We continue our choose or lose picks for Week 2 with the running back position. There were several backs that had monster opening week performances, but there were also some that couldn’t live up to the hype. Most running backs are picked in the first two or three rounds of fantasy drafts and there are also some surprises each year.

Choose

Joseph Randle vs. Eagles

The Eagles’ defense allowed 105 rush yards to the Falcons unproven running backs in Week 1, so what kind of damage can Randle do? He showed what he can be capable of against the Giants, but expect him to have an even bigger game against the Eagles. Add to the fact that Tony Romo doesn’t have Dez Bryant (broken foot), and it should be a heavy dose of run game for the Cowboys on Sunday.

Ameer Abdullah vs. Vikings

Abdullah showed just how much of a presence he will be for the Lions–on his first carry of the game versus the Chargers in Week 1. He finished the game with seven carries for 50 yards and a touchdown to go along with four receptions for 44 yards. He should continue to out-touch Bell in the backfield, and should be able to shred the Vikings’ defense that allowed 49ers’Carlos Hyde to rush for 168 yards against them.

Lose

CJ Anderson vs. Chiefs

Anderson is dealing with a toe injury and is heading into Arrowhead Stadium in primetime. That combination is not one that I like, especially after how anemic the Broncos’ offense looked last week. I don’t like any players in this game, but would especially run away from starting Anderson or even Hillman. The score of this one could closely resemble a Rockies/Royals game than an NFL game.

Latavius Murray vs. Ravens

Murray was okay for the Raiders last week against the Bengals, but I don’t think he will have any success against his second consecutive AFC North opponent. And that is saying something, considering the Ravens’ defense is without Terrell Suggs for the rest of the season due to a torn Achilles. If Derek Carr is out of this Week 2 matchup, I hate Murray even more in this game.

On the Bubble

Carlos Hyde vs. Steelers

Hyde had a career night against the Vikings — rushing for 168 yards and two touchdowns — and it could be more of the same against the Steelers. Pittsburgh‘s defense isn’t the same this season and they allowed Patriots’ running back Dion Lewis to combine for 120 total yards. If the 49ers can keep the pressure off of Kaepernick, this could be another big day for Hyde.