EndNote is a software to maintain the research work. It is the best tool for publishing and managing bibliographies, citations, and references on Windows and Macintosh desktop. It is not merely a standard reference manager. It moves through the research process as the user search, organize, write, publish and share his research work. Tap into hundreds of online databases and instantly find what you are looking for. It automatically downloads and attaches for free, online full-text PDFS to the saved references. EndNote provides the user with a window having a drop-down menu to choose the kind of reference they need, and fields ranging from the common to those specific to the type of reference. There are some databases (e.g. PubMed) in which the user requires to select citations, select a peculiar format, and save them as .txt files. Hence, the user is allowed to import the citations into the EndNote utility. It also useful to search storage catalogs and free databases such as PubMed from within the EndNote application searches itself.