Datasheet Extract

Immunogen

Immunogen:

N-terminal extracellular domain of human

Background

The growth hormone secretagogue receptor (GHSR) is a Releasing-Hormone Receptor for growth hormone-releasing peptides as well as non-peptide, low molecular-weight secretagogues. Ghrelin, a gastric peptide, has been identified as a ligand for GHSR, indicative of its role in appetite control. GHSR is regulated by thyroid hormones. There are two splice variants of GHSR. GHSR has been reported to be expressed primarily in brain and pituitary. Various other tissues, including colon, gastrointestinal tract, kidney, lung, placenta, stomach, thyroid, and vessel, express GHSR.