Appearance: The origin of the Isis knot is unknown but it may be a variation of the ankh, which it resembles except that its crossing arms curve downward. The tiet was often shown with the ankh and djed signs as early as the Third Dynasty. The hieroglyph is usually translated to mean "life" or "welfare."

Meaning: It may be because it was so often paired with the djed pillar (a symbol of Osiris) that the tiet came to be associated with Isis. The djed and the tiet used together often alluded to the binary nature of life.

The tiet was often called the "knot of Isis" and the "blood of Isis." Complex myths surround these names, but it is uncertain whether they came about to explain the established epithets or if they truly relate the origin of the tiet. As it was called the "blood of Isis", amulets of the sign were often fashioned from red stones such as carnelion and jasper, or from red glass.

In written sources, the meaning and symbolism of the tjet knot seem to be similar to those of the ankh, that is, life, and the sign is thus often translated that way. The tjet shape is used in personal objects, such as a cosmetic spoon, as early as the 1st or 2nd dynasty, and as a decorative symbol as early as the 3rd Dynasty, when it appears with both the ankh and with the djed signs, and later, with the was scepter.

Perhaps because of its association with the djed pillar, which became associated with Osiris, the tjet knot became associated with Isis, and thus it is often called "the knot of Isis" or even "the blood of Isis." Because of the latter term, the sign was cited in a Spell in the Book of Going Forth by Day, in the New Kingdom period, and was used as a funerary amulet, made of a red semi-precious stone such as carnelian or jasper.

From the Old Kingdom times, the knot was also used as a badge of office for the kherep-ah or Manager of the Palace

Thank you very much!!! So, it means it has to be translate the same as the 'nk sign, isn't it?
Do you think it is possible that it might have the same meaning than the 'nk sign but that it has to be used referred to death, and so connected to the resurrection of the dead? I had assumed ( surely not properly) that the fact that it refers to the "blood os Isis" was a reference to the rebuilt of Osiris body.....
What do you think? Thank you again for your help

No No No! The Isis knot should not be translated as meaning 'death' or 'life', because it neither is voiced as 'nk, nor means either of those things.

The Isis knot was used from the Third Dynasty onwards along with Djed, Was and Ankh as one of the key symbols that adorned shrines and tombs (as Mary500 said). Its significance comes from its importance during the tests before reaching the Field of Iaru. The so-called Isis Knot was used as a part of Spell 156 of the Book of the Dead, in which it would symbolically infuse the blood of Isis into the dead one, and "drive off those who would perform criminal acts against the user".

The symbol does not therefore signify life, but is used as a determinative for 'wellbeing' and is used in the word for 'motherly protection' in Egyptian. It is most commonly used in Egyptian in the word 'tit' (no childish giggles) or as a later variant tjet, which means 'tjet protection amulet'. Egyptologists and Classicists guessed that the Isis knot must be voiced as 'tjet' due to this word, and the Isis knot being used as a phonetic complement in it.

When used in conjunction with the Djed pillar of Osiris, the two signs show the timelessness of nature, and how both paternal stability and maternal protection must be used together to defend the earth.

Thank you all! I'm from Turin, north west of Italy, near the borders of France, but I live actually in the neighborhood of Aosta.....of course you can tell her about me (but don't laugh too much! )...
Ciao ciao

uhm...something like....too many montains....??? I'm joking, I love Italy and my town Turin....France is completely different, we don't have that much in common, even if it looks like!
There always have been a strange antagonism between Italians and french people....actually I guess that frenchs are strange to many europeans countries..... ......viva l'Italia!

No, don't misunderstand me! France is lovely, but has nothing to do with Italy, which doesn't mean that one is best than the other, but just that I like best Italy.....uhm....do you get my meaning? or am I too confused???

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