Fusion

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PCNA

Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (260 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

MCM3

MCM4

Phatr51597

Phatr51412

Predicted protein; Belongs to the MCM family

DNA helicase; Belongs to the MCM family

0.998

MCM3

MCM5

Phatr51597

Phatr11490

Predicted protein; Belongs to the MCM family

Predicted protein; Belongs to the MCM family

0.998

MCM3

MCM7

Phatr51597

Phatr13243

Predicted protein; Belongs to the MCM family

Predicted protein; Belongs to the MCM family

0.998

MCM3

PCNA

Phatr51597

Phatr29196

Predicted protein; Belongs to the MCM family

Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand

0.996

MCM3

Phatr1690

Phatr51597

Phatr1690

Predicted protein; Belongs to the MCM family

Predicted protein

0.994

MCM3

RFC2

Phatr51597

Phatr49374

Predicted protein; Belongs to the MCM family

Predicted protein

0.913

MCM3

RFC3

Phatr51597

Phatr50732

Predicted protein; Belongs to the MCM family

Predicted protein

0.970

MCM3

RFC4

Phatr51597

Phatr9547

Predicted protein; Belongs to the MCM family

Predicted protein

0.961

MCM3

RFC5

Phatr51597

Phatr11922

Predicted protein; Belongs to the MCM family

Predicted protein

0.980

MCM3

RPA2

Phatr51597

Phatr32940

Predicted protein; Belongs to the MCM family

Predicted protein

0.933

MCM4

MCM3

Phatr51412

Phatr51597

DNA helicase; Belongs to the MCM family

Predicted protein; Belongs to the MCM family

0.998

MCM4

MCM5

Phatr51412

Phatr11490

DNA helicase; Belongs to the MCM family

Predicted protein; Belongs to the MCM family

0.998

MCM4

MCM7

Phatr51412

Phatr13243

DNA helicase; Belongs to the MCM family

Predicted protein; Belongs to the MCM family

0.998

MCM4

PCNA

Phatr51412

Phatr29196

DNA helicase; Belongs to the MCM family

Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand

0.997

MCM4

Phatr1690

Phatr51412

Phatr1690

DNA helicase; Belongs to the MCM family

Predicted protein

0.998

MCM4

RFC2

Phatr51412

Phatr49374

DNA helicase; Belongs to the MCM family

Predicted protein

0.914

MCM4

RFC3

Phatr51412

Phatr50732

DNA helicase; Belongs to the MCM family

Predicted protein

0.847

MCM4

RFC4

Phatr51412

Phatr9547

DNA helicase; Belongs to the MCM family

Predicted protein

0.978

MCM4

RFC5

Phatr51412

Phatr11922

DNA helicase; Belongs to the MCM family

Predicted protein

0.937

MCM4

RPA2

Phatr51412

Phatr32940

DNA helicase; Belongs to the MCM family

Predicted protein

0.946

page 1 of 6

Network Stats

Network Stats analysis is still ongoing, please wait ...

Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: