Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, ICC and most other immunological methods.

Specificity

Tested positive against native antigen.

Purity

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

Storage

Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

Background

Antigen Description

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved for left-right pattern formation during embryogenesis.