Overlapping homologous superfamilies

Family relationships

Description

Members of this radical SAM domain protein family appear to be a form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in preQ0 operons species that lack members of related protein family IPR017742.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.