Talia Joy Castellano, who was diagnosed with an aggressive cancer six years ago, refused to let her illness keep her down, becoming a YouTube sensation, an honorary CoverGirl, and a guest on “The Ellen Show” by age 13. Now fans around the world are mourning her loss. NBC’s Gabe Gutierrez reports.

BrandIndex, a company that ranks brand perception among consumers, has released their list of the American brands with the best reputations. Donny Deutsch, chairman of Deutsch Inc., discusses the rankings.

For the first time since they were rescued from a home in Cleveland, the three kidnapping victims who were kept captive for a decade are speaking out in a YouTube video. NBC’s Jeff Rossen reports and Clint Van Zandt discusses the video.

Jasmine Villegas, 19, has racked up 85 million views on her YouTube videos, has Grammy-winning producers eager to work with her, and, by opening up about a painful abusive relationship through song, is helping fans around the world. NBC’s Diana Alvear reports.

EDITORS' NOTE: Reuters and other foreign media are subject to Iranian restrictions on their ability to report, film or take pictures in Tehran. A frame grab from YouTube shows a woman identified as Neda Agha-Soltan lying on the ground after getting shot in the chest in Tehran June 20, 2009. Irania

People walk by a YouTube sign at the new Google office in Toronto, in this November 13, 2012 file photo. A U.S. judge on May 15, 2013 denied class-action status to copyright owners suing Google Inc over the use of material posted on YouTube without their permission. REUTERS/Mark Blinch/Files (