Is your cholesterol affecting your memory?

When cholesterol is discussed we often think about the heart, heart disease and even stroke, but memory and cognitive function don’t generally cross our minds, although they should. New research from Heidelberg University in Germany found that having high cholesterol can negatively affect memory and cognitive decline in aging.

Cholesterol is naturally produced by the body and also ingested through the foods we eat. When cholesterol levels are normal it actually helps the body function properly, but when cholesterol levels get too high, it becomes a serious threat to overall health.

When “bad” cholesterol – or LDL – becomes greater than “good” cholesterol – HDL – plaque can form in our arteries, narrowing them over time and limiting the amount of blood that can get through. Not only does this make the heart work harder, but it can ultimately lead to a clogged artery, which can have serious health consequences.

High cholesterol affects memory and cognitive function

The findings from the study suggest that for individuals who carry the ApoE4 genetic risk factor for Alzheimer’s disease, cognitive decline may be reduced by lowering cholesterol – even more so if they have cardiovascular disease.

ApoE4 is a protein that plays a role in the metabolizing of blood lipids. It transfers cholesterol to nerve cells, among other functions. There are three different variants of ApoE4 that can increase the risk of Alzheimer’s disease.

The researchers used blood samples and medical data from two alternative studies of older adults who took cognitive and memory tests. The two studies included the ESTHER study of 1,434 individuals and the KAROLA study of 366 participants. Participants with lower cholesterol performed better on cognitive and memory tests compared to those with higher cholesterol.

The findings suggest that to maintain memory and cognitive function, taking necessary measures to lower cholesterol and prevent cardiovascular disease is crucial.

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On any matter relating to your health or well-being, please check with an appropriate health professional. No statement herein is to be construed as a diagnosis, treatment, preventative, or cure for any disease, disorder or abnormal physical state. The statements herein have not been evaluated by the Foods and Drugs Administration or Health Canada. Dr. Marchione and the doctors on the Bel Marra Health Editorial Team are compensated by Bel Marra Health for their work in creating content, consulting along with formulating and endorsing products.