Third International Symposium on Monoliths (Portoroz, Slovenia, May 30-June 4, 2008) expanded upon research trends, potential applications and future of monolith technology. Monoliths, which are considered to be the fourth generation of chromatography materials, have become one of the most important stationary media for chromatographic separations of therapeutic proteins, plasmids and viruses both in analytical and preparative levels. Protista Biotechnology had presented at the Symposium research and development of macroporous monolithic columns (cryogel monoliths) suited for processing the particulate containing fluids as crude cell homogenates, virus- and cell- suspensions, whole blood, etc.