Llewelyn Moss (Josh Brolin) is out one day in the desert when he discovers a drug deal gone bad, with a pickup truck loaded with heroin and two million dollars in cash. After taking the money, a chain reaction of catastrophic violence begin to arise as he is now being pursued by a mysterious mastermind who flips coins for human lives, Anton Chigurh (Javier Bardem). He is also being pursued by Sheriff Bell (Tommy Lee Jones), who is trying to piece together the string of dead bodies that are someway connected to Llewelyn's disappearance.