Key information relevant to the recruitment process for the
overall study, such as dates of the recruitment period and locations

Patients scheduled for living donor renal transplantation in the Department of Transplantation, Tongji Hospital, Huazhong University of Science and Technology were recruited in the project from May 2010 to November 2011.

Pre-Assignment Details

Significant events and approaches for the overall study
following participant enrollment, but prior to group assignment

68 pairs of patients were enrolled during the recruitment period. among them, 5 recipients had the history of renal transplantation before; 2 recipients had concomitant diabetes mellitus; and another one recipient had severe varicose vein in his lower limb. The left 60 pairs of donors and recipients (120 in total) were finally assigned to groups.

Reporting Groups

Description

Control

patients (both donors and recipients) had a deflated cuff placed on the left lower limb for 30 min

Donor RIPC

Donors receive remote ischaemic preconditioning after anaesthesia induction and before surgery started; recipients only have a deflated blood pressure cuff around their leg for 30 minutes.

Recipient PIPC

recipients receive remote ischaemic preconditioning after anaesthesia induction and before surgery started; donors only have a deflated blood pressure cuff around their leg for 30 minutes.

Explanation of how the number of participants for analysis was determined.
Includes whether analysis was per protocol, intention to treat, or another method.
Also provides relevant details such as imputation technique, as appropriate.

No text entered.

Reporting Groups

Description

Control

patients (both donors and recipients) had a deflated cuff placed on the left lower limb for 30 min.

Donor + RIPC

Donors receive remote ischaemic preconditioning after anaesthesia induction and before surgery started; recipients only have a deflated blood pressure cuff around their leg for 30 minutes.

Recipient +RIPC

recipients receive remote ischaemic preconditioning after anaesthesia induction and before surgery started; donors only have a deflated blood pressure cuff around their leg for 30 minutes.

Total

Total of all reporting groups

Baseline Measures

Control

Donor + RIPC

Recipient +RIPC

Total

Number of Participants
[units: participants]

20

20

20

60

Age
[1][units: years]Mean ± Standard Deviation

32.5
± 10.3

28.1
± 6.5

30.6
± 7.0

30.4
± 8.2

Age
[2][units: years]Mean ± Standard Deviation

46.9
± 6.4

47.4
± 10.0

48.7
± 5.2

47.6
± 7.4

Gender
[3][units: participants]

Female

4

4

6

14

Male

16

16

14

46

Gender
[4][units: participants]

Female

12

14

10

36

Male

8

6

10

24

Region of Enrollment
[units: donors/recipients pairs]

China

20

20

20

60

Body mass index (BMI)
[5][units: kg/m^2]Mean ± Standard Deviation

20.08
± 2.75

19.94
± 1.99

20.38
± 3.20

20.13
± 2.65

Cold ischemic time
[6][units: minutes]Mean ± Standard Deviation

175.65
± 36.35

166.25
± 19.22

177.25
± 27.59

173.05
± 28.52

Body mass index (BMI)
[7][units: kg/m^2]Mean ± Standard Deviation

22.19
± 3.51

22.19
± 2.43

23.45
± 2.61

22.61
± 2.90

Relationship
[8][units: donors/recipients pairs]

parents

12

16

14

42

siblings

6

2

5

13

spouses

2

2

1

5

[1]

Age of the recipient

[2]

Age of the donor

[3]

Gender of the recipient

[4]

Gender of the donor

[5]

BMI of the recipient. BMI=weight(kg)/〖height(m)〗^2

[6]

Time from fully perfusion of the donor kidney to complement of the artery unclamping in the transplantation surgery