Queen Sofía Spanish Institute, an American non-profit organization at 684 Park Ave., is about to go on the market for $48 million, Gimme Shelter has learned.

The stunning, landmarked Neo-Federal townhouse was designed by McKim, Mead & White — the legendary architectural firm that built the original Penn Station. This mansion was built in 1927 as a residence for Oliver D. Filley, the son-in-law of Percy R. Pyne. Margaret Rockefeller Strong — the granddaughter of Standard Oil co-founder John D. Rockefeller — later bought this and eventually donated it to the institute in 1965.

The Queen Sofía Spanish Institute’s purpose, according to its website, is “to promote greater awareness and understanding of the culture of the Spanish-speaking world in the United States.” The institute, however, is no longer offering Spanish language classes and shut down programming.

A new buyer might want to return it to its single family mansion status though its proximity to Hunter College might be an issue, our spies say.