Diabetes mellitus results in chronic hyperglycaemia, leading to defects in carbohydrate, fat and protein metabolism. Diabetes mellitus is also linked with elevated plasma cholesterol and triglyceride levels, which may ...

Three (3) medicinal plants [Aframomum melegueta K. Schum., Xylopia aethiopica (Dunal.) A. Rich. and Capsicum annuum L.] were selected based on their traditional uses in the treatment of diabetes in Africa. Various crude ...

Satellite cells are muscle stem cells that reside in a niche between the basal lamina and
sarcolemma of mature muscle fibers. Upon muscle injury, these cells are activated to
myoblasts that subsequently proliferate, ...

Cancer is a disease characterized by accelerated cell growth, resulting in healthy tissue being destroyed by the processes of invasion and metastasis. Non-viral gene delivery approaches have been extensively studied as a ...

The need for the improvement in protocols for cellular gene delivery has propelled cytofectin based liposomes as suitable non-viral gene carriers. The amenability of cationic liposomes to modification enables research based ...

Gene therapy has become an important strategy to treat several human diseases, including cancer, viral infections and inherited disorders. In response to this growing trend, a number of gene delivery vectors have been ...

ADEKUNLE ADEBOWALE Ph.D. thesis, University of KwaZulu-Natal, 2014
Strychnos L. is the largest genus of the pantropical or subtropical family
Loganiaceae with about 200 species. Their habits range from trees and shrubs ...

Evidence is presented for DNA delivery to cultured HepG2 hepatoma cells via the endocytotic pathway, under the direction of insulin, in a soluble system of transfection leading to
stable gene expression. Serum albumin ...

African horse sickness (AHS) is a viral disease that afflicts all equine species and has a 90%
mortality rate in unvaccinated horses. The disease has a devastating effect on the national
herd of South Africa each year ...

This thesis examined the in vitro and in vivo anti-oxidative and anti-diabetic activities of five African medicinal plants which are traditionally used for the treatment of diabetes mellitus viz; Ziziphus mucronata, Cassia ...