Jun. 15, Vol. 33, No. 12

Point of View

“Genome 2.0? Aren’t we on, like, Genome 1,000 by now?”
Yes, we are. In fact, more than 4,300 different whole genomes have been sequenced, nearly 200 of which are eukaryotic. Moreover, with targeted exome resequencing included, many more thousands
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Feature Articles

Tiny, subcellular membrane-bound vesicles called exosomes are periodically released by a wide variety of cell types, carrying along with them proteins, microRNA (miRNA), and mRNA fragments representative of their cells of origin.
It is thought tha
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Whether it’s dispensing reagents, washing plates, or plating out bacteria, moving things around is at the core of biomedical R&D and production.
The task is increasingly done in high-throughput using robotics and automation, which take care of
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Biotechnology primarily focuses on creating novel biologic therapeutics, and there’s no doubt that bioresearch has led to a number of life-improving and life-saving drugs. Indeed, last fall the European Medicines Agency approved the first gene thera
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Overcoming toxicity and poor accumulation are common themes in many unsuccessful attempts to overexpress difficult proteins such as multispanning membrane proteins.
According to Genentech’s Hok Seon Kim, Ph.D., senior research associate in antibod
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Rooted in mythology, legends, and folklore, the prospect of re-growing body parts has fascinated humanity since ancient times. One mythical creature from ancient Greece, the nine-headed Hydra, was able to grow two heads in place of one.
And Promet
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Tutorials

A common solution for producing higher quantities of anchorage-dependent cells has been to use large numbers of roller bottles and multi-trays to simply multiply the number of static surface areas.
The main disadvantage of this approach is that th
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Cultivating cells may take days to weeks, making it difficult to monitor morphological changes. The long-term time-lapse monitoring of cells can provide reliable data about cell growth and death, and morphological changes. Cell proliferation and dea
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The purification of cellular populations and individual cells is pivotal for the reliable characterization of gene expression, many aspects of life science research, and the development of cellular therapies. Cell sorting routinely involves fluoresc
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Corporate Profile

NanoSight had already established itself as a top-tier maker of nanoparticle detection machines three years ago when a group of researchers from the University of Oxford persuaded the company to think even smaller.
The group had been using flow cy
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BioMarket Trends

Some 120 investigators and other experts in chronic myeloid leukemia (CML) from 15 countries revisited a sore topic within the biopharma industry recently when they decried the high price of drugs for CML, and by extension, treatments for all cancer
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Application Note

The Pf enex Expression Technology™ platform is a very powerful protein expression technology based on the microorganism Pseudomonas fluorescens . The Pfenex platform technology can deliver a robust production strain with unprecedented speed and a su
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ANNOVAR® (1) provides flexibility to handle and analyze variant datasets of genomic scale. Here we make use of ANNOVAR®’s capabilities to understand a breast cancer variant dataset by applying its variant reduction functionality, combined
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While the traditional cloning workflow has been used in laboratories for decades, new techniques have emerged that allow for rapid assembly of multiple genetic fragments. The Electra Vector System, developed by DNA2.0, is a universal cloning system
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Tech Notes

Chemical analysis is a critical need in our high-tech industrial world. Mass spectrometry, with its high sensitivity and high selectivity, occupies a pivotal role in the detection and quantitation of a vast array of chemical substances. It is the ap
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Jobs

GEN Jobs powered by HireLifeScience.com connects you directly to employers in pharma, biotech, and the life sciences. View 40 to 50 fresh job postings daily or search for employment opportunities including those in R&D, clinical research, QA/QC, biomanufacturing, and regulatory affairs.

GEN Poll

Secure Science

Should bans on science education, of the sort imposed on Iranians hoping to study physics and engineering in the United States, encompass other nationals and other fields of study, including biotechnology?

No. Such bans could easily get out of control, preventing the sharing and growth of knowledge.

Yes. The potential, for example, for the development of bioweapons if biotech information gets into the wrong hands must be minimized.

No. Such bans could easily get out of control, preventing the sharing and growth of knowledge.

56.6%

Yes. The potential, for example, for the development of bioweapons if biotech information gets into the wrong hands must be minimized.

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