Hulu’s Locke And KeyTV series is gearing up for production, with IT‘s Andy Muschietti confirmed to direct the pilot episode (replacing the very busy Scott Derrickson), and it’s finally cast its first actor for the adaptation of Joe Hill and Gabriel Rodriguez’s brilliant comic.

THR reports that Frances O’Connor has signed on to star as “Nina Locke, the mother of the three siblings who moves the family to Maine after her husband’s slaying.” O’Connor was recently seen as matriarch Peggy Hudson in James Wan’s The Conjuring 2, and she’s taking the role that was played by Annabelle: Creation‘s Miranda Otto in the 2011 Fox pilot, proving that the reach of the Waniverse knows no bounds.

O’Connor has also starred in the TV series Cleverman, AI: Artificial Intelligence and the first series of The Missing.

Hill is writing the script for the pilot with Lost and Bates Motel‘s Carlton Cuse, who’ll be acting as showrunner should the show go to series. Muschietti and his producing partner and sister Barbara will executive produce, alongside Cuse, Hill and IDW’s David Ozer. It’s “a horror/fantasy series that revolves around three siblings who, after the gruesome murder of their father, move to their ancestral home in Maine only to find the house has magical keys that give them a vast array of powers. Little do they know, a devious demon also wants the keys, and will stop at nothing to attain them.”

Ozer said, “We are thrilled to have the multidimensional talents of Frances O’Connor to breathe color and life into this pivotal character in our series, and along with a stellar production team in place, we have no doubt that we will be able to bring Joe Hill’s creative vision to the small screen.”

We’ve been waiting a long, long time for this one and we can’t wait to see what else the casting department has in store for us. Hulu had better pick this one up to series…