Cattle are a major reservoir of Shiga toxin‐producing Escherichia coli. This study investigated the occurrence of seven major STEC serogroups including O157, O145, O103, O121, O111, O45 and O26 among 578 STEC isolates ...

Nile crocodiles (Crocodylus niloticus) are important apex predators in many tropical and subtropical aquatic habitats throughout much of sub-Saharan Africa. In South Africa, large crocodile populations inhabit lakes and ...

The hearts of smaller mammals tend to operate at higher mass-specific mechanical work rates than those of larger mammals. The ultrastructural characteristics of the heart that allow for such variation in work rate still ...

Chronotherapeutic disorders such as hypertension, cardiovascular disease and asthma commonly involve the use of controlled zero-order release formulations. Ideally, the required drug should be released at predetermined ...

South Africa currently loses over 1000 white rhinoceros (Ceratotherium simum) each year to poaching incidents, and numbers of severely injured victims found alive have increased dramatically. However, little is known about ...

This study evaluated the effect of a novel formulation for starter culture associated with specific ripening conditions (NoNit™ technology) vs. a commercial» starter on the fate of selected pathogens and hygiene indicators ...

Twenty-two plant species extracted with dichloromethane and 90% methanol were investigated for their genotoxicity as well as antigenotoxicity against aflatoxin B1 induced-mutagenicity using the Ames (Salmonella typhimurium ...

A series of 2-arylbenzo[b]furan–appended 4-aminoquinazoline hybrids were prepared and evaluated for
cytotoxicity in vitro against the human lung cancer (A549), colorectal adenocarcinoma (Caco-2), hepatocellular
carcinoma ...

ETHNOPHARMACOLOGICAL RELEVANCE : Inflammation is a complex mechanism employed by the body to promote healing and restoration to normal function in the event of injury. Eleven plant species were selected in this study based ...

Rift Valley fever (RVF) is a mosquito-borne disease that affects both ruminants and humans, with epidemics occurring more frequently in recent years in Africa and the Middle East, probably as a result of climate change and ...

Staphylococcus aureus is not only a common cause of bovine mastitis, but also an agent of food poisoning in humans. In an attempt to determine whether staphylococci causing bovine mastitis could also cause food poisoning, ...

BACKGROUND : Although anthrax is endemic in Lesotho, limited information is available on the patterns of
the disease among livestock animals. This study investigated temporal patterns of anthrax
outbreaks and cases ...

The present study aimed to design and develop a nanocomposite drug delivery system
employing an antineoplastic-loaded antibody functionalized nanomicelle encapsulated within a
Chitosan–Poly(vinylpyrrolidone)–Poly(N-iso ...

Diclofenac, a non-steroidal anti-inflammatory pharmaceutical agent was responsible for the death of millions of Gyps vulture’s in the Indian sub-region with the safety of the other non-steroidal anti-inflammatory drugs ...

Housing conditions for laboratory animals can be improved by ensuring that animals are given an opportunity to perform species-specific behaviour. However, in most institutions space is a limiting factor because housing ...

Canine Staphylococcus spp. have been isolated from several clinical conditions including pyoderma, otitis, wound and post-surgical infections. Studies have shown that transmission from dogs to humans occurs, and infected ...

Peptides are important biomolecules which facilitate the understanding of complex
biological processes, which in turn could be serendipitous biological targets for future drugs. They are
classified as a unique therapeutic ...