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Abstract

Studies related to tissue interactions, especially
between epithelium and connective tissue, have been the
topic of many investigations reported in the medical
literature. Recently this type of research has been
introduced in dentistry. A major area has been tooth
organogenesis; however, there are also studies on the
interactions that occur normally in the oral mucosas.
From reviewing the literature it has been suggested that
connective tissue is the reservoir of the "factor" that
determines the epithelial specificity during fetal life
and governs its maintenance throughout life.
The purpose of this study was to determine whether
connective tissue grafts taken from a keratinized area
would carry with it the specificity for the epithelium
when transplanted beneath other epithelium and connective
tissue of a nonkeratinized zone.
The results suggested that the connective tissue did
not have any effect on the recipient zone, neither from
the clinical nor histological point of view.

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Thesis (D.Sc.D.)--Boston University School of Graduate Dentistry, 1974. Periodontics.

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