Fatty Liver from Stribild?

Mar 1, 2013

Hello,

I was diagnosed + about three years ago, and my current labs are 478 cd4, 30.4%. I recently had a CT Scan performed due to some stomach discomfort and the results were mostly unremarkable except for "incidental fatty liver" being seen.

I had a similar CT Scan run a year ago with no notations of fatty liver.

Until this past November I had been taking a combination of Norvir, Epzicom, and Prezista for HAART. In November I switched to Stribild since it is one pill per day.

Could the Stribild cause fatty liver to develop in only a few months? My most recent labs show AST of 40 (with 40 being the high end of normal) and ALT of 67 (0-44 being normal).

I am not overweight, lift weights 6 days per week, and do cardio 4 days per week (2 miles of running or 30 minutes on an eliptical machine). I appear very fit, and my diet is relatively healthy though I can afford to eat more lowfat meals. I also am not a big drinker; I don't drink but about once or twice per month, but when I do I tend to drink 5+ drinks.

I appreciate any information/advice you can provide. I intend to follow up with my Gastro and ID doctors as well but would appreciate your opinion in addition to theirs'. Thank you.

Response from Dr. Young

Hi and thanks for posting.

There's nothing in the current literature to suggest that Stribild's medications are associated with excess risk of fatty liver, but a good starting point would be to have the radiologists actually compare side-by-side the two CT scans. This can usually be very easily accomplished.

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