NOTE: WE ARE EXPERIENCING HIGH VOLUMES THAT CAN DELAY SHIPPING: Holidays may affect duration of shipping time.

International Shipping Policy

We offer online ordering for shipments going
to the United States, Canada and Australia.
For international orders, call customers
service at 888-242-5327 to place your order.

NOTE: Metabolic Maintenance is not responsible for additional duties, taxes, import licensing or product seizures. Please check with the appropriate authorities in your country to determine local regulations.

Please contact Customer Service to initiate a return.

All products being returned must be unopened.

We only accept returns on products purchased directly from our company .

Returns must be authorized within 5 days of receiving product.

No returns after 35 days from the date of purchase.

Authorized returns are subject to a 15% restocking fee.

Custom products are non-refundable.

We only accept returns for product purchased directly through our website.

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SAMe Description

Naturally occurring in our bodies, SAMe is one versatile molecule. It is used as a critical methyl donor throughout the body aiding in cellular protection. SAMe crosses the blood-brain barrier and contributes to the formation of dopamine, serotonin and norepinephrine, supporting balanced mood. It has also been shown to promote healthy joint function and liver health. Though versatile and effective, the molecule can be less stable. Our form combines SAMe with calcium making it less sensitive to humidity and temperature. This means you can get the benefits of SAMe without ingesting the chemicals involved in a coated tablet or hassling with refrigeration. To promote maximum efficacy, we provide our clean version of SAMe in acid resistant capsules for release in the intestine.

Promotes positive mood*

Improves brain function*

Supports healthy joints*

Stable, acid-resistant capsules

*These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

Description: SAMe, a metabolite of the amino acid L-methionine, is present in all cells of the body. It plays a crucial biochemical role as a methyl donor in the synthesis of neurotransmitters, nucleic acids, phospholipids and proteins.

Uses: 1) Mood and brain health. SAMe has been extensively researched for its ability to promote positive mood and emotional balance. SAMe-dependent methylation reactions are vital for the synthesis monoamine neurotransmitters: dopamine, serotonin, epinephrine, and norepinephrine. The networks of neurons that utilize monoamine neurotransmitters are involved in the regulation of cognitive processes such as emotion, arousal, and certain types of memory. SAMe is also needed for phosphatidylcholine production which is vital for cell membrane fluidity and central nervous system function.

2) Joint health. SAMe has been shown to promote joint comfort. Evidence suggests SAMe increases production of proteoglycans- proteins found in connective tissue. SAMe may also reduce inflammatory mediators.

3) Liver health. SAMe methyl groups contribute to the fluidity of liver lipid membranes. Methylation is an important Phase II detox pathway. SAMe has been shown to improve liver function as measured by standard liver tests and to increase hepatic glutathione levels.

Acid-resistant capsules protect SAMe from the low pH of the stomach and deliver it to the small intestine where it is absorbed. Metabolic Maintenance uses SAMe stabilized with calcium made by Gnosis-Bio in Italy. It does not require refrigeration or coatings.

Source Materials: SAMe and L-leucine are made by fermentation. Calcium and magnesium are mined minerals. Cellulose for capsules is derived from softwood tree pulp. Gellan gum for acid resistant capsules is made by fermentation with Pseudomonas elodea. All ingredients are vegan and non-GMO.

Allergens: According to information provided by our suppliers, these capsules are free of the eight major allergens as identified by the Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA): Wheat (gluten), eggs, milk, soybeans, shellfish, fish, peanuts, tree nuts.

Recommendations: One to two (1-2) capsules daily, between meals, or as directed by a healthcare professional.

Precautions: Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement. If you suffer from bipolar (manic) depression, do not use this product.

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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The information contained herein is for informational purposes only and does not establish a doctor-patient relationship. Please be sure to consult your physician before taking this or any other product.

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