In this video Dr. Jude Fitzgibbon, Barts Cancer Institute, Queen Mary University of London, discusses his work on the molecular pathogenesis of hematological malignancies. Jude tells SelectScience how his laboratory has developed one of the largest series of sequential tumor tissue worldwide and this enables him to trace the genetic changes in these tumors over time. Jude explains how he has identified several epigenetic changes that are responsible for the onset and potential severity of Follicular Lymphoma, an incurable B cell malignancy.