Medical Xpress news tagged with:genetic differenceshttp://medicalxpress.com/
en-usMedical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine.Genetic differences in amino acid metabolism are linked to a higher risk of diabetesA study published today in the journal PLOS Medicine has identified the five genetic variants associated with higher levels of the branched-chain amino acids isoleucine, leucine and valine. The researchers also found that these genetic variants were associated with an increased risk of type 2 diabetes.http://medicalxpress.com/news/2016-11-genetic-differences-amino-acid-metabolism.html
DiabetesTue, 29 Nov 2016 14:00:01 ESTnews398970239Landmark project shows heart disease and arthritis risk raised by genetic changes in bloodToday in Cell and associated journals, 24 research studies from the landmark BLUEPRINT project and IHEC consortia reveal how variation in blood cells' characteristics and numbers can affect a person's risk of developing complex diseases such as heart disease, and autoimmune diseases including rheumatoid arthritis, asthma, coeliac disease and type 1 diabetes.http://medicalxpress.com/news/2016-11-landmark-heart-disease-arthritis-genetic.html
GeneticsThu, 17 Nov 2016 12:00:04 ESTnews398594147Strain-level profiling yields new insights into mother-infant microbiomesDirect microbial sequencing of environmental samples, such as from ocean water, hospital surfaces, and the human gut, have illuminated the vast number of microbes present in our world. However, a microbial species can be genetically diverse, and this variability is often not captured during metagenomic analysis. In a study published online today in Genome Research, scientists developed a new tool to examine genetic differences within bacterial species and uncover novel transmission patterns in mother-infant microbiomes and marine metagenomes not previously appreciated by species-level analyses.http://medicalxpress.com/news/2016-10-strain-level-profiling-yields-insights-mother-infant.html
GeneticsTue, 18 Oct 2016 14:21:16 ESTnews396019267Predicting diabetes risk from birth weightDo you know how much you weighed when you were born? From that first weigh-in moments after birth, it's possible to predict your future adult health. And when it comes to disease risk in later life, it's best to be average – babies that are larger than average are at an increased risk of diabetes, while small babies are at a higher risk of both diabetes and heart disease. The reasons for this are complex, but researchers at the University of Oxford have perhaps found the biggest part of the puzzle. It's in your genes.http://medicalxpress.com/news/2016-10-diabetes-birth-weight.html
DiabetesFri, 07 Oct 2016 07:01:19 ESTnews395042473How baby's genes influence birth weight and later life diseaseNew research finds genetic differences that help to explain why some babies are born bigger or smaller than others. It also reveals how genetic differences provide an important link between an individual's early growth and their chances of developing conditions such as type 2 diabetes or heart disease in later life.http://medicalxpress.com/news/2016-09-baby-genes-birth-weight-life.html
GeneticsWed, 28 Sep 2016 17:52:37 ESTnews394303945Genes are not destiny: Environment and education still matter when it comes to intelligenceRecent research has suggested that academic performance, reading ability and IQ have a genetic basis. This reinforces the popular notion that intelligence and related cognitive capacities are somehow "in our genes".http://medicalxpress.com/news/2016-08-genes-destiny-environment-intelligence.html
GeneticsMon, 22 Aug 2016 07:35:26 ESTnews391070111Researchers discover genetic causes of higher melanoma risk in menA study led by researchers at Universitat Jaume I de Castellón has identified one of the genetic causes underlying the higher rate of melanoma in men. The results have been published in Biology of Sex Differences.http://medicalxpress.com/news/2016-07-genetic-higher-melanoma-men.html
CancerMon, 25 Jul 2016 07:18:56 ESTnews388649885Study uncovers genetic differences for kidney cancer that may contribute to survival disparity in African-AmericansA University of North Carolina Lineberger Comprehensive Cancer Center-led study has identified genetic differences in tumors of African-Americans with the most common type of kidney cancer compared with whites.http://medicalxpress.com/news/2016-03-uncovers-genetic-differences-kidney-cancer.html
CancerWed, 30 Mar 2016 05:39:33 ESTnews378535166Life history effects on the molecular clock of autosomes and sex chromosomesEvolutionary geneticists date events using the number of mutations that have accumulated since they occurred. For instance, they date the spilt time between humans and chimps by dividing the number of genetic differences between them by the rate at which new mutations arise. Recently those dates have been mired in uncertainty, with new estimates of the mutation rate suggesting that the human splits from chimps and gorillas are more than two times older than previously thought. Importantly, the new split time estimates appear to be at odds with the fossil record.http://medicalxpress.com/news/2016-01-life-history-effects-molecular-clock.html
GeneticsThu, 28 Jan 2016 19:11:23 ESTnews373230673Could there be a 'quit-smoking' gene?(HealthDay)—Some smokers have much more difficulty kicking the habit than others. Now, a new review of prior research identifies a potential culprit: genes.http://medicalxpress.com/news/2015-12-quit-smoking-gene.html
Psychology & PsychiatryThu, 03 Dec 2015 10:30:01 ESTnews368359525Discovery of genetic differences between relapsing/non-relapsing breast cancersAlthough most patients with breast cancer are cured after treatment, in about one in five the cancer will recur, returning either to the same place as the original tumour or spreading to other parts of the body (metastasis). Now, researchers have taken an important step towards understanding why some primary breast cancers return while others do not.http://medicalxpress.com/news/2015-09-discovery-genetic-differences-relapsingnon-relapsing-breast.html
CancerFri, 25 Sep 2015 02:07:07 ESTnews362365617Tall and slim: They go together, genetic study showsUniversity of Queensland scientists have found a genetic basis for height and body mass differences between European populations.http://medicalxpress.com/news/2015-09-tall-slim-genetic.html
GeneticsMon, 14 Sep 2015 12:11:53 ESTnews361451504A metabolic master switch underlying human obesityObesity is one of the biggest public health challenges of the 21st century. Affecting more than 500 million people worldwide, obesity costs at least $200 billion each year in the United States alone, and contributes to potentially fatal disorders such as cardiovascular disease, type 2 diabetes, and cancer.http://medicalxpress.com/news/2015-08-metabolic-master-underlying-human-obesity.html
Overweight and ObesityWed, 19 Aug 2015 17:00:02 ESTnews359197694Genetic variation determines response to anti-diabetic drugIn the first study of its kind, Penn researchers have shown how an anti-diabetic drug can have variable effects depending on small natural differences in DNA sequence between individuals. Mitchell Lazar, MD, PhD, Raymond Soccio, MD, PhD, and colleagues at the Perelman School of Medicine at the University of Pennsylvania, aim to apply this knowledge to develop personalized approaches to treating diabetes and other metabolic disorders. The team published their findings this week in Cell.http://medicalxpress.com/news/2015-07-genetic-variation-response-anti-diabetic-drug.html
GeneticsThu, 02 Jul 2015 12:00:05 ESTnews355051144UAlberta creates DNA bank to unlock genetic clues about stutteringScientists at the University of Alberta's Institute for Stuttering Treatment and Research (ISTAR) want Albertans to give a spit—five millilitres to be precise—to help find the cause and a cure for stuttering.http://medicalxpress.com/news/2015-05-ualberta-dna-bank-genetic-clues.html
GeneticsWed, 20 May 2015 18:33:15 ESTnews351365587Genetic disposition most important factor for difference in school performancesWhy does one child learn easily, whereas another has difficulty keeping up at school? Why does the one child find it so difficult to remain sitting on a chair whereas another can work independently without any problems? Researcher Eveline de Zeeuw from VU University Amsterdam investigated the causes of differences in school performances and behaviour between primary school children. She discovered that the differences between children are largely caused by genetic disposition. On 24 March 2015 she defended her doctoral thesis about a twin study she did thanks to funding from NWO.http://medicalxpress.com/news/2015-04-genetic-disposition-important-factor-difference.html
Attention deficit disordersFri, 03 Apr 2015 07:36:24 ESTnews347265371Genetics: No evidence of role in racial mortality gapThere is still no evidence of genetic difference between blacks and whites to account for the health disparities in cardiovascular disease (CVD), according to a new study by McGill University researchers. Published in the American Journal of Epidemiology, the researchers suggest that after a decade of genetic studies, factors such as lifestyle, education and socio-economics - not genetics - are more promising avenues to understanding racial health disparities.http://medicalxpress.com/news/2015-03-genetics-evidence-role-racial-mortality.html
HealthMon, 16 Mar 2015 11:21:04 ESTnews345723655Study identifies genetic variation in cellular stressA new Cornell study examines how genetic differences among individuals impact cellular stress, a first step in understanding how this stress response relates to human diseases, such as diabetes.http://medicalxpress.com/news/2015-02-genetic-variation-cellular-stress.html
GeneticsThu, 05 Feb 2015 06:43:24 ESTnews342340996How well you sleep may depend on your genes, study suggests(HealthDay)—How much sleep you get each night may depend to some extent on your genes, a new study suggests.http://medicalxpress.com/news/2014-12-genes.html
Psychology & PsychiatryWed, 03 Dec 2014 14:30:01 ESTnews336837590Type 2 diabetes, cardiovascular disease may share deep roots(Medical Xpress)—Type 2 diabetes (T2D) and cardiovascular disease (CVD) appear to have a lot in common. They share risk factors such as obesity and they often occur together. If they also share the same genetic underpinings, then doctors could devise a way to treat them together too. With that hope in mind, scientists applied multiple layers of analysis to the genomics of more than 15,000 women. In a new study they report finding eight molecular pathways shared in both diseases as well as several "key driver" genes that appear to orchestrate the gene networks in which these pathways connect and interact.http://medicalxpress.com/news/2014-11-diabetes-cardiovascular-disease-deep-roots.html
GeneticsTue, 04 Nov 2014 12:21:50 ESTnews334326100Mexican genetics study reveals huge variation in ancestryIn the most comprehensive genetic study of the Mexican population to date, researchers from UC San Francisco and Stanford University, along with Mexico's National Institute of Genomic Medicine (INMEGEN), have identified tremendous genetic diversity, reflecting thousands of years of separation among local populations and shedding light on a range of confounding aspects of Latino health.http://medicalxpress.com/news/2014-06-mexican-genetics-reveals-huge-variation.html
GeneticsThu, 12 Jun 2014 14:00:07 ESTnews321787946Nature and nurture: Baby's development is affected by genes and conditions in the wombA recent study led by A*STAR's Singapore Institute for Clinical Sciences (SICS) found that genetics as well as the environment in the womb play important roles in the development of the baby. The effort by the international team of scientists and clinicians is the world's first attempt to discover how genetic and environmental factors affect the human epigenome . The results have fundamental implications for how epigenetic studies will be conducted in the future and for our understanding of how the mother's nutrition and lifestyle may have long-lasting effects on the health of her children.http://medicalxpress.com/news/2014-04-nature-nurture-baby-affected-genes.html
GeneticsMon, 28 Apr 2014 10:10:33 ESTnews317898623Scientists develop new approach to study how genetic variants affect gene expression(Medical Xpress)—Each individual carries a unique version of the human genome. Genetic differences can influence traits such as height, weight and vulnerability to disease, but precisely what these genetic variants are and how they exercise their impact is mostly unknown. UCLA researchers have now developed a novel approach to study the ways in which these individual differences affect how strongly certain genes are "expressed"—that is, how they are translated into the proteins that do the actual work in cells.http://medicalxpress.com/news/2014-01-scientists-approach-genetic-variants-affect.html
GeneticsFri, 10 Jan 2014 07:50:01 ESTnews308559633Study finds some people less susceptible to H7N9 influenza virus than others(Medical Xpress)—An international team of researchers working at the University of Melbourne in Australia has found that genetic differences in people result in different degrees of ability to fight the H7N9 influenza virus. In their paper published in Proceedings of the National Academy of Sciences, the team reports that their study of immune response observed in blood samples indicates that some people may be far better equipped to fight off the new flu strain than others.http://medicalxpress.com/news/2014-01-people-susceptible-h7n9-influenza-virus.html
Diseases, Conditions, SyndromesTue, 07 Jan 2014 10:10:01 ESTnews308311205Researchers discover link between expression of GATM and pain associated with statins(Medical Xpress)—A large team with members from several research institutions across the U.S. has found a possible link between the expression of the gene for glycine amidinotransferase (GATM) and pain experienced by patients who take statins to help lower their cholesterol levels. In their paper published in the journal Nature, the team describes their findings and what it might mean for patients in the near future.http://medicalxpress.com/news/2013-08-link-gatm-pain-statins.html
CardiologyThu, 29 Aug 2013 10:17:33 ESTnews296990222Multiple genes manage how people taste sweetenersGenetics may play a role in how people's taste receptors send signals, leading to a wide spectrum of taste preferences, according to Penn State food scientists. These varied, genetically influenced responses may mean that food and drink companies will need a range of artificial sweeteners to accommodate different consumer tastes.http://medicalxpress.com/news/2013-08-multiple-genes-people-sweeteners.html
GeneticsTue, 20 Aug 2013 13:44:41 ESTnews296225073Majority of toddlers who are overweight are still too heavy several years laterToddlers with extreme overweight are often still too heavy several years later. This is particularly true for children from families with a low socioeconomic status. They have a four times higher chance of developing chronic obesity than children from a better socioeconomic background. This is the conclusion psychologist Pauline Jansen. With the help of an NWO grant she did research for a period of one year at the Murdoch Children's Research Institute in Melbourne, Australia. Her research results were published on 23 July in the open access journal PLOS ONE.http://medicalxpress.com/news/2013-08-majority-toddlers-overweight-heavy-years.html
Overweight and ObesityTue, 06 Aug 2013 09:50:02 ESTnews295000238New findings could influence the development of therapies to treat dengue diseaseNew research into the fight against Dengue, an insect-borne tropical disease that infects up to 390 million people worldwide annually, may influence the development of anti-viral therapies that are effective against all four types of the virus.http://medicalxpress.com/news/2013-08-therapies-dengue-disease.html
Medical researchFri, 02 Aug 2013 14:18:21 ESTnews294671892Often misidentified, multiracial people value accurate perceptionsMultiracial people may be misidentified more often as being white than black and may value being accurately identified more so than single-race individuals, according to research presented at APA's 121st Annual Convention.http://medicalxpress.com/news/2013-08-misidentified-multiracial-people-accurate-perceptions.html
Psychology & PsychiatryFri, 02 Aug 2013 14:00:01 ESTnews294653769We each live in our own little world—smellwiseThere are some smells we all find revolting. But toward a handful of odors, different people display different sensitivities—some can smell them, while some can't, or some find them appealing, while others don't. A pair of studies appearing online on August 1 in the journal Current Biology now identifies the genetic differences that underpin the differences in smell sensitivity and perception in different individuals. The researchers tested nearly 200 people for their sensitivity for ten different chemical compounds that are commonly found in foods. They then searched through the subjects' genomes for areas of the DNA that differed between people who could smell a given compound and those who could not. This approach—known as a genome-wide association study—is widely used to identify genetic differences.http://medicalxpress.com/news/2013-08-worldsmellwise.html
GeneticsThu, 01 Aug 2013 12:00:01 ESTnews294575128