I am debating between the two, I know that Media Engine is made with car computer in mind and MyHTPC is probably made more for a home theathre setup.

Pros on Media Engine: The interface is great and works great with touchscreen. Very nice looking. And is soon to support GPS software, soon to support search.
Cons on Media Engine: Can't use plugins, there are alot of programs that I don't need such as the fm on. (can it be removed?) And the worst thing about it, cannot que songs!

MyHTPC: Don't know too much about it except you can que songs in a playlist. Does it support touchscreen? Can I use gps software with it?