The Indianapolis Colts host the Buffalo Bills in a significant Week 12 throwdown. The Colts need the win to stay on track for a wild-card berth and the No. 5 seed in the AFC, and the Bills need the win to keep their slim playoff hopes alive.

From a morale standpoint, the Colts want to stay on their emotional high and give coach Chuck Pagano as many wins as possible. From the Bills' standpoint, Chan Gailey knows he is coaching for his job, and the Buffalo players want to prove they have the players to make a run.

While both teams are banged up and have some injuries to key contributors, both teams desperately need the win to keep their seasons in tact.