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Something will be different when the Colts play Houston on Sunday night.

For the first time since Dec. 27, 1998, the Colts will take the field without either Reggie Wayne or Marvin Harrison in the lineup. That's 251 games, including the playoffs, with either No. 87 or No. 88 - or both - on the field.

Wayne's streak of 189 regular-season appearances, 207 including the postseason, will end Sunday due to a torn anterior cruciate ligament in his right knee suffered against Denver. ...