In the grim darkness of the 41st millennium, the Space Marines are the supreme defenders of humanity, the Emperor's ultimate shock troops.

The Iron Snakes Chapter has sworn a pledge to protect the Reef Stars from ruin, whatever the cost. Brothers of the Snake follows Sergeant Priad and the Damocles Squad as they battle to preserve humanity against the myriad foes that threaten to destroy it, from the depraved dark eldar to a vast ork Waaagh!