Maxwell lived in London for many years, and now resides in Kent with his wife, whom he married in 2015, and their three children. He supports Scottish football team Hibernian F.C. - although on the 12th March 19, in a green van, he was overheard to claim allegiance to Liverpool[3]

Other credits for Maxwell include RI:SE as the United States correspondent, a regular guest slot on a weekly topical comedy-style chat show The Panel which ran on Irish TV channel RTÉ One from 2003 until 2011, and regular appearances on British TV shows Never Mind the Buzzcocks and Mock The Week. He appeared on the Secret Policeman's Ball in 2006, while a Funny Cuts special for E4, called Andrew Maxwell – My Name Up In Lights aired that same year. In 2014, Maxwell appeared in Comedy Central's Drunk History and was the narrator of Ex on the Beach, an MTV reality based television series. Maxwell has narrated every series since the show's launch. In October 2018, Maxwell appeared in the Irish episode of HISTORY's TV series Al Murray: Why Does Everyone Hate The English alongside host Al Murray. Maxwell has also appeared on the BBC Radio 4 series "The News Quiz".

Maxwell was voted the "King of Comedy" on the Channel 4reality TV show of the same name. In 2007 he was nominated for the if.comedy award for the best show at the Edinburgh Fringe.