Since graduating from University College London medical school with Distinction, Dr. Holmes embraced academic experience at every opportunity, with successful application to the UK National Institute for Health Research (NIHR) integrated academic pathway, which enabled him to pursue research interests while practicing clinical medicine in the UK National Health Service. After four years of practicing as a general internalist, he applied to the UK Medical Research Council and was awarded a Population Health Scientist Fellowship. During this period, he worked towards a Masters in Epidemiology and a PhD in Genetic Epidemiology. He studied Epidemiology at London School of Hygiene and Tropical Medicine, graduating with Distinction and winning the class prize for his thesis. His PhD was centered in investigating public health applications of cardiovascular genomics in which he learned and practised techniques that enable understanding of causal inference, and yielded several high-impact articles that have enabled scientific progress into the determinants of cardiovascular disease.

At Penn he is working with Drs. Brendan Keating, Kim Olthoff, and Professor Abraham Shaked to set up large-scale genomics projects to investigate the genetic determinants of clinical outcomes following organ transplantation. This works aims to identify modifiable risk factors that can be targeted to improve clinical outcomes for these patients.

Faculty Appointments

2013 - present

Research Assistant Professor of Surgery, Perelman School of Medicine
University of Pennsylvania, Philadelphia, PA

2009 - 2013

Clinical Research Associate, University College London, London, United Kingdom

Hospital and Administrative Appointments

2005 - 2009

NHS Academic Foundation and Academic Clinical Fellow Appointments

Education/Training

2009-2013

PhD - Genetic Epidemiology Group, Department of Epidemiology & Public Health
University College London

BSc - University of St. Andrews, London
Medical Science (honours with 1st class)

Postgraduate Training and Fellowship Appointments

2009 - present

Medical Research Council Population Health Scientist Fellowship G0802432,
Genetic Epidemiology Research Group, Department of Epidemiology and Public Health,
Faculty of Population Health Sciences, University College London, London, UK