Lika is the most notable example of a periphery and also the most problematic region in Croatia. This work represents research into the region’s demographic development under the conditions of Croatia’s polarized development up to the beginning of the 1990s and the wartime and postwar events during the last intercensus period. The spatial scheme of analysis adheres to the sub regions and contemporary local government units. The results show that Lika and all of its sub-regions were beset by demographic devastation already during the 1980s. In the current period, it is characterized by extremely inauspicious demographic features, which seriously brings into question the possibility of revitalizing this region.