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Rahim Yar Khan is the last district of Punjab province and is located at the junction of three provinces of Pakistan i.e. Sindh, Punjab and Balochistan. Rahim Yar Khan is named after one of the grandsons of Nawab of Bahawalpur. It is one of the top districts of Pakistan in agriculture production and revenue generation. It is linked by air to the other parts of the country and is situated on the main railway line and National Highway linking Karachi, Lahore and Peshawar & CPEC Motorway.
The Sheikh Zayed Medical College Rahim Yar khan was established in March 2003 as a self-financing medical institute. In 2008, Government of Punjab abolished self-finance seats in medical and dental institutions of the Punjab and converted all these seats into open merit seats. Prof. Dr. Eice Muhammad was its first Principal while Prof. Dr. Zafar Hussain Tanveer is its present Principal.

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The SZMC/H is a tertiary healthcare institution striving hard towards excellence in teaching and training of Health Professionals and has become a role model of medical education and patient care. With the completion of new college building in 2017, the basic sciences departments and administration of the college has been shifted to this new Campus which is located in the east of Sheikh Zayed Hospital.

The complex spreads on area of around 140 acres. The college has vastly experienced and highly committed and dedicated faculty of 162 members including 20 Professors. In a short span of few years, the College has gained a good fame & includes among one of the top medical institutions of the country, grooming and producing skilled and dedicated graduate and post-graduate doctors.
The students / graduates of this college are known as “Zaydians”. The college has number of societies run by the students as co-curricular activities such as Sports society, literary society, Zaydian’s Arts society, Zaydian blood donor society and HUMAINE society. The college publishes a yearly literary magazine “Raigzaar” and a quarterly scientific journal “Journal of SZMC”, recognized by PMDC, containing research articles. The college has number of play grounds for cricket & football while the facility of indoor games is also available. The college cafeteria is also providing good quality hygienic food to the students.
The college has well established department of Medical Education which is being supervised by a team of expert medical educationists who conduct regular workshops for faculty to update their knowledge and equip them with modern medical education skills. The college has two state of the art libraries with internet facility while in the hostels separate reading rooms are available. The college has also newly built hostels for girls and boys with all the living facilities. Accommodation for the faculty has been recently completed and ready to handover.

The college is affiliated with the 1228-bedded Sheikh Zayed Hospital for undergraduate and postgraduate clinical training. This hospital has all the tertiary care health facilities with 25 disciplines recognized by PMDC and CPSP for post graduate training, 2nd tertiary care Institution after KEMU Lahore having maximum number of disciplines accredited by CPSP and affiliated with UHS Lahore for MBBS, MS & MD. The hospital has well established state of the art modern diagnostic facilities; CT, CT Angio, MRI, Mammography, Fluoroscopy, Urodynamics, PCR, Hormonal assay, BERA (Brain stem evoke response audiometry), modern diagnostic ophthalmological equipment. Therapeutic facilities including all types of Microscopic / laparoscopic / Endoscopic procedures, lithotripsy, arthroscopy, joint replacement, re-union of amputated parts, all sort of dental and maxillofacial surgery, all type of ophthalmic surgeries including Vitreo-retina surgery, Oculoplasty and low vision aid clinic, vascular surgery and cardiac surgery and cardiology department with facility of angiography, angioplasty and Coronary artery bypass surgery (CABG). There is also a well-established state of the art Adults, Pediatric & Neonatal ICU and Thalassemia center. Newly built 124 bedded emergency block have all facilities to cope up with all sort of emergencies. The H.H. Sheikh Khalifa Allied Health Sciences School is a part of the college where doctor of Physiotherapy (DPT) and B.Sc.(Honors’) allied health sciences courses are being offered. The School of nursing of Sheikh Zayed Hospital is also showing excellent performance and producing trained staff nurses who play vital role in the delivery of healthcare services to the needy and ailing humanity almost all over the country. The new building for college of nursing has become completed and ready to function in near future.