Areas of Contract Research

RNA Methylation Analysis

Comprehensive Epigenetic Services for RNA Methylation Analysis

Overview

An important modification of note is that of methylated RNA. In humans, cytosine methylation of RNA has been observed in tRNAs, rRNAs, mRNAs, and non-coding RNAs (ncRNAs). The functional relevance of this modification remains unclear, but recent data suggest that RNA cytosine methylation affects the regulation of various biological processes such as RNA stability, processing and mRNA translation. For your gene expression or non-coding RNA studies, our comprehensive 5-methylcytosine (5-mC) service offers transcriptome-wide coverage of total RNA or miRNA by identifying methylated cytosines in RNA. N6-methyladenosine (m6A), the most abundant epigenetic modification in RNA of eukaryotic cells, can be efficiently quantified using our proprietary, ELISA-based global N6-methyladenosine (m6A) quantification service.

Services

5-mC RNA SeqIdentifies methylated cytosines in transcriptome-wide coverage of total RNA or miRNA