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biochem-1

biochem-1

Question 1 of 10

Process used in an expression vector to increase yield of recombinant protein synthesis ?

Select one of the following:

Translation initiation

Promoter induction

Transcription terminators

Multiple cloning sites

Question 2 of 10

1

Rothera’s test is utilised for detection of?

Select one of the following:

Glucose

Proteins

Urea

Ketone bodies

Question 3 of 10

1

Decreased energy production in thiamine deficiency is due to?

Select one of the following:

It is a cofactor for oxidative reduction

It is required for transamination reactions

It is a coenzyme for alpha ketoglutarate dehydrogenase and pyruvate dehydrogenase in citric acid cycle

It is a coenzyme for transketolase in hexose monophosphate shunt

Question 4 of 10

1

Which of the following enzymes is responsible for the transfer of amino groups from an amino acid to an alpha keto acid?

Select one of the following:

Transaminase

Transketolase

Deaminase

Lyase

Question 5 of 10

1

Site of urea cycle is?

Select one of the following:

Liver

Kidney

GIT

Lungs

Question 6 of 10

1

Which of the following is not a protein misfolding disorder?

Select one of the following:

Tuberculosis

Creutzfeldt Jakob disease

Alzheimer’s disease

Cystic fibrosis

Question 7 of 10

1

Sphingomyelinase deficiency is characteristic of ?

Select one of the following:

Fabry disease

Krabbe’s disease

Tay Sachs disease

Niemann Pick disease

Question 8 of 10

1

Xeroderma pigmentosum is produced as a result of a defect in :

Select one of the following:

DNA polymerase III

DNA exonuclease

DNA ligase

none

Question 9 of 10

1

A genetic disorder renders fructose 1,6 — biphosphatase in liver less sensitive to regulation by fructose 2,6 — bi-phosphate. All of the following metabolic changes are observed in this disorder except: