Additional files

Additional file 1:

Complete characteristics of study subjects analyzed for cytokines and clinical chemistry. An expanded set of groups was analyzed for age, gender, duration of illness, and
major signs. Corresponding odds ratios are shown, and asterisks (*) indicate significance
at the 5% level.

Map of West Africa displaying calculated rates of LASV Ag, IgM, IgG, and dual antibody
in sera samples obtained from Sierra Leonean Districts of Moyamba and Bombali. (A) Districts of Sierra Leone: the historically hyperendemic districts of Kenema
and Kallahun are circled in blue, and the Northern and Southern districts of Bombali
and Moyamba are underlined in red. A map outlining Sierra Leone's four provinces is
shown in (B). The relative locations in Sierra Leone where panels of normal sera study
samples were collected are boxed in red. Antigen and immunoglobulin rates for locations
sampled in this study are outlined in insets. Numbers of sera analyzed from each region
are noted (N). Serological evidence of LF has been reported in Senegal and Mali (denoted
with solid blue circles), and outbreaks are commonly reported in endemic regions of
Sierra Leone, Guinea, and Liberia (denoted with solid red circles). The relative sub-Saharan
geographical boundary for LF is outlined by the thick transparent orange line dissecting
Guinea and Southern Mali [17]. Source of maps: A. and B. http://commons.wikimedia.org/wiki/Atlas_of_Sierra_Leonewebcite; C. Google maps.