Win32.Vitro & ISO Images

before i start i posted this same question in the Malware area of the forums almost 3 days ago and have had no response at all. i need to know if Win32.Vitro can infect iso images, i read on a google-found forum that it can infect exes INSIDE compressed zip/rar files. but by my logic it shouldnt be able to. if anyone can answer this you will be saving me ALOT of grief and time