ORCHARD PARK, N.Y. -- Jim Schwartz remains coy about who will start along the Detroit Lions' offensive line in next week's season opener.

But the smart money is on rookie Larry Warford at right guard and Jason Fox at right tackle.

Detroit Lions rookie Larry Warford has started the past two preseason games at right guard.Justin Rogers | MLive.com

That pairing started their second consecutive game Thursday night as the Lions throttled the Buffalo Bills 35-13 in their preseason finale. Riley Reiff (left tackle), Rob Sims (left guard) and Dominic Raiola (center) already have their spots locked up.

"It's coming into focus, as the preseason's gone on," Schwartz said of his starting offensive line. "We don't want to rush to judgment. When it's all said and done, the entire body of work is what we'll evaluate them on.

"We'll be fine at both of those positions."

Detroit is replacing Stephen Peterman at right guard and Gosder Cherilus at right tackle. It also has lost Jeff Backus at left tackle, although already has settled on Reiff to fill that void.

Warford has split first-team reps at right guard with veterans Dylan Gandy, Jake Scott and Leroy Harris, while Fox has split time with Corey Hilliard at right tackle.

But both getting a second consecutive start, knowing quarterback Matthew Stafford and the starters would have only a couple series to get in their work, is a sign Warford and Fox have taken the lead for those jobs.

Warford is a third-round draft pick out of Kentucky, while Fox is in his fourth year with Detroit.

Gandy played center on the second unit, while Scott and Harris played guard.