The purpose of this prospective study was to determine quality of life of patients after stroke in Osijek-Baranya County. The research included 161 patients 82 men and 79 women who had their first acute stroke and were treated at Department of Neurology, Osijek University Hospital Center. The Barthel Index BI was used to assess functional deficiency and SS-QOL Stroke-Specific Quality of Life questionnaire was used for self-evaluation of patients’ physical and mental health. The first assessment was carried out in the acute phase of the disease, and control assessments 30, 90 and 180 days after the stroke. Mean Barthel Index score was higher at every successive measurement 55, 80, 95, 95. All BI items were statistically significant Friedman, p