Generic ( Methylprednisolone )

Unbound Glucocorticoids Cross Cell Membranes And Bind With High Affinity To Specific Cytoplasmic Receptors, Modifying Transcription And Protein Synthesis. By This Way, Glucocorticoids Can Inhibit Leukocyte Infiltration At The Site Of Inflammation, Interfere With Mediators Of Inflammatory Response, And Suppress Humoral Immune Responses. The Anti-inflammatory Actions Of Corticosteroids Are Thought To Involve Phospholipase A2 Inhibitory Proteins, Lipocortins, Which Control The Biosynthesis Of Potent Mediators Of Inflammation Such As Prostaglandins And Leukotrienes.

Drug Interaction of Methylprednisolone :

Methyl Prednisolone Is Known To Interact With Other Drugs Like Acetylsalicylic Acid, Clarithromycin, Conivaptan, Erythromycin, Fosphenytoin, Itraconazole, Phenytoin, Primidone. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.

INTERACTIONS OF METHYLPREDNISOLONE

How Methylprednisolone will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Methylprednisolone will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.