Fusion

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

EIF5Bd

Eukaryotic initiation factor (170 aa)

Predicted Functional Partners:

EIF2Ab

Eukaryotic initiation factor (353 aa)

0.998

EIF2G

Eukaryotic initiation factor (462 aa)

0.998

EIF2Ba

Eukaryotic initiation factor (285 aa)

0.996

EIF2B

Eukaryotic initiation factor (434 aa)

0.995

EIF2Bc

Eukaryotic initiation factor (406 aa)

0.994

EIF2Bb

Eukaryotic initiation factor (314 aa)

0.993

EIF3G

Eukaryotic translation initiation factor (280 aa)

0.992

EIF3C

Eukaryotic initiation factor (912 aa)

0.991

EIF3A

Eukaryotic initiation factor; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome (844 aa)

0.991

EIF3B

Eukaryotic initiation factor; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome (718 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

EIF2Ab

EIF2B

EDP05564

EDO96862

Eukaryotic initiation factor

Eukaryotic initiation factor

0.996

EIF2Ab

EIF2Ba

EDP05564

EDO99198

Eukaryotic initiation factor

Eukaryotic initiation factor

0.994

EIF2Ab

EIF2Bb

EDP05564

EDO99765

Eukaryotic initiation factor

Eukaryotic initiation factor

0.994

EIF2Ab

EIF2Bc

EDP05564

EDO98644

Eukaryotic initiation factor

Eukaryotic initiation factor

0.993

EIF2Ab

EIF2G

EDP05564

EDP07730

Eukaryotic initiation factor

Eukaryotic initiation factor

0.998

EIF2Ab

EIF3A

EDP05564

EDP08669

Eukaryotic initiation factor

Eukaryotic initiation factor; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome

0.996

EIF2Ab

EIF3B

EDP05564

EDP04360

Eukaryotic initiation factor

Eukaryotic initiation factor; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome

0.991

EIF2Ab

EIF3C

EDP05564

EDO96632

Eukaryotic initiation factor

Eukaryotic initiation factor

0.995

EIF2Ab

EIF3G

EDP05564

EDP08487

Eukaryotic initiation factor

Eukaryotic translation initiation factor

0.977

EIF2Ab

EIF5Bd

EDP05564

EDP03599

Eukaryotic initiation factor

Eukaryotic initiation factor

0.998

EIF2B

EIF2Ab

EDO96862

EDP05564

Eukaryotic initiation factor

Eukaryotic initiation factor

0.996

EIF2B

EIF2Ba

EDO96862

EDO99198

Eukaryotic initiation factor

Eukaryotic initiation factor

0.997

EIF2B

EIF2Bb

EDO96862

EDO99765

Eukaryotic initiation factor

Eukaryotic initiation factor

0.997

EIF2B

EIF2Bc

EDO96862

EDO98644

Eukaryotic initiation factor

Eukaryotic initiation factor

0.997

EIF2B

EIF2G

EDO96862

EDP07730

Eukaryotic initiation factor

Eukaryotic initiation factor

0.986

EIF2B

EIF5Bd

EDO96862

EDP03599

Eukaryotic initiation factor

Eukaryotic initiation factor

0.995

EIF2Ba

EIF2Ab

EDO99198

EDP05564

Eukaryotic initiation factor

Eukaryotic initiation factor

0.994

EIF2Ba

EIF2B

EDO99198

EDO96862

Eukaryotic initiation factor

Eukaryotic initiation factor

0.997

EIF2Ba

EIF2Bb

EDO99198

EDO99765

Eukaryotic initiation factor

Eukaryotic initiation factor

0.998

EIF2Ba

EIF2Bc

EDO99198

EDO98644

Eukaryotic initiation factor

Eukaryotic initiation factor

0.998

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Network Stats

Network Stats analysis is still ongoing, please wait ...

Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: