Gene Link provides a rapid purification system for extraction of viral DNA or RNA from human bodily fluids including blood. Viral DNA or RNA is captured on a special membrane and then eluted in a low volume for direct use in qualitative and quantitative amplification protocols for detection of a pathogen. The Viral RNA purification system is ideal for small volumes of human bodily fluid samples, i.e., serum, plasma and CSF. Using the easy spin column format, purification of HIV, HCV and other RNA viruses is easily accomplished in less than 30 minutes and ready for RT-PCR amplification.