Hope and help for triple-negative (TNBC) and other forms of hormone-negative breast cancer.

Monday, August 4, 2014

Anti-inflammatory drugs could treat TNBC

Some triple-negative breast cancer tumors may benefit from JAK
inhibitors, a class of anti-inflammatory drugs currently used to treat rheumatoid
arthritis, according to research in Cell Reports.

These tumors rely on an antiviral pathway related to inflammation,
widely recognized for roles in cancer, rheumatoid arthritis, and other
inflammatory diseases. Biologically, they have mutations of the proteins p53
and ARF.

"There are JAK inhibitors in use for rheumatoid arthritis
and being tested against a number of other conditions," said senior author Jason D. Weber, PhD, of the Washington University School of Medicine in St. Louis, Missouri

2 comments:

I'd check with Washington University, where this research was done. They might know of studies in the pipeline. Also, Breastcancer.org has a list of clinical trials at https://www.breastcancertrials.org/bct_nation/browse_trials.seam. And I have a link to news on clinical trials on this blog--look in the right hand column.

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Surviving Triple-Negative Breast Cancer: Hope, Treatment, Recovery

Finally! A book about TNBC written by a woman who's been through it—Patricia Prijatel, founder and editor of this blog. If you like this blog, you'll love this book.

Patricia Prijatel

Founder of Positives About Negative and author of Surviving Triple Negative Breast Cancer

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From Symphony Sisterhood

Welcome

When I was diagnosed with hormone-receptor-negative breast cancer, I required a positive attitude of myself—I was not going to let a disease have the upper hand. I hope I can share some at that attitude with you while I offer what I have learned in my trek through this disease as a patient and medical writer.

It's a given that life ends in death. Cancer just makes you face that inevitability more directly than you might have before. To me, that means living fully right now.

Three Mountain Dogs, a children's book by Patricia Prijatel

Triple-negative breast cancer (TNBC) lacks hormone receptors for estrogen, progesterone, and Her2/neu. It affects about 20 percent of all those with breast cancer. This blog offers information and hope for those with TNBC and other forms of hormone-negative breast cancer.

Calm Spirit Note Cards

Blank greeting cards with the Calm Spirit image are available in packets of 6. They're ideal for sending a personal message of encouragement to anyone living with cancer. Boxes of six are available for $10.00 and can be ordered by contacting my friend Madlyn at madlyn.ferraro@ gmail com. Individual cards are $2.50 each.