comment:

Ovarian osseous metaplasia (
Figure 1
and
Figure 2
) is characterized by a well-circumscribed, unencapsulated focus composed of bony trabeculae lined by osteoblasts and osteoclasts; there may also be clumps of amorphous acellular basophilic material, which are most likely mineralized deposits of calcium salts, and mild compression of adjacent ovarian parenchyma. Ovarian metaplasia is a change associated with aging and ovarian atrophy. Osseous metaplasia has been occasionally reported, but the mechanism has not been elucidated.