Addition to the standard therapy of non-invasive mechanical ventilation. Continuously for the first 24 hours, then trials to discontinuation every 24 hours. Interface adjusted for the associated injuries.

Device: Non-invasive ventilation

Applied continuously for the first 24 hours, then every 24 hours, trial of discontinuation. Interface specific for the associated injuries.

No Intervention: 2

Standard therapy for severe post-traumatic hypoxia: pain control with epidural anesthesia and oxygen.

Eligibility

Ages Eligible for Study:

18 Years and older

Genders Eligible for Study:

Both

Accepts Healthy Volunteers:

No

Criteria

Inclusion Criteria:

Age > 18 years.

Informed consent obtained.

pO2/FiO2 <200 for more than 8 consecutive hours in the first 48 hours after thoracic trauma.

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For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00557752