Word to the wise: When Lena Dunham appears on your talk show, no man is safe.

The Girls creator, who's never withheld her opinion publicly, played "Plead the Fifth" on Wednesday night's (October 10) episode of Watch What Happens Live, and answered everything from who she thinks is Taylor Swift's very worst ex-boyfriend to which man is the biggest misogynist in Hollywood.

"She felt it was time for her to talk about politics, and I never judged her for considering that a private domain, but I think she chose a really, really powerful time to speak out and I’m so moved and honored to be her friend," Dunham said.

Check out the clip above for more, including a tale of some serious drama on the Girls set.