The 3'UTR of three proneural genes (achaete, lethal of scute,
and atonal) encoding basic Helix-Loop-Helix (bHLH)
transcriptional activators that initiate neurogenesis in
Drosophila contain a conserved 13 nt long element, AAUGGAAGACAAU,
denoted as the proneural box (PB). The central 7 nt of the PB are
exactly complementary to the GY-box (GYB) present in the 3'UTR of
many Notch pathway target genes in Drosophila.
The predicted duplex interaction, generally more extended than
the 7-m......