Research in the Delaney laboratory aims to understand the biological consequences of DNA damage. Using the methods and tools of biochemistry, biophysics, and molecular biology we probe the effects of DNA damage from the molecular to the cellular level. We exploit our abilities to synthesize modified DNA nucleobases and study their properties within well-defined systems. We are particularly interested in the role of packaging of DNA into chromatin and how that packaging influences repair of DNA damage.

News

March 2018: Our research is featured on the cover of Biochemistry. [link]

February 2018: Adam Garlow joins the lab as a chemistry graduate student. Welcome to the lab!

January 2018: Katie and Mary publish their research in Biochemistry. [link]

January 2018: Undergraduates Doug Shea '19 and Will Patterson '20 join the lab.

September 2017: Katie successfully defended her PhD thesis. Congratulations Dr. Bilotti! We wish Katie well as she begins a postdoctoral position at New England Biolabs.