Thank you Ed.
We believe this study marks an important first step in the use of nanoparticle technology for the treatment of a variety of testicular disorders. We were especially encouraged by the ability of these nanoparticles to target Sertoli cells and to cross the blood-testis-barrier, which may have major implications for targeting in an in vivo model. We look forward to sharing our further work exploring nanoparticle targeted to the testis in an animal model. Thank you again for your interest!

Intriguing study out of the Cleveland Clinic. We have long sought to find a way to deliver medical treatments to the testicle but have been thwarted by the blood brain barrier. This study demonstrates the feasibility of utilizing nano particles for the delivery of antioxidants to the sertoli cells to protect them from oxidative stress. My hope is that this will result in future studies for directing hormonal or chemotherapeutic agents to the testicles for treatment of infertility or malignancy respectively. Well done.

New Discussion Features!

NEW! Open access free discussion forums on EVERY article in Fertility and Sterility! Just go to the issue and click on article title. You will be able to submit comments questions or share your thoughts on the paper-- Speak your mind!