News

2009/05/08 COFECO was published at Nucleic Acids Reserch. access2009/02/10 It supprots twenty-one model ogranisms and twenty-seven identifiers. more2008/10/18 Version 1.0 was released.

What is COFECO?
COFECO is a web-based tool for a composite annotation of protein complexes, KEGG pathways, and Gene Ontology (GO) terms within a class of genes and their orthologs under study.

What are the COFECO functionalities?(1) Employment of protein complexes as an annotation resource: the composite annotation sets of correlated functions and cellular processes for a given gene set can be identified in a more comprehensive and specified way by the employment of protein complex data together with GO and KEGG pathways as annotation resources.
(2) Comparative analysis with orthologs: orthology based integrative annotations among different species complement the defective annotations in an individual genome, and provide the information of evolutionary conserved correlations.
(3) Specified composite annotation via term filtering: a term filtering feature enables users to collect the specified annotations enriched with selected function terms.
(4) Cross comparison between the annotation outputs: a cross-comparison of annotation results between two different datasets is possible.
(5) Summarization and exploration of annotated functions via graphical views: COFECO provides a web-based GO hierarchical viewer and KEGG pathway viewer where the enrichment results can be summarized and further explored.