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Celine Dion’s dream to become a mother for a second time has suffered a major setback. Rene Angelil, her husband, revealed that she is no longer pregnant as the latest in vitro fertilization treatment she underwent was unsuccessful.

Hello! Magazine quoted him as telling the Canadian newspaper Journal de Montreal during a telephone interview from the couple’s Florida home,

We’re living the reality of the majority of couples who face these procreation techniques. The road can be long and difficult. It doesn’t always work as was the case the first time with Rene-Charles.