But if any skillful minister of nature shall apply force to matter, and by design torture and vex it, in order to [effect] its annihilation, it, on the contrary being brought under this necessity, changes and transforms itself into a strange variety of shapes and appearances; for nothing but the power of the Creator can annihilate, or truly destroy it.

It sometimes strikes me that the whole of science is a piece of impudence; that nature can afford to ignore our impertinent interference. If our monkey mischief should ever reach the point of blowing up the earth by decomposing an atom, and even annihilated the sun himself, I cannot really suppose that the universe would turn a hair.

Modern anthropology has taught us, through comparative investigation of so-called primitive cultures, that the social behavior of human beings may differ greatly, depending upon prevailing cultural patterns and the types of organisation which predominate in society. It is on this that those who are striving to improve the lot of man may ground their hopes: human beings are not condemned, because of their biological constitution, to annihilate each other or to be at the mercy of a cruel, self-inflicted fate.

Our factories may well put an end to war sooner than your (peace) congresses. The day when two army corps can annihilate one another in one second, all civilized nations, it is to be hoped, will recoil from war and discharge their troops.

What is a scientist? We give the name scientist to the type of man who has felt experiment to be a means guiding him to search out the deep truth of life, to lift a veil from its fascinating secrets, and who, in this pursuit, has felt arising within him a love for the mysteries of nature, so passionate as to annihilate the thought of himself.

In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion.
(1987) -- Carl Sagan