Congrats @Minib a positive is a positive! Just remain positive now at it continues to rise nicely. I know exactly what it's like to worry.

AFM, I have some mixed news. Had my 6 week BT today and whilst HCG is continuing to rise nicely now 33,910, progesterone has dropped again from 104 a week ago to 64. That's a swing from 138 two weeks ago to 64 today. I am so scared its a sign things are heading south. So after FN told me yet again there was nothing to worry about, I rang my FS pager and he called me back. He wasn't that happy I rang and thinks I'm over reacting but has agreed to put me on crinone finally after having a non medicated cycle from the beginning. He thinks my levels are still normal and is not saying much about the drop claiming they fluctuate, but as far as I'm concerned they are not fluctuating they are dropping. He said if I go on it now, I'll need to stay on it until end of first trimester. He thinks I really don't need it but for peace of mind go on it. I don't know. Do I trust my body to do things naturally or take the crinone and potentially prolong the inevitable. He said he doesn't read much into progesterone as long as HCG is increasing nicely which it is. I said I would feel better taking it and so he left a script for me and I just picked up the crinone. What should I do? Should I have reason to panic? Would love your thoughts.

That progesterone level is totally nothing to worry about. Mine did the same thing, got down to 47.

The problem is you're comparing yourself to other ivf women on here who are loaded up with progesterone supplements and have really high numbers - way higher than it would be naturally. In the first six weeks or so the average natural level is like 27.

Also, progesterone has been shown in studies to go up and down during the day. So a BT in the morning might have a different level to the evening.

See the pic below, for natural pregnancy at six weeks the average is 25 up to about 45. So your progesterone is high, not low.

Your FS sounds a bit mean though he could have given you some more info to help you understand.

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IVF/FET in January/February 2015 #2

Originally Posted by ScubaGal

That progesterone level is totally nothing to worry about. Mine did the same thing, got down to 47.

The problem is you're comparing yourself to other ivf women on here who are loaded up with progesterone supplements and have really high numbers - way higher than it would be naturally. In the first six weeks or so the average natural level is like 27.

Also, progesterone has been shown in studies to go up and down during the day. So a BT in the morning might have a different level to the evening.

See the pic below, for natural pregnancy at six weeks the average is 25 up to about 45. So your progesterone is high, not low.

Your FS sounds a bit mean though he could have given you some more info to help you understand.

Oh that is such a huge relief to hear. Thank you ScubaGal. It is hard being a natural cycle and not knowing if I am tracking well or not. With HCG going up nicely it did seem confusing that progesterone was dropping. I was just shocked to hear how far it had dropped. I decided to start using the crinone over night as agreed with the specialist so it will probably make it difficult to know from here if it naturally would have gone back up or if it's the crinone but right now it's psychologically giving me the support I need and if it means it supports the embryo than I am happy. Did you end up going on support when it dropped to 47 or did you just ride it out?

It was fine. At this point viability isn't about HCG or progesterone it's about your scans anyway.

My pregnancy is a natural cycle too. Don't worry about freaking out though, its pretty natural when you've been through IVF. Just try to practice listening to your doctors and midwives, don't compare yourself to other women with IVF and challenging histories and step away from the google.

You'll find there are different things to freak out about all the way through so it's a good idea to start some evening meditation and relaxation practice to help you cope.

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Ok. Good point. I appreciate your frankness ScubaGal. For us our journey has been heightened by the need to use donor sperm (known older donor sperm) so the stakes are high here for us and every set back feels like it will all come crashing down. Just fear and anxiety but after hearing from you and now reflecting on the conversation with FS I maybe over reacted. I will discuss coming off it again once we have the scan next week. That's what he said anyway. I don't know whether you can come on or come off it though. You obviously did the same as me? Did a natural cycle and then went on it and then off?

Oh that is such a huge relief to hear. Thank you ScubaGal. It is hard being a natural cycle and not knowing if I am tracking well or not. With HCG going up nicely it did seem confusing that progesterone was dropping. I was just shocked to hear how far it had dropped. I decided to start using the crinone over night as agreed with the specialist so it will probably make it difficult to know from here if it naturally would have gone back up or if it's the crinone but right now it's psychologically giving me the support I need and if it means it supports the embryo than I am happy. Did you end up going on support when it dropped to 47 or did you just ride it out?

The other thing that's interesting is if you were a regular Preggo chick not an ivf'er and you went to your GP for your antenatal care, they wouldn't even test your progesterone level. Like at all, so you'd never even know.

That's how rare actual progesterone deficiency is, and there isn't even a strong link in the data to show higher progesterone helps a pregnancy.

Most women who fall pregnant naturally just pee on one stick and from there hey presto they are pregnant. It's hard to switch into that kind of thinking but I find its a good yardstick - just think of all the women that get no antenatal care at all and go on to deliver healthy babies.

That's true because my GP said he never tested P4 before. I think maybe I should have listened to them when they said it was fine..... Can you go on and off again? Maybe I should call him again and say ok I'll trust him?! He'll think I'm a psycho! I think I am partially becoming one!! 😊

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