Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Applications

Approved:

Western blot

Immunoprecipitation (1:1000 - 1:2000)

ELISA (1:1000 - 1:5000)

Specificity and Use

Immunogen:

PBP2a recombinant protein derived from MRSA bacteria

Specificity:

Specifically detects PBP2a from MRSA. Has the ability to distinguish both MRSA and MSSA in tested assays; it did not show any binding signal for bacterial cell lysates from MSSA. This antibody showed no cross-reactivity with other tested bacterial proteins.