Tympanic membrane perforations can be caused by many different factors including infection, penetrating trauma by foreign bodies or surgical instruments inserted into the external auditory canal or blunt or blast trauma.

The remaining material is organized by anatomy, with seven chapters focusing on the external auditory canal and pinna; the middle ear and mastoid; temporal bone vascular anatomy, anomalies, and disease, with an emphasis on pulsatile tinnitus; the inner ear and otodystrophics; temporal bone trauma; anatomy and development of the facial nerve; and the vestibulocochlear nerve, with an emphasis on the normal and diseased internal auditory canal and cerebellopontine angle.

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