Signaling from dysfunctional mitochondria induces a distinct type of senescence

Researchers need to stop thinking of cellular senescence, now accepted as an important driver of aging, as a single phenotype stemming from genotoxic stress. Research reveals that signaling from dysfunctional mitochondria also induces senescence -- and that the senescent cells secrete a distinctly different 'stew' of biologically active factors in a process unrelated to the damaging free radicals that are created in mitochondria as part of oxygen metabolism.
Source: Medicine Science Daily