METHOD FOR HOMOGENIZING BILE ACID DERIVATIVES
The present invention relates to a method for preparing bile acid derivatives with a protected hydroxyl group in position 3, the method comprising the contacting of a bile acid derivative, having an unprotected 3-alpha-hydroxyl group, wi...

KETOREDUCTASES
The invention relates to ketoreductases and the use thereof. The ketoreductases of the invention are particularly useful for enzymatically catalyzing the reduction of ketones to chiral or non-chiral secondary alcohols and oxidation of ch...

WO/2018/234479A2

METHOD FOR HOMOGENIZING BILE ACID DERIVATIVES
The present invention relates to a method for preparing bile acid derivatives with a protected hydroxyl group in position 3, the method comprising the contacting of a bile acid derivative, having an unprotected 3-alpha-hydroxyl group, wi...

WO/2018/227644A1

METHOD FOR CATALYZING STEROIDAL BIOLOGICAL TRANSFORMATION
Provided is a method for catalyzing steroidal biological transformation. In the method, sodium alginate-grafted cyclodextrin immobilized cells are used as a catalyst, so as to implement the cyclic utilization of a cyclodextrin medium, th...

GLYCOSYLTRANSFERASE, MUTANT, AND APPLICATION THEREOF
Provided are a glycosyltransferase, a mutant, and an in vitro glycosylation method. The method comprises the steps of: transferring a glycosyl group of a glycosyl donor to a hydroxyl group at the C-3 position of a tetracyclic triterpenoi...

WO/2018/204483A3

METHODS FOR MAKING HIGH INTENSITY SWEETENERS
Provided herein include methods of making mogroside compounds, e.g., Compound 1, compositions (for example host cells) for making the mogroside compounds, and the mogroside compounds made by the methods disclosed herein, and compositions...

WO/2018/204483A2

METHODS FOR MAKING HIGH INTENSITY SWEETENERS
Provided herein include methods of making mogroside compounds, e.g., Compound 1, compositions (for example host cells) for making the mogroside compounds, and the mogroside compounds made by the methods disclosed herein, and compositions...

WO/2018/133844A1

CYTOCHROME P450 MUTANT PROTEIN AND APPLICATIONS THEREOF
The present invention provides a cytochrome P450 mutant protein and applications thereof. In particular, in the present invention, after the modification of key sites in the cytochrome P450 CYP716A47, the PPD production and the PPD/DM pr...

RECOMBINANT MICROORGANISM FOR PRODUCING STEVIOL GLYCOSIDE
The present invention relates to a recombinant microorganism for producing a steviol glycoside and a method for producing a steviol glycoside. The recombinant microorganism for producing a steviol glycoside according to the present inven...

STEROL PRODUCTION METHOD
Algae that generates a sterol and a sterol production method that uses the algae. According to the present invention, a sterol is produced by culturing algae, such as strain AJ7867 (FERM BP-22304) and strains derived therefrom, that has ...

PRODUCTION OF STEROLS IN MODIFIED YEAST
The present invention is related to production of a sterol mix in a modified yeast cell, wherein the amount of zymosterol present in said mix is dramatically reduced or abolished via modification of sterol acyltransferase activity within...

MUTANT PROTEIN OF GLYCOSYLTRANSFERASE AND USES THEREOF
Provided are a mutant protein of glycosyltransferase and uses thereof. Specifically, by using homology alignment and site-directed mutagenesis, a new mutant protein of glycosyltransferase is discovered. The mutant protein is a non-natura...

21-HYDROXYLATION OF STEROIDS
Generally, the present invention relates to the field of steroid hydroxylation. More specifically, the present invention relates to a method for the 21-hydroxylation of steroids in cells. It also relates to cells expressing a steroid 21-...