The sound of new-born lambs bleating is something that most people would be happy to wake up to on a Spring morning – or perhaps not? Noise consultant Louise Alderson, had the unusual assignment of monitoring noise levels from baby lambs and their mothers on a farm in Cumbria following a planning application to build a housing development on nearby fields – owned by the same ...

Abstract Silence-GIS is a larse scale noise management system build as an extension on ArcGIS 9.3.1. This system has been designed and developed for the Dutch Highway Authorities. The aim of the system is to support decisions on Dutch and European noise policy and to predict the effect of future measures on the noise exposure of the population in The Netherlands. The information needed to ...

The effect of voids on the acoustic performance of a perforated dissipative expansion chamber is investigated by axially staggering filled/empty segments external to the perforations. A two-dimensional analytical approach is used to determine the Transmission Loss (TL) through pressure and velocity matching at the boundaries of the inlet/outlet ducts, rigid end-plates, and the interfaces between ...

Increasing demands for higher productivity, lower noise and reduced emissions call for totally new approaches when it comes to designing Refuse Trucks. Manufacturers and fleet operators are already under extreme pressure to reduce fuel consumption and CO2 emission. Partly driven by new legislation including CO2 penalty, partly driven by increasing fuel prices and partly driven by the constantly ...

DNA methylation and chromatin modification operate along a common pathway to repress transcription; accordingly, several experiments demonstrate that the effects of DNA methylation can spread in cis and do not require promoter modification. In order to investigate the molecular details of the inhibitory effect of methylation, we microinjected into Xenopus oocytes a series of constructs containing ...

If you play white noise to a group of people and tell them that the song “White Christmas” is hidden in the sound, about 30% of them will be convinced that they can hear it. The human mind is always looking for patterns – even when they aren’t there. This propensity explains a significant proportion of complaints where noise levels are actually very low (they can be close ...

The propagation of epigenetic marks has received a great deal of attention, yet the initiation of epigenetic silencing of a new transgene, virus, or transposable element (TE) remains enigmatic. The overlapping and simultaneous function of multiple silencing mechanisms has obscured this area of investigation. Here, we have revealed two broad mechanisms that can initiate silencing independently: ...

With reactive silencers, AERZEN reduces the noise emissions on the discharge side of its screw compressors, positive displacement blowers, and rotary lobe compressors. The innovative concept of these reactive silencers is superior to classic dissipative silencers in many respects. The sound waves developing on the discharge side of a Delta Screw compressor made by AERZEN can reach 170 to 190 dB. ...

The genus Aspergillus is ideally suited for the investigation of RNA silencing evolution because it includes species that have experienced a variety of RNA silencing gene changes. Our work on this subject begins here with the model species Aspergillus nidulans. Filamentous ascomycete fungi generally each encode two of the core RNA silencing ...

Abstract Silence is the main noise management system for the Dutch highways and is used by the Dutch Ministry of Transport. The Silence system comprises IT infrastructure, environmental data, noise management software, an organisation, procedures and maintenance. Typical noise management system tasks involve data management, setup noise management software, software customisation, ...

The heterogeneous nuclear ribonucleoprotein H (hnRNP) family of proteins has been shown to activate exon inclusion by binding intronic G triplets. Much less is known, however, about how hnRNP H and hnRNP F silence exons. In this study, we identify hnRNP H and hnRNP F proteins as being novel silencers of fibroblast growth factor receptor 2 exon ...

Saccharomyces cerevisiae chromosome III encodes 11 autonomously replicating sequence (ARS) elements that function as chromosomal replicators. The essential 11-bp ARS consensus sequence (ACS) that binds the origin recognition complex (ORC) has been experimentally defined for most of these replicators but not for ARS318 (HMR-I), which is one of ...

Generating power with natural gas engines in large commercial buildings, while controlling emissions and noise from the engines requires a unique catalytic solution. Johnson Matthey’s new QXC model 3-Way converter silencer was chosen for the task. This design contains a unique catalyst element sealing system ...

Problem: an extract system fan drone creating a potential environmental noise problem. Solution: aerodynamic engineering instead of silencers – in keeping with the Red Bull Technology ethos. The conventional technique used to reduce fan tones like this is a silencer – a large, palliative silencer that doesn’t tackle the source of the ...

The acoustic performance of a dissipative expansion chamber lined with two concentric, annular layers of fibrous material with different resistances is investigated. A two-dimensional analytical approach is used to determine the transmission loss of this dissipative silencer. From the boundary conditions at the rigid wall, and the interfaces between the fibre layers and the central airway, the ...

Using database searches of the completed Paramecium tetraurelia macronuclear genome with the metazoan SNAP-25 homologues, we identified a single 21-kDa Qb/c-SNARE in this ciliated protozoan, named P. tetraurelia SNAP (PtSNAP), containing the characteristic dual heptad repeat SNARE motifs of SNAP-25. The presence of only a single Qb/c class SNARE ...

The goal of the present investigation is to reveal the role of the Poly(propyleneimine) (PPI) dendrimer structure on the siRNA nanoparticles formation, facilitation of cell internalisation, and sequence specific knockdown of targeted genes. It was found that the higher generations of PPI dendrimers (G4 and G5) most effectively initiated the complexation of siRNA into discrete nanoparticles when ...

Silencing of gene expression by siRNA holds a promise both for a drug target discovery and as a therapy. Major bottlenecks of siRNA technology include 'off-target' silencing effects and problems with siRNA degradation before delivery. We propose a two-fold approach aimed at curtailing described shortcomings. First, before pre-clinical tests each siRNA shall be matched to comprehensive redundancy ...

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