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Publications61

Health and human development: understandings from life-course research

Clyde HertzmanDepartment of Health Care and Epidemiology, University of British Columbia, Vancouver, CanadaDev Neuropsychol 24:719-44. 2003

..Evidence demonstrating these relationships suggests that, without a consideration of early life as well as adult life experience, policies designed to improve health status tend to overlook root causes...

Childhood and adulthood psychological ill health as predictors of midlife affective and anxiety disorders: the 1958 British Birth Cohort

..The contribution of body mass index (BMI) at different life stages to adult blood pressure (BP) is not well known. We investigated whether changes in BMI across childhood and adulthood, and birthweight, influence BP in mid-adulthood...

Social gradients in binge drinking and abstaining: trends in a cohort of British adults

..Genetics and environmental conditions early in life are known to influence height. However, evidence is restricted to studies conducted at a specific age, and thus the effect on the entire growth trajectory has been neglected...

An intergenerational study of birthweight: investigating the birth order effect

..small size at birth has been associated with increased risk of type 2 diabetes. Our aim was to evaluate how risk of diabetes associated with low birth weight is affected by accumulation of body mass from childhood to adulthood...

Physical (in)activity over 20 y in adulthood: associations with adult lipid levels in the 1958 British birth cohort

..To investigate associations between physical (in)activity at different life-stages and lipids in mid-adulthood, examining the role of potential confounding and mediating factors, such as adiposity...

Sex differences in the associations between birthweight and lipid levels in middle-age: findings from the 1958 British birth cohort

25-Hydroxyvitamin D and pre-clinical alterations in inflammatory and hemostatic markers: a cross sectional analysis in the 1958 British Birth Cohort

Elina HyppÃ¶nenMedical Research Council Centre for Epidemiology of Child Health and Centre for Paediatric Epidemiology and Biostatistics, University College London Institute of Child Health, London, UKPLoS ONE 5:e10801. 2010

..Our aim was to investigate the association between 25-hydroxyvitamin D [25(OH)D, a measure for vitamin D status] concentrations with pre-clinical variations in markers of inflammation and hemostasis...

25-hydroxyvitamin D, IGF-1, and metabolic syndrome at 45 years of age: a cross-sectional study in the 1958 British Birth Cohort

..We sought to establish whether associations between childhood cognition and risk factors for cardiovascular disease in adulthood are explained by common causes, or adult social position or health behavior...

Leah LiCentre for Paediatric Epidemiology and Biostatistics Medical Research Council Centre of Epidemiology for Child Health, Institute of Child Health, University College London, 30 Guilford Street, London WC1N1EH, United KingdomAm J Epidemiol 168:1008-15. 2008

..1% vs. 10.8% in males and 23.7% vs. 14.8% in females). Changes in height and adiposity over a relatively short period of 12 years suggest the likelihood of opposing trends of influences on later disease risk in these populations...

Social differences in insulin-like growth factor-1: findings from a British birth cohort

..Our aim is to examine whether there are social differences in IGF-1 in a cohort of participants between 44 and 45 years of age...

Effects of socioeconomic position on inflammatory and hemostatic markers: a life-course analysis in the 1958 British birth cohort

Faiza TabassumDepartment of Epidemiology and Public Health, University College London, London, United KingdomAm J Epidemiol 167:1332-41. 2008

..Risk exposure related to SEP accumulates across the life course and contributes to raised levels of fibrinogen and C-reactive protein, while childhood SEP influences hemostatic markers more than does adult SEP...

Socioeconomic variation in attitudes to eating and weight in female adolescents

..We also assessed whether activity level in adulthood was influenced by activity or television viewing in adolescence or early adulthood and to examine change in diet quality and whether any change was related to change in activity level...

..To examine the combined effect of social class and weight at birth on cognitive trajectories during school age and the associations between birth weight and educational outcomes through to 33 years...

An intergenerational and lifecourse study of health and mortality risk in parents of the 1958 birth cohort: (I) methods and tracing

..In conclusion, we have identified the first type 2 diabetes-susceptibility allele to be reproducibly associated with birth weight. Common gene variants can substantially influence normal birth-weight variation...

Intergenerational obesity involves both the father and the mother

Tim J ColeAm J Clin Nutr 87:1535-6; author reply 1536-7. 2008

Health selection: the role of inter- and intra-generational mobility on social inequalities in health

..However, it is unknown whether this association persists into adulthood. The aim of the current study was to examine, prospectively, whether children with common symptoms experience an increased risk of chronic widespread pain as adults...