Asthma May Raise Risk of Diabetes, Heart Disease

March 21, 2011 -- Asthma may increase your risk of developing diabetes and heart disease, shows new research presented at the annual meeting of the American Academy of Allergy, Asthma & Immunology in San Francisco.

The common denominator between these conditions appears to be inflammation, according to researchers led by Young J. Juhn, MD, MPH, of the Mayo Clinic in Rochester, Minn.

Specifically, the diabetes rate in people without asthma was 104 per 100,000 people compared to 138.4 per 100,000 people among those with asthma. For heart disease, the rate in people without asthma was 134 per 100,000 people vs. 188.6 per 100,000 among those participants with asthma.

“While it’s important for clinicians to be aware of the increased risks of coronary artery disease and diabetes in asthmatics, these findings should be interpreted cautiously given the preliminary nature,” Juhn says in a news release. “Given the significant proportion of people affected by asthma, we need to continue to carefully monitor the potential impact of asthma epidemiology on the epidemiology of other chronic diseases.”

“The link with COPD and diabetes is bolstered by a link between smoking and diabetes and a theoretical link between the concept that an underlying systemic inflammation leads to both COPD and diabetes,” he says.

What’s more, “the extensive use of corticosteroids in COPD may unmask early or unsuspected diabetes,” he says.

These factors may also play a role in the proposed asthma-diabetes link he says, adding that the rate of smoking among people with asthma is higher than one would anticipate.