Step-wise group screening strategies for isolating defective items

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Abstract

Abstract. In this paper, we consider the application of stepwise
group screening procedure to blood screening in
populations with low human immunodeficiency virus (HIV)
prevalence rate. Expressions for the saving rate based on the
expected number of runs (tests) and on an appropriate cost
function considering both the cost of testing and the cost of
pooling operations shall be derived. We shall also derive a
stopping criteria based on the added cost associated with the
operation of pooling. The effect of wrongly specifying the
population infection rate shall also be considered.