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The Wilier Cento10NDR has both direct mount rim and flat mount disc brakes on each frame and swappable dropouts for QR and Thru-axles. Probably some steel or Ti builders would make one for you as well.

But as stated how will you get rim brake hubs to fit thru axle spacing? Or would you lace a rim brake rim to a disk hub?

You think? I think componentry makers would be reluctant to increase Q-factor on road cranks and without doing that most chainsets don't have the space to shift the chainrings 3mm outboard without the crankarm ripping the front mech off.

You think? I think componentry makers would be reluctant to increase Q-factor on road cranks and without doing that most chainsets don't have the space to shift the chainrings 3mm outboard without the crankarm ripping the front mech off.