Nectar a new wine bar at 2235 Fredrick Douglas Blvd.

The latest blow to the local business scene is the closing of Nectar Wine Bar.

Owner Jai Jai Greenfield’s roots are in Harlem, which is why she opened the wine bar four years ago. It was among the first of a wave of new businesses that came to a now emerging corridor of Frederick Douglass Blvd.

But tough economic times have shuttered the area’s first wine bar near W. 121 St., Greenfield said.

“There’s not enough resources for small businesses,” said Greenfield, who will continue to sell wine at her other business Harlem Vintage, located next door.