It seems as if it would be impossible to make a movie about your husband cheating on you with Cameron Diaz and Kate Upton without thinking about your husband cheating on you with Cameron Diaz and Kate Upton.

But comic actress Leslie Mann, who is married to comedy writer, director and producer Judd Apatow, insists that she never harbored such a thought … until we brought it up.

Mann, who was directed by Apatow in the films “Knocked Up,” “This Is 40” and “Funny People,” said she trusts her husband, whom she met on the set of her first film, “The Cable Guy,” which he produced. Her movie husband is another matter.

In “The Other Woman,” directed by Nick Cassavetes of “The Notebook,” Mann is the trusting wife of a serial womanizer played by “Game of Thrones” star Nikolaj Coster-Waldau. She learns he is having a torrid affair with Diaz, and after she confronts her husband’s mistress, discovers that he is cheating on both of them with an even younger woman, played by 21-year-old Sports Illustrated cover model Kate Upton. The three plot revenge reminiscent of the movies “Nine to Five” and “The First Wives Club.”

Q.What would upset you more – if your husband had an affair with Cameron Diaz or Kate Upton?

A. Whaaaat?

Q. You heard me.

A. I think that if Judd had an affair, it should be with one of them. I love them both so much. (Laughs) I’d be happy with either one.

Q.You’d be happy?

A. Sure. If he’s going to do it, he should do it with girls I love. (Laughs)

Q. On a more serious note, what are your thoughts about spousal cheating?

A. I’m not sure. Do you mean like Nikolaj’s character in the movie?

Q.No, I’m talking about real life.

A. Who am I to say? I never feel like an authority on subjects like this. Or any subject, for that matter.

Q.Let’s not make it so general. How would you feel about your husband cheating?

A. I’d be really surprised.

Q.Why?

A. Because he always seems super-busy. Oh, wait, maybe he is cheating. (Laughs) He could be cheating on me left and right, and I would have no idea.

Q.Your character in this film also was surprised.

A. Yes, she was very naive. Just like me.

Q.Your roles keep getting bigger and it seems like you’re finally hitting your stride as an actress, particularly now that you’ve gotten away from the clutches of your husband.

A. (Laughs) It was so much fun to be directed by someone else. Nick also directed “The Notebook,” which is one of my favorite movies.

Q.How was it different than being directed by your husband?

A. Nick really pushed me out of my comfort zone. I would do a take and he would go, “More, more, bigger, bigger.”

Q. Was it good to be pushed like that?

A. It was particularly fun with Nick. When we first met, he said he wanted this character to be so hopeful and loving. I thought: “That sounds like the most fun ever.” It made me happy to have that much hope. He was really great for me. It’s a lot more work with Judd.

Q. In what way?

A. He’s always rewriting the scenes, so you have to constantly learn new lines. And he likes to do a lot of takes. In this movie, we stuck to the script and did only five takes. Then we got to go to our trailers and rest between scenes.

Q. You three actresses have been touring together to promote this movie, and it seems like you get along quite well. But you are actresses, so I’m not sure whether it’s just an act.

A. No, we really do get along.

Q. How important is it to get along when you have to play three women who get along?

A. I think it would be really hard if we didn’t get along because we spent a lot of time together, working during the day and partying at night, particularly when we were on location. We had rooms next to each other and we’d hang out and do girly things.

Q. I understand you and Cameron being friendly because you’re closer in age, but I don’t understand how a 21-year-old supermodel fits into this group.

A. She’s five years older than my daughter, and I felt very protective toward her. When she came on, I remembered how I felt on my first movie. I was scared to death, being around Jim Carrey, Ben Stiller and Matthew Broderick (on the set of “The Cable Guy”). I had ideas, but I was so afraid to express them because I didn’t want to look like an idiot. I knew that Kate must have felt the same way, so Cameron and I created a safe space for her to experiment and fail. She was really funny and did a lot of improvisation. But she’s really young.

Q. What’s the set like when your characters are supposed to be bonding? Is it all work or is it fun?

A. There’s work happening, but we got distracted here and there. They would have to tell us to focus. But don’t forget we were working in New York City, the Hamptons and the Bahamas, so it really wasn’t like work. In the Bahamas, we would go skinny-dipping at night in the ocean in front of our hotel. It wasn’t that hard to take.

Q.I have teased you before about Judd holding you back in your career, but you’re adamant that you wouldn’t trade your family life for a bigger career. With a role like this, are you prepared to change that position?

A. My family’s still No. 1, but what’s happening now is that my kids are getting older – Maude is 16 and Iris is 11 – so they have a lot going on in their lives. They still need me all the time, and I still need them all the time, but there’s a little more room for me to do what I want to do.

Q.Why were you suddenly open to travel for this movie and leaving your family behind in Los Angeles?

A. I had never done that before, but Judd was willing to stay home with the girls. It was only a three-week period when they were still in school, so they had to stay home. But Judd was great, and I have to confess that it was so much fun to have my space. I don’t want to sound like a terrible mom, but it was nice to have a break like that. But the kids were like, “We’re fine, Mom. Have fun.” They probably could care less, and I was traumatized that I had to leave them for three weeks.

Q. Now that you’ve whetted your appetite, are you ready to travel more for your work?

A. I’m open to more than I used to be. I enjoyed this experience so much that I’d love to have another one. But I always think that when I’m 65, I don’t want to have any regrets. I don’t want to feel that I took some stupid movie that didn’t mean anything instead of spending more time with my family. Those are my priorities. But maybe if it was a great movie ... (Laughs)

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