Histology Controls

References

Reviews

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The product of the RIPK3 gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The RIP3 protein is predominantly localized to the cytoplasm, and can undergo nucleo-cytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor (provided by RefSeq, Jul 2008).

Mouse anti Human RIP3 antibody detects a band of 57 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species

Human

Western Blotting

Anti RIP3 detects a band of approximately 57 kDa in Jurkat cell lysates

Anti RIP3 detects a band of approximately 57 kDa in Jurkat cell lysates

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name

Yes

No

Min Dilution

Max Dilution

Western Blotting

1/1000

Application Name

Yes

No

Min Dilution

Max Dilution

Western Blotting

1/1000

PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.