Background: lipid profile disorders are important in children because they plays an important role in future cardiovascular atherosclerotic disorders. Lack of sufficient data in this regard in Fars province was the reason of performing this study.Methods: 500 healthy children were gathered from Kavar schools with systematic randomized method sampling. Body measurements and lipid profile were checked with standard methods. Data were analyzed by SPSS software.Results: We find that 35% of children have at least one abnormal lipid profile tests. 34.7% had low HDL, 7% had high total cholesterol, 13.6% had high triglyceride and 10.6% had high non HDL cholesterol. Among these abnormalities, high total and high non HDL cholesterol were more prevalent in girls. The most associated factors were body weight, height and waist circumference.Conclusion: 35% of children have at least one abnormal lipid profile tests and cholesterol disorders were more prevalent in girls. We suggest early screening, early diagnosis and treatment of these abnormalities in children which need prevention of risk factors such as obesity and inactivity.