http://jurnal.unissula.ac.id/index.php/sainsmedika/issue/feedSains Medika: Jurnal Kedokteran dan Kesehatan2018-11-11T18:13:46+00:00Prof. Dr. dr. Taufiqurrachman Nasihun, M.Kes., Sp.And.sainsmedika@unissula.ac.idOpen Journal Systems<div style="text-align: justify;"><p>Sains Medika <strong>: Jurnal Kedokteran dan Kesehatan</strong> is a peer-reviewed journal published by UNISSULA Press.</p><p><strong>Sains Medika: Jurnal Kedokteran dan Kesehatan </strong>consist manuscripts which correlate with medical and health and is not published in any other publisher(s).</p><p>The editorial staffs receive manuscripts from <strong>medical doctors, health professionals and other professionals related to medicine and health from all over Indonesia and overseas.</strong> <strong>Sains Medika: Jurnal Kedokteran dan Kesehatan</strong> does not levy any submission fee or page charges to any author. We also provide other author benefits, such as free PDFs.</p><p>Manuscripts are written in good mannered English. Manuscripts must be typed on A4 paper (210 x 297mm), font Calisto MT Size 10, 1,5 spacing using Microsoft Word. Full manuscript must be submitted through <a href="/index.php/sainsmedika/about/submissions#onlineSubmissions" target="_blank">Online Submission</a> in O<strong>pen Journal System (OJS)</strong> and email at: <strong>sainsmedika@unissula.ac.id</strong></p></div>http://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/2918Corneal Curvature Measurements Utilizing a New Swept-source Optical Coherence Tomography Tomey OA-2000® and Comparison With IOL Master® 500 in Pterygium Patients2018-11-11T18:13:46+00:00Mohd Radzi Hilmimohdradzihilmi@iium.edu.myKhairidzan Mohd Kamalkhairidzan@gmail.comMohd Zulfaezal Che Azeminzulfaezal@iium.edu.myMohd Hafidz Ithninmohdhafidz_ithnin@iium.edu.myMd Muziman Syah Md Mustafasyah@iium.edu.myFirdaus Yusof@Aliasyfirdaus@iium.edu.myNorsham Ahmadansham@iium.edu.my<div class="WordSection1"><p><strong>Introduction:</strong> Corneal curvature (CC) is an important anterior segment parameter. This study compared CC measurements conducted with two optical devices in pterygium eyes. <strong>Methods:</strong> Sixty pterygium eyes of 30 patients were enrolled in this study. CC was measured three times with the optical biometer and topography-keratometer Tomey OA-2000 (Tomey Corporation, Nagoya, Japan), then with partial optical coherence interferometry (PCI) IOL Master 500 (Carl Zeiss Meditec, Dublin, CA) and data were statistically analysed. <strong>Results:</strong> The measurements revealed in a mean CC of 43.86 ± 1.57 D with Tomey OA-2000 and 43.84 ± 1.55 D with IOL Master. Distribution of data is normal, and no significance difference in CC values was detected (<em>P</em> = 0.952) between the two devices. Correlation between CC measurements was highly significant (r = 0. 99; <em>P</em> &lt; 0.0001). The mean difference of CC values between devices was 0.017 D and 95% limit of agreement was -0.088 to 0.12. Duration taken for measurements with the standard biometer IOL Master was longer (55.17 ± 2.24 seconds) than with Tomey OA-2000 (39.88 ± 2.38 seconds) in automatic mode. Duration of manual measurement with Tomey OA-2000 in manual mode was shorter (28.57 ± 2.71 seconds). <strong>Conclusion:</strong> In pterygium eyes, CC measured with Tomey OA-2000 and IOL Master showed similar values, and high correlation was observed between these two devices. This shows that both devices can be used interchangeably. Tomey OA-2000 is better in terms of faster to operate and has its own topography systems.<strong></strong><strong></strong><br /><strong></strong></p></div>2018-11-11T18:12:53+00:00Copyright (c) 2018 Sains Medikahttp://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/2468HIGH DOSE VITAMIN C ADMINISTRATION EFFECT IN LEYDIG CELLS, SERTOLI CELLS NUMBER, AND SPERM QUALITY ON MALE WISTAR RATS2018-11-11T18:13:46+00:00Ratna Dwi Juniatiningrumnanasnowwhite20@gmail.com<p><strong>Introduction:</strong> Most infertile male are associated with poor spermatogenesis due to oxidative stress, and can be prevented with vitamin C. However, excessive amount of high dose of vitamin C can hindered and lower the sperm quality. <strong>Objective: </strong>To prove that high dose vitamin C is capable to decrease the number of leydig cells, sertoli cells, and sperm quality on male wistar rats.</p><p><strong>Methods:</strong> This research was using experimental method with <em>Post</em> <em>Test Only Controlled Group Design.</em> Of 24 male Wistar rats, divided randomly to 4 groups. Normal groups (Nor -G), only given 2 ml/day distilled water; vitamin C group (VC18-G, VC36-G, and VC72-G) given 18 mg/day, 36 mg/day and 72 mg/day vitamin C respectively, dissolved in 2 ml of distilled water. Sperm, the number of Leydig cells and Sertoli cells were taken from the epididymis and left right testicle on day 21. Sperm analysis using WHO standard, while the number of Leydig cells and Sertoli cells with HE staining.</p><p><strong>Result</strong>s<strong>:</strong> Mann Whitney analysis indicated that the number of sperm in VC36-G and VC72-G are lower compared to that of Nor-G and VC18-G groups, p &lt;0.05. Post-Hoc LSD analysis showed that the lowest number of Leydig and Sertoli Cell, and the weakest sperm motility and morphology in VC36-G and VC72-G groups, compared to that of Nor-G and VC18-G groups, p &lt;0.05.</p><p><strong>Conclusion:</strong> Vitamin C 36 and 72 mg/day were capable of reducing Leydig and Sertoli cells number, and worsen sperm quality, characterized by decreased in sperm concentration, motility and morphology in Wistar male- rats.</p>2018-11-11T18:12:54+00:00Copyright (c) 2018 Sains Medikahttp://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/2264RELATIONSHIP BETWEEN FAMILY HISTORY, BLOODY STOOL, PALPABLE MASS, ANEMIA, AND MSCT ABDOMEN AND KOLON CARSINOMA Cross-Sectional Study at Dr.Kariadi General Hospital in 20162018-11-11T18:13:46+00:00Ricat Hinaywan Malikricat.malik@gmail.comWinarto Winartoricat.malik@gmail.comSelamat Budijitnoricat.malik@gmail.comUdadi Sadhanaricat.malik@gmail.comYan Wisnu Prajokoricat.malik@gmail.com<p><strong>Background:</strong> Colon cancer, a colorectal cancer, is the third most common epithelial malignancy in the world. Family history, bloody stool, palpable mass, anemia, and abdominal MSCT are symptoms and signs of colon carcinoma. <strong>Objective:</strong> To determine the relationship between the 5 variables and the incidence of colon carcinoma at Dr. Kariadi Hospital, Semarang in 2016.</p><p><strong>Methods:</strong> a Cross-sectional observational analytical study using medical record (RM) and complementary primary data. The inclusion criteria were the complete medical record, and clinical diagnosis of suspected colon carcinoma. Data obtained from the department of Anatomy Pathology/PA (11,794 PA results) were traced to the medical record section (46 patients with suspected colon carcinoma). The incomplete data were confirmed by: contacting the patient/family, obtaining the archive in the laboratory and radiology resulting in 27 patients meeting the inclusion criteria. Analysis was done using chi-square test, Spearman-Kendall bivariate correlation, and logistic regression.</p><p><strong>Results:</strong> Abdominal MSCT was moderately associated with colon carcinoma (p = 0.003; r = 0.488), while family history, bloody stool, palpable mass, and anemia were not associated with colon cancer. Analysis between predictors of outcome: Bloody stool was moderately associated with anemia (p = 0.006; r = 0.411), and anemia was weakly associated MSCT (p = 0.035; r = 0.351). Abdominal MSCT was the predictive factor for colon carcinoma (p = 0.021).</p><p><strong>Conclusion:</strong> Abdominal MSCT was found to be associated with the incidence of colon carcinoma. Bloody stool was associated with anemia, and anemia was associated with abdominal MSCT. MSCT was the predictive factor for colon cancer.</p><p><strong><br /></strong></p>2018-11-11T18:12:53+00:00Copyright (c) 2018 Sains Medikahttp://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/1060CORRELATIONS BETWEEN ATTITUDES AND RATIONAL USE OF ANTACID IN SELF MEDICATION (Study on Health Students of Universitas Muhammadiyyah Malang)2018-11-11T18:13:46+00:00Witri Rochaeni Husniarwitrihusniar28@gmail.comLiza Pristiantyi.ratna80@gmail.comIka Ratna Hidayatii.ratna80@gmail.com<p><strong>Intoduction: </strong>Self-medication is the selection and use of modern drugs, herbs, and traditional medicines by individuals to overcome diseases or symptoms of disease. One mild disease that can be treated with self-medication is gastritis. The over-the-counter medication which is frequently used in treating gastritis in self- medication is antacid.</p><p><strong>Objective:</strong> To determine the correlation between attitudes and antacid rational use in self-medication among health students at the Universitas Muhammadiyah Malang.</p><p><strong>Methods:</strong> observational analytic method using questionnaire was used for this study. The sample consist of 97 people who met inclusion criteria. Sampling was done by <em>purposive sampling method</em>, then the data were analyzed using <em>Rank Spearman </em>analysis using SPSS. This research was conducted at the campus II, Universitas Muhammadiyah Malang.</p><p><strong>Results:</strong> The results showed that 97 students of health had negative attitudes of 42% (41) and positive attitude of 58 % (56). The rational use of antacid drugs as much as 60% (58), the irrational use of drugs is 40% (39). Results of analysis using <em>Spearman rank </em>correlation test values were rcount 0.680 &gt; rtable 0.202.</p><p><strong>Conclusion:</strong> The results of this study indicated that there is a significant correlation between a positive attitude to the antacid rational use in self-medication on Health Students of Universitas Muhammadiyah Malang</p>2018-11-11T18:12:53+00:00Copyright (c) 2018 Ika Ratna Hidayatihttp://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/1594OBESITY AS A RISK FACTOR FOR SURGICAL SITE INFECTION AFTER TRANSPERITONEAL CESAREAN SECTION2018-11-11T18:13:46+00:00Rahayu Rahayu Rahayurahayu.md5059@gmail.comSurgical site infection (SSI) is one of the main complications that can increase morbidity and mortality in obese women after cesarean section. Surgical site infection can be caused by endogenous or exogenous factors. This was a case of a woman, G4P3A0, 32 years, after trans-peritoneal cesarean section for indications of breech presentation; primary uterine inertia; premature rupture + 22 hours with BMI = 30.80 kg/m2. This case report discusses how obesity causes surgical site infection and its management.2018-11-11T18:12:54+00:00Copyright (c) 2018 Rahayu Rahayu Rahayu