Quality Open Access Research

Brain and Behavior – Issue 2.3 Now Live!

‘Effects of cranial electrotherapy stimulation on resting state brain activity’ by Jamie D. Feusner, Sarah Madsen, Teena D. Moody, Cara Bohon, Emily Hembacher, Susan Y. Bookheimer and Alexander BystritskyAbstract: The goal of this study was to characterize the acute effects of cranial electrotherapy stimulation (CES), an FDA-approved treatment for insomnia, depression, and anxiety consisting of pulsed, low-intensity current applied to the earlobes, on resting state brain activity. Using fMRI simultaneously with stimulation, we found that both 0.5-Hz and 100-Hz stimulation resulted in significant deactivation in midline frontal and parietal regions, and 100-Hz stimulation was associated with alterations in connectivity within the default mode network. These results provide insight into the mechanism of action of CES, and may assist in the future development of optimal parameters for effective treatment.

‘Contemporary use and practice of electroconvulsive therapy worldwide’ by Kari Ann Leiknes, Lindy Jarosh-von Schweder and Bjørg HøieAbstract: The focus of this systematic review is on contemporary (from 1990) use and practice of electroconvulsive therapy (ECT) worldwide. Seventy studies were included: 7 from Australia and New Zealand, 3 Africa, 12 North and Latin America, 33 Europe and 15 Asia. Many patients are still ECT treated without anesthesia today. Large global variation in ECT utilization, administration and practice advocate a need for worldwide sharing of knowledge about ECT, reflection, and learning from each other experiences.

Enjoy these and the other articles in this issue. To find out when other issues publish sign up for e-toc alerts!
1. Go to the Brain and Behavior homepage.
2. click on
3. Register or Log in: when prompted, log in to your Wiley Online Library account. If you need to create an account, register for free!