STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

XP_446892.1

Hypothetical protein (298 aa)

Predicted Functional Partners:

VMA1

Hypothetical protein (1033 aa)

0.940

ATP1

Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane (543 aa)

0.938

XP_447739.1

Hypothetical protein (211 aa)

0.937

XP_447453.1

Hypothetical protein (296 aa)

0.923

ATP2

Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane (507 aa)

0.923

ATP5

Hypothetical protein; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits [...] (207 aa)

ATP synthase protein 9; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (76 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

ATP1

ATP16

XP_449761.1

XP_445369.1

Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane

Hypothetical protein

0.997

ATP1

ATP2

XP_449761.1

XP_446820.1

Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane

Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane

0.999

ATP1

ATP5

XP_449761.1

XP_446859.1

Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane

Hypothetical protein; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits [...]

0.999

ATP1

ATP9

XP_449761.1

NP_818784.1

Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane

ATP synthase protein 9; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...]

0.995

ATP1

VMA1

XP_449761.1

XP_447421.1

Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane

Hypothetical protein

0.507

ATP1

VMA11

XP_449761.1

XP_445959.1

Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane

Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane

Hypothetical protein

0.999

ATP1

XP_447739.1

XP_449761.1

XP_447739.1

Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane

Hypothetical protein

0.987

ATP16

ATP1

XP_445369.1

XP_449761.1

Hypothetical protein

Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane

0.997

ATP16

ATP2

XP_445369.1

XP_446820.1

Hypothetical protein

Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane

0.999

ATP16

ATP5

XP_445369.1

XP_446859.1

Hypothetical protein

Hypothetical protein; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits [...]

0.999

ATP16

ATP9

XP_445369.1

NP_818784.1

Hypothetical protein

ATP synthase protein 9; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...]