As for being 43, she says she thinks it's "important" to mark every birthday.

She also reflected on rumors she's pregnant and people who question how happy she can be since she has no children. Aniston was blunt, calling them "narrow-minded," adding, "That doesn't measure the level of my happiness or my success in my life, or my achievements, and any of that. It's just truly being comfortable, and not giving a crap about what other other people think."

But she says she does care about what people she cares about think of her.

Aniston admitted getting "very nostalgic" about "Friends," even watching reruns now and then. She says she doesn't remember some episodes, so it's as if she's seeing them for the first time.

To see the entire interview, click on the video in the player above. And to see a Web exclusive in which she talks about her new dog, click on the video below: