The primary objective will be, in an open-label randomized trial, a comparison of emergency department (ED) length of stay (LOS) between children experiencing acute asthma treated with two different nebulizers

to evaluate admission rates.

242

All

3 Years to 17 Years (Child)

NCT01951378

CR-13-119

September 2013

June 2016

July 2016

September 26, 2013

October 13, 2016

Dell Children's Medical Center of Central TexasAustin, Texas, United States

To compare percentage (%) of responding children by the end of 6-month observation. Responders are defined as children with adequate control of symptoms at the end of 6 months observation (Childhood Asthma Control Test (CACT) score > 19)

To determine mean number of severe bronchial asthma exacerbations within 6 months

To determine mean duration of bronchial asthma exacerbations including hospital admissions, daytime hospital treatment and any cases of oral administration of glucocorticoids > 3 consecutive days during the observation period

Number of participants out of the total experiencing asthma worsening as assessed by changes in peak expiratory flow, FEV1, rescue medication use, and ACQ-5 score, and the occurrence of severe asthma exacerbations.

480

All

18 Years to 74 Years (Adult, Older Adult)

NCT03683576

GB001-2001

October 22, 2018

June 30, 2020

July 31, 2020

September 25, 2018

February 15, 2019

Clinical Research Center of Albama, LLCBirmingham, Alabama, United States

California Allergy and Asthma Medical GroupLos Angeles, California, United States