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Tenvir-EM general information

What is Tenvir-EM used for?

Tenvir-EM tablets are a fixed dose combination treatment for Human Immunodeficiency Virus (HIV) infection in adults over age 18. Tenvir-EM tablets are used combination with other medications that have a different mechanism of action to the components in Tenvir-EM, and are used to treat patients with HIV infection who have either already received treatment with other medications for HIV or as first line therapy for treatment-inexperienced patients. HIV impairs the immune system by attacking specific immune cells called CD4+ cells that are involved in fighting infection and this can lead to opportunistic life-threatening infection (infections that would not normally be harmful); also if too many CD4+ cells are destroyed this can result in acquired immune deficiency syndrome (AIDS). Tenvir-EM tablets prevent or slow down the ability of HIV to replicate and spread, which keeps the amount virus down to a low level and this results in an increase in CD4 cell numbers, so that the immune system can recover, reducing the risk of disease progression.

How does Tenvir-EM work?

Tenvir-EM tablets contain a combination of two antiretroviral drugs, emtricitabine and tenofovir disoproxil fumarate, which are only effective against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). These drugs each work by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT), which is needed for the virus to be able to replicate. Retroviruses convert RNA to DNA, which is then integrated into the DNA of infected immune cells so that the virus can replicate. Emtricitabine and tenofovir disoproxil fumarate are both nucleoside analogue reverse transcriptase inhibitors (NRTI), which means that they are required for nucleosides to be transcribed into DNA by viral RNA. Competing to block the effects of RT, thereby incorporating the newly synthesized viral strand DNA and preventing its growth (chain termination). Emtricitabine is a cytidine analog and tenofovir is an adenosine analog. The combined action of these two antiretroviral drugs in Tenvir-EM tablets prevents the integration of the virus into the DNA of infected CD4+ immune cells, which inhibits HIV replication, thereby no longer producing viruses, and this reduces The amount of viral load virus). Tenvir-EM tablets slow the replication of HIV in the body, but do not kill the virus that has been integrated into CD4 + cells, nor does it prevent the spread of infection to others.

What does Tenvir-EM contains?

Tenvir-EM tablets contain two active ingredients, antiretroviral therapy emtricitabine (200 mg) and tenofovir disoproxil fumarate (300 mg) for the treatment of HIV infection.
Treating HIV infection with Tenvir-EM
Tenvir-EM tablets contain a combination of two antiretroviral drugs, emtricitabine and tenofovir disoproxil fumarate, for RNA viruses such as human immunodeficiency virus (HIV) (reverse transcription) Virus) is effective. HIV damages the immune system by attacking specific immune cell CD4 + cells involved in the fight against infection, which can lead to opportunistic life-threatening infections (usually not harmful infections), including pneumonia, herpes virus infections, and Mycobacterium avium complexes. (MAC) infection. If too many CD4+ cells are destroyed, it may lead to acquired immunodeficiency syndrome (AIDS). Both antiretroviral drugs in Tenvir-EM tablets are achieved by inhibiting the action of the virus-specific enzyme reverse transcriptase (RT), which is required for viral replication. Retroviruses convert RNA into DNA and then integrate it into the DNA of infected immune cells so that the virus can replicate. The combined action of two antiretroviral drugs in Tenvir-EM tablets prevents the integration of the virus into the DNA of infected CD4+ immune cells, which inhibits HIV replication, thereby no longer producing viruses, and this reduces the virus The amount of viral load). Tenvir-EM tablets slow the replication of HIV in the body, but do not kill the virus that has been integrated into CD4 + cells, nor does it prevent the spread of infection to others.

What are the side effects of Tenvir-EM?

The most common side effects when using Tenvir-EM include a headache, gastrointestinal discomfort (nausea, diarrhea, constipation, stomach pain), dizziness, fatigue, rash, difficulty sleeping, abnormal dreams, depression. A more serious but less common side effect is a condition known as lactic acidosis, which causes an excess of lactic acid in the blood due to liver damage, which may result in pancreatitis, liver failure or kidney failure.

What are the health risks when taking Tenvir-EM?

Lactic acidosis is a rare but potentially fatal disease reported when taking Tenvir-EM tablets. It is caused by excessive accumulation of lactic acid in the blood caused by liver damage.

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