Domitius was thus related to several notable figures who would dominate the Roman Empire during the 1st century. Suetonius describes him as ‘despicable and dishonest’. As a young man, Domitius was serving on the staff of his second cousinGaius Caesar in the East. Gaius was a son of Marcus Vipsanius Agrippa and Julia the Elder, daughter to the previously mentioned Augustus. Domitius fortified their friendship by killing his freedman for refusing to drink as much as he was told.[2] The reported reason was that the freedman did not get as drunk as Domitius did. On the Appian Way, Domitius was reported of having deliberately run over a child who was playing with his doll. At the Roman Forum, Domitius reportedly pulled out an eye of an equestrian because the equestrian openly criticized him.

Domitius cheated on bankers for purchases he made. When he was Praetor, Domitius would swindle the prizemoney of victorious charioteers. Managers would complain, but Domitius decreed that future prizes would be paid on the spot. Domitius was also considered a serious womanizer. The Emperor Tiberius charged him with treason, adultery and incest with his sister and also with adultery with another noblewoman, but the ascension of Caligula saved him.

Domitius married his second cousin Agrippina the Younger, Caligula's sister, after her thirteenth birthday in 28. He was 45 years old at the time. Tiberius arranged and ordered the marriage which was celebrated in Rome. Domitius was wealthy but apparently he and Agrippina chose to live between Antium (Anzio) and Rome.

Domitius was Consul in 32 and appointed by Tiberius as a commissioner in early 37. His son Lucius Domitius Ahenobarbus, later Emperor Nero, was born on 15 December 37 in Antium. According to Suetonius, he was congratulated by his friends for the birth of his son and Domitius said any child born to him and Agrippina would have a detestable nature and become a public danger, a fact that became true during the second part of Nero's reign. When Nero castrated a boy named Sporus and married him as a wife, Suetonius quoted one Roman who lived around this time who remarked that the world would have been better off if Nero's father had married someone more like the castrated boy.[3]

He died of edema at Pyrgi (an ancient Etruscan city) in January 40. In Domitius' will, Nero inherited 1/3 of his estate. But Caligula, who was also mentioned in the will, took Nero's inheritance for himself. When Claudius became Emperor, Nero's inheritance was restored.[4][5][6][7]

During his lifetime, Domitius did not enjoy a good reputation. He was accused of being the accomplice of Albucilla in the crimes of adultery and murder, and also of incest with his sister Domitia Lepida, and narrowly escaped execution only because of the death of Tiberius.[1]

His widow Agrippina later married her widowed uncle Claudius. Lucius was adopted by the elderly Claudius as Nero Claudius Caesar Drusus Germanicus. When Claudius died on October 13, 54, Nero succeeded him as Nero Claudius Caesar Augustus Germanicus. Nero exalted Domitius’ memory and the Roman Senate arranged for the construction of his statue in 55.