Algeta ASA : Algeta to host Capital Markets Days

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11/18/2013 | 07:12am CET

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Oslo, Norway, 18 November 2013 - Algeta ASA (OSE: ALGETA), a company focused on the development of novel targeted cancer therapeutics, will host Capital Markets Days this week in Oslo, London and New York.

Presentations by Algeta's Executive Management and invited guest speakers will cover topics including alpha-pharmaceutical production, a commercial update and the current life-cycle management clinical trial plan for Xofigo® (radium Ra 223 dichloride) as well as Algeta's pipeline of Targeted Thorium Conjugates.

The event in New York will be webcast via www.algeta.com, where presentations will also be made available.

About Xofigo® (Radium Ra 223 Dichloride)

Xofigo is approved in Europe for the treatment of adults with castration-resistant prostate cancer, symptomatic bone metastases and no known visceral metastases. Xofigo is an alpha particle-emitting pharmaceutical. Its active moiety mimics calcium and selectively targets bone, specifically areas of bone metastases, by forming complexes with the bone mineral hydroxyapatite. The high linear energy transfer of alpha emitters (80 keV/micrometer) leads to a high frequency of double-strand DNA breaks in adjacent tumour cells, resulting in a potent cytotoxic effect. Additional effects on the tumour microenvironment including osteoblasts and osteoclasts also contribute to the in vivo efficacy. The alpha particle range from radium-223 is less than 100 micrometers (less than 10 cell diameters) which minimises damage to the surrounding normal tissue.

Xofigo is also approved in the US for the treatment of castration-resistant prostate cancer, symptomatic bone metastases and no known visceral disease.

In September 2009, Algeta signed an agreement with Bayer for the development and commercialization of radium-223. Under the terms of the agreement, Bayer will develop, apply for health authority approvals worldwide and commercialize Xofigo globally. Algeta is eligible for royalties and milestones based on Bayer's sales of Xofigo outside the US, and Algeta US, LLC is co-promoting Xofigo with Bayer in the US.

Algeta is a company focused on developing, manufacturing and marketing novel targeted therapies for patients with cancer. The Company is headquartered in Oslo, Norway, and has a US subsidiary, Algeta US, LLC, based in Cambridge, MA performing commercial marketing operations in the US. Algeta is listed on the Oslo Stock Exchange (Ticker: ALGETA). For more information please visit www.algeta.com.

This information is subject of the disclosure requirements pursuant to section 5-12 of the Norwegian Securities Trading Act.