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Hi, I had the same inital problem as you, except I didn't put a new video card as I was please with the Onboard card performance that even has an HDMI port. Not sure if your problem is solved already, but in my working process, I first suspected the Power Supply, and I had everything out of the case but the Mother Board. When I tried to fire it up I was always getting "No signal" on the screen, not even a blink from the BIOS. I then put everything back in place, then after the HD started spinning of and Windows booting, the screen started coming on. I felt it was like if I needed Windows to have a clean booth to replace the video drivers and switch to the InBoard card. Hoping this of any help.

Actually it boots, just that you don't see it. Try using another monitor - even a tv will do: disconnect the present monitor, connect the new one and reboot. If you get an image then the monitor is dead, replace it. If you don't then the onboard video card id dead, get a new one and try again. If even now it.s dead then you need a new motherboard.

I had exactly the same problem on my friends Dell GX280. It will only let you use the onboard card or the new radeon card not both together. In the end we had to buy a Radeon card that was made specifically for two monitors and disable the onboard card on BIOS. It would not let us use the two seperate cards in unison.

You were not very clear with your question. If you mean you have disabled your onboard video, then installed the new video card and get nothing then the card is not compatible with your system OR you got a bad card.
If you mean you simply installed the card, turn on your computer and get nothing until you move your monitor plug back to the original port (without turning off the computer) then you must disable your onboard video by going into your BIOS settings. Follow the instructions that came with your video card or your computer to do that. Usually you get in by pressing delete or F2 while the computer boots.

Here are a couple steps you can do to verify something didn't come on correctly. - Verify the monitor cable is connected tightly to the monitor and PC. - Verify the power cable is plugged in.

If both of these check out is there a little LED light on your monitor that is on?If not swap it out with another monitor and see if a different one works. If so we have a bad monitor.If both do not work you may have a video card issue. Most EMachines come with a onboard video card which is bad news. If you have a onboard video card you will have to verify the warrantly though Emachine and get it fixed. Good luck and I hope things go well.

Do a reset: Turn the computer and monitor off. Unplug the monitor video cable from the computer and unplug the monitor power cord from the wall outlet. Let it sit for 5 or 10 minutes. Plug everything back in, turn on the monitor, then start the computer. Sometimes that will work.
If you still have the same problem, try to borrow a known to be good monitor from somebody. If it works, then you know your monitor is bad.
It's also possible that your video circuitry is bad. If the monitor plugs straight into the motherboard (onboard video), then you'll need to purchase a video card and install it. Disable the onboard video first.