WHO- Risk Factors for Killer Disorders (NCD´s)

In the featured article on the front page, I showed a slide from the WHO (World Health Organization), depicting the leading factors for the premature deaths on the Globe. Link Here In this slide hypertension figured prominently as main root cause of all premature deaths. I find this somewhat unusual for a condition, which is recognized as idopathic (unknown causes) for about 95% of all cases. There are risk factors for hypertension defined and they are all over the place, mainly genetic disposition, age, obesity, salt, alcohol, diabetes and vitamin deficiency. But that chart was from 2004, nowadays, it does not have that "prominent place" in the list of leading factors, which makes sense to me.

Of course- hypertension is still a big issue, but hardly a predominant factor.

Having cleared that, we can turn to those root causes or leading factors that the WHO nowadays sees as major risk factors for the six major NCD´s (Non-Communicable Disorders) and here I quote from their Homepage:

Major NCDs and their risk factors

Noncommunicable diseases (NCDs), including heart disease, stroke, cancer, diabetes and chronic lung disease, are collectively responsible for almost 70% of all deaths worldwide. Almost three quarters of all NCD deaths, and 82% of the 16 million people who died prematurely, or before reaching 70 years of age, occur in low- and middle-income countries.

The rise of NCDs has been driven by primarily four major risk factors: tobacco use, physical inactivity, the harmful use of alcohol and unhealthy diets.

The epidemic of NCDs poses devastating health consequences for individuals, families and communities, and threatens to overwhelm health systems. The socioeconomic costs associated with NCDs make the prevention and control of these diseases a major development imperative for the 21st century.

WHO’s mission is to provide leadership and the evidence base for international action on surveillance, prevention and control of NCDs. Urgent government action is needed to meet global targets to reduce the burden of NCDs.

Fortunately (just from a timing perspective for this page) the WHO started to work on the issues and organized a big conference in Montevideo, Uruguay, where representatives from all over this globe gathered and managed to hammer out a "Roadmap" for the governments of the world to fight the stated issues. See Conference Logo on the right. This roadmap you will find in the download section below. Key statements as a result of this conference were as follows:

18 OCTOBER 2017 | MONTEVIDEO - Heads of State and Government and ministers from around the world today committed to new and bold action to reduce suffering and death from noncommunicable diseases (NCDs), primarily heart and lung diseases, cancers and diabetes, the world’s leading killers.

Governments endorsed the Montevideo Roadmap 2018-2030 on NCDs as a Sustainable Development Priority at the opening of the three-day Global Conference on Noncommunicable Diseases in Montevideo, hosted by WHO and the Presidency of Uruguay.

The pledge follows agreement by world leaders to reduce “premature” deaths from NCDs by one-third by 2030 as part of the United Nations’ Agenda for Sustainable Development. Today, NCDs kill 40 million annually, more than any other cause of death. Of these deaths, 15 million occur prematurely among people aged 30-70 years, and 7 million in low- and low-middle income countries.

“It is shocking to see the growing toll that diseases like cancer and diabetes are taking on the people who can least afford healthcare,” said WHO Director-General Dr Tedros Ad-hanom Ghebreyesus.

“Governments must act on pledges to prevent these diseases in the first place, and to en-sure that people can obtain services to treat them,” he added. “Failure do to this imposes massive costs on individuals and communities. It totally contradicts global commitments to sustainable development.”

Right on!

I must say- I do like the Causation Pathway at the introduction of this article (top image). The underlying determinants, I believe, nobody is going to argue about. Neither can the Common Risk Factors be dismissed as illogical- of course they matter most, although my experiences (and those of many others) on what "a healthy diet" is, will be quite different from mainstream thinking. Thereto I certainly also believe hereditary DNA can be switched off and on depending on lifestyle. The Intermediate Risk Factors can also "in general" be accepted, except maybe that the "abnormal blood lipids" bit, which certainly refers to the "good and bad" cholesterol conundrum, which has its roots in Ancel Keys manipulation of data, causing massive Big Pharma activities, using unproven surrogate (and incorrect) hypothesis to be used. Anyway, one can also give a different meaning to "Abnormal Blood Lipids" and will be spot on as to being an important "Intermediate Factor" to prevent premature death from the Killer Disorders.

Summary Common Risk Factors.

Of the stated Common Risk Factors- heridity (non- modifiable as per WHO (?)) will not be discussed any further in Fas´Actions, since I already covered that in the "About me" section as well as the Epigenetics article. Age- of course non-modifiable as per WHO in respect of the number of eclipses around the sun, will be a substantial part of this page in the future, which I will cover in a separate section- Anti-aging- I guess, will certainly include Adult Stem Technology going forward (my absolute specialty)

The remaining three Common Risk Factors, Unhealthy Diet, Alcohol and Tobacco (the latter combo, which I will classify under the heading: Addiction) and physical activity will be covered in detail in the following articles.

Summary Intermediate Risk Factors.

The stated intermediate factors, obesity, blood pressure, glucose serum levels and abnormal lipid profile, I will simply partially re-define as to what, I think, matters most in reversing serious unhealthy conditions and maintaning homeostasis of the body whilst aging healthy and with a good quality of life. The last part, enjoying life and not suffering and being in any pain with mental clarity until the end, must be the objective and goal for folks getting beyond their retirement age.

Related items

As I have stated in the front page introductionary articles of this site, key issues to live a hundred years, I believe, surely has a lot to do with avoiding calamities, or what I called "killer disorders" and adapt the body in such a way, that the cellular composition of the body ages at a reduced speed, maintains homeostasis for as long as possible, with a healthy balance between its main components, fat, water, bone and muscles and stays that way through the right supply of required nutrients, by either proper nutrition or other help and receives sufficient exercise and mobility i.e. avoid sedentary behaviour, to keep all systems functioning properly.

Having stated- or better, repeated those objectives, this would be a good point to return to those "killer disorders" and identify the main causes of death, which should be avoided and which I copied from the WHO (World Health Organization), mentioned in the front page article - link here, that I would use as reference point for my change processes or better, processes to lead to minimalization of all health risks associated with those "killer disorders".

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CYTX is the Nasdaq symbol for Cytori Therapeutics, a struggling SC Company located in San Diego, CA, who´s Management and BOD unfortunately have made many mistakes in realizing the potential of the technology. Fas still believes their fortunes will change dramatically.