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This is the accepted version of the following article: Robertson, C, Ramsay, C, Gurung, T, Mowatt, G, Pickard , R & Sharma, P 2014, 'Practicalities of using a modified version of the Cochrane Collaboration risk of bias tool for randomised and non-randomised study designs applied in a health technology assessment setting.' Research Synthesis Methods, vol 5, no. 3, pp. 200-211., which has been published in final form at 10.1002/jrsm.1102