MacFarlane: There are things I don’t like about FOX, most notably Fox News, but [Rupert] Murdoch is clearly a shrewd businessman first and a conservative second…He seems to be much more of a critical thinker than the guys he employs at Fox News. If Sean Hannity could think as critically as Rupert, I might like him.

When asked about how his success is helping pay the salaries of Hannity and Bill O’Reilly, McFarlane responded: “I guess if some of it could go toward hiring a dermatologist for O’Reilly and a dietitian for Hannity, I’d feel better about it.” Zing!

As far as appearing on Fox News, MacFarlane went on to say, “I would do it in a second. I love arguing with people I disagree with. Those guys are fundamentally wrong about so much, but they’re also superb debaters.”

Apparently, MacFarlane’s biggest show, “Family Guy,” is about to get a little more political this season. He recently toldThe Hollywood Reporter that Karl Rove and Rush Limbaugh will be playing themselves in upcoming episodes.