The Pittsburgh Pirates selected 21-year-old right-handed pitcher Bryan Bullington with the first overall pick in the 2002 First-Year Player Draft. The 6'5", 225-pound hurler was ranked by Baseball America as having the best breaking ball and best command among all college pitchers.

In his three-year career at Ball State, Bullington posted a 29–11 record, 13 complete games and a 3.36 ERA in 46 games (42 starts). He is the university's all-time leader in strikeouts (357) and was a member of the 2001 USA National team. As a freshman, Bullington garnered all-conference honors and led the MAC in strikeouts. He was also named MAC Pitcher-of-the-Year for 2001 and 2002. Bullington set a MAC record in strikeouts and led the league in victories and ERA in 2002.