Discover ReFissa | What to Expect Month-by-Month

Month 1

As ReFissa begins to work, it may produce redness, flaking and irritation.
Many people find that the signs of irritation end after a couple of months.
If your skin becomes too irritated, consult with your doctor, who may
suggest you try using it every other night. Then resume nightly treatment
when you can. Remember, ReFissa works gradually. You may not see
full results until the 24th week. See the clinical data.

Month 2

You may notice that your skin is smoother and has a softer texture.7

Month 3-4

Irregular pigmentation may begin to lighten, while fine facial wrinkles
may begin to diminish. You may see and feel an overall improvement
in the texture and appearance of your skin.7

Month 5-6

You may continue to see and feel your skin texture and skin tone improve.7

Month 6+

To maintain the results of ReFissa, continue to use it nightly. And since
tretinoin, the active ingredient, may make your skin more sensitive to
the sun, it's also important to practice sun protection and use sunscreen with SPF 15 or higher during the day.