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... not OBSERVED. No, this paper by Demuth et al. (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0000085) reports that "expansions outnumber contractions on the human, chimp, mouse, rodent, and ingroup branches" and that "Along the lineage leading to humans, ...

... not OBSERVED. No, this paper by Demuth et al. (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0000085) reports that "expansions outnumber contractions on the human, chimp, mouse, rodent, and ingroup branches" and that "Along the lineage leading to humans, ...

... are now called protein bodies) are specialized vacuoles, that are filled with proteins and a phytin salt. Spherosomes are not vacuoles. They are expansions of the endopasmic reticulum that store lipids. Let me know if you have other questions.