Anyone else having this issue?

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My skillpoints are randomly removing them selves at random times, like time i will have all modded skills maxed, then next time i load the save i have 46 skill points and the skills are all refreshed? O_O

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I had started a conversation about this a while ago: http://www.xpgamesaves.com/topic/49753-discussion-on-modding-bl2-gpd/page__p__218817#entry218817

It's because the GPD on online profiles (gold accounts) have two hash keys in them that verify against corruption and tampering..
So if you try to use a GPD without those hash keys in a online profile that it doesn't belong to then your GPD will be replaced by whatever GPD is backed up in your XBL backed up GPD (what they have on record). Again.. if those hash keys don't pass the test then it's a no go for online. You may be able to mod your online GPDs on jtags though... there's some services around (on here) that may provide that for you.