IgGa-to-IgGb and IgGa-to-IgGT ratios for mean IgGa-, IgGb-, and IgGT-associated antibody to each of the R. equi Vap proteins for each horse group

Group and ratio

Value of ratio for:

VapA

VapC

VapD

VapE

VapF

VapG

VapH

IgGa/IgGb

Healthy adults

1.89 ± 0.61

1.76 ± 0.94

—a

—

1.27 ± 0.45

—

1.04 ± 0.91

Pneumonic foals

1.01 ± 1.75

0.50 ± 1.66

0.37 ± 0.85

0.53 ± 1.31

0.35 ± 0.91

0.35 ± 0.94

0.50 ± 1.24

Healthy foals

1.30 ± 0.94

1.56 ± 0.94

0.00 ± 0.00

—

0.62 ± 0.91

0.67 ± 0.94

0.47 ± 1.36

Significanceb

ac

ab

—

—

a

b

IgGa/IgGT

Healthy adults

2.57 ± 0.88

—

0.56 ± 0.77

—

3.75 ± 0.44

—

2.62 ± 0.44

Pneumonic foals

0.95 ± 1.07

1.10 ± 0.72

—

—

—

0.62 ± 0.78

—

Healthy foals

1.35 ± 0.50

5.49 ± 0.98

—

—

—

1.25 ± 0.79

4.90 ± 1.64

Significanceb

ac

b

↵a Dashes indicate an inability to calculate the ratio due to the absence of a response and hence a zero denominator.

↵b Significant differences (P ≤ 0.05 by Student's t test) between the adult and pneumonic foal group are indicated by a, those between the pneumonic and healthy foal groups are indicated by b, and those between the adult and healthy foal group are indicated by c.