Projects within the BCCN:

In the context of the BCCN we are involved in two projects:In A1 we study changes in cellular calcium signaling based on changes on the network level. The effect on the calcium level will be investigated with respect to implications for e.g. schizophrenia or depression. This work takes place in collaboration with Hilmar Bading.In A4 we study the synapse at the neuromuscular junctions of the fruit fly as a model to investigate psychiatrically relevant genes in regulating intracellular dynamics and synaptic structure and function. The collaboration with Christoph Schuster will derive connections between genetic variations and morphologic alterations of the synaptic boutons. In a detailed computational model these morphologic specifications can be investigated with respect to synaptic signaling.