Introduction: Hospital information system is comprehensive software aiming to integrate patient information in order to send and exchange information between departments and other medical centers, based on, Since according to the users' needs, some changes such as modifications, improvements or conformity to changes in the organization are applied and also some requirements and performance characteristics are added in these systems so they should be constantly assessed and ranked. The aim of this research is to rank hospital information systems.

Methods: This descriptive study was conducted in 2013. Research population included hospital information systems of the country. The sample size comprised 16 companies. Data were collected from check lists which included information related to research purposes, and its validity was confirmed by experts. The collected data were analyzed using descriptive statistics and SPSS software.

Results: In the overall rating of hospital information systems, “Rayavran” with 72.7% ranked the highest and “BuAli designers” with 47.1% ranked the lowest. In rating functional requirements, only three softwares were efficient. Most of these systems were efficient regarding technical requirements and the ability to use the capabilities of the vendor of the systems, and most hospital information systems were inefficient in improving the quality of patient care.

Conclusion: In general, hospital information systems in Iran had a moderate performance regarding the studied requirements which requires system managers and designers` consideration and attention.