Proton in vivo Magnetic Resonance Spectroscopy(MRS)study on occipital lobe was performed on alcohol dependents and
healthy controls to look for the metabolic aberrations underlying the visual
information processing deficits observed in alcohol dependents as assessed by
PGIBBD(PGI-Battery of Brain Dysfunction).A significant reduction in NAA/Cr
and Glx/Cr ratios and a significant increase in Cho/Cr and Ins/Cr ratios was
observed which could possibly account for impaired visual skills (as
indicated by higher dysfunction rating scores) in alcohol dependents.