Ontology

Ontology is the science of the analysis of the features belonging to things simply because of their nature. It puts the focal point on things' nature and structure, without considering anything else. [1]

Gene Ontology (GO) is the leading bioinformatics initiative trying to standardize the representation of gene and gene product characteristics throughout species and databases. They offer many tools to access and process their data and vocabulary terms describing gene product attributes, such as the AmiGO browser.

Biological, Cellular and molecular Functions

The broad biological function of the coagulation Factor VIII is clearly involved in coagulation as seen in Figure 1 above. Figure 2 goes way more in depth by breaking down the cellular component of Factor VIII during coagulation. Cellularly, the Factor VIII gene normally codes for the function of the platelet's alpha-granule's lumen. In other words, the lumen is "the volume enclosed by the membrane of the platelet alpha granule." [2] Going even deeper, we see in Figure 3 that the molecular function of the Factor VIII gene more precisely codes for a copper-ion binding substance.