The San Diego Holiday Inn Express Hotel in Otay Mesa welcomes you!

This choice San Diego hotel is nestled in the heart of the Otay Mesa Industrial Business Park, a short drive from downtown San Diego and less than a mile from beautiful Tijuana, Mexico.

Our new hotel in San Diego offers a convenient suburban location near the Sleep Train Wireless Amphitheatre, SeaWorld Aquatica, SeaWorld, the Chula Vista Olympic Training Park and the famous San Diego Zoo. Your family can learn
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The San Diego Holiday Inn Express Hotel in Otay Mesa welcomes you!

This choice San Diego hotel is nestled in the heart of the Otay Mesa Industrial Business Park, a short drive from downtown San Diego and less than a mile from beautiful Tijuana, Mexico.

Our new hotel in San Diego offers a convenient suburban location near the Sleep Train Wireless Amphitheatre, SeaWorld Aquatica, SeaWorld, the Chula Vista Olympic Training Park and the famous San Diego Zoo. Your family can learn about local history at the Cabrillo National Monument, the Air and Space Museum and the Maritime Museum. For some great bargains, check out Las Americas Premium Outlets with 125 outlet stores and 13 restaurants in a lovely outdoor setting, or try the Otay Town Center Mall, just four miles from our San Diego hotel.

Business travelers will enjoy a stay at our San Diego hotel because of its convenient location near companies such as Toyota, Bose, Panasonic, Maxwell, Tyco, JVC, Siemens Medical and Samsung, each within six miles of our San Diego hotel in the Otay Mesa Industrial Park. The International Commercial Border Crossing is .25 miles away. The Brown Field Municipal Airport is three miles away.

Guest Reviews

Rated 4.3 out of 5 by 109
reviewers.

Rated 5.0 out of 5.0 by Oompa52 On the Border
This hotel is located in the business complex and right next to the Mexican border crossing. Felt plenty safe though the area is quite dark at night. We were not able to find a good place to eat close by so settled for Carl's JR. Better choices are back around I-5.
February 25, 2015

Rated 5.0 out of 5.0 by Betweenclouds Great Service
After a long flight into San Diego, the hotel was better than I was expecting. the staff were wonderful and offer places to visit on our stay. rooms were clean and breakfast in the morning was great
February 16, 2015

Rated 5.0 out of 5.0 by PJ2222 Great Service
Great staff, very friendly!! The gentleman at the front desk that checked us in was quick and efficient. He also gave us some great advice on a fun day trip to Tijuana. He said Tijuana would be very safe and it was. The rooms were clean and quiet. The breakfast was good as well.
February 12, 2015

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