Winchester has also appeared in the films In My Sleep (as the lead),[1] and Solomon Kane (as a former member of the title character's crew, turned freedom-fighter) and the Syfy TV mini-series Alice.

From 2010, he has played the role of Frank Stanton in the Fox TV series Fringe. From 2011, he has appeared as Leontes in the Starz series Camelot. Other credits include the second, third and fourth seasons of Strike Back, which aired on Sky1 in the UK and Cinemax in the US. The series follows the adventures of two Section 20 agents, Sgt. Michael Stonebridge (Winchester) and American former Delta Force officer Damien Scott (Sullivan Stapleton).