2. Manuscripts are accepted for publication in the Journal on the understanding that the content has not been published or submitted for publication elsewhere. This must be stated in the covering letter.

3. Except where otherwise stated, manuscripts are peer reviewed by two or three anonymous reviewers. The editorial board reserves the right to refuse any material for publication and advises that authors should retain copies of submitted manuscripts and correspondence as material cannot be returned.

4. Manuscripts must be type–written on one side of ISO A4 paper ( 212 * 297 mm ) using double-spacing throughout with 2.5 cm margins on all side of the paper.

5. Each manuscript section should begin on a new page, in the following sequence: (a) A Submittal letter with signed consent for publication and declaration that the material has not been published or submitted elsewhere for publication, signed by all authors (b) Title page (c) Abstract and Keywords (d) Text (e) Acknowledgements (if any) (f) References (g) Tables (each table complete with title and footnotes on a separate page) (h) Figures & illustration .

6. The title page should carry a) The title of the article, which should be concise, but informative; b) full name, highest academic degree, institutional affiliation, and full addresses (including fax number and e-mail address) of each author; c) the name of the department(s) and institution(s) to which the work should be attributed; d) the name and address of the author responsible for correspondence about the manuscript; e) source(s) of support in the form of grants, equipment, drugs, or all of these; and f) a short running head or footline of no more than 40 characters (count letters and spaces) at the foot of the title page.

7. Abstract and Keywords: Each manuscript should carry an structured abstract that specifically summarizes the content of the paper in no more than 300 words. The abstract should include four paragraphs, each one designated to the following: Purpose , Methods , Results , and Conclusion . Emphasize new and important aspects of the study or observations. The purpose of the abstract is to allow the content of the paper to be understood independently. Do not use abbreviations in the abstract. Following the abstract authors should provide, and identify as such, 3 to 5 keywords or short phrases that will assist indexers in cross-indexing the article and may be published with the abstract. Terms from the Medical Subject Headings (MeSH) list of Index Medicus should be used; if suitable MeSH terms are not yet available for recently introduced terms, present terms may be used.

8. Text: All manuscripts must follow generally recognized standards for presenting scientific material. The Introduction should state the subject of the study and the problem; should refer only to the most pertinent past publications and should not be an extensive review of the literature . Methods should accurately and clearly describe methods and materials used and/or the patient population studied and should be written with sufficient detail to permit others to duplicate the work. Results must be concise. Discussion should elucidate the results, relate them to the work of others, and describe their significance, and should be restricted to the significant findings presented. Digressions and theorizing are not appropriate.

9. References: References should follow text and begin on a separate page. They must be double-spaced and numbered consecutively in order of appearance in the text. In text, designate references by superscript numbers following all punctuation (except semicolons). Use the style of the examples below, which are based on the formats used by the National Library of Medicine (NLM) in Index Medicus. The titles of journals should be abbreviated according to the style used in Index Medicus.

10. Acknowledgments: List all contributors who do not meet the criteria for authorship, such as a person who provided purely technical help, writing assistance, or a department chair who provided only general support. Financial and material support should also be acknowledged.

11. Tables: Type or print out each table with double spacing on a separate sheet of paper. Number tables consecutively in the order of their first citation in the text and supply a brief title for each. Give each column a short or abbreviated heading. Place explanatory matter in footnotes, not in the heading. Explain in footnotes all nonstandard abbreviations that are used in each table. For footnotes use the following symbols, in this sequence: * , †, ‡, §, ||, ¶, **, ††, ‡‡

Table numbers should appear at the top of each table in the order in which they are referenced in the manuscript, along with a short descriptive title. Abbreviations used in tables that are not commonly understood terms should be explained in a legend. Material that is in the tables should not be repeated in the text.

12. Figures and Illustrations:All figures should be numbered in the order in which they are referred to in the text. The legends for figures should be a brief description that allows the figure to be fully understood. Material that is in the legends for figures should not be repeated in the text. Submit three identical sets of illustrations, with each set in a separate envelope. On the back of each illustration, place a label containing the figure number, an indication of orientation (eg, top, left), and the running title of the manuscript.

Only unmounted glossy prints or high-quality, camera-ready laser generated illustrations are acceptable. Illustrations in electronic format are acceptable, provided that these instructions are followed: Submit color or black-and-white images on disk with hard copy proof. Submit images in JPEG or BMP format include the following information: platform, software program, medium, format, fonts, naming convention, and color separation. Photographs that are 8*12 cm are preferred. High-quality photocopies of illustrations should be appended to the body of the manuscript after the tables. Color illustrations or photographs are acceptable

13. A major review article that thoroughly cover a subject would be published in each issue of the journal.

14. Upon acceptance of the article for publication, a digital file (in Microsoft word format) should be submit for editorial processing.

15. Authors must take full responsibility for their contributions and have approved the final manuscript.