Application Information: EGF antibody [S-147]

ELISA: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.

Concentration

1
mg/ml
(Please refer to the vial label for the specific concentration)

Purification

Protein G purified

Specifications: EGF antibody [S-147]

Full Name

epidermal growth factor

Product Description

Mouse monoclonal [S-147] to EGF

Background

EGF exerts its actions by binding to the EGFR, a 170 kDa protein. Activation of EGFR initiates diverse cellular pathways in response to toxic environmental stimuli, or to EGF binding to the receptor, the EGFR forms homo- or heterodimers with other family members. Each dimeric receptor complex initiates a distinct signaling pathway by recruiting different Src homology 2 (SH2) containing effector proteins.

Synonyms

P01133, 1950, URG, 131530, EGF

Cellular Localization

Secreted

Specificity

Reactive with natural and recombinant Human EGF but does not react with other human cytokines tested (IL 1beta, IL 8, MCAF, TGF beta and SAA).

Host

Mouse

Clonality

Monoclonal

Clone Name

S-147

Target

EGF

Isotype

IgG1

Immunogen

Purified recombinant human EGF. 6kDA, 53 amino acid residues

Light Chain

kappa

Antigen Species

Human

Species Reactivity

Human

Storage Conditions: EGF antibody [S-147]

Storage Buffer

Preservative: None. Constituents: 0.01M PBS. pH 7.2

Storage Instruction

Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.

Notes

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.