Alveolar Dead Space as Predictor of Organ Failure in Severe Sepsis

Verified May 2016 by Rosa Estrada Y Martin, The University of Texas Health Science Center, Houston

Sponsor:

The University of Texas Health Science Center, Houston

ClinicalTrials.gov Identifier:

NCT01315782

First Posted: March 15, 2011

Last Update Posted: May 13, 2016

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This is an observational study to understand the changes in alveolar dead space in medical critically ill patients with severe infection (severe sepsis) requiring mechanical ventilation and the possibility to predict multi-organ failure.

The measurement of alveolar dead space used to require sophisticated equipment and time. New ventilators have microprocessors that allow rapid mathematical calculation with minimal intervention.

The patient will be followed during their ICU stay up to two weeks while on mechanical ventilation.

Patient will be followed daily for the initial 48 hours and then once per week for 2 weeks while mechanically ventilated.

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