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The player automatically connects to the computer in Media Transfer Protocol mode (MTP mode).
For accessing the microSD card in the player, the USB connection in the player has to be set to MSC mode, see:http://kb.sandisk.com/app/answers/detail/a_id/167

Download the converter after you run the link below ....Put check next to converter/firmware update/Manual download...Go to your start menu programs go to sansa choose Sansa updater follow instructions.......(http://mp3support.sandisk.com/sansa/Installer/1082/SansaUpdaterInstall.exe) here is the link After installation connect your sansa......Also make sure you are connected to a 2.0 usb the back of the computer is best (the motherboard).... USB mode located on the sansa if asked to change to MSC goto menu press enter scroll to settings press enter scroll to usb mode press enter scroll to msc press enter press menu.....Connect should auto start sansa software..... Sansa software/driver Updates firmware follow instructions Downloads manual Downloads converter

if you go into the setting section of the menu you can select the USB mode back again, if this fails to solve the problem, take the back of the player off via 4 very small phillips screws and remove the battery for at least 30 seconds then put it back in and it should be good.

I would place the e260 in MSC mode first, as Vista should support this Sansa. Unplug the player, then from the e260 do the following: go to Settings, then choose System Settings then USB Mode & select MSC. Next, connect the E260, Vista should now see the player properly.