I think it is more the first option you've suggested due to the addition of καὶ ἐφανέρωσεν τὴν δόξαν αὐτοῦhad it not been added, the second option would have been the default (location of action, but first action within that location).

there is a third possibility however, that his previous signs elsewhere up to this first one in Cana weren't so grand as to lend him his goodrepute/glory (the heresy! )

of course, i haven't read anything in the new testament to actually know if this was (at least from what is written) the first sign he'd ever performed. others who have, I'm sure, will reply soon enough.