The authors present a case of acrodermatitis enteropathica persisting into adult life. To our knowledge this is the oldest, and only the fourth, reported case persisting in an adult in the medical literature The three adult cases previously reported are discussed. Other significant features of our case are:

Absence of gastrointestinal manifestations;

Failure to culture Candida albicans from skin lesions;

Dramatic response to diiodohydroxyquin (Diodoquin);

Prompt exacerbation of her disease following the administration of cow's milk and equally prompt improvement following the readministration of diiodohydroxyquin.