On stage at the Startup Grind conference in Redwood City, California, on Wednesday, venture capitalist Marc Andreessen declined to talk about Zenefits specifically, but he continued to advocate the move-fast mentality.

"This is not a business for the shy," Andreessen, a cofounder of Andreessen Horowitz, said. "This is not a business for passive. This is a business for the aggressive."

Zenefits was its own situation, but the move-fast mantra has worked and will work for other companies, he insisted.

Facebook, another investment, is the obvious example of a company that used the phrase as its motto— and it turned into a $300 billion business that reaches a billion users every day. Being aggressive is something companies, not just startups, need to be doing so they don't get disrupted themselves, he said.

"There is a real art form to it, and a real science," Andreessen said.