luteal cells and CL tissues and the effect of PGF 2
α on the apoptosis of luteal cells is mediated by the Slit/Robo interaction.
Materials and methods
Reagents
Rabbit IgG anti-Slit2 polyclonal antibodies and mouse IgM anti-Robo1 MABs were

per week using a Bayer Glucometer Elite. A mouse was deemed diabetic after two consecutive BG readings of >250 mg/dl. Mice were housed in accordance with the Ohio State University's requirements and regulations for animal care and use. Mice were

context of the observed in vivo tissue distribution of PANDER. Therefore, to further elucidate the physiologic role of pancreas-secreted PANDER in vivo , our laboratory has created and phenotyped the only transgenic mouse model (PANDER transgenic, PANTG

identification of extreme skeletal phenotypes in mutant mouse lines that carry single-gene knockouts representing all the known protein-coding genes. This approach has been made possible by the International Knockout Mouse Consortium (IKMC), whose aim is to

generate pulsatile GH secretion from the anterior pituitary, is one possible candidate. In mouse stomach, the endoproteolytic processing of the ghrelin molecule from its precursor (proghrelin) into mature ghrelin is facilitated by the enzyme prohormone