The owners of the Three Feathers Indian Casino have acquired the town of South Park. The citizens are being forced off their land to make way for a new super highway. Faced with saying goodbye to their friends and their way of life, the boys rally the townspeople to fight back against the rich and powerful Indians.

In the SARS outbreak of 2003, about 9% of patients with confirmed SARS infection died.The mortality rate was much higher for those over 50 years old, with mortality rates approaching 50% for this subset of patients.