Several doctors vie to be the hospital's new ambassador. Meanwhile, April works on an emergency case; a transgender teenage couple arrive at the hospital; and the staff find it difficult to adhere to some exasperating new policies.

Jackson's mom tries to persuade him to relocate to Boston. Meanwhile, the doctors talk to a potential investor about saving the hospital; the interns think their jobs are in jeopardy; and Alex's attentiveness to a patient wins him points with Jo.