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Hmm Arakawa stated in an Interview that Homunculi don't need to sleep or eat, but do so as much as possible because it would consume some of their stone otherwise. So my guees would be they aren't generally immune to it, but they heal their illnesses automatically, so they don't really get sick.

question 2 (ages as of the final arc. Might be off by one year on some counts):

Spoiler:

Ed: 16
Al: 15
Hohenheim: 400-450
Father: 400-450
Trisha: 26 (at time of death)
Hughes: 29 (at time of death. He and Roy were the same age)
Roy: 30
Winry: 16 (same age as Ed)
Sara and Urey Rockbell (Winry's parents): 29 and 35 respectively when they died
Marcoh: Mid 50s
King Bradley: 60
Grumman: early 60s-ish
Hawkeye: A few years younger than mustang, so probably 25-28

Yeah, that spot was just outside Amestris. Because if you recall the country's shape isn't exactly round, it misses the upper part, so to complete the circle they must take a step outside of the country's territory.

Is it ever explained why Ed can't repair his own automail with alchemy even if it's only partially damaged? I mean, wouldn't it just be a process of analysising its composition and memorising how it's made?

Is Fullmetal Alchemist Brotherhood a remake or something ?Because I've seen the first episodes and all they do is show episodes I've seen in the first season...

Like the flashback of their childhood,and that charlatan that made everyone believe that he can create miracles...

The first 15 or so episode follow the same material as the first series, but after that is goes in another direction. I would recommended to still watch those first 15 episodes because their are some small changes that are important later on.

Brotherhood follows the whole mange unlike the first series. The first series was awesome, but Brotherhood tops it easily.