Leflunomide tablets

What is this medicine?

LEFLUNOMIDE (le FLOO na mide) is for rheumatoid arthritis.

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

breathing problems

cough

increased blood pressure

low blood counts - this medicine may decrease the number of white blood cells and platelets. You may be at increased risk for infections and bleeding.

pain, tingling, numbness in the hands or feet

redness, blistering, peeing or loosening of the skin, including inside the mouth

an unusual or allergic reaction to leflunomide, teriflunomide, other medicines, food, dyes, or preservatives

pregnant or trying to get pregnant

breast-feeding

What should I watch for while using this medicine?

Visit your healthcare professional for regular checks on your progress. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. You may need blood work done while you are taking this medicine.

This medicine may stay in your body for up to 2 years after your last dose. Tell your doctor about any unusual side effects or symptoms. A medicine can be given to help lower your blood levels of this medicine more quickly.

Women must use effective birth control with this medicine. There is a potential for serious side effects to an unborn child. Do not become pregnant while taking this medicine. Inform your doctor if you wish to become pregnant. This medicine remains in your blood after you stop taking it. You must continue using effective birth control until the blood levels have been checked and they are low enough. A medicine can be given to help lower your blood levels of this medicine more quickly. Immediately talk to your doctor if you think you may be pregnant. You may need a pregnancy test. Talk to your health care professional or pharmacist for more information.

You should not receive certain vaccines during your treatment and for a certain time after your treatment with this medication ends. Talk to your health care professional for more information.