Systems Biology Center New York

Teaching Resources

Systems Biology—Biomedical Modeling

Members of the Systems Biology Center New York developed a course at Icahn School of Medicine that introduces first-year graduate students to computational principles and approaches. There are a total of 13 Teaching Resources published in sequential issues of Science Signaling. Each of the Teaching Resources provides lecture notes, slides, problem sets, and answer keys.

Training in Systems Pharmacology: Predoctoral Program in Pharmacology and Systems Biology at Icahn School of Medicine

Abstract: Our recently developed predoctoral training program in pharmacology and systems biology prepares students to become experts in systems-level models of disease that identify therapeutic targets and predict adverse effects or new uses of existing therapeutics. Multiple computational modeling modes are introduced throughout a curriculum that integrates basic cell and molecular sciences with the physiology and pathophysiology of disease states. Problem-based learning exercises enable students from different experimental and computational backgrounds to design experiments and interpret data quantitatively.

Using Web-Based Discussion Forums as a Model of the Peer-Review Process and a Tool for Assessment

Abstract: This Teaching Resource describes how to use an online asynchronous discussion as a mechanism to introduce students to the peer-review process, as well as to assess student performance and understanding. This method was applied to a graduate course on signal transduction and the Teaching Resource includes a syllabus, detailed plan for incorporating the online discussion, sample journal club questions, and sample student responses to the discussion forum, faculty responses, and student revisions.

Abstract: This course uses the primary literature to develop a systems-level understanding of the information flow through the various cell signaling pathways and networks. Current areas of research activities in the experimental and theoretical understanding of cell signaling research are highlighted. This Teaching Resource describes a sample syllabus and organization for this course. Each lecture is 2 hours. After each set of lectures, there is a 2-hour discussion period during which students present an in-depth analysis of a primary literature article, selected in consultation with the lecturer.