Our research centers around the epidemiology of healthcare
associated infections and antibiotic resistant organisms:

Healthcare-associated infections
The major focus of our research has been the epidemiology
and prevention of hospital associated infections in
high risk patient populations. Our analysis of candidemia
in a children’s hospital identified that hyperalimentation
was an independent risk factor for candidemia in children.
In a similar type of study, mucositis was identified
as the key risk factor for the development of anaerobic
bacteremia in bone marrow transplant recipients. Two
cohort studies have highlighted the prevalence of
nosocomial infections in patients undergoing high
risk procedures, such as extracorporeal membrane oxygenation
or left ventricular assist devices. We have two current
studies near completion on healthcare-associated infections
in the home setting.

Emerging antibiotic resistance
We have an interest in antibiotic resistant organisms
in community and hospital pathogens, especially antibiotic
resistant enterococci. A study of vancomycin-resistant
enterococcus colonization in patients awaiting liver
transplantation is in final stages of manuscript preparation.
In addition, we are participating in a multicenter
study to evaluate efficacy of control measures for
prevention of spread of vancomycin-resistant enterococci
and methicillin-resistant staphylococci in the ICU
setting.

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