Effects of MGB on Type 2 Diabetes in Lower BMI Patients

Abstract

The Mini-gastric bypass (MGB) has resulted in significant weight loss and resolution of type 2 diabetes (T2D). The current indication for bariatric surgery is mainly for patients with BMI >35 with co-morbidities. However, success is being reported with MGB for T2D with BMI <35. Evidence suggests that bypass of the duodenum may provide superiority of MGB over sleeve gastrectomy (SG) and even over Roux-en-Y gastric bypass (RYGB) for T2D remission. MGB and RYGB have similar mechanisms of T2D remission, but being easier to perform, MGB may be the superior option.

MGB is being found to provide good long-term control of T2D with BMI <35, and earlier intervention appears to yield better results. Due to its low complication rate, MGB may be considered for T2D patients even with class I obesity. However, it appears that the lower the BMI, the less responsive T2D is to bariatric surgery. However, the resolution after MGB and OAGB has shown durable results, including after BMI <35.

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