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The Sahlgrenska Hospital was founded in 1772 following a donation by Niclas Sahlgren. The current hospital was formed in 1997 by integrating three hospitals: Sahlgrenska Sjukhuset, Östra sjukhuset, and Mölndals sjukhus. The Sahlgrenska University Hospital has been operated by the Västra Götaland Regional Council since its formation in 1999.[2]

On 24 June 2009, a 24,000 m2 (260,000 sq ft) new facility with 312 beds was officially opened. The new facility will enable rebuilding and renovation of older facilities at Sahlgrenska. The facility also features nephrology centre, dialysis, transplantation centre, stroke unit, hematology, and wards for medicine and surgery.

Sahlgrenska Academy is the University of Gothenburg's faculty of education and research in health sciences. It operates in close conjunction with the university hospital. The academy was formed the 1st of July 2001 by combining the three previous faculties for medicine, odontology and health sciences.[3]