This study is a research and development aimed at developing multimedia interactive learning based animation as an effort to improve student learning motivation in learning Fashion Design Technology, apart from this study also aims to design a learning program courses Fashion Design Technology with a focus on optimizing the use of interactive media in learning process. From this study showed: 1) A preliminary study found that, the problems faced by students when studying Fashion Design Technology is: the student is not optimal when learning designing clothes based computer technology both in terms of learning content, learning mechanisms that still uses a linear media, and limitations of highly structured learning time. 2) Animation multimedia has the following characteristics: a media of learning is convergent, interactive, self-contained in the sense of giving convenience to users without the guidance of others, as multimedia applications can present the material to see more interesting and informative. 3) Design of multimedia learning software developed include: the creation of flowcharts, storyboards and drafting manuscript of interactive multimedia based animation. 4) Based on the results of validation by multimedia experts obtained an average percentage of 85.55% viability, of the material experts obtained an average percentage of 90.84% viability and by students as users gained an average percentage of 96.38% eligibility , so it can be said that the standard of the feasibility of interactive multimedia based animation developed is included in the category of Very High or Very Good. Furthermore, experts agree that the development of interactive multimedia based animation on learning Fashion Design Technology can be used with some aspects that need to be improved to obtain higher levels of feasibility / more optimal.