Masivukeni, which translates to 'Let's wake up!' in the Xhosa language, is a computer-supported curriculum designed to help patients in South Africa stay on their antiretroviral medication. Masivukeni provides lay counselors with an intervention roadmap and scripts that help them communicate to their patients the importance of adherence to treatment plans. In addition, the Masivukeni tool features interactive activities to help patients build their support network, develop problem-solving skills, visualize their pill regimen, and learn how HIV affects the body as viral resistance develops.

Masivukeni is a collaboration between Dr. Robert Remien, a research scientist at the HIV Center for Clinical and Behavioral Studies; researchers at the University of Cape Town; and CCNMTL. It was developed with assistance from counselors, nurses, and volunteers at the Hout Bay clinic outside of Cape Town, South Africa. The project is supported by a five-year, $3 million grant from the National Institute of Mental Health (NIMH) and builds on a 2007 NIMH grant that facilitated developing and piloting Masivukeni. Masivukeni is now being tested in a randomized control trial at two clinics outside Cape Town, South Africa.