One member of this family, as characterised in Klebsiella terrigena[], is able to interconvert acetoin + NADH with meso-2,3-butanediol + NAD(+). It is also capable of irreversible reduction of diacetyl with NADH to acetoin. There has been a reuctance to classify the enzyme as either , which is (R,R)-butanediol dehydrogenase, or , which is acetoin dehydrogenase without a specified stereochemistry []. Another member of this family, from Corynebacterium glutamicum(Brevibacteriumflavum), is called L-2,3-butanediol dehydrogenase [].This enzyme is a homotetramer in the family of short chain dehydrogenases().

This database is part of a project that received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement number 649024).