Uses of Zepdyl (10/4 mg) Syrup

What is it prescribed for?

Commonly asked questions

The effect of this medicine can be observed within 30 minutes of administration of the dose.

How long do the effects of this medicine last?

The effect of this medicine lasts for an average duration of 4 to 6 hours.

Is it safe to consume alcohol while taking this medicine?

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, fainting, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.

Is this a habit forming medicine?

This medicine may be habit-forming in some cases, especially after prolonged use.

Can this medicine be taken during pregnancy?

This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Can this medicine be taken while breast-feeding?

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

When not to use?

Allergy

This medicine is not recommended for use in patients with a known allergy to codeine, chlorpheniramine, or any other inactive ingredients present along with these medicines.

Respiratory depression

This medicine is not recommended for use in patients with respiratory depression, in the absence of resuscitative equipment, due to the increased risk of worsening of the patient's condition.

Acute or severe bronchial asthma

This medicine is not recommended for use in patients with acute or severe bronchial asthma, in the absence of resuscitative equipment, due to the increased risk of worsening of the patient's condition.

Monoamine oxidase inhibitors (MAO)

This medicine is not recommended for use in patients receiving Monoamine oxidase inhibitors (MAO) due to the increased risk of serious adverse effects.

Paralytic ileus

This medicine is not recommended for use in patients with gastrointestinal obstruction, including paralytic ileus due to the increased risk of worsening of the patient's condition.

Benign prostatic hyperplasia

This medicine is not recommended for use in patients with benign prostatic hyperplasia (enlarged prostate) since it may cause increased difficulty in passing urine.

Warnings

Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

General warnings

Acute alcohol intoxication

This medicine is not recommended for use in patients with acute alcohol intoxication exhibiting depressed vital signs due to the increased risk of severe respiratory depression and death. Replacement with a suitable alternative should be considered under your doctor's supervision.

Drug dependence

This medicine has the potential to cause drug dependence and abuse. This risk is especially higher if the medicine is used for a prolonged period of time. Patients should be monitored closely for any change in mood and behavior during treatment with this medicine. Abrupt discontinuation is not recommended since it may cause withdrawal symptoms. Withdrawal of therapy should be done gradually with close monitoring of the patient.

Intracranial pressure

This medicine should be used with caution in patients with head injury or intracranial lesions since it may elevate the intracranial pressure and worsen the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Epilepsy

Caution is advised while using this medicine in patients with epilepsy since it increases the risk of seizures. Report any unusual symptoms to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Hepatic and/or renal impairment

Caution is advised while using this medicine in patients with liver/kidney disease due to an increase in the risk of adverse effects in these patients. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Driving or operating heavy machinery

It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating heavy machinery while receiving this medicine since it increases the risk of symptoms such as drowsiness, dizziness, impaired thinking, etc.

Infectious diarrhea

This medicine should be used with caution in patients with infectious diarrhea due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Use in geriatrics

This medicine should be used with caution in the elderly patients due to the increased risk of severe adverse effects. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Use in pediatrics

This medicine is not recommended for use in patients less than 12 years of age. For adolescent patients, it should be used with extreme caution due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Dosage

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, fainting, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.

Interaction with Medicine

Aripiprazole

Linezolid

Anxiolytics

Monoamine oxidase inhibitors

Ramelteon

Alvimopan

Disease interactions

Hypotension

This medicine should be used with caution in patients with a known history of hypotension due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Hypothyroidism

This medicine should be used with caution in patients with hypothyroidism due to the increased risk of respiratory depression and prolonged CNS depression. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Seizure disorders

This medicine should be used with caution in patients with seizure disorders due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Arrhythmias

This medicine should be used with caution in patients with Arrhythmias due to the increased risk of bradycardia (a slow heart rate) and worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Asthma

Use of this medicine in patients with asthma/COPD is not recommended since it may increase the risk of further lung problems such as respiratory tract blockage. This risk is especially higher in the elderly patients. Replacement with a suitable alternative should be considered under your doctor's supervision.

Food interactions

Information not available.

Lab interactions

Information not available.

This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take this medicine with or without food. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.

Other details

Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works

Codeine works by changing the way the brain and nervous system respond to pain. It also acts on the part of the brain responsible for coughing. Chlorpheniramine blocks the action of certain substances produced by the body which induce allergic reactions such as a cough. Their combination is thus effective in the treatment of a dry cough.

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Information on this page was last updated on 21 May 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.