Introduction

BindingR is a database for Saccharomyces cerevisiae protein-protein
interaction binding sites at an aggregate aspect combining domain-domain,
domain-motif, and motif-motif levels. It provides users with a web-based
interface for fast and convenient access to all potential binding sites of a
given interacting protein pair at the three levels.

Background

Proteins usually carry out their functions in a cell by interacting with other molecules such as DNAs, RNAs, and other proteins. Interacting proteins more often contact each other by a domain binding to another domain, by a domain binding to a short protein motif, or by a motif binding to another motif. These predicted binding site pairs at the aggregate level should behelpful for the understanding of the mechanism of protein-protein interactions and be insightful into protein functions, diseases and genomic evolution.

Description

The BindingR database
contains the binding sites at the three levels of motif-motif, motif-domain,
and domain-domain for Saccharomyces cerevisiae protein-protein interactions.
We provide users with four search features for fast and convenient access to
binding sites at three levels of protein interactions and potential
interacting partner of a domain or motif.