Activated Müller Glia

Friend of Webvision, Peter Westenskow in the Friedlander Laboratory sent us this beautiful image of activated Müller glia in a stressed mouse eye. You can see the scar in the photoreceptor layer towards the top of the image. The mouse line is VLDLR -/-. These mice exhibit aberrant neovascular tufts that invade the ONL and eventually grow into the RPE cells. The red staining is pan-cadherin.