Description

Reacts with the α5 integrin, a dimer of 135/25 kDa, that associates with β1 integrin (CD29) to form VLA-5, a well-established fibronectin receptor that is expressed on many cell types, including fibroblasts, endothelial cells, epithelial cells, platelets, peripheral T cells, the myeloid cell line U937, K562 and some melanoma cell lines. This clone does not inhibit α5β1/ligand binding.

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.