Turkey is emerging as the center of growing regional opposition to Israel at a critical time. Turkey's leadership and increasing influence, wielded on pliable new governments that have sprung up in the wake of Arab uprisings, could deepen Israel's isolation and pose serious security threats to the Jewish state.

His regional tour comes as Israel's ties with both Turkey and Egypt have reached lows not seen in decades. Turkey, a major trade partner, recently cut ties after a diplomatic row over the 2010 Gaza flotilla, in which eight Turks and one Turkish-American were killed when Israeli commandos raided a boat seeking to break Israel's blockade of the Hamas-run territory.

For starters, Turkey has become like the old Egypt under Nasser – positioning itself as the regional center of opposition to Israel. Meanwhile, Egypt is becoming like the old Turkey. The outcome of the forthcoming Egyptian elections is far from certain. Yet it is very likely that the Muslim Brotherhood will emerge as a power to be reckoned with in the Egyptian polls this fall. Even if the Egyptian military stands for maintaining ties with Israel, the Muslim Brotherhood will push for limiting those ties. Accordingly, Egyptian-Israeli ties will continue to become more cold and tenuous with each passing day.

For the first time, the two major states of the Eastern Mediterranean are aligning against Israel. This is the most important shift in Levantine politics since Camp David or even since 1949 when Turkey recognized Israel. This new balance is a serious threat for Israel, which must now consider an increasingly hostile Turkey and an ever colder and unfriendly Egypt when it evaluates its security environment.

"It is a cause for war, but we decided to act in line with Turkey's grandeur and showed patience," said Erdogan, who had been hoping to visit Gaza on his current tour although those plans appeared to be in question.

Combined with the Palestinians' plan to make a bid for statehood recognition at the United Nations later this month, Erdogan's tour, Turkey's severing of trade ties with Israel, and the Egyptian protesters' attack on the Israeli embassy constitute an enormous diplomatic offensive against the Jewish state, according to the Guardian.

Rattled by diplomatic crises on three fronts, Israel fears it is becoming increasingly isolated in the region. The sense of embattlement is heightened by the Palestinians' bid to have their state recognised at the United Nations in the coming weeks, a move supported by a majority of states.

The defence minister, Ehud Barak, said that Israel must face up to its growing isolation. "There is a wide picture forming around us that includes what happened with Turkey, what is happening with Egypt, and what is happening with the Palestinians," Barak told cabinet colleagues. "These events are not in our control but we can certainly affect the way we face them."