Hazardous drugs (HDs) are any drugs that may exhibit carcinogenic, teratogenic, developmental, reproductive, or organ toxicity in humans or animals, and include genotoxic drugs or new drugs that mimic existing HDs in structure or toxicity. USP Chapter <800> Hazardous Drugs--Handling in Health Care Settings, which establishes practices and quality standards for handling HDs to promote patient safety, worker safety, and environmental protection, will become official on July 1, 2018. The chapter is comprehensive regarding proper actions related to the receipt, storage, compounding, dispensing, administration, and disposal of sterile and nonsterile HD products and preparations. A simple, common sense approach to preventing the dissemination of and exposure to HDs, as detailed in USP <800>, requires that pharmacy address facility design, monitoring, protective equipment, and personnel practices.

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