In fluorescent lamps, mercury is used as the primary ion from which light is emitted. Krypton is the buffer gas used in conjunction with the mercury which is used to moderate the momentum of collisions of mercury ions in order to reduce the damage done to the electrodes in the fluorescent lamp. Generally speaking, the longest lasting lamps are those with the heaviest noble gases as buffer gases.

Buffer gas loading techniques have been developed for use in cooling paramagnetic atoms and molecules at ultra-cold temperatures. The buffer gas most commonly used in this sort of application is helium. Buffer gas cooling can be used on just about any molecule, as long as the molecule is capable of surviving multiple collisions with low energy helium atoms, which most molecules are capable of doing. Buffer gas cooling is allowing the molecules of interest to be cooled through elastic collisions with a cold buffer gas inside a chamber (see Figure (a)). If there are enough collisions between the buffer gas and the other molecules of interest before the molecules hit the walls of the chamber and are gone, the buffer gas will sufficiently cool the atoms. Of the two isotopes of helium (3He and 4He), the rarer 3He is sometimes used over 4He as it provides significantly higher vapor pressures and buffer gas density at sub-kelvin temperatures.

Buffer gases are also commonly used in compressors used in power plants for supplying gas to gas turbines. The buffer gas fills the spaces between seals in the compressor. This space is usually about 2 micrometres wide. The gas must be completely dry and free of any contaminants. Contaminants can potentially lodge in the space between the seal and cause metal to metal contact in the compressor, leading to compressor failure (above right). In this case the buffer gas acts in a way much like oil does in an automotive engine’s bearings.