Two little girls were held hostage in their Queens home last night while their mother was abducted and taken on a terrifying high-speed ride by kidnappers trying to escape pursuing cops, police said.

The kids, ages 3 and 5, were later found unharmed, and the chase ended with the arrest of two of the suspected kidnappers, one of whom jumped into the Hudson River in a failed bid to get away, police sources said. The woman, 24, was unharmed.

The sources said they suspect the abduction was drug-related.

Cops said the drama unfolded at about 11 p.m. when two suspects, described only as Hispanic men, got into the house on 124th Street in College Point by pretending to be cops. They took the woman and fled a Nissan Quest.

A third suspect stayed behind with the woman’s children, cops said.

The fleeing van was spotted as it crossed the Triborough Bridge into Manhattan by cops who followed it to the Henry Hudson Parkway. There, the van clipped three other vehicles at West 155th Street.

It was finally stopped at the West 79th Street boat basin, where one of the suspects jumped into the water but was captured shortly afterward.

The second suspect was taken in for questioning.

The children, who had been taken by the third suspect, were found unharmed at Jamaica Avenue and the Van Wyck Expressway. The third suspect is still at large, cops said. The names of the victims were not released.