study demonstrated a cancer-specific role for AROS in the regulation of survival in a panel of human cell lines; data suggest that AROS, as well as SIRT1 (show SIRT1 Antibodies), promotes survival in cancer cells while being redundant for viability in non-cancer cells

This study analyses Sirt1 (show SIRT1 Antibodies) modulation by several putative Sirt1 (show SIRT1 Antibodies) regulators, showing that the regulator protein AROS has an unusual conformation and that the Sirt1 (show SIRT1 Antibodies) catalytic domain is sufficient for modulation by resveratrol.

identified a novel protein, which was named S19 binding protein (S19BP). No known functional motifs were found in S19BP except a short polylysine tract embedded in a putative nucleolar localization signal.