A 16-year-old girl was in critical condition Wednesday night after firefighters rescued her from a burning home in Hayward while her two brothers escaped with minor injuries, officials said.

The fire started around 8:25 a.m. on the corner of Mero Street and Gribben Avenue, said Alameda County Fire Department Battalion Chief Tom Pappas.

Two boys, 17 and 8, came out of a bedroom at the home and saw a fire had started in the living room, Pappas said. They managed to escape, but it appears their teenage sister may have been disoriented and wasn’t able to make it out in time, he said.

Alameda County firefighters rescued her from the house with life-threatening injuries. She was airlifted to a Santa Clara County hospital to treat burn-related injuries, and was listed in critical condition, Pappas said.

Her brothers were taken to Eden Medical Center in Castro Valley, where they were evaluated for smoke inhalation and a wellness check before they were released, he said.

Officials have yet to determine the cause of the fire, but isolated its origin to one wall in the living room, Pappas said. The one-story house sustained significant damage and has been condemned.

The children’s parents were not home at the time of the fire, Pappas said.