Friday, December 28, 2012

Imagine being diagnosed with cancer, a genetic disease, or even age-related deterioration in the morning, given a single injection in the evening, and beginning your recovery the next day. No prescriptions, no lengthy treatments, no difficult decisions between finances and getting better. This is the promise of gene therapy, a promise already being fulfilled.

Image: One method of gene therapy - taking human cells, "editing" them genetically, and reinserting them into the human body where they will replicate and carry out their newly designed functions. (Microsoft Encarta Online Concise Encyclopedia)

Gene therapy is the identifying of faulty genes, be they inherent or mutations in the form of cancer or aging, and designing a vector to replace the faulty genes with fully functional, repaired versions of your genetic code. Once introduced, the corrected genes replicate themselves, displacing aged, mutated, or faulty versions. The technology is a double-edged sword however - and can be used to harm just as well as help - in very profound ways. Public awareness and engagement in the emerging field of genetics is an absolute necessity to ensure this technology is used for good rather than profit, or worse yet, increasing death and disparity.

A Promising Sword Still in the Hands of a Dangerous Enemy

The prospect of using the concepts behind gene therapy for genospecific weapons was mentioned in the Neo-Conservative Project for a New American Century's (PNAC) 2000 report titled, "Rebuilding America's Defenses" (.pdf) which stated:

The proliferation of ballistic and cruise missiles and long-range unmanned aerial vehicles (UAVs) will make it much easier to project military power around the globe. Munitions themselves will become increasingly accurate, while new methods of attack – electronic, 'non-lethal,' biological – will be more widely available. (p.71 of .pdf)

Although it may take several decade for the process of transformation to unfold, in time, the art of warfare on air, land, and sea will be vastly different than it is today, and 'combat' likely will take place in new dimensions: in space, 'cyber-space,' and perhaps the world of microbes. (p.72 of .pdf)

And advanced forms of biological warfare that can 'target' specific genotypes may transform biological warfare from the realm of terror to a politically useful tool. (p.72 of .pdf)

This September, 2000 document would also state (emphasis added) :

A transformation strategy that solely pursued capabilities for projecting force from the United States, for example, and sacrificed forward basing and presence, would be at odds with larger American policy goals and would trouble American allies. Further, the process of transformation, even if it brings revolutionary change, is likely to be a long one, absent some catastrophic and catalyzing event – like a new Pearl Harbor. (p.63 of .pdf)

Exactly one year later, the US would "serendipitously" experience "a new Pearl Harbor," described as such by the very signatories of this report. This "catastrophic and catalyzing," not to mention convenient, event was the September 11, 2001 attacks on the World Trade Center in New York City and the Pentagon in Washington D.C. The "transformations" described by the 2000 PNAC document would then unfold in quick succession, including elements described under "cyber-space" warfare now demonstrably unfolding against nations like Iran.

Likewise, ideological partners of PNAC at the American Enterprise Institute (AEI), namely Jon Entine, constitute modern-day Nazi eugenicists, who have literally penned articles advocating a renaissance of the disgraced inherently racist pseudo-scientific discipline, while laying the groundwork for legitimizing genospecific policies - including in warfare.

When it is time to present genospecific weapons to the public, it will be those like Entine at the AEI crafting the talking points.

Entine is also a tireless supporter of genetically modified organisms (GMO), more specifically the poisoned, dangerous products of big-agri giants like Monsanto and Syngenta. His website, the "Genetic Literacy Project" is a shameless clearing house for big-agri lobbying efforts - funded by big-agri. His ties to corporate-subsidized academia and corporate special interests indicates that his intentions to abuse this technology are not merely the rants of a single man, but an institutionalized agenda he serves as a spokesman for.

People like Entine thrive because of the vast and profound public ignorance surrounding genetics in general, as well as topics including genetic engineering, gene therapy, and the threats and opportunities each represents. A real genetic literacy project, run by local DIYbio community labs (video), with hands-on projects and workshops, would go a long way in combating big-agri's reality skewing "Genetic Literacy Project." Tying these local groups with nearby institutions not only helps keep those on an institutional level honest, but also working in the best interests of the majority, with communities supporting them.

When lies are told by the likes of Entine and other paid-for faux-academics, a well-armed population will be immediately aware of it. With a network of increasingly better equipped community labs, people will have the means of holding accountable corporate-giants, and combating their encroachments upon their communities in terms of agriculture and health care. In the light of truth, people like Entine and those he represents cannot operate with the impunity they now enjoy.

Image: Glybera - the first Western-approved gene therapy may treat a rare genetic disorder affecting the pancreas for an entire lifetime with a single treatment. One doesn't need to stretch their imagination far to imagine the consequences this will have on big-pharma profiteering, nor the measures they will take to protect their interests. Ultimately, such treatments belong in the people's hands - not special interests and the governments that serve them.

Another threat exists, coupled with the very promise of gene therapy. In November of 2012, the first gene therapy to get Western approval made news. Called Glybera, developed by Amsterdam-based UniQure, it treats a rare genetic condition that effects the pancreas. Glybera may be effective over the course of an entire lifetime, meaning it is a one-time treatment. Jörn Aldag, CEO of UniQure, proposed a question, "how do you price a one-off treatment?"

In reality, disease is like a war. A nation would not "price" the survival of their nation in the face of a looming enemy, nor should they "price" the survival of their population in the face of disease. Of all the things a nation should throw public money at, an institution of health producing permanent cures for disease and age related deterioration should be at the top of the list. Unsustainable national health care schemes consuming billions of dollars a year, in need of rationing care, as well as compromising on quality, would be transformed by such an initiative. Special interests would be the only ones to lose out, and because special interests currently drive human destiny, this is precisely why such a transformation is not on the drawing board, or part of public discourse.

Again, public ignorance provides the shadows within which this racket is allowed to continue. While Glybera is the first gene therapy to be approved, treating a very rare genetic condition, many other treatments are being tested - including cures for hemophilia and even blood cancers. Such revolutionary work should be at the center of public health news and debate - as well as how to direct more resources into this research considering the profound long-term benefits it will have on every single member of society. Expanding the human resources necessary to research and develop a new health care paradigm should also be at the center of public health debate. However, it is not.

Instead, policy issues such as health insurance, government subsidies, and rationing are the political footballs of choice used to distract the public from real paradigm-shifting issues. Such policies not only preserve the current big-pharma profiteering rackets, but help expand them in stride with financial frauds across the multinational insurance "industry."

Disarming the Enemy

The answer is not to wait for politicians and the corporate-media to address these topics and hold the discourse required - as both are partnered with the very corporate-financier interests perpetuating this false paradigm. Instead, the people must take matters into their own hands, decentralizing both the debate on health care as well as tackling health care issues themselves.

The first step is educating ourselves and the public of both the promises and the current realities of the expanding field of genetics and bioengineering. With the Internet and free university open courseware lectures, anyone can take a crash course (MIT OCW - video) on the basics of genetics and bioengineering.

With a table, a sink, and basic kitchen equipment, local groups already meeting in the context of hackerspaces or makerspaces, can begin exploring and educating others about biology and genetics. Inviting professionals to oversee more complex experiments, classes, and demonstrations, as well as manage safety and provide educational opportunities for the public can be a next step. Many university competitions involve bioengineering. Teams require a space to meet and conduct research, to design and test experiments. A community initiative to provide students with a permanent place to do this can lead to a community lab - opening the door to a larger collective community of DIYbio enthusiasts.

Video: Genspace is a community lab located in New York City. It provides a model for other communities to follow - one that is both responsible and holds immense implications as people begin to engage at a grassroots level in driving science and technology. While many worry about such technology in the hands of ordinary people, DIYbio will most likely take the form of the Internet - where trouble makers are vastly outnumbered, and their disruptions easily managed by an increasingly informed and capable tech community.

Just as 3D printers and other forms of increasingly affordable and capable manufacturing equipment are finding their way into local spaces created by various community initiatives, biomedical technology will likewise become more affordable and easier to use by a greater number of people. It is important to have the local human resources and infrastructure to support leveraging this technology for the best interests of the people - not only institutions and corporations.

Educating ourselves, others, as well as creating a community space for developing and deploying biotechnology may seem like a small step to take. But communities across America, and around the world doing this in parallel will have a profound impact on both the health care debate, as well as health care itself. It will encourage a well informed air of transparency around this currently misunderstood and monopolized discipline.

Large pharmaceutical corporations and even IT corporations like IBM and Google seeking to skew the course of public health care, will no longer be able to hide in the shadows of public ignorance and perpetuate an unsustainable, inhumane, profiteering approach to human health care. Everyone deserves the absolute best health care possible - and that can only be done through technological innovation built upon a solid foundation of education within a well informed, productive and engaged society. Current policy seems designed to accomplish the exact opposite, to leave society ignorant, blind, and at the whims of an increasingly unstable ruling elite.

There is an army of people like Jon Entine, bent in service to special interests who have documented their intent on monopolizing and abusing bioengineering as a means of profit and literally as a weapon of war. Unlike bullets, genospecific weapons have the capability of permanently and profoundly changing the very nature of what it means to be human. Those monopolizing such weaponry have the ability to either wipe us out entirely, or transform us into something entirely inhuman - subservient - or as Bertrand Russell put it:

Gradually, by selective breeding, the congenital differences between rulers and ruled will increase until they become almost different species. A revolt of the plebs would become as unthinkable as an organized insurrection of sheep against the practice of eating mutton. - The Impact of Science on Society (.pdf) by Bertrand Russell, page 51 (page 29 of .pdf)

In Russell's time, genetic engineering - instant selective breeding - was not a possibility, but what Russell's quote indicates is that the motivation exists amongst the ruling elite to achieve such disparity. Now they have the tools to achieve it within a single lifetime. We have the ability to break this monopoly, and replace disparity with a full spectrum balance of power by localizing civilization's infrastructure from the mundane, to the cutting edge of technology.

Reclaiming human progress, technology, and innovation through localization is perhaps the most important battle of our time, one that will leave the victor on top, forever.

11 comments:

Anonymous
said...

Thank you Tony for offering a well balanced and positive breakdown of this delicate topic. I've always thought something was wrong with those who say that this type of experimentation is inherently wrong. As you have highlighted here, technology is neutral ... we just can't permit only the psychopaths to have it. It is in our very fabric to be creators and problem solvers. Time to create and get solving.

There is some evidence that targeting a "genotype" was first used (genospecific weapons) on the Gays who expressed that particular gay gene. (As we now know, both nurture and nature are involved in being "Gay". One or the other or both.) This gene targeting killed those who expressed the gay gene by AID$. They were for all intent and purposes the experiments and the first martyrs killed. Or at least that's what I've been saying for the past 25 years. Now it's becoming a probable evidential theory.

"Glybera - the first Western-approved gene therapy may treat a rare genetic disorder affecting the pancreas for an entire lifetime with a single treatment. One doesn't need to stretch their imagination far to imagine the consequences this will have on big-pharma profiteering...."

Following the bouncing ball, trying to find out who or what owns Glybera, it looks like lots of new holding companies, shell companies and secret investors. Follow the money surely applies to all of this??????

The company providing the money is Forbion Capital Partners. They appear eager to get into bed with any big pharma company and do business with dozens of them.Amsterdam Molecular Theraputics (AMT) the developer of glybera, was very secretive about its investors, and was bought by uniQure BV, backed by Forbion money.Typical.

Although I see no other path, I can't help but think that, until we solve for sociopathy and psychopathy, there will continue to exist among us those who would use these technologies to attain power, at the expense of the good of mankind both individually and as a whole. Given such technologies, the next Stalin, Mao, Hitler, Pol Pot, Amin, Vlad, Nero, or Napoleon will have no compunction about using it against whomever they decide threatens their interests.

We see our world now in a state in which the Haves have decided there is a glut of Have Nots on the surface of the Earth, a surplus of unnecessary humanity (I believe one of them coined the phrase "useless eaters"). Unless we can identify, isolate, and contain these types, bio-warfare against humanity will increasingly be their weapon of choice against us. And they will use it, while claiming amongst themselves that they are doing this for the long term survival of the human race (meaning themselves and their kind).

Cusp of ending big pharma - how stupid. And gene therapy - even more stupid. Gene therapy is based on the self serving notion that genes cause disease - and that is patently false. Gene therapy advocates would have us believe that while for all other creatures, genes adapt to their environment, for humans genes are a source of disease - obvious rubbish logic. The Free Radical Theory of Cancer explains a lot about genes and their role in disease - so much so and so logically that this theory is now pretty much ignored - its implications are just too horrendous, to the patent based medical industry that is. The truth has been known a very long time; about 2500 years ago Hippocrates – the father of medicine – stated, “Let your food be your medicine, and let your medicine be your food.” It was true back then and is still true today.

Abinico - who said genes cause disease? Do you know what a gene even is? It is a blueprint your body uses to carry out functions. These blueprints can be wrong from birth, or mutated overtime by errors in replication or environmental factors.

Gene therapy simply corrects these mutations, bringing your genetic code back to an optimal state from which your body can carry on. You still need to exercise, you still need to eat well, you still need to take care of your health.

The article suggests you should get educated about genetics ... perhaps you should take that advice.

Don't condemn genetics because you don't understand it and don't have the time or capacity to study it.

This is the problem with Capitalism, and the monetary system in general. Everything relates to someone getting rich, at the expense of someone else. Money is a human invention; and is not a permanent thing.Tony mentioned in this article that "Everyone deserves the absolute best health care possible - and that can only be done through technological innovation built upon a solid foundation of education within a well informed, productive and engaged society." This touches on what many have called 'the scientific world view'. That is, we find out what best improves human life and supports the environment that we live in. Then we DO IT.The only way this can be achieved is if we abandon money. Money is a way to facilitate our need to 'own' things. We 'own' things only because they are perceived as being scarce. Technology can eliminate all scarcity. If you'd like to know more, research the term 'resource based economy'.

The human Genome project found there were not enough genetic sequences to map the supposed one gene defines one section of the human system. This one to one mapping was a basic assumption of genetic theory. There has been no correction genetic theory to take this into account. Therefore any any work based on this genetic theory is flawed.

Also epigenetics implies that environment effects the genome, so making assumptions that playing with the genome will fix a disease appears to be making rather large assumptions about how life works, rather than dealing with the whole situation.

Also the above assumes that genetic theory is the full understanding of how a human works. The quantumn biological level of a human being is only just starting to be understood. This may completely change how we view healing.

So from my point of view the above article is missing some rather fundamental scientific understanding. So go ahead if you believe this to be a set of miracle cures, but I for one will not be taking them, as I consider it to be flawed science and rather dangerous

I don't doubt that gays were targeted for AIDS, that may well have been the case. There is, however, NO GAY GENE - never has been. I'm married to a biologist/geneticist and he's studied the whole AIDS thing; when it first came out, he worked for PA state as a microbiologist and got all the reports firsthand. He's also studied the whole gay thing from all angles. There has never been any "gay gene" discovered and he worked with a Nobel prize-winning geneticist. I think he'd know. Any other geneticist will also say the same thing.

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