Job cuts will include administrators and back-office staff including billing and clinical employees who don’t work with patients

MD Anderson Cancer Center said it would cut 800 to 900 jobs, or about 5% of its workforce, as the globally renowned Texas hospital struggles with financial losses.

Chief Financial Officer Dan Fontaine attributed the losses to a drop in physician productivity as the Houston-based hospital began using new electronic health records last year. Doctors took time away from patients to learn the new computerized system, and continue to...