TCTN1 Proteins by Origin and Source

More product categories related to Tectonic Family Member 1 Protein

More Proteins for Tectonic Family Member 1 (TCTN1) Interaction Partners

Human Tectonic Family Member 1 (TCTN1) interaction partners

High TCTN1 expression is associated with Pancreatic Cancer.

These findings confirmed the direct association between the TCTN1 gene and prostate cancer growth in vitro.

These data suggest TCTN1 is essential for glioma cell viability, and dysregulation of TCTN1 may play a key role in glioma tumorigenesis.

TCTN1 may serve as a novel prognostic factor and a potential therapeutic target for glioblastoma.

Mutations in Tctn1 is associated with ciliopathies.

Mouse (Murine) Tectonic Family Member 1 (TCTN1) interaction partners

Loss of Tctn1 is associated with ciliopathies.

During neural tube development, mouse Tectonic is required for formation of the most ventral cell types and for full Hedgehog (show SHH Proteins) (Hh) pathway activation. Tectonic plays an additional role in repressing Hh pathway activity.

Tectonic Family Member 1 (TCTN1) Protein Profile

Protein Summary

This gene encodes a member of the tectonic family of secreted and transmembrane proteins. The orthologous gene in mouse is required for formation of most ventral cell types. It functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene.