Richard Evans Schultes—ethnobotanist, taxonomist, writer, photographer, and Harvard professor—is regarded as one of the most important plant explorers of the twentieth century. In 1941, Schultes traveled to the Amazon rainforest on a mission to study how Indigenous peoples used plants for medicinal, ritual, and practical purposes. A new interactive online map, produced by the Amazon Conservation Team, traces the landscapes and cultures that Schultes explored in the Colombian Amazon. Plotkin and Hettler will share this map and discuss the relevance of Schultes’ travels and collections for science, conservation, and education in the twenty-first century.