General Info

Alternative names

CD142

CD142 antigen

Coagulation factor III

Coagulation factor III (thromboplastin tissue factor)

F3

FLJ17960

TF

TF_HUMAN

TFA

Thromboplastin

Tissue factor

see all

Function

Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.