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Prof. Sir Andrew J MCMICHAELMember of the Scientific Advisory Board

Sir Andrew J MCMICHAEL is a Professor of Molecular Medicine at the Nuffield Department of Medicine at the University of Oxford, UK. He worked for more than 40 years on cytotoxic T-lymphocytes (CTL) responses against viruses, especially influenza

He first showed that human cytotoxic T lymphocyte (CTL) responses to influenza virus were HLA restricted and that these T cells could protect against disease (1977)

Identified the first epitopes seen by CTL in HIV-1 and then show that virus could escape from CTL by mutation, and later showed that this happens with all epitopes, undermining T cell control of the infection with Alain Townsend (1986)

Introduced HLA tetramers into the study of human infections, with Mark Davis and John Altman (1996)

Discovered CD1, with Cesar Milstein

Identified the ligand for the NK cell receptor NKG2/CD94 as a specific peptide bound HLA-E with Veronique Broad