III.J.19. Medical
Countermeasures for Encephalomyelitis Viruses. Develop
medical countermeasures against the biological warfare threat
of the encephalomyelitis viruses, a group of viruses that
cause disorientation, convulsions, paralysis, and death.
Vaccines will protect 80 percent of the immunized population
against an aerosol exposure of the virus and will induce
minimum reactogenicity in soldiers when immunized. By FY96,
transition to development an improved vaccine effective
against Venezuelan equine encephalomyelitis (VEE) virus
stereotypes 1 A/B/C. By FY98, construct analogous vaccines
for Eastern equine encephalomyelitis (EEE) and Western equine
encephalomyelitis (WEE). By FY00, develop a multivalent VEE
vaccine that includes serotypes 1E and III.

Supports: Army
Modernization Plan Objectives, Medical Annex OProject,
Sustain, and Protect the Force by Development of NBC Agent
Preventive Measures. Provides for the exploration,
demonstration, and validation of biological defense vaccines
as outlined by the DEPSECDEF (26 Aug 91) and the Joint
Requirements Oversight Council (31 Aug 92).