Tuesday, April 27, 2010

Management of neuroendocrine tumour (NET)

Neuroendocfine tumor are a relatively rare group of tumour .The incidence and the prevalence has been increasing over the year .This probably is due to increase awareness among the medical professionals and the pathologist .The spectrum of clinical and histological grading vary widely .The prognosis varies widely depending on number of factorsageload of diseasesite of disease liver only Vs other aressymptomPerformance status (is patient active)etc

There are number of management option .So it should be ,managed with multidisciplinary team .1-surgery2-chemotherapyCisplatinetoposidestreptozocincapecitabineTemozolamaide5-FUDoxorubicin etc in combination3-Radioembolisation (blocking segment of liver with cancer with beads)4-Lutetium and other PRRT treatment - available in Europe ,part of Australia5-symptom control with somatostatin analogue (some evidence it has anti cancer effect)6- clinical trialSunitinibeverolumus

For patients being investigated for cancer unknown primary -- please check with your doctor if this might be NET

seek opinion from centres which deals with these cancer .Erasmus University Medical Center, Rotterdam (The Netherlands)Uppsala University Hospital, SwedenBad Berka Germany

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treatment of cancer with chemotherapy ,targeted therapy in a multidisciplinary team is my proffesion .I love to communicate with my patient .Sometime looking at these blogs answers my question or raises question that my patient can ask