Acromegaly

Acromegaly is a rare disease caused by overproduction of growth hormone by the pituitary gland, often because of a tumor. The condition may progress slowly for many years, gradually changing the person's appearance, particularly the hands and face. Some adults with acromegaly also grow taller. It is generally not an inherited condition. Wikipedia

Pseudoacromegaly (with the physical changes in appearance, but no excess growth hormone) may be caused by long-term use of the hair-loss drug minoxidil. [PMID 12789195]