The present disclosure relates to a method and apparatus for coronary stenosis assessment, a storage medium, and an electronic device. The method comprises: obtaining an angiographic image of a coronary artery; performing vessel three-dimensional reconstruction according to the angiographic image to obtain a three-dimensional vessel model of the coronary artery; for a target branch of the coronary artery, performing a pressure drop test on the three-dimensional vessel model to obtain a quadratic function relationship between a blood flow rate and a blood flow pressure of the target branch, the target branch being any branch of the coronary artery; and assessing a stenosis condition of the coronary artery according to a constant coefficient of the quadratic function relationship. Embodiments of the present disclosure are used for assessing the stenosis degree of a vessel.