Huntington's disease results in selective neurodegeneration in the forebrain and eventually death; there is currently no cure or therapy to slow its onset. Now, Ali Brivanlou and colleagues describe how isogenic stem cell lines with HTT repeat expansions give insights into the disease's cellular aetiology.

The resources pages of the Node and the BSDB have been combined and refurbished, with the new page designed to provide a range of useful links, including information on advocacy and outreach, new teaching resources for schools and databases for a wide range of species.