Volquez out early, Padres drop opener to Mets 11-2

San Diego Padres catcher Nick Hundley watches manager Bud Black take the ball from San Diego Padres relief pitcher Brad Brach after Brach gave up a grand slam home run to New York Mets' Collin Cowgill in the seventh inning on Opening Day of a baseball game at Citi Field on Monday, April 1, 2013 in New York. (AP Photo/Kathy Kmonicek)
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San Diego Padres catcher Nick Hundley watches manager Bud Black take the ball from San Diego Padres relief pitcher Brad Brach after Brach gave up a grand slam home run to New York Mets' Collin Cowgill in the seventh inning on Opening Day of a baseball game at Citi Field on Monday, April 1, 2013 in New York. (AP Photo/Kathy Kmonicek)
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New York Mets fans Maya Joyce and her twin brother, Aidan, right, with their friend, Jacob Manthey of Montclair, N.J., show their enthusiasm for their team as they watch batting practice before the Opening Day baseball game against the San Diego Padres at Citi Field on Monday, April 1, 2013 in New York. (AP Photo/Kathy Kmonicek)— AP

New York Mets fans Maya Joyce and her twin brother, Aidan, right, with their friend, Jacob Manthey of Montclair, N.J., show their enthusiasm for their team as they watch batting practice before the Opening Day baseball game against the San Diego Padres at Citi Field on Monday, April 1, 2013 in New York. (AP Photo/Kathy Kmonicek)
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The New York Mets and the San Diego Padres line Citi Field during Opening Day ceremonies of a baseball game on Monday, April 1, 2013 in New York. (AP Photo/Kathy Kmonicek)— AP

The New York Mets and the San Diego Padres line Citi Field during Opening Day ceremonies of a baseball game on Monday, April 1, 2013 in New York. (AP Photo/Kathy Kmonicek)
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New York Mets' John Buck (44) and Daniel Murphy (28) greet Collin Cowgill (4) at home plate after Cowgill hit a grand slam off San Diego Padres relief pitcher Brad Brach scoring Buck, Reuben Tejada and Jordany Valdespin in the seventh inning of an opening day baseball game at Citi Field on Monday, April 1, 2013 in New York. (AP Photo/Kathy Kmonicek)— AP

New York Mets' John Buck (44) and Daniel Murphy (28) greet Collin Cowgill (4) at home plate after Cowgill hit a grand slam off San Diego Padres relief pitcher Brad Brach scoring Buck, Reuben Tejada and Jordany Valdespin in the seventh inning of an opening day baseball game at Citi Field on Monday, April 1, 2013 in New York. (AP Photo/Kathy Kmonicek)
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San Diego Padres starting pitcher Edinson Volquez (37) throws against the New York Mets in the second inning of an opening day baseball game at Citi Field on Monday, April 1, 2013 in New York. (AP Photo/Kathy Kmonicek)— AP

San Diego Padres starting pitcher Edinson Volquez (37) throws against the New York Mets in the second inning of an opening day baseball game at Citi Field on Monday, April 1, 2013 in New York. (AP Photo/Kathy Kmonicek)
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NEW YORK 
Edinson Volquez was much more effective against international competition.

Making his third consecutive opening day start, Volquez never got an out in the fourth inning and the San Diego Padres were routed by the New York Mets 11-2 on Monday.

Jonathon Niese stepped nicely into his new role as No. 1 starter for the Mets, and Collin Cowgill's grand slam capped a splashy New York debut during a season opener that quickly turned into a colossal flop for the Padres.

"We got beat pretty solid on both sides," manager Bud Black said. "We didn't pitch well at all. Like I said all spring, you've got to pitch well and we just didn't today."

Handed the opening day assignment in place of injured Johan Santana, Niese (1-0) enjoyed a big afternoon with both his arm and bat. He breezed into the seventh inning against a San Diego lineup missing slugger Chase Headley (broken thumb) and catcher Yasmani Grandal, suspended for the first 50 games after testing positive for testosterone.

The fast-working lefty gave up Carlos Quentin's run-scoring single and Yonder Alonso's solo homer before walking off to a standing ovation with two outs in the seventh.

"He was moving the ball around. He was throwing his cutters and curveballs for strikes," Alonso said. "He kept everybody off balance and got ahead of guys. ... So we just have to be a little more aggressive."

Niese also had a perfect day at the plate, tying his career high with two hits. He slapped an RBI single in the second off Volquez (0-1), then drew a leadoff walk and scored in a three-run fourth.

Volquez helped the Dominican Republic win the World Baseball Classic last month. But he gave up six runs, six hits and three walks in three-plus innings at windy Citi Field while falling to 0-5 in six starts against the Mets.

"I was off a little bit," Volquez said. "I got behind in the count and they hit the ball pretty good."

Touted prospect Jedd Gyorko made his major league debut for the Padres with about 30 family members and friends in the stands. He stranded four runners in his first two at-bats, then grounded a double inside third base for his first hit in the sixth.

"It was a good feeling," Gyorko said. "Niese kind of had my number. I was swinging at a lot of his curveballs, and he left one up. I don't know if he was getting tired or one just got away from him."

The ball was tossed into the San Diego dugout to be saved as a souvenir for Gyorko.

"I'm going to keep it until my mom steals it," he said.

Marlon Byrd had a pair of RBI singles and fellow Mets newcomer John Buck was in the middle of three rallies as New York improved baseball's best opening day record to 34-18 (.654) despite dropping its first eight openers.