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Adherence is defined as "the extent to which a person’s behavior coincides with medical or health
advice", which is very important, for both clinical researchers and physicians, to identify the treatment
effect of a specific medication(s).

FreeDiams prescriber is the result of FreeMedForms prescriber plugins built into a standalone application. FreeDiams is a multi-platform (MacOS, Linux, FreeBSD, Windows), free and open source.

It is developed by medical doctors and is intended for use by these same professionals. It can be used alone to prescribe and / or test drug interactions within a prescription. It can be linked to any application thanks to its command line parameters. Available drugs databases : USA (FDA), Canadian (HCDPD), French (AFSSAPS), South African (SAEPI).

ADDIS is a software developed within the Dutch Escher-project for managing and analyzing clinical trial information.

ADDIS is a proof-of-concept system that allows us to simultaneously discover the possibilities of and the requirements on a database of structured clinical trials data. The automated discovery and (meta-)analysis of trial data, as well as benefit-risk assessment is supported.

OPENeP is an open source project intended to deliver a suite of medicines management apps to improve the safety and efficiency of prescribing and medicines management and demonstrate how new business models can create commercial opportunities for vendors focussed on delivering high quality service.

OSCAR (Open Source Clinical Application and Resource) from McMaster University is a web-based EMR (electronic medical record) system developed for academic primary care clinics yet suitable in specialty and non-teaching practices. It integrates with Drugref to provide Canadian pharmacopea.

This is an Open Source Practice Management System (PMS) integrated with VistA, the electronic health record and health information system originally developed by the U.S. Department of Veterans Affairs (VA).

WorldVistA EHR is an open source electronic health record (EHR) based on the highly acclaimed VistA system of the United States Department of Veterans Affairs (VA). The foundation for WorldVistA EHR was developed as part of the VistA-Office project, a collaborative effort funded by the Centers for Medicare & Medicaid Services (CMS), an agency of the Department of Health and Human Services (DHHS).

OpenRep FREE is a 100% pure Java desktop application designed to serve as a homeopathic software with capabilities to open and use multiple repertories, perform repertorizations and view its results, manage patients and view different materia medicae. It is also designed to save and load data in human readable xml format.

RPMS is an integrated solution for the management of clinical, business practice and administrative information in healthcare facilities of various sizes. Flexible hardware configurations, over 50 software applications, and appropriate network communication components combine to provide a comprehensive clinical, financial, and administrative solution. This solution is in use at most health care facilities within the Indian health care delivery system.