This valuable addition to the literature offers readers a comprehensive overview of recent brain imaging research focused on reading, writing and mathematics―a research arena characterized by rapid advances that follow on the heels of fresh developments and techniques in brain imaging itself.

Lunatic: The Rise and Fall of an American Asylum tells of one hundred and thirty years of history, detailing the trials and tribulations of the Trans-Allegheny Lunatic Asylum. Unlike any other book about a Kirkbride Building, a portion of all proceeds are used to preserve a 157 year old National Historic Landmark, the oldest and most intact Kirkbride in existence. The author Edward Gleason has worked as the Historian for Trans-Allegheny Lunatic Asylum since its purchase at auction in 2007. The Trans-Allegheny Lunatic Asylum, constructed between 1858 and 1881, is the largest hand-cut blue sandstone building in the Western Hemisphere and 2nd largest in the World.. This Gothic structure was the end of the line for West Virginias insane for 130 years....

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Cardiovascular disease refers to the class of diseases that involve the heart or blood vessels. While the term technically refers to any disease that affects the cardiovascular system, it is usually used to refer to those related to atherosclerosis. Chronic heart failure (CHF) has emerged as a major worldwide epidemic. This book gathers the latest research in cardiovascular disease with a focus on such topics as electrical restitution and ventricular tachyarrhythmia; radiation hazards in cardiac intervention; surgical management of chronic ischemic mitral regurgitation; platelet biology in the pathophysiology of cardiovascular disease and the role of HMGB1 in cardiac dysfunction during septic shock.

K 4 teachers, homeschoolers, camp leaders, and naturalists will find the standards-based lessons in this slim volume the perfect introduction to environmental science for young learners. Hop Iinto Action helps teach children about the joy of amphibians through investigations that involve scientific inquiry and knowledge building. Developed in response to a global amphibian extinction crisis, this book will equip children with the necessary tools to protect amphibians and their environments. Twenty hands-on learning lessons such as Frog Pond Lifeguard and Camouflaged Critters can be used individually or as a yearlong curriculum. Each lesson is accompanied by detailed objectives, materials lists, background information, step-by-step procedures, evaluation questions, assessment methods, and additional web resources. The activities can easily be integrated into other disciplines such as language arts, physical education, art, and math and are adaptable to informal learning environments.

In many physical problems several scales are present in space or time, caused by inhomogeneity of the medium or complexity of the mechanical process. A fundamental approach is to first construct micro-scale models, and then deduce the macro-scale laws and the constitutive relations by properly averaging over the micro-scale. The perturbation method of multiple scales can be used to derive averaged equations for a much larger scale from considerations of the small scales. In the mechanics of multiscale media, the analytical scheme of upscaling is known as the Theory of Homogenization.The authors share the view that the general methods of homogenization should be more widely understood and practiced by applied scientists and engineers. Hence this book is aimed at providing a less abstract treatment of the theory of homogenization for treating inhomogeneous media, and at illustrating its broad range of applications. Each chapter deals with a different class of physical problems. To tackle a new problem, the approach of first discussing the physically relevant scales, then identifying the small parameters and their roles in the normalized governing equations is adopted. The details of asymptotic analysis are only explained afterwards.

Homing Endonucleases: Methods and Protocols aims at providing molecular biologists with a comprehensive resource to identify and characterize homing endonucleases from genomic sequence, to deduce the biological basis of binding and cleavage specificity, as well as to provide protocols to redesign endonuclease target specificity for genome-editing applications. Engineering of designer homing endonucleases has set the stage for genome editing of complex eukaryotic genomes with a broad range of potential applications including targeted gene knockouts in model organisms and gene therapy in humans, making this book a valuable resource for future research. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Homing Endonucleases: Methods and Protocols serves as a key reference for all labs studying site-specific DNA endonucleases.

The 17 chapters of "How to Gain Gain" give a detailed insight into a collection of the most common gain producing and constant current generating possibilities (28) of triodes for audio pre-amplifier purposes. These chapters also offer complete sets of formulae to calculate gain, frequency and phase responses of certain building blocks built-up with this type of vacuum valve (tube). In all cases detailed derivations of the gain formulae were also presented.All what is needed are the data sheet valve characteristic figures of the triode's mutual conductance, the gain factor and the internal plate (anode) resistance. To calculate frequency and phase responses of gain stages the different data sheet based input and output capacitances have to be taken into account as well. To calculate transfer functions for any kind of triode driven gain stage, including all its bias setting, frequency and phase influencing components, example MathCad worksheets as a second part of each chapter allow easy follow-up and application of the respective formulae. In addition, to demonstrate the differences of feedback and non-feedback relationships, in the last chapter and on MathCad basis, a very extensive and complete calculation example for a three stage linear pre-amplifier as well as a three stage RIAA equalized phono amplifier plays the wind up role of the book.

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This collection of essays brings together in one convenient place the detailed insights of one of the leading experts in the interpretation of Scripture in the Second Temple period. The essays are beautifully crafted, thoroughly engaged with the primary texts, very well honed methodologically, and highly informative. These volumes are sure to become a key reference point not only for scholars of the Scrolls, but also for all those interested in the concerns and approaches of Jewish interpretation in the past. George J. Brooke, University of Manchester For some time I have been hoping Moshe Bernstein's essays, which are models of scholarship, would be gathered into a convenient collection and I am delighted that Brill has published thirty of them in this two-volume work. Reading and Rereading Scripture at Qumran is an exceedingly rich resource for the student of scriptural interpretation in the Scrolls. James C. VanderKam, University of Notre Dame In our constantly expanding appreciation of the place of scriptural interpretation in the Dead Sea Scrolls, and its important implications for what came before and after, the voice of Moshe Bernstein has been one of the most persistent, responsible, and respected. It is a singular service to the study of the history and literature of ancient Judaism for his many cutting-edge contributions to be available now in one place. These volumes demonstrate just how many and manifold have been the fruits of Moshe Bernstein's labors, as much for his defining of outer literary boundaries and as for his penetrating of inner exegetical dynamics. Steven Fraade, Yale University

In this concise practical guide the Editor and Authors combine a symptoms- and problem-based approach with systematic coverage of lung disease - to help students and young professionals to understand respiratory medicine in the round.The first section of the book is devoted to the underlying principles and clinical skills needed - science and disease process, symptoms and signs, examination, and tests. The second section deals with disease specific material, giving due weight and explanation to more common conditions. The third section covers respiratory pharmacology, and the fourth consists of multiple choice review questions. The book is illustrated throughout by case studies, plus photos and diagrams in full colour.Care of patients with respiratory illness is given by a multidisciplinary team, and Understanding Respiratory Medicine is designed to appeal to medical students, young doctor, specialist nurses, physiotherapists, physiological measurement technicians and clinical scientists.

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Help students read mathematics content! This 2nd edition resource was created to support Common Core State Standards, and provides an in-depth research base about literacy instruction, and includes key strategies to help students read and comprehend mathematics content. Offers detailed approaches and activities with classroom examples by grade ranges (1-2, 3-5, 6-8 and 9-12) and includes graphic organizer templates and digital resources to help teachers implement quickly and easily. Specific suggestions for differentiating instruction are also provided to help English language learners, gifted students, and students reading below grade level.

This title features 40 new and significant house designs submitted by 40 architectural practices around the world including ODBC-Paris, Tonkin, Swatt Architects, Saia Barbarese Topouzanov, Paul Morgan Architects, Mark Dziewulski, K. Fujimoto Architect, Elmslie Osler Architect and bgp arquitectura. Each of these inspirational designs is richly illustrated with photographs and detailed plans.

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In this volume, Joseph Catalano offers an in-depth exploration of Jean-Paul Sartre's four major philosophical writings: Being and Nothingness, Saint Genet: Actor and Martyr, The Critique of Dialectical Reason, and The Family Idiot. Catalano here demonstrates the interrelation of these four works, their internal logic, and how they provide insights into important but overlooked aspects of Sartre's thought, such as the body, childhood, and evil. Readers will appreciate Catalano's subtle readings as well as the new insights that he brings to Sartre's oeuvre.

Statistics show that Canadian women now outnumber men in buying a house or condo. Women see the value in owning property. They are no longer waiting for, or expecting, a "Mr. Right" to come along before taking one of the key financial steps of their lives.Such is the case with the author of Home Girls: The Single Woman's Guide to Buying Real Estate in Canada

Do you want to create outstanding new ideas with your team?Or is your first Design Thinking Workshop just around the corner and you are looking for some guidance? Then this is the book for you. In this e-book you will learn what exactly is needed to run a successful Design Thinking Workshop which is fun and at the same time generates great results. In this e-book Pauline Tonhauser, founder of designthinkingcoach dot de, shares her best practices.

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