Trey Burton blocked a punt on the 49ers' first possession, and teammate Brad Smith recovered, giving the Eagles an early lead.

In the second quarter, Jenkins took his interception back for a touchdown before Darren Sproles returned a punt for a touchdown as the Eagles found ways to compensate for a punchless offense that was limited to five first downs and just 87 yards.

All of this came after a night of interrupted sleep, thanks to a series of false fire alarms that went off at their team hotel early Sunday morning.