Normal Mitochondrion in a HeLa Cell

Normal mitochondria contain and inner
membrane with two topologically distinct components. The inner boundary
membrane (rendered in white/gray) lies closely apposed to the outer membrane
(rendered in translucent blue) and is connected to the lamellar cristae
(rendered in various colors) through circular crista junctions of relatively
uniform size. Most of the cytochrome c in
mitochondria is found in the intracristal compartments which communicate
with the intermembrane space between the outer membrane and the inner
boundary membrane via the crista junctions.