The following rules shall be
applied on the day of donation by trained persons and results shall be recorded
(See Section 490.440 of this Part).

a) The following requirements shall apply to determine donor
suitability.

1) Prospective donors with a history of chronic disease of the
heart, kidneys, lungs, liver, etc.; or with a history of cancer, except minor
skin cancer; or abnormal bleeding tendencies; shall be excluded subject to
evaluation by a physician on the day of donation.

2) The interval between individual donations shall be at least 8
weeks.

3) The amount of whole blood (not including anticoagulant)
removed from a donor during a plasmapheresis procedure or in any 48-hour
period, shall not exceed 1,000 ml unless the donor's weight is 80 kg (176
pounds) or greater. If the donor's weight is 80 kg or greater, the amount of
whole blood removed during a plasmapheresis procedure or in any 48-hour period
shall not exceed 1,500 ml. Within a 7-day period, the amount of whole blood
removed shall not exceed 2,000 ml. unless the donor's weight is 80 kg (176
pounds) or greater, in which case it shall not exceed 2,400 ml.

b) The donor shall be free of disease transmissible by blood
transfusion as ascertained at the time of collection in accordance with the
guide for donor requirements. (See subsection (c) of this Section).

c) If the following requirements are not met, the donor shall be
rejected.

1) General Appearance

The donor shall appear to be in good health and free from
acute respiratory diseases.

2) Age

Blood donor shall be between the ages of 17 through 75 (up to
76th birthday) provided:

A) that the donor is 17 years of age or older

B) after the 76th birthday, donors may be accepted at
the discretion of the blood bank director if they have specific written consent
from a physician within two (2) weeks before the date of donation, and they
meet all other criteria for acceptability (See Section 490.40(c)(5) of this
Part).

Prospective donors who during the preceding six months have
received blood or human blood components known to be a possible source of
hepatitis, shall be excluded.

9) Infectious Diseases

A donor shall be free from infectious diseases known to be
transmissible by blood insofar as can be determined by usual examinations and
history as indicated below.

A) Viral Hepatitis

i) Prospective donors with a history of viral hepatitis shall be
excluded.

ii) A prospective donor shall be excluded permanently if the
donor's blood was the only unit of blood or blood component administered to a
patient who within six months developed posttransfusion hepatitis and who
received no other blood derivative known to transmit vital hepatitis and there
was no other probable source of infection.

iii) A prospective donor shall be excluded permanently if the
donor has a history of a reactive test for hepatitis B surface antigen.

iv) When hepatitis has developed after transfusion of blood, blood
components, or derivatives from multiple donors, those donors who have not been
previously suspected of hepatitis need not be rejected as future donors of
whole blood. Each situation should be evaluated individually by the blood bank
physician.

B) Travelers who have been in areas considered endemic for malaria
by the Malaria Branch, Centers for Disease Control, U.S. Department of Health
and Human Services, may be accepted as regular blood donors six months after
return to the nonendemic area, providing they have been free of unexplained
febrile illnesses and have not taken antimalarial drugs. Prospective donors
who have had malaria shall be deferred for three years after becoming
asymptomatic and after cessation of therapy. Prospective donors who have taken
antimalarial prophylaxis or who have been in an endemic area shall be deferred
for three years after cessation of therapy or after departure from the area if
they have been asymptomatic in the interim. Immigrants or visitors from endemic
areas may be accepted as blood donors three years after departure from the area
if they have been asymptomatic in the interim. Donations to be used for the
preparation of plasma, plasma components or derivatives devoid of intact red
blood cells are exempted from these restrictions.

C) Syphilis

A donor whose blood tests positive for syphilis shall be
rejected. Prospective donors may be acceptable when they become seronegative
upon approval by the blood bank medical director.

D) Tuberculosis

Prospective donors with clinically active tuberculosis are
unacceptable. Prospective donors with a positive tuberculin skin test, but
without underlying medical conditions, may be accepted if they have not taken
prophylactic medication during the preceding 48 hours.

E) HIV Infection

i) Blood and blood components which have been found reactive
when tested for evidence of infection with the human immunodeficiency virus
(HIV) or any other identified causative agent of AIDS shall be rejected for
blood donation in accordance with Section 490.750(b).

ii) Prospective donors who request that their blood be tested for
evidence of infection with HIV shall be referred to a HIV Counseling and
Testing Center designated by the Illinois Department of Public Health.

10) Immunizations or vaccinations:

A) Persons recently immunized with toxoids and killed virus,
bacterial and rickettesial vaccines are acceptable, if they are symptom-free
and afebrile. These include vaccines against hepatitis B, tetanus, diphtheria,
pertussis, typhoid, paratyphoid, cholera, typhus, Rocky Mountain spotted fever,
influenza, polio (injection) and plague. The same rules apply for rabies
vaccine (duck embryo or human diploid) unless the vaccination has been given
following a bite by a rabid animal in which case the donor is deferred until 1
year after the bite.

B) After vaccination for smallpox, donors are acceptable when the
scab has fallen off or 2 weeks after an immune reaction. Following inoculation
with attenuated virus vaccines such as polio (oral), measles (rubeola), mumps
or yellow fever, donors are deferred for 2 weeks; following inoculation for
German measles (rubella), deferral is for 4 weeks.

The skin at the venipuncture site shall be free of lesions
and no tattoo was performed any place on the body within six months prior to
donation.

12) Alcohol, narcotics

Obvious stigmata of narcotic or alcoholic habituation or
intoxication shall exclude a donor.

13) Oral medication

History of recent drug therapy shall be evaluated by a
physician since the indication for such treatment may be cause for donor
rejection. Exceptions to this requirement include ingestion of vitamins or oral
contraceptives.

14) Therapeutic bleedings

Any blood withdrawn from a person for a therapeutic purpose
and intended for future homologous transfusion shall be labeled to indicate the
donor's disease. Therapeutic bleedings shall be performed only at the written
request of a person's physician. The blood bank medical director shall decide
whether the person will be bleed in the blood bank. The use of this blood for
transfusion purposes shall be determined by the physician in charge of the
blood bank and of the physician attending the prospective recipient.

15) Weight and amount of blood

Donors weighing 110 lbs (50 kg) or more may ordinarily give
450 plus or minus 45 ml of blood, in addition to pilot samples which shall not
exceed 30 ml. Donors weighing less than 110 lbs may be bled proportionately
less in a reduced volume of anticoagulant, except that it is not necessary to
reduce the amount of anticoagulant calculated for 450 ml of blood when the
amount of blood drawn is 300 ml to 405 ml. Prospective donations of blood
exceeding the recommended amounts shall be subject to evaluation by a
physician.

16) Medical discretion

Any of the above criteria may be waived or modified by the
medical director and the donor's physician, for certain medical indications
related to the therapy of the donor.

d) Before any blood is collected, all donors shall be informed
that:

1) Each unit of donated blood will be tested for the presence of
antibodies to HIV or any other identified causative agent of AIDS.

A) All donors shall be informed about the following:

i) The meaning of the HIV test results, such as the purpose,
potential use, limitations of the test and test results; the use of additional
confirmatory testing and the related notification procedures; and the
availability of referrals for further information and counseling.

ii) The opportunity to refuse HIV testing. If testing is
refused, then the person will not be accepted as a donor.

B) Collection of a donor's blood is not permitted without signed
written consent of the donor allowing disclosure of the test results to the
donor. However, the written informed consent required by AIDS Confidentiality Act
Ill. Rev. Stat 1987, ch. 111½, par. 7301 et seq.) and 77 Ill. Adm. Code 697.120
is not necessary because blood donors are specifically required by law to be
tested.

2) Persons infected with HIV are potentially infectious to
persons with whom they have contact through sexual relations or the sharing of
blood or blood components. Persons with increased risk (high risk) of being
infected with HIV virus must not donate blood, except for the purpose of
autologous transfusion. High risk persons include the following:

A) persons who have signs and symptoms suggestive of Acquired
Immunodeficiency Syndrome (AIDS) (e.g. a combination of two or more than the
following: unexpected weight loss of greater than 10% of body weight, chronic
fever, chronic lymphadenopathy, night sweats or chronic diarrhea);

B) persons who have had sexual contact with the HIV
infected-persons;

C) males who have sexual contact with a male anytime since 1977;

D) persons who have immigrated from countries where heterosexual
activity is thought to play a major role in transmission of HIV infection, such
as Central Africa and Haiti anytime since 1977 as recognized by the Centers for
Disease Control;

3) Confirmed, available, test results showing evidence of HIV
infection (e.g. Western blot assay or Indirect Fluorescent Antibody tests) will
be disclosed in a confidential manner to the donor's physician or the donor no
later than 55 days after the date of donation as described in Section
490.750(b) of this Part.