*Drug of choice in emergency lowering of intraocular pressure (glaucoma)

Neostigmine(Prostigmin) & Physostigmine(Generics)

Class: Indirect-Acting Cholinergic Agonist

MOA: Stimulate muscarinic and nicotinic sites

Therapeutic Uses: Stimulation of the bladder and GI tract. Antidotes for overdoses of anticholinergic drugs like Atropine, antipsychotic drugs, antidepressants, tubocurarine. Treatment of Myasthenia gravis(deterioration of Nmreceptors at the neuromuscular