I'm about to switch to a 1x10 setup on my HD. I'm running the XTR Shadow + rear derailleur so I'm going to run without the chain guide to start but if it becomes an issue I'm going with the HD specific one from ibis.

I have been running the XTR Shadow plus on my HD with the Ibis/MRP G2 guide with the lower roller/guide removed. The drivetrain is pretty quiet and I have had no dropped chains. I like this setup because you don't get the perceived drag of the lower roller when climbing for an hour.
The only reason I wound up with this setup was because my chain lube of choice ate through the plastic of the lower roller guide. OOOPS!