Peptidyl-tRNA hydrolase (PTH) is a bacterial enzyme that cleaves
peptidyl-tRNA or N-acyl-aminoacyl-tRNA to yield free peptides or N-acyl-amino acids and
tRNA. The natural substrate for this enzyme may be peptidyl-tRNA which drop off the
ribosome during protein synthesis [1833189,
8635758]. Bacterial PTH has been found to be
evolutionary related to a yeast protein [8563640].

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry
out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 2 models
in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical
are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have
different domain combinations including a Peptidyl-tRNA hydrolase-like domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

There are 2 hidden Markov models representing the Peptidyl-tRNA hydrolase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.