This meeting will bring together statisticians, clinicians and other methodologists for discussion of common statistical issues in imaging studies. Challenges will be illustrated by examining a clinical example – centralised reading of endoscopy for clinical trials in Inflammatory Bowel Disease – but they are also widely applicable to other imaging modalities.

Statistical issues for discussion in this meeting will include:

Sample size considerations in imaging studies

Inter-rater agreement and the effect of subjective image assessment

Reproducibility of endpoint assessment

Agreement and variability between repeated imaging time-points

Timetable

12:00 Registration and Lunch

13:00 Introduction and Overview

Tom Fanshawe (Nuffield Department of Primary Care Health Sciences, University of Oxford) & Sue Mallett (School of Health and Population Sciences, University of Birmingham)