Long-term use of penicillamine can cause zinc deficiency.
3
However, zinc can impair penicillamine absorption, so do not take zinc supplements during the 2 hours before or after your penicillamine dose.
4

Penicillamine attaches to the mineral iron, which impairs the absorption of both substances.
5,6
The solution: If you need iron supplements, do not take them during the 2 hours before or after your penicillamine dose.

Revision Information

This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.