The billionaire talk show host tweeted about her heartbreak about seeing “babies torn from their parents” at the border. Winfrey’s best friend, Gayle King of CBS This Morning, will be covering the immigration detention center in Texas this week.

Babies torn from their parents.Can’t stand it! Will be watching@GayleKing and her colleaques LiVE from Texas. @CBSThisMorning 7am

“Hope Oprah runs so she can be exposed and defeated just like all of the others!” he tweeted in February.

Ultimately, most commenters just want Winfrey to take action — whether it means running for president or simply using her power for good.

Oprah, you're one of the few people in this country with the power to mobilize & demand answers. Don't WATCH Gayle. Get out, get on the phone, get your famous friends together to DO SOMETHING. We can't watch this happen, we must ACT. You have power – please use it!