Princess Alexia attended the public primary school Bloemcampschool in Wassenaar.[5] Since August 2017 she attends the Christelijk Gymnasium Sorghvliet,[6] an independent Protestant school in The Hague, the Netherlands.[4]

In February 2016, while on a skiing holiday with her family in Austria, Princess Alexia broke her right femur (thigh bone). She was transported via helicopter to a local hospital and had surgery to repair the injury.[8] After a few days in the hospital she was released and required the use of crutches while she healed.[9] Updates on Princess Alexia's condition were posted on the official website of the Dutch monarchy. The accident occurred in the same area as the avalanche which resulted in eventually fatal injuries to her paternal uncle and godfather, Prince Friso, in February 2012.

In free time, she likes horse riding, hockey, singing and playing guitar.