Last fall, a team based mainly at Brigham & Women’s Hospital won a nearly $10-million grant to determine how whole-genome sequencing can be used in the clinic. I asked Dr. Isaac Kohane, the team’s co-director among other titles, to help us imagine what it will look like in practice when a doctor has a patient’s full set of DNA in hand. He kindly collaborated on the script and voicing of the 5-minute cartoon video above.