Intestinal-Type Adenocarcinoma: Classification, Immunophenotype, Molecular Features and...
Leivo, Ilmo
2017-03-20 00:00:00
Intestinal-type adenocarcinoma is the second most frequent sinonasal adenocarcinoma. High incidence of these tumors is seen among workers with occupational wood dust exposure, particularly of hardwood dusts. Intestinal-type adenocarcinoma has striking histomorphologic and immunophenotypic similarities with colorectal adenocarcinomas, but on the level of molecular pathologic mechanisms these tumors have their own specific features different from gastrointestinal tumors. This article provides an update on current histopathologic classification of intestinal-type adenocarcinomas, their immunophenotypic properties, recent advances in molecular pathologic features and differential diagnostic considerations.
http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.pngHead and Neck PathologySpringer Journalshttp://www.deepdyve.com/lp/springer-journals/intestinal-type-adenocarcinoma-classification-immunophenotype-mwCtXcmhxv

Abstract

Intestinal-type adenocarcinoma is the second most frequent sinonasal adenocarcinoma. High incidence of these tumors is seen among workers with occupational wood dust exposure, particularly of hardwood dusts. Intestinal-type adenocarcinoma has striking histomorphologic and immunophenotypic similarities with colorectal adenocarcinomas, but on the level of molecular pathologic mechanisms these tumors have their own specific features different from gastrointestinal tumors. This article provides an update on current histopathologic classification of intestinal-type adenocarcinomas, their immunophenotypic properties, recent advances in molecular pathologic features and differential diagnostic considerations.

Journal

Head and Neck Pathology
– Springer Journals

Published: Mar 20, 2017

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