This study was conducted to determine the electrophoretic pattern of serum protein in goats infected withBabesia ovis. Serum total protein was calculated and serum electrophoresis from 15 goats naturally infectedwith B. ovis as well as same number of healthy goats was performed. Microscopic examination of Giemsastained peripheral blood smears revealed B. ovis infection. The parasitological diagnosis was confirmed using polymerase chain reaction (PCR) assay by using a pair of B. ovis-specific primers. Mean values total protein and α and γ globulin fractions in infected goats were significantly higher (P<0.05) than those observed in the healthy group.