Othala’s magickal and divinatory meanings include home, land, houses, permanence, possession, heritage, the past, buildings, places, security, ancestry, inheritance, tradition, things of a fixed and unchanging nature, and ownership. Steadfastness, endurance, and eternality fall under the aegis of this rune. Othala is immovable property, as a general rule.

So you can see the symbolism of a Runes reversal, yes?
loss of land,loss of heritage,loss of permanence,loss of ancestry,etc..