Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Disease

hereditary spherocytosis

Age

5 years

Gender

male

Ethnicity

Caucasian

Applications

The cells are resistant to 6-thioguanine and can be used in fusions with human B lymphocytes to produce human hybridomas.

Disclosure

This material is cited in a US or other Patent and may not be used to
infringe the claims. Depending on the wishes of the Depositor, ATCC may be
required to inform the Patent Depositor of the party to which the material was
furnished. This material may not have been produced or characterized by ATCC.

Karyotype

modal number = 48; Y present

Clinical Data

male

Caucasian

5 years

Genes Expressed

immunoglobulin; monoclonal antibody (small amounts)

Cellular Products

immunoglobulin; monoclonal antibody (small amounts)

Comments

The cells are resistant to 6-thioguanine and can be used in fusions with human B lymphocytes to produce human hybridomas.

The cells have a high cloning efficiency in soft agar and by limiting dilution.

This material is cited in a US or other Patent and may not be used to
infringe the claims. Depending on the wishes of the Depositor, ATCC may be
required to inform the Patent Depositor of the party to which the material was
furnished. This material may not have been produced or characterized by ATCC.

Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.