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We have established a clinical pancreatic islet cell transplantation program within the Centre and act as part of the UK Islet Tranplant Consortium funded by Diabetes UK. This team also work on a research program that explores ways of improving islet survival after transplantation with the goal of improving transplant efficiency and efficacy. On-going work examines the mechanisms of revascularisation of transplanted islets and the role of hypoxic injury.