I'm having an odd problem where I have a master page with guides. The guides show up in some pages with that master, but doesn't show up in others with that same master. And on the ones that it doesn't show up in, I can't drag a new guide onto those pages - it just disappears once I let go of it. On the ones it does show up in, I can drag new ones on. However, even on the pages where I can't see/add the blue guides, I can see the pink margins.

Take a look at the "Preferences -> Guides & Pasteboard -> Guide Options". See whether "Guides in Back" is on. When this option is active, guides stay behind all the opaque elements. Maybe some pages of your document have images or colored frames over the guides; that's why you're not seeing them.

No, "Guides in Back" isn't checked and I mostly have type on the page so there's nothing much to block the guides.

I'm just creating new pages for those without guides that I need to edit, cutting/pasting the content from the old one, and getting rid of the buggy pages. It's faster than trying to figure it out - it was frustrating, now mostly just puzzling. :-/

No, I'm not saving as IDML nor has it ever been. It's always been an indd file in the same version of indd, though has been passed between me and another person. The doc has only 1 layer that's visible. And yes, I checked threshold % through the layout menu. I actually didn't know it was in preferences but since I zoomed in 4000% and still couldn't see them (and can see them on other pages) I don't think that's the problem.

@Bob: Strange. I also opened the file in ID CC and had the exact same issues the original poster was having. Page 4, for example, which she labeled with "THIS SCREEN HAS NO GUIDES! WHY?", shows no guide at all. And if I try to insert a new guide in that page, the guide instantly disappear.

Ok thanks. I guess it's just corrupted - which is another can of worms. My InDesign crashes at least once a day and often brings down my whole system with 100%+ cpu usage and 'not responding' messages. But after years, multiple CS versions, deleting prefs, reinstall, turning off autochecks, etc - I've given up trying to figure that out. Perhaps i should I post a crash report here? http://forums.adobe.com/thread/961326

Or if there's a topic anyone knows off-hand, I'd appreciate the referral or can start a new one. Perhaps I'll try figuring it out again.

I pasted a couple crash reports and a sample process from Activity Monitor when my system was 'not responding'. Today I had a crazy problem where I found elements missing and images placed way off in the pasteboard outside of their visible frames. I might have inadvertantly moved or deleted elements, but it's very random and on multiple frames. Trying to rebuild these pages and make the images visible again (by using fit content to frame) is what's causing the crashing today. Any insight appreciated...