Welcome

Welcome to the POZ/AIDSmeds Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and
others concerned about HIV/AIDS. Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the
conversation yourself by registering on the left side of this page.

Privacy Warning: Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive
and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a
username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own
physician.

All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators
of these forums. Click here for “Am I Infected?” posting guidelines. Click here for posting guidelines pertaining to all other POZ/AIDSmeds community forums.

We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please
provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are
true and correct to their knowledge.

Author
Topic: Question about superinfection (Read 17005 times)

So, let's say 2 guys are getting it on unprotected with 2 different strains of HIV and both are undetectable and on HAART. Superinfection would seem to be impossible right? I know with an undetectable viral load infection is less likely and I would conjecture that the HAART regimen they are on would work like PEP and destroy any incoming virus?

Right I get that part, but assuming the Haart regimen his partner is on is not what his virus is resistant to I would assume his meds would act as pep for the virus meaning super infection couldn't occur.

Are you asking this in light of mutations in case you want to bareback with me?

Yes, of course. Actually at the 2012 "End-of-the-world" planning orgy committee this question came up about the barebackin and all. I just thought I should be responsible and ask for everyone's benefit.

Right I get that part, but assuming the Haart regimen his partner is on is not what his virus is resistant to I would assume his meds would act as pep for the virus meaning super infection couldn't occur.[/quote

Different strains can be resistant to different drugs. For example 3DCR is resistant to three of the four types of antivirals

Are you asking this in light of mutations in case you want to bareback with me?

Two voracious bottoms barebacking? How is that even possible? Pancakes.

Logged

"I have tried hard--but life is difficult, and I am a very useless person. I can hardly be said to have an independent existence. I was just a screw or a cog in the great machine I called life, and when I dropped out of it I found I was of no use anywhere else."

I've gotten a lot of conflicting info about super-infection. The HIV pharmacist at the practice I go to says she sees it all the time--especially in partners who are both poz. I read Dr. Gallant and docs on thebody say they think it is very, very rare for people who've been poz for several years. They say it usually happens with people newly infected. So, I remain confused as usual..lol.

I've gotten a lot of conflicting info about super-infection. The HIV pharmacist at the practice I go to says she sees it all the time--especially in partners who are both poz. I read Dr. Gallant and docs on thebody say they think it is very, very rare for people who've been poz for several years. They say it usually happens with people newly infected. So, I remain confused as usual..lol.

Mary please -- you can find conflicting information on how to tie shoes too. Who are you going to believe, the pharmacist or Gallant? Come on.

I've gotten a lot of conflicting info about super-infection. The HIV pharmacist at the practice I go to says she sees it all the time--especially in partners who are both poz. I read Dr. Gallant and docs on thebody say they think it is very, very rare for people who've been poz for several years. They say it usually happens with people newly infected. So, I remain confused as usual..lol.

I'm just stuck at the idea that you have an HIV speciality pharmacist who talks to people.

And they are not even based in India?

A (whose pharmacist appears to be a web ap -- and not one of the brighter ones)

In NSW there is a character called the Chief Pharmacist in HIV, but he only consults with prescribers and hospital pharmacists. The latter since HIV medications can only be dispensed from hospital pharmacies here.

So, let's say 2 guys are getting it on unprotected with 2 different strains of HIV and both are undetectable and on HAART. Superinfection would seem to be impossible right? I know with an undetectable viral load infection is less likely and I would conjecture that the HAART regimen they are on would work like PEP and destroy any incoming virus?

Just curious if that makes sense or not.

\

Don't know exactly, but personally I just don't buy any of this super duper squared infection stuff. My wife and I have been on two different regimens and also on the same regimen, different times of course, and I don't like condoms... and I don't like to pull out. Nothings come of it so far, she's been undetectable during our whole relationship. Both of our Cd4's have been 1000+, hers the whole time, while I steadily climbed from a count of 103..

We've been together for 4 years now and have had lots of nasty fi.. um sex.

Don't know exactly, but personally I just don't buy any of this super duper squared infection stuff. My wife and I have been on two different regimens and also on the same regimen, different times of course, and I don't like condoms... and I don't like to pull out. Nothings come of it so far, she's been undetectable during our whole relationship. Both of our Cd4's have been 1000+, hers the whole time, while I steadily climbed from a count of 103..

We've been together for 4 years now and have had lots of nasty fi.. um sex.

Hold on back this up. You're a man...and she's not a man? And you had sex? Can you start from the beginning? I'm totally lost.

Hold on back this up. You're a man...and she's not a man? And you had sex? Can you start from the beginning? I'm totally lost.

Seriously? You didn't know that he ain't family? I mean, he did try dick once, but it apparently didn't go so well.

Logged

"I have tried hard--but life is difficult, and I am a very useless person. I can hardly be said to have an independent existence. I was just a screw or a cog in the great machine I called life, and when I dropped out of it I found I was of no use anywhere else."

Mary please -- you can find conflicting information on how to tie shoes too. Who are you going to believe, the pharmacist or Gallant? Come on.

I would trust Dr. Gallant. I don't even like the HIV pharmacist. She is so condescending. She is also the one who told me when I first came to the office that she was totally sure I was HIV neg and had gotten a false/positive. When it came back poz again, she changed her story and acted like she didn't say that.

She still says she has couples who develop their partner's resistance to meds after not having them before. Is this different from super-infection? I am from KY you know.

I would trust Dr. Gallant. I don't even like the HIV pharmacist. She is so condescending. She is also the one who told me when I first came to the office that she was totally sure I was HIV neg and had gotten a false/positive. When it came back poz again, she changed her story and acted like she didn't say that.

She still says she has couples who develop their partner's resistance to meds after not having them before. Is this different from super-infection? I am from KY you know.

Ted, if she changed her story about something you knew to be true, then why are you thinking she's telling you the truth about these alleged couples? Sounds to me like she's full of the poopie-stuff.

"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

also, just how would the pharmacist know that these people supposedly had "super infection" issues, without being privy to people's medical records? Because they changed meds??? That's not a very good indicator. The only medical advice I take from my pharmacist concerns side-effects, not treatment regimen suggestions

also not mentioned yet I think, is about the next to nil chance of any infection occuring when partners are undetectable. If a person with an undetectable viral load cannot pass on the infection, then how could any reinfection or super infection even occur? (If your pharmacist is truly seeing this "super infection" occuring then she must only be dealing with probably newer patients who have higher viral loads and are beginning treatment)

in that scenario, neither partner was on meds at all (much less off meds sufficiently to cause resistance mutations to occur) so I don't see why they would even worry about superinfection. More than likely one partner was infected and passed it along to the other partner, so both would have the same virus with identical mutations (if any).

of course, people are talking about it (ie superinfection) recently. Superinfection seems to be the newest buzz word. (IMHO, You can't forget either, that in America, we're living in a "society of fear" anymore where "boogey men" have to be created to keep us fearful and our actions under control.) Since more than likely superinfection is only happening between people who have never been diagnosed, or between people not on treatment with higher viral loads, I would venture to say that the amount of superinfection will always be a small percentage. The easiest "cure" for superinfection is to have a genotype test done prior to starting on meds (so you get the proper meds taking into account the multiple mutations of your "superinfection') and once on meds to get your VL to undetectable so as not to spread your mutation around.

I always keep something in mind, Ted, that Ann says over in the Am I Infected forum alot. There are enough people in these forums for long enough that though some of this stuff may be theoretical, the actuality is usually nil, otherwises we'd be seeing those issues in members here after 20 yrs or more.

Yeah I was just asking so that hopefully I can put my fears of reinfecting another pozzie aside should I decide to do the deed without a parachute. Of course me having sex at this point is purely theoretical as well.

Yeah I was just asking so that hopefully I can put my fears of reinfecting another pozzie aside should I decide to do the deed without a parachute. Of course me having sex at this point is purely theoretical as well.

just like the straights with UD VL can have sex and get pregnant without passing along any virus, the same "should" hold true for gays. I mean how can an UD VL be passed on (ie reinfection)?

all my partners keep dying from AIDS but I keep finding more. Though I didn't have any sex for the last 8 month my last partner was alive (not much libido when you're sick and dying I would imagine) and didn't have any sex for 2 yrs afterwards while I grieved and moved from home to home, I've been getting me some nice ass lately from a fellow pozzie I met after moving to SC (thank you a4a LOL). Maybe you just need to move to another state. ROFLMAO

Yeah I was just asking so that hopefully I can put my fears of reinfecting another pozzie aside should I decide to do the deed without a parachute. Of course me having sex at this point is purely theoretical as well.

"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

LOL... I respect the good doctor, but I'm still pissed over them not answering my question as to whether I was infected or not back in 05, when I thought I was just a lowdown worried well. I posted like 75 times and he kept replying to the guys before and after me..

No I have a particular Philadelphian squarely in my sights. I'm just now crushing up the roofies to get them into powder form and put them in the mail.

Way to scare them off!

j/k, good luck..

Logged

It's all a sham. Politics is a big game, same as the media - and same as religion. The point is to distract & control. If we're looking at what they tell us is the "big issue", we're not looking at what they are doing. In time, there will be different causes and different minorities to pick-on. All in the name of keeping the system going, and the people distracted.

Many drugs which are fine for HIV1, aren't effective when HIV2 is involved.

HIV-2 is rare in Europe, but the German singer had it, which made the transmission easier to trace and confirm. Had she had HIV-1, it might have been more difficult to say that it was she who infected her ex-partner.

Many drugs which are fine for HIV1, aren't effective when HIV2 is involved.

HIV-2 is rare in Europe, but the German singer had it, which made the transmission easier to trace and confirm. Had she had HIV-1, it might have been more difficult to say that it was she who infected her ex-partner.

I don't follow the logic of HAART which is effective against HIV1 would not be effective against HIV2 unless perhaps HIV2 has some sort of resistance to one class or a couple of classes of drugs? Can you link something that backs up that statement?

well trey my doc told me not to have sex with another poz she said I could get in bad trouble I left it at that,i get the picture. Made the wrong mistake once

So she suggests that you have sex with neggies only (I can see that manhunt profile: "HIV+ here, U B neg")? Or is she suggesting that you take some HIV celibacy vows?

« Last Edit: September 02, 2010, 02:38:25 PM by Rev. Moon »

Logged

"I have tried hard--but life is difficult, and I am a very useless person. I can hardly be said to have an independent existence. I was just a screw or a cog in the great machine I called life, and when I dropped out of it I found I was of no use anywhere else."

I don't follow the logic of HAART which is effective against HIV1 would not be effective against HIV2 unless perhaps HIV2 has some sort of resistance to one class or a couple of classes of drugs? Can you link something that backs up that statement?

Quote

In vitro (laboratory) studies suggest that nucleoside analogs are active against HIV-2, though not as active as against HIV-1. Protease inhibitors should be active against HIV-2. However, non-nucleoside reverse transcriptase inhibitors (NNRTIs) are not active against HIV-2.

My partner is also afraid of superinfection so he won't let me cum in him. All I have to say is...If reinfection was real, there's no way I wouldn't have it. I demand all my tops to either cum in my ass or my mouth. I don't have sex for the good feeling. I endure it for the creamy ending.

My partner is also afraid of superinfection so he won't let me cum in him. All I have to say is...If reinfection was real, there's no way I wouldn't have it. I demand all my tops to either cum in my ass or my mouth. I don't have sex for the good feeling. I endure it for the creamy ending.