Many faculty want to expose
their students to the concept of DNA microarrays, either as a quick exposure
early in the curriculum, or later in the curriculum combined with real data
analysis. Furthermore, high school teachers increasingly want to bring genomics
into their curricula. They want their students to understand differential
gene, how math is important for analyzing biological data, and how DNA microarrays
can be used for diagnosis.

For all these reasons, we wanted
to develop a very innexpensive DNA microarray simulation that does not use
any DNA at all. With this procedure, students can "print" their
own microarrays and generate signal within one class period. The only lab
equipment you need is some hot water to melt the "target DNA".
Directions for a home-made version are posted below. Genisphere has improved
the original design and produced a kit that works very well and contains
everything you need to get started.

These DNA microarrays simulations
have been field tested in high schools in Illinois and Maryland. Studnets
showed learning gains and attitudinal improvements. We have developed a curricular
materials that help teachers match their course lesssons to the national
science standards. We also have developed assessment tools so you can assess
the impact of the materials.

Colors can fade when exposed
to light, though the commerical kit has improved staying power.