Application Information: Ga15/16 antibody

Western blotting (0.5-4 μg/ml) and in Immunohistochemistry (5-20 μg/ml). However, the optimal conditions should be determined individually. The antibody detects G

Form Supplied

Liquid

Concentration

0.5
mg/ml
(Please refer to the vial label for the specific concentration)

Purification

Affinity purified

Specifications: Ga15/16 antibody

Full Name

guanine nucleotide binding protein (G protein), alpha 15 (Gq class)

Product Description

Rabbit polyclonal antibody to Ga15/16

Background

Galpha 16 is the only heterotrimeric G protein with a restricted expression pattern in hematopoietic cells. Differentiation of promyelocytic cells leads to decreased expression of Galpha 16. The G protein is known to couple a large number of G protein-coupled receptors to PLC-beta and can lead to production of the secondary messengers diacylglycerol and inositol phosphates. Targeted deletion of Galpha 15, a mouse orthologue of human Galpha 16, causes reduced C5alpha receptor signaling. Galpha 16 serves as a marker, in addition to CD34, for hematopoietic progenitor cells.

Synonyms

G alpha binding protein

Specificity

This antibody is specific for Ga15/16.

Host

Rabbit

Clonality

Polyclonal

Target

Ga15/16

Isotype

IgG

Species Reactivity

Human, Mouse, Rat

Storage Conditions: Ga15/16 antibody

Storage Buffer

PBS (pH 7.2) containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Storage Instruction

The antibody solution should be gently mixed before use. Stored at -20 °C for future use.

Notes

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.