Pyramid and Zopache have the same geneology, but are philosophically very different. Pyramid is focussed on the needs of corporate developers. Zopache is targetted at end users. Corporate developers want to use relational databases, url dispatch, Apache, unix, github, buildout, setuptools, pypi, python, WSGI and vi. End users do not want to deal with any of those technologies, they want user-friendly browser-based technologies, like ckEditor, ACE Editor and the ZMI.