If your wired mouse isn’t working, you’re probably out of luck. Those things are generally foolproof and rely on deep system tools like HID configurations to function. If that doesn’t work, it’s probably an issue with the hardware. Wireless mice, including Logitech mice and the Magic Mouse, are far more likely to suddenly disconnect. If your wireless mouse isn’t working in macOS, try these options listed below.Mouse Not Working in macOS? Use these Fixes

applications like SteerMouse can assign extra buttons to keystrokes and take the place of software that’s not Mac-compatible.