Sponsor

This work was supported by the National Institute on Deafness and Other Communication Disorders at the National Institutes of Health (R21 DC010231; R01 DC012588).

Published In

Dyes and Pigments

Document Type

Citation

Publication Date

3-1-2016

Abstract

A series of geometrically well-defined cationic fluorophores were designed based on molecular mechanics. They contain biaryl linkers to impart rigidity preventing intramolecular folding between a conjugated biomolecule and fluorophore. All probes have absorption and emission maxima within 20 nm from Texas Red, as predicted by TDDFT calculations and validated experimentally.