Up until his retirement, Mayweather was the reigning lineal, WBC, WBA (Super) and The Ring welterweight champion, as well as the lineal, WBC, WBA (Super) and The Ringlight middleweight champion. Since retiring, he has vacated all but two of these titles. Many sporting news and boxing websites rated Mayweather as the best pound for pound boxer in the world for almost ten years, including The Ring, Sports Illustrated, ESPN, BoxRec, Fox Sports, and Yahoo! Sports.[9][10][11][12][13][14] Mayweather topped the Forbes and Sports Illustrated lists of the 50 highest-paid athletes of 2012 and 2013, and the Forbeslist again in 2014 and 2015, listing him as the highest paid athlete in the world . In 2007, He founded Mayweather Promotions, his own boxing promotional firm after defecting from Bob Arum's Top Rank.

He has a record of 26–0 (10 knockouts) in world title fights, 23–0 (9 KOs) in lineal title fights, 24–0 (7 KOs) against former or current world titlists, 12–0 (3 KOs) against former or current lineal titles, and 2–0 (1 KO) against International Boxing Hall of Fame inductees.