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PRAL Timeline: Proof Of Concept Years

Proof Of Concept Years is first in my series, Potential Renal Acid Load Timeline. So this timeline follows published food research showing how Remer and Manz developed PRAL.

In future PRAL timelines, you will see how PRAL has become the world standard for measuring Alkaline Diets. Then you will see how useful PRAL is for many diseases. Because it can be used as an assessment tool during diagnosis. Also, PRAL can help measure treatment progress where diet is strongly linked to a disease.

Please note that this is not a practical healthy eating help series. Because I want to establish the scientific facts of alkaline diets now. Then I will bring you practical eating plans and nutrition advice for many different diseases. So I can send you a brief summary email when I publish more. If you want to stay informed about healthy eating subscribe:

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Because urine pH is a relevant risk factor in most types of urinary stone disease, a dietetic manipulation of renal hydrogen ion excretion would be advantageous for a number of individuals at risk. Also, patients with poorly functioning kidneys in whom metabolic acidosis is a common manifestation of an impaired renal capacity to excrete the daily produced acid could benefit from specific dietetic means that reduce daily acid load.

The urinary calcium excretion of renal stone formers seems to be dependent on dietary acid load rather than dietary calcium intake. In patients consuming an acidifying diet, a restriction of calcium intake could increase bone resorption leading to a progressive bone loss.

2001 October

In the new physiologically based terminology of systemic acid-base status, the relationship between blood acid-base status and net acid intake or excretion was, however, incorrectly simplified. In the 1970s metabolic acidosis was observed in patients on chemically defined diets and parenteral nutrition.

Notes: Manz takes a swipe at the denialists who stick with outdated estimates of kidney acid load. Unfortunately, it isn’t recognized widely enough. Because the old concepts are still being used to promote poor nutrition advice.

Your PRAL Timeline

I wonder what Potential Renal Acid Load means to you. Are you just discovering this modern standard? Or are you excited to improve your health with an alkaline diet based on PRAL? Please share your PRAL questions, experiences, and opinions in the Feedback Form below.

Health Disclaimer: The purpose of Foodary is to help you understand how food affects health.

Information is provided by a layman (Keith Taylor), with no medical training or qualifications. It should not be used for diagnosing or treating any health problem or disease.The information is given to help you understand your doctor's advice and know what questions to ask. It is not a substitute for professional care. If you have an actual or suspected health problem, you should consult your doctor.