Previous GeneCards Identifiers for GANC Gene

Summaries for GANC Gene

Entrez Gene Summary for GANC Gene

Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1,4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2014]

GeneCards Summary for GANC Gene

GANC (Glucosidase Alpha, Neutral C) is a Protein Coding gene.
Among its related pathways are Galactose metabolism and Metabolism.
GO annotations related to this gene include carbohydrate binding and alpha-1,4-glucosidase activity.
An important paralog of this gene is GANAB.

UniProtKB/Swiss-Prot for GANC Gene

Tocris Summary for GANC Gene

Glycosylases are a group of enzymes that includes glucosidases, mannosidases and heparanases. There are two glucosidase subtypes, both found in the gut. They hydrolyze terminal (1,4)alpha-glucosidic linkages and (1,6)beta-glucosidic linkages, liberating alpha-glucose and beta-glucose.

Relevant External Links for GANC

No data available for
MalaCards ,
UniProtKB/Swiss-Prot and
Genatlas
for GANC Gene

Publications for GANC Gene

Computer assisted cloning of human neutral alpha-glucosidase C (GANC): a new paralog in the glycosyl hydrolase gene family 31.(PMID: 12370436)Hirschhorn R … Kasper JS(Proceedings of the National Academy of Sciences of the United States of America 2002)2342260