phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially

hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce

inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their

full-length nature has not been determined. (provided by RefSeq, Jul 2008)

GeneCards Summary for PLA2G5 Gene:

PLA2G5 (phospholipase A2, group V) is a protein-coding gene. Diseases associated with PLA2G5 include fleck retina, familial benign, and fundus albipunctatus. GO annotations related to this gene include calcium-dependent phospholipase A2 activity and calcium ion binding. An important paralog of this gene is ENSG00000258417.