We all vary in how often we become happy, sad or angry, and also in how strongly these emotions are expressed. This variability is a part of our personality and can be seen as a positive aspect that increases diversity in ...

Healthy people given the serotonin-enhancing antidepressant citalopram were willing to pay almost twice as much to prevent harm to themselves or others than those given placebo drugs in a moral decision-making experiment ...

Alcohol use disorder as defined by a new diagnostic classification was widespread and often untreated in the United States, with a lifetime prevalence of 29.1 percent but only 19.8 percent of adults were ever treated, according ...

Scientists at Mayo Clinic, Jacksonville, Florida created a novel mouse that exhibits the symptoms and neurodegeneration associated with the most common genetic forms of frontotemporal dementia (FTD) and amyotrophic lateral ...

Researchers at Mayo Clinic in Florida have developed a mouse model that exhibits the neuropathological and behavioral features associated with the most common genetic form of amyotrophic lateral sclerosis (ALS or Lou Gehrig's ...

With no lab tests to guide the clinician, psychiatric diagnostics is challenging and controversial. Antisocial personality disorder is defined as "a pervasive pattern of disregard for, and violation of, the rights of others ...

Every day we make decisions based on predicting what someone else will do - from deciding whether the driver approaching an intersection will stop for the red light to determining whether a particular negotiation strategy ...

Psychopathic violent offenders have abnormalities in the parts of the brain related to learning from punishment, according to an MRI study led by Sheilagh Hodgins and Nigel Blackwood. "One in five violent offenders is a psychopath. ...

Some children are more sensitive to their environments, for better and for worse. Now Duke University researchers have identified a gene variant that may serve as a marker for these children, who are among society's most ...

A study by University of Iowa researchers confirms that pathological gambling runs in families and shows that first-degree relatives of pathological gamblers are eight times more likely to develop this problem in their lifetime ...

An unprecedented research conducted by a group of neuroscientists has demonstrated for the first time that it is possible to train brain patterns associated with empathic feelings – more specifically, tenderness. The research ...

Adolescents with antisocial personality disorder inflict serious physical and psychological harm on both themselves and others. However, little is yet known about the underlying neural processes. Researchers at the University ...

Mood and emotion are extremely complex aspects of behavior that are known to involve the neurotransmitters serotonin and norepinephrine. Both neurotransmitters are broken down by an enzyme called monoamine oxidase A (MAO-A), ...

Antisocial personality disorder (ASPD) is described by the American Psychiatric Association's Diagnostic and Statistical Manual, fourth edition (DSM-IV-TR), as an Axis II personality disorder characterized by "...a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood."

The World Health Organization's International Statistical Classification of Diseases and Related Health Problems', tenth edition (ICD-10), defines a conceptually similar disorder to antisocial personality disorder called (F60.2) Dissocial personality disorder.

The American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders incorporated various concepts of psychopathy/sociopathy/antisocial personality in early versions but, starting with the DSM-III in 1980, used instead the term Antisocial Personality Disorder and focused on earlier behavior instead of using personality judgements. The World Health Organization's ICD incorporates a similar diagnosis of Dissocial Personality Disorder. Both the DSM and the ICD state that psychopathy (or sociopathy) are synonyms of their diagnosis.

Psychopathy and sociopathy are terms related to ASPD. ASPD replaced psychopathy as a diagnosis in the DSM but the terms are not identical. Psychopathy is now (like sociopathy) usually seen as a subset of ASPD.

Latest Spotlight News

Many hormones and neurotransmitters work by binding to receptors on a cell's exterior surface. This activates receptors causing them to twist, turn and spark chemical reactions inside cells. NIH scientists used atomic level ...

If you've had a good night's sleep, you are mentally more alert and your memory works more reliably. During sleep, a part of our forebrain called the prefrontal cortex remains active. It ensures that memories and learned ...

A team of researchers with affiliations to a number of research centers in the U.S. has found that the protein p53 serves as a controlling mechanism for apoptotic (naturally dying) cells through the immunoglobulin Death Domain ...

Follicular helper Tcells (TFH cells), a rare type of immune cell that is essential for inducing a strong and lasting antibody response to viruses and other microbes, have garnered intense interest in recent years but the ...

A study by researchers at the National Institute of Allergy and Infectious Diseases and Duke University helps explain why the candidate vaccine used in the HVTN 505 clinical trial was not protective against HIV infection ...

New research from Harvard T.H. Chan School of Public Health describes a molecular mechanism that helps explain how obesity-related inflammation can lead to type 2 diabetes. The findings describe a surprising connection between ...

In a study conducted at UCLA, five men who had been completely paralyzed were able to move their legs in a rhythmic motion thanks to a new, noninvasive procedure that stimulates the spinal cord. It is believed to be the first ...

In the last two decades, prosthetic limb technology has grown by leaps and bounds. Today, the most advanced prostheses incorporate microprocessors that work with onboard gyroscopes, accelerometers, and hydraulics to enable ...