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Witnesses said a wrong-way driver crashed into the truck before the explosion.

The wrong-way driver was identified as a 30-year-old man. He was killed in the incident.

"As you can see, we have quite a bit of a large scene, large explosion is going on right now, fire had to let that burn out before they ran to put foam on that. We do have a hazmat response as a result of that," Lt. Mark Ponichtera said. "We have multiple thoroughfares that are shut down here, all lanes on 75 are shut down at this moment."