07/17/2013

Abnormal Gluten-Gliadin Antibodies in Autism

Gluten free diet is becoming increasingly popular across the Western society and even more so among those suffering from autism.

While many patients with autism benefit from gluten free diet that concept continues to be challenged by many scientists especially in the context of “biological plausibility” since there has been not much immunological evidence to suggest that subjects react differently to gluten.

Of note, gluten is actually a complex of proteins and gliadin is of the predominant components.

There is an abnormal immunological reaction to gluten among at least a subset of subjects with autism. This is underlying mechanisms appear to be distinct since the anti-transglutaminase antibody response HLA genotypes were not different.

Dr. Minocha's comments

Above results give further credence to the claim that many patients with autism derive benefit from gluten-free diet. As in case of many patients with irritable bowel syndrome related non-celiac gluten-sensitivity, it appears that science may perhaps be lagging behind public driving the gluten-related.

Comments

Tee Shirts Fantastica

Disclaimer Autism

Postings are for general information and not intended for advice or use for self-diagnosis or treatment. I am a gastroenterologist and nutritionist, not your physician or autism specialist. Always read everything on internet with a grain of salt and consult your physician.