Definition of BP1

BP1: Beta protein 1, a protein encoded by a member of the homeobox gene family, a group of genes important to early development of the fetus. Specifically, BP1 belongs to the DLX homeobox family. BP1 acts as a transcription factor that turns other genes on and off and regulates the beta globin gene. BP1 is overexpressed in a large proportion of cases of acute myeloid leukemia (AML) and breast cancer.