This is meant to be a non-scary SCP, with the instances being contained mainly due to their anomalous physiology, thus violating normality. It's also an SCP dealing with a folkloric being (cynocephali), which is something I'd like to see more of hereon. Also made it as a challenge to myself, trying to write a short skip, as opposed to my last article (SCP-2815).

I'd say the tone in this one is 'baffling,' rather than being horrific or particularly comedic. It's a very basic idea, treated as universal and incredibly mundane. I think the text's insistence that it's really wide-spread and the detailed elimination of the possibilities, mostly coming up with nothing, ends up working for me.

It might be too basic for others, so I recommend getting more feedback if possible.

On to specifics.

They are to be provided the same amenities as regular human subjects. Additionally they are to be provided with: (1) canine toothbrush; (3) packs of disposable straws, weekly; (1) table fan; (3) platters, daily, to go with each meal and retrieved by staff, (2) feeding bottles; (1) handheld vacuum cleaner; (1) pack of vacuum bags. These items are intended to facilitate daily life for captive instances, as necessitated due to their altered physiology.

I like how this serves to illustrate the mundanity of daily life for these people, but it's getting into the weeds. Like, why the table fan and dustbuster? It would be good to shorten the list to only the most interesting or sensible items.

All instances shall be assigned a personal staff contact, who will act as caretaker and researcher of their assigned specimen and who must possess Level 3 clearance and be skilled in the use of self-defence techniques.

This seems entirely unnecessary and a waste of resources. Level 3 are, like, Senior Researchers, and there's nothing in this entire article suggesting that these things need karate-trained personal caretakers and guardians.

Captive instances are allowed access to lounge and recreation areas for humanoid SCPs between 14:00 and 19:00 GMT, under armed escort.

Weird bit of world-building, but ok. Is this communal?

Any and all privileges enjoyed by a captive instance of SCP-XXXX-1 may be revoked as a disciplinary measure by request of assigned Level 3 personnel, following approval of Level 4 staff. The use of key-locked muzzles as punishment of violent instances is authorized.

Again, probably unnecessary, or at the very least too detailed.

Exposed civilians are to receive either Class A or B amnestics. Civilians with long-term memories of SCP-XXXX-1 who have been responsible for containment pre-discovery must be either co-opted into containment procedures or relocated to a Foundation internment facility for non-anomalous humans. Such civilians may be allowed onsite as visitors pending approval from Site Director and assigned Level 3 personnel.

Good lord, that's depressing. I don't see the point of providing this information at all, even if you want to do that world-building, since this paragraph would basically apply to any SCP.

Further note on containment procedures, is there any way for the Foundation to confirm that these people are or are not instances of -xxxx, as opposed to some other anomaly? Maybe DNA test the head and body? I mean, you don't just want to throw every dog-headed humanoid in a low-security facility.

of which 84 have been confirmed terminated(Mostly by the Global Occult Coalition.)

That's not a technical term. I would make classical lowercase, or use lowercase ordinary or typical.

SCP-XXXX is not contagious and no pathogen has been identified, suggesting thaumaturgy as the most likely cause.

It does not suggest that. Other things you've mentioned suggest that, but absence of evidence for some causes is not positive evidence for others. It's an anomaly, it could be anything.

In all documented cases, instances have preferred remote locations far away from population centres.

Maybe change to "sought out" or "moved to" such locations. "Preferred" doesn't really imply action, and fits better in the next sentence anyway.

and SCP-2481-3. If a relationship to the latter can be proven, it will confirm our hypothesis that SCP-XXXX is the result of postnatal thaumaturgic alteration.

The link here is tenuous at best. 2481-3 is related to a very specific cause and has alterations much unlike xxxx, and doesn't even seem to be based on a real animal, so it really doesn't make the end note any more convincing.

If you wanted to say that there was some thaumaturgic research linking xxxx to 2481-3, that would be more convincingly related, but that would probably be too complex and I'm not sure how much it would add. It would make more direct sense for the Foundation to be negotiating with the Catholic or Orthodox church for St Christopher's relics (I'm not sure who has them), but honestly the following paragraph would work just fine without either.