The improvement in symptoms was similar regardless of the weight maintenance program followed; either a dietary intervention, a program of knee exercises, or no formal intervention (controls). The results suggest that weight loss is the key component to knee OA pain relief, according to Henning Bliddal, MD, DMSc, of Copenhagen University Hospital, and colleagues.

The finding, which comes from an assessment of data from CAROT (Cartilage in Obese Knee Osteoarthritis Patients Trial), “confirms the feasibility of long-term weight loss maintenance in sedentary individuals, in this case patients with mobility limitations due to knee OA,” the authors wrote.

The investigators found that those doing exercises for their knee OA with no weight loss did worse than those who lost weight leading them to conclude that diet is mandatory for the weight loss to minimize knee pain from OA.

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