P53-Regulated Apoptosis-Inducing Protein 1 (TP53AIP1) ELISA Kits

TP53AIP1 is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. Additionally we are shipping TP53AIP1 Antibodies (43) and TP53AIP1 Proteins (3) and many more products for this protein.

large sample size of the combined cohort rejects a high-risk effect greater than 2.2 and indicates a limited role of TP53AIP1 in prostate cancer predisposition

p53AIP1 regulates the mitochondrial apoptotic pathway.

The expression of Ki67 (show MKI67 ELISA Kits) and p53 (show TP53 ELISA Kits) in various forms of leukoplakia point to the increasing instability of the genome in parallel with the severity of leukoplakia.

expression of the p53 (show TP53 ELISA Kits) mutant, R248Q, in liver cancer cells may enhance their drug resistance and upregulation of P-glycoprotein activity may contribute to this protective effect.

Roscovitine induced up-regulation of p53AIP1 protein and the depolarization of mitochondrial potential.

p53AIP1 gene is important for non-small cell lung cancer progression and may be a possible prognostic marker

Insufficient expression of p53AIP1 may play a role in gastric carcinogenesis in patients infected with H. pylori infection.

TP53AIP1 Antigen Profile

Antigen Summary

This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.