Abstract

Therapeutic strategies in MS are generally based on treatment with anti-inflammatory, immunosuppressive or immunomodulatory agents. Most applied therapeutic agents in MS are: corticosteroids, cyclophosphamide, azathioprine, cyclosporine, interferon, total lymphoid irradiation, plasma exchange, monoclonal antibodies, copolymer-I and immunoglobulins. Modes of administration are: oral, intramuscular, intravenous or intrathecal; administration of drugs can be carried out by both a short course of high dose or a chronic low dose during an extended period.