Hephaestus is the main power production facility for Rapture and is located at the base of the city, harnessing the heat from geothermic vents on the ocean floor. Without Hephaestus, Rapture could not have been built. The workshops are used by the mass of engineers and workers who maintain the city. Hephaestus has also been known to be prone to sabotage by the oppressed people.

The Medical Pavilion was the hub for all medical business, however, as ADAM became widely distributed, its self-healing abilities removed the need for healing facilities. Now, due to the instability of ADAM and the physical mutations that occur, many hospital facilities have now been replaced by cosmetic surgery facilities such as Dandy Dental and Dr. Steinman's Aesthetic Ideals.

Neptune's Bounty is the fishery in Rapture and is used heavily by Frank Fontaine and his men to smuggle equipment from the surface. The Wharf in Neptune's Bounty is by far the largest and busiest area. Upper Wharf is the connection point where the workers can reach the Wharfmaster, the Jet Postal or the Fighting McDonagh's after a hard day at work.