SPs have to work with the tactic, so there is no guarantee that they will work the same with a 4141 as thy do with a 442. The latest tactics with SP in name are latest SPs that you can copy, but I use a few corner set ups both attacking and defending.

Takers are either set up or I leave it blank. SPs have to work with tactic but I am trying various different options as the game is overriding the set up, which can leave one on ones or no player as the short option.

I test other roles, but it is often a combination that works and that has to be done playing games. Also I do not use a test league that controls variables. If you can set up a test league like that, and have a powerful computer you could test many combinations.

In essence you are looking for the best talent for these positions (with Genie you can use CA/PA and positional ratings on right hand side) You can adjust positional ratings for your own Club DNA, and would be a useful tool to have in game)
GK
WBs (more attacking orientated than FBs)
CDs
WBs
MC D can be a DM/MC
MC A can be MC/AP
FS
Screenshot of how Genie shows positions.
Because Genie shows CA PA if you need more info on Genie best to PM me.

There should be at least 1 WB staying back and a designated corner taker. It appears that these instructions are being ignored by the ME. (Set Pieces in general are a mess).
I would check which players in squad are being allocated to take corners or allocate your best corner taker and then change the corner set up to reflect choice.