Typically derogatory within a certain culture, subject, or "Matter at hand". When labeling someone as Tiddlywinks, you are primarily mentioning the aspects of their idiotic breadth of being an absolutely pussy .

Jimmy - "So what the hell is Frank doing over there? I don't know what the hell is going on.. "

Thomas - "Got absolutely no idea Jimmy, he's off in fuckin' Tiddlywink land or something, he's a fucking retard Jimmy.."

Frank - "Hey guys! Hahaha, I was playing GTAV the other day, and I put a bunch of C4's on some cop cars, hehee and they went BOOOOMM"

Whilst Frank is saying that, he's actually drooling from his mouth, making himself look like a retard and that he's off in Tiddlywinks land....