The core problem addressed in the current thesis is to provide a novel test bed
for depth map generation and stereo image-based algorithms. The test bed comprises
of elements such as (i) the choice and calibration of ...

The recent development of high-throughput genomics techniques and their subsequent applications have completely transformed the study of biology. The analysis, interpretation and storage of the resulting large volumes of ...

DNA in Eukaryotic cells is complexed with histone proteins to form chromatin. This mediates DNA packaging into the nucleus but also facilitates the regulation of all DNA-templated processes, including transcription, ...

Multiple sclerosis (MS) is characterised by the presence of inflammatory demyelinating foci throughout the brain and spinal cord, accompanied by axonal and neuronal damage. Although inflammatory processes are thought to ...

The DNA damage response (DDR) is a signal transduction cascade, which regulates cell cycle progression, gene transcription and DNA repair. Histones also play a vital role in the activation of the DDR and have been shown ...

This thesis is concerned with classification problems for finite linear groups. Our main concern is with groups of prime degree, and groups defined over finite fields and fields of zero characteristic. We use the computational ...

The balloon catheters produced by Boston Scientific are manufactured using a laser bonding process. The behaviour of the materials during this laser welding process is not very well understood. In this work a computational ...

The lithostratigraphy and fauna of Carboniferous sedimentary sequences in northwest and southwest Ireland were investigated to reconstruct how and why palaeoenvironments were changing throughout the upper Viséan and ...

An experimental and computational investigation of cortical bone failure mechanisms has been conducted in this thesis. Firstly, a computational comparison of four methods of proximal humeral fracture fixation was conducted. ...

In many situations it is of primary interest to estimate the rate of change of the relationship between response and explanatory variables. In this thesis derivative estimation using spline smoothing is explored. A review ...

Functional ability describes a person's capability to perform those tasks that
are necessary to live independently. It is a proven predictor of functional decline,
the need for hospitalisation and institutionalisation ...

Tidal current energy resources have the potential to provide a sizable proportion of our future energy requirements. However, significant questions still exist on the impacts of tidal turbines on the hydrodynamic environment. ...

This project investigated the therapeutic potential of allo-antigen specific regulatory
T-cells in the context of penetrating keratoplasty. Two methods of ex-vivo generation
of T regulatory cells have been explored in ...

Survival trees are a non-parametric modeling strategy that can be included in the area of statistical modeling. These type of models can be used as an alternative to Cox proportional hazards models for the analysis of ...

The late-Caledonian granites of south Connemara occupy a key location in the western Irish Caledonides. The granites comprise the Galway Granite Batholith and its satellite plutons of Roundstone, Inish, Omey and Letterfrack. ...

In the past few decades, microRNAs emerged as key regulators of gene expression in many fundamental biological processes such as development and differentiation as well as diseases. There are thousands of microRNAs that ...

It has been shown that the graph topology can influence the level of cooperation in evolutionary games. Previous research showed that graphs like scale-free networks and small-world networks are more useful in maintaining ...

Abstract
Pain represents a major unmet clinical need and affects a large number of individuals worldwide. The modulation of pain by cognitive and emotional factors is now widely recognised. Increased understanding of the ...

Channelling is an undesirable phenomenon in the fixed-bed combustion of biomass. It is characterised by an uneven air distribution, and thus fuel conversion, throughout the fuel bed. Attempts to mitigate the channelling ...

This research considers the problem of using miniature low-cost robots for real-world tasks. The issues of low quality sensor data, inaccurate odometry, low processing capacity and limited power are approached through the ...