Reloading for wby 30-378 help!

Have owned this rifle for years have never found a solid reload. Currently trying 180gr Barnes ttsx bullets with h-50bmg powder fed215m primers. The rifle is wby m5. Can anybody give a starting point using these components. Seat depth,trim lenghth,powder charge, or just some place to start my loads. Have truer to address every problem concerning accuracy from copper fouling to inch pounds on set screws. Beginning to think there's no hope for it. Thanks in advance for any suggestions.