Category Archives: BRCA2

BRCA are breast cancer genes

When working properly these are tumor supressors. They protect against breast cancer.

But when they are abnormal and genetically inherited – these are called the BRCA1 and BRCA2 genetic mutations.

Both BRCA mutations (1 and 2) increase risk of breast cancer

Normally women have a 12 % lifetime risk of developing breast cancer. Having a BRCA mutation raises the risk to 50-85% with a high likelihood for a recurrence or a second tumor. Risk is the same for BRCA1 or BRCA2

The differences are the risks of associated other cancers.

Both have the increased risk of ovarian and pancreatic cancers

BRCA1 mutations may have additional risk of these cancers

cervical

uterine

pancreatic

colon cancer

BRCA2 mutations may have additional risk of these cancers

pancreatic

stomach

gallbladder

bile duct

melanoma

Future research will discover more differences between BRCA1 and BRCA2.

Meta

Surgical Artistry

Calvin Lee, MD General Surgery
Tammy Wu, MD Plastic Surgery

2336 Sylvan Ave. #C
Modesto, CA 95355

(209) 551-1888

www.SurgeryToday.com

Disclaimer:

Nothing here is specific medical advice. The information here are notes from a General Surgeon's study of Breast Cancer and Breast Diseases. For specific medical advice please see your doctor in person.