Intraperitoneal adhesions after openor laparoscopic abdominal procedure: An experimental study in the rat

2nd International Conference on Surgery and Anesthesia

Background:
Adhesion formation is common after abdominal surgery. The incidence and severity of adhesionformation
following open or laparoscopic surgery remain controversial. The role of CO
2
pneumoperitoneum is also widely discussed.
This study aimed to compare adhesion formation following peritoneal injury by electrocoagulation performed through open or
laparoscopic procedures in a rat model.
Materials and Methods:
Sixty male rats were randomized to undergo a 1.5 cm peritoneal injury with unipolarcautery under
general anesthesia: open surgery (Group A, n=20), laparoscopic surgery with CO
2
pneumoperitoneum (Group B, n=20), and
laparoscopic surgery with air pneumoperitoneum (Group C, n=20). Duration of the procedures was fixed at 90 minutes in all
groups, and pneumoperitoneum pressure was kept at 10 mm Hg. Ten days later, the animals underwent a secondary laparotomy
to score peritoneal adhesions using qualitative and quantitative parameters.
Results:
Forty-five rats developed at least one adhesion: 95% in Group A, 83% in Group B, and 55% in Group C (P