Purpose: 1) Assess reasons for refusal to participate and for dropping out before intake interview from an ongoing CAM trial of reflexology; and 2) Investigate the utility of demographics, disease characteristics, and Palliative Prognostic Score (PPS) as predictors of early dropout from the trial following consent. Conceptual Framework: The Wyatt Quality of Life Model provides the conceptual framework for the CAM trial. Subjects: Eligible women had a diagnosis of advanced breast cancer, were on chemotherapy, and had a PPS of 11 or less (i.e., a 30 day survival probability of less than or equal to 70%). Methods: Eligible women (N=326) were approached at 12 Midwestern cancer centers. Refusal reasons were obtained for N=91 women. Twenty-five women dropped out before the intake interview; 210 completed the intake interview. Medical records data included demographics, cancer recurrence and metastasis, and the PPS. Differences between groups were using t-tests and Fisher's exact tests. Results: Fewer than 10% of the women who refused to participate gave the reasons of being "too sick" or "overwhelmed". "Disinterest in research," was the most frequent refusal reason. Among 25 early dropouts, 28% were Black women as compared to 9.7% of Black women among those who completed the intake interview (p=.03). Among early dropouts, 64% had metastasis; among those who completed the intake interview, 73.9% had metastasis (p=.10). Cancer recurrence, age, and the PPS were not predictive of early retention. Conclusions: Women with advanced disease were likely to enter and remain in the trial despite deteriorating health. Using the PPS as part of inclusion criteria was not effective in improving retention. Acknowledgement of Funding: NCI 1RO1CA104883-01A1

Full metadata record

Recruitment and Early Retention of Women with Advanced Breast Cancer in a Complementary and Alternative Medicine (CAM) Trial

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dc.identifier.uri

http://hdl.handle.net/10755/159974

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dc.description.abstract

<table><tr><td colspan="2" class="item-title">Recruitment and Early Retention of Women with Advanced Breast Cancer in a Complementary and Alternative Medicine (CAM) Trial</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Midwest Nursing Research Society</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2009</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Adams, Lora, MSN</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">Michigan State University</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">College of Nursing</td></tr><tr class="item-address"><td class="label">Contact Address:</td><td class="value">E515 West Fee Hall, East Lansing, MI, 48824, USA</td></tr><tr class="item-phone"><td class="label">Contact Telephone:</td><td class="value">5178622388</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">adamslo1@msu.edu</td></tr><tr class="item-co-authors"><td class="label">Co-Authors:</td><td class="value">L. Adams, G.K. Wyatt, A. Siddiqi, College of Nursing, Michigan State University, East Lansing, MI; A. Sikorskii, Department of Statistics and Probability, Michigan State University, East Lansing, MI;</td></tr><tr><td colspan="2" class="item-abstract">Purpose: 1) Assess reasons for refusal to participate and for dropping out before intake interview from an ongoing CAM trial of reflexology; and 2) Investigate the utility of demographics, disease characteristics, and Palliative Prognostic Score (PPS) as predictors of early dropout from the trial following consent. Conceptual Framework: The Wyatt Quality of Life Model provides the conceptual framework for the CAM trial. Subjects: Eligible women had a diagnosis of advanced breast cancer, were on chemotherapy, and had a PPS of 11 or less (i.e., a 30 day survival probability of less than or equal to 70%). Methods: Eligible women (N=326) were approached at 12 Midwestern cancer centers. Refusal reasons were obtained for N=91 women. Twenty-five women dropped out before the intake interview; 210 completed the intake interview. Medical records data included demographics, cancer recurrence and metastasis, and the PPS. Differences between groups were using t-tests and Fisher's exact tests. Results: Fewer than 10% of the women who refused to participate gave the reasons of being &quot;too sick&quot; or &quot;overwhelmed&quot;. &quot;Disinterest in research,&quot; was the most frequent refusal reason. Among 25 early dropouts, 28% were Black women as compared to 9.7% of Black women among those who completed the intake interview (p=.03). Among early dropouts, 64% had metastasis; among those who completed the intake interview, 73.9% had metastasis (p=.10). Cancer recurrence, age, and the PPS were not predictive of early retention. Conclusions: Women with advanced disease were likely to enter and remain in the trial despite deteriorating health. Using the PPS as part of inclusion criteria was not effective in improving retention. Acknowledgement of Funding: NCI 1RO1CA104883-01A1</td></tr></table>

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dc.date.available

2011-10-26T22:30:29Z

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dc.date.issued

2011-10-17

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dc.date.accessioned

2011-10-26T22:30:29Z

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dc.description.sponsorship

Midwest Nursing Research Society

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