Genetics

Being the inquisitive type in Jan 2015 I decided to use one of the mail order saliva dna tests. I am happy to say I am relatively free of debilitating diseases lol. The test cost £125 and the sample shipped to Holland and took about 3 weeks for the initial results to be made available. I'm not quite sure what to make of the results because they predicted my eye colour as probably being blue (although I guess they were blue as a baby but are now green) and categorise me having decreased odds of being bald. A lot of the items won't mean a lot to anybody else much without the full report.

Ancestry

Genetic Risk Factors

These reports show your results for specific genetic variants that are associated with a higher risk for developing certain health conditions. Environmental and lifestyle factors can also contribute to these conditions.

Drug Response

This section displays status with regard to genetic variations that have been linked to differences in how people respond to drugs. These may be differences in sensitivity or in the likelihood or severity of side effects.

Name

Confidence

Status

Warfarin Sensitivity

Increased

Clopidogrel Efficacy

Reduced

Phenytoin Sensitivity (Epilepsy Drug)

Increased

Proton Pump Inhibitor (PPI) Metabolism

Intermediate

Pseudocholinesterase Deficiency

Increased

Sulfonylurea Metabolism

Reduced

Abacavir Hypersensitivity

Typical

Acetaldehyde Toxicity

Typical

Fluorouracil Toxicity

Typical

Hepatitis C Treatment Response

Typical

Simvastatin-Induced Myopathy

Typical Risk

Thiopurine Methyltransferase Activity

Likely Typical (Normal Activity)

Inherited Conditions

These reports show results for specific genetic variants that can cause certain health conditions. Many of these conditions are recessive, meaning that they only occur when you have two variants for that condition, one inherited from each parent. If you have inherited just one variant, you are said to be a "carrier". Carriers usually do not have the condition, but can pass the variant on to their children.

Name

Confidence

Status

Cystic Fibrosis

Variant Present

ARSACS

Variant Absent

Agenesis of the Corpus Callosum with Peripheral Neuropathy (ACCPN)

Variant Absent

Autosomal Recessive Polycystic Kidney Disease

Variant Absent

Beta Thalassemia

Variant Absent

Bloom's Syndrome

Variant Absent

Canavan Disease

Variant Absent

Congenital Disorder of Glycosylation Type 1a (PMM2-CDG)

Variant Absent

Connexin 26-Related Sensorineural Hearing Loss

Variant Absent

D-Bifunctional Protein Deficiency

Variant Absent

DPD Deficiency

Variant Absent

Dihydrolipoamide Dehydrogenase Deficiency

Variant Absent

Familial Dysautonomia

Variant Absent

Familial Hyperinsulinism (ABCC8-related)

Variant Absent

Familial Mediterranean Fever

Variant Absent

Fanconi Anemia (FANCC-related)

Variant Absent

G6PD Deficiency

Variant Absent

GRACILE Syndrome

Variant Absent

Gaucher Disease

Variant Absent

Glycogen Storage Disease Type 1a

Variant Absent

Glycogen Storage Disease Type 1b

Variant Absent

Hereditary Fructose Intolerance

Variant Absent

Junctional Epidermolysis Bullosa (LAMB3-related)

Variant Absent

Leigh Syndrome, French Canadian Type (LSFC)

Variant Absent

Limb-girdle Muscular Dystrophy

Variant Absent

Maple Syrup Urine Disease Type 1B

Variant Absent

Medium-Chain Acyl-CoA Dehydrogenase (MCAD) Deficiency

Variant Absent

Mucolipidosis IV

Variant Absent

Neuronal Ceroid Lipofuscinosis (CLN5-related)

Variant Absent

Neuronal Ceroid Lipofuscinosis (PPT1-related)

Variant Absent

Niemann-Pick Disease Type A

Variant Absent

Nijmegen Breakage Syndrome

Variant Absent

Pendred Syndrome

Variant Absent

Primary Hyperoxaluria Type 2 (PH2)

Variant Absent

Rhizomelic Chondrodysplasia Punctata Type 1 (RCDP1)

Variant Absent

Salla Disease

Variant Absent

Sickle Cell Anemia

Variant Absent

Sjögren-Larsson Syndrome

Variant Absent

Tay-Sachs Disease

Variant Absent

Tyrosinemia Type I

Variant Absent

Usher Syndrome Type I (PCDH15-related)

Variant Absent

Usher Syndrome Type III

Variant Absent

Zellweger Syndrome Spectrum

Variant Absent

Traits

Some of our physical attributes are completely determined by genetics while others are influenced by many genetic as well as non-genetic factors.