Russell isn’t the only nominee seeking her first win. Empire‘s Taraji P. Henson, Orphan Black‘s Tatiana Maslany (entering the race for the second consecutive year) and House of Cards‘ Robin Wright (scoring her fourth straight nom) have yet to pick up Emmy gold. Claire Danes, meanwhile, is a three-time Emmy champ.

In the end, voters may ultimately choose to award Viola Davis again for her performance in How to Get Away With Murder (although she’d face an uphill battle trying to top last year’s acceptance speech).

What would you do if you had the opportunity to recognize one of the aforementioned leads when the Emmys are handed out on Sept. 18? Take our poll below to vote for your favorite, then hit the comments to defend your pick.

Every day for the next couple of weeks, we’ll launch another “Who Should Win?” Emmy poll, so visit TVLine.com daily to weigh in on who’s most worthy of TV’s most distinguished honor.