Billed as one of the games of the tournament prior to kick-off, Latin American giants Mexico and Uruguay did not disappoint in Glendale, Arizona. Mexico got off to the perfect start when former Leverkusen midfielder Andres Guardado's cross was turned into his own net by Uruguay defender Alvaro Pereira, after Chicharito's clever run had created space in the six-yard box. Mexico continued to dominate the first half, enjoying 71 per cent possession, but failed to add to their lead before the break.

El Tri went into the second period with a man extra after Matias Vecino was sent off for Uruguay, and they looked increasingly comfortable was the game wore on. However, after Guardado was given his marching orders for a second bookable offence, Uruguay pulled level through a Diego Godin header. The game appeared to be heading for a draw until Mexico captain Rafael Marquez netted a late second, and Hector Herrera put the icing on the cake with a third to put EL Tri in pole position to top Group C and advance to the knockout stages.