Fibrocystic Disease of Breast : Apocrine metaplasia

Comments:
Apocrine metaplasia is a frequent finding in fibrocystic disease. The lining cells have abundant eosinophilic granular cytoplasm, prominent nucleolus and apocrine snouts. Immunostain for GCDFP-15 is strongly positive. Presence of cytologic atypia in apocrine metaplasia is not a risk factor for carcinoma.