I'm 26 years old. I found out i have hypo last Aug. I had a tsh of >160, I was very sick, all the hypo syptoms and an enlarged heart to top it off, I was full of water head to toe i lost 70 lbs since i have been taking meds. In Nov. of last year i started to have joint pains, My knee's are the biggest problem, also my elbows, hands, feet and back. I also feel like crap. With all the pain i have been having i felt better when i was sick with hypo, now instead of sleeping all the time, i lay around in pain or am working in alot of pain. Sometimes my knee's or elbows snap and hurt very badly. It's very hard to handle each day, I'm going to have to stop working soon, I can't handle it anymore. I have been to a interenst, Who thought i might have gout, Or Lupus. But the blood test for lupus came back neg, and gout is kinda dumb considering my age and how long it's been going on+useually it's only on joint at a time. I was refered to a Orthapedic sergon, we did mri on left knee, he says torn medial menicus or what ever it's called. Told me i need to be more active . Then i went to a dermatoligst she took a skin biospy from my back. I have a big red rash thats been there for around four years. I also went to a Rhematoligist she did more blood tests including an mri of my right knee-everything came back ok. So I'm sure i can throw the idea of a torn cart in my left knee out the window, cause i have the same pain in both knee's and right's mri came back fine. i have been pushing the idea of Lupus, and Lyme dieases with all the doctors, The only reason i think i might have lyme is cause i work 40+ hours outdoors in fields and the woods here in MI. The seem to say ok i'll test you for that and the blood tests come back neg. I know the test are not very good at telling us what is going on. Then i got refered to a gastrontoligist he's testing me for celiac dieases witch also makes alot of scince because i has most of the list of symptoms. It's been a very hard 7 months, If any one has any ideas or anything we might be over looking. Please let me know!!

Also - Lyme disease sometimes shows up as negative on the tests if it has been a while since the initial infection, but it will make you sicker and sicker and end up causing neurological problems if you don't get treated.

A few thoughts:
- celiac disease is very possible. I would definitely follow through with that testing. Usually they do a blood test called an anti-ttg or an anti-endomysial antibody, followed by an intestinal biopsy (easier than it sounds) if the test is positive. I recently ran across some very interesting research, though, that says in cases of psoriasis and psoriatic arthritis, people who test positive for anti-gliadin antibodies (an older, less specific and less reliable test for celiac disease) benefitted from a gluten-free diet (their arthritis and psoriasis improved) even if they tested NEGATIVE for all the confirmatory tests for celiac disease. People with thyroid disease have an increased chance of having celiac disease, and vice versa.

- I've seen some interesting work on using T3 (Cytomel) to treat people with fibromyalgia - perhaps it might help with the joint inflammation too? I got in trouble for something I posted, not sure what, so i don't want to give you the reference, but you could google it.

- I did once, in my ramblings, come across some medical papers reporting on cases of x-ray proven arthritis that resolved with treatment for hypothyroidism, so there is some precedent for the hypothyroidism itself to affect the joints - what is your current thyroid dose and what do your thyroid lab tests look like now? Could you be under-medicated?

Thanks for the replies, As for lyme i know the test are about useless,. And i never have a fever that i know of. I'm going to find a endo or just a good doc to help with the thyroid issue, I can only remember the tsh from my last too tests, jan was 5.0 and april it was 3.3. I'm taking 200mcg's. i don't think this is thyroid related as i NEVER had pain when my tsh was over 160 for a long time. And i think something cause hypo, celiac would make alot of since, i have like 12 of the symptoms of it, i took the blood test on tuesday,. I keep telling my docs there's a reason i'm hypo something caused it, i have something else, it's very rare for some one of my sex and age to get it.