Medical Xpress news tagged with:lung cellshttp://medicalxpress.com/
en-usMedical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine.Real-time imaging of lung lesions during surgery helps localize tumors and improve precisionMore than 80,000 people undergo resection of a pulmonary tumor each year, and currently the only method to determine if the tumor is malignant is histologic analysis. A new study reports that a targeted molecular contrast agent can be used successfully to cause lung adenocarcinomas to fluoresce during pulmonary surgery. This enables real-time optical imaging during surgery and the identification of cancer cells. The results are reported in The Journal of Thoracic and Cardiovascular Surgery, the official publication of the American Association for Thoracic Surgery (AATS).http://medicalxpress.com/news/2015-07-real-time-imaging-lung-lesions-surgery.html
CancerWed, 29 Jul 2015 12:34:37 EDTnews357392069How resistance to a new cancer treatment might be overcomeA promising agent for the treatment of cancer has so far had little effect on the most common lung tumours, but new research from The University of Manchester has suggested how this resistance might be overcome.http://medicalxpress.com/news/2015-07-resistance-cancer-treatment.html
CancerWed, 29 Jul 2015 08:04:17 EDTnews357375849New tool uses 'drug spillover' to match cancer patients with treatmentsTargeted therapies attack a cancer's genetic sensitivities. However, it can be difficult to discover the genetics driving a patient's cancer, and the effects of drugs designed to target a genetic abnormality often go beyond their intended target alone. The result is threefold: sometimes a drug is prescribed to treat a target that proves to be irrelevant to the disease, sometimes an existing drug could be used to treat a cancer for which there is no approved targeted therapy, and sometimes a combination of targeted treatments could be used to simultaneously silence more than one genetic cause of a patient's cancer.http://medicalxpress.com/news/2015-07-tool-drug-spillover-cancer-patients.html
CancerTue, 28 Jul 2015 17:04:42 EDTnews357321875Researchers create promising new mouse model for lung injury repairResearchers at Children's Hospital Los Angeles and The Saban Research Institute of CHLA have created a dynamic functional mouse model for lung injury repair, a tool that will help scientists explain the origins of lung disease and provide a system by which new therapies can be identified and tested. Their findings have been published online by the American Journal of Respiratory Cell and Molecular Biology.http://medicalxpress.com/news/2015-07-mouse-lung-injury.html
Medical researchTue, 28 Jul 2015 09:36:59 EDTnews357295012Cortisone affects acute lung injury (ALI) via pro-inflammatory signalling pathwaysThere's no time to lose when an emergency doctor diagnoses "shock lung" at an accident scene. What physicians know as "acute lung injury" (ALI) otherwise leads to death by suffocation without immediate treatment. This is due to water retention in the lung tissues (oedemas) and to a massive inflammatory response that, in the end, destroys lung tissues and hinders gas exchange. This acute lung injury (ALI) is treated through artificial respiration and anti-inflammatory cortisone.http://medicalxpress.com/news/2015-07-cortisone-affects-acute-lung-injury.html
Medical researchThu, 23 Jul 2015 08:22:59 EDTnews356858568Immune cells in lung cancer offer new drug targetsLung cancers attract circulating immune cells to the tumor mass, where the cancer reprograms them to support its growth and progression, researchers from Weill Cornell Medical College have found.http://medicalxpress.com/news/2015-07-immune-cells-lung-cancer-drug.html
CancerThu, 16 Jul 2015 06:19:41 EDTnews356246372Stem cells might heal damaged lungsCollectively, such diseases of the airways as emphysema, bronchitis, asthma and cystic fibrosis are the second leading cause of death worldwide. More than 35 million Americans alone suffer from chronic respiratory disease. Weizmann Institute scientists have now proposed a new direction that could, in the future, lead to the development of a method for alleviating some of their suffering. The study's findings, which appeared today in Nature Medicine, show how it might be possible to use embryonic stem cells to repair damaged lung tissue.http://medicalxpress.com/news/2015-07-stem-cells-lungs.html
Medical researchTue, 14 Jul 2015 09:45:16 EDTnews356085909Marine sponge shows tumour-stunting promiseThe research, which has been published in the highly-regarded journal Molecular Cancer Therapeutics, suggests that peloruside A—a substance produced by the marine sponge Mycale henscheli, found mostly in Pelorus Sound—has promising tumour-inhibiting properties when compared to other plant and bacterial-based agents currently used in chemotherapy.http://medicalxpress.com/news/2015-07-marine-sponge-tumour-stunting.html
CancerTue, 07 Jul 2015 07:05:42 EDTnews355471535Fishing for clues – how 'liquid biopsies' are uncovering cancer's secretsIt takes just three minutes for a precious 10 millilitre blood sample to be carried from the specialist cancer wards of the Christie Hospital in Manchester, down a corridor, and into a lab housing several large, white machines.http://medicalxpress.com/news/2015-07-fishing-clues-liquid-biopsies-uncovering.html
CancerThu, 02 Jul 2015 07:40:02 EDTnews355040254New strategies against rare, fatal lung syndromeHermansky-Pudlak syndrome (HPS) patients suffer symptoms including albinism, visual impairment, and slow blood clotting, but what makes some versions of the genetic condition fatal is that patients with some forms of the disease develop severe and progressive lung scarring. A new study explains what appears to be going wrong and demonstrates two possible therapeutic strategies in lab experiments.http://medicalxpress.com/news/2015-06-strategies-rare-fatal-lung-syndrome.html
Medical researchMon, 29 Jun 2015 16:00:05 EDTnews354794698Turning the tables on cancerIn the spring of 2012, Tom Stutz was a man without a future. Just getting through the day took all of his energy and determination.http://medicalxpress.com/news/2015-06-tables-cancer.html
CancerMon, 29 Jun 2015 06:16:01 EDTnews354777348New drug squashes cancer's last-ditch efforts to surviveAs a tumor grows, its cancerous cells ramp up an energy-harvesting process to support its hasty development. This process, called autophagy, is normally used by a cell to recycle damaged organelles and proteins, but is also co-opted by cancer cells to meet their increased energy and metabolic demands.http://medicalxpress.com/news/2015-06-drug-cancer-last-ditch-efforts-survive.html
CancerThu, 25 Jun 2015 12:00:04 EDTnews354436601Targeting nerve endings to curb allergic asthmaCurrent asthma medications, which work by suppressing inflammatory signaling by immune cells or by dilating the airways, can stop working over time. A study from Boston Children's Hospital, Brigham and Women's Hospital, and Harvard Medical School supports a surprising alternative approach to controlling asthma: targeting certain sensory nerve endings in the lungs that help drive allergic inflammation.http://medicalxpress.com/news/2015-06-nerve-curb-allergic-asthma.html
NeuroscienceThu, 25 Jun 2015 12:00:02 EDTnews354436529Cancer blocked by halving levels of protein thought to be 'untouchable'In a surprising finding, a team of UC San Francisco and Stanford University scientists has discovered that a protein thought to be crucial for the body to develop and function correctly can be reduced by half in mice with no apparent ill effects. More strikingly, the group found that the full complement of the protein normally found in cells can be hijacked by cancer cells to fuel their growth.http://medicalxpress.com/news/2015-06-cancer-blocked-halving-protein-thought.html
CancerFri, 19 Jun 2015 07:50:03 EDTnews353917416Pneumonia found to harm DNA in lung cellsA bacterium that is the most common cause of pneumonia—a leading cause of death worldwide—can damage DNA in lung cells, a new study has shown.http://medicalxpress.com/news/2015-06-pneumonia-dna-lung-cells.html
Diseases, Conditions, SyndromesTue, 16 Jun 2015 07:16:38 EDTnews353657788Breast cancer study raises hope of therapy to stop tumor spreadScientists have discovered a trigger that allows breast cancer cells to spread to the lungs.http://medicalxpress.com/news/2015-06-breast-cancer-therapy-tumor.html
CancerMon, 08 Jun 2015 11:38:41 EDTnews352982306Triple treatment keeps cancer from coming backLung cancer is the leading cause of cancer death worldwide, responsible for some 1.59 million deaths a year. That figure is due, in part, to the fact that the cancer often returns after what, at first, seems to be successful treatment. And the recurring cancer is often resistant to the chemotherapy and other drugs that originally drove it into remission. According to new research by the Weizmann Institute's Prof. Yosef Yarden, a new strategy involving a three-pronged approach might keep an aggressive form of lung cancer from returning.http://medicalxpress.com/news/2015-06-triple-treatment-cancer.html
CancerWed, 03 Jun 2015 09:39:40 EDTnews352543173Immunotherapy drug improves survival for common form of lung cancerIn a head-to-head clinical trial comparing standard chemotherapy with the immunotherapy drug nivolumab, researchers found that people with squamous-non-small cell lung cancer who received nivolumab lived, on average, 3.2 months longer than those receiving chemotherapy. Squamous non-small cell lung cancer accounts for 25 to 30 percent of all lung malignancies.http://medicalxpress.com/news/2015-06-immunotherapy-drug-survival-common-lung.html
CancerMon, 01 Jun 2015 02:50:03 EDTnews352345794Researchers taking bold steps toward engineering new lungsAccording to the World Health Organization, chronic obstructive pulmonary disease (COPD) currently affects more than 64 million people worldwide and is poised to become the third leading cause of mortality by 2030.http://medicalxpress.com/news/2015-05-bold-lungs.html
Medical researchWed, 27 May 2015 08:56:00 EDTnews351935748Novel drug combo improves function of protein underlying cystic fibrosisA novel two-drug combination has the potential to target and restore a defective protein underlying cystic fibrosis (CF), according to two phase III clinical trials conducted at 187 medical centers around the world, including Johns Hopkins.http://medicalxpress.com/news/2015-05-drug-combo-function-protein-underlying.html
Diseases, Conditions, SyndromesWed, 27 May 2015 07:30:01 EDTnews351929567E-cigarette vapor found to damage lung cells even when nicotine-freeElectronic cigarette (e-cig) use has now surpassed traditional cigarette use among middle and high school students, according to the Centers for Disease Control and Prevention. This leaves many parents, public health officials and consumers asking whether e-cigarettes are better or worse for lung health than traditional cigarettes. Now, a team of researchers adds its findings to others that suggest nicotine in any form is damaging to lungs. This new research also suggests that non-nicotine-containing e-cig solutions have a damaging effect on lung health, leading researchers to call for more e-cig research.http://medicalxpress.com/news/2015-05-e-cigarette-vapor-lung-cells-nicotine-free.html
HealthTue, 26 May 2015 08:00:02 EDTnews351844539Researchers discover molecular approach to promote cancer cell deathLung cancer researchers at Winship Cancer Institute of Emory University have discovered a novel strategy to exploit apoptosis, a form of programmed cell death, for the treatment of lung cancer. The protein Bcl-2 is a known target for cancer treatment since it allows cancer cells to evade cell death via apoptosis.http://medicalxpress.com/news/2015-05-molecular-approach-cancer-cell-death.html
CancerThu, 21 May 2015 12:00:05 EDTnews351418411Molecule designed to treat lung cancer shows promising results in miceA multidisciplinary team led by Johns Hopkins researcher Venu Raman, Ph.D., with notable contributions from Guus Bol, Farhad Vesuna and Phuoc Tran of Johns Hopkins, has identified a new therapy for lung cancer, the most common cancer worldwide. The therapy has been in development for six years and involves a first-in-class molecule designed by the team. The molecule, RK-33, interrupts the cell cycle of lung cancer cells without harming normal cells, and it is effective both on its own and in combination with radiation therapy.http://medicalxpress.com/news/2015-05-molecule-lung-cancer-results-mice.html
CancerWed, 20 May 2015 10:08:08 EDTnews351335280Lung cell phenotype reverts when seeded onto decellularized lung matrixResearchers seeded type II lung epithelial cells into a decellularized lung matrix to study their function and report the unexpected finding that instead of differentiating into type I lung cells, they instead transitioned to become mesenchymal cells, as would occur in wound healing. The design and results of this study and its implications for the development of protocols and cell culture environments to support the growth of functional lung tissue are presented in an article in Tissue Engineering, Part A.http://medicalxpress.com/news/2015-05-lung-cell-phenotype-reverts-seeded.html
Medical researchMon, 18 May 2015 11:32:42 EDTnews351167555Electronic cigarette flavorings alter lung function at the cellular levelCertain flavorings used in electronic cigarette liquid may alter important cellular functions in lung tissue, according to new research presented at the 2015 American Thoracic Society International Conference. These changes in cell viability, cell proliferation, and calcium signaling are flavor-dependent. Coupling these results with chemicals identified in each flavor could prove useful in identifying flavors or chemical constituents that produce adverse effects in users.http://medicalxpress.com/news/2015-05-electronic-cigarette-flavorings-lung-function.html
HealthSun, 17 May 2015 19:23:43 EDTnews351109414Experimental immunotherapy shows high response rate in advanced lung cancerAn early phase study testing an anti-PDL1 agent in combination with standard chemotherapy in the treatment of advanced non-small cell lung cancer has provided promising early results, prompting multiple phase III studies in lung cancer. The findings are being presented at the annual meeting of the American Society of Clinical Oncology (ASCO).http://medicalxpress.com/news/2015-05-experimental-immunotherapy-high-response-advanced.html
CancerThu, 14 May 2015 10:46:18 EDTnews350819169Scientists are able to take immortality from cancerScientists from the Spanish National Cancer Research Centre (CNIO) have discovered a new strategy to fight cancer, which is very different from those described to date. Their work shows for the first time that telomeres—the structures protecting the ends of the chromosomes—may represent an effective anti-cancer target: by blocking the TRF1 gene, which is essential for the telomeres, they have shown dramatic improvements in mice with lung cancer.http://medicalxpress.com/news/2015-05-scientists-immortality-cancer.html
Medical researchWed, 13 May 2015 07:01:19 EDTnews350719237New blood tests, liquid biopsies, may transform cancer careA new type of blood test in the U.S. is starting to transform cancer treatment, sparing some patients the surgical and needle biopsies long needed to guide their care.http://medicalxpress.com/news/2015-05-blood-liquid-biopsies-cancer.html
CancerMon, 11 May 2015 09:49:14 EDTnews350556544Scientists look at links between HAP and lung infections including pneumoniaScientists at LSTM have come a step closer to understanding why people exposed to household air pollution (HAP) are at higher risk of lung infections such as pneumonia and tuberculosis.http://medicalxpress.com/news/2015-05-scientists-links-hap-lung-infections.html
Diseases, Conditions, SyndromesFri, 08 May 2015 09:05:12 EDTnews350294705Finding points to a cause of chronic lung diseaseScientists have long suspected that respiratory viruses—the sort that cause common colds or bronchitis—play a critical role in the long-term development of chronic lung diseases such as asthma and chronic obstructive pulmonary disease (COPD).http://medicalxpress.com/news/2015-04-chronic-lung-disease.html
ImmunologyTue, 21 Apr 2015 07:25:24 EDTnews348819914