"Dear Ivanka, you follow me on social media," the Instagram letters begin. "You said family separation was a 'low point' for you. The low point is for the separated families."

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Trump last week referred to the separation of more than 2,000 migrant children from their parents as a "low point" of her time in the White House. The children were separated as a result of the administration's "zero tolerance" immigration policy.

At the time, she took flak over her silence on the issue, despite promoting herself as a mother fighting for family rights in the public eye.

The administration has scrambled for weeks to reunite children with their families following a federal court order, but hundreds remain separated.

"As of now, 572 children had not been reunited," continues the Instagram letter, which has been shared widely. "Approximately 400 parents have been deported without their children. There have been multiple claims of sexual and physical abuse in detention.

"There have been multiple claims of psychotropic drugs administered to children in detention without parental consent.

"End these racist, inhumane and unconscionable abuses now!" the letter concludes. "We demand you call for the resignation of Secretary Nielsen!"

The same celebrities launched a campaign directed toward Trump last year in response to the president's announcement that he would rescind the Deferred Action for Childhood Arrivals (DACA) program, a policy that extends certain protections to people brought to the U.S. as children.