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Kay Underwood, 20, has cataplexy, which means that almost any sort of strong emotion triggers a dramatic weakening of her muscles. Exhilaration, anger, fear, surprise, awe and even embarrassment can also cause sufferers to suddenly collapse on the spot.

Kay, of Barrow-upon-Soar, Leicestershire (UK), who was diagnosed with the condition five years ago, once collapsed more than 40 times in a single day. She said: “People find it very odd when it happens, and it isn’t always easy to cope with strangers’ reactions.

Like most cataplexy sufferers, Ms Underwood is also battling narcolepsy – a condition that makes her drop off to sleep without warning. Narcolepsy affects around 30,000 people in the UK and about 70 per cent of them also have cataplexy.

17-month-old Ella-Grace Honeyman was born with a rare malformation of the blood vessels in the brain called Vein of Galen Malformation. The malformation causes high pressures in the vein of Galen, resulting in aneurysms. In Ella-Grace, news reports state that the high pressure caused blood to leak into her brain and resulted in the formation of a potentially fatal aneurysm.

The condition is so rare, that the toddler had to be taken first to France, and then to the United States for treatment. She underwent surgery that plugged the tiny holes in her blood vessels with a type of medical superglue. While she will still need more operations in the future, doctors say Ella-Grace will now be able to live a long and healthy life.

A woman with an inoperable brain tumor is spending £40,000 on plastic surgery – so she can die looking like movie star Demi Moore. Lisa Connell, 29, will use the money her mom Angela had saved up for Lisa's wedding to pay for her new look.

Despite being a stunning brunette, Lisa has never been happy with her appearance and is convinced the surgery will make her look as beautiful as Demi, who is no stranger to cosmetic surgery herself. In a race against time, Lisa will undergo liposuction, a breast enhancement and eyebrow lift, plus extra work on her skin and teeth to fulfill her dream.

Lisa was just 27 when she was diagnosed with an inoperable brain tumor known as meningioma.

Known as the "Octomom" by the media, Nadya Denise Doud-Suleman Gutierrez came to international attention after she gave birth to octuplets in January 2009. Her set of octuplets are only the second to be born alive in the US and they quickly surpassed the previous worldwide survival rate for a complete set of octuplets set by the Chukwu octuplets in 1998. Suleman, an unemployed single mother, already had other six young children at home at the time, and along with the octuplets, they were all conceived via in-vitro fertilization, which has led to a lot of controversy.