The measure missed delivering a GOP promise to Americans "to repeal Obamacare and lower their health care costs," they said.

"Well, they're also four good guys, four friends of mine, and I think that they'll probably get there," Trump told Fox News in response to the senators' opposition. "We'll have to see."

Sen. Dean Heller, R-Nev., said on Friday at a Nevada press conference that he would not support the bill. He earlier said in a Thursday statement that he had "serious concerns about the bill’s impact on the Nevadans who depend on Medicaid."