Application Information: CX3CR1 antibody

IHC-Fr: Use at a dilution of 1/100 - 1/500. IP: Use at a dilution of 1/300 - 1/800. WB: Use at a dilution of 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.

Form Supplied

Liquid

Concentration

1
mg/ml
(Please refer to the vial label for the specific concentration)

Purification

Protein A purified

Specifications: CX3CR1 antibody

Full Name

chemokine (C-X3-C motif) receptor 1

Background

Fractalkine, also termed neurotactin, is a membrane-bound CX3C chemokine (ref 1). HumanCX3CR1, also named V28, was first cloned from human genomic DNA libraries (ref 2). A G-protein-coupled seven-transmembrane domain receptor, it was recently identified to serve as fractalkine receptor (ref 3). V28 has been shown to mediate both the adhesive and migratory functions of fractalkine. Fractalkine and CX3CR1 represent new types of leukocyte trafficking regulators.