A Pilot Study of Effects of Exenatide on Body Weight in Non-Diabetic, Obese Patients

Official Title ICMJE

A Pilot Study of Effects of Exenatide on Body Weight in Non-Diabetic, Obese Patients

Brief Summary

This is a multicenter study designed to compare the effect of exenatide plus a lifestyle modification plan versus placebo plus a lifestyle modification plan on weight loss in non-diabetic, obese subjects.

Have ever participated in this study previously, or any other study using exenatide (AC2993/LY2148568) or GLP-1 analogs

Have participated in an interventional medical, surgical, or pharmaceutical study (a study in which an experimental, drug, medical, or surgical treatment was given) within 30 days of study start (this criterion includes drugs that have not received regulatory approval for any indication at the time of study entry)

Diagnosis of diabetes mellitus (other than gestational diabetes), or previous use of anti-diabetic medications for > 3 months

Have had a change in prescribed lipid-lowering or blood pressure agents within 4 weeks of screening