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The discovery of the bodies of two young gay men who were both meth addicts as well as victims of a new strain of AIDS that can kill its victims in less than a year leads to an investigation. Tutuola learns that his son, Ken, is gay, and has difficulty accepting it, even though he and Benson end up going to Ken for help with infiltrating an anti-meth group.

The group's leader, Gabriel, soon becomes their top suspect when the squad realises that the two men died because they passed the disease on. The two man had been having indiscriminate sex while high on meth, and spreading the killer disease to others who would do the same. Gabriel believed that since the two wouldn't stop themselves that killing them was the only way to control the spread.

In the end , to the shock of Tutuola Robin's father gives a testimony asking him to be lenient on Gabriel, as while he does not approve of the man killing his son he knows that he did it with the intention of of saving lives from the killer strain. Gabriel gets the minimum for murder which is 15 years. Tutuola is seen at the end calling a number on a phone, presumably his son's.

Goof: At the first murder scene, the CSI officers are shown photographing the storefront with flash photography. Since it is dark outside, the resulting photographs will consist of a reflection of the light from the flash rather than the crime scene inside the store display.