Preoperatory in non cardiac surgery

Patients undergoing non-cardiac surgery and who have coronary artery disease run a high risk of myocardial infarct. Diagnosis and postoperative management is presently based on assessment of cardiac troponin I. Associated with optimal postoperatory management, several approaches can limit the occurrence of postoperatory coronary complications and improve the life expectancy of surgical patients with high cardiovascular risk. They include the possibility of preoperatory myocardial revascularisation and the prophylactic, postoperatory administration of cardiovascular medications (non-steroidal anti-inflammatory drugs, beta-blockers and alpha 2 receptor agonists)...

INTRODUCTION AND OBJECTIVES: After the ischemia-reperfusion process in extracorporeal cardiac surgery there are, among several phenomena, some reperfusion arrhythmias which are influenced by a varied series of mechanisms. These arrhythmias have been related to the release of oxygen-derived free radicals during the first moments of reperfusion. Thus, a previous administration of free-radical scavengers might be beneficial, among which captopril has been included with good results in human studies in vitro and in animals in vivo...