2018 Experiential Intern (Graduate Level) - Solid State Chemistry

The AbbVie Experiential Internship Program
As an AbbVie Experiential Intern, you'll participate in a paid, ten to twelve-week summer program that is focused on providing students with robust projects throughout the summer. As an intern, you will be located at our corporate headquarters in north suburban Chicago, with housing and shuttle services for eligible students.
Department Overview - Solid State Chemistry
Solid State Chemists at AbbVie work in cross-functional teams to support projects through all phases of development (Lead Optimization to Process Validation). In early development, they identify commercial solid form of the API and develop scalable API isolation processes for early clinical studies. During Phase II, they work with engineers and formulation scientists to establish structure-property-performance correlations and deliver commercial API isolation processes with optimized physical properties. In the final stages of development, solid-state chemists help align control strategies across API and drug product and transition isolation processes and relevant physical characterization methods into commercial manufacturing sites. Throughout development, they work with relevant teams to ensure successful regulatory submissions. In order to develop and implement robust solutions, Solid State Chemists at AbbVie use a very diverse set of experimental, analytical and modeling techniques and tools.
Assignment Details
The intern will focus on advancing our knowledge in pharmaceutical solids to address challenges in drug substance manufacturing and processing. Specifically, the researcher will develop new tools for solid form development, leveraging advanced characterization techniques, PAT tools and in-silico modeling approaches. The researcher will also have opportunity to work in dynamic R&D teams to help implementing the modeling tools in real world drug development programs. Verification of computational results with experimental approaches may also be performed as a part of the overall project.

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QualificationsBasic:

Completed at least one year of college education before beginning internship

Must be enrolled in school the semester following your internship

Graduate Level Student majoring in advanced knowledge of molecular modeling of organic crystals, including but not limited to force fields, energy minimization, molecular dynamics, and

Minimum Cumulative GPA: 3.0/4.0

Must be authorized to work in the U.S. on a permanent basis without requiring sponsorship (students on an F1 visa with CPT can be accommodated).

Preferred:

Knowledge of crystal morphology modeling, growth mechanisms and Material Studio is a plus.