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Wine bottles come in an wide variety of sizes and shapes, which explains why label size varies so widely. The most commonly used wine bottle holds 750 milliliters. This wine bottle is considered the unofficial standard size for regular wine bottles. Bottles considered small hold 375 milliliters, and their labels measure around 2 inches by 3 inches. Large bottles carry 1,500 milliliters, and these have labels that measure around 4 inches by 5 inches.

Label size depends heavily on the shape of the wine bottle. Most bottles have an inner neck diameter of 18.5 millimeters at the mouth that increases to 21 millimeters before the body of the bottle begins.