Applications

Metabolic measurement plays a critical role in aging research as the community seeks to understand the healthspan and lifespan trade-offs of the aging process. Recent integrated research from model animals to humans has applied indirect calorimetry to further understand the relationship of cardiovascular disease, insulin resistance, metabolic syndrome and diabetes to senescence. From such a research platform we can better consider which interventions can effectively mitigate age related disease.

Salient Features

Precise calorimetry, food and water intake measurements

High temporal resolution for circadian studies

Instrumentation scales from Drosophila to human

High-throughput and workflow efficiency

GLP compliant solutions, animal safety focus

Activity monitoring with Ethogram capability

Sable Solutions

Depending on the method used, Sable Drosophila metabolic screening systems are capable of measuring the metabolic rates of small groups of Drosophila, or even of individual Drosophila in real time. This unique ... (more)

The Sable MAVEn™ system is an integrated, compact 16-channel flow generator for small insect flow-through respirometry. Each flow is pushed through a sealed container holding a subject animal. The system automatically selects ... (more)

The Promethion Core Behavior Phenotyping System features the modular flexibility to support real-time behavioral studies in a home-cage setting. Capture a complete data-rich archive of behaviors with unbeatable temporal resolution. Second-by-second observations ... (more)

The Promethion Core High Definition Multiplexed Respirometry System for mice synchronously measures energy expenditure, RQ, VO2, VCO2 and activity. The SableHD™ High Definition platform updates once per second for all sensors in ... (more)

The Promethion line features the modular flexibility to support real-time behavioral studies in a home-cage setting with a small sample size or large-scale neurophysiological, pharmacokinetic and toxicological studies. Our high-definition behavioral phenotyping ... (more)

When high temporal resolution is critical, so is the selection of a “continuous” system for indirect calorimetry measurements. Similar to the Promethion multiplexed systems, this high-definition continuous system for mice combines ultra-high ... (more)

When high temporal resolution is critical, so is the selection of a “continuous” system for indirect calorimetry measurements. Similar to the Promethion multiplexed systems, this high-definition continuous system for rats combines ultra-high ... (more)

The Promethion High-Definition Room Calorimetry System is capable of synchronously recording all measured parameters in a completely traceable manner. Key components of this system include the GA-3m2 triple gas O2, CO2, and ... (more)

Contact Us

Our systems are highly customizable for a broad range of applications. Let us help configure a system to meet your specific research needs.

Sable Enables

Before configuring any system, we strive to understand your
application. Our innovative instruments and analysis
tools are then configured and customized
for your application, providing you sound results and efficient workflow.

UPCOMING COURSES

This respirometry course – held in Las Vegas, NV – teaches participants how to measure metabolic rates using indirect calorimetry. We will apply techniques for measuring real-time O2 consumption, CO2 production and water vapor loss for subjects ranging from small invertebrates to large mammals. Participants can work with single animal and high through-put systems in both open-flow[...]

This respirometry course – held in Las Vegas, NV – teaches participants how to use indirect calorimetry in metabolic screening. We will apply techniques for measuring real-time O2 consumption, CO2 production and water vapor loss for laboratory rodents. Measurement systems also include food & water intake, body mass monitoring, wheel running and voluntary activity. Data[...]