50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors (174 aa)

0.796

rplE

50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs (179 aa)

0.771

ksgA

Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3’-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (255 aa)

0.767

rplR

50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (117 aa)

0.754

Mfla_1873

Condensin subunit ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (184 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

Mfla_0184

Mfla_1204

Mfla_0184

Mfla_1204

Sun protein

GTP-binding; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity

0.891

Mfla_0184

ftsJ

Mfla_0184

Mfla_0782

Sun protein

Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2’-O position of the ribose in the fully assembled 50S ribosomal subunit

0.878

Mfla_0184

ksgA

Mfla_0184

Mfla_2152

Sun protein

Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3’-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits

0.841

Mfla_0184

rplE

Mfla_0184

Mfla_0291

Sun protein

50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs

0.709

Mfla_0184

rplJ

Mfla_0184

Mfla_0270

Sun protein

50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors

0.846

Mfla_0184

rplR

Mfla_0184

Mfla_0295

Sun protein

50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance

0.704

Mfla_0184

rpmD

Mfla_0184

Mfla_0297

Sun protein

50S ribosomal protein L30P

0.828

Mfla_0184

truB

Mfla_0184

Mfla_0069

Sun protein

tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs

0.811

Mfla_0208

Mfla_1204

Mfla_0208

Mfla_1204

Fmu (Sun)

GTP-binding; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity

0.902

Mfla_0208

ftsJ

Mfla_0208

Mfla_0782

Fmu (Sun)

Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2’-O position of the ribose in the fully assembled 50S ribosomal subunit

0.919

Mfla_0208

ksgA

Mfla_0208

Mfla_2152

Fmu (Sun)

Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3’-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits

0.771

Mfla_0208

rplE

Mfla_0208

Mfla_0291

Fmu (Sun)

50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs

0.709

Mfla_0208

rplJ

Mfla_0208

Mfla_0270

Fmu (Sun)

50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors

0.846

Mfla_0208

rplR

Mfla_0208

Mfla_0295

Fmu (Sun)

50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance

0.704

Mfla_0208

rpmD

Mfla_0208

Mfla_0297

Fmu (Sun)

50S ribosomal protein L30P

0.828

Mfla_0208

truB

Mfla_0208

Mfla_0069

Fmu (Sun)

tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs

0.797

Mfla_1204

Mfla_0184

Mfla_1204

Mfla_0184

GTP-binding; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity

Sun protein

0.891

Mfla_1204

Mfla_0208

Mfla_1204

Mfla_0208

GTP-binding; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity

Fmu (Sun)

0.902

Mfla_1204

Mfla_1873

Mfla_1204

Mfla_1873

GTP-binding; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity

Condensin subunit ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves

0.754

Mfla_1204

ftsJ

Mfla_1204

Mfla_0782

GTP-binding; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity

Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2’-O position of the ribose in the fully assembled 50S ribosomal subunit

0.882

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: