Cilic's early exit opens up Federer's path to the final even more, with No. 8 Kevin Anderson the highest-seeded player left in the Swiss star's half of the draw after No. 6 Grigor Dimitrov lost in the first round.

"Yesterday he was playing so, so good, and hitting the ball so hard that I couldn't do anything," the 82nd-ranked Pella said. "So the rain helped me a lot."

Cilic was runner-up to Roger Federer last year and showed great form by beating Novak Djokovic in the Queen's Club final last month.

His early exit opens up Federer's path to the final even more, with No. 8 Kevin Anderson the highest-seeded player left in the Swiss star's half of the draw after No. 6 Grigor Dimitrov lost in the first round.

Stan Wawrinka also exited, losing to Italian qualifier Thomas Fabbiano 7-6 (7), 6-3, 7-6 (6). That match was also suspended on Wednesday with Wawrinka leading 6-5 in the third set, but Fabbiano wrapped up the victory quickly to equal his best Grand Slam result by reaching the third round.

Wawrinka, whose ranking has fallen to 224th following knee surgery, came from a set down to upset sixth-seeded Grigor Dimitrov in the first round for just his second Grand Slam victory since last year's Wimbledon.

Former champions Novak Djokovic and Rafael Nadal remained on course for a semifinal meeting.

Djokovic called for a trainer and had his left leg massaged when leading 4-3 in the third set. But he easily held serve in the next game and broke Zeballos again to close out the match.

Nadal won only 64 percent of points on his first serve and faced 13 break points — including three in the first game of the match — but he saved 11 of them and converted five of his own to wrap up the win in under 2 1/2 hours on Centre Court.

The 11-time French Open champion is looking for his third title at the All England Club and first since 2010.

Ninth-seeded John Isner hit 64 aces and saved two match points to beat Ruben Bemelmans 6-1, 6-4, 6-7 (6), 6-7 (3), 7-5 in a match that was also suspended overnight.

Isner's ace total was the third-highest ever at Wimbledon — behind his own record in a three-day epic against Nicolas Mahut in 2010, the longest tennis match in history. Isner had 113 aces in that match and Mahut hit 103.

Isner faced two match points against Bemelmans at 5-4 in the fifth set but held and then broke in the next game.

He was given a code violation in the fourth-set tiebreaker on Wednesday after losing his cool following a video review that went against him.