Target details

Target details

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Alternative Name

CCR10 / GPR2

Background

Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. CCR10 in particular is the receptor for the skin-associated CC chemokine CCL27 (CTACK) as well as the novel chemokine CCL28 that displays chemotactic activity for resting CD4+ and CD8+ T cells.Synonyms: 2826, 600240, GPR2, P46092, CCR10

Research Area

Chemokines, Receptors

Application Details

Application Details

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Application Notes

ELISA: Use at a dilution of 1/75000. ICC: Use at a dilution of 1/1000. IHC-P: Use at a dilution of 1/500. WB: Use at a dilution of 1/250. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.