Primary squamous cell(epidermal) carcinomas of the head and the neck cancer, excluding the lip.

Melanoma

Dosage :

ADULTS : Initial doses is 150 mg/m2 once daily for 5 consecutive days per 25 days treatment.INTERMITTENT THERAPY : 80mg/kg administered orally as a single dose every third day.CONTINUOUS THERAPY : 20 to 30 mg/kg administered orally as a single dose daily.