It was a rare autoimmune disease. He was straight man who was funny, and wrote or directed some of my favorite movies. Most people my age can quote most of them. Sad. Seems like he was a nice guy too. He will be missed.

I know that a large part of my sense of humor developed and revolved around many of his movies. I will not flip past Groundhog Day – EVER. If it's on, I'm watching it. I remember the first time I saw Stripes as a kid – it was a comedy revelation to me.

NOOOOOOOOOOOOOOOOOOOOOOOOOOOO!! Harold Ramis was, like Senor Salty said, a COMEDIC GENIUS!! He will be truly missed. Thank you Harold for sharing your talent with the rest of the world, and we are all the better for it. RIP. /wipes away tears

My brother and I are huge fans and we're really mourning. That autoimmune shit fucking sucks, mostly because you pretty much can't get rid of it (although you CAN maybe go into remission, depending on which one of dozens of lovely autoimmune disorders you get to have).

Eh, diseases suck. I'm very pissed off about diseases that can't be "fixed" lately. I know that's a Captain Obvious remark, but losing my grandma last fall and getting ready to lose my cat makes me kind of a melancholy misantropic bitch. Sorry.

Anyway, Mr. Harold Ramis…he went to Wash U here in my neck of the woods. That has nothing to do with anything except that every time I'm in that neighborhood, I say, "Harold Ramis went there!"

At our 1982 wedding, when the priest said we are now going to exchange vows, my husband did the "duh duh duh" just like Bill Murray did to Harold Ramis in Stripes when they signed up for the Army. We were both cracking up and the priest didn't know what was going on.

He had autoimmune vasculitis, where the white blood cells start attacking the walls of your blood vessels. He had been in remission but it came back.

I had the pleasure of being able to watch a very talented Harold Ramis doing SCTV and the early days of all the great comedians that came out of that show like John Candy, Martin Short, Joe Flaherty, Dave Thomas, Andrea Martin, Catherine O'Hara, Eugene Levy, Rick Moranis. SCTV had to be the inspiration for SNL but man these guys delivered more constantly funny stuff every week with next to nothing budgets.

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