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When skin is exposed to UV radiation over a long period of time, it creates a pigment called melanin in order to block the sun and protect itself. Liver spots are not precancerous, states Scrubbing In.

It is possible to lighten or remove spots with prescription bleaching creams, laser therapies, dermabrasion, cryotherapy and chemical peels, reports Scrubbing In. Because liver spots are cosmetic, not all health insurances cover their removal. Many fade creams are available over the counter in drugstores and online.