The aim of this paper is to describe and discuss the results of numerical comparative study performed in order to demonstrate and quantify some of the most relevant non-Newtonian characteristics of blood flow in medium-sized blood vessels, namely its shear-thinning and viscoelastic behavior. The models studied in this work are the classical Newtonian and Oldroyd-B models, as well as their generalized (shear-thinning) modifications. Numerical tests are performed on three-dimensional geometries, namely an idealized axisymmetric stenosis and a realistic stenosed carotid bifurcation reconstructed from medical images. The numerical solution of the system of governing equations is obtained by a finite-volume method on a structured grid. Model sensitivity tests are achieved with respect to the characteristic flow rate to evaluate its impact on the observed non-Newtonian effects.Trvalý link: http://hdl.handle.net/11104/0200004