Alpha Hydroxy Acids transformed
the modern cosmetic market. Instead of relying on statistics, consumers could
literally feel and see an immediate difference in their skin – a smooth,
brighter complexion with a diminished appearance of unwanted wrinkles. FSS
Fruit Mix contains natural Alpha Hydroxy Acids (AHAs). This product is capable
of improving moisturization while simultaneously increasing the production of
structural components, such as collagen and glycosaminoglycan, as well as
reversing cutaneous atrophy. FSS Fruit Mix is the way to smooth, wrinkle-free
skin, truly revealing a rejuvenated complexion!

A contributing factor to AHA
efficacy is its differentiation from other organic acids. AHAs have a hydroxyl
(OH) group in the alpha position that is relative to the carboxyl (COOH) group.
Theories for the mechanism of AHA-activity range from the sequestration of Ca2+
and the associated disruption of divalent metal cation-dependent cell adhesion
molecules to the roles of AHAs as intermediates in a variety of metabolic
pathways. FSS Fruit Mix will work to help brighten skin, shed the dullness, and
deliver much needed therapeutic benefits so you can shine.

The topical use of AHAs dates back to the beginning of recorded
history. Traditional skin care treatments for softening skin have included milk
and lemon juice, both of which contain AHAs. Since then, products comprised of
AHAs have become widely used in cosmetics. Consumer attention was first
captured when AHA products incorporating fruit and sugar derivatives were
initially marketed towards acne treatments, anti-aging products and
hyperpigmentation applications. From capabilities such as smoothing fine lines
to help minimize the appearance of wrinkles, AHAs are favored for improving
skin tone and condition, while enhancing overall texture.

FSS Fruit Mix is based on a
standardized extraction of five plant species: Bilberry, Sugar Cane, Orange,
Lemon, and Sugar Maple. These botanical extracts deliver five natural AHAs to
the skin: Lactic Acid (from Bilberry), Glycolic Acid (from Sugar Cane), Citric
Acid (from Orange and Lemon), and Malic and Tartaric Acids (from Sugar Maple).
These AHAs are commonly used to treat skin conditions such as rough skin,
surface wrinkles and fine lines. Recognized for having exfoliating properties,
AHAs leave the skin with a smooth and radiant appearance.

Glycolic acid, the smallest molecular
structure of the group, has proved effective in cosmetics due to its ability to
reach the deeper layers of the skin, thus making it an excellent exfoliating
agent that provides immediate skin softening effects. Glycolic acid loosens
corneocyte attachments and reduces cell cohesion at the lower level of the
stratum corneum to promote cellular renewal. As new skin cells generate, older
cells slough off to reveal smoother looking skin. Factors such as sun damage,
age and environmental stress slow down this process which results in the
accumulation of dead skin cells. The use of alpha-hydroxy acids can combat the
problem by breaking proteolytic bonds to increase cellular renewal. Moreover,
glycolic acid allows the capillaries to dilate and deliver more oxygen and
energy to the cells for increased intracellular efficiency. In addition to
increasing collagen and glycosaminoglycan (GAG) synthesis, Glycolic acid
treatments also increase type I collagen mRNA and hyaluronic acid content of
human skin.

Lactic acid is an excellent
moisturizing ingredient and beneficial for most hyper-proliferate skin
conditions. One of the key benefits for using lactic acid in anti-aging
applications is that research has also shown it is capable of reversing
cutaneous atrophy. This will help thicken the skin to create a more youthful
aesthetic. Citric acid is an intermediate in the Krebs cycle and is integral
for ATP production, which helps to promote healthy skin by stimulating the
formation of fibrous protein. The Krebs cycle, also known as Citric Acid,
occurs in the mitochondria of our cells. This cycle is responsible for
metabolizing sugar intake thus breaking it into carbon dioxide, water, and
energy. In skin biology, Citric Acid provides cells with a source of useable
energy. This, in turn, contributes to the factors that chemically
exfoliate the outer layer of the epidermis. Malic and tartaric acids also
influence skin tone and have been shown to increase elasticity, which is an
important factor to enhancing complexion clarity.

BENEFITS

FSS Fruit Mix works to brighten
skin, leaving any signs of dullness behind! FSS Fruit Mix helps normalize the
skin by weakening corneocyte adhesion along the stratum corneum to improve
exfoliation and enhance cellular proliferation. Incorporating FSS Fruit Mix
into final formulas provides consumers with the tactile proof of the product’s
efficacy, instantly softer, smoother skin. FSS Fruit Mix can further be used in
personal care products to help moisturize the skin and decrease the appearance
of wrinkles. FSS Fruit Mix is the way to smooth, wrinkle-free skin, truly
revealing a rejuvenated complexion!

Although the FDA has approved
AHAs for use applications such as increasing cell turnover rates and reduc­ing
stratum corneum thickness, we recommend that you consult your legal counsel
prior to marketing your product to reduce the risk of patent infringement.

Figure 1. The comparison of therapeutic
indices suggests that FSS Fruit Mix rates higher on the therapeutic
index than both synthetic glycolic and lactic acids

To measure improvements in cell renewal, a skin patch study was
performed on the volar forearms of 10 participants between the ages of 22 and
43. The premise of the study was to visually measure improvements in the rate
of exfoliation of skin treated with FSS Fruit Mix compared to untreated
skin. This was achieved by applying fluorescent dye to the skin and counting
the days required until the dye was no longer visible. The results indicate
that FSS Fruit Mix is capable of increasing the rate of cell renewal by
24% and 38% compared to the untreated control

Storage: Protected from direct light and humidity at a
temperature of 50°-77°F (10°-25°C) Shelf life: 12 months, properly stored, in sealed container.This product should be added to a formulation at
the recommended usage rate