Osteoarthritis is a common joint disorder that is most prevalent in the knee joint. Knee osteoarthritis (OA) can be characterized by the gradual loss of articular cartilage (AC). Formation of lesion, fissures and cracks on the cartilage surface has been associated with degenerative AC and can be measured by morphological assessment. In addition, loss of… (More)

The onset of osteoarthritis (OA), a most common knee joint disease, can be characterized by the degeneration of articular cartilage (AC). Degenerative changes in AC have been assessed by the morphological and physiological measurements using non-invasive modality such as Magnetic Resonance Imaging (MRI) to obtain MRI images of the knee. However,… (More)

Early detection of knee osteoarthritis (OA) is of great interest to orthopaedists, rheumatologists, radiologists and researchers. It is possible to detect knee osteoarthritis by measuring changes in selected articular cartilage features using sensitive modalities. This paper identifies the modalities that can potentially assess changes in morphological,… (More)

Early detection of knee osteoarthritis (OA) is of great interest to orthopaedic surgeons, rheumatologists, radiologists, and researchers because it would allow physicians to provide patients with treatments and advice to slow the onset or progression of the disease. Early detection can be achieved by identifying early changes in selected features of… (More)

Knee osteoarthritis (OA) progression can be monitored by measuring changes in the subchondral bone structure such as area and shape from MR images as an imaging biomarker. However, measurements of these minute changes are highly dependent on the accurate segmentation of bone tissue from MR images and it is challenging task due to the complex tissue… (More)