This poster presents a study to collect and characterize specimens from febrile patients who were suspected to have malaria, pedigree specimens against a panel of nucleic acid and serological markers, and draw early insights into data that would be generated by a multiplex diagnostic platform. Presented at The American Society of Tropical Medicine and Hygiene, December 7, 2008; New Orleans, LA.

This issue of Directions in Global Health describes PATH's work to control and prevent diarrheal disease, reach out to young scouts in Kenya and Uganda with HIV/AIDS information, assess the impact of malaria control efforts in Zambia, conduct DHS surveys, and shape HPV vaccine introduction in Peru.

This issue of PATH Today features a profile of PATH donor Diana Carey and her family, a report from PATH Journeys travelers to Vietnam, and brief updates on the 25th anniversary of Outlook, Forbes’ "most efficient charities" list, and more. The issue also highlights the year-end matching challenge.

The PATH Malaria Vaccine Initiative commissioned this analysis to begin elucidating the World Health Organization (WHO) process for developing policy guidelines for a malaria vaccine. The analysis considered past WHO recommendations on new interventions and assessed potential implications for a malaria vaccine.

A report on the selection and evaluation of target markers for a multiplex diagnostic platform under development. Based on the DxBox platform being developed as part of a public-private consortium lead by the University of Washington. Presented at the Molecular Medicine Tri-Conference, March 25, 2008; San Francisco, CA.

This edition of PATH Today features the article "Preventing malaria and saving lives" and includes updates on PATH's AfriComNet award for magnet theater, the PATH Journeys donor travel program, the 2007 Breakfast for Global Health, and Global Impact. The issue also includes a profile of PATH donor Erick Rabins.

PATH developed this manual for community health workers to facilitate and support the implementation of the AIDS, Population, and Health Integrated Assistance (APHIA) II project’s community-based activities in Eastern, Nyanza, and Western provinces of Kenya. The manual was developed with funding from the US Agency for International Development. It is available as one large file or as 17 smaller files.

Dr. Chilandu Mukuka, the deputy coordinator of the Zambia Ministry of Health's National Malaria Control Programme, reflects on the stresses inherent to rapidly making the range of malaria interventions available at the national level and the remarkable progress being made on malaria control in Zambia.

This poster summarizes PATH’s recent activities as part of a consortium lead by the University of Washington to develop the DxBox, a system comprising a portable instrument and low-cost disposable cards. The prototype is being developed to diagnose typhoid fever, dengue fever, rickettsial diseases, malaria, measles, and influenza. PATH’s contributions are immunoassay development, field studies, and user needs assessment. Presented at The American Society of Tropical Medicine and Hygiene (ASTMH), November 12, 2006; Atlanta, GA.

Scientists have been working for decades to develop a preventive malaria vaccine. While they have successfully demonstrated that such a vaccine is possible, many challenges continue to impede progress on the road to an effective malaria vaccine. As a result, the Malaria Vaccine Advisory Committee to the World Health Organization (WHO), coordinated by the WHO Initiative for Vaccine Research, called for a collective effort to explore and address the challenges. This effort resulted in the Malaria Vaccine Technology Roadmap process.

This is one of a series of fact sheets that describe PATH's current and past work in Kenya. The fact sheets focus on specific projects as well as unique approaches that cut across projects. This fact sheet describes PATH's work with the Eritrean government and the World Bank’s HIV/AIDS, Malaria, Sexually Transmitted Infections, and Tuberculosis Control Project (HAMSET). As part of the FHI/IMPACT project, PATH created Winning Through Caring, behavior change communication that provided information about HIV prevention, care, and support.

This special issue of Directions in Global Health features PATH's work in malaria prevention and control. It describes PATH's partnerships, experience in Zambia, clinical trial activities, efforts to prepare for vaccine introduction, and advocacy efforts.

The January 2004 issue of PATH's programmatic newsletter focuses on five projects: preventing HIV and AIDS in the Philippines, evaluating a malaria vaccine candidate, increasing youth access to services through pharmacies, advancing the Ultra Rice technology, and using theater to encourage social change.

This study evaluated the performance of PATH’s rapid diagnostic assay detecting histidine rich protein 2 (HRP-2) antigen when used by local health care providers in a rural field setting in Lao PDR and examined rapid diagnostic assays as a strategy to identify participants for in vivo treatment trials in a rural field site.