On your mark, get set, go start a company! The Grand Finale of the 14th Annual Duke Start-Up Challenge is Thursday, April 11. Student teams have previously devised plans for businesses that would recycle fish guts, sell carbonated iced-tea, improve prosthetic arms and more. But only one team will win the $50,000 grand prize.

In research news, Duke Medicine scientists have come up with a new plan for producing an HIV vaccine. The approach, described this week in the Journal Nature, was developed by tracking people's immune responses to the HIV virus in the very earliest days of infection.

Duke fundraising efforts are moving forward. The Duke Forward capital campaign events are bringing the energy and insights of campus to cities around the country.

Mark your calendars. The Full Frame documentary film festival runs April 4 through 7. Former presidential candidate Jon Huntsman talks on campus April 11. And, reunion weekend runs April 12 through 14.