1) High ISO stinks. You want as low of ISO as possible. But that means you need more light.

2) Larger Aperture gives you more light. However, it also gives you less depth of field. Which means on a landscape your foreground or background may look kind of fuzzy.

3) Smaller aperture boosts your depth of field. BUT, it requires more light. Furthermore, at small apertures you start running into Diffraction limitations which can make your image look fuzzy.

4) Slower shutter speeds can make pics look fuzzy due to Camera Shake, and movement of stuff like leaves, grass, etc.

In general your choices are:

a) Shoot at a higher aperture and use a Focus Stacking technique to ensure eerything in focus. focus on something a bit closer (10 feet or so), and then something far off to get 2 pictures and stack em to maximize focus.

b) Shoot at F8 but on a tripod. This way you can have slow shutter speed and smaller aperture but lowest ISO and no shutter shake. Take multiple shots so you can get 1 without wind blowing leaves or whatever.