MoTrPAC is a national research consortium designed to discover and perform preliminary characterization of the
range of molecular transducers (the "molecular map") that underlie the effects of physical activity in humans.
The program's goal is to study the molecular changes that occur during and after exercise and ultimately to advance the
understanding of how physical activity improves and preserves health. The six-year program is the largest targeted NIH
investment of funds into the mechanisms of how physical activity improves health and prevents disease.

The MoTrPAC program is supported by the NIH Common Fund and is managed by a trans-agency working group representing multiple
NIH institutes and centers, led by the NIH Office of Strategic Coordination, National Institute of Arthritis and Musculoskeletal
and Skin Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute on Aging, and National
Institute of Biomedical Imaging and Bioengineering.