Product Description

Rab7 belongs to the Rab family of small GTPases. Rab7 is located in the late endosome, lysosome, cytoplasmic vesicle, phagosome and melanosome. It is involved in the late endocytic transport and contributes to the maturation of phagosomes.

Currently there is no direct assay to measure the activation of Rab7 GTPases.

NewEast Biosciences Rab7 Activation Assay Kit is based on the configuration-specific monoclonal antibody that specifically recognizes Rab7-GTP, but not Rab7-GDP. Given the high affinity of monoclonal antibodies to their antigens, the activation assay could be performed in a short time. This assay provides the reliable results with consistent reproducibility.

These anti- Rab7-GTP monoclonal antibodies can also be used to monitor the activation of Rab7 in cells and in tissues by immunohistochemistry.