Pop superstar Madonna infuriated fans in Colorado on Thursday night when she brandished a gun during her concert, three months after the state was rocked by a deadly cinema massacre.

A dozen people were murdered and another 58 injured when accused gunman James Holmes allegedly opened fire in a crowded midnight screening of The Dark Knight Rises in Aurora on July 20.

The Material Girl took her MDNA tour to the Pepsi Center in Denver this week, but refused to censor her performance in light of the tragedy, and whipped out a pistol during her set, as she has done in all of her previous shows.

The stunt angered many audience members, and several locals even called in to NBC TV station 9News to express their disdain at her use of the gun prop, particularly in the wake of the area's recent history.

Madonna has previously defended the controversial decision to use fake weapons during her stage spectacular, saying, "It's true there is a lot of violence in the beginning of the show and sometimes the use of fake guns - but they are used as metaphors. I do not condone violence or the use of guns."