A new study shows that a low-carbohydrate diet was equally good as the
weight loss drug orlistat (the active ingredient in Alli and Xenical) at
helping overweight and obese people lose weight, but people who followed the
low-carb diet also experienced a healthy drop in their blood pressure
levels.

"I expected the weight loss to be considerable with both therapies but we
were surprised to see blood pressure improve so much more with the
low-carbohydrate diet than with orlistat," researcher William S. Yancy, Jr.,
MD, an associate professor of medicine at Duke University Medical Center, says
in a news release. "If people have high blood pressure and a weight problem, a
low-carbohydrate diet might be a better option than a weight loss
medication."

Researchers say studies have already shown that the two weight loss methods
are effective at promoting weight loss, but it's the first time the health
effects of each have been compared head to head.

"It's important to know you can try a diet instead of medication and get the
same weight loss results with fewer costs and potentially fewer side effects,"
Yancy says.

Low-Carb Lowers Blood Pressure

In the study, published in the Archives of Internal Medicine, 146
obese or overweight adults were randomly divided into two groups. Many of the
participants also had chronic health problems, such as high blood pressure or
diabetes.

The first group was advised to follow a low-carbohydrate, ketogenic diet
consisting of less than 20 grams of carbohydrates per day, and the second group
received the weight loss drug orlistat three times a day, plus counseling in
following a low-fat diet (less than 30% of daily calories from fat) at group
meetings over 48 weeks.

The results showed weight loss was similar in the two groups. The low-carb
diet group lost an average of 9.5% of their body weight and the orlistat group
lost an average of 8.5%. Both weight loss methods were also not significantly
different at improving cholesterol and glucose levels.