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Men who choose to wear a brassiere may broadly be divided into two categories, depending on whether the brassiere is worn primarily for utilitarian purposes. Some men who have large breasts as a result of obesity or gynecomastia may choose to wear a brassiere to provide support for their breasts and to flatten their appearance. Other men wear bras for cross-dressing, for sexual purposes such as transvestic fetishism or feminization, or as a form of submission to their partner.

Petticoat discipline may also involve male bra wear. Additionally, some male athletes – more specifically runners – may choose to wear a sports bra under their shirts in order to prevent a common medical condition called jogger's nipple, also known as nipple chafing. This condition is caused by excessive rubbing of wet sweat-soaked material over one's nipples. The condition, often very painful, can be prevented by wearing a sports bra.