STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Acin_0351

SUN protein (445 aa)

Predicted Functional Partners:

Acin_0355

Ribosome small subunit-dependent GTPase A; May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (295 aa)

Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs (352 aa)

0.902

Acin_0353

Hypothetical protein (243 aa)

0.899

Acin_0350

Hypothetical protein (246 aa)

0.887

rplJ

50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors (177 aa)

0.870

fmt

methionyl-tRNA formyltransferase; Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by- (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (312 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

Acin_0350

Acin_0351

Acin_0350

Acin_0351

Hypothetical protein

SUN protein

0.887

Acin_0350

Acin_0353

Acin_0350

Acin_0353

Hypothetical protein

Hypothetical protein

0.887

Acin_0350

Acin_0354

Acin_0350

Acin_0354

Hypothetical protein

Serine/threonine protein kinase

0.887

Acin_0350

Acin_0355

Acin_0350

Acin_0355

Hypothetical protein

Ribosome small subunit-dependent GTPase A; May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover

0.887

Acin_0350

fmt

Acin_0350

Acin_0349

Hypothetical protein

methionyl-tRNA formyltransferase; Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by- (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP

0.800

Acin_0350

rlmN

Acin_0350

Acin_0352

Hypothetical protein

Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs

0.887

Acin_0350

rpe

Acin_0350

Acin_0356

Hypothetical protein

Ribulose-phosphate 3-epimerase

0.887

Acin_0351

Acin_0350

Acin_0351

Acin_0350

SUN protein

Hypothetical protein

0.887

Acin_0351

Acin_0353

Acin_0351

Acin_0353

SUN protein

Hypothetical protein

0.899

Acin_0351

Acin_0354

Acin_0351

Acin_0354

SUN protein

Serine/threonine protein kinase

0.912

Acin_0351

Acin_0355

Acin_0351

Acin_0355

SUN protein

Ribosome small subunit-dependent GTPase A; May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover

0.922

Acin_0351

Acin_0404

Acin_0351

Acin_0404

SUN protein

Hypothetical protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity

0.911

Acin_0351

fmt

Acin_0351

Acin_0349

SUN protein

methionyl-tRNA formyltransferase; Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by- (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP

0.865

Acin_0351

rlmN

Acin_0351

Acin_0352

SUN protein

Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs

0.902

Acin_0351

rpe

Acin_0351

Acin_0356

SUN protein

Ribulose-phosphate 3-epimerase

0.908

Acin_0351

rplJ

Acin_0351

Acin_2209

SUN protein

50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors

0.870

Acin_0351

rpsA

Acin_0351

Acin_1168

SUN protein

4-hydroxy-3-methylbut-2-enyl diphosphate reductase

0.910

Acin_0353

Acin_0350

Acin_0353

Acin_0350

Hypothetical protein

Hypothetical protein

0.887

Acin_0353

Acin_0351

Acin_0353

Acin_0351

Hypothetical protein

SUN protein

0.899

Acin_0353

Acin_0354

Acin_0353

Acin_0354

Hypothetical protein

Serine/threonine protein kinase

0.999

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Network Stats

Network Stats analysis is still ongoing, please wait ...

Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: