A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.4.23.28

Accepted Name

Acrocylindropepsin.

Alternative Name(s)

Acrocylindrium proteinase.

Reaction catalysed

Preference for hydrophobic residue at P1 and P1'. Action on the B chain of insulin is generally similar to that of pepsin A, but it also cleaves 6-Leu-|-Cys(SO(3)H)-7, 21-Glu-|-Arg-22 and 3-Asn-|-Gln-4, although not 4-Gln-|-His-5