Associated products

Applications

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application

Abreviews

Notes

WB

1/10000. Detects a band of approximately 70 kDa (predicted molecular weight: 54 kDa).

ICC

1/250 - 1/500.

IHC-P

1/100.

IP

1/50.

Application notesIs unsuitable for Flow Cyt.

Target

FunctionTranscriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex.