Key Matchup: Giants CB William Peterson vs. Cowboys QB Quincy Carter. Peterson has come up with INTs to end opponents' late-game drives in both Giants wins. Carter has thrown only three INTs in four games. Carter threw for 204 yards with one TD and one INT last week.

Key Matchup: Buccaneers LB Derrick Brooks vs. Falcons QB Michael Vick. Brooks has three INTs this season (tied for best in NFL), two of which he returned for TDs. Vick has not thrown an INT and has best QB rating in NFC. Brooks will look to keep Vick in pocket, because Vick leads NFL QBs in yards rushing with 184.

Key Matchup: Cardinals RB Marcel Shipp vs. Panthers DE Julius Peppers. Last week, Shipp had a career-high 92 yards rushing, including first career TD run. Peppers, No. 2 pick in NFL draft, had breakout game in Week 2 with three sacks and four solo tackles against Lions.

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Washington (1-2) at Tennessee (1-3)

Time: Noon

Last Week: Redskins had bye, lost to 49ers 20-10 in Week 3; Titans lost to Raiders 52-25.

Key Matchup: Bengals offense vs. Colts K Mike Vanderjagt. In four games this season, the Bengals have scored one offensive TD, a 22-yard TD reception by WR Chad Johnson in Week 2 against Cleveland. In only three games, Vanderjagt has scored 22 points, one shy of Bengals' total, on five FGs and seven PATs.

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Pittsburgh (1-2) at New Orleans (3-1)

Time: Noon

Last Week: Steelers beat Browns 16-13 in OT; Saints lost to Lions 26-21.

Key Matchup: Steelers LB Joey Porter vs. Saints QB Aaron Brooks. Porter is tied for NFL lead with three INTs and has three sacks. Brooks has thrown nine TD passes, tied for best in NFC, but has also thrown six INTs, tied for third worst in NFL. Porter and Steelers also must respect Brooks' ability to run  he has 99 yards and TD on ground.

Key Matchup: Chiefs coach Dick Vermeil vs. Jets coach Herman Edwards. Edwards played DB for Vermeil with Eagles from 1977-82. Edwards' Jets have managed to score only 13 points in past three games and have gone nine quarters without TD. Vermeil's Chiefs scored 17 points in the fourth quarter alone last week, and could feast on Jets' overworked defense.

Key Matchup: Chargers LT Vaughn Parker vs. Broncos DE Trevor Pryce. Pryce, a second-team All-Pro last year at tackle, anchors Denver's defensive line, which is allowing a paltry 56.5 yards rushing per game. Parker has been clearing holes for RB LaDainian Tomlinson, the NFL's leading rusher with 506 yards in four games, including 217 yards and two TDs against Patriots.

Key Matchup: Eagles QB Donovan McNabb vs. Jaguars' pass rush. Despite his speed, McNabb has been sacked 14 times, tied for third most in NFL. Jaguars have managed only four sacks in three games. To win, they will need to pressure McNabb, who ranks in top five in three passing categories.

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St. Louis (0-4) at San Francisco (2-1)

Time: 3:15 p.m.

Last Week: Rams lost to Cowboys 13-10; 49ers had bye, beat Redskins 20-10 in Week 3.

Key Matchup: Rams RB Marshall Faulk vs. 49ers defense. Faulk has rushed for 100 yards in three of past five games against 49ers. He will have to carry the bulk of offense with QB Kurt Warner out with broken finger. 49ers have NFL's seventh-ranked defense and will build game plan around stopping Faulk.

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Baltimore (1-2) at Cleveland (2-2)

Time: 7:30 p.m., ESPN

Last Week: Ravens beat Broncos 34-23; Browns lost to Steelers 16-13 in OT.

Key Matchup: Ravens LB Ray Lewis vs. Browns QB Tim Couch. Lewis, an All-Pro last season, is one of game's top defenders, ranking second in tackles. In five games against Ravens, Couch has been limited to 72-of-136 passing for 676 yards, three TDs and eight INTs  a 49.8 QB rating. If Couch's line doesn't give him time to throw, Lewis will feast on Browns QB.

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Monday

Green Bay (3-1) at Chicago (2-2)

Time: 8 p.m., ABC

Last Week: Packers beat Panthers 17-14; Bears lost to Bills 33-27 in OT.

Key Matchup: Packers CBs Mike McKenzie and Tyrone Williams vs. Bears WR Marty Booker. McKenzie has two INTs this season and Packers have six, tied for third best in league. Booker is NFL's leading receiver with 425 yards and has led Chicago in receiving in six of last seven games.