This has not been an easy month for Health and Human Services Secretary Kathleen Sebelius.

Republican Sen. Pat Roberts of Kansas — who learned the political ropes working for Sebelius' father-in-law, then a Kansas congressman — called for her to step down over the debut of HealthCare.gov, the problem-plagued website where people are supposed to apply for coverage under the Affordable Care Act.

Invited on the usually friendly-to-Democrats The Daily Show, Sebelius was lampooned by host Jon Stewart, who challenged her to a race of sorts: "I'm going to try and download every movie ever made, and you're going to try to sign up for Obamacare, and we'll see which happens first."

And while she was able to laugh off Stewart's opening gag, Sebelius had trouble clearly explaining why, if businesses have been given an extra year to implement Obamacare, individuals shouldn't have the same delay.

Sebelius served six years as the Democratic governor of largely Republican Kansas. She is the daughter of the late Ohio Gov. John Gilligan. University of Kansas political science professor Burdett Loomis says she remains popular at home, despite the hits she's been taking in Washington:

"This hasn't been an easy time for her. The Obamacare rollout has clearly been problematic; she pretty much got roasted on Jon Stewart; but she's been a loyal soldier to Barack Obama and I think she truly believes that Obamacare is in the best interest of the country."

Seven years ago the Bush administration unveiled Medicare Part D, which provides seniors with prescription drug benefits. The website for that program had a similarly rocky debut. The HHS secretary then was former Utah Gov. Mike Leavitt, who notes Sebelius did not make many of the key decisions regarding the rollout of Obamacare. Leavitt says he empathizes with Sebelius:

"It's much like being the pilot of an airplane full of passengers sitting on the tarmac with a series of complications you don't entirely control. It's better to say to the passengers, 'This is where we are. This is how much time we expect it'll take. ... Here's what we're doing to remedy it and here's how it's going to affect you. We're doing our best.' "

Before being elected governor, Sebelius was Kansas insurance commissioner. The Republican occupant of the job now, Sandy Praeger, says the glitches in the rollout of Obamacare are not Sebelius' fault.

"The complexity of what she's having to deal with is massive and in an environment that's been pretty politically charged, to say the least. So I have a great deal of sympathy for what she's having to work through," says Praeger. "I know she's probably very frustrated."

Praeger says calls for Sebelius to resign are totally inappropriate. And in an appearance in Phoenix, Sebelius rejected Republican demands she step down.

'The majority of people calling for me to resign I would say are people who I don't work for and who do not want this program to work in the first place," Sebelius said Thursday. "I have had frequent conversations with the president and I have committed to him that my role is to get the program up and running, and we will do just that."

Sebelius is expected to testify before a House committee investigating the Affordable Care Act's implementation as soon as Wednesday.

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Transcript

SCOTT SIMON, HOST:

The Obama Administration says, as Ron indicated, that the problems plaguing the website for the Affordable Care Act ought to be fixed by the end of next month. One person who has borne much of the blame for the website's failings is the health and human services secretary, Kathleen Sebelius. There have even been calls for her resignation. NPR's Brian Naylor has this profile.

BRIAN NAYLOR, BYLINE: This has not been an easy month for Kathleen Sebelius. Republican Sen. Pat Roberts of Kansas - who learned the political ropes working for her father-in-law, then a Kansas congressman - called for Sebelius to step down. Invited on the usually friendly-to-Democrats "Daily Show," she was lampooned by host Jon Stewart.

(SOUNDBITE OF TV SHOW, "THE DAILY SHOW")

JON STEWART: I'm going to try and download every movie ever made...

SECRETARY KATHLEEN SEBELIUS: (Laughter)

STEWART: ...and you're going to try to sign up for Obamacare, and we'll see which happens first.

(AUDIENCE LAUGHTER)

SEBELIUS: OK, OK.

NAYLOR: And while she was able to laugh off Stewart's opening gag, she had trouble clearly explaining why, if businesses have been given an extra year to implement Obamacare, individuals shouldn't have the same delay.

(SOUNDBITE OF TV SHOW, "THE DAILY SHOW")

SEBELIUS: Well, they can. They...

STEWART: Oh, they...

SEBELIUS: ...they pay a fine, they pay a fine at the end of the year, but they don't have to - I mean, they can say, "I don't want to do it." The theory is, they can't pick and choose if they're going to get hit by a bus or diagnosed with an illness. And for a lot of young folks, they're, you know, one fall on the basketball court, one auto accident away...

STEWART: Right.

SEBELIUS: ...from a lifetime of hospital bills they can't pay.

NAYLOR: Kathleen Sebelius served six years as the Democratic governor of largely Republican Kansas. She's the daughter of the late Ohio governor John Gilligan. University of Kansas political science professor Burdett Loomis says she remains popular at home, despite the hits she's been taking in Washington.

BURDETT LOOMIS: This hasn't been an easy time for her. The Obamacare rollout has clearly been problematic; she pretty much got roasted on Jon Stewart. But she's been a loyal soldier to Barack Obama, and I think she truly believes that Obamacare is in the best interests of the country.

NAYLOR: Seven years ago, the Bush administration unveiled Medicare Part D, which provides seniors with prescription drug benefits. The website for that program had a similarly rocky debut. The HHS secretary then was former Utah governor Mike Leavitt, who notes Sebelius did not make many of the key decisions regarding the rollout of Obamacare. Leavitt says he empathizes with Sebelius.

MIKE LEAVITT: It's much like being the pilot of an airplane full of passengers, sitting on the tarmac with a series of complications you don't entirely control. It's better to say to the passengers: This is where we are; this is how much time we expect it'll take place; here's what we're doing to remedy it; and here's how it's going to affect you - we're doing our best.

NAYLOR: Before being elected governor, Sebelius was Kansas insurance commissioner. The Republican occupant of the job now, Sandy Praeger, says the glitches in the rollout of Obamacare are not Sebelius' fault.

SANDY PRAEGER: The complexity of what she's having to deal with is massive, and in an environment that's been pretty politically charged - to say the least. So I have a great deal of sympathy for what she's having to work through. I know she's probably very frustrated.

NAYLOR: Praeger says calls for Sebelius to resign are totally inappropriate. And in an appearance in Phoenix yesterday, Sebelius rejected Republican demands she step down.

SEBELIUS: The majority of people calling for me to resign - I would say - are people who I don't work for, and who do not want this program to work in the first place. I have had frequent conversations with the president, and I have committed to him that my role is to get the program up and running; and we will do just that.

NAYLOR: Sebelius is expected to testify before a House committee investigating the implementation of the Affordable Care Act as soon as Wednesday.