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This is an authoritative and comprehensive vision of molecular cell biology. Advances in our knowledge of how cells work has driven the discipline to the point where we understand the cell at new levels of complexity such as larger signalling complexes in cells, and cells interacting with other cells. To present this new view of molecular cell biology and the accompanying advances in experimental technology, the fifth edition shows exciting developments in cell birth, lineage and death expanded coverage of signalling systems within the whole cell/organism and expanded coverage of metabolism and movement of lipids. In addition, new pedagogy includes research questions by looking at real experimental data in "analysing the data" problems and "updated perspectives for the future" at the end of each chapter, which explore potential applications of future discoveries and unanswered questions that lie ahead for researchers. The media package includes a companion website with animations, videos and classic experiments covering groundbreaking molecular cell biology experiments to enhance student learning. For instructors there are PowerPoint images from the text solutions and a test bank. Other supplements include an instructor's CD-ROM containing all text images, a conversion guide from the 4th edition test, bank animations and videos, and overhead transparencies. And for students there is the "Working with Molecular Cell Biology, Fifth Edition: A Study Companion and Solutions Manual".

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Reseña del editor

This is an authoritative and comprehensive vision of molecular cell biology. Advances in our knowledge of how cells work has driven the discipline to the point where we understand the cell at new levels of complexity such as larger signalling complexes in cells, and cells interacting with other cells. To present this new view of molecular cell biology and the accompanying advances in experimental technology, the fifth edition shows exciting developments in cell birth, lineage and death expanded coverage of signalling systems within the whole cell/organism and expanded coverage of metabolism and movement of lipids. In addition, new pedagogy includes research questions by looking at real experimental data in "analysing the data" problems and "updated perspectives for the future" at the end of each chapter, which explore potential applications of future discoveries and unanswered questions that lie ahead for researchers. The media package includes a companion website with animations, videos and classic experiments covering groundbreaking molecular cell biology experiments to enhance student learning. For instructors there are PowerPoint images from the text solutions and a test bank. Other supplements include an instructor's CD-ROM containing all text images, a conversion guide from the 4th edition test, bank animations and videos, and overhead transparencies. And for students there is the "Working with Molecular Cell Biology, Fifth Edition: A Study Companion and Solutions Manual".

Biografía del autor

HARVEY LODISH is Professor of Biology at the Massachusetts Institute of Technology and Member of the Whitehead Institute for Biomedical Research. - ARNOLD BERK is a world-famous Virologist at the University of California, Los Angeles. - PAUL MATSUDAIRA is a Member of the Whitehead Institute for Biomedical Research, Professor of Biology and Bioengineering, Massachusetts Institute of Technology, and Director of the WI/MIT BioImaging Center. - CHRIS A. KAISER is Professor of Biology and teaches genetics at the Massachusetts Institute of Technology. - MONTY KRIEGER is the Thomas D. & Virginia W. Cabot Professor in the Department of Biology at Massachusetts Institute of Technology. - MATTHEW P. SCOTT is a member of the National Academy of Sciences and teaches Developmental and Disease Mechanisms to medical students, and Developmental Biology to graduate students at Stanford University. - LAWRENCE ZIPURSKY is a Professor of Biological Chemistry and an Investigator of the Howard Hughes Medical Institute in the School of Medicine at the University of California, Los Angeles. - JAMES DARNELL is a member of the National Academy of Sciences, Vincent - Astor Professor and Head of the Molecular Cell Biology Laboratory, The Rockefeller University.

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Amazon.com:
3,9 de 5 estrellas
35 opiniones

James Turner

5,0 de 5 estrellasUsed this book as text for course

4 de junio de 2002 - Publicado en Amazon.com

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I used this book as the text for a UC Santa Cruz extension course in molecular cell biology. I read about 2/3 of it for course reading assignments and I found it to be excellent. It's clearly and well written but is definitely information dense. You really have to focus closely while you're reading it. Expect to need to read most sections at least twice to absorb the material.The diagrams are plentiful, are well drawn and must also be studied carefully since they contain information not included in the body of the text itself.Information has obviously been updated as new versions of the book have appeared. This 4th edition has many references to publications as recent as 1999.The animations in the accompanying CD are sometimes useful. A good example is the animation in chapter 22 of cell-cell adhesion in leukocyte extravasation.

I just repurchased this 4th edition after realizing that the later editions of Molecular Cell Biology have damped down on biophysical and biochemical aspects of cell biology; much of the equations have been removed from this classic textbook in the later editions. It is a common problem across most biochemistry and cell-biology texts these days - it only serves to dumb-down the current generation of graduate students.

This is a very comprehensive book about molecular cell biology. It starts from the very basics of chemistry and protein, and ends with a very clear molecular description of cell cycles and cancer. I wouldn't recommend it as a textbook for someone who's just learning the basics, especially if it is for a class, since the amount of information is sometimes too much to handle.

Pros:1- Extensive coverage of most major topics in cell biology.2- Impressive level of detail, down to the function of the secondary structures in proteins.3- Very interesting explanations about how things were discovered.4- Each chapter section is divided into points. The authors show you how every point was proved. For example, to tell you vesicles need this protein to bind to other membranes, they tell you that some biologist created mutants that were lacking this protein and noticed that the vesicles were formed but were unable to bind, and a reference is present at the end of the chapter.5- Small summaries at the end of each section.6- Kept really up to date. Current articles in Nature & Science magazine usually take over where this book left off.

Cons:1- There are some exercises at the end of each chapter, but they're too simple to be of any value to you except reviewing the high level concepts. There is only one "Analyzing the Data" exercise which brings some value. If you haven't memorized every single protein, you can always flip back a few pages and read off the name that you're looking for. The study guide that comes with it also doesn't have very much information. You can look at their website online but will only find multiple choice questions. The Alberts book + study guide on the other hand, does give you about 100 exercises per chapter, and that really helped me understand certain concepts.2- The book is nearly a thousand pages long and it is presented in two-column, small font mode. I found that it took me several hours to read through a single chapter.3- Somewhat inconsistent writing. Some chapters adopt a very narrative description that is smooth and easy to read. Other chapters just name every single protein involved and through a disordered approach expect you to put things together. Not to mention many of the proteins have the same prefix but different numbers at the end "Tom40, Tom22, Tom76". Such data would look much better tabulated.

I like this book. There's a good amount of content, accompanied with excellent illustrations. However, the organization is pretty bad -- instead of describing processes such as transcription in a natural sequence, the authors jump around from one thing to another, making it hard to find things. The index isn't comprehensive enough, either.one more caveat: my Cell Phys professor, who's a botanist, complained about the lack of coverage of plant cells, and he's right.

Even though I am a mathematician and not a biologist, I absolutly love reading like this book. I read 'The Cell' when it came out in the early 80s. It was a life changing experience. The diagrams alone in these texts tell a wonderful story. I bought 'Molecular Cell Biology' to compare with The Cell. Both books are wonderful. I would hate to say what a low price I paid for my used copy. It's worth more than 10 times that amount. To me such books are a treasure! They are priceless.