The effect of hoisting load on transverse vibrations of hoisting catenaries during lifting in coal mines was investigated in this study. Firstly, dynamic analyses of the vertical hoisting rope were performed. The results show that transverse vibration plays the dominating role in the coupled dynamics of the vertical rope subjected to external excitation induced by axial fluctuations of head sheave, and the rope tension can be approximated by the quasistatic tension. Secondly, employing dynamic simulations, the effect of hoisting load on the transverse vibrations of hoisting catenaries was discussed. The results show that, under the second-order excitation frequency, a discrepant large transverse amplitude will be excited when the hoisting load ranges from 0 to 5000 kg, leading to collision between the two adjacent catenaries and accelerating the rupture of rope. To solve this problem, according to simulation curves, the self-weight of conveyance preload can be optimized from 39500 kg to 49500 kg. Eventually, on-site measurements were performed on the studied machine, validating the accuracy of the effect of hoisting load on transverse vibrations of hoisting catenaries. This investigation will greatly support facility maintenance, machine design, and even engineering optimization for floor type multirope friction mine hoists.