Donations will be divided between the following
three beneficiaries whose research goals align directly with the
CANswer project's mission. One researcher, a top university
and the leading US cancer research hospital are working to find
ANSWERS that PREVENT cancers.

ATTENTION ALL RESEARCHERS, SCIENTISTS,
ONCOLOGISTS, ETC.

If you are looking to become part of a
scientific advisory board, please contact Stefania. We are looking
for those persons who will help guide the future of the CANswer
project and lend their expertise in the field of cancer prevention,
early detection and study of cancer causes.

Dr. Zheng
Cui

Wake Forest School of
Medicine

Amazing
research in the study of innate immunity against
cancer in mice and humans.

Why
don’t most humans get cancer despite big body mass, long lifespan
and even some intentional exposures to known carcinogens (such as
cigarette smoking)? The answer may come from a single male BALB/c
mouse that unexpectedly survived challenges of highly lethal cancer
cells in 1999. The survival of this mouse was very
surprising since no other mouse of any strain had ever survived
this type of cancer. Even more surprising was that about 40% of
offspring of this male mouse also survived many different cancer
challenges, meaning that this cancer resistance is a genetic trait.
This trait has now been passed on to more than 2000 offspring in
more than 15 generations and in several different mouse
strains.In
the last several years, intense study has revealed additional
surprises. 1) Although the inheritance pattern of this trait is
simple, the genetics is not conventional. There was no conventional
linkage found so far between the trait and a fixed location on any
chromosome, suggesting a possibility for a jumping gene or a
“paramutation”-like element. 2) The cancer resistance is entirely
mediated by the leukocytes of innate immunity that are able to sort
out cancer cells for specific killing without harming normal
cells.

“I am very excited
about these findings especially when we achieved these progresses
only with the grassroots support like yours and without government
support.” - Dr. Zheng Cui

The
cancer resistant mice are healthy and long-lived. 3) The mice can
resist a wide array of cancer cells and endogenous malignancies. 4)
Transfer of leukocytes with this high level of cancer-killing
activity (CKA) from these cancer-resistant mice cures the most
aggressive advanced cancers in other mice without any side
effect.

Center for
Cancer Prevention Research

Rutgers University Ernest Mario School of
Pharmacy

What They
Do

Stopping cancer
before it starts: Rutgers is one of the few research centers
dedicated to preventing—rather than treating—cancer, the
second-leading cause of death in the United States. The center’s
scientists conduct basic research into the causes of
cancer and identify novel strategies to prevent, delay, or treat
cancer. Their most-promising discoveries move quickly into
cancer-prevention trials, where the potential to save human lives
is real.

Who
They Are

More
than two dozen Rutgers researchers are affiliated with the center.
The core of our work draws on the pharmaceutical and biological
sciences, but we reach across Rutgers to collect the university’s
broad expertise and focus it on the problem of cancer.
Collaboration among experts in pharmaceutical sciences ·
genetics · chemistry · molecular biology · food science ·
psychology · and more—energizes our research.

We also
collaborate with many respected institutions representing health
care · industry · and academia. With our partners, the center
conducts basic research and helps to implement, monitor, and
analyze clinical trials of potential cancer-prevention strategies.
Such investigations are currently under way at the National Cancer
Institute and several other laboratories and medical
centers.

Cancer
Prevention Research Training Program

MD Anderson The University of
Texas

Mission

Their
mission is to recruit, educate, train, and launch scientists in
successful careers in cancer prevention by providing the highest
quality research training environment, mentoring relationships, and
career development opportunities, with the goal of launching each
trainee of the division toward the scientific research role of
principal investigator early in his or her career.

•
Immerse the trainee in the type of multi-disciplinary research
environment typical of cancer prevention and control, with the
endpoint objective of launching the trainee toward the scientific
research role of principal investigator relatively early in his or
her career;

•
Coordinate a curriculum of educational activities in cancer
prevention and career development training for trainees and
faculty;

•
Strengthen mentoring by providing resources, support, and guidance
to trainees and mentors;• Seek
to become nationally and internationally renowned for outstanding
training and education in cancer prevention and scholarly work in
training and education.