Circling back to the topic of how precision medicine-oriented data can best serve public health interest, JNCI recently ran a commentary and primary research article on BRCA1 and BRCA2 screening in the context of public health interests in the Ashkenazi population (jnci.oxfordjournals.org/conten...). Would something like this -- whether BRCA testing or otherwise -- be implementable or cost-effective in the US? How could precision medicine inform these efforts?