Anthropogenic green house gas emissions are leading to increases in global temperature and have negative consequences in many parts of the world. South Asia is particularly at risk. Ecological zones such as the Himalayas, the arid plains and extensive coastal zones have high levels of direct exposure to the impacts of climate change. In addition, populations across the region are highly vulnerable. Many live in regions that already face the direct impact of floods, droughts and extreme storms. At the same time, many depend on climate-vulnerable livelihoods such as agriculture and fishing, and lack the financial and other resources essential to adapt. Minimizing the impact of climate change on vulnerable populations and vulnerable regions within South Asia requires understanding both the natural dynamics of the systems affected by climate change and the functioning of human institutions. This publication presents twenty-two brief analytic pieces on climate science, shared learning process,vulnerability assessment, communication and ecosystems that contribute to such understanding. The pieces are based on research undertaken by a consortium of organizations working across South Asia.