Here's a couple of pretty ruthless bugs I ran into during my recent playthroughs.

Alpha version: 10.0Bug description, with steps to reproduce: Knives can't be thrown. They just won't move. They float there for a few moments and then fall to the ground comically, like in a Looney Tunes cartoon.Have you loaded a game before encountering this bug? Yes.

Alpha version: 10.0Bug description, with steps to reproduce: After fighting Wolfman in the Sawmill, I ended up locked in there because he doesn't drop the key anymore. Also, there's an additional assault rifle on his corpse, on top of the one he empties into you and drops before rushing you down in melee.Have you loaded a game before encountering this bug? Yes, still no key to be found.