Professor Nicola Gray

ProfessorNicolaGray

Principal investigator

Contact details

Address

Street

The Queen’s Medical Research Institute
47 Little France Crescent

City

Edinburgh

Post Code

EH16 4TJ

Research Interests

Genes must be regulated to ensure that they are expressed at the right time and place and in the correct amounts. Failure in this process can lead to disease. Genes can be regulated at multiple steps including at the level of mRNA translation, the final step in producing proteins. Work in recent years has revealed that the mis-regulation of mRNA translation is important in the aetiology of a wide range of human diseases including reproductive, neurological and metabolic disorders. Our work examines how mRNAs are regulated at the level of translation and the consequences of their mis-regulation. Current projects in the laboratory investigate translational control events that contribute to reproductive health with a focus towards understanding normal and dysfunctional gametogenesis and early development. This is complemented by our work on host-viral interactions, since studying the mechanisms employed by viruses to subvert the host cell machinery has revealed many of the ways in which cells normally regulate protein production.

The University of Edinburgh

The University of Edinburgh is a charitable body, registered in Scotland, with registration number
SC005336, VAT Registration Number GB 592 9507 00, and is acknowledged by the UK authorities as a
“Recognised body” which has been
granted degree awarding powers.