Programs to find the sample size or power of studies using the
Sequential Parallel Comparison Design (SPCD) and programs to analyze
such studies. This is a clinical trial design where
patients initially on placebo who did not respond are re-randomized between
placebo and active drug in a second phase and the results of the two phases are
pooled. The method of analyzing binary data with this design is described in
Fava,Evins, Dorer and Schoenfeld(2003) <doi:10.1159/000069738>, and the
method of analyzing continuous data is described in Chen, Yang,
Hung and Wang (2011) <doi:10.1016/j.cct.2011.04.006>.