Bowie scored his first hit single on the Billboard Hot 100 chart in 1972 with “Changes,” which bowed on the list dated April 15, 1972. The single initially didn’t find wide success, and stalled out at No. 66 that year. However, “Changes” would return to the chart in 1974, following Bowie’s subsequent breakthrough with “Space Oddity” -- his first top 40 hit (it peaked at No. 15).

“Changes” ultimately peaked at No. 41 on the Feb. 1, 1975 chart. It ranks at No. 14 on our recap of Bowie’s top 20 biggest hits on the chart (see list, below).

His biggest single on the Hot 100 is his second No. 1 smash, “Let’s Dance.” The track, produced by Nile Rodgers, was the title cut of Bowie’s hugely successful 1983 album. The set peaked at No. 4 on the Billboard 200 chart, returning him to the top 10 for the first time since 1976. The effort also launched the top 20-charting hits “China Girl” and “Modern Love,” which rank at Nos. 6 and 8 on his all-time list.

Bowie’s second-biggest Hot 100 hit is his first chart-topper: “Fame.” The 1975 single was co-written with John Lennon (who also provided guitar and background vocals) and rose to No. 1 on the Hot 100 dated Sept. 20, 1975. The disco-funk track also found success on the Hot R&B/Hip-Hop Songs chart, where it reached No. 21. Its success even garnered Bowie an invitation to perform on the TV dance series Soul Train.

“Fame’s” follow-up single, “Golden Years,” is Bowie’s No. 4 biggest single. It peaked at No. 10 on the Hot 100 chart, but spent a lengthy 21 weeks on the tally. (It’s tied with “Fame” as his longest-charting single.)

Rounding out Bowie’s top five biggest Hot 100 hits is his cover of Martha and the Vandellas’ “Dancing In the Street” with Mick Jagger. The superstar collaboration was recorded in 1985 to raise funds for the Live Aid charity. It marked Bowie’s so-far final top 10 single on the Hot 100, peaking at No. 7 on the list dated Oct. 12, 1985.

David Bowie’s top 20 Billboard Hot 100 hits chart is based on actual performance on the weekly Billboard Hot 100, through the Jan. 16, 2016, ranking. Songs are ranked based on an inverse point system, with weeks at No. 1 earning the greatest value and weeks at No. 100 earning the least. Due to changes in chart methodology over the years, certain eras are weighted to account for different chart turnover rates over various periods.