CBG Faculty

Dr. An is a Professor of Biochemistry and Molecular Medicine at the Keck School of Medicine of USC. His research program is focused on using multi-disciplinary biochemical and cellular approaches to understand fundamental concepts and mechanisms of action of epigenetic histone remodeling in human cells. Specifically, his laboratory employs multiple assay systems and methods to dissect molecular details of how histone modification, histone variant exchange, and histone tail proteolysis alter chromatin structure and control gene expression at the level of transcription. Current projects involve genome-wide location analysis and functional characterization of histone marks and downstream effectors that are crucial for epigenetic regulation of cell growth, differentiation, and transformation. Dr. An received his Ph.D. in Biochemistry and Biophysics in 1998 from the Oregon State University and did his postdoctoral training at the Rockefeller University. He began his career on the faculty at USC in 2004.