It cannot be sex liked. It's not X-linked because that scenario it would NOT be passed from father to son and it is. It's not Y-linked because in that case, it would ONLY be passed from father to son (not the case here). It cannot be dominant because that requires that at least one parent of each affected individual be also affected. Again, not in this case. So, that leaves #3...

first of all thanks, second I also thought that this is the answer, but my doctor published her answers and according to her the answer is 4-autosome dominant which appears only in males.that means the first male must be homozygote recessive and the first female must hetrozygote, but as we can see she isn't a carrier.So if my doctor is right, could it be that the female is not marked in black because this affect only males? I mean this is possible that one sex have a dominant allele but becase the sex it doesn't appears?

I suppose that is possible theoretically. However, this pedigree in itself is insufficient to conclude one way or another. Also, you did not provide what condition we are talking about. Is it something male-specific? If you want, provide the link to publication you are talking about so we could discuss some more...

If it was recessive, you would see the pattern of every-other generation, but you see affected people in every generation, thus it is dominant affecting only men (and that's the reason, why you do not see affected parents of affected children)

If it's related to something male-specific, then you will hardly see it in women (as the mentioned sperm production). And in such case, although mother should be affected, you do not see it, so she seems like healthy, although she's not.

JackBean wrote:If it's related to something male-specific, then you will hardly see it in women (as the mentioned sperm production). And in such case, although mother should be affected, you do not see it, so she seems like healthy, although she's not.

That is the main problem. It's not sperm production as males are fertile according to pedigree. It's said to be a rare disease, so can you think of any male specific disease that autosomal? I sure cannot think of anything.