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Photos: 13 NFL questions for 2013

1. ARE THE PATRIOTS IN TROUBLE?: This has nothing to do with the law, either. New England won't have Wes Welker, Brandon Lloyd, Aaron Hernandez, and there's a good chance Rob Gronkowski when Week 1 arrives. That's an awful lot of production Tom Brady has lost.

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Photos: 13 NFL questions for 2013

1. ARE THE PATRIOTS IN TROUBLE?: This has nothing to do with the law, either. New England won't have Wes Welker, Brandon Lloyd, Aaron Hernandez, and there's a good chance Rob Gronkowski when Week 1 arrives. That's an awful lot of production Tom Brady has lost. Greg M. Cooper, USA TODAY Sports

2. WHICH TEAM IS TOPS IN THE LOADED NFC WEST?: There are two championship contenders (49ers and Seahawks) and no obvious doormat among the teams. Both the Rams and Cardinals will be greatly improved. Steven Bisig, USA TODAY Sports

3. CAN LAST YEAR'S ROOKIE QB CLASS AVOID A SOPHOMORE SLUMP?: Andrew Luck (pictured), rookie of the year Robert Griffin III, Russell Wilson, and Ryan Tannehill will have to show they can improve on their stellar first seasons. Andrew Weber, USA TODAY Sports

5. CAN ANYTHING SAVE REX RYAN?: The Jets have a new GM, and a quarterback battle happening between Mark Sanchez and Geno Smith. Everything has to go right for Rex to keep his job. Brad Penner, USA TODAY Sports

7. WILL THE NFL'S LATEST MAJOR SAFETY MEASURE MEAN BIG FINES FOR ITS STARS?: Running backs, such as Arian Foster, no longer being allowed to lower the heads is an issue to watch this season. Brett Davis, USA TODAY Sports

9. WHICH NEW COACH HAS THE BEST CHANCE FOR AN INSTANT TURNAROUND?: Bruce Arians filled in admirably last year as the Colts' interim head coach while Chuck Pagano was sidelined with leukemia. Arians now has his hands full trying to lead the Cardinals in the NFL's toughest division. Mark J. Rebilas, USA TODAY Sports