Patch tests performed with formaldehyde challenge concentrations of1% or less resulted in positive reactions in about 2% of all patientstested throughout the world; higher formaldehyde challenge concen-trations may be irritant (Anon., 1987).

(1961) The reaction of formaldehyde withpolynucleotides.

There is no evidence in the literature of allergic reactivity ofthe mucous membranes of the eyes being caused by airborne formaldehydeor by formaldehyde solutions.

Mechanism of the initial reaction of formaldehydewith DNA.

(1979) Reaction of formal-dehyde with calf-thymus nucleohistone.

It has been shown that sensory irritation is the earliest humanreaction to formaldehyde, both in exposure studies and from complaintsabout indoor environments.

Hantzsch Dihydropyridine (Pyridine) Synthesis

Since differences in indi-vidual reactions to formaldehyde are large in both the normal popu-lation and in hyperreactive and sensitized persons, it is difficult toestimate a concentration guaranteed not to produce negative reactionsin the general population.

Hantzsch pyridine synthesis - overview - ChemTube3D

In the exposure chamber, a bis-chloromethyl-ether (BCME) concentration of 0.5-2 µg/m3, due to the chemicalreaction of formaldehyde and hydrogen chloride, was estimated.

Hantzsch Dihydropyridine Synthesis

Allergic reactions to cosmetics containing formaldehyde as a pre-servative, especially shampoos, are unusual (Eckardt, 1966) and appearmostly among those who have been sensitized by occupational exposure.

Pyridine synthesis - Organic chemistry

9.2.4.4 Systemic sensitization A case report has been described involving an anaphylactic shockreaction after accidental iv application of formaldehyde duringhaemodialysis treatment due to formaldehyde remaining in the equipmentafter disinfection.