Left ventricular mass and end diastolic diameter are increased in aged HIV-1 transgenic mice

Figure 1. A comparison of cardiac function in both young and aged HIV-1 transgenic mice . Two-dimensional M-mode echocardiographic analyses were performed on both young (~3 months) and old (~18 months) wild-type and HIV-1 (MSB) mice. Data analyses revealed a significant increase in LV mass and LVEDD in aged HIV-1 transgenic mice as compared to aged-matched wild-type control animals. There was no difference observed in LVFS between either groups. All summary data are presented as mean ±SEM (*p<0.05) (n=≥6/group).