Wilkinson plays off a handicap of three, despite having had his right toe and the joint surrounding it amputated and suffering from Buerger's Disease, an inflammation of the arteries, veins and nerves in the legs which leads to restricted blood flow.

RNL has completed one phase I trial for spinal cord injury, and one Phase II clinical trial for Osteoarthritis, under the KFDA in South Korea and is near to the completion of a clinical trial for Buerger's Disease trial.

Almost all patients with this disease have a history of heavy cigarette smoking, and cessation and resumption of smoking have been documented to produce remission and exacerbation of the discase [65] A case has been reported relating smokeless tobacco use to Buerger's disease as well [66] It appears that some constituent in tobacco, whether smoked or chewed, acts as a cofactor in the development of the disease.

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