Effect of Niclosamide on Basal-Like Breast Cancers
Aldehyde dehydrogenase (ALDH) is a known marker of cancer stem cells. By testing basal-like breast cancer cells for ALDH expression by flow cytometry, investigators were able to isolate a non-adherent population of cells that have high ALDH expression. [Mol Cancer Ther]Abstract

p53: The Barrier to Cancer Stem Cell Formation
The authors address the role of p53 in genomically stable embryonic stem cells, a unique predisposed cancer stem cell model and adult stem cells, its role in the generation of induced pluripotent stem cells, as well as its role as the barrier to cancer stem cell formation. [FEBS Lett]Abstract

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