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Key words: docking, homology modeling, leprosy, M.leprae, molecular, molecular dynamics, ramachandran plot. Therefore identification of the novel drug target and potent drug can be helpful in better prevention of the disease. Alter et.al, (2008) Leprosy as a genetic model for susceptibility to common infectious disease, Hum Genet 2. (1999)Health Policy and Planning; 14(2): 89-102, Oxford University Press. Finite element analysis is a method to computationally model reality in a mathematical form to better understand a highly complex problem. it is a method of determine the most efficient, low cost & reliable operation of a power system by dispatching the available electricity generation resources to supply the load on the system. Abstract: Analysis of the robot hand was analyzed using dedicated software for FEM analysis. in ANSYS, the geometry was updated and the structure meshed using 3D elements. Economic Load Dispatch(ELD) is one of important tasks which provide an economic condition for a power system. Abstract: Leprosy or Hansen's disease is caused by an obligate intracellular pathogen i.e. Leprosy is a granulomatous disease of peripheral nerves and mucosa of the upper respiratory tract. Bowers KJ, Chow E, Xu H, Dror RO, Eastwood MP, Gregersen BA, Klepeis JL, Kolossvary I, Moraes MA, Sacerdoti FD, Salmon JK, Shan Y, Shaw DE (2006) Scalable Algorithms for Molecular Dynamics Simulations on Commodity Clusters. Abstract: For dynamic optimization problems, the aim of an effective optimization algorithm is both to find the optimal solutions and to track the optima over time. Ki "Economic Load Dispatch: A New Hybrid Particle Swarm Optimization Approach"sept.11 2007. Results show that the hydraulic resistance is significantly reduced in the proposed four ports actuators; and the proposed cylinders run faster than the conventional cylinders and a considerable amount of energyis saved as well.

The proposed system is a four ports hydraulic cylinder fitted with a novel flow control valve. Goldenberg, "Design of a new high performance electrohydraulic actuator," in Proceedings of The International Conference on Advanced Intelligent Mechatronics, IEEE/ASME,, 1999, pp. This causes a lot of heat generation and energy loss within the actuators. The study investigates and analyzes the possibilities of reducing the hydraulic resistance and increasing efficiency of the hydraulic actuator. The bacteria have developed resistance against many of the drugs available in the market. Halgamuge "Self-Organizing Hierarchical Particle Swarm Optimizer With Time Varying Acceleration Coefficients" IEEE Trans. A well organized research comprising of analogue based drug design and molecular dynamics plays a major role in obtaining the lead molecules. Black PN, Di Russo CC, Metzger AK, Heimert TL (1992): Cloning, sequencing, and expression of the fad D gene of Escherichia coli encoding Acyl coenzyme A Synthetase.

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