美国西雅图弗雷德哈钦森癌症研究中心博士后研究员文章来源：知识人网 更新时间：2018年01月22日

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer with minimal side effects. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first and largest cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

The Hutchinson Institute for Cancer Outcomes Research (HICOR), in collaboration with Bayer HealthCare, is seeking applications for a 2-year postdoctoral fellowship in health economics and outcomes research. HICOR is located within Fred Hutch’s Public Health Sciences Division, and is built on the vision of reducing the human and economic burden of cancer for patients, families and society. The HICOR team works to develop and apply innovative scientific methods in health economics, clinical and public health research and data science to enhance value in cancer care and improve outcomes for patients. The interdisciplinary research portfolio includes studies in cost-effectiveness alongside clinical trials, cancer care delivery research, pragmatic clinical trials, financial toxicity and economic burden, methods for comparative- and cost-effectiveness research, and cancer informatics. Bayer HealthCare is among the world’s foremost innovators in the field of pharmaceutical and medical products, and they research, develop, manufacture and market products to improve the health of people.

Responsibilities

We are offering the successful candidate an excellent opportunity to fully participate in the scientific aspects of this portfolio, including research proposal development, data analysis and reporting, manuscript preparation, and participation in national scientific meetings. The first year of the fellowship is conducted at Fred Hutch in Seattle. The objective of the first year is to provide the fellow with the training and experience necessary for conducting pharmacoeconomic research. They will be assigned pharmaceutical economics and general health policy, and taught methods of economic assessment, health services research design, and statistical analyses.

During the first few months of the program, the fellow will choose an individual academic advisor to work with them to design an individualized program to meet their goals. They will meet with their advisor on a regular basis to review progress, discuss work, review and assign current research articles. In addition, they will participate in a research seminar designed to provide them with experience in evaluation, critiquing, preparing, and presenting scholarly research during each quarter of the first year, and will be expected to present a report on their independent research once during the first year.

The fellow will be required to participate in at least one ongoing research project with a member of the faculty and are encouraged to develop, under the supervision of the faculty mentor, at least one research proposal on a Bayer compound to be submitted to Bayer for approval. Research proposals shall be implemented while fellows are at Fred Hutch but may continue into the second year of the program. Research will be managed by the fellow under the supervision of Fred Hutch faculty and Bayer researchers.

During the second year of training the fellow will be part of Bayer’s US Health Economics and Outcome Research team and will conduct an approved pharmacoeconomic study in the therapeutic area of oncology. This part of the program is designed to allow fellows to learn about the role of pharmacoeconomic research in the drug development and evaluation process within the industry setting. The research may be on an existing or experimental oncology product, a therapeutic class of oncology drugs, or an oncology disease state of interest to Bayer.

In addition to completing their individual research project(s), the fellow will participate in ongoing pharmacoeconomic evaluations or other projects assigned by their Bayer preceptor. They will have the opportunity to interact with departments involved in clinical research, commercial development, and regulatory affairs at Bayer to learn how economic analyses are used by the pharmaceutical industry, and will also learn how Bayer uses clinical, epidemiologic and pharmacoeconomic data to support the utilization of its products. The fellow will be expected to present the results of any individual research projects to Fred Hutch faculty, graduate students, and other post-doctoral fellows as well as to their colleagues at Bayer.

The successful candidate will spend twelve months on-site at Fred Hutch in Seattle, Washington followed by twelve months on-site at Bayer HealthCare Pharmaceuticals Inc, located in Whippany, New Jersey.

Qualifications

Eligible candidates will have a medical degree and/or doctoral level degree in economics, health economics, medicine, pharmacy, epidemiology or related subjects. For those holding the MD or PharmD degree, completion of a clinical residency or equivalent experience is encouraged.

Candidates should submit an application consisting of curriculum vitae, a letter of intent, and three letters of recommendation. Two finalists will be invited to an in-person interview at Fred Hutch and/or live or telephone interviews with HEOR leaders at Bayer Healthcare Pharmaceuticals. Travel expenses will be paid from the Bayer Post-Doc budget. Fellows will be selected by a joint committee composed of faculty from Fred Hutch’s HICOR and Bayer Healthcare. Applicants will be advised of results no later than May 2018. Final selection of the selected candidate will made no later than June 2018.