This primary role for the spinal cord lesion is further supported by the tendency of forelimbs and hind limbs to be affected bilaterally because muscle involvement might be expected to lead to more randomly distributed lesions.

However, the non- significant differences observed in the NCV of right and left sciatic nerves of Uromastix and Rabbit (Table 1), indicate non-preference in the use of right or left hind limb in the two animals during crawling or hopping movements, respectively.

In the study to be presented, which follows on from a series of successful earlier pre-clinical efficacy studies undertaken by the Bristol team, ReNeuron's lead CTX stem cell line was tested in a recognised diabetic mouse model of hind limb ischemia.

The venom, delivered by a spur in the hind limb, is not powerful enough to kill a human, but can immobilize smaller animals and can cause enough pain to allow the platypus to escape an unwanted encounter with such predators as cougars or huskies.

One animal had a third hind limb and was submitted for analysis for trematodes, a possible cause of extra hindlimbs, but showed no signs of trematodes at the limb base at the time of necropsy (Sessions and Ruth 1990).

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