XADAGO Exercise

XADAGO RESOURCES

US WorldMeds can support your patients with PD with information on the XADAGO Savings Program, Prior Authorization help, or locations of participating pharmacies near them.

Xadago Prior Authorization Process

Together, US WorldMeds and PARx are helping simplify the prior authorization process.

About PARx Solutions

The mission of PARx Solutions is to help patients get the medication that
their physician believes is most appropriate for their condition.
PARx fulfills this mission by helping healthcare providers through the
Prior Authorization process.

PAs made easy

The PARx Prior Authorization Support System—or PASS—is a free
program that helps manage the PA process accurately and efficiently.
The PASS system incorporates a secure web portal, with a call center staffed
with healthcare professionals and reimbursement specialists supporting your PA needs.

For registration, visit www.PARxSolutions.com and click 'Register' OR download the following
PDF file for a complete overview about the XADAGO and PARx prior authorization process.

Xadago prescription savings program

Your patients could pay as little as $25* (save up to $125) on their XADAGO prescription each month

For more information about the XADAGO Prescription Savings
Program, please review the Terms and Conditions.

*Patients whose prescriptions will be paid for in part or in
whole by Medicare, Medicaid, or any similar federal or state
healthcare program, are not eligible for savings or rebates
according to federal and state law. Patients must visit a
participating pharmacy for savings or rebates on their XADAGO prescriptions.

Xadago Patient Support Program

Medical Inquiries and Reporting Adverse Events

For all medical inquiries, contact US WorldMeds Medical Affairs: 1-888-908-USWM (8796) or medinfo@usworldmeds.com.
To report SUSPECTED ADVERSE REACTIONS or product complaints, contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

You may also report SUSPECTED ADVERSE REACTIONS or product complaints to US WorldMeds at 1-888-4XADAGO (1-888-492-3246).

XADAGO may cause or exacerbate hypertension. Patients should be monitored after starting
XADAGO for new-onset hypertension or hypertension that is not adequately controlled.

Serotonin syndrome has been reported
with concomitant use of an antidepressant or MAO inhibitors.

Patients treated with XADAGO and other dopaminergic medications have reported falling asleep
while engaged in activities of daily living. If a patient develops daytime sleepiness or episodes of
falling asleep during activities that require full attention (e.g., driving a motor vehicle,
conversations, eating), XADAGO should ordinarily be discontinued, or the patient should be
advised to avoid driving and other potentially dangerous activities.

Dyskinesia (or exacerbations of dyskinesia), hallucinations or psychotic-like behavior, impulse
control or compulsive behaviors, and withdrawal-emergent hyperpyrexia/confusion, are
potentially associated with XADAGO.

Dietary tyramine restriction is not required during treatment with recommended doses of
XADAGO. However, patients should be advised to avoid foods containing a very high amount of
tyramine because of the potential for severe increases in blood pressure, also referred to as
hypertensive urgency, crisis, or emergency.

The maximum recommended dosage of XADAGO in patients with moderate hepatic impairment
is 50 mg once daily. XADAGO is contraindicated in patients with severe hepatic impairment. The
most common adverse reactions associated with XADAGO treatment, in which the incidence for
XADAGO 100 mg/day was at least 2% greater than the incidence for placebo were dyskinesia,
fall, nausea, and insomnia.

To report SUSPECTED ADVERSE REACTIONS or product complaints, contact US WorldMeds at 1-888-492-3246 (1-888-4XADAGO). You may also report SUSPECTED ADVERSE REACTIONS to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.