NASA/Dimitri Gerondidakis(LOS ANGELES) -- Space shuttle Endeavour embarked on its final mission Friday, traveling through the streets of South Los Angeles to reach its new home at the California Science Center.

The 165,000-pound shuttle will be on the road for two days as it makes the 12-mile trip from Los Angeles International Airport, where it had been since late September. Once it arrives at the CSC, it will be put on permanent display.

Endeavour was built after the loss of the shuttle Challenger in 1986 and became NASA’s fifth space shuttle orbiter. It made its first flight in 1992 and in its 25 missions, it orbited the Earth more than 4,600 times and spent 299 days in space.