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This thesis aims to propose a policy-relevant science, technology and innovation indicator for developing countries. I firstly develop a model to examine the determination of innovativeness for a sample of 38 developing countries, based on endogenous growth theory and innovation systems literature. From econometric estimation, I find that R&D inputs, technology imports, and international connectedness are influential determinants of innovativeness in these countries. From this finding, I develop the Predicted Innovativeness Index for Developing Countries (INNÔDEX), a composite indicator that ranks countries according to their innovative capabilities.