Comparison of natural plant and callus extracts of Solanum trilobatum L. was studied against two bacteria and fungi, for their antimicrobial activity using cup diffusion method. Various solvents such as chloroform, petroleum ether and ethanol were used. The leaf and stem segments of the plant were culturedon Murashige and S koog basal medium supplemented with various growth regulators. Maximum callus was recorded on medium containing 0.5 mg/lNAA and 0.5 mgj IKinetin. The results reveals that the stem and leaf callus extracts has shown significant activity against the tested microorganisms than the natural sample.

Protective effect of ethanolic extract of polyherbalformulation (PHF) of three medicinalplants was studied on carbon tetrachloride induced liver damage in rats. Treatment with 250mg I kg b.w. of ethanolic extract of PHF'protected rats against carbon tetrachloride liver injury by significantly lowering 5'NT, GGF, GDH and SDH and bilirubin levels compared to control group of rats. Normalising the effect of these parameters indicates strong hepatoprotective property of the PHF extract.

The benzene, alcoholic and aqueous root extracts (75mg/kg each)of Dalbergia spinosa Roxb were studied for its diuretic activity by using male albino rats by adopting the method of Tipschitz. The alcoholic extract increased the urine volume and electrolytes sodium, potassium and chloride, which is similar to the standard drug Furosemide (100mg/ kg) by inhibiting sodium, potassium, and chloride ion co-transport at thick ascending loop of henle. The present study showed that the alcoholic extract has significant diuretic activity comparable with standard drug Furosemide in producing urinary output and excretion of sodium,potassium and chloride in mEq/ lit/ 6 hrs

Clinical study of the immunoglobululin enhancing effect of "Bala compound" on infants

p. 18

R Appaji Rao, RD Sharma, GP Katiyar, A.J.V. Sai PrasadPMID:22557316

Kaumarbhritya a branch of' Asthanga Ayurveda deals with neonatal, infant and child health care. Multicentric studies conducted in various developed and developing countries have indicated that Infant Mortality Rate (I.M.R.) is very high in developing countries, and infection has been observed as the major cause. Immune system in neonates is not yet fully functional. Bala compound having the ingredients of Atibala(Abutilon indicum Linn), Amalaki(Emblica officinalis Linn), Vidanga(Emblica ribes burn), Guduchi(Tinospora cordifolia WelldMiers), Pippali(Piperlongum linn), Yashtimadhu(Glycyrrhiza glabra Unn ), Shankhapuspi(Convolvulus pluricaulis Chois ), Vacha(Acorus calamus Linn),Musta(Cyperus rotundus Linn ) and Ativisha(Aconitum heterophyllum wall ) are Medhya as well as Rasayana drugs mention in Ayurvedic classics. ' Bala compound' was tried in infants in the form of oral drops for a period of six months and result was assessed for serum immuoglobulins IgG, IgM, IgA for three months of interval of two follow ups (i.e., third and six month of infant) . There is significant increase of immunoglobulins observed after six months administration of 'Bala compoumd'

A Comparative Study of the effect of Vasa Avaleha prepared with Vasa Swarasa and Vasa Kwatha in Tamaka Shwasa

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Ankit Gupta, PK Prajapati, AK ChoudharyPMID:22557317

Vasa (Adhatoda vasica) is used to treat the diseases such as Shwasa, Kasa and Raktapitta in different dosage forms like Swarasa, Avaleha and Ghrita. Although the Avaleha Kalpana is not available in Brihattraya, but Gada Nigraha by Aacharya Sodhal and Bhava Prakasha have described its use in the form of Avaleha to treat the diseases of Respiratory System. The objective of this study is to compare the efficacy of two types of Vasa Avaleha prepared'with either 'Swarasa' or 'Kwatha' of Vasa during their preparation. The outcomes were assessed on the basis of relief in subjective symptoms and certain hematologicalparameters.
Total 35 patients were enrolled for the study. Both the groups showed highly significant results on cardinal symptoms like frequency, intensity and duration of Shwasa (dyspnoea), Kasa (coughing), Peenasa (rhinitis) with maximum percentage in Vasa Avaleha (Swarasa). The formulations also shows a insignificant decrease in haematocrit values which includes Neutrophil, Eosinophil, Lymphocyte count and TL.STL. Overall Vasa Avaleha (Swarasa) shows maximum percentage of improvement than the other group.

Study design: A prospective study of 50 patients suffering from Bhagandara(Fistula in Ano) (age ranging from 18-54years) treated by Kshara sutra therapy
Place: Kshara sutra unit, Central research Unit, Punjabi bagh, New Delhi
Duration: January 2007 to July 2008.
Objectives: To determine the incidence of low or high anal fistula, recurrence rate following Kshara sutra therapy and effect of Ksharasutra therapy on the Bhagandara. Material and methods: The fifty patients (50) were selected randomly in the Out Patient Department.
Study Design: Uncontrolled open level Study.
Results: Patients were followed to see the incidence of recurrence, effect of Kshara Sutra Therapy on incontinence. Overall recurrence rate was only 5.88 %. Minor incontinence was observed only following Kshara sutra Therapy for high variety for which no treatment was given. No such complication occurred in low variety.
Conclusion: Bhagandara (Fistula in Ano) can be treated by Kshara Sutra Therapy with minimal loss of sphincter muscle and low reoccurrence rate.

Pharmacological attributes of indian medicinal plants with special reference to their anti-inflammatory activity

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Galib , BJ Patgiri, PK PrajapatiPMID:22557319

Inflammation has always been a problem of unease to all clinicians and patients since centuries. A total safe and effective drug against inflammation is yet to be emerged in our field which can fulfill the requirements is the need of the hour. Keeping the significance of this in view, clues are being taken from the rich Ayurvedic treasure to find out a safe anti inflammatory drug.

In the context of Bhagna (fractures), Chikitsa sthana of Sushruta Samhita, a classical treatise of Ayurveda the entire protocol for management of different kinds of injuries is elaborated. Manjisthadi Lepa according to the mode of application either Ushna or Sita can facilitate the healing of soft tissue injury like Deep vein thrombosis, Cellutitis, Synovitis and Thrombophlebitis. It is proposed that symptomatic relief can be achieved with Sheeta Lepa in Acute conditions of Abhighata (injury)were Rakta and Pitta are mainly vitiated and UshnaLepa in Chronic conditions were Vata Kapha are vitiated.

The flora of Talakona forest division has been studied for its ethnomedicinal wealth (Hemadri et al, Madhava Chetty et al). These studies have contributed immensely to the rural and forest economy. The present study revealed the medicinal use of 66 species of plants distributedin 40families. Many of the usages were unknown till date. About 65% of the medicinal applications of plants are for internal purposes. Majority of the external formulations are for conditions affecting the integumentary system I'skin. They have been using these parts in the form of paste, powder, juice, decoction, infusion and also in crude form, with other additives like ghee, sesame oil and goat milk, to relieve from different ailments.