OPTT could easily re-test its next significant overhead resistance levels at $2.80 to $2.99 in the near future.

School Specialty

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School Specialty ( SCHS) is an education company serving the pre-kindergarten through twelfth grade market with instructional solutions that address a range of educational needs, from basic school supplies to standards-based curriculum solutions. This stock is trading up 6.8% at $3.12 in recent trading.

Today's Range: $2.93-$3.22

52-Week Range: $2.15-$15.84

Volume: 150,000

Three-Month Average Volume: 219,244

From a technical perspective, SCHS is ripping higher here with decent volume right off its 50-day moving average of $2.90. This move is quickly pushing the stock within range of triggering a near-term breakout trade. That trade will hit once SCHS takes out some near-term overhead resistance levels at $3.23 to $3.38 with high volume.

Traders should now look for long-biased trades once SCHS sustains a move or close above those levels with volume that's near or above 219,244 shares. If we get that action soon, then look for SCHS to continue its uptrend and possibly hit its March high of $4.03 in the near future. Traders should key off of its 50-day moving average of $2.90 for near-term support.

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ValueVision Media ( VVTV) is an interactive retailer that markets, sells and distributes products to consumers through television, telephone, online, mobile and social media. This stock is trading up 7.9% at $2.18 in recent trading.

From a technical perspective, VVTV is soaring here with decent volume right off its 200-day moving average of $2.04. This move has VVTV flirting with a major breakout trade, since the stock has started to move above some major near-term overhead resistance at $2.16. This move is also following a massive spike in upside volume on Friday after 5.81 million shares traded.

Traders should now look for long-biased trades as long as VVTV is trending above both its 200-day and that key resistance level of $2.16 with strong upside volume flows. I would consider any upside volume day that registers near or above 321,383 shares as bullish. If we continue to see that action, then VVTV should easily re-test and possibly take out its next significant overhead resistance level at $2.59 in the near future.

Supernus Pharmaceuticals

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Supernus Pharmaceuticals ( SUPN) is a specialty pharmaceutical company focused on developing and commercializing products for the treatment of central nervous system diseases, including neurological and psychiatric disorders. This stock is trading up 9.9% to $5.66 in recent trading.

Today's Range: $5.15-$5.74

52-Week Range: $4.30-$7.01

Volume: 53,000

Three-Month Average Volume: 67,079

From a technical perspective, shares of SUPN are soaring here with decent volume, and the stock has started to enter breakout territory with shares moving above some near-term overhead resistance at $5.45.

Traders should now look for long-biased trades as long as SUPN is trending above $5.45 with strong upside volume flows. I would consider any upside volume day that registers near or above 67,079 shares as bullish. If we continue to see that action, then look for SUPN to re-test and possibly take out its next significant overheard resistance levels at $6.10 to $6.50 in the near future. If we get that action, and $6.50 gets taken out with volume, then look for even more upside once SUPN takes out its all-time high of $7.

Lee Enterprises

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Lee Enterprises ( LEE) provides local news, information and advertising in midsize markets, with 49 daily newspapers and a joint interest in four others, nearly 300 weekly newspapers and specialty publications in 23 states. This stock is trading up 11% at $1.59 in recent trading.

Today's Range: $1.42-$1.70

52-Week Range: $0.49-$1.73

Volume: 1.4 million

Three-Month Average Volume: 314,892

From a technical perspective, LEE is skyrocketing here with monster volume. This move has started to push LEE into breakout territory since the stock has moved above some major overhead resistance at $1.54 to $1.56 with heavy volume.

Traders should now look for long-biased trades once the next major breakout trade triggers for LEE. That trade will hit once LEE takes out some past overheard resistance at $1.73 with high-volume. At last check, LEE has hit an intraday high of $1.70 today and volume is well above its three-month average action. Look for a sustained move or close above $1.70 with volume that's near or above 314,892 shares. If we get that action soon, then LEE could re-test and possibly take out its next significant overhead resistance levels at $2.24 to $2.75 in the near future.

At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Windermere, Fla., is an independent trader who focuses on stocks, options, futures, commodities and currencies. He is also an outside contributor to Beconequity.com and maintains the website Maddmoney.net, which he sold to Blue Wave Advisors in 2008. Roberto studied International Business at The Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany.

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