Medical Xpress news tagged with:statistical geneticshttp://medicalxpress.com/
en-usMedical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine.Cancerous tumors may spread by pure chanceThe spreading of a cancerous tumor from one part of the body to another may occur through pure chance instead of key genetic mutations, a new study has shown.http://medicalxpress.com/news/2014-07-cancerous-tumors-pure-chance.html
CancerTue, 22 Jul 2014 07:20:01 EDTnews325230371Twins studies to identify the molecular cause of ageingWhat makes us age biologically? We have always been intrigued by this question. Yet, it remains a fundamental research challenge. Now, the EU-funded project, EurHEALTHAgeing, aims to draw together studies of early development with those on longevity and ageing. By doing so, it hopes to decipher the molecular workings that lie behind how we age. But also explain why we get age-related diseases. Scientific coordinator Ana Valdes, a senior lecturer in statistical genetics at King's College London and associate professor at the faculty of medicine and health sciences at the University of Nottingham, in the UK, talks to youris.com about the role of nature versus nurture in ageing. She also talks about the importance of twin studies, epigenetics and how technology is helping us understanding ageing.http://medicalxpress.com/news/2014-06-twins-molecular-ageing.html
GeneticsThu, 26 Jun 2014 08:00:01 EDTnews322986142New tool enhances the search for genetic mutationsConcealed within the vastness of the human genome, (comprised of some 3 billion base pairs), mutations are commonplace. While the majority of these appear to have neutral effect on human health, many others are associated with diseases and disease susceptibility.http://medicalxpress.com/news/2013-08-tool-genetic-mutations.html
GeneticsSun, 25 Aug 2013 13:00:21 EDTnews296635645Gene combinations and interactions affect risk of Crohn's diseaseA statistical model accounting for dozens of different genes in combination—and the interactions between them—is an important step forward in understanding the genetic factors affecting the risk of Crohn's disease (CD), reports a study in Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America (CCFA).http://medicalxpress.com/news/2013-08-gene-combinations-interactions-affect-crohn.html
GeneticsFri, 23 Aug 2013 10:56:00 EDTnews296474146Mathematical models target disease with drugs chosen by your DNAMedicines that are personally tailored to your DNA are becoming a reality, thanks to the work of U.S. and Chinese scientists who developed statistical models to predict which drug is best for a specific individual with a specific disease.http://medicalxpress.com/news/2013-07-mathematical-disease-drugs-chosen-dna.html
MedicationsTue, 16 Jul 2013 10:41:57 EDTnews293190108Israel makes dramatic advance in blindness preventionAccording to the World Health Organization, 80% of blindness is preventable or treatable—but it remains a severe health concern across the globe, even in industrialized countries.http://medicalxpress.com/news/2013-07-israel-advance.html
OphthalmologyWed, 10 Jul 2013 13:46:37 EDTnews292682783Researchers create method to rapidly identify specific strains of illnessResearchers from Boston University School of Medicine (BUSM) and George Washington University (GWU) have developed a method to rapidly identify pathogenic species and strains causing illnesses, such as pneumonia, that could help lead to earlier detection of disease outbreaks and pinpoint effective treatments more quickly. The findings are featured online in the journal Genome Research.http://medicalxpress.com/news/2013-07-method-rapidly-specific-strains-illness.html
GeneticsWed, 10 Jul 2013 13:15:46 EDTnews292680929First prospective trial shows molecular profiling timely for tailoring therapyA clinical trial has shown that patients, and their physicians, are eager to jump into next-era cancer care—analysis of an individual's tumor to find and target genetic mutations that drive the cancer. Results of the study, CUSTOM, are being presented at the 2013 annual meeting of the American Society of Clinical Oncology years before investigators thought they would be ready.http://medicalxpress.com/news/2013-05-prospective-trial-molecular-profiling-tailoring.html
CancerWed, 15 May 2013 18:00:02 EDTnews287856906With two new methods, scientists hope to improve genome-wide association studiesAs scientists probe and parse the genetic bases of what makes a human a human (or one human different from another), and vigorously push for greater use of whole genome sequencing, they find themselves increasingly threatened by the unthinkable: Too much data to make full sense of.http://medicalxpress.com/news/2013-04-methods-scientists-genome-wide-association.html
GeneticsFri, 26 Apr 2013 09:06:17 EDTnews286185970Misregulated genes may have big autism roleA new study finds that two genes individually associated with rare autism-related disorders are also jointly linked to more general forms of autism. The finding suggests a new genetic pathway to investigate in general autism research.http://medicalxpress.com/news/2013-03-misregulated-genes-big-autism-role.html
GeneticsThu, 21 Mar 2013 09:35:36 EDTnews283077329More links found between schizophrenia, cardiovascular diseaseA new study, to be published in the Feb. 7, 2013 issue of the American Journal of Human Genetics, expands and deepens the biological and genetic links between cardiovascular disease and schizophrenia. Cardiovascular disease (CVD) is the leading cause of premature death among schizophrenia patients, who die from heart and blood vessel disorders at a rate double that of persons without the mental disorder.http://medicalxpress.com/news/2013-01-links-schizophrenia-cardiovascular-disease.html
GeneticsThu, 31 Jan 2013 12:00:09 EDTnews278854042Scientists find gene interactions that make cocaine abuse death eight times more likelyScientists have identified genetic circumstances under which common mutations on two genes interact in the presence of cocaine to produce a nearly eight-fold increased risk of death as a result of abusing the drug.http://medicalxpress.com/news/2013-01-scientists-gene-interactions-cocaine-abuse.html
GeneticsTue, 22 Jan 2013 12:56:15 EDTnews278081734New findings in the search for genetic clues to insulin productionIn research published online Dec. 23, 2012 in the journal Nature Genetics, scientists have found three new and relatively rare genetic variants that influence insulin production, offering new clues about the genetic factors behind diabetes..http://medicalxpress.com/news/2012-12-genetic-clues-insulin-production.html
GeneticsSun, 23 Dec 2012 13:00:22 EDTnews275489019Psychology professor seeks clues to psychiatric disorders in DNAData, data everywhere. In genomics research, there is a data deluge, so innovative ways to analyze all that information will play a critical role in future breakthroughs.http://medicalxpress.com/news/2012-12-psychology-professor-clues-psychiatric-disorders.html
Psychology & PsychiatryWed, 12 Dec 2012 08:29:22 EDTnews274523356Harmful protein-coding mutations in people arose largely in the past 5,000 to 10,000 years (Update)(Medical Xpress)—A study dating the age of more than 1 million single-letter variations in the human DNA code reveals that most of these mutations are of recent origin, evolutionarily speaking. These kinds of mutations change one nucleotide – an A, C, T or G – in the DNA sequence. Over 86 percent of the harmful protein-coding mutations of this type arose in humans just during the past 5,000 to 10,000 years.http://medicalxpress.com/news/2012-11-genetic-variation-varies-populations.html
GeneticsWed, 28 Nov 2012 13:00:37 EDTnews273327980Novel type 2 diabetes genetic study involves five major ancestry groupsA consortium of scientists who are taking a novel approach in their research to detect the genetic variations that predispose individuals to type 2 diabetes provided an update of their findings at the American Society of Human Genetics (ASHG) 2012 meeting.http://medicalxpress.com/news/2012-11-diabetes-genetic-involves-major-ancestry.html
GeneticsThu, 08 Nov 2012 19:30:02 EDTnews271614096Surprising findings from Exome Sequencing Project reportedA multi-institutional team of researchers has sequenced the DNA of 6,700 exomes, the portion of the genome that contains protein-coding genes, as part of the National Heart, Lung and Blood Institute (NHLBI)-funded Exome Sequencing Project, one of the largest medical sequencing studies ever undertaken.http://medicalxpress.com/news/2012-11-exome-sequencing.html
GeneticsTue, 06 Nov 2012 08:27:56 EDTnews271412782Sweetened soft drinks linked to preterm birthSweetened (sugar-sweetened and artificially-sweetened) drinks may be linked to preterm birth, according to a recent joint study between Norwegian and Swedish researchers. It is important to prevent preterm birth since it may lead to early death, diseases in infancy and childhood as well as long-term disability.http://medicalxpress.com/news/2012-08-sweetened-soft-linked-preterm-birth.html
HealthThu, 30 Aug 2012 13:35:43 EDTnews265552477Obese kids as bright as thinner peersObesity is not to blame for poor educational performance, according to early findings from research funded by the Economic and Social Research Council (ESRC). In a study that combines statistical methods with genetic information, researchers dispel the false idea that being overweight has damaging educational consequences.http://medicalxpress.com/news/2012-07-obese-kids-bright-thinner-peers.html
Overweight and ObesityFri, 13 Jul 2012 04:10:21 EDTnews261371412A new application allows online statistical analysis of gene-expression dataThe journal Computers in Biology and Medicine has published an article on the new IT application BootstRatio, created by IDIBELL researchers. The application allows online statistical analysis of data from gene expression. It is accessible through http://regstattools.net/br and any scientist is already to use it.http://medicalxpress.com/news/2012-04-application-online-statistical-analysis-gene-expression.html
GeneticsTue, 03 Apr 2012 10:17:43 EDTnews252667053A hidden architecture: Researchers use novel methods to uncover gene mutations for common diseasesHuman geneticists have long debated whether the genetic risk of the most common medical conditions derive from many rare mutations, each conferring a high degree of risk in different people, or common differences throughout the genome that modestly influence risk.http://medicalxpress.com/news/2012-03-hidden-architecture-methods-uncover-gene.html
GeneticsSun, 25 Mar 2012 13:58:06 EDTnews251902663Cleveland Clinic Children's Hospital launches study to genetically test for autismCleveland Clinic Children's Hospital has launched a study to determine whether genetic markers can be used to help identify children who are at risk of developing autism.http://medicalxpress.com/news/2012-02-cleveland-clinic-children-hospital-genetically.html
Autism spectrum disordersWed, 29 Feb 2012 10:17:43 EDTnews249733055The dark path to antisocial personality disorderWith no lab tests to guide the clinician, psychiatric diagnostics is challenging and controversial. Antisocial personality disorder is defined as "a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood," according to the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) of the American Psychiatric Association.http://medicalxpress.com/news/2012-02-dark-path-antisocial-personality-disorder.html
Psychology & PsychiatryTue, 07 Feb 2012 10:07:25 EDTnews247831621Researchers identify genetic signatures of exceptional longevity in re-published studyWhile environment and family history are factors in healthy aging, genetic variants play a critical and complex role in conferring exceptional longevity, according to researchers from the Boston University Schools of Public Health and Medicine, Boston Medical Center, IRCCS Multimedica in Milan, Italy, and Yale University.http://medicalxpress.com/news/2012-01-genetic-signatures-exceptional-longevity-re-published.html
GeneticsWed, 18 Jan 2012 17:24:46 EDTnews246129879We are what we experience: studythe ups and downs, and everything in between -- shape us, stay with us and influence our emotional set point as adults, according to a new study led by Virginia Commonwealth University researchers.http://medicalxpress.com/news/2011-10-we-are-what-experience-study.html
Psychology & PsychiatryWed, 05 Oct 2011 16:14:15 EDTnews237050047