Personally, I love the eyes from mangas like Nana, Perfect Girl Evolution, and Kagen no Tsuki. Those are really good examples of a more realistic eye. It looks really good, and reeeeeally gorgeous.

The ginormous eyes of some animes and mangas don't always appeal to me. Himekei Doll has eyes that I truly don't like waaay too big) but the story is good. Also, when you look at the eyes from Fruits Basket, you can see that the eyes are really really really wide. They sometimes even go to the ends of the faces.