“Big number of chances and a wonderful goalkeeper from Tottenham (Michel Vorm). All good. I think it was entertaining.

“He (Sturridge) did what he has to do and it was brilliant. He could have scored three or maybe four, but it was really good. That’s his big strength and he showed it again.”

Klopp and Spurs counterpart Mauricio Pochettino between them made 21 changes to their starting line-ups, with visiting midfielder Eric Dier the only player to keep his place from the weekend fixtures.

Klopp gave a debut to 18-year-old right-back Trent Alexander-Arnold and a full debut to midfielder Ovie Ejaria, 19, while 18-year-old Cameron Carter-Vickers started at centre-back for Tottenham.

Liverpool, who lost on penalties to Manchester City in last season’s final, took a ninth-minute lead when Marko Grujic’s deflected cross from the right was stabbed in by Sturridge.

Spurs stand-in goalkeeper Vorm repelled long-range efforts from Sturridge and Divock Origi before Georginio Wijnaldum freed the England striker to score his second goal in the 64th minute.

Dutch striker Vincent Janssen reduced the arrears with a 76th-minute penalty after Lucas Leiva took an unnecessary nibble at Tottenham substitute Erik Lamela.

Newcastle cruise

But it was the home side who came closest to scoring again, with Vorm saving spectacularly from Sturridge and substitute Danny Ings.

“I’m pleased with the performance, but not the result. We fought until the end and created chances,” said Spurs manager Pochettino.

“It was a great experience and we can take a lot of positives.”

Arsenal joined Klopp’s men in the last eight after seeing off second-tier Reading, who are managed by former Manchester United defender Jaap Stam.

Oxlade-Chamberlain struck twice for Arsene Wenger’s much-changed team, drilling home in the 33rd minute and netting again with the aid of a deflection with 12 minutes to play.

Headers from centre-backs Harry Maguire and Michael Dawson took Hull through at the expense of Bristol City, who replied through Lee Tomlin’s 50-yard solo goal in stoppage time.

Aleksandar Mitrovic and Mohamed Diame each scored twice as Championship leaders Newcastle United routed 10-man Preston North End 6-0 at St James’ Park.

Leeds United twice came from behind and survived playing extra time with 10 men, after making all their substitutions and losing a player to injury, to edge Norwich City 3-2 on penalties following a 2-2 draw.

The tie of the round takes place on Wednesday, when Jose Mourinho and Pep Guardiola resume hostilities as Manchester United tackle Manchester City at Old Trafford.

Chelsea visit London rivals West Ham United and Southampton host the Premier League’s bottom club, Sunderland.