Living successfully eleven years after weight loss surgery.

February 17, 2012 posts

These adorable cupcake necklaces are handmade by one of my BBGC members, made from rolled bottle caps with a design inside that reads "I heart cupcakes", complete with the cherry on top! The design has a lacquer finish inside for durability.

The chain is a dog-tag style "ball chain" that is about 11.5 inches long. It comes in your choice of several colors: black, gold, red, pink, blue, green and purple.

Sure, it can can work to help you lose weight, but your heart gets cranky and you forget what you were blogging about. The FDA says the effects can get worse over time. Super.

Did I mention that although I couldn't feel my feet or remember my underwear -- I heart Topamax? Because, since I quit taking it? I have gained weight. And, what's this about getting worse over time -- I -- still can't remember anything.

Food and Drug Administration staff will ask an advisory panel to consider whether the drug's benefits for obese patients will outweigh its risk of birth defects and heart problems.

The FDA staff, in documents posted online on Friday, said patients taking Qnexa during a clinical trial lost more weight, and kept it off for longer, than patients taking a placebo, or sugar pill. These patients also had lower levels of problems associated with obesity, such as issues with blood pressure and blood sugar.

However, the FDA staff said patients taking the drug had more safety problems than patients on a placebo, including memory loss, and these problems could get worse over time. They also said exposure to one of the ingredients in Qnexa has been linked to a higher rate of birth defects in other studies.

Shares of Vivus rose 2.4 percent to $11.45 in pre-market trading.

An advisory panel of outside experts will vote Feb. 22 on whether to recommend the drug, and the FDA is due to make its final decision by April 17.

Qnexa is a combination of appetite suppressant phentermine and anti-seizure drug topiramate.

A company study in December showed topiramate caused a higher rate of oral clefts in infants of women taking the drug during pregnancy, and the company said it would limit Qnexa to women who are not pregnant.

The FDA already rejected Qnexa in 2010 because of safety concerns -- including elevated heart rate in some users and the potential for birth defects if pregnant women used the drug.

Vivus resubmitted its application in October, proposing to limit the drug to only women who cannot have children. In January, the company broadened the label to just limit pregnant women from taking the drug, in response to an FDA request.