Bricks and fallen rubble cover a car with the old courthouse in the background following an earthquake Sunday, Aug. 24, 2014, in Napa, Calif. A large earthquake rolled through California's northern Bay Area early Sunday, damaging some buildings, igniting fires, knocking out power to tens of thousands and sending residents running out of their homes in the darkness. (AP Photo/Eric Risberg)

Nina Quidit cleans up the Dollar Plus and Party Supplies Store in American Canyon Calif. after an earthquake on Sunday Aug. 24, 2014. Quidit and her husband were woken up in the early morning hours by the store's alarm company and immediately drove in to begin clean up. The 6.0-magnitude quake caused six significant fires, including at four mobile homes, Napa Division Fire Chief Darren Drake said. (AP Photo/Alex Washburn)

People look at a damaged building with a top corner exposed following an earthquake Sunday, Aug. 24, 2014, in Napa, Calif. A large earthquake rolled through California's northern Bay Area early Sunday, damaging some buildings, igniting fires, knocking out power to tens of thousands and sending residents running out of their homes in the darkness. (AP Photo/Eric Risberg)

People look at a damaged building with a top corner exposed following an earthquake Sunday, Aug. 24, 2014, in Napa, Calif. A large earthquake rolled through California's northern Bay Area early Sunday, damaging some buildings, igniting fires, knocking out power to tens of thousands and sending residents running out of their homes in the darkness. (AP Photo/Eric Risberg)

People look at a damaged building with a top corner exposed following an earthquake Sunday, Aug. 24, 2014, in Napa, Calif. A large earthquake rolled through California's northern Bay Area early Sunday, damaging some buildings, igniting fires, knocking out power to tens of thousands and sending residents running out of their homes in the darkness. (AP Photo/Eric Risberg)

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NAPA — A large earthquake caused significant damage in California’s northern Bay Area early Sunday, sending at least 70 people to a hospital, igniting fires, knocking out power to tens of thousands and sending residents running out of their homes in the darkness.

Vanessa DeGier, spokeswoman for Queen of the Valley hospital in Napa, says the facility has treated more than 70 people, most for cuts, bumps and bruises. She says the facility has treated a hip fracture and heart attack, but it’s unclear if it was related to the 6.0-magnitude earthquake. The hospital has set up a triage tent and many people are still coming in, DeGier said.

Two major injuries have been reported, and hospitals have been very busy with moderate injuries, Napa Division Fire Chief John Callanan said earlier. The quake caused six significant fires, including at four mobile homes, Napa Division Fire Chief Darren Drake said. The damage from the fires is not yet clear but it appears significant, he said. Several other smaller fires have been reported and firefighting efforts have been complicated by broken water mains.

The earthquake struck just before 3:30 a.m. about 4 miles northwest of American Canyon, which is about 6 miles southwest of Napa, in California wine country, Leslie Gordon of the U.S. Geological Survey said. It’s the largest earthquake to shake the Bay Area since the 6.9-magnitude Loma Prieta quake in 1989, the USGS said. That earthquake struck the San Francisco Bay Area on Oct. 17, 1989 during a World Series game between the San Francisco Giants and the Oakland Athletics, collapsing part of the Bay Bridge roadway and killing more than 60 people, most when an Oakland freeway fell.

“There’s collapses, fires,” said Napa Fire Capt. Doug Bridewell, standing in front of large pieces of masonry that broke loose from a turn of the century office building where a fire had just been extinguished. “That’s the worst shaking I’ve ever been in.”

Bridewell, who said he had to climb over fallen furniture in his own home to check on his family before reporting to duty, said he was starting to see more reports of injuries.

The shaking emptied cabinets in homes and store shelves, set off car alarms and had residents of neighboring Sonoma County running out of their houses and talking about damage inside their homes. Officials say widespread power outages have been reported in the area.

“It was a rolling quake, said Oakland resident Rich Lieberman. “It started very much like a rolling sensation and just got progressively worse in terms of length. Not so much in terms of shaking, but it did shake. It felt like a side-to-side kind of rolling sensation. Nothing violent but extremely lengthy and extremely active.”

California Highway Patrol Officer Kevin Bartlett said cracks and damage to pavement closed the westbound Interstate 80 connector to westbound State Route 37 in Vallejo and westbound State Route 37 at the Sonoma off ramp. He says there haven’t been reports of injuries or people stranded in their cars, but there are numerous flat tires from motorists driving over damaged roads.

Highway Patrol and the California Department of Transportation was checking roadways for damage, Bartlett said. California Highway Patrol Officer Daniel Hill said that road damage appears confined to the Napa and Sonoma areas.