At UFC 200, Velasquez defeating Travis Browne by first round TKO, and was dominant along the way, leading many to believe another title run could be on it's way.

Velasquez won the UFC Heavyweight Title the first time at UFC 121 when he defeated Brock Lesnar by first round TKO. The heavyweight would lose the belt in his first defense at UFC On Fox 1, but then got it back by defeating Junior Dos Santos in a rematch at UFC 155.

Cain has only competed twice in the last three years and nearly half of his UFC appearances have been main event fights.