The authors, led by Sunil Aggarwal of the University of Washington, walk readers through the massive body of medical evidence for marijuana’s safety and efficacy, including “the 33 completed and published American controlled clinical trials with cannabis.” They note that “nearly all of the 33 published controlled clinical trials with cannabis conducted in the United States have shown significant and measurable benefits in subjects receiving the treatment.”

They also point out that the federal government has conducted only one long-term study of medical marijuana, the IND program that still provides marijuana to four patients. But it’s a study in name only, as “no clinical response data in the patient cohort have ever been systematically collected or disseminated.”

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Translation: If officials don’t know that marijuana is a safe, effective medicine, it’s because they don’t want to know.