Ibuprofen is an analgesic sold under various names including Advil, Motrin, and Nuprin. The material is sole as a racemic mixture, but only one enantiomer acts as ar analgesic. The other enantiomer is inactive. Assign R oi S forms to the two enantiomers of ibuprofen. [Pg.68]

The aluminum salts of dmgs are significant for two principal reasons reduction of dmg acidity in the stomach lining and reduction of undeskable flavor. Examples are the aluminum salts of glycine, acetylsahcyhc acid, ibuprofen, flurbiprofen, fenoprofen, flufenamic acid, oxaprozin, and a variety of aminobenzoic acid. Some of these compounds are Hsted in Table 2. [Pg.143]

Lipase-catalyzed kinetic resolutions are often practical for the preparation of optically active pharmaceuticals (61). For example, suprofen [40828-46-4] (45), which is a nonsteroidal antiinflamatory dmg, can be resolved by Candida glindracea]i 2Lse in >95% ee at 49% conversion (61). Moreover, hpase-based processes for the resolution of naproxen [22204-53-1] and ibuprofen [15687-27-1] (61) have also been developed. [Pg.338]