GRN

LATE, a form of dementia that appears in the oldest-old is often mistaken for Alzheimer's disease, but the brain pathology is very different. The protein TDP-43 appears to play a significant role in the development of LATE. The neurodegenerative disease may progress more gradually than Alzheimer's, but when combined with Alzheimer's disease (a common combination), appears to cause a more rapid decline than either would alone.... Read More...

Researchers have identified two major groups of genes involved in mutations that result in an overproduction of tau. The findings could offer new avenues for treatments to slow the progression of dementia.... Read More...