The feds have smoked out a synthetic marijuana manufacturing center doubling as a tire repair shop in Queens, seizing $200,000 worth of the deadly drug and arresting a woman wanted on a narcotics warrant, law enforcement sources said.

Agents from the FBI and the Drug Enforcement Administration swooped down on Excellent Tire Shop Services in Queens Village on Tuesday night, sources said, adding that the NYPD and the New York State Police assisted in the raid.

After storming the facility, the investigators rushed to a back room, where they discovered the manufacturing site behind a plastic tarp and approximately 170 kilograms of alleged synthetic cannabinoids, the sources said.

The chemical-laced marijuana, better known as “K2” or “Spice,” has quickly become a favorite among young pot smokers and the homeless due to the cheap purchasing price of $5 at local bodegas. It’s considered a mind altering drug that’s been responsible for thousands of emergency room visits in New York City.

Federal investigators also found industrial quantities of the chemicals used to manufacture the drug as well as scales, packaging materials, flavoring agents and a sizable amount of processed cannabinoids that had not yet been packaged for sale, sources said.

A total of 200 kilograms of “K2” was recovered at the tire shop with a street value of at least $200,000, sources said.

Osvaldo Maria Vasquez, who was being sought on a warrant for cocaine distribution, was arrested at the facility Tuesday night. She was awaiting arraignment late Wednesday at the federal courthouse in Brooklyn.

DEA Special Agent in Charge James J. Hunt said the takedown came before the devastating drug could hit the streets.

“Rearing its ugly head, synthetic cannabinoids were being manufactured and packaged with intentions to be unleashed in our city,” Hunt said in a statement. “Due to good police work, a clandestine K2 lab was dismantled in Queens, demolishing the health and the societal dangers caused by K2 use along with it.”

Brooklyn US Attorney Robert Capers warned that “Spice” presents a “new danger to public health.”

“Last night’s seizure by the FBI and DEA represents another step in law enforcement’s response to this deadly serious problem,” Capers added.