NEWARK, N.J. (AP) - U.S. Sen. Bob Menendez "sold his office for a lifestyle he couldn't afford" by accepting luxury trips from a wealthy doctor seeking political influence in return, a government prosecutor told jurors Wednesday during opening statements of the Democrat's corruption trial.

Menendez, New Jersey's senior U.S. senator, later lied about the trips on Senate disclosure forms, Justice Department attorney Peter Koski said as he laid out the government's case against Menendez and the doctor, Florida ophthalmologist Salomon Melgen.

The two were indicted in 2015 and face multiple fraud and bribery charges in a case that could threaten Menendez's political career and potentially the makeup of a deeply divided U.S. Senate if he's convicted.

Both men have pleaded not guilty. Menendez said before entering the courthouse Wednesday: "Not once have I dishonored my public office."

Defense attorneys were scheduled to give their opening statements later Wednesday.

Koski described Menendez pressuring government officials to help Melgen with securing visas for his foreign girlfriends, a lucrative port security contract in the Dominican Republic and a multimillion-dollar Medicare dispute. Individually and through his company, Melgen also contributed hundreds of thousands of dollars to Menendez's legal defense fund and entities that supported his re-election.

"He went to bat when Dr. Melgen asked, and Dr. Melgen asked frequently," said Koski, who discounted defense lawyers' contention in court filings that the trips were innocent gifts between friends. "There's no friendship exception to bribery. There's no friendship exception to breaking the law."

Defense lawyers say that the trips were examples of friends vacationing together, that most of Melgen's contributions went to committees Menendez didn't control and that he didn't control the people he lobbied on Melgen's behalf.

Flanked by his two adult children and at times choking back tears, Menendez said outside court Wednesday: "I started my public career fighting corruption - that's how I started - and I have always acted in accordance with the law.

"And I believe when all the facts are known, I will be vindicated," Menendez said.

Menendez is up for re-election next year. If he is convicted and steps down or is forced out of the Senate by a two-thirds majority vote before Gov. Chris Christie leaves office Jan. 16, the Republican governor would pick a successor. A Democrat has a large polling and financial advantage in November's election to replace Christie.

Menendez said he plans to be at the trial daily but will decide whether to return to Washington to cast votes in the Senate based on the issue and whether his vote could make a difference. The judge last week ruled against an attempt by Menendez to pause the trial on days when important Senate votes were scheduled.

Republican Ted Stevens of Alaska was the last sitting U.S. senator to go on trial. His conviction was overturned after a Justice Department investigation concluded prosecutors had committed misconduct.

Democrats in New Jersey, including junior U.S. Sen. Cory Booker, have stood by Menendez. Booker was in court on Wednesday to support him.

Among the gifts prosecutors say Melgen gave Menendez were flights on Melgen's private jet, vacations at Melgen's private villa in the Dominican Republic frequented by celebrities like Beyonce and Jay Z, and a three-night stay at a luxury Paris hotel valued at nearly $5,000.

Melgen also directed more than $750,000 in campaign contributions to entities that supported Menendez, according to the indictment, which alleges they were inducements to get Menendez to use his influence on Melgen's behalf.

Prosecutors say that lobbying included a three-year effort to help Melgen avoid paying $8.9 million for overbilling Medicare, a meeting with an assistant secretary of state to help Melgen in a contract dispute over port screening equipment in the Dominican Republic, and helping one of Melgen's girlfriends and her sister get into the country after their visas were denied.

Melgen's sentencing in a separate Medicare fraud case has been delayed until after his trial with Menendez.

Jurors will have to wade through complex legal concepts, including whether Menendez's interactions with executive branch officials were "official acts" as defined under federal bribery statutes. That will depend on how a 2016 U.S. Supreme Court decision reversing the bribery conviction of former Virginia Gov. Bob McDonnell, a Republican, is interpreted.

Along with picking three more jurors needed before opening statements could begin Wednesday, the morning featured some sparring between attorneys for Menendez and Judge William Walls.

Attorney Ray Brown accused Walls of disparaging Menendez in his opinion denying Menendez's motion to postpone the trial on days of important Senate votes. Walls continually interrupted to deny the allegation.

Walls chided defense attorneys for filing a motion on what to include in jury instructions at the end of the trial.

When attorney Abbe Lowell pointed out that the motion was filed according to the judge's order from December, Walls replied, "Fine. Bill me."

(AP Photo/Ahn Young-joon, File) FILE - In this Aug. 10, 2017, file photo, a man watches a television screen showing U.S. President Donald Trump and North Korean leader Kim Jong Un during a news program at the Seoul Train Station in Seoul, South Korea.

The Trump administration said Monday it's not seeking to overthrow North Korea's government after the president tweeted that Kim Jong Un "won't be around much longer."

The Trump administration said Monday it's not seeking to overthrow North Korea's government after the president tweeted that Kim Jong Un "won't be around much longer."

(AP Photo/Evan Vucci) President Donald Trump listens during a luncheon with South Korean President Moon Jae-in and Japanese Prime Minister Shinzo Abe, at the Palace Hotel during the United Nations General Assembly, Thursday, Sept. 21, 2017, in New York.

President Donald Trump has added economic action to his fiery military threats against North Korea, authorizing stiffer new sanctions in response to the Koreans’ nuclear weapons advances.

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The trial of Democratic U.S. Sen. Bob Menendez has entered its third week, and some political experts say that it is causing some turmoil for some of New Jersey’s Democrats as the state’s gubernatorial election draws near.

The trial of Democratic U.S. Sen. Bob Menendez has entered its third week, and some political experts say that it is causing some turmoil for some of New Jersey’s Democrats as the state’s gubernatorial election draws near.

(AP Photo/Evan Vucci) Rep. Richard Neal, D-Mass., left, and Rep. Kevin Brady, R-Texas, right, listen as President Donald Trump speaks during a meeting with members of the House Ways and Means committee in the Roosevelt Room of the White House, Tuesday, Se