The strongest correlations were observed in the superior-superotemporal sector in severe glaucoma eyes: r=0.94 and r=0.90 for the mfPOP LumBal and Lum+Col protocols respectively (both n=16, p<0.05). Correlations across all test-points in both SAP and mfPOP were strongest in eyes with severe glaucoma (SAP MD<-12dB): SAP r=0.56, LumBal r=0.55, Lum+Col r=0.52, Lum+ColBal r=0.41 (all n=192, p<0.05). No significant correlation was observed in normal subjects for mfPOP or SAP. For all patient eyes taken together SAP correlations were higher than mfPOP, however scatterplots of mfPOP/RNFL deviations were quite linear while SAP data saturated.

Conclusions

For both methods the largest correlations with RNFL thickness corresponded to the inferior nasal field of more severely damaged eyes. Head to head comparison of mfPOP and SAP showed similar structure/function relationships.