The Red Devils were disappointing in a 1-1 draw with Wolves in the Premier League on Saturday, and Jose Mourino is certain to make plenty of changes here.

The Carabao Cup is usually used as a chance to field fringe players, particularly in the earlier rounds, and Mourinho will be hoping some lesser lights step up as he welcomes Frank Lampard to Old Trafford.

The Derby manager enjoyed great success playing under Mourinho at Chelsea, and it will be fascinating to see how he attempts to counter the Portuguese boss’s tactics.

Sergio Romero is in line to make his first appearance of the season, with the Argentina goalkeeper fit again after a knee injury ruled him out of the World Cup and the opening weeks of the campaign.

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Alexis Sanchez might start again(Pic: GETTY)

Meanwhile, Marcus Rashford serves the third game of his suspension for a red card at Burnley earlier this month.

Ander Herrera (ankle) and Marcos Rojo (knee) are unlikely to feature as they recovery from injury, but Nemanja Matic could start after missing the Wolves draw with a one-match ban for his sending off at Watford.

Phil Jones may also return to the defence after suffering a hamstring injury in the defeat to Tottenham last month, while Mourinho has confirmed Diogo Dalot will make a home debut after impressing away to Young Boys in the Champions League last week.

While most of the team is set to change from Saturday’s game, one of Romelu Lukaku, Alexis Sanchez and Jesse Lingard is likely to retain a place in attack due to Rashford’s suspension.