GASTROINTESTINAL HAEMORRHAGE and Concerta

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GASTROINTESTINAL HAEMORRHAGE Symptoms and Causes

Your digestive or gastrointestinal (GI) tract includes the esophagus, stomach, small intestine, large intestine or colon, rectum, and anus. Bleeding can come from any of these areas. The amount of bleeding can be so small that only a lab test can find it.

Signs of bleeding in the digestive tract depend where it is and how much bleeding there is.

Signs of bleeding in the upper digestive tract include

Bright red blood in vomit

Vomit that looks like coffee grounds

Black or tarry stool

Dark blood mixed with stool

Signs of bleeding in the lower digestive tract include

Black or tarry stool

Dark blood mixed with stool

Stool mixed or coated with bright red blood

GI bleeding is not a disease, but a symptom of a disease. There are many possible causes of GI bleeding, including hemorrhoids, peptic ulcers, tears or inflammation in the esophagus, diverticulosis and diverticulitis, ulcerative colitis and Crohn's disease, colonic polyps, or cancer in the colon, stomach or esophagus.

The test used most often to look for the cause of GI bleeding is called endoscopy. It uses a flexible instrument inserted through the mouth or rectum to view the inside of the GI tract. A type of endoscopy called colonoscopy looks at the large intestine.

GASTROINTESTINAL HAEMORRHAGE Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.

Experimental pain intensity measured on a visual analogue scale (0-100); effect of Ritalin on auditory sensitivity, measured by the response to different auditory stimulations; pain intensity (NPS 0-100) in response to thermal stimuli and the measures of the auditory tests.

Relationship between tonic dopamine release (measured by displacement of [11C]-raclopride by oral methylphenidate) and change in processing speed between baseline and after methylphenidate treatment.; Relationship between D2/D3 receptor availability in ventral striatum and prefrontal cortex and neuropsychologic deficits.; Relationship between tonic dopamine release in the ventral striatum and prefrontal cortex with neuropsychologic deficits after TBI.; Relationship between D2/D3 receptor availability and functional connectivity of the prefrontal cortex with nodes of the default mode network.; Relationship between TMS-induced short-interval cortical inhibition of M1 and tonic dopamine release.; Test motivation and reward on and off methylphenidate in TBI patients.

Frequency of binge episodes/days, as assessed by prospective daily binge diary; Frequency of objective binge episodes and overall illness severity, as assessed by both the Eating Disorder Examination Interview and Questionnaire; Clinician impression of illness severity and improvement, as assessed by the Clinical Global Impression scale; Quality of life, as assessed by the Quality of Life Inventory; Associated features of binge eating as captured by the Dutch Eating Behavior Questionnaire and Binge Eating Scale; Body Mass Index

If you think you may have a medical emergency, call your doctor or 911 immediately.

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