Cuoco’s co-stars including Jim Parsons, Mayim Bialik, Melissa Rauch, Kunal Nayyar and Simon Helberg all joined in with the dance, set to the Backstreet Boys’ Larger Than Life, while the studio audience clapped along.

Johnny Galecki, who plays Leonard Hofstadter, sat out after suffering an ankle injury.

The cast and crew spent months rehearsing the dance, according to Cuoco, who said “it was worth it”.

It is not the first time the cast of The Big Bang Theory has taken part in on-set flash mobs, having previously danced along to hits including Bruno Mars’ Uptown Funk and Call Me Maybe by Carly Rae Jepsen.