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Presence of colistin resistant bacteria in the gut of human body

Recently, scientists found indirect evidence of colistin-resistant bacteria in the gut of the human body.

About the colistin resistant bacteria

Presence in poultry and vegetables:The team of scientists found that colistin-resistant Klebsiella bacteria were widely present in poultry and raw vegetables.

Reasons:

The main cause of colistin resistance in food is due to the rampant use of colistin in poultry.

Since poultry litter is used as manure to grow vegetables, colistin-resistant bacteria are found in vegetables as well.

What causes the resistance? In clinical practice, it is the mutation in the mgrB gene or other chromosomal genes that confers colistin resistance to Klebsiella bacteria.

Problems:

Scientists noted that colistin resistance due to mutation in food Klebsiella has the potential to spread to human Klebsiella in the gut and hence may contribute to colistin-resistant infections in humans.

It is found that a huge number of individuals carry colistin-resistant bacteria of food origin in the gut is therefore worrying.

About Colistin:

Colistin is the last-resort antibiotic used to treat highly drug-resistant bacterial infections.

Colistin-resistant bacteria can be of hospital origin or food origin.

Colistin-resistant bacteria of hospital origin do not respond to any of the antibiotics, including carbapenem while colistin-resistant bacteria of food origin will respond to carbapenem.

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