Republican National Committee Chairman Reince Priebus became the first official to call on Weiner to resign after Weiner's mea culpa press conference on Monday.

"Congressman Weiner's actions and deception are unacceptable and he should resign. We do not need an investigation to know he lied and acted inappropriately, we need a resignation," Priebus said in a written statement.

"Either Leader Pelosi and DNC Chair Wasserman Schultz believe members of Congress are held to a different set of standards or they believe these actions demand his resignation," he added.

After Pelosi's quick call for an ethics committee investigation, Weiner's fellow Democrats seem to be fleeing for the sidelines.

"I know Congressman Weiner. And I wish there was some way I could defend him -- but I can't," Senator Harry Reid, D – Nev., said. Reid added that if Weiner called him for advice, he'd tell him to "call someone else."

Although Weiner's actions would be considered by many to be lewd and inappropriate, the major question for the ethics committee is whether he broke the rules of the House of Representatives.

Blake Chisam, former staff director of the ethics committee, says that if Weiner used his government computer to send the messages, he could be in trouble, even though some incidental personal use is permitted.

"You know the rules in the house can often be a labyrinth," Chisam told ABC News, adding that the questions of whether sending pornography or lewd photographs will be difficult to argue as "incidental."

Adding to the carnival-like atmosphere surrounding the story, Donald Trump posted a scathing Youtube video with his reaction to the scandal.

"The fact is, Anthony Weiner is a bad guy. He's a psycho. And when this came out, I was not surprised at all," Trump said in the clip.