Risks and Warnings for Climara (estradiol patch)

If you're taking Climara (estradiol patch) and have your uterus, you might have a higher risk of having endometrial cancer. Vaginal bleeding after menopause can be a warning sign, so let your doctor know if you notice any unusual bleeding. Using medicines like Climara (estradiol patch) for more than a year can increase your risk. Talk to your doctor about other medicines you can take with Climara (estradiol patch) to protect yourself from cancer if you are worried.

This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Pharmacist Q&A

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