Captain Mal Reynolds and his motley crew of space traders get a job that seems to be right up their alley. Gangster Adelai Niska wants them to rob a train and deliver the goods to them. Mal and Zoey have little trouble getting the job done and even convincing the local authorities that are just a married couple who have come looking for work. When the overhear that the stolen cargo was urgently needed medical supplies, Mal reconsiders whether he wants to do Nishka's dirty work. Back on the ship, Dr. Simon Tam continues to worry about his sister River who is still having nightmares about her institutionalization.