The CyberCell database (CCDB) is a comprehensive collection of detailed enzymatic, biological, chemical, genetic, and molecular biological
data about E. coli (strain K12, MG1655). It is intended to provide sufficient information and querying capacity for biologists and
computer scientists to use computers or detailed mathematical models to simulate all or part of a bacterial cell at a nanoscopic
(10-9 m), mesoscopic (10-8 m) and microscopic (10-6 m) level.

The CCDB may be accessed by clicking on any of the hyperlinked buttons located at the top of this page.
The CCDB database is actually several databases, one
(CCDB)
contains quantitative proteomic, genomic and metabolic information about E. coli. The
CC3D
database contains 3D structural data for E. coli structural proteomics work, the
CCRD
database contains detailed information on E. coli RNA molecules while the CCMD
database contains quantitative information on E. coli metabolites. Each database is presented as a re-formattable
synoptic table which allows users to casually browse the databases. Detailed information about each gene, protein,
RNA, structure or metabolite may be obtained by clicking on the "*Card" button on the left column. Each card
contains more than 60 fields concerning all aspects of the sequence, function or structure of a given molecule.
CCDB users may also perform text searches (using the Search button),
BLAST sequence searches (using the BLAST button)
or conduct more detailed data extraction or relational data searches (using the
Extract button).
Statistical information and general information about E. coli are accessibile by clicking on the
Statistics and
About E.coli buttons. Flatfile versions of
the CCDB entries, and useful pre-compiled lists of protein data can be found on the
Download
page. A complete listing of all of the electronic databases and programs used to
construct and update CCDB can be found on the database
summary page.

By its very nature the CCDB is continually evolving and will not be "complete" until
sufficient data has been collected to perform all levels of the desired cellular simulations. CCDB is an integral part of Project CyberCell*,
a large-scale multi-lab project based out the University of Alberta. The CCDB functions as an archival bioinformatics resource for Project
CyberCell serving as a warehouse of prior or existing knowledge as well as a repository for newly acquired, experimental knowledge about
E. coli. The CCDB is intended to be a community project and as such it provides facilities for E. coli researchers world-wide to submit,
correct or add data to the database. Submissions, additions, corrections and comments are welcome.

* Project CyberCell is also part of the International E. coli Alliance, an multi-national project aimed at coordinating E. coli simulation
and E. coli bioinformatics efforts across Canada (Project CyberCell), the US
(EMC2), Japan (E-Cell) and the European Community
(SiliconCell, GSK)