Incurin®

Product class

Incurin®

Incurin is a short acting oestrogen for the treatment of hormone-dependent urinary incontinence.

A short acting oestrogen for the treatment of hormone-dependent urinary incontinence.

Active Ingredients
Contains 1mg/tablet oestriol.

Indications
For the treatment of hormone-responsive urinary incontinence due to sphincter mechanism incompetence in female dogs.

Dosage
Incurin is intended for once daily oral administration. There is no relationship between the size of the dog and the dose required, so a fixed mg/kg dose rate is not feasible.
Effectiveness is defined as no signs of incontinence for 7 consecutive days. An improvement will usually be noticed within a few days. However, adjustment of the initial dose will often be necessary, so at least 7 days should be allowed before judging the full effect of a certain dose rate.

The following dosing schedule is advised:
Initial dose: 1 tablet (1mg) per day for 7-14 days.
(a) If treatment with 1mg daily is effective, try to reduce the dose to the minimum possible with 7 days treatment as follows:
½ tablet/day, then
½ tablet on alternate days
If treatment is ineffective at the lower doses, titrate back to the next lowest dose.
(b) If treatment with 1mg daily is ineffective, increase the dose to 2mg daily for 7 days. (Maximum dose should not exceed 2mg/day). If effective, try reducing dose to 2mg on alternate days. However, if treatment with 2mg/day is ineffective, reassess case to confirm diagnosis, then consider supplementary therapy.