Available hosts

Available applications

Background of Beta-ARK-2 / ADRBK2 antibody

ADRBK2 specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors.The beta-adrenergic receptor kise specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kise 2 has 85% amino acid similarity with beta adrenergic receptor kise 1, with the protein kise catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kises which may serve broadly to regulate receptor function. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and ESTs. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-68 BC036797.1 1-68 69-124 BX387339.2 114-169 125-1307 BC036797.1 69-1251 1308-2783 BC036797.1 1402-2877 2784-7732 AL022329.9 173762-178710 7733-9068 BC063545.1 1-1336

The anti-GRK3 Pab is used in Western blot to detect GRK3 in SK-OV-3 cell lysate (Lane 1) and mouse heart tissue lysate (Lane 2).

Formalin-fixed and paraffin-embedded human brain tissue reacted with ADRBK2 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (ADRBK2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using (ADRBK2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)