GREMLIN Results:
Residue pairs sorted by strength in covariance:Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

i

j

Raw Score

Scaled Score

9_Y

71_A

0.97129

2.080

73_I

87_E

0.96072

2.057

37_Y

41_E

0.93892

2.011

77_K

87_E

0.93712

2.007

87_E

91_N

0.93616

2.005

32_L

79_L

0.92808

1.987

82_P

87_E

0.92628

1.983

17_T

21_F

0.91085

1.950

29_C

39_V

0.89495

1.916

35_D

38_E

0.89393

1.914

84_Q

91_N

0.85947

1.840

10_A

25_L

0.82903

1.775

75_L

78_E

0.82159

1.759

16_A

65_L

0.80594

1.726

38_E

41_E

0.80136

1.716

31_K

81_Y

0.78279

1.676

88_A

91_N

0.77874

1.668

6_L

29_C

0.75228

1.611

76_A

83_P

0.74075

1.586

16_A

69_P

0.73783

1.580

30_E

36_V

0.73403

1.572

74_Y

77_K

0.71945

1.541

70_Y

90_I

0.71858

1.539

74_Y

78_E

0.7067

1.513

14_F

18_K

0.68684

1.471

17_T

89_V

0.65964

1.413

27_R

31_K

0.65871

1.411

28_L

83_P

0.63376

1.357

40_I

44_N

0.61319

1.313

13_A

21_F

0.6076

1.301

47_P

51_P

0.60533

1.296

18_K

22_A

0.55573

1.190

84_Q

87_E

0.55326

1.185

10_A

29_C

0.55126

1.180

3_E

34_I

0.54529

1.168

11_E

43_A

0.54472

1.166

20_A

85_L

0.54011

1.157

75_L

79_L

0.53299

1.141

6_L

34_I

0.52004

1.114

14_F

25_L

0.51261

1.098

70_Y

74_Y

0.5126

1.098

17_T

85_L

0.50838

1.089

27_R

81_Y

0.49768

1.066

24_E

84_Q

0.48948

1.048

13_A

86_L

0.48614

1.041

73_I

77_K

0.48519

1.039

84_Q

88_A

0.47304

1.013

48_R

53_Y

0.4709

1.008

61_G

64_C

0.46616

0.998

6_L

32_L

0.46526

0.996

31_K

79_L

0.46305

0.992

29_C

36_V

0.46279

0.991

8_K

12_N

0.45993

0.985

77_K

90_I

0.45579

0.976

47_P

52_H

0.45511

0.975

73_I

90_I

0.45358

0.971

12_N

68_D

0.45333

0.971

69_P

86_L

0.44802

0.959

73_I

83_P

0.44452

0.952

19_I

65_L

0.44405

0.951

28_L

76_A

0.43991

0.942

11_E

15_R

0.4384

0.939

27_R

30_E

0.42627

0.913

66_P

90_I

0.41868

0.897

26_A

40_I

0.41363

0.886

13_A

72_L

0.40719

0.872

20_A

92_I

0.40171

0.860

37_Y

55_R

0.39769

0.852

85_L

88_A

0.39672

0.850

60_F

90_I

0.39012

0.835

7_I

42_A

0.38985

0.835

7_I

38_E

0.38368

0.822

3_E

38_E

0.38112

0.816

16_A

90_I

0.37335

0.799

50_G

53_Y

0.37286

0.798

28_L

75_L

0.36971

0.792

5_E

46_D

0.36675

0.785

48_R

51_P

0.36291

0.777

11_E

46_D

0.36269

0.777

88_A

92_I

0.36172

0.775

38_E

42_A

0.35577

0.762

32_L

75_L

0.34794

0.745

9_Y

72_L

0.34719

0.743

42_A

46_D

0.3434

0.735

14_F

43_A

0.33951

0.727

5_E

11_E

0.32689

0.700

36_V

40_I

0.32434

0.695

10_A

28_L

0.32433

0.695

66_P

70_Y

0.32323

0.692

4_A

11_E

0.32181

0.689

14_F

22_A

0.31987

0.685

12_N

15_R

0.31553

0.676

10_A

14_F

0.31546

0.676

85_L

89_V

0.31314

0.671

70_Y

73_I

0.31214

0.668

10_A

39_V

0.31181

0.668

77_K

82_P

0.31155

0.667

12_N

67_K

0.30779

0.659

24_E

83_P

0.30734

0.658

82_P

91_N

0.30648

0.656

12_N

64_C

0.30456

0.652

3_E

39_V

0.30431

0.652

8_K

68_D

0.30039

0.643

47_P

50_G

0.30002

0.642

37_Y

40_I

0.29872

0.640

60_F

70_Y

0.29454

0.631

53_Y

56_P

0.29401

0.630

7_I

39_V

0.29039

0.622

10_A

75_L

0.28977

0.620

17_T

86_L

0.28836

0.617

77_K

80_G

0.28725

0.615

19_I

64_C

0.28587

0.612

22_A

49_I

0.28564

0.612

41_E

80_G

0.28272

0.605

18_K

54_L

0.28167

0.603

15_R

19_I

0.28047

0.601

64_C

71_A

0.2789

0.597

58_P

64_C

0.27737

0.594

55_R

58_P

0.27643

0.592

79_L

82_P

0.27633

0.592

3_E

6_L

0.27366

0.586

74_Y

84_Q

0.2735

0.586

15_R

46_D

0.26761

0.573

42_A

45_T

0.2674

0.573

70_Y

77_K

0.26719

0.572

7_I

34_I

0.26549

0.569

14_F

21_F

0.26526

0.568

26_A

29_C

0.26074

0.558

20_A

88_A

0.25922

0.555

69_P

89_V

0.25805

0.553

60_F

64_C

0.25626

0.549

24_E

92_I

0.25129

0.538

18_K

21_F

0.25112

0.538

23_N

57_G

0.24962

0.535

Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.

HHsearch Results:
Top (length/2) GREMLIN results overlayed on top 10 PDB hits: Legend: The grey circles underneath are pdb residue contacts (min distance < 5 Angstroms). The coloring of these circles is based on HHsearch results which uses the overall probability, per-site alignment prob and agreement of top hits weighted by HHsearch score (Note we only consider monomeric contacts, there might be homo-oligomeric contacts in the pdb that are not shown.)