This is where the real business starts in the Champions League and going into the 1st knockout round the bookies have Barcelona the favourites at a best priced 3/1 with Sky Bet, the leaders of La Liga have a difficult tie though taking on French League leaders Lyon. Defending champions Manchester United also have a difficult tie to negotiate against Jose Mourinho’s Inter Milan probally going some way to explaining why their odds are as high as 11/2 with Stan James. The only other side in single figure odds are Chelsea and then come the likes of Liverpool, Arsenal, Real Madrid, Bayern Munich and Juventus all with an outside chance at attractive double figure prices.

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