The Truxtun (DDG 103) honors Commodore Thomas Truxtun (1755-1822) who was selected as one of the Navy’s first six captains on June 4, 1798. He was assigned command of USS Constellation, one of the new frigates, and he put to sea to prosecute the undeclared naval war with revolutionary France. On Feb. 9, 1799, Truxtun scored the first of his two most famous victories. After an hour's fight, Constellation battered the French warship L’Insurgente into submission in one of the most illustrious battles of the Quasi-War with France.

May 20, 2006 The guided-missile destroyer suffered a major electrical fire during construction at NGSS Ingalls, Pascagoula, Miss.

June 2, 2007 The Pre-Commissioning Unit (PCU) Truxtun was christened during a ceremony at NGSS Ingalls shipyard in Pascagoula, Mississippi. Cmdr. Timothy R. Weber is the prospective commanding officer.

October 24, 2008 The Truxtun was delivered to the U.S. Navy and is scheduled to be commissioned in the spring of 2009.

March 22, 2009 DDG 103 answered distress call, after the 45-foot sailing vessel Calypso Queen reported a broken mast and sail, as well as electrical and mechanical casualties in the Gulf of Mexico. The crew, a man and a woman, were transferred to Truxtun and required no medical assistance. The vessel was taken under tow and will be turned over to the Coast Guard.

April 25, USS Truxtun was commissioned during an 11 a.m. ceremony at Naval Weapons Station Charleston, South Carolina. Carol Leigh Roelker and Susan Scott Martin, descendants of the ship's namesake, served as sponsors of the ship.

May 1, The Truxtun arrived in its new homeport of Naval Station Norfolk for the first time.

February 17, 2010 Capt. Richard A. Rogers, Commander, Destroyer Squadron 22, relieved of duty CO Cmdr. Timothy R. Weber because of a loss of confidence in his ability to command. He was fired as a result of an ongoing investigation into allegations that he was involved in an inappropriate relationship with a female officer who had been a member of his wardroom. Capt. Jeffrey S. Wolstenholme assumed temporary command of Truxtun.

March 13, DDG 103 moored at Berth 7, Container Terminal in Varna, Bulgaria, for a three-day port call. Participated in PASSEX again on March 19; Departed Black Sea on March 21; Brief stop at Souda Bay on March 23; Transited Suez Canal on March 25.

April 1, The Truxtun is currently underway in the Red Sea for Suez Canal escort operations. Brief stop in Djibouti on April 3; Transited Suez Canal northbound (#2) on April 7; Transited soutbound on April 9; Escorted the USS San Juan (SSN 751) northbound (#4) on April 15.

April 22, Cmdr. Andrew D. Bates relieved Cmdr. Andrew M. Biehn as the 5th CO of Truxtun during a change-of-command ceremony on board the ship in Aqaba.

May 9, The guided-missile destroyer moored at Berth 1, Sultan Qaboos Port in Muscat, Oman, for a four-day port call after participated in a multi-national exercise Khunjar Haad. Transited Strait of Hormuz northbound on May 14.

June 14, USS Truxtun, along with USS George H.W. Bush and USS Philippine Sea (CG 58), transited the Strait of Hormuz northbound. Inport KBSP, Bahrain, again from July 1?-19; Departed Arabian Gulf on July 20; Entered the Red Sea on July 22; Transited Suez Canal northbound (#6), with the USS Norfolk (SSN 714), on July 29.

July 30, The Truxtun moored at West Quay, Passenger Terminal in Limassol, Cyprus, for a four-day port visit. Returned to Red Sea on Aug. 6; Transited Suez Canal northbound (#8), with the USS Annapolis (SSN 760), on Aug. 1?; Inport Aqaba again from Aug. 19-23; Transited Suez Canal northbound (#10) on Aug. 31; Returned to Red Sea on Sept. 2; Entered the Arabian Gulf on Sept. 2?.

November 1, USS Truxtun moored to a buoy off the coast of Villefranche-sur-Mer, France, for a three-day port visit. Transited the Strait of Gibraltar on Nov. 6.

November 15, USS Truxtun returned to Naval Station Norfolk after a nine-month deployment in the U.S. 5th and 6th Fleet AoR.

December 30, Marine Hydraulics International, Inc., Norfolk, Virginia, was awarded a $7,1 million modification to a previously awarded contract (N00024-10-C-4405) for the USS Truxtun's Selected Restricted Availability (SRA). Work is expected to be completed by June.