Biosimulation & Modeling - Research

The Biosimulations and Modeling HSRI research cluster aims to accurately simulate dynamic biological processes and physiological behaviors. This requires careful choice of physical and mathematical models.

Often significant computing power is required to capture such a complex environment.

These processes can be modeled at the level of atomic and molecular interactions with quantum mechanical methods (electronic excitation, bond-breaking, adsorption), at the level of atomistic simulations and macromolecular interactions (protein and RNA folding, DNA-binding, protein-RNA interactions, and enzymatic catalysis), at the level of cellular and macroscopic processes (bulk protein distributions in cells, macromolecular synthesis, transport and decay, blood clotting, fluid flow), at level of evolutionary dynamics of macromolecular networks, and at the level of cell, soft tissues, vessels and organ biomechanics.