Faye Valentine. The character first appears in the Cowboy Bebop anime series episode "Honky Tonk Women" (1998).

Jill Valentine. The character first appears in the video game Resident Evil (1996).

Mai Valentine. The character first appears, as far as I can determine, under her Japanese name of Mai Kujaku, in the Yu-Gi-Oh! manga Chapter 65: "Fate on the Ocean!" (1998). Her English adaptation name is first used in the Yu-Gi-Oh! animated series episode "Journey to the Duelist Kingdom" (dub title; 2001).

Melody Valentine. The character first appears in the comic book She's Josie #1 (1963). Her surname of Valentine is established in the live-action feature film Josie and the Pussycats (2001).

Vexy Smurf. The character first appears in the film The Smurfs 2 (2013).

Victini. The character first appears in the video games Pokémon Black and White Versions (2010).

Victoria (Granbull). The character first appears, as an unnamed Snubbull, in the Pokémon anime episode "[Snubbull]'s Magnificent Life!?" (1999). It evolves into Granbull in "[Meowth], [Snubbull], and Granbull!?" (2000).

James's Victreebel. The character first appears as an unnamed Victreebel in the Pokémon anime series episode "The Secret of the Breeding Center" (1998).

Vigo. The character first appears in the Star Trek: The Next Generation novel The Valiant (2000).

Vilgax. The character first appears in the Ben 10 animated series premiere episode "And Then There Were Ten" (2005).

Don Jaime Villegas. The character first appears in the novel The Bridge of San Luis Rey (1927).

Edward "Edd" Vincent. The character first appears in the Ed, Edd n Eddy animated series premiere episode "The Ed-Touchables" (1999). His surname is arbitrary.

Jackson Vincent. The character first appears, as Junichi, in the Pokémon broadcast animated film Raikou - Legend of Thunder (2001), His English given name is established as Jackson in the regular episode English adaptation "Tie One On!" (2003). He is named Vincent in the English adaptation of the original film (2005).

Viridi. The character first appears in the video game Kid Icarus: Uprising (2012).

Virion. The character first appears in the video game Fire Emblem: Awakening (2012).

Amelia Voght. The character first appears in the comic book The Uncanny X-Men #300 (1993).

Dennis Volkner. The character first appears, with the Japanese name of Denzi, in the video games Pokémon Diamond and Pearl Versions (2006). His English name, Volkner, is established in the North American release (2007). His given name is arbitrary.

Linka Volkova. The character first appears in the Captain Planet and the Planeteers animated series premiere episode "A Hero for Earth" (1990). Her surname is arbitrary.

Franziska von Karma. The character first appears, with her original Japanese name of Karuma Mei, in the video game Turnabout Trial 2 (2002). Her English dub name Franziska von Karma is established in the English adaptation Phoenix Wright: Ace Attorney: Justice for All (2007).

Manfred von Karma. The character first appears, with his original Japanese name of Karuma Go, in the video game Turnabout Trial (2001). His English dub name Manfred von Karma is established in the English adaptation Phoenix Wright: Ace Attorney (2005).

James von Rich.]]] The character first appears, as Kojiro, in the Pokémon anime episode "Showdown! Pokémon Center!" (1997). His dub name of James is established in the English adaptation of the episode, "Pokémon Emergency" (1998). His surname is arbitrary.

Andrea von Strucker/Fenris. The character first appears in the comic book Uncanny X-Men #194 (1985). Her surname and code-name are revealed in Uncanny X-Men #200 (1985).

Andreas von Strucker/Swordsman/Fenris. The character first appears in the comic book Uncanny X-Men #194 (1985). His surname and Fenris code-name are revealed in Uncanny X-Men #200 (1985). He first appears as the Swordsman in New Thunderbolts #2 (2005).