The Chosen One

The Chosen One was a prophecy by Milo Rambaldi found on Page 47 that stated that whoever the Chosen One was, would bring forth Rambaldi's works and bring about complete destruction. Most consider Sydney Bristow to be The Chosen One, who was born hundreds of years after the prophecy was made.

This woman here depicted will possess unseen marks, signs that she will be the one to bring forth my works: bind them with fury, a burning anger. Unless prevented, at vulgar cost, this woman will render the greatest power unto utter desolation. This woman, without pretense, will have had her effect, never having seen the beauty of my sky behind Mt. Subasio. Perhaps a single glance would have quelled her fire.

Sydney Bristow tried to disprove that the prophecy refers to herself by climbing Mt. Subasio, however, this was later confirmed to be a misinterpretation of the meaning of the prophecy as the "beauty of my sky behind Mt. Subasio" referred to what Sloane saw in the cavern using the amulet recovered from "The Rose" and prevented Sydney from seeing.

After Sydney removed the chances of her being 'The Chosen One' by visiting Mt. Subasio, the DSR refocused their efforts on trying to track down Derevko who they then believed to be The Chosen One after it was revealed she was still alive and would also resemble the person described in the manuscript and in the picture due to her being Sydney's mother.