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Biography

Dr. O’Brien’s clinical and research interests include pediatric thrombosis and thromboprophylaxis, the evaluation and diagnosis of mild bleeding disorders, and the intersections between hematology and women’s health. She also leads a multidisciplinary hematology and adolescent gynecology clinic at Nationwide Children’s. As a health services researcher, Dr. O’Brien has a
particular interest in the use of large administrative databases, as well as decision analysis and cost effectiveness analysis.
She attended the University of Pittsburgh School of Medicine and received her residency and fellowship training from
Children’s Hospital of Pittsburgh of UPMC. Dr. O’Brien is voted among the “Best Doctors in America”.

Research Funding*:

4-week, open label, multiple-dose study of the safety and the pharmacokinetic and pharmacodynamic properties of the oral direct factor Xa inhibitor rivroxaban in pediatric subjects with venous thromboembolism

Candrilli,S,D; Davis,K,L; Balkrishnan,R; O'Brien,S. 2009. CHANGES IN RATES OF SICKLE CELL DISEASE-RELATED INPATIENT STAYS AND ASSOCIATED RESOURCE USE AMONG AFRICAN AMERICANS IN THE UNITED STATES FOLLOWING APPROVAL OF HYDROXYUREA.

Candrilli,Sean,D; Balkrishnan,Rajesh; O'Brien,Sarah,H. 2009. Effect of injury severity on the incidence and utilization-related outcomes of venous thromboembolism in pediatric trauma inpatients. In 13th Annual International Meeting of the International-Society-of-Pharmacoeconomics-and-Outcomes-Research

Candrilli,Sean,D; Balkrishnan,Rajesh; O'Brien,Sarah,H. 2009. Effect of injury severity on the incidence and utilization-related outcomes of venous thromboembolism in pediatric trauma inpatients. In 13th Annual International Meeting of the International-Society-of-Pharmacoeconomics-and-Outcomes-Research

O'Brien,Sarah,H; Smith,Kenneth,J. 2009. Using Thrombophilia Testing to Determine Anticoagulation Duration in Pediatric Thrombosis is not Cost-Effective. In 49th Annual Meeting of the American-Society-of-Hematology

Candrilli,S,D; Balkrishnan,R; O'Brien,S. 2008. The effect of injury severity on the incidence and resource utilization-related outcomes of deep vein thrombosis among pediatric trauma admissions in the United States.