Our Solution

Hepatic fibrosis is known to increase the stiffness of liver tissue. Resoundant’s MRE technology works with existing MRI scanners to noninvasively measure liver tissue stiffness.

The image on the left shows a typical MRI scan. Now see how our technology reveals more information…

Typical MRI Scan

The scan begins

MRE uses low-frequency mechanical waves during an MRI scan to noninvasively assess the elastic properties of the patient’s soft tissue. A scan takes only 15 seconds.

Mechanical waves in liver during MRE

Our technology at work

When combined with a capable MRI scanner, Resoundant’s proprietary technology can assess soft tissue stiffness and highlight the results in an elastrogram with extremely high degrees of accuracy, consistency and specificity. The technology is available as an upgrade to MRI scanners from GE Healthcare, Siemens and Philips.

Additionally, MRE is not impacted by obesity (high BMI) or the presence of ascites as is the case with ultrasound elastography. Also, the presence of steatosis does not affect liver stiffness with MRE. In several studies MRE demonstrated the ability to identify steatohepatitis before the onset of fibrosis—an important indicator for treatment.2

A Patient’s Perspective — What MRE Feels Like

Mayo Clinic patient K. Anderson describes herself as "a 43-year-old fairly healthy mother of two." She recently volunteered to undergo an MRE exam. "Part of me just wanted to know how exactly someone could vibrate my liver ...the other part of me wanted to know why my liver enzymes are always a little high, something my family physician assures me is nothing to be concerned about."

"On my day off, I went to the lab to experience MRE. It is an experience like no other, and I do mean that in a good way. No needles, no poking and prodding, just a small circular device (much like the surface of a drum) that was strapped around my abdomen before I was moved into the MRI machine. Once in the machine, I was asked to inhale, exhale and then hold my breath. The 'drum' literally vibrated in different drum beats which then helped the physician see a better scan of my liver. It was pretty amazing.

MRE and what it does, makes me think of a marshmallow. Just like a marshmallow fresh out of the bag, a soft liver is good. As a marshmallow gets stale, the surface hardens. I was happy to learn that my liver is soft and healthy -- and to find that out without experiencing any pain."

When compared to DWI and morphologic MR, MRE is shown to have higher sensitivity and specificity than either conventional MR technique.

No needles, no poking and prodding, just a small circular device (much like the surface of a drum) that was strapped around my abdomen before I was moved into the MRI machine.K. Anderson, patient

About Resoundant

Resoundant, Inc is a medical technology company dedicated to improving patient care and diagnosis accuracy by making Magnetic Resonance Elastography (MRE) available around the world. We are based in Rochester, MN and were founded by Mayo Foundation for Medical Education & Research, Mayo Clinic physicians and researchers.

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