I tried this product for about three weeks and am leaving it off for a few days. It seemed to relieve some of the numbness in my legs but the pain level increased quite a bit. I believe it to be an effective antiinflammatory but I react dfferently than many people when it comes to pain-relieving products, often with more pain. I was taking two gels a day. Will try cutting back to one after a few days off. Have read of an RA trial where the participants reacted with more pain initially but later got relief from evening primrose oil. Hopefully this will be a personal finding also.