Infected over night.

Ive posted this problem on another forum but the person helping seems to have given up.
(http://forums.techguy.org/security/470637-pc-infected-over-night.html#post3645009) I really need my pc back in good health asap. When I tried scanning with the online scanners none of them wanted to start. Ive ran ad-aware, microsoft anti-spyware, spybot S&D, system mechanic, spy sweeper and Im currently running ewido. everything before ewido has found things but just doesnt seem to fix the problem completely. As for ewido the siren is going crazy. I wish I could reformat but theres WAY to much stuff on here I need to keep. I tried system restore but every time I pick a date to roll back to it says the restore was unable to rollback to that date. So this is my last hope in getting this intruder off my system. It seems that this place has alot more know-how.
Anyway heres my HJT log:

--verbose hjt removed--

I have a ewido log but it doesnt want to post on here so let me know if you want it.

Im not sure why you posted telling me to read the first post as I had already done so. As for the HJT log being an attachment I must have misunderstood. I thought it was only the ewido log that had to be an attachment, sorry for the hickup.

ok so now that Ive done everything required in the post ill post my newest HJT log here.I cant seem to fix this thing on my own even after all the scans and fixs. I still hear the clicking sounds and sometimes get a little error message from IE at random ( I do use firefox ) the link at the very top of this thread shows what I had done before coming here and all that did was make it so I dont see the pop-ups. they still minimize my games and I still hear the clicking coming from them, Not to mention the voice recoded pop-ups that now I cant close myself. Also Ive found that if i take all my icons of the desktop i cant see my wallpaper and theres a small white dot in the upper left hand corner.
Heres my hjt log, hopefully someone can tell me whats going on and help me to fix this >_<:

Well I did what you said and actually scanned twice just to be sure. Then I reebooted and scanned again. I had a look at it and the things I had just selected and fixed in hjt before in safe mode are back and still causing problems.
I wont post the hjt log since its the same thing as above.

Well I Ended up reformating since nothing was getting rid of this. Even so I wanted to come back ehre and thank both for trying to help me with this situation. So thanks. I wish I had seen your last post before doing so but I guess a fresh start is better in this matter since I had many security leaks.
Is there anything you could suggest to further protect my system other than the guide in this forum?