The third phase of wound healing is granulation phase, which takes place to repair the damaged cells by regenerating new cells. This phase consists of different subphases, which can last up to 4 weeks in the clean and uncontaminated wound. These sub phases do not happen in discrete time frames but constitute an overall and ongoing process. The sub phases are "fibroplasia, matrix deposition, angiogenesis and re-epithelialization" (Cho & Lo, 1998). The first sub phase of granulation process is fibroplasia. In days 5-7, fibroblasts have migrated into the wound, laying down new collagen of the subtypes I and III. In normal wound healing, early type III collagen predominates but is later replaced by type I collagen. Tropocollagen, which is the precursor of all collagen types, is then transformed within the cell's rough endoplasmic reticulum, where proline and lysine are hydroxylated. After tropocollagen transformation, disulfide bonds are established, allowing 3 tropocollagen strands to form a triple left-handed triple helix, termed procollagen. As the procollagen is secreted into the extracellular space, peptidases in the cell wall cleave terminal peptide chains, creating true collagen fibrils, which mark the hallmark of fibroplasia. After fibroplasia, matrix deposition takes place. In matrix deposition, the wound is first suffused with GAGs and fibronectin produced by fibroblasts. These GAGs include heparan sulfate, hyaluronic acid, chondroitin sulfate, keratan sulfate, and proteoglycans. Then, proteoglycans bond covalently to a protein core and this contributes to matrix deposition. Later, angiogenesis takes place. Angiogenesis is the product of parent vessel offshoots which is known as new vasculature. The formation of new vasculature requires extracellular matrix and basement membrane degradation followed by migration, mitosis, and maturation of endothelial cells. Basic FGF and vascular endothelial growth factor are also involved in the modulating...

...Outline for Class Project Topic: The Skin: from growth to the healing process
1. Growth A. How the skin grows a. Layers of the skin 2. Types of skin diseases A. All different types of disesase that can be caught a. how they are caught and transmitted 3. Infections of the skin A. Types of infections a. How they can affect the body 4. How skin Heals A. What types of injuries cause the skin to go into healing mode. a. How long can a healing process take
The Skin: From growth to the Healing Process
In this paper I am going to discuss many different topics related to our skin. When discussing the skin. a good place to start is the different layers of the skin. The skin has three different layers: the epidermis, the dermis and the subcutaneous tissue(Brannon 2007) . These three layers play a very important role in how our skin grows and how it heals after injury. The epidermis is the outer layer of skin. The thickness of the epidermis varies in different types of skin. It is the thinnest on the eyelids at . 05 mm and the thickest on the palms and soles at 1.5 mm(Brannon 2007). There are five different layers to the epidermis. The bottom layers, which are shaped like columns, divide and push already formed cells into higher layers of the epidermis(Brannon 2007). Once the cells reach the top layer, which is made up of dead cells, our body sheds the top layer (Brannon 2007). This process happens approximately every...

...4 Stages of Healing
How Do Wounds Heal?
Research work on acute wounds in an animal model shows that wounds heal in four phases. It is believed that chronic wounds must also go through the same basic phases. Some authors combine the first two phases.
The phases of woundhealing are:
* Hemostasis
* Inflammation
* Proliferation or Granulation
* Remodeling or Maturation
Hemostasis:
Once the source of damage to a house has been removed and before work can start, utility workers must come in and cap damaged gas or water lines. So too in woundhealing damaged blood vessels must be sealed. In woundhealing the platelet is the cell which acts as the utility worker sealing off the damaged blood vessels. The blood vessels themselves constrict in response to injury but this spasm ultimately relaxes. The platelets secrete vasoconstrictive substances to aid in this process but their prime role is to form a stable clot sealing the damaged vessel. Under the influence of ADP (adenosine diphosphate) leaking from damaged tissues the platelets aggregate and adhere to the exposed collagen. They also secrete factors which interact with and stimulate the intrinsic clotting cascade through the production of thrombin, which in turn initiates the formation of fibrin from fibrinogen. The fibrin mesh strengthens the...

...Advanced Target Marketing
Citrus Memorial Wound Care facility provides comprehensive healing of chronic and acute non-healingwounds and offers hyperbaric oxygen therapy in an outpatient setting. The center utilizes a multidisciplinary approach to wound care. A team approach is used to provide patients with the most optimal wound treatment possible. The clinic optimizes its ability to provide patients with the best care possible by using advanced woundhealing products including bioengineered skin products, total contact casting, and comprehensive compression wraps. The wound care center offers complete coordination of care including scheduling appointment for patients that require services that are provided outside of the clinic.
Budget constraints on the marketing department has created a great need for market segmentation. Treating the surrounding population as a homogenous group is not cost effective or efficient. There is many benefits that can be obtained from a more selective target marketing approach than what is already currently used. Therefore Citrus Memorial Wound Care has recently adopted an new marketing outreach program that will be discussed in greater detail later in this summary.
Lifestyle Profile Importance
Costumer needs and preferences differ based on their lifestyles. It is important to research and...

...﻿
A Critical Review of Healing the Wounds of Sexual Addiction
Pamela D. McKoy
Liberty University
Abstract
This critical review will attempt to summarize the book “Healing theWounds of Sexual Addiction” written by, Dr. Mark R. Laaser. Highlighting all the central themes and giving an in-depth analysis of Dr. Laaser’s work on the subject of sexual addiction. It will give his perspective and evidence to support it from the book and other sources. In this review you will find that Dr. Laaser has added valuable insight to the subject on a personal level. It will also show how Dr. Laaser’s faith comes into play, being that the book is written from a Christian point of view using a Biblical worldview. This review will show that the book can and should be used by lay and professionals alike when dealing with those who suffer from the pain and sin of sexual addiction.
Keywords: sexual addiction, worldview
Summary
Dr. Mark Lasser’s book “Healing the Wounds of Sexual Addiction” gives hope for those who are in the throes of sexual addiction and those...

...nutrition on woundhealing in older people: a case study” is to educate the reader about how an elderly person’s nutritional status effects the process of woundhealing. It discusses the normal healing process, factors that may affect healing, and how to treat or prevent those factors. Many factors to contribute to the possibility of malnutrition in older adults and combined with their decline in physical activity, healing issues occur. Maintaining skin integrity is of upmost importance in the elderly to prevent pressure ulcers and other skin issues from arising. Different nutrients have specific functions that aide in the healing process.
Woundhealing is a complex process that requires good nutrition for it to happen properly. There are four different stages of woundhealing, starting with the acute inflammation phase. The inflammatory response is a reaction to tissue damage and bacterial invasion into the skin. Free radicals are released during this phase, and vitamin C, an antioxidant, is required to neutralize them. Vitamin C also helps white blood cells get to the wound to help build resistance to the infection. The second phase, reconstruction, requires neutrophils and macrophages to clear the wound of unwanted material. Fibroblasts synthesize collagen to facilitate the...

...all about a Break and the Power of Healing
What is a Wound?
A wound may be described in many ways; by its aetiology, anatomical location, by whether it is acute or chronic1, by the method of closure, by its presenting symptoms or indeed by the appearance of the predominant tissue types in the wound bed. All definitions serve a critical purpose in the assessment and appropriate management of the wound through to symptom resolution or, if viable, healing.
A wound by true definition is a breakdown in the protective function of the skin; the loss of continuity of epithelium, with or without loss of underlying connective tissue (i.e. muscle, bone, nerves) following injury to the skin or underlying tissues/ organs caused by surgery, a blow, a cut, chemicals, heat/ cold, friction/ shear force, pressure or as a result of disease, such as leg ulcers or carcinomas.
Wounds heal by primary intention or secondary intention depending upon whether the wound may be closed with sutures or left to repair, whereby damaged tissue is restored by the formation of connective tissue and re-growth of epithelium.
Wound Classification
Wounds may be classified by several methods; their aetiology, location, type of injury or presenting symptoms, wound depth and tissue loss or clinical appearance of the wound....

.... Introduction
A. Background of the Study
One of the more common occurrences in our daily life is sustaining wounds ranging from mild abrasions to deep lacerations. Wounds that are left untreated can result to infections and other complications, so proper remediation must be done immediately.
For the past several years, there has been a lot of advancement in the field of medicine. The discovery of new drugs has played a big role in the improvement of our health care. But due to the prohibitive cost of these drugs, people tend to use herbs as an alternative.
Studies have shown that some plants are as effective as the drugs found in the drugstores. There are plants found in the Philippines that have different uses such as in the treatment of diseases and illnesses. Examples of these plants are guava, lagundi and oregano. Boiled guava leaves are used as a disinfectant to treat wounds, lagundi leaves are used to treat cough and the decoction of the oregano leaves are used to cure stomach aches and degenerative arthritis. Their healing and medicinal properties can serve as an alternative to pharmaceutical drugs which could be expensive. These medicinal plants came from natural sources, making them even more beneficial because of their cost-effectiveness.
Pandakaki-puti is a shrub with elongated leaves and white flowers. Its leaves can be used as an analgesic, anti-inflammatory, and treatment for hypotention....