"Nuclear Targeting of an Endosomal Membrane E3 Ubiquitin"

Dr. Erickson is a Professor of Biochemistry and Biophysics in our department. Her research focuses on characterizing the structural signals that are responsible for moving enzymes normally stored intracellularly in lysosomes into the extracellular environment, where they may serve physiological functions not normally ascribed to lysosomal proteases. Four proteins that potentially bind a lysosomal protease precursor in multivesicular endosomes, an endosome which can be induced to secrete its contents in specialized cells, are being characterized.