STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

nhaS5

Na(+)/H(+) antiporter; Na(+)/H(+) antiporter (698 aa)

Predicted Functional Partners:

nhaS3

Na/H+ antiporter; Na(+)/H(+) antiporter that transports sodium from the cytoplasm into the thylakoid lumen in exchange for protons. Contributes to sodium homeostasis and tolerance. Has also Li(+)/H(+) antiport activity under K(+)-free conditions, but not under K(+)-rich conditions (461 aa)

0.985

slr0822

Cation-transporting ATPase E1-E2 ATPase (953 aa)

0.972

nhaS2

Na+/H+ exchanger; Required for Na(+) uptake into the cell, especially at low external Na(+) concentrations or low Na(+)/K(+) ratios. May be part of a sodium cycle that permits re-entry of sodium into the cell (540 aa)

0.966

sll0556

Hypothetical protein (631 aa)

0.962

nhaS1

Na+/H+ exchanger; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Might be able to function at relatively high concentrations of Na(+) ions. Has also Li(+)/H(+) antiport activity under K(+)-rich conditions, but it might not have any physiological relevance (527 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

nhaS1

nhaS2

SYNGTS_1349

SYNGTS_1919

Na+/H+ exchanger; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Might be able to function at relatively high concentrations of Na(+) ions. Has also Li(+)/H(+) antiport activity under K(+)-rich conditions, but it might not have any physiological relevance

Na+/H+ exchanger; Required for Na(+) uptake into the cell, especially at low external Na(+) concentrations or low Na(+)/K(+) ratios. May be part of a sodium cycle that permits re-entry of sodium into the cell

0.524

nhaS1

nhaS3

SYNGTS_1349

SYNGTS_2369

Na+/H+ exchanger; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Might be able to function at relatively high concentrations of Na(+) ions. Has also Li(+)/H(+) antiport activity under K(+)-rich conditions, but it might not have any physiological relevance

Na/H+ antiporter; Na(+)/H(+) antiporter that transports sodium from the cytoplasm into the thylakoid lumen in exchange for protons. Contributes to sodium homeostasis and tolerance. Has also Li(+)/H(+) antiport activity under K(+)-free conditions, but not under K(+)-rich conditions

0.892

nhaS1

nhaS5

SYNGTS_1349

SYNGTS_2415

Na+/H+ exchanger; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Might be able to function at relatively high concentrations of Na(+) ions. Has also Li(+)/H(+) antiport activity under K(+)-rich conditions, but it might not have any physiological relevance

Na(+)/H(+) antiporter; Na(+)/H(+) antiporter

0.954

nhaS1

pma1

SYNGTS_1349

SYNGTS_1321

Na+/H+ exchanger; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Might be able to function at relatively high concentrations of Na(+) ions. Has also Li(+)/H(+) antiport activity under K(+)-rich conditions, but it might not have any physiological relevance

Cation-transporting ATPase E1-E2 ATPase; Could mediate calcium influx

0.640

nhaS1

sll0282

SYNGTS_1349

SYNGTS_2715

Na+/H+ exchanger; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Might be able to function at relatively high concentrations of Na(+) ions. Has also Li(+)/H(+) antiport activity under K(+)-rich conditions, but it might not have any physiological relevance

Hypothetical protein

0.521

nhaS1

sll0556

SYNGTS_1349

SYNGTS_2514

Na+/H+ exchanger; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Might be able to function at relatively high concentrations of Na(+) ions. Has also Li(+)/H(+) antiport activity under K(+)-rich conditions, but it might not have any physiological relevance

Hypothetical protein

0.795

nhaS1

sll1864

SYNGTS_1349

SYNGTS_2007

Na+/H+ exchanger; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Might be able to function at relatively high concentrations of Na(+) ions. Has also Li(+)/H(+) antiport activity under K(+)-rich conditions, but it might not have any physiological relevance

Chloride channel protein

0.453

nhaS1

slr0309

SYNGTS_1349

SYNGTS_2714

Na+/H+ exchanger; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Might be able to function at relatively high concentrations of Na(+) ions. Has also Li(+)/H(+) antiport activity under K(+)-rich conditions, but it might not have any physiological relevance

P-methylase

0.603

nhaS1

slr0822

SYNGTS_1349

SYNGTS_1563

Na+/H+ exchanger; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Might be able to function at relatively high concentrations of Na(+) ions. Has also Li(+)/H(+) antiport activity under K(+)-rich conditions, but it might not have any physiological relevance

Cation-transporting ATPase E1-E2 ATPase

0.811

nhaS1

slr1507

SYNGTS_1349

SYNGTS_1438

Na+/H+ exchanger; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Might be able to function at relatively high concentrations of Na(+) ions. Has also Li(+)/H(+) antiport activity under K(+)-rich conditions, but it might not have any physiological relevance

Hypothetical protein

0.752

nhaS2

nhaS1

SYNGTS_1919

SYNGTS_1349

Na+/H+ exchanger; Required for Na(+) uptake into the cell, especially at low external Na(+) concentrations or low Na(+)/K(+) ratios. May be part of a sodium cycle that permits re-entry of sodium into the cell

Na+/H+ exchanger; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Might be able to function at relatively high concentrations of Na(+) ions. Has also Li(+)/H(+) antiport activity under K(+)-rich conditions, but it might not have any physiological relevance

0.524

nhaS2

nhaS3

SYNGTS_1919

SYNGTS_2369

Na+/H+ exchanger; Required for Na(+) uptake into the cell, especially at low external Na(+) concentrations or low Na(+)/K(+) ratios. May be part of a sodium cycle that permits re-entry of sodium into the cell

Na/H+ antiporter; Na(+)/H(+) antiporter that transports sodium from the cytoplasm into the thylakoid lumen in exchange for protons. Contributes to sodium homeostasis and tolerance. Has also Li(+)/H(+) antiport activity under K(+)-free conditions, but not under K(+)-rich conditions

0.932

nhaS2

nhaS5

SYNGTS_1919

SYNGTS_2415

Na+/H+ exchanger; Required for Na(+) uptake into the cell, especially at low external Na(+) concentrations or low Na(+)/K(+) ratios. May be part of a sodium cycle that permits re-entry of sodium into the cell

Na(+)/H(+) antiporter; Na(+)/H(+) antiporter

0.966

nhaS2

pma1

SYNGTS_1919

SYNGTS_1321

Na+/H+ exchanger; Required for Na(+) uptake into the cell, especially at low external Na(+) concentrations or low Na(+)/K(+) ratios. May be part of a sodium cycle that permits re-entry of sodium into the cell

Cation-transporting ATPase E1-E2 ATPase; Could mediate calcium influx

0.811

nhaS2

sll0282

SYNGTS_1919

SYNGTS_2715

Na+/H+ exchanger; Required for Na(+) uptake into the cell, especially at low external Na(+) concentrations or low Na(+)/K(+) ratios. May be part of a sodium cycle that permits re-entry of sodium into the cell

Hypothetical protein

0.750

nhaS2

sll0556

SYNGTS_1919

SYNGTS_2514

Na+/H+ exchanger; Required for Na(+) uptake into the cell, especially at low external Na(+) concentrations or low Na(+)/K(+) ratios. May be part of a sodium cycle that permits re-entry of sodium into the cell

Hypothetical protein

0.926

nhaS2

sll1864

SYNGTS_1919

SYNGTS_2007

Na+/H+ exchanger; Required for Na(+) uptake into the cell, especially at low external Na(+) concentrations or low Na(+)/K(+) ratios. May be part of a sodium cycle that permits re-entry of sodium into the cell

Chloride channel protein

0.414

nhaS2

slr0309

SYNGTS_1919

SYNGTS_2714

Na+/H+ exchanger; Required for Na(+) uptake into the cell, especially at low external Na(+) concentrations or low Na(+)/K(+) ratios. May be part of a sodium cycle that permits re-entry of sodium into the cell

P-methylase

0.806

nhaS2

slr0822

SYNGTS_1919

SYNGTS_1563

Na+/H+ exchanger; Required for Na(+) uptake into the cell, especially at low external Na(+) concentrations or low Na(+)/K(+) ratios. May be part of a sodium cycle that permits re-entry of sodium into the cell

Cation-transporting ATPase E1-E2 ATPase

0.885

nhaS2

slr1507

SYNGTS_1919

SYNGTS_1438

Na+/H+ exchanger; Required for Na(+) uptake into the cell, especially at low external Na(+) concentrations or low Na(+)/K(+) ratios. May be part of a sodium cycle that permits re-entry of sodium into the cell

Hypothetical protein

0.849

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)

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Statistical background

For the above enrichment analysis, the following statistical background is assumed: