Although the Medici banking dynasty may have crumbled with Piero, the family stuck around for a few more centuries

Until their demise in the eighteenth century, the Medici held royal posts as the Dukes of Tuscany.

Catherine de Medici (daughter of Lorenzo II) even became the Queen of France in 1547 when she married King Henry II and was immortalized in Peter Paul Rubens' Medici Cycle (which you can travel to the Louvre and see today).