- An interview called the Schedule for Affective Disorders and Schizophrenia for School Age Children Present and Lifetime version (K-SADS-PL) is used to identify mental health problems among children and younger teens. Both the child and a parent are asked questions about the child s behaviors and symptoms that might indicate such problems. Researchers want to see if the K-SADS-PL can help identify mental health problems in young adults (ages 18 to 25). Two groups of young adults, including healthy volunteers and people with cancer, and their parents will participate in this study.

Objectives:

To see if the K-SADS-PL interview used for children and teens can also be used for young adults.

To see whether information provided by parents will affect the rate of mental health problems found.

Eligibility:

Individuals aged 18-25 years who have cancer and are participating in research studies at the National Institutes of Health.

Healthy volunteers aged 18-25 years.

A parent of a young adult who is participating in this study.

Design:

This study requires one study visit that includes an interview and self-report questionnaires. It will take about 1 to 3 hours. A follow-up phone call or visit will also be required.

Young adult participants will be given the K-SADS-PL interview and four questionnaires that ask about mood, anxiety, distress, parental contact, and development during childhood. The K-SADS-PL interview will be video recorded or audio recorded.

Parents will also be given the K-SADS-PL interview. This interview can be done in person or by phone, and will also be recorded.

a. Description of proband patients and healthy volunteers: these adult participants between the ages of 18-25 will be invited to undergo a psychiatric diagnostic interview using the K-SADS PL. Current or past history of mental health problems or treatment is allowed.

b. Proband patient/healthy volunteer inclusion criteria

Age 18-25 years, males and females

English speaking

Participant has contact (face-to-face, phone or electronic) with at least one of his/her parents at least once per week

Enrolled in an NIH CC study (probands) or in good general health (healthy volunteers)

c. Proband patient/healthy volunteer exclusion criteria

Unable to provide informed consent

Known severe intellectual disability such as a history of mental retardation, pervasive developmental disorder or inability to complete an 8th grade education.

Cancer that involves the brain either as primary site of cancer or as a result of metastatic disease.

d. Description of parent participants: If there is more than one parent who is eligible, the parent who knows the participant best will be chosen. For this study, we define parent as a primary caregiver during the participant s early life who directly observed the child s development and is still alive to be interviewed. This could allow for informants who are adoptive parents or other close relatives who raised the child.

e. Parent participant inclusion criteria

English speaking

Parent of a patient proband or healthy volunteer enrolled in the study

Parent has contact (face-to-face, phone or electronic) with his/her child at least once per week

f. Parent participant exclusion criteria

Unable to provide informed consent

Known severe intellectual disability such as a history of mental retardation, pervasive developmental disorder or inability to complete an 8th grade education.

Refusal to be video or audio recorded

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01778478