ISSA JOKE: The Best 21 Savage Memes

Looking back on the many memes 21 has inspired since he clarified "ISSA KNIFE."

Earlier today, 21 Savage officially deemed himself the inventor of the word "ISSA," writing on Twitter, "it's the most used new word of 2017! we're is my recognition?" Of course, 21 is referring to his 2016 Vlad TV interview, in which he answered an inquiry about his "cross" tattoo with the loudest "well, actually" of the year, "ISSA KNIFE."

I made a new word "ISSA" and it's the most used new word of 2017! we're is my recognition ?😂

"ISSA" has popped up in many memes since the rapper uttered the word, and we've gone back to highlight some of the best jokes that used both the classic interview clip and 21 in general as inspiration. Check them out below.