Anencephaly

Anencephaly

Anencephaly is a neural tube defect in embryological development that occurs when the cephalic (head) end of the neural tube fails to close, usually between the 23rd and 26th days of pregnancy, resulting in the absence of a major portion of the brain, skull, and scalp. Infants with this disorder are born without a forebrain, the largest part of the brain consisting mainly of the cerebrum, which is responsible for thinking and coordination. The remaining brain tissue is often exposed and is not covered by bone or skin. Anencephaly is incompatible with life.