PT - JOURNAL ARTICLE
AU - Danchin, Antoine
AU - Ng, Tuen Wai Patrick
AU - TURINICI, Gabriel
TI - A new transmission route for the propagation of the SARS-CoV-2 coronavirus
AID - 10.1101/2020.02.14.20022939
DP - 2020 Jan 01
TA - medRxiv
PG - 2020.02.14.20022939
4099 - http://medrxiv.org/content/early/2020/02/18/2020.02.14.20022939.short
4100 - http://medrxiv.org/content/early/2020/02/18/2020.02.14.20022939.full
AB - We explore here how variation in the SARS-CoV-2 virus tropism could influence epidemic spread. We use a compartmental model fit to the existing data. The model indicates that Wuhan quarantine measures were effective but that alternative virus forms (gut tropism) and a second propagation route (through environment) was present. For Singapore and Shenzhen region the secondary route does not seem to be active yet. Adequate prevention measures taking into account both routes should be implemented.Competing Interest StatementAD is employed by Stellate Therapeutics (fka Amabiotics), a company that works on treatment of neurodegenerative diseases.Funding StatementAuthors were funded by their respective employers.Author DeclarationsAll relevant ethical guidelines have been followed; any necessary IRB and/or ethics committee approvals have been obtained and details of the IRB/oversight body are included in the manuscript.YesAll necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived.YesI understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).Yes I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable.Yesno personal of private data were used in this work.