She lost her right eye and suffered serious head and facial injuries after crashing into a stationary truck during a Marussia test event in June 2012.

In another statement released Saturday, her family said her death was linked to the accident.

"Maria left us while she was sleeping, approximately at 6 a.m., as a consequence of the neurological injuries that she suffered in July of 2012, according to what the forensic doctor has told us," her sister, Isabel, said.

"Maria is gone, but she has left us a very clear message of joy and hope, which is helping the family move on in these moments."

The F1 community, in Japan for Sunday's grand prix at the Suzuka Circuit, flocked to pay its respects to the former World Touring Car Championship and Euroseries 3000 driver.

"We'd like to echo the thoughts of the whole paddock and express our deepest condolences on the news of Maria de Villota's passing. RIP," added Caterham, while Sauber said,"We are shocked to hear about the death of Maria de Villota.

"Our sincerest condolences and sympathy to her family for this tragic loss."