Akovaz Precautions

Serious side effects have been reported with Akovaz including the following:

High blood pressure when given with oxytocic drugs. Serious postpartum hypertension has been described in patients who received both a vasopressor (i.e., methoxamine, phenylephrine, ephedrine) and an oxytocic (i.e., methylergonovine, ergonovine). Blood pressure should be carefully monitored when receiving both ephedrine and an oxytocic.

Tolerance with repeated administration of ephedrine. Akovaz can have a much smaller effect when given multiple times, rendering it less effective.

High blood pressure when used to prevent low blood pressure. Ephedrine has been associated with an increased incidence of low blood pressure compared with when ephedrine is used to treat low blood pressure.

Do not take Akovaz if you are allergic to Akovaz or to any of its ingredients.

Akovaz Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Akovaz, there are no specific foods that you must exclude from your diet when receiving this medication.

Akovaz and Pregnancy

Limited published data on the use of ephedrine sulfate are insufficient to determine a drug associated risk of major birth defects or miscarriage. Animal reproduction studies have not been conducted with Akovaz. Cases of potential metabolic acidosis in newborns at delivery with maternal ephedrine exposure have been reported.

Akovaz and Lactation

Limited published literature reports that ephedrine is present in human milk. However, no information is available on the effects of the drug on the breastfed infant or the effects of the drug on milk production.

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