Previous HGNC Symbols for HPRT1 Gene

Previous GeneCards Identifiers for HPRT1 Gene

Summaries for HPRT1 Gene

Entrez Gene Summary for HPRT1 Gene

The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.[provided by RefSeq, Jun 2009]

UniProtKB/Swiss-Prot for HPRT1 Gene

Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway.

Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway.

No data available for
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery ,
mRNA differential expression in normal tissues and
mRNA Expression by UniProt/SwissProt
for HPRT1 Gene