But when asked by presenter Sarah Montague whether there were any family traditions which needed to be explained to the American, the 33-year-old Prince said: “Oh plenty. I think we’ve got one of the biggest families that I know of, and every family is complex as well.

“No look, she’s done an absolutely amazing job. She’s getting in there and it’s the family I suppose that she’s never had.”

Meghan’s mum and dad Doria and Thomas divorced when she was six and she once revealed to pals she was “not on the best of terms” with her reclusive father.

Prince Harry appeared to be happy with the way his radio show was going

But Harry’s comments were leapt upon by Meghan’s sister Samantha Grant last night.

Samantha, 52 - who suffers from multiple sclerosis - wrote on Twitter: “Actually she has a large family who were always there with her and for her.

“Our household was very normal and when dad and Doria divorced, we all made it so it was like she had two houses.

“No one was estranged, she was just too busy. Meg’s family (our family) is complete with sister, brother, aunts, uncles, cousins and the glue of our family, our amazing completely self-sacrificing father.