The Mekon (of Mekonta) is the arch-enemy of the Britishcomic book hero Dan Dare, first appearing in 1950 in the Eaglecomic stripDan Dare, Pilot of the Future and created by Frank Hampson. Apart from Dan Dare himself, he is the only character to appear in every one of the numerous versions of the comic strip that appeared in the Eagle, 2000 AD and Virgin Comics. In the 1950s, roughly every other story featured the Mekon.

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The Mekon was the ruler of the Treens of northern Venus, although he was ousted from this position at the end of the first story and had no fixed base of operations. He was created by scientific experimentation, engineered for a very high intelligence. As such he had a swollen head containing his massive brain and atrophied body, and moved around on a levitating chair. He typically invented new superweapons in the pursuit of his goal: the domination of the universe for the purpose of scientific research. In some stories he also sought personal revenge on Dan Dare.

The Mekon returns in Virgin Comics Dare miniseries by Garth Ennis, leading a regrouped war fleet with genetically-engineered monsters (based on Treen mythology) and a controlled black hole as a weapon. By issue #3, the Mekon has been almost entirely off-screen, operating remotely, and a source of fear among human & Treen alike. His only appearance was a two-page sequence at the end of #2, where he psychically communed with the British Prime Minister (a servant of his) and showed a detached, dispassionate persona.

Later in the series he attempted to capture Dare, and on doing so ordered him tortured. This proved to be a trap that allowed a group of Royal Marines to attack his ship and soon after a massive naval engagement occurred over Neptune. In the ensuing battle the Mekon's ship was rammed by the HMS Trafalgar and boarded by British troops led by Dare who engaged the Mekon in personal combat before defeating him and leaving him near death. The traitorous prime minister rescued the Mekon and they attempt to escape in a small craft only to be sucked into the Mekon's black hole.

In the final issue of the series, he displays personal hatred for Dare and refers to him as "the Earthman who taught the Mekon how to hate".