Heart-risk patients got no benefit from fish oil

Eating fish is good for your heart but taking fish-oil capsules does not help people at high risk of heart problems who are already taking medicines to prevent them, a large study in Italy found.

Eating fish is good for your heart but taking fish-oil capsules does not help people at high risk of heart problems who are already taking medicines to prevent them, a large study in Italy found.

The work makes clearer who does and does not benefit from taking supplements of omega-3 fatty acids, the good oils found in fish such as salmon, tuna and sardines.

Previous studies have suggested that fish-oil capsules could lower heart risks in people with heart failure or who already have suffered a heart attack. The American Heart Association recommends them only for people who have high levels of fats called triglycerides in their blood, said the group’s president, Dr. Donna Arnett of the University of Alabama at Birmingham.

Fish-oil capsules failed to prevent flare-ups of atrial fibrillation, a common heart-rhythm problem, in a large study in 2010.

The new study was led by the Mario Negri Institute for Pharmacological Research in Milan. It tested 1 gram a day of fish oil versus dummy capsules in 12,513 people throughout Italy. They had not suffered a heart attack but were at high risk of having one because of conditions such as diabetes, high cholesterol and smoking. Most already were taking cholesterol-lowering statins, aspirin and other medicines to lower their chances of heart problems.

Researchers planned to compare the rate of death, heart attacks and strokes in the two groups, but these were less frequent than anticipated. So they started measuring how long it was before people in either group suffered one of these fates or was hospitalized for heart-related reasons. After five years, the rate was the same — about 12 percent of each group.