In January 2015, Simmons was cast in a leading role in the upcoming film Kong: Skull Island,[15] though he and Michael Keaton later exited the film.[16] Simmons performed a substantial number of voice-over roles alongside his live action work. Several of these have arisen from his J. Jonah Jameson character in Raimi's Spider-Man films, including voices of two newspaper editors in episodes of the eighteenth season of The Simpsons. While unnamed, these characters are clearly meant to emulate Jameson (one, bearing Jameson's appearance, demands "pictures of Spider-Man," then one being reminded he works at a poetry journal, and so demands "poems about Spider-Man").[original research?] Likewise, Simmons voiced an editor-in-chief of a newspaper (with Jameson's appearance and mannerisms) for a 2013 episode of The Hub'sPound Puppies. In 2016, Simmons lent his voice to two animated films, voicing the antagonist Kai in Kung Fu Panda 3 and Mayor Lionheart in Zootopia. Worlds Apart is a 2015 Greek drama film directed by Christoforos Papakaliatis. Worlds Apart consists of three separate narratives, each following a love story between a foreigner and a Greek. Each story represents a different generation falling in love during a time of socioeconomic turmoil that dominates Southern Europe as a whole, only to connect as a single story in the end. Simmons stars as Sebastian.

In the field of television commercials, Simmons is featured as Professor Nathaniel Burke of the University of Farmers in ads for Farmers Insurance Group, since 2010.[20]

Video games

Simmons appears as the anti-communist U.S. President Howard T. Ackerman in the video game Command & Conquer: Red Alert 3 and for a series of promotional advertisements parodying the 2008 presidential elections. In these advertisements, he offers himself (as Ackerman) as an alternative to other, unnamed presidential candidates and uses the slogan "Vote for me, if you want to live."[21]