Tag Archives: Tumor

An experimental drug currently being tested against breast and lung cancer shows promise in fighting the brain cancer glioblastoma and prostate cancer, researchers at UT Southwestern Medical Center have found in two preclinical studies.

The drug’s actions, observed in isolated human cells in one trial and in rodents in the other, are especially encouraging because they attacked not only the bulk of the tumor cells but also the rare cancer stem cells that are believed to be responsible for most of a cancer’s growth, said Dr. Jerry Shay, professor of cell biology and a senior co-author of both papers. The Read More…

Researchers at Queen Mary, University of London, studied equivalent cells taken from mouse brains. Principal investigator Silvia Marino, Professor of Neuropathology at Queen Mary, University of London, and her team showed that medulloblastomas can grow from a type of brain stem cell and that these cancers are a distinct form of the disease which may require a completely different approach to treatment.

The key to eradicating tumors and preventing relapses and metastasis is buried within the tumor itself. The tumor cells themselves contain a sort of needle in the haystack. Just 1% of the total volume of the tumor is responsible for reproduction, and a targeted surgery or drugs could be sufficient enough to “deactivate” the tumor and avoid any possibility of a reoccurrence. This type of treatment could possibly change the therapeutic approach to malignant tumors according to an Italian study at the Superior Health Institute (ISS) by Professor Ruggero De Maria, the Director Read More…

What are the biological processes that stem cells go through? What are the industrial processes we need to manufacturing? What do we know about cancer stem cells? How do iPS cells fit into the picture vs. embryonic stem cells? In this episode we investigate how the science and research of stem cells is being translated into industrial cell processes to create FDA approvable, and commercializable products. Differentiation, proliferation, migration, retro-differentiation, trans-differentiation, transformation into cancer cells, the role of tumors‘ micro environments and epigenetics and all reviewed here by the field’s foremost experts.

Research has indicated that certain sarcomas come from the mesenchymal stem cells. However, expression of neural stem cells has been noted in others. Identifying and isolating mesenchymal stem cells and neural stem cells relies on finding specific proteins expressed by both types.

In this study, eight different markers representing proteins associated with these two types of stem cells were applied to the 81 tumors. Through cluster analysis, the researchers organized the data into groups showing similar patterns. Two major subgroups of pediatric sarcomas emerged

news from the world about stem cells

4,743 Shares in Crispr Therapeutics AG (NASDAQ:CRSP) Bought by Cetera Advisor Networks LLC TechNewsObserverCetera Advisor Networks LLC purchased a new position in shares of Crispr Therapeutics AG (NASDAQ:CRSP) in the second quarter, according to the company ...

Crispr Therapeutics (NASDAQ:CRSP) Upgraded by BidaskClub to “Buy” TechNewsObserverCrispr Therapeutics (NASDAQ:CRSP) was upgraded by equities research analysts at BidaskClub from a “hold” rating to a “buy” rating in a research note issued ...

Critical Contrast: Crispr Therapeutics (NASDAQ:CRSP) vs. Mymetics (NASDAQ:MYMX) TechNewsObserverCrispr Therapeutics (NASDAQ:CRSP) and Mymetics (OTCMKTS:MYMX) are both medical companies, but which is the superior stock? We will contrast the two ...

Delivery of crucial protein to brain could help treat rare genetic disorders ScopeStanford scientists have conducted a proof-of-concept experiment in mice that shows they can use blood stem cells to treat a severe brain disease.

Chinese scientists use CRISPR tool on HIV patient for the first time CNNA Chinese team from Peking University have used gene editing tool CRISPR-Cas9 on a HIV patient for the first time. They managed to create stem cells resistant ...

Chinese Scientists Have Tried to Cure HIV with CRISPR Gene Editing: 'The Genie Is out of the Bottle' NewsweekScientists in China have used the CRISPR gene-editing technique to try to cure a man of HIV, in what one expert called an "important step" forwards in treating ...

Research Clears Up Mystery About Most Common Cancer Gene Dana-Farber Cancer InstituteTP53 is the most frequently mutated gene in cancer. Scientists know the “hot spots” on TP53 where mutations are likely to occur, but research into the effect of ...

CRISPR Clinical Trials: A 2019 Update SynBioBetaWith the recent buzz about CRISPR clinical trials, we thought it was time for a comprehensive status update! It can be hard to keep track of all the different trials, ...

Therapeutic Gene Editing for Sickle Cell Disease Technology Networks“It is heartbreaking to see my child go through this crisis. When my son, [Eric*], was five years old, he had a sickle cell crisis and the doctors told me that he might ...

“Special” CRISPR Permits Gene-editing of Stem Cell Derived Neurons Technology NetworksA team of scientists at UC San Francisco and the National Institutes of Health have achieved another CRISPR first, one which may fundamentally alter the way ...

Stem cell therapy may help reduce inflammation and build up healthy cells in the body. Scientists are now investigating whether it may benefit autoimmune conditions such as rheumatoid arthritis. Learn more here.

Doctors have successfully treated an infant with a rare childhood leukemia using a targeted therapy approved for adults with inoperable liver cancer and advanced kidney cancer. The decision to use the drug, sorafenib, was made after pathologists identified a unique mutation of two genes being fused together instead of on separate chromosomes.

Study finds that the diabetes drug metformin, known to promote brain repair, can also help restore cognitive function in adult mice but only in females and in a way that is dependent on the sex hormone estradiol.

Twenty people die waiting for an organ transplant every day in the US, but lab-grown organs so far lack the cellular density, vasculature, and functions required to make them viable replacements. The new SWIFT method solves those problems by 3D printing vascular channel networks directly into living organ building blocks, enabling the creation of larger […]

Healthy cells in our body release nano-sized bubbles that transfer genetic material such as DNA and RNA to other cells. It's your DNA that stores the important information necessary for RNA to produce proteins and make sure they act accordingly. These bubbly extracellular vesicles could become mini treatment transporters, carrying a combination of therapeutic drugs […]

An FDA-approved gene therapy for Leber congenital amaurosis, an inherited vision disorder with a childhood onset and progressive nature, has improved patients' sight. But new research on the blinding condition but new research underscores the importance of further investigation to halt the progression of the disorder.

The obesity epidemic affects nearly half a billion people worldwide, many of them children. Obesity-related diseases including heart disease, stroke, type 2 diabetes, and cancer are a leading cause of preventable death. Researchers have now developed a gene therapy that specifically reduces fat tissue and reverses obesity-related metabolic disease in obese mice.