Authorities said the men, both in their 20s, were in a vehicle traveling southbound on Kaneohe Bay Drive around 8 p.m. when they collided with another car that was trying to make a left onto Makalani Street.

Both men were rushed to the Queen’s Medical Center in critical condition. The driver of the other car, a man in his late 40s, suffered serious injuries.

Police said speed appears to be a factor in the crash.

Officers shut down the road for several hours during the investigation.