Certolizumab is an injectable synthetic (man-made) protein that blocks the effects of tumor necrosis factor alpha (TNFα), therefore, reducing symptoms of arthritis (fever, pain, tenderness, and swelling of joints) and and symptoms of Crohn's disease (fever, abdominal pain, and diarrhea).

What does Cimzia treat?

Cimzia is used for treatment of severe Crohn’s disease and rheumatoid arthritis. It may be used alone or combined with methotrexate or other non-biological rheumatoid arthritis drugs. It has also been studied for treating psoriatic arthritis.

How effective is Cimzia?

Crohn’s disease

35% of Cimzia treated subjects compared to 27% that received placebo responded after 6 weeks

37% of Cimzia treated subjects compared to 27% that received placebo responded after 26 weeks

29% of Cimzia treated subjects compared to 18% that received placebo were in remission after 26 weeks

Rheumatoid arthritis

46% of Cimzia treated subjects compared to 9% that received placebo had clinical response after 24 weeks of treatment