A '''hallucination''', in the broadest sense, is a [[perception]] in the absence of a [[stimulus (physiology)|stimulus]]. In a stricter sense, hallucinations are defined as perceptions in a conscious and awake state in the absence of external stimuli which have qualities of real perception, in that they are vivid, substantial, and located in external objective space. These definitions distinguish hallucinations from the related phenomena of [[dream]]ing, which does not involve consciousness; [[illusion]], which involves distorted or misinterpreted real perception; [[imagery]], which does not mimic real perception and is under voluntary control; and [[pseudohallucination]], which does not mimic real perception, but is not under voluntary control.<ref name="Chiu">{{citejournal

+

{{Infoboxdisease

+

| Name = Hallucination

+

| Image = August_Natterer_Meine_Augen_zur_Zeit_der_Erscheinungen.jpg

+

| Caption = ''My eyes at the moment of the apparitions'' by [[August Natterer]], a German artist who created many drawings of his hallucinations.

+

| DiseasesDB = 19769

+

| ICD10 = {{ICD10|R|44||r|40}}

+

| ICD9 = {{ICD9|780.1}}

+

| ICDO =

+

| OMIM =

+

| MedlinePlus = 003258

+

| eMedicineSubj =

+

| eMedicineTopic =

+

| MeshID = D006212

+

}}

+

+

A '''hallucination''' is a [[perception]] in the absence of apparent [[stimulus (physiology)|stimulus]] which has qualities of real perception. Hallucinations are vivid, substantial, and located in external objective space. They are distinguished from the related phenomena of [[dream]]ing, which does not involve wakefulness; [[illusion]], which involves distorted or misinterpreted real perception; [[mental imagery|imagery]], which does not mimic real perception and is under voluntary control; and [[pseudohallucination]], which does not mimic real perception, but is not under voluntary control.<ref name="Chiu">{{cite journal

| author = Leo P. W. Chiu

| author = Leo P. W. Chiu

| year = 1989

| year = 1989

Line 8:

Line 8:

| volume = 41

| volume = 41

| issue = 3

| issue = 3

−

| pages = 292–297

+

| pages = 292–7

| doi =

| doi =

| url = http://sunzi1.lib.hku.hk/hkjo/view/21/2100448.pdf

| url = http://sunzi1.lib.hku.hk/hkjo/view/21/2100448.pdf

−

}}</ref>

+

|format=PDF}}</ref>

−

Hallucinations also differ from "delusional perceptions", in which a correctly sensed and interpreted genuine perception is given some additional (and typically bizarre) significance.

+

Hallucinations also differ from "[[delusion]]al perceptions", in which a correctly sensed and interpreted stimulus (i.e. a real perception) is given some additional (and typically bizarre) significance.

A mild form of hallucination is known as a disturbance, and can occur in any of the senses above. These may be things like seeing movement in [[peripheral vision]], or hearing faint noises and voices.

+

A mild form of hallucination is known as a ''disturbance'', and can occur in any of the senses above. These may be things like seeing movement in [[peripheral vision]], or hearing faint noises and/or voices.

+

Auditory hallucinations are very common in paranoid schizophrenia. They may be benevolent (telling the patient good things about themselves) or malicious, cursing the patient etc. Auditory hallucinations of the malicious type are frequently heard like people talking about the patient behind their back. Like auditory hallucinations, the source of their visual counterpart can also be behind the patient's back. Their visual counterpart is the feeling of being looked-stared at, usually with malicious intent. Frequently, auditory hallucinations and their visual counterpart are experienced by the patient together.

−

[[Hypnagogic hallucination]]s and [[hypnopompia|hypnopompic hallucination]]s are considered normal phenomena. Hypnagogic hallucinations can occur as one is falling asleep and hypnopompic hallucinations occur when one is waking up. Hallucinations may also be associated with [[Psychoactive drug|drug]] or alcohol use (particularly [[deliriants]]), [[sleep deprivation]], [[psychosis]], [[neurological disorder]]s, and [[delirium tremens]].

+

[[Hypnagogic hallucination]]s and [[hypnopompia|hypnopompic hallucination]]s are considered normal phenomena. Hypnagogic hallucinations can occur as one is falling asleep and hypnopompic hallucinations occur when one is waking up.

Studies have shown that hallucinatory experiences take place worldwide. One study from as early as 1894<ref>Sidgwick, H., Johnson, A, Myers, FWH et al (1894) Report on the census of hallucinations. ''Proceedings of the Society for Psychical Research'', 34, 25-394.<br></ref> reported that approximately 10% of the population experienced hallucinations. A 1996-1999 survey of over 13,000 people<ref>[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11166087&dopt=Abstract Ohayon MM. (2000)] Prevalence of hallucinations and their pathological associations in the general population. ''Psychiatry Research'', 97(2-3), 153-64.<br></ref> reported a much higher figure, with almost 39% of people reporting hallucinatory experiences, 27% of which were daytime hallucinations, mostly outside the context of illness or drug use. From this survey, [[olfactory]] (smell) and [[gustatory]] (taste) hallucinations seem the most common in the general population.

+

==Epidemiology==

+

{{Main|Epidemiology of hallucinations}}

+

One study from as early as 1895<ref>{{cite journal |author=Francis Nagaraya, Myers FWH et al. |title=Report on the census of hallucinations |journal=Proceedings of the Society for Psychical Research |volume=34 |pages=25–394 |year=1894 }}

+

</ref> reported that approximately 10% of the population experienced hallucinations. A 1996-1999 survey of over 13,000 people<ref>{{cite journal |author=Ohayon MM |title=Prevalence of hallucinations and their pathological associations in the general population |journal=Psychiatry Res |volume=97 |issue=2–3 |pages=153–64 |year=2000 |month=Dec |pmid=11166087 |url=http://linkinghub.elsevier.com/retrieve/pii/S0165178100002274 |doi=10.1016/S0165-1781(00)00227-4}}<br></ref> reported a much higher figure, with almost 39% of people reporting hallucinatory experiences, 27% of which were daytime hallucinations, mostly outside the context of illness or drug use. From this survey, [[olfactory]] (smell) and [[gustatory]] (taste) hallucinations seem the most common in the general population.

[[Visual]] hallucination is the 'seeing of things that are not there'<ref name="Visual Hallucination and Illusion Disorders: A Clinical Guide">{{cite web|last=Ffytche|first=Dominic|title=http://www.acnr.co.uk/pdfs/volume4issue2/v4i2reviewart3.pdf|url=http://www.acnr.co.uk/pdfs/volume4issue2/v4i2reviewart3.pdf|accessdate=23 December 2012}}</ref> which can also (according to some definitions) include 'seeing things that are there, incorrectly' ([[Illusion]]s).

−

===[[Auditory hallucinations]]===

+

===Auditory===

−

[[Sound|Auditory]] hallucinations (also known as '''Paracusia'''),<ref>{{cite web | url = http://medical-dictionary.thefreedictionary.com/paracusia | title = Medical dictionary}}</ref>are the perception of sound without outside stimulus. Auditory hallucinations can be divided into two categories: elementary and complex. Elementary hallucinations are the perception of sounds such as hissing, whistling, an extended tone, and more. In many cases, tinnitus is an elementary auditory hallucination. However, some people who experience certain types of tinnitus, especially pulsatile tinnitus, are actually hearing the blood rushing through vessels near the ear, and are frequently misdiagnosed.

+

{{main|Auditoryhallucination}}

−

Complex hallucinations are those of voices, music, or other sounds which may or may not be clear, may be familiar or completely unfamiliar, and friendly or aggressive, among other possibilities. Hallucinations of one or more talking voices, are particularly associated with [[psychosis|psychotic]] disorderssuchas [[schizophrenia]], and hold special significance in diagnosing these conditions. However, many people not suffering from diagnosable [[mental illness]] may sometimes hear voices as well.<ref>{{cite web | url = http://www.livescience.com/humanbiology/060915_hearing_voices.html | title = Hearing Voices: Some People Like It | last = Thompson | first = Andrea | publisher = LiveScience.com | date = [[September 15]], [[2006]]|accessdate = 2006-11-25 }}</ref> Oneimportantexampletoconsiderwhenformingadifferentialdiagnosisforapatientwithparacusiaislateral[[temporal lobeepilepsy]]. Despite the tendencytoassociatehearingvoices, orotherwisehallucinating, and psychosiswithschizophrenia or other psychiatricillnesses, it is crucialtotakeintoconsiderationthatevenifapersondoesexhibitpsychotic features, theydonotnecessarilysufferfromapsychiatricdisorderonitsown.DisorderssuchasWilson'sdisease,variousendocrinologicaldisorders,numerousmetabolicdisturbances, multiplesclerosis,[[systemiclupuserythematosis]],porphyria, sarcoidosis, and many others can present withpsychosis.

Complex hallucinations are thoseofvoices,music,orothersoundswhichmayor may not be clear,maybefamiliarorcompletely unfamiliar, and friendly or aggressive, among other possibilities. Hallucinations of oneormoretalking voices are particularly associated with [[psychosis|psychotic]] disorders such as [[schizophrenia]], and hold special significance in diagnosingtheseconditions. However, manypeoplenotsufferingfromdiagnosable [[mental illness]] may sometimes hear voices as well.<ref>{{citeweb|url=http://www.livescience.com/7177-hearing-voices-people.html|title = Hearing Voices: Some People Like It | last = Thompson | first = Andrea | publisher =LiveScience.com|date = September 15, 2006|accessdate=2006-11-25}}</ref>Oneimportantexampletoconsiderwhenformingadifferential diagnosis for a patientwith paracusia is lateral [[temporal lobe epilepsy]]. Despite the tendency to associate hearing voices, orotherwisehallucinating, and [[psychosis]] with schizophrenia or otherpsychiatricillnesses, itis crucial to take into consideration that even if a person does exhibit psychotic features, theydo not necessarily suffer from a psychiatric disorder on its own. Disorders such as [[Wilson's disease]], various[[endocrinediseases]],numerous[[metabolic disturbances]], [[multiplesclerosis]], [[systemiclupus erythematosis]], [[porphyria]], [[sarcoidosis]], and many others can present withpsychosis.

The [[Hearing Voices Movement]] is a support and advocacy group for people who hallucinate voices, but do not otherwise show signs of mental illness or impairment.

The [[Hearing Voices Movement]] is a support and advocacy group for people who hallucinate voices, but do not otherwise show signs of mental illness or impairment.

−

===[[Gustatoryhallucinations|Olfactory hallucinations]]===

+

High [[caffeine]]consumption has been linked to an increase in the likelihood of experiencing auditory hallucinations. A study conducted by the [[La Trobe University]] School of Psychological Sciences revealed that as few as five cups of coffee a day could trigger the phenomenon.<ref>[http://www.medicalnewstoday.com/articles/227884.php Medical News Today: "Too Much Coffee Can Make You Hear Things That Are Not There"]</ref>

−

[[Phantosmia]]isthephenomenon of smelling [[odor]]s that aren't really present. The most common odors are unpleasant smells such as rotting flesh, vomit, urine, feces, smoke, etc. Phantosmia often results from damage to the [[nervous tissue]] in the [[olfactory]] system. The damage can be caused by [[viral infection]], [[brain tumor]], [[Physical trauma|trauma]], [[surgery]], and possibly exposure to [[toxin]]s or [[drug]]s.<ref>[http://www.doctorhoffman.com/wwphant.htm Phantom smells<!-- Bot generated title -->]</ref> Phantosmia can also be induced by [[epilepsy]], particularly medial [[temporal lobe epilepsy]], because of the excitability of the temporal lobes and the amount of olfactory input received by the [[amygdala]], [[entorhinal cortex]], and piriform cortex. Phantosmia is not the same as [[parosmia]], in which a stimulus is present but the perception and/or interpretation of the smell is distorted.

+

===Commandhallucinations===

+

Command hallucinations are hallucinations in the form of commands; they can be auditory or inside of the persons mind and / or consciousness.<ref name="Beck-Sander1997" /> The contents of the hallucinations can range from the innocuous to commands to cause harm to the self or others.<ref name="Beck-Sander1997">{{cite journal|pmid=9051285|year=1997|last1=Beck-Sander|first1=A|last2=Birchwood|first2=M|last3=Chadwick|first3=P|title=Acting on command hallucinations: A cognitive approach|volume=36 ( Pt 1)|pages=139–48|journal=The British journal of clinical psychology / the British Psychological Society|doi=10.1111/j.2044-8260.1997.tb01237.x}}</ref> Command hallucinations are often associated with [[schizophrenia]]. People experiencing command hallucinations may or may not comply with the hallucinated commands, depending on circumstances. Compliance is more common for non-violent commands.<ref>{{cite journal| pmid=15679207| year=2004| last1=Lee| first1=TM| last2=Chong| first2=SA| last3=Chan| first3=YH| last4=Sathyadevan| first4=G| title=Command hallucinations among Asian patients with schizophrenia| volume=49| issue=12| pages=838–42| journal=Canadian journal of psychiatry. Revue canadienne de psychiatrie}}</ref><br />

+

Command hallucinations are sometimes used in defense of a crime, often homicides. It is essentially a voice one hears and it tells them what to do. Sometimes they are quite benign directives such as "Stand up." or "Shut the door."<ref name="Shea">{{cite web|last=Shea|first=Sean Christopher|title=M.D|url=http://www.suicideassessment.com/tips/archives.php?action=prod&id=64}}</ref> Whether it is a command for something simple or something that is a threat, it is still considered a "command hallucination." Some helpful questions that can assist one in figuring out if they may be suffering from this includes: "What are the voices telling you to do?","When did your voices first start telling you to do things?, "Do you recognize the person who is telling you to harm yourself (others)?", "Do you think you can resist doing what the voices are telling you to do?".<ref name="Shea"/>

−

===[[Proproceptive hallucinations]]===

+

===Olfactory===

+

[[Phantosmia]] is the phenomenon of smelling [[odor]]s that aren't really present. The most common odors are unpleasant smells such as rotting flesh, vomit, urine, feces, smoke, or others. Phantosmia often results from damage to the [[nervous tissue]] in the [[olfactory]] system. The damage can be caused by [[viral infection]], [[brain tumor]], [[Physical trauma|trauma]], [[surgery]], and possibly exposure to [[toxin]]s or [[drug]]s.<ref>[http://www.doctorhoffman.com/wwphant.htm Phantom smells<!-- Bot generated title -->]</ref> Phantosmia can also be induced by [[epilepsy]] affecting the [[olfactory cortex]] and is also thought to possibly have [[psychiatric]] origins.{{Citation needed|date=September 2007}} Phantosmia is different from [[parosmia]], in which a smell is actually present, but perceived differently from its actual smell.

−

===[[Tactile hallucinations]]===

+

Olfactory hallucinations can also appear in some cases of associative imagination, for example, while watching a romance movie, where the man gifts roses to the woman, the viewer senses the roses' odor (which in fact does not exist).

−

Tactile hallucinations create the sensation of tactile sensory input, simulating various types of pressure to the skin or other organs. A subtype of tactile hallucination that creates the sensation of insects crawling underneath the skin, called [[formication]], is often associated with prolonged [[cocaine]] or [[amphetamine]] use or with withdrawal from [[alcohol]] or [[Benzodiazepines]]. However, formication may also be the result of major hormonal changes (such as menopause), peripheral neuropathy, high fevers, Lyme disease, skin cancer, and more.

Tactile hallucinations are the illusion of tactile sensory input, simulating various types of pressure to the skin or other organs. One subtype of tactile hallucination, [[formication]], is the sensation of insects crawling underneath the skin and is frequently associated with prolonged [[cocaine]] or [[amphetamine]] use<ref name="Berrios G E 1982">{{cite journal | author = Berrios G E | year = 1982 | title = Tactile Hallucinations | url = | journal = Journal of Neurology, Neurosurgery and Psychiatry | volume = 45 | issue = 4| pages = 285–293 | doi = 10.1136/jnnp.45.4.285 }}</ref> or with withdrawal from [[alcohol]] or [[benzodiazepines]]. However, formication may also be the result of normal hormonal changes such as [[menopause]], or disorders such as [[peripheral neuropathy]], high fevers, [[Lyme disease]], [[skin cancer]], and more.<ref name="Berrios G E 1982"/>

+

===Gustatory===

+

This type of hallucination is the perception of taste without a stimulus. These hallucinations, which are typically strange or unpleasant, are relatively common among individuals who have certain types of [[epilepsy|focal epilepsy]], especially [[temporal lobe epilepsy]]. The regions of the brain responsible for gustatory hallucination in this case are the [[insula]] and the superior bank of the [[sylvian fissure]].<ref name=textbuk>Panayiotopoulos, Chrysostomos P. A clinical guide to epileptic syndromes and their treatment: based on the ILAE classification and practice parameter guidelines. 2. ed. London: Springer, 2007.</ref><ref>Barker, P. 1997. Assessment in Psychiatric and Mental Health Nursing In the Search of the Whole Person. UK: Nelson Thornes Ltd. p245.</ref>

−

==Scientificexplanations==

+

===Generalsomatic sensations===

+

General somatic sensations of a hallucinatory nature are experienced when an individual feels that his body is being mutilated i.e. twisted, torn, or disembowelled. Other reported cases are invasion by animals in the person's internal organs such as snakes in the stomach or frogs in the rectum. The general feeling that one's flesh is decomposing is also classified under this type of hallucination.<ref>Barker, P. 1997. Assessment in Psychiatric and Mental Health Nursing in Search of the Whole Person. UK: Nelson Thornes Ltd. P245.</ref>

−

Various theories have been put forward to explain the occurrence of hallucinations. When [[psychodynamic]] ([[Freud|Freudian]]) theories were popular in psychiatry, hallucinations were seen as a projection of unconscious wishes, thoughts and wants. As biological theories have become orthodox, hallucinations are more often thought of (by psychiatrists at least) as being caused by functional deficits in the [[brain]]. With reference to mental illness, the function (or dysfunction) of the [[neurotransmitter]] [[dopamine]] is thought to be particularly important<ref>[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12505794&dopt=Abstract Kapur S. (2003)] Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia. ''American Journal of Psychiatry'', 160(1), 13-23.<br></ref>.

+

==Cause==

+

{{See also|Psychosis#Causes|l1=Psychosis (causes)}}

+

Hallucinations can be caused by a number of factors.

−

[[Psychology|Psychological]]research has argued that hallucinations may result from biases in what are known as [[metacognition|metacognitive]] abilities<ref>[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2404293&dopt=Abstract Bentall RP. (1990)] The illusion of reality: a review and integration of psychological research on hallucinations. ''Psychological Bulletin'', 107(1), 82-95.<br></ref>. These are abilities that allow us to monitor or draw inferences from our own internal psychological states (such as [[intention]]s, [[memory|memories]], [[belief]]s and [[thought]]s). The ability to discriminate between self-generated and external sources of [[information]] is considered to be an important metacognitive skill and one which may break down to cause hallucinatory experiences. Projection of an internal state or a person's own reaction to another may arise in the form of hallucinations, especially auditory hallucinations. A few scientists have argued that such hallucinations may be the result of other conscious thoughts.

+

===Hypnagogichallucination===

+

{{main|Hypnagogia}}

+

These hallucinations occur just before falling asleep, and affect a surprisingly high proportion of the population (in one survey 37% of the respondents experienced them twice a week <ref name=Ohayon>{{cite journal|author=Maurice M. Ohayon, Robert G. Priest, Malija Caulet, and Christian Guilleminault |title=Hypnagogic and Hypnopompic Hallucinations: Pathological Phenomena?|journal=The British Journal of Psychiatry |volume=169 |issue=4 |pages=459–67|doi=10.1192/bjp.169.4.459|pmid=8894197|year=1996}}</ref>). The hallucinations can last from seconds to minutes, all the while the subject usually remains aware of the true nature of the images. These may be associated with [[narcolepsy]]. Hypnagogic hallucinations are sometimes associated with brainstem abnormalities, but this is rare.<ref name=manford>{{cite journal |author=Manford M, Andermann F |title=Complex visual hallucinations. Clinical and neurobiological insights |journal=Brain |volume=121 |issue=(Pt 10) |pages=1819–40 |year=1998 |month=Oct |pmid=9798740 |url=http://brain.oxfordjournals.org/cgi/content/abstract/121/10/1819 |doi=10.1093/brain/121.10.1819}}</ref>

−

==VisualHallucination Subtypes==

+

===Peduncularhallucinosis===

+

{{main|Peduncular hallucinosis}}

+

Peduncular means pertaining to the [[Cerebral peduncle|peduncle]], which is a neural tract running to and from the [[pons]] on the [[brain stem]]. These hallucinations usually occur in the evenings, but not during drowsiness, as in the case of hypnagogic hallucination. The subject is usually fully conscious and then can interact with the hallucinatory characters for extended periods of time. As in the case of [[hypnagogic hallucinations]], insight into the nature of the images remains intact. The false images can occur in any part of the visual field, and are rarely [[wikt:polymodal|polymodal]].<ref name=manford/>

+

===Delirium tremens===

+

{{main|Delirium tremens}}

+

One of the more enigmatic forms of visual hallucination is the highly variable, possibly polymodal [[delirium tremens]]. Individuals suffering from delirium tremens may be agitated and confused, especially in the later stages of this disease. Insight is gradually reduced with the progression of this disorder. Sleep is disturbed and occurs for a shorter period of time, with [[rapid eye movement sleep]].

−

===PeduncularHallucinosis===

+

===Parkinson'sdisease and Lewy body dementia===

−

Peduncularmeanspertainingtothe [[peduncle]],whichisanamegiventoaneuraltractrunningtoandfrom the [[pons]]. Thesehallucinationsoccurmostoftenintheevenings, butnotduringdrowsinessasinthecaseofhypnagogichallucinationasdescribedabove. The subject isusuallyfully conscious and caninteractwiththehallucinatorycharactersforextendedperiodsoftime. Asinthecaseof [[hypnagogichallucinations]],insightintothenatureoftheimagesremainsintact.Thefalseimages canoccur in anypart of the visualfield, and are rarely [[wikt:polymodal|polymodal]].<ref>[http://brain.oxfordjournals.org/cgi/content/abstract/121/10/1819Manford and Andermann(1998)] Complexvisualhallucinations.Clinical and Neurobiologicalinsights''Brain'',121(10),1819-1840.<br></ref>.

+

[[Parkinson'sdisease]]islinkedwith [[Dementia with Lewy bodies|Lewy body dementia]] fortheirsimilarhallucinatorysymptoms.Thesymptomsstrikeduringtheeveninginany part of the visual field, and are rarely [[wikt:polymodal|polymodal]]. Thesegueintohallucinationmaybeginwithillusions<ref>[http://www.nytimes.com/2006/02/14/health/14case.html?ex=1151121600&en=04560d31e7926bee&ei=5070 Mark Derr (2006)] Marilyn and Me, "TheNewYorkTimes"February14,2006<br></ref>wheresensoryperceptionisgreatlydistorted, but no novel sensory information is present. These typically last for several minutes, during which time the subject maybeeither conscious and normalordrowsy/inaccessible.Insightintothesehallucinationsisusuallypreservedand [[REM sleep]] is usually reduced. Parkinson'sdiseaseisusuallyassociated with a degraded [[substantianigra]] parscompacta,butrecentevidencesuggeststhatPDaffectsanumberofsites in thebrain. Some places of noted degradation include the median [[raphenuclei]], the [[noradrenergic]] parts of the [[locuscoeruleus]], and the[[cholinergic]] neuronsinthe[[parabrachial area]] and [[pedunculopontine]]nucleiofthe [[tegmentum]].<ref name=manford/>

−

===DeliriumTremens===

+

===Migrainecoma===

−

Oneofthe most enigmatic forms of visual hallucinations are the highly variable, possibly polymodal [[Delirium Tremens]], which is a form of [[withdrawal]] from alcohol in people with late-stage [[alcoholism]]. As the name suggests, the subject is usually agitated and confused, especially in the later stages of this disease. Insight is gradually reduced with the progression of this disorder. Sleep is disturbed and occurs for a shorter period of time, with [[Rapid eye movement|REM]] overflow. <ref>[http://brain.oxfordjournals.org/cgi/content/abstract/121/10/1819 Manford and Andermann (1998)] Complex visual hallucinations. Clinical and Neurobiological insights''Brain'', 121(10),1819-1840.<br></ref>.

+

{{seealso|Migraineaura|Scintillatingscotoma}}

+

This type of hallucination is usually experienced during the recovery from a comatose state. The migraine coma can last for up to two days, and a state of depression is sometimes [[Comorbidity|comorbid]]. The hallucinations occur during states of full consciousness, and insight into the hallucinatory nature of the images is preserved. It has been noted that ataxic lesions accompany the migraine coma.<ref name=manford/>

−

===Parkinson'sdiseaseand Lewy body Dementia===

+

===CharlesBonnetsyndrome===

−

[[Parkinson'sdisease]] is linkedwith[[DementiawithLewybodies|LewybodyDementia]]fortheir similar hallucinatory symptoms. The symptomsstrikeduringtheeveninginanypartof the visualfieldandarerarelypolymodal. The segue into hallucinations maystartwithillusions<ref>[http://www.nytimes.com/2006/02/14/health/14case.html?ex=1151121600&en=04560d31e7926bee&ei=5070MarkDerr (2006)] Marilyn and Me, "The New York Times" Feb. 14th, 2006 <br></ref> where sensory perception is greatly distorted, but nonovelsensoryinformationispresent.These typically last for several minutes, during which time the subject may be either conscious and normal or drowsy/inaccessible. Insightintothese hallucinations is usually preservedand[[REMsleep]]is usually reduced. Parkinson's disease is usually associated with a degraded [[substantia nigra]]parscompacta, butrecentevidencesuggests that PDaffects a numberof sites in the brain. Someplacesofnoteddegradationincludethemedianraphe nuclei, thenoradrenergicpartsofthelocuscoeruleusandthe[[cholinergic]]neuronsinthe[[parabrachial]]and[[pedunculopontine]]nucleiofthe [[tegmentum]]. <ref>[http://brain.oxfordjournals.org/cgi/content/abstract/121/10/1819Manford and Andermann (1998)] Complex visual hallucinations. Clinical and Neurobiological insights''Brain'', 121(10), 1819-1840.<br></ref>.

+

[[CharlesBonnet syndrome]] is thenamegiventovisualhallucinationsexperiencedbyblindpatients. The hallucinationscanusuallybedispersedbyopeningorclosing the eyelidsuntilthevisualimagesdisappear. The hallucinations usuallyoccurduringthemorningorevening, but arenotdependentonlowlightconditions. Theseprolonged hallucinations usually donotdisturbthepatientsverymuch, astheyareaware that theyarehallucinating.<refname=manford/>Adifferentialdiagnosisareopthalmopathichallucinations.<ref>{{citejournal|author=Engmann, Birk|title=Phosphenesandphotopsias-ischaemicoriginorsensorialdeprivation?-Casehistory|journal=ZNeuropsychol.|volume=19|issue=1|pages=7–13|year=2008|doi=10.1024/1016-264X.19.1.7|url=http://www.psycontent.com/content/m507n73711u73652/?p=400b10f998844a6abe524fcf44626323&pi=1|language=German}}</ref>

−

===MigraineComa===

+

===Focalepilepsy===

−

Thistypeofhallucinationisusuallyexperiencedduring the recoveryfromacomatosestate.Themigrainecomacanlastforuptotwodaysandastate of depressionissometimescomorbid.Thehallucinationsoccurduringstatesoffullconsciousness and insightintothehallucinatorynature of the imagesispreserved.Ithasbeennotedthatataxiclesionsaccompany the migrainecoma.<ref>[http://brain.oxfordjournals.org/cgi/content/abstract/121/10/1819ManfordandAndermann(1998)]Complex visual hallucinations.Clinical and Neurobiologicalinsights''Brain'',121(10),1819-1840.<br></ref>.

+

Visualhallucinationsdueto[[focalseizures]]differdepending on the regionofthebrainwheretheseizureoccurs.Forexample,visualhallucinationsduring[[occipitallobe]]seizuresaretypically visions of brightlycolored,geometricshapesthatmaymoveacrossthe[[visualfield]],multiply, or form concentric rings and generallypersistfrom a few seconds to a few minutes. They are usually unilateral and localized toonepart of the visualfieldonthecontralateralsideoftheseizure focus,typically the temporalfield. However,unilateralvisionsmovinghorizontallyacross the [[visual field]]begin on the contralateral side and movetowardsthe ipsilateralside.<ref name="textbuk"/><ref name="ncbi.nlm.nih.gov" />

−

===CharlesBonnetSyndrome===

+

[[Temporallobeepilepsy|Temporal lobe seizures]], on the other hand, can produce complex visual hallucinations of people, scenes, animals, and more as well as distortions of [[visual perception]]. Complex hallucinations may appear real or unreal, may or may not be distorted with respect to size, and may seem disturbing or affable, among other variables. One rare but notable type of hallucination is [[heautoscopy]], a hallucination of a mirror image of one's self. These "other selves" may be perfectly still or performing complex tasks, may be an image of a younger self or the present self, and tend to be only briefly present. Complex hallucinations are a relatively uncommon finding in temporal lobe epilepsy patients. Rarely, they may occur during occipital focal seizures or in [[parietal lobe]] seizures.<ref name="textbuk"/>

−

[[Charles Bonnet Syndrome]] is the name given to visual hallucinations experienced by blind patients. The hallucinations can usually be dispersed by opening or closing the eyelids until the visual images disappear. The hallucinations usually occur during the morning or evening, but are not dependent on low light conditions. These prolonged hallucinations usually do not disturb the patients very much as they are aware that they are hallucinating. <ref>[http://brain.oxfordjournals.org/cgi/content/abstract/121/10/1819 Manford and Andermann (1998)] Complex visual hallucinations. Clinical and Neurobiological insights''Brain'', 121(10), 1819-1840.<br></ref>.

Visual hallucinations due to focal [[seizures]] differ depending on the region of the brain where the seizure occurs. For example, visual hallucinations during [[occipital lobe]] seizures are typically visions of brightly colored, geometric shapes that may move across the visual field, multiply, or form concentric rings and generally persist from a few seconds to a few minutes. They are usually unilateral and localized to one part of the visual field on the ipsilateral side of the seizure focus, typically the temporal field. However, unilateral visions moving horizontally across the [[visual field]] begin on the contralateral side and move towards the ipsilateral side.<ref name=book>Panayiotopoulos, Chrysostomos P. A clinical guide to epileptic syndromes and their treatment: based on the ILAE classification and practice parameter guidelines. 2. ed. London: Springer, 2007.</ref>

+

+

===Drug-induced hallucination===

+

{{main|Hallucinogen}}

+

Drug-induced hallucinations are caused by the consumption of psychoactive substances such as [[deliriant]]s, [[psychedelics]], certain stimulants, and [[opiate]]s, which are known to cause visual and auditory hallucinations. Some psychedelics such as [[Lysergic acid diethylamide]], [[cannabis]], and [[psilocybin]] can cause hallucinations that range from a spectrum of mild to severe. Opiates are also a popular drug used to induce hallucinations, especially in larger doses. This as well as other drugs that induce hallucinations can cause severe mental and physical damage. Some of the most common opiates are [[opium]], [[heroin]] and [[morphine]]. Despite the addictive properties of some of these drugs (mainly opiates and mental dependencies in some cannabis users), others can be used in psychotherapy to treat mental disorders, addiction and even experiments.<ref name="Human Brain Mapping, DOI: 10.1002/hbm.21381">{{cite web |last=Frood |first=Arran |title=Drug Hallucinations Look Real in the Brain |url=http://www.newscientist.com/article/dn20978-drug-hallucinations-look-real-in-the-brain.html |publisher=newscientist.com |accessdate=October 25, 2011}}</ref>

+

+

===Sensory deprivation hallucination===

+

+

Hallucinations can be caused by [[sense deprivation]] when it occurs for prolonged periods of time, and almost always occur in the modality being deprived (visual for blindfolded/darkness, auditory for muffled conditions, etc.)

+

+

===Experimentally-induced hallucinations ===

+

+

''Main article'' : [[Hallucinations in the sane]]

+

+

==Pathophysiology==

+

{{Cleanup|reason= it has weird layout and structure|date=April 2013}}

+

+

===Visual===

+

+

Sometimes internal imagery can overwhelm the sensory input from external stimuli when sharing neural pathways, or if indistinct stimuli is perceived and manipulated to match one's expectations or beliefs, especially about the environment. This can result in a hallucination,<ref>{{cite book|last=Horowitz|first=M.|title=Hallucinations: An information-processing approach|year=1975|publisher=Wiley|location=New York|pages=163–194}}</ref> and this effect is sometimes exploited to form an [[optical illusion]].

+

+

There are 3 pathophysiologic mechanisms thought to account for complex visual hallucinations. These mechanisms consist of the following:

Another thing that may cause visual hallucinations is prolonged visual deprivation. In a study where 13 healthy people were blindfolded for 5 days, 10 out of the 13 subjects reported visual hallucinations. This finding lends strong support to the idea that the simple loss of normal visual input is sufficient to cause visual hallucinations.<ref name="ncbi.nlm.nih.gov"/>

+

+

===Psychodynamic view===

+

+

Various theories have been put forward to explain the occurrence of hallucinations. When [[psychodynamic]] ([[Freud]]ian) theories were popular in psychology, hallucinations were seen as a projection of unconscious wishes, thoughts and wants. As biological theories have become orthodox, hallucinations are more often thought of (by psychologists at least) as being caused by functional deficits in the [[Human brain|brain]]. With reference to mental illness, the function (or dysfunction) of the [[neurotransmitters]] [[glutamate]] and [[dopamine]] are thought to be particularly important.<ref>{{cite journal |author=Kapur S |title=Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia |journal=Am J Psychiatry |volume=160 |issue=1 |pages=13–23 |year=2003 |month=Jan |pmid=12505794 |url=http://ajp.psychiatryonline.org/cgi/pmidlookup?view=long&pmid=12505794 |doi=10.1176/appi.ajp.160.1.13}}<br></ref> The Freudian interpretation may have an aspect of truth, as the biological hypothesis explains the physical interactions in the brain, while the Freudian deals with the origin of the theme of the hallucination.

+

[[Psychology|Psychological]] research has argued that hallucinations may result from biases in what are known as [[metacognition|metacognitive]] abilities.<ref>{{cite journal |author=Bentall RP |title=The illusion of reality: a review and integration of psychological research on hallucinations |journal=Psychol Bull |volume=107 |issue=1 |pages=82–95 |year=1990 |month=Jan |pmid=2404293 |url=http://content.apa.org/journals/bul/107/1/82 |doi=10.1037/0033-2909.107.1.82}}</ref>

+

+

===Information processing perspective===

+

+

These are abilities that allow us to monitor or draw inferences from our own internal psychological states (such as [[intention]]s, [[memory|memories]], [[belief]]s and [[thought]]s). The ability to discriminate between internal (self-generated) and external (stimuli) sources of [[information]] is considered to be an important metacognitive skill, but one which may break down to cause hallucinatory experiences. Projection of an internal state (or a person's own reaction to another's) may arise in the form of hallucinations, especially auditory hallucinations. A recent hypothesis that is gaining acceptance concerns the role of overactive top-down processing, or strong perceptual expectations, that can generate spontaneous perceptual output (that is, hallucination).<ref>{{cite journal |author=Grossberg S |title=How hallucinations may arise from brain mechanisms of learning, attention, and volition |journal=J Int Neuropsychol Soc |volume=6 |issue=5 |pages=583–92 |year=2000 |month=Jul |pmid=10932478 |doi=10.1017/S135561770065508X }}</ref>

The most common modality referred to when people speak of hallucinations. These include the phenomena of seeing things which are not present or visual perception which does not reconcile with the physical, consensus reality. There are many different causes, which have been classed as psychophysiologic (a disturbance of brain structure), psychobiochemical (a disturbance of [[neurotransmitters]]), psychodynamic (an emergence of the unconscious into consciousness), and psychological (e.g. meaningful experiences consciousness), this is also the case in Alzheimer's disease. Numerous disorders can involve visual hallucinations, ranging from psychotic disorders to dementia to migraine, but experiencing visual hallucinations does not in itself mean there is necessarily a disorder. Visual hallucinations are associated with organic disorders of the brain and with drug- and alcohol-related illness,<ref>semple,David."oxford hand book of psychiatry" oxford press.2005.</ref> and not typically considered the result of a psychiatric disorder.<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660156/ Visual Hallucinations: Differential Diagnosis and Treatment (2009)]</ref>

+

+

====Schizophrenic hallucination====

+

Hallucinations may be caused by [[schizophrenia]]. Schizophrenia is a mental disorder in which there is an inability to tell the difference between real and unreal experiences, to think logically, have contextually appropriate emotions, and to function in social situations.<ref>Stannard, Lia. "Schizophrenia Types of Hallucinations." LiveStrong. Demand Media, Inc., 11 May 2011. Web. 14 Dec 2011.</ref>

+

+

During hallucination induced by schizophrenia there are many abnormalities in the brain, particularly in the region that processes voices and sounds (for those who experience auditory hallucinations) and visual processing (visual hallucinations). Researchers found that a possible cause for these hallucinations were abnormalities in gray matter and general functioning that combines interpreting sounds, voices and visuals, as well as regulating emotions.<ref>{{cite web|last=-Bonmatí,|title=Hallucinations In Schizophrenia Linked To Brain Area That Processes Voices|first=Luis Martí|url=http://www.sciencedaily.com/releases/2007/07/070731085526.htm|work=M.D., Ph.D.,|publisher=ScienceDaily|accessdate=oct, 30 2012}}</ref>

+

+

====Neuroanatomical correlates====

+

{{Main|Neuroscience of hallucinations}}

+

+

Normal everyday procedures like getting an MRI (Magnetic Resonance Imaging) have been used to find out more about auditory and verbal hallucinations. "Functional magnetic resonance imaging (fMRI) and repetitive transcranial magnetic stimulation (rTMS) were used to explore the pathophysiology of auditory/verbal hallucinations (AVHs)"<ref name="Probing the Pathophysiology of auditory/verbal Hallucinations">{{cite web|last=Hoffman|first=Ralph E.|url=http://ukpmc.ac.uk/articles/PMC2634833//reload=0;jsessionid=sqYunY2bgSDM4miop23B.4|title=Probing the pathophysiology of auditory/verbal hallucinations by combining functional magnetic resonance imaging and transcranial magnetic stimulation|publisher=from Cereb Cortex. 2007. November.17(11): 2733–2743.}}</ref> Throughout the exploring through MRI's of patients,there were "lower levels of hallucination-related activation in Broca’s area strongly predicted greater rate of response to left temporoparietal rTMS."<ref name="Probing the Pathophysiology of auditory/verbal Hallucinations">{{cite web|last=Hoffman|first=Ralph E.|url=http://ukpmc.ac.uk/articles/PMC2634833//reload=0;jsessionid=sqYunY2bgSDM4miop23B.4|publisher=from Cereb Cortex. 2007. November.17(11): 2733–2743.}}</ref>

Also through fMRI's, it is found that there can be better understandings on why hallucinations happen in the brain, by understanding emotion's and cognition and how it can prompt physical reactions that can help result in a hallucination. It suggests the theory that "motivations in the body and mind can drive us to certain behaviors that we act in, such as survival instinct and intuition" and that they can work in a hand in hand like fashion. It can also be viewed as a symbolic "homeostasis" that can have adverse effects by having these hallucinations and / or mental illnesses. The amygdala has also been seen to relate to this finding by contributing a "declarative judgement of emotional salience" as well as affecting both "efferent and afferent representational levels of affective autonomic responses in the brain".<ref name="Hugo D. Critchely">{{cite journal|last=Critchley|first=Hugo D.|title=Psychophysiology of neural, cognitive and affective integration: fMRI and autonomic indicants|publisher=U.S. National Library of Medicine|pmc=2722714|year=2009|volume=73|issue=2|pages=88–94|doi=10.1016/j.ijpsycho.2009.01.012|journal=International Journal of Psychophysiology|pmid=19414044}}</ref>

+

+

====Pathophysiological mechanisms====

+

"The left superior temporal cortex, which supports linguistic functions, has consistently been reported to activate during

+

auditory–verbal hallucinations in schizophrenia patients"<ref>{{cite journal|last=Plaze et al.|coauthors=Bartes-Faz, Martinot, Januel, Belliever, De Beaurepraire, Chanraud, Andoh, Lefaucher,Artiges, Pallier, Martinot|title=Schizophrenia Research|journal=Science Direct|year=2006|pages=109–115|url=http://www.sciencedirect.com|accessdate=13 November 2012}}</ref> The Charles Bonnet Syndrome supports the visual cortex deafferentiation proposal. There is irritation in the visual cortex when hallucination occur, which could suggest why it is reported that images that are not real are seen. Although many sufferers of the [[Charles Bonnet Syndrome]] are elderly, it can occur in anyone.<ref>{{cite web|title=Charles Bonnet Syndrome|url=http://www.circee.org/syndrome-de-charles-bonnet.html|accessdate=13 November 2012}}</ref> The reticular activation system can be used to support the neurotransmitters ([[dopamine]] and [[norepinephrine]]) effect on hallucinations.

+

+

==Treatments==

+

There are few treatments for many types of hallucinations. However, for those hallucinations caused by mental disease, a psychologist or psychiatrist should be alerted, and treatment will be based on the observations of those doctors. [[Antipsychotic]] and [[atypical antipsychotic]] medication may also be utilized to treat the illness if the symptoms are severe and cause significant distress.{{Citation needed|date=August 2011}} For other causes of hallucinations there is no factual evidence to support any one treatment is scientifically tested and proven. However, abstaining from [[hallucinogen]]ic drugs, managing stress levels, living healthily, and getting plenty of sleep can help reduce the prevalence of hallucinations. In all cases of hallucinations, medical attention should be sought out and informed of one's specific symptoms.

−

[[Temporal lobe epilepsy|Temporal lobe seizures]], on the other hand, can produce complex visual hallucinations of people, scenes, animals, and more as well as distortions of [[visual perception]]. Complex hallucinations may appear real or unreal, may or may not be distorted with respect to size, and may seem disturbing or affable, among other variables. One rare but notable type of hallucination is [[heautoscopy]], a hallucination of a mirror image of one's self. These "other selves" may be perfectly still or performing complex tasks, may be an image of a younger self or the present self, and tend to be only briefly present. Complex hallucinations are a relatively uncommon finding in temporal lobe epilepsy patients. Rarely, they may occur during occipital focal seizures or in [[parietal lobe]] seizures.<ref name=book/>

−

[[Video:Dolly Zoom Examples|thumb|400px|right|Some examples of the dolly zoom effect simulating a type of visual illusion that a focal seizure may produce.]] Distortions in visual perception during a temporal lobe seizure may include size distortion (micropsia or macropsia), distorted perception of movement (where moving objects may appear to be moving very slowly or to be perfectly still), a sense that surfaces such as ceilings and even entire horizons are moving farther away in a fashion similar to the dolly zoom effect, and other illusions.<ref>Bien CG, Benninger FO, Urbach H, Schramm J, Kurthen M, Elger CE (2000) Localizing value of epileptic visual auras. Brain 123:244–253 [http://www.ncbi.nlm.nih.gov/pubmed/10648433?dopt=Abstract/ PubMed]</ref> Even when consciousness is impaired, insight into the hallucination or illusion is typically preserved.

This article is in need of attention from a psychologist/academic expert on the subject.Please help recruit one, or improve this page yourself if you are qualified.This banner appears on articles that are weak and whose contents should be approached with academic caution

.

Hallucination

Classification and external resources

Template:PxMy eyes at the moment of the apparitions by August Natterer, a German artist who created many drawings of his hallucinations.

A hallucination is a perception in the absence of apparent stimulus which has qualities of real perception. Hallucinations are vivid, substantial, and located in external objective space. They are distinguished from the related phenomena of dreaming, which does not involve wakefulness; illusion, which involves distorted or misinterpreted real perception; imagery, which does not mimic real perception and is under voluntary control; and pseudohallucination, which does not mimic real perception, but is not under voluntary control.[1]
Hallucinations also differ from "delusional perceptions", in which a correctly sensed and interpreted stimulus (i.e. a real perception) is given some additional (and typically bizarre) significance.

A mild form of hallucination is known as a disturbance, and can occur in any of the senses above. These may be things like seeing movement in peripheral vision, or hearing faint noises and/or voices.
Auditory hallucinations are very common in paranoid schizophrenia. They may be benevolent (telling the patient good things about themselves) or malicious, cursing the patient etc. Auditory hallucinations of the malicious type are frequently heard like people talking about the patient behind their back. Like auditory hallucinations, the source of their visual counterpart can also be behind the patient's back. Their visual counterpart is the feeling of being looked-stared at, usually with malicious intent. Frequently, auditory hallucinations and their visual counterpart are experienced by the patient together.

Contents

One study from as early as 1895[2] reported that approximately 10% of the population experienced hallucinations. A 1996-1999 survey of over 13,000 people[3] reported a much higher figure, with almost 39% of people reporting hallucinatory experiences, 27% of which were daytime hallucinations, mostly outside the context of illness or drug use. From this survey, olfactory (smell) and gustatory (taste) hallucinations seem the most common in the general population.

Hallucinations may be manifested in a variety of forms.[4] Various forms of hallucinations affect different senses, sometimes occurring simultaneously, creating multiple sensory hallucinations for those experiencing them.

Auditory hallucinations (also known as paracusia)[6] are the perception of sound without outside stimulus. Auditory hallucinations can be divided into two categories: elementary and complex. Elementary hallucinations are the perception of sounds such as hissing, whistling, an extended tone, and more. In many cases, tinnitus is an elementary auditory hallucination. However, some people who experience certain types of tinnitus, especially pulsatile tinnitus, are actually hearing the blood rushing through vessels near the ear. Because the auditory stimulus is present in this situation, it does not qualify as a hallucination.

Complex hallucinations are those of voices, music, or other sounds which may or may not be clear, may be familiar or completely unfamiliar, and friendly or aggressive, among other possibilities. Hallucinations of one or more talking voices are particularly associated with psychotic disorders such as schizophrenia, and hold special significance in diagnosing these conditions. However, many people not suffering from diagnosable mental illness may sometimes hear voices as well.[7] One important example to consider when forming a differential diagnosis for a patient with paracusia is lateral temporal lobe epilepsy. Despite the tendency to associate hearing voices, or otherwise hallucinating, and psychosis with schizophrenia or other psychiatric illnesses, it is crucial to take into consideration that even if a person does exhibit psychotic features, they do not necessarily suffer from a psychiatric disorder on its own. Disorders such as Wilson's disease, various endocrine diseases, numerous metabolic disturbances, multiple sclerosis, systemic lupus erythematosis, porphyria, sarcoidosis, and many others can present with psychosis.

Musical hallucinations are also relatively common in terms of complex auditory hallucinations and may be the result of a wide range of causes ranging from hearing-loss (such as in musical ear syndrome, the auditory version of Charles Bonnet syndrome), lateral temporal lobe epilepsy,[8] arteriovenous malformation,[9] stroke, lesion, abscess, or tumor.[10]

The Hearing Voices Movement is a support and advocacy group for people who hallucinate voices, but do not otherwise show signs of mental illness or impairment.

High caffeine consumption has been linked to an increase in the likelihood of experiencing auditory hallucinations. A study conducted by the La Trobe University School of Psychological Sciences revealed that as few as five cups of coffee a day could trigger the phenomenon.[11]

Command hallucinations are hallucinations in the form of commands; they can be auditory or inside of the persons mind and / or consciousness.[12] The contents of the hallucinations can range from the innocuous to commands to cause harm to the self or others.[12] Command hallucinations are often associated with schizophrenia. People experiencing command hallucinations may or may not comply with the hallucinated commands, depending on circumstances. Compliance is more common for non-violent commands.[13]
Command hallucinations are sometimes used in defense of a crime, often homicides. It is essentially a voice one hears and it tells them what to do. Sometimes they are quite benign directives such as "Stand up." or "Shut the door."[14] Whether it is a command for something simple or something that is a threat, it is still considered a "command hallucination." Some helpful questions that can assist one in figuring out if they may be suffering from this includes: "What are the voices telling you to do?","When did your voices first start telling you to do things?, "Do you recognize the person who is telling you to harm yourself (others)?", "Do you think you can resist doing what the voices are telling you to do?".[14]

Olfactory hallucinations can also appear in some cases of associative imagination, for example, while watching a romance movie, where the man gifts roses to the woman, the viewer senses the roses' odor (which in fact does not exist).

Olfactory hallucinations have also been reported in migraine, although the frequency of such hallucinations is unclear.[16][17]

This type of hallucination is the perception of taste without a stimulus. These hallucinations, which are typically strange or unpleasant, are relatively common among individuals who have certain types of focal epilepsy, especially temporal lobe epilepsy. The regions of the brain responsible for gustatory hallucination in this case are the insula and the superior bank of the sylvian fissure.[19][20]

General somatic sensations of a hallucinatory nature are experienced when an individual feels that his body is being mutilated i.e. twisted, torn, or disembowelled. Other reported cases are invasion by animals in the person's internal organs such as snakes in the stomach or frogs in the rectum. The general feeling that one's flesh is decomposing is also classified under this type of hallucination.[21]

These hallucinations occur just before falling asleep, and affect a surprisingly high proportion of the population (in one survey 37% of the respondents experienced them twice a week [22]). The hallucinations can last from seconds to minutes, all the while the subject usually remains aware of the true nature of the images. These may be associated with narcolepsy. Hypnagogic hallucinations are sometimes associated with brainstem abnormalities, but this is rare.[23]

Peduncular means pertaining to the peduncle, which is a neural tract running to and from the pons on the brain stem. These hallucinations usually occur in the evenings, but not during drowsiness, as in the case of hypnagogic hallucination. The subject is usually fully conscious and then can interact with the hallucinatory characters for extended periods of time. As in the case of hypnagogic hallucinations, insight into the nature of the images remains intact. The false images can occur in any part of the visual field, and are rarely polymodal.[23]

One of the more enigmatic forms of visual hallucination is the highly variable, possibly polymodal delirium tremens. Individuals suffering from delirium tremens may be agitated and confused, especially in the later stages of this disease. Insight is gradually reduced with the progression of this disorder. Sleep is disturbed and occurs for a shorter period of time, with rapid eye movement sleep.

Parkinson's disease is linked with Lewy body dementia for their similar hallucinatory symptoms. The symptoms strike during the evening in any part of the visual field, and are rarely polymodal. The segue into hallucination may begin with illusions[24] where sensory perception is greatly distorted, but no novel sensory information is present. These typically last for several minutes, during which time the subject may be either conscious and normal or drowsy/inaccessible. Insight into these hallucinations is usually preserved and REM sleep is usually reduced. Parkinson's disease is usually associated with a degraded substantia nigra pars compacta, but recent evidence suggests that PD affects a number of sites in the brain. Some places of noted degradation include the median raphe nuclei, the noradrenergic parts of the locus coeruleus, and the cholinergic neurons in the parabrachial area and pedunculopontine nuclei of the tegmentum.[23]

This type of hallucination is usually experienced during the recovery from a comatose state. The migraine coma can last for up to two days, and a state of depression is sometimes comorbid. The hallucinations occur during states of full consciousness, and insight into the hallucinatory nature of the images is preserved. It has been noted that ataxic lesions accompany the migraine coma.[23]

Charles Bonnet syndrome is the name given to visual hallucinations experienced by blind patients. The hallucinations can usually be dispersed by opening or closing the eyelids until the visual images disappear. The hallucinations usually occur during the morning or evening, but are not dependent on low light conditions. These prolonged hallucinations usually do not disturb the patients very much, as they are aware that they are hallucinating.[23] A differential diagnosis are opthalmopathic hallucinations.[25]

Visual hallucinations due to focal seizures differ depending on the region of the brain where the seizure occurs. For example, visual hallucinations during occipital lobe seizures are typically visions of brightly colored, geometric shapes that may move across the visual field, multiply, or form concentric rings and generally persist from a few seconds to a few minutes. They are usually unilateral and localized to one part of the visual field on the contralateral side of the seizure focus, typically the temporal field. However, unilateral visions moving horizontally across the visual field begin on the contralateral side and move towards the ipsilateral side.[19][26]

Temporal lobe seizures, on the other hand, can produce complex visual hallucinations of people, scenes, animals, and more as well as distortions of visual perception. Complex hallucinations may appear real or unreal, may or may not be distorted with respect to size, and may seem disturbing or affable, among other variables. One rare but notable type of hallucination is heautoscopy, a hallucination of a mirror image of one's self. These "other selves" may be perfectly still or performing complex tasks, may be an image of a younger self or the present self, and tend to be only briefly present. Complex hallucinations are a relatively uncommon finding in temporal lobe epilepsy patients. Rarely, they may occur during occipital focal seizures or in parietal lobe seizures.[19]

Distortions in visual perception during a temporal lobe seizure may include size distortion (micropsia or macropsia), distorted perception of movement (where moving objects may appear to be moving very slowly or to be perfectly still), a sense that surfaces such as ceilings and even entire horizons are moving farther away in a fashion similar to the dolly zoom effect, and other illusions.[27] Even when consciousness is impaired, insight into the hallucination or illusion is typically preserved.

Drug-induced hallucinations are caused by the consumption of psychoactive substances such as deliriants, psychedelics, certain stimulants, and opiates, which are known to cause visual and auditory hallucinations. Some psychedelics such as Lysergic acid diethylamide, cannabis, and psilocybin can cause hallucinations that range from a spectrum of mild to severe. Opiates are also a popular drug used to induce hallucinations, especially in larger doses. This as well as other drugs that induce hallucinations can cause severe mental and physical damage. Some of the most common opiates are opium, heroin and morphine. Despite the addictive properties of some of these drugs (mainly opiates and mental dependencies in some cannabis users), others can be used in psychotherapy to treat mental disorders, addiction and even experiments.[28]

Hallucinations can be caused by sense deprivation when it occurs for prolonged periods of time, and almost always occur in the modality being deprived (visual for blindfolded/darkness, auditory for muffled conditions, etc.)

Sometimes internal imagery can overwhelm the sensory input from external stimuli when sharing neural pathways, or if indistinct stimuli is perceived and manipulated to match one's expectations or beliefs, especially about the environment. This can result in a hallucination,[29] and this effect is sometimes exploited to form an optical illusion.

There are 3 pathophysiologic mechanisms thought to account for complex visual hallucinations. These mechanisms consist of the following:

The second mechanism involves lesions that cause deafferentation of the visual system may lead to cortical release phenomenon, which includes visual hallucination.

The third mechanism is the reticular activating system, which has been linked to the genesis of visual hallucinations.[26]

Some specific classifications include: elementary hallucinations, which may entail flicks, specks, and bars of light (called phosphenes). Closed eye hallucinations in darkness, which are common to psychedelic drugs (i.e., LSD, mescaline). Scenic or "panoramic" hallucinations, which are not superimposed but vividly replace the entire visual field with hallucinatory content similarly to dreams;[30] such scenic hallucinations may occur in epilepsy[31] (in which they are usually stereotyped and experimental[32] in character), hallucinogen use,[30] and more rarely in catatonic schizophrenia[33][34] (cf. oneirophrenia), mania,[35] and brainstem lesions,[36] amongst others.

Another thing that may cause visual hallucinations is prolonged visual deprivation. In a study where 13 healthy people were blindfolded for 5 days, 10 out of the 13 subjects reported visual hallucinations. This finding lends strong support to the idea that the simple loss of normal visual input is sufficient to cause visual hallucinations.[26]

Various theories have been put forward to explain the occurrence of hallucinations. When psychodynamic (Freudian) theories were popular in psychology, hallucinations were seen as a projection of unconscious wishes, thoughts and wants. As biological theories have become orthodox, hallucinations are more often thought of (by psychologists at least) as being caused by functional deficits in the brain. With reference to mental illness, the function (or dysfunction) of the neurotransmittersglutamate and dopamine are thought to be particularly important.[37] The Freudian interpretation may have an aspect of truth, as the biological hypothesis explains the physical interactions in the brain, while the Freudian deals with the origin of the theme of the hallucination.
Psychological research has argued that hallucinations may result from biases in what are known as metacognitive abilities.[38]

These are abilities that allow us to monitor or draw inferences from our own internal psychological states (such as intentions, memories, beliefs and thoughts). The ability to discriminate between internal (self-generated) and external (stimuli) sources of information is considered to be an important metacognitive skill, but one which may break down to cause hallucinatory experiences. Projection of an internal state (or a person's own reaction to another's) may arise in the form of hallucinations, especially auditory hallucinations. A recent hypothesis that is gaining acceptance concerns the role of overactive top-down processing, or strong perceptual expectations, that can generate spontaneous perceptual output (that is, hallucination).[39]

The most common modality referred to when people speak of hallucinations. These include the phenomena of seeing things which are not present or visual perception which does not reconcile with the physical, consensus reality. There are many different causes, which have been classed as psychophysiologic (a disturbance of brain structure), psychobiochemical (a disturbance of neurotransmitters), psychodynamic (an emergence of the unconscious into consciousness), and psychological (e.g. meaningful experiences consciousness), this is also the case in Alzheimer's disease. Numerous disorders can involve visual hallucinations, ranging from psychotic disorders to dementia to migraine, but experiencing visual hallucinations does not in itself mean there is necessarily a disorder. Visual hallucinations are associated with organic disorders of the brain and with drug- and alcohol-related illness,[41] and not typically considered the result of a psychiatric disorder.[42]

Hallucinations may be caused by schizophrenia. Schizophrenia is a mental disorder in which there is an inability to tell the difference between real and unreal experiences, to think logically, have contextually appropriate emotions, and to function in social situations.[43]

During hallucination induced by schizophrenia there are many abnormalities in the brain, particularly in the region that processes voices and sounds (for those who experience auditory hallucinations) and visual processing (visual hallucinations). Researchers found that a possible cause for these hallucinations were abnormalities in gray matter and general functioning that combines interpreting sounds, voices and visuals, as well as regulating emotions.[44]

Normal everyday procedures like getting an MRI (Magnetic Resonance Imaging) have been used to find out more about auditory and verbal hallucinations. "Functional magnetic resonance imaging (fMRI) and repetitive transcranial magnetic stimulation (rTMS) were used to explore the pathophysiology of auditory/verbal hallucinations (AVHs)"[45] Throughout the exploring through MRI's of patients,there were "lower levels of hallucination-related activation in Broca’s area strongly predicted greater rate of response to left temporoparietal rTMS."[45]
What these findings could suggest is that "dominant hemisphere temporoparietal areas are involved in expressing AVHs, with higher levels of coactivation and/or coupling involving inferior frontal regions reinforcing underlying pathophysiology."[45]

Also through fMRI's, it is found that there can be better understandings on why hallucinations happen in the brain, by understanding emotion's and cognition and how it can prompt physical reactions that can help result in a hallucination. It suggests the theory that "motivations in the body and mind can drive us to certain behaviors that we act in, such as survival instinct and intuition" and that they can work in a hand in hand like fashion. It can also be viewed as a symbolic "homeostasis" that can have adverse effects by having these hallucinations and / or mental illnesses. The amygdala has also been seen to relate to this finding by contributing a "declarative judgement of emotional salience" as well as affecting both "efferent and afferent representational levels of affective autonomic responses in the brain".[46]

"The left superior temporal cortex, which supports linguistic functions, has consistently been reported to activate during
auditory–verbal hallucinations in schizophrenia patients"[47] The Charles Bonnet Syndrome supports the visual cortex deafferentiation proposal. There is irritation in the visual cortex when hallucination occur, which could suggest why it is reported that images that are not real are seen. Although many sufferers of the Charles Bonnet Syndrome are elderly, it can occur in anyone.[48] The reticular activation system can be used to support the neurotransmitters (dopamine and norepinephrine) effect on hallucinations.

There are few treatments for many types of hallucinations. However, for those hallucinations caused by mental disease, a psychologist or psychiatrist should be alerted, and treatment will be based on the observations of those doctors. Antipsychotic and atypical antipsychotic medication may also be utilized to treat the illness if the symptoms are severe and cause significant distress.[citation needed] For other causes of hallucinations there is no factual evidence to support any one treatment is scientifically tested and proven. However, abstaining from hallucinogenic drugs, managing stress levels, living healthily, and getting plenty of sleep can help reduce the prevalence of hallucinations. In all cases of hallucinations, medical attention should be sought out and informed of one's specific symptoms.