Padres Preview: Padres seek third straight win in S.F.

Both could happen Saturday night in the second game of a three-game series against the Giants at AT&T Park in San Francisco (6:10 p.m.; TV: Fox Sports San Diego; Radio: 1090-AM).

But it won’t be easy. The Padres will be facing two-time National League Cy Young Award winner Tim Lincecum, who has a career 9-4 record against the Padres and was 4-1 in five starts against the Padres last season.

The Padres are 4-2 over their last six games.

The Padres bullpen leads the National League with a 2.58 earned run average. Padres relievers have already worked 66 1/3 innings, equaling the most in the National League.

PADRES (7-14) at GIANTS (10-10)

Time: 6:10 p.m. / Game 2 of 3

TV: Fox San Diego

Radio: 1090-AM; 860-AM (Spanish)

PITCHING MATCHUP

Padres RHP Anthony Bass (1-2, 2.33 ERA)

Bass vs. the Giants: 0-0 career, 0.00 ERA in four relief appearances.

Bass at AT&T Park: 0-0, 0.00 ERA in two relief appearances.

Bass, 24, is 3-1 in six career starts with a 1.78 ERA and a .204 opponents batting average. He is 1-1 in three starts this season with a 2.35 ERA. Opponents are hitting .181 against Bass this season and left-handed hitters are batting only .129 (4-for-31). He has retired the last 16 Giants he has faced and has worked 8 1/3 scoreless innings against San Francisco.

Giants vs. Bass

Brandon Crawford: .000 (0-for-3)

Aubrey Huff: .000 (0-for-1)

Tim Lincecum: .000 (0-for-1, SO)

Angel Pagan: 1.000 (1-for-1)

Brett Pill: .000 (0-for-1)

Hector Sanchez: .000 (BB)

Pablo Sandoval: .000 (0-for-3)

Nate Schierholtz: 1.000 (1-for-1)

Giants RHP Tim Lincecum (1-2, 8.20 ERA)

Lincecum vs. the Padres: 9-4 career, 1.96 ERA in 18 starts.

Lincecum at AT&T Park: 36-23 career, 3.11 ERA in 80 starts.

Lincecum, 27, won back-to-back Cy Young Awards in 2008 and 2009. He has a career 70-43 record with a 3.07 ERA, but was only 13-14 last year with a 2.74 ERA. Lincecum was 4-1 against the Padres last year with a 1.64 ERA in five starts. He is 36-23 in his career at AT&T Park with a 3.11 ERA in 80 starts.