A student of Isaac Newton, John Selden believes he can turn his daughter into a brilliant natural philosopher and alchemist. Secluded in their ancient house, with only two servants for company, he fills Emilie with knowledge and records her progress obsessively. In the spring of 1725, their work is interrupted by the arrival of two strangers: one a researcher, the other a dazzling young merchant. During the course of a sultry August, while her father is away, Emilie experiences the passion of first love. Listening to her heart rather than her head, she makes a choice. Banished to London and plunged headlong into a society that is both glamorous and ruthless, Emilie discovers that for all her extraordinary education she has no insight into the workings of the human heart. When she tries to return to the world of books and study, she instead unravels a shocking secret that sets her on her true journey to enlightenment