9160/0 Cellular angiofibroma

Related terms

Definitions

Connective, subcutaneous and other soft tissues

ICD-O-3 topography code:

C49

Cellular angiofibroma (CA) is a rare benign mesenchymal lesion typically arising in the superficial soft tissues of the vulva and in the inguinoscrotal region. In the vulva, tumours usually measure less than 3cm, whereas tumour size in men ranges from 2.5 to 14 cm. Histologically, CA is characterized by spindle-shaped cells, scattered mast cells, fine collagenous fibres and perivascular hyaline fibrosis. The lesions appear as well circumscribed, highly cellular and richly vascularised nodules. Nearly 50% of cases contain fat, generally near the tumour periphery 1