Nineteen people have died and more than 50 others are injured following a suspected terror attack at the Manchester Arena.

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Greater Manchester Police said the explosion at the concert venue, which happened just before 10.35pm on Monday, is being treated as a suspected terror incident.

Witnesses reported hearing a “huge bang” at the 21,000-capacity venue at the end of a sell-out gig by American singer Ariana Grande.

Videos from inside the venue show fans running and screaming, while footage from outside captures emergency vehicles rushing to the scene.

:: LIVE – Several dead in Manchester explosion

Armed police filled the streets outside the arena, and bomb disposal units, firefighters and paramedics also attended the scene.

Fifty-nine people have been taken for treatment at six hospitals around the city.

Sky News Home Affairs correspondent Mark White said hospitals in the area were treating “a number of people with what are believed to be shrapnel-type injuries”.

Police have warned people to stay away from the venue.

:: Witness – ‘People were running and screaming’

Greater Manchester police’s Chief Constable Ian Hopkins said the force was working closely with the counter-terror officers and UK intelligence partners.

He said more details would be provided “when we have a clearer picture”.

Manchester’s Victoria station, which backs onto the arena, has been evacuated and all trains cancelled.

:: Music stars react to ‘attack’

Ariana Grande, who was unharmed, tweeted to say she is “broken”.

“From the bottom of my heart, I am so, so sorry,” she said. “I don’t have words.”

Her manager Scooter Braun said they mourned “the lives of children and loved ones taken by this cowardly act”.

Manchester Arena said the incident had happened outside the venue “in a public space”. Others said it happened close to the ticket offices in a foyer area.

Bomb disposal experts carried out a controlled explosion at nearby Cathedral Gardens shortly after 1.30am, but have since confirmed the item they found was abandoned clothing and not suspicious.

Concert-goers affected by the suspected terror attack have been offered shelter by residents, taxi drivers are said to be offering free rides and there are reports that a hotel near the venue has taken in dozens of children.

Manchester Mayor Andy Burnham tweeted: “My heart goes out to families who have lost loved ones, my admiration to our brave emergency services. A terrible night for our great city.”

Theresa May said her thoughts were with the victims and families of those affected and has condemned “what is being treated by the police as an appalling terrorist attack”.

Conservative and Labour election campaigning has been suspended.

Home Secretary Amber Rudd also condemned the “barbaric attack, deliberately targeting some of the most vulnerable in our society”.

She said: “The full details of exactly what happened are still emerging, but I am proud of the police and first responders who reacted to this tragic incident so swiftly.”

An emergency COBRA meeting is expected to take place in Downing Street at 9am.