How Cannabis Works for Chronic Pain and The Best Strains

Research reports that cannabis is as effective as opioids for chronic pain. In this post from Medical News Today, find out what are the best strains for relief from chronic pain and how do they work.

Medical marijuana is an increasingly popular alternative to traditional pain-relieving medications, including opioids. Marijuana may ease certain types of chronic pain, including pain resulting from nerve damage and inflammation.

It is, however, important to note that this study had several limitations. It was small in scale, anonymous, and asked people to self-report on their symptoms. Respondents did not use the marijuana in a controlled setting, potentially resulting in differences in drug composition, dosage, and potency.

Another study examined the use of organically grown sativa and indica strains in the treatment of several medical conditions. Just over half of the participants were using marijuana to treat HIV.

The study followed participants for 3 years and asked them about the effects of the drug on their condition during this time. The results indicated that indica strains are more likely to improve energy and appetite, while both sativa and indica strains can alleviate nausea to a similar degree.

How does marijuana work for pain?

Marijuana, or cannabis, contains compounds that may relieve pain, nausea, and other symptoms. The components of marijuana that most studies focus on for pain relief are cannabidiol (CBD) and tetrahydrocannabinol (THC).

THC vs. CBD

THC resembles the cannabinoid chemicals that occur naturally in the body. When people ingest or inhale THC, it stimulates the brain’s cannabinoid receptors.

This activates the brain’s reward system and reduces pain levels. THC is a psychoactive compound as it binds to cannabinoid receptors and produces an elevated state of mind, known as a high.

CBD does not cause a high, although it does interact with pain receptors in the brain to exert pain-relieving and anti-inflammatory effects.

What the research says

In recent years, many studies have looked at the effects of marijuana for chronic pain.

A 2015 review of research on the use of marijuana for various chronic pain conditions reports that several trials had positive results. The researchers suggest that marijuana or cannabinoids may be effective for treating some types of chronic pain including neuropathy (nerve pain).

A research paper from 2016 found that marijuana use for chronic pain led to a 64 percent reduction in opioid use, improved quality of life, and caused fewer medication side effects. It also led to participants using fewer medications.

Smaller studies have reported benefits for other types of chronic pain. For example:

Of about 17,000 people with cancer, 70 percent reportedly experienced an improvement in pain and general well-being after marijuana use.

People with chronic migraines experienced a decrease in migraine episodes after using the drug.

However, there is still a need for more research into the area of marijuana use for chronic pain, especially into the use of different strains, dosages, and methods of delivery.

Synthetic marijuana

Medical marijuana refers to the whole, unprocessed plant or its extracts. Medical marijuana is not approved by the U.S. Food and Drug Administration (FDA) as a safe or effective treatment for any condition.

However, the FDA have approved medications containing synthetic THC cannabinoids called dronabinol (Marinol) and nabilone (Cesamet). These drugs reduce nausea in people undergoing cancer treatments and increase appetite in people living with HIV.

Ongoing clinical trials are also investigating the use of drugs containing CBD for the treatment of childhood epilepsy.

The FDA have not yet approved the use of any synthetic marijuana drugs for pain relief.

Alternatives to herbal marijuana

Oil

It is possible to extract full extract cannabis oil (FECO) from cannabis using grain alcohol or ethanol.

People usually take FECO orally and should only need small quantities to experience benefits.

CBD is another type of marijuana-based oil that is increasingly popular among people with chronic pain.

Topical treatments

People can apply lotions, balms, and salves containing cannabinoids to the skin to relieve pain and inflammation. Transdermal patches that contain cannabinoids are also available and are typically more potent than lotions and salves.

Edibles

Edibles are one of the most popular ways to use marijuana. Edibles involve infusing food, such as cookies, brownies, and candies, with the drug.

Marijuana edibles offer an easy way to take marijuana, but the effects of edibles can be difficult to predict.

Sublingual cannabis

Sublingual administration involves placing a drug under the tongue. The drug enters the bloodstream faster using this method and so it will work more quickly.

Marijuana vs. opioids for pain relief

Some research has suggested that marijuana is as effective as opioids for chronic pain relief.

Opioids are powerful medications that relieve pain by acting on the nervous system. They are highly addictive, and withdrawal symptoms are not uncommon.

In 2016, approximately 116 people died every day in the U.S. from opioid-related drug overdoses, and 11.5 million people misuse prescription opioids every year.

Is marijuana better than opioids?

Medical marijuana may offer an alternative to addictive opioids. When researchers surveyed almost 3,000 medical cannabis users, they found that 30 percent had used opioids in the last 6 months.

Of those respondents, 81 percent agreed or strongly agreed that marijuana was more effective alone than in combination with opioids.

In addition, 97 percent said they agreed or strongly agreed that they could decrease their opioid usage when taking marijuana.

Takeaway

Several studies report the benefits of marijuana use for chronic pain.

According to some research, it is as effective as opioids, which are among the most potent pain-relieving drugs.

The side effects of marijuana use are usually minimal, especially in comparison with opioid side effects.

This evidence indicates that marijuana may be beneficial for chronic pain relief.

There are several strains of marijuana available, so even if one strain does not reduce symptoms, another may. Typically, it is best for people to keep their dosage low, especially if they are new to using marijuana.

Those who wish to use medical marijuana should discuss the risks and benefits in more detail with their doctor.