Reactogenicity and immunogenicity of a live attenuated tetravalent measles-mumps-rubella-varicella (MMRV) vaccine

Terry NolanThe University of Melbourne, Department of Paediatrics, and Murdoch Children s Research Institute at the Royal Children s Hospital, Melbourne, AustraliaVaccine 21:281-9. 2002

..This tetravalent MMRV candidate vaccine showed promising results, although further examination of the possible increase in minor fever and decreased varicella immunogenicity should be assessed in future studies...

Transmission of varicella vaccine virus to a non-family member in China

..While varicella incidence would be expected to decrease, mathematical models predict an initial increase in herpes zoster incidence if re-exposure to varicella protects against reactivation of the varicella zoster virus...

Herpes zoster with skin lesions and meningitis caused by 2 different genotypes of the Oka varicella-zoster virus vaccine

..Since then, vaccination coverage has increased substantially. We updated the analysis of US varicella mortality for 2002-2007 and assessed the impact of the first 12 years of the US varicella vaccination program on varicella deaths...

Economic evaluations of varicella vaccination programmes: a review of the literature

Nancy ThiryDepartment of Epidemiology and Social Medicine, Centre for the Evaluation of Vaccination, University of Antwerp, Antwerp, BelgiumPharmacoeconomics 21:13-38. 2003

..Since violation of these assumptions could have important adverse public health effects, we suggest pre-adolescent vaccination as a more secure alternative. This option deserves more attention in future analyses...

Safety profile of live varicella virus vaccine (Oka/Merck): five-year results of the European Varicella Zoster Virus Identification Program (EU VZVIP)

..Unvaccinated children with a previous history of varicella may have greater sensitivity to exogenous exposures (boosting) and a poorer cell-mediated response following primary infection relative to older age groups...

..Waning might also be an issue with the newly recommended two dose vaccination schedule. Sustained surveillance for varicella outbreaks in populations with varicella immunization programs therefore is mandatory...

Chickenpox and pneumonia following varicella vaccine

Ghan Shyam LohiyaInfect Control Hosp Epidemiol 25:530. 2004

Recurrent papular urticaria after varicella immunization in a fifteen-month-old girl

David E BronsteinDepartment of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, CA, USAPediatr Infect Dis J 24:269-70. 2005

..We describe a 15-month-old girl who experienced the onset of recurring papular urticaria after varicella immunization. The rash was varicella-like and thought by us to be caused by vaccine virus...

..Adding a 2-dose program may help guarantee high population-level effectiveness against varicella. However, the incremental benefit of a second dose is highly dependant on the effectiveness of the first dose and its impact on zoster...

[Incidence of herpes zoster in pediatricians and history of reexposure to varicella-zoster virus in patients with herpes zoster]

..Publicly funded routine immunization programs at 12 or 15 months of age were introduced by 5 provinces and territories (prov/terr) in 2000 to 2002 (earlier programs, EP) and by 8 prov/terr in 2004 to 2007 (later programs, LP)...

Varicella vaccine--are two doses better than one?

Anne A GershonN Engl J Med 347:1962-3. 2002

The safety and immunogenicity of a quadrivalent measles, mumps, rubella and varicella vaccine in healthy children: a study of manufacturing consistency and persistence of antibody

..The true burden of varicella complications in Germany is not known. We investigated the incidence and pattern of varicella complications in children and adolescents using 3 independent surveillance sources...

Complications of varicella requiring hospitalisation before and after the introduction of varicella vaccine in a children's hospital in Taiwan

..The evaluation of a program of vaccination of 12-month-old children, with and without a catch-up program for susceptible 12-year-olds, is presented here...

Varicella: epidemiological aspects and vaccination coverage in the Veneto Region

Vincenzo BaldoDepartment of Environmental Medicine and Public Health, Institute of Hygiene, University of Padua, Padua, ItalyBMC Infect Dis 9:150. 2009

..To evaluate parameters at the start of the programme, we conducted a study to describe the epidemiology of varicella infection and coverage rates for varicella vaccine in the Veneto Region (North-East Italy)...

The effect of vaccination on the epidemiology of varicella zoster virus

..To present an up-to-date review of studies investigating the efficacy, adverse events and vaccination regimens of the varicella vaccine and the new presentation combined with the vaccine for measles, mumps and rubella...

..In summary, varicella immunization induced long-term humoral and cellular immunity, and initial differences between cell-mediated responses in children and adults diminished over time...

Identification of CD8+ T cell epitopes in the immediate early 62 protein (IE62) of varicella-zoster virus, and evaluation of frequency of CD8+ T cell response to IE62, by use of IE62 peptides after varicella vaccination

..Varicella vaccination of 3 VZV-immune subjects was associated with increases in IE62 peptide-specific CD8(+) T cells, a finding indicating that in vivo re-exposure boosts memory immunity to this important viral protein...

An outbreak of varicella in elementary school children with two-dose varicella vaccine recipients--Arkansas, 2006

..In October 2006, the Arkansas Department of Health was notified of a varicella outbreak among students where some received a second dose during an outbreak-related vaccination campaign in February 2006...

An elementary school outbreak of varicella attributed to vaccine failure: policy implications

..Given the overlap in MMR and varicella vaccination schedules, development of a combined vaccine appears logical and would facilitate the introduction of 2 doses of varicella vaccination in healthy children with no additional injections...

..We have competent, outstanding staff whose aim is not only to provide compassionate medical care to HIV-infected patients but also to perform meaningful and useful research on prevention and treatment of HIV infection. ..

..Ultimately, the Yale CRS Program will help to increase the pool of physician-investigators who will be uniquely poised to conduct research to directly improve the health of all Americans. [unreadable] [unreadable] [unreadable]..

..In addition to assessing possible methodologies for the larger project, the preliminary study is designed to yield standalone results with important implications. [unreadable] [unreadable] [unreadable]..

..Teens who do not involve their parents may take longer to obtain an abortion either out of state or through a judicial bypass. Thus, we expect PI laws to increase the rate of second trimester abortions among minors. ..