Why are you using such a high amount of T? That’s over 2,000ng/dl people normally aim to be around 800 on TRT. You will run into issues in the long term at that dosage, I would be running around half that dosage. Also consider increasing injection frequency to at least E3D that will help keep levels more stable and e2. The key to effective long term TRT is to not need an AI by finding the right dosage and frequency (unless you’re someone that is super prone)

I agree with others… lower your dose of T. Your HDL is already low and arimadex tends to lower HDL and increase LDL. You could solve the problem by simply lowering test. I prefer to find a spot where no AI is needed. It took me two years to figure it out but I did and I feel better than ever with no AI. My cholesterol improved dramatically too.

Hormones are derived from cholesterol, so without it you have no hormones. Nobody knows the normal range for estrogen as it’s not well studied, the current ranges are a best guess based on limited information.

You are ignoring free estrogen, like free testosterone it’s bioavailable. We assume high free testosterone likely means high free estrogen, the difference is going to be how well you liver removes estrogen from the body.

This may be why some men can get away with higher estrogen and not have any symptoms, if you don’t excrete estrogen well, you may need estrogen on the lower end

That’s 2072ng/dL! I take 200mg/week, it’s not a massive dose. When were those labs pulled, relative to your last injection? I get less than half those numbers at trough.

When my doc first put me on TRT I was given 150mg/wk T cyp split M/W/F on week 8 I had what I would call extreme libido issues and did a mini blood test. it came back >1500ng/dL. It was the cheap test I know now to ask for the full range TT.

Hard to pick a trough when you inject 3 times a week. So I picked Monday 8am before shot.
My ShGB was 24 at the time. I can see 200 giving one a +2000 even in trough.

You might not have to cut it in half. But if you continue with the 200 sooner or later your blood would thicken and you would have to start donating blood to keep it thin but you can only do that a short while before your ferritin would crash. We all would love to be able to run 200-300mg/wk but our bodies just won’t allow it. 2000ng/dL is not healthy it just allows you to build big muscles and pound nails with your stiffy. haha

That’s interesting. I have to think that is unusual though. Mine is 900/220. SHBG also 24. I know a few guys also taking 200mg. I’ll have to ask them. Wonder what my test would have been when I was competing and taking 800?

That’s interesting. I have to think that is unusual though. Mine is 900/220. SHBG also 24. I know a few guys also taking 200mg. I’ll have to ask them. Wonder what my test would have been when I was competing and taking 800?

It might depend on frequency of injections. Once a week is going to have a deeper trough than EOD. To keep my Free T in range and my HCT in check without donating I can’t run more than 120/wk. That does not stop me from blasting every now and then, Haha.

Do you feel bad when your Hct gets high? At what point do you start to notice symptoms?

Sorry highpull, This forum never tells me when someone copies a comment I posted. I just saw this thread.
When my HCT hit ~52 my blood pressure goes up 10 points on the top and bottom. I don’t really notice much but as soon as my BP goes up I either donate blood or drop my T cyp dose to below 100/wk. Either fixes the HCT and BP issues.
Now a days I just find it easier to cruise at 70-90mg/wk (no AI or donations needed) and blast at ~400 twice a year. That seems to let me build and keep muscle. While blasting I do use anastrozole to keep the E2 and prolactin low as well as doxazosin and cialas to keep the BP in check.