OMFGItsJackAndDean are 2 students (Jack Howard and Dean Dobbs) who make videos on YouTube. The majority of their videos are sketches and vlogs. The videos they are most well known for are "Pronunciation Frustration" and "Harry Potter and the Logical Situation". Both Howard and Dobbs have acted in other YouTubers videos, such as TomSka, Slomozovo, EddsWorld, and more.

You: Snoop dog tried to add me on fac-e-book last night
Friend: Why did you say it like that?
You: Its an OMFGItsJackAndDean joke.