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"Sir, who are you and what are you doing here?" Cruz said. "Are you a little bit confused?"

The first protester was barely off the stage before another one made it within arm's length of the conservative presidential candidate.

"This is not your stage," Cruz said. "This is not your stage."

The disturbance didn't break Cruz's concentration, and he even turned the protest into an attack of his own, citing the state's motto, "Live free or die."

"Am I right that, in fact, it's not, 'Live coddled by a bunch of nanny-state liberals who want to control every aspect of your life or die'?" Cruz said.

He went on to attack Democratic candidate U.S. Sen. Bernie Sanders.

"Boy, it's almost like the Bernie Sanders guys are scared," he said. "The 'Bernistas' are out in force."

In an interview for WMUR's "CloseUP," Cruz said the big Republican field is only an illusion.

"It does seem more and more that this is a two-man race between Donald (Trump) and me," Cruz said.

He said that he believes that Democratic candidate Hillary Clinton's campaign is secretly rooting for Trump, believing him to be more beatable in November. Even so, Cruz resisted the urge to take a swipe at his Republican rival.

"Listen, whether he's a conservative or not will be a judgment that the voters have to make," Cruz said.

Although Cruz has shied away from going after Trump, the politeness isn't being reciprocated. This week, Trump suggested that Cruz isn't even eligible to be president because he was born in Canada. But Cruz called the attack a non-issue.