Test Includes

Use

Determine the susceptibility of nontuberculous slowly-growing mycobacterial isolates to a profile of antimycobacterial agents. Interpretive categories for MICs are not yet available due to lack of clinical trial data that would indicate the clinical efficacy.1,2 For the unusual mycobacteria, susceptibility data is often useful as an aid in identification.

Limitations

Susceptibilities cannot be reported if the organism fails to grow in the test medium. Susceptibilities cannot be performed on mixed cultures. An organism identification is required prior to reporting susceptibility results.

Results of this test are labeled for research purposes only by the assay's manufacturer. The performance characteristics of this assay have not been established by the manufacturer. The result should not be used for treatment or for diagnostic purposes without confirmation of the diagnosis by another medically established diagnostic product or procedure. The performance characteristics were determined by LabCorp.

Methodology

Sensititre® broth microdilution (MIC)

Additional Information

Failure to take all drugs in a multidrug regimen can lead to a shift toward resistant organisms and treatment failure.3 Susceptibility testing to rifampin is the only drug currently recommended for primary susceptibility testing of M kansasii.2 Isolates susceptible to rifampin are susceptible to rifabutin.

Test results are not intended to be used as the sole means for patient management.