Since 1992, Blitt has created illustrations and drawn more than 80 covers for The New Yorker, including "Deluged," which in 2006 was voted Cover of the Year by the American Society of Magazine Editors, and "The Politics of Fear," a finalist for the same award in 2009. His work has also appeared in Vanity Fair, Time, Rolling Stone, and The Atlantic. From 2003-2011, he illustrated Frank Rich's column in The New York Times.

Blitt has been honored with exhibitions and awards from the Society of Illustrators, Print, and American Illustration, and is a member of the Art Directors Club Hall of Fame. He has also illustrated numerous children's books, notably Once Upon a Time, the End (Asleep in 60 Seconds) and George Washington's Birthday: A Mostly True Tall Tale. He lives and works in Roxbury, Connecticut.

Blitt's presentation, called "In One Eye and Out the Other," starts at 5:30 p.m. in Room 101 of the F. Ross Jones Building, Mattin Center, on the Homewood campus at 3400 N. Charles St. The event is free and open to the public.