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We are pleased to present a special issue of Psychosomatic Medicine, focused on the theme of “Diabetes, Obesity, and the Brain.”

Dr. Susan Everson-Rose of the University of Minnesota and Dr. John Ryan of the University of Pittsburgh served as Guest Editors of the issue. As noted in their introductory article and accompanying podcast, the articles in this issue highlight some of the critical new findings and challenges related to preventing and treating the adverse consequences of diabetes and obesity on brain structure and function as well as neurocognitive functioning.

—Willem J. Kop, Editor-in-Chief, Psychosomatic Medicine

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Social and environmental factors in early life play a critical role in shaping morbidity and mortality. Exposure to a wide range of adverse childhood experiences—including poverty, abuse, neglect, and violence—is associated with elevated risk for the onset of both physical and mental health disorders across the life course. Despite strong evidence for the links between adverse childhood experiences and health outcomes, the mechanisms that underlie these associations remain poorly understood. This is particularly true in the domain of physical health. Exploring these mechanisms is the goal of an upcoming special issue of Psychosomatic Medicine.

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