The Roles of FOXM1 in Pancreatic Stem Cells and Carcinogenesis
The authors describe the current knowledge about the signaling pathways related to pancreatic cancer stem cells (PCSCs) and the early stages of pancreatic ductal adenocarcinoma development, highlighting the pivotal roles of Forkhead box protein M1 (FOXM1) in PCSCs and their impacts on the development and progression of pancreatic intraepithelial neoplasia. [Mol Cancer]Full Article

Immunology of Cancer Stem Cells in Solid Tumors. A Review
This review summarizes findings on the immunological profile of cancer stem cells (CSCs)/tumor-initiating cells (TICs) as compared with neoplastic non-stem cells and discusses the possible antigens recognized by the patients’ immune system, the in vitro and the potential in vivo immunogenicity of such antigens and the ability of human CSCs/TICs to down-regulate the immune response by the release of a variety of suppressive factors. [Eur J Cancer]Abstract

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Stem Cell Therapeutics Completes $33 Million Private Placement
Stem Cell Therapeutics Corp. announced that it has raised gross proceeds of $33 million through a private placement of units. The financing proceeds will be used to advance the Company’s CD47 cancer stem cell program through IND-enabling studies, manufacturing and Phase I clinical trials. [Stem Cell Therapeutics, Inc.]Press Release