Hello,The agencies that monitor pregnancy exposure risks have assured me that topical treatments for skin are almost always safe in pregnancy. The possible exception would be something containing vitamin A such as retin A, but even then it would require very heavy application for a period of time to absorb enough to be a concern. I can't answer for these particular products but the general rule is that these do not cause any increase in risk for birth defects. Keep in mind that about 3-5% of pregnancies do have birth defects from unknown causes. Sometimes things just don't work out right no matter what you do, but these topical treatments should not increase your risk beyond the "normal".