A 64-year-old man visited our hospital with a chief complaint of appetite
loss and epigastralgia. Upper GI series and an endoscopic examination revealed type 3
carcinoma on the upper third. Abdominal CT scan showed enlargement of the paraaortic
lymph nodes that had invaded the pancreas. Preoperative diagnosis was cStage Ⅳ
gastric cancer, and we considered a curative operation impossible. Therefore,
chemotherapy with a combination therapy of 5-fluorouracil (5-FU) and low-dose cisplatin
(CDDP) was planned. After 19 days of administration, the patient without vascular risk
factors suddenly exhibited diplopia and left-member weakness. Brain CT showed a low-
density area at the occipital lobe. Though we diagnosed cerebral infarction and treated
with anti-thrombus therapy, he died of multiple cerebral infarction on day 12 of the
treatrnent.