Pablo Machin makes wholesale changes to his side from Wednesday’s draw at Leganes, with just Gorka Iraizoz, Pablo Maffeo, Juanpe and Pere Pons keeping their place in the XI.
Bernardo Espinosa, Jonas Ramalho, Aday Benitez, Aleix Garcia, Portu, Douglas Luiz and Michael Olunga are brought into the side for the derby.