Chlorpromazine, a phenothiazine derivative classified as a low-potency typical antipsychotic is indicated for the treatment of schizophrenia. The therapeutic effect is thought to be due to blocking of postsysnaptic dopamine D2 receptor subtype in the mesolimbic pathway.
Antagonism of dopamine receptors is also associated with extrapyramidal effects such as akathisia, dystonia and tardive dyskinesia and elevated serum prolactin.Chlorpromazine has also antiadrenergic, anticholinergic, antihistaminic and antiserotonin activity.Chlorpromazine acts also as an antiemetic

Use in Lactation: Chlorpromazine has been found to be excreted in breast milk in variable amounts, therefore it is not recommended for nursing mothers unless the expected benefits outweigh any potential risk.