This lesson helps students explore the functions of the kidney and its ...
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This lesson helps students explore the functions of the kidney and its place in the urinary system. Students learn how engineers design instruments to help people when kidneys are not functioning properly or when environmental conditions change, such as kidney function in space.
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This is a hands-on creative group project in which the students will ...
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This is a hands-on creative group project in which the students will create and build a nephron structure, and using a detailed worksheet and labeled solutes, follow the initial filtrate at the glomerulus through filtration, reabsorption and secretion in the production of urine. Creatinine, distal convoluted tubule, glomerular filtrate, Penicillin, pesticides, proximal convoluted tubule, toxins, tubular lumen
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Dietary K intake plays an important role in the regulation of K ...
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Dietary K intake plays an important role in the regulation of K secretion: a decrease stimulates and an increase suppresses kidney expression of protein tyrosine kinase (PTK), which plays a role in regulating Kir1.1 (ROMK), which is responsible for K secretion in the cortical collecting duct (CCD) and K recycling in the thick ascending limb. Tyrosine phosphorylation of ROMK channels increases with low dietary K and decreases with high dietary K. Moreover, stimulation of tyrosine phosphorylation of ROMK1 enhances ROMK1 internalization and reduces the K channel number in the cell surface in the CCD.
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This is a hands on group activity in which the students will ...
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This is a hands on group activity in which the students will work along with the instructor by adding and removing substances along the nephron to gain a greater understanding of filtration, reabsorption, secretion, and excretion. afferent arteriole, creatinine, glomerular capsule, glomerular space, magnesium, proximal convoluted tubule, renal papillae
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