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HELKOSS uses: Ranitidine is used to treat ulcers; gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and injury of the food pipe (esophagus); and conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome. Over-the-counter ranitidine is used to prevent and treat symptoms of heartburn associated with acid indigestion and sour stomach. Ranitidine is in a class of medications called H2 blockers. It decreases the amount of acid made in the stomach.Ranitidine comes as a tablet, an effervescent tablet, effervescent granules, and a syrup to take by mouth. It is usually taken once a day at bedtime or two to four times a day. Over-the-counter ranitidine comes as a tablet to take by mouth. It is usually taken once or twice a day. To prevent symptoms, it is taken 30-60 minutes before eating or drinking foods that cause heartburn. Follow the directions on your prescription or the package label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take ranitidine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.Dissolve ranitidine effervescent tablets and granules in a full glass (6-8 ounces) of water before drinking.Do not take over-the-counter ranitidine for longer than 2 weeks unless your doctor tells you to. If symptoms of heartburn, acid indigestion, or sour stomach last longer than 2 weeks, stop taking ranitidine and call your doctor.Ranitidine may be added to an intravenous fluid that will drip through a needle or catheter placed in your vein for 15-20 minutes, one to four times a day. It also may be added to your total parenteral nutrition (TPN) solution.Ranitidine decreases acid in your stomach to help treat an ulcer or prevent one from developing. Ranitidine helps to decrease the stomach pain, diarrhea, and loss of appetite that ulcers can cause. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.