Celebrity endorsements aren't anything new, but that doesn't change the fact that we love this recent trend of straight-to-Youtube public service announcements that are massively overloaded in our favorite Hollywood stars. While the Stand Up To Cancer PSA doesn't feature any surprising announcements like April's celebrity-filled Give A Damn PSA did, it certainly is funny yet sincere enough to get our attention.

The whole idea behind the Stand Up To Cancer (SU2C) PSA "Change The Odds" is, as PSA's are wont to do, tell the public the odds of contracting some form of cancer. For a male, Dakota Fanning informs the audience, it is a one out of two chance. For a female, it's one in three.

This PSA is set to broadcast on September 10 during a one-hour broadcast fundraising event at 8pm EST and PST/7pm CT, and will be simulcast commercial free (except, of course, for the PSA) on ABC, CBS, NBC, FOX, HBO, Discovery Health, E!, MLB Network, The Style Network, VH1, HBO Latino, Showtime, TV One, G4 and hosted by network news anchors Katie Couric, Diane Sawyer and Brian Williams. We think it's at least fair to let Olivia Munn get some hosting skills in there, considering she participated and is one of the hosts on G4.