Around 700m viewers in 200 different countries will tune into the big Premier League showdown.

The fixture has a history of distasteful baiting over the tragedies the clubs suffered at Munich and Hillsborough.

United lost eight players and members of staff in the 1958 air crash in Germany while 96 Liverpool fans lost their lives at the Sheffield stadium disaster in 1989.

But Mourinho has pleaded for the supporters to cut out the negative chants.

“In football we have some football tragedies, if you can speak of them like that, which is the big match we lost, some mistake a player did and you can make fun of that in some way,” said the United manager.

Read More

“But the human tragedy is something much more serious, and I think is the last thing somebody should use in a football pitch, because they were really big tragedies.

“So I would be really sad if in such a big football match that was a negative point.”

Earlier in the week United and Liverpool joined forces to issue a statement to the fans attending Monday's fixture on Merseyside.

In a joint statement, the clubs said: “Both clubs, their supporters and football fans around the world are looking forward to this historic and passionate match between two of the sport’s biggest and oldest rivals.

“There is great rivalry between our fans and we ask all supporters to be respectful and help eradicate all forms of offensive and discriminatory behaviour from the game.”