<p>Law enforcement shut down U.S. 421 shortly before 5 p.m. Wednesday after a two-car crash outside the truck stop near the Isabel Holmes Bridge. </p><p>New Hanover County dispatch said an ambulance was sent to the scene but it was not clear what kind of injuries there were. </p><p>Earlier Wednesday, a two-car crash was blocking the left outbound lane of the Cape Fear Memorial Bridge shortly after 4 p.m.</p><p>A sheriff's deputy at the scene said there were no injuries.</p><p>Traffic was backed up into Wilmington as a result of that crash.</p><p><i></p><p>Check back later for more on this developing story.</p><p>- <a href="http://www.starnewsonline.com/section/topic9904"><b>Brian Freskos</b></a></i></p>