The authors draw attention first to the contemporary attempts of the application of transcranial magnetic stimulation (TMS) in the treatment of cognitive impairment, personality disorders and sleep disturbances. Then they widely discuss available data related to the results of several years of application of TMS in the treatment of severe depressive episodes. They refer to the findings concerning changes found in these individuals and recall the basic data about so-called connectivity and default mode network (DMN). The results of these attempts of treatment allow to draw conclusions about psychopathological mechanisms of depressive syndromes and even the essence of self-consciousness. Dealing with these conclusions was the main goal of the authors. They are convinced that they should be familiar to every doctor.