Research

Dr. Infante is engaged in clinical and translational research in primary immune deficiency, autoimmune and autoinflammatory diseases, and in vaccine clinical trials.

Recent and current examples include:

1. Description of a novel mutation in the interferon-gamma receptor 1 gene in a child with
disseminated mycobacterial infection.
2. Report of the experience and outcomes of state newborn screening programs for severe combined
immune deficiency syndromes (SCIDS).
3. Report of vaccine strain polio and BCG infection in an immigrant child with SCIDS
due to mutation in the RAG-1 gene.
4. Genomic analysis of response of infants and children to immunization with 23-valent pneumococcal
polysaccharide vaccine.
5. Genetic studies of a family with a novel form of periodic fever syndrome.
6. Industry sponsored clinical trial of a new formulation of
measles-mumps-rubella-varicella (MMRV) vaccine.