An HDL cholesterol less than 40 mg/dL is low and constitutes a coronary heart disease risk factor. An HDL cholesterol greater than 60 mg/dL is a negative risk factor for coronary heart disease.

Non-HDL cholesterol is a secondary target of therapy in persons with high serum triglycerides (greater than 199 mg/dL). The goal for non-HDL cholesterol in persons with high triglycerides is 30 mg/dL higher than their LDL cholesterol goal.

CHD Risk Factors+1 Age: Men, 45 years and older Women, 55 years and older or premature menopause without estrogen therapy+1 Family history of premature CHD+1 Current smoking+1 Hypertension+1 Diabetes mellitus+1 Low HDLcholesterol: 39 mg/dL or less-1 High HDLcholesterol: 60 mg/dL or greater

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