Kevin Durant has withdrawn from the U.S. national team, the biggest loss yet for a weakening American team.

The NBA's MVP informed USA Basketball on Thursday that he was "physically and mentally drained from the NBA season," USA Basketball chairman Jerry Colangelo said in a statement.

The Oklahoma City Thunder star was the MVP of the world championship in 2010, leading the Americans to that title for the first time since 1994. He also started on their gold medal-winning team in the 2012 Olympics.