Brett Myers, Astros (vs. CHC, SD): Myers holds a sub-3.00 lifetime ERA against both Chicago and San Diego. His ERA and K/9 rate stand at 2.21 and 9.2 against the Cubs and 2.84/6.1 against the Padres. Myers has also been fantastic in Minute Maid Park with a 2.31 ERA and 1.21 WHIP.

Kyle McClellan, Cardinals (@ARI, @LAD): McClellan put together a great spring to win the rotation spot left by Adam Wainwright. He followed that up with a nice seven-strikeout performance against Pittsburgh in his first career start. Even if he doesn't continue to rack up the strikeouts, his solid groundball rate will keep the run totals low.

Brian Duensing, Twins (vs. KC, @TB):Duensing has owned Kansas City in the past and hasn't been too shabby against Tampa Bay either. Last season he was 3-0 in seven appearances (two starts) against the Royals with a 2.33 ERA. In 19 2/3 innings pitched, Duensing had a 6.0 K/BB. Tampa Bay has scored the fewest runs of any AL team – and he has a career 3.52 ERA against the Rays in four appearances (one start).

David Price, Rays (@BOS, MIN):Price (0-2) looks to turn it around this week against two teams he's historically pitched very well against. Last season against Boston, Price was 2-1 in three starts, with a 2.61 ERA and a 4.0 K/BB. In his only career start at Fenway, he picked up the win after allowing one earned run on two hits in six innings. Price is 0-1 in four career appearances (three starts) against Minnesota with a 1.69 ERA and an 11.0 K/9.

Keep 'em holstered

Jonathon Niese, Mets (COL, @ATL): Niese looked solid against the Marlins to start the season, but was pounded for six runs in just four innings against the Phillies. Following that up with Colorado and Atlanta is not a pleasing sight. Niese has struggled against the Rockies in his career with a 4.91 ERA and .301 BA allowed. While he's performed better against Atlanta (3.04 ERA), hitters have reached him for a .306 average and he allowed eight runs (three earned) in his one Turner Field start.

Edinson Volquez,Reds (@SD, PIT): Volquez's first start is in San Diego, where he has a history of pitching well, but he's pitched poorly in his first two starts. He's given up nine runs while walking seven batters in 11 innings. Don't touch him until he proves he has his groove back.

Alexi Ogando, Rangers (@DET, @NYY):Despite a near-perfect first start against Seattle (0 ER in six innings), Ogando is a risky play this week on the road. There isn't a whole lot of statistical data available on Ogando and it's better to leave him on the bench until he proves he can sustain his impressive start. (He may not even get a second start anyway, depending on what the Rangers do Wednesday afternoon.)

Brad Penny, Tigers (TEX, @OAK):For the second consecutive week, owners should avoid using Penny. In two starts, he is 0-1 with an 11.17 ERA, and he hasn't made it out of the fifth inning in either one. Things won't get any easier this week when he faces a Texas team that has scored the second-most runs in the American League.

To report corrections and clarifications, contact Standards Editor Brent Jones. For publication consideration in the newspaper, send comments to letters@usatoday.com. Include name, phone number, city and state for verification. To view our corrections, go to corrections.usatoday.com.

About Steve Gardner

Steve's been with USA TODAY in one form or another since 1993. He started
at USATODAY.com in 1996, becoming the website's baseball editor in 1999, and
has written the fantasy baseball column for Sports Weekly since 2006. Follow
him on Twitter: @sgardnerUSAT.