Pharmacokinetics

Pharmacokinetic (PK) studies are a key aspect of the drug development process. Knowing how the body absorbs, distributes, metabolizes and eliminates drugs helps guide the dosing regimen to maximize efficacy and avoid undesirable effects. Explora has established protocols to handle a wide array of PK study designs. Our goal is to achieve rapid turnaround with quality results for a reasonable cost.

Drug Administration Routes:

Study Design can include the following:

Single or repeat dose administration

Continuous infusion

Tissue collection with or without perfusion to determine biodistribution

Biodistribution using radiolabeled compounds

Bioanalysis:

Explora has established strong working relationships with reputable bioanalytical companies to efficiently process and analyze samples from our PK studies. We can manage the entire study from drug to report, with a rapid turnaround time and high quality results.

Did you know?

Commonly administered prescription drugs have a wide range of biological half-lives. For example, the vasopressor norepinephrine has a half-life of less than 2 minutes, whereas bedaquiline, used to treat drug-resistant tuberculosis, has a half-life of over 5 months.