Publications38

Jim ChilcottSchool of Health and Related Research Rapid Reviews Group, School of Health and Related Research, University of SheffieldBMJ 326:522; discussion 522. 2003

..To evaluate the cost effectiveness of four disease modifying treatments (interferon betas and glatiramer acetate) for relapsing remitting and secondary progressive multiple sclerosis in the United Kingdom...

..As an illustration of such an approach, we estimated annual health service resource requirements and health outcomes over the first decade of a population-based colorectal cancer screening programme in Ireland...

Using whole disease modeling to inform resource allocation decisions: economic evaluation of a clinical guideline for colorectal cancer using a single model

Paul TappendenHealth Economics and Decision Science, School of Health and Related Research, University of Sheffield, Sheffield, UKValue Health 16:542-53. 2013

..To assess the feasibility and value of simulating whole disease and treatment pathways within a single model to provide a common economic basis for informing resource allocation decisions...

P TappendenHealth Economics and Decision Science HEDS, School of Health and Related Research ScHARR, University of Sheffield, Sheffield, UKBone Marrow Transplant 45:1014-21. 2010

..We conclude that HSCT could potentially achieve an acceptable level of cost-effectiveness. However, caution should be exercised as large, high-quality RCTs comparing HSCT versus mitoxantrone are necessary to validate these findings...

The clinical and cost-effectiveness of oxaliplatin and capecitabine for the adjuvant treatment of colon cancer: systematic review and economic evaluation

A PandorSchool of Health and Related Research ScHARR, University of Sheffield, UKHealth Technol Assess 10:iii-iv, xi-xiv, 1-185. 2006

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Antioxidants in the chemoprevention of colorectal cancer and colorectal adenomas in the general population: a systematic review and meta-analysis

D PapaioannouHealth Economics and Decision Science HEDS, School of Health and Related Research ScHARR, University of Sheffield, Sheffield, UKColorectal Dis 13:1085-99. 2011

..This review aimed to assess the present evidence on the effect of antioxidants on the incidence of colorectal neoplasms in the general population...

The use of irinotecan, oxaliplatin and raltitrexed for the treatment of advanced colorectal cancer: systematic review and economic evaluation

..Future research should attempt to elucidate uncertainties concerning the optimal roles of capecitabine and/or oxaliplatin in the adjuvant setting in order to achieve the maximum level of clinical benefit...

A review and critique of modelling in prioritising and designing screening programmes

..Numerous error avoidance/identification strategies could be adopted but it is difficult to evaluate the merits of strategies for improving the credibility of models without first developing an understanding of error types and causes...

..There is a need for large-scale, long-term studies comparing the effectiveness of combination therapy that includes pioglitazone with that of other combinations of antidiabetic drugs...

Supplemental calcium in the chemoprevention of colorectal cancer: a systematic review and meta-analysis

Christopher CarrollHealth Economics and Decision Science, School of Health and Related Research, University of Sheffield, Sheffield, United KingdomClin Ther 32:789-803. 2010

..The aim of the review was to assess the evidence for the effectiveness of calcium in reducing the recurrence of adenomas and the occurrence of colorectal cancer among populations at high, intermediate, and low risk of the disease...

The economics of routine antenatal anti-D prophylaxis for pregnant women who are rhesus negative

Jim ChilcottSchool of Health and Related Research ScHARR, University of Sheffield, UKBJOG 111:903-7. 2004

..To investigate the economics of routine antenatal anti-D prophylaxis in the prevention of haemolytic disease of the newborn, in support of the NICE appraisals process...