On the Wednesday edition of The Action Network NFL Podcast, we talked about Hopkins as strong play in both cash games and guaranteed prize pools, and it’s easy to see why: Hopkins is first in the league with his 0.32 market share of targets and 0.45 share of air yards.

There is, however, some cause for concern based on his splits over the past two seasons. As important as quarterback Deshaun Watson is to the Texans, for Hopkins’ personal production it’s possible that wide receiver Will Fuller is even more important.

With Fuller lined up across from Hopkins, opposing defenses have to respect the speedster’s field-stretching ability, which means that they can’t shade safeties to Hopkins’ side of the field.

The samples are all small, but the numbers suggest that he’s benefited more from Fuller than from Watson, and that might actually make sense. Regardless of whoever throws him the ball, Hopkins gets a lot of targets. But with Fuller on the field, the quality of Hopkins’ targets — and what he can do with those targets — improves dramatically.

T.Y. Hilton: Indianapolis Colts (+1.5) at Houston Texans, 48 O/U

Hilton (ankle) missed practice every day this week and is officially questionable, but wild horses (or colts) couldn’t keep him from suiting up for this game. Hilton has practiced only once since Week 14, but he hasn’t missed a game since returning from hamstring and chest injuries in Week 7.

Even with his balky ankle, Hilton is probably the slate’s second-most desirable receiver.

For his career, Hilton has notable home/away and favorite/underdog splits.

Home (56 games): 5.0 receptions, 80.1 yards, 0.41 touchdowns

Away (52 games): 4.4 receptions, 69.5 yards, 0.32 touchdowns

Favorite (61 games): 5.3 receptions, 85.4 yards, 0.46 touchdowns

Underdog (47 games): 3.9 receptions, 61.4 yards, 0.26 touchdowns

Given that he’s a road dog, this seems like a horrible spot for him, especially since the Texans are tied for fourth with a 90.2 Pro Football Focus (PFF) coverage grade.

The samples are small — they’re always small in football — but come on! Hilton smashes against the Texans, and when playing them he’s great with Luck, as a dog and/or on the road.

In his two games against the Texans earlier in the season, Hilton was true to form.

Week 4 (vs. Texans): 13.5 FanDuel points, 4-115-0 on six targets

Week 14 (at Texans): 24.4 FanDuel points, 9-199-0 on 12 targets

Jam. Him. In.

While in the past a healthy percentage of Hilton’s routes have been of the slot variety:

2017: 36.8%

2016: 57.4%

2015: 27.9%

2014: 40:2%

2013: 44.0%

2012: 42.7%

This season he’s run a career-low 28.0% of his routes out of the slot, so he won’t spend too much time facing slot corner Kareem Jackson, who leads the secondary with his 85.7 PFF grade.

Instead, the corner Hilton is likely to face most is Shareece Wright, who has a 60.8 PFF grade. In Weeks 4 & 14, he allowed two touchdowns to the Colts, who singled him out with 18 targets in his coverage.