Interphex 2017, New York

Leading the way in both Liquid and Solid Dosage Processing.
GEA will highlight the ConsiGma™ continuous tableting line; a multipurpose platform that has been designed to transfer powder into coated tablets in development, pilot, clinical and production volumes in a single compact unit.

GEA will be participating in the IPS Technologies Tours during Interphex. These walking show floor tours offer insight into the latest equipment, innovation and manufacturing technologies, and GEA will highlight the ConsiGma™ and Pharma Freeze dryers.

GEA Laboratory homogenizers

World-Class Pharmaceutical Processing Solutions

Successful Tableting

The innovations described in this brochure include a unique technology that independently and simultaneously measures and controls both tablet weight and hardness, and a weight control system that provides increased sensitivity at lower forces. Our presses offer an extended dwell time — up to 300% — resulting in higher outputs and enhanced productivity. And that’s just the tip of the iceberg.

AirConnect™ Flexible small-scale fluid bed processing

The multipurpose AirConnect™ from GEA delivers a range of fluid bed processing solutions for small-scale applications. A service unit provides the main air treatment and control facilities with exchangeable modules delivering an array of processing options, including fluid bed drying, granulation and both pellet and tablet coating.

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GEA proudly presents

GEA Pharmaceutical Freeze Dryers

GEA, a world leader in pharmaceutical freeze drying supply’s a comprehensive range of products and services, pilot plants for research and small-scale production batches, industrial size production freeze dryers as well as complete freeze dryer systems consisting of one or multiple modules plus ALUS™ (Automatic Loading and Unloading System), integrated isolators and CIP-skids. Extending its range GEA offers optimization equipment like LYOPLUS™ a multi-purpose measurement device for pharma freeze dryers help save money and time. LYODATA™ a solution that ensures distinctive marking and complete traceability, including process and product monitoring data.

ConsiGma™ Continuous Tablet Coater

The ConsiGma™ coater is a high speed drum coater, sized and designed to be part of our integrated tableting solution. It can apply decorative and functional coatings using both aqueous and solvent based coating suspensions. The number of drums can be adapted to meet the actual throughput of the line (kg/h). It can also be executed with features which enable wash-off-line (WOL) for extremely fast change-over.

Key characteristics

Plug flow / first-in-first-out principle: The same Consigma™ plug flow philosophy is implemented for the coating process . This allows for a comprehensive and reliable tracing of the product throughout the process.

Short process times of a few minutes. The complete coating cycle requires nominally 6-8 minutes for a 3kg tablet loading.

No scale-up. Same coating wheel is used in R&D and production

Gentle process. The combination of processing small quantities of tablets and the short process times makes the equipment suitable for coating very soft tablets.

On display at the show also the following process technology components

MOBILE MINOR™

Lab-scale Spray Dryer - small quantities of solutions, suspensions or emulsions can be dried into representative powder samples, facilitating the retrieval of the process data required for scaling-up to industrial production.

AirConnect - modular fluidized bed technologies

The AirConnect™ is the ultimate fluid bed processor for small-scale research and production applications (from 100 g up to more than 10 kg). Suitable for granulating, drying and coating, the AirConnect™ has the capability to accelerate and optimize product development by minimizing the amount of scale-up operations required to move from R&D-level batch processing to full-scale production systems.

A key feature is the ability to remove both the product container and the filter housing from the main service unit, enabling a wide range of processing capacities. Taking a modular approach allows the integration of other airflow-based processes such as the Precision-Coater™ , a system can be used to enhance pellet coating; and the ConsiGma™ tablet film-coating module that can be integrated with the standard filter housing.

PandaPlus - table-top laboratory high pressure homogenizer

High pressure homogenization reduces the particle size of liquid pharmaceutical products to make a dispersion of active ingredients more stable for enhanced clinical effectiveness. Optimised particle micronization and homogenous distribution means that API bioavailability and drug tolerance is improved. PandaPLUS is the unique on the market able to operate at any pressure up to 2000 bar on minimal sample volume so is ideal for the treatment of nanoparticles, nanodispersions, nanoemulsions, cell disruption, but can also be used successfully for processing dairy and liquid food products.

PandaPLUS is the perfect solution to verify the homogenization effects and guarantee scalability of results from lab testing to industrial production. From the initial concept, through pilot trials and final analysis: this is the right way to fine tune the perfect product’s formulation and the best homogenizing condition.

Leading the way in both Liquid and Solid Dosage Processing.
GEA will highlight the ConsiGma™ continuous tableting line; a multipurpose platform that has been designed to transfer powder into coated tablets in development, pilot, clinical and production volumes in a single compact unit.

GEA will be participating in the IPS Technologies Tours during Interphex. These walking show floor tours offer insight into the latest equipment, innovation and manufacturing technologies, and GEA will highlight the ConsiGma™ and Pharma Freeze dryers.

Working with GEA Service means partnering with a dedicated team of service experts. Our focus is to build, maintain, and improve customer performance throughout the entire life cycle of the plant or farm and its equipment.

Beginning of Life Services ‒ Getting you started with seamless support for instant productivity and performance

Lifetime Services ‒ Keeping it running with the cost-efficient way of ensuring peak safety and reliability