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Alexis Hamel went to the University of London as a young aspiring art student from Miami, Florida, but left London as Jacqulyn Hennessey, a newly transformed mutant with a toxic venom that coursed through her veins. She had been the subject of a mutant experiment by one Dr. Nikolas Alexander, a mutant himself, who missed the art of mischief. Along with his best friend and lover, Liam Gallagher, they capture and subdue Alexis, making her the first man made mutant. A warlock, Cole Forrester aids them in their experiment and falls madly in love with his venomous subject. Although he knows it is wrong to keep her there, Cole makes no attempts to help her escape her fate as Nikolas' private hit woman. After hearing of her rape by Nikolas, Cole takes matters into his own hands, fleeing with the woman he loves and leaving Nikolas to burn in his own hell.