Description and Brand Names

Descriptions

Sotalol injection is used to control rapid heartbeats and abnormal heart rhythms that are serious or life-threatening. The injection may also be used when patients are not able to take the oral form.

Sotalol is a beta-blocker and antiarrhythmic. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and at a regular rhythm.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

Solution

Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of sotalol injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

No information is available on the relationship of age to the effects of sotalol injection in elderly patients. However, elderly patients are more likely to have age-related kidney disease, which may require an adjustment in the dose for patients receiving sotalol injection.

Pregnancy

Information about this sotalol-intravenous-route

Pregnancy Category

Explanation

All Trimesters

B

Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Amifampridine

Bepridil

Cisapride

Dronedarone

Fingolimod

Grepafloxacin

Levomethadyl

Mesoridazine

Pimozide

Piperaquine

Saquinavir

Sparfloxacin

Terfenadine

Thioridazine

Ziprasidone

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acecainide

Acetazolamide

Albuterol

Amiloride

Amiodarone

Amisulpride

Amitriptyline

Amoxapine

Anagrelide

Apomorphine

Aprindine

Arformoterol

Aripiprazole

Arsenic Trioxide

Artemether

Asenapine

Astemizole

Azimilide

Azithromycin

Azosemide

Bambuterol

Bedaquiline

Bemetizide

Bendroflumethiazide

Benzthiazide

Bretylium

Bumetanide

Buserelin

Canrenoate

Chloral Hydrate

Chloroquine

Chlorpromazine

Chlorthalidone

Ciprofloxacin

Citalopram

Clarithromycin

Clenbuterol

Clomipramine

Clonidine

Clopamide

Clozapine

Colterol

Crizotinib

Cyclobenzaprine

Cyclothiazide

Dabrafenib

Dasatinib

Degarelix

Delamanid

Desipramine

Deslorelin

Dibenzepin

Diltiazem

Disopyramide

Dofetilide

Dolasetron

Domperidone

Donepezil

Doxepin

Droperidol

Enflurane

Epinephrine

Erythromycin

Escitalopram

Ethacrynic Acid

Etozolin

Fenoldopam

Fenoterol

Fenquizone

Flecainide

Fluconazole

Fluoxetine

Formoterol

Foscarnet

Furosemide

Gatifloxacin

Gemifloxacin

Gonadorelin

Goserelin

Granisetron

Halofantrine

Haloperidol

Halothane

Hexoprenaline

Histrelin

Hydrochlorothiazide

Hydroflumethiazide

Hydroxychloroquine

Ibutilide

Iloperidone

Imipramine

Indacaterol

Indapamide

Isoetharine

Isoflurane

Isradipine

Itraconazole

Ivabradine

Ketoconazole

Lacosamide

Lapatinib

Leuprolide

Levalbuterol

Levofloxacin

Lidoflazine

Lopinavir

Lorcainide

Lumefantrine

Mannitol

Mefloquine

Metaproterenol

Methadone

Metolazone

Metronidazole

Mifepristone

Moricizine

Moxifloxacin

Nafarelin

Nilotinib

Norfloxacin

Nortriptyline

Octreotide

Ofloxacin

Olodaterol

Ondansetron

Paliperidone

Panobinostat

Pasireotide

Pazopanib

Pentamidine

Perflutren Lipid Microsphere

Pirbuterol

Piretanide

Polythiazide

Posaconazole

Prilocaine

Probucol

Procainamide

Procaterol

Prochlorperazine

Promethazine

Propafenone

Protriptyline

Quetiapine

Quinethazone

Quinidine

Quinine

Ranolazine

Reproterol

Risperidone

Ritodrine

Rivastigmine

Salmeterol

Sematilide

Sertindole

Sevoflurane

Sodium Phosphate

Sodium Phosphate, Dibasic

Sodium Phosphate, Monobasic

Solifenacin

Sorafenib

Sotalol

Spiramycin

Spironolactone

Sulfamethoxazole

Sultopride

Sunitinib

Tedisamil

Telavancin

Telithromycin

Terbutaline

Tetrabenazine

Ticrynafen

Tizanidine

Toremifene

Torsemide

Trazodone

Tretoquinol

Triamterene

Trichlormethiazide

Trifluoperazine

Trimethoprim

Trimipramine

Triptorelin

Tulobuterol

Vandetanib

Vardenafil

Vasopressin

Vemurafenib

Verapamil

Vilanterol

Vinflunine

Voriconazole

Xipamide

Zolmitriptan

Zotepine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Abarelix

Acarbose

Aceclofenac

Acemetacin

Acetyldigoxin

Albiglutide

Alfuzosin

Alogliptin

Amlodipine

Amtolmetin Guacil

Arbutamine

Aspirin

Bromfenac

Bufexamac

Bunazosin

Canagliflozin

Celecoxib

Chlorpropamide

Choline Salicylate

Clonixin

Dapagliflozin

Deslanoside

Dexibuprofen

Dexketoprofen

Diclofenac

Diflunisal

Digitoxin

Digoxin

Dipyrone

Doxazosin

Dulaglutide

Empagliflozin

Etodolac

Etofenamate

Etoricoxib

Exenatide

Felbinac

Felodipine

Fenoprofen

Fepradinol

Feprazone

Floctafenine

Flufenamic Acid

Flurbiprofen

Glimepiride

Glipizide

Glyburide

Ibuprofen

Ibuprofen Lysine

Indomethacin

Insulin Aspart, Recombinant

Insulin Degludec

Insulin Detemir

Insulin Glargine, Recombinant

Insulin Glulisine

Insulin Human Inhaled

Insulin Human Isophane (NPH)

Insulin Human Regular

Insulin Lispro, Recombinant

Ketoprofen

Ketorolac

Lacidipine

Lercanidipine

Linagliptin

Liraglutide

Lixisenatide

Lornoxicam

Loxoprofen

Lumiracoxib

Manidipine

Meclofenamate

Mefenamic Acid

Meloxicam

Metformin

Methyldopa

Metildigoxin

Mibefradil

Miglitol

Morniflumate

Moxisylyte

Nabumetone

Naproxen

Nateglinide

Nepafenac

Nicardipine

Nifedipine

Niflumic Acid

Nilvadipine

Nimesulide

Nimodipine

Nisoldipine

Nitrendipine

Oxaprozin

Oxyphenbutazone

Parecoxib

Phenoxybenzamine

Phentolamine

Phenylbutazone

Piketoprofen

Pioglitazone

Piroxicam

Pramlintide

Pranidipine

Prazosin

Proglumetacin

Propionic Acid

Propyphenazone

Proquazone

Repaglinide

Rofecoxib

Rosiglitazone

Salicylic Acid

Salsalate

Saxagliptin

Sitagliptin

Sodium Salicylate

St John's Wort

Sulindac

Tamsulosin

Tenoxicam

Terazosin

Tiaprofenic Acid

Tolazamide

Tolbutamide

Tolfenamic Acid

Tolmetin

Trimazosin

Urapidil

Valdecoxib

Vildagliptin

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

Angina (severe chest pain) or

Heart attack, recent or

Heart disease or

Heart failure, history of or

Hypotension (low blood pressure)—Use with caution. May make these conditions worse.

Asthma or

AV block (type of abnormal heart rhythm), with no pacemaker or

Bradycardia (slow heartbeat) or

Breathing problems or

Cardiogenic shock or

Heart failure, uncontrolled or

Heart rhythm problems (e.g., congenital long QT interval) or

Hypokalemia (low potassium in the blood) or

Hypomagnesemia (low magnesium in the blood) or

Kidney disease, severe or

Sick sinus syndrome (type of abnormal heart rhythm), with no pacemaker—Should not be used in patients with these conditions.

Diabetes or

Hyperthyroidism (overactive thyroid) or

Hypoglycemia (low blood sugar)—Use with caution. May cover up some of the symptoms of these diseases, such as a fast heartbeat.

Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use

A nurse or other trained health professional will give you this medicine in a hospital. This medicine is given through a needle placed in one of your veins.

Tell your doctor or nurse right away if you develop pain or swelling at the site where the needle is placed.

Your doctor will give you a few doses of this medicine until your condition improves, and then switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Precautions

It is very important that your doctor check your progress while you are receiving this medicine to make sure the medicine is working properly. Blood and urine tests may be needed to check for unwanted effects.

Dizziness, lightheadedness, or fainting may occur, especially when you get up suddenly from a lying or sitting position. These symptoms are more likely to occur when you begin using this medicine, or when the dose is increased. Getting up slowly may help.

Sotalol may cause heart failure in some patients. Check with your doctor right away if you are having chest pain or discomfort; dilated neck veins; extreme fatigue; irregular breathing; an irregular heartbeat; shortness of breath; swelling of the face, fingers, feet, or lower legs; weight gain; or wheezing.

This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor or nurse right away if you have a rash; itching; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth while you are receiving this medicine.

This medicine may cause changes in your blood sugar levels. Also, this medicine may cover up signs of low blood sugar, such as a rapid pulse rate. Check with your doctor if you have these problems or if you notice a change in the results of your blood or urine sugar tests.

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Blurred vision

chest pain or discomfort

confusion

difficult or labored breathing

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

fast, irregular, pounding, or racing heartbeat or pulse

increased sweating

shortness of breath

slow or irregular heartbeat

sweating

swelling

tightness in the chest

unusual tiredness or weakness

wheezing

Less common

Arm, back, or jaw pain

body aches or pain

chest tightness or heaviness

chills

cold hands and feet

cough

decreased urine output

diarrhea

difficulty with breathing

difficulty with speaking

dilated neck veins

dizziness

double vision

ear congestion

extreme fatigue

fainting

fever

general feeling of discomfort or illness

headache

inability to move the arms, legs, or facial muscles

inability to speak

irregular breathing

joint pain

loss of appetite

loss of voice

muscle aches and pains

nasal congestion

nausea

nervousness

noisy breathing

pounding in the ears

runny nose

shivering

slow speech

sneezing

sore throat

swelling of the face, fingers, feet, or lower legs

trouble sleeping

troubled breathing

vomiting

weight gain

Incidence not known

Black, tarry stools

bleeding gums

blood in the urine or stools

blue lips and fingernails

coughing that sometimes produces a pink frothy sputum

difficult, fast, or noisy breathing, sometimes with wheezing

increased sweating

painful or difficult urination

pale skin

pinpoint red spots on the skin

sores, ulcers, or white spots on the lips or in the mouth

swelling in the legs and ankles

swollen glands

unusual bleeding or bruising

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

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