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Periodic CT scans in early stage testicular cancer could prove risky for elders. The scanning itselfcould trigger secondary cancers, warn UC Davis cancer researchers. Physicians should tell the patients of the risk in confining to surveillance instead of opting for lymph noderemoval,the researchers say in their report published online last week in the journal Cancer. Along with a multi-disciplinary team of UC Davis researchers, Karim Chamie, a UC Davis urology resident at the ...

Researchers have discovered genetic pathways to curb kidney cancer cells. Two separate studies indicate that both rare and common cases of kidney cancer may be susceptible to a new class of drugs that inhibits cancer cells from generating the energy needed to survive.
In one study, by researchers at UT Southwestern Medical Center available online and scheduled for the May 5 issue of the journal iOncogene/i, researchers found that inactivating the gene von Hippel-Lindau (VHL) ...

A study published online March 30 in the iJournal of the National Cancer Institute /i says that breast cancer patients who become resistant to tamoxifen may have low levels of a protein called Rho GDI-alpha.
Women whose tumors have estrogen receptors (ERs) often take tamoxifen after surgery to prevent recurrence of the cancer and keep it from metastasizing to other parts of the body. Some patients, however, become resistant to the drug even though their tumors remain ER-positive....

Professor Tessa Holyoake from the University of Glasgow will discuss a brand new approach to treating chronic myeloid leukaemia (CML) in which a small number of cancer cells persist despite effective therapy thus preventing cure while speaking at the UK National Stem Cell Network conference in York later today (31 March).
CML is a type of blood cancer caused by the infamous "Philadelphia Chromosome" genetic abnormality. It is usually treated using a class of drugs called Tyrosine Kin...

Research indicates that stem cells in the intestine, which when they mutate can lead to bowel cancers, might also be grown into transplant tissues to combat the effects of those same cancers. It will be presented at the UK National Stem Cell Network (UKNSCN) annual science meeting will hear today.
Professor Nick Barker of the Institute of Medical Biology in Singapore will explain how he and his team identified that the stem cells which are crucial to maintaining a healthy intestine a...

Findings from a new UCSF study indicate that an experimental drug lessens symptoms of a rare form of childhood leukemia and offers significant insight into the cellular development of the disease.
The mouse model research could spearhead the development of new leukemia therapies and paves the way for future clinical trials in humans.
"Although this drug did not produce a cure, it alleviated the symptoms of leukemia as long as the treatment was continued and delayed the d...

Interventional radiologists have been the leaders in the use of intra-arterial yttrium-90 radioembolization, since its introduction in 2000, to treat liver cancer. Now, new results from a large multi-institutional study show that treating liver tumors with higher doses of Y-90 than previously tried is safe, provides results when chemotherapies have failed, preserves the patient's quality of life-and can be done on an outpatient basis. This study, presented by researchers at the Society of Interv...

Researchers at the Scripps Research Institute have developed a model of how a powerful DNA repair complex works - a finding that may give hope to various treatment of disorders ranging from cancer to cystic fibrosis.
They said that the complex's motor molecule, known as Rad50, is a surprisingly flexible protein that can change shape and even rotate depending on the task at hand.
The finding solves the long-standing mystery of how a single protein complex known as MRN (Mre...

Previous research has indicated that most women face only a small risk of breast cancer coming back after they complete their treatment.
Yet a new study from the University of Michigan Comprehensive Cancer Center finds that nearly half of Latinas who speak little English expressed a great deal of worry about recurrence.
"Some worry about cancer recurrence is understandable. But for some women, these worries can be so strong that they impact their treatment decisions, sym...

Scientists at the University of Colorado Cancer Center have identified an enzyme that could be used to diagnose colon cancer earlier.
It is possible that this enzyme also could be a key to stopping the cancer.
This enzyme biomarker could help physicians identify more colon cancers and do so at earlier stages when the cancer is more successfully treated.
The research was conducted under the leadership of Vasilis Vasiliou, professor of molecular toxicology at t...