SciVee - David S. Rooshttp://www.scivee.tv/taxonomy/term/8433/0
enApicomplexan Parasites, Pathogen Genome Informatics, and the Evolution of Eukaryotic Organelles: Part 3C: Designing and mining pathogen genome databases: From genes to drugs and vaccines (25:45) http://www.scivee.tv/node/10367
<p>With the emergence of genomic-scale datasets representing all of the genes in the genome, all of the proteins in a cell or tissue, and all of the interactions and signals in an organism, biologists are increasingly faced with the challenge of how to store, integrate, and interrogate this information. How can we effectively mine large-scale datasets to expedite biological discovery, for example in the identification of new targets for anti-parasitic drug and vaccine design?</p>
<div class="og_rss_groups"><ul class="links"><li class="first last og_links"><a href="/node/10295" class="og_links">iBioseminars</a></li>
</ul></div><p><a href="http://www.scivee.tv/node/10367">read more</a></p>Apicomplexan ParasitesDavid S. RoosdrugsenergyEukaryotic Organellesgenesglobal healthMiningpathogen genome databasesPathogen Genome InformaticsPenn Genomics InstituteUniversity of PennsylvaniavaccinesiBioseminarsFri, 13 Mar 2009 19:15:46 +0000video_collector10367 at http://www.scivee.tvApicomplexan Parasites, Pathogen Genome Informatics, and the Evolution of Eukaryotic Organelles: Part 3B: Designing and mining pathogen genome databases: From genes to drugs and vaccines (27:10)http://www.scivee.tv/node/10366
<p>With the emergence of genomic-scale datasets representing all of the genes in the genome, all of the proteins in a cell or tissue, and all of the interactions and signals in an organism, biologists are increasingly faced with the challenge of how to store, integrate, and interrogate this information. How can we effectively mine large-scale datasets to expedite biological discovery, for example in the identification of new targets for anti-parasitic drug and vaccine design?</p>
<div class="og_rss_groups"><ul class="links"><li class="first last og_links"><a href="/node/10295" class="og_links">iBioseminars</a></li>
</ul></div><p><a href="http://www.scivee.tv/node/10366">read more</a></p>Apicomplexan ParasitesDavid S. RoosdrugsenergyEukaryotic Organellesgenesglobal healthMiningpathogen genome databasesPathogen Genome InformaticsPenn Genomics InstituteUniversity of PennsylvaniavaccinesiBioseminarsFri, 13 Mar 2009 19:15:15 +0000video_collector10366 at http://www.scivee.tvApicomplexan Parasites, Pathogen Genome Informatics, and the Evolution of Eukaryotic Organelles: Part 3A: Designing and mining pathogen genome databases: From genes to drugs and vaccines (20:04)http://www.scivee.tv/node/10365
<p>With the emergence of genomic-scale datasets representing all of the genes in the genome, all of the proteins in a cell or tissue, and all of the interactions and signals in an organism, biologists are increasingly faced with the challenge of how to store, integrate, and interrogate this information. How can we effectively mine large-scale datasets to expedite biological discovery, for example in the identification of new targets for anti-parasitic drug and vaccine design?</p>
<div class="og_rss_groups"><ul class="links"><li class="first last og_links"><a href="/node/10295" class="og_links">iBioseminars</a></li>
</ul></div><p><a href="http://www.scivee.tv/node/10365">read more</a></p>Apicomplexan ParasitesDavid S. RoosdrugsenergyEukaryoticgenesglobal healthMiningpathogen genome databasesPathogen Genome InformaticsPenn Genomics InstituteUniversity of PennsylvaniavaccinesiBioseminarsFri, 13 Mar 2009 19:14:39 +0000video_collector10365 at http://www.scivee.tvApicomplexan Parasites, Pathogen Genome Informatics, and the Evolution of Eukaryotic Organelles: Part 2: The apicomplexan plastid: Something old, something new, something borrowed, something green (37:11)http://www.scivee.tv/node/10364
<p>Antibiotics are effective because they kill bacteria without harming humans and other eukaryotes (organisms with cells that contain nuclei). So why are the eukaryotic parasites responsible for malaria and toxoplasmosis killed by drugs like clindamycin?</p>
<div class="og_rss_groups"><ul class="links"><li class="first last og_links"><a href="/node/10295" class="og_links">iBioseminars</a></li>
</ul></div><p><a href="http://www.scivee.tv/node/10364">read more</a></p>Apicomplexan Parasitesapicomplexan plastidDavid S. RoosenergyEukaryotic Organellesglobal healthgreenPathogen Genome InformaticsPenn Genomics InstituteUniversity of PennsylvaniaiBioseminarsFri, 13 Mar 2009 19:14:25 +0000video_collector10364 at http://www.scivee.tvApicomplexan Parasites, Pathogen Genome Informatics, and the Evolution of Eukaryotic Organelles by David S. Roos, May 2008 - Part 1: How to build a parasitehttp://www.scivee.tv/node/8416
<p>There are more than 5000 species of single-celled eukaryotes in the biological phylum known as the Apicomplexa, including the parasites responsible for malaria, neurological birth defects, and opportunistic infections associated with HIV/AIDS. These ancient protozoa provide a unique window into the evolution of subcellular organelles that have long fascinated cell biologists. Familiar features help to elucidate the origins, functions and design parameters for the secretory pathway, endosymbiotic organelles, the cytoskeleton, and cell cycle control.</p>
<div class="og_rss_groups"><ul class="links"><li class="first last og_links"><a href="/node/10295" class="og_links">iBioseminars</a></li>
</ul></div><p><a href="http://www.scivee.tv/node/8416">read more</a></p>ApicomplexaApicomplexan Parasitesapicomplexan plastidbiological phylumDavid S. RoosenergyeukaryotesEukaryotic Organellesevolutionary diversityglobal healthgreenHIV/AIDSmalarianeurological birth defectsPathogen Genome InformaticsPenn Genomics Instituteprotozoasingle-celledsubcellular organellesUniversity of PennsylvaniaiBioseminarsWed, 19 Nov 2008 04:42:16 +0000video_collector8416 at http://www.scivee.tv