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The Mission of Hydroxypropyl Beta Cyclodextrin

- Nov 26, 2018 -

The high solubility of hydroxypropyl beta cyclodextrin and its unique cavity structure are the main aspects of its role. Hydroxypropyl beta cyclodextrin can effectively encapsulate some pharmaceutical ingredients, odors, metal ions, and release the substrate under certain conditions, so that the substrate can play its due role. Hydroxypropyl beta-cyclodextrin (HPBCD) plays an important role in transportation. It can also be regarded as a supramolecular capsule, and it is non-toxic, non-irritating and non-polluting, which makes it more and more widely used. For example, when the hydroxypropyl beta cyclodextrin complex is injected into the human body, the substrate molecule is released quickly, almost without affecting the original pharmacology of the drug.

The inclusion of guest molecule has many advantages. After inclusion of guest molecule, solubility increases, stability improves, liquid products can be powdered, which can prevent volatilization of volatile components, mask the bad odor or taste of drugs, regulate the release rate, improve the bioavailability of products, and reduce the irritation and toxicity of drugs. Function and so on. For example, adding hydroxypropyl beta cyclodextrin in cosmetic preparation can improve the stability of raw materials in the cosmetic formulation system and make the emulsion prepared by it more stable.

Hydroxypropyl beta cyclodextrin as a new type of functional molecules, the research and application will be more and more widely.