Lynne Cheney (born August 14, 1941) is the wife of Vice President Richard B. Cheney. They dated in high school and married in 1964. Unofficially, she is the Second Lady of the United States.

Within the George W. Bush administration, Lynne Cheney is regarded as being quite politically involved and is a vocal supporter of Republican party politics and politicians. In this respect she is somewhat of a contrast to First Lady Laura Bush who has largely distanced herself from overt partisanship.