Two officers at the scene of the second of two collisions involving a driver police say was high Tuesday. (Photo by Christine Dempsey/Hartford Courant)

A driver who police said was high on PCP struck a bicyclist in downtown Hartford early Tuesday, then sped away and crashed into a school bus, injuring a total of six people — the bicyclist and five students.

The bicyclist was wearing a helmet but still suffered serious injuries, police said.

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The car’s driver, Josmary Rodriguez, 38, of East Street in New Britain, was arrested. She took off on foot after the school bus crash, running three blocks to a methadone clinic, police said, leaving one of her shoes in the middle of Main Street. Officers took her into custody.

The stretch of Main Street between Gold and Wells streets was closed throughout the morning commute while police investigated. The street was reopened shortly after 9:30 a.m.

The two collisions happened on the stretch of Main Street between Gold and Wells streets. (Photo by Christine Dempsey/Hartford Courant)

According to police, the Hyundai Sonata driven by Rodriguez struck the bicyclist about 6:40 a.m., before dawn, near the intersection of Main and Gold streets. The bicyclist rolled onto the hood of the car and hit the ground, Assistant Chief Rafael Medina said.

The driver continued south on Main, slamming into the small school bus in front of the Metropolitan District, 555 Main St., a block away and across the street from Hartford City Hall. Leaving a slider-style sandal in the road, the woman ran three blocks to a methadone clinic near Buckingham Street, where police caught up with her, Medina said.

The bicyclist was rushed to Hartford Hospital. Five teenage students were taken to the Connecticut Children’s Medical Center to be checked for minor injuries that included whiplash, police said.

Rodriguez was charged with driving while under the influence, reckless driving, evading responsibility, operating without a license and interfering with police.