When a comedian says he plays for the lowest common denominator, he usually means it derogatively. Actor/comedian Dave Coulier thinks of it as a way to get everybody in on the fun.

“Lowest common denominator can sometimes apply to me, because that’s what makes me laugh,” says the St. Clair Shores native. “That’s how my family was growing up; my dad was a real pull-my-finger kind of guy. That stuff, in my core, really makes me laugh, and that’s the kind of stuff I try to do.”

Known for his eight years as Uncle Joey on “Full House” and his voice in “The Muppet Babies” and “The Real Ghost Busters,” Coulier returns home for a three-night stand at Mark Ridley’s Comedy Castle this weekend.

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Since “Full House,” Coulier has expanded his stand-up act, where his voice talents have always been key, and he’s working on the second season of “China, IL,” a comedy on Cartoon Network’s Adult Swim.

“I get to play some real weird characters,” he says. “I’ve played Ronald Reagan. I just did an episode where I play God — and God is Matthew McConaughey. So it’s pretty weird, cool, funny stuff.”

He promises his new material will meet expectations.

“It’s very eclectic. There’s some new characters, some new voices, some new premises; just a lot of new material. I don’t think I’ve been at The Comedy Castle for going on two years now, so in that 2-year period there were long stretches of writing things, and now I’m going out and bringing this stuff from the page to the stage,” he says. “It’s one of the things that makes me me. It’s part of my style and I enjoy doing characters and voices and I think people enjoy them, too.”

Coulier is known for keeping his act clean, a the result, he says, of coming up through the ranks in the days of Johnny Carson.

“If you didn’t work clean, you didn’t get on the show because it was national television,” he says. “For me, I don’t think of it as playing safe, I think of it as playing wide, to the widest possible demographic.”

“When I was 19, I was in Los Angeles working at The Comedy Store. Jay Leno saw me perform and he says, ‘Hey, Coulier, I saw your act. Remember, if you keep it clean you can make it anywhere,’” Coulier recalls, doing a spot-on Leno impression.

Coulier helped create The Clean Guys of Comedy Tour — great stand-up that’s accessible to everybody. He and his fellow clean comedians are taking it to the next level in spring with a screen version of The Clean Guys of Comedy.

“We had been touring for a while; we even headlined the Detroit Comedy Festival a while back,” he says. “It was a pretty good success, so I thought that we should try to move forward with this. We took it to some filmmakers and ... it started rolling.”

He says he will finish the year with club dates and college shows before his schedule takes off in the new year to promote the movie.

Coulier says he is always looking toward the future, but remembers his past, particularly his time as Uncle Joey, with great affection.

“Oh, of course, that’s never going to leave me,” he says. “I don’t ever want it to leave me. I’m very proud of the work that all of us have done on that show. It has become an American icon and with it, we’re forever embedded in syndication and history.

“When I first started, every comedian I ever knew or talked to dreamed of being on a show like ‘Full House.’ It wasn’t one of those be careful what you wish for things, it was, ‘Wow, I wished for that and it happened.’ And I sure feel lucky for that.”

Dave Coulier performs at Mark Ridley’s Comedy Castle in Royal Oak, Nov. 1-3, with 8:30 shows all three nights and 10:15 p.m. shows Friday and Saturday. Tickets are $15 Friday and $25 Saturday. For more information, visit www.davecoulier.tv and follow @davecoulier on Twitter.