RPR Card antigen suspension is a carbon particle cardiolipin antigen1 which detects reagin, an antibody-like substance present in serum or plasma from syphilitic persons, and occasionally in serum or plasma of persons with other acute or chronic conditions. The reagin binds to the test antigen, which consists of cardiolipin-lecithin-coated cholesterol particles, causing macroscopic flocculation.

CLIA Complexity: Moderate

Nontreponemal test

For the serological detection of syphilis as described in A Manual of Tests for Syphilis†

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