Colloquium

Deciphering The Stochastic Kinetics Of Gene Regulation

Colloquium
Deciphering The Stochastic Kinetics Of Gene Regulation

Ido Golding
Baylor College of Medicine and the Center for Theoretical Biological Physics, Rice University

Jan 26, 2018 at 2:30pm in WMC3260

Synopsis

Gene activity is the prime mover in the living cell, driving a cell’s function at any given time. I will report on recent advances in our ability to describe the stochastic kinetics of gene regulation, achieved through the combination of single-molecule fluorescence microscopy in individual cells, novel image analysis algorithms, and theoretical modeling. We apply our approach to explore gene regulation in a number of organisms representing a gradation of complexity: E. coli bacteria, fly embryos, and mouse embryonic stem cells.