Seth Meyers took a closer look at President Obama's historic visit to Cuba on "Late Night with Seth Meyers" on March 22. Photo: NBC

Seth Meyers gives President Obama credit for trying a new strategy to reconnect Cuba to the rest of the world and improve the human rights situation in that country. But the comedian and host of NBC's "Late Night with Seth Meyers" couldn't resist poking fun at some of the more awkward moments of the president's historic visit to Cuba.

Meyers used his "Closer Look" segment on his show Tuesday to break down Obama's trip to Havana. The comedian noted that Obama did not fly solo but brought with him representatives from American companies looking to gain a footing in Cuba now that economic ties have been renewed. Among the business leaders accompanying Obama were representatives from many major hotel chains, including Airbnb co-founder Brian Chesky, Marriott CEO Arne Sorenson, Major League Baseball Commissioner Rob Manfred and Starwood Hotels general counsel Ken Siegel.

"I apologize in advance, Cuba, because once you got hotels it's only a matter of time before you are inundated with drunk, American college kids on Spring Break, and that is the real Bay of Pigs," joked Meyers.

Meyers went on to make fun of Obama's joint press conference with Cuban President Raúl Castro on Monday. At the end of a press conference that featured an uncomfortable exchange on human rights — Obama called on Castro to expand freedoms in the country, while Castro denied that Cuba holds political prisoners — the two world leaders shared an awkward handshake when Castro held up Obama's seemingly limp arm.

"That is the handshake of a man who does not want a photo taken," said Meyers, theorizing that Obama wanted to spoil the photo op after drawing criticism for posing in front of a mural of Cuban revolutionary Che Guevara earlier that day. Meyers joked that the photo marked "an implicit endorsement of Urban Outfitters," a reference to the department chain's trendy, provocative clothing.