Marko-Lam Deoxygenation

General Characteristics

The deoxygenation of alcohols via p-toluic acid esters under single-electron reduction conditions is known as the Marko-Lam deoxygenation.

It has advantages over the Barton-McCombie deoxygenation, including higher stability of the precursors, faster and milder reaction conditions, and unnecessity of toxic (and difficult to remove) organic tin reagents.