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Following her revelation that the actor James Woods allegedly hit on her when she was just 16, Amber Tamblyn has written a searing essay for The New York Times, exploring sexism in the entertainment industry.

Tarana Burke speaks at the March to End Rape Culture in Philadelphia on Sept. 28, 2014.(Photo: Alex J. Udowenko)

From influential U.S. senators to grassroots activists, the speakers at the first national convention of the Women's March are a powerful group.

Consider Tarana Burke, who created the original "Me Too" movement more than a decade ago. Her concept of empowerment through empathy became a Web rallying cry in October when women began using #MeToo on social media to show how prevalent sexual harassment and abuse is.

On Wednesday night, news broke that actress Rose McGowan would be giving opening remarks Friday and joining a panel discussion titled Fighting for Survivors of Sexual Assault in the Age of Betsy DeVos."

In the wake of numerous sexual harassment and abuse accusations against entertainment industry figure Harvey Weinstein, McGowan and her new #RoseArmy effort has emerged as an outspoken advocate for women.

Burke and McGowan will be among the voices heard during the Women's Convention, which runs Friday through Sunday in Detroit and is expected to draw an estimated 4,000 attendees.

The speaker list reflects the wide, inclusive range of speakers -- the first such convention for women in 40 years.

Three movers and shakers from the U.S. Senate -- Michigan's Debbie Stabenow (the opening night speaker), Minnesota's Amy Klobuchar and New York's Kirsten Gillibrand -- are schedule to be there.

This photo taken Jan. 21, 2014 shows Sen. Kirsten Gillibrand, D-N.Y., chair of the Senate Armed Services subcommittee on Personnel, discussing her proposed reforms for prosecuting sexual assaults in the military, during an interview with The Associated Press in her Capitol Hill office in Washington. An Associated Press investigation into the militaryâ€™s handling of sexual assaults in Japan has found a pattern of random and inconsistent judgments in which most offenders are not incarcerated. Instead, commanders have ordered â€œnonjudicial punishmentsâ€ that ranged from docked pay to a letter of reprimand. (AP Photo/J. Scott Applewhite)(Photo: J. Scott Applewhite, AP)

Both Klobuchar and Gillibrand have been mentioned by pundits as possible presidential contenders for 2020.

Also representing the political realm are U.S. representatives including California veteran Maxine Waters to Michigan's own Brenda Lawrence and Debbie Dingell.

Detroit City Council member Mary Sheffield will be there, along with former Michigan state legislator Rashida Tlaib and Michigan gubernatorial candidate Gretchen Whitmer.

The city of Flint will be represented by Mayor Karen Weaver, and a national media phenomenon, kid activist Mari Copeny (aka Little Miss Flint).

Hollywood will be a presence. Amber Tamblyn, formerly of "House" and "Two and a Half Men" and films like "127 Hours," will be talking about issues important to her.

Actress Amber Tamblyn.(Photo: Diane Bondareff/Invision/AP)

In a personal account of sexual harassment in Hollywood was published in the New York Times in September, Tamblyn denounced the way society dismisses women's reports of their sexual abuse, assault and harassment, drawing attention to why women so often don't speak up.

Actress Piper Perabo, known for her Golden-Globe nominated performance on the USA drama "Covert Affairs" and the movie "Coyote Ugly," is also making the trip. She's an advocate for the International Rescue Committee, a global humanitarian relief organization.

Flint Mayor Karen Weaver speaks to a crowd before President Bill Clinton to speak to supporters during the Michigan Democratic Party Flint Stronger Together Rally at the Northbank Center in downtown Flint on Monday October 3, 2016.(Photo: Ryan Garza, Detroit Free Press)

For information on ticketing, go to the Women's Convention official website. The ticket cost for all three days of the conference is $295 for adults and $125 for students. One-day-only tickets are $125 for Friday and Saturday and $75 for Sunday.