Browse our anti-IL7 (IL7) Antibodies

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anti-Interleukin 7 Antibodies (IL7)

On www.antibodies-online.com are 248 Interleukin 7 (IL7) Antibodies from 27 different suppliers available. Additionally we are shipping IL7 Proteins (109) and IL7 Kits (91) and many more products for this protein. A total of 453 IL7 products are currently listed.

The observations suggest that IL-7 may play a role in the pathogenesis of Graves' disease and may be associated with its clinical activity.

IL-7 and SCF (show KITLG Antibodies) are elevated for a prolonged period after double umbilical cord blood transplantation and persistently high levels of these cytokines may correlate with worse clinical outcomes.

Common gamma-chain (show IL2RG Antibodies) cytokines IL-2 (show IL2 Antibodies), IL-7, and IL-15 (show IL15 Antibodies) prevent differentiation of naive T cells in vitro and limit activation of primed T cells in the absence of antigenic stimulus, which can contribute to the formation of cytokine imbalance.

In view of the important role IL-7 plays in lymphocyte proliferation, homeostasis and survival, down regulation of CD127 (show IL7R Antibodies) by Tat (show TAT Antibodies) likely plays a central role in immune dysregulation and CD4 (show CD4 Antibodies) T-cell decline

decreased IL-7 in peripheral blood, maybe, is a consequence of the negative feedback of the pro-inflammatory function in ITP (show ITPA Antibodies) patients.

Septic patients showed the lowest levels of IL-7. Patients with severe sepsis reached levels of IL-7 higher than those observed in the groups of uncomplicated sepsis and septic shock.

Mouse (Murine) Interleukin 7 (IL7) interaction partners

functional Gimap5 is required for optimal signaling through TCR and IL-7R in T cells.

continuous IL7 signaling was not required for tumor regression, although LIP of naive CD8 (show CD8A Antibodies)+ T cells is usually regulated by IL7

IL7 represses the follicular helper T cell gene program.

This study uncovers the metabolic mechanisms by which IL-7 tailors the metabolism of memory T cells to promote their longevity and fast response to rechallenge.

reduced surface expression of IL-7R and concomitant limited responsiveness to IL-7 signals as a common mechanism resulting in reduced cell survival of common lymphoid progenitors and thymocytes at the double-negative to double-positive transition

IL7 Antigen Profile

Antigen Summary

The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.