Clinton and Affleck will speak at the gala along with US Department of Health and Human Services Secretary Kathleen Sebelius.

The Oscar-winning star said in a statement that he hopes the 'Child Survival' event will alert the public that the Democratic Republic of the Congo has the fifth highest rate of preventable deaths among children under 5 years old.

"We wouldn't allow 4-year-olds to die from preventable diseases in the US - nor should we let it happen in Congo or anywhere else," Affleck commented.