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Research Summary

My current research interest is to develop imaging biomarkers in the field of Clinical Neurosciences by using advanced MRI techniques. The aims are (1) to understand the pathophysiology of diseases… read more

Current Research

My current research interest is to develop imaging biomarkers in the field of Clinical Neurosciences by using advanced MRI techniques. The aims are (1) to understand the pathophysiology of diseases or complex symptoms across diseases, (2) to improve diagnostic accuracy, and (3) to predict and assess therapeutic interventions. Methods used are MR proton spectroscopy, diffusion tensor imaging, perfusion, relaxometry, high resolution carotid imaging and combined electrophysiological/functional MRI with special interst in brian connectivity analysis. The clinical applications are for prediction of risk of stroke, monitoring neurodegeneration, classification and response prediction in paediatric and adult brain cancer, and understanding the neural basis of pain and depression treatment.

Past Research

My past research between 1994 and 2004 focused on using MRI to characterise mental disorders, especially major depression and schizophrenia and CADASIL.