Not so long ago, River North was a collection of run-down warehouses on the fringe of LoDo. Over the past few years, though, this micro ’hood has evolved into a modern hipster hangout dotted with contemporary art galleries, minimalist eateries, and trendy indie music venues.

Eat Grab a seat on the patio at Amerigo Delicatus Restaurant & Market and dig into the New World Italian cuisine. Try the fresh pasta, cheese, and sausage, which are made in-house or locally sourced. 2449 Larimer St., 303-862-9850, amerigodelicatus.com[6]

Drink Last year, Denver’s hip urban winery, the Infinite Monkey Theorem, packed its grapes and relocated from the Art District on Santa Fe. Book a tour or stop in for a can—yes, a can—of wine. 3200 Larimer St. 303-736-8376, theinfinitemonkeytheorem.com[7]

BeautifyAfter one appointment at Rebel Salon, you’ll be swapping cell numbers with one of the chic stylists and booking your next visit via text. Bonus: Admire local paintings on the walls with a glass of wine in your hand. 3358 Larimer St. 303-292-3370, rebelsalondenver.com[8]

Taste Head to Nooch, a quaint vegan market, for staples such as Amy’s dairy-free mac and cheese or offbeat items like gluten-free seasoning for tofu scrambles and vegan jerky. 3360 Larimer St., 720-328-5324, noochveganmarket.com[9]

ListenAlong with the Meadowlark a few doors down, the gritty Larimer Lounge has become a RiNo staple, particularly among music enthusiasts. Check the calendar for standout local acts and national touring groups. 2721 Larimer St., 303-291-1007, larimerlounge.com[10]

ShopClothing retailer MegaFauna is full of funky T-shirts imprinted with sayings such as “America: Back to Back World War Champs.” Don’t miss the cache of creative, locally made jewelry. Our pick: upcycled strappy leather bracelets. 2701 Larimer St., 720-982-8049, megafaunastore.com[11]

SipOne of a few distilleries in the world to use an all-glass still for its distillation process, Mile High Spirits, a newer addition to RiNo, is a must-visit. Try the popular Moscow Mule, which is mixed with the distillery’s smooth Elevate Vodka. 2920 Larimer St., 720-284-9648, drinkmilehighspirits.com[12]

Caffeinate Crema Coffeehouse somehow manages to cater both to java connoisseurs (the cappuccinos are deftly crafted) and to casual passersby (the bright, artsy space is an easy spot to lose yourself in conversation with a couple of friends). 2862 Larimer St., 720-235-2995, cremacoffeehouse.net[13]