DAMP-Mediated Autophagy Contributes to Drug Resistance
High mobility group box 1 (HMGB1) is a prototypical damage associated molecular pattern molecule (DAMP) and is associated with the hallmarks of cancer. Recently researchers found that HMGB1 release after chemotherapy treatment is a critical regulator of autophagy and a potential drug target for therapeutic interventions in leukemia. [Autophagy]

Bayer, J&J Anti-Clot Drug Shines in Stroke Trial
A once-daily pill being developed by Bayer AG and Johnson & Johnson was better at preventing stroke than standard treatment, with less risk of the most worrisome types of bleeding, researchers said. [Reuters]