Texas Red® dye is a bright red-fluorescent dye with excitation ideally suited to the 561 or 594 nm laser lines. It is commonly conjugated to antibodies and proteins for cellular imaging applications.

Texas Red® sulfonyl chloride is susceptible to hydrolysis and its low solubility in water may complicate its conjugation to some biomolecules. To overcome this difficulty, we offer Texas Red®-X succinimidyl ester, which contains an additional seven-atom aminohexanoyl spacer ("X") between the fluorophore and its reactive group. Some conjugates are offered in the Texas Red®-X formulation.

For brighter conjugates and greater photostability, we offer a Texas Red® dye alternative—Alexa Fluor ® 594—as a reactive dye or conjugated to a variety of antibodies, peptides, proteins, tracers or amplification substrates optimized for cellular labeling and detection

Texas Red® (and Texas Red®-X) dye

Texas Red® dye is a traditional red-fluorescent dye that has been used extensively to label protein conjugates such as phalloidins for cytoskeleton counterstaining or antibody conjugates for immunofluorescence.

Phalloidin conjugates

Fluorescent conjugates of phalloidin using the Molecular Probes® Alexa Fluor® dyes are now the preferred F-actin stains for most applications across the full spectral range. The Alexa Fluor® phalloidin conjugates provide researchers with fluorescent probes that are designed to be superior in brightness and photostability to all other spectrally similar conjugates tested.

Dextran conjugates

Fluorescent conjugates of dextran using the Molecular Probes® Alexa Fluor® dyes are used for direct imaging of cell structures like neuronal projections or cell processes like endocytosis. The Alexa Fluor® dextran conjugates provide researchers with fluorescent probes that are designed to be superior in brightness and photostability to all other spectrally similar conjugates tested.

Resources

Molecular Probes® Handbook

The significantly revised 11th Edition is the most complete fluorescence labeling and detection reference available. The Molecular Probes® Handbook can help you achieve the best experimental results for your fluorescence labeling and detection experiments. View the handbook online or order your own copy.

Antifade reagents

Antifade reagents suppress photobleaching and preserve the signals of your fluorescently labeled target molecules. They offer excellent compatibility with Texas Red® dye and a multitude of dyes across the spectrum, making them especially valuable tools for multicolor applications.

Fluorescence SpectraViewer

Plot and compare spectra and check the spectral compatibility for common fluorophores including all the Molecular Probes® fluorescent probes. The Fluorescence SpectraViewer tool is formatted for both microscope imaging and flow cytometry applications.