0. DOCID:27601 SCORE: 0.00234078379696054DOCNO: 15687572OWNER: NLMSTATUS: PubMed-not-MEDLINEAUTHOR: R L Wahl RLAFFILIATION: University of Michigan Medical Center, Ann Arbor, MI 48109-0028, USA.PUBTYPE: Journal ArticleJOURNALTITLE: Breast disease. COUNTRY: NetherlandsTITLE: Positron Emission Tomography (PET): an update on applications in breast cancer.PUBDATE: 19980801
Positron Emission Tomography (PET) is an imaging method which detects alterations in tumor physiology and displays them in an anatomically precise manner. Historically, the method has been a research tool, but it is being increasingly applied to clinical imaging problems. PET, using the glucose analog 18-F-fluoro-2-deoxy-D-glucose (FDG), has been applied most widely and shows promise in detecting primary cancers, characterizing breast masses, staging for axillary metastases, evaluating for systemic metastases, and following response to therapy. This review summarizes the current status of this technique, which is in rapid evolution as new tracers and new imaging cameras become available.

1. DOCID:25758 SCORE: 0.00182842893210269DOCNO: 10388857OWNER: NLMSTATUS: MEDLINEDESCRIPTOR: StentsQUALIFIER: surgeryQUALIFIER: surgeryQUALIFIER: instrumentationAUTHOR: W Mayoral WAUTHOR: D E Fleischer DEAFFILIATION: Department of Medicine, Division of Gastroenterology, Georgetown University Medical Center, Washington, District of Columbia, USA.PUBTYPE: Journal ArticlePUBTYPE: ReviewJOURNALTITLE: Gastrointestinal endoscopy clinics of North America. COUNTRY: UNITED STATESTITLE: The esophacoil stent for malignant esophageal obstruction.PUBDATE: 19990701
Esophageal cancer is the seventh most common cause of cancer-related deaths in men in the United States. For a disease in which 60% of patients are incurable at presentation, palliative therapy is the main treatment option. Palliative measures include surgery, radiation therapy, chemotherapy, photodynamic therapy, endoscopic dilation, endoscopic ablation, and the use of endoscopic prostheses. This article reviews the characteristics, technique, efficacy, and complications of the Esophacoil stent for malignant esophageal strictures.

2. DOCID:27578 SCORE: 0.0014058954249173DOCNO: 10688731OWNER: NLMSTATUS: MEDLINEQUALIFIER: adverse effectsQUALIFIER: adverse effectsQUALIFIER: chemically inducedQUALIFIER: adverse effectsQUALIFIER: adverse effectsAUTHOR: T Kono TAUTHOR: M Ishii MAUTHOR: N Negoro NAUTHOR: S Taniguchi SAFFILIATION: Department of Dermatology, First Department of Internal Medicine, Osaka City University Medical School, Japan.PUBTYPE: Case ReportsPUBTYPE: Journal ArticleJOURNALTITLE: Journal of the American Academy of Dermatology. COUNTRY: UNITED STATESTITLE: Scleroderma-like reaction induced by uracil-tegafur (UFT), a second-generation anticancer agent.PUBDATE: 20000301
UFT, a combination of uracil and tegafur, is a second-generation anticancer agent. UFT has been used in Japan, other Asian countries, South America, and Russia. Recently, UFT has been extensively studied for colorectal, pancreatic, and various types of cancer in North America and Europe, especially with leukovorin. We report a case of a scleroderma-like reaction induced by long-term administration of UFT. This is the first report of UFT-induced scleroderma-like reaction.

3. DOCID:27165 SCORE: 0.00139316512382265DOCNO: 10865513OWNER: NLMSTATUS: MEDLINEDESCRIPTOR: Breast ImplantationDESCRIPTOR: Magnetic Resonance ImagingDESCRIPTOR: MammographyQUALIFIER: transplantationQUALIFIER: diagnosisQUALIFIER: diagnosisQUALIFIER: diagnosisAUTHOR: M Unterweger MAUTHOR: C Meuli-Simmen CAUTHOR: R Caduff RAUTHOR: R A Kubik-Huch RAAFFILIATION: Institut für Diagnostische Radiologie, Universitätsspitals Zürich. martin.unterweger@dmr.usz.chPUBTYPE: Case ReportsPUBTYPE: Journal ArticleJOURNALTITLE: Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine Praxis. COUNTRY: SWITZERLANDTITLE: [Breast imaging after augmentation with homologous adipose tissue implant]PUBDATE: 20000501
The implantation of cadaveric fat for breast augmentation, which has been performed up to the Seventies, is nowadays considered obsolete. Since complications frequently arise many years later, we are, however, occasionally confronted with the problematic consequences of the technique. The present case report describes the clinical, mammographic and for the first time to our knowledge MR-mammographic findings of a mammoplasty with cadaveric fat in a 57-year-old patient with a history of breast cancer.

7. DOCID:26587 SCORE: 0.00110031698799076DOCNO: 10966851OWNER: NLMSTATUS: MEDLINEQUALIFIER: geneticsAUTHOR: L A Aaltonen LAAFFILIATION: Department of Medical Genetics, University of Helsinki, P.O. Box 21, FIN-00014, Finland.PUBTYPE: Journal ArticlePUBTYPE: ReviewJOURNALTITLE: Seminars in cancer biology. COUNTRY: UNITED STATESTITLE: Hereditary intestinal cancer.PUBDATE: 20000801
Mechanisms involved in hereditary intestinal cancer are likely to play a role in sporadic tumorigenesis as well. Studies focusing on the molecular biology underlying these syndromes has contributed considerably to our knowledge on molecular bases of malignant transformation. It can be concluded, that there are two aspects to the importance of studies on intestinal cancer predisposition. First, the families suffering from cancer proneness need help which can, to some extent, be provided through molecular genetic studies. Second, the resources appointed to such research have produced scientific advances with outstanding importance to our understanding of common malignant diseases.

9. DOCID:26207 SCORE: 0.00107027841601336DOCNO: 11263852OWNER: NLMSTATUS: MEDLINEDESCRIPTOR: Estrogen Replacement TherapyDESCRIPTOR: MenopauseDESCRIPTOR: Menopause, PrematureQUALIFIER: drug therapyAUTHOR: H C Moore HCAFFILIATION: Department of Hematology and Medical Oncology, Cleveland Clinic, Cleveland Clinic Foundation, OH 44195, USA. mooreh1@ccf.orgPUBTYPE: Journal ArticleJOURNALTITLE: Cleveland Clinic journal of medicine. COUNTRY: United StatesTITLE: Managing menopause after breast cancer: balancing risks and benefits.PUBDATE: 20010301
Many women now survive breast cancer, but find themselves at increased risk of menopausal complications. How to manage menopause after breast cancer is a complex issue, given that estrogen has a role in the development of breast cancer and valid concerns exist about estrogen replacement therapy in patients who have had breast cancer. This article explores the relationship between estrogens and breast cancer and discusses management options for a variety of menopausal complications in breast cancer survivors.

10. DOCID:27734 SCORE: 0.000939981641152905DOCNO: 9696939OWNER: NLMSTATUS: MEDLINEDESCRIPTOR: CerealsDESCRIPTOR: Dietary FiberQUALIFIER: epidemiologyAUTHOR: C La Vecchia CAUTHOR: L Chatenoud LAFFILIATION: Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.PUBTYPE: Journal ArticlePUBTYPE: ReviewJOURNALTITLE: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP). COUNTRY: ENGLANDTITLE: Fibres, whole-grain foods and breast and other cancers.PUBDATE: 19980501
The possible relationship between fibre intake and breast cancer risk has been considered in several studies, but the issue is still unsettled. Epidemiological data are compatible with moderate protection from fibre-rich foods against the risk of breast cancer, but also with an absence of association. The apparently inconsistent results may be due to chance or bias, to different approaches to data analysis and interpretation, but may also reflect heterogeneity in the dietary sources of fibres (cereals or vegetables and fruit) in various populations, and different correlates of fibre intake.

11. DOCID:27952 SCORE: 0.000935431588142589DOCNO: 9690990OWNER: NLMSTATUS: MEDLINEQUALIFIER: geneticsAUTHOR: A de la Chapelle AAUTHOR: P Peltomäki PAFFILIATION: Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA. delachapelle-1@medctr.osu.eduPUBTYPE: Journal ArticlePUBTYPE: ReviewJOURNALTITLE: Current opinion in genetics & development. COUNTRY: ENGLANDTITLE: The genetics of hereditary common cancers.PUBDATE: 19980601
Subsets of patients with common cancers belong to families in which the predisposition is inherited in a regular Mendelian fashion. Genes underlying these cancers are now recognized in colorectal cancer (APC, mismatch repair genes, LKB1) and in breast cancer (BRCA1, BRCA2) whereas, in prostate cancer, a locus in chromosome 1 (HPC1) has been proposed on the basis of linkage analysis. Major challenges are to determine the population incidence of these mutations, their penetrance, phenotypic expression, and the effects of modifier genes and epigenetic factors. Finally, the role of encoded proteins in carcinogenesis is a matter of major interest.

12. DOCID:27033 SCORE: 0.000866126026644951DOCNO: 11219976OWNER: NLMSTATUS: MEDLINEQUALIFIER: administration & dosageQUALIFIER: nursingQUALIFIER: methodsAUTHOR: E Hollywood EAUTHOR: D Semple DAFFILIATION: Gastrointestinal Oncology Service, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.PUBTYPE: Journal ArticlePUBTYPE: ReviewJOURNALTITLE: Oncology (Williston Park, N.Y.) COUNTRY: United StatesTITLE: Nursing strategies for patients on oral chemotherapy.PUBDATE: 20010101
Oncology nurses play a pivotal role in educating the cancer patient who is about to commence oral chemotherapy. Increasing numbers of patients are receiving oral chemotherapy at home, and with this move to oral self-administration, there has been a critical shift in responsibility of management from the provider to patient. Oral regimens pose new challenges in patient selection and education. Recognition of factors that affect patient compliance will be particularly important with oral chemotherapy. Strategy tools for the patient and provider will need to be developed to ensure optimal compliance and safety.

13. DOCID:26046 SCORE: 0.000837937738671628DOCNO: 11204368AUTHOR: P Jain PAUTHOR: A C Arroliga ACAFFILIATION: Department of Medicine, Louis A. Johnson VA Medical Center, Clarksburg, West Virginia 26301, USA. rrpj@msn.comPUBTYPE: Journal ArticlePUBTYPE: ReviewJOURNALTITLE: Cleveland Clinic journal of medicine. COUNTRY: United StatesTITLE: Spiral CT for lung cancer screening: is it ready for prime time?PUBDATE: 20010101
Low-dose spiral computed tomography (CT) shows promise as a screening test for lung cancer, as it detects many more malignant pulmonary nodules than does standard plain radiography of the chest. Yet until more data are available we need to temper our enthusiasm. No studies have yet determined if using low-dose spiral CT as a screening test will lead to lower mortality rates. This paper reviews the issue of lung cancer screening and low-dose spiral CT.

14. DOCID:26155 SCORE: 0.00083690435586445DOCNO: 10349817OWNER: NLMSTATUS: MEDLINEQUALIFIER: metabolismQUALIFIER: metabolismQUALIFIER: metabolismQUALIFIER: metabolismAUTHOR: M Uszyński MAFFILIATION: Katedry i Zakładu Propedeutyki Medycyny Akademii Medycznej w Bydgoszczy.PUBTYPE: Journal ArticlePUBTYPE: ReviewJOURNALTITLE: Ginekologia polska. COUNTRY: POLANDTITLE: [Fibrinolytic substances formation by cancer. Pathogenetic sequelae]PUBDATE: 19990201
A survey of literature has been presented relating to fibrinolytic substances secreted by malignant tumors, and the role of those substances in the progression of cancer. Particular attention has been given to the effects of plasmin proteolysis which is generated in the extracellular matrix by urokinase plasminogen activator (uPA) complexed with its receptor (uPAR). The paper also discusses the usefulness of the markings of the substances under discussion for diagnostic-prognostic purposes, and a perspective of using the new research in therapy, for example, by using antibodies anti-uPA and anti-uPAR.