superfinn

2 years ago

BRCA1 mutation
BRCA2 mutation
No BRCA mutation
Total
Number of patients
89
35
318
442
Average age at diagnosis
43.9
46.2
50.4
Preventative mastectomy*
6
3
14
23
Preventative oophorectomy*
38
7
22
67
Number of deaths
16
1
21
38
Percent died
18
2.8
6.9
8.6
*A mastectomy is the surgical removal of one or both breasts, either partially of fully. An oophorectomy is the surgical removal of an ovary or ovaries.

BRCA1 mutation
BRCA2 mutation
No BRCA mutation
Total
Number of patients
89
35
318
442
Average age at diagnosis
43.9
46.2
50.4
Preventative mastectomy*
6
3
14
23
Preventative oophorectomy*
38
7
22
67
Number of deaths
16
1
21
38
Percent died
18
2.8
6.9
8.6
*A mastectomy is the surgical removal of one or both breasts, either partially of fully. An oophorectomy is the surgical removal of an ovary or ovaries.
Things to address in your summary essay:
Describe how mutations lead to genetic variations.
Which appears to be more dangerous: the BRC1 or BRC2 mutation?
Analyze a woman’s risk of dying of cancer if she carries a mutated BRC1 gene.
How do heredity and inheritance relate to the data presented in these charts?
What data would you need to see in order to draw conclusions about the effectiveness of preventive surgeries?
What does the age at diagnosis tell you about the mutation?
Explain how breast-cancer genes are still present in the population, despite cancer-related surgeries and deaths.

the whole thing... i have the chart but this is what it wants me to do
Describe how mutations lead to genetic variations. Which appears to be more dangerous: the BRC1 or BRC2 mutation? Analyze a woman’s risk of dying of cancer if she carries a mutated BRC1 gene. How do heredity and inheritance relate to the data presented in these charts? What data would you need to see in order to draw conclusions about the effectiveness of preventive surgeries? What does the age at diagnosis tell you about the mutation? Explain how breast-cancer genes are still present in the population, despite cancer-related surgeries and deaths.

you need to do some research yourself first, i mean the first question you can basically google.
the second, just compare the data and see which percentage has the higher mortality rate
the third, just see what the percentage of deaths for the BRC1 mutation there were in the study
etc