The whole point of the Ultimate universe seemed to be to take all of Marvel's already dysfunctional characters and turn them into complete monsters. In the end it may have been more about mirroring the writer(s)'s warped psyche than anything else. As such, it's probably likelier that the twins will be snaking off into the bushes in Fox's movies than anywhere else since Millar is supposedly a consultant over there.

The whole point of the Ultimate universe was shock value. They figured the only way to sell comic books in the 21st century was through shock and auggghh.