Many authorities around the world have looked at the effects of caffeine. The European Food Safety Authority (EFSA) concluded in its scientific opinion on the safety of caffeine (2015) that caffeine intake of up to 400 mg per day (five 250 ml cans or five cups of coffee) does not raise safety concerns for the general healthy adult population. This is in line with similar findings from the US Food and Drug Administration and Health Canada. However, pregnant and breast-feeding women should limit their caffeine intake to 200 mg.