High frequency of mutations that expand the host range of an RNA virus.

This paper sheds new light on one of the most important questions in viral emergence; how rapidly RNA viruses are able to generate mutations that allow them to adapt to new host species. Using an experimental analysis of an RNA bacteriophage as a model system, the authors show that mutations that expand host range are a remarkably abundant component of viral genetic diversity.

The major implication of this study is therefore...

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