Emergency treatment: "Linalool"; [HSDB] Included in list of "established contact allergens in humans"; [ToxPlanet: EC: Scientific Committee on Consumer Safety: Fragrance allergens in cosmetic products (2011)] Causes somnolence and ataxia and acts as a general anesthetic in lethal dose studies of rats; [RTECS] Safe when used as a flavoring agent in food; [JECFA] Hydrolyzed in the GI tract into linalool and acetic acid; Not a mutagen; Not likely to be a sensitizer; Linalool, a hydrolysis product, caused "hepatocellular cytoplasmic vacuolisation" in 28-day feeding studies of rats; [Reference #1] See "Linalool."

Sources/Uses

Comments

Emergency treatment: "Linalool"; [HSDB] Included in list of "established contact allergens in humans"; [ToxPlanet: EC: Scientific Committee on Consumer Safety: Fragrance allergens in cosmetic products (2011)] Causes somnolence and ataxia and acts as a general anesthetic in lethal dose studies of rats; [RTECS] Safe when used as a flavoring agent in food; [JECFA] Hydrolyzed in the GI tract into linalool and acetic acid; Not a mutagen; Not likely to be a sensitizer; Linalool, a hydrolysis product, caused "hepatocellular cytoplasmic vacuolisation" in 28-day feeding studies of rats; [Reference #1] See "Linalool."