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How tumor-causing cells are recruited in cancers linked to chronic inflammationChronic inflammation is directly associated with several types of cancer, yet the reasons as to why this happens at a cellular level remain unclear. Now, an international team of scientists led by researchers at The Wistar Institute has identified a multistep process showing not only how these cancers develop but also potentially discovering new therapeutic targets that could halt the formation and progression of tumor cells.http://medicalxpress.com/news/2015-02-tumor-causing-cells-cancers-linked-chronic.html
Inflammatory disordersMon, 09 Feb 2015 12:39:36 EDTnews342707932Enterotrack commercializing device for non-invasive inflammation monitoringEnteroTrack, LLC and the University of Colorado (CU) have executed an exclusive license agreement that will allow the company to develop and market a novel device to monitor inflammation of the gastrointestinal tract.http://medicalxpress.com/news/2015-01-enterotrack-commercializing-device-non-invasive-inflammation.html
Inflammatory disordersTue, 06 Jan 2015 16:36:57 EDTnews339784610Researchers stop 'vicious cycle of inflammation' that leads to tumor growthA team of researchers from the University of Alberta has discovered a new approach to fighting breast and thyroid cancers by targeting an enzyme they say is the culprit for the "vicious cycle" of tumour growth, spread and resistance to treatment.http://medicalxpress.com/news/2014-11-vicious-inflammation-tumor-growth.html
CancerMon, 24 Nov 2014 15:34:53 EDTnews336065684TNF inhibitors may increase cancer risk in the eyeOne of the family of drugs prescribed for rheumatoid arthritis and other inflammatory conditions is called TNF inhibitors. They act by dampening part of the immune system called tumor necrosis factor (TNF). In one of the balancing acts of medicine, the anti-inflammatory action of the drug also increases the risk for other conditions, in this case, a rare form of eye cancer, uveal melanoma. Mayo Clinic researchers make the case and alert physicians in an article in Mayo Clinic Proceedings.http://medicalxpress.com/news/2014-11-tnf-inhibitors-cancer-eye.html
Arthritis & RheumatismMon, 17 Nov 2014 11:43:03 EDTnews335446974MicroRNA molecules serve as on/off switches for inflammationUniversity of Utah scientists have identified two microRNA molecules that control chronic inflammation, a discovery that one day may help researchers prevent certain fatal or debilitating conditions before they start.http://medicalxpress.com/news/2014-10-microrna-molecules-onoff-inflammation.html
Medical researchThu, 16 Oct 2014 12:00:01 EDTnews332670501Spaghetti for celiac patients? Just add wormsAustralian researchers have achieved groundbreaking results in a clinical trial using hookworms to reduce the symptoms of celiac disease.http://medicalxpress.com/news/2014-09-spaghetti-celiac-patients-worms.html
ImmunologyThu, 25 Sep 2014 09:29:01 EDTnews330856133Why inflammation leads to a leaky blood-brain barrier: MicroRNA-155Until now, scientists have not known exactly how inflammation weakens the Blood-Brain Barrier, allowing toxins and other molecules access to the brain. A new research report appearing in the June 2014 issue of The FASEB Journal solves this mystery by showing that a molecule, called "microRNA-155," is responsible for cleaving epithelial cells to create microscopic gaps that let material through. Not only does this discovery help explain the molecular underpinnings of diseases like multiple sclerosis, but it also opens an entirely new avenue for developing therapies that can help penetrate the Blood-Brain Barrier to deliver lifesaving drugs.http://medicalxpress.com/news/2014-06-inflammation-leaky-blood-brain-barrier-microrna-.html
Inflammatory disordersMon, 02 Jun 2014 11:22:50 EDTnews320926954New treatment proposed to prevent intestinal inflammation in cancer patientsExperimental work pointing to a therapy for alleviating mucositis—a common, severe side effect of chemotherapy and irradiation of cancer patients or patients prepared for bone marrow transplantation – has been achieved by an international team of researchers from the US and Israel headed by scientists at the Hebrew University of Jerusalem.http://medicalxpress.com/news/2014-02-treatment-intestinal-inflammation-cancer-patients.html
Medical researchTue, 18 Feb 2014 13:59:18 EDTnews311954348Inflammation in prostate may reduce cancer riskDoctors at the North Shore-LIJ Health System have discovered that increased inflammation in the prostate may predict reduced risk for prostate cancer. The findings are published online in Cancer.http://medicalxpress.com/news/2013-12-inflammation-prostate-cancer.html
CancerMon, 09 Dec 2013 09:39:48 EDTnews305804376Rheumatoid arthritis and heart disease: Studies shed light on dangerous connectionPeople with rheumatoid arthritis and other chronic inflammatory conditions are at higher risk of heart disease. Who is in the most danger, why and how best to prevent and detect cardiovascular complications are important questions for physicians and researchers. Mayo Clinic studies presented at the American College of Rheumatology annual meeting shed new light on this connection, in part by revealing factors that seem to put some rheumatoid arthritis patients in greater jeopardy of heart problems: early menopause, more severe rheumatoid arthritis and immunity to a common virus, cytomegalovirus, among others.http://medicalxpress.com/news/2013-10-rheumatoid-arthritis-heart-disease-dangerous.html
Arthritis & RheumatismSat, 26 Oct 2013 16:30:01 EDTnews302019444Genetic makeup and diet interact with the microbiome to impact healthA Mayo Clinic researcher, along with his collaborators, has shown that an individual's genomic makeup and diet interact to determine which microbes exist and how they act in the host intestine. The study was modeled in germ-free knockout mice to mimic a genetic condition that affects 1 in 5 humans and increases the risk for digestive diseases. The findings appear in the Proceedings of the National Academy of Sciences.http://medicalxpress.com/news/2013-09-genetic-makeup-diet-interact-microbiome.html
Medical researchWed, 25 Sep 2013 12:32:42 EDTnews299331149Children with behavioral problems more at risk of inflammationChildren with behavioral problems may be at risk of many chronic diseases in adulthood including heart disease, obesity, diabetes, as well as inflammatory illnesses (conditions which are caused by cell damage).http://medicalxpress.com/news/2013-09-children-behavioral-problems-inflammation.html
Psychology & PsychiatryThu, 05 Sep 2013 08:53:56 EDTnews297590020Fish oil found to help serious pregnancy complicationsTaking fish oil during pregnancy could limit the effects of serious complications such as gestational diabetes, pre-eclampsia and miscarriage as well as enhancing fetal growth, according to researchers at The University of Western Australia.http://medicalxpress.com/news/2013-07-fish-oil-pregnancy-complications.html
HealthMon, 29 Jul 2013 07:30:02 EDTnews294301009DNA particles in the blood may help speed detection of coronary artery diseaseDNA fragments in your blood may someday help doctors quickly learn if chest pain means you have narrowed heart arteries, according to a new study published in the American Heart Association journal Arteriosclerosis, Thrombosis, and Vascular Biology.http://medicalxpress.com/news/2013-07-dna-particles-blood-coronary-artery.html
CardiologyMon, 01 Jul 2013 10:33:23 EDTnews291893593Study finds dramatic increase in hospitalization of US children with inflammatory bowel diseaseThe largest investigation to date has found a dramatic increase in the number of hospitalizations for children with inflammatory bowel disease (IBD) during the past decade in the United States.http://medicalxpress.com/news/2013-06-hospitalization-children-inflammatory-bowel-disease.html
Inflammatory disordersTue, 25 Jun 2013 12:46:11 EDTnews291383162Simple prognostic tool for GPs could more accurately predict disease outcomes in musculoskeletal conditionsGPs could more accurately predict the likely progression of disease in patients with musculoskeletal conditions by asking them a simple set of generic questions during their very first consultation, new research funded by Arthritis Research UK has shown.http://medicalxpress.com/news/2013-06-simple-prognostic-tool-gps-accurately.html
HealthWed, 12 Jun 2013 08:52:54 EDTnews290245960Statin therapy may reduce risk of osteoarthritis(Medical Xpress)—Regular use of cholesterol-lowering medicines calledstatins may reduce a person's chances of developing the degenerative joint disease osteoarthritis, UK scientists have found.http://medicalxpress.com/news/2013-05-statin-therapy-osteoarthritis.html
Arthritis & RheumatismThu, 30 May 2013 06:22:17 EDTnews289113726Biomarkers discovered for inflammatory bowel diseaseUsing the Department of Defense Serum Repository (DoDSR), University of Cincinnati (UC) researchers have identified a number of biomarkers for inflammatory bowel disease (IBD), which could help with earlier diagnosis and intervention in those who have not yet shown symptoms.http://medicalxpress.com/news/2013-05-biomarkers-inflammatory-bowel-disease.html
Diseases, Conditions, SyndromesTue, 21 May 2013 17:21:31 EDTnews288375680Foul-smelling gas shows health benefits in reducing joint swellingA gas associated with the smell of rotten eggs has proven to effectively reduce joint swelling, in research which could lead to advances in the treatment of arthritis.http://medicalxpress.com/news/2013-04-foul-smelling-gas-health-benefits-joint.html
Arthritis & RheumatismMon, 29 Apr 2013 12:51:29 EDTnews286458682People with depression may not reap full benefits of healthy behaviorsDepression may inhibit the anti-inflammatory effects typically associated with physical activity and light-to-moderate alcohol consumption, according to researchers at Duke Medicine.http://medicalxpress.com/news/2013-03-people-depression-reap-full-benefits.html
Psychology & PsychiatryTue, 26 Mar 2013 12:29:47 EDTnews283519780Study shows that blocking an inflammation pathway prevents cardiac fibrosis(Medical Xpress)—New research from UC Davis published in the Proceedings of the National Academy of Sciences shows that blocking an enzyme that promotes inflammation can prevent the tissue damage following a heart attack that often leads to heart failure.http://medicalxpress.com/news/2013-03-blocking-inflammation-pathway-cardiac-fibrosis.html
Medical researchFri, 22 Mar 2013 11:10:05 EDTnews283167535Mouse models fail to reproduce inflammatory genomic response to serious injuriesExisting mouse models do not appear to accurately reproduce the human genomic response to serious traumatic injury, including major burns, according to an article appearing in PNAS Early Edition.http://medicalxpress.com/news/2013-02-mouse-inflammatory-genomic-response-injuries.html
Inflammatory disordersMon, 11 Feb 2013 15:00:01 EDTnews279804831Potential new treatment for gastrointestinal cancers discovered(Medical Xpress)—Researchers have identified a complex of proteins that promotes the growth of some types of colon and gastric cancers, and shown that medications that block the function of this complex have the potential to be developed into a new treatment for these diseases.http://medicalxpress.com/news/2013-01-potential-treatment-gastrointestinal-cancers.html
CancerThu, 17 Jan 2013 06:14:19 EDTnews277625649Mindfulness meditation may relieve chronic inflammationPeople suffering from chronic inflammatory conditions, such as rheumatoid arthritis, inflammatory bowel disease and asthma—in which psychological stress plays a major role—may benefit from mindfulness meditation techniques, according to a study by University of Wisconsin-Madison neuroscientists with the Center for Investigating Healthy Minds at the Waisman Center.http://medicalxpress.com/news/2013-01-mindfulness-meditation-relieve-chronic-inflammation.html
ImmunologyWed, 16 Jan 2013 16:47:59 EDTnews277577269Revolutionary treatment for psoriasisThree per cent of the world's population suffer from the skin condition known as psoriasis. A Norwegian research-based company is close to developing a treatment that could help millions. The research may also prove beneficial in the treatment of other illnesses.http://medicalxpress.com/news/2013-01-revolutionary-treatment-psoriasis.html
Diseases, Conditions, SyndromesFri, 11 Jan 2013 14:45:04 EDTnews277137898New study investigates fate and function of cells transplanted to the CNSWhen different types of cells are transplanted with the intent of having them aid in repairing central nervous system (CNS) trauma, what is the fate and function of those cells? A Belgian research team carried out research aimed at answering this question by determining how five varieties of cells - neural stem cells, mouse embryonic fibroblasts, dendritic cells, bone marrow mononuclear cells (BMMNCs) and splenocytes - functioned and survived after transplantation in the CNS.http://medicalxpress.com/news/2012-12-fate-function-cells-transplanted-cns.html
Medical researchThu, 20 Dec 2012 17:19:57 EDTnews275246338Researchers work to improve efficacy of blood transfusions for preterm babies(Medical Xpress)—Results of new research from the University of Adelaide are a promising step forward in helping to improve the quality of life-saving blood transfusions for preterm babies, by reducing the likelihood of adverse inflammatory responses to the blood.http://medicalxpress.com/news/2012-11-efficacy-blood-transfusions-preterm-babies.html
PediatricsThu, 22 Nov 2012 08:40:03 EDTnews272795237Spice allergy: Sugar and spice and everything not so niceImagine a world where you could never dine away from home, wear makeup, smell of sweet perfumes or eat a large percentage of food on store shelves. According to allergists at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting that is kicking off today in Anaheim, Calif., that is the world for 2 to 3 percent of individuals living with a spice allergy.http://medicalxpress.com/news/2012-11-spice-allergy-sugar-nice.html
ImmunologyThu, 08 Nov 2012 03:00:21 EDTnews271566003Research sheds light on important role of autophagy, or self-eating cells, in developing new anti-inflammatory therapiesResearch just carried out in the Immunology Research Centre, led by Dr James Harris, based in the School of Biochemistry and Immunology, Trinity College Dublin, shows that the process of autophagy regulates the production of inflammatory molecules and may therefore represent an effective target for the development of new anti-inflammatory therapeutics. The findings have been recently published online in the Journal of Immunology.http://medicalxpress.com/news/2012-10-important-role-autophagy-self-eating-cells.html
Medical researchWed, 24 Oct 2012 10:00:01 EDTnews270286150Specific bacterial species may initiate, maintain Crohn'sPatients newly diagnosed with pediatric Crohn's disease had significantly different levels of certain types of bacteria in their intestinal tracts than age-matched controls, according to a paper in the October Journal of Clinical Microbiology. The work may ultimately lead to treatment involving manipulation of the intestinal bacteria.http://medicalxpress.com/news/2012-10-specific-bacterial-species-crohn.html
Diseases, Conditions, SyndromesMon, 22 Oct 2012 14:32:13 EDTnews270135115