Showtime’s dramedy “Nurse Jackie,” which stars Edie Falco, will return for a sixth season, according to the network.

Falco follows nurse Jackie Peyton, who works in a hospital in New York and struggles with personal problems. Other stars on the show include “Twilight” actor Peter Facinelli and Merritt Wever.

“’Nurse Jackie' is an essential part of the Showtime brand, and we are thrilled with the series' growth in its fifth season," president of entertainment for Showtime David Nevins said in a statement. "Under the new leadership of Clyde Phillips, and with an amazing cast led by Edie Falco, this show is as sharp and compelling and entertaining as ever. I'm excited to get to see the next chapter in Jackie's life.”

As noted by Nevins, the show came under new command after its fourth season when Clyde Phillips became the showrunner, taking over for show creators Liz Brixius and Linda Wallem. In an interview with Deadline, Wallem said traveling between Los Angeles and New York, the show’s setting, had been challenging.

“This has been the best job of my life, but the travel, having to spend six months [in L.A.] and six months [in N.Y.] and be away from home, took a toll on me,” she said.

Before the show began, Brixius said she wanted to show how important nurses are in a hospital.

“Every medical show out there has been about doctors,” Brixius told the New York Daily News. “Doctors are absolutely unable to do what they have to do without nurses. We want to tell those stories.”

Falco has been nominated twice for an Emmy and won in 2010 for her role on the show, adding to the three Emmy statuettes she earned playing Mob wife Carmela Soprano on the HBO drama “The Sopranos.” She has also been nominated twice for a Golden Globe for her work on “Nurse Jackie.”