This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

Alternative names

70Z-SHP

EC 3.1.3.48

HCP

HCPH

Hematopoietic cell phosphatase

Hematopoietic cell protein tyrosine phosphatase

Hematopoietic cell protein-tyrosine phosphatase

HPTP1C

Protein tyrosine phosphatase 1C

Protein tyrosine phosphatase non receptor type 6

Protein tyrosine phosphatase SHP1

Protein-tyrosine phosphatase 1C

protein-tyrosine phosphatase SHP 1

Protein-tyrosine phosphatase SHP-1

PTN6_HUMAN

PTP 1C

PTP-1C

PTP1C

Ptpn6

SH PTP 1

SH PTP1

SH-PTP1

SHP 1

SHP 1L

SHP1

SHP1L

tyrosine protein phosphatase non receptor type 6

Tyrosine-protein phosphatase non-receptor type 6

see all

FunctionPlays a key role in hematopoiesis. This PTPase activity may directly link growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation.