Malignant Liver Tumors

The liver (Latin: Iecur, Greek: Hepar) is the generalist among all organs – acting universally as center of metabolism, storage unit, detoxifying- and excreting organ. Medical staff is frequently confronted with diseases such as liver cirrhosis, hepatitis and fatty liver. Therefore, anatomical and biochemical knowledge of the liver is part of every medicine student`s basic training. Read this compact overview on structure, functions and diseases of the liver.

Liver tumors are some of the more common neoplasms and are classified as either primary or secondary. Management varies depending on several factors such as type, size, and the spread of the cancer. Continue to read this article to learn key facts about the tumors of the liver including incidence, pathology, clinical features, diagnosis, and treatment.

00:01
Hepatocellular carcinoma (HCC)A specific tumor within the liver.
00:06
Anything that causes cirrhosis,any cause of cirrhosis,you're at risk for HCC.
00:13
So, alcohol, sure.
00:17
Non alcohol, yes.
00:18
Give me two major differentials of
non-alcoholic issues.
00:23
Autoimmune or maybe perhaps NASH.
00:26
Continue...
00:27
What about autoimmune?
What about Hemochromatosis?What about a wholeholes of differentialsthat may result in cirrhosis.
00:35
Hepatitis C.
00:39
Imaging sufficient with
background cirrhosis.
00:42
And that background cirrhosis
means what to you?Where fibrosis kicking in,tell me the size of the liverversus the original size,shrunken.
00:52
Biopsy, not always useful.
00:54
Imaging is sometimes sufficient.
00:57
Here, with the Hepatocellular carcinoma,
expect her to be increased inalpha-fetoprotein.
01:02
Metastasis to the lung, bone and brain.
01:07
So this is a primary Hepatocellular carcinomathat may have resulted, let's say,
from cirrhosisand from the liver.
01:15
It might metastasis,go up to the lung,and then near
the bone and near the brain.
01:20
Important areas of Metastasis.
01:22
The treatment. Obviously, resection.
01:25
Transplantation is high
on that list.
01:28
You have chemo-embolization.
01:29
Maybe percutaneous,ablation, and we have
sorafenib.
01:36
Metastasis.
01:38
Just like many the cancers
we have discussed,at times the most common cancer
of that particular organ would beMetastasis from a primary.
01:47
That is the topic for this section.
01:50
Most frequent site of metastasisis from the GI tract,limited role of the resection in case of
Colorectal Cancer (CRC).
01:58
In Colorectal cancer,you need to make sure, you
always check to see is to whether notit is then Metastasized.
02:04
With Colorectal cancer,
our discussion earlieris when we looked at duke classification.

USMLE™ is a joint program of the Federation of State Medical Boards
(FSMB®) and National Board of Medical Examiners (NBME®). MCAT is a registered
trademark of the Association of American Medical Colleges (AAMC).
None of the trademark holders are endorsed by nor affiliated with Lecturio.