Thermo Scientific™ dialysis units help facilitate the rapid and trouble-free dialysis of sample volumes from 10 μL to 250 mL. Unlike standard flat tubing, these innovative devices do not require knots or clips that can lead to leaking and sample loss.

Pierce™ 96-well Microdialysis Plates and Slide-A-Lyzer™ Dialysis MINI Devices are ideal for small volumes, Slide-A-Lyzer™ Dialysis Cassettes (original and G2) are recommended for small to medium volumes, and Slide-A-Lyzer™ Dialysis Flasks are recommended for larger volumes.

Thermo Scientific™ Slide-A-Lyzer™ Cassettes protect your precious samples during dialysis and help minimize the hassles and risks of losing your samples using slippery tubing. They're available in sizes from 10 µL to 250 mL and in a full range of MWCOs.

Traditional tubing

vs.

Cassette

Slippery when wet Flat tubing is difficult to handle when wet, increasing risk of sample loss during sample addition/removal

Thermo Scientific Slide-A-Lyzer Flasks Video

Dialyze large-volume samples (150 to 250mL) without dialysis tubing or bags with these flask-style, screw-cap dialysis bottles.Do you need to dialyze a large-volume sample? Thermo Scientific Slide-A-Lyzer Dialysis Flasks remove salts and small-molecule contaminants from sample volumes of up to 250mL by providing a large membrane surface area for dialysis and the structural support for easy handling. To dialyze your sample, first hydrate the membranes by placing the included float ring around the neck of the dialysis flask, unscrewing the cap and completely submerging the membranes in dialysis buffer for 2 minutes. After hydrating, gently tap the plastic body of the flask on a paper towel to remove excess liquid without drying or damaging the membranes. Pipette or pour your sample into the flask through the wide-mouth opening, remove excess air from the flask by gently squeezing the membranes, cap the flask, and float it in dialysis buffer. A typical protocol begins by dialyzing the sample for 2-3 hours at room temperature or in a cold room. After changing the dialysis buffer and dialyzing for another 2-3 hours, change the buffer again and dialyze overnight. Remove the flask from the buffer and inspect it for swelling caused by the net influx of water. If the flask has swollen, relieve the pressure on the membranes by removing some of the sample using a syringe inserted through the port on the cap. Then unscrew the cap and collect your dialyzed sample.

Other featured dialysis products

A ready-to-use form of traditional dialysis membrane tubing for 10 to 100 mL samples that does not require presoaking or boiling prior to use. SnakeSkin™ Dialysis Tubing is composed of regenerated cellulose and is available in 3 molecular weight cutoffs and 3 internal diameters.