The placebo-controlled study aimed to evaluate the safety and
efficacy of Cutaneous Lysate in the treatment of provoked
vestibulodynia; a form of a vulvar pain symptom called vulvodynia.
Provoked vestibulodynia (formally known as vulvar vestibulitis) is
characterized as a local, sharp pain occurring in response to touch
or pressure to the vulva.

The study included 30 females with provoked vestibulodynia. The
subjects applied either a cream with Cutaneous Lysate or its
placebo twice daily to the vulva over a three-month period with a
one-week wash-out phase, followed by another three months period
with the cross-over product.

The study indicated that the Cutaneous Lysate was effective in
helping to reduce pain during intercourse in females suffering from
provoked vestibulodynia. In the first 12 weeks of use, those using
Cutaneous Lysate showed a significant reduction of pain during
sexual activity whereas those using the placebo did not. The study
also provided some evidence that the females who acquired
vestibulodynia seem more responsive to the treatment.

Although a cure for provoked vulvodynia has not been found as of
yet, Cutaneous Lysate is a promising new treatment for women
suffering from vulvar pain.

About Neogyn®:
Neogyn® Vulvar Soothing Cream is a cosmetic product to help
soothe and comfort the vulva. Formulated with Cutaneous Lysate, a
naturally balanced blend of proteins discovered in Switzerland, the
cream is non-greasy, fast absorbing and free of color additives,
fragrances and analgesics. Recommended by physicians and women's
health professionals, Neogyn® has a unique, patented blend of
naturally balanced proteins that help restore well-being and
comfort with twice daily use over a period of at least 6 to 8
weeks.