Sharma S, Saxena P., Systems
biology prediction of evolutionary process for coloured vision in mammals, Onl J Bioinform, 16 (1): 1-7, 2015. Since Darwin, genetic change has been
considered to be a direct indicator of variation in phenotype. Recently it has
been proposed that epigenetic developmental processes affect phenotype shifting
focus from a linear genotype-phenotype map to a non-linear G-P one. LWS opsin
gene has a role in trichromatic vision in human beings and other mammals. LWS
opsin gene is particularly sensitive to the green-yellow color
range differentiating between vivid colors more
clearly. We describe evolution of colour vision in mammals through the LWS
long-wave sensitive gene mutations which lead to the different phenotypes. The
opsin genes LWS, MWS and SWScontribute to a variable colour vision spectrum and we show that
genotypic variation alone is not responsible for resulting genotypes in vision.