Fluticasone side effects

Fluticasone is a synthetic pharmaceutical corticosteroid (Glucocorticoid), a steroid hormone derivative. It is available under the generic name Fluticasone propionate and brand names such as Flonase, Cutivate and Flovent etc. It is chemically belongs to the class of steroid esters and as S-(fluoromethyl)6α,9-difluoro-11β-17-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carbothioate, 17-propionate. The Fluticasone acts as a potent antagonist of glucocorticoid receptors and inhibits the multiple immune system cells (e.g. neutrophils, macrophages, eosinophils, and lymphocytes). It also prevent the release of inflammatory substances such as Histamine, Cytokines, Prostaglandins, Tryptases, Chemokines and Leukotrienes. It is used to treat allergic and inflammatory conditions such as skin problems (i.e. allergic reaction, dermatoses, eczema and psoriasisallergic), rhinitis, asthma, and nasal polyps.

Fluticasone may be associated with a number of side effects which may need the medical attention. If you encounter the side effects you should contact your doctor or healthcare professional immediately. These side effects can be rare, incidence not known, less common, or more common.

Rare side effects includes

Heart problems

High blood pressure

Chest tightness

Trouble in breathing

Bone fracture

Skin rashes and hives

Blurred vision, eye pain and blindness

Increase in hunger or thirst

Frequent urination

Weakness

Excessive growth of facial hair in women

Swelling of the lips, eyelids, or face

growth reduction in children

Male impotence

Lack of menstrual periods

Incidence not known

Fast heartbeat

Dizziness

More common side effects include

White patches on throat

Patches in the mouth

Less common side effects include

Vomiting

Nausea

Diarrhea

Ache in ear and stomach

Trouble in swallowing

Fever

Pain on urination

Redness or discharge of the eye

Shortness of breath

Sore throat

White discharge from vagina

Sometimes, cases of overdose may be encountered while taking Fluticasone which seeks immediate emergency help. The Symptoms of overdose includes: extreme weakness, skin darkening, loss of appetite, fainting, and mental depression. A few side effects go away by body adjustments while taking medicine. Contact your doctor in case of any queries or if side effects continue.

Rare

Restlessness

Weight gain

Aggression or agitation

Itching

Incidence not known

Dry mouth and skin

Blurred vision

Weight or voice loss

Pain in the body parts

Fruity odor in breath

Sweating

Decrease in height

Trouble in sitting still

More common

Voice changes

Cough

General body aches

Colored mucus in nose

Headache

Runny, stuffy, or sore nose

Less common

Nosebleeds

Eye irritation

Fainting

Headache or stomach pain

Disturbed menstrual periods

Pain in joints

Mouth irritation

Sneezing

The long term side effects of Fluticasone may be as follows:

Local side effects include sore throat, eye irritation, chest or nasal congestion, nasal discharge, and bronchitis.

Hypersensitive reactions usually come into play when there is any shift in the oral corticosteroid therapy after introduction of Fluticasone. These include systemic eosinophilic condition and anaphylactic reactions including cardiac complications, vasculitis and vasculitic rashes, neuropathy, and worsening pulmonary symptoms; rare cases of immediate and delayed reactions such as bronchospasm, rashes, and angioedema.

Ocular side effects are often associated with long use and include cataracts, increased risk of glaucoma and ocular hypertension.

Nervous system side effects comprise dizziness, insomnia, fatigue, and headache.