ROSEMONT, Ill. -
St. John's shot 47.5 percent (28-of-59) from the floor and used a 17-6 second half run to take a 74-70 lead with 4:35 left in regulation, but missed its final five field goals and was defeated by DePaul, 77-75, on the road in a game that featured 16 ties and 15 lead changes.

D'Angelo Harrison made 4-of-6 3-pointers and reached the 20-point plateau for the ninth time this season to lead St. John's (9-7, 0-4) with a game-high 24 points. Rysheed Jordan added 16 points and six rebounds, while Orlando Sanchez chipped in with 11 points and five boards to give the Red Storm three players in double-figures. St. John's shot 50.0 percent (7-of-14) from beyond the arc and 80.0 percent (12-of-15) from the line, but matched a season-high with 13 turnovers and finished -6 (32-38) on the glass.

"We are naturally disappointed with this result. Our kids were able to rally in the second half from down seven to build a four-point lead, but we were not productive in the closing stage of the game," said St. John's head coach Steve Lavin. "On our final possession down one, we would have preferred to have had action going to the rim, but we now must move on and get ready to play Providence on Thursday."

Billy Garrett scored 21 points to lead DePaul (10-8, 2-3), while Cleveland Melvin added 16 points, seven boards and six blocks. Brandon Young scored 19 points and Tommy Hamilton chipped in with 13 to give the Blue Demons four players in double figures. DePaul shot 40.3 percent (25-of-62) from the floor and finished 6-of-18 (33.3 percent) from long range after rebounding from a 1-of-9 first half effort from distance.

Neither team led by more than three points in the second half until a pair of Garrett free throws gave DePaul a 59-55 lead with 13:57 to left in regulation. The Blue Demons led by seven, 64-57, with 12:20 to go before Harrison converted a 3-point play to open an 11-3 run that was capped by a Sanchez 3-point play and gave the Red Storm a 68-67 lead at the 8:29 mark. With the game tied again at 70-70, Harrison made a layup and a jumper to give St. John's a 74-70 lead with 4:35 to play. St. John's still led by three, 75-72, after Jordan made 1-of-2 free throws with 3:48 to play. The Red Storm, however, missed its final five field goals, including a halfcourt heave at the final buzzer.

A quick 6-0 run saw DePaul jump out to an early 10-4 lead before a Harrison 3 opened up a 9-2 run as St. John's went up 13-12 with 14:21 remaining. After the Blue Demons went back up by five, Harrison answered again with a 3 and a Chris Obekpa layup tied the game at 22-22 with 9:33 left. JaKarr Sampson followed with a layup and a pair of throws before a Jordan trey gave St. John's its largest lead of the game, a 29-24 advantage with 7:16 to go in the opening frame. A Max Hooper 3 gave the Red Storm a 38-36 lead with 34 seconds left, but a Young jumper tied the game for the eighth time and the teams went into the locker room level at 38-38.

St. John's continues its stretch of three games in five days as the Red Storm plays host to fellow founding BIG EAST member Providence in Queens (Thursday, Jan. 16, 7 p.m. FOX Sports 1).