Results: 4

daf-36(k114) mutant animals have significantly lower transcript levels of two known targets of DAF-12, mir-84 and mir-241, relative to N2 wild-type (WT) animals, determined by quantitative RT-PCR of L3 stage worms. This reduction is similar to that seen in daf-12(rh61rh411) null mutants (N=3, mean ± SD, *P<0.05, **P<0.005, determined by unpaired t-test).