Summariesfor HRH3 gene

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons.

Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine

receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein

and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in

smooth muscles and innervates the blood vessels and the heart in cardiovascular system. (provided by RefSeq, Jul

2008)

GeneCards Summary for HRH3 Gene:

HRH3 (histamine receptor H3) is a protein-coding gene. Diseases associated with HRH3 include hepatic coma, and sleep disorder. GO annotations related to this gene include histamine receptor activity. An important paralog of this gene is HTR2A.