In a new fundraising e-mail from the DCCC, Speaker Nancy Pelosi sought to mobilize supporters by giving them a serious warning: That 2010 is the toughest midterm election for Democrats ever.

"The Republican defenders of the status quo are shouting because they understand that this is the toughest Midterm Election that Democrats have ever faced," Pelosi writes. "They also understand that this is a critical month for health insurance reform and they are trying to deal a serious blow to President Obama's agenda for moving America forward."

Of course, most people would say the toughest midterm cycle for Democrats in modern memory was 1994, when the Dems lost eight Senate seats and 54 House seats -- and which also followed a failed attempt to guarantee universal health care.

Check out the full e-mail after the jump.

Dear Friend,

If this summer proved anything, it showed how urgently we must stand together to restore civility to our politics and help President Obama seize this historic moment for health insurance reform in America.

You have already taken a stand against the Republicans' attempt to shout down President Obama and restore civility in Washington. For that, I cannot thank you enough.

We have entered the make-or-break month. The media is closely watching to see which side has the momentum. With the Republicans already claiming victory for trying to silence respectful debate, it is up to grassroots Democrats to show the world that no amount of shouting can drown out our determination to enact health insurance reform.

In his eloquent call for action last week before a joint session of Congress, President Obama called on us to "replace acrimony with civility." He reiterated his call to restore civility to Washington during his interview on "60 Minutes" this weekend. Yet, our opponents continue their name-calling in a cynical attempt to derail these reforms.

The Republican defenders of the status quo are shouting because they understand that this is the toughest Midterm Election that Democrats have ever faced. They also understand that this is a critical month for health insurance reform and they are trying to deal a serious blow to President Obama's agenda for moving America forward.

It is urgent that we stand together as Democrats. With all eyes on the coming Midterm Elections, let us use this critical September deadline to show the world just how prepared we are to maintain a strong Democratic Majority for President Obama so he can keep America moving in a New Direction.

Thank you.

Nancy PelosiSpeaker of the House

P.S. The Republicans recognize that September is the make-or-break month for health insurance reform. That is why they have increased their shouting and their false attacks on President Obama. It is urgent that we stand together.