This project is devoted to develop innovative nanoparticle toolbox, consisting of a new generation self-organized polymer-based materials that could be used for biomedical applications in cancer, tuberculosis and inflammation treatment. The tools consist of biodegradable polymeric nanoparticles; their surface will be covered by a polymer that carries groups targeting specific receptors on theranostic target and groups allowing complexation of the polymer to the nanoparticle. The new systems will be tested for their anti-cancer activity, anti-bacterial and anti-inflammatory activity using in vitro cell cultures and in vivo models of the diseases.

Approved grant

1 322 981 EUR

Project Duration

Start date: 15th July 2014, End date: 30th April 2017

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Author

Department 58 (Section 07)

This department carries out conceptual activities and the entire operational agenda connected with ensuring performance of the Ministry's tasks in respect of the international institutions of which the Czech Republic is a member... more