Mice or rats receive several pre-training trials during which they are habituated to a runway to foster reliable crossing of the runway during the test. The start of the runway is brightly lit and the end contains a darkened enclosed chamber with Cocoa Krispies cereal pieces. Immediately after the pre-training sessions, footprints are recorded on a white paper on the runway floor after applying non-toxic tempera paint to the paws. Front paws are painted red and rear paws blue. Subjects are then allowed to walk down the runway, and 4 sets of footprints were collected for each animal. The footprint patterns were analyzed using the program Image J (NIH). Typical measures analyzed includ stride length, foot drags, the number of missteps, foot base and others.