Outline

Project List

Conceptual questions

In the abstract level, how could we live with imperfect efficiency? No matter writing mechanism we choose in the end, the fraction of cells whose genome is actually rewritten will likely to be significantly less than a hundred percent.

What are the common/ different challenges between writing memory to DNA versus gene therapy/ transgenic?

TO DO List

Write up the detail structure and mechanism of integrase

Take a look at how virus hijack a host and take control of host machinery (i.e. look at Covert's large

scale viral-bacterial models). May be the first step for engineering a cell it to modify the virus to control the cell the way we want.