Active Ingredient

Description

Amoxicillin is an Aminopenicillin, which has a broad spectrum of bactericidal activity. Clavulanic Acid is a beta-lactamase inhibitor, used to prevent Amoxicillin’s degradation and to extend its spectrum.

Advent® DT is also indicated for prophylaxis of infections which may be associated with major surgical procedures such as gastrointestinal, pelvic, head and neck, cardiac, renal, joint replacement and biliary tract.

MOA (mechanism of action):

Amoxicillin destroys bacterial cell wall by preventing the synthesis of a substance called peptidoglycan, vital for bacteria's survival. Clavulanic Acid in its turn deactivates a beta-lactamase enzyme produced by some bacteria to hinder the action of Amoxicillin.

For children between 7-12 years old: one and a half tablet (each tablet contains Amoxicillin 200 mg and Clavulanic Acid 28,5 mg) one time in 12 hours.

For children between 2-7 years old: one tablet (each tablet contains Amoxicillin 200 mg and Clavulanic Acid 28,5 mg) each time, one time in 12 hours.

For children between 9 months to 2 years old: half a tablet (each tablet contains Amoxicillin 200 mg and Clavulanic Acid 28,5 mg) one time in 12 hours.

For infants with immature renal function Advent® DT is not recommended.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose of Advent® DT to compensate the missed dose.

Overdose

If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store the reconstituted suspension in the refrigerator below 25 degrees C (77 degrees F). Throw away any unused reconstituted suspension after 7 days. Any extra portion left to be thrown away. Keep out of the reach of children.

Safety Information

Side effects

The most common side effects of Advent® DT are:

antibiotic-associated diarrhoea

indigestion

nausea

vomiting

antibiotic-associated colitis

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Advent® DT if you are allergic to Amoxicillin or any other antibiotic of the Penicillins.

Do not take Advent® DT if you are allergic to Clavulanic Acid or any other ingredients comprised in Advent® DT.

Do not take Advent® DT if you have a history of severe allergic reactions associated with using antibiotics.

Do not take Advent® DT if you are allergic to Nitroimidazole and its derivatives.