The history of the entity known as Ekron is unknown, save that he is a member of the Green Lantern Corps, is very powerful and was possibly created by the Guardians of the Universe, the ancient race that have dedicated themselves defending the universe with their cosmic powers. It is also unknown if he had a complete body but more recently, he was a giant disembodied head who protects the sector of space that the planet Vengar is located in. Its eye (known as the Emerald Eye of Ekron) possess the same powers as a Green Lantern and may be easier to use and in the distant future seems destined to become seperated from him and becomes coveted by evil forces.

When Lobo, an immoral bounty hunter, was tasked with stealing his eye, he succeeded, allowing the evil Lady Styx to begin her seemingly inevitable galactic conquest. When Styx destroyed the entire sector of space he was charged with protecting, Ekron went completely insane. Eventually, Ekron found himself in an uneasy alliance with Lobo, as well as with the superheroes Adam Strange, Animal Man and Starfire, in order to stop Lady Styx. Ekron's Eye was later used to defeat Lady Styx and Ekron has not been seen since.