It's important to remember that Supplements are powerful, which is why we take them of course. But what we don't often think about is their potential interaction with prescription medications we are also taking. Based on the meds I am taking, my MD probably couldn't tell me what Supplements to avoid, unless they were obvious ones. Do your research!

Supplements can increase the effect of some medications or inhibit the effectiveness of others. They may interact in a way that is less than desirable, so it's important to tell you doctor when you are thinking of adding supplements, and if she/he isn't sure about interactions, turn to the a reliable internet source, or better yet, an Anthroposophic or CAM practitioner.

Below is a list of some common Supplements and possible interactions.

Aloe Vera

Major interaction: Digoxin (Lanoxin)

When taken by mouth, aloe latex is a type of laxative called a stimulant laxative. Stimulant laxatives can decrease potassium levels in the body. Low potassium levels can increase the risk of side effects of digoxin (Lanoxin).

Taken orally, aloe vera may also interact with blood sugar-lowering medicine used to treat Diabetes.

Bitter Orange

There have been reports of fainting, heart attack, and stroke in healthy people after taking bitter orange supplements alone or combined with caffeine. People should avoid taking bitter orange supplements if they have a heart condition or high blood pressure, or if they are taking medications (such as MAO inhibitors), caffeine, or other herbs/supplements that speed up the heart rate.

Due to lack of safety evidence, pregnant women or nursing mothers should avoid products that contain bitter orange.

Bitter orange oil used on the skin may increase the risk of sunburn, particularly in light-skinned people

Ginseng

Major Interaction: Warfarin (Coumadin)

American ginseng has been reported to decrease the effectiveness of Warfarin (Coumadin). Decreasing the effectiveness of warfarin (Coumadin) might increase the risk of clotting. Do not take American ginseng if you take warfarin (Coumadin).

American ginseng might stimulate the body. Some medications used for depression can also stimulate the body. Taking American ginseng along with these medications used for depression might cause side effects such as anxiousness, headache, restlessness, and insomnia. Some of these medications used for depression include phenelzine (Nardil), tranylcypromine (Parnate), and others.

Kava

In March 2002, the U.S. Food and Drug Administration (FDA) issued an advisory to consumers of the potential risk of severe liver injuryfrom the use of dietary supplements containing kava (also known as kava kava or Piper methysticum). Reports from health authorities in Germany, Switzerland, France, Canada, and the United Kingdom have linked kava use to at least 25 cases of liver toxicity, including hepatitis, cirrhosis, and liver failure, prompting some of these countries to remove kava from the market.

Avoid driving and operating heavy machinery while taking kava because the herb has been reported to cause drowsiness.

Licorice Root

People with heart disease or high blood pressure should be cautious about using licorice.

When taken in large amounts, licorice can affect the body’s levels of a hormone called cortisol and related steroid drugs, such as prednisone.

Pregnant women should avoid using licorice as a supplement or consuming large amounts of licorice as food, as some research suggests it could increase the risk of preterm labor.

Moderate Interaction:

Birth control pills (Contraceptive drugs)

The body makes melatonin. Birth control pills seem to increase how much melatonin the body makes. Taking melatonin along with birth control pills might cause too much melatonin to be in the body. Some birth control pills include ethinyl estradiol and levonorgestrel (Triphasil), ethinyl estradiol and norethindrone (Ortho-Novum 1/35, Ortho-Novum 7/7/7), and others.

Caffeine

Caffeine might decrease melatonin levels in the body. Taking melatonin along with caffeine might decrease the effectiveness of melatonin supplements.

Fluvoxamine (Luvox)

Taking fluvoxamine (Luvox) can increase the amount of melatonin that the body absorbs. Taking melatonin along with fluvoxamine (Luvox) might increase the effects and side effects of melatonin.

Vitamin K

Warfarin (Coumadin) interacts with VITAMIN K: Vitamin K is used by the body to help blood clot. Warfarin (Coumadin) is used to slow blood clotting. By helping the blood clot, vitamin K might decrease the effectiveness of warfarin (Coumadin). Be sure to have your blood checked regularly. The dose of your warfarin (Coumadin) might need to be changed.

Yohimbe

Yohimbe has been associated with high blood pressure, increased heart rate, headache, anxiety, dizziness, nausea, vomiting, tremors, and sleeplessness. Yohimbe can be dangerous if taken in large doses or for long periods of time.

People should not combine yohimbe with MAO inhibitors as effects may be additive. Yohimbe should be used with caution when taken with medicines for high blood pressure, tricyclic antidepressants, or phenothiazines (a group of medicines used mostly for mental health conditions such as schizophrenia).

People with kidney problems and people with psychiatric conditions should not use yohimbe.

Women who are pregnant or breastfeeding should not take yohimbe.

Zinc

FDA notified consumers and healthcare professionals to discontinue use of three Zicam Nasal Gel/Nasal Swab products sold over-the-counter as cold remedies because they are associated with the loss of sense of smell that may be long-lasting or permanent. The FDA has received more than 130 reports of loss of sense of smell associated with the use of the three Zicam products. In these reports, many people who experienced a loss of smell said the condition occurred with the first dose; others reported a loss of the sense of smell after multiple uses of the products.

Conversely, if you are taking any of the following drugs, see cautions below.

Aspirin

Aspirin DEPLETES Folic Acid, zinc, potassium, vitamin C and iron. Avoid higher doses of the following if you take Aspirin. Vitamin E,. Bromelain, Garlic, Ginger, Magnesium, Ginkgo, all which act as blood thinners and thus could cause bleeding.

Ativan

Avoid any herbs that act as a sedative, like Kava Kava, Lemon Balm, Calif. Poppy, St. John's Wort or Valerian. Exception: Melatonin.

Lisinopril

This also DEPLETES Zinc, which could lead to an increase in blood Copper levels and foster cancer angiogenesis and progression. Zinc supplements are encouraged if taking this medicine.

Lovastatin

Take Fiber supplements 1 - 2 hours away from this med to avoid reducing its absorption.

Niacin taken in large doses with this drug has been reported to cause potentially serious muscle disorders. Bu taking a low dose (500mg) actually enhances the effectiveness of the Statin drug. IT may also be beneficial to take Vitamin E with this drug to prevent the possibility of oxidative damage to LDL cholesterol.

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