City's first home game will be against the Newcastle Jets at AAMI Park on October 19.

The 2014-15 A-League campaign will open with Melbourne Victory at home against Western Sydney Wanderers at Etihad Stadium on Friday October 10 and end with the grand final on May 10, Football Federation Australia (FFA) announced on Thursday.

The draw includes Thursday night football for the first time, with four fixtures scheduled in rounds 10, 14, 22 and 25, as well as a bumper 21 games in 22 days over the summer period.

The competition will break for three weeks in January during the Asian Cup, except for three games which will be played in non-host cities.

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A-League boss Damien de Bohun said the draw was the most challenging to produce in the competition's history, given the scheduling of the Asian Cup, FFA Cup and Asian Champions League tournaments.

"But when it's all said and done, we do believe we've landed on what is a very fair and equitable draw that will really excite the growing legion of fans," he said on Thursday.

As big a boost as Villa's signing is, De Bohun said that was not taken into consideration when planning the draw or booking venues.

"That might sound strange, but the fixture is not about an individual player," he said, adding that it was unclear exactly which games he will be playing.

"We're rapt that David Villa's coming, we're rapt that marquee players are coming into the competition.

"But to create a sustainable and long-term view of the competition, it's much more than that.

"No doubt it's a great story, and there's no doubt that there's people all over Melbourne now contemplating becoming A-League members and fans because of what's happening at Melbourne City."