This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on high throughput flow cytometry (HT flow) screening carried out in December 2014.Mobile Technology In The Lab Trends 2015HTStec Limited

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on the use of mobile technology to monitor and control of lab instruments and automated systems carried out in April 2015.Epigenetic Proteins & Reagents Trends 2015HTStec Limited

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on cell-based label-free (LF) detection carried out in July and August 2014. The study also examined in detail the current market landscape, application areas and interest in purchasing new products/systems.HTS Metrics & Future Direction Trends 2014HTStec

This market report summarizes the results of HTStec’s global web-based benchmarking survey on high throughput screening (HTS) metrics and future directions carried out in July 2014. The survey was initiated by HTStec as part of its tracking of life science marketplaces and to update our previous report (April 2012). It followed an approach from Pharma to benchmark recent HTS metrics.Label-Free Binding Analysis Trends 2014HTStec

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on label-free (LF) binding analysis carried out in July 2014. The study was initiated by HTStec as part of its regular (every 2 years) tracking of this life science marketplace. The questionnaire was compiled to address the needs and interests of the LF binding analysis vendor community.Epigenetic Modification Screening Trends 2014HTStec

Multi-channel pipettors are essential tools in most life science laboratories today. Yet the impact of undertaking quality control (QC) measures on improving data quality, enhancing productivity/efficiency and reducing experimental failures has only relatively recently been recognized. Understanding how lab users approach the issue of pipettor QC is important as the industry struggles to adopt standards for automated pipetting.

Too often, image analysis and data/image mining projects remain stuck inmicroenvironments because they are limited by vendorspecificsolutions that neither scale nor interact with material from other departments or institutions. Successful rollout of digital histopathology therefore requires more than a whole slide scanner. At Brussels FreeUniversity (VUB), we wanted to provide a core digital pathology infrastructure that can support a range of different use cases.Workshop report: Bioinformatics meets digital pathologyVrije Universiteit Brussel (Belgium), UMC Radboud (Netherlands), HistoGeneX (Belgium), Rigshospitalet Copenhagen (Denmark), New York College of Podiatric Medicine (USA), Harvard Medical School & Massa

Pathologists are the guardians of large quantities of high-resolutionimaging material, that is barely noticed by bioinformatics today. Yet this (annotated) material can be of huge contributing value to any research project, as pathology preserves topological tissue features, and can help explain difficult phenomena such as tumor heterogeneity. The goal is then to bridge research methods and materials from the bioinformatics community with the (digital) pathology community.A Novel Cell-Free DNA Extraction System for Cancer DiagnosticsVela Diagnostics Pte. Ltd., Singapore

We developed a magnetic bead-based cfDNA extraction kit and integrated it into the automated qPCR- and NGS-based IVD workflows. In this study we are compering this magnetic beads-based cfDNA extraction system with a column-based method.Microfluidic extrusion of cell-laden hydrogel fibers for 3D-BioprintingCLNS - iit@Sapienza - Viale Regina Elena 291 - 00161 - Roma

An overview on how the incorporation of microfluidic platforms in 3D-bioprinters can open new routes in the creation of heterogeneous, tissue-specific bio-constructs and in the high-throughput screening of bioinks compositions for regenerative medicine and in vitro tissue modeling.CRISPR-Cas9 genome editing utilizing chemically synthesized RNAGE Healthcare Dharmacon, Inc.

Our previous study of spices was designed to evaluate the metal content in the spices for evidence of contamination by heavy metals or for adulteration and counterfeiting by notable concentrations of wear or additive metals. This study targeted the same spice samples to quantify the characteristic primary and secondary market compounds for each spice group.The Chemical Synthesis of Long and Highly Modified RNA using 2'-ACE ChemistryGE Healthcare Dharmacon, Inc.

Dharmacon has previously developed a novel RNA synthesis chemistry making RNA synthesis as reliable, accessible and of comparable quality as routinely observed in DNA synthesis.

Use of static and dynamic light scattering to characterize the stability of lysozyme in the presence and absence of arginine. SLS is used to assess aggregation temperature, while DLS is used to measure the various particle sizes present in the two formulations at different temperatures, and measurements of zeta potential are used to assess the effect of arginine on the charge state of the protein.Using DSC to Characterize Thermotropic Phase Transitions in Lipid Bilayer MembranesMalvern Instruments Limited

Strains of the yeast Saccharomyces cerevisiea serve critical roles in the production of many different products including food staples, medicines, and biofuels. The ability to obtain the desired product reliably and repeatedly requires careful monitoring of not only the input materials, but the growth of the yeast strain during the process.Protein Storage and Stability Analysis Using the Zetasizer Nano ZSP Malvern Instruments Limited

The Malvern MicroCal VP-Capillary DSC has been used for rapid screening of buffers in preformulation development and for the optimization of storage conditions of antibodies during process development. The results correspond well with those obtained by other more time-consuming methods.