The duo are in talks to star in Infinitely Polar Bear, which is set to be the directorial debut from Monsters Vs Aliens screenwriter Maya Forbes and produced by JJ Abrams.

Mark - who has been busy with The Avengers, where he is cast as the Hulk - would portray a bipolar husband and father who loses his sanity and job when he goes off his medication, and struggles to keep his marriage together, with Zoe as his long-suffering wife, reported Vulture.

Filming is set to kick off in September, before Zoe starts work on the Star Trek sequel in November.