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MADRID (Reuters) - Jose Mourinho wrote off Real Madrid's chances of overhauling Barcelona to retain their La Liga title after being held to a surprise 2-2 draw at home by struggling Espanyol on Sunday.

Unbeaten leaders Barca went on to hammer second-placed Atletico Madrid 4-1 with a double from Lionel Messi at the Nou Camp in the late game and moved 13 points clear of third-placed Real after 16 games.

"It is practically impossible," Mourinho told a news conference about their title hopes.

"That's too much (of a gap) at this stage. Last year we had a 10-point advantage in February or March and we were able to maintain it.

"But if we can improve in the league it will serve to help us in the King's Cup and the Champions League."

Real have struggled to replicate their record-breaking performances from last year and have already dropped 15 points with three draws and three defeats, one more than in the whole of last season.

Barca have won every league game except for the 2-2 draw at home to Real back in October.

Real's surprise 2-1 defeat at Celta Vigo in a King's Cup last-16 first leg in midweek has led to renewed speculation that Mourinho will not see out his contract at the Bernabeu which runs until 2016.

"I have never seen a situation like this before, losing so many points, and having a team so far from its objectives," Mourinho added.

"It's new for me, but I am not about to give up. I am not going to make a drama of it. We will seek to finish the season in the best way possible.

"We have titles within our reach and we have to fight for them, but the league is almost impossible now."

After having seen off their closest rivals Atletico, Barca were keen to play down their points advantage over the Madrid clubs.