Dr. Alexander W. Peterson

Research Interests:

Enhancing the capabilities of surface plasmon resonance (SPR) spectroscopy. The major interests of my research are to: 1) make SPR more quantitative, 2) develop SPR as an imaging tool, 3) combine SPR imaging with other techniques such as fluorescence and phase contrast microscopty, 4) apply SPR imaging to other areas such as cellular imaging and measure cell features as well as extracellular protein deposition, and 5) design a hybrid microscope that incorporates fluorescence microscopy with SPR microscopy. The combination of these orthogonal and complementary methods will allow benchmarking and confirmation of interpretation of the SPR imaging results.

Illustration of the SPR image analysis procedure to quantify protein deposition at the periphery of smooth muscle cells.

Brief slide show about high resolution surface plasmon resonance imaging of single mammalian cells: