MOPAC2012 is a semiempirical quantum chemistry program for the prediction of chemical properties and modeling of chemical reactions, now with the new PM7 method and giant molecule capability. MOPAC2012 is command-line driven and can be used with a wide variety of third-party GUIs. Prerequisites: none
Platforms: Windows, Mac, Linux

EMPIRE is a completely new semiempirical molecular orbital program designed to run in parallel on multi-core desktop computers and on massively parallel supercomputers, and includes s-, p- and d-orbitals in the basis set with the core-core functions from MNDO, MNDO/d (also PM6 and AM1*), and AM1 (also AM1*, PM3, PM6). It has been tested with 76,800 atoms on 1,024 processors. availability Q4, 2012