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Disable SMTP and allow it only for few domains.

Hello all,
I have searched through the forums but still in need of some clarification for this subject:
how may I block the use of SMTP (by mobile and desktop mail clients) for all users except few domains?

I mean I have to allow only few domains to use zimbra auth smtp and leave others to own SMTP services...

As an alternative I would like to simply change SMTP port from 25/465/587 to some other value.