Oral squamous cell carcinomas (OSCC) around dental implants appear cumulated in patients who have still been diagnosed and have received therapy for oral squamous cell carcinomas. Ongoing cigarette consumption often combined with alcohol abuse also seems to be the main reason for their arising. However a preexisting dental implant induced tissue irritation/peri-implantitis without nicotine or alcohol cunsumption seems to promote the growth of oral malignoms for itself. The clinical problem in identifiying these tumours dues to its mimikry of peri-implant inflammation. In this poster we demonstrate three cases of patients with resected squamous cell carcinomas in the soft tissue of the lower jaw who got dental rehabilitation with implants after at least one year without recurrence of the tumours. In the controls after dental implantation new squamous cell carcinomas occured around these implants imitating peri-implant irritation. Extensive soft and hard tissue resection with explantation of the implants and local adjuvant radiation was proceeded. Up to now (more than two years) the three patients are presenting a relapse free disease process.