The purpose of this study is to find out if the Glucagon Stimulation Test (GST) is a reliable alternative to the Insulin Tolerance Test (ITT) for diagnosis of Growth Hormone Deficiency (GHD) and adrenal insufficiency. In some patients the accuracy of the GST for evaluation of adrenal insufficiency is compared to the ACTH stimulation test.

GST can accurately and safely diagnose adult GHD and evaluate the integrity of the HPA axis in adult patients with hypothalamic-pituitary disorders. [ Time Frame: one year ] [ Designated as safety issue: Yes ]

To asses the GH and cortisol levels during GST in patients with adult onset hypothalamic-pituitary disease in control subjedcts matched for age, gender, BMI and estrogen status

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Please refer to this study by its ClinicalTrials.gov identifier: NCT01282164