We all have a chronological age — but it
doesn't have to define you. Instead, mastering your
psychological age and tweaking your thoughts and belief
patterns can reverse aging, andvastly impact the way we
experience the world, the choices we make, and the rate at
which we age — or don't. In this talk, filmed at A-Fest
Greece, celebrity hypnotherapist, Marisa Peer, explains how
you can reverse your age, and stay young in body and in mind.
Marisa is the author of one of Mindvalley's bestselling
courses, Uncompromised Life. Click here to watch the free
masterclass: http://bit.ly/2eJ1YEu

ABOUT MARISA PEER

Marisa Peer is the world's leading hypnotherapist,
bestselling author, and professional speaker. Marisa created the
Marisa Peer Method, a powerful course designed to rethink your
thought patterns and habits, and is the author of one of
Mindvalley's bestselling courses, Uncompromised Life. Through
hypnotherapy, Marisa has helped thousands of students to reframe
their thoughts and beliefs, and transform their lives in the
process.

The evidence that terahertz radiation damages biological systems
is mixed. “Some studies reported significant genetic damage
while others, although similar, showed none,” say Boian
Alexandrov at the Center for Nonlinear Studies at Los Alamos
National Laboratory in New Mexico and a few buddies. Now these
guys think they know why.

Alexandrov and co have created a model to investigate how THz
fields interact with double-stranded DNA and what they’ve found
is remarkable. They say that although the forces generated are
tiny, resonant effects allow THz waves to unzip double-stranded
DNA, creating bubbles in the double strand that could
significantly interfere with processes such as gene expression
and DNA replication. That’s a jaw dropping conclusion.

And it also explains why the evidence has been so hard to
garner. Ordinary resonant effects are not powerful enough to do
do this kind of damage but nonlinear resonances can. These
nonlinear instabilities are much less likely to form which
explains why the character of THz genotoxic effects are
probabilistic rather than deterministic, say the team.

We consider the influence of a terahertz field on the
breathing dynamics of double-stranded DNA. We model the
spontaneous formation of spatially
localized openings of a damped and driven DNA chain, and find
that linear instabilities lead to dynamic dimerization, while
true local strand separations
require a threshold amplitude mechanism. Based on our results we
argue that a specific terahertz radiation exposure may
significantly affect the natural
dynamics of DNA, and thereby influence intricate molecular
processes involved in gene expression and DNA replication.

The evidence of the TSA's fakery is now obvious thanks to the
revelations of a letter signed by five professors from the
University of California, San

Francisco and Arizona State University. You can view the full
text of the letter at:
http://www.propublica.org/documents/item/apr...

The letter reveals:

• To this day, there has been no credible scientific testing of
the TSA's naked body scanners. The claimed "safety" of the
technology by the TSA is based on rigged tests.

• The testing that did take place was done on a custom
combination of spare parts rigged by the manufacturer of the
machines (Rapidscan) and didn't even use the actual machines
installed in airports. In other words, the testing was rigged.

• The names of the researchers who conducted the radiation tests
at Rapidscan have been kept secret! This means the researchers
are not available for scientific questioning of any kind,
and there has been no opportunity to even ask whether they are
qualified to conduct such tests. (Are they even
scientists?)...

RESPONSE TO THE LETTER FROM DEPARTMENT OF HEALTH AND HUMAN
SERVICES OF OCTOBER 12, 2010 There is Still No Rigorous Hard
Data For The Safety of X-Ray Airport

Passenger Scanners The problem remains that the safety of the
X-ray airport scanners has not been independently verified.
Recently the NIST report on the
'Rapiscan Secure 1000', the most widely deployed person X-ray
scanner, and the Johns Hopkins report have been made available.
However the Johns Hopkins
report, which is the more detailed and significant because it
refers to the widely deployed Single Pose system, does not hold
to critical principles of
scientific reporting. The document is heavily redacted with red
stamps over the words and figures. In every case the electric
current used which correlates
one to one with X-ray dose has been specifically redacted. Thus
there is no way to repeat any of these measurements. While the
report purports to present the
results of objective testing, in fact the JHU APL personnel, who
are unnamed anywhere in the document either as experimenters or
as authors, were not
provided with a machine by Rapiscan. Instead they were invited
to the manufacturing site to observe a mock-up of components
(spare parts) that were said to
be similar to those that are parts of the Rapiscan system. The
tests were performed by the manufacturer using the
manufacturer's questionable test
procedures. Although the doses from Compton Backscatter
screening are potentially low, the dose rates are very high,
comparable to dose rates in CT machines.

These dose rates far exceed the limits specified for the ion
chambers that were used in both the JHU measurements and the
field measurements using the Fluke
451 reported by the TSA. There are also issues related to the
incomplete coverage of the ion chamber by the flying spot of the
backscatter machine. The data
given in the Johns Hopkins report indicate that there must be
something wrong. The very large exposures measured for scatter
radiation in the JHL report, 36%
of primary exposure above the cabinets outside the direct beam
path and 19% of primary exposure in the entrance and exit
regions, strongly suggest that the
measurement of primary exposure is too low. Scatter exposure is
usually at most a few % of the primary exposure, which is
consistent with the fact that only
a few % incident X-rays are Compton backscattered calling into
question the validity of the exposure measurement as well as the
validity of this test
equipment for a (intense) spot scanner. The report was
apparently summarized by the JHU APL; however, without
signatories, there is no accountability for the
document. Thus, important information has not been provided to
the public regarding the beam intensity under operational
conditions at airports [X-ray
photons per unit area per unit time (because it is scanning)]
and/or the related quantity - fluence (being the total energy
delivered per unit area, which is
equal to the intensity multiplied by the time the spot remains
on a given area), values that would be especially useful in
calculating the dose. Also the X-
ray tube current used in the tests or in the airport setting,
that...

...Remember, the “Resistance” is not going for impeachment,
but rather Section 4 of the 25th Amendment. That legal nicety
makes for a very neat-and-clean
surgical removal of a whack-job president, without all the
cumbrous evidentiary baggage and pain-in-ass due process
required by impeachment. All it requires
is a consensus among a very small number of high officials, who
then send a note to the leaders in both houses of congress
stating that said whack-job
president is a menace to the polity — and out he goes,
snippety-snip like a colorectal polyp, into the hazardous waste
bag of history. And you’re left with a
nice clean asshole, namely Vice President Mike Pence..."

George Orwell’s novel 1984 was incredibly popular at the
time it was published, and it remains incredibly popular to this
day. With multiple stars citing the
book as one of their favorites – including Stephen King, David
Bowie, Mel Gibson, and Kit Harrington – 1984 has been growing in
popularity in recent years.

The book reappeared on best-seller lists in early 2017, as some
argued Orwell’s dystopian vision had finally arrived.

Below are 10 facts you might not know about Orwell’s dark novel.

1. Before he wrote 1984, Orwell worked for the British
government during World War II as a propagandist at the BBC.
(Perhaps seeing the propaganda industry
up close led to his critical portrait in 1984.)

2. Orwell initially named the novel 1980, and then 1982 before
settling on 1984. Since it was written in 1948, some think that
Orwell devised the title by
inverting the year the book was written. Additionally, he
thought about naming the novel The Last Man in Europe.

3. While writing the novel, Orwell fought tuberculosis. The
disease ultimately consumed him and he died seven months after
1984 was published, with
tuberculosis as the sole cause of death.

4. In addition to fighting tuberculosis, Orwell almost died
while writing the novel. On a recreational boating trip with his
children, he went overboard.
Fortunately, neither this episode nor the tuberculosis prevented
him from finishing his novel.

5. On an ironic note, Orwell himself was under government
surveillance while writing his novel warning about government
surveillance. The British government
was watching Orwell because they believed he held socialist
opinions. This surveillance started after he published The Road
to Wigan Pier, a true story about
poverty and the lower class in England.

6. The slogan “2 + 2 = 5” originated from Russia, where the
Communist regime used it as a motto of sorts in an effort to
help them accomplish the goals of
their five-year plan in only four years. Though the slogan is
still used to point out the ills of totalitarian brainwashing
today, it was not coined by
Orwell.

7. In addition to borrowing a piece of Russian propaganda,
Orwell also borrowed some Japanese propaganda for his novel. The
“Thought Police” are based on the
Japanese wartime secret police who literally arrested Japanese
citizens for having “unpatriotic thoughts.” Their official name
was the Kempeitai, and they
officially named their pursuit the “Thought War.”

8. When Orwell worked as a propagandist for the BBC, there was a
conference room there numbered 101. This room was the room of
which he based the location
for some of his more horrifying scenes, making the scenes
themselves all the more horrifying.

9. According to Orwell’s friends and families, his second wife
Sonia Brownell was the model off of which he based the love
interest (Julia) of the book’s
main character, Winston Smith.

10. Though his book may be popular, Orwell’s novel also makes
the list of the world’s top ten most frequently banned books.
Some ban it for what they claim
are pro-communist points of view, and others have banned it
because it is anti-communist. Regardless, it is ironic that a
book warning against
totalitarianism is often an item for censorship.Just add Ultrasound & phonon
cooling... BYO BaTi :

New Solar Tech Produces
50% More Energy Than Silicon Cells

By Futurity

Researchers have created a concentrating photovoltaic (CPV)
system with embedded microtracking that is capable of producing
50 percent more energy per day
than the standard silicon solar cells...

To do this, the researchers embed tiny multi-junction solar
cells, roughly half a millimeter square, into a sheet of glass
that slides between a pair of
plastic lenslet arrays. The whole arrangement is about two
centimeters thick and tracking is done by sliding the sheet of
solar cells laterally between the
lenslet array while the panel remains fixed on the roof.

An entire day’s worth of tracking requires about one centimeter
of movement, which is practically imperceptible...

The CPV system reached 30 percent efficiency, in contrast to the
17 percent efficiency of the silicon cell. All together over the
entire day, the CPV system
produced 54 percent more energy than the silicon and could have
reached 73 percent if microcell heating from the intense
sunlight were avoided...

Prospects for concentrating photovoltaic (CPV) power are
growing as the market increasingly values high power conversion
efficiency to leverage now-dominant balance of system and
soft costs. This trend is particularly acute for rooftop
photovoltaic power, where delivering the high efficiency of
traditional CPV in the form factor of a standard rooftop
photovoltaic panel could be transformative. Here, we demonstrate
a fully automated planar microtracking CPV system <2? cm
thick that operates at fixed tilt with a microscale
triple-junction solar cell at >660× concentration ratio over
a 140° full field of view. In outdoor testing over the
course of two sunny days, the system operates automatically from
sunrise to sunset, outperforming a 17%-efficient commercial
silicon solar cell by generating >50% more energy per unit
area per day in a direct head-to-head competition. These results
support the technical feasibility of planar microtracking
CPV to deliver a step change in the efficiency of rooftop solar
panels at a commercially relevant concentration ratio.
Related Patents

The cost of depression is great -- 350 million people
worldwide suffer from this disorder and costs for traditional
SSRI treatments are high. New clinical

research results show magnesium is effective at addressing
symptoms and is safer and easier on the wallet than prescription
therapies... Emily Tarleton, MS, RD, CD, a graduate student in
Clinical and Translational Science and the bionutrition research
manager in the University of Vermont's

Clinical Research Center, and colleagues conducted a clinical
trial of over-the-counter oral magnesium tablets for
mild-to-moderate depression. Their results showed that
magnesium is safe and effective and comparable to prescription
SSRI treatments in effectiveness....

...HCFS is now being disguised under the names “fructose syrup”
or, simply, “fructose”. It is a processed chemical sweetener
that you will find in products such as bread, cakes, cookies,
condiments and soft drinks. It is cheaper to use than sugar and
extends the shelf life of products, so naturally the food
companies are inclined to use it, but at the detriment of their
customers' health.

The food companies don't want to change their money-making ways,
so they found an ingenious way to get around the food labeling
laws. HFCS is sub-categorized based on its fructose content.
Normal HFCS – HFCS 42 or HFCS 55 – contains either 42 or 55
percent fructose. The term “fructose” is now being used when
foods contain the ingredient previously called HFCS-90, which
has 90 percent fructose. Identifying HFCS-90 as “fructose” makes
it possible for them to label the product as 'not containing
HCFS' when it actually does.

CRA’s have said: “A third product, HFCS-90, is sometimes used in
natural and ‘light’ foods, where very little is needed to
provide sweetness. Syrups with 90% fructose will not state high
fructose corn syrup on the label [anymore], they will state
‘fructose’ or ‘fructose syrup’.”...What is the real danger of eating HFCS? Here are some
scientific sources to help you understand the danger of this
ingredient:

“Some people have claimed that high-fructose corn syrup is no
different than other sweeteners when it comes to weight gain and
obesity, but our results make it clear that this just isn’t
true, at least under the conditions of our tests.” “When rats
are drinking high-fructose corn syrup at levels well below those
in soda pop, they’re becoming obese — every single one, across
the board. Even when rats are fed a high-fat diet, you don’t see
this; they don’t all gain extra weight.” – Bart Hoebel,
psychology professor at Princeton University (source:
Princeton.edu)

“The study adds to a growing body of scientific literature that
indicates HFCS consumption may result in negative health
consequences distinct from and more deleterious than natural
sugar.” – Dr. Michael I. Goran (source: Huffington Post)

“Consumption of HFCS may lead to mineral imbalances, including
Zn [Zinc], Ca [Calcium] and P [Phosphorus] loss and Cu [Copper]
gain and is a potential source of inorganic mercury exposure.”–
Dufault et al. Clinical Epigenetics, 2012

“Data show that consumption of added sugars, particularly
HFCS-55, negatively impacts hippocampal function, metabolic
outcomes, and neuroinflammation when consumed in excess during
the adolescent period of development.” – Hsu et al Hippocampus,
2014.

“In the United States, food ingredient information is written
for regulators and scientists, not for the average consumer.” –
Anne Munoz-Furlong, founder of the nonprofit advocacy group Food
Allergy and Anaphylaxis Network...Please, God, bury Japan under lava and
sink it ASAP...

Fukushima’s radioactive
water to be released into ocean under new plan

The “decision has already been made” to release radioactive
material from the Fukushima plant into the ocean, according to
its owners. Fishermen have reacted with fury to the decision,
claiming it will devastate their already struggling industry.

Under the plan the radioactive material tritium, which is being
used to cool reactors whose cooling systems were damaged in the
2011 tsunami, will be released into the Pacific Ocean...

Enroll in The Rex
Research Secret College !
It's Free !

This is how Empires are birthed !
Together We can Rule the Universe !! Be an Instrument in
the Hands of God -- And You don't have to be a Religionist
!!!

Just Sign Your Computer Screen in the space below !

" I hereby solemnly pledge that at no Time will I, by spoken
Word or in Writing, by Demonstration or by Show of the Lessons
to Anyone, Give out any of the Information revealed to me in
the Rex Research Secret College "

Stevia kills Lyme disease? While it sounds too good to
be true, there is legitimate evidence suggesting a beneficial
stevia side effect could include killing Borrelia burgdorferi,
the pathogen responsible for Lyme disease. Here, we’ll dive in
to the University of New Haven study that opened our eyes to the
stevia herb’s possible Lyme-killing properties, what’s happened
since that study’s release in 2015 and if it’s too soon to
recommend stevia as a Lyme treatment in humans...
Stevia Kills Lyme Disease: Study Details

Lyme disease symptoms sometimes don’t go away with standard
two- to four-week treatment of doxycycline or amoxicillin.
University of New Haven researchers may be on to something more
plant-based, though. The team found that exposing B. burgdorferi
to stevia leaf extract wiped out Lyme disease in its different
forms...

Researchers used four types of stevia: three in liquid form
derived from standard alcohol extraction and one powdered. The
powdered stevia diluted in liquid did not show promise in
killing off Lyme, but the alcohol extracted stevia samples did.

Interestingly, a week after treatment, viable B. burgdorferi
started to surface again in the antibiotic groups. This did not
happen in the stevia group, which appeared to be a complete kill
off after seven days.

A geopolitical history of all empires, nations, kingdoms,
armies and republics. More than 500 world maps spanning all
historical events up to today. View in the high resolution. Turn
on annotations for labels, if you cannot read the key in the
upper-left corner.

...We’re now living under that condition of “intellectual
martial law.” The consequent degradation of thinking means that
the polity can’t construct a coherent consensus about what is
happening to it (or devise a plan for what to do about it). This
is exactly the point where the Overton Window turns into an
Overton Bubble, as described by Devers. The bubble comprises
ideas that are assumed to be self-evident (though they actually
aren’t) and notions that are potentially destructive of society,
even suicidally so. Here is a partial list of the current dogmas
and shibboleths inside today’s Overton Bubble:

Russia hacked the election of 2016 (no evidence required).
Russia (Vladimir Putin in particular) is bent on destroying the
USA.
All immigrants, legal or illegal, have equal status before the
law.
National borders are inconvenient, cruel, and obsolete.
Western Civilization is a malign force in human history.
Islam is “the religion of peace,” no matter how many massacres
of “infidels” are carried out in its name.
Men are a negative force in society.
White men are especially negative.
Brownie points given for behaviors under the rubric LBGTQ.
All discussion about race problems and conflicts is necessarily
racist.
The hijab (head covering worn in public by some Muslim women) is
a device of liberation for women.
There should be a law against using the wrong personal pronoun
for people who consider themselves neither men nor women
(recently passed by the Canadian parliament).
A unifying common culture is unnecessary in national life
(anything goes).
Colonizing Mars is a great solution to problems on Earth.

That list defines the general preoccupations of the thinking
classes today — to the exclusion of other issues. Here is an
alternative list of matters they are not generally concerned
about or interested in:

The energy quandary at the heart of our economic malaise... The
enormous debt racked up to run society in the absence of
affordable energy inputs... The dangerous interventions and
manipulation in markets by unelected officials of the Federal
Reserve... The extraordinary dysfunction of manipulated
financial markets... The fragility of a banking system based on
accounting fraud... The dysfunction and fragility of the
American suburban living arrangement... The consequences of a
catastrophic breakdown in the economy due to the above...
The destruction of planetary ecology, threatening the
continuation of the human race, and potentially all life.

Now, the question of motive. Why does the thinking class in
America embrace ideas that are not necessarily, and surely not
self-evidently, truthful, and even self-destructive? Because
this class is dangerously insecure and perversely needs to
insist on being right about its guiding dogmas and shibboleths
at all costs. That is why so much of the behavior emanating from
the thinking class amounts to virtue signaling — we are the good
people on the side of what’s right, really we are! Of course,
virtue signaling is just the new term for self-righteousness.
There is also the issue of careerism. So many individuals are
making a living at trafficking in, supporting, or executing
policy based on these dogmas and shibboleths that they don’t
dare depart from the Overton Bubble of permissible, received
thought lest they sacrifice their status and incomes.

The thinking classes are also the leaders and foot-soldiers in
American institutions. When they are unable or unwilling to
think clearly, then you get a breakdown of authority, which
leads to a breakdown of legitimacy. That’s exactly where we’re
at today in our national politics — our ability to manage the
polity.

MO’s Just Got a Lot More
Frightening with Approval of New Monsanto Product

by Christina Sarich

Forget spraying pesticides on your food, now they’ll be
genetically engineered to be in your food, thanks to Monsanto’s
latest quiet approval via the US Environmental Protection
Agency.

The EPA just told Monsanto they could go ahead and bypass
spraying our crops with carcinogenic chemicals like Round Up and
just go ahead and breed them right into the crops themselves.
Using a process called RNA interference, Monsanto’s RNAi plant
will supposedly kill pesky rootworms when they come along to
chomp on them- but what else will these genetically modified
crops do to beneficial bugs, the soil, and human health? The EPA
has no idea, because they haven’t done a single trial on
RNAi-altered crops...

Without much more than a whisper from the mainstream media,
Monsanto’s newest Frankenfood has received full EPA approval and
will be arriving on dinner plates by the end of the decade. The
implications of this are harrowing, to say the least.... http://www.openculture.com

Distilled Water Kills
Bladder Cancer Cells As Effectively As Chemotherapy

Can distilled water kill bladder cancer cells? That’s the
question doctors at the Department of Urology, University of
Bonn, Germany are attempting to answer. The surprising results
suggest simple distilled water might just be a bladder cancer
cell’s worst nightmare.

Reporting in the October 2006 International Journal of Clinical
Practice, the team said that the surgical procedure called
transurethral resection is used to remove bladder cancer and
followed by instillation of chemotherapeutic agents such as
mitomycin; it is considered as standard therapy in recurrent
superficial bladder cancer.

“However, incidence of bladder cancer is increasing and
contrariwise, the resources to finance health care systems are
decreasing. Therefore, effective alternatives to expensive
chemotherapeutics are necessary,” said the authors.

Recurrence of bladder cancer after transurethral resection is
caused by reimplantation of dissolved tumor cells. To kill them
off, mitomycin is used. The researchers took human bladder
cancer cells and incubated them in mitomycin or distilled water.

“Distilled water led to significant cytolysis in all tumor
cells,” they write. “This effect was comparable to exposition to
mitomycin. Distilled water and mitomycin have comparable in
vitro effects in bladder cancer cells,” the scientists wrote.

This was not the first study to determine distilled water kills
bladder cancer cells. In a 1986 issue of European Urology, the
effect of distilled water on tumor cells was compared to the
effect of chemotherapeutic agents dissolved in saline and in
distilled water.

“Distilled water proved as effective as chemotherapeutic agents
in distilled water and more destructive than chemotherapeutic
agents in saline within the 2-hour time limit of the
experiment,” the researchers reported.

Maybe some of those that have repeated this shallow and foolish
assertion will think twice before regurgitating it again after
understanding another viewpoint. If that is even possible
for a mind that is this corrupted to espouse or promote
something so asinine showing the least bit of respect to the
other being spoken to. This information is not meant to
criticize or offend anyone, yet must be written. Might we
all come to a deeper level of understanding as to what many are
actually reinforcing through ignorance and engaging in with such
an unnecessary, taught habit...UPDATED 10 JULY

Disposable! One time use only! Holds 100 gallons of fresh
drinking water. Keeps water fresh for up to 12 weeks. Attaches
to faucet, fills in minutes and includes pump to dispense water.
Made of FDA approved food grade materials and is BPA-Free.Worthless gonzo POS corporate fag-macho
punks for hire :

Israeli Officer Shot Dead
During Training Exercise While Pretending to be a
Palestinian

An Israeli Army officer was accidentally shot and killed by one
of his own troops during a training operation in which he was
pretending to be a Palestinian at an Israeli military checkpoint
in the occupied West Bank on Tuesday.

The 22 year old army commander David Golovenchik was carrying
out a training exercise with his soldiers, but hadn’t told the
soldiers to unload their weapons prior to the drill...

Mucus-free Life LLC is a health and wellness organization
dedicated to educating the world about the Mucusless Diet
Healing System, the natural healing methods of Prof. Arnold
Ehret, and the benefits of a mucus-free lifestyle.

No time to get fit? Think
again — Just one minute of intense exercise produces
health benefits.

Researchers at McMaster University have found that a single
minute of very intense exercise produces health benefits similar
to longer, traditional endurance training.

The findings put to rest the common excuse for not getting in
shape: there is not enough time.

"This is a very time-efficient workout strategy," says Martin
Gibala, a professor of kinesiology at McMaster and lead author
on the study. "Brief bursts of intense exercise are remarkably
effective."

Scientists set out to determine how sprint interval training
(SIT) compared to moderate-intensity continuous training (MICT),
as recommended in public health guidelines. They examined key
health indicators including cardiorespiratory fitness and
insulin sensitivity, a measure of how the body regulates blood
sugar.

A total of 27 sedentary men were recruited and assigned to
perform three weekly sessions of either intense or moderate
training for 12 weeks, or to a control group that did not
exercise).

The McMaster team has previously shown that the SIT protocol,
which involved three 20-second 'all-out' cycle sprints, was
effective for boosting fitness. The workout totaled just 10
minutes, including a 2-minute warm-up and 3-minute cool down,
and two minutes of easy cycling for recovery between the hard
sprints.

The new study compared the SIT protocol with a group who
performed 45 minutes of continuous cycling at a moderate pace,
plus the same warm-up and cool down. After 12 weeks of training,
the results were remarkably similar, even though the MICT
protocol involved five times as much exercise and a five-fold
greater time commitment.

"Most people cite 'lack of time' as the main reason for not
being active", according to Gibala. "Our study shows that an
interval-based approach can be more efficient—you can get health
and fitness benefits comparable to the traditional approach, in
less time."

Gibala, who has studied has been studying interval training for
more than a decade. O, was the first researcher to show that a
few minutes per week of intense exercise produced benefits
similar to longer, continouous workouts. Over time, his team has
experimented with different protocols in an effort to identify
the most time-efficient exercise strategies.

"The basic principles apply to many forms of exercise," he says.
"Climbing a few flights of stairs on your lunch hour can provide
a quick and effective workout. The health benefits are
significant."

PROSTATE health can be a pretty awkward subject, so prepare to
blush at this new research from Harvard University.

Scientists say frequent ejaculations could be the key to keeping
the semen-producing gland healthy and avoiding cancer.

In fact, in a study of almost 32,000 men published in the
journal of European Urology, researchers found high levels of
sexual activity can reduce the risk of contracting prostate
cancer by 33 per cent.

The optimum number is 21 ejaculations per month.

We’ve done a few quick calculations and that’s equal to 252
times annually — or almost 70 per cent of days in a year.

Experts aren’t exactly sure why ejaculation lowers the risk of
prostate cancer, but they speculate it might help flush out
cancer-causing toxins.

According to statistics from the University of Sydney, prostate
cancer is the most common cancer diagnosed in Australia, and the
third most common cause of cancer death.

It’s more common in older men, with 85 per cent of cases
diagnosed in those over 65 years of age, so the results of this
study are definitely worth taking on board.

Enjoyable as it may be, frequent ejaculation isn’t a magical
one-stop shop.

The Harvard researchers pointed out an active sex life may be an
indicator of good general health, which in itself is likely to
lower the risk of cancer.

Therefore, it’s also important to maintain a good diet and
exercise routine, and get regular check-ups from your doctor.

Shane Bales, The Ruiner, and Randy Maugans cover the
continued development of the media creation that is the Blue
Avians-Secret Space Program entertainment franchise. Post-Avalon
, the forum wars, the entrance of David Wilcock as he looks for
his next vein of material, Gaia(m) TV, and the mechanics of
intelligence operations that run through the so-called
"alternative media" communities.

Kai Murros, Finland's pan-European nationalist and
intellectual, narrates what must become the new philosophy for
all Europeans around the globe. It is a call to arms. Will you
die for your family, your people?

Plasma thruster
breakthrough as researchers discover how to control
magnetic fields in the radical engines

New experiments shed light on environmental
factors that influence plasma flowStudy identified transition that could
allow plasma flow to guide magnetic field This occurs while thrust is maintained, and
at slower velocity than expected

By Cheyenne Macdonald

New experiments to uncover the factors that influence plasma
flow could bring scientists closer to achieving an
electrodeless plasma thruster.

In space, it’s known that magnetic field lines become
stretched by plasma flows, causing them to increase – but in
the lab, scientists have found that the opposite occurs,
causing the magnetic field to decrease.

Based on these interactions, researchers are working to create
thrusters that use an expanding magnetic field, in which
plasma is accelerated to propel a spacecraft.

Scientists have now identified the transition point that could
allow plasma flow to guide the magnetic field toward space
while still maintaining thrust, in what could help overcome
one of the technology’s biggest challenges.

Researchers are working to create thrusters that use an
expanding magnetic field, in which plasma is accelerated to
propel a spacecraft...

Thomas Jefferson ( 1816 ): “To preserve their
independence, we must not let our rulers load us with
perpetual debt… If we run into such debts, as that we must be
taxed in our meat and in our drink, in our necessaries and our
comforts, in our labors and our amusements, for our callings
and our creeds – as the people of England are – our people,
like them, must come to labor sixteen hours [per day], give
the earnings of fifteen of these to the government for their
debts and daily expenses; and the sixteenth being insufficient
to afford us bread, we must live, as they now do, on oatmeal
and potatoes – have no time to think, no means of calling the
mismanagers to account – but be glad to obtain subsistence by
hiring ourselves to rivet [the managers’] chains on the necks
of our fellow-sufferers.”

Researchers found that a compound found in broccoli sprouts
and other cruciferous vegetables led to a significant
improvement in fasting blood glucose levels among obese adults
with type 2 diabetes.

Furthermore, the compound, which is called sulforaphane, was
found to reduce the amount of glucose produced by cultured
liver cells, and it also appeared to reverse abnormal gene
expression in the livers of rats.

Sulforaphane reduces
hepatic glucose production and improves glucose control in
patients with type 2 diabetes

Annika S. Axelsson, et al.

Abstract

A potentially useful approach for drug discovery is to connect
gene expression profiles of disease-affected tissues (“disease
signatures”) to drug signatures, but it remains to be shown
whether it can be used to identify clinically relevant
treatment options. We analyzed coexpression networks and
genetic data to identify a disease signature for type 2
diabetes in liver tissue. By interrogating a library of 3800
drug signatures, we identified sulforaphane as a compound that
may reverse the disease signature. Sulforaphane suppressed
glucose production from hepatic cells by nuclear translocation
of nuclear factor erythroid 2–related factor 2 (NRF2) and
decreased expression of key enzymes in gluconeogenesis.
Moreover, sulforaphane reversed the disease signature in the
livers from diabetic animals and attenuated exaggerated
glucose production and glucose intolerance by a magnitude
similar to that of metformin. Finally, sulforaphane, provided
as concentrated broccoli sprout extract, reduced fasting blood
glucose and glycated hemoglobin (HbA1c) in obese patients with
dysregulated type 2 diabetes.

This is the full video of Paul Beckwith's review of a recent
USGS report that compiled research on Arctic methane. His
videos are only allowed to be 15 minutes long so I combined
them to make one uninterrupted video.

California lists
Glyphosate, an herbicide and the active ingredient in
Monsanto‘s popular weed killer Roundup, as a “cancer
causing” chemical.

By Aaron Kesel

Glyphosate will be added to California’s Proposition 65 list
of chemicals known to cause cancer effective July 7, the
state’s Office of Environmental Health Hazard Assessment
(OEHHA) said. Monsanto argues that the decision is
“unwarranted on the basis of science and the law.”...

...After each Islamic terrorist attack or migrant crime spree,
the left predictably virtue signals, informing us that we must
combat our own slaughter with love, tolerance, and open
borders. Of course, this only leads to the Islamization of
nations as the dead cry out from their graves that at least
they were morally superior to their murderers. Still, it takes
liberals falling on their own sword to realize that their
theories don’t work when put into action, and even then, many
refuse to acknowledge that the flaw is in their agenda and not
its execution.

Syrian hairstylist Mohammad Hussain Rashwani was hailed by
local media as a “model for integration of asylum seekers”
after migrating from Damascus to Germany during the refugee
crisis. Falling for this leftist propaganda, 64-year-old

Ilona F. took Mohammad under her wing by offering him a
position at her salon in Herzberg in September 2016. Sadly, it
took Ilona just 5 months to discover the truth about just how
dangerous even vetted asylum seekers can be.

German online newspaper Lausitzzer Rundschau reports that the
left’s poster child for Muslim migration, 39-year-old
Mohammad, brutally attacked his elderly female boss on June
28, stabbing her in the neck as Muslim jihadists often do.

The Syrian refugee, who was lauded by liberals as proof of
Islamic “integration,” carried out the Quran’s command to
“smite at their necks,” nearly killing his employer.

Ilona managed to escape certain death when another 22-year-old
Syrian intervened and stopped Mohammad, which authorities say
likely saved the woman. She was forced to undergo emergency
surgery but is now in stable condition...

Aside from the Quran’s dozens of other violent commands
towards unbelievers, verses 47:4 and 8:12 specifically order
the stabbing of non-Muslims at their necks. This can mean
either beheading, stabbing, or simple throat-slitting —
whatever accomplishes “inflicting slaughter upon them” and
“casting terror into the hearts of those who disbelieve.”

Surprisingly, the only interpretation of this that’s false is
any inclination that Muslims should be peaceable to
non-Muslims.

New data from Sweden
shows how immigration and refugees from Islamic countries
puts especially women in danger.

92 percent of all severe rapes (violent rapes) are committed
by migrants and refugees. 100 percent of all attack rapes
(where victim and attacker had no previous contact) are
committed by that same group. In other words, thousands of
Swedish women would not have been raped and thereby
traumatized for life, had it not been for the influx from
Islamic countries.

The top-10 list over rapists’ national back ground shows only
one non-Islamic country (Chile). Most rapists have Iraqi back
ground, followed by refugees and migrants from Afghanistan,
Somalia, Eritrea, Syria, Gambia, Iran, Palestine, Chile and
Kosovo.

When taking into account the number of people from the
different nationalities in Sweden, Afghans are 79 times more
likely to commit a sexual crime than people born from Swedish
citizens.

For many years, whenever one Googled “jihad,” Jihad Watch was
the first result. This was back in the days when Google’s
results were based on the relevance of the subject matter to
the search and the popularity of the site. But then Google
began engaging in social engineering, attempting to manipulate
opinion by changing the results of searches to lead people to
sites that offered the perspectives it favored. Then when one
searched for “jihad,” Jihad Watch became the
second result, and then the fourth, even though our readership
was steadily rising; replacing it at the top were Islamic
apologetics sites with a fraction of the readership, offering
soothing falsehoods about the meaning of jihad...

"I recently found this interview in my archives. I was
shooting a documentary called “The Information Society” in
1979 and filmed this in Cedar Rapids Iowa. Compushop had just
begun selling the Apple II and this guy had a keen sense of
what was coming."

Brain Drain: The Mere
Presence of One’s Own Smartphone Reduces Available
Cognitive Capacity

Adrian F. Ward, et al.

Abstract

Our smartphones enable—and encourage—constant connection to
information, entertainment, and each other. They put the world
at our fingertips, and rarely leave our sides. Although these
devices have immense potential to improve welfare, their
persistent presence may come at a cognitive cost. In this
research, we test the “brain drain” hypothesis that the mere
presence of one’s own smartphone may occupy limited-capacity
cognitive resources, thereby leaving fewer resources available
for other tasks and undercutting cognitive performance.
Results from two experiments indicate that even when people
are successful at maintaining sustained attention—as when
avoiding the temptation to check their phones—the mere
presence of these devices reduces available cognitive
capacity. Moreover, these cognitive costs are highest for
those highest in smartphone dependence. We conclude by
discussing the practical implications of this
smartphone-induced brain drain for consumer decision-making
and consumer welfare...

...Smartphone owners interact with their phones an average of
85 times a day, including immediately upon waking up, just
before going to sleep, and even in the middle of the night
(Perlow 2012; Andrews et al. 2015; dscout 2016). Ninety-one
percent report that they never leave home without their phones
(Deutsche Telekom 2012), and 46% say that they couldn’t live
without them (Pew Research Center 2015)...

1. You are the entrepreneur of your life --- He studied
20th-century philosophy as an undergraduate at Stanford
University.
2. Do one thing uniquely well --- An avowed libertarian, he founded The
Stanford Review in 1987.
3. Make sure people align properly --- He formed friendships with other
students at Stanford, many of whom contributed to the Stanford
Review. Some of these friends later took up jobs at PayPal and
became part of the PayPal Mafia.
4. Aim for monopoly ---
In 1998 Thiel co-founded PayPal. It went public on
February 15, 2002, and was sold to eBay for $1.5 billion later
that year.
5. Don't be a fake entrepreneur --- He was the first outside investor in
Facebook, with a 10.2% stake acquired in 2004 for $500,000.
6. Value substance over status --- In addition to Facebook, Thiel has
made early-stage investments in numerous startups, including
Booktrack, Linkedln, Friendster, Yammer, Yelp, Palantir
Technologies, Big think.
7. Don't lose sight of what's valuable --- In February 2013, Thiel received a
TechCrunch Crunchie Award for Venture Capitalist of the year.
8. Trends are overrated
--- He was a US-rated Chess Master and one of the
highest ranked under-21 players in the country.
9. Don't dwell on the past --- He's a managing partner in Founders
Fund, a venture capital fund with $2 billion in assets under
management.
10. Find the secret path
--- In 2010 he created the Thiel Fellowship, which
will award $100,000 to 20 people under 20 years old, to spur
them to drop out of college and create their own ventures.

Chinese scientists claim to have made a major breakthrough in
magnetic detection technology that could bring unprecedented
accuracy to the process of finding hidden metallic objects –
from minerals to submarines.

The Chinese Academy of Sciences, the country’s largest
research institute, said in an article on its website on
Wednesday that a “superconductive magnetic anomaly detection
array” has been developed in Shanghai and passed inspection by
an expert panel.

The experts were quoted as saying that the device, which works
from the air, could be used to pinpoint the location of
minerals buried deep beneath the earth in Inner Mongolia, for
example, with a level of precision as high as anything
currently available around the world.

The device could also be used on civilian and military
aircraft as a “high performance equipment and technical
solution to resources mapping, civil engineering, archaeology
and national defence”, the article said.

China’s military may soon adopt the technology, if it hasn’t
already, said Professor Zhang Zhi, an expert in remote sensing
with the Institute of Geophysics and Geomatics, China
University of Geosciences in Wuhan, Hubei.

“The technology could be used to detect minerals on land, and
in the ocean to nail down submarines,” said Zhang, who was not
involved in the project.

Anti-submarine aircraft have been equipped with magnetic
anomaly detectors, or MAD, since World War II. The devices
monitor the small disturbances metallic objects cause to the
Earth’s magnetic field, analyse the data and use complex
algorithms to calculate the object’s position.

Precise locations are often difficult to obtain, however,
because the strength of a magnetic signal drops rapidly as the
distance from the source increases.

Aircraft have to fly low, and the submarine has to be
operating sufficiently close to surface for the device to
register it. The power of the signal can be reduced by other
factors, too, such as if the submarine is made from less
ferromagnetic materials.

The experts were quoted as saying that the device, which works
from the air, could be used to pinpoint the location of
minerals buried deep beneath the earth in Inner Mongolia, for
example, with a level of precision as high as anything
currently available around the world.

The device could also be used on civilian and military
aircraft as a “high performance equipment and technical
solution to resources mapping, civil engineering, archaeology
and national defence”, the article said.

China’s military may soon adopt the technology, if it hasn’t
already, said Professor Zhang Zhi, an expert in remote sensing
with the Institute of Geophysics and Geomatics, China
University of Geosciences in Wuhan, Hubei.

“The technology could be used to detect minerals on land, and
in the ocean to nail down submarines,” said Zhang, who was not
involved in the project.

Anti-submarine aircraft have been equipped with magnetic
anomaly detectors, or MAD, since World War II. The devices
monitor the small disturbances metallic objects cause to the
Earth’s magnetic field, analyse the data and use complex
algorithms to calculate the object’s position.

Precise locations are often difficult to obtain, however,
because the strength of a magnetic signal drops rapidly as the
distance from the source increases.

Aircraft have to fly low, and the submarine has to be
operating sufficiently close to surface for the device to
register it. The power of the signal can be reduced by other
factors, too, such as if the submarine is made from less
ferromagnetic materials.

Dr Lei Chong, an assistant researcher studying MAD technology
at the Department of Micro/Nano Electronics, Shanghai Jiaotong
University, said the Chinese device was different from
conventional designs in at least two ways.

The first is the large number of probes the device uses. With
this “array”, it can collect much more data than traditional
detectors, which tend to use just one antenna, said Lei, who
was not involved in the project.

The new MAD also uses a superconductive computer chip cooled
by liquid nitrogen. This super-cool environment significantly
increases the device’s sensitivity to signals that would be
too faint for traditional devices to spot.

“I am surprised they made such an announcement,” Lei said.
“Usually this kind of information is not revealed to the
public because of its military value.”

The superconductive MAD array was developed over four years by
a research team led by Professor Xie Xiaoming from the
Shanghai Institute of Microsystem and Information Technology,
according to the CAS article.

Xie could not immediately be reached for comment.

Chinese research teams have also recently completed the
development of eight other types of magnetic detectors, some
of which are small and sensitive enough to be used on
satellites, the article said.

The academy said that due to the difficulties involved in
developing such equipment, most countries, including the
United States, don’t yet have it. Germany is the rare
exception, it said.

Despite the article’s claims, Lei said it was too early to say
whether China was leading the world in MAD technology.

“The US military might have developed similar equipment but
kept their lips sealed about it,” he said.

“It’s impossible, therefore, to compare one country to another
on this kind of sensitive technology based only on openly
available information.

“Converting a mineral detector to a MAD for submarines
requires a lot of extra work. Military users have very
different requirements to those in the civilian sector,” he
said.

An ultrahigh resolution magnetic resonance imaging method and
apparatus, the method comprises the following steps of:
placing a test sample within an action range of a magnetic
gradient source and a nano-scale superconducting quantum
interference device, applying a static magnetic field on the
test sample by a static magnetic source, and applying a
nuclear magnetic resonance radio-frequency pulse on the test
sample by a radio-frequency source to excite the test sample
to cause nuclear magnetic resonance; directly coupling the
nano-scale superconducting quantum interference device with
the test sample to detect nuclear magnetic resonance spectrum
signals generated by the test sample; establishing an image of
the test sample according to the detected nuclear magnetic
resonance spectrum signals and space distribution information
of gradient magnetic fields generated by the magnetic gradient
source.

Clif High is the programmer and owner of the Webbot, a future
viewing radical linguistics database and algorithm that
predict future trends based on the emotional content of
language on the internet. He joins us for a rousing two hours
of cutting edge discussion.Website: https://www.halfpasthuman.com/

Hour 1: Language and temoral displaement ... Buckminster Fuller and N. A. Kozyrev ... The correlation between
now and the 1930s. an energy trough that we have lived through
all of our lives, and the new energetics that will build up
and run for the next 100 years. ... Social engineering from the 1830s,
the utopians and various early technology pioneers: a wave
precursor of the late 20th-early 21st century; the boundary
mirror on both sides of the boundary; CERN and time
manipulation; the wider human development of cognitive
abilities that could preclude social engineering and controls.... Temporal awareness in
the 1930s era, later disappears in the 1960s; we now are going
back into that era of heightened temporal awareness; and the
ability to alter time and temporal awareness.... Space energies
heightened; top of the earth ripped off---reduced oxygen
levels on the earth....
Crypto currencies, block chain: how it works, security;
the good and bad; speculation vs. value.... Fed contractors on the dark web;
champions of crypto due to need to conceal transactions... A monetary store (hard
assets/precious metals) vs. a true currency; the VALUE of
Bitcoin is in the code and it's ability to tranmit value
securely and with trusted accounting; the HASH
encryption/decryption schema; the speculation aspects: an
emotional response....
The stability of crypto, the internet, and the power
grid; vulnerabilities and strengths.... The war of the gods and the "Changer";
arrival of the Sky People. the wars between Sky People and
Star People. How these wars are programmed into our collective
psyche, even our DNA; Fight, Flight, Freeze as instinctive
responses to threat....
Planetary influences on climate and human behavior.... The early beginnings of
the webbot: SUN DISEASE...and now the foreshadowing of the
coming ice age...blue plasma energy, huge build-ups of energy
in the ionosphere...huge lightening blasts carving the Grand
Canyon... David DuByne of Adapt2030 on YouTube...Walter
Thornhill, David Talbot "Thunderbolt of the Gods".... DNA is NOT what we
think: Epigenetics as a key to self-transformation on the
mental and cellular levels; connections to Tao and Chi energy
with epigenetics. "Most humans never change..." (Krishnamurti)... Stillness, collapse, and
Kozyrev's work; consciousness and the ability to find answers;
tent revivals of the 1930s, the 1960s revivals; now the
open-air mystical experiences; psychedelics/entheogens; New
Age, and ....

Hour 2: The yogi and the Bluebirds: the quest for something
bigger...enter the Orb Beings...Corey Goode, David Wilcock;
Google search on Corey Goode, Blue Avians...etc. contains NO
negative information; Clif reveals the gaming the Google
search engine (SEO) using templates, key word searches, byte
codes...a deep "official" operation of skewing web searches.
... Hard researchers vs. soft disclosure"...how legitimate
researchers with evidence are marginalized, i.e. Sean
Gautreaux, WHO/WHAT IS IN OUR SKIES... Corey Goode/Blue Avians
as a social engineering project.... Who is Constantine? The creation of a
monolithic narrative/quasi-religious structure: Blue Avians.... The contamination of the
emotional language in the webbot by Goode/Wilcock/Weidner
utilizing the reports' Antarctica material. Promulgating
emotional reactions; cult-like usage of semiotics, imagery,
and language.... Issues
with David Wilcock... Incarnational
issues with sociopathy/psychopathy.... Jimmy Church and the "infltration" of
UFOlogy; the language behind of Contact In The Desert as a
tent meeting; the language co-opted; how a cult points fingers
outside itself to own the narrative.... Clif's detection of stolen narratives
in the model space of the webbot; the contamination of the
data was being redeployed by the Corey Goode camp. How Clif
trapped the Gaia(m) effect in the data.... The importance of Antarctica... Spirituality in UFOlogy... The myths and mind
control of "ascension"....
Bill Ryan as Puppetmaster, Jimmy Church as the Enforcer
of "order" in the Space Goat Farts sectors.... Colonel Marrs: The War
Through Time, hunters and collectors of past life artifacts;
how we have an image/visage through incarnational cycles.
Augmenting life cycles with time manipulation via CERN.... Corey Goode could wind
up the "sacrificial lamb"?; the death culture behind
"super-soldier" media figures. The Baphomet image, Ramsaur
(the Goat God). Strange fire inside the Corey goode camp.

Ever get a call from these annoying pricks? This should feed
your appetite for revenge! We flood the scammers lines to
prevent them from being able to scam any other people, AND we
recorded it for your listening pleasure!

A new study demonstrates a way to adapt the so-called Trombe
wall -- a passive solar building design from the 19th century
-- to not only heat but also cool buildings, while drastically
reduce associated carbon emissions. The new design is now
being tested by locals in Saint Catherine, Egypt.

Researcher Marwa Dabaieh from Lund University in Sweden has
come up with a way to adapt the so-called Trombe wall -- a
passive solar building design from the 19th century -- to not
only heat but also cool buildings, while drastically reduce
associated carbon emissions. The new design is now being
tested by locals in Saint Catherine, Egypt.

"In Egypt, fossil fuels account for 94% of all energy. There
is therefore a great need for innovative energy solutions to
reduce carbon emissions that can also be used in rural
communities which do not always have electricity," says
architectural researcher Marwa Dabaieh who divides her time
between Lund University and the British University in Egypt.

The vented Trombe wall is an old, yet still popular passive
construction technique that hardly requires any energy. Marwa
Dabaieh has continued to develop this technique so that it can
be used for not only building heating, but also cooling --
providing a comfortable indoor temperature all year around.

"The new design uses renewable wind and solar energy to
generate cooling and heating in buildings. The adjustments
have also eliminated the original Trombe wall problem with
overheating, which in turn has drastically reduced the total
energy consumption and carbon emissions," says Marwa Dabaieh.

The new design has taken the aesthetic aspects of the Trombe
wall into account, so that it can be integrated into modern
buildings and become an attractive architectural element. The
materials used to build the wall are local stone, wood and
wool, as well as locally produced glass.

"Locals have been involved in every step of the process, so
that they can easily build the Trombe wall themselves or show
others how to construct one. Local construction could also
help create new opportunities for young and unemployed
people," says Marwa Dabaieh.

The villagers in Saint Catherine who have installed the Trombe
wall have experienced a nicer indoor temperature, and several
people have expressed a desire to have the new ventilation
system installed; something Marwa Dabaieh sees as positive
sign.

This passive ventilation system could be key for a sustainable
future.

"In order to overcome future environmental challenges, we must
invest in passive, low-cost systems that require almost no
energy from fossil fuels. The vented Trombe wall has a great
potential for meeting the steadily increasing energy demands
without increasing carbon emissions," says Marwa Dabaieh.

Adapted Trombe wall now
used for both heating and cooling buildings using
renewable energy sources

In Egypt, fossil fuels account for 94% of all energy. There is
a need for innovative energy solutions to reduce carbon
emissions that can also be used in rural communities which do
not always have electricity. Researcher Marwa Dabaieh from
Lund University in Sweden has come up with a way to adapt the
so-called Trombe wall – a passive solar building design from
the 19th century – to not only heat but also cool buildings,
while drastically reduce associated carbon emissions. The new
design is now being tested by locals in Saint Catherine,
Egypt. Learn how the Trombe wall design works:

...Independent researcher Christine Johnson documented this
fact. Her classic investigation has been reprinted at
aliveandwell.org. Here is just a partial list of factors that
will cause an HIV antibody test to read positive for reasons
that have nothing to do with HIV:

CNN producer John Bonifield admits the networks Trump/Russia
coverage is "bullsh*t" and a "witch hunt" just for the
ratings." Project Veritas got him on take making those and
other stunning revelations.

Some biodegradable plastics could in the future be made using
sugar and carbon dioxide, replacing unsustainable plastics
made from crude oil, following research by scientists from the
Centre for Sustainable Chemical Technologies (CSCT) at the
University of Bath.

Polycarbonate is used to make drinks bottles, lenses for
glasses and in scratch-resistant coatings for phones, CDs and
DVDs... Current manufacture processes for polycarbonate use
BPA (banned from use in baby bottles) and highly toxic
phosgene, used as a chemical weapon in World War One... Bath
scientists have made alternative polycarbonates from sugars
and carbon dioxide in a new process that also uses low
pressures and room temperature, making it cheaper and safer to
produce... This new type of polycarbonate can be biodegraded
back into carbon dioxide and sugar using enzymes from soil
bacteria... This new plastic is bio-compatible so could in the
future be used for medical implants or as scaffolds for
growing replacement organs for transplant

Polycarbonates from sugars offer a more sustainable
alternative to traditional polycarbonate from BPA, however the
process uses a highly toxic chemical called phosgene. Now
scientists at Bath have developed a much safer, even more
sustainable alternative which adds carbon dioxide to the sugar
at low pressures and at room temperature.

The resulting plastic has similar physical properties to those
derived from petrochemicals, being strong, transparent and
scratch-resistant. The crucial difference is that they can be
degraded back into carbon dioxide and sugar using the enzymes
found in soil bacteria.

The new BPA-free plastic could potentially replace current
polycarbonates in items such as baby bottles and food
containers, and since the plastic is bio-compatible, it could
also be used for medical implants or as scaffolds for growing
tissues or organs for transplant.

Dr Antoine Buchard, Whorrod Research Fellow in the
University's Department of Chemistry, said: "With an
ever-growing population, there is an increasing demand for
plastics. This new plastic is a renewable alternative to
fossil-fuel based polymers, potentially inexpensive, and,
because it is biodegradable, will not contribute to growing
ocean and landfill waste.

"Our process uses carbon dioxide instead of the highly toxic
chemical phosgene, and produces a plastic that is free from
BPA, so not only is the plastic safer, but the manufacture
process is cleaner too."

Dr Buchard and his team at the Centre for Sustainable Chemical
Technologies, published their work in a series of articles in
the journals Polymer Chemistry and Macromolecules.

In particular, they used nature as inspiration for the
process, using the sugar found in DNA called thymidine as a
building block to make a novel polycarbonate plastic with a
lot of potential.

PhD student and first author of the articles, Georgina
Gregory, explained: "Thymidine is one of the units that makes
up DNA. Because it is already present in the body, it means
this plastic will be bio-compatible and can be used safely for
tissue engineering applications.

"The properties of this new plastic can be fine-tuned by
tweaking the chemical structure -- for example we can make the
plastic positively charged so that cells can stick to it,
making it useful as a scaffold for tissue engineering." Such
tissue engineering work has already started in collaboration
with Dr Ram Sharma from Chemical Engineering, also part of the
CSCT.

The researchers have also looked at using other sugars such as
ribose and mannose. Dr Buchard added: "Chemists have 100
years' experience with using petrochemicals as a raw material
so we need to start again using renewable feedstocks like
sugars as a base for synthetic but sustainable materials. It's
early days, but the future looks promising."

Polymers from sugars and
CO2: ring-opening polymerisation and copolymerisation of
cyclic carbonates derived from 2-deoxy-d-ribose.

Georgina L. Gregory, Gabriele Kociok-Köhn,
Antoine Buchard.

Abstract

Bio-based aliphatic polycarbonates (APCs) are attractive
synthetic materials for biomedical applications because of
their biodegradabilty and biocompatability properties. A high
yielding 3-step process that utilises CO2 as a C1 synthon is
presented for converting raw sugar, 2-deoxy-D-ribose into a
novel 6-membered cyclic carbonate for ring-opening
polymerisation (ROP) into carbohydrate-based APCs. The a- and
ß-anomers of the monomer could be isolated and revealed very
different polymerisability, as rationalised by DFT
calculations. Whereas the ß-anomer could not be polymerised
under the conditions tested, organocatalytic
homopolymerisation of the a-anomer, in solution at room
temperature (rt) or under melt conditions, yielded highly
insoluble polycarbonates, composed of both cyclic and linear
topologies, and exhibiting a glass transition temperature (Tg)
of ~58 °C. Random copolymers with controllable incorporation
of this new sugar monomer were prepared with trimethylene
carbonate (TMC) at rt in the bulk or in solution with Mn up to
64 000 g mol-1. With increasing sugar content, the Tg values
of the copolymers increased and their thermal degradability
was enhanced, giving access to a new class of APCs with
tailored properties.

AU2017202053Method of synthesising polycarbonates in the presence
of a bimetallic catalyst and a chain transfer agent

The invention provides a process for the synthesis of a
polycarbonate, the process comprising the step of reacting
carbon dioxide with at least one epoxide in the presence of a
catalyst of formula (I) and a chain transfer agent. The
invention also provides a polymerisation system for the
copolymerisation of carbon dioxide and at least one epoxide
comprising a catalyst of formula (I) and a chain transfer
agent, polycarbonates produced by the inventive process, a
block copolymer comprising a polycarbonate produced by the
inventive process and a method for producing the same. The
invention also relates to novel catalysts of formula (III)

As you’ll probably have seen from this morning’s headlines, UK
researchers running a clinical trial have presented some
exciting preliminary results at a the tenth European Breast
Cancer Conference.

The trial looked at the effects of combining two drugs –
trastuzumab (Herceptin) and lapatinib –before surgery, in
women with HER2 positive breast cancer.

Called EPHOS B, the trial was led by UK researchers in London
and Manchester, and funded by CRUK.

So what did these early results show, and why the excitement?

The pre-trial setting

When a woman is diagnosed with breast cancer, it is generally
classified as one of a number of subtypes. One of these is
called ‘HER2 positive’ breast cancer, because the cancer cells
have large amounts of a molecule called HER2 on their surface.

This means they’re more likely to respond to drugs designed to
target this molecule – including both trastuzumab and
lapatinib.

The treatment these women are offered depends on a number of
things, such as the stage of their breast cancer, whether they
are pre- or post-menopausal and their all-round general
health.

Some HER2 positive patients have chemotherapy with or without
trastuzumab (Herceptin) right away, to try and shrink their
tumour before surgery. Then after surgery, these women may
have more chemotherapy and maybe Herceptin to help stop the
cancer coming back.

Other women are scheduled to have surgery first, and are then
given an extensive course of chemotherapy combined with
Herceptin. Again, this is to help stop the cancer returning.

It’s this second group that the EPHOS B trial looked at.

The trial

EPHOS B included 257 women who had been diagnosed with HER2
positive breast cancer and were waiting to have surgery.

It was run in two parts. In the first, 130 women were assigned
to one of three groups – some received Herceptin
(trastuzumab), others received lapatinib. Both these groups
were treated for 11 days after diagnosis and before surgery. A
third group received no drug treatment before surgery (the
control group).

But, as often happens in science, other evidence became
available during the trial which showed that giving both drugs
together was better than either alone.

So the researchers changed tack. The next 127 women recruited
to the trial were assigned to either a control group, a
Herceptin only group, or group given a combination of
Herceptin and lapatinib.

Following their initial treatment, all women involved in the
trial went on to have standard care, including surgery.
The results

After surgery, the researchers analysed the resulting tissue
to see if there was a difference between the various groups.
They measured a variety of things in each sample, including
hallmarks of cell death and cell growth, and the size of any
remaining tumour tissue.

Excitingly, in tissue from seven of the 66 women who had the
combination treatment they saw what, in medical terms, is
known as a ‘pathological complete response’.

In non-medical terms, their tumours had gone.

And for another 11 women the drug combination shrank their
tumour considerably – these women are described as having
minimal residual disease – in other words, there were only
microscopic traces of the disease left over after treatment.

It’s important to remember that while this generally suggests
a treatment has worked well, it also means there are still
cancer cells remaining from which the disease could grow back.

This is especially important because HER2 positive breast
cancer is more likely to come back after treatment than some
other types of breast cancer.

But nevertheless, these are exciting results, particularly
when you consider that women with Stage 2 cancer – where the
cancer had spread to the lymph nodes – were among those who
responded to the combination therapy.

They’re also exciting when compared to the other groups in the
trial. No women given trastuzumab only, or no drug treatment,
had a complete response, while only one woman in the
trastuzumab-only group had minimal residual disease.

It’s also important to remember that the researchers didn’t
see any response in the other 48 women who received the drug
combination. Clearly, there’s something different about some
HER2 positive tumours that makes them exquisitely sensitive to
the drug combination.

The next steps

These results indicate that there’s a group of HER2 positive
breast cancer patients who are likely to derive big benefits
from receiving trastuzumab and lapatinib, and the researchers
running the trial think these same women may not need
chemotherapy after surgery.

But it’s too early to say this for sure – this needs to be
confirmed with longer follow-up and larger clinical trials.
And this needs to answer two key questions.

First, researchers and doctors have to come up with a way of
identifying those women who are more sensitive to pre-surgery
treatment.

Following this, they will need to run clinical trials to see
if these women really can avoid chemotherapy treatment and if
the current standard of care for some HER2 positive breast
cancer patients can and should be changed.

A pair of drugs can dramatically shrink and eliminate some
breast cancers in just 11 days, UK doctors have shown.

They said the "surprise" findings, reported at the European
Breast Cancer Conference, could mean some women no longer need
chemotherapy.

The drugs, tested on 257 women, target a specific weakness
found in one-in-ten breast cancers.

Experts said the findings were a "stepping stone" to tailored
cancer care.

The doctors leading the trial had not expected or even
intended to achieve such striking results.

They were investigating how drugs changed cancers in the short
window between a tumour being diagnosed and the operation to
remove it.

But by the time surgeons came to operate, there was no sign of
cancer in some patients.

Prof Judith Bliss, from the Institute of Cancer Research in
London, said the impact was "dramatic".

She told the BBC News website: "We were particularly surprised
by these findings as this was a short-term trial.

"It became apparent some had a complete response. It's
absolutely intriguing, it is so fast."

The drugs were lapatinib and trastuzumab, which is more widely
known as Herceptin.

They both target HER2 - a protein that fuels the growth of
some women's breast cancers.

Herceptin works on the surface of cancerous cells while
lapatinib is able to penetrate inside the cell to disable
HER2.

The study, which also took place at NHS hospitals in
Manchester, gave the treatment to women with tumours measuring
between 1 and 3cm.

In less than two weeks of treatment, the cancer disappeared
entirely in 11% of cases, and in a further 17% they were
smaller than 5mm.

Current therapy for HER2 positive breast cancers is surgery,
followed by chemotherapy and Herceptin.

But Prof Bliss believes the findings could eventually mean
some women do not need chemotherapy.

However, that will require larger studies especially as HER2
positive cancers have a higher risk of coming back.

"We would have to be very clear we're not taking a backwards
step and increasing the risk of relapse," Prof Bliss added.

Baroness Delyth Morgan, the chief executive at Breast Cancer
Now, said: "We hope this particularly impressive combination
trial will serve as a stepping stone to an era of more
personalised treatment for HER2 positive breast cancer.

"Such a rapid response to treatment could soon give doctors
the unprecedented ability to identify women responding so well
that they would not need gruelling chemotherapy."

Breast cancer is now thought of as at least ten separate
diseases, each with a different cause, life expectancy and
needing a different treatment.

Matching the specific errors in a tumour to targeted drugs is
considered the future of cancer medicine.

Breast cancers, and particularly HER2 positive tumours, are at
the forefront of this revolution in treatment.

Prof Arnie Purushotham, from Cancer Research UK which funded
the study, said: "These results are very promising if they
stand up in the long run, and could be the starting step of
finding a new way to treat HER2 positive breast cancers."

Case Western Reserve
embarks on innovative path to treat infections of
drug-resistant superbugs such as MRSA without antibiotics

School of Medicine’s biochemistry department team, in
partnership with Q2 Pharma, to develop antivirulence agents
that disarm bacteria of deadly toxins

Case Western Reserve University and Q2 Pharma Ltd., an Israeli
biopharmaceutical company, have signed a two-year option to
license small molecule, antivirulence technology with the
potential to treat bacterial infections such as
methicillin-resistant staphylococcus aureus (MRSA). Use of
these novel agents in patients could revolutionize the
treatment of bacterial infections.

“Superbugs” are bacteria that have developed resistance to
antibiotics for which current antibiotics are no longer
effective. Ever-increasing antibiotic resistance endangers
patients as doctors run out of treatment options.

The Centers for Disease Control and Prevention (CDC) report
that more than two million people develop antibiotic-resistant
infections in the U.S. every year, leading to 23,000 deaths.
Some experts say that without new inroads, the death toll
could top that from cancer or heart disease by 2050. The
financial costs are already enormous: as much as $20 billion
in extra health care spending annually.

“Superbugs threaten to undo many of the enormous health
advances brought about by the development of antibiotics since
penicillin was discovered by Alexander Fleming in 1928,” said
Menachem Shoham, associate professor of biochemistry at CWRU
School of Medicine, the scientist at the heart of the new
effort. “Our work represents a game changer to address this
mounting problem.”

Shoham and his research team have discovered and patented
non-antibiotic antivirulence compounds that prevent
disease-causing toxins from forming in gram-positive bacteria
such as MRSA. Since the antivirulent compounds don’t
jeopardize the survival of the bacteria, resistance isn’t
likely to occur, and has not been observed to date.

One of the Shoham team’s small-molecule compounds, named F19,
was effective in healing a MRSA skin infection in mice, and in
combination with an otherwise ineffective antibiotic, also
reduced bacterial presence in the wounds. F19 has also
demonstrated effectiveness against other gram positive
“Superbugs,” including the deadly Clostridium difficile (C.
diff.), Bacillus anthracis (the causative agent of anthrax),
Staphylococcus epidermidis typically infecting catheters and
implants, Streptococcus pyogenes (the causative agent of strep
throat) and Streptococcus pneumoniae, one of the causes of
acquired pneumonia and meningitis.

F19 works by binding to a protein involved in expressing
disease-causing toxins, thus preventing the bacteria from
producing the toxins. Without the toxins, the bacteria are
benign. F19 also blocks the formation of biofilms—the slimy
shells that bacteria encase themselves with for protection and
which antibacterial drugs can’t penetrate.

“By killing bacterial pathogens, antibiotics eventually induce
the organism to develop resistance,” said Shoham. “This is the
case with once-highly-effective antibiotics such as
penicillin. In contrast, our antivirulence agents strip the
bacteria pathogen of its ability to produce harmful toxins
without killing the pathogen. This results in little, if any,
need to develop resistance. Without the toxins, the bacteria
remain harmless, so people can go about their lives without
any sign of disease.”

While bacterial infections could be cured by anti-virulence
agents such as F19 without the need for antibiotics, in severe
cases or for immunocompromised patients, combination therapy
with a low-dose antibiotic may be appropriate. “The potential
drugs we developed have the additional benefit of enabling the
use of ‘old’ antibiotics in combination therapy,” said
Shoham...

US2015290227USE OF HAMAMELITANNIN FOR THE
TREATMENT OF STAPHYLOCOCCAL INFECTIONS

.
RNAIII inhibiting peptide (RIP) has been established as an
effective inhibitor of staphylococcal infections. Non-peptide
small molecule analogs based on a pharmacophore conforming to
the putative atomic structure of RIP, can be identified by
computer screening of that pharmacophore against established
libraries of known small molecules other than peptides. One
such identified structural analog is hamamelitannin. When
tested for effective inhibition of staphylococcal infections,
hamamelitannin demonstrated inhibition similar to that
exhibited by RIP. Other analogs can be identified and
similarly used.

US2015265550ANTI-VIRULANCE COMPOSITIONS AND
METHODS

A method of reducing the virulence of a bacterium that
expresses accessory gene regulator A (AgrA) or an ortholog of
AgrA includes administering to the bacterium an amount of a
pharmaceutical composition effective to inhibit the synthesis
of one or more virulence factors by the bacterium, the
pharmaceutical composition including an AgrA antagonist.

US8859626ANTI-VIRULENCE COMPOSITIONS AND
METHODS

A method of reducing the virulence of a bacterium that
expresses accessory gene regulator A (AgrA) includes
administering to the bacterium an amount of AgrA antagonist
effective to inhibit the synthesis of one or more virulence
factors by the bacterium.

Hungarian Prime Minister Viktor Orban about EU migrants
crisis. How to solve EU migrants crisis.
Stay in EU or leave EU.
"This is not a refugee crisis! This is a migratory movement
with economic migrants, refugees and foreign fighters."
"Europe is not able to accept everyone who wants a better
life"
"Listen to the people, defend Europe"

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