With a few exceptions anytime a system has issues when gaming it either comes down to video or audio drivers.

In your case it is the Real Teck High Definition onboard audio driver RtkHDAud.sys. Update these drivers. If this is built by the likes of Dell, etc. go to the website, find your exact system model, and update.

If built by you you will find the drivers at your motherboard's website. Make sure it is for your exact model.