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The world-wide spread of antibiotic-resistant microorganisms can be viewed as an ecological consequence of the systematic use of antimicrobial agents. Resistant bacteria prevail in healthcare environments where antibiotic selective pressure is intensive.

"Advances in nanoparticulate carriers: applications in diseases and infections"October 19-22, 2015, organized by Dr. R. Gref, CNRS at the Institute Pasteur, Paris, France has been a truly exciting 3-day International Symposium.

Announcements

February 12, 2018

Full partner Prof. A. Douhal , Femtochemistry and Microscopy group, Universidad de Castilla-La Mancha (UCLM) , Spain, was awarded the Elsevier Lectureship Award of the Japanese Photochemistry Association for the year 2018.

The drug-resistant bacteria that pose the greatest health threats: Read the article and see the "Threat list" inNature/News of this week. The article describes "The list that ranks 12 bacteria or bacterial families is topped by carbapenem-resistant Acinetobacter baumannii...Antibiotic resistance kills an estimated 700,000 people each year worldwide, and some experts predict that number to reach 10 million by 2050 if efforts are not made to curtail resistance or develop new antibiotics".

March 2, 2017

UPCOMING CycloN Hit EVENT

Workshop: "Optical microscopy in life science - from basics to state of the art".May 3-4, Gothenburgh, Sweden. Details to be announced soon.

"The EuroCD 2017 will provide an opportunity for scientists working in cyclodextrin research to meet and discuss recent advances in this field. We aim to provide a positive environment for PhD students, early career scientists and senior researchers to create and strengthen their work collaborations".Chair, Organizing Committee: prof. Helena Cabral Marques, U. of Lisbon.​

February 10, 2017

The January issue of CyclodextrinNewsdeals with the role of cyclodextrins in quorum sensing (QS), a mechanism that makes possible for a population of bacteria to behave as a multi-cellular organism in host colonization. The article is written by Dr. Eva Fenyvesi, Cyclolab SA.

December 4, 2016

The latest issue of Cyclodextrin News reviews the recent research literature on the role of Cyclodextrins in autophagy, in an article written by Dr. Eva Fenyvesi (partner CycloLab). The article includes a review on the effects of Cyclodextrins in the antibacterial and antiviral defense mechanism.

November 5, 2016

PhD student position in Biomedical Photonics in the group of prof. Marica Ericson. Desired qualification of the applicant is a degree in physics / chemistry / biophysics or similar. More information and application can be found at:

POST DOCTORAL POSITION:The National Center for Scientific Research (CNRS), Institute of Molecular Sciences of Orsay (ISMO)/ Université Paris-Sud, Orsay, France is seeking a suitable candidate to fill a one-year Post-Doctoral Position for the CycloN-Hit project in the subject "Engineered nanoparticles to fight severe infections".

Professor György Kéri, CEO of associated partner Vichem Ltd, passed away on July 20th, 2016 at the age of 66 after a long fight against an incurable disease. Professor Kéri was a world-wide recognized biochemist and a Professor of Semmelweis University. His outstanding research in the field of cell signaling therapy and related pharmaceuticals made him famous among professionals. He developed several kinase inhibitors for clinical trials including sunitinib, which was approved by FDA for the treatment of renal cell carcinoma and imatinib-resistant gastrointestinal stromal tumor in 2006. Sunitinib was the first cancer drug simultaneously approved for two different indications. Professor Kéri was a member of several national and international biotechnology organizations and editor of Current Signal Transduction Therapy and of Current Opinion in Molecular Therapeutics among others. He founded Vichem in 1999 to develop a kinase inhibitor library and a hit-finding technology called Nested Chemical Library™. At Vichem he has recently developed the DriverHit Library™ for inhibiting the signaling pathways activated by cancer driver genes or mutated tumor suppressor genes. Vichem joined CyclonHit as Associated Partner to share the knowledge on antibiotics against tuberculosis developed by the company. We will miss him.

July 19, 2016

Cyclolab's Cyclodextrin News is published with focus on CDs in environmental technology, as presented in ICS18, May 2016, USA.

June 9, 2016

Visit Cyclolab's Cyclodextrin News, the monthly review of cyclodextrin literature. The editorial of May edition is on "Cyclodextrin for Prevention and Treatment of Atherosclerosis" and reviews research on the potential of HPβCD as a drug. In the same issue titles of the presentations in ICS18, 21-24 May 2016, Gainesville, Florida, USA, can be found.

Moreover, click on the Apriland Marcheditions of Cyclodextrin Newswith editorials on cyclodextrin formulations of Artemisinin and Avermectin for improved treatment of serious infections.

June 9, 2016

The latest (May 2016) Review on Antimicrobial Resistance Review is a very interesting and highly publishized document in the general press that presents the great threats of AMR and proposes ten measures to be adopted by the public health care system and governments to contain the problem.

May 30, 2016

The 3rd Cyclon Hit Summer School "Photoactivable antibacterials: from basic concepts to practical applications" organised by CycloN Hit partners Dr. I. Manet (CNR, Bologna, Italy) and Prof. S. Sortino (U. Catania, Italy) will be held in CNR Bologna, Italy, September 26-28, 2016. Please click for the Flyer, the 1st Circular with details and the Preliminary program. Registration has no expiry date, but is requested before July 15.

May 6, 2016

The 3rd Cyclon Hit Workshop "From Cyclodextrins to Nanoparticles: Synthesis and Applications" was successfully concluded at the University of Almeria, Spain on April 21st, 2016, organized by Prof. A. Vargas-Berenguel and his group. It comprised interesting topics on cyclodextrin chemistry and bio-applications. Additionally, a complementary skills lecture, "Scientific Writing", by prof. R. Thompson, U. Almeria, was much appreciated by both junior and senior researchers.

April 11, 2016

The 3rd Workshop (see program above) and the next Project Meeting will be held at the University of Almeria, Spain. Both events will be organized by Prof. A. Vargas-Berenguel.

The activity “Welcome to the MICRO and NANOworld: the body and the medicines. Are you curious to see how the body tissues appear under the microscope? Have you already heard about the new generation of medicines, the nanoparticles?” was displayed with microscope to visualize particles, videos and powerpoint about nanoparticles and resistant infections. Many primary and high school children visited the two-day event.

The last issue of Cyclodextrin News in this year is available.A novel application field was discovered by the group of Prof. Arima (including also the Szejtli-Prize winner Prof. K. Motoyama):HPBCD was found effective in inhibition of leukemic cellproliferation at various leukemic cell lines. Read the editorial on "HPBCD as Anticancer Drug (Resumé of PlosOne 10(11):e0141946)”.

November 10, 2015

Post Doctoral position is available at NCSR "Demokritos", Athens, Greece. STARTING DATE: January 11, 2016 or according to agreement; DURATION: 12 months; a recent ( ≤5 years research experience,after the MSc degree, at the time of hiring) PhD (doctorate) degree in Chemistry or Pharmaceutical Sciences is required. Click here for details. POSITION CLOSED

The International symposium "Advances in nanoparticulate carriers: applications in diseases and infections" that took place at the Institute Pasteur has just been concluded. It was a truly exciting 3-day symposium with intriguing lectures and discussions on the latest and greatest science on nanoparticles and their possible nanomedical applications. The symposium was also the forum for presentation of over 60 posters and a collection of scientific instruments comprising a small but interesting exhibition. The event additionally presented an opportunity of networking and exchanging views with scientists from other EU funded projects. The participation of numerous (> 280) scientists, especially young researchers and students, made the symposium a big success.

October 21, 2015

The e-version of the elegant Cyclon Hit Newsletter has been published. In the newsletter one can have a short overview of the threatening issue of bacterial infections, mini introductions on nanocarriers for antibacterial agents, selected research highlights and early results as well as allnetwork activities and output since the begining of the project.

More than 150 people including young students from schools and colleges participated in the event. The students learned to prepare « green» nanoparticles and participated in numerous discussions about nanomedicine and resistant bacteria.A CyclonHit poster was presented by MC Fellows E. Pancani and G. Salazano.

October 5, 2015

NEW e-LECTURE in the E-class collection: Lecture 1-Cyclodextrins: History and Chemistry, prepared by Drs. Eva Fenyvesi and István Puskás of patner Cyclolab SA, Budapest. Click and enjoy!

In the E-classes tab (left pane) five extremely interesting lectures can now be found. Watching all five videos significantly deepens our knowledge on cyclodextrins and their pharmaceutical applications.

WATCH the E-class Videosuploaded.Excellent presentations have been prepared by Professor Thorsteinn Loftsson, University of Iceland, a world expert on the subject.

April 27, 2015

Post-Doctoral Position:The Institute of Molecular Sciences, University Paris Sud, Orsay, is seeking a motivated fellow for a two-years Post-Doctoral Position in the frame of the Cyclon-Hit project.

Deadline for application: June 1st, 2015.Anticipated starting date: September 1st, 2015 or according to agreement. Click here for details.

April 20,2015

Post-doctoral position:The Intitut Pasteur de Lille CIIL - Center of Infection and Immunity of Lille, France is seeking a suitable candidate to fill a three-years Post-Doctoral Position for the CycloN-Hit project (and an ERC Grant INTRACELLTB). Click here for details

April 7, 2015

Post-Doctoral Position:The Laboartory of Structural and Supramolecular Chemistry, Institute of Nanoscience & Nanotechnology, NCSR "Demokritos", Athens, Greece, is seeking a suitable candidate to fill a one-year Post-Doctoral Position for the Cyclon-Hit project.Deadline: May 15, 2015.Anticipated starting date: June 15, 2015 or according to contract. Click here for details.

The next CycloN Hitmeeting and Workshop will be held in Budapest May 7 & 8, 2015.

Follow this page for more details.

February 13, 2015

The January issue ofCyclodextrin Newsis now available from CycloLab with the latest scientific literature on cyclodextrins. Main article is about "Cyclodextrins in artificial fertilization of animal", by Dr. Eva Fenyvesi.

The latest issue ofCyclodextrin News is now available from CycloLab with the latest scientific literature on cyclodextrins.

November 5, 2014

The October issue of Cyclodextrin News is now available from CycloLab. The editorial points out the notable increase in patents related to Cyclodextrins.

October 20, 2014

The 1st Summer School of CycloN Hit "Nanomaterials for Bioapplications: focus on antimicrobial research" was successully concluded on October 2nd, 2014. The numerous participants enjoyed lectures and labs both at NCSR "Demokritos" and the Hellenic Pasteur Institute. The school was followed by the CycloN Hit Scientifific meeting, held at the Hellenic Pasteur Institute on October 3, 2014.