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Pietz was born in Milwaukee, Wisconsin, the adopted daughter of Nancy, a nurse, and Arnold Pietz, a truck driver. She trained throughout her childhood in ballet and prepared to go professional, but eventually decided against it due to the low pay and shifted her focus elsewhere.[1] She attended The Milwaukee High School of the Arts and graduated from The Theatre School at DePaul University.

In 2011, Pietz played Meredith King, the mother of Chloe King, in the short-lived ABC Family drama series The Nine Lives of Chloe King.[6] In 2016, she was cast as lead character's boss in The CW comedy-drama series No Tomorrow.[7]

In 2016, Pietz guest-starred in the 4th season of Marc Maron's IFC series Maron as Natalie, a fellow rehab patient.

Pietz married actor Kenneth Alan Williams in 1997 in her native Milwaukee. They have since divorced.[1] Pietz gave birth to a son when she was 23, Benjamin, whom she subsequently gave up for adoption.[8][9]