10 things you need to know for Friday

Health and Human Services Secretary Kathleen Sebelius departs after holding a news conference at the Wesley Health Center, one of two facilities she visited where locals can get help navigating the Affordable Care Act on Thursday Oct. 24, 2013, in Phoenix, amid calls for her resignation after the rollout of insurance exchanges under the new federal health care law. (AP Photo/Ross D. Franklin)

Your daily look at late-breaking news, upcoming events and the stories that will be talked about Friday:

1. WHERE THE HEALTH CARE WEBSITE WENT WRONG. Contractors say the site’s problems trace back to insufficient testing and late changes government officials made.

2. SOME DEMOCRATS SEEK DELAY IN HEALTH CARE LAW. Six Senate Democrats propose delaying the March 31 deadline for applying for coverage and a seventh is co-authoring a bill to postpone the $95 penalty.

3. MERKEL SAYS SPYING ALLEGATIONS HAVE HARMED TIES WITH US. “We need trust among allies and partners,” the German leader says. “Such trust now has to be built anew.”

4. PORTUGUAL REOPENS THE MADELEINE MCCANN CASE. Prosecutors say new evidence has emerged more than six years after the British girl vanished.

5. WHY ACTIVISTS ARE PUSHING SAUDI WOMEN TO GET BEHIND THE WHEEL. They hope recent reforms made by the monarchy have readied the deeply conservative nation for change.

6. FDA RECOMMENDING LIMITS ON MOST-PRESCRIBED PAINKILLERS. In a big shift, the agency says hydrocodone-containing drugs should be subject to the same restrictions as other narcotics like oxycodone and morphine.

7. WHAT LAW OBAMA WANTS PASSED BY YEAR’S END. The president renews his call for Congress to approve a comprehensive immigration bill.

8. TWITTER SETS $17 TO $20 PER SHARE RANGE FOR IPO. The social networking company says it could raise as much as $1.6 billion in the offering.