Towing with 22.5's?

I'm thinking about buying a set of these for my dually Duramax but I am just wondering how are the primary lugs going to hold up since they have to use those adapters. Is anyone using these wheels on a DRW Duramax pulling loads at near maximum GCVWR? If so, how many miles do you have doing this? Even though nothing may have broke at first, I was concerned about prolonged metal fatigue on the primary lugs. Thanks for any advice or input.

Your wheel studs are likely not going to cause a problem, but those huge gaudy wheels and tires are hard on balljoints, steering joints, bearings, and basically the rest of the suspension and drivetrain as they are much heavier. If I was pulling on a consistant basis as heavy as you mention, I wouldn't go with those big heavy truck tires and wheels. If I had to have something bigger, I'd go with 19.5's. A lot lighter, not as tall, and looks better too.

Thanks RJF, I was actually leaning towards the 19.5's. I just found a good deal on 6 aluminum 22.5's so I was curious. But now that I add in the extra cost for the tires and those adapters it actually comes out costing more.