Dosage and Administration: Shake
well before use. For dogs weighing less than 30 lbs. instill 4 drops of
POSATEX Otic Suspension once daily into the ear canal. For dogs
weighing 30 lbs. or more, instill 8 drops once daily into the ear canal.
Therapy should continue for 7 consecutive days.

Contraindications: POSATEX Otic
Suspension is contraindicated in dogs with known or suspected
hypersensitivity to quinolones, mometasone furoate monohydrate, or
posaconazole. Do not use in dogs with known tympanic perforation (see PRECAUTIONS).

WARNINGS:

Human Warnings: Not for use in humans. Keep out of reach of children.

Animal Warnings: Do not administer
orally. Immediately discontinue use of POSATEX Otic Suspension if
hearing loss is observed during treatment (see ADVERSE REACTIONS).

Precautions: The use of POSATEX
Otic Suspension in dogs with perforated tympanic membranes has not been
evaluated. The integrity of the tympanic membranes should be confirmed
before administering this product.

Avoid prolonged or repeated use of POSATEX Otic
Suspension. Long-term use of topical otic corticosteroids has been
associated with adrenocortical suppression and iatrogenic
hyperadrenocorticism in dogs (see ANIMAL SAFETY).

The safe use of POSATEX Otic Suspension in dogs used
for breeding purposes, during pregnancy or in lactating bitches, has not
been evaluated. The systemic administration of quinolones has been
shown to produce cartilage erosions of weight bearing joints and other
signs of arthropathy in immature animals of various species.

Adverse Reactions: In the field
study, 143 dogs were treated with POSATEX Otic Suspension. Of those, 1
dog with bilateral otitis externa developed hearing loss. POSATEX Otic
Suspension treatment was discontinued and the condition resolved after
one week.

Federal law restricts this drug to use by or on the order of a licensed veterinarian

Federal law prohibits the extra-label use of this drug in food-producing animals.