Welcome to the third issue of the NEMO newsletter. A lot has changed since the last issue of the newsletter and we wish to thank you all for the work involved in these changes. Since the last PGB meeting in Amsterdam in September 2012 a decision was made for an early termination of the NEMO-1 study, this was not an easy decision to come to but we all agreed that it was the right decision to make. We look forward to NEMO-2 and hope that the experience gained during NEMO-1 will make this a much easier process.

On a sadder note we say good bye to Havinder Hara our clinical trial coordinator, who is moving to a new position. We wish to thank Havinder for all the hard work she put into NEMO-1 and wish her the best of luck for the future.

The Amsterdam Project Governing Board meeting took place on the 24th and 25th of September 2012 and was well attended by participants. A variety of issues were addressed: A review of the data for the patients enrolled so far was analysed and discussed and case studies from two recruiting centres in Cork and Rotterdam were presented.

The NEMO PCC Meeting on the 25th and 26th of April will be held in Hotel Bloom! Rue Royale 250, 1210 Brussels – Belgium | T: +32 (0)2 220 66 11 Just 20 meters away from a Metro station, trams and buses at “Botanique” station on Metro line 2 or 6. Nearest rail connection is at Gare du Nord/North Station (500 meters). http://www.hotelbloom.com/hotel/default-en.htmlPlease find more directions and information below....

The NEMO trial is a pan European Multicentre clinical trial conducted across 6 Member States. The trial received its first “green Light” to start recruitment in August 2011 and the first participant was enrolled in October 2011. Since the project commenced the NEMO core trial office team have met on a regular basis to discuss study related issues and offer support to the clinical trial site . The NEMO core trial office members are a unique partnership of UCC, GOSH, O4CP and UCL. This partnership spans four languages, three countries and two time zones making for some interesting meetings.