NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents
used to treat patients with cancer or conditions related to cancer. Each drug entry
includes links to check for clinical trials listed in NCI's List of Cancer Clinical
Trials.

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The magnesium salt form of the saponin, isoglycyrrhizinate, a derivative of glycyrrhizic acid extracted from the roots of the plant Glycyrrhiza glabra, with potential anti-inflammatory, antioxidant and hepatoprotective activities. Although the exact mechanism of action remains to be fully elucidated, magnesium isoglycyrrhizinate may prevent or reduce hepatotoxicity through the scavenging of free radicals. This agent also modulates the activity of hepatic enzymes such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), superoxide dismutase (SOD) and glutathione peroxidase. Check for active clinical trials using this agent. (NCI Thesaurus)