The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.

Comments

Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.

Number of paths to term:

24

denotes an 'is-a' relationshipdenotes a 'part-of' relationshipdenotes a 'regulates' relationshipdenotes a 'positively-regulates' relationshipdenotes a 'negatively-regulates' relationship