McAfee AV and Drive Encryption both are two different products. You can uninstall AV without decrypting Drive Encryption. But if you want to uninstall Drive Encryption too, then you have to decrypt the machine and then uninstall.

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McAfee Agent is one thing and Antivirus is another. As McAfee employees responded, you can uninstall Antivirus (Endpoint Security or VirusScan Enterprise) and the encryption of the drive will not be affected.

But uninstalling the agent would not be desirable, in my opinion, if the system remained encrypted. The agent is the one that connects the system to the ePO where the Drive Encryption users and encryption keys are stored.

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