trichostatin A

Treatment with the HDAC inhibitor trichostatin A delayed disease onset and increased survival time in SOD1 research mice

Posted on Thursday, July 28, 2011 - 13:47, By: Amy Madsen

An experimental compound called trichostatin A (TSA) has been shown to improve nerve-cell survival, increase strength and muscle weight, and result in longer life span in mice with a disease resembling ALS (amyotrophic lateral sclerosis, or Lou Gehrig's disease).