anti-SMAD, Mothers Against DPP Homolog 5 (SMAD5) Antibodies

The protein encoded by SMAD5 is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. Additionally we are shipping SMAD5 Proteins (14) and SMAD5 Kits (8) and many more products for this protein.

this study uncovers that smad1 (show SMAD1 Antibodies) and smad9 (show SMAD9 Antibodies) act redundantly to each other downstream of smad5 to mediate ventral specification and to regulate embryonic myelopoiesis.

Here the involvement of the pathway in adult brain function is suggested. This exploratory study establishes a strategy to better identify neuronal molecular signatures that are potentially associated with mental illness and cognitive deficits. We propose that the SMAD (show SMAD1 Antibodies) pathway may be a novel target in addressing cognitive deficit of SZ in future studies.

among the 15 SNPs, rs3206634 was significantly associated with KD in a recessive model (odds ratio = 2.31, p = 0.019), whereas there was no association between any of the 15 SNPs and CALs (show CA8 Antibodies).

miR (show MLXIP Antibodies)-155 inhibited osteoblast differentiation by downregulating the translation of SMAD5 in mouse preosteoblast cells. Inhibition of miR (show MLXIP Antibodies)-155 promoted osteogenic potential and thus it can be used as a potential target in the treatment of bone defects.

Up-regulation of miR (show MLXIP Antibodies)-93 may contribute to the progression of morphine tolerance by targeting Smad5 in mouse model of bone cancer pain

SMAD5 Antigen Profile

Protein Summary

The protein encoded by this gene is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by BMP type 1 receptor kinase. Three transcript variants encoding the same protein have been found for this gene.