The following day, Ali and the Bedouin are led by Salim and Nate in an ambush on Katherine Marlowe's caravan, which is heading through the Rub' al Khali with Nate's friend and mentor Victor "Sully" Sullivan. Ali and the Bedouin are able to defeat the caravan and Nate is reunited with Sully. Ali and the Bedouin, along with Nate and Sully, must then continue on to Iram of the Pillars in an attempt to stop Marlowe from entering Iram. However, when a sandstorm then engulfs the Rub' al Khali, Ali, Salim and the Bedouin are separated from Nate and Sully; Nate and Sully must then make their way into Iram alone.[1]

Ali first appears in the 2011 video game Uncharted 3: Drake's Deception. Although he has a minor role in the game's Campaign, he has a more significant role in the multiplayer component of the game; he is available for use as a Hero skin when purchased from the PlayStation Store, either individually or as part of Rogues Skin Pack 1.[2] In Uncharted 3: Drake's Deception multiplayer, Ali's customisation options are: Bedouin Jacket (torso) and Desert Pants (legs).