Tinidazole 500mg twice a day for 2 days once a month starting 3 months after commencement of Minocycline or Doxycycline. The first “pulse” should be just 1x500mg tablet, and in the second month take 2x500mg tablets. Then in the third month take the full dose. Metronidazole is an alternative to Tinidazole. After 6 months the interval between pulses may be reduced to 2 or 3 weeks.

Aspirin (Cartia) 100mg daily. This can be changed to Nattokinase, one capsule twice daily, after 6 months. Aspirin needs to be stopped at least 1 week before starting Nattokinase.

The initial treatment is generally for 12 months. After that treatment may be reduced to intermittent if deemed to be appropriate, but the NAC should be taken indefinitely to help prevent re-infection.

Further information on the CPn CAP protocol is available at:
http://davidwheldon.co.uk/ms-treatment.html