Wolf has been pitching in the same misfortune as Greg Maddux. Sunday's game marked the seventh time this season Wolf has taken the loss or received no decision in a game in which he allowed two or fewer runs over six innings. And Wolf has allowed two or fewer runs over at least six innings in seven of his 12 starts.

Wolf is 9-5 lifetime against the Mets with a 3.44 ERA over 25 starts. He is 2-1 with a 3.00 ERA in five starts at Petco Park this season. Left-handed hitters are batting .326 (14-for-43) against Wolf compared to .240 (53-for-221) by right-handed hitters.

Santana is 1-1 with a 3.55 ERA in two career starts against the Padres. This will be his first start at Petco Park.