Write-up:This case was reported by a physician in the frame of a study and described the occurrence of intussusception in a 3-month-old female subject who was vaccinated with ROTARIX (GlaxoSmithKline). On 2 October 2008, 3 days after vaccination with ROTARIX, the subject presented vomiting, irritability, abdominal distension and fever. The subject received ambulatory treatment with co-trimoxazole , acetaminophen and metaclopramide without improvement. On 06 October 2008 the subject was hospitalized. Subject''s physical examination showed abdominal distension, absence of bowel sounds and tympanites. The x-ray showed dilated loops, edema between loop and loop and bounden loop. The diagnosis made by clinical feature and abdominal x-ray was intestinal obstruction and intussusception. On 08 October 2008 the subject underwent a surgery in which ileocecocolic intussusception with 5cm length perforation in ileum and mesenteric adenitis was found. Reduction by taxis and intestinal resection of 8 cm length in terminal ileum with anastomosis was performed. The subject''s evolution was bad. Therefore on 15 October 2008 the subject underwent a 2nd surgery in which 50% anastomosis dehiscence and 8mm of new intestinal perforation was found. A new resection of 5 cm in ileum and new anastomosis was performed. The subject showed good evolution. On 27 October 2008 the subject was discharged in good conditions. The subject was treated with (Acetaminophen), Ranitidine, amikacin, metronidazole, midazolam, sodium bicarbonate and cefotaxime. The physician considered the events were possibly related to vaccination with ROTARIX.

Write-up:This case was reported by a physician in the frame of a study and described the occurrence of intussusception in a 3-month-old female subject who was vaccinated with ROTARIX (GlaxoSmithKline). On 2 October 2008, 3 days after vaccination with ROTARIX, the subject presented vomiting, irritability, abdominal distension and fever. The subject received ambulatory treatment with co-trimoxazole , acetaminophen and metaclopramide without improvement. On 06 October 2008 the subject was hospitalized. Subject''s physical examination showed abdominal distension, absence of bowel sounds and tympanites. The x-ray showed dilated loops, edema between loop and loop and bounden loop. The diagnosis made by clinical feature and abdominal x-ray was intestinal obstruction and intussusception. On 08 October 2008 the subject underwent a surgery in which ileocecocolic intussusception with 5cm length perforation in ileum and mesenteric adenitis was found. Reduction by taxis and intestinal resection of 8 cm length in terminal ileum with anastomosis was performed. The subject''s evolution was bad. Therefore on 15 October 2008 the subject underwent a 2nd surgery in which 50% anastomosis dehiscence and 8mm of new intestinal perforation was found. A new resection of 5 cm in ileum and new anastomosis was performed. The subject showed good evolution. On 27 October 2008 the subject was discharged in good conditions. The subject was treated with (Acetaminophen), Ranitidine, amikacin, metronidazole, midazolam, sodium bicarbonate and cefotaxime. The physician considered the events were possibly related to vaccination with ROTARIX.

Write-up:This case was reported by a physician in the frame of a study and described the occurrence of intussusception in a 3-month-old female subject who was vaccinated with ROTARIX (GlaxoSmithKline). On 2 October 2008, 3 days after vaccination with ROTARIX, the subject presented vomiting, irritability, abdominal distension and fever. The subject received ambulatory treatment with co-trimoxazole , acetaminophen and metaclopramide without improvement. On 06 October 2008 the subject was hospitalized. Subject''s physical examination showed abdominal distension, absence of bowel sounds and tympanites. The x-ray showed dilated loops, edema between loop and loop and bounden loop. The diagnosis made by clinical feature and abdominal x-ray was intestinal obstruction and intussusception. On 08 October 2008 the subject underwent a surgery in which ileocecocolic intussusception with 5cm length perforation in ileum and mesenteric adenitis was found. Reduction by taxis and intestinal resection of 8 cm length in terminal ileum with anastomosis was performed. The subject''s evolution was bad. Therefore on 15 October 2008 the subject underwent a 2nd surgery in which 50% anastomosis dehiscence and 8mm of new intestinal perforation was found. A new resection of 5 cm in ileum and new anastomosis was performed. The subject showed good evolution. On 27 October 2008 the subject was discharged in good conditions. The subject was treated with (Acetaminophen), Ranitidine, amikacin, metronidazole, midazolam, sodium bicarbonate and cefotaxime. The physician considered the events were possibly related to vaccination with ROTARIX.

Write-up:This case was reported by a physician in the frame of a study and described the occurrence of intussusception in a 3-month-old female subject who was vaccinated with ROTARIX (GlaxoSmithKline). On 2 October 2008, 3 days after vaccination with ROTARIX, the subject presented vomiting, irritability, abdominal distension and fever. The subject received ambulatory treatment with co-trimoxazole , acetaminophen and metaclopramide without improvement. On 06 October 2008 the subject was hospitalized. Subject''s physical examination showed abdominal distension, absence of bowel sounds and tympanites. The x-ray showed dilated loops, edema between loop and loop and bounden loop. The diagnosis made by clinical feature and abdominal x-ray was intestinal obstruction and intussusception. On 08 October 2008 the subject underwent a surgery in which ileocecocolic intussusception with 5cm length perforation in ileum and mesenteric adenitis was found. Reduction by taxis and intestinal resection of 8 cm length in terminal ileum with anastomosis was performed. The subject''s evolution was bad. Therefore on 15 October 2008 the subject underwent a 2nd surgery in which 50% anastomosis dehiscence and 8mm of new intestinal perforation was found. A new resection of 5 cm in ileum and new anastomosis was performed. The subject showed good evolution. On 27 October 2008 the subject was discharged in good conditions. The subject was treated with (Acetaminophen), Ranitidine, amikacin, metronidazole, midazolam, sodium bicarbonate and cefotaxime. The physician considered the events were possibly related to vaccination with ROTARIX.

Write-up:This case was reported by a physician in the frame of a study and described the occurrence of intussusception in a 3-month-old female subject who was vaccinated with ROTARIX (GlaxoSmithKline). On 2 October 2008, 3 days after vaccination with ROTARIX, the subject presented vomiting, irritability, abdominal distension and fever. The subject received ambulatory treatment with co-trimoxazole , acetaminophen and metaclopramide without improvement. On 06 October 2008 the subject was hospitalized. Subject''s physical examination showed abdominal distension, absence of bowel sounds and tympanites. The x-ray showed dilated loops, edema between loop and loop and bounden loop. The diagnosis made by clinical feature and abdominal x-ray was intestinal obstruction and intussusception. On 08 October 2008 the subject underwent a surgery in which ileocecocolic intussusception with 5cm length perforation in ileum and mesenteric adenitis was found. Reduction by taxis and intestinal resection of 8 cm length in terminal ileum with anastomosis was performed. The subject''s evolution was bad. Therefore on 15 October 2008 the subject underwent a 2nd surgery in which 50% anastomosis dehiscence and 8mm of new intestinal perforation was found. A new resection of 5 cm in ileum and new anastomosis was performed. The subject showed good evolution. On 27 October 2008 the subject was discharged in good conditions. The subject was treated with (Acetaminophen), Ranitidine, amikacin, metronidazole, midazolam, sodium bicarbonate and cefotaxime. The physician considered the events were possibly related to vaccination with ROTARIX.