A newly discovered gene is able to block HIV infection and therefore may in turn prevent the onset of AIDS. Researchers at the University of Alberta in Edmonton and the University of Pennsylvania School of Medicine in Philadelphia identified a human gene called TRIM22 that can halt HIV infection in cell culture by preventing assembly of the virus (Barr SD et al. PLoS Pathog. 2008;4[2]:e1000007. 10.1371/journal.ppat.1000007).