Website directory path is different

I stumble upon a problem. When I create FTP user for my website I can use th FTP and upload file just fine. The problem is my website directory is different.

My domain directory is at /var/www/clients/client0/web5/web/index.html - but the thing is if I edit index.html or upload my file in this via FTP, no changes will be made. I can't see any differences at www.mydomain.com

My REAL index file is at /var/www/index.html - changes will be see at www.mydomain.com if I edit index.html in this directory.

Apache routes all unkown requests to the /var/www folder. A unknown request is when apache does not find the combination of ip and domain, subdomain or alias in its configuration files. So the reason for your problem must have been such a mismatch