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Article Abstract

Nonadherence to medication is one of the major problems in treating patients with schizophrenia.
Clinicians can use a variety of assessment strategies to identify patients who are nonadherent,
although none of these is completely reliable. Interventions to improve adherence include psychosocial
strategies, second-generation oral antipsychotics, and long-acting injectable antipsychotics. Because
of the potential for reduced relapse and rehospitalization rates and the availability of second–generation antipsychotics in injectable form, a case is made for using long-acting injectable
second-generation antipsychotics, when appropriate, to treat patients with schizophrenia.