Symptoms

Extremely itchy bumps or blisters, most often on the elbows, knees, back, and buttocks

The rash is usually the same size and shape on both sides

The rash can look like eczema

Some patients may have scratch marks instead of blisters

Exams and Tests

A skin biopsy and direct immunofluorescence test of the skin are performed in most cases. Your doctor may also recommend a biopsy of the intestines. Blood tests may be ordered to confirm the diagnosis.

Treatment

An antibiotic called dapsone is extremely effective.

A strict gluten-free diet will also be recommended to help control the disease. Sticking to this diet may eliminate the need for medications and prevent later complications.

Immunosuppressive medications may be used, but are less effective.

Outlook (Prognosis)

The disease may be well-controlled with treatment. Without treatment, there may be a significant risk of intestinal cancer.

Possible Complications

Thyroid disease may be found in many patients with dermatitis herpetiformis. Patients are also more likely to develop certain cancers of the intestines.

When to Contact a Medical Professional

Call your health care provider if you have a rash that continues despite home treatment.

Prevention

There is no known prevention of this disease. People with this condition may be able to prevent complications by avoiding foods that contain gluten.

Related MedlinePlus Health Topics

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