Machado-Joseph disease (MJD)—also called spinocerebellar ataxia Type 3 (SCA3)—is one of approximately 30 recognized, dominantly inherited forms of ataxia. Ataxia is a general term meaning lack of muscle control or coordination. MJD is characterized by slowly progressive clumsiness in the arms and legs, a staggering lurching gait that can be mistaken for drunkenness, difficulty with speech and swallowing, impaired eye movements sometimes accompanied by double vision or bulging eyes, and lower limb spasticity.

CureSCA, Cure Spino-Cerebellar Ataxia, is a charity dedicated to help patients and families affected by SpinoCerebellar Ataxia 3.

What we do

Our aim is to work collaboratively with leading Ataxia charities, reasearchers and health professionals to fund research studies that specifically focuses on slowing down the disease progression and improve the quality of life for patients with SCA3.