Imbalance of these two hormones is associated with major symptoms of menopause and disorders of the reproductive system.

These symptoms are often brought into connection with a progesterone and estradiol deficiency:

In reproductive age women, an excess of estradiol relative to progesterone, known as “estrogen dominance”, can explain many symptoms including endometrial hyperplasia, pre-menstrual syndrome, fibrocystic breasts, and uterine fibroids. Perimenopausal women can also experience symptoms of estrogen dominance, which include weight gain, fibrocystic and tender breasts, uterine fibroids, irritability, and water retention. With the onset of menopause, low estradiol levels lead to hot flashes, night sweats, vaginal dryness, sleep disturbances, foggy thinking, and bone loss.

In men, too much estradiol, relative to testosterone, leads to feminizing effects such as breast enlargement and can result in a functional testosterone deficiency. The reference range for saliva estradiol is 1.3—3.3 pg/mL in premenopausal women during the luteal phase; 0.5—1.7 pg/mL in postmenopausal women; and 0.5—2.2 pg/mL in men.

How Does This Test Help?

A simple procedure of placing your saliva into the test tube is required. Once the test tube is placed, seal the sample and send the test tube to us for analysis.

Once the laboratory completes testing, the results will be sent to you within 7 working days.

This test also helps in correcting administration of medication as it produces highly reliable results, therfore; it eliminates any worries of you experiencing further illnesses or medical conditions.

This saliva testing kit is non-invasive and safe to use. The kit proves to be less expensive and hassle-free as it does not require you to book a laboratory appointment.

This test kit precisely identifies any hidden progesterone and estradiol imbalances within your body, either in deficiency or excessive form that is correlated with symptoms of menopause.

Your results will be kept confidential and your data will not be shared with any third parties.

We strongly recommend that you consult your results with your Doctor, GP and/or Health Care Provider to know whether or not any further actions need to be carried out and get started with ample treatment if it is needed.

The pack includes:

Test Requisition Form includes Symptom Checklist

Requisition Form to complete including your personal and medical history

Contains collection instructions

Vial(s) for collecting saliva

Instructions on How to Use Saliva Collection Kit

Further Reading

What is Progesterone?

Progesterone is the hormone steroid that is produced by the body which regulates menstrual cycle and it is involved with the female menstrual cycle during pregnancy. This test is specifically designed to measure your progesterone levels in order for you to know if there are any problems which are affecting you or could do so in the future regarding progesterone within your body.

What is Estradiol?

Estradiol is known to represent the major oestrogen in humans. Aside from having a critical impact on reproductive and sexual functioning, it also affects other organs in our body including the bones. It is suspected that Estradiol plays a major role in cancer of breast and uterine endometrial lining. It is unlikely to detect estradiol imbalance within the body before undergoing health checks by a Doctor, therefore it is recommended to use the saliva hormone level imbalance kit to detect any symptoms of Estradiol as this will provide beneficial results.

SALIVA TESTING

Saliva testing is used for measuring hormones like cortisol, estrogen and testosterone, and its non-invasive collection asks patients to spit into a plastic tube. This sampling method allows patients to collect saliva at home at specific times, which is important for accurately measuring hormone levels.

Why do we test hormones in saliva? Steroid hormones in the bloodstream are 95-99% bound to carrier proteins, and in this form are unavailable to target tissues. Saliva testing measures the amount of hormone available to target tissues – the bioavailable amount. For this reason, saliva testing better relates to specific symptoms of excess or deficiency, and is a good option for monitoring hormone therapy.

ZRT is one of the first labs to measure hormones in saliva, and helped establish the method that made saliva hormone testing commercially viable for health care providers and patients around the globe.

Today’s Most Advanced Saliva Testing

Ranges Adjusted for Supplementation: Unlike other labs, patients do not need to stop hormone supplementation to use ZRT’s testing because we have ranges adjusted for age, menstrual status and supplementation types. This is the ideal method for tracking the effectiveness of hormone treatments.

No Pooling: ZRT does not pool patient samples, meaning that we don’t mix multiple daily samples together to get an average hormone level. Instead we measure hormones from a single morning sample, which represents the peak of daily hormone production – the optimal time to measure.

Extraction: ZRT is the only lab to perform an extraction process for saliva testing, which separates hormones from background contamination. This is the only way to assure accurate test results for low-concentration hormones such as estradiol.

Setting Industry Standards: ZRT initiated and manages the industry-wide standards program called the Saliva Proficiency Inter-laboratory Testing Program – which enables laboratories to regularly evaluate and improve saliva testing accuracy.