An analysis of the genomes and epigenomes of lean and obese mice and humans has turned up a wealth of clues about how genes and the environment conspire to trigger diabetes, Johns Hopkins researchers say. ...

Researchers at Harvard School of Public Health (HSPH) have found a novel mechanism causing type 2 diabetes that could be targeted to prevent or treat the disease. The research highlights a previously unrecognized molecular ...

(Medical Xpress)—New findings about the biological links between obesity and insulin resistance and Type 2 diabetes may also shed light on the connection between obesity and cancer, says a scientist at ...

In mice with diet-induced diabetes—the equivalent of type 2 diabetes in humans—a single injection of the protein FGF1 is enough to restore blood sugar levels to a healthy range for more than two days. ...

Western diets are often rich in advanced glycation end-products (AGEs). Also known as glycotoxins, AGEs are found in processed foods. Weijing Cai of The Icahn School of Medicine at Mount Sinai and his colleagues have found ...

(Medical Xpress)—Chronic treatment with low doses of a drug used to boost organ survival in transplant patients has been found to improve metabolism and heart dysfunction in an animal model, according to ...

(Medical Xpress)—Akkermansia muciniphila is one of the many microbes that live in our intestines. This bacterium, which feeds on the intestine's mucus lining, comprises between 3 and 5 percent of the gut microbes of hea ...

Early life exposure to normal bacteria of the GI tract (gut microbes) protects against autoimmune disease in mice, according to research published on-line in the January 17 edition of Science. The study ...

Striking new evidence suggesting that diet and related factors early in life can boost the risk for breast cancer—totally independent of the body's production of the hormone estrogen—has been uncovered by a team of researchers ...

The injection of a tiny capsule containing heat-generating cells into the abdomens of mice led those animals to burn abdominal fat and initially lose about 20 percent of belly fat after 80 days of treatment.

(Medical Xpress) -- University of Florida researchers teamed with colleagues at City of Hope National Medical Center in Duarte, Calif., to devise a new combination therapy that reverses established Type 1 diabetes in mice.