Genetic Control of Immune Response and Susceptibility to Infectious Diseases

Call for Papers

Susceptibility to and control of infectious diseases are multifactorial, dynamic, and phenotypically diverse. Both genetic and nongenetic variables can influence them. Knowledge about roles of genetic variations seen in host immune response genes comes mainly from population genetics of candidate genes through interindividual susceptibility association studies. The observed interindividual variation is due, in part, to risk-modifying polymorphisms (rare and common) in agonist and antagonist genes of the innate and adaptive immune responses. The mechanisms that underlie the observed interindividual variation in control/resistance/susceptibility are not completely understood. We invite investigators to contribute original research articles as well as review articles that will advance the knowledge and stimulate research efforts to understand the basis of genetic control of immune response and susceptibility to infectious diseases. Potential topics include, but are not limited to: