BMS-540215 Brivanib

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Chemical Information

Product name：BMS-540215 Brivanib

Purity：98% min

CAS NO：649735-46-6

Solubility：DMSO: ≥ 50 mg/mL

Molecular Formula：C19H19FN4O3

Package：Package according to customer requirements

Molecular Weight：370.378

Storage：Store at -20℃

Quality control

Remarks

Brivanib is the hydrolyzed form of Brivanib alaninate, which is a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression.