Smiths Falls Mayor Dennis Staples said he was "thrilled" when Tweed Inc. suggested the idea for the plant that has been vacant since 2008. The plant's previous owner Icon International had plans for demolition.

"We would have seen the plant disappear and that would have been a huge opportunity lost," Staples said.

Medical marijuana has been legal in Canada since 2001 and the number of patients prescribed to use it has grown beyond 30,000. Residents of Smiths Falls are comfortable with the new business venture, said Staples.

"I've had nothing but positive comments," he said. "It's going to happen somewhere in Canada so why not in Smiths Falls?"

Tweed Inc. expects $100M revenue annually

Tweed Inc. purchased the old chocolate factory last year and has already started growing 25 different strains in its 168,000 square-foot facility, said CEO Chuck Rifici.

Patients can register as soon as Feb. 6 to have product delivered directly to their home, Rifici said.

"There are no retail operations. So all competitors are competing for customers around Canada. There's very little geographic advantage other than perhaps a smaller shipping delay or a smaller shipping cost between different locations," he said.

Chuck Rifici expects Tweed Inc. to generate more than $100 million of revenue annually once the medical marijuana facility in the old chocolate factory in Smiths Falls is operating at full capacity. (CBC)

The challenge now is to build its reputation and brand by word of mouth, he said.

"It's difficult. It's a new business but we cannot advertise. It is a narcotic," he said. "The road ahead is really making sure that we have a quality medicine, quality product and variety that we think patients will be happy with."

Medical marijuana will be priced between $7 to $12 a gram depending on the strain, which Rifici believes is similar to the street value of marijuana. The plant is expected to generate "well over" $100 million in revenue annually once it is operating at full capacity, Rifici said.

Now that it has a licence, Tweed is seeking a listing on the TSX Venture Exchange.