modulates interplay between the actin cytoskeleton and plasma membrane to promote the maintenance of intercellular contacts in kidney epithelia

required for neural fold elevation and apical constriction along with cell polarization and elongation in both the superficial and deep layers of the anterior neural plate

enhances the localization of the epidermal growth factor receptor (EGFR) to the plasma membrane

MTSS1 positively modulates EGF signaling at low cell densities to promote proliferation and, therefore, may be beneficial for the early stages of primary head and neck squamous carcinoma cells tumor growth