The dosage and administration of Lindacals should be adjusted according to the need of the patient.

The initial dosage is:

Adults: 1-2 capsules / day

Elderly patients: 1 capsule /day

The exact dosage in osteoporosis is not defined, however the various clinical studies have used the
dosage of alfacalcidol in range of 0.5 – 1 mcg/day with or without calcium in treatment of osteoporosis.

Not recommended in children.

Subsequent dose titration can be done according to the clinical and biochemical response so as to
avoid hypercalcaemia.

Most adults respond to doses of 1 to 3 mcg/day of alfacalcidol and 0.25 – 3 gm of calcium carbonate.

Indices of response, in addition to a rise in plasma calcium, may include a progressive reduction in alkaline phosphatase, a reduction in parathyroid hormone levels, an increase in urinary calcium excretion in patients with normal renal function, bone radiography and histological improvements.