In this thesis, evolutionary models are developed for protein coding sequences of the human immunodeficiency virus (HIV). These models are applied to predict the epitopes targeted by the cell-mediated and humoral arms of ...

This paper discusses the use of a Genetic Algorithm (GA) to evolve waypoint-based racing lines for computer-controlled cars in an online game. One goal is the reduction of developer effort, in order to automatically produce ...

This project investigated the therapeutic potential of allo-antigen specific regulatory
T-cells in the context of penetrating keratoplasty. Two methods of ex-vivo generation
of T regulatory cells have been explored in ...

This thesis deals with the determination of the most suitable methods of finding the food magnitude-return period relationship for Irish flood data using the annual maximum statistical model. Data from approximately 200 ...

The current study used multi-group structural equation modelling (SEM) to test a fully
and partially mediated Extended Rational Model of Work-Life Conflict and examine
the impact of job involvement, workaholism, work ...

This is the first dedicated and comprehensive study of glass beads from Early Medieval Ireland, presenting the first national classification, typology, dating and consideration of the social context and symbology of glass ...

In regional flood frequency estimation, a homogeneous pooling group of sites leads to a reduction in the error of quantile estimators which is the main aim of a regional flood frequency analysis. Examination of the homogeneity ...

Autism Spectrum Disorders (ASD) are neurodevelopmental disorders that are often associated with a broad range of difficulties and challenges for the individual. Parents of children with ASD often experience higher levels ...

Argument mapping (AM) is a method of visually diagramming arguments to allow for easy comprehension of core statements and relations. A series of three experiments compared argument map reading and construction with ...

McDaniel, Bill; Kruk, Sebastian Ryszard(Association for the Advancement of Computing in Education, 2007)

eLearning has, to date, mostly been a matter of content being displayed on PCs running Windows, Linux, or MAC OS. Emerging technologies have recently, however, expanded the capabilities and scope of portable and mobile ...

The primary aim of this thesis is to critically examine the interactions between the real and financial economy, particularly in the context of financialisation, and its implications for the transmission of monetary policy. ...

Research from numerous countries across the world indicates that academics are experiencing high levels of occupational stress and trends indicate that stress levels are increasing over time. Two stressors which have been ...

A key feature of progressive myeloma is a relative increase in proliferation. The DBF4-dependent kinase (DDK), cell division cycle 7 (CDC7), is an essential kinase for initiation of DNA replication. This thesis assesses ...

While an acute, continuous focus on customer needs is often cited as a key benefit of agile approaches, very little research has examined the customer focus construct in an agile project environment, or looked at the ...

We present evidence of phase transitions (periodic to chaotic and
chaotic to chaotic) in the Dow Jones Industrial Index as it transitions
from Bull to Bear market. There is also evidence of a completely unpredictable
(i.e., ...

The partial excavation of the embanked mound and standing stone known as 'Dathi's Mound' at the royal site of Rathcroghan, Co. Roscommon, confirmed that the mound had been cut from a natural gravel ridge. It also revealed ...

We consider exceptional vertex operator algebras for which particular Casimir vectors constructed from the primary vectors of lowest conformal weight are Virasoro descendants of the vacuum. We discuss constraints on these ...

The TeV binary system LS I +61 degrees 303 is known for its regular, non-thermal emission pattern that traces the orbital period of the compact object in its 26.5 day orbit around its B0 Ve star companion. The system ...

The Chalcolithic and Early Bronze Age (EBA) in Ireland were periods of great flux, out of which and into which, novel technologies and institutions emerged and were transmitted. This thesis combines analysis of the material ...