This ethnobotanical research was conducted in the area of Slavonski Brod and several surrounding villages
(Oriovac, Slavonski Kobaš, Brodski Stupnik, Staro Topolje) and in the area of Gunja, the research included 12 respondents
age range from 45 to 85 years. Selection criterion was that their knowledge on the use of medicine plants is solely aquired by oral tradition. Respondents listed total of 31 plant species that are used in the treatment, also described a method of preparing a preparations and its use. The most commonly used plant species or the ones provided by the largest number of respondents are yarrow, chamomile, sage, common houseleek, howthorn and cabbage. The most common preparation applied is tea (infusion and decoction) and the most common indications are stomach and heart ailments, various inflammation and swelling. Comparing application in the traditional use and scientific knowledge it is possible to conclude that the application of the majority of plant species for the purpose stated by respondents is scientifically justifield and are used today in modern phytopharmacy.