Organelle Isolation Using Magnetic Beads

Dynabeads® Magnetic Beads can be used to isolate a number of different organelles and organelle-specific proteins. This magnetic separation technology enables the specific isolation of true fractions in small volumes, and can replace time-consuming and labor-intensive density gradient centrifugations.

Advantages include:

Rapid, high-purity isolations from crude fractions or fractions of common densities

Morphologically intact target organelles can be fixed for EM studies or solubilized directly on the bead surface

Immunomagnetically isolated organelles can be assayed by conventional techniques