DNASTAR NovaFold

Software for Structure Prediction

DNASTAR NovaFold is protein structure prediction software that is based on I-TASSER, the award-winning software package developed by Prof. Yang Zhang's laboratory at the University of Michigan. NovaFold utilizes the I-TASSER algorithms developed by Prof. Zhang that combine threading and ab initio folding technologies to build accurate, full 3D atomic models of proteins with previously unknown structures. NovaFold is available as an add-on to Protean 3D.

“I recently had an opportunity to try NovaFold for several protein structure predictions. I was impressed by how well the predicted models fit my expectation. Visualization of the structures in Protean 3D is also beautiful and easy to work with. My ability to evaluate and modify the structures as necessary is made very easy in your software.”

– Samir Naimov DSc, University of Plovdiv "Paisii Hilendarski"

Features & Highlights

Predict 3D Structure Based on Protein Sequence

Use NovaFold’s hybrid method of protein structure prediction to yield highly accurate models. This approach first identifies structural fragments by comparing them to a template library, then incorporates both these and the unmatched fragments into the final structure

Predict ligand binding sites and protein function

Assess NovaFold prediction quality through support of structure and sequence alignment