The use of electronic response pads or “clickers” is a popular way to engage students and create an active-learning environment, especially within large chemistry courses. The authors of this paper examined students’ perceptions of how the clicker affected their learning, participation, and engagement in the classroom, as well as their overall experience within a first-semester general chemistry course at a liberal arts institution. Overall, students perceived that clickers provided a significant enhancement to their learning, with women valuing the technology to a greater extent.