Madison, Erin
2014-09-18T18:07:37Z
2014-09-18T18:07:37Z
2014-03
http://hdl.handle.net/1794/18271
54 pages. A thesis presented to the Department of Human physiology and the Clark Honors College of the University of Oregon in partial fulfillment of the requirements for degree of Bachelor of Arts, Spring 2014.
This project is the first attempt to determine whether the menstrual cycle
hormones have an effect on female blood vessel function as measured by two
recently proposed tests of vessel reactivity. The larger implications of this study
will impact future clinical research, in terms of subject preparation. Specifically, if
it is found that young, healthy, naturally menstruating female subjects' blood
vessel reactivity is affected by the cyclical fluctuation of the hormones estrogen
and progesterone, then future research using these two new techniques should
study female subjects according to the findings of this project. Namely, subjects
should be studied during the menstrual cycle phase that elicits the lowest overall
response when compared to the two other menstrual cycle phases observed, as
this is indicative of the lowest augmentation of the results by the effect of the
hormones. This is important because it is necessary to control for as many
variables as possible in order to ensure confidence in the results of a study. Blood vessel function in this study will be assessed using three techniques
that monitor changes in blood flow and diameter by way of ultrasound imaging.
Using ultrasound, a blood vessel’s resting diameter can be quantified, and then a
test can be performed in order to quantify the effect of that test of the size of the
blood vessel. The amount a blood vessel “dilates,” or increases in size, is a
measure of the health of the blood vessel; in general, the larger the percent change
in size, the healthier the blood vessel is. The female hormones have been shown to
improve blood vessel dilation when assessed by a long-used technique known as
“flow-mediated dilation,” but it has not yet been determined whether other tests
of vessel function, such as a hand grip model or a passive limb movement model,
are similarly affected. Thus, this study seeks to determine the relationship
between these hormones and these three tests of vessel function, using flow mediated
dilation as a barometer for the results observed.
en_US
University of Oregon
University of Oregon thesis, Dept. of Human Physiology, Honors College, B.A., 2014;
All Rights Reserved.
Cardiovascular Physiology
Endothelial Function
Menstrual Cycle
Hormones
Flow-mediated Dilation
Estrogen and Progesterone
Endothelial function across the menstrual cycle as assessed in naturally cycling women by three relevant techniques
Thesis / Dissertation

Rempel, Alexandra
Rempel, Alan
Broberg, Kate Liddle
DiGregorio, Rachelle
Madison, Erin
Hawkins, Lauren
2012-02-06T22:45:35Z
2012-02-06T22:45:35Z
2011-12
http://hdl.handle.net/1794/11935
Website produced for HC 441: Science Colloquium: Energy in Transition, Robert D. Clark Honors College, University of Oregon, Fall Term 2011.
Through an investigation of plastic and aluminum production and recycling, waste to energy methods, plastic bottle use, and plastic bag use, we have come to the conclusion that the citizens and government of the United States need to work together to reduce primary material production and use.
Additionally, we must increase recycling and reuse in order to close the production and consumption loop of potentially hazardous and energy-consuming products, primarily plastic and metals. Through these methods, we can best retain the embodied energy of waste materials and avoid excessive use of non-renewable resources.
en_US
University of Oregon, Clark Honors College
rights_reserved
Recycling (Waste, etc.)
Materials in Transition
Website