What does it take to win the Kentucky Derby? Hosts Gary O’Reilly and Chuck Nice explore thoroughbred genetics and the ins and outs of horse racing with Dr. Stephen Harrison from Thoroughbred Genetics and former champion steeplechase jockey Sean Clancy.

What does it take to be World Champion? How can women’s boxing gain more popularity? Can you be a fighter and a trainer? Hosts Chuck Nice and Gary O’Reilly step into the ring with World Champion Alicia Ashley, astrophysicist and boxer Federica Bianco, and former Olympic-style boxer Cary Williams.

Hosts Gary O’Reilly and Chuck Nice investigate “HomerGate” with baseball data scientist and astrophysicist Meredith Wills, and find out what it takes to be a groundbreaker in sports from Justine Siegal, the first female coach in the MLB.

What’s the best wrestling move? Can you wrestle in zero gravity? Hosts Gary O’Reilly and Chuck Nice hit the mats as we sit down with astrophysicist and wrestling expert Neil deGrasse Tyson to answer fan-submitted questions about the science of wrestling

We dive into the expanding world of Esports as hosts Chuck Nice and Gary O’Reilly get the science behind the screen from Nicholas “NicoThePico” Korsgård, head coach of “League of Legends” pro team PostFinance Helix, and neuroscientist Heather Berlin, PhD.