Operation

Powered by a 12g disposable CO2 cartridge or re-fillable internal air system, it features a blowback design and 9 shot capacity magazine using .43 caliber paintballs or rubberballs. The trigger is double-action (DA/SA). First versions did not have a conventional on/off safety. Current versions now have a manual trigger-lock safety. The marker is cocked by working the slide and there is also a functional de-cocker. It differs from the RAP4/5 system as it does not use (and therefore) eject shell casings. Muzzle velocity is adjustable between 200ft/s and 300ft/s. For .43 cal paintball - 0.029 oz it is about 3.4371 J (at 300ft/s).

Use

The RAM P99 looks, feels and shoots with great accuracy just like the Walther P99 firearm making it ideal for law enforcement and military training, especially close quarter battles and room clearings. The RAM P99 is also used for virtual reality paintball play.

Rap1

Rap1 (Ras-proximate-1 or Ras-related protein 1) is a small GTPase, which are small cytosolic proteins that act like cellular switches and are vital for effective signal transduction. There are two isoforms of the Rap1 protein, each encoded by a separate gene, RAP1A and RAP1B. Rap1 belongs to Ras-related protein family.

GTPases are inactive when in their GDP-bound form, and become active when they bind to GTP. GTPase activating proteins (GAPs) and guanine nucleotide exchange factors (GEFs) regulate small GTPases, with GAPs promoting the GDP-bound (inactive) form, and GEFs promoting the GTP-bound (active) form. When bound to GTP, small GTPases regulate myriad cellular processes. These proteins are divided into families depending on their protein structure, and the most well studied is the Ras superfamily, of which Rap1 is a member. Whereas Ras is known for its role in cell proliferation and survival, Rap1 is predominantly involved in cell adhesion and cell junction formation. Ras and Rap are regulated by different sets of guanine nucleotide exchange factors and GTPase-activating proteins, thus providing one level of specificity.

Rap6

RAP6 is the abbreviation for Rab5-activating protein 6, a novel endosomal protein with a role in endocytosis. RAP6 was discovered by Alejandro Barbieri and his group of researchers (Christine Hunker, Adriana Galvis, Ivan Kruk, Hugo Giambini, Lina Torres and Maria Luisa Veisaga) working at Florida International University.

The original GeneBank Identifications (GIs) have been published in the NCBI Nucleotide databases with GIs 77176718 and 77176720. Since then, many names have been coined to the validated protein such as RabGEF1, GeneID: 27342. RAP6 belongs to the family of the GAPVD1, GeneID: 26130

References

External links

Roma Symphony (Bizet)

The Symphony in C "Roma" is the second of Georges Bizet's symphonies. Unlike his first symphony, also in C major, which was written quickly at the age of 17, Roma was written over an eleven-year span, between the ages of 22 and 33 (he died at age 36). Bizet was never fully satisfied with it, subjecting it to a number of revisions, but died before finishing his definitive version. All four movements were performed in his lifetime, but never all on the same occasion. The full symphony in its latest revision was premiered in 1875, after his death. It is perhaps because of Bizet's dissatisfaction that the work is often said to be "unfinished". However, in the form in which it exists today, it is a complete work and is fully scored. It has been recorded a number of times but is not often heard on the concert platform.

Background

Bizet won the Prix de Rome in 1857, which required him to spend the following two years studying free of charge at the French Academy in Rome, followed by a year studying in Germany. He never went to Germany, but stayed in Rome until July 1860. Rather than returning to Paris straight away, he did some touring through Italy, seeing places he had not visited in his earlier travels in 1858 and 1859. In Rimini he first planned a symphony with each of the four movements dedicated to a different Italian city – Rome (opening movement), Venice (Andante), Florence (Scherzo) and Naples (finale). He may have made some early sketches at this time. When he got to Venice he learned that his mother was seriously ill, so he returned home immediately.

The series features a sprawling ensemble cast of characters, many of whom are based on real figures from historical records, but the lead protagonists are ultimately two soldiers, Lucius Vorenus and Titus Pullo, who find their lives intertwined with key historical events. Rome was a ratings success for HBO and the BBC. The series received much media attention from the start, and was honored with numerous awards and nominations in its two-series run. Co-creator Heller stated in December 2008 that a Rome movie was in development, but as of early 2015 no further production had been initiated. The series was filmed in various locations, but most notably in the Cinecittà studios in Italy.

Operation

Powered by a 12g disposable CO2 cartridge or re-fillable internal air system, it features a blowback design and 9 shot capacity magazine using .43 caliber paintballs or rubberballs. The trigger is double-action (DA/SA). First versions did not have a conventional on/off safety. Current versions now have a manual trigger-lock safety. The marker is cocked by working the slide and there is also a functional de-cocker. It differs from the RAP4/5 system as it does not use (and therefore) eject shell casings. Muzzle velocity is adjustable between 200ft/s and 300ft/s. For .43 cal paintball - 0.029 oz it is about 3.4371 J (at 300ft/s).

Use

The RAM P99 looks, feels and shoots with great accuracy just like the Walther P99 firearm making it ideal for law enforcement and military training, especially close quarter battles and room clearings. The RAM P99 is also used for virtual reality paintball play.