Moderate drinking doesn’t make women less fertile

While moderate drinking—fewer than 14 servings of alcohol a week—doesn’t appear to affect a woman’s ability to get pregnant, the same may not be true for heavy drinking.

The results are based on a study of 6,120 Danish women who were in stable relationships with male partners and who were trying to conceive. Participants were asked in detail about their overall alcohol consumption, as well as intake of specific types of alcoholic beverages, including beer, wine, and liquor.

The researchers followed the women over nine years and adjusted for a number of factors, including time and frequency of intercourse. By the end of the study, 4,210 participants (69 percent) achieved a pregnancy.

The study, published by the BMJ, found that moderate drinkers were no less likely to conceive than those who abstained completely. Heavier drinking—the equivalent of two bottles of wine or more a week—was associated with an 18 percent decrease in fecundity.

The results come amid controversy, in the US and other countries, over official guidelines recommending that women trying to become pregnant should abstain from alcohol consumption. In early 2016, the Centers for Disease Control and Prevention issued a report suggesting that women who intended to get pregnant or those who were at risk of pregnancy should not drink any alcohol, saying, “There is no safe time during pregnancy to drink. All types of alcohol are equally harmful, including all wines and beer. When a pregnant woman drinks alcohol, so does her baby.”

The new study’s findings “did not support an effect of alcohol consumption at more moderate levels,” the authors write. “We observed no appreciable differences in the associations of consumption of beer and wine with fecundability,” while there was a slight reduction in fertility among women who drank only hard liquor.

The researchers still recommend that couples abstain from alcohol during their “fertile window” until a pregnancy is ruled out, because the fetus may be particularly vulnerable to alcohol during the first few weeks after conception.

“While the advice to completely abstain from alcohol during pregnancy is well-justified, our results suggest that moderate drinking does not harm fertility,” says study coauthor Elizabeth Hatch, a principal investigator on the Danish study and professor of epidemiology at Boston University School of Public Health.

“Because all reproductive-aged women are potentially at risk of pregnancy, the CDC’s recommendations seem a bit impractical, although clearly excessive drinking should be avoided,” she says.

The study did not collect information about the alcohol intake of male partners, which is known to affect sperm quality. And, while the sample size was large, only 1.2 percent of women reported drinking more than 14 servings of alcohol a week, so estimates for high levels of consumption may be imprecise, the authors caution.

Ellen Mikkelsen, a senior researcher at Aarhus University, led the study. The National Institute of Child Health and Human Development and the Danish Medical Research Council funded the work.