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Effects of environmental pollutants in germfree rodents.

Authors

Pollard-M

Source

Terminal Progress Report 1974 Dec; :1-3

Link

NIOSHTIC No.

00047710

Abstract

Tissues from rats exposed to coal dust are examined histopathologically. The lesions are confined to the lungs as clearly-defined granulomas in the parenchyma of the lungs, but not complicated by bacterial agents. Results indicate that the reactions induced in the germfree rats by inhalation of coal and quartz dusts are more clearly defined than by use of conventional animals, and that they would be valuable in quantitative studies on environmental pollutants.