He snapped the shot at the Naughty Dog 30th anniversary art exhibit,
which is currently on display at a the Gallery Nucleus in Alhambra,
California. The exhibit premiered on September 27 and runs through
October 12.

It is unclear if the image of Drake you see above represents what he will look like in-game or only through cinematics.

A teaser trailer for the game released in June 2014
gave us a first look at how Naughty Dog had re-designed Drake for the
new game. This image matches up with what we saw before, in that Drake's
hair is now graying, he appears somewhat thinner, and his face is
scruffy and slightly bruised.

Naughty Dog said previously that A Thief's End will tell a "more personal"
story that delves into who Drake is a person. "It's his greatest
adventure yet and will test his physical limits, his resolve, and
ultimately what he's willing to sacrifice to save the ones he loves,"
Naughty Dog said in June about the game. The game also promises to be an "edge-of-your-seat" roller coaster ride.