A synthetic biology database of experimentally genetic validated logic gates. LGDB documents more than 189 genetic logic gates with experimental evidence involving 80 AND gates and 16 NOR gates in three species (Human, Escherichia coli and Bacillus clausii). SynBioLGDB provides a user-friendly interface through which conveniently to query and browse detailed information about these genetic logic gates. SynBioLGDB will enable more comprehensive understanding of the connection of genetic logic gates to execute complex cellular functions in living cells.

This work was supported by the National High Technology Research and Development Program of China (2014AA021102), the Major State Basic Research Development Program of China (2014CB910504), the National Natural Science Foundation of China (31100901, 91129710, 61170154), the Scientific Research Fund of Heilongjiang Provincial Education Department (12541426).