Wedelolactone Specification

The CAS register number of Wedelolactone is 524-12-9. It also can be called as 6H-Benzofuro(3,2-c)(1)benzopyran-6-one, 1,8,9-trihydroxy-3-methoxy- and the IUPAC name about this chemical is 1,8,9-trihydroxy-3-methoxy-[1]benzofuro[3,2-c]chromen-6-one. The molecular formula about this chemical is C16H10O7 and the molecular weight is 314.25. This chemical is a antihepatotoxic coumestan from Eclipta prostrata and Wedelia calendulacea (both Asteraceae).

Preparation: this chemical can be prepared by 1,8,9-tris-benzyloxy-3-methoxy-benzo[4,5]furo[3,2-c]chromen-6-one. This reaction will need reagent hydrogen, catalyst Pd(C) and solvent dioxane. The objective of this reaction is product distribution. This reaction also needs 2nd step of purification of 9 (wedelolactone). The yield is about 82%.

When you are using this chemical, please be cautious about it as the following: This chemical is harmful if swallowed and it may cause sensitization by skin contact. When you are using it, wear suitable protective clothing and gloves.