Autosomal recessive defect in which there is total absence of apoprotein B (a component of LDL, VLDL and chylomicrons). Characteristic feature is presence of acanthocytes; later in life neurological disorders and retinitis pigmentosa develop and death is usually a consequence of cardiomyopathy.

Ataxia — For other uses, see Ataxia (disambiguation). Ataxia (from Greek α [used as a negative prefix] + τάξις [order], meaning lack of order ) is a neurological sign and symptom that consists of gross lack of coordination of muscle movements. Ataxia is a … Wikipedia

Steatorrhea — is the presence of excess fat in feces. Stools may also float due to excess gas, have an oily appearance and be foul smelling. An oily anal leakage or some level of fecal incontinence may occur. There is increased fat excretion, which can be… … Wikipedia

acanthocyte — Cell with projecting spikes; most commonly applied to erythrocytes where the condition may be caused naturally by abetalipoproteinaemia or experimentally by manipulating the lipid composition of the plasma membrane … Dictionary of molecular biology