I wouldn't say that at all. She has Morgan Le Fay (a big Avengers and Iron Man villainess) and Viper for starters, along with Hydra.

Spider-Woman could fit into the whole supernatural genre if Marvel went that way with Dr Strange. Most of her early rogues gallery/allies are supernatural in some way: Morgan, Nekra, Brothers Grimm, Werewolf by Night, the Shroud, Hangman, etc, plus mutants like Gypsy Moth. Those early stories (and the later ones too) are quite similar in tone and premise to series like Angel. She would be right up Joss Whedon's alley.

My choices would be Spider-Woman, She-Hulk and Ms Marvel.

We have the same choices!

__________________2017 films - best to worst
Wonder Woman, Planet of the Apes, Guardians of the Galaxy, Spider-Man, Logan, Kong, Fast & Furious, Cars, Alien, Beauty and the Beast, Power Rangers, Resident Evil, The Mummy, Pirates of the Caribbean, Ghost in the Shell, Underworld, Transformers