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Mouse in Biomedical Research by James G. Fox

Book Description

"Normative Biology, Husbandry, and Models", the third volume in the four volume set, "The Mouse in Biomedical Research", encompasses 23 chapters whose contents provide a broad overview on the laboratory mouse's normative biology, husbandry, and its use as a model in biomedical research. This consists of chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry. Other chapters cover management, as well as nutrition, gnotobiotics and disease surveillance. There are also individual chapters describing the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases. Chapters on imaging techniques and the use of the mouse in assays of biological products are also included.

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Dedicated to mouse immunology, this work presents an overview to mouse immunology, including both the innate and adaptive immune systems. It also illustrates the power of genetic engineering in dissecting each component of the immune response from the development of lymphoid tissues to signal transduction pathways in activated cells.

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