115 - The Pork Chop Indeterminacy
Aired May 5, 2008

Sheldon's attractive twin sister, Missy, is in town and the guys can't avoid hitting on her. As they all vie for Missy's affections, Leonard devises a plan to eliminate his rivals. Eventually, Sheldon decides he should determine who can date his sister. Meanwhile, Raj takes part in a drug trial to try overcome his selective mutism.

Episode Pictures (6)

Recap

When Sheldon's sister comes to town, Sheldon reluctantly lets her stay at his apartment instead of the hotel she had booked. Leonard, Howard and Raj are all smitten by Sheldon's twin, Missy, and compete with each other to win her fancy. When Raj's selective mutism prevents him from talking to Missy, he signs himself up for an experimental drug.

After being creeped out by the guys' advances, Missy goes out with Penny to get their nails done. In a sneaky effort to try win over his sister, Leonard tells Sheldon he should be taking an interest in who Missy is with in order to protect her genetic lineage, which could one day produce another remarkable intellect like Sheldon's. Sheldon accepts Leonard's argument but instantly dismisses all three of the guys as unsuitable for his sister.

When Missy witnesses Sheldon telling the guys they're not good enough for her, she demands to see Sheldon in his room where she explains he does not have a say in who she dates. Sheldon informs the guys he no longer has any say in the matter, and they decide to vie for Missy's affection in a more restrained manner.

Leonard, Howard and Raj each visit Missy, who is now staying in Penny's apartment, to try win her over. Only Raj seems to have made a positive impression on her, though his efforts are for nought when his medication wares off and he can no longer speak to her. Missy returns to Texas with none of the guys having successfully courted her.