The team found that dyspepsia, with and without reflux symptoms, accounted for 43% of upper endoscopies.

In addition, among dyspeptic patients, 36.5% were younger than 50 years of age without alarm symptoms.

The researchers found that esophageal or gastric malignancy in patients with dyspepsia was associated with increasing age, male sex, Asian race, Native American race, and symptoms of weight loss and vomiting.

The research group also found that suspected Barrett’s esophagus (>=2cm) was associated with reflux symptoms, male sex, age, and white race.