Research & Development

The core elements of the Scannexus facility are three Ultra-High-Field whole-body MRI scanners, supplied by Siemens; a 3T Magnetom Prisma Fit, a 7T Magnetom and a 9.4T Magnetom.

Ultra-High-Field imaging provides new levels of insights into anatomy and function, opening up a range of possibilities with implications for medical diagnosis and treatment.

AnatomyThe potential to improve spatial resolution to a range of 100-200µm will enable visualisation of (for example) different layers of the cerebral cortex - with impact on the diagnosis of diseases such as early dementia, epilepsy and small-vessel stroke, as well as understanding of vascularisation, myelin pathology and other phenomena. Furthermore, microbleeds can be identified, oxygen saturation quantified and vasculature mapped via techniques such as Susceptibility Weighted Imaging.

MolecularA key advantage of moving to ultra-high field is the improvements seen in (functional) spectroscopy - brought about by the higher sensitivity and specificity (spectral dispersion). As a result, it is possible to reliably identify many metabolites that are invisible with standard MRI. This opens up many opportunities for oncology, psychopharmacology and other disciplines.