No one has ever insulted a president to his face quite like comedian Zach Galifianakis.

President Obama appeared on the wonderfully awkward "Between Two Ferns" web series Tuesday, and for every insult Galifianakis threw his way, the president gave it right back.

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"I read somewhere that you'd be sending Hulk Hogan to Syria," Galifianakis said, after bringing up "Ambassador" Dennis Rodman's recent trips to North Korea, which Galifianakis called "North Ikea." "What's it like to be the last black president?"

Obama responded, "Seriously? What's it like for this to be the last time you ever talk to a president?"

"It must kind of stink, though, that you can't run (for office) three times," Galifianakis said.

Obama came back with probably the interview's best line: "If I ran for a third time, it'd be sort of like doing a third 'Hangover' movie. Didn't really work out very well, did it?"

Obama was appearing on the show to urge young people to get on board with his health care plan. But, clearly, that was secondary to the deadpan verbal jousting.

"I have to say, when I heard that people actually watch this show, I was actually surprised," Obama said to Galifianakis, who then started asking about pardoning turkeys, birth certificates and Kenya. Obama didn't even blink.

"We'll probably pardon another turkey. We do that every Thanksgiving. Was that depressing to you -- seeing one turkey taken out of circulation, a turkey you couldn't eat?" Obama said.

In this Sunday, May 12, 2013 photo, actor Zach Galifianakis, of the film, "The Hangover Part III," poses at Caesars Palace in Las Vegas. (Photo by Eric Jamison/Invision/AP)

Obama also mentioned how much he enjoyed seeing Galifianakis' "The Hangover" castmate Bradley Cooper on the show.

"Bradley Cooper ..." mumbled Galifianakis under his breath. "Everybody loves Bradley. Being like that in Hollywood, that's easy. Be short, fat, and smell like Doritos and try to make it in Hollywood."

The president replied, "He kind of carried that movie, didn't he?"

Galifianakis also asked about the president saying if he had a son, he would not let him play football. "What makes you think he would want to play football?" the comedian said. "What if he was nerd like you?

"Do you think a woman like Michelle would marry a nerd?" the president responded.