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Topic review: Hypertension in pregnancy: The current state of the art

PM me your address - we can't share the full-txt until it comes out from under copyright In a year or so!

On that note, most of the links in this forum are to abstracts, but the PubMed screen will have a link to the full text of the paper, usually in the upper right corner, once the article comes out from behind the paywall. (There is a huge argument going on right now about how publicly funded research should be available to the public immediately, and not hidden behind a paywall to benefit a third party (publishers, who provided a much more useful service before the Internet.))

Anyway, it mostly says "we have tested a ton of approaches to prediction and prevention, and none of them really work regardless of what you may have heard in the past, and we really need to find something that works for at least 48 hours to get steroids into play so fewer people are dying, kthx."

PM me your address - we can't share the full-txt until it comes out from under copyright In a year or so!

On that note, most of the links in this forum are to abstracts, but the PubMed screen will have a link to the full text of the paper, usually in the upper right corner, once the article comes out from behind the paywall. (There is a huge argument going on right now about how publicly funded research should be available to the public immediately, and not hidden behind a paywall to benefit a third party (publishers, who provided a much more useful service before the Internet.))

Anyway, it mostly says "we have tested a ton of approaches to prediction and prevention, and none of them really work regardless of what you may have heard in the past, and we really need to find something that works for at least 48 hours to get steroids into play so fewer people are dying, kthx."

The hypertensive syndromes of pregnancy are among the leading causes of maternal and fetal morbidity and mortality and anti-hypertensive treatment is part of the therapeutic arsenal used to prevent serious complications. Although the role of utero-placental insufficiency due to deficient migration of trophoblasts to the spiral arteries is universally accepted, the pathophysiology of PE remains largely unknown and is the subject of debate. No effective ways of predicting or preventing PE have been found, which highlights the need for further research in this field.

This is a hard target. Would that we were dealing with something as "simple" as polio.

[i]The hypertensive syndromes of pregnancy are among the leading causes of maternal and fetal morbidity and mortality and anti-hypertensive treatment is part of the therapeutic arsenal used to prevent serious complications. Although the role of utero-placental insufficiency due to deficient migration of trophoblasts to the spiral arteries is universally accepted, the pathophysiology of PE remains largely unknown and is the subject of debate. No effective ways of predicting or preventing PE have been found, which highlights the need for further research in this field. [/i]

http://www.ncbi.nlm.nih.gov/pubmed/22579836

This is a hard target. Would that we were dealing with something as "simple" as polio.