IT IS PROPOSED THAT THIS FILING WILL BECOME EFFECTIVE (CHECK APPROPRIATE BOX)

x

IMMEDIATELY UPON FILING PURSUANT TO PARAGRAPH (B) OF RULE 485.

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ON [DATE] PURSUANT TO PARAGRAPH (B) OF RULE 485.

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60 DAYS AFTER FILING PURSUANT TO PARAGRAPH (A)(1) OF RULE 485.

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ON [DATE] PURSUANT TO PARAGRAPH (A) OF RULE 485.

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75 DAYS AFTER FILING PURSUANT TO PARAGRAPH (A)(2) OF RULE 485.

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ON [DATE] PURSUANT TO PARAGRAPH (A)(2) OF RULE 485.

EXPLANATORY NOTE

This filing relates to the following series of the Registrant:

Guggenheim ABC High Dividend ETF

Guggenheim Airline ETF

Guggenheim China All-Cap ETF

Guggenheim China Technology ETF

Guggenheim S&P Global Water Index ETF

Guggenheim Solar ETF

2

SIGNATURES

Pursuant to the requirements of the Securities Act of 1933 and the Investment Company Act of 1940, the Registrant certifies that it meets all the requirements for effectiveness pursuant to Rule 485(b) under the Securities Act of 1933 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Lisle and State of Illinois on the 22nd day of January, 2013.

CLAYMORE EXCHANGE-TRADED FUND TRUST 2

By: /s/ Donald C. Cacciapaglia

Donald C. Cacciapaglia

Chief Executive Officer

Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed below by the following persons in the capacities and on the date indicated.