In 1980, in his senior year at the University of Denver, Noel Ginsburg founded Intertech Plastics, a custom injection molding business, manufacturing products for the consumer, packaging, industrial and medical device markets. The company employs over 200 people and operates twenty-four hours a day, seven days a week.

Ginsburg is founding Chairman of the Board for CareerWise Colorado, a statewide nonprofit organization dedicated to building the middle class by closing the skills gap through experiential learning. CareerWise Colorado is building a system of youth apprenticeships across a variety of industries to ensure businesses have a capable workforce and students have a clear career path.

Ginsburg was the founding chair of the Colorado Advanced Manufacturing Alliance (CAMA) and currently serves on its board and executive committee. The Alliance is focused on building manufacturing and manufacturing jobs in the State of Colorado. In addition, Ginsburg is a member of the State Economic Development board, a board member of the Denver Metro Chamber of Commerce, co-chair of The Leadership Initiative, chair of the Denver Public Schools College and Career Pathways council, member of the US Youth Employment Action Network at the Clinton Global Initiative and was appointed by Governor Hickenlooper to lead the Business Experiential Learning (BEL) Commission for the State of Colorado.

Ginsburg has served as the board chair and general campaign chair of the Mile High United Way and the Allied Jewish Federation of Colorado and served as President of the Denver Public Schools Foundation.

Ginsburg was among the founding board members and is a past President of the Colorado I Have a Dream Foundation. Ginsburg has received numerous awards for his civic engagement and public service.