Many people did not like the marriage. It did not bring money and very little other benefits. Richard gave 20,000 florins (around £4,000,000 in today's value) in payment to her brother Wenceslas. The only benefit, which was said to be small, was that England could trade freely in both Bohemian lands, and lands of the Holy Roman Empire.

They were married for 12 years, but had no children. Anne's death from plague in 1394 at Sheen Manor was hard for Richard. His later unwise conduct lost him the throne.[3] Richard married his second wife, Isabella of Valois, on 31 October 1396.

Anne of Bohemia is known to have made the sidesaddle more popular to ladies of the Middle Ages.