Fusion

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

EFNCRP00000009596

Putative uncharacterized protein (206 aa)

Predicted Functional Partners:

5F3.050

Cysteine desulfurase, mitochondrial (505 aa)

0.971

EFNCRP00000005729

Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron- sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins (185 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

5F3.050

EFNCRP00000001040

EFNCRP00000005912

EFNCRP00000001040

Cysteine desulfurase, mitochondrial

Putative uncharacterized protein

0.969

5F3.050

EFNCRP00000005729

EFNCRP00000005912

EFNCRP00000005729

Cysteine desulfurase, mitochondrial

Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron- sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins

Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis

0.986

B11A5.190

tca-3

EFNCRP00000003863

EFNCRP00000003162

Putative uncharacterized protein

Putative uncharacterized protein

0.754

B20J13.280

B11A5.190

EFNCRP00000000532

EFNCRP00000003863

Predicted protein

Putative uncharacterized protein

0.473

B20J13.280

EFNCRP00000009596

EFNCRP00000000532

EFNCRP00000009596

Predicted protein

Putative uncharacterized protein

0.697

B20J13.280

lys-6

EFNCRP00000000532

EFNCRP00000008828

Predicted protein

Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis

0.658

EFNCRP00000001040

5F3.050

EFNCRP00000001040

EFNCRP00000005912

Putative uncharacterized protein

Cysteine desulfurase, mitochondrial

0.969

EFNCRP00000001040

EFNCRP00000005729

EFNCRP00000001040

EFNCRP00000005729

Putative uncharacterized protein

Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron- sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins

0.730

EFNCRP00000001040

EFNCRP00000009596

EFNCRP00000001040

EFNCRP00000009596

Putative uncharacterized protein

Putative uncharacterized protein

0.826

EFNCRP00000005729

5F3.050

EFNCRP00000005729

EFNCRP00000005912

Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron- sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins

Cysteine desulfurase, mitochondrial

0.994

EFNCRP00000005729

EFNCRP00000001040

EFNCRP00000005729

EFNCRP00000001040

Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron- sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins

Putative uncharacterized protein

0.730

EFNCRP00000005729

EFNCRP00000009596

EFNCRP00000005729

EFNCRP00000009596

Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron- sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins

Putative uncharacterized protein

0.971

EFNCRP00000005729

nbp-35

EFNCRP00000005729

EFNCRP00000008745

Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron- sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins