An impairment loss against intangible assets of euro 69 million (including euro 37 million in the second quarter related to several products). This item has no cash impact on the Group.

A charge of euro 66 million reflecting an increase in the fair value of contingent considerations related to TargeGen business combination (euro 47 million), and Genzyme including the impact of Bayer contingent consideration (euro 14 million) and the CVR (euro 5 million).

A charge of euro 264 million arising from the workdown of inventories of acquired companies remeasured at fair value due to the application of purchase accounting to acquisitions, of which euro 262 million in the second quarter (due to Genzyme). This item has no cash impact on the Group.

euro 467 million of restructuring costs (including euro 345 million in the second quarter related to continuing transformation of R&D, Industrial Affairs and Operations in Europe).

A non-recurring amortization charge of euro 517 million booked in Q1 2011 due to the change of plan for Merial assets that were previously classified as held for sale or exchange in accordance with IFRS5: this charge corresponds to the depreciation and amortization of Merial assets that would have been recognized for the period from September 18, 2009 to December 31, 2010, had these assets not been classified as held for sale or exchange. This item has no cash impact on the G'/>"/>

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