Many studies are so thin on details, they’re unverifiable, unusable, or both. Many are too small, badly designed, or otherwise unreliable – and then the results are misinterpreted, the validity exaggerated. Many aren’t

It’s not a new story, although “the reproducibility crisis” may seem to be. For life sciences, I think it started in the late 1950s. Large-scale problems in clinical research burst into the open in a very public

Psychology has a meta-analysis problem. And that’s contributing to its reproducibility problem. Meta-analyses are wallpapering over many research weaknesses, instead of being used to systematically pinpoint them. It’s a bit of a case of a prophet

The hunt for p-values less than 0.05 has left many of science’s roadways riddled with potholes. More than 50% of them in the biomedical literature are wrong, according to one reckoning, maybe 30% or more wherever