If they can tour with Mastodon, I'd say it isn't entirely out of the question. I feel like the people that are listening to Manson or Zombie at least know who these guys are, and would probably like them, even if just for the theatrics.

I have no idea how Ghost draws elsewhere, but when they hit San Antonio, they were in a club that houses 1,200 people and it wasn't really packed for Ghost, hence the "good draw" question.