Parikh-Doering Oxidation

General Characteristics

The Parikh-Doering oxidation uses SO3•Py(a solid reagent that can be handled easily) as the activator of DMSO. This reaction is especially effective for the oxidation of allylic and secondary alcohols. Unlike the Swern reaction, the reaction works at room temperature and is less prone to the methylthiomethyl ether byproduct formation.