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Professor Alain Bousquet-Mélou and colleagues propose a new 5-day workshop on PK/PD modelling. The workshop will be held in Toulouse from Monday 27 June to Friday 1st July 2016. There is a maximum of 25 places available. Please find the provisional program here.

This 5-day workshop is designed for ECVPT residents, PhD students and professionals in academia, industry, or regulatory authorities, working in veterinary pharmacology who wish to improve their pharmacokinetic, toxicokinetic and pharmacodynamic modelling skills. The workshop includes a combination of lectures aiming at presenting key technical and theoretical modelling issues. The content presented and discussed in the lectures will then be illustrated by a series of computer-based hands-on case studies.

The hands-on exercises will be performed in round-table setting. All participants are required to bring their own laptop computer. The participants will be guided through the exercises by instructors with the help of an overhead projector. Active participation in discussions in class is essential.

If you are interested in attending please fill up the registration form available here. This is not a guarantee of a place at the workshop. Registration confirmation will be sent out and payment in full must be received 3 weeks before starting date.

DAY1 - Monday

08:30-9:00

Meet & Greet – An overview of the course

ALAIN BOUSQUET-MELOU

09:00-10:30

Lecture 1

Linearity vs. Non-linearity & Linear vs. non-linear regression: The goal is to introduce the main basic statistical concepts that will be used during the course.

Use of Phoenix for more complex model analysis: The case of a One-compartmental model with Simultaneous IV, oral and IM dosing for a new antibiotic in pigs

PIERRE-LOUIS TOUTAIN and others

16:00-16:30

Afternoon break, coffee

16:30-18:00

Exercise 9

Deconvolution analysis vs. modeling to document process of a drug absorption. How to simulate a single compartmental model with two rate constants of absorption (model build with differential equations) , introduction of a noise in the data set and how to usedeconvolutionto re-estimate the rate constant from the simulated data set

PIERRE-LOUIS TOUTAIN

19:30

Workshop diner

DAY5 - Friday

09:00-10:00

Lecture 12

Plasma protein binding: an overview

ALAIN BOUSQUET-MELOU

10:00-10:30

Morning break, coffee

10:30-12:00

Exercise 10

Estimation of Bmax, Kd and NS using linear and non-linear regression.

PIERRE-LOUIS TOUTAIN

12:00-13:30

Lunch

13:30-16:00

Exercise 11

How to build a rather advanced model using the Graphical model editor of Phoenix