The station primarily plays rock, but also some metal. Station promos often included comparisons to other stations, saying that while other stations were playing synthesizer-music, V-Rock was playing rock. Jezz Torrent of Love Fist also makes a couple of appearances, stating that "You're listening to V-Rock". The station's mascot was a vulture, as seen in the station's logo, and Lazlow often complained that it got more air time than he did. The V-Rock Hotel in Las Venturas, San Andreas was named after the station and featured its logo in its sign. Kent Paul often hung out with Love Fist at V-Rock's Vice City headquarters, and gave Tommy Vercetti several missions from there. Two songs by Love Fist appear in the playlist as well. It also has a phone line, slightly similar to that of Chatterbox. The three callers featured are Couzin Ed, Mitch Baker and a person who refers to himself as Snow-Dog.

Trivia

Due to copyright issues, the song, Looks That Kill, was excluded from the European release of the game.

In Vice City Stories, Couzin Ed says "turn up the radio, it's Autograph" right before playing All I'm Gonna Take. This is a reference to the song Turn Up The Radio by Autograph in GTA Vice City.

Couzin Ed also says "Comin' atcha live! The bitch is back...", referencing to Cumin Atcha Live by Tesla in GTA Vice City, The Bitch Is Back by Elton John is also a popular classic rock song, although, not on the playlist.