Weitere Proteine zu SATB Homeobox 2 (SATB2) Interaktionspartnern

Human SATB Homeobox 2 (SATB2) Interaktionspartner

SATB2 can be used as a supplementary marker along with CDX2 (zeige CDX2 Proteine) to identify 'colon-rectum' as the primary site in material from patients presenting with metastasis.

We describe the phenotype and genotype of 12 individuals with 10 unique (de novo in 11 of 11 tested) pathogenic variants (1 splice site, 5 frameshift, 3 nonsense, and 2 missense) in SATB2 and review all cases reported in the published literature caused by point alterations thus far

features associated with de novo mutations affecting SATB2 function in individuals ascertained on the basis of intellectual disability

The mRNA level of SATB2 was lower in tumor tissues than in samples of corresponding unchanged kidney. The results of the presented study suggest the tumor-suppressing function of SATB2.

We describe here the identification of a de novo SATB2 point mutation in twin boys with cleft soft palate, dental anomalies, and development delay and compare the clinical presentation of SATB2 point mutation patients reported to date.

Mouse (Murine) SATB Homeobox 2 (SATB2) Interaktionspartner

Together, these findings demonstrate that Satb2 is critically involved in long-term plasticity processes in the adult forebrain that underlie the consolidation and stabilization of context-linked memory.

Satb2 is a genetic determinant that mediates proper circuit development in a core sensory-to-motor spinal network.

A comprehensive overview of Satb2 expression in the adult mouse brain.

The Satb2 proteins are dispensable for X chromosome inactivation in mice.

SATB2 Protein Überblick

Protein Überblick

This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.