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Holzman was born in Bronxville to the late Edward and Charlotte Walsh and grew up in Mount Vernon. She worked as an administrative assistant for March of Dimes. On Feb. 6, 1965, she married the late Richard Holzman at St. Francis of Rome in the Bronx.

She was a mother, grandmother known as "Nana" and treasured her relationships with her brothers, their families and her cousins. She maintained lifelong friendships and loved celebrating holidays with families and friends. She was a devout Catholic and attended services at Our Lady of Sorrows Church.

She is survived by two children Richard (JoAnne Wills) Holzman of Baltimore and Deborah (Steven) Beaudrot of Milford, Mass.; grandchildren Maggie and Joseph Holzman of Baltimore and Steven, Charlotte, Brendan and Kaitlyn Beaudrot of Milford; and her brother, Robert (Margaret) Walsh, and sister-in-law Patricia Walsh.