..Limited data suggest that CYP1A2 and CYP2D6 are involved in the metabolism of olanzapine. The purpose of this study was to further elucidate the role of these enzymes in the disposition of olanzapine in vivo...

Leptin concentrations are increased in subjects treated with clozapine or conventional antipsychotics

..This study examined if clozapine-treated subjects and subjects treated with conventional antipsychotics had increased leptin levels compared with the general population and whether there was a gender difference in this respect...

..Our cases suggest that long-term treatment with filgrastim might be a useful, but exceptional, treatment approach in patients who have developed clozapine-induced granulocytopenia or agranulocytosis...

Associations between venous thromboembolism and antipsychotics. A study of the WHO database of adverse drug reactions

..In previous studies the incidence of fatal adverse drug reactions in hospitalized patients has been reported, but the incidence of fatal adverse drug reactions in the general population is largely unknown...

High prevalence of the metabolic syndrome among a Swedish cohort of patients with schizophrenia

..5 days. The patient in this case recovered completely. Because the elimination time after intoxication can be considerably longer than expected, it is recommended that the patient's serum concentrations after intoxication be monitored...

Modelling drug-related morbidity in Sweden using an expert panel of pharmacists'

..In outpatients and in the general public corresponding data are limited, but pharmacists' expert opinion has suggested high rates of DRM also in US ambulatory care. It is unknown if the results are applicable in Sweden today...

Impact of information letters on the reporting rate of adverse drug reactions and the quality of the reports: a randomized controlled study