Definition

Alternative Names

Causes

Acromegaly is a rare condition. It is caused when the pituitary gland makes too much growth hormone. The pituitary gland is a pea-sized endocrine gland located at the base of the brain. It controls, makes, and releases several hormones, including growth hormone.

Usually a noncancerous (benign) tumor of the pituitary gland causes the gland to release too much growth hormone.

In children, too much growth hormone causes gigantism rather than acromegaly.

Treatment

Surgery to remove the pituitary tumor that is causing this condition often corrects the abnormal growth hormone. Sometimes the tumor is too large to remove completely. People who do not respond to surgery may have radiation of the pituitary gland.

Medications are used after surgery. Some patients are treated with medicines instead of surgery.

After treatment, you will need to see your health care provider regularly to make sure that the pituitary gland is working normally. Yearly evaluations are recommended.

Support Groups

Outlook (Prognosis)

Pituitary surgery is successful in most patients, depending on the size of the tumor and the experience of the surgeon.

Without treatment, the symptoms will get worse. Conditions such as high blood pressure, diabetes, and heart disease may result.

Possible Complications

When to Contact a Medical Professional

Call your health care provider if:

You have symptoms of acromegaly

Your symptoms do not improve with treatment

Prevention

Acromegaly cannot be prevented. Early treatment may prevent complications of the disease from getting worse.

Version Info

Last reviewed on 11/7/2013

Brent Wisse, MD, Associate Professor of Medicine, Division of Metabolism, Endocrinology & Nutrition, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Bethanne Black, and the A.D.A.M. Editorial team.

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