Dr. Malek completed studies at the University of Michigan School of Dentistry. In the late 1980s, he founded Dental Pride, Inc., as a practice dedicated to addressing unmet dentistry needs in the community. He pioneered the use of digital patient radiographic records in creating a paperless office environment.

From 2005 to 2013, he led Smile Spa in Tucson, Arizona, which featured 10 operatories in combination with a wellness and rejuvenation center and med spa. The practice emphasized affordability while delivering-leading edge care that featured the latest technologies. Mickel Malek, DDS, maintained a strong community presence in Tucson and helped sponsor an annual Boys and Girls Club fundraiser.