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The PromethION is Oxford Nanopore Technologies' largest sequencing device, capable of delivering many terabases of data, in real time, from a single run. Hear how teams across a broad range of applications, based in labs all over the world — US (UCSF, UCD, JCVI and UCSC), China (GrandOmics and Biomarker) and Europe (KeyGene, Genescope and UMC Utrecht) — are using PromethION in their work.

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When healthy people eat a low-gluten and fibre-rich diet compared with a high-gluten diet they experience less intestinal discomfort including less bloating, a new study shows. The researchers attribute the impact of diet on healthy adults more to change in composition of dietary fibres than gluten itself.

Professor Sir Doug Turnbull from the Wellcome Trust Centre for Mitochondrial Research at the University of Newcastle explains his research into mitochondrial donation, the innovative treatment that hopes to stop faulty mitochondria being passed on from mother to child to prevent incurable genetic diseases.

The first babies conceived with this treatment through IVF may be born in the UK soon.

From their diet to their diseases, koalas are pretty special. Now researchers have sequenced the koala’s genome, unlocking the secrets that make these fuzzy fellas so unique. The genome is revealing everything from how koalas cope with munching poisonous eucalyptus leaves, to how they respond to chlamydia infections. The hope is that these insights will not only help us understand these fascinating marsupials, but also aid conservation efforts across Australia.

PLOS author John Ioannidis, Professor of Medicine, of Health Research and Policy, and of Statistics at Stanford University, considers how the scientific community can move toward greater truth in published research.