Background: Total gastrectomy is recommended by some groups for poorly differentiated gastric cancer due to the multicentric nature of this tumor. Aim: To assess if subtotal gastrectomy achieves a good disease control in patients with undifferentiated or poorly differentiated gastric cancer. Material and Methods: Retrospective review of medical records of patients with undifferentiated or poorly differentiated gastric cancer, subjected to a subtotal gastrectomy between 1988 and 2006. Five years survival was calculated. Results: Fifty two patients aged 23 to 80 years were identified (30 males). Three had undifferentiated and 49 poorly differentiated tumors. One patient had a positive proximal margin. After a median follow up of 52 months, five years survival was 47%. Thirteen percent were lost from follow up. Conclusions: Five years survival of patients with undifferentiated or poorly differentiated gastric cancer and subjected to subtotal gastrectomy, was 47%.