T2-weighted MRI and DTI were performed in the white
matter of five healthy volunteers. Fractional anisotropy (FA), radial and axial
diffusivity were computed in 4 brain regions. Using T2 MRI, texture spectral
similarity that dictates inter-voxel relationships was computed based on
polar Stockwell transform. The genu and splenium of the corpus callosum
demonstrated greater FA, axial diffusivity, and texture dissimilarity than
the other structures, opposite to the pattern of radial diffusivity. With
equivalent power to DTI indices, texture spectral similarity may be a
sensitive measure of white matter architecture based on conventional MRI and
embedded into clinical practice.