His acting career began on Broadway in the late 1940s, and he graduated to television while still maintaining a presence in the theater. His stage credits included Bye Bye Birdie, A Man for All Seasons, Annie Get Your Gun.

In the 1960s, Wertimer moved to Los Angeles to focus on his television career. He made his debut on The Jeffersons as Ralph, the doorman who was "always looking for a tip" in 1975.

Wertimer is survived by his wife, Skyne; a sister in law; a niece and three nephews.