Rabbit Polyclonal| Catalog number: 10929-2-AP

Featured ProductKD/KO validated

Proteintech sets the benchmark for antibody validation.
Either we internally have validated the specificity of this antibody using siRNA KD
and/or there are published KD/KO data for this antibody (see Publications tab)

Background

The mammalian 5-prime-AMP-activated protein kinase (AMPK) appears to play a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. PRKAA1 is also named as AMPK1, ACACA kinase, HMGCR kinase. It is a mammalian homologue of sucrose non-fermenting protein kinase (SNF-1), which belongs to a serine/threonine protein kinase family. It has 2 isoforms with molecular mass of 63-66 kDa produced by alternative splicing.