Necrotizing fasciitis or a bacterial infection that destroys skin and soft tissues
such as fat and muscle.

Endocarditis,
which is an infection of the heart lining. Symptoms of endocarditis include
vague, flu-like symptoms, such as chronic low-grade fever and fatigue.

Meningitis, which is an infection of the fluid that
surrounds the brain and spine. Meningitis causes a severe headache with a stiff
neck, fever, nausea, and vomiting.

Septic arthritis, which is pain and inflammation of a joint caused by a
bacterial infection. Septic arthritis causes a joint to be red, hot, swollen,
and tender.

Abscesses. An abscess can form on the
skin or on tissues within the body and cause pain, swelling, and
tenderness.

Deposits of bone in soft tissues (heterotopic bone
formation). These occur especially around the hip joint and can cause pain and
problems with walking or moving the legs.

Squamous cell
skin cancer, especially if the wound lasts for several months or more or if the wound becomes a
stage 4 pressure sore. Symptoms of squamous cell cancer include growths or
patches of skin that feel scaly, bleed, or develop a crust, and sores that do
not heal.

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