Product details

Product details

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Immunogen

Synthetic peptide

Specificity

The synthetic peptide sequence used to generate the antibody AP6920b was selected from the C-term region of human VCP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Target details

Target details

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Alternative Name

VCP

Background

VCP is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.