The Role of Oxidative Reactions in Decompression Ischemic Edema

Abstract

Rapid decompression of an expanded extradural balloon is followed by intracranial hypertension, cerebral edema, and not uncommonly fatal outcome. Although the exact mechanism remains conjectural, it has been documented that this decompression is accompanied by cortical hypoperfusion, vascular injury of cortical microvasculature, and cerebral edema (Busto 1984, Yamaguchi 1976)

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