Old Dominion (8-4), which ranks second nationally in scoring defense, took a 30-10 lead en route to a 40-13 halftime margin. The 49ers shot 16 percent from the floor in the first half (4-for-25) to the Monarch's 58.1 percent (18-for-31).

Charlotte (9-2) improved to 48.3 percent (14-for-29) in the second half, but could get no closer than 25 points and trailed by as many as 37.

The Monarchs outrebounded the 49ers 47-26 and had 24 assists.

Shamari Spears, Charlotte's leading scorer at 17.9 points per game, had 12 points while DiJuan Harris, who had been averaging 10.6 points per game, scored one point.