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Problem At 5% level, they are conspicuous on marrow smear and can be confused with neoplastic lymphoblasts

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Reference Ranges? No accepted reference ranges – BM examination is not performed in healthy people

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3 stages of Hematogone Maturation Early – Usually comprise a small minority, but can become expanded in regenerating marrows – No expression of CD 20 /CD34+ Intermediate – Majority in most marrows – -CD34-/CD20 dim/CD10+ Late – In contrast to mature B cells, Cd34-/CD20+/maintain dim CD10. Light chain surface+