Oxytocin may play a role in autism and may be an effective treatment for autism's repetitive and affiliative behaviors&period; Oxytocin treatments also resulted in an increased retention of affective speech in adults with autism&period; Two related studies in adults&comma; in 2003 and 2007&comma; found oxytocin decreased repetitive behaviors and improved interpretation of emotions&period; More recently&comma; intranasal administration of oxytocin was found to increase emotion recognition in children as young as 12 who are diagnosed with autism spectrum disorders&period;

Oxytocin is destroyed in the gastrointestinal tract&comma; so must be administered by injection or as nasal spray&period; It has a half-life of typically about three minutes in the blood&comma; and given intravenously does not enter the brain in significant quantities - it is excluded from the brain by the blood-brain barrier&period; Evidence in rhesus macaques indicates oxytocin by nasal spray does enter the brain&period; Oxytocin nasal sprays have been used to stimulate breastfeeding&comma; but the efficacy of this approach is doubtful&period;

3&period;Product Application&colon;

Oxytocin &lpar;Oxt&rpar; is a mammalian neurohypophysial hormone&period; Produced by the hypothalamus and stored and secreted by the posterior pituitary gland&comma; oxytocin acts primarily as a neuromodulator in the brain&period;Oxytocin plays an important role in the neuroanatomy of intimacy&comma; specifically in sexual reproduction of both sexes&comma; in particular during and after childbirth&semi; its name&comma; meaning "swift childbirth"&comma; comes from Greek&comma; oksys "swift" and &comma; tokos "birth&period;" It is released in large amounts after distension of the cervix and uterus during labor&comma; facilitating birth&comma; maternal bonding&comma; and&comma; after stimulation of the nipples&comma; lactation&period; Both childbirth and milk ejection result from positive feedback mechanisms&period;&period;

Injected oxytocin analogues are used for labor induction and to support labor in case of difficult parturition&period; It has largely replaced as the principal agent to increase uterine tone in acute postpartum hemorrhage&period; Oxytocin is also used in veterinary medicine to facilitate birth and to stimulate milk release&period; The tocolyticagent atosiban &lpar;Tractocile&rpar; acts as an antagonist of oxytocin receptors&semi; this drug is registered in many countries to suppress premature labor between 24 and 33 weeks of gestation&period; It has fewer side effects than drugs previously used for this purpose &lpar;ritodrine&rpar;&period;

4&period;Function&colon;

Oxytocin is indicated by the parenteral route for nonelective of labor for medical reasons and for stimulation or reinforcement of laborin patients with dysfunctional interia parenteral oxytocin is also indicated for management of inevitable&comma; incomplete or missed abortion&comma; as well as to produce uterine contractions during the third stage of labour and to control postpartum bleeding or hemorrhage oxytocin lias been administered parenterally to assess fetal respiratory capabilities in high-risk pregnanciesOxytocin has been intranasally for stimulation of milk jcction when it is impaired

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