As a person going through a long bout of stressful times i have become increasingly sensitive to products i once enjoyed using. i was skeptical about this serum because i feel like what is going on is mostly psychological and believe the physical stuff will resolve when the stress does. my skin can tolerate and is mildly soothed by the pycnogenol creme by derma-e but my face was still red, painful and hot so i took a chance and ordered this. well, relief. the first few days it was slightly tingly (a not wholly unpleasant sensation) and now i have markedly different tone to my skin and most gratefully the pain and heat are diminished. i still get red but this product has been relieving and soothing. i hope they don't change the formula (especially no hyaluronic acid or witch hazel anything!)