Department of Molecular Medicine

Faculty

Joseph Kissil, PhD

ProfessorDepartment of Molecular MedicineFlorida Campus

Scripps Research Joint Appointments

Faculty, Graduate Program

Research Focus

Studies over the past several years have demonstrated that pathways regulating processes such as cell fate decisions and organ size control, during development, also play pivotal roles during tumorigenesis. While many of the individual signal transduction pathways have been outlined, a major ongoing challenge has been to integrate these findings into a comprehensive map of cellular signaling networks. Our lab is studying the signal transduction pathways regulated by small GTP-binding proteins from the Ras and Rac families and how these pathways crosstalk with pathways controlling cell fate and organ size control, such as the Notch, Wnt and Hpo/YAP pathways.

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