A nationally televised night game to officially christen and present $1.2 billion Levi's Stadium will also do wonders for the 49ers' offense. The big question then is how the new sod reacts. Prediction: Win

Another long roadie -- their fourth road game in six weeks -- proves to be more bountiful than their previous three. Eli Manning keeps throwing passes, and the 49ers keep picking them off. Prediction: Win

They had to cancel the preseason series between these two Bay Area rivals because of fan violence in San Francisco. So what happens on Pearl Harbor Day in Oakland? Raiders give Niners a scare. Prediction: Win

Week 15: at Seattle Seahawks

Seattle has not been a nice place for the Niners, who have lost their past three games at CenturyLink Field by a combined score of 94-33. Make it four straight. Prediction: Loss

By this time, it will have been almost four months since the Chargers' first-team defense abused the Niners' starters on offense and Philip Rivers shredded the 49ers' first-team defense. These will be different teams now, right? Prediction: Win

Week 17: Arizona Cardinals

The 49ers will be in full stride now, either trying to wrap up the NFC West or a wild-card spot. At home, they are simply too much for the much-improved Cardinals to close out the regular season. Prediction: Win