Powers:A biochemical genius, Monica is one of the world's foremost authorities on organic toxins. Her inventions include the enhanced lymphatic system of the A.I.M. waker agents that granted them total immunity to all biological, chemical and radiological weapons; memetic antibodies, synthetic microbes that attack the human psyche and trigger pre-coded memories and impulses; hallucinogenic drugs that deliver programmed hallucinations before being absorbed into the system; and many innovative weapons of mass destruction, from gas attacks to nanobacteria bombs. Rappaccini's A.I.M. uniform belt contains a phasing device that allows her to teleport short distances.

Bio:While enrolled as a biochemistry student at the University of Padua, Monica Rappaccini went to New Mexico's Desert State University to study and shared a brief relationship with Bruce Banner, a physics student who would later become the Hulk. The ruthless Monica used their relationship to exploit Banner's radiation expertise for her own research. Upon attaining her doctorate, Monica quickly became a world-renowned innovator of anti-toxins and antidotes for various environmental poisons and nearly won the Nobel Prize.

Recognizing the many environmental and political failings of Western Civilization, Monica decided it was too corrupt to exist. She joined a series of terrorist organizations - first the pan-European leftist group Black Orchestra, then Advanced Idea Mechanics (A.I.M.), where she had a brief relationship with fellow agent George Tarleton (later MODOK). Now making poisons instead of curing them, Monica's expertise with toxins allowed her to rise quickly through A.I.M.'s ranks. She implanted her own daughter and several other newborn children of A.I.M. members with memetic antibodies and released them into the world as A.I.M. waker agents with no knowledge of their heritage, programmed to travel instinctively to the nearest A.I.M. biohaven when their antibodies activated at age 16. Monica's daughter was raised in Vermont as Carmilla Black by undercover A.I.M. agents.

Monica went underground for nearly two decades, studying potential power sources as the sentient Uni-Power and orchestrating attacks on capitalism, such as the dioxin-based gas attack on Hong Kong. When the A.I.M. Scientist Supreme was slain by his own renegade creation, MODOK, Monica became head of the splinter faction of A.I.M. that remained independent from MODOK's control. Following M.O.D.O.K.'s numerous defeats, Monica's splinter group absorbed more cells into a sizable rival faction, and she was made Scientist Supreme of this "true" A.I.M.. As A.I.M. leader, Monica rarely did field work, preferring to act through agents and proxies.

When she recently led an A.I.M. attack on the United States Army Medical Research Institute for Infectious Diseases, it was thwarted by her estranged 19-year old daughter, who had since joined forces with S.H.I.E.L.D. and became the costumed Scorpion. Rappaccini eluded capture and soon attempted to harness the malfunctioning Uni-Power, but her plans were thwarted by Scorpion and several heroes who bonded with the Uni-Power.

Her A.I.M. faction was involved in an A.I.M. civil war that drew in Ms Marvel and SHIELD, following Ms Marvel's thwarting of a plan to turn M.O.D.O.K. into a psychic bomb, Rappaccini reunited the organisation under her control.

Monica and A.I.M. were next seen in the MODOK's 11 mini-series, having infiltrated MODOK's supervillain gang with their new Ultra-Adaptoid robot (which is impersonating the Chameleon). She is attempting to prevent MODOK from obtaining the Hypernova weapon and erasing all life on Earth. She has a stated aim to stop A.I.M. creating "inventions that turn around and try to destroy us". By the end of the series, MODOK had gained the Hypernova and Monica gave him a billion dollars in exchange for it - which had been MODOK's plan all along, as he'd worked out the Hypernova would grow unstable and explode. AIM's base was destroyed in the explosion and MODOK believes Monica is dead, though this has not been confirmed (the base was evacuating at the time, and Rappacini does have access to teleportation technology).