Abstract

Enantiopure benzylic alcohols containing two stereogenic centres in a cis-relationship result from stereoselective monohydroxylation of achiral 2-substituted indans in cultures of Pseudomonas putida UV4 and are used in the chemoenzymatic synthesis of both cis- and trans-aminoindanol enantiomers. (C) 1996 Elsevier Science Ltd