Ayahuasca: Adverse Events Evaluation

A recent review has evaluated the existing evidence of adverse reactions to ayahuasca – a hallucinogenic brew, used for religious or medicinal purposes, traditionally from the Northwestern Amazon region. The assessment of reports of severe intoxications due to the intake of ayahuasca or its alkaloids suggests that most cases can be traced back to pre-existing hepatic or cardiac conditions and/or concomitant use of other serotonergic drugs/medications; and that caution should be exercised with the use of botanical species not traditionally used or synthetic analogues of the alkaloids contained in ayahuasca.

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