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Full information about Fanapt

General Information on Fanapt

Fanapt is used for the treatment of schizophrenia in adults. Iloperidone, the main active ingredient in the drug, belongs to a class of medications known as Piperidinyl-benzisoxazole antipsychotics.

Chemicals such as serotonin and dopamine exist in higher amounts in people with schizophrenia. Iloperidone works to inhibit the action of such chemicals and decrease their effects.

Fanapt is available in the form of a tablet. It is available in different strengths such as 1mg, 2mg, 4mg, 6mg, 8mg, 10mg, and 12mg. The drug is a prescription medication, which means you cannot buy Fanapt unless it is prescribed by your doctor.

Side effects of Fanapt

Some schizophrenia patients may experience mild to severe side effects after taking a dose of Fanapt. Dry mouth, weight gain, nausea, stuffy nose, diarrhea, drowsiness, or dizziness are some common side effects associated with the drug. These side effects generally wane over time. However, if they persist or worsen, you must consult your doctor immediately.

In rare cases, Fanapt may cause severe side effects in some schizophrenia patients. Confusion, involuntary movements of the tongue, lips, arms, legs or eyes, stiff muscles, feeling like passing out, high fever, and fast/uneven heartbeat are some severe side effects associated with Fanapt. Stop the medication and consult your doctor immediately if you notice or experience any severe side effects after taking a dose.

Fanapt may also cause hyperglycemia (high blood sugar), which can be identified by signs such as excessive hunger, increased urination or thirst, and weakness. Diabetic patients should take regular blood tests during treatment. It is not necessary that every person using this drug will experience some side effect. Many people using Fanapt do not complain about any side effects.

Dosage of Fanapt

Your doctor will give you specific instructions regarding the dosage. The treatment generally starts with a small dose, which is increased gradually during treatment. The recommended dose on the 1st day of treatment is one Fanapt 1mg tablet twice a day. Your doctor will ask you to take 2mg, 4mg, 6mg, 8mg, 10mg, and 12mg Fanapt tablets twice daily on the 2nd, 3rd, 4th, 5th, 6th and 7th day respectively. Doctors generally determine the effective dose of Fanapt via the titration method.

The maximum recommended dose of Fanapt is 12mg twice daily. The dosage is adjusted for schizophrenia patients who are also taking drugs that are powerful CYP2D6 inhibitors. You can take Fanapt with or without food. Do not use Fanapt in larger amounts or for a longer period than prescribed by your doctor.

Interactions

Fanapt may potentially interact with other drugs you are using and cause side effects. It may interact with specific antibiotics, antimalarial medicines, antidepressants, heart rhythm medications, arsenic trioxide, narcotic medications, drugs used to treat psychiatric disorders, medications used to treat nausea and vomiting, Droperidol, and migraine headache medicines.

To reduce the risk of side effects, inform your doctor about every drug you are using before you buy Fanapt, including prescription drugs, herbal supplements, and over the counter drugs.

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What is a "Generic" medication/drug?

Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:

Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)

Dosage (e.g. 10 mg of the active ingredient)

Safety (e.g. same or similar side effects, drug interactions)

Strength

Quality

Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)

Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)

What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.

What differences are there between generic and brand?

While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:

Color

Shape

Size

Cost

Appearance (e.g. the scoring or markings)

The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.

Why do generics cost less than the brand name equivalents?

When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.

The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.

How are Generic drugs tested to ensure quality and efficacy?

The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.