Bell and Riddick had already been ruled out for the game, leaving the Lions woefully thin at running back behind Reggie Bush. Fauria and Lewis had also been ruled out, while Vaughn was doubtful to play. Calvin Johnson, who was listed as questionable, is active and ready to roll.

Lions CB Cassius Vaughn listed as doubtful Week 5

Vaughn is dealing with an ankle injury. After not participating in practice Wednesday, Vaughn was able to get through limited work both Thursday and Friday.

Lions CB Cassius Vaughn seeking role for Sunday

by Marty Gitlin | CBSSports.com

(10/2/14) Lions nickel cornerback Cassius Vaughn is hoping to return to action Sunday against Buffalo after missing two games with an ankle injury. But he realizes his hopes might conflict with reality.

Vaughn has made progress since suffering the injury on Sept. 17. But he might be deemed unready to play and might also no longer have a defined role, according to the Detroit Free Press.

"I'm trying to sweet talk them and see (if I can play this week)," Vaughn said. "I know the coaching staff believes in me and I know we're trying to get back, but when we're on a run like this and you're seeing the team doing so well, you just want to be a part of it."

Vaughn assumed the nickel role early in Week 2 after rookie Nevin Lawson sustained a season-ending injury. Vaughn was slated for slot duty against Green Bay the next week, but sprained his ankle in practice and has been sidelined since.