Protein Summary

The protein structure reveals a 7-bladed propeller in which each blade is comprised of ~40 residues. This is a secreted protein. The structure is similar to that of WD40/YVTN repeat-like domains, which usually have distinct sequences.

This protein is also similar in structure to TolB (~10-12% seq id to PDB ids 1c5k and 2ojh), which is involved in translocation.

Proteins with WD repeats are involved in a wide variety of functions including enzyme function and scaffolding for forming protein-protein complexes and have been reviewed in several papers (PMID: 10322433, PMID: 8090199, PMID: 21468892).