Ex Vivo Tension Recording

The DMT 620M Wire Myograph™ system is used to conduct ex vivo vascular ring tension recording on multiple vessel types including the aorta, the pulmonary artery and the middle cerebral artery. The highly sensitive, flexible system can accommodate vessels down to 100 μm in diameter. Relaxation and contractile activity are measured using force transducers. The system:

Allows ex vivo study of compound activity on vascular function

Enables assessment of antagonist potency for receptor/agonist combinations in both naïve and diseased model tissues