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Molecular recognition and binding of ligands (atoms, ions, and molecules) by proteins with high sensitivity and selectivity is of central importance to essentially all biomolecular processes and of key importance for the basic and applied sciences. In Pro...

Much of the recent spectacular progress in the biological sciences can be at­ tributed ot the ability to isolate, analyze, and structurally characterize proteins and peptides which are present in cells and cellular organelles in only very small amounts. R...

This book provides a survey of topics, in the area of innate and adaptive immunity, which have been researched within the MRC Immunochemistry Unit, at Oxford University, over a period of forty years. The topics include: antibody structure, for which the f...

Membrane Proteins - Production and Function Characterization a volume of Methods in Enzymology, encompasses chapters from the leading experts in the area of membrane protein biology. The chapters provide a brief overview of the topics covered and also ou...

This book presents advanced expression technologies for the production of protein complexes. Since complexes lie at the heart of modern biology, the expression, purification, and characterization of large amounts of high-quality protein complexes is cruci...

The majority of all proteins undergo posttranslational modifications that significantly alter their physical and chemical properties, including their folding and conformation distribution, their stability, and, consequently, their activity and function. I...

To date, virus-encoded homologs of G protein-coupled receptors (GPCRs) have been discovered only in members of the poxvirus and herpesvirus families. The herpesvirus members have been more extensively characterized than the poxvirus members, but all were ...

This text offers in-depth perspectives on every aspect of protein structure identification, assessment, characterization, and utilization, for a clear understanding of the diversity of protein shapes, variations in protein function, and structure-based dr...

Recent major advances in our understanding of modulating protein functions has led to the development of new methods and algorithms to predict and decipher how amino acid sequences shape three-dimensional structures. Protein Design: Methods and Applicatio...

Solving Problems in Food Engineering is a step by step workbook intended to enhance students' understanding of complicated concepts and to help them practice solving food engineering problems. The book covers problems in fluid flow, heat transfer, mass tr...

Although cytotoxic chemotherapy is very effective in the management of certain neoplasms such as testicular cancer, the efficacy of this therapeutic modality in the treatment of many common neoplasms is limited. Cure of macroscopic metastatic disease is e...

Understanding and predicting the behaviour of natural and human environmental systems is crucial for the effective management of the Earth’s limited resources. Recently, great advances have been made through spatial modelling. This book provides a snapsho...

Traditionally spectral methods in fluid dynamics were used in direct and large eddy simulations of turbulent flow in simply connected computational domains. The methods are now being applied to more complex geometries, and the spectral/hp element method, ...

This book provides a state-of-the-art review of a major recent technology which has now reached a level of maturity. The editors have pioneered the development and application of these techniques and technologies, and the chapter authors are leading pract...

In magnetic systems of nano-meter size, the interplay between spin and charge of electrons provides unique transport phenomena. In magnetic superlattices, magnetic and non-magnetic metallic thin films with thickness of the order of one nano-meter are pile...