When He Lan Jun (Jin Shi Jia) had failed to turn up and meet the Empress to treat her skin problem, his position as an imperial doctor was given to his new and cunning student, Pei Yun Tian (Zhang Zhe Han), along with his house and fortune. While on the streets, he then runs into Su Lian Yi (Yang Rong), a girl he had met 5 years ago as a result of a one-night-stand and she quickly agrees to take him in. Believing that his skills as a doctor will one day help him regain his title back, He Lan Jun starts up his own clinic with Su Lian Yi as his main supporter, and with Pei Yun Tian as his new and only rival. Together, the three would find themselves being involved in a series of events which would either cause He Lan Jun to permanently lose his status to Pei Yun Tian, or make him one step closer to beating his former student who had the desire to rise above him.