Dollars at Work

Introducing Terry Fox Research Institute’s PROFYLE: A Canadian led group of the top minds in pediatric cancer

Although overall survival for children with cancer has improved substaintially over the last three decades, significant challenges remain. A considerable number of childhood cancers are incurable, with a very high mortality rate approaching 80-90%. This mortality rate has not improved despite advances in imaging, surgery, chemotherapy and radiation treatments over the past few decades.

The solution

The overall goal of the PROFYLE program is to support next generation sequencing of DNA obtained from tumours and blood from these children to identify genes, proteins and signalling pathways towards real time personalized therapies for at-risk children.

Alberta focus

On an annual basis, 150-200 children across Alberta are diagnosed with cancer; 20-30 of these children with cancer will relapse or progress and will be eligible for the PROFYLE program. An equal number of adolescents and young adults will be similarly diagnosed and relapse/progress. Thanks to you, these children, adolescents and young adults will benefit from access to this world-class PROFYLE program, giving them personalized treatment options that will be translated into new therapies for many other children. Thanks to you, they will have hope.

Thanks to the World's Longest Hockey Game for making life better for children in Alberta facing cancer.

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