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Clinical information

Diagnosis:

Deep penetrating naevus.

Comments:

This example shows a conspicuous micronodular architecture.

DEEP PENETRATING NAEVUS

Pigmented papule, usually smaller than 1 cm, wide age range, many body sites

Enlarged naevoid melanocytes with usually lightly (or moderately pigmented cyoplasm and pump, sometimes somewhat pleomorphic and anisochromaticnuclei, at all levels of the lesion (i.e., no so-called 'maturation')

Cells cluster together in small nests and strands

No bulky cell masses (as in some thick melanomas consisting of large cells)

Dermal penetration often centered around a hair follicle, resulting in a wedge shape.

No destruction or gross distorsion of involved skin

Mitotic figures commonly present and may be found at all levels of the lesion, but they are not numerous

Some lymphocytic inflammatory infiltrates may be present; no plasmocellular infiltrates

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