Dr.Russo is the medical research director at Phytecs, a biotechnology company with a research focus on the endocannabinoid system. Which explains his focus on the homeostasis created by Cannabinoids.
Their aim is to target the endocannabinoid system directly to target any existing deficiencies within the body and subsequent diseases. They are also looking for non-drug herbal approaches.

Homeostasis

If you want to make yourself familiar with the benefits of cannabinoids (produces NO INTOXICATION, anti-anxiety, anti-psychotic, anti-inflammatory etc.) check out this post.

So first things first, in case you are not familiar with what the endocannabinoid system (ECS) is, here we go:

Cannabinoids = from plants

Endocannabinoids = produced by mammals in their bodies

The ECS It is the body’s own cannabinoid system. Meaning, every mammal has their own receptor system for endocannabinoids and cannabinoids within their bodies as well as creates endocannabinoids within their body. Cannabinoids from plants can bind to those receptors within our bodies. Cannabinoids find receptors in the nervous and immune system.

-There are more receptors in our human brain for cannabinoids than for all other neurotransmitters together.-

So Dr. Russo states that cannabidiol is an endocannabinoid modulator and therefore a homeostatic regulator. This is the reason cannabinoids work for so many diseases which affect different parts of our bodies.

Homeostasis = state of balance and health

Bi-directional effect of CBD = CBD acts as buffer, balances either excess or deficiency in system

What he means by that is that the bi-directional effect of CBD, which always works to create a balance no matter if there is currently a deficiency or an excess, always works toward creating a homeostasis (balance and health).

CBD regulates neurotransmitter functions, it simply does so as a consequence of the imbalance.
CBD needs to be seen as a universal tool, it is not able to only fix one certain issue within our body but every issue that has arisen from an imbalance.

CBD is a regulator for any given issue within the body. Not just a specific one, which makes it incredibly versatile.

CBD can be seen as a tool within the body that does not target one specific ailment within the system but rather aims to act as a buffer tool and balance out any imbalance which creates problems in our bodies.

2. Clinical Endocannabinoid Deficiency

This discovery has led Dr.Russo to the clinical endocannabinoid deficiency theory.

He has found out that diseases such as migraine, irritable bowel syndrome (IBS), and fibromyalgia all have a characteristics in common: they all have disproportionate levels of pain although tissues look ok. Moreover, these diseases tend to occur in the same people, someone who already suffers from migranes is more likely to suffer from IBS later in life. And studies show people suffering from those diseases have endocannabinoid deficiencies.

3. Food and Cannabinoid receptors

There are food ingredients which act on cannabinoid receptors, for instance caryophellene. He makes an important point regarding already existing examples of components of common foods which impact the endocannabinoid system.

"I live and work in Hamburg, Germany. As far as Cannabis is concerned I was an avid adversary (with parental experience). My daughters, however, insisted that my opinion must be based on knowledge. They were right. I still am a strong opponent of “street Cannabis”. Hemp is such a wonderful plant. It does not belong in the hands of criminals who mix highly potent and dangerous drugs. But drug free hemp should be legally available for any human and any animal. Who ever renders an opinion on Cannabis without knowledge of its differing THC contents should better be silent. My passion for drug free hemp and my internationally patented inventions regarding hemp juice, beverages and products thereof have earned me the name hemp juice lady. I like that."

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