STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Dehly_0987

Glutamate synthase (501 aa)

Predicted Functional Partners:

Dehly_0986

Glutamate synthase subunit alpha domain-containing protein (254 aa)

0.999

Dehly_0989

Glutamine amidotransferase (380 aa)

0.998

Dehly_0559

Glutamine synthetase (446 aa)

0.970

Dehly_1485

Glutamine synthetase (500 aa)

0.959

Dehly_0990

FAD-dependent pyridine nucleotide-disulfide oxidoreductase (430 aa)

0.939

Dehly_0499

Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (394 aa)

0.926

Dehly_0992

4Fe-4S ferredoxin (155 aa)

0.921

Dehly_1208

Glutamate synthase (466 aa)

0.919

Dehly_0658

Adenylosuccinate lyase (451 aa)

0.892

hisF

Imidazoleglycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (252 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

Dehly_0499

Dehly_0986

Dehly_0499

Dehly_0986

Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

Glutamate synthase subunit alpha domain-containing protein

0.907

Dehly_0499

Dehly_0987

Dehly_0499

Dehly_0987

Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

Glutamate synthase

0.926

Dehly_0499

Dehly_0989

Dehly_0499

Dehly_0989

Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

Glutamine amidotransferase

0.907

Dehly_0499

hisF

Dehly_0499

Dehly_0988

Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

Imidazoleglycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit

0.564

Dehly_0559

Dehly_0986

Dehly_0559

Dehly_0986

Glutamine synthetase

Glutamate synthase subunit alpha domain-containing protein

0.959

Dehly_0559

Dehly_0987

Dehly_0559

Dehly_0987

Glutamine synthetase

Glutamate synthase

0.970

Dehly_0559

Dehly_0989

Dehly_0559

Dehly_0989

Glutamine synthetase

Glutamine amidotransferase

0.613

Dehly_0559

Dehly_0992

Dehly_0559

Dehly_0992

Glutamine synthetase

4Fe-4S ferredoxin

0.414

Dehly_0559

Dehly_1208

Dehly_0559

Dehly_1208

Glutamine synthetase

Glutamate synthase

0.926

Dehly_0559

Dehly_1485

Dehly_0559

Dehly_1485

Glutamine synthetase

Glutamine synthetase

0.852

Dehly_0658

Dehly_0987

Dehly_0658

Dehly_0987

Adenylosuccinate lyase

Glutamate synthase

0.892

Dehly_0658

hisF

Dehly_0658

Dehly_0988

Adenylosuccinate lyase

Imidazoleglycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit

0.827

Dehly_0986

Dehly_0499

Dehly_0986

Dehly_0499

Glutamate synthase subunit alpha domain-containing protein

Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

0.907

Dehly_0986

Dehly_0559

Dehly_0986

Dehly_0559

Glutamate synthase subunit alpha domain-containing protein

Glutamine synthetase

0.959

Dehly_0986

Dehly_0987

Dehly_0986

Dehly_0987

Glutamate synthase subunit alpha domain-containing protein

Glutamate synthase

0.999

Dehly_0986

Dehly_0989

Dehly_0986

Dehly_0989

Glutamate synthase subunit alpha domain-containing protein

Glutamine amidotransferase

0.999

Dehly_0986

Dehly_0990

Dehly_0986

Dehly_0990

Glutamate synthase subunit alpha domain-containing protein

FAD-dependent pyridine nucleotide-disulfide oxidoreductase

0.920

Dehly_0986

Dehly_0992

Dehly_0986

Dehly_0992

Glutamate synthase subunit alpha domain-containing protein

4Fe-4S ferredoxin

0.898

Dehly_0986

Dehly_1208

Dehly_0986

Dehly_1208

Glutamate synthase subunit alpha domain-containing protein

Glutamate synthase

0.759

Dehly_0986

Dehly_1485

Dehly_0986

Dehly_1485

Glutamate synthase subunit alpha domain-containing protein

Glutamine synthetase

0.959

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: