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J&J to Warn on Hismanal's Label
Of Potential Reactions to Drugs

By

Elizabeth Daerr and

Bruce Ingersoll Staff Reporters of The Wall Street Journal

Updated Feb. 10, 1998 12:07 a.m. ET

WASHINGTON -- A Johnson & Johnson unit is changing the labeling on Hismanal, an antihistamine, to warn patients about potentially serious interactions with certain antibiotics, antidepressants and other drugs.

The drug interactions have been linked with irregular heart beats and cardiac arrest as well as rare cases of anaphylactic shock, the Food and Drug Administration said.