Background and Design: Skin diseases are among the most prevalent problems in medical practice. Dermatologists have become active, not only in treatment of skin diseases, but also for the cosmetic and surgical procedures. The purpose of this study was to evaluate the profiles of patients visiting outpatient dermatology clinic of ...

"Targeted phototherapy" is a recently described therapeutic option in photodermatology. It is used to describe the phototherapy devices which can deliver high doses of ultraviolet (UV) radiation selectively to the involved skin. Several of these devices with different emission spectrums are currently in use. 308 nm monochromatic excimer light (MEL) ...

Recent attention to the monoamine oxidase inhibiting properties of Banisteriopsis caapi's harmala alkaloids has precluded a balanced assessment of B. caapi's overall significance to indigenous South American societies. Relatively little attention has been paid to the cultural contexts, local meanings and patterns of use of B. caapi among snuff-using societies, ...

UN reports point to a steady increase in heroin use in a number of African countries, including South Africa. South Africa also has one of the highest HIV infection prevalence rates in the world. Given the link between intravenous heroin use and HIV transmission, this study aimed to investigate HIV-related ...

Drugs are a frequent subject in the news media. Despite the existence of an important dynamic interplay between the print media, public opinion, and public policies, studies on these relationships are still scarce regarding the drug issue. The objective of this study is to understand the newsmaking process regarding drugs ...

The purposes of this study are to (1) examine the extent to which young adult Ecstasy users recently reported having had multiple sex partners and (2) identify the factors predictive of engaging in this behavior. Potential predictors included demographic characteristics, background and experiences measures, childhood maltreatment experiences, substance use variables, ...

The phenomenology of drug craving has become the focus of much research within addictive disorders because of the belief that desire plays a role in maintaining the addiction. Many of the studies have focused on the activation of neural pathways, particularly within the dopamine system in response to specific events ...

A hypothetical link between marijuana smoking and cancer has been established based on a number of misleading assumptions. However, recent studies tend to suggest, if anything, an inverse association between marijuana use and cancers. To test the hypothesis that marijuana smoking significantly lowers the risk of developing cancer in humans, ...

The purpose of this study was to investigate the safety of different doses of MDMA-assisted psychotherapy administered in a psychotherapeutic setting to women with chronic PTSD secondary to a sexual assault, and also to obtain preliminary data regarding efficacy. Although this study was originally planned to include 29 subjects, political ...

Substance use is common among young people and can escalate into significant problems for affected individuals and their families. Family responses can influence the course of youth substance use and its consequences for family members, including parents and siblings. Family-level interventions developed to date have neglected the important role that ...

The purpose of the current study was to assess the rate of substance use in patients with medical diseases who were admitted to different wards at Shiraz hospitals affiliated to the Shiraz University of Medical Sciences. Data were gathered from 600 randomly selected patients by a structured interview that included ...

Systemic lupus erythematosus (SLE) is a connective tissue disease characterized by vasculitis, which may involve multiple organs as well as the skin. Serologic tests for syphilis may be false positive in SLE. Although the false positivity of VDRL (Venereal Disease Research Laboratory) is commonly seen, false positivity of TPHA (Treponema ...

Acute infantile hemorrhagic edema (AIHE) is considered to be an uncommon form of cutaneous vasculitis, occurring in children under two years of age. It is characterized by fever, purpuric ecchymotic lesions located symmetrically on the face and extremities, and subcutaneous inflammatory edema. Infections, drugs and immunization have been considered as ...

Vitamin D was originally discovered as a factor that regulates calcium and bone metabolism. Recent advances in investigation have shown that vitamin D also functions as a regulator of cellular growth and differentiation in various tissues. Evidence has accumulated showing that the active form of vitamin D and its analogs ...

Objective: Mastocytosis is a disease characterized by abnormal growth and accumulation of mast cells in one or more organ systems. The skin is the most commonly affected organ. It is aimed to present demographic, clinical and histopathological findings of pediatric patients with cutaneous mastocytosis and a review of the literature ...

Objective: Seborrheic keratosis is a benign epidermal tumour that is generally pigmented and develop from the proliferation of epidermal keratinocytes. In this study, two different techniques, spray or probe applications used cryotherapy during the treatment of seborrheic keratosis were compared in terms of efficiency and undesired effects. By this way, ...

Toxic epidermal necrolysis (TEN) is a clinical entity which has a 30 to 40 % mortality rate, with necrolysis affecting the entire epidermis. Antibiotics, nonsteroidal anti-inflammatory drugs and anticonvulsants are offender drugs in TEN etiology. A standard treatment protocol with proven efficacy is still lacking. In this study, current treatment ...

Aim: Acute gastroenteritis is an important cause of hospital
admissions during childhood. The aim of the study was to determine the
incidence of rotavirus gastroenteritis in patients admitted to our
pediatric emergency department.

Aim: Acute viral hepatitis A (HA) and B (HB) are currently widespread health problems in developing countries, where poor hygienic conditions are prevalent. Extrahepatic abnormalities which involve many organs and systems can accompany these infections. Therefore we wanted to determine the rate of hematological complications in our cases diagnosed as ...

Purpura Fulminans is a rare but devastating disease. The acute
infectious type is the commonly encountered form of the disease and is
responsible for about 90% of the cases. The most common etiologic
factors are Neisseria Menengitidis and [beta] hemolytic Streptococcus
among bacterial agents, and Varicella Zoster among viral infections.

Ticks are blood-sucking ectoparasites that act as vectors for rickettsial, spirochetal, bacterial and parasitic infections. Tick-borne diseases continue to cause severe illness and death in otherwise healthy adults and children. Early signs and symptoms of these illnesses often mimic a benign or nonspecific viral illness, making diagnosis difficult. This difficult ...

Rabies, a fatal viral zoonotic infectious disease, persists in both developed and developing countries worldwide in spite of successful preventive public health measures and postexposure therapies. Each year, an estimated 55.000 people die of rabies in Africa and Asia where infection is endemic in dogs. The World Health Organization (WHO) ...

Aim: Varisella-zoster virus infection is one of the most important causes of mortality and morbidity in patients with malignancy. Although there are research studies which aim to decrease complications by vaccination and antiviral prophylaxis, mortality rate is still high. In this study, we aimed to investigate the clinical course and ...

Aim: The aim of this study was to determine the incidence of
nosocomial infections, to analyze the risk factors associated with
mortality of the patients with Stenotrophomonas maltophilia infections
and to evaluate the episodes of S. maltophilia nosocomial infections in
pediatric patients.

Vaccine adverse effects, although more rare and less severe than the disease itself, cannot be totally eliminated. The occurrence of a specific condition after an immunization does not prove that the vaccine was the cause. A true causal association may be propounded only in conjunction with other reports. Thus, a ...

Vaccines, although safe, may be associated with adverse events ranging in severity from mild to life threatening. Vaccine-related adverse events, however, are uncommon and typically mild. Vaccine components can cause local or systemic reactions, including anaphylaxis and urticaria, in some recipients. Some adverse events occur coincidentally in temporal association with ...

Vaccination schedules are designed for healthy individuals under normal life conditions. Some special situations, however, place individuals at greater risk of becoming ill or presenting with adverse post-vaccine events, and may require specific vaccines or vaccine schemes, or even indicate postponement or contraindication of vaccination. Here, some special situations in ...

In the past, many contraindications to vaccination were based on theoretical concerns. These concerns often assumed an immunoallergic mechanism for adverse reactions, whereas many such events are often due to other causes. Other contraindications were based on evidence of excess risk. Therefore, contraindications often varied between countries and over time. ...

The cold chain system refers to the process used to maintain optimal conditions during transport and storage handling of vaccines, starting at the manufacturer and ending with the administration of the vaccine to the person being immunized. Maintaining correct temperatures during storage and handling of vaccines is a major task ...

Immunization against infectious diseases is considered to be one of the most cost-effective public health interventions. Mucosal immunization may be defined as introducing a vaccine by the mucosal route in order to induce both mucosal and systemic immunity against a pathogen. Mucosal immune system is an integrated cross-communication pathway consisting ...

Vaccine-preventable diseases although one of the most important
achievement, continue to be a significant cause of morbidity and
premature death. In this review In this supplement, we would like to
review general recommendations and some suggestion for problem that
could be seen during the routine immunization practice