A review of official reports of bad drug reactions is revealing more signs that people taking the diabetes drug Actos are at higher risk of developing bladder cancer. Between 2004 and 2009, more than half a million adverse reactions among people taking anti-diabetic drugs were added to an official U.S. Food and Drug Administration database. Among those reports were 138 instances of bladder cancer in patients taking at least one of more than 15 different anti-diabetic drugs.