英文摘要：General anesthesia is a situation with drug-induced inhibition of central nervous system which can be used for long-term operation procedures and invasive experiments. The thalamo-cortical loop, especially the thalamus, is supposed to play a role in anesthesia-awakening regulation, however, whether the thalamus is the most important brain region and this regulation is asymmetric remain unclear. The present study used the south African clawed frog (Xenopus laevis) as an animal model, and 6 cortical electrode pairs were implanted on the frog skull:both sides of the telencephalon, diencephalon and mesencephalon, respectively. The frogs were immersed in triciane methanesulfonate for general anesthesia and the electroencephalogram signals were recorded for the "pre-anesthesia, administration, recovery and post-anesthesia" cycle continuously. Lempel-Ziv complexity (LZC) was calculated for each stage. The results showed that LZC values differed significantly among various stages, and the highest values occurred during the awakening period and the lowest values occurred during the anesthesia period; and significant correlations were found exclusively between the duration of administration stage and LZC values for the right hemisphere, especially for the right thalamus. These results suggested that the anesthesia-awakening cycle could be reflected by LZC, and the right thalamus might play an important role in anesthesia-awakening regulation.