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In over 20 years, Wonderup S.a.g.l. with natural products to its Naturdie-ta line, has grown steadily up the challenges of the market and offering himself as a landmark in the field of natural cosmetics and supplements, with safe and effective formulas from a long experience and continuous research [read more ...]

Reductup Men:

Index

Coleus Forskohlii: ingredient of Reductup Men

The coleus has been used for many centuries as a regulator of blood pressure and certainly the ancient doctors could not know that the molecule also had antiplatelet, anti-inflammatory, bronchodilator and vasodi-lator.

Forskolin has its therapeutic properties to a specific mechanism of action that activates the enzyme adenylate cyclase 4, resulting in increased concentrations of c-AMP in all eukaryotic cells. The c-AMP has a basic function in cellular regulation, exercising a positive effect on cardiova-scular level, pulmonary, skin and platelet aggregation.
Increasing levels of c-AMP in the heart and vessels, forskolin causes a decrease in blood pressure by relaxing vascular smooth muscle and improves left ventricular function, exerting a positive isotropic effect.

At the pulmonary level, the increased levels of c-AMP caused by forskolin provides a relaxation of bronchial smooth muscles and relief of asthma symptoms.
Another area of implementation of forskolin is the psoriasis. Similarly asthma, psoriasis is also characterized by low levels of c-AMP in the dermis. This alteration contributes to the accelerated replacement of mitotic keratinocytes caused the clinical disease.

In this regard there is evidence of improvement in psoriasis symptoms with forskolin that regulating the concentration of c-AMP and can exert a positive effect on the disease, optimizing the turnover cheatinocitarius.
The modern scientific analysis has shown that the potential applications of the extract of coleus forskohlii are numerous because the molecule has a mechanism of action and properties that permit use as an adjuvant in numerous systemic diseases.