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Defining Conflict of Interest “A conflict between private interests and the official responsibilities of a person in a position of trust” – Merriam-Webster “…a divergence between an individual’s private, personal relationships or interests and his/her professional obligations to the university such that an independent observer might reasonably question whether the individuals professional actions or decisions are determined by considerations of personal benefit, gain or advantage” – KS Board of Regents Policy Manual

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Defining Conflict of Interest “…when the Institution’s designated official(s) reasonably determines that a Significant Financial Interest…could directly and significantly affect the design, conduct, or reporting of NIH-funded research” - National Institutes of Health Financial relationships are not necessarily inappropriate or bad. It’s when they are not reported and managed that problems arise.

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Current Case: NIH/Sunderland Dr. Pearson Sunderland, III, sr. scientist at National Institute of Mental Health Supervised NIMH’s geriatric research Collaborative biomarker research with Pfizer $300,000 for consulting from Pfizer; did not report it Was required to report arrangements >$260 2 years probation, forfeit $300K, 400 hours of community service

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Current Case: UT/Wagner Dr. Karen Wagner, child psychiatrist at UT Medical Branch at Galveston Served on the university’s COI committee GSK Paxil study for teenage depression Wagner was one of GSK’s “opinion leaders” Co-author on study that overstated Paxil’s safety $160,000 from Pfizer over 6 years; $76,241 of the total was related to Paxil consulting