Michael Duggan <michael.duggan at camr.org.uk> wrote:
:: We want to measure glutamate release from cultured dorsal root
: ganglion neurons. We have had some tries with radiolabelled D-Asp
: and glutamine labelling of the cells, but the results are not as good
: as we would like them to be (variability in loading, lack of calcium
: dependence for release etc.).
I was just passing through.
I have seen several studies of the anticonvulsants lamotrigine (Lamictal)
and gabapentin (Neurontin) that assayed glutamate release. Perhaps
you could find them on Medline and contact the authors.
- Scott