Minimally-Invasive Treatment for Vesicoureteral Reflux (VUR)

During the procedure, a gel-like material called Deflux (made from two synthetic sugars, dextranomer microspheres and hyaluronic acid) is implanted to support the ureter and form a better one-way valve mechanism. A small fiberoptic cystoscope is passed through the urethra and the Deflux material is injected where the ureter meets the bladder. This is done with the child under general anesthesia.

Treatment of Grade 3 or less VUR has a success rate of approximately 75 to 80 percent. If not successful with the first injection, this treatment can be repeated. This procedure involves no incisions and is done on an outpatient basis. It requires a followup appointment with a kidney and bladder ultrasound done approximately one month post-op and a Voiding Cystourethrogram (VCUG) done three months post-op. The child should continue any prophylactic antibiotics until the VCUG confirms the the reflux has resolved.