Research Area:

The microbial communities, their metabolites and components not only influence immune homeostasis, immune-mediated diseases and disorders; they also modulate both the central nervous system and enteric nervous system. Thus, I am interested in gut microbiota, metabolites, host immunity and the related neuron response.

Using a genome-wide CRISPR/Cas9 genetic screening system and transgenic mouse model, we are trying to investigate the cascade of Microbiota-Immune-Neuron response and demonstrate the Gut-Brain interaction.