Studs Terkel discusses the upcoming new film "Of Mice and Men", based on the novel written by John Steinbeck with the starring actors, John Malkovich (Lennie) and Gary Sinise (George). The program begins with the opening excerpt from the play "Of Mice and Men" featuring Terkel (George) and Win Stracke (Lennie) from 1952, which then leads into Malkovich and Sinise's interpretation of the rest of the scene. Folk singer Utah Phillips song "On the Goodnight Loving Trail" is presented as a comparison to themes expressed in "Of Mice and Men".

Maxine Andrews reminisces over Andrew Sisters songs with Studs Terkel. She acknowledges the heavy influence the Boswell Sisters played in the creation of their image. She relays musical stories surrounding songs in Abbott and Costello such as "Bugle Boy" from their movie "Buck Privates". How they found the song "Mir Bist Du Schon" and Sammy Cahn and Saul Chaplin helped with the lyrics. How song pluggers brought The Andrew Sisters "Tip-Pi-Tin". How "Apple Blossom Time" helped an injured soldier at Oak Knoll Hospital upon his return to the states.