Renal Dose Adjustments

Liver Dose Adjustments

Precautions

Dialysis

Data not available for dextromethorphan and guaifenesin
Pseudoephedrine is slightly dialyzable; however, no dose adjustment guidelines have been reported.

Other Comments

General: The FDA has not approved use of over-the-counter cough and cold medications to children aged less than 2 years, and proper dosing for children in this age group has not been studied. Clinicians should be aware of the risk for serious illness or fatal overdose from administration of cough and cold medications to children aged less than 2 years. Clinicians should be certain that caregivers understand 1) the importance of administering cough and cold medications only as directed and 2) the risk for overdose if they administer additional medications that might contain the same ingredient.

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