For the Consumer

Along with its needed effects, tobramycin ophthalmic (the active ingredient contained in Tobrex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking tobramycin ophthalmic:

Less Common

Itching, redness, swelling, or other sign of eye or eyelid irritation not present before use of this medicine

Symptoms of Overdose

Increased watering of the eyes

itching, redness, or swelling of the eyes or eyelids

painful irritation of the clear front part of the eye

Some side effects of tobramycin ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less Common

Burning or stinging of the eyes

Eye ointments usually cause your vision to blur for a few minutes after application.

For Healthcare Professionals

Ocular

Ocular side effects of tobramycin ophthalmic (the active ingredient contained in Tobrex) include eyelid itching and swelling. Conjunctival erythema has also been reported.[Ref]

Hypersensitivity

A case of allergic conjunctivitis and blepharitis associated with tobramycin ophthalmic (the active ingredient contained in Tobrex) ointment has been reported. Hypersensitivity was confirmed by patch testing.[Ref]

Tobramycin ophthalmic has been associated with hypersensitivity reactions.[Ref]