X-Plane is flight simulator software. They use OpenStreetMap data to create parts of their 3D scenery (such as roads) blended in with various other sources. X-Plane is commercial paid-for software, but offering free data packs and a community of users sharing 3D models. The desktop version is available for Windows, Linux and Mac OS X; there is also a mobile app.

The X-Plane development blog contains technical details about X-Plane development, including some interesting commentary on the challenges of working with OSM data: