At a Tokyo Afghan donor's conference, Clinton barely stopped short of declaring war. Time is running out to save Syria, she told reporters.

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Kofi Annan's admission about peace failing is a "wake-up call for everyone."

"The sand is running out of the hourglass."

"It should be abundantly clear to those who support the Assad regime their days are numbered."

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"The sooner there can be an end to the violence and a begetting of a political transition process, not only will fewer people die, but there's a chance to save the Syrian state from a catastrophic assault that would be dangerous not only to the country, but the region."