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Development of methods for the assessment of the health effects from mixtures of food additives

Project Code: T01040/41

21/08/2009

TNO BIBRA International Ltd.Groten, J ; Stierum, R

T01040 & T01041 aimed to develop methods to assess the health effects of mixtures of food additives, each of which is known to produce liver effects in animal studies. The additives chosen were: butylated hydroxytoluene (E321), curcumin (E100), propyl gallate (E310) and thiabendazole (E233). They were tested both individually and in various statistically determined combinations, to ascertain whether there were any interactions between the chemicals. These projects were a continuation of previous work performed in the FSA funded Project T01021.