Green tea compound may help combat rheumatoid arthritis

Washington, Feb 17 (IANS) A compound in green tea may offer a potential new approach to combating the joint pain, inflammation and tissue damage caused by rheumatoid arthritis.

The researchers confirmed their findings in a pre-clinical animal model of human rheumatoid arthritis, where they observed that ankle swelling in animals given the compound in a 10-day treatment plan was markedly reduced.

The discovery was detailed in the journal Arthritis and Rheumatology.

“Existing drugs for rheumatoid arthritis are expensive, immunosuppressive and sometimes unsuitable for long-term use,” said lead researcher Salah-uddin Ahmed from Washington State University in Spokane, US.

So the team evaluated a phytochemical called epigallocatechin-3-gallate (EGCG), which is a molecule with anti-inflammatory properties found in green tea.

The researchers found that EGCG has high potential as a treatment for rheumatoid arthritis because of how effectively the molecule blocks the effects of the disease without blocking other cellular functions.

“This study has opened the field of research into using EGCG for targeting TAK1 – an important signaling protein – through which proinflammatory cytokines transmit their signals to cause inflammation and tissue destruction in rheumatoid arthritis,” Ahmed said.

Rheumatoid arthritis is a debilitating autoimmune disorder that mostly affects the small joints of the hands and feet.

The opinions, views, and thoughts expressed by the readers and those providing comments are theirs alone and do not reflect the opinions of www.mangalorean.com or any employee thereof. www.mangalorean.com is not responsible for the accuracy of any of the information supplied by the readers. Responsibility for the content of comments belongs to the commenter alone.

We request the readers to refrain from posting defamatory, inflammatory comments and not indulge in personal attacks. However, it is obligatory on the part of www.mangalorean.com to provide the IP address and other details of senders of such comments to the concerned authorities upon their request.

Hence we request all our readers to help us to delete comments that do not follow these guidelines by informing us at info@mangalorean.com. Lets work together to keep the comments clean and worthful, thereby make a difference in the community.