Aminoethanol
RX_link

Aminoethanol
fda sheet

Aminoethanol
msds (material safety sheet)

Aminoethanol
Synthesis Reference

Aminoethanol
Molecular Weight

46.0684 g/mol

Aminoethanol
Melting Point

-114.1 oC

Aminoethanol
H2O Solubility

Miscible in water

Aminoethanol
State

Liquid

Aminoethanol
LogP

0.017

Aminoethanol
Dosage Forms

Liquid

Aminoethanol
Indication

For therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical procedures are contraindicated.

Aminoethanol
Pharmacology

Alcohol produces injury to cells by dehydration and precipitation of the cytoplasm or protoplasm. This accounts for its bacteriocidal and antifungal action. When alcohol is injected in close proximity to nerve tissues, it produces neuritis and nerve degeneration (neurolysis). Ninety to 98% of ethanol that enters the body is completely oxidized. Ethanol is also used as a cosolvent to dissolve many insoluble drugs and to serve as a mild sedative in some medicinal formulations.

Aminoethanol
Absorption

Rapidly absorbed.

Aminoethanol
side effects and Toxicity

Oral, rat LD50: 5628 mg/kg. Symptoms and effects of overdose include nausea, vomiting, CNS depression, acute respiratory failure or death and with chronic use, severe health problems, such as liver and brain damage.