This policy setting causes the run once list, which is the list of programs that Windows Vista runs automatically when it starts, to be ignored. This policy setting differs from the Do not process the legacy run list setting in that programs on this list will run once the next time the client computer restarts and an administrator logs on. Setup and installation programs are sometimes added to this list to complete installations after a client computer restarts. If you enable this policy setting, attackers generally cannot use the run once list to launch rogue applications, which was a common method of attack in the past. A malicious user can exploit the run once list to install a program that may compromise the security of Windows Vista-based client computers, however since editing this list requires administrator privileges the importance of configuring this setting is not high.