Material
Uses: Used as a rheology control, reinforcement and free flow agent in Silicone
Rubber, Coatings, Adhesives, and Pharmaceuticals etc.

Section
III – Hazards Identification

Main Hazards:
Dry powdered materials can build static electrical charges when subjected to
friction.Proper precautions when using
CAB-O-SIL (registered trade name) fumed silica in the presence of flammable or
explosive gasses and liquids should be taken to prevent accidents.

Potential Health effects:Eye:
May cause irritation at high dust levels

Skin:
May cause drying of skin

Ingestion:
None expected

Inhalation:
Temporary discomfort due to inhalation of dust

Chronic:
Not listed as carcinogen by IARC, NTP, Z list or OSHA

Teratology:
None identified

Reproductive
Info: None identified

Target
Organs: Lung

Section
IV – First Aid Measures

Inhalation:
Not hazardous.In case of discomfort,
remove exposed individual to fresh air

Ingestion:
Not hazardous.No treatment required

Eyes:
Immediately flush lightly with plenty of water for 15 minutes. Get medical
attention

Spill Cleanup
Measures: Spills may be collected, preferably by vacuum, and placed in suitable
container for disposal.

Environmental
Precautions: Fumed silica is a not hazardous waste.Dispose of in landfill in accordance with international,
national, U.S. federal and local laws and regulations.

Section
VII – Handling and Storage

Handling Precautions: Ventilated work area if necessary.
Take precautionary measures against possible build-up of electrostatic charge.
Assess manual handling of bagged product; take suitable precautions.

Storage:
Product should be stored dry and away from volatile chemicals.

Engineering
Controls: Use general or local exhaust ventilation to meet exposure limit
requirements

Other
Protective Measures: Wash exposed skin and clothing frequently

Section
IX – Physical and Chemical Properties

Physical
State: Solid powder

Color: White

Odor: None

Odor
Threshold: Not applicable

ph: 4.0
(approximately 4% silica in water)

Boiling
Point: 2230 degree Celsius

Evaporation
Rate: Not applicable

Melting/Freezing
Point: 1700 degree Celsius or 3092 degree Fahrenheit

% Volatile by
Volume: Not applicable

Solubility in
Water: Insoluble in water

Density:2.2 g/cubic centimeter @ 25 degree Celsius

Vapor
Pressure: Not applicable

Water/ Oil
Distribution: Not applicable

Viscosity:
Not applicable

Pour Point:
Not applicable

Section
X – Stability and reactivity

Chemical
Stability: Stable

Conditions to
Avoid: None

Incompatible
Materials: Not applicable

Reactivity:
Stable

Hazardous
Decomposition: None

Hazardous
Polymerization: None

Section
XI – Toxicological Information

Routes of
exposure: Ingestion, Inhalation, Eye and Skin

Acute
Inhalation Effect: None known other than possible temporary discomfort

Acute
Ingestion Effect: None expected

Acute Eye
Effect: Irritation at high dust levels

Acute Skin
Effect: May cause drying of skin

Chronic
Inhalation Effect: There is no human data available that suggests that
occupational exposures to synthetic fumed silica will cause adverse chronic
health effects.Long-term inhalation
animal studies involving a variety of insoluble solid particles have resulted
in chronic inflammation, lung fibrosis and lung tumors in rats.Tumors were not observed in similar studies
using other animal species (i.e., mouse and hamster).Most inhalation toxicologists feel the tumor response is unique to
rats and not relevant to human exposure.Synthetic fumed silica was not used in these tests.The researchers who conducted the above
studies felt the adverse reactions in the rat were due to high exposure levels
of insoluble dusts overwhelming the lung clearance mechanisms (lung overload phenomenon)
and is not the result of specific chemical effect of the particulate
tested.This effect is not expected to
occur from occupational exposure to synthetic amorphous silica.

Section
XI – Toxicological Information, continued

Chronic Ingestion effect: None expected

Chronic eye effect: None expected

Chronic skin effect: None expected

Sensitization to Material: None expected

Medical Conditions Aggravated: Dermatitis

Synergistic Materials: None expected

Mutagenicity: In-vitro and in-vivo tests negative for
mutagenicity

Reproductive Toxicity: None known

Teratogenicity: None known

Carcinogenicity: Not listed as a carcinogen By IARC, NTP,
Z list or OSHA

Legal Classification: Not
hazardous waste under U.S. RCRA (Resource Conservation and Recovery Act)
Regulations.Not a
restricted/non-hazardous waste under Canadian Workplace Hazardous Materials
Information Systems (WHMIS) regulations.Fumed silica is not a special waste under U.K. Special Waste Regulations
1996.Dispose of in accordance with
local regulations.These regulations
implement EC directive 91/689 and decision 94/904.

U.S. Clean Air Act, 1990: (CAA Section 112, 40
CFR82):CAB-O-SIL (registered trade
name) fumed Silica does not contain and is not manufactured with Class I or
Class II ozone depleting chemicals, as defined in the Clean Air Act of 1990.

SARA Section
313 (40 CFR 372):Does not contain any
of the substance identified under Section

313 as toxic.

U.S. CONEG Legislation: Not determined.

U. S. FDA Regulations: The use of CAB-O-SIL (registered
trade name) has been approved by the United States Food and Drug Administration
(FDA) for many food applications as both direct food additive at levels up to 2
% by weight and as a substance allowed in the manufacture of materials that
come in direct contact with food in various producing, manufacturing, packing,
preparing, transporting and holding operations. Pertinent sections can be found
in Title 21 Code of Federal Regulations, Part 172 Food Additives Permitted for
Direct Addition to Food for Human Consumption.

Section XVI – Other
Information

Pharmaceutical Information:
CAB-O-SIL meets all of the requirements for colloidal silicon dioxide as
describe in the U.S. Pharmacopoeia National Formulary.It also meets the requirements as described
in the European Pharmacopoeia and the Deutsches Arzneibuch (DAB 1996) and the
Japanese Pharmacopoeia.It appears in
the Handbook of Pharmaceutical Excipients under the monograph, colloidal
silicon dioxide.

Last Revision: May 6, 2015.

Disclaimer: The information set
forth is based on information that is believed to be accurate.No warranty, expressed or implied, is intended.The information is provided solely for your
information and consideration and assumes no legal responsibility for use or
reliance thereon.