Converting Stem Cell Biology into Stem Cell Medicine

The central goal of our research is make discoveries with the potential of altering the treatment of afflictions for which there are currently no satisfactory therapies. This is the most exciting – and demanding – challenge in all of biomedical research. The difficulties in making such discoveries has all the features that make science exciting, including the opportunity to venture into new territories and make entirely new discoveries, to work on complex problems that are constantly stimulating and to contribute to making the world a better place for individuals and families for whom current medical knowledge is not sufficient to provide benefit.

We pursue these efforts by studying both normal and pathological cell and tissue function to discover new biological principles, and by discovering means of restoring normal function in pathological situations. In addition, we also utilize our new potential therapies as powerful tools of discovery as well as studying their potential as treatments. Thus, we do not approach the challenge of translational research as a one-way flow from the laboratory to the clinic. Instead, we pursue a continuous process of discovery in which information gained from every point along this path has the ability to provide still more new discoveries.