My Vision Test

A free modern Amsler Grid test for Macular Degeneration

MyVisionTest News Archive

May 27, 2008

Supplemental lutein and fish oil increases macular pigmentA new study published in the current edition of the American Journal of Clinical Nutrition finds that there is no interaction between lutein and DHA (fish oil) supplementations for macular pigment optical density. Therefore, a person taking lutein and fish oil supplements concurrently can expect to obtain the same benefits from each as a person taking them alone.

Forty-nine women age 60-80 years were randomly assigned to placebo, DHA, lutein, or lutein plus DHA supplement. Serum was analyzed for lutein and DHA at baseline, 2 months, and 4 months. Macular pigment optical density (MPOD) was determined at baseline and 4 months at 0.4, 1.5, 3, and 5 degrees temporal to the center of the macula.

The researchers found no interaction between lutein and DHA supplementations for serum lutein and MPOD. In the lutein group MPOD increased at 3.0 degrees (P < 0.01). In the DHA group, MPOD increased at 0.4 degrees (P < 0.05). In the lutein plus DHA group, MPOD increased at 0.4, 1.5, and 3 degrees (P = 0.06, 0.08, and 0.09, respectively).

The investigators conclude that lutein supplementation increased MPOD more peripherally within the macula whereas DHA resulted in increased macular pigment centrally. Lutein and DHA supplementation may aid in prevention of AMD.