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Sistemic Limited, the Glasgow and Boston-based leader in the field of micro RNA (miRNA) analysis, today announced an agreement with NHS Scotland, supported by Health Sciences Scotland to work together to in the area of Stratified Medicine to develop novel diagnostic biomarkers for the early detection of diabetic retinopathy and infective keratitis patients.

Leading industry players, Sistemic and Roslin Cells, are going to work together with Scottish Development International (SDI) to make the process of undertaking clinical trials in cell therapy easier, faster and more successful in reaching commercial realisation.

Recent News

Glasgow, SCOTLAND. Sistemic Ltd. is excited to announce significant progress with the development of a miRNA-based assay for assessment of pluripotent stem cell (PSC) contamination in derived cell therapy products. The development is being undertaken in conjunction with LGC, the UK National Measurement Laboratory and Designated Institute for chemical and bio-measurement.

Sistemic Ltd. announced today the publication of its ground-breaking research, undertaken together with TiGenix, identifying a set of circulating miRNA biomarkers which could potentially be used, if further clinically validated, to stratify refractory rheumatoid arthritis patients, prior to treatment, into responders and non-responders to an allogenic cell-based therapy:

Our Products

Sistemic’s platform technology pioneering the approach and development of miRNA-based profiling tools to guide and support Cell Therapy (CT) product development and drug discovery and repositioning

Allows for robust miRNA profiling, customised multi-layered statistical analysis, and biological interpretation and identification of the key markers (KmiR’s™) of cell phenotype. Whilst also seeking to maximise the utility and value of the KmiR’s™ identified

Sistemic's methodologies can also be applied to define, qualify and validating miRNA biomarkers from biofluids and surgical samples for prediction, diagnostic, prognostic, monitoring, toxicity and end-point.

Sistemic’s highly curated knowledge from internal and external projects covering miRNA and cell therapy-based knowledge. The database includes kmiR™ lists from all analyses and high impact meta-data. The knowledgebase is fully integrated with SistemSeek™ literature database