established from the bone marrow of a 31-year-old woman with acute myeloid leukemia (AML FAB M5a) at 2nd relapse; described in the literature to show strong lysozyme activity in the cytoplasm, phagocytic activities, and cells are responsive to induction of differentiation with TPA; cells carry the t(9;11)(q23;p22) KMT2A-MLLT3 (MLL-MLLT3; MLL-AF9) alteration

Species:

human (Homo sapiens)

Tissue:

N/A

Disease:

acute myeloid leukemia

Gender:

N/A

Morphology:

single round cells growing in suspension;

Growth Mode:

N/A

Doubling Time:

ca. 35 hours

DNA Profile:

N/A
Cobioer’s Cell Line Authentication Service

Culture Medium:

RPMI1640+10%FBS
We strongly suggest to purchase the complete medium from Cobioer.

This line was initiated in 1972 by D.J. Giard, et al. through explant culture of lung carcinomatous tissue from a 58-year-old Caucasian male. Cells were described to induce tumors in athmyic mice and to synthesize lecithin.