Partial response class-IV signaling combined with Viterbi decoding to perform maximum-likelihood sequence detection is considered for high-speed data transmission over twisted-pair cables. In order to establish which data rates and distances can be achieved by this method, a performance evaluation is conducted. Binary and quaternary modulations are considered, and disturbance of the received signal by near-end and far-end crosstalk and additive white Gaussian noise is taken into account. A benchmark comparison with rigorously optimized symbol-by-symbol detection systems using AMI and HDB3 line coding is presented