Methods :
We identified 6 patients with anti-VEGF-resistant AMD, due to VMT or ERMs, amongst 588 AMD patients (821 eyes) referred to Okayama University Hospital between February 2012 and May 2014. These patients underwent vitrectomy, which released the VMT (4 cases) or removed the ERM (2 cases), and ILM peeling. The regime used for intravitreal injections of anti-VEGF reagents after surgery was based on the severity of exudative changes in each patient. Preoperative and postoperative best-corrected visual acuities (BCVAs) and central retinal thicknesses (CRT) were compared.