Genotyping

High Resolution Melt (HRM) Analysis

This High Resolution Melt Analysis (HRM) app is designed for post-PCR analysis to identify variation in nucleic acid sequences. The method is based on detecting small differences in PCR melting (dissociation) curves. It is enabled by high-brightness, dsDNA-binding dyes used in conjunction with real-time PCR instrumentation that has precise temperature ramp control, advanced data capture capabilities, and access to software designed specifically for HRM analysis.

hPSC Scorecard Analysis

The hPSC Scorecard Analysis app scores gene expression profiles generated using the TaqMan hPSC Scorecard Panel compared to a reference set of well-characterized pluripotent stem cell lines. It provides raw data as well as box plots, heat maps, and correlation plots for export.

Presence/Absence Analysis

The Presence Absence Analysis app analyzes and interprets real-time PCR data or post-read data to determine if a specific target sequence is present (presence) or not present (absence) in a sample. It provides an easy-to-view presence/absence result in a plate grid view.

Relative Quantification

The Relative Quantification app allows fast and powerful gene expression analysis with enhanced visual capabilities for relative quantification including integrated correlation and volcano and cluster analysis with the ability to drill down to amplification plots.

Quality Check

The Quality Check app automatically checks CE sequence trace quality. It provides a results summary based on quality parameter settings and auto-flags lower quality traces for further inspection. Users can quickly and easily navigate to questionable or borderline data, and analyze, make adjustments, or exclude traces from the study.

Next-Generation Confirmation

The Next-Generation Confirmation app confirms NGS variants using CE technology. It allows users to easily visualize the variants detected by both NGS and CE platforms and to export confirmed variants in standard vcf format.

SeqStudio Plate Manager

The SeqStudio Plate Manager app enables the user to set up plates and configure different application-type runs for the Applied Biosystems SeqStudio Genetic Analyzer. It also supports remote monitoring and remote control of runs.

Peak Scanner

New Microsatellite Analysis

The Microsatellite Analysis app is microsatellite genotyping software that allows you to analyze a mixture of DNA fragments, separated by size. This analysis provides a profile of the separation, precisely calculates the sizes of the fragments, and determines the microsatellite alleles present in the sample. Microsatellite analysis is commonly used to study Microsatellite Instability in cancer and Triplet Repeat Expansion in neurodegenerative diseases, and for Species Identification & Characterization and Human Sample Authentication.

PCR Designer

CRISPR Search and Design Tool

Use the CRISPR app to search our database of >600,000 predesigned CRISPR gRNAs or to analyze your sequence of interest for de novo gRNA designs for use in genome editing with CRISPR-Cas9 technology. The CRISPR module enables easy purchase of CRISPR-Cas9 and associated Thermo Fisher Scientific products.

GeneArt QA

Use this module to browse, download and share Quality Assurance Documentation (QAD) for all your orders from GeneArt. Note that only QAD for orders shipped after you confirmed the Terms Of Use for the service will be uploaded and made available for review.

GeneArt™ Strings™ Assistant

Invitrogen™ CRISPR Array Designer

Use The Invitrogen™ CRISPR Array Designer Tool to design large number of CRISPRs for cell engineering experiment(s). The software will also assist customers in arranging oligonucleotides (containing CRISPR guide-RNAs) on 96-well plates. This is not associated with any instrument but has the underlying algorithm used by the GeneArt CRISPR Search and Design Tool. All of these products can be ordered by customers from Thermo Fisher Scientific.

Oligo Perfect

Use the OligoPerfect™ designer to design oligonucleotide primers for your PCR-dependent experiments. In addition to designing primers, the OligoPerfect™ designer enables easy purchase of oligonucleotides by Thermo Fisher Scientific.

Sequence Viewer

The Sequence Viewer module will allow users to load DNA sequence files and view relevant molecule information visually. Molecule features can be viewed as annotated sequences in intuitive graphical and sequence maps.

TAL

Use the TAL module to search our database of >600,000 predesigned TALs or to analyze your sequence of interest for de novo TAL designs for use in genome editing with TAL technology. The TAL module enables easy purchase of TALs and associated products by Thermo Fisher Scientific.

Pathway Over-Representation Analysis

The Pathway Over-Representation Analysis app uses statistical analysis to detect biological pathways that are either over- or under-represented in a list of input proteins. The software accepts a list of protein identifiers as input and reports significant WikiPathways and optionally KEGG (Kyoto Encyclopedia of Genes and Genomes) pathways associated with the list.

Sample Profiler

Sample Profiler identifies unknown compounds in high resolution accurate mass spectrometry sample data derived from defined populations. Once identified, these unknown compounds are compared against a database of representative compound profiles, complete with their chromatographic peak ranges. Data differences are analyzed via integrated hypothesis testing tools. Using this process, Sample Profiler elucidates how a new “challenge” sample differs from an existing representative profile; the app also measures how a sample population profile changes with time, location, production method, and more.

MS Instrument Connect

MS Instrument Connect provides the ability to monitor your LC-MS and GC-MS analyses remotely from any web-enabled device. Use this application to monitor real-time mass spectrometer status, track system utilization and historical events, and create email notifications to keep you informed when analytical runs are complete or when system errors occur. MS Instrument Connect is integrated with the Instrument Connect App, allowing you to track your systems from any iOS or Android device.

Omics Comparator

The Omics Comparator analysis software generates Venn diagrams to compare up to 5 lists of input proteins. The analysis can also work on lists of genes. The software displays set membership together with molecular annotations including color coded Gene Ontology terms.

My Pipette™ Connect Utility

The My Pipette Connect Utility for Windows enables E1-ClipTip electronic pipettes to link with the My Pipette Creator app. Please download and install to get started. The My Pipette Creator app helps to increase productivity by leveraging the power of the Thermo Fisher Cloud and the connectivity feature of the E1-ClipTip electronic pipette. This app allows users to efficiently create pipetting programs, collaborate by sharing programs with colleagues, and update pipette firmware. Programs can be easily transferred to and from the E1-ClipTip wirelessly or via a USB connection. Additionally, pre-written and validated protocols designed specifically for Thermo Fisher assays and kits are available which can dramatically reduce experiment setup time and minimize potential errors. For more information, please visit thermofisher.com/mypipette

My Pipette™ Creator

The My Pipette Creator app helps to increase productivity by leveraging the power of the Thermo Fisher Cloud and the connectivity feature of the E1-ClipTip electronic pipette. This app allows users to efficiently create pipetting programs, collaborate by sharing programs with colleagues, and update pipette firmware. Programs can be easily transferred to and from the E1-ClipTip wirelessly or via a USB connection. Additionally, pre-written and validated protocols designed specifically for Thermo Fisher assays and kits are available which can dramatically reduce experiment setup time and minimize potential errors. For more information, please visit thermofisher.com/mypipette

CosmosID

CosmosID's platform identifies bacteria and viruses in a whole genome shotgun metagenomic sample and is able to discriminate pathogens from their ‘near neighbors’ using statistical and computational methods, with no prior assumptions as to what is present in the sample.

Molecular spectroscopy

NanoDrop

The NanoDrop app gives you the flexibility to view and work with dsDNA, ssDNA and RNA data acquired with the NanoDrop One and the NanoDrop 2000 instruments on any device. You can access all of the Acclaro Sample Intelligence Technology information associated with your NanoDrop One data. Contaminant information can be displayed and reviewed with an interactive spectral display.

OMNIC™ Anywhere

The OMNIC™ Anywhere app allows you to extract the content of an SPA file and visualize its data within an interactive spectral display. You can perform basic operations on it, such as find the peaks of the spectrum trace and download its graph view as an image ready to be included in your reports.

iBright Image Analysis Software

iBright Image Analysis (iBA) software is an easy to use application for automated data analysis and management of digital images depicting electrophoresis gels and blots. The software can be used for editing images (e.g., to adjust brightness/contrast, rotation, crop, false coloring, etc) as well as identification and quantitation of bands, background subtraction, relative and absolute quantitation, molecular weight analysis, and report generation. This application supports the iBright CL 1000 and iBright FL 1000 Imaging systems.

ProQuantum

The ProQuantum™ software enables you to analyze ProQuantum™ protein immunoassay results acquired from any qPCR instrument. The analysis features include standard curve qualification with built-in outlier detection, interpolation of unknown samples for quantitation, and group-wise statistical analysis. Step-by-step guidance is provided for preparation of an assay run, including setting up the standard curve, plate layout design, and customized bench instructions.

Education Connect

Education Connect is an online classroom companion supporting LabCoat Live™— the first of its kind, virtual hands-on learning program. The capability provides all of the resources needed for your individualized scientific learning plan. Features include live lecture space for theoretical and data analysis overviews, resource libraries for course lecture notes, protocols, instructional videos, and a discussion board enabling peer-to-peer and participant-to-instructor communication for up to two months after course completion.

Oncomine Knowledgebase Reporter

Oncomine Knowledgebase Reporter helps you prioritize variants, find the relevant cancer drivers, and create a report that enables contextual investigation of sample-specific variants to understand their use with respect to current labels, guidelines, and global clinical trials. It is a genomic analysis tool developed specifically for further examination of NGS data, enabling streamlined access to a final report in just a few easy steps.