Yea I think so. I think he will come back after the apocalypse and then youll be able to play as him again. He'll wake up handcuffed and be like what a wild night I had last night. He escapes finds a 24 year old Clementine and then they buy his parents shop they live happily ever after.

I'm actually hoping that if you cut off your arm, had yourself locked to your radiator, and then told Clem to save the bullet, then there's an extra scene in Season 2 where you could travel to the same building, expecting to find a zombified Lee, only to see an open pair of handcuffs.

Reasoning behind that is that while Lee looked pretty fucked up, he also cut off his arm not even 24 hours ago, was suffering from bloodloss, and had been running on adrenaline for quite some time. I don't think we should immediately know he's alive, but a subtle hint that he may be running around still would be nice if you took the precautions.