This forces you to remember the exact version of the assembly as well as the public key token. If you’re worried about a nefarious individual gaining access to your machine and infecting your ado.net assemblies, continue to use the recommended method.

A simpler mechanism is using “LoadWithPartialName” where powershell will load the v4.5 ado.net driver for SQLAnywhere if it is in the Global Assembly Cache (GAC):