https://journals.aiac.org.au/index.php/ABCMED/issue/feedAdvances in Bioscience and Clinical Medicine2018-08-27T01:43:40+10:00ABCMed Editorial Officeeditor.abcmed@aiac.org.auOpen Journal Systems<p><strong>Advances in Bioscience and Clinical Medicine (ABCmed)</strong> is an international open-access, peer-reviewed journal established in Australia. ABCmed spans all areas of bioscience and medicine publishing original research articles, review articles, short communications, case reports and correspondences. Both printed and online versions of ABCmed are available. The journal is indexed in leading indexing and abstracting services, including but not limited to NLM catalog, proquest, DOAJ, etc. Authors are encouraged to submit their manuscripts for review as there is no article submission and article processing charges. </p><table border="0" cellspacing="0" cellpadding="0"><tbody><tr><td valign="top" width="417"><p><strong>ABCmed <strong>Highlights</strong></strong></p><ul><li><strong>Country of Publication: </strong>Australia <strong> </strong></li><li><strong>Publisher:</strong> <a href="http://www.aiac.org.au/" target="_blank">Australian International Academic Centre PTY.LTD.</a></li><li><strong><strong>Online </strong>ISSN:</strong> <a href="http://trove.nla.gov.au/work/186657819?selectedversion=NBD52153834" target="_blank">2203-1413</a></li><li><strong>Print ISBN:</strong> 9781291449501</li><li><strong><strong>Imprint</strong>:</strong> <a href="http://www.lulu.com/spotlight/AIAC" target="_blank">LuLu Press Inc.</a></li><li><strong>Acceptance Rate</strong>: <a href="/index.php/ABCMED/about/history">18% in 2017</a></li><li><strong>Frequency:</strong> Quarterly [2015 Onwards]</li><li><strong>Publication Dates:</strong> January, April, July, October </li><li><strong>Language:</strong> English</li><li><strong>Format:</strong> Print &amp; Online</li><li><strong>Scope:</strong> Bioscience and Clinical Medicine </li><li><strong>Article Processing Charges: </strong><a href="http://www.journals.aiac.org.au/index.php/ABCMED/about/editorialPolicies#custom-2">No</a></li><li><strong>Open Access:</strong> Yes</li><li><strong>Refereed:</strong> Yes</li><li><strong>Abstracted:</strong> <a href="/index.php/ABCMED/about/editorialPolicies#custom-0">Yes</a></li><li><strong>Indexed:</strong> Yes</li><li><strong>Policy:</strong> <a href="/index.php/IJKSS/about/editorialPolicies#peerReviewProcess">Peer-reviewed</a></li><li><strong>Peer Review Time:</strong> Five to Six Weeks</li><li><strong>E-mail: </strong>editor.abcmed@aiac.org.au</li></ul></td><td valign="top" width="209"><p> <img src="/public/site/images/admin/vol_11.jpg" alt="" /></p></td></tr></tbody></table><div><br /><table border="0" cellspacing="0" cellpadding="0"><tbody><tr><td valign="top" width="432"><p> <strong>Most Downloaded Articles</strong></p></td><td valign="top" width="432"><p> <strong>Most Cited Articles <em><strong>via Google Scholar</strong></em></strong></p></td></tr><tr><td valign="top" width="432"><ol><li><a href="/index.php/ABCMED/article/view/642">APRV Mode in Ventilator Induced Lung Injury (VILI)</a> <em>Read 188 Times</em></li><li><a href="/index.php/ABCMED/article/view/2419">Sugammadex in patients with chronic renal failure: two case reports</a> <em>Read 141 Times</em></li><li><a href="/index.php/ABCMED/article/view/672">High Caloric Diet for ALS Patients: High Fat, High Carbohydrate or High Protein</a> <em>Read 132 Times</em></li><li><em><a href="/index.php/ABCMED/article/view/1755">Comparison between primary closure and T-tube drainage after open choledocotomy</a> <em>Read 112 Times</em></em></li><li><a href="/index.php/ABCMED/article/view/1545">Is ginger (Zingiber officinale) mouthwash a convenient therapeutic for denture stomatitis?</a> <em><em>Read 100 Times</em></em></li></ol></td><td valign="top" width="432"><ol><li><a href="/index.php/ABCMED/article/view/642">APRV Mode in Ventilator Induced Lung Injury (VILI)</a> <em>Cited 5 Times</em></li><li><a href="/index.php/ABCMED/article/view/1548">Efficacy of Microwave Disinfection on Moist and Dry Dental Stone Casts with Different Irradiation Times</a> <em>Cited 3 Times</em></li><li><a href="/index.php/ABCMED/article/view/678">Facial Soft Tissue Thickness in North-West of Iran</a> <em>Cited 3 Times</em></li><li><a href="/index.php/ABCMED/article/view/658">Frequency of Burnout, Sleepiness and Depression in Emergency Medicine Residents with Medical Errors in the Emergency Department</a> <em>Cited 3 Times</em><br /><br /></li></ol><span> Updated on 20 February 2018</span></td></tr></tbody></table></div>https://journals.aiac.org.au/index.php/ABCMED/article/view/4592Methotrexate in Unruptured Ectopic Pregnancy: Comparing the Single- and Double-dose Treatment2018-08-27T01:43:39+10:00Nazli Navalinavalin@tbz.ac.irNasim Jabbari Aslnavalin@tbz.ac.irSanaz Moosavinavalin@tbz.ac.irIntroduction: Ectopic pregnancy (EP) poses a great threat to pregnant women, and in case of misdiagnosis could lead to catastrophic death of the patients. EP patients tend to be treated with surgical or non-surgical treatments. One of the most common therapies in managing EP is Methotrexate (MTX), which the efficacy of its single- and double-dose treatments will be evaluated in this study. Methods: One-hundred and twenty patients with EP, diagnosed in AL-Zahra hospital in Tabriz, Iran, were involved in the study and were divided, randomly, into two groups of 60 (though 4 of the patients in the second group left the study due to discontent, afterwards). For the first group 50 milligrams (mg) of intramuscular (IM) single-dose MTX was prescribed, while for the second group two doses of 50 mg IM MTX were prescribed. The levels of β-hCG were evaluated before the treatment, in the fourth and seventh days, and second and fourth weeks after the treatment. In addition, sonographic findings, clinical symptoms before the treatment, and side effects after treatment were recorded. Results: Success rate for the single-dose group was 85%, while for the double-dose group was 94.6%. However, there was no statistically significant difference between two groups. In addition, there were no significant relations between 2 groups in endometrial thickness, presence of abdominal free fluid and gestational age with the success rate. Regardless, the initial level of β-hCG was an indicator of treatment success rate. In patients with double-dose MTX, required period of time for β-hCG levels to reduce down to zero was significantly lower than the other group. Cut-off point for success rate with single-dose MTX was 3350, with the sensitivity of 88.9% and specificity of 76.5% and for the other group it was 3894.5, with the sensitivity of 66.7% and specificity of 71.7%. Conclusion: No significant difference was observed between single- and double-dose MTX groups in treating EP. The initial levels of β-hCG and mass size were the only factors to predict the treatment success rate. Double-dose regimen lowered β-hCG down to zero earlier than single-dose. Based on Cut-off points, while the initial β-hCG level was below 3350, single-dose treatment was efficient, whereas, between 3350 and 3894.5, double-dose treatment2018-07-31T00:00:00+10:00Copyright (c) 2018 Nazli Navali, Nasim Jabbari Asl, Sanaz Moosavihttps://journals.aiac.org.au/index.php/ABCMED/article/view/4593Compare the Effects of Epinephrine and Vasopressin in Return of Spontaneous Circulation2018-08-27T01:43:39+10:00Samad Shams Vahdatishams@tbzmed.ac.irAzra Nejabatianshams@tbzmed.ac.irFarzad Rahmanishams@tbzmed.ac.irParia Habibollahishams@tbzmed.ac.irPegah Sepehri Majdshams@tbzmed.ac.irBackground: There is a conflict in the superiority of each of the vasopressin and epinephrine compared to the other. Vasopressin has a vasoconstrictive action that results in an increase of the coronary perfusion pressure. Due to the expensive and sometimes scarce of vasopressin in most hospitals, this study aims to evaluate the response rate of vasopressin compared with epinephrine, in return of ROSC. Methods: In this descriptive-analytical study all patients in the emergency medicine department were enrolled in the study suffered a cardiopulmonary arrest and resuscitation will be done instantly for them (According to the guidelines AHA 2010). Their data were extracted from the hospital records and the success rate of recovery, 3-month survival and complications in patients recovering from the drug used during the CPR were analyzed. Results: A total of 61 patients record were analyzed. 31 patients had received epinephrine alone and 30 patients received a combination of epinephrine and vasopressin. No significant difference was observed between the two groups in terms of sex, sepsis, hypovolemia, renal failure, cancers, drug toxicity, brady, dysrhythmia, PEA, VT, VF, defibrillator, duration of CPR and three month outcome. The mean time of CPR in combination of epinephrine and vasopressin group was 27.26±12.72 and the mean time of CPR in epinephrine group was 27.24±13.510 (p-value= 0.99).Conclusion: Among patients with in-hospital cardiopulmonary arrest in this study no statistically significant difference was obtained between the results of treatment with epinephrine alone and combination of epinephrine and vasopressin.2018-07-31T00:00:00+10:00Copyright (c) 2018 Samad Shams Vahdati, Azra Nejabatian, Farzad Rahmani, Paria Habibollahi, Pegah Sepehri Majdhttps://journals.aiac.org.au/index.php/ABCMED/article/view/4594The Relationship between Eccentric Occlusion with Temporomandibular Disorders (TMD) and Para-functional Habits among Dentistry Students of Tabriz University of Medical Sciences in 20172018-08-27T01:43:39+10:00Alireza PournasrollahFatemeh.dabaghitabriz@gmail.comHosein EslamiFatemeh.dabaghitabriz@gmail.comVahid FakhrzadehFatemeh.dabaghitabriz@gmail.comFatemeh Dabaghi-TabrizFatemeh.dabaghitabriz@gmail.comMahdi RahbarFatemeh.dabaghitabriz@gmail.comSahar Khadem-neghadFatemeh.dabaghitabriz@gmail.comMasud RahmaniFatemeh.dabaghitabriz@gmail.comAim: The aim of this study is to investigate the relationship between side occlusion with temporomandibular joint problems (TMD) and parafunctional habits among Dentistry Students of Tabriz University of Medical Sciences. Materials and Methods: In this cross - sectional study, 98 students from the School of Dentistry of Tabriz University of Medical Sciences were randomly selected, and the occlusion was also examined. Data from the study were analyzed using descriptive statistics and chi-square test software SPSS 17. Results: In this study, 16.33 % of population had Group function occlusion, 13.23 % had Anterior Group function occlusion and 70.4 % had canine raise occlusion. 3.1% of people had functional Paralympic symptoms of Bruxism and 6.1 % were marked with Parafunctional clenching. The study population consisted, all patients with Group function occlusion that had para-functional habits. However, in patients with canine raised occlusion, 63.3 % para-functional habit parameters, 2 % has Bruxism and 1.5 % had clenching. Conclusions: a significant relationship was not observed between side occlusion with parafunctional habits and TMD problems among students of Tabriz University of Medical Sciences.2018-07-31T00:00:00+10:00Copyright (c) 2018 Alireza Pournasrollah, Hosein Eslami, Vahid Fakhrzadeh, Fatemeh Dabaghi-Tabriz, Mahdi Rahbar, Sahar Khadem-neghad, Masud Rahmanihttps://journals.aiac.org.au/index.php/ABCMED/article/view/4595Hearing in Children with Phenylketonuria2018-08-27T01:43:40+10:00Siamak Shivayj_moghaddam@yahoo.comYalda Jabbari Moghaddamyj_moghaddam@yahoo.comBackground: Phenylalanine is an essential Acid Amine participates in protein synthesis by tyrosine. High levels of phenylalanine in the body lead to the production of large quantities of phenyl ketone, which is excreted through urine and that is why it called as Phenylketonuria. A defect of IQ and attention, visual ability and speech processing in this patient. the aim of this study was hearing threshold evaluation of this patient. Method: In a cross-sectional, descriptive study auditory brain stem responses and otoacoustic emission of patients from 1 to13 years and control group age range of 1 to 14 years evaluated. Results: In 31 patients (62%) delay in ABR waves were outside of the normal range but the overall mean of all waves had in the normal range and the average interval of waves in patients with delay in treatment delay was more than patients group with early treatment. Conclusion: delayed-treatment was faced with more delays in the intervals between ABR waves, although statistically was not significant.2018-07-31T00:00:00+10:00Copyright (c) 2018 Siamak Shiva, Yalda Jabbari Moghaddamhttps://journals.aiac.org.au/index.php/ABCMED/article/view/4596A Silent Congenital Ethmoidal Encephalocele Progressing into Frontoethmoidal Meningoencephalocele with Episodic Seizures in Adulthood: A Case Report and Literature Review2018-08-27T01:43:40+10:00Xiang Yangneurovip@yeah.netXiaolin Aineurovip@yeah.netSeidu A. Richardneurovip@yeah.netJianguo Xuneurovip@yeah.netBackground: Frontoethmoidal meningoencephalocele (FEM) is rare congenital malformations that has specific geographic distribution. This condition is depicted with herniation of brain tissue as well as meninges via a defect in the cranium at the frontal, orbital, nasal as well as ethmoidal regions. Although several cases have been reported, none of them have a silent and progressive nature with episodic seizures. Case Presentation: We present a 20-year-old man with a swelling on the nasal bridge which was notice a few years after birth. The swelling initially progressed slowly without any symptoms from childhood through adolescents. Both CT scan and MRI revealed a defect in cranium at the frontal and ethmoidal regions with herniation of meninges and brain matter into the nasal cavity but no fistula. We successfully reduced the encephalocele as well as watertight closed the dura mater. The skull defect repaired, and left orbital defect also reconstructed via surgery. Conclusions: Aflatoxins, generated by one genus of a defective fungi, aspergillus could be responsible for the development of this malformation. We suggest that pregnant women in areas with high incidence of the malformation be screen thorough with ultrasound scan to detect the malformation earlier. We also suggest that further studies on the malformation be geared toward using 3D ultrasound to study the pathophysiology of this malformation.2018-07-31T00:00:00+10:00Copyright (c) 2018 Xiang Yang, Xiaolin Ai, Seidu A. Richard, Jianguo Xuhttps://journals.aiac.org.au/index.php/ABCMED/article/view/4597Intraoral Surgical Management of the Multiple Giant Submandibular Sialolithiasis2018-08-27T01:43:40+10:00Javad YazdaniPhoenixinfire@ymail.comAtena Afzali MehrPhoenixinfire@ymail.comMohsen HashemiPhoenixinfire@ymail.comTanaz AbdolahiPhoenixinfire@ymail.comFarzin AhmadpourPhoenixinfire@ymail.comSialolithiasis is considered one of the most common diseases of the salivary gland, mainly affects submandibular glands. In the current case, a 57‑year‑old male complaining of a tender solid mass in the right sublingual area was cadidate to undergo surgical treatment. The patient suffered swelling and pain for 11 months. Imaging revealed multiple unilateral salivary stones in the submandibular glands. The sialoliths were removed through intraoral approach under local anesthesia. Examination revealed four sialoliths, one of them sized larger than 37 mm in length. Beside those giant sialolithes, what makes this case is unique is the patient’s endocrine disorder, the secondary hyperparathyroidism. So it would be plausible to consider checking possible endocrine and electrolyte imbalance in such cases alongside correct selection of surgical treatment plane.2018-07-31T00:00:00+10:00Copyright (c) 2018 Javad Yazdani, Atena Afzali Mehr, Mohsen Hashemi, Tanaz Abdolahi, Farzin Ahmadpourhttps://journals.aiac.org.au/index.php/ABCMED/article/view/4598The Most Accurate and Fastest Method for Measurement of Vena Contracta Area by Direct Planimetry 3D Transesophageal Echocardiography2018-08-27T01:43:40+10:00Mehrnoush Toufandnashouri@yahoo.comDina Ashouridnashouri@yahoo.com<p><strong>Dear Editor,</strong></p><p> Two-dimensional (2D) echocardiography is a powerful tool for assessment of mitral regurgitation (MR) [1]. However, it bears several major disadvantages. Evidence suggests that measurement of the vena contracta area (VCA) via a three-dimensional (3D) method is significantly more accurate than 2D methods in the quantification of MR since the 2D method is not sufficiently reliable in calculation of VC diameter because of circular assumption of VC area [2]. VCA direct planimetry (DP) and multiplanar reconstruction (MPR)-derived VCA are direct and reliable methods to quantify MR severity, and their results are comparable with those of 2D integrative method [2, 3]. It is strongly recommended that these methods especially DP can replace 2D methods in the quantification of MR in the clinical practice, as it is more accurate and easy to perform [3].</p>2018-07-31T00:00:00+10:00Copyright (c) 2018 Mehrnoush Toufan, Dina Ashouri