I have seen many V10s with super charger and I don't see any reason why it won't handle it. I don't know of anybody on FTE with a V10 supercharged other then a guy with an excursion he signs as Gary in Alaska or Canada I forgot which one but forgot his username. Look for the regular things when looking at a vehicle and it should be ok. I am not sure I can find the username or not of that user but will try.

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