适于 ADAMTS7 相互作用对的更多 ELISA 试剂盒

Therefore, these data provided the in vivo evidence, suggesting that ADAMTS-7 may play an important role in the pathogenesis of inflammatory arthritis.

Mice lacking Adamts7, Ldlr, Apoe had less lesion formation in aortas and aortic roots vs controls and less neointimal formation after femoral wire injury. Adamts7 expression was induced by injury and hyperlipidemia.

Adamts-7 deficiency substantially ameliorated neointima formation in mice at days 14 and 28 after injury. ADAMTS-7 inhibited both endothelial cell proliferation and migration.

ADAMTS-7 and TNF-alpha (显示 TNF ELISA试剂盒) form a positive feedback loop in the regulation of cartilage degradation and osteoarthritis progression.

ADAMTS7B has a domain organization with a total of eight thrombospondin type 1 repeats in its ancillary domain. Of these, seven are arranged in two distinct clusters that are separated by a mucin (显示 SLC13A2 ELISA试剂盒) domain

Our results indicate the presence of ADAMTS-7 in human NP cells and imply its potential role in disc degeneration.

The main contribution of this study is the proposal of a pharmacophore for ADAMTS7.

The significant associations observed between this coding variant in ADAMTS7 and the risk of CAD (显示 CAD ELISA试剂盒) development.

Logistic regression analysis indicated that the association between ADAMTS-7 and heart failure after AMI (显示 CFD ELISA试剂盒) was independent from traditional cardiovascular risk factors and other biomarkers

Data conclude that ADAMTS-7 level appears to be positively associated with expression of TNF-alpha (显示 TNF ELISA试剂盒) and Phospho-NF-kappaB (显示 NFKB1 ELISA试剂盒) P65 (显示 GORASP1 ELISA试剂盒) in cartilage, which may imply its association with cartilage destruction of ONFH.

ADAMTS7 localized to cells having smooth muscle cell markers in human coronary artery disease lesions. Cultured vascular smooth muscle cells had ADAMTS7 at the cytoplasm and cell membrane, where it colocalized with markers of podosomes.

ADAMTS7 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two C-terminal TS motifs.