anti-NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1) Antibodies

Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation (By similarity). Additionally we are shipping NFKB Inhibitor Interacting Ras-Like 1 Proteins (8) and and many more products for this protein.

It was demonstrated that elevated levels of mRNA for NKIRAS1 was significantly associated both with loss of methylation in NKIRAS1 CpG-islands and methylation in a number of miRNA genes.

Significant correlation was found between alterations of methylation status of miR (show MLXIP Antibodies)-34b/c, miR (show MLXIP Antibodies)-193a and the expression level of NKIRAS1 target gene in the primary lung tumors.

Low kappaB-Ras1 expression is associated with gliomas.

It was shown the decreased expression level of NKIRAS1 in Renal cell carcinoma (show MOK Antibodies)

NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1) Antigen Profile

Protein Summary

Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation (By similarity).