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Abstract

Background

Previous studies in adults have found that a lower resting metabolic rate is a predictor
of future body weight gain.

Methods

To determine if energy expenditures are reduced in infants born to obese mothers,
21 healthy infants (3.9 ± 1.9 months) born to lean (n = 7, BMI < 25 kg/m2), overweight (n = 7, BMI between 25–30) and obese (n = 7, BMI>30) mothers, respectively,
participated in this study. Measurements of infant weight, length and skin-fold thicknesses,
and mother's weight and height were obtained. Infant energy expenditure was measured
for 4-hours using the Enhanced Metabolic Testing Activity Chamber. Metabolic data
were extrapolated to 24-hours and adjusted for differences in age and body composition
using linear regression analysis (SPSS, version 13) and expressed as kcal/day. Differences
between the three groups were determined by one way ANOVA with the Bonferroni Post
Hoc test procedure (p < 0.05).

Conclusion

Lower extrapolated 24-h energy expenditure was present in infants of overweight and
obese biological mothers during the first three to six months of life. Furthermore,
these infants showed increased BMI and body fat. If these changes are unchecked future
childhood obesity may result.