Related Information

Treacher-Collins syndrome

Treacher-Collins syndrome is a condition that is passed down through families (hereditary) that leads to problems with the structure of the face.

Alternative Names:

Mandibulofacial dysostosis; Treacher Collins-Franceschetti syndrome

Causes:

Changes to one of three genes, TCOF1, POLR1C, or POLR1D, can lead to Treacher-Collins syndrome. The condition can be passed down through families (inherited), but most of the time there is not another affected family member.

This condition may vary in severity from generation to generation and from person to person.

Genetic tests can help identify gene changes linked to this condition.

Treatment:

Hearing loss is treated to ensure better performance in school.

Being followed by a plastic surgeon is very important, because children with this condition may need a series of operations to correct birth defects. Plastic surgery can correct the receding chin and other changes in face structure.