1,852 Possible Causes for HISTONES

Thus they are called anti-histone antibodies. Anti-histone antibodies may be seen in both systemic lupus erythematosus and drug-induced lupus.[clinicaladvisor.com]The antihistone antibodies in DIL primarily form against a complex of the histone dimer H2A-H2B, which is in contrast to idiopathic SLE in which complexes are formed against[uspharmacist.com]Anti-histone antibodies are often ordered to diagnosis DIL. However, they are positive in systemic lupus erythematosus at the same rates (75%).[clinicaladvisor.com]

Clinically, high circulating levels of histones and histone-DNA complexes are associated with multiorgan failure, DIC, and adverse patient outcomes.[ncbi.nlm.nih.gov]KEYWORDS: Platelets; anticoagulation; coagulation; disseminated intravascular coagulation; histones[ncbi.nlm.nih.gov]Recent observations have pointed to an important role for extracellular DNA and DNA-binding proteins, such as histones, in the pathogenesis of DIC.[ncbi.nlm.nih.gov]

We show changes in histone H3 acetylation occur during arsenical-induced malignant transformation that are linked to the expression state of the associated gene.[ncbi.nlm.nih.gov]This WNT5A transcriptional activation is correlated with the enrichment of permissive histone modifications and the reduction of repressive modifications in the WNT5A promoter[ncbi.nlm.nih.gov]We evaluated the potential epigenetic component of arsenical action by assessing the histone acetylation state of 13 000 human gene promoters in a cell line model of arsenical-mediated[ncbi.nlm.nih.gov]

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