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They're not "genetically modfied", per se. However, strains are often selected that won't go back to vegatative state easily once they've fruited. This is done with the highly skilled practice of "trial and error" ;-)

One issue with store bought is making sure you get a clean sample. Central, inner pieces of stalk work well.

-psy

--------------------It may look like a button mushroom right now, but wait until you see how it grows!

I was able to take a stem from a very fresh Portabella in the grocery store( it had some fluffy white at the base) and placed it in a container with wet cardboard. It started colonizing the cardboard with no problem. I left it growing for a few weeks, but it was during the winter and I was not prepared to go any further with it. But it is possible to get started like that.