When flying in any sim, you ought to get the controls as close as possible to what you'll be using in real life. FS One makes a big deal out of reassigning any channels that you don't have to the keyboard. But then what will happen when you're out of control, near crash, and your instinctive muscle-memory tells you to reach for the keyboard to autorotate (just for example?)

If I'm flying anything more than a 4-channel foamy, I always want to plug my real Tx in to the sim... keep it real!