This is pretty good! Your anatomy is just great, (I can't draw people lol) the hands are soo good! The wrinkles in the sweater are where you should see wrinkles on a sweatshirt and the hair itself is just great!

Small details: The fingernails are a little long unless that's the actual length of your fingernails, then it's understandable. Maybe you should've been more detailed in your hair, like making it seem a little less jaggy since the other parts of your drawing looks realistic in a way. Also, I know it's probably hard but make the shading less obvious, unless your doing soft shading that's just showing the shading/light that's not blurred in.And lastly, your line art could be use some work, less sketch-lines and more clean lines. x3