BAK1 Antibody

Bcl-2 homologous antagonist/killer, the product of gene BAK1, belongs to the BCL2 protein family. This protein localizes to mitochondria, and functions to induce apoptosis. BAK1 interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress [taken from NCBI Entrez Gene (Gene ID: 578)].