FILE: The FDA has approved a new drug for the maintenance and treatment of pancreatic cancer. (Prescription pills in a yellow bottle over a wooden table with selective depth of field. (Photo by Roberto Machado Noa/LightRocket via Getty Images))

The coronavirus quarantine has contributed to a surge in the demand for prescription tranquilizers and sleep aids in the United States, as Americans continue to feel on edge about the uncertainty of the disease, according to a new research report.

The largest spike was in prescriptions for anti-anxiety drugs, which rose 34.1 percent from mid-February to mid-March, per the pharmacy benefit management organization Express Scripts.

From February 16 to March 15, prescriptions for antidepressants rose 18.6 percent, while sleeping medications ticked up by 14.8 percent.

"This analysis, showing that many Americans are turning to medications for relief, demonstrates the serious impact COVID-19 may be having on our nation’s mental health," Express Scripts said.