The study analysed that the Herpes simplex virus infections pipeline comprises of 20 drug candidates, of which one drug candidate is in Phase III stage, five drug candidates are in Phase II stage, three drug candidates are in Phase I stage, eight drug candidates are in Pre-Clinical stage, three candidates are in discovery Phase. Herpes is an infection caused by a virus known as, herpes simplex virus. It is estimated that around 3.7 billion people under the age of 50 years are suffering with the herpes simplex virus infection, globally. The disease is categorized into two types: HSV1 and HSV2. HSV1, also known as oral herpes can lead to sores on the mouth and around the lips. HSV2 causes genital herpes, and is a sexually-transmitted virus which is a leading cause of recurrent genital herpes worldwide. Various new therapies and advanced technologies are driving the growth of Herpes simplex virus infections pipeline.

Insights on pipeline segments

As per the findings of the research, around 20.0% of drug candidates for the treatment of Herpes simplex virus infections Therapeutic pipeline are being developed to be administered by oral route,15.0% by intravenous route, 40.0% are not disclosed and 25.0% are to be administered by other routes which includes sublingual, intramuscular and Topical.

New innovating technologies offer development of promising drugs

Many technologies are being developed that offer promising innovative treatments which can control the progression of Herpes simplex virus infections such as, Vector based technology platform, AdenoVerse technology platform, Juvari’s technology platform and Nanostat technology platform. AdenoVerse technology platform includes a broad range of adenovirus vectors for efficient gene delivery for therapeutics and vaccines as well as proven scale-up and production methodologies and proprietary manufacturing cell lines. All these technologies are important for developing of drugs for the treatment of Herpes simplex virus infections.

Major companies collaborate for the development of Herpes simplex virus infections Pipeline

The research also found that various companies have collaborated for the development of Herpes simplex virus infections pipeline. In July 2013, NanoBio Corporation entered into an agreement with the Division of Microbiology and Infectious Diseases (DMID), a division of National Institute of Health. Under the agreement, DMID agreed to fund certain activities and studies in support of developing intranasal and intramuscular nanoemulsion vaccines for HSV-2. In June 2014, – PaxVax Inc., entered into a research and development collaboration with the University of California to develop a combination vaccine to prevent genital herpes simplex virus infections.

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