Application Information: OTUD5 antibody

1
mg/ml
(Please refer to the vial label for the specific concentration)

Purification

Affinity chromatography purified via peptide column.

Specifications: OTUD5 antibody

Full Name

OTU domain containing 5

Product Description

Rabbit Polyclonal antibody to OTUD5

Background

This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008]

Synonyms

OTU domain containing 5 Antibody , DUBA Antibody

Host

Rabbit

Clonality

Polyclonal

Target

OTUD5

Isotype

IgG

Immunogen

OTUD5 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of the human OTUD5.

Antigen Species

Human

Species Reactivity

Human, Mouse

Conjugation

Unconjugated

Storage Conditions: OTUD5 antibody

Storage Buffer

PBS containing 0.02% sodium azide.

Storage Instruction

Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Notes

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

OTUD5 antibody validated data

GTX31361 WB Image

Western blot analysis of OTUD5 in human kidney lysate with OTUD5 antibody at (A) 1 and (B) 2 ug/mL.