So for any given exercise, 4 sets of 15-20 reps with 60″ (1 minute) rest might be done. Alternately, two different exercises might be alternated with a very short rest period with a slightly longer rest interval between exercise each pairing.

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whether this is a direct effect via blood flow or lactate is debatable, it may simply be an issue of giving the joins a break from endless heavy training.

Perhaps more accurately, athletes who make the best strength gains in a moderate repetition range combined with sufficient food tend to grow the best.

Casey Butt wrote something similar, he basically stated the you might be able to increase your low reps quite a bit without much hypertrophy, but it's not likely to happen like that at medium reps.

Given that sacroplasmic hypertrophy does fulfil a useful function, as glycogen will increase a muscles endurance, I don't really see how it can considered non-functional. I realise it's not your definition.

The problem that I see is that progressing in one of the three hypertrophy factors (tension, fatigue, damage) can't be done without limiting the others. I mean that if you focus on tension increases, you can't do too much volume (fatigue) or superslow eccentrics (damage). If you focus on fatigue, you wont progress much in weigth increases (tension).

Probably the best would be to focus on one factor at a time, and let the others at maintenance.