It's been a long while since I've posted something about this but there still isn't any fix for this. For some reason, when enabling Vsync through the nVidia Control Panel (OFF in the nGlide options) and setting the refresh rate to any option in the nGlide options, Rayman 2 seems to have this very short rythmic stutter when the camera is moving. I noticed that when turning Vsync completely OFF, there are screen tears at the moments when the stutter used to happen. Also the stutter mainly seems to happen when the camera moves vertically (up or down). Setting the refresh rate to my own screen refresh rate doesn't help, neither does selecting another type of Vsync like Adaptive Sync.

The reason I choose not to use the Vsync option in the nGlide options itself is because it makes the movements of Rayman and other objects in the game unrealistically fast and some animations of Rayman (jumping up from hanging on a ledge) don't work properly. Here's the weird part; when using Vsync in the Glide options the stutter seems to be replaced with a weird framerate drop/worse stutter when the camera moves vertically.

The best place/level in the game which makes this bug very noticeable is in the level of The Sanctuary of Stone and Fire, particularly at the place there where you use a plum to go down a long lava stream. You'll understand what I mean if the bug is also reproduceable at your end.