The blood-dyed noxious staff is made by dyeing a noxious staff with blood dye. This process is irreversible, and the dyed version is untradeable. It has the same combat bonuses, special attack, and degradation/repair mechanics as the regular noxious staff: it will degrade to a broken state after 60,000 charges of combat (but loses 2 per hit, giving a minimum time of 5 hours of combat) but can be repaired at Bob in Lumbridge, or at an armour stand.

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The Noxious staff has a special attack named Mirrorback, which requires full adrenaline and will summon a mirrorback spider to aid the player. While active, the spider will reduce damage from attacks against the player by 50%, and reflect that damage to the attacker, but the spider will also be damaged for an equal amount. For instance, if the player is hit by an attack that deals 1000 damage, both the player and the spider take 500 damage, and the attacker receives 500 points of deflection damage. This will last for ten seconds or until the spider is killed. This special attack does not deflect damage from certain attacks, and also cannot deflect damage back to attackers that are immune to deflection damage, such as the Queen Black Dragon.

Has a special attack, Miasmic Barrage, consumes 100% adrenaline and 100 charges on the staff (0.1% of maximum charge). A magic attack is launched at the opponent dealing up to 200% weapon damage, reduces their attack speed by a tick for 15 second, and halves their adrenaline gain for 15 seconds.