IDT manufactures a complete range of high fidelity, DNA products for every synthetic biology application, from the highest quality oligonucleotides to complete cloned gene products. IDT also offers design tools and technical experts to help you easily order exactly what you need.

Synthetic biologists are fitting the genomes of microorganisms with synthetic gene circuits to break down polluting plastics, non-invasively diagnose and treat infections in the human gut, and generate chemicals and nutrition on long haul space flights. Although showing great promise in the laboratory, these technologies require control and safety measures that make sure the engineered microorganisms keep their functional gene circuits intact over many cell divisions, and that they are contained to the specific environments they are designed for.

From afar, the multistory fermenters — towering metal cylinders encompassed by scaffolding, ladders, and pipes — look like rockets on a launch pad. Climbing to the top of the fermenter, visitors to the Mexico City manufacturing plant can peer down at a set of paddles churning 50,000 liters of frothy, golden broth. Within the mixture, genetically engineered yeast are synthesizing lactones — a family of molecules responsible for the aromas of fruits and flowers. MIT Department of Biology alumna Emily Havens Greenhagen ’05 has visited the plant over several weeks to monitor her company’s most promising project: a plan to make perfume from yeast cells.

Industrial fertilizers help feed billions of people every year, but they remain beyond the reach of many of the world’s poorest farmers. Now, researchers have engineered microbes that, when added to soil, make fertilizer on demand, producing plants that grow 1.5 times larger than crops not exposed to the bugs or other synthetic fertilizers. The advance, reported here this week at a meeting of the American Chemical Society, could help farmers in the poorest parts of the world increase their crop yields and combat chronic malnutrition.

MIT associate professor Timothy Lu has devoted his career to coming up with novel ways to engineer cells, both bacterial and human, to perform new functions. Using this approach, he hopes to develop new therapies for a range of diseases, from cancer to drug-resistant infections.

We are entering the genomic age, as the distance between DNA/genomic research and consequential applications is rapidly shortening. From gene therapy to gene editing, powerful inventions for the betterment of humanity and the environment have never been more crucial.

In the era of social media and online tutorials, do-it-yourself (DIY) projects are more popular than ever. This trend is making its way into community laboratories, providing opportunities for the public to “do science” in ways that were previously within the exclusive realm of highly credentialed scientists and shrouded in the mystery of peer-reviewed journals.

The human body is made up of trillions of cells, microscopic computers that carry out complex behaviors according to the signals they receive from each other and their environment. Synthetic biologists engineer living cells to control how they behave by converting their genes into programmable circuits. A new study published by Assistant Professor Wilson Wong (BME) in Nature Biotechnology outlines a new simplified platform to target and program mammalian cells as genetic circuits, even complex ones, more quickly and efficiently.

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