Rob LoweThere's No Replacing Regis!

1/7/2012 6:06 AM PST

Rob Lowe -- There's No Replacing Regis Philbin

Our photog asked Rob Lowe straight up yesterday at LAX -- would he be interested in taking over Regis Philbin's chair next to Kelly Ripa -- and he certainly didn't give us a straight answer.

As TMZ first reported, ABC loved the chemistry between Rob and Kelly during his two-day guest hosting stint this week and have already approached the "Parks and Recreation" star to gauge his interest in coming aboard full-time.