Patent class list (only not empty are listed)

Deeper subclasses:

Metabolism of micro-organism enhanced (e.g., growth enhancement or increased production of microbial product)

33

20140342428

Genetic Regulation of Bone and Cells by Electromagnetic Stimulation Fields and Uses thereof - The present invention provides methods to modify the genetic regulation of mammalian tissue, bone, cells or any combination thereof by preferential activation, up-regulation and/or down-regulation. The method comprises steps of tuning the predetermined profiles of one or more time-varying stimulation fields by manipulating the B-Field magnitude, rising slew rate, rise time, falling slew rate, fall time, frequency, wavelength, and duty cycle, and exposing mammalian cells or tissues to one or more tuned time-varying stimulation fields with predetermined profiles. Examples of mammalian cells or tissues are chondrocytes, osteoblasts, osteocytes, osteoclasts, nucleus pulposus, associated tissue, or any combination. The resulted modification on gene regulation of these cells, tissues or bones may promote the retention, repair of and reduction of compromised mammalian cartilage, bone, and associated tissue.

11-20-2014

20140248678

LED COMPONENT - An LED component and the use thereof. The component comprises a light output spectrum with at least one peak intensity between 600-800 nm wavelength range with a full width at half maximum at least 50 nm; second optional optical light output peak at 200-500 nm wavelength range; and third optional output peak at 700-1000 nm wavelength range. It can be used for therapeutic, photosynthesis and photomorphogenetic applications.

09-04-2014

20090093037

METHOD AND APPARATUS FOR ACCELERATING GROWTH OF LACTIC ACID BACTERIA WITH ELECTRIC FIELD - The method and apparatus for accelerating growth of lactic acid bacteria, which apply an electric field to the lactic acid bacteria using an electric field in a frequency band of 1 kHz to 1 MHz, can be applied to all lactic acid bacteria used in home and industries to accelerate the growth of them and can be used to increase the number of the lactic acid bacteria and the production of all metabolites (for example, lactic acid and carbon dioxide) of the lactic acid bacteria. The invention increases the lactic acid bacteria and the production of the metabolites of the lactic acid bacteria, thereby activating the beneficial fermentation action of the processed foods such as fermented milk, lactic acid bacteria-containing beverage, toenjang or salted foods (kimchi or pickle and the like). In addition, the invention lowers pH of the foods to suppress the proliferation of the harmful microbes, and makes the low oxygen/oxygen-free environment using the carbon dioxides produced as metabolism by-products, thereby increasing the flavor of the foods and prolonging the preservation period.

04-09-2009

20090317885

Photoactive Metal Nitrosyls For Blood Pressure Regulation And Cancer Therapy - Disclosed are nitric oxide delivery agents and methods of their use, more specifically to photoactive compounds, which are able to perform targeted delivery of nitric oxide in vitro and in vivo and are useful for medicinal applications including, but not limited, to blood pressure regulation and cancer treatment.

12-24-2009

20090233342

HETEROLOGOUS EXPRESSION OF PROTEORHODOPSIN PHOTOSYSTEM - The invention relates to functional heterologous expression of proteorhodopsin photosystems in cells and the use of such proteorhodopsin photosystems in methods for increasing energy content of a cell, redirecting carbon flow in a cell, increasing a production of a carbon-based compound in a cell and increasing production of a metabolite in a cell.

09-17-2009

20110287507

PROCESS FOR GROWING BIOMASS BY MODULATING SUPPLY OF GAS TO REACTION ZONE - There is provided a process of growing a phototrophic biomass in a reaction zone. The reaction zone includes an operative reaction mixture. The operative reaction mixture includes the phototrophic biomass disposed in an aqueous medium. Gaseous exhaust material is produced with a gaseous exhaust material producing process, wherein the gaseous exhaust material includes carbon dioxide. Reaction zone feed material is supplied to the reaction zone such that any carbon dioxide of the reaction zone feed material is received by the phototrophic biomass so as to provide a carbon dioxide-enriched phototrophic biomass in the aqueous medium. The carbon dioxide-enriched phototrophic biomass disposed in the aqueous medium is exposed to photosynthetically active light radiation so as to effect photosynthesis. A discharge of the gaseous exhaust material from the gaseous exhaust material producing process is modulated based on sensing of at least one reaction zone parameter. The modulating of the discharge of the gaseous exhaust material includes modulating of a supply of the discharged gaseous exhaust material to the reaction zone feed material, wherein the discharged gaseous exhaust material which is supplied to the reaction zone feed material defines a gaseous exhaust material reaction zone supply, wherein the gaseous exhaust material reaction zone supply includes carbon dioxide.

11-24-2011

20150044752

Method of Treatment of Mesenchymal Stem Cells - Extracted human mesenchymal cells (MSCs) are placed into the interior space of a closed vessel and exposed to an electric AC current and/or electromagnetic field. The MSCs are also stirred within the vessel to further stimulate the cells, enhancing the osteodifferentiation process during human transplantation of the cells.

02-12-2015

20110171712

SELF-ASSEMBLING TISSUE MODULES - The invention relates to a new approach to constructing cellular aggregates in vitro and their use in methods for producing 3D-tissue constructs in a modular way.

07-14-2011

20100144004

Cell culture system, cell culture substrate thereof and culture method thereof - A cell culture system for directing growth of cells is provided. The cell culture system includes a substrate, a culture layer and a culture medium. The culture layer is located on the substrate. The culture layer includes at least one carbon nanotube film including a plurality of carbon nanotubes orientated primarily along a same direction. The culture medium covers the culture layer and includes at least one growth factor.

06-10-2010

20100221806

APPARATUS AND METHOD FOR GROWING PLANTS, A BIOMASS, OR MICRORGANISMS IN WATER THROUGH PHOTOSYNTHESIS - Presented is an apparatus for growing plants, a biomass, or a microorganism through photosynthesis. The apparatus includes a hollow tube-like structure of flexible transparent material having a first end, a second end, and a middle section, and defining an interior for receiving, through one of the ends, an aqueous solution, a gas comprising carbon dioxide, and at least one of seeds of the plants, a sample of the biomass, and a sample of the microorganism to be grown. The apparatus further includes a support connected to the first or second end of the tube-like structure for positioning the first or second end at a height above the middle section, and an agitator connected to the tube-like structure to impart motion to the aqueous solution in the interior such that when the tube-like structure is exposed to electromagnetic radiation, growth of the plants, biomass, or microorganism occurs through photosynthesis.

09-02-2010

20110189748

ULTRASOUND ENHANCED GROWTH OF MICROORGANISMS. - A method of increasing the rate of growth, useful product production, or protein expression of a microorganism includes the step of exposing the microorganism to ultrasound having a frequency greater than about 1 MHz.

08-04-2011

20100178680

ROTATABLE PERFUSED TIME VARYING ELECTROMAGNETIC FORCE BIOREACTOR AND METHOD OF USING THE SAME - A rotatable perfused time varying electromagnetic force bioreactor with a rotatable perfusable culture chamber and a time varying electromagnetic force source operatively connected to the rotatable perfusable culture chamber. In use, the rotatable perfused time varying electromagnetic force bioreactor supplies a time varying electromagnetic force to the rotatable perfusable culture chamber of the rotatable perfused time varying electromagnetic force bioreactor to expand cells contained therein.

07-15-2010

20130344560

Method for localized photo-irradiation of biological tissues to stimulate tissue regeneration or repair - This invention relates to a method of delivering light energy to biological tissues for the acceleration of healing of damaged or diseased tissues or regeneration of such tissues. More particularly, the present invention relates to applying various wavelengths of light to articular and non-articular joints, alone, or in conjunction with techniques for restoring or regenerating cartilage, ligament and/or tendons whether in-vitro, in-situ or in-vivo. The present invention also extends to application of photo-irradiation to stimulate enhanced proliferation and site-dependent differentiation of stem cells into mature cells and to stimulate full functioning of mature cells involved in tissue repairs for regeneration of tendons, ligaments, cartilage, bone or muscle, depending on the type of tissue with which the stem cells come into contact.

Plasma Oxidation-Reduction Method, Method for Promoting Plant/Animal Growth Using the Same, and Plasma-Generating Device for Use in Method for Promoting Plant/Animal Growth - Provided is a plasma oxidation-reduction method with which it is possible to control the structure of amino acids and proteins with high and stable reproducibility, by using plasma in order to control the amino acids and proteins that make up a living body, particularly by using plasma in order to oxidize or reduce amino acids and proteins. Also provided are a method for promoting plant/animal growth using the plasma oxidation-reduction method, and a plasma-generating device for use in the method for promoting plant/animal growth. Amino acids or proteins are oxidized or reduced in the plasma oxidation-reduction method by using an active oxygen species or active hydrogen in the plasma. Preferably, the active oxygen species comprises any one of singlet oxygen atoms, excited oxygen molecules, or hydroxyl radicals, and the active hydrogen comprises excited hydrogen atoms.

Systems and Methods for Increasing Growth of Biomass Feedstocks - Methods and systems for developing and bio-refining or processing biomass feedstocks into a spectrum of bio-based products which can be used as a substitute for fossil oil derivatives in various types of product manufacturing processes and/or the production of bio-energy are disclosed. In addition, methods and systems for identifying, measuring and controlling key parameters in relation to specific biomass developing processes and bio-refining processes so as to maximize the efficiency and efficacy of such processes while standardizing the underlying parameters to facilitate and enhance large-scale production of bio-based products and/or bio-energy are disclosed.

06-27-2013

20140315271

METHODS FOR IMPROVING THE BIOACTIVITY CHARACTERISTICS OF A SURFACE AND OBJECTS WITH SURFACES IMPROVED THEREBY - A method for improving bioactivity of a surface of an implantable object comprising titania, titanium, an alloy of titanium, and/or polytetrafluoroethylene (PTFE) and implantable objects prepared thereby provides forming an accelerated neutral beam derived from an accelerated gas-cluster ion-beam (GCIB) in a reduced-pressure chamber, introducing an implantable object into the reduced-pressure chamber, and irradiating at least a first portion of the surface of said implantable object with a GCIB-derived neutral beam.

10-23-2014

20090081752

BIOREACTOR, KIT AND METHOD OF USING SAME - A bioreactor, kit, a method of using the device to promoting growing and/or culture of a cell, and a method for regenerating and/or improving the function of mammalian cells. The bioreactor includes a controlling circuit coupled to magnetic field emitter that emits relatively steep and short-lived magnetic field pulses during these an active ephemeral period. The bioreactor also provides a relatively long-term inactive phase in which no magnetic field pulses are imposed. The kit includes the unassembled components of the bioreactor. The method of using the bioreactor and of regenerating and/or improving the function of mammalian cells includes the step of applying a time variant magnetic field through the cell to promote growing and/or culturing, and then introducing the cells to a mammal to regenerate cells.

03-26-2009

20140038258

BIOREACTOR WITH MECHANICAL AND ELECTRICAL STIMULATION MEANS - Disclosed herein is a bioreactor for creating and/or conditioning biological tissues, in particular cardiovascular patches. This bioreactor supports additionally cellular differentiation under controlled conditions. The bioreactor comprises a housing having a first section (

Apparatus and method for growing algae by ionizing radiation - An apparatus is disclosed for growing algae by ionizing radiation. The apparatus includes a container for containing medium for the growth of algae, a filter disposed in the container, a 3-dimensional rack disposed in the container, an adherent element wound on the 3-dimension rack so that spores of the algae can be planted in the adherent element, a radiation element disposed in the container for irradiating the spores and a timepiece connected to the radiation element.

08-26-2010

20090170178

Cell stimulating device and cell stimulating method - It is an object of the present invention to provide an electrical stimulating device for efficiently providing direct electrical stimulation to a large number of nerve cells in vitro without causing any injuries to such cells. The present invention provides a cell stimulating device which comprises: a first electrode serving as a positive or negative electrode that extends from one side of a culture vessel that is used for accommodating cultured cells to a point at which the first electrode is not in contact with the cultured cells or is in contact with the surfaces of the cultured cells; and a second electrode serving as a negative or positive electrode that extends from the other side of the culture vessel to a point at which the second electrode is not in contact with the cultured cells or is in contact with the surfaces of the cultured cells, wherein an electric field for stimulating cells is formed via the first electrode and the second electrode.

RADIOFREQUENCY DEVICE FOR INCREASING INTRACELLULAR BIOACTIVE SUBSTANCE AND PLANT CELL CULTURE METHOD USING THE SAME - There are provided a radiofrequency device for increasing amount of a bioactive substance in a plant cell and a plant cell culture method for increasing amount of useful intracellular secondary metabolites by using the radiofrequency device. The cell culture method of the present invention makes it possible to increase specific secondary metabolites such as daidzein, equol, and the like in a cell and thus can be used for development into various medicines, agricultural pesticides, spices, pigments, food additives, and cosmetics containing bioactive substances. Further, the cell culture method of the present invention improves conventional cell culture methods limitedly used for specific cells or specific metabolites for increasing amount of intracellular bioactive substances and thus can be widely applied to production of cells and secondary metabolites.

Method and device for producing biomass of photosynthesizing microorganisms/phototrophical algae and biomass of these microorganisms pigments - The invention relates to biotechnology, in particular to methods and means of physical action on biological structures of photosynthesing microorganisms, phototrophic algae in particular. The invention can be used in pharmaceutical, cosmetic and foodstuff industries, as well as for obtaining biofuel from algae In the process of the method implementation radiation of cultivated solution of photosynthesizing microorganisms/phototrophical algae is carried out by the action of electromagnetic waves of mm range and low intensity. Stimulation of increasing photosynthesizing microorganisms/phototrophical algae biomass and biomass of their pigments (excretions) is obtained with industrial production as a result of the resonance effect which is caused by the interaction of electromagnetic wave and biological cell. Irradiation of cultivated solution of photosynthesizing microorganisms/phototrophical algae is performed by electromagnetic waves of mm range and low intensity at different phases of cultured biological objects development.

02-05-2009

20110159562

APPARATUS AND METHODS FOR CONTROLLING CELLULAR DEVELOPMENT - According to one aspect and example, a method for facilitating cellular interactions in biological tissue provides controllable activation of a selected type of stem cell among a plurality of cell types present in the tissue. The method includes various steps including the introduction of a microbial opsin into a region of the tissue that includes a selected type of stem cell, by expressing the microbial opsin in the stem cell. A light source is then introduced near the stem cell, and the light source is used to controllably activate the light source to direct pulses of illumination from the light source to the selected type of stem cell, for selectively controlling the growth and development of the stem cell in a manner that is independent of the growth and development of the other types of cells.

06-30-2011

20140199745

ELECTROKINETIC CONFINEMENT OF NEURITE GROWTH FOR DYNAMICALLY CONFIGURABLE NEURAL NETWORKS - Systems and methods for altering neurite growth are generally described. In some embodiments, a system may include a neuron comprising a neurite and electrodes able to generate a physical guidance cue. The physical guidance cue may be used to alter the growth of the neurite and may be temporally and spatially dynamic, such that neurite growth may be altered in a spatial and/or temporal manner. Dynamic control of neurite growth may be used to form directional neural connections, intersections, and/or overlaps.

07-17-2014

20140199746

ELECTROKINETIC CONFINEMENT OF NEURITE GROWTH FOR DYNAMICALLY CONFIGURABLE NEURAL NETWORKS - Systems and methods for altering neurite growth are generally described. In some embodiments, a system may include a neuron comprising a neurite and electrodes able to generate a physical guidance cue. The physical guidance cue may be used to alter the growth of the neurite and may be temporally and spatially dynamic, such that neurite growth may be altered in a spatial and/or temporal manner. Dynamic control of neurite growth may be used to form directional neural connections, intersections, and/or overlaps.

07-17-2014

20130267003

Methods for Culturing Cells in an Alternating Ionic Magnetic Resonance (AIMR) Multiple-Chambered Culture Apparatus - Provided herein are methods for culturing cells, tissues or organoid bodies in the presence of a pulsating alternating ionic magnetic resonance field and models comprising a tissue-like assembly of the cells so cultured. The cells, tissues or organoid bodies are introduced into a culture unit comprising growth and nutrient modules in which the gravity vector of the growth unit is continually randomized and cultured in the presence of the alternating ionic magnetic resonance field.

10-10-2013

20140113345

Apparatus and Method for Culturing Cells and Tissue - An apparatus that provides synchronized chronic electrical stimulation and chronic stretch to a cell culture or tissue. The apparatus includes a programmable controller which synchronizes stretch and electrical stimulation applied to a deformable culture container, such as a silicone rubber culture dish. The apparatus is used to treat cells and retard de-differentiation or promote differentiation and maturation in some applications.