Another angel came out of the temple in heaven, and he too had a sharp sickle. 18 Still another angel, who had charge of the fire, came from the altar and called in a loud voice to him who had the sharp sickle, “Take your sharp sickle and gather the clusters of grapes from the earth’s vine, because its grapes are ripe.” 19The angel swung his sickle on the earth, gathered its grapes and threw them into the great winepress of God’s wrath. 20 They were trampled in the winepress outside the city, and blood flowed out of the press, rising as high as the horses’ bridles for a distance of 1,600 stadia. (Revelation 14:17-20 NIV).

Here we see God’s anger which will be poured out on the unbelievers who will attack the Holy city, Jerusalem. In one of my previous posts I mentioned that the harvest pictured here (verses 14-16) is a harvest of human souls. Now, “grapes” are being pictured here, symbolizing that God’s wrath is finally “ripe.” It is time to tolerate no more evil and to punish the world for not accepting God’s peace offer. When these “grapes” are thrown into the wine press of God’s wrath, the result will be destruction to such an extent that the blood of God’s enemies will flow for 1,600 stadia, or the equivalent of 180 miles. This will literally take place at the battle of armeggedon. It will happen “outside the city” i.e. Jerusalem. The blood will probably flow 180 miles from the valley of Jehoshaphat down the Jordan valley into the Dead Sea. Lots of people will die

Here are some other passages that describe the scene of destruction:

“I have trodden the winepress alone;
from the nations no one was with me.
I trampled them in my anger
and trod them down in my wrath;
their blood spattered my garments,
and I stained all my clothing.4 It was for me the day of vengeance;
the year for me to redeem had come.5 I looked, but there was no one to help,
I was appalled that no one gave support;
so my own arm achieved salvation for me,
and my own wrath sustained me.6 I trampled the nations in my anger;
in my wrath I made them drunk
and poured their blood on the ground.” (Isaiah 63:3-6)

I will gather all the nations to Jerusalem to fight against it; the city will be captured, the houses ransacked, and the women raped. Half of the city will go into exile, but the rest of the people will not be taken from the city. 3 Then the Lord will go out and fight against those nations, as he fights on a day of battle. 4 On that day his feet will stand on the Mount of Olives, east of Jerusalem, and the Mount of Olives will be split in two from east to west, forming a great valley, with half of the mountain moving north and half moving south. 5 You will flee by my mountain valley, for it will extend to Azel. You will flee as you fled from the earthquake[a] in the days of Uzziah king of Judah. Then theLord my God will come, and all the holy ones with him… This is the plague with which the Lord will strike all the nations that fought against Jerusalem: Their flesh will rot while they are still standing on their feet, their eyes will rot in their sockets, and their tongues will rot in their mouths. 13 On that day people will be stricken by the Lord with great panic. They will seize each other by the hand and attack one another. 14 Judah too will fight at Jerusalem. The wealth of all the surrounding nations will be collected—great quantities of gold and silver and clothing. 15 A similar plague will strike the horses and mules, the camels and donkeys, and all the animals in those camps. (14:.2-5, 12-15 NIV)