Effectiveness of the National PMTCT Program in Rwanda

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Presentation on theme: "Effectiveness of the National PMTCT Program in Rwanda"— Presentation transcript:

1 Effectiveness of the National PMTCT Program in RwandaByDr Alexandre LYAMBABAJE, School of Public Health/ National University of RwandaDr Placidie MUGWANEZA, Institute of HIV Diseases Prevention and Control (IHDPC/RBC), Rwanda

5 Limitations of the 1st PMTCT effectiveness studyRecall bias: 9 to 24 months is a long period after birth. Some mothers could not recall exactly events and treatments during pregnancy and delivery periodsEnd point measurement: Wide interval ( months) making it difficult to interpret the HIV free- survival rate, as we could not rule out exposure to breastfeedingAdherence to PMTCT regimens: Registries could not provide exhaustive information about the adherence of the mothers to PMTCT regimens.

10 Challenges and Potential BiasOutreach Immunization strategyHow to integrate screening for the study?How to administer the questionnaire?Who will manage the transfer of potential eligible mothers and infants to Health facilities for further screening?Reaching the hardest to reach populations: do not participate in immunization campaigns (Beliefs, Ignorance, hard to reach areas)Long period for data collection (7 months)Health Center Personnel mobility

11 Advantages and Disadvantages compared to MRC Generic ProtocolLow cost for blood samples collection and testingZero risk for non-exposed childrenCapacity building for health facilities and better sustainabilityBetter coverage by including recruitment from outreach immunization strategyDisadvantagesDifficult screening phase to identify exposed childrenLong period for data collection (7 months)Mobility of trained personnel and need to retrain new people for data collection

12 Thank You For Your Attention - MURAKOZEAcknowledgementsRwanda Biomedical Center/Institute of HIV, Diseases Prevention and Control (RBC/IHDPC)Rwanda School of Public HealthLABORATOIRE NATIONAL DE REFERENCENATIONAL REFERENCE LABORATORYThank You For Your Attention - MURAKOZE