Pantoprazole

Drug Levels and Effects:

Summary of Use during Lactation:

Limited information indicates that maternal pantoprazole doses of 40 mg daily produce low levels in milk and would not be expected to cause any adverse effects in breastfed infants.

Drug Levels:

Maternal Levels.

A mother who was 10 months postpartum and partially nursing her infant was given a single 40 mg dose of oral pantoprazole. Pantoprazole was detectable in milk only 2 and 4 hours after the dose with milk levels of 36 mcg/L and 24 mcg/L, respectively, at those times. It was not detectable (<10 mcg/L) in milk at 6, 8 and 24 hours after the dose. The authors estimated that a fully breastfed infant would receive 0.14% of the maternal weight-adjusted dosage.[1]

Alternate Drugs to Consider:

References:

Substance Identification:

Substance Name:

Pantoprazole

CAS Registry Number:

102625-70-7

Drug Class:

Anti-Ulcer Agents

Administrative Information:

LactMed Record Number:

409

Last Revision Date:

2012-10-02

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