Falconieri Visuals

Improving Resolution by Cryo-EM: ß-galactosidase

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A Spitting Image in 3D

Glutamate Receptor Gating Cycle

This molecule, beta-galactosidase, has been studied by the structural biology technique cryo-electron microscopy (cryoEM) in order to determine its structure. As cryo-EM technology has improved, the resolution of the resulting structures has improved from rough, low resolution maps (blue, left) to high resolution maps that enable model fitting (gold, right).
Cryo-electron microscopy received the 2017 Nobel Prize in Chemistry.

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