Fig. 5

Effects of TRIM3 silencing on the cell cycle of Huh7 and Hep3B cells. The cells were collected for cell cycle distribution analysis with flow cytometry after they were transfected with siTRIM3 or siNC for 48 h. The percentages of cells in the G0/G1 phase were significantly decreased in Huh7 (a) and Hep3B (b) cells transfected with siTRIM3. P values were calculated using Student’s t test. *P < 0.05, **P < 0.01, and ***P < 0.001, versus cells transfected with siNC