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134; In clinical trials, patients taking Allegra reported significantly less drowsiness than those taking Zyrtec. Looks like we won––‚t be seeing much Zyrtec in our skies. According to FAA guidelines, non-sedating antihistamines may be used while flying after adequate individual experience has determined that the medication is well tolerated without significant side effects. Save On Relief. When you need a little. Allegra in your life.