I don’t often use superlatives, but it’s easy to say that 2016 will be the most significant year yet in the battle to repeal marijuana prohibition in the United States.

Up until now, the two biggest years were 1996, when California became the first state to legalize medical marijuana, and 2012, when Colorado and Washington became the first two states to legalize marijuana for adults 21 and older.

2016 will likely comprise a cornucopia of cannabis policy advances, which I’ll enumerate in the form of predictions.