Thousands of people have fled their homes since the fires broke out on Monday.

Estimated at 50 acres and fueled by 25 miles per hour winds, the blaze was expected to grow, Los Angeles authorities told the newspaper.

No injuries had been reported.

A fire east of the 405 freeway near the Getty Center has closed the 405 freeway in both directions north of the 10 freeway, says the LA Times.

Evacuations were also issued for Arroyo Street north of the 210 Freeway and areas of Maclay, Pocoima Wash west of Sayre Street and Eldridge, Los Angeles Fire Department spokeswoman Margaret Stewart stated in an update.

On Tuesday evening, a fire official said he suspects hundreds more homes have been destroyed.

Police were forced to shut down nine miles of the Interstate 405 freeway, one of the busiest in the U.S., early on Wednesday morning. A second center is available to evacuees at the Sunland Senior Center at 8640 Fenwick Street.

About 105 patients were voluntarily evacuated from Mountain View Convalescent Center in Sylmar.

For small animals, shelters were in place at West Valley Animal Shelter, 20655 Plummer St., and the East Valley Animal Shelter, 14409 Vanowen St. And the Los Angeles Unified School District said the student bodies of Hubbard and Harding schools in Sylmar would be redirected to San Fernando High School at 11133 O'Melveny Ave.in San Fernando.

The blaze comes amid a red flag warning - due to low humidity and fierce Santa Ana winds - that is expected to last through much of the week.

One resident who was evacuated told KTLA he was surprised at how quickly the winds shifted.

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