sulfone sul·fone (sŭl'fōn')n. Any of various organic sulfur compounds having a sulfonyl group attached to two carbon atoms, especially such a compound formerly used as a drug to treat leprosy or tuberculosis.

(sŭl'fōn') Any of various organic sulfur compounds having a sulfonyl group (SO2) attached to two carbon atoms. Sulfones were formerly used to treat leprosy and tuberculosis, and are now used in making synthetic resins for wire coatings, automotive parts, and plumbing items.