This is a surprisingly tepid horror/thriller, considering all the hoopla it received before it was released. The premise is that two FBI agents (one of them Samuel L. Jackson) are escorting a witness on a plane from Hawaii to Los Angeles, but the guy he is going to testify against has his henchmen put a bunch of poisonous snakes on the plane. Once the plane is a few hours in the air the reptiles are released from their cages and exposed to a pheromone that makes them crazy. They then go about biting anything and everything on the plane, much to the dismay of the passengers.

I'm not a big fan of computer animated creatures and here is another example where the snakes look like cartoons, not real creatures. Samuel L. Jackson and Juliann Margulies (ER, GHOST SHIP) are vastly under-utilized and if they weren't headlining this movie this would have simply been another crazy animal movie premiering Saturday night on the Sci-Fi Channel. The direct-to-video movie TAIL STING (2001), which has the exact same premise but with giant, genetically mutated scorpions on a plane, is far more entertaining.