The Role of Herpes Simplex Virus Type 2 and Other Genital Infections in the Acquisition of HIV-1 Among High-Risk Women in Northern Tanzania

From CDC National Prevention Information Network

May 18, 2007

In the current study, investigators examined the role of herpes simplex virus type 2 (HSV-2) and other genital infections on HIV-1 incidence in a cohort study of female hotel/bar workers in Moshi, Tanzania, from 2002 to 2005.

Among 845 HIV-negative participants at the study's start, researchers interviewed and collected blood and genital samples from 689 (81.5 percent) at baseline and at every three months for a total of 698.6 person-years at risk (PYARs). Predictors of HIV-1 incidence were evaluated using a Cox proportional hazards regression model.

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