A prospective study was performed to gauge the outcomes of a newer and modified approach to the surgical management and treatment of post-traumatic lower extremity end neuroma formation experienced by patients. Chronic peripheral nerve pain of the lower extremity that presents after a traumatic episode or post-surgical procedures continues to be a major concern for physicians and is affecting patients worldwide. This article will demonstrate a unique approach that was utilized in two different patients that suffered from severe peripheral nerve pain due to end-neuroma development involving the deep peroneal nerve (DPN). Patient success was measured based on the extent of pain relief after surgery, the ability to walk, and the duration of time it took for each patient to return to work.