Selznick leased offices at the studio during the first year or so and at the beginning of 1937 Selznick International Pictures took over the entire lot. The SIP name went up over the entrance of the historic Southern Plantation style administration building and that view of the front of the building became the iconic studio logo seen at the beginning of SIP films. Even though the studio reverted to RKO in the 1940s, Selznick kept offices there for the rest of his life.

Selznick raised the initial funding of US$400,000 in Los Angeles, with half of that amount coming from his brother Myron Selznick, a Hollywood agent, and the other half from MGM production chief Irving Thalberg and his wife actress Norma Shearer.[1] He raised an additional $300,000 from "small" investors in New York, and then the final $2.4 million from Jock Whitney and his family. Whitney himself became chairman of the board, and Selznick president, of the new company.

Because Whitney and his cousin Cornelius Vanderbilt Whitney also owned Pioneer Pictures, an independent studio they formed in 1933 on facilities rented at the RKO studios, Pioneer was informally merged with Selznick International Pictures in 1936. Selznick International assumed Pioneer's contract to make at least six pictures in the new full-color Technicolor process, of which the Whitneys owned a 15 percent share.[2]

Selznick intended to produce a few features each year, a plan which he hoped would allow him to be as picky and careful as he liked and to create the best films possible. He said to his company's board in 1935, "There are only two kinds of merchandise that can be made profitably in this business, either the very cheap pictures or the very expensive pictures." Selznick believed, "there is no alternative open to us but to attempt to compete with the very best."[3]

By 1940, Selznick International Pictures was the top-grossing film studio in Hollywood, but without a major studio set-up in which to re-invest his profits, Selznick faced enormous tax problems. That year, to draw down their profits as capital gains, he and the other owners made an agreement with the Internal Revenue Service to liquidate Selznick International within three years, which they did by dividing and selling to each other the company's assets. Jock Whitney and his sister Joan Whitney Payson acquired Gone with the Wind, which they resold at a substantial profit to Metro-Goldwyn-Mayer in 1944.[4][5][6] At the time of the final dissolution in 1943, three features were in production or pre-production, although they were released in 1944 and 1945.

To complete his obligation to deliver two more pictures to United Artists, Selznick formed David O. Selznick Productions in 1940 at the same studio location. The new company also took over the old company's contracts with individual directors and actors.[7]

After the dissolution of Selznick International, Selznick established Vanguard Films, Inc. in 1943 and Selznick Releasing Organization in 1946.[8] Vanguard was created to continue his productions, while Selznick Releasing was made to distribute output by Vanguard. Previously, Vanguard released through United Artists, of which Vanguard owned one-third of its stock. As with Selznick International, Vanguard was located at the RKO studio.

The rights to the Selznick library have been scattered, as noted in the following timeline.

1943: Jock Whitney sold to Film Classics, Inc. the rights to A Star Is Born and Nothing Sacred (both of which were actually owned by Pioneer Pictures), and the Selznick International productions Little Lord Fauntleroy, Made for Each Other, and The Young in Heart.[9]

David O. Selznick retained ownership of The Garden of Allah, The Prisoner of Zenda, The Adventures of Tom Sawyer, Intermezzo, and Rebecca after the liquidation of Selznick International Pictures.[14] Most of the Selznick films are now owned by ABC (via Walt Disney Studios Motion Pictures). The notable exception is Gone with the Wind, which Jock Whitney and his sister sold to MGM in 1944, which was subsequently acquired by Turner Entertainment, with distribution by Warner Bros. The films A Star Is Born, Little Lord Fauntleroy, Nothing Sacred, and Made for Each Other are now in the public domain in the United States, with original film negatives to the latter three films owned by Disney[15] and the former's owned by Warner Bros.

The Selznick International logo theme is introduced with this film, written by Alfred Newman, who composed the score for Zenda. The theme would be used to open every film made by the studio after this.