Human SCN1A Stable Cell Line-HEK293

The voltage gated sodium channel isoform Nav1.1 is involved with axon potential initiation and repetitive neuronal firing as well as the contraction-excitation coupling of cardiac myocytes. Nav1.1 is the target of antiepileptic drugs and the probable target causing side effects of centrally active local anaesthetics. It is detected cardiac myocytes as well as in the cell bodies of central neurons.