Lead paper author, Shyam Sundhar Bale, noted that the assay is in part developed on the sensitivity of Rolling Circle Amplification (RCA), and is created to be modular so it can be applied to any other antigen-antibody pair without requiring much modification.

Other topics include hybrid nanorods made from sequences of natural trimeric fibrous proteins using the fibritin trimerization motif, the Leucine zipper as a building block for self assembled protein fibers, biomimetic synthesis of biomorphic nanostructures, synthesis and primary characterization of self assembled peptide-based hydrogels,and the assembly of nanospecies on repetitive DNA sequences generated on gold nanoparticles by rolling circle amplification.

Using a technology called Rolling Circle Amplification (RCA) and a DNA polymerase licensed exclusively to Amersham Pharmacia Biotech, the new TempliPhi method provides a cost-effective alternative to growing bacteria and purifying the template prior to sequencing.

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