THEAL Therapy

Unlocking the Body's Own Healing Potential

Light is the basis of life.

The same plants grow and bloom with the help of light energy. Likewise, the bright energy of THEAL Therapy, an innovative patented phototherapy based on advanced laser technology, allows the interaction with biological tissues by triggering the metabolic reactions essential to accelerate the process of natural healing. The THEAL Therapy photons, when interacting with biological tissues, release their energy to the cells by allowing them, through the action of the chromophores, to transform it into other forms of energy in order to support the photobiomodulation at the base of all metabolic processes. The photobiomodulation, at the base of metabolic activities, is triggered by the selective and naturally thermal laser light absorption, which provides three fundamental effects: tissue regeneration, inflammatory action modulation and analgesic effect.

Mechanism of Low Level Laser Therapy - Hamblin 2006

Not all laser radiations allow to activate the photobiomodulation and obtain therapeutic effects. In fact, it should be emphasized that laser light that obtains therapeutic effects must be able to exchange energy with biological tissues, while at the same time transforming it into other forms of biocompatible energy through the action of the chromophores. This process, through a careful choice of laser emission parameters, can be optimized, avoiding leakage due to passive chromophore (water, melanin, hemoglobin and hemoglobin oxide), thus promoting cellular respiration. This process is only possible through the selective absorption of specialized chromophores. The laser light that maximizes these processes and achieves therapeutic effects must belong to the therapeutic window.

The therapeutic window was defined by Hamblin in 2006 in the article "Mechanism of Low Level Laser Therapy".

The therapeutic window is a range of wavelengths not overly absorbed by the major passive human chromophore, a range of wavelengths that allow to penetrate into biological tissues to exchange energy with them. This range of wavelengths is between 600nm and 1100nm. The wavelengths in the therapeutic window are not absorbed by the main chromophores in the same way and thus have a different penetration capacity within biological tissues. The ability to penetrate in the biological tissues is a function of both wavelength and power. At equal power, the wavelength that allows to penetrate better in the biological tissues is 830nm.

The ability of the laser light to penetrate deep is certainly very important, but not sufficient, indeed, as the first law of photochemistry “Light must be absorbed before photochemistry can occur”, is much more important the ability of the laser light to interact and to be absorbed by biological tissues.
All wavelengths within the therapeutic window (600nm - 1100nm) allow to interact with biological tissues by triggering photobiomodulation processes, but it has been shown that some of them are definitely more effective. It is scientifically proven that the main cellular chromophore of photobiomodulation is the Cytochrome C oxidase, an enzyme present within the mitochondria, cellular organelles present within each cell of the human body.

Cell

MitocHONDRION

CYTOCHROME

Numerous recent scientific articles like “Re-evaluation of the near infrared spectra of mitochondrial cytochrome c oxidase: Implications for non invasive in vivo monitoring of tissues” (G.Mason, P. Nicholls, E. Cooper – 2014) and “Multiple Roles of Cytochrome c Oxidase in Mammalian Cells Under Action of Red and IR-A Radiation”(T. Karu - 2010) have demonstrated that the laser light in the visible red, such as that at 650nm, and the laser light in the range of 800nm - 850nm, are those most absorbed by the Cytochrome C Oxidase, enabling to trigger the photobiomodulation in the best possible way.

For this reason all devices capable of implementing the THEAL Therapy are equipped with two wavelengths highly absorbed by the Cytochrome C Oxidase: 650nm and 810nm. In particular, THEAL Therapy emits 650nm laser light up to 2W (2000mW) power.

Between the wavelengths emitted by the main devices for THEAL therapy there are also 980nm and 1064nm. These two wavelengths while being less absorbed by the Cytochrome C Oxidase have other features which maximize the therapeutic results triggered by photobiomodulation.
Both wavelengths, in particular the 980nm, are absorbed by the water and allow to generate both a good photothermal effect and an excellent photomechanical effect when the emission is characterized by pulse trains.
In addition, the 1064nm wavelength, thanks to its greater depth of action than the 980nm and the smaller scattering, has more directional action and greater power density at the same power level.

The 980nm and 1064nm wavelengths allow to optimize the action on the thermal and mechanical receptors and, when combined with the E²C mode, ensure the right interaction with the peripheral nervous system, activating the Gate Control mechanism for a quick analgesic effect.
Due to these peculiarities, these two wavelengths trigger further metabolic pathways that may act in some cases at the same time as those triggered by photobiomodulation.

THEAL Therapy not only has all the wavelengths necessary to trigger photobiomodulation and action on the thermal and mechanoreceptors, but allows them to be synergized and uncompetitive between them, and to associate with each wavelength different emission modes, in order to maximize the therapeutic result for the specific patient and the specific pathology.

It should be further emphasized that to trigger the photochemical effect of photobiomodulation is necessary that the whole process takes place without an excessive increase in tissue temperature. Therefore, the patented thermal control system of the biological tissues is present in the THEAL Therapy devices. This system enables the photobiomodulation to be activated in optimum conditions by selecting the thermal thresholds within which to perform the therapy.

In addition it has been demonstrated that the optimal laser emission to trigger photobiomodulation must be continuous or pulsed with a pulse duration of at least a few milliseconds, as stated by Hamblin, in 2010 in the article "Effect of Pulsing in Low-Level Light Therapy" and a dark period between two pulses between 50ms and 200ms, as stated by T. Karu in 2001 in the article "Studies in the Action Specifics of a Pulsed GaalAs Laser (ʎ = 820nm) on a Cell Culture".

The main emission modes in THEAL Therapy meet the criteria needed to trigger photobiomodulation.

THEAL Therapy is designed based on all the most important and recent scientific research on phototherapy and is equipped with wavelengths fundamental to trigger photobiomodulation and action on thermal and mechanoreceptors and allows to be mixed together in order to adapt to the specific patient and the specific pathology. It is also equipped with multiple emission modes, a wide range of applicators and thermal control of biological tissues in order to optimize the maximum compliance and therapeutic results. Acute, chronic pain, edema, lesions, wounds and musculoskeletal disorders are a distant memory. Thanks to the adaptive phototherapy of THEAL Therapy it is possible to maximize therapeutic performance on patients with different pathophysiological characteristics.

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