X Ray News and Research

More than one in eight people aged 75 and older in the United States develop moderate-to-severe blockage of the aortic valve in their hearts, usually caused by calcified deposits that build up on the valve's leaflets and prevent them from fully opening and closing.

In a cornfield here, past the shuttered General Motors plant and the Janesville Terrace trailer home park, a facility not seen in the United States in three decades could soon rise: a manufacturing plant that will make a vital radioactive isotope used to detect cancer and other potentially fatal maladies in millions of people every year.

Mutated RAS genes are some of the most common genetic drivers of cancer, especially in aggressive cancers like pancreatic and lung cancer, but no medicines that target RAS are available despite decades of effort.

With a mortality rate of up to 88 percent, Marburg virus can rip through a community in days. In 2005, an outbreak of Marburg virus struck a pediatric ward in the country of Angola. With no treatment available, doctors struggled to help as the virus killed 329 of 374 infected patients.

The University of Chicago Medicine began treating patients in its new, state-of-the-art adult emergency department on Friday, Dec. 27. The larger, more modern facility – the newest and most advanced of its kind in Chicago – cared for about two dozen patients within its first three hours.

Scientists at The Scripps Research Institute have peered deep into the heart of a key protein used in drug design and discovered dynamic structural features that may lead to new ways to target diseases.

Biophysicists have shown that following low-dose exposure to X-rays (at 80 milligrays), stem cells remain healthy, proliferate, and do not accumulate DNA damage to be passed on to their progeny. The paper was published in the journal Aging.

Is surgery the best option or not, in the case of cancer in the head and neck? As the consequences for speaking and swallowing may be severe, some way of predicting these consequences would help in the decision-making.

Not all patients with blood clots in their legs – a condition known as deep vein thrombosis – need to receive powerful but risky clot-busting drugs, according to results of a large-scale, multicenter clinical trial.

A review of a state program launched two years ago to improve recovery and reduce recidivism among felony offenders who have mental health or addiction issues shows the program is producing positive results.

An international team of researchers from the Moscow Institute of Physics and Technology, Forschungszentrum Jülich, the European Synchrotron Radiation Facility, the Institut de Biologie Structurale, and the Max Planck Institute of Biophysics has determined the 3-D structure of channelrhodopsin 2, a membrane protein widely used in optogenetics to control nerve cells with light.

In this interview, AZoNetwork speaks to Knauer about the use of FPLC for purification of proteins and
how their products enable scientists to get the most of liquid chromatography; conducted by Matthew Rafferty

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