Colledge was selected by the Packers in the second round (47th overall) of the 2006 NFL Draft, the highest-ever selection from the state of Alaska. During his fifth and final season in Green Bay in 2010, the Packers won Super Bowl XLV. He became an unrestricted free agent and on July 29, 2011, Colledge announced on his Twitter page that he and the Arizona Cardinals agreed to a 5-year contract.[1]

On March 8, 2014 Arizona told Colledge he would be released into free agency on Tuesday, March 11. By waiting until Tuesday, the Cardinals can spread the cap charge of releasing Colledge over two years. [4]

On June 30, 2014 the Miami Dolphins acquired Daryn Colledge through free agency, signing him to a one-year contract worth $2,000,000. [5][6]