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Abstract:

In Brief:

Macular hole retinal detachment in highly myopic eyes is one of the most difficult types of retinal detachment to treat, and its primary treatment choice is still controversial, although the different surgical techniques reported in this review have been demonstrated as good surgical options. Randomized clinical trials are largely lacking.

Abstract:

In Brief:

A high proportion of eyes with internal limiting membrane peeling develop inner retinal dimples that course along the path of the nerve fiber layer. The dimples seem to be the result of an interplay between trauma and healing processes constrained by nerve fiber layer and does not appear to be because of dissociation of optic nerve fibers. The true nature of the abnormalities induced should be investigated to evaluate the long-term risks and benefits of routine internal limiting membrane peeling.

Abstract:

In Brief:

Continuous anatomical and functional improvements can be observed after successful microinvasive macular hole surgery. The preoperative extent of the inner/outer segment defect is of good predictive value for postoperative macular sensitivity. However, the factors that influence best-corrected visual acuity are multiple. Prediction of best-corrected visual acuity based on a single anatomical parameter or the assessment of macular function only based on best-corrected visual acuity should be avoided.

Abstract:

In Brief:

In patients with central visual loss from lamellar macular holes, vitrectomy, membranectomy, and/or internal limiting membrane peeling and gas tamponade appear to have a beneficial effect for a mean of 3 years.

Abstract:

In Brief:

We describe the results of vitrectomy for retained lens fragments after phacoemulsification of 89 consecutive cases. Retinal breaks were identified intraoperatively in 29% of cases. Prophylactic treatment of breaks and other areas of retinal traction seem to reduce the risk of postoperative retinal detachment.

Abstract:

In Brief:

In patients with diabetes, choroidal thickness (both macular and peripapillary) progressively decreases with increasing level of diabetic retinopathy with specific patterns. Peripapillary choroidal thickness is significantly thinner than macular choroidal thickness. The role of choroid in the pathophysiology of diabetic retinopathy should be investigated using spectral domain optical coherence tomography.

Abstract:

In Brief:

Sleep disordered breathing is highly prevalent in individuals with clinically significant macular edema. There are several potential theoretical reasons for this. However, the mechanism of any potential causal relationship remains unclear. Further work is required to assess whether treating individuals with concurrent sleep disordered breathing and clinically significant macular edema improves vision. Given this high prevalence, retinal specialists should consider referring patients with clinically significant macular edema for screening for sleep disordered breathing.

Abstract:

In Brief:

The present study reports the use of intravitreal ranibizumab during cataract surgery in patients with diabetic macular edema nonresponsive to laser therapy. In this case series, ranibizumab during cataract surgery was associated with no significant change in macular thickness postoperatively.

Abstract:

In Brief:

We prospectively compared the injection frequency of intravitreal ranibizumab for wet age-related macular degeneration in Japanese with or without topical bromfenac, a nonsteroidal antiinflammatory drug, and found that the adjunctive bromfenac might reduce the injection frequency of ranibizumab during the early phase of treatment.

Abstract:

In Brief:

Prompt intravitreous bevacizumab treatment for newly diagnosed exudative age-related macular degeneration in patients with good initial visual acuity (≥20/40) is associated with sustained or improved vision and a good safety profile.

Abstract:

In Brief:

This analysis provided some evidence, although not definitive, of a potential increased risk of cerebrovascular accident with ranibizumab versus control or with 0.5-mg versus 0.3-mg ranibizumab. Continued monitoring for cerebrovascular accident within clinical trials seems warranted.

Abstract:

In Brief:

We describe clinical and multimodal imaging findings of patients with Type 1 neovascularization believed to be secondary to long-standing central serous chorioretinopathy (CSC). These patients tend to be younger, men, and appear to have a higher prevalence of polypoidal neovasculopathy than those with neovascular age-related macular degeneration. Choroidal hyperpermeability and chronic retinal pigment epithelial disease may predispose to the development of Type 1 neovascular tissue in patients with CSC.

Abstract:

In Brief:

Aqueous flare intensity after vitrectomy for retinal detachment decreased to a stable level at 3 months postoperatively but remained significantly higher than the normal level. The size of retinal breaks and the degree of surgical invasion were associated with the increase in aqueous flare.

Abstract:

In Brief:

Peribulbar anesthesia for vitreoretinal surgery can probably be performed safely in patients receiving anticoagulants. However, antiplatelet agents can lead to potentially sight-threatening complications.

Abstract:

In Brief:

This article represents the changes of macular microstructures before and after silicone oil removal by spectral-domain optical coherence tomography. Under silicone oil tamponade, epiretinal membrane, macular edema, undulated inner retina, submacular fluid, and the integrity of photoreceptor layer and external limiting membrane were demonstrated. After silicone oil removal, most of the tomographic changes were recovered.

Abstract:

In Brief:

Regions of geographic atrophy were measured in eyes with age-related macular degeneration using both color fundus photographs and fundus autofluorescence images. Agreements in geographic atrophy area between the different imaging modalities and between different graders were assessed, and reasons for disagreement were identified.

Abstract:

In Brief:

ASPPC is an uncommon but clinically and angiographically distinct manifestation of ocular syphilis. All patients with characteristic clinical and angiographic findings of ASPPC should be tested for both neurosyphilis and human immunodeficiency virus coinfection. Vision recovery typically followed completion of appropriate antibiotic therapy.

Abstract:

In Brief:

The authors' 3-generation family with pattern dystrophy was positive for Y141C mutation in peripherin/RDS gene and manifested a high intrafamilial variability of phenotype. The proband with multifocal pattern type developed choroidal neovascularization, which responded to anti–vascular endothelial growth factor treatment (ranibizumab), with complete anatomical and functional recovery (visual acuity 20/20) after 4 injections.

Abstract:

In Brief:

Bilateral diffuse uveal melanocytic proliferation is a paraneoplastic condition characterized by proliferation of uveal melanocytes. We show that cultured melanocytes and melanoma cells proliferate once they are exposed to the serum or plasma of these patients. The activity appears to be concentrated in the IgG fraction.

Abstract:

In Brief:

In this study, a significant association of the pi isoform of glutathione S-transferase (GSTP1) variant rs1695 was found with exudative age-related macular degeneration in a sample of Chinese population.

Abstract:

In Brief:

We evaluated the relationship between retinal structures and macular sensitivity in eyes with idiopathic macular telangiectasia type 1. Retinal sensitivity is influenced not only by intraretinal cystoid spaces but also by photoreceptor disruptions, and the photoreceptor alterations reduce the visual function more severely.