Fusion

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CYN28

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type (350 aa)

Predicted Functional Partners:

EDP05779

Predicted protein (150 aa)

0.892

FKB42

Peptidyl-prolyl cis-trans isomerase, FKBP-type (1784 aa)

0.874

RAN1

Ran-like small GTPase; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (223 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

CYN28

CYN57

EDO96608

EDO99336

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

0.817

CYN28

EDP01119

EDO96608

EDP01119

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Predicted protein

0.811

CYN28

EDP01120

EDO96608

EDP01120

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Ubiquitin-like protein

0.811

CYN28

EDP05779

EDO96608

EDP05779

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Predicted protein

0.892

CYN28

FKB42

EDO96608

EDP06958

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Peptidyl-prolyl cis-trans isomerase, FKBP-type

0.874

CYN28

PRP19

EDO96608

EDP06795

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Spliceosome component, nuclear pre-mRNA splicing factor

0.827

CYN28

RAN1

EDO96608

EDP04368

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Ran-like small GTPase; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle

0.849

CYN28

STM2

EDO96608

EDO99834

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Ubiquitin-like protein

0.811

CYN28

TOP2

EDO96608

EDO98265

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

DNA topoisomerase II; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks

0.828

CYN28

XAB2

EDO96608

EDO96712

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Transcription-coupled DNA repair protein

0.814

CYN57

CYN28

EDO99336

EDO96608

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

0.817

CYN57

EDP01119

EDO99336

EDP01119

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Predicted protein

0.652

CYN57

EDP01120

EDO99336

EDP01120

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Ubiquitin-like protein

0.652

CYN57

EDP05779

EDO99336

EDP05779

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Predicted protein

0.972

CYN57

FKB42

EDO99336

EDP06958

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Peptidyl-prolyl cis-trans isomerase, FKBP-type

0.788

CYN57

PRP19

EDO99336

EDP06795

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Spliceosome component, nuclear pre-mRNA splicing factor

0.927

CYN57

RAN1

EDO99336

EDP04368

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Ran-like small GTPase; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle

0.742

CYN57

STM2

EDO99336

EDO99834

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Ubiquitin-like protein

0.652

CYN57

TOP2

EDO99336

EDO98265

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

DNA topoisomerase II; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks

0.828

CYN57

XAB2

EDO99336

EDO96712

Peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Transcription-coupled DNA repair protein

0.837

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: