GenomeSpace Tools and Data Sources

Cancer Cell Line Encyclopedia

Datasets from the Cancer Cell Line Encyclopedia (CCLE) project are now linked to GenomeSpace. The CCLE project aims to characterize the genetics and pharmacology of a large panel of human cancer models and to develop integrated computational analyses that link pharmacologic sensitivities to genomic patterns. In addition to the pharmacologic analysis and annotations for about 1000 cell lines, data include DNA copy number, mRNA expression, Oncomap 3.0 mutation, and hybrid capture mutation analyses. The project is ongoing and datasets may be released before publication.