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Cleargenix There are some creams that only reduce the puffiness or dark circles around the eyes. you must read what a cream promises to do before you buy it. For example, you can buy Institut Esthederm products in USA which are known for quality and affordable prices. The sad truth is applying a collagen cream to your skin won't do more than moisturize it for a short period of time. While that is a major concern, free radicals also contribute to premature aging of the skin.