Borrowed into English in the nineteenth century, apparently from several sources. Many borrowings are of RussianНи́на(Nína), the name of a Georgian fourth century saint, also known as Nino, of obscure origin and meaning, possibly connected with the Assyrian king Ninus. Others are of an Italian short form of diminutives like Annina from Anna and Giovannina from Giovanna.

Phonologically or orthographically similar names are present in several languages, including Afrikaans, Hindi, Italian, Persian, Romanian, Russian, Spanish and some Native American languages. In many of those, it is a nickname for names ending in -ina or -nina.

The first three, Macklin, Lydia, and Randall, were the special ones. Even those names, we thought, showed greater imagination, greater involvement on our parents' part, than ours did: Nina, Mary, Sarah. Clearly by that time they had run out of gas.