PATIENT INFORMATION

Read the Patient Information
leaflet that comes with Amturnide before you start taking it and each time you
get a refill. There may be new information. This leaflet does not take the
place of talking with your doctor about your medical condition and treatment.
If you have any questions about Amturnide, ask your doctor or pharmacist.

What is the most important
information I should know about Amturnide?

Amturnide can cause harm or
death to an unborn baby. Talk to your doctor about other ways to lower your blood pressure if you plan to become pregnant. If you get pregnant while taking
Amturnide, tell your doctor right away.

are pregnant or planning to become
pregnant. See “What is the most important information I should know about
Amturnide?”

are breast-feeding. It is not
known if Amturnide passes into your breast milk and if it can harm your baby.
You and your doctor should decide if you will take Amturnide or breastfeed. You
should not do both.

Tell your doctor about all the
medicines you take including prescription
and nonprescription medicines, vitamins and herbal supplements. Amturnide and
certain other medicines may affect each other and cause side effects.

lithium, a medicine used to treat
some types of depression. You should not take Amturnide if you are taking
lithium.

nonsteroidal anti-inflammatory
(NSAIDs) medicines. Ask your doctor if you are not sure if you are taking one
of these medicines.

sleeping pills and anti-seizure
medicines called barbiturates

narcotic pain medicines.

Ask your doctor if you are not
sure whether you are taking one of the medicines listed above.

Know the medicines you take. Keep
a list of them to show your doctor or pharmacist when you get a new medicine.
Your doctor or pharmacist will know what medicines are safe to take together.

How should I take Amturnide?

Take Amturnide exactly as
prescribed by your doctor. It is important to take Amturnide every day to
control your blood pressure.

Take Amturnide one time a day, at
about the same time each day.

Take Amturnide the same way every
day, either with or without a meal.

Your doctor may change your dose
of Amturnide if needed. Do not change the amount of Amturnide you take without
talking to your doctor.

If you miss a dose of Amturnide,
take it as soon as you remember. If it is close to your next dose, do not take
the missed dose. Just take the next dose at your regular time.

If you take too much Amturnide,
call your doctor or a Poison Control Center, or go to the nearest hospital
emergency room.

What should I avoid while
taking Amturnide?

Drinking alcohol. Drinking alcohol during treatment with Amturnide can cause
you to have low blood pressure. See “What are the possible side effects of
Amturnide?”

What are the possible side
effects of Amturnide?

Amturnide may cause serious side
effects, including:

Harm to an unborn baby causing
injury or death. See “What is the most important information I should know
about Amturnide?”

Angioedema. Aliskiren, one of the medicines in Amturnide, can cause
swelling of your face, lips, tongue, throat, arms and legs, or the whole body.
Get medical help right away and tell your doctor if you get any one or more of
these symptoms. Serious allergic reactions can happen at any time while you are
taking Amturnide.

Low blood pressure
(hypotension). Your blood pressure may get
too low if you also take water pills, are on a low-salt diet, get dialysis
treatments, have heart problems, or get sick with vomiting or diarrhea.
Drinking alcohol and taking certain medicines (barbiturates or narcotics) can
cause low blood pressure to get worse. Lie down if you feel faint or dizzy, and
call your doctor right away.

Worsening chest pain or heart
attack. When you first start taking
Amturnide or increase your dose, you may have a heart attack or your angina may
get worse. If that happens, call your doctor right away or go directly to the
nearest hospital emergency room.

Allergic reactions. Hydrochlorothiazide, one of the medicines in Amturnide can
cause allergic reactions.

Worsening of lupus. One of the medicines in Amturnide may cause your lupus to
become active or get worse. Tell your doctor if your lupus gets worse or
becomes active while taking Amturnide.

Eye problems. One of the medicines in Amturnide can cause eye problems
that may lead to vision loss. Symptoms of eye problems can happen within hours
to weeks of starting Amturnide. Tell your doctor right away if you have:

Tell your doctor if you have any
side effect that bothers you or that does not go away. These are not all of the
possible side effects of Amturnide. For more information ask your doctor or pharmacist.

Call your doctor for medical
advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I store Amturnide?

Store Amturnide tablets at room
temperature between 59°F to 86°F (15°C to 30°C).

Keep Amturnide in the original
container.

Protect Amturnide from heat and
moisture.

Keep Amturnide and all
medicines out of the reach of children.

General information about
Amturnide

Medicines are sometimes prescribed
for conditions not listed in the patient information leaflet. Do not take
Amturnide for a condition for which it was not prescribed. Do not give
Amturnide to other people, even if they have the same condition or symptoms you
have. It may harm them.

This leaflet summarizes the most
important information about Amturnide. If you have questions about Amturnide,
talk with your doctor. You can ask your doctor or pharmacist for information that
is written for healthcare professionals.

For more information about
Amturnide, visit www.Amturnide.com, or call 1-888-NOW-NOVA (1-888-669-6682).

Blood pressure is the force of
blood in your blood vessels when your heart beats and when your heart rests.
You have high blood pressure when the force is too much.

High blood pressure makes the
heart work harder to pump blood through the body and causes damage to blood
vessels. Amturnide can help your blood vessels relax so your blood pressure is lower.
Medicines that lower your blood pressure may lower your chance of having a
stroke or heart attack.

Last reviewed on RxList: 2/15/2012
This monograph has been modified to include the generic and brand name in many instances.