Although animal handler Eddie (Silverman) works with lots of creatures, he has a strict NO PETS ALLOWED policy and won’t let his son Billy keep adorable stray dog Beethoven and his family of puppies. But when dog-nappers steal the canine star of the movie Eddie’s working on, the studio big shots must quickly find a replacement and unexpectedly cast the lumbering canine as their next big star.

Through his rambunctious antics and larger-than-life personality, Beethoven not only crashes into Hollywood but into Eddie’s heart as well.