Glucosamine - Drugs and Supplements - Mayo Clinic

Consult a healthcare provider immediay if you experience side effects. Avoid in people with a known allergy or sensitivity to glucosamine sulfate or its parts.

Use cautiously when taking recommended doses over a long time period or if injected into the muscle. Use cautiously if using doses higher than those recommended. Use cautiously in people with low blood plaet counts, as glucosamine may interact with antibodies.

The U.S. Food and Drug Administration does not strictly regulate herbs and supplements. There is no guarantee of strength, purity or safety of products, and effects may vary. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy.

What are the Possible Side Effects of Glucosamine?

Side effects of glucosamine may include drowsiness, headache, insomnia, and mild and temporary digestive complaints such as abdominal.

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Since glucosamine supplements may be made from shellfish, people with allergies to shellfish should avoid glucosamine unless it has been confirmed that it is from a non-shellfish source. The source of glucosamine is not required to be printed on the label, so it may require a phone call to the manufacturer.

Glucosamine Sulfate Effectiveness, Safety, and Drug Interactions on

Glucosamine sulfate seems to be safe for most people. It can cause some mild side effects including nausea, heartburn, diarrhea, and constipation. Uncommon.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088. Share this Article:

Some preliminary research suggests that glucosamine sulfate might raise blood sugar in people with diabetes. However, more reliable research indicates that glucosamine sulfate does not seem to significantly affect blood sugar control in people with type 2 diabetes. Glucosamine with routine blood sugar monitoring appears to be safe for most people with diabetes.

Glucosamine sulfate seems to be safe for most people. It can cause some mild side effects including nausea, heartburn, diarrhea, and constipation. Uncommon side effects are drowsiness, skin reactions, and headache. Some glucosamine products do not contain the labeled amount of glucosamine or contain excessive amounts of manganese. Ask your healthcare professional about reliable brands.

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Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Next: How does Glucosamine Sulfate work?

There is some concern that glucosamine products might cause allergic reactions in people who are sensitive to shellfish. Glucosamine is produced from the shells of shrimp, lobster, and crabs. But allergic reactions in people with shellfish allergy are caused by the meat of shellfish, not the shell. There are no reports of allergic reactions to glucosamine in people who are allergic to shellfish. There is also some information that people with shellfish allergy can safely take glucosamine products... Read More: