Its a slang greeting in New Orleans. When you meet someone in the street they will say that. Then you reply with the key phrase what it is. If you respond wrong, the initiator will know you are not local.

Attempting to follow up on previous email messages which have gone unanswered.

employee: "Jim isn't responding to my email requests to shut down the Hope Creek nuclear power plant before the East shore of New Jersey is a radioactive wasteland."
boss: "Well, remail him. Maybe he's just busy."