The personal blog of Dave Fernig, thoughts on science and unrelated matters

SimpleDSFviewer

Today we published a preprint at PeerJ that describes a program Changye Sun wrote to analyse and view differential scanning fluorimetry data. This is a brilliant technique for studying interactions of small and no so small molecules with proteins. We focus on protein-polysacchairde interactions, but it works equally well in numerous other settings, including screening for enzyme inhibitors.

The code and compiled versions of the program are on GitHub – there is a link in the preprint. The preprint also provides exemplar raw data, which are used in worked examples and a user manual.