USES: Rizatriptan is used to treat migraines. It helps to relieve
headaches, pain and other symptoms of migraines, including sensitivity to
light/sound, nausea, and vomiting.

Prompt treatment allows you to get back to your normal routine and may
decrease your need for other pain medications. Rizatriptan does not prevent
future migraines or reduce how often you may get a headache.

HOW TO USE: Take this medication by mouth at the first sign of a
migraine, or as directed by your doctor. It may be taken with or without
food, although faster relief may occur when it is taken on an empty stomach.
Do not take rizatriptan to prevent a migraine. If there is no improvement in
your symptoms, do not take any more doses of this medication before talking
to your doctor.

If you have never taken this medication before and you have risk factors for
heart diseaseyou may be advised to take your first dose in your doctor's
office in order to monitor for rare but serious heart problemsYour dosage is
based on your medical condition and response to therapy.

SIDE EFFECTS: Drowsiness, dizziness, dry mouth,
numbness/tingling/prickling sensations, redness (flushing),
tiredness/weakness may occur. If these effects persist or worsen, notify
your doctorChest/jaw/neck tightness can commonly occur shortly after using
rizatriptan. Only rarely are these signs of a serious condition. However,
you may not be able to tell this apart from a serious reaction related to a
lack of blood flow to the heart, brain or other parts of the body.

Seek immediate medical attention if any of these unlikely but very serious
(rarely fatal) side effects occur: chest pain, jaw/left arm pain, fainting,
fast/irregular/pounding heartbeat, vision changes, weakness on one side of
the body, confusion, slurred speech, sudden or severe stomach/abdominal
pain, bloody diarrhea. This medication may rarely cause a very serious
condition called serotonin syndrome.

The risk increases when this medication is taken with certain other drugs
such as otherused to treat migraine headachescertain antidepressants
including SSRIsand NSRIsBefore taking this drug, tell your doctor if you
take any of these medications.

Serotonin syndrome may be more likely when you start or increase the dose of
any of these medicationsn the unlikely event you have a serious allergic
reaction to this drug, seek immediate medical attention. Symptoms of a
serious allergic reaction include: rash, itching, swelling, severe
dizziness, trouble breathing.

PRECAUTIONS: Before taking rizatriptan, tell your doctor or
pharmacist if you are allergic to it; or to other triptan migraine drugs; or
if you have any other allergies. This medication should not be taken if you
have certain medical conditions.