Updated statistics with estimated new cases and deaths for 2015 (cited American Cancer Society as reference 1).

Added text about the Million Women Study, a cohort study conducted in the United Kingdom in more than one million women aged 50 to 64 years, which observed a statistically significant decreased risk of endometrial cancer associated with continuous combined estrogen-progestin therapy, compared with never-users; a similar finding was observed in the European Prospective Investigation into Cancer and Nutrition cohort, with a decreased risk associated with continuous estrogen-progestin therapy, but this association was based on only three exposed cases. Also added that these observed risks were similar to those observed in the NIH-AARP Diet and Health Study Cohort (cited Beral et al., Allen et al., and Trabert et al. as references 49, 50, and 51, respectively).