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Cushing's Disease in Cats

Hyperadrenocorticism in Cats

Cushing’s syndrome (hyperadrenocorticism) occurs when the adrenal gland produces too much cortisol. While cortisol is an essential hormone, elevated levels lead to illness. There are several possible causes to this disease, including a tumor in the pituitary gland or the outer layer of the adrenal gland. Although the disease is rare in cats, it is more likely to affect middle-aged or older cats and females more than males. Breed, however, does not seem to be a determining factor. In addition, diabetes almost always accompanies the ailment.

Symptoms

Excessive urination (polyuria)

Excessive thirst (polydipsia)

Excessive eating (polyphagia)

Weight loss or gain

Enlarged liver (hepatomegaly)

Fragile skin

Symmetrical hair loss

Diarrhea

Vomiting

Enlargement of the abdomen

Curled ear tips

Unkempt appearance

Weakness (lethargy)

Changes in sexual behavior

Causes

Tumor in the pituitary gland

Tumor in an adrenal gland

Age of the cat

Diagnosis

The tests listed below may be used to determine the underlying cause of your pet's disease:

polydipsia

polyphagia

polyuria

pituitary gland

The gland that is found at the bottom of the brain whose job is to maintain appropriate levels of hormones in the blood

lethargy

The condition of being drowsy, listless, or weak

hepatomegaly

An enlargement of the liver to an abnormal size

insulin

A hormone created by the pancreas that helps to regulate the flow of glucose

adrenal gland

The gland that produces the hormone adrenaline and others; helps to regulate the metabolism, electrolytes, and even sexual function; also helps to regulate the way the body responds to injury, trauma, etc. The adrenal gland is found near the kidney. Also referred to as the suprarenal gland.