The present study aimed to evaluate the changes in the haemato-biochemical constituents in dystocia affected Marathwadi buffaloes. Total 30 buffaloes were presented to Teaching Veterinary Clinical Complex, Udgir. Buffaloes presented at TVCC were divided into 5 equal groups. The buffalo in group I (n= 6) normally parturated, in group II (n= 6) dystocia due to uterine torsion kept as control, in group III (n= 6) dystocia due to uterine torsion were given vitamin E and Se intramuscularly prior to detorsion kept as torsion treatment. Buffaloes in group IV (n= 6) dystocia due to incomplete cervical dilatation were not given Vitamin E and Se and served as control. And in group V dystocia due to incomplete cervical dilatation (n= 6) were given vitamin E and Se intramuscularly before initiation of treatment. Mean Hb concentration significantly increased 48 hrs after parturition as compared to before parturition in all the groups. Mean PCV concentration significantly increased (P<0.01) 48 hrs after parturition as compared to before parturition in all the five groups. Mean total protein concentration significantly decreased (P<0.05) 48 hrs after parturition as compared to before parturition in all the groups. The mean albumin concentration in Group I, III, IV and V on 48 hrs after parturition decreased significantly (P<0.01) as compared to before parturition.