The cough provocation test by mechanical stimulation to the cervical trachea with cough quatification by using mask peak flow meter.

Acronym

Quantitive cough provocation test by using mask peak flow meter.

Scientific Title

The cough provocation test by mechanical stimulation to the cervical trachea with cough quatification by using mask peak flow meter.

Scientific Title:Acronym

Quantitive cough provocation test by using mask peak flow meter.

Region

Japan

Condition

Condition

bronchial asthma, cough variant asthma, btonchitis

Classification by specialty

Pneumology

Classification by malignancy

Others

Genomic information

NO

Objectives

Narrative objectives1

To evaluate the utility of cough provocation test by mechanical stimulatuion to the trachea.

Basic objectives2

Others

Basic objectives -Others

Quantification of the cough strength will also be estimated by using mask-peak flow meter.

Trial characteristics_1

Trial characteristics_2

Developmental phase

Not applicable

Assessment

Primary outcomes

Time needed to provoke cough with vibrator before and after the therapy.

Key secondary outcomes

The strength of the provoked cough befroe and after the therapy.

Base

Study type

Interventional

Study design

Basic design

Single arm

Randomization

Non-randomized

Randomization unit

Blinding

Open -no one is blinded

Control

Uncontrolled

Stratification

Dynamic allocation

Institution consideration

Blocking

Concealment

Intervention

No. of arms

1

Purpose of intervention

Diagnosis

Type of intervention

Device,equipment

Interventions/Control_1

The stimulation generated by the vibrator will be applied at the cervilcal trachea up to 2 minutes and time needed to provoke cough will be recorded. The intensity of provoked cough will be estimated by mask peak flow meter.
These measurement will be done before the treatment of the cough and followed after the introduction of the treatment.
Visual analogue scale for cough will be recorded daily and relationship will be estimated.
For the patients with asthma and cough variant asthma, pulmonary function test, ACT score and peak flow will be recorded and relationship will be estimated.

Interventions/Control_2

Interventions/Control_3

Interventions/Control_4

Interventions/Control_5

Interventions/Control_6

Interventions/Control_7

Interventions/Control_8

Interventions/Control_9

Interventions/Control_10

Eligibility

Age-lower limit

18

years-old

<=

Age-upper limit

90

years-old

>=

Gender

Male and Female

Key inclusion criteria

Those with the cough symptoms which supposed to be improved by the treatment, such as bronchial asthma, cough variant asthma, bronchitis.

Key exclusion criteria

# Those with active bleeding from the airway.
# Those with thoracic deformty.
# Those with pneumothorax or thoraco-abdominal surgery prior to the entry to the study.
# Those who are pregnant or during lactation.