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This chapter presents a case study to show the necessary skills, attitudes, and background required to diagnose and manage cancer pain. It describes the use of three agents that have been employed in this setting — methadone, ketamine, and cannabinoids. It examines a number of questions such as: What is the pain diagnosis? What are the likely mechanisms of pain? How does methadone work as an analgesic? What are the main indications for the use of methadone? What are the reported mechanisms of analgesic effect of ketamine? What are the problems associated with the use of ketamine? What is the...

This chapter presents a case study to show the necessary skills, attitudes, and background required to diagnose and manage cancer pain. It describes the use of three agents that have been employed in this setting — methadone, ketamine, and cannabinoids. It examines a number of questions such as: What is the pain diagnosis? What are the likely mechanisms of pain? How does methadone work as an analgesic? What are the main indications for the use of methadone? What are the reported mechanisms of analgesic effect of ketamine? What are the problems associated with the use of ketamine? What is the evidence that cannabinoids are useful for managing pain?