Fig. 3

LATS1/2 total protein decreases in response to MTX/DOX treatment in osteosarcoma cells. a Grayscale comparisons of LATS2 total protein to that of GAPDH in U2OS cells, according to the western blotting results in Fig. 2c, d. The error bars represent mean ± SD. Compared with control (t test, n = 3), *P < 0.05 and #P < 0.05. LATS2 protein level was decreased by MTX and DOX in U2OS cells. b Representative image of LATS1 total protein in MG63 cells treated with indicated concentrations of MTX or DOX. LATS1 protein level was decreased by MTX and DOX in MG63 cells