Traditionally, family psychodynamics, family bonding etc. have been implicated in pathogenesis of infantile colic. Use of modern molecular probes has shown that there is significant dysbiosis in these patients.

de Weerth and colleagues compared the microbial DNA of more than 200 samples from 12 infants with intestinal colic and 12 age-matched control infants. These investigators found that bacterial diversity increased only the healthy control babies and not in those with colic.

Samples were also less stable during the first few weeks in those with colic. Differences in bacterial patterns could be seen as early as week 1 or 2 of life.

The number of Proteobacteria is was more than 2 times higher in babies with colic as compared with control infants. The number of bifidobacteria and lactobacilli were significantly reduced in colic group.

Research also indicates that fewer the Actinobacteria Bifidobacterium and Firmicute Lactobacilli bacteria, the greater the crying and fussiness in babies. Such changes are significant because the imbalance is being created as a result of bacteria not normally abundant in the gut.

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Disclaimer Autism

Postings are for general information and not intended for advice or use for self-diagnosis or treatment. I am a gastroenterologist and nutritionist, not your physician or autism specialist. Always read everything on internet with a grain of salt and consult your physician.