Re: ? for Saint J: dexe vs Adderall <

> > S.J. wrote:> > I also question the use of L-amphetamine, as it has negative side effects. Another "least patentable difference" ?> > > > James here...> > Adderal was on the market as Orbitol till the 70's, was pulled because of abuse. Was re-introduced as Adderal as of late.^^^^^^Obetrol was not pulled because of "abuse" exclusively. It was discontinued because the AMA re-evaluated the use of amphetamine for longterm obesity therapy. At the same time, the AMA discontinued the use of all amphetamine/barbiturate mixtures, calling themirrational; e.g., Obedrine, Eskatrol, Biphetamine-T, all of which were called "goof balls."

> > //snip//>

>D is "left handed" arrangement, L is the right. Biology mostly runs on D isomers, the universe is rather left handed, though there are exceptions, like the aminos. Look on the net about isomers, you really need graphics to understand this ! Many times the L is not active in humans, or is not useful, or has negative side effects.^^^^^^^^^Pardon me, but you have these terms mixed up. The "D" refers to "dextro" or RIGHT HAND ROTATION of the molecules.The "L" (levo) is the left hand rotation.The "dextro," "d-," is always the more powerful of the two.Both "d-" and "l-" are latin terms.

An example of L-amphetamine is benzedrine, or "Bennies," a truck-driver's friend (good movie: DEATH IN SMALL DOSES).Benzedrine was also stuck in an inhaler called BENZEDREX to dry up mucous tissue in the nose.

An example of d-amphetamine is dexedrine, or "Dexies," a delightful "house-wife" drug which can lead to the Mad-Hatters Syndrome, if abused (and it usually is).

Another difference between the two is the way the almighty DEA "sees" them.Dexedrine is classified as a CONTROL II substance, whereas benzedrine, asa rule, is considered a CONTROL III drug (DIDREX, an anoretic from UpJohn).

I suppose you could mix the two, but that would send the DEA into a tizzy.ADDERALL, from what I understand, contains amphetamine resins, whatever that crap is.

> Dex is all d-amphetamine, proven to be active in humans. > L-amphetamine has some action, but tends to have more negative effects. Reported are: makes you more shakey, dysphoria, sweaty, ect.^^^^^^^^^See DIDREX reference above.

> The D vers is more smooth feeling.^^^^^^^^^^^^^^Meaning what?

> "Least patentable difference" is the least chemical difference you can change a compound from the patent to get another patent. In this case it is the addition of L-amphetamine, and a few other things. ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^This makes no sense at all, sorry.

> j

The point of all this: when choosing between Ritalin and Dexedrine, go with the one that's been around since 1927; i.e., tried and true d-amphetamine.Of course, you might want to ask your pdoc for DESOXYN (methamphetamine - Abbott) providing, of course, he doesn't laugh youright out of his office.