In brief:
Complicated

Depends on what else is going on, where the nodes are located, what they feel like on exam, how many and how large, whether they are painful or tender. Single large nodes which are hard to the touch and fixed to underlying tissue will be biopsied quickly.

Multiple small, mildly tender nodes will generally be observed. Anything in between is a judgement call by the doctor.

In brief:
Complicated

Depends on what else is going on, where the nodes are located, what they feel like on exam, how many and how large, whether they are painful or tender. Single large nodes which are hard to the touch and fixed to underlying tissue will be biopsied quickly.

Multiple small, mildly tender nodes will generally be observed. Anything in between is a judgement call by the doctor.
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