antineoplastic, antineoplastic drug, cancer drug - any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function

The product is intended to treat adult patients that have been recently diagnosed with glioblastoma multiforme, concomitantly with radiotherapy and then as maintenance treatment and also refractory anaplastic astrocytoma patients whose disease has progressed on a drug regimen containing nitrosourea and procarbazine.

Alkyl-ating chemotherapeutic agents, such as procarbazine and/or cyclophosphamide, cause prolonged azoospermia in 90%-100H of men and premature ovarian failure (POP) in 5%-25% of younger women under 30 years old; however, the risks are low with radiotherapy alone if pelvic radiation or chemotherapy with alkylating agents is not given (22).

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