Green Bay at Buffalo

Time: 1 p.m. Line: Packers by 4½.

Records: Packers 10-3 (6-7 vs. spread), Bills 7-6 (7-6 vs. spread).

Comments: Bills’ Sammy Watkins leads AFC rookies with 822 receiving yards and is second with 58 catches and five TDs . . . Jordy Nelson (12), Eddie Lacy (11), and Randall Cobb (10) are first Packers trio with 10-plus TDs in a season . . . Nelson has 12 TDs in his last 14 games vs. AFC . . . Green Bay has won five straight (sorry, Patriot Nation) and nine of last 10 . . . Buffalo has an NFL-high 48 sacks and Marcell Dareus leads all DTs with 10 . . . Packers lead NFL with 423 points . . . Bills graybeard Fred Jackson had career-high 10 catches last week . . . Player to watch: Lacy has collected 100-plus yards from scrimmage in six straight games and has 773 yards and seven TDs during that run.

Comments: Broncos beat Chargers, 35-21, in Week 8 and lead series, 59-49-1 . . . Denver’s Peyton Manning was held without a TD pass against the Bills last week, ending his streak of games with a TD pass at 51. That was second longest behind Drew Brees’s 54 . . . Manning is 5-1 vs. Chargers as Broncos QB . . . San Diego’s Ryan Mathews is averaging 100.5 scrimmage yards in last six division games . . . Chargers QB Philip Rivers has thrown for 636 yards and six TDs in last three in this rivalry . . . Denver’s Demaryius Thomas has 1,125 receiving yards and nine TDs in last 10 games . . . Player to watch: Broncos’ C.J. Anderson is averaging 143.2 yards from scrimmage and has six TDs in his last five games.

Houston at Indianapolis

Time: 1 p.m. Line: Colts by 6½.

Records: Texans 7-6 (8-5 vs. spread), Colts 9-4 (9-4 vs. spread).

Comments: Colts beat Texans, 33-28, in Week 6 and lead series, 21-4 . . . Indianapolis’s Andrew Luck’s 12,501 passing yards are most in first three seasons of any Super Bowl-era QB (Peyton Manning 12,287) . . . Houston QB Ryan Fitzpatrick has thrown for 1,397 yards, 12 TDs, and 2 INTs in his last six games . . . Texans WR Andre Johnson is four catches shy of 1,000 for his career . . . Player to watch: Colts WR T.Y. Hilton has collected 62 catches for 1,109 yards and seven TDs in his last 10 games.

Cincinnati at Cleveland

Time: 1 p.m. Line: Browns by 1.

Records: Bengals 8-4-1 (6-7 vs. spread), Browns 7-6 (8-5 vs. spread).

Comments: Browns beat Bengals, 24-3, in Week 10, with Brian Hoyer at the helm. In rematch, rookie QB Johnny Manziel will make his first NFL start . . . Andy Dalton is 38-22-1 (.631), the highest winning percentage of any Bengals QB with at least 20 starts . . . Cleveland CB Joe Haden has a pick in three of last four games . . . Safety Donte Whitner leads the Brownies with 85 tackles . . . Player to watch: WR A.J. Green caught 11 passes for a career-high 224 yards last week — second most in franchise annals.

Pittsburgh at Atlanta

Time: 1 p.m. Line: Steelers by 1½.

Records: Steelers 8-5 (6-7 vs. spread), Falcons 5-8 (7-6 vs. spread).

Comments: Steelers RB Le’Veon Bell leads the AFC with 1,924 yards from scrimmage and joined the great Walter Payton (Sweetness!) as the only players NFL history with 200-plus scrimmage yards in three straight games . . . Atlanta QB Matty “Ice” Ryan is 39-12 inside the Georgia Dome with 84 TDs and a 98 passer rating . . . Pittsburgh’s Big Ben Roethlisberger has thrown for 2,462 yards and 21 TDs in his past seven games . . . Player to watch: Falcons safety Kemal Ishmael (that’s what they call him) has a pick in three of past five games.

NY Jets at Tennessee

Time: 4:05 p.m. Line: Jets by 2½.

Records: Jets 2-11 (4-8-1 vs. spread), Titans 2-11 (3-10 vs. spread).

Comments: It’d be great if the Jets wore their old New York Titans unis for this one . . . Jets RB Chris Johnson rushed for 7,965 yards and 50 TDs in six seasons with Titans . . . Chris Ivory leads Jets with 714 rushing yards . . . Tennessee QB Jake Locker threw for 149 yards and three TDs in win over Jets last season . . . New York DT Sheldon Richardson had a career-high three sacks and a safety last week . . . Player to watch: Titans rookie RB Bishop Sankey has collected 50-plus total yards in six of last eight games.

Comments: Miami beat New England, 33-20, in Week 1 . . . Dolphins lead series, 51-44, including the past two . . . Patriots have won at least 10 games in 12 straight seasons . . . Rob Gronkowski needs 3 receiving yards for second-career 1,000-yard campaign . . . Miami DE Cameron Wake has 7½ sacks in his last nine games . . . Patriots DE Rob Ninkovich has six sacks in his past eight games . . . Since becoming a Dolphin last season, Brent Grimes leads AFC corners with nine INTs . . . Tom Brady passed Miami legend Dan Marino for third all time with his 64th 300-yard passing game last week in San Diego . . . Player to watch: Miami’s Ryan Tannehill has thrown for 2,420 yards, 17 TDs, and 7 INTs over his last 10 games.