Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Recombinant Human Interleukin-18 is produced by our E. coli expression system and the target gene encoding Tyr37-Asp193 is expressed.

Region:

Tyr37-Asp193

AA Sequence:

YFGKLESKLS

VIRNLNDQVL

FIDQGNRPLF

EDMTDSDCRD

NAPRTIFIIS

MYKDSQPRGM

AVTISVKCEK

ISTLSCENKI

ISFKEMNPPD

NIKDTKSDII

FFQRSVPGHD

NKMQFESSSY

EGYFLACEKE

RDLFKLILKK

EDELGDRSIM

FTVQNED

Expression System:

E. coli

Source Species:

E. coli

Tag:

None

Purification:

Greater than 95% by SDS-PAGE

Bio-Activity:

Not Tested

Endotoxin:

Less than 1.0 EU/µg protein (determined by LAL method).

Presentation:

Lyophilized from 0.2 µm filtered PBS, pH 7.4.

Storage:

Lyophilized protein should be stored at less than -20°C. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at less than -20°C for 3 months.