Haem exporter protein D (CcmD) (IPR007078)

Short name:
Haem_export_protD_CcmD

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

The CcmD protein is part of a C-type cytochrome biogenesis operon [PMID: 7635817]. CcmD interacts with CcmE and CcmC, establishing a cytoplasm to periplasm haem delivery pathway [PMID: 10998170, PMID: 15513913]. CcmD is a component of the CcmABC ATP-binding cassette transporter complex. It is not necessary for the CcmC-dependent transfer of heme to CcmE in the periplasm but it is required for the release of holo-CcmE from the CcmABCD complex [PMID: 18326572].

Schulz H, Pellicioli EC, Thony-Meyer L.
New insights into the role of CcmC, CcmD and CcmE in the haem delivery pathway during cytochrome c maturation by a complete mutational analysis of the conserved tryptophan-rich motif of CcmC.Mol. Microbiol. 37 1379-88 2000