The short and long term results with two multidrug regimens were compared in 40 untreated lepromatous, case. The drug combination investigated were (a) rifampicin, clofazimine and DDS and (b) rifampicin, prothionamide INH and DDS. There was good improvement in patients in both the groups, but no additional benefit was obtained in t he form of (1) quickly reaching the point of no infectivity (when compared with the trials involving use of rifampicin alone) and (2) the frequency of persistors at the end of two years. No serious side effects were encountered.

Clinico-pathological features of seven patients of subcutaneous phycomycosis are described .The, ages of the patients ranged from 1 1/2 years to 6 years. Four patients were males and females.. The sites of involvement included leg, thigh, buttock, shoulder, upper arm, thorax and abdominal wall. Three patients had itching in the lesions and three patients were having fever. In five patients fungal elements were demonstrated on histopathological examination. The causative fungu, - Basidiobolus haptosporus was grown from four patients. All the seven patients responded to potassium iodide therapy.

Treatment of Non-specific Urethritis in Males with Demeclocycine Hydrochloride

p. 249

DD Ganguli, JA Sundharam, NC Bhargava, Ravi Nigam

Fifty patients with non-specific urethritis were treated with demeclocycline hydrochiloride in doses of 600 mg and 900 mg respectively per day for three weeks. The cure rates obtained were 90% and 88% respectively. The side effects included stoeaatitis one; nausea, vomiting and diarrhoea in 5; and phototbyicity in two cases.

Clinical Profile and Response to Chemotherapeutic Agents in Non-specific Urethritis

p. 252

RK Pandhi, AS Kumar, DA Satish, RA Bhujwala

The epidemiological and clinical profile of 159 patients having non-specific iiretbritis is repoed. The majority (67.39o) of patients were unm and most (70.4%) of the we m re in the age group of 21-30 years. The incubation period in the majority (69.2%) of patients was 1-4 weeks. Almost all the (98.1%) patients complained of dysuria but urethral discharge was seen only in 48.4% of patients. Out of tetracycline's doxycline, erythromycin and cotrimoxazole tried in this study, tetracycline's in the dosage of 2 gm/day for 3 weeks was found to give the best (90.5%)'cure rate.

A young man having congenital annular constrictions of the legs with lymph-oedema of the left foot below the constriction, webbing of the fingers of both hands, anonychia of two fingers and intrauterine amputation of terminal phalanges of two finger and one big toe is reported.

A 10 year old girl developed recurrent non-itchy, skin coloured umbilicated papules along with scrofuloderma in the left inguinal region, and constitutional disturbances. A quick response to antitubercular treatment a highly positive Mantoux test and the histopatholpgical findinits suggest that the papular lesion were an atvvical tuberculid.

A case of rare variant of squamous cell carcinoma which merits the name of epithelioma cuniculatum occurring on the palm is being reported. Association of hereditary palmo-planter keratoderma is highlighted.

A one and a half month old infant with kerion,,tinea faciei and tinea corporis starting at the age of 3 days is reported because of its rarity. An incubation period of three days was noticed in this case.