Jerry Sands, who hit a solo homer in the seventh, had an RBI double in the fifth when Cleveland scored three times.

Ortiz, who returned to the lineup after not playing in three of the previous six games, belted his 37th home run of the season and 503rd of his career through a 20 mph wind blowing in from right field.

Ortiz was 1-for-3 before leaving for a pinch-hitter in the eighth.

Tomlin has overcome two arm operations in the past three seasons to pitch himself into the Indians' plans for 2016. He missed most of 2013 after Tommy John surgery and had shoulder surgery in March.

The Indians (79-80) will finish over .500 for the third straight season if they win the final two games of the series.

The loss drops the Red Sox (78-82) out of a third-place tie in the AL East and means Boston will finish under .500 for the second straight season.

Owens allowed seven runs and 10 hits in 41/3 innings.

Boston center fielder Mookie Betts recorded his 10th assist of the season when he threw out Francisco Lindor at the plate in the first. Betts walked in the eighth and has reached bases in 35 consecutive games.

Trainer's room

Red Sox: Manager Torey Lovullo said C Ryan Hanigan (sore right hand) is considered day-to-day, but he's likely emergency-only for the final series.

Indians: 2B Jason Kipnis, who has been playing with shoulder and neck injuries for several weeks, wasn't in Friday's lineup.

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Red Sox: LHP Craig Breslow will make his second start of the season Saturday and is expected to throw 50-60 pitches. He pitched four shutout innings against Baltimore on Sept. 26.

Indians: RHP Corey Kluber, who hasn't won since Aug. 14, will make his final start of the season.