Patrick Dempsey plays Dylan in TRANSFORMERS: DARK OF THE MOON, from Paramount Pictures.

PHOTO: Handout, Paramount Pictures

Left to right: Rosie Huntington-Whiteley plays Carly and Patrick Dempsey plays Dylan in Paramount Pictures' TRANSFORMERS: DARK OF THE MOON.

PHOTO: Handout, Paramount Pictures

Patrick Dempsey poses for a photo during the IZOD GQ party celebrating a Century of Speed, Style and Stars at the 100th Anniversary Indianapolis 500 on May 28, 2011 at the Indianapolis Museum of Art in Indianapolis, Indiana.

Patrick Dempsey as Dr. Harrison Copeland and Jennifer Garner as Julia Fitzpatrick in New Line Cinema's romantic comedy "Valentine's Day".

PHOTO: Handout, Warner Bros. Pictures

In Columbia Pictures' Made of Honor, when Tom's (Patrick Dempsey, right) best friend, Hannah (Michelle Monaghan, left), asks him to be her maid of honor, Tom accepts - but only so he can woo the bride-to-be and attempt to stop the wedding before itís too late.

PHOTO: Handout, Columbia Pictures

In Columbia Pictures' Made of Honor, when Tom's (Patrick Dempsey, right) best friend, Hannah (Michelle Monaghan, left), asks him to be her maid of honor, Tom accepts - but only so he can woo the bride-to-be and attempt to stop the wedding before itís too late.

PHOTO: Handout, Columbia Pictures

In Columbia Pictures' Made of Honor, when Tom's (Patrick Dempsey, right) best friend, Hannah (Michelle Monaghan, left), asks him to be her maid of honor, Tom accepts - but only so he can woo the bride-to-be and attempt to stop the wedding before itís too late.

PHOTO: Handout, Columbia Pictures

In Columbia Pictures' Made of Honor, when Tom's (Patrick Dempsey, right) best friend, Hannah (Michelle Monaghan, left), asks him to be her maid of honor, Tom accepts - but only so he can woo the bride-to-be and attempt to stop the wedding before itís too late.

PHOTO: Handout, Columbia Pictures

In Columbia Pictures' Made of Honor, when Tom's (Patrick Dempsey, right) best friend, Hannah (Michelle Monaghan, left), asks him to be her maid of honor, Tom accepts - but only so he can woo the bride-to-be and attempt to stop the wedding before itís too late.

PHOTO: Handout, Columbia Pictures

In Columbia Pictures' Made of Honor, when Tom's (Patrick Dempsey, right) best friend, Hannah (Michelle Monaghan, left), asks him to be her maid of honor, Tom accepts - but only so he can woo the bride-to-be and attempt to stop the wedding before itís too late.

PHOTO: Handout, Columbia Pictures

In Columbia Pictures' Made of Honor, when Tom's (Patrick Dempsey, right) best friend, Hannah (Michelle Monaghan, left), asks him to be her maid of honor, Tom accepts - but only so he can woo the bride-to-be and attempt to stop the wedding before itís too late.

PHOTO: Handout, Columbia Pictures

"Grey's Anatomy" focuses on young people struggling to be doctors and doctors struggling to stay human. It's the drama and intensity of medical training mixed with the funny, sexy, painful lives of interns who are about to discover that neither medicine nor relationships can be defined in black and white. Real life only comes in shades of grey.

PHOTO: Handout/Frank Ockenfels, ABC Television Network

Patrick Dempsey stars as "Dr. Derek Shepherd" on "Grey's Anatomy" on the ABC Television Network.

PHOTO: Handout/Frank Ockenfels, ABC Television Network

Actor Patrick Dempsey appears onstage during MTV's Total Request Live at the MTV Times Square Studios November 19, 2007 in New York City.