In my place of work with several hundred advisors account lockouts are a very frequent occurance, and of course the system administrators must unlock them, not a difficult or time consuming task but certanly one that could be easier.
Late last year I had written a ASP.NET page which enumerated the accounts on a domain and allowed them to be unlocked on the site, so this application simply takes it into the application domain and adds some functionality sugar to the core function.

The application sits in the system tray and checks at the specified interval, listing locked accounts in a drop down. Accounts can be unlocked at once or all together.

There is a hellishly annoying pop up option that displays a bubble alert from the system tray when locked accounts are detected on the domain. It's crude but works, I'll update it here if I update it.