Genomes and Genes

Species

Ramal Moonesinghe

Summary

Publications

Evaluation of family history as a risk factor and screening tool for detecting undiagnosed diabetes in a nationally representative survey population

Susan HaririOffice of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, Georgia, USAGenet Med 8:752-9. 2006

Most published research findings are false-but a little replication goes a long way

Ramal MoonesingheNational Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of AmericaPLoS Med 4:e28. 2007

Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994

Detail Information

Publications22

Evaluation of family history as a risk factor and screening tool for detecting undiagnosed diabetes in a nationally representative survey population

Susan HaririOffice of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, Georgia, USAGenet Med 8:752-9. 2006

..We examined the utility of a three-level familial risk stratification system as a screening tool for diabetes in a nationally representative sample of the U.S. adult population...

Most published research findings are false-but a little replication goes a long way

Ramal MoonesingheNational Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of AmericaPLoS Med 4:e28. 2007

Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994

..Epidemiologic parameters involved in computation of disease risk have substantial uncertainty, and cumulative uncertainty should be properly recognized. Reliance on point estimates alone could be seriously misleading...

Difference in Health Inequity between Two Population Groups due to a Social Determinant of Health

..With the availability of more SDH variables and methods that distinguish linear from non-linear associations, geographic area-based analysis of disease incidence and SDH can add value to public health prevention and control programs...

The effects on population health status of using dedicated property taxes to fund local public health agencies

Peggy A HonoréDepartment of Community Health Sciences, University of Southern Mississippi, Hattiesburg, MS 39406, USABMC Public Health 11:471. 2011

..We investigated for an association of locally dedicated property taxes to fund local public health agencies and improved health status in the eight states designated as the Mississippi Delta Region...

..Study findings suggest that adding family history of diabetes can provide significant improvements in detecting undiagnosed diabetes in the US population. Further research is needed to validate the authors' findings...

..Therefore, some true associations may not be practically possible to replicate with consistency, no matter how large studies are conducted. Efforts should be made to minimize between-study heterogeneity in targeted genetic effects...

Inflammation gene variants and susceptibility to albuminuria in the U.S. population: analysis in the Third National Health and Nutrition Examination Survey (NHANES III), 1991-1994

..While the underlying etiology is unclear, chronic, low-grade inflammation is a suspected key factor. Genetic variants within genes involved in inflammatory processes may, therefore, contribute to the development of albuminuria...

Genomic medicine and racial/ethnic health disparities: promises, perils, and the challenges for health care and public health policy