This online course includes all the recorded presentations, course materials, and case studies from the live 2018 Molecular Pathology Outreach Course held on October 31, 2018 in San Antonio, TX.

CME/CMLE and SAMs credit are available with the purchase of this course.

This course is designed to provide an overview of techniques and instrumentation used from the framework of the "Molecular Pathology/Molecular Diagnostic Toolkit." In this course, faculty members will present case studies to demonstrate the toolkit’s methodologies and technologies. Emphasis will be placed on molecular testing in the areas of clinical genetics, solid tumors, hematopathology, and infectious diseases. The application of novel technologies, such as next generation sequencing and informatics, will also be highlighted.

Note - registrants who attended the face-to-face course do not need to register for the online course to access the online materials.

CME/CMLE and SAM Credit:

How to claim credit: To earn credit, all learners must watch the lectures, achieve a minimum score of 80% on the online quiz, and complete an online survey. To access the quiz and the online survey, click "Submit credit" on the course homepage or click on "My Credit" on the menu to the left and then "submit credit" for the appropriate course.

CME/CMLE Credit

This activity was planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint providership of American Society for Clinical Pathology (ASCP) and the Association for Molecular Pathology (AMP). The ASCP is accredited by the ACCME to provide continuing medical education for physicians.

The ASCP designates this online educational activity for a maximum of 3.0 AMA PRA Category 1 Credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This continuing medical laboratory education activity is recognized by the ASCP for up to 3.0 hours of CMLE credit. ASCP CMLE credit hours meet the continuing education requirements for the ASCP Board of Certification Credential Maintenance Program (CMP) and state relicensure requirements for laboratory personnel. Participants should claim only the credit commensurate with the extent of their participation in the activity.

SAM Credit

This activity is approved by the American Board of Pathology for a maximum of 3.0 SAM Credits. Physicians should only claim credit commensurate with the extent of their participation in the activity. Participants must successfully complete the online exam (answering at least 80% of the questions correctly).

No digital files may be reproduced or transmitted in any form, by any means, electronic or mechanical. By purchasing a product, you agree to not share any of the course materials, including videos, downloadable slide presentations, outlines, manuscripts, etc. without explicit and written permission from AMP.

Course Information

Course Date:

October 31, 2018

Course Objectives

Compare and contrast a number of commonly utilized "ready out of the box" platforms with regard to their non-template amplification methodology and their clinical utilization

Enumerate several technological and clinical adaptations for PCR, non-PCR based amplification and array platforms

Discuss the methodologic and clinical considerations of when to implement testing by NGS

Compare and contrast methods of single nucleotide variant detection, copy number detection, and structural variant (fusions) detection by NGS and other related platforms (for CNVs).

Welcome and Introductions

HOT TOPICS in Molecular Diagnostics

Speaker:Kojo S. J. Elenitoba-Johnson, MD, University of Pennsylvania, Perelman School of Medicine

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