depression - an extreme mood of sadness with physical symptoms such as loss of appetite and sleep.

Depression and Bipolar Support Alliance - A not-for-profit organization established to: Educate patients, families, mental health professionals, and the general public concerning the nature and management of depressive and manic-depressive illness as treatable medical diseases; foster self-help for patients and families; eliminate discrimination and stigma; Improve access to care; advocate for research toward the elimination of these illnesses.