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We are a clinical­stage biopharmaceutical company focused on discovering and developing engineered monoclonal antibody therapeutics to treat severe and life­threatening diseases with unmet medical needs. We use our proprietary XmAb® technology platform to create next­generation antibody product candidates designed to treat autoimmune and allergic diseases, cancer and other conditions. In contrast to conventional approaches to antibody design, which focus on the portion of antibodies that interact with target antigens, we focus on the portion of the antibody that interacts with multiple segments of the immune system and controls antibody structure. This portion, referred to as the Fc domain, is constant and interchangeable among antibodies. Our engineered Fc domains, the XmAb technology, can be readily substituted for natural Fc domains.