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"Clubbing" of the fingers is one of the features of Cystic Fibrosis, although not present in many patients

Author Jerry Nick

https://en.wikipedia.org/wiki/Cystic_fibrosis

health problems with Cystic Fibrosis

Author Bruce Blauswikimedia commons

https://en.wikipedia.org/wiki/Cystic_fibrosis

health problems with Cystic Fibrosis

Author Bruce Blauswikimedia commons

https://en.wikipedia.org/wiki/Bronchoconstriction

Burkholderia multivorans

General information

the following information is not yet verified
Several Burkholderia species have been isolated from human clinical samples, but only Burkolderia cepacia complex, B. gladioli , B. mallei and B. pseudomallei are generally recognized as human pathogens.

Natural habitat They are found in water and soil and can survive for prolonged periods in moist environments. These bacteria can act as a powerful pesticide, capable of eliminating many soil-borne plant pathogens.

TransmissionB. cepaciacomplex is highly transmissible between cystic fibrosis patients and can be transferred from one CF patient to another in hospitals, health clinics, and social environments.

They are a significant risk factor for morbidity and mortality in CF.

Clinical significanceB. cepacia complex has long been recognized as an occasional opportunistic human pathogen, capable of causing a variety of infections, including bacteremia, urinary tract infection, peritonitis, and pneumonia in persons with underlying illness.

Like cystic fibrosis (CF), they are particularly susceptible to infection.

Cystic fibrosis is a genetic, life-threatening disorder that primarily affects the digestive system and the lungs.

It is a most common potentially lethal autosomal recessive disease.

Strains of B. cepacia complex are frequently associated with aggressive pneumonia that is accompanied by rapidly fatal bacteremia.(cepacia syndrome)

Culture characteristics

McConkey growth Colonies of the B .cepacia complex frequently become dark pink to red due to oxidation of lactose after extended incubation (4-7 days)

BBAØ no growth

BCSA (B. cepacia selective agar) It may take 3 days before the colonies are seen from respiratory tract specimens from CF patients. Colonies are smooth and slightly raised; occasionally isolates are mucoid.