The overly-discharched neuro-endocrine system then lacks much of its rejuvenating / restorative potential, resulting in a vicious cycle of inflammation and a negative neuroplasticity. Abundant inflammatory byproducts then lead to nervous cells toxicity, affecting numerous systems, organs, tissues, and one’s hypothalamic-pituitary-adrenal-testicular axis for either lowered androgens or PSAS if prolactin remains relatively low (frequently but not always as a result of harmful practices like edging).

The production of vital androgens, such as: DHEA, testosterone, androstenedione, and DHT, plus some additional neurotransmitters like oxytocin and Nitric Oxide becomes too low to support neuro-modulatory and immune functions responsible for prostaglandin E2, cortisol, histamine, glutamate regulation.

One’s hypothalamic – pituitary – adrenal – testicular axis will be disabled for a few days, weeks, or even months by inflammatory / excitatory cortisol, prolactin, norepinephrine, epinephrine. The refraction time will be lengthened leading to a chronic sexual exhaustion and a self supporting cycle of inflammation. As a result, excitotoxicity is observed in brain cells, heart, liver, kidneys, blood vessels, digestive system, prostate, pancrease, gallbladder, testicles, eyes, skin, bones, joints, and numerous soft tissues.

Ejaculation will spend much of the vital chemicals found in semen, as it is rich in: androgen hormones, free amino acids, zinc, calcium, magnesium, potassium, fructose, prostaglandins E1 E3, and numerous supporting enzymes.

Excessive pro-inflammatory responses to dopamine – norepinephrine – epinephrine conversions are frequently observed during sexual activities. Similar occurrences result in additionally lowered androgens and neurotransmitters for days or even weeks after.

The mentioned suppression of androgen hormones will only get worse if one continues engaging in over active sexual activities. Artery constriction in the brain, adrenal glands, liver, and testicles will spread to even larger blood vessels for a chronic fatigue and shortness of breath.

As a result of the above, Sexual Exhaustion will cause numerous symptoms depending on individual genotype and gene expressions.

Ear Buzzing and Ringing – due to shrinkage of the sound reception pathway through excessive epinephrine, shape alterations caused by deficiency of neurotransmitters and vital androgens, and numerous internal inflammatory processed to impact the tympanic membrane cavity and cochlea.

Ejaculatory and Low Back Pains – due to lack of sufficient prostaglandin E1 E3 for tissue elasticity, low androgens, artery narrowness, and local tissue inflammation.

Penile Shrinkage – as a result of lowered androgens for spongy tissue atrophy, decreased prostaglandin E1 E3 and Nitric Oxide for lowered tissue elasticity, and a chronic artery constriction and inflammation.

Prostatitis – as a result of excessive inflammatory processes, low grade semen abrading the local tissues upon ejaculation, and excessive testosterone – DHT conversions.