Objective
The aim was to investigate the diagnostic potential of dual-time-point 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in patients with breast cancer with known or suspected liver metastases and to assess its clinical value on clinical management.
Patients and methods
A total of 151 consecutive patients with breast cancer who underwent 18F-FDG PET/CT scan for staging or restaging, in whom an additional delayed scan of the liver was performed, were retrospectively evaluated.
Results
Overall, 18F-FDG PET/CT showed the presence of 146 liver metastases in 57 patients. ...

AbstractBackgroundRoughly 23% of breast conserving surgery (BCS) patients undergo a second re-excision procedure due to pathologically positive surgical margins. We investigated the feasibility and potential value of micro-Computed Tomography (micro-CT) as a surgical margin guidance tool during BCS.MethodsA cohort of 32 BCS specimens was prospectively imaged with a pre-clinical micro-CT system upon arrival in the surgical pathology laboratory. Reconstructed micro-CT scans were evaluated retrospectively by an experienced breast radiologist, who provided binary determinations whether lesions extended to the specimen margin. ...

CONCLUSIONS: Our study demonstrates that the vast majority of ARM nodes (72%) are outside the tangential whole breast radiotherapy fields. In our study, all the ARM nodes were within the axillary radiotherapy fields covering level 1-4 axillary volumes according to the ESTRO contouring guideline, and complete shielding of the humeral head according to the EORTC consensus did not lead to sparing of the ARM nodes. A prospective study is needed to examine the oncological safety of ARM node-sparing axillary radiotherapy and its potential to reduce the risk of arm lymphoedema.
PMID: 30446320 [PubMed - as supplied by publisher]

Authors: Sarikaya I, Sarikaya A
Abstract
Objective: Fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) has limited value in early breast cancer. Sentinel lymph node (SLN) biopsy is the current procedure of choice to search for small metastatic deposits in the axillary lymph nodes in early breast cancer. In this retrospective study, we re-evaluated 18F-FDG PET/CT images after locating SLN(s) on PET/CT with the help of SLN single photon emission computed tomography/computed tomography (SPECT/CT) images and assessed 18F-FDG uptake particularly in the SLN(s). Our goal was...

Authors: Hernández Pardines F, Serra Verdú MC, Bernal Vidal A, Mayol Belda JM, Mengual Verdú E
Abstract
The case concerns a 58 year-old female with no medical history of interest who consulted due to binocular diplopia of one week onset. It was associated with costal pain, dyspnoea, intense asthenia and weight loss of 2 months onset. In the blood analysis in the Emergency Department it showed hypercalcaemia, renal failure, and bicytopenia. The chest x-ray showed lytic bone lesions that initially lead to multiple myeloma with extra-osseous involvement. In addition to the corresponding study, in ...

Conclusion: Certain MRI features of TNBC such as heterogeneous or rim enhancement, intratumoral very high signal intensity on T2 images, and peritumoral edema might be useful in predicting the prognosis of patients with TNBC.Oncol Res Treat

AbstractBackground.Intratumoral heterogeneity of 18F‐fluorodeoxyglucose (18F‐FDG) uptake in primary tumor has proven to be a surrogate marker for predicting treatment outcome in various tumors. However, the value of intraindividual heterogeneity in metastatic diseases remains unknown. The aim of this study was to evaluate pretreatment positron emission tomography/computed tomography (PET/CT) 18F‐FDG‐based heterogeneity for the prediction of first‐line treatment outcome in metastatic triple‐negative breast cancer (mTNBC).Materials and Methods.mTNBC patients from three clinical trials (NCT00601159, NCT01287624, a...