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The Internet of Things is still one of the most relevant topics in the field of economics and research powered by the increasing demand of innovative services. Cost reductions in manufacturing of IoT hardware and the development of completely new communication ways has led to the point of bil-lions of devices connected to the internet. But in order to rule this new IoT landscape a standardized solution to conquer these challenges must be developed, the IoT Architecture.
This thesis examines the structure, purpose and requirements of IoT Architecture Models in the global IoT landscape and proposes an overview across the selected ones. For that purpose, a struc-tured literature analysis on this topic is conducted within this thesis, including an analysis on three existing research approaches trying to frame this topic and a tool supported evaluation of IoT Archi-tecture literature with over 200 accessed documents.
Furthermore, a coding of literature with the help of the specialised coding tool ATLAS.ti 8 is conduct-ed on 30 different IoT Architecture Models. In a final step these Architecture Models are categorized and compared to each other showing that the environment of IoT and its Architectures gets even more complex the further the research goes.

In this thesis, a computer simulation model created in the early 1960s by Robert P. Abelson and Alex Bernstein is examined. The simulation described was built to reflect processes involved in formation of a public opinion within a population taking into account direct communication as well as communication mediated through mass media. After describing and thoroughly analyzing the available description of the simulation model this thesis produces the implementation of a running software simulation system implementing this model. The software is developed and described using common computer science procedures and finally examined for its properties during different tests.

Currently more than 850 biological databases exist. The majority of biological knowledge is not in these databases but rather contained as free text in scientific literature. For systems biology tasks it is often necessary to integrate and extract data from heterogeneous databases and free text as well as to analyse the information in the context of experimental data. ONDEX is an integration framework which aims to address these challenges by combining features of database integration, text mining and sequence analysis with methods for graph-based data analysis and visualisation. The main topics of this diploma thesis are the redesign of the ONDEX backend, the development of a data exchange format, the development of a query environment and the allocation of Web services for data integration, data exchange and queries. These Web services allow backend workflow control from both local and remote workstations.