Publication History

The recently introduced On Demand Enteroscopy system (ODE; NaviAid AB, Smart Medical Systems, Ra’anana, Israel) enables deep small-bowel enteroscopy using standard endoscopic equipment. The ODE device consists of a disposable balloon that is advanced through the working channel of a standard endoscope equipped with a working channel of at least 3.8 mm ([Fig. 1]). To the best of our knowledge, there are currently no published reports on the use of this new technique.

Fig. 1 a The disposable parts of the On Demand Enteroscopy (ODE) system for balloon-assisted enteroscopy. b The disposable, inflated ODE balloon at the tip of the scope.

A 64-year-old man presented with abdominal pain, anemia and positive hemoccult. His physical examination was unremarkable and the laboratory parameters were within the normal reference ranges, except for a low hemoglobin level (10.2 g/dL). Celiac disease and lactose intolerance had already been ruled out and previous esophagogastroduodenoscopy (EGD) and colonoscopy had not revealed any bleeding source. In view of the positive hemoccult but negative upper and lower endoscopic examinations, a decision was made to use ODE deep small-bowel enteroscopy. The endoscope was advanced into the distal duodenum, and the ODE system was inserted through the working channel of the endoscope (Pentax i10 L, Tokyo, Japan) and advanced ahead of the endoscope inside the small intestine. Next, the balloon at the distal tip of the ODE device was inflated. Once the balloon was completely inflated, the endoscope was pushed forward while the anchored balloon was pulled gently backwards. The small-bowel was straightened with the inflated balloon placed at the distal tip of the endoscope while the endoscope was gently pulled backwards. This approach allowed us to introduce the endoscope within 12 minutes to a maximum length of 180 cm from the pyloric region. The next advancement step revealed a huge (20-mm diameter) diverticulum ([Fig. 2]) which had come to be situated next to the inflated balloon during the last pulling operation, however, there were no signs of mucosal damage. The endoscope was carefully advanced and several more large-sized diverticula were found at approximately 200 cm from the pyloric region ([Fig. 3] and [Video 1]).

Fig. 2 Massive diverticulum next to the inflated balloon, approximately 180 cm from the pyloric region, in a 64-year-old man with abdominal pain, anemia and positive hemoccult.Fig. 3 Diverticular sacs with mucosal atrophy and distorted vascular pattern.

Extensive small-bowel diverticulosis clearly seen in the deep small bowel.

This case report is interesting for multiple reasons. First, we have given a detailed description of the procedure employing the newly introduced ODE system, which may assist with further use of this technique. Second, our report adds to the growing literature on advanced endoscopic imaging methods for the small bowel [1]
[2]. Lastly, we have demonstrated the safety of the ODE system while identifying an unusual case of small-bowel diverticulosis [3]
[4].

Fig. 1 a The disposable parts of the On Demand Enteroscopy (ODE) system for balloon-assisted enteroscopy. b The disposable, inflated ODE balloon at the tip of the scope.Fig. 2 Massive diverticulum next to the inflated balloon, approximately 180 cm from the pyloric region, in a 64-year-old man with abdominal pain, anemia and positive hemoccult.Fig. 3 Diverticular sacs with mucosal atrophy and distorted vascular pattern.