We each have two number 15 chromosomes, one inherited from our mother (M.) and one inherited from our father (P, paternal). The Angelman syndrome gene (UBE3A) is located at chromosome 15, band q12, as depicted. In the brain, the Angelman gene is primarily expressed from the maternally inherited chromosome 15. The diagrams below illustrate the four known genetic mechanisms that cause Angelman syndrome. Continue Reading →

Newly Diagnosed?

Has someone in your family been recently diagnosed with Angelman syndrome? Fill out this simple form if you would like to receive more information on AS.

The Angelman Syndrome Foundation is the largest non-governmental funder of Angelman syndrome-specific research. It is our hope that these funded researchers, and their collaborators and peers, will bring forth new discoveries that ultimately lead to treatments and a cure.

The ASF has partnered with leading medical and research institutions, to found the Angelman Syndrome Clinics, a “one-stop-shop” medical and psychosocial resource from birth through adulthood. Each clinic has its own unique capabilities that leverage the expertise and specialized care available from each partnering organization.

Visual Memory

When our daughter was three years old (she is now 33) she began taking a bus to school. One day, the bus had to take a different route home. The driver told us that our daughter began wailing and seemed to know that the driver was going the wrong way! After a similar incident happened again, we realized this wasn’t a coincidence. She had remembered/memorized everything along the route! I believe this is common in our angels and it should teach us that this visual modality is vital. It, no doubt, offers them comfort in routines and stability. It also seems that our angel has great facial recognition, too!Alice and Mark Evans San Diego, CA angel Whitney, age 33

Vitamins

Our 35 year-old son takes vitamin C and a multivitamin and is quite healthy. He does have allergies like other family members and catches viruses at his day program, but he recovers in a short amount of time.Susan Pike

Vitafusion Fiberwell Gummies (Can be purchased at pharmacies, as well as Walmart, Target, etc.

This chewable supplement provides 5 grams of fiber; has a peach, strawberry and blackberry flavor; and can be cut in half for easier chewing.)

Vitafusion Multi-Vitamin Gummies (Can be purchased at pharmacies, as well as Walmart, Target, etc. This fruit-flavored chewable supplement can be cut in half for easier chewing.)