A lightweight, flexible browser framework to display large population datasets of genetic variation. ExAC browser provides gene- and transcript-centric displays of variation, a critical view for clinical applications. Additionally, it provides a variant display, which includes population frequency and functional annotation data as well as short read support for the called variant. This browser is an open-source, freely available and has already been used extensively by clinical laboratories worldwide.

Funding source(s)

This work was supported by the NIGMS Fellowship (F32GM115208); Australian National Health and Medical Research Council C.J. Martin Fellowship, Australian American Association Sir Keith Murdoch Fellowship; the MDA/AANEM Development Grant and NIGMS (R01 GM104371 and NIDDK U54 DK105566).