The Resolution of Ibuprofen, 2-(4′-Isobutylphenyl)propionic AcidJames V. McCullaghIn this experiment the over-the-counter pain reliever ibuprofen is resolved using (S)-(-)-a-phenethylamine as the resolving agent. This procedure has several key advantages over previous resolution experiments.McCullagh, James V. J. Chem. Educ.2008, 85, 941.

Chirality / Optical Activity |

Drugs / Pharmaceuticals |

Enantiomers |

Quantitative Analysis |

Separation Science

The Same and Not the Same: Chirality, Topicity, and Memory of ChiralityWolfgang H. Kramer and Axel G. GriesbeckDescribes a simple molecular approach that aids students in learning stereochemical terms, definitions, and concepts, particularly when chemical structures are drawn in two dimensions.Kramer, Wolfgang H.; Griesbeck, Axel G. J. Chem. Educ.2008, 85, 701.