Top "Tonight Show" Moments

During her interview, Fallon asked the “The Hundred-Foot Journey” actress about meeting Queen Elizabeth II. Mirren explained that when people meet the queen, their voice changes.

“You get this thing called Queen-itis which is like a terrible virus that hits you the minute you are in front of the queen,” Mirren explained. “You start saying weird things like ‘it was terribly good fun’, and ‘frightfully nice to meet you’. This weird voice comes out.”