Thunderbird Portable - Crash with Wine

Dear Forum,

there's a problem with Wine concerning Thunderbird Portable, the standalone version of Mozilla Thunderbird. As probably experienced by many other users, a few seconds after the opening of Thunderbird this suddenly closes, and a Wine error message appears.

This situation has been going on for months (more than a year, in truth), and prevents me from using Ubuntu itself, because an important part of the time I spend in front of the computer is usually dedicated just to the management of my e-mails and contacts.

Does anyone knows more about how to solve this problem?

Are there any other applications able to substitute for Wine, doing its same work?