CArdiac Desynchronization In Obstructive HCM, CARDIO-HCM (CARDIO-HCM)

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The purpose of this study is to evaluate the benefit of the optimal pacing configuration, including the possibility of biventricular or left ventricular pacing, in hypertrophic obstructive cardiomyopathy patients.

Condition or disease

Intervention/treatment

Phase

Hypertrophic Obstructive Cardiomyopathy (HOCM)

Device: Biventricular pacingDevice: No Pacing

Phase 2

Detailed Description:

In this study, subjects will be randomized to Cardiac Resynchronization Therapy-Defibrillation (CRT-D) or Cardiac Resynchronization Therapy-Pacing (CRT-P) vs Pacing Therapy AAI. Randomization will be stratified by indication. Optimal pharmacological therapy in both treatment arms. Length of follow-up for each subject will be 2y, since all subjects will be followed to a common study termination date.

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