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Laurel seeks Luke's help after discovering that a senate bill is not what it appears; Red and Ella square off in an effort to control the bug agenda. Later, Laurel questions whether she's cut out for life in Washington, D.C.

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Laurel becomes infected by the bugs, so Gustav and Rochelle try to figure a way to save her; and funding is temporarily cut for the Centers for Disease Control, forcing Luke to reach a compromise to get the money reinstated, but Red is determined to undermine his efforts.

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Laurel seeks her brother's help in getting the Center for Disease Control and Prevention involved in the case, but first he wants her to consult with a noted entomologist about the bug invasion. Later, Laurel's relationship with Anthony takes a turn.

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Laurel and Rochelle lean on Laurel's friend Abby to take an MRI so they can get to the bottom of what's behind the cause of the strange behavior taking over Washington, D.C. Later, Luke tries to reopen the government via a clandestine deal with the Republicans.

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A fatal incident on live television leads Laurel, Gustav and Rochelle to intensify their investigation into the bug mystery, while Luke scrambles to cover up his affair with his chief of staff before the minority whip spills it to the public.

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As more bugs infect Washington, D.C., citizens, Laurel's investigation into Dr. Daudier's death continues. Meanwhile, the deceased doctor's daughter and eccentric genius Gustav Triplette encounter the bugs separately and begin to ponder just what is going on.

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Series Premiere of a comedy thriller about a woman who returns to Washington, D.C., to help her senator-brother and discovers aliens have invaded the Hill and made a scary impact on congressmen and staffers.