At-risk communities in the Midwest are becoming more vulnerable to climate change impacts such as flooding, drought, and increases in urban heat islands. Tribal nations are especially vulnerable because of their reliance on threatened natural resources for their cultural, subsistence, and economic needs. Integrating climate adaptation into planning processes offers an opportunity to better manage climate risks now. Developing knowledge for decision-making in cooperation with vulnerable communities and tribal nations will help to build adaptive capacity and increase resilience.