It is sometimes referred to as S-Adenosylmethionine or S-Adenosyl-L-Methionine.

In the United States it is sold as a nutritional supplement
under the marketing name SAM-e (also spelled SAME or SAMe; pronounced "sam ee").
This means it doesn't have to pass the FDA 's tests required of drugs.

Some research[1] <http://www.ahcpr.gov/clinic/epcsums/samesum.htm> (http://www.ahcpr.gov/clinic/epcsums/samesum.htm)
has shown that taking SAM-e on a regular basis can help fight depression
, liver disease , and the pain of osteoarthritis