Share On:

I don't think it's that easy. It still might be related to down-regulated receptors but there is probably some chronic hormone inhibition or something that's causes them to stay screwed up. I think the cause of PSSD has sorta been known for a while but it needs to be pin pointed. The fact that most people that have normal blood tests points towards this being local to the brain only. In other words: neuro steroids. Even if the changes are epigenetic,(which is most likely) it might still be able to be made up for through some kind of hormonal treatment.

PSSD Since March 2016 after 4 weeks on SertralineConditioned worsened and peaked in April, since then possibly seen a 20% improvementWould be useful for data collection if people could add their histories in their signature

Clearly PSSD disproportionately affects men. What can we infer from this?

Is a woman's serotonin system different from a man's such that it would account for this? I don't know shit, but I would assume not. So isnt this pretty strong evidence of specific hormones being the relevant factor?

anxietor wrote:Clearly PSSD disproportionately affects men. What can we infer from this?

Is a woman's serotonin system different from a man's such that it would account for this? I don't know shit, but I would assume not. So isnt this pretty strong evidence of specific hormones being the relevant factor?

This is what I'm going with. You'll hear arguments about the social differences of sex amongst males and females and that females are equally affected but less likely to care. I don't buy it. We know PSSD affects more than just the sexual organs and libido. I think this is a major clue pointing to the endocrine system.

anxietor wrote:Clearly PSSD disproportionately affects men. What can we infer from this?

Is a woman's serotonin system different from a man's such that it would account for this? I don't know shit, but I would assume not. So isnt this pretty strong evidence of specific hormones being the relevant factor?

This is what I'm going with. You'll hear arguments about the social differences of sex amongst males and females and that females are equally affected but less likely to care. I don't buy it. We know PSSD affects more than just the sexual organs and libido. I think this is a major clue pointing to the endocrine system.

It makes so much sense. You can probably mess with DHT and progesterone in women without causing devastating effects(I'm assuming). But we know that messing with these hormones in men can end in disaster.

Edit: I mean, progesterone levels in women naturally rise and fall without creating sexual dysfunction, so getting an extra boost from SSRIs might not matter as much as with men. Women already have very low DHT levels, so I doubt lowering DHT in women would cause too many problems.

anxietor wrote:Clearly PSSD disproportionately affects men. What can we infer from this?

Is a woman's serotonin system different from a man's such that it would account for this? I don't know shit, but I would assume not. So isnt this pretty strong evidence of specific hormones being the relevant factor?

This is what I'm going with. You'll hear arguments about the social differences of sex amongst males and females and that females are equally affected but less likely to care. I don't buy it. We know PSSD affects more than just the sexual organs and libido. I think this is a major clue pointing to the endocrine system.

It makes so much sense. You can probably mess with DHT and progesterone in women without causing devastating effects(I'm assuming). But we know that messing with these hormones in men can end in disaster.

Edit: I mean, progesterone levels in women naturally rise and fall without creating sexual dysfunction, so getting an extra boost from SSRIs might not matter as much as with men. Women already have very low DHT levels, so I doubt lowering DHT in women would cause too many problems.

The pill (which affects progesterone) is known to cause sexual dysfunction in some women. I am also sure there are more women with PSSD than we now think, but it is more obvious for men due to ED. Im sure plenty women just think they are depressed, while it's really PSSD.

First post: so true about women. It especially doesn't help that our doctors suggest that to be a reason for our low sex drive. I explained my issues a doctor and she suggested I was nearly depressed. Because apartmently depression can cause your genitals to feel numb, right.