Medical Xpress news tagged with:chemotherapy drugshttp://medicalxpress.com/
en-usMedical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine.IKZF1 gene mutations found to increase hereditary risk for ALL in childrenA late-breaking abstract being presented today during the 58th American Society of Hematology (ASH) Annual Meeting and Exposition in San Diego identifies inherited genetic mutations in the gene IKZF1 that confer a higher likelihood of developing pediatric acute lymphocytic leukemia (ALL). The findings are among the latest evidence to point to a strong inherited genetic basis of ALL risk in children. Some of the variants identified also appear to reduce cancer cells' sensitivity to a chemotherapy drug used to treat some types of ALL, potentially contributing to drug resistance.http://medicalxpress.com/news/2016-12-ikzf1-gene-mutations-hereditary-children.html
CancerTue, 06 Dec 2016 10:44:12 ESTnews400243439Juno Therapeutics halts study after more patient deathsJuno Therapeutics again halted its study of an experimental leukemia treatment Wednesday after two more patients died of complications.http://medicalxpress.com/news/2016-11-juno-therapeutics-halts-patient-deaths.html
OtherWed, 23 Nov 2016 10:59:25 ESTnews399121158Study shows low-dose chemotherapy regimens could prevent tumor recurrence in some cancersConventional, high-dose chemotherapy treatments can cause the fibroblast cells surrounding tumors to secrete proteins that promote the tumors' recurrence in more aggressive forms, researchers at Taipei Medical University and the National Institute of Cancer Research in Taiwan and University of California, San Francisco, have discovered. Frequent, low-dose chemotherapy regimens avoid this effect and may therefore be more effective at treating certain types of breast and pancreatic cancer, according to the murine study "Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells," which will be published online November 23 in The Journal of Experimental Medicine.http://medicalxpress.com/news/2016-11-low-dose-chemotherapy-regimens-tumor-recurrence.html
CancerWed, 23 Nov 2016 09:00:02 ESTnews399097699The connection between chemotherapy and infectionMost people's ideas of bacteria and fungi tend to be negative, since we often think of them only as the cause of many human diseases. Yet we must not forget that the average human body is colonized by trillions of microbes belonging to these microbial groups. In fact, it has been estimated that the number of bacterial and fungal cells colonizing a human far exceeds that of the number of cells actually belonging to the human!http://medicalxpress.com/news/2016-11-chemotherapy-infection.html
CancerWed, 16 Nov 2016 06:57:54 ESTnews398501867Proposed clinical trial could change the game for deadly type of breast cancer University of Kentucky Markey Cancer Center Oncologist Dr. Edward Romond spent his career at UK treating and studying breast cancer, even leading major Phase 3 clinical trials on the breast cancer drug trastuzumab in the early 2000s. Commonly known as Herceptin, this drug became a standard of care for patients with HER2-positive breast cancer.http://medicalxpress.com/news/2016-10-clinical-trial-game-deadly-breast.html
CancerThu, 13 Oct 2016 06:52:37 ESTnews395560348Newly discovered immune cell type protects against lung infections during chemotherapySt. Jude Children's Research Hospital investigators have identified a new form of an immune cell that protected mice from life-threatening lung infections under conditions that mimic cancer chemotherapy. The research appears online today in the scientific journal Proceedings of the National Academy of Sciences (PNAS).http://medicalxpress.com/news/2016-09-newly-immune-cell-lung-infections.html
Medical researchMon, 26 Sep 2016 16:04:18 ESTnews394124652New immunotherapy treatment could lead to better, cheaper results for pancreatic cancerA new immunotherapy treatment has shown dramatic results in treating advanced pancreatic cancer, a deadly cancer that has seen little progress in treatment over the last 20 years.http://medicalxpress.com/news/2016-09-immunotherapy-treatment-cheaper-results-pancreatic.html
CancerFri, 09 Sep 2016 07:50:01 ESTnews392625829More chemo drugs don't improve treatment of rare bone cancerOsteosarcoma patients with tumors that haven't responded well to the standard chemotherapy regimen have unimproved outcomes and more side effects when given two additional drugs, a large international trial has found.http://medicalxpress.com/news/2016-08-chemo-drugs-dont-treatment-rare.html
CancerFri, 26 Aug 2016 06:40:01 ESTnews391411920Cancer drug for mums-to-be may curb baby girls' future fertilityChemotherapy treatment during pregnancy may affect the future fertility of unborn baby girls, a study suggests.http://medicalxpress.com/news/2016-08-cancer-drug-mums-to-be-curb-baby.html
CancerThu, 11 Aug 2016 03:20:01 ESTnews390100964Selenocompounds kill multidrug resistant cancer cells, block cells' defenses against cancer drugsNewly discovered molecules can kill multidrug resistant cancer cells by blocking cells' defenses against cancer drugs, according to a new study published in Bioorganic & Medicinal Chemistry Letters. The lead author of the research, from the University of Navarra in Spain and Jagiellonian University Medical College in Poland, hopes the findings provide an initial step towards more effective treatments in the future against resistant cancers.http://medicalxpress.com/news/2016-07-selenocompounds-multidrug-resistant-cancer-cells.html
CancerThu, 14 Jul 2016 08:28:33 ESTnews387703703Study of promising cancer treatment allowed to resumeA study of an experimental treatment for leukemia that was halted last week following two patient deaths has been allowed to resume after a modification.http://medicalxpress.com/news/2016-07-cancer-treatment-resume.html
CancerTue, 12 Jul 2016 17:51:41 ESTnews387564692Scientists create 'guided chemotherapy missiles' that target cancer cells and spare healthy onesThere's a good, bad and ugly to cancer chemotherapy. The good is that the drugs do often effectively kill cancer cells. The bad is that the drugs also damage other quickly dividing cells in the body, causing side effects ranging from cosmetic, like hair loss, to disabling.http://medicalxpress.com/news/2016-06-scientists-chemotherapy-missiles-cancer-cells.html
CancerThu, 16 Jun 2016 16:56:41 ESTnews385314989Scientists identify method of action for common chemotherapy drugsA study by scientists at Duke Health is providing insight into how certain commonly-used chemotherapy drugs work, potentially opening new ways to enhance the benefits of treatment for cancer patients.http://medicalxpress.com/news/2016-06-scientists-method-action-common-chemotherapy.html
Medical researchWed, 15 Jun 2016 06:40:58 ESTnews385191636Two-drug regimen shows promise against pancreatic cancer A combination of two chemotherapy drugs has shown promising results in fighting pancreatic cancer, significantly improving five-year survival rates, according to a European study presented Friday.http://medicalxpress.com/news/2016-06-two-drug-regimen-pancreatic-cancer.html
CancerSat, 04 Jun 2016 05:34:37 ESTnews384237253Study provides new clues to leukemia resurgence after chemotherapyFor the first time, researchers have discovered that some leukemia cells harvest energy resources from normal cells during chemotherapy, helping the cancer cells not only to survive, but actually thrive, after treatment.http://medicalxpress.com/news/2016-06-clues-leukemia-resurgence-chemotherapy.html
CancerThu, 02 Jun 2016 12:48:01 ESTnews384090456Restoring chemotherapy sensitivity by boosting microRNA levelsBy increasing the level of a specific microRNA (miRNA) molecule, researchers have for the first time restored chemotherapy sensitivity in vitro to a line of human pancreatic cancer cells that had developed resistance to a common treatment drug.http://medicalxpress.com/news/2016-05-chemotherapy-sensitivity-boosting-microrna.html
CancerFri, 27 May 2016 09:30:03 ESTnews383559622Investigating how 'chemo brain' develops in cancer patientsDuring and after chemotherapy, many cancer patients describe feeling a mental fog, a condition that has been dubbed "chemo brain." Why this happens is unclear, but researchers have found a new clue to understanding this syndrome. A study in the journal ACS Chemical Neuroscience reports that chemotherapy in rats affects their chemical messengers dopamine and serotonin, which are associated with cognition.http://medicalxpress.com/news/2016-05-chemo-brain-cancer-patients.html
NeuroscienceWed, 25 May 2016 12:14:26 ESTnews383397256FDA OKs immunotherapy drugs for bladder, blood cancers (Update)U.S. regulators have approved the first drug for bladder cancer that harnesses the body's immune system, the first major advance in three decades against the most common type of bladder cancer.http://medicalxpress.com/news/2016-05-fda-oks-immunotherapy-drugs-bladder.html
CancerWed, 18 May 2016 15:42:10 ESTnews382804923Cisplatin may cause more permanent hearing loss in people with Cockayne syndromeThe chemotherapy drug cisplatin can kill cancer, but it can also cause permanent hearing loss.http://medicalxpress.com/news/2016-05-cisplatin-permanent-loss-people-cockayne.html
NeuroscienceWed, 18 May 2016 09:09:51 ESTnews382781379Heating chemotherapy drugs may improve bladder cancer treatmentScientists have found that heating the chemotherapy drug mitomycin-C prior to using it for treating bladder cancer may radically improve its efficacy. The findings, published in the International Journal of Hyperthermia, are the result of a four-and-a-half-year study by medics based at Comarcal Hospital, Monforte, Spain.http://medicalxpress.com/news/2016-05-chemotherapy-drugs-bladder-cancer-treatment.html
CancerTue, 17 May 2016 07:50:01 ESTnews382688964Low-grade brain tumors: Radiation plus chemotherapy is best treatment, trial suggestsNew clinical-trial findings show that patients with a low-grade form of brain cancer who are treated with radiation plus a combination of chemotherapy drugs have better survival than patients treated with radiation alone.http://medicalxpress.com/news/2016-04-low-grade-brain-tumors-chemotherapy-treatment.html
CancerThu, 14 Apr 2016 13:20:58 ESTnews379858847Chemotherapy delivered directly to tumors may slow pancreatic cancerPancreatic cancer is the third leading cause of cancer deaths in the United States, in part because it is very difficult for chemotherapy drugs to reach the pancreas, which is located deep within the abdomen.http://medicalxpress.com/news/2016-04-chemotherapy-tumors-pancreatic-cancer.html
CancerThu, 14 Apr 2016 07:19:30 ESTnews379837161Study suggests most female childhood cancer survivors have good chance of becoming pregnantFor women who have survived childhood cancer, the impact of modern chemotherapy regimens on the likelihood of becoming pregnant is generally small, and most have a good chance of conceiving, according to one of the largest studies of its kind published in The Lancet Oncology. In contrast, male survivors of childhood cancer are significantly less likely to have children, especially if they are treated with chemotherapy regimens containing high doses of commonly used alkylating drugs and cisplatin.http://medicalxpress.com/news/2016-03-female-childhood-cancer-survivors-good.html
CancerTue, 22 Mar 2016 19:12:22 ESTnews377892729Laser treatment may boost effectiveness of brain tumor drugsThe human brain has a remarkable defense system that filters bacteria and chemicals. For brain tumor patients, the barrier works almost too well by blocking most chemotherapy drugs.http://medicalxpress.com/news/2016-02-laser-treatment-boost-effectiveness-brain.html
CancerWed, 24 Feb 2016 14:20:19 ESTnews375546011Some chemotherapy drugs may improve tumor response to immune checkpoint therapyThe use of certain traditional chemotherapy drugs may expand the number of tumors that respond to one of today's most promising cancer therapies - immune checkpoint blockade. Researchers from the Massachusetts General Hospital (MGH) Center for Systems Biology report in the Feb. 16 issue of the journal Immunity that inducing the infiltration of cytotoxic T cells (CTLs) - immune cells that kill cancer cells and cells that are infected or in other ways damaged - into lung tumors sensitized otherwise unresponsive tumors to checkpoint blockade in animal models.http://medicalxpress.com/news/2016-02-chemotherapy-drugs-tumor-response-immune.html
ImmunologyTue, 16 Feb 2016 15:32:32 ESTnews374859139Device hits pancreatic tumors hard with toxic four-drug cocktail, sparing the bodyA highly lethal cancer sometimes requires large doses of highly toxic drugs. However, a blitzkrieg approach can be unfeasible for some patients due to severe side effects. Now a powerhouse team of researchers at the University of North Carolina at Chapel Hill has revealed that an implantable device can deliver a particularly toxic cocktail of drugs directly to pancreatic tumors to stunt their growth or in some cases, shrink them - all while showing signs that the rest of the body would be spared toxic side effects.http://medicalxpress.com/news/2016-02-device-pancreatic-tumors-hard-toxic.html
CancerMon, 08 Feb 2016 16:33:11 ESTnews374171581FDA approves halaven for advanced liposarcoma(HealthDay)—Halaven (eribulin mesylate) has been approved by the U.S. Food and Drug Administration as the first chemotherapy drug shown to improve survival in people with advanced liposarcoma.http://medicalxpress.com/news/2016-01-fda-halaven-advanced-liposarcoma.html
MedicationsFri, 29 Jan 2016 10:40:01 ESTnews373284453Unravelling the causes of an aggressive childhood cancerThe origins of a type of aggressive childhood lymphoma have been found, giving hope that new drugs could be designed to prevent the disease coming back after treatment.http://medicalxpress.com/news/2016-01-unravelling-aggressive-childhood-cancer.html
CancerWed, 13 Jan 2016 06:04:50 ESTnews371887482Immune therapy drug results in prolonged survival in advanced lung cancerA Yale-led international study in patients with advanced non-small cell lung (NSCLC) cancer resistant to chemotherapy has found a promising weapon in an immune therapy drug commonly used to treat other cancers. The findings were published Dec. 19 in The Lancet and presented at the 2015 annual conference of the European Society for Medical Oncology in Singapore.http://medicalxpress.com/news/2015-12-immune-therapy-drug-results-prolonged.html
CancerMon, 21 Dec 2015 07:21:35 ESTnews369904885Vistogard approved for chemotherapy overdose(HealthDay)—Vistogard (uridine triacetate) has been approved by the U.S. Food and Drug Administration to treat an overdose of chemotherapy drugs commonly used to treat cancers of the breast and gastrointestinal tract.http://medicalxpress.com/news/2015-12-vistogard-chemotherapy-overdose.html
MedicationsFri, 11 Dec 2015 16:50:01 ESTnews369072758