The game is set in an alternate-universe version of Manhattan in 1907 which has been deserted and quarantined after an unexplained disaster called the “great disappearance” 5 years prior to the game's events.[citation needed]

Noteworthy for featuring a street-accurate recreation of Manhattan with many landmarks as well as the ability to use the New York City Subway and taxis to get around the island. Bridges such as the Brooklyn Bridge are present but are blocked off.