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Human Gene Nomenclature

Harriet S. Meyer

The International System for Human Gene Nomenclature (ISGN) was inaugurated in 1979, and has been continually updated. The Human Gene Mapping Nomenclature Committee, which developed the ISGN, put forth a “one human genome one gene language” principle: Certainly there exists a genetic and molecular basis for a single human gene language without dialects. All human nuclear genes as we know them follow the same genetic, molecular, and evolutionary principles…. Thus it is reasonable and logical to develop a standard and consolidated gene nomenclature system rather than have a human gene language based on different gene systems.(p12) The committee, known as

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