glycoprotein

glycoprotein

any of a class of conjugated proteins consisting of a compound of protein with a carbohydrate group.

α1-acid glycoprotein an acute phase protein found in blood plasma, an indicator of tissue necrosis and inflammation. Called also orosomucoid.

P-glycoprotein a cell-surface protein occurring normally in the colon, small intestine, adrenal glands, kidney, and liver, and also expressed by tumor cells. It is a modulator of multidrug resistance, mediating the transport of antineoplastic agents out of tumor cells.

variable surface glycoprotein any of several glycoproteins that form the antigenic protein coating of Trypanosoma brucei. The organisms contain numerous genes encoding hundreds of such glycoproteins and, by expressing individual ones successively, evade the immune system of the host.

gly·co·pro·tein

(glī'kō-prō'tēn),

1. One of a group of proteins containing covalently linked carbohydrates, among which the most important are the mucins, mucoid, and amyloid. See also: mucoprotein.

2. Proteins containing small amounts of carbohydrate, in contrast to mucoids or mucoproteins, usually measured as hexosamine; such conjugated proteins are found in many places, notably γ-globulins, α1-globulins, α2-globulins, and transferrin, and are contained in mucus and mucins. See also: mucoprotein.

glycoprotein

/gly·co·pro·tein/ (-pro´tēn) a conjugated protein covalently linked to one or more carbohydrate groups; technically those with less than 4 per cent carbohydrate but often expanded to include the mucoproteins and proteoglycans.

glycoprotein

(glī′kō-prō′tēn′, -tē-ĭn)

n.

Any of a group of conjugated proteins having a carbohydrate as the nonprotein component.

glycoprotein

[glī′kōprō′tēn]

Etymology: Gk, glykys, sweet, proteios, first rank

any of the large group of conjugated proteins in which the nonprotein substance is a carbohydrate. These include the mucins, the mucoids, and the chondroproteins.

gly·co·pro·tein

(glī'kō-prō'tēn)

1. One of a group of protein-carbohydrate compounds (conjugated proteins), among which the most important are the mucins, mucoid, and amyloid.

2. Sometimes restricted to proteins containing small amounts of carbohydrate, in contrast to mucoids or mucoproteins. See also: mucoprotein

glycoprotein

Any member of a class of proteins linked to carbohydrate units. They are called conjugated proteins and are of comparatively small molecular weight. Some, such as follicle stimulating hormone, luteinizing hormone and chorionic gonadotropin, lose their function if the sugar part is removed; others can continue to function even if deglycosylated. Some glycoproteins are cell adhesion molecules.

glycoprotein

glycoprotein

One of a group of conjugated proteins formed by a protein and a carbohydrate, the most important being the mucins (as found in the lens capsule, vitreous humour) and mucoids (as found in bones, cartilage, tendons).

gly·co·pro·tein

(glī'kō-prō'tēn)

One of a group of proteins containing covalently linked carbohydrates, among which the most important are the mucins, mucoid, and amyloid.

glycoprotein

any of a class of conjugated proteins consisting of a compound of protein with a carbohydrate group.

glycoprotein deficiency

an inherited disorder in dogs in which there is defective phagocytic function. Affected dogs have a marked, persistent neutrophilia and are susceptible to infections.

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