Matthew Stafford threw for two touchdowns, rookie Jamal Agnew broke the game open with an 88-yard punt return in the fourth quarter and the Detroit Lions beat the New York Giants 24-10 on Monday night.

The Lions (2-0) sacked Eli Manning five times and Stafford put together another big game while sending the Giants (0-2) to a second straight disappointing performance in a season where so much was expected. Star receiver Odell Beckham Jr returned from a sprained left ankle, but New York still struggled offensively.

Stafford found Marvin Jones for a 27-yard touchdown in the first quarter and passed to Eric Ebron for a go-ahead seven-yarder in the second. Matt Prater added a 56-yard field goal just before halftime that bounced off and over the upright, helping the Lions to a 17-7 lead at the break.

Ezekiel Ansah had three sacks as Detroit joined Atlanta and Carolina as the only unbeaten teams in the NFC through Week 2.

Beckham, a three-time Pro Bowler who missed the season opener, had four catches for 36 yards in limited action.

Manning threw an 18-yard touchdown pass to Evan Engram on the first play of the second quarter, but the rookie tight end was called for unsportsmanlike conduct for a seemingly obscene gesture. It allowed the Lions to get the ball at the Giants 45 after the kickoff went out of bounds and Stafford drove them for a second score.

New York closed to 17-10 on Aldrick Rosas’ 25-yard field goal early in the second half, but it wasted a chance for a TD. The Giants had first-and-goal at the 1 and then got pushed back to the 11 on a holding penalty on a first-down run.

Agnew then helped clinch the game for Detroit with his big return with 12:56 left, faking out New York punter Brad Wing on his way to the end zone. It was the fifth-longest punt return in team history.