Atropine and its salts, obtained from Belladonna,
are prepared for use by trituration.

Physiological Action

similar to Belladonna.

Allied Drugs :- ►

Bell.,
Hyosc., Stram., Sulphur, (Secale c.).

Generalities :- ►

Appears full
and stupid. ► Convulsions ; especially of limbs ;
beginning in neck and face. ► Clonic spasms of biceps flexor cubiti
and of muscles of jaw, agg. by disturbing the patient. ► Clonic
cramp in face and limbs (moves arms forward in front of chest). ►
Staggering, then falling, with convulsive movements of limbs, then pupils
much dilated, heart beating rapidly, tongue curled to roof of mouth, lips,
mouth and throat dry, convulsions about once in five minutes,
glossopharyngeal not responsive to tickling. ►
Twitching in head and arms, with vomiting, face red, then pale,
pleasant delirium, head thrown from side to side, fingers closed, arms
flexed, convulsions of upper limbs, looking as if deeply drunk, after
three hours clonic spasms over whole body, passing into toxic ones, pupils
dilated, no reaction, difficult deglutition, voice hoarse and thick, skin
insensible, dry, bluish-white, no fever, pulse small, frequent, soft,
irregular, intermittent, respiration accelerated, superficial.

►

►
Jerkings ; especially in legs, arms and face, when
attempting to drink the arm contracted suddenly and the water was spilled,
and when walking one or both legs contracted, throwing one to the ground.
► Hands tremulous and eyes closed, but she became quiet and drowsy,
then kicking and throwing her arms about, limbs weak, unable to stand,
face flushed, then meddlesome and pleasant delirium, picked at her
clothes, tried to get out of bed, imagined she was sewing, nursing her
child or shopping with her sister, then repeated sighing and yawning, then
unconsciousness and stupor, eyes closed, pupils dilated, muscular system
relaxed, except trismus, deglutition almost impossible, respiration
labored and like that of an intoxicated person, lids closed, conjunctivæ
injected, eyes brilliant and staring, tongue, hard and soft palates glazed
and parched. ► Face flushed, pulse full, strong, hard and bounding,
respiration almost stertorous, somnolency, impairment of senses, when
aroused and raised up he would look around wildly, and when addressed in a
loud voice muttered incoherent words, tremor, weakness, especially of
lower limbs, so that he was unable to stand, though there was considerable
strength in his arms, involuntary micturition. ► Convulsive
trembling of one or another muscle.

►

►
Startings in women ; S. at any sudden noise ; at
night when nearly asleep as if frightened (Bell.,
Sul.). ► Busy with his hands, pulling the bed-clothes
about. ► Restlessness ; in morning on rising and
unrefreshed ; with agitation of body and mind ; with
sleeplessness ; with haste, becoming a desire to fight. ►
Impossible to keep him in bed and difficult to keep him from walking
about. ► Sensitiveness ; to sounds and objects at night, with
symptoms akin to early stage of meningitis, in morning rapid pulse, furred
tongue and hot, dry skin. ► General discomfort. ►
Weakness ; morning on rising ; in morning, lay in a half-dreamy
sleep and after dressing great desire to lie down again ; in
open air ; during stool, with nervousness, general
discomfort and sweat ; and trembling all over. ► Faintness and
need of fresh air. ► Anæmia.

►

Motion difficult, and when I raised my
arms they fell as if made of lead. ► Heaviness, drowsiness or actual
sleep, with tendency to dreamy delirium. ► Numb or crawling
sensation formication, down back, on arms and backs of hands. ►
Torpor and paralytic trembling. ► Anæsthesia (Abs.,
Acon., Bell., Sec. c.) ; and water glides over skin
without moistening it or producing sensation. ► Lost the power to
estimate distances either by eye or touch touching an object produces no
sensation. ► Better sitting or standing than lying.

Clinical :- ►

It has
been used homopathically for neuralgias ; supraorbital, agg.
emotion ; earache ; neuralgia under the knee, amel. warm
warps, etc. ► It has sometimes been prescribed for the symptoms of
Bell.,
especially in meningitis, spinal irritation.

Mind :- ►

►
Delirium, with restlessness ; agg. at night, with
agitation ; with drowsiness ; followed by or alternating with
stupor. ► Meddlesome D. ► Frightful phantasies. ►
Spectral illusions at night. ► Struggling to rise from bed (Bell.).
► Jumping out of bed and insisting on dressing himself. ►
Resists being undressed, saying continually that he shall lose the train.
► Restless and unmanageable, refusing to answer, swallow or to be
examined and appeared profoundly intoxicated. ► Delirious and
restless, talking constantly about his affairs. ► Talked almost
unintelligible nonsense in morning on waking. ► Attempts to reason.
► Insisted that her blood did not circulate, and that her feet must
be put into hot water or she would die. ► Answer imaginary
questions. ► Talked and laughed wildly, but answer questions readily
fancying that they were at home and attempting to arrange furniture.
► Returned answers when addressed, whose beginning showed that he
understood, but which passed into irrelevant, senseless talk. ►
Incoherent quarreling. ► Delirium after a chill, resembling the
subdelirium of certain typhoid fevers. ► Busied with subjects which
at other times occupy his mind, politics and struggles consequent on his
relations in life. ► On closing eyes after retiring, mind filled
with strange ideas, rambling incoherent speech, spectral illusions, with
fits of wild, uncontrollable laughter, the delirium lasting all night,
fancied that I was afflicted with epilepsy and afraid other would discover
my condition, nearly oblivious of all that transpired the latter part of
the night, but known from bruises and pains from contact with a stove,
chair or some solid body that it was passed in the wildest delirium.

►

►
Delirium resembling delirium tremens ; incessant rambling
restlessness, grasping at imaginary objects and screaming from fright,
terror was depicted on his face, and he clung to his nurse's neck or he
threw himself in different directions to escape the frightful objects (Stram.)
later the delusions were pleasurable, of playing with toys, drawing
eating, etc. ► Pleasing illusions, meddling with everything, picking
at and handling imaginary objects, with muttering and smiling, or with
loud chattering interrupted by subdued laughter. ► Hallucinations,
grasping at imaginary objects, with staggering rapid full and strong
pulse, drowsy stupid, answered in an indistinct tone but rationally,
afterwards coma increased, head hung upon his shoulders in a limp state,
unconscious, respiration ceased and artificial respiration was resorted
to. ► Picking at specks and at the air, on lying in bed. ►
Picking at bed-clothes, as if searching for something at night, with
confused mutterings (Hyos.). ►
Incoherent quarreling. ► Frenzied with excitement. ► At times
when it seemed to him as if he were fully conscious he saw persons at the
bedside, and slowly reached out to grasp them, or saw books and newspapers
which receded, or the hand would come in contact with them and feel
nothing. ► Felt a wet cloth on my head, but supposed I had been out
in the rain without a hat, etc., etc.

Motion unpleasant, and if feet were
lifted in walking the floor seemed to recede before they were put down
again, a sliding of the feet seemed the only safe way of locomotion, with
dizziness and fear of falling, great thirst, but only a little water could
be drunk at a time because swallowing was unpleasant, languid feeling a
semi-recumbent position was assumed, and whether sleep with wild dreams or
waking hallucinations followed it was impossible to tell, but they were
the opposite of those produced by Cannabis indica,
for all the imaginations and conversations were of the long past, whether
there was total blindness or imagination of blindness could not be
remembered, but all the images were very distinct, the actions were
performed by embodied spirits of those long since departed, and lengthy
pleasant conversations were held with Plato, Alcibiades, Aspasia and
other, sound sleep must have followed, for consciousness did not return
till sixteen hours after taking the Atropia, then sudden waking, with
nothing abnormal but languor and disturbed vision. ► Loud cries
without pain.

►

Fretful. ► Desire to scold and
quarrel, alternating with internal anxiety and fear, changing at last to
anguish. ► Morose, quarrelsome, angry at trifles. ► Sudden
fear of death, with nervous excitement and formication all over body.
► Apprehension after his internal restlessness, soon amounting to
anxiety. ► Sadness ; with anxiety, restlessness and fear of
misfortune, or angry and inclined to be alone, seldom lively. ►
Cheerful to an exaggerated degree. ► Indolence of mind ; then
vertigo, then beginning intoxication. ► Want of memory. ►
Memory wrong, thinks what happened in the night of the 11th took place in
the night of the 10th. ► Attention difficult to fix. ►
Absent-minded ; and forgetful, after partly finishing a sentence was
obliged to inquire what I had been saying. ► Feels as if awakened
from a dread. ► Confusion of mind when he closes his eyes, and all
sorts of spectres. ► Dull and not inclined to move about or
converse ; when spoken to often turn his
head to the wrong side. ► Unconsciousness ; with
incoherent talking ; and irritability, striking his mother when she
took him from the nurse. ► Comatose ; and insensible, with
dilated pupils and flushed and swollen face ; with cyanotic and cool
skin, pale face, livid lips ; relaxed limbs jaw hanging down, mouth
and tongue dry, pupils dilated, insensible, respiration slow, pulse 90.

►

► Head
and face flushed and hot, with full, bounding, irregular pulse. ►
Sticking in base of skull and especially over eyes on every motion and
agg. stepping. ► Feeling as if screwed up, and walking caused
sticking. ► Aching ; with vertigo, pain in back and
nausea ; with vertigo on sudden motion ; sick headache, with
pain in right eye and right temple. ► Fulness and discomfort ;
skull feels too small for brain, pain in vertex and over eyes, pain in all
that part of head above eyes, head feels as if it would burst. ►
Dull feeling with feeling as if hair were matted into a thick felt. ►
Confusion in morning as after a disturbed night, amel. open
air ; dizzy, evenings, alternating with vivid phantasies, with
general fatigue and at times ringing in ears. ► Intoxicated feeling,
afraid to walk, must concentrate the mind to keep from falling,
staggering.

►

Vertigo ; in morning on rising, so
that it became dark before his eyes ; on waking ; on waking,
agg. rising, with confusion of head ; on waking, with staggering
towards objects for support ; on turning head quickly ; when
attempting to walk ; with wanderings of vision ; with weight on
vertex and over eyes ; with pressure in temples, with little or no
pain ; with strange feeling in head, so that he could not see, throat
deep red, sore, with inability to swallow ; with heaviness,
drowsiness or sleep, tendency to dreamy delirium and in women
startings ; intermittent ; intermittent in forenoon.

Forehead :- ►

►
Intermittent fine drawing stitches across F. and temples.
► Aching ; amel. closing eyes ; headache beginning in
middle of F. ; in anterio-superior cerebral region ; with
vertigo on moving suddenly. ► Fulness, with heat of head ; in
anterior part of brain ; in front part of head, with dilatation of
pupils.

Temples :- ►

►
Stitching in left in morning on waking, extending behind ear, scarcely
permitting him to open left eye, amel. moving about in open air.
► Aching ; and in eyes ; intermittent,
like a deep heavy pressure, and at other times tension in anterior
cerebral region, as if brain pressed out in all directions. ►
Pressure from without, agg. right. ► Bruised feeling. ►
Fulness ; in T. and forehead, with pain and with vertigo so that one
can scarcely walk. ► Throbbing.

►

Pressure under parietal bones. ►
Throbbing in vertex.

Eyes :- ►

Restless. ►
Projection from sockets. ► Congested ; and glassy. ►
Fixed and glassy. ► Aching ;
and in head ; and in temples ; with lachrymation ; in back
part ; with fulness and pressure in anterior part of head, making me
restless, with sleeplessness till near morning. ► Swollen feeling,
and the pain in eyes and temples agg. with each pulsation of the heat.
► Eyes and lids sore to touch. ► Dryness. ► Intolerance
of light. ► Weariness.

►

Pain in left ball. ► Pressure from
without in every direction in ball. ► Pupils immovable ; and
dilated ; dilated, with diplopia ; dilated, with clouded vision,
images confused, with a reddish tinge. ► Lids swollen ; red and
excoriated skin of lids ; erysipelas of lids spreading to face and
head ; inflammatory swelling of mucous membrane of eyes, with
muco-purulent secretion, often with swelling of lachrymal sac,
occasionally with less swelling but more marked hyperæmia and
lachrymation ; lids heavy and difficult to
keep open about 9 P.M.
without sleepiness ; lids ache ; lids feel sore and are red.
► Glaucoma of right. ► Congestion ; with dryness of the
conjunctiva and aching in ball ; erysipelatous inflammation and
swelling of conjunctiva and lids ; conjunctivitis. ►
Sharp pain under right eye with aching in temples. ► Intermittent
neuralgic pain under left orbit running back to ear.

►

Vision and hearing morbidly
sensitive ; at night. ► Difficult vision with right eye ;
D., of small, near objects. ► When talking with persons they
suddenly vanish. ► After looking at objects a few minutes they
become indistinct ant fade away. ► Letters run together after
reading a little. ► Eyes lost control of distance, print held at
usual distance was blurred at a long distance letters could be
distinguished but words soon ran into confusion, distant objects were
plainer than natural, but near objects soon became indistinct and light
caused pain deep in balls. ► Partial blindness, with one pupil twice
as large as the other. ► Partial color-blindness. ► Cannot
estimate distances correctly. ► Staggering, catching at distant
objects which appeared near and often stumbling over objects which
appeared distant. ► Quick rotation and duplication of objects.
► Dim V. ; with golden circles dancing before eyes. ►
During the increasing dimness illusions of gigantic figures, whirls,
double images, enlarged appearance of all objects and laughable or
frightful appearances of all kinds. ►
Diplopia. ► The large figures on the carpet seemed to be
constantly and successively rising to her face (perpendicular diplopia,
the apparent objects below the real one). ► Round or oval objects
seem elongated ; the vertical diameter of the human face seemed equal
to the rest of the body, especially prominent were the nose and chin, with
their margins enveloped in mist, next day pupils large and sluggish.
► Eyes of attendant seemed very large. ► Letters of a
newspaper seemed to expand and contract with each pulsation of heart.
► Objects appear enveloped in a white vapor. ► Vision of many
white flies on the door, which was white, at night, continued till next
noon, on closing eyes. ► Bright spots and stars and a brilliant glow
around letters. ► Bright flashes at night on closing eyes. ►
V. of a black bug, with veritable legs, below a black door knob. ►
V. in morning of a thousand-legged brown worm on carpet, the predominating
color of which was brown.

Teeth and lips dry and
covered with sordes. ► Teeth feel "on edge." ►
Tongue trebles when protruded ; with light redness of tip and edges.
► Tongue coated dirty gray ; white ; whitish on margins
and yellow in middle ; T. thick, cannot articulate distinctly.
► Tongue dry ; and coated mucous layer dry, brown and
hard ; anterior part of whole of dorsum, except a wide margin, dry
brown and rough ; dorsum of T., roof of mouth and velum palati dry
and glazed ; feeling as "dry as a chip," though moist to
sight and touch, and the throat seemed almost as if its sides were stuck
together ; and hard and soft palates, extending down pharynx and
larynx, making voice husky and often inducing dry cough and difficult
deglutition. ► Tongue and mouth dry and feverish and throat dry,
amel. for only a short time by water, the dryness of throat increased,
causing at first frequent deglutition, afterwards strong effort to avoid
swallowing, which had become painful. ► Tongue partially paralyzed.
► T. difficult to protrude and cannot be moved about in mouth at
will. ► T. and other muscles assisting in speech difficult to move.
► Stuttering, especially at words difficult to pronounce. ►
Slowness and embarrassment of articulation. ► Articulation
indistinct, rapid and chattering. ► Speech thick, probably from
dryness of mouth and throat.

►

Mucous membrane red. ► Hard and
soft palates completely, glazed. ► Thick, viscid or slimy mucus.
► Coating of viscid, slimy, white mucus. ► Mouth and throat
feel as if she could not swallow, but she drank with avidity warm water,
though it seemed difficult at first. ► Formication on palate.
► Buccal cavity feels hot. ► Dryness ; at night,
especially along median line and on each side of it. ► Hard and soft
palates and back of sophagus as dry and glazed as a piece of paper.
► Dryness ; of M. and throat, with sensation of burning and
choking and difficult swallowing ; D. suddenly amel. by a viscid acid
secretion, of offensive odor, like sweat of feet, the mouth becomes foul
and clammy, with a bitter coppery taste ; but no thirst, and
inability to feel passage of water through mouth and throat. ► No
sensation in M. and throat when drinking water except slight coldness.
► Loss of sensation in buccal cavity, with loss of taste.

Nausea ; in morning, with vomiting.
► Ineffectual retching. ► Vomiting
after warm drinks ; after milk ; of food after dinner ;
profuse V. of colorless mucus, then of green, bitter fluid after the
morning vertigo. ► Nervous and wakeful for three hours, hurried from
bed and vomited profusely a watery fluid, bitter at first, nearly
tasteless, afterwards with sticking in umbilical region. ►
Constrictive pain caused by beer, agg. walking, with eructations of air
and nausea. ► Distress in epigastric region. ► Feeling in
night as if the stomach had got a grip of the apple eaten in the evening
and would hold it as in a vise. ► Sensitiveness to strong pressure. ►
Soreness of pit. ► Discomfort. ► Burning. ►
Uneasiness, with empty eructations, then with nausea and retching,
increasing to a pressing sticking and contractive pain, with pallor and
sweat of face, singing in ears and aching in forehead.

Râles about base,
pain over right side of, cough, with rust-colored and scanty
expectoration, dullness of chest as far as spine of scapulæ on right side
behind, tubular breathing and bronchophony, rough breathing over left lung
posteriorly. ► Warmth.

Heart :- ►

Fluttering sensation
in cardiac region. ► Palpitation ; at night, with great
debility and distress. ► Action accelerated and pressure of blood
increased by weak doses, the reverse from poisonous doses. ► Action
irregular and apparently obstructed. ► Labored heavily and to my
feeling at the rate of about fifty per minute, with sore feeling over base
of heart.

Pulse :- ►

Rapid ; with
increased force of cardiac contractions and of arterial tone ; with
increased tone but diminished volume ; increased in volume and power,
often with vertigo ; full and soft ; in morning on rising, and
small and irregular, with lassitude ; irregular, generally full but
varying much ; small and compressible ; small and weak ;
with heat. ► Slow ; afterwards rapid ; S., afterwards
small and rapid. ► Weak.

Arms,
hands and fingers thrown about constantly, as in delirium. ► Hands
feel dry and glossy ; numbness of H. extending to finger-tips, with
prickling, afterwards insensibility. ► Fingers numb, with feeling as
if holding a book, which he fears will drop, and on taking a small object
as pain it appears as if there were five of six ; insensibility of
tips.

Lower Extremities :- ►

Gait weak.
► Staggering ; or inability to walk. ► "Limbs felt
like sticks," thought she could not walk across the room, but with
aid did so with difficulty. ► Stiffness of
left knee, left leg and in right great toe. ► Dragged
legs when walking. ► Jerkings of legs ; waking at night.
► Kicking, waking at night.

Skin :- ►

Hands and fingers
suddenly swelled and became stiff while the face was scarlet-red and
eyelids swollen. ► Redness ; like
scarlet fever, over face and upper half of body, skin hot and dry. ►
Feeling as if turgid and swollen, afterwards covered with a rash similar
to that of scarlatina. ► Formication ; preventing
sleep.

Sleep :- ►

Yawning often. ►
Sleepiness, with disinclination to speak or move ; S. with
vertigo ; with perversion of ideas ; with sometimes flushing of
face. ► Waking late in morning, with heaviness and confusion of
head. ► Sleepiness early, but inability to fall asleep, heard every
noise, but could not open his eyes, wearied by diversified dreams, that he
was in a forest followed by serpents, tried to flee, but could only move
with difficulty, the serpents wound only move with difficulty, the
serpents wound themselves about him or crept into his clothes, or a common
play-ball lying on the table increased in size, so that the room could no
longer contain it and it threatened to choke him, or he thought the
masonry work was going to yield on all sides and the house was going to
fall, afterwards covered only with a shirt he came to a place deserted by
people, saw several persons come up to him, tried to flee but could not
because he was lame, these endeavors to escape from danger exhausted him,
and he was glad to be free from this condition when awakened by a loud
cry.

►

Sleeplessness ; till 1 A.M.,
then dreams of people moving about disfigured in such a way that the
perpendicular diameter of the face almost equaled in size the rest of the
body, especially the nose and chin and the contours appeared misty ;
with delirium. ► Unintelligible talking in sleep. ► Short
restless naps. ► Restless sleep, with dreams of running horses, of
playing baseball of amputating a man's arm, of shadowy forms sitting or
standing by the bedside or moving in the air.

►

Dreams and startings, a fancied noise is
a common cause of waking, and at these times the patient generally
manifests a little delirium. ► Frightful dreams waking him,
disconnected, of being murdered, of falling from a height, of being
attacked by large dogs, etc. ► Pleasant D., of flying, etc.

Fever :- ►

Chilliness and cramp,
with tingling of extremities. ► Internal C., agg. towards 6 P.M.
with external heat, apprehension and restlessness, palpitation, anxiety as
if he had committed a crime and sleeplessness till towards 11 P.M.
► Frequent rigors and loss of muscular power, being unable to walk,
or, as he expressed it "to feel his legs." ► Chill
alternating with heat, with tension of chest, dyspna and feeble pulse.
► C. over back alternating with heat (cold predominating). ►
Cold sensation along spine. ► Cold extremities. ► Cold hands.
► Cold skin on forehead and head.