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The league’s new guard has no problem speaking out — in no uncertain terms — against performance-enhancing drugs and the players who use them.

Los Angeles Angels star Mike Trout is just the latest union member to speak out about the need for baseball’s ultimate penalty: one strike and you’re out.

“To me personally, I think you should be out of the game if you get caught,” Trout told WFAN’s Boomer Esiason and Craig Carton on Monday. “It takes away from the guys that are working hard every day and doing it all-natural.”