Uses
Folkloric
Decoction of roots used for fevers.
Infusion of the bark used as wash for the teeth and gums.
Infusion of leaves used for colds, fevers, skin ailments and purging.
Reported to be abortifacient.
Decoction of leaves used as mouth wash and gargle for mouth ulcers.
Decoction of flowers used for erysipelas and inflammation of the eyes.
Powdered flowers used as insecticide.
Fruit is astringent and used for diarrhea and dysentery.
In the Amazon, leaf juice used for fevers; the flower juice for sores.
Seeds used for cough, chest pains, breathing difficulty.
Roots used to induce first trimester abortion.
Leaves are purgative; used for renal stones, malaria, bronchitis.
In Ayurvedic medicine, used for fever, jaundice, colic, flatulence, malignant tumors.
In Nicaragua, astringent infusion of the bark is used as a wash for teeth and gums.
In the West Indies, decoction used for fevers.
In the Antilles, the leaves are used as emmenagogue and abortifacient.
In Jamaica, plant is used as a purgative.

Studies
• Antimicrobial activity of Caesalpinia pulcherrima, Euphorbia hirta and Asystasia gangeticum: Studies on the ethanolic extracts of the dry fruits of C. pulcherrima showed a broad spectrum of antimicrobial activity against E. coli (enteropathogen), Proteus vulgaris, Pseudomonas aeruginosa and Staphylococcus aureus.
• In vitro antiviral activities of Caesalpinia pulcherrima and its related flavonoids: A study showed a potential for use in the treatment of infection caused by two viruses: herpesviruses and adenoviruses.
• Anti-inflammatory activities of flavonoids isolated from Caesalpinia pulcherrima: The study supports the use of Caesalpinia pulcherrima for the treatment of inflammtory conditions in traditional medicine.
• Furanoid Diterpenes / Antibacterial / Antifungal : Study isolated four new cassane-type furanoditerpenoids from the leaves of CP. Antimicrobial testing showed activity against bacteria (S aureus, E coli, P aeruginosa and B subtilis) and fungia ( C albicans and T mentagrophytes).
• Nutrient studies of CP Seeds: Study suggests C pulcherrima could be a good source of low cost plant protein, a good source of iron and calcium; the whole seeds more nutrient-rich than the seed nuts.
• Flavonoids / Antiinflammatory: Study isolated five flavonoids from CP which significantly and dose-dependently inhibited inflammatory mediators, NO, cytokines (TNF and IL-12).
• Antifungal: Study of methanol extract of 9 Indian medicinal plants showed C pulcherrima with good antifungal activity against C albicans.