This is structure in water. This is an antimicrobial peptide released by pepsin cleavage of lactoferrin, an 80 kDa iron-binding glycoprotein with many immunologically important functions. The NMR structure of LfcinB reveals a somewhat distorted antiparallel beta-sheet. This contrasts with the X-ray structure of bovine lactoferrin, in which residues 1-13 (of LfcinB) form an alpha-helix (Hwang et al. 1998). Human lactoferricin (1z6v, 1z6w) also forms an alpha-helix. A six-residue segment of bovine lactoferricin was studied in SDS micelles (1y58, 1y5c).