Latisse

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Latisse

PATIENT INFORMATION

LATISSE® [la teece]
(bimatoprost) Ophthalmic Solution 0.03%

Read the Patient Information that comes with LATISSE® before
you start using it and each time you get a refill. There may be new
information. This leaflet does not take the place of talking with your
physician about your treatment.

What is hypotrichosis of the eyelashes?

Hypotrichosis is another name for having inadequate or
not enough eyelashes.

What is LATISSE® solution?

LATISSE® solution is a prescription treatment for
hypotrichosis used to grow eyelashes, making them longer, thicker and darker.

Who should NOT take LATISSE®?

Do not use LATISSE® solution if you are allergic
to one of its ingredients.

Are there any special warnings associated with LATISSE®
use?

LATISSE® solution is intended for use on the
skin of the upper eyelid margins at the base of the eyelashes. Refer
to Illustration 2 below. DO NOT APPLY to the lower eyelid. If you are using LUMIGAN® or other products in the same class for elevated intraocular pressure
(IOP), or if you have a history of abnormal IOP, you should only use LATISSE® under the close supervision of your physician.

LATISSE® use may cause darkening of the eyelid
skin which may be reversible. LATISSE® use may also cause increased
brown pigmentation of the colored part of the eye which is likely to be
permanent.

It is possible for hair growth to occur in other areas of
your skin that LATISSE® frequently touches. Any excess solution outside
the upper eyelid margin should be blotted with a tissue or other absorbent
material to reduce the chance of this from happening. It is also possible for a
difference in eyelash length, thickness, fullness, pigmentation, number of
eyelash hairs, and/or direction of eyelash growth to occur between eyes. These
differences, should they occur, will usually go away if you stop using LATISSE®.

Who should I tell that I am using LATISSE®?

You should tell your physician you are using LATISSE® especially
if you have a history of eye pressure problems.

You should also tell anyone conducting an eye pressure
screening that you are using LATISSE®.

What should I do if I get LATISSE® in my eye?

LATISSE® solution is an ophthalmic drug product. LATISSE® is not expected to cause harm if it gets into the eye proper. Do not
attempt to rinse your eye in this situation.

What are the possible side effects of LATISSE®?

The most common side effects after using LATISSE® solution
are an itching sensation in the eyes and/or eye redness. This was reported in
approximately 4% of patients. LATISSE® solution may cause other less
common side effects which typically occur on the skin close to where

LATISSE® is applied, or in the eyes. These include
skin darkening, eye irritation, dryness of the eyes, and redness of the
eyelids.

If you develop a new ocular condition (e.g., trauma or
infection), experience a sudden decrease in visual acuity, have ocular surgery,
or develop any ocular reactions, particularly conjunctivitis and eyelid
reactions, you should immediately seek your physician's advice concerning the
continued use of LATISSE® solution.

What happens if I stop using LATISSE®?

If you stop using LATISSE®, your
eyelashes are expected to return to their previous appearance over several
weeks to months.

Any eyelid skin darkening is expected to reverse after
several weeks to months.

Any darkening of the colored part of the eye known as the
iris is NOT expected to reverse and is likely permanent.

How do I use LATISSE®?

The recommended dosage is one application nightly to the
skin of the upper eyelid margin at the base of the eyelashes only.

Once nightly, start by ensuring your face is clean,
makeup and contact lenses are removed. Remove an applicator from its tray.
Then, holding the sterile applicator horizontally, place one drop of LATISSE® on the area of the applicator closest to the tip but not on the tip (see
Illustration 1). Then immediately draw the applicator carefully across the skin
of the upper eyelid margin at the base of the eyelashes (where the eyelashes
meet the skin) going from the inner part of your lash line to the outer part (see
Illustration 2). Blot any excess solution beyond the eyelid margin. Dispose of
the applicator after one use.

Repeat for the opposite upper eyelid margin using a new
sterile applicator. This helps minimize any potential for contamination from
one eyelid to another.

Illustration 1

Illustration 2

DO NOT APPLY in your eye or to the
lower lid. ONLY use the sterile applicators supplied with LATISSE® to
apply the product. If you miss a dose, don't try to “catch up.” Just apply LATISSE® solution the next evening. Fifty percent of patients treated with LATISSE® in a clinical study saw significant improvement by 2 months after starting
treatment.

If any LATISSE® solution
gets into the eye proper, it is not expected to cause harm. The eye should not
be rinsed.

Don't allow the tip of the
bottle or applicator to contact surrounding structures, fingers, or any other
unintended surface in order to avoid contamination by common bacteria known to
cause infections.

Contact lenses should be
removed prior to application of LATISSE® and may be reinserted 15
minutes following its administration.

Use of LATISSE® more
than once a day will not increase the growth of eyelashes more than use once a
day.

Store LATISSE® solution
at 36-77°F (2-25°C).

General Information about LATISSE®

Prescription treatments are
sometimes prescribed for conditions that are not mentioned in patient
information leaflets. Do not use LATISSE® solution for a condition for
which it was not prescribed. Do not give LATISSE® to other people. It
may not be appropriate for them to use.

This leaflet summarizes the
most important information about LATISSE® solution. If you would like
more information, talk with your physician. You can also call Allergan's
product information department at 1-800-433-8871.