In contrast, if an animal performs retaliation behavior it is challenging the dominance of an animal performing a threat. The resulting escalated aggression is also terminated by flight and submissive behavior. However the meaning is quite different - indicating which mouse has lost the particular fight, not necessarily which mouse is dominant in a stable uncontested hierarchy.

Fleeing and withdrawal can also occur in response to any threatening stimulus, be it social, predatory (e.g. when mice flee from human handlers), or abiotic (e.g. when mice withdraw from a brightly lit open space). Fleeing and withdrawal are viewed as evidence of aversion, anxiety, and/or fear.