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Endolymphatic sac tumors are very rare tumors (adenomas) arising at the interface between the posterior fossa and the petrous temporal bone. Hemangioblastoma lesions in spinal cord and cerebellum in patient with Von Hippel Lindau disease, who also had an endolymphatic sac tumor.
Some of these tumors are associated with von Hippel Lindau disease (VHL), which is characterized by angiomatosis of the retina and cerebellum and similar lesions in other organs.
Damage is due to destruction of the ear and involvement of close by neurological structures. Radiological studies show temporal bone destruction with a tumor centered in the retrolabyrinthine petrous bone above the jugular bulb at the interface between the posterior fossa dura and petrous temporal bone.
VHL is an inherited disorder associated with cysts in the kidneys, pancreas and male genital tract. MRI scans of large tumors show hyper and hypointensity on both T1 and T2 images with strong post-gadolinium enhancement. Agressive papillary adenoma of the cerebellopontine angle: Case report of an endolymphatic sac tumor. There is also an increased risk of developing clear-cell renal cell carcinoma as well as pheochormocytoma. I often told myself, a€?Soon this mess will be over, and when it is, wea€™re headed to the next level of glory that God has for us!

Wea€™re going from glory to glory!a€?A But one day I was pondering this verse and thinking deeply about what it meant to go from glory to glory. VHL is inherited in an autosomal dominant fashion, but two copies of the mutation are needed to cause the disorder.
A second mutation can occur during a person's lifetime in a particular cell, which allows tumors and cysts to develop. It says we are going fromA glory to glory a€” in other words, from a current glorious place to another higher gloriousplace.A This clearly means that you and I wona€™t be promoted to the next realm of glory until the realm where we presently live is glorious. So if we want to go upward into a greater glory, we have to first make glorious the place where we are living and functioning right now.A When I saw this, it made me want to take a good, hard look at my life and ministry. Only after we have truthfully seen and acknowledgedA what we are can we make a sincere decision to change. A truthful recognition of the facts is part ofA the process that removes the veil from our eyes so the Lord can correct us, change us, transform us,A and prepare us to move upward into the next glorious phase for our lives. The word metamorphoo is never used in the Old Testament Septuagint, and it appears only four times in the New Testament. Paul also uses it in Romans 12:3 to tell us that we are to be transformed by the renewing of our minds. The Holy Spirit lets us know through Paul that we canA actuallyA exchange our present appearance, our current status, for one that is more glorious.
In fact, denial of the truth will just keep us stuck in the same hard place for a longer period of time.

Telling yourself that everything is allA right when it isna€™t may temporarily relieve you from the pain of having to look at the facts head-on. But the kind of change I am describing to you today is only initiated when you are willingA to get honest with yourself and with God about your behavior, your attitudes, and the condition ofA every area of your life at this present moment. If youa€™re willing to remove the veil from your eyes andA let the Holy Spirit really show you the areas where you need to be transformed, HeA will change you. However, He isna€™t bothered if HeA has to wait until you correctly finish your current task.
Show me every area in my life that needs to be changed, and helpA me give You complete liberty to transform those parts of my life. IA have asked the Holy Spirit to open my eyes and to help me see those parts of my life that needA to be transformed. What are the areas of your life that are not glorious a€” the areas you most need to work on?A 2.