I installed CS5 on my iMac running Mavericks. Photoshop works fine, but InDesign and Illustrator keep crashing upon starting the program. InDesign specifically crashes when it "registers 224 plug-ins". Illustrator crashes almost instantly. Adobe phone tech support is not available because this is not a creative cloud subscription. Has anybody else encountered this issue?

OK, that makes it a user issue. Trashing the prefs after logging in on the regular account may be enough (see Replace Your Preferences ), but if that doesn't do it, rename the two InDesign folders in your user library (see Access hidden user library files | Mac OS 10.7 and later for how to find the folders. The two paths are listed in the previous link), then copy the folders from the guest account.

Sorry it has been a busy few days in the office - but I still would like to get this program running...

Tried replacing the entire Adobe Folder - still not the answer...

I've replaced all these folders too that are appeared after successfully launching InDesign in the Guest Account (see images)

My preferences and cache folders in my main user account have a ton of files and folders compared to my guest account. Could that be the source of the problem? I can post screen shots if you think that they may be the source?

I've been using a removable drive to transfer the files between the guest account and the admin(main) user account because I can't access the main account. Would you think that creating a new permanent account would be any different?

I created a new admin account and copies the library files without a removable drive. We may be getting closer...InDesign still crashes but it crashes when the screen shows "Starting up service registry" rather than "registering 212 plug-ins"