Molecular StagingMolecular Staging is addressing this demand with a portfolio of products and services based on technologies that are transforming the detection and measurement of both proteins and nucleic acids.

Conclusion

The specificity of the DNA segments catalyzed by the enzyme DNA ligase can be exploited in systems designed to identify the presence of a target sequence of nucleic acids in a biological sample.

The amplification methods based on the ligase can increase sensitivity without causing a decrease in specificity. Have described modifications of these techniques that reduce non-specific ligation. The automation of testing in the future allow the routine use of such technology in the clinical laboratory.