Dyfed-Powys Police said three children, aged 13, 12 and 10, escaped the fire.

Emotional tributes have been left at the scene of the tragedy.

(Image: Daily Mirror)

(Image: Daily Mirror)

One heartbreaking note left by a young girl read: "I miss you all. I know you all in school. I will miss my best friend."

Another read: "RIP. Fly high with the angels."

One more tribute left at the scene said: "Such a terrible tragedy, special thoughts to family and friends."

A collection bucket to raise money for the family has also been set up. A note on the container reads: "Collection for Llangammarch Wells Tragedy 'The Children'".

A fundraising page on the JustGiving website has also received donations totalling more than £11,000.

Flowers and cuddly toys are left at the scene of the fire (Image: Ben Birchall/PA)

(Image: Daily Mirror)

A collection bucket has also been set up (Image: WALES NEWS SERVICE)

Police say the start of the fire is "unexplained" (Image: Wales News Service)

Police have said the cause of the devastating blaze remains "unexplained".

Superintendent Jon Cummins, from Dyfed-Powys Police, said: "Based on current information available to us, we are working on the hypothesis that one adult male and five children, aged between 11 and four years old, are unaccounted for and believed to be deceased within the house.

"Due to the severity of damage at the scene we are unable at this stage to identify any of the deceased."

(Image: Mirror)

The house is a burned-out shell (Image: Wales News Service)

(Image: Wales News Service)

He added: "Specialist scientists and fire investigators continue to assess the scene, which is very complex and perilous.

"The 13, 12 and 10-year-old children that managed to escape remain in hospital.

“None are in a life-threatening condition, and they are being supported by specialist officers and family.

“This is a tragic incident, and our deepest sympathies are with the family and all those affected.”