To the Editor: Popular wisdom holds that not
getting enough sleep increases the propensity of catching a cold or other
ailments. In America, sleep duration has steadily declined from nearly 9 hours
in 1960 to less than 7 hours currently.1,2 Although
adverse effects of sleep deprivation on immune parameters have been documented,3 the clinical implications of these findings are
unclear. We examined the effect of sleep deprivation on immune response to
influenza vaccination.