Results: We found a linear correlation between mPAP and the SUV of LP, RV, and PA in all patients (r=0.286, p<0.01; r=0.389, p<0.0001; r=0.499, p<0.0001, respectively). There was a negative correlation between of SUV in LP and TLC for patients with COPD, fibrosis and both diseases (r =-0.374, p=0.002; r=-0.532, p=0.0014; r=-0.739, p<0.0001, respectively). No correlation between pulmonary or myocardial FDG uptake and NT-Pro BNP, FVC or 6MWD was found. Patients with mPAP≥25 mmHg expressed a higher SUV of LP, RV, and PA (0.22 vs. 0.29, p=0.013; 0.75 vs. 1.03, p<0.01; 1.07 vs. 1.19, p<0.01, respectively) compared to patients with mPAP<25 mmHg.

Conclusion: We found that pulmonary and myocardial glucose uptake correlates positively with severity of pulmonary hypertension in patients with end-stage pulmonary disease.