Properties: Tri-vitacid combines three factors of vitamin B complex: B1 , B6 and B12 which are essential for performance of normal metabolism and for proper functioning of the living cells. Vitamin B1 (thiamine) forms the coenzyme cocarboxylase which has an important role in carbohydrate metabolism. It catalyses the decarboxylation of pyruvic acid and other ketoacids. Vitamin B6 (pyridoxine) acts as a coenzyme in protein, fat and carbohydrate metabolism as well as haemoglobin synthesis. It has an important role in decarboxylation, deamination, transamination and transufuration of amino acids. Vitamin B12 (Cyanocobalamine) is essential to growth, cell reproduction, hematopoiesis, and nucleoprotein and myelin synthesis so its deficiency results in neurologic damage. In addition, Vitamin B12 is associated with fat and carbohydrate metabolism and protein synthesis and has the main role in folic acid activation. In addition, Tri-vitacid tablets contain folic acid which is required for nucleoprotein synthesis and maintainance of normal erythropoiesis. It stimulates specifically the production of RBCs, WBCs, and platelets in persons suffering from certain megaloblastic anemia.

Indications and usage: Treatment of vitamin B or folic acid deficiency states which may include:- Beriberi: due to vitamin B1 deficiency which may be related to cardiovascular or nervous system. Vitamin B6 deficiency either due to inadequate diet or isoniazid therapy or use of oral contraceptives. Sideroblastic anemia (idiopathic, acquired or hereditary). Megaloblastic anemia. Pernicious anemia (uncomplicated or accompanied by nervous system involvement). Neuromuscular disorders as tremors and cramps. Diabetic polyneuropathy, acute and chronic neuritis, optic neuritis, and other states related to neurologic damage. Treatment of neuritis of pregnancy Treatment of nausea and vomiting of pregnancy. As vitamin supplement in certain states that need vitamins in excess of normal as (pregnancy, thyrotoxicosis, hemolytic anemia, hemorrhage, malignancy, hepatic and renal disease). Prophylactically after partial or total gastroctomy or total ileal resection.

Contra-indications: Known hypersensitivity to any component of the preparation.

Warning & precautions: Tri-vitacid ampoules is not for I.V. administration.

Dosage and administration: Dosage should be adapted to individual patients. Ampoules: The content of ampoule (A) and (B) are mixed and administered I.M. daily or every other day. Then once or twice weekly.