Major conference topic: "Biomedical Engineering of Dynamical Systems"

40th International JVE Conference on Dynamics of Biological Systems is an integral part of Vibroengineering Series
Conferences and will be held in Kaunas, Lithuania.
Internationally renowned invited speakers and contributing authors from all over the world will present the latest advances in the
field of Biomedical Engineering of Dynamical Systems.
This conference will feature a broad range of high-level technical presentations including invited distinguished experts.

The conference will provide an opportunity to communicate your recent research advances, exchange ideas in innovative Biomedical Engineering technologies,
meet old friends and make new business partners in Biomedical Engineering. With your participation, this Conference will be an exciting scientific event,
a fruitful opportunity to promote scientific research and technological development of Biomedical Engineering and its applications.

The conference is organized by JVE International with the partnership of Lithuanian University of Health Sciences,
Kaunas University of Technology, Vytautas Magnus University, Vienna University of Technology (Austria),
Silesian University of Technology (Poland), Hohai University (China),
Barcelona University (Spain) and HeartMath Institute (USA).

Fast track surgery and the surgical approach to heal chronic wounds - even with the indication for amputation - are examples in
which the auricular vagus nerve stimulation plays a crucial role. Basic knowledge about the effects of the auricular vagus stimulation and
the associated clinical studies will be presented.

New approaches in medicine: Endobiogeny-integrative physiology and systems analysis in the clinic

Endobiogeny is a theory of complex global systems analysis and integrative physiology. It was developed by physicians to
assist medical decision making. Serum biomarkers are considered to be the downstream output of global upstream neuroendocrine regulators of metabolism.
They are related through a combinatorial process, then algorithmically analyzed. This approach allows for a dynamic, integrated, interrelated and holographic
approach to the human being at multiple scales of function. At microscopic biological scale, cellular processes can be evaluated. At the mesoscopic
physiologic scale, tissue, organ and global organismic function can be evaluated. At the macroscopic phenomenological scale, psychological, social,
and symbiotic tendencies, and, response to chronobiologic, geomagnetic and cosmobiologic demands can be evaluated. The system offers clinicians the
ability to observe the evolution on the patient in response to interventions across space and time. This offers a new approach to precision and
personalized medicine based on the organism’s expressed phenotypic capabilities for auto-regulation, rather than latent genetic possibilities.

Multimodal in vivo imaging in preclinical evaluation of medical interventions in stroke (and its context in the digital society)

The critical step in the preclinical evaluation of envisaged medical interventions (new drugs, stem cell applications, electroceuticals) is testing them on
the laboratory animals. In case of the ischemic stroke, a clinically relevant animal model is middle cerebral artery occlusion (MCAO). Due to the complex
cascade of events after brain ischemia, longitudinal follow up of stroke consequences is a crucial element, and it is enabled through assessing the
morphological and molecular parameters by the in vivo imaging.
In our research, we use magnetic resonance imaging (7T Bruker MRI) and bioluminescence imaging (optical imager Perkin Elmer IVIS Spectrum) to follow
up the animals up to 28 days after ischemic brain lesion. The dedicated collection of transgenic animals carrying luciferase reporters enables to get
insight in neuroinflammation (Tlr2-luc/GFP transgenic mouse), axonal repair (Gap43-luc/GFP transgenic mouse), and apoptosis (caged-luciferin bioluminescence
imaging). Each modality is informative individually, but we could show that using multimodal approach and standardizing the bioluminescence according to
the MRI measurements enhances the detection of the significant changes among tested animal groups. In case of mice with Tlr2-deficiency, which exhibits
modified neuroinflammation after ischemic lesion, the in vivo imaging revealed the enhanced elements of brain repair but as well prolonged and increased
apoptosis.
The stroke, being a major health problem, is in need to be addressed through innovative approaches in order to help the patients and protect the
healthy ones. The digital society being global and immediate generates both benefits and risks for the individuals expecting to be treated and cured
by current advances of medical technologies. I would argue that translating the logic of the offline environment can create the confusion and impasses
in the online context. The complexity of the digital geometries distort online space and time, having as a consequence disruption of the medical
regulations and the risky individual trajectories in a search for health. The navigation through digital knowledge landscapes appears to be a key
element of the person-centered health care.

This study proposes a stent motor as a medical device. A stent is a medical instrument
inserted in a constricted part of a blood vessel to expand the blood vessel. However, the problem
is that plaque accumulates around the installed stent and causes the blood vessel to narrow again.
A stent motor is used to remove plaque. A stent motor consists of a receiver part to receive
ultrasonic vibration and a stator part to drive the motor in the blood vessel. The purpose of this
study was to develop a stent motor and determine its optimum design. It was possible to drive a
stent motor by subjecting a disk-shaped receiver to strong ultrasonic vibrations. Experiments were
performed on the stent motor with several types of receivers by changing their size and shape,
and the efficiency was evaluated. Correlation between the design of the stent motor, such as the
number of turns in the stator and the shape of the receiver, and the rotational speed was clarified.

The Brain as a Dynamic System: A bottom-up perspective on cognitive processes underlying food intake regulation

Maintenance of energy homeostasis, i.e. the balance between caloric intake and energy expenditure, has to be maintained in a tight range
to ensure health and survival. Throughout evolution, a sophisticated neuronal network has developed that integrate various streams of
information from the body about energy availability. This network enables us to adapt a wide range of behavioral and autonomic responses
to precisely control food intake, energy expenditure, and substrate flux across different peripheral organs. Dysregulation of the underlying
homeostatic circuits causes prevalent diseases, such as obesity and type-2 diabetes mellitus, which are on an epidemic rise in industrialized societies.
At the example of regulation of food intake behavior, I discuss how the brain processes external sensory and internal homeostatic signals
to initiate –dynamically– behavioral and physiological responses. Here, a focus will be on circuit-level models of metabolic mechanisms.
In this regard, emphasis will be on those biological pathways that mediate individual differences in behavior and risk for (psycho-)pathology
implicated in the control of body weight and energy homeostasis. Accordingly, I explore the role of reward processing and motivated behavior
in obesity and related disorders.

This Conference is accredited by Center of Excellence of Healthcare and Pharmacy Specialists for medical doctors, healthcare specialists, psychologists and nursing specialists. Accreditation is for 8 hours.

Important Dates and Fees

Paper submission

already closed

Decision (accept, revise or reject)

in two weeks after submission

One Author registration fee:

Early Bird (Until May 31)

250 EUR

Regular (After May 31)

350 EUR

Listener's Registration fee:

Regular

119 EUR

For Baltic Countries and Poland

65 EUR

Listener's registration deadline until

September 25, 2019

Principal topic of the conference is Biomedical Engineering of Dynamical Systems and other topics are also included in the conference agenda.

Modelling, Simulation and Control (topics related to biomedical engineering)

Biomathematics

Biomedical Computing

Simulation in Biomedicine, Sports and Ergonomics

Control of Complex Processes in Biology

Biomechanics

Bone and Joint Engineering

Musculoskeletal Modelling and Tissue Mechanics

Physiotherapy and Sports Biomechanics

Prosthetics and Orthotics

All papers presented at International JVE Conference will be published as short Conference papers in Vibroengineering Procedia.
Conference papers published in Vibroengineering Procedia is indexed in Scopus, EI Compendex, Inspec, Gale Cengage, Google Scholar and EBSCO.

Authors of papers presented at International JVE Conferences are invited to extend their manuscripts to full journal papers which
will be considered for publication in one of our Open Access journals:

Conference program will be announced shortly after submission deadline.

Submission and Registration fees

Paper submission is already closed.

Decision (accept, revise or reject) in two weeks after submission

Submission

Your manuscript should be submitted online via JVE Journal Management System (JMS) https://manage.jvejournals.com.
Using the JMS requires an account. You can create a new account by following the 'Create an account' link that appears on the main login page. The signup process only
takes a minute – we don't need many details from you. Once you've created your account or signed in, you're ready to submit a manuscript:
Submit manuscript.

Your manuscript should be uploaded in Microsoft Word and Adobe PDF formats. Note that if your manuscript is accepted for publication, the manuscript will be reprocessed by JVE team.
But to start with, manuscript format should conform the Paper Template. Before submitting your
manuscript to the JVE Conference please ensure that the manuscript is 4-6 pages long.

Venue

Conference Venue will take place in Lithuanian University of Health Sciences.

Sukilėlių pr. 15, Kaunas 50103, Lithuania

Sponsors and Partners

Conference in Kaunas, Lithuania is organized by JVE International in partnership with Lithuanian University of Health Sciences,
Kaunas University of Technology, Vytautas Magnus University, Vienna University of Technology (Austria), Silesian University of Technology (Poland),
Hohai University (China), Barcelona University (Spain) and HeartMath Institute (USA).

For more information, inquiries, sponsorship requests or any other co-operation interests, please Contact Us