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Supplements aimed to increase testosterone and reduce estrogen, are often multi-component mixtures of plant extracts. The first place is taken by Tribulus terrestis, which directly increases testosterone, and therefore also has all the characteristics assigned to that hormone. Other substances are mainly the following: nettle, which has the ability to increase the free testosterone, triiodothyronine and IGF-1; fenugreek, which has anti-estrogen and pro-testosterone properties; indoles, which are blocking estrogen and lowering the risk of gynecomastia and resveratol, which is showing a strong antioxidant and anti-estrogen properties.