Phys.org news tagged with:cancerous cellshttp://phys.org/
en-usPhys.org internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine.Gold-diamond nanodevice for hyperlocalised cancer therapyPrecise targeting biological molecules, such as cancer cells, for treatment is a challenge, due to their sheer size. Now ,Taiwanese scientists have proposed an advanced solution, based on a novel combination of previously used techniques, which can potentially be applied to thermal cancer therapy. Pei-Chang Tsai from the Institute of Atomic and Molecular Sciences, at the Academia Sinica, Taipei, and colleagues just published in EPJ QT an improved sensing technique for nanometre-scale heating and temperature sensing. Using a chemical method to attach gold nanorods to the surface of a diamond nanocrystal, the authors have invented a new biocompatible nanodevice. It is capable of delivering extremely localised heating from a near-infrared laser aimed at the gold nanorods, while accurately sensing temperature with the nanocrystals.http://phys.org/news/2015-07-gold-diamond-nanodevice-hyperlocalised-cancer-therapy.html
Bio & Medicine Fri, 31 Jul 2015 10:40:01 EDTnews357557456Researchers discover that aspartate is a limiter of cell proliferationMitochondria are well known for their role as powerhouses in our cells, using respiration to release the energy in the food we eat and trapping that energy in the molecule adenosine triphosphate, or ATP.http://phys.org/news/2015-07-aspartate-limiter-cell-proliferation.html
Cell & Microbiology Thu, 30 Jul 2015 13:18:54 EDTnews357481083Transforming living cells into tiny lasersIn the last few decades, lasers have become an important part of our lives, with applications ranging from laser pointers and CD players to medical and research uses. Lasers typically have a very well-defined direction of propagation and very narrow and well-defined emission color. We usually imagine a laser as an electrical device we can hold in our hands or as a big box in the middle of a research laboratory.http://phys.org/news/2015-07-cells-tiny-lasers.html
Optics & Photonics Tue, 28 Jul 2015 06:16:36 EDTnews357282986Researchers feed white blood cells micro-lasers causing them to produce lightA team of researchers working at the University of St Andrews in Scotland has found a way to place a laser inside a living human cell. In their paper published in the journal Nano Letters, the team describes their technique and the ways in which the new procedure may be used for future medical applications.http://phys.org/news/2015-07-white-blood-cells-micro-lasers.html
Optics & Photonics Thu, 23 Jul 2015 08:30:02 EDTnews356851998Cancer biologists find a key that may unlock how tumors form and progressAn international team of scientists, led by a Virginia Tech researcher, determined that the number of chromosomes in a cell may be a key to understanding how cancer forms and progresses – a finding that could help inform new treatments.http://phys.org/news/2015-07-cancer-biologists-key-tumors.html
Cell & Microbiology Wed, 22 Jul 2015 07:50:01 EDTnews356765968Researchers aiming to produce vaccine to save the Tasmanian devilNew research, led by University of Southampton biological scientist Dr Hannah Siddle, is aiming to develop an effective vaccine against an infectious cancer that is eradicating the Tasmanian devil, the world's largest remaining marsupial carnivore.http://phys.org/news/2015-07-aiming-vaccine-tasmanian-devil.html
Plants & Animals Tue, 21 Jul 2015 08:10:01 EDTnews356683668New techniques improve specificity of CRISPR/Cas9 genome editing toolsTo overcome the off-target mutations that commonly occur with CRISPR/Cas9 genome editing methods, researchers at Harvard Medical School and Massachusetts General Hospital have developed two strategies that greatly improve the specificity of RNA-guided nucleases for the DNA region targeted to be cut and repaired. A description of these new techniques and their successful use to modify human cancer cells and embryonic stem cells is described in a special issue on genome editing in Human Gene Therapy.http://phys.org/news/2015-07-techniques-specificity-crisprcas9-genome-tools.html
Biotechnology Mon, 20 Jul 2015 13:43:20 EDTnews356618591Imaging glucose uptake activity inside single cellsResearchers at Columbia University have reported a new approach to visualize glucose uptake activity in single living cells by light microscopy with minimum disturbance. In a recent study published in Angewandte Chemie International Edition [1], Associate Professor of Chemistry Wei Min's team developed a new glucose analogue that can mimic the natural glucose, and imaged its uptake as energy source by living cancer cells, neurons and tissues at the single cell level.http://phys.org/news/2015-07-imaging-glucose-uptake-cells.html
Biochemistry Fri, 17 Jul 2015 17:31:49 EDTnews356373098Yeast key to understanding cell divisionA team of scientists has discovered that a protein in common baker's yeast helps control cell division – findings that may have implications for understanding diseases such as cancer.
A protein called Yih1, for Yeast Homologue of the mammalian protein IMPACT, was studied by researchers from Massey University, Brazil's Universidade Federal de São Paulo and Upstate Medical University in New York, who found it plays a role in cell division.http://phys.org/news/2015-07-yeast-key-cell-division.html
Cell & Microbiology Thu, 16 Jul 2015 08:10:01 EDTnews356247511Magnetic nanoparticles could be key to effective immunotherapyIn recent years, researchers have hotly pursued immunotherapy, a promising form of treatment that relies on harnessing and training the body's own immune system to better fight cancer and infection. Now, results of a study led by Johns Hopkins investigators suggests that a device composed of a magnetic column paired with custom-made magnetic nanoparticles may hold a key to bringing immunotherapy into widespread and successful clinical use. A summary of the research, conducted in mouse and human cells, appears online July 14 in the journal ACS Nano.http://phys.org/news/2015-07-magnetic-nanoparticles-key-effective-immunotherapy.html
Bio & Medicine Wed, 15 Jul 2015 09:54:17 EDTnews356172849Nanospheres shield chemo drugs, safely release high doses in response to tumor secretionsScientists have designed nanoparticles that release drugs in the presence of a class of proteins that enable cancers to metastasize. That is, they have engineered a drug delivery system so that the very enzymes that make cancers dangerous could instead guide their destruction.http://phys.org/news/2015-07-nanospheres-shield-chemo-drugs-safely.html
Bio & Medicine Tue, 14 Jul 2015 14:06:47 EDTnews356101599Researchers achieve first total synthesis of cancer-killing shishijimicin ARice University scientists have achieved the total synthesis of a scarce natural marine product that may become a powerful cancer-fighting agent – the molecule shishijimicin A.http://phys.org/news/2015-07-total-synthesis-cancer-killing-shishijimicin.html
Biochemistry Tue, 14 Jul 2015 06:38:32 EDTnews356074697How intracellular signaling regulates growth factor productionCancer cells need life-essential molecules to proliferate. These so-called growth factors are activated by ectodomain shedding of precursor proteins on the outside of the plasma membrane, mainly carried out by three human cleavage enzymes. A pharmaceutical blocking of these enzymes could hinder cancer from growing but would also inhibit other life-essential processes. Now, researchers from German Leibniz Institute for Age Research (FLI) and Harvard University, US, showed that the factor-precursor-producing cells themselves determine if and when cleavage may occur. This is decided by intracellular signaling. Interfering with defined signaling in cells producing cancer growth factors could be developed into a new way of cancer treatment.http://phys.org/news/2015-07-intracellular-growth-factor-production.html
Biochemistry Fri, 10 Jul 2015 08:20:01 EDTnews355732974Cell structure discovery advances understanding of cancer developmentUniversity of Warwick researchers have discovered a cell structure which could help scientists understand why some cancers develop.http://phys.org/news/2015-07-cell-discovery-advances-cancer.html
Cell & Microbiology Fri, 10 Jul 2015 06:54:55 EDTnews355730085Microfabricated device allows evaluation of the efficacy, toxicity of pro-drugsA team of researchers from the Massachusetts General Hospital Center for Engineering in Medicine (MGH-CEM) has developed a novel approach that dramatically simplifies the evaluation of the liver's drug-metabolizing activity and the potential toxic effects of the products of that activity on other organs. Their report appears in the forthcoming issue of the journal Technology.http://phys.org/news/2015-07-microfabricated-device-efficacy-toxicity-pro-drugs.html
Analytical Chemistry Tue, 07 Jul 2015 10:15:07 EDTnews355482898How cancer cells avoid shutdownA mechanism beyond the level of gene regulation, which is often the underlying reason for changes in protein levels, does enable the strong accumulation of a tumour promoting protease in stressed cancer cells. The group of BIOSS researcher Prof. Dr. Thomas Reinheckel teamed up with BIOSS investigator Prof. Dr. Sabine Rospert and their colleagues from the University Medical Center Freiburg, Prof. Dr. Elmar Stickeler and Dr. Peter Bronsert, in order to unravel mechanisms by which stress-resistant production of cancer promoting proteins occurs. They published their research findings in the Journal of Biological Chemistry.http://phys.org/news/2015-07-cancer-cells-shutdown.html
Biochemistry Mon, 06 Jul 2015 09:20:01 EDTnews355391898Scientists use nanoparticles to shut down mechanism that drives cancer growthWhen scientists develop cancer therapies, they target the features that make the disease deadly: tumor growth, metastasis, recurrence and drug resistance. In epithelial cancers—cancers of the breast, ovaries, prostate, skin and bladder, which begin in the organs' lining—these processes are controlled by a genetic program called epithelial–mesenchymal transition.http://phys.org/news/2015-07-scientists-nanoparticles-mechanism-cancer-growth.html
Bio & Medicine Fri, 03 Jul 2015 05:32:48 EDTnews355120359Hippo dances with hormones: Hints from fly research for study of cancer, stem cellsAlthough fruit flies don't develop cancer, cancer and stem cell researchers have been learning a great deal from fruit flies - in particular, mutant flies with overgrown organs that resemble hippopotamuses.http://phys.org/news/2015-07-hippo-hormones-hints-cancer-stem.html
Cell & Microbiology Thu, 02 Jul 2015 12:00:10 EDTnews355051637New technique maps elusive chemical markers on proteinsUnveiling how the 20,000 or so proteins in the human body work—and malfunction—is the key to understanding much of health and disease. Now, Salk researchers developed a new technique that allows scientists to better understand an elusive step critical in protein formation.http://phys.org/news/2015-07-technique-elusive-chemical-markers-proteins.html
Cell & Microbiology Thu, 02 Jul 2015 12:00:05 EDTnews355051315Scientists advance cancer drug design with image of key proteinScientists have pioneered the use of a high-powered imaging technique to picture in exquisite detail one of the central proteins of life – a cellular recycling unit with a role in many diseases.http://phys.org/news/2015-07-scientists-advance-cancer-drug-image.html
Biochemistry Thu, 02 Jul 2015 06:38:05 EDTnews355037875Chitosan coated, chemotherapy packed nanoparticles may target cancer stem cellsNanoparticles packed with a clinically used chemotherapy drug and coated with an oligosaccharide derived from the carapace of crustaceans might effectively target and kill cancer stem-like cells, according to a recent study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James).http://phys.org/news/2015-06-chitosan-coated-chemotherapy-nanoparticles-cancer.html
Bio & Medicine Tue, 30 Jun 2015 11:17:01 EDTnews354881812Atomic force microscope advance leads to new breast cancer researchResearchers who developed a high-speed form of atomic force microscopy have shown how to image the physical properties of live breast cancer cells, for the first time revealing details about how deactivation of a key protein may lead to metastasis.http://phys.org/news/2015-06-atomic-microscope-advance-breast-cancer.html
Bio & Medicine Tue, 30 Jun 2015 09:06:36 EDTnews354873987Stanford team develops technique to magnetically levitate single cellsRemember the levitating frog? That feat—the levitation of a live frog using a powerful magnet—was awarded the 2000 Ig Nobel Prize. Fascinating to watch, the demonstration also cemented a longstanding belief that levitating anything smaller than 20 microns was flat-out impossible. Much less something alive.http://phys.org/news/2015-06-stanford-team-technique-magnetically-levitate.html
Cell & Microbiology Tue, 30 Jun 2015 05:56:53 EDTnews354862593Eavesdropping on the body: New device tracks chemical signals within cellsBiomedical engineers at the University of Toronto have invented a new device that more quickly and accurately "listens in" on the chemical messages that tell our cells how to multiply. The tool improves our understanding of how cancerous growth begins, and could identify new targets for cancer medications.http://phys.org/news/2015-06-eavesdropping-body-device-tracks-chemical.html
Analytical Chemistry Wed, 24 Jun 2015 08:20:04 EDTnews354352794Single enzyme's far-reaching influence in human biology and diseaseEvery cell in the body uses phosphorylation, the process of adding a chemical tag to control a protein's function and fate, such as when it moves from one part of a cell to another or binds to other proteins.http://phys.org/news/2015-06-enzyme-far-reaching-human-biology-disease.html
Cell & Microbiology Thu, 18 Jun 2015 12:00:10 EDTnews353846547Toward nanorobots that swim through blood to deliver drugsSomeday, treating patients with nanorobots could become standard practice to deliver medicine specifically to parts of the body affected by disease. But merely injecting drug-loaded nanoparticles might not always be enough to get them where they need to go. Now scientists are reporting in the ACS journal Nano Letters the development of new nanoswimmers that can move easily through body fluids to their targets.http://phys.org/news/2015-06-nanorobots-blood-drugs.html
Bio & Medicine Wed, 17 Jun 2015 18:59:08 EDTnews353786339Researcher uses microscale technology to isolate rare cellsIn a blood sample taken from a cancer patient, there may be a single circulating tumor cell among hundreds of thousands of other cells. These tumor cells can provide valuable information about how cancer progresses, and could help doctors decide how to treat individual patients, but they are extremely difficult to find.http://phys.org/news/2015-06-microscale-technology-isolate-rare-cells.html
Biochemistry Wed, 17 Jun 2015 08:33:04 EDTnews353748772Nanoparticles target and kill cancer stem cells that drive tumor growthMany cancer patients survive treatment only to have a recurrence within a few years. Recurrences and tumor spreading are likely due to cancer stem cells that can be tough to kill with conventional cancer drugs. But now researchers have designed nanoparticles that specifically target these hardy cells to deliver a drug. The nanoparticle treatment, reported in the journal ACS Nano, worked far better than the drug alone in mice.http://phys.org/news/2015-06-nanoparticles-cancer-stem-cells-tumor.html
Bio & Medicine Wed, 10 Jun 2015 12:05:09 EDTnews353156699Researchers identify unique marker on mom's chromosomes in early embryoResearchers in the University of Georgia's Regenerative Bioscience Center are visually capturing the first process of chromosome alignment and separation at the beginning of mouse development. The findings could lead to answers to questions concerning the mechanisms leading to birth defects and chromosome instability in cancer cells.http://phys.org/news/2015-06-unique-marker-mom-chromosomes-early.html
Biotechnology Tue, 09 Jun 2015 06:24:36 EDTnews353049843New map uncovers the traffic of life in a cellToronto scientists have recorded, in unprecedented detail, the locations of all proteins in a cell. This new protein map allows scientists to look much more closely into what happens in a cell when disease strikes, and will also help find better treatments.http://phys.org/news/2015-06-uncovers-traffic-life-cell.html
Cell & Microbiology Mon, 08 Jun 2015 07:00:01 EDTnews352963404