We accelerate your drug development and neurotoxicity testing

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NEURIX currently standardizes its human and murine neural tissues for the following services: neurotoxicity testing and drug efficacy assessment.
However, collaborations can be initiated for evaluation of our services.

Murine in vitro neural tissues

Complementary to animal experimentation for flexible mechanistic studies as well as compound screening.

Material available in 2D cells or 3D tissues.

Reporter gene constructs for quick analysis of output.

Figure coming soon

Human in vitro neural tissues

NEURIX finalizes the development of healthy in vitro neural tissues as well as disease models.

Read-outs

Possibility to study low concentrations or repeated exposures to compounds.

Combination of methods allow the disambiguation between general cell mechanisms and neural cell mechanisms.

Outline of the strategy for neurotoxicity testing as well as drug-efficacy assessment.Pluripotent stem cells are differentiated into a neural tissue and cultured in a multi-well plate. After acute or chronic exposure to the compound of interest, complementary tests are performed to define different read-outs: general cell parameters and neural/developmental neural parameters. To allow screening of compounds, genetically modified tissues are generated.