In April 2000 the party was re-established as the Democratic Party of Moldova (PDM).[8] The PDM received 5% of the vote in the 2001 parliamentary election, but failed to win a seat. The party then joined the Democratic Moldova Electoral Bloc for the 2005 election; the Bloc received 28.4% of the vote, winning 34 seats, of which eight were taken by the Democratic Party. However, after the elections the three constituent parties Bloc split into separate parliamentary groups.

In the 2010 parliamentary election, the PDM received 12.7% of the vote and 15 seats, continuing to govern as a component party of the Alliance for European Integration coalition. However, the coalition lost a vote of no confidence on 13 February 2013, leading to the creation of the Pro-European Coalition in May 2013, which also included the PDM, as well as the PLDM and Liberal Reformist Party (PLR), a splinter from the PL.