After getting off to a slow because of two unlikely fumbles, the New Orleans Saints powered their past the Detroit Lions 45-28 Saturday night in another record-setting performance by the offense in a wild-card playoff game at the Mercedes-Benz Superdome.

The Saints (14-3) will play at the San Francisco 49ers (13-3) next Saturday at 3:30 p.m. in the divisional round of the playoffs. The Saints capped a perfect 9-0 home campaign with the blowout win over the Lions (10-7), who were making their first playoff appearance since 1999.

Saints quarterback Drew Brees, who set the single-season yardage record this season with 5,476, was 33 of 43 for 466 yards and three touchdowns. He received strong support from his running backs who combined for 167 yards on 36 carries.

The Lions put up a good fight for three quarters behind the passing of Matthew Stafford (380 yards, two TDs) and the receiving of Calvin Johnson (12 receptions, 211 yards, two TDs).