First time drop in CD4 after taking Atripla

May 24, 2013

I have been on Atripla since January of 2010 for HIV infection. The month of May 2013 I went for my tri-monthly lab work and the results showed that my CD4 dropped from the previous 346 to 318, though my VL is still undetectable. This raised a concern for me as this is the first time my CD4 has dropped any since being on Atripla. Could this be a sign that my infection is growing resistance and that I may need a change in medication? My doctor's note says that no changes are needed for now, however, I'm still alarmed and worried about this. any information will be greatly appreciated.

Response from Dr. Holodniy

I agree with your doctor. Another number you need to know if your CD4%, which is usually a more stable number over time. I suspect that your CD4% has not changed significantly.

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