The ethical issues concerning the use of PGD (Preimplantation Genetic Diagnosis) to select embryos of a particular HLA (Human Leukocyte Antigen) type are numerous. They arise from the potentially conflicting interests between those of the pre-existing child, the subject of a treatment which may be curative, and those of the sibling to be created, who cannot give consent to the donation, together with the problem of the destruction of potentially healthy embryos. This essay focuses on the web of vulnerabilities affecting (...) the parents, the sick child and the “saviour sibling,” while addressing three areas: science, bioethics and literature. The novel My Sister’s Keeper, by Jodi Picoult, provides the reader with an in-depth view of the conflicting interests and emotional problems that affect the Fitzgeralds, a family experiencing the pain of seeing one of their children dying while facing the tragic consequences of trying to save this child by having another offspring. (shrink)

Pace Benovsky's ‘Presentism and Persistence,’ presentism is compatible with perdurantism, tropes and bundle-of-universals theories of persisting objects. I demonstrate how the resemblance, causation and precedence relations that tie stages together can be accommodated within an ersatzer presentist framework. The presentist account of these relations is then used to delineate a presentist-friendly account of the inter-temporal composition required for making worms out of stages. The defense of presentist trope theory shows how properties with indexes other than t may be said to (...) exist at t. This involves an account of how times other than t exist at t, and how times may be multiply located at any given time. Benovsky's objection to bundles of universals is shown to assume that a bundle of properties must have the properties of its element properties. (shrink)

Provocatively, David Armstrong's properties are supposed to be both universals and spatio-temporal. What does this amount to? I consider four of Armstrong's views, in order of ascending plausibility: (1) the exemplification account, on which universals are exemplified by space-times; (2) the location account, on which universals are located at space-times; (3) the first constituent account, on which spatio-temporal relations are elements of what I call the form of time; and, the true view, (4) the second constituent account, on which universals (...) are spatio-temporal only 'derivatively' by being constituents of states of affairs which are so 'primarily'. The first two accounts are rejected because they entail that space-times must be substantival. In making plausible the second constituent account, I distinguish primitive and derivative spatio-temporality. Something is primitively spatio-temporal when it is at a space-time, or stands in spatio-temporal relations. Something is derivatively spatio-temporal when it is a constituent of something primitively spatio-temporal. (shrink)

A investigação de um domínio amplo da realidade, como a evolução dosseres vivos, pode dar origem a diferentes “teorias”, cada uma consoantecom uma particular perspectiva que se considere. Para que se proceda auma análise detalhada dos pressupostos e conceitos que baseiam umadeterminada visão, o método axiomático parece ser a melhor das opções.Neste artigo, são discutidas algumas teorias da biologia evolutiva de umponto de vista axiomático, mostrando-se de que forma se pode apresentarum “predicado de Suppes” para a teoria sintética da evolução, (...) comodetalhado em outro local . Estaformulação é utilizada, dentre outras coisas, para se discutir a noção deaptidão darwiniana, bem como para explorar as relações entre a teoriadarwiniana da seleção natural e a genética de populações.The investigation of a wide field of knowledge, as evolution of living beings,may originate different “theories”, each one acting as a particularperspective we have about the domain. In order to proceed a philosophicalanalysis of the underlying assumptions of a particular view, it seems thatthe use of the axiomatic method is still the better way. Here, we discuss some theories of evolutionary biology from an axiomatic point of view, bymeans of a Suppes predicate for the synthetic theory of evolution, alreadydetailed in MAGALHÃES and KRAUSE . This formulation is hereused, among other things, to deal with the concept of Darwinian fitness, soas to explore the relationships between Darwinian theory and populationgenetics. (shrink)

The article recasts the problem of globalization from a Marxist standpoint, so as to stress the concrete process of hegemonic economic domination, as opposed to reflections and speculations on universal solutions, with particular emphasis on the Latin American situation. KEY WORDS – Globalization. Latin America. Marxism. Universalism.

We explore the distinctive characteristics of Mexico's society, politics and history that impacted the establishment of genetics in Mexico, as a new disciplinary field that began in the early 20th century and was consolidated and institutionalized in the second half. We identify about three stages in the institutionalization of genetics in Mexico. The first stage can be characterized by Edmundo Taboada, who was the leader of a research program initiated during the Cárdenas government (1934-1940), which was primarily directed towards improving (...) the condition of small Mexican farmers. Taboada is the first Mexican post-graduate investigator in phytotechnology and phytopathology, trained at Cornell University and the University of Minnesota, in 1932 and 1933, respectively. He was the first investigator to teach plant genetics at the National School of Agriculture and wrote the first textbook of general genetics, Genetics Notes, in 1938. Taboada's most important single genetics contribution was the production of "stabilized" corn varieties. The extensive exile of Spanish intellectuals to Mexico, after the end of Spain's Civil War (1936-1939), had a major influence in Mexican science and characterizes the second stage. The three main personalities contributing to Mexican genetics are Federico Bonet de Marco and Bibiano Fernández Osorio Tafall, at the National School of Biological Sciences, and José Luis de la Loma y Oteyza, at the Chapingo Agriculture School. The main contribution of the Spanish exiles to the introduction of genetics in Mexico concerned teaching. They introduced in several universities genetics as a distinctive discipline within the biology curriculum and wrote genetics text books and manuals. The third stage is identified with Alfonso León de Garay, who founded the Genetics and Radiobiology Program in 1960 within the National Commission of Nuclear Energy, which had been founded in 1956. The Genetics and Radiobiology Program rapidly became a disciplinary program, for it embraced research, teaching, and training of academics and technicians. The Mexican Genetics Society, created by de Garay in 1966, and the development of strains and cultures for genetics research were important activities. One of de Garay's key requirements was the compulsory training of the Program's scientists for at least one or two years in the best universities of the United States and Europe. De Garay's role in the development of Mexican genetics was fundamental. His broad vision encompassed the practice of genetics in all its manifestations. (shrink)

G.E. Moore's philosophical legacy is ambiguous. On the one hand, Moore has a special place in the hearts of many contemporary analytic philosophers. He is, after all, one of the fathers of the movement, his broadly commonsensical methodology informing how many contemporary analytic philosophers practise their craft. On the other hand, many contemporary philosophers keep Moore's own substantive positions at arm's distance. According to many epistemologists, one can find no finer example of how to beg the question than Moore's case (...) against the sceptic. And, according to many moral philosophers, one can find no more vivid case of philosophical extravagance than Moore's non-naturalism. Given this ambiguity, one wonders: How should we assess Moore's legacy in epistemology and ethics – the two areas of philosophy in which Moore did most of his work?That is the task of this welcome collection of 16 essays. The list of contributors to the book is impressive: Crispin Wright, Ernest Sosa, Ram Neta, William Lycan, C.A.J. Cody, Paul Snowdon, Michael Huemer and Roy Sorenson consider Moore's work in epistemology. Stephen Darwall, Terry Horgan, Mark Timmons, Richard Fumerton, Charles Pigden, Robert Shaver, Joshua Gert, Jonathan Dancy and the editors of the book explore Moore's views in ethics. As one might expect, given this list of contributors, the quality of the essays is very high. Moreover, there is a decidedly constructive tone to many of them. While not willing to overlook Moore's mistakes, many of the essays endeavour to explore what is valuable in Moore's thought, critically engaging with positions that, not too long …. (shrink)