This year, the Upper East Side's 10065 zip code, where the median asking price of a home is $6.53 million, ranked as the most expensive zip code in the country. It's the only zip code in the country with a median asking price above $6 million.

The median price change for the neighborhood was a staggering 384.9 percent; particularly impressive since 10065 didn't even make the top 15 last year.