Holy Cow... Aegeline No More

In the article it would appear that USPLabs is not even going to bother to fight the FDA on aegeline. Apparently they've informed the FDA that they are reformulating all aegeline containing products and they have destroyed all products containing aegeline.

Could it possibly be that the aegeline did cause the acute hepatitis? I'm not saying that aegeline is the culprit or not but this is kind of telling...

In the article it would appear that USPLabs is not even going to bother to fight the FDA on aegeline. Apparently they've informed the FDA that they are reformulating all aegeline containing products and they have destroyed all products containing aegeline.

Could it possibly be that the aegeline did cause the acute hepatitis? I'm not saying that aegeline is the culprit or not but this is kind of telling...

I don't think this compound is going to give anyone hep virus, unless it was somehow contaminated within a few days to a week before being packaged, shipped, and into the hands of the consumer.

I don't think this compound is going to give anyone hep virus, unless it was somehow contaminated within a few days to a week before being packaged, shipped, and into the hands of the consumer.

The acute hepatitis was supposedly non-viral. That's why the suspected the supplements. I personally haven't used the new OEPs but did run a bottle of Versa-1 a long while back and currently still have like 1/4 of a tub left of Enhanced. Making me kind of wary to use Enhanced any further...

I have the intl version. Which is being discontinued. It has something version similar to what you posted above.

You're ok I think (and I hope, for my own sake, lulz). N-(2-hydroxy-2-p-methoxyphenylethyl)benzamide is tembamide and from what I can tell, is different from aegeline. Supposedly from a different plant as well(?). Aegeline is from bael and tembamide is from zanthoxylum f-a-gara(?).

You're ok I think (and I hope, for my own sake, lulz). N-(2-hydroxy-2-p-methoxyphenylethyl)benzamide is tembamide and from what I can tell, is different from aegeline. Supposedly from a different plant as well(?). Aegeline is from bael and tembamide is from zanthoxylum f-a-gara(?).

Looks like it's still good to go here in the US. They did remove Enhanced off the PES US website's homepage though. It's not even a product that is listed on their front page anymore where they have all the products laid out. The product page for Enhanced on the US site also says that it's discontinued.

Interestingly enough though and I don't know if this has any impact on discontinuation of products or not, both tembamide and aegeline shares p-Methoxyoctopamine as a product of hydrolysis. I think p-Methoxyoctopamine might be what the end goal and purpose of using aegeline and tembamide would be.

There's no reason to believe that Aegeline would cause severe hepatitis or death.

It's a significant constituent of Baal Fruit and I wasn't aware that acute debilitating non-vital hepatitis was widespread in India where it is consumed in the diet in probably higher doses than is contained in any of USPLabs supplements regularly.

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Regarding the pesticide hype that has gone around.

Yes, essential oil of aegle marmelos leaves is used as a pesticide.

You would also know if it was in the products because being high in limonene they would smell strongly of citrus, and it is a skin and respiratory irritant.

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USPLabs should have just skipped the aegeline name and the chemical nomenclature on Versa-1 and gone with 'Aegle Marmelos extract' and probablyt nothing would have ever been pointed towards aegline as a cause of this...

so a group of people took ol aegeline in hawaii and got sick; filthy-ass, parasite-ridden hawaii, the same place where tourists go to puke their guts out for 7 days after drinking the water and the FDA points to a supplement? please

Aegeline is not being pulled because people are getting sick and is not the cause, has not been confirmed that it is the cause. The FDA is pulling it because it doesn't comply with DSHEA.

yeah, i was referring to this:"Hawaii officials are investigating 36 illnesses associated with OxyElite Pro, Sarah Park, M.D., State Epidemiologist with the Hawaii State Department of Health, said yesterday in an interview with Natural Products INSIDER. At least two illnesses required liver transplants and officials have reported one death.Although other cases have been reported linking supplements to hepatitis, Park said the decision was made this week not to investigate those other products because officials could not find commonalities. She said 36 cases, or 82 percent of the total illnesses, WERE linked to OxyElite Pro. Park did not name the other supplements that have been linked to hepatitis. " "the FDA is taking the lead role in identifying the relationship between OxyElite Pro and the reported illnesses." "A spokesperson for FDA said the "investigation is ongoing" "Health officials urged consumers to discontinue use of the product."

i saw this interview about a woman who grew sprouts and she was accused. they tested five times and couldnt find contamination, which i guess is insanely difficult to pull off for a little operation like hers. anyway, she was pressured to do a recall anyway (which didnt make sense to her, i guess some bigger corporations wanted her to be the one to go down instead). she cracked under the pressure. later, she said giving in was her biggest regret, as the recall is PUBLICALLY VIEWED as an admission of guilt

36 people contracted non-viral hepatitis with Oxyelite Pro as the common factor and you're saying the country is at fault? Tourists get sick because they arn't used to the water. The comparison makes zero sense.

38 isnt alot of people for an entire area that has filthy, disease-contaminated water. my sister went there and got really sick; oxy elite wasnt involved. conversely, i can drink water anywhere on the globe, as long as it isnt disease-ridden. none of that makes sense to you? areas that have crappy water that tourists arent used to are areas that have disease problems

38 isnt alot of people for an entire area that has filthy, disease-contaminated water. my sister went there and got really sick; oxy elite wasnt involved. conversely, i can drink water anywhere on the globe, as long as it isnt disease-ridden. none of that makes sense to you?

What the heck?

Locals don't get sick most likely due to a form of immunity to it, you get sick because you don't; I have no idea where you are going with this? 36 is alot of people to contract non-viral hepatitis (I think you need to google what this is), especially when all of them consumed Oxyelite pro.

I dont deny your sister got sick, but what has that got to do with non-viral hepatitis?

What the heck? Locals don't get sick most likely due to a form of immunity to it, you get sick because you don't; I have no idea where you are going with this? 36 is alot of people to contract non-viral hepatitis (I think you need to google what this is), especially when all of them consumed Oxyelite pro. I dont deny your sister got sick, but what has that got to do with non-viral hepatitis?

areas with poor hygeine are areas with poor hygeine. they dump toilet water/ drugs all that crap into their water. god knows whats in there. this hasnt been determined, so you could give me more credit than "zero sense" considering the FDA spokesperson said "Meanwhile, Park acknowledged she would like to determine what actually caused the illnesses in Hawaii, but such conclusive findings may be elusive."Sometimes, the best I can do is find the strongest association,"

areas with poor hygeine are areas with poor hygeine. they dump toilet water, drugs all that crap into their water. god knows whats in there

I understand that.

But where are the people who also contracted the same illness who did not consume Oxyelite pro? Surely not all of tourists in Hawaii use Oxyelite pro? if it was the water, then more cases would have occured.

But where are the people who also contracted the same illness who did not consume Oxyelite pro? Surely not all of tourists in Hawaii use Oxyelite pro? if it was the water, then more cases would have occured.

There were cases of it without OEP in Hawaii.

They've said that in almost all the articles, it's just that the majority used OEP (80% or so), they've left the other supps used unnamed for those who didn't use OEP.

Hawaii officials are investigating 36 illnesses associated with OxyElite Pro, Sarah Park, M.D., State Epidemiologist with the Hawaii State Department of Health, said yesterday in an interview with Natural Products INSIDER. At least two illnesses required liver transplants and officials have reported one death.

Although other cases have been reported linking supplements to hepatitis, Park said the decision was made this week not to investigate those other products because officials could not find commonalities. She said 36 cases, or 82 percent of the total illnesses, were linked to OxyElite Pro. Park did not name the other supplements that have been linked to hepatitis.

I understand that. But where are the people who also contracted the same illness who did not consume Oxyelite pro? Surely not all of tourists in Hawaii use Oxyelite pro? if it was the water, then more cases would have occured.

yeah, there's 18% who just plum got it. but then i dont know what to make of this: "USPlabs believes counterfeit versions of OxyElite Pro are being marketed in the United States