Ehlers Danlos Syndrome - Cannabis Symptom Relief

Ehlers-Danlos syndrome is a group of inherited disorders marked by extremely loose joints, hyper-elastic skin that bruises easily, and easily damaged blood vessels. Also known as “Cutis hyper-elastica” are a group of connective tissue disorders, caused by a defect in the synthesis of collagen (usually Type I and III). Surgery may help with some of the problems in certain EDS types.
There are six major types and at least five minor types of Ehlers-Danlos syndrome (EDS).
A variety of gene mutations (changes) cause problems with collagen, the material that provide strength and structure to skin, bone, blood vessels, and internal organs.
The abnormal collagen leads to the symptoms associated with EDS. In some forms of the condition this can include rupture of internal organs or abnormal heart valves..
The syndrome, named after two doctors, Edvard Ehlers of Denmark, and Henri-Alexandre Danlos of France, who identified the condition at the turn of the 20th century.

Treatment
There is no specific cure for Ehlers-Danlos syndrome. Individual problems and symptoms are evaluated and cared for appropriately. Frequently, physical therapy or evaluation by a doctor specializing in rehabilitation medicine are needed.

Expectations (prognosis)
People with EDS generally have a normal life span. Intelligence is normal.
Those with the rare vascular type of EDS are at significantly increased risk for rupture of a major organ or blood vessel. These individuals, therefore, have a high risk of sudden death.

Possible complications of Ehlers-Danlos syndrome include:
• Chronic joint pain
• Early-onset arthritis
• Failure of surgical wounds to close (or stitches tear out)
• Premature rupture of membranes during pregnancy
• Rupture of major vessels, including a ruptured aortic aneurysm (only in vascular EDS)
• Rupture of a hollow organ such as the uterus or bowel (only in vascular EDS)
• Rupture of the eyeball

Cardiac effects: Dysautonomia typically accompanied by Valvular heart disease (such as mitral valve prolapse, which creates an increased risk for infective endocarditis during surgery, as well as possibly progressing to a life-threatening degree of severity of the prognosis of mitral valve prolapse)

Difficulty regulating own body temperature

Insensitivity to local anesthetics.

Migraines and headaches, including postural headaches from spontaneous intracranial hypontension

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