Borussia Dortmund captain Marco Reus has been ruled out of the first leg of the Champions League last-16 tie at Tottenham Hotspur on Wednesday due to a thigh injury, the club said.

Reus, who has 17 goals for Dortmund in all competitions and is the club’s leading scorer, injured his thigh during his side’s German Cup defeat by Werder Bremen last week and missed the draw with Hoffenheim in the league at the weekend, Reuters reported.

“We would, of course, have liked to have him in London, because his presence is a bit intimidating for the opponent,” Dortmund official Sebastian Kehl told reporters. “But we’ll compensate for his absence.”

Jadon Sancho, the 18-year-old English winger who has eight goals and 10 assists in all competitions, is expected to take Reus’ place in the starting lineup.