In this Friday, Aug. 24, 2012 file photo, U.S. Rep. Todd Akin, R-Mo., addresses members of the media in Chesterfield, Mo., where he confirmed his plans to remain in Missouri's U.S. Senate race despite a political uproar over remarks he made about rape and pregnancy.

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A game of political chicken is playing out among the nation's top Republicans and Missouri's embattled GOP nominee for the Senate. Will Rep. Todd Akin eventually cave to party leaders' demands and drop his challenge to Democratic Sen. Claire McCaskill?