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The Cochrane Database of Systematic Reviews is considered the gold standard for
evidence-based medicine. Essential Evidence Plus includes the latest and most
up-to-date summaries of systematic reviews from the Cochrane Library, which are
the most rigorous and reliable evaluations of medical therapies available. You’ll
find summarized evaluations of the world’s best literature on the effectiveness of
therapy for 3,300+ clinical problems.

Drug-eluting stents versus bare-metal stents for acute coronary syndromeCochrane Systematic Reviews, 21-Aug-2017Approximately 3.7 million people died from acute coronary syndrome worldwide in 2012. Acute coronary syndrome, also known as myocardial infarction or unstable angina pectoris, is caused by a sudden blockage of the blood supplied to the heart muscle. Percu

Drugs for discoid lupus erythematosusCochrane Systematic Reviews, 5-May-2017Discoid lupus erythematosus (DLE) is a chronic form of cutaneous lupus, which can cause scarring. Many drugs have been used to treat this disease and some (such as thalidomide, cyclophosphamide and azathioprine) are potentially toxic. This is an update of

Drugs for preventing lung cancer in healthy peopleCochrane Systematic Reviews, 6-Sep-2012This is an updated version of the original review published in Issue 2, 2003. Some studies have suggested a protective effect of antioxidant nutrients on lung cancer. Observational epidemiological studies suggest an association between higher dietary leve

Drugs for preventing migraine headaches in childrenCochrane Systematic Reviews, 17-Feb-2017It has been estimated that about 10 per cent of children between 6 and 20 years of age suffer from migraine, and that children with migraine lose one and a half weeks more schooling per year than their peers. Prophylactic drugs can be prescribed when chil

Drugs for the acute treatment of migraine in children and adolescentsCochrane Systematic Reviews, 18-Apr-2016Numerous medications are available for the acute treatment of migraine in adults, and some have now been approved for use in children and adolescents in the ambulatory setting. A systematic review of acute treatment of migraine medication trials in childr

Drugs for treating giardiasisCochrane Systematic Reviews, 12-Nov-2012Giardiasis infection may be asymptomatic, or can cause diarrhoea (sometimes severe), weight loss, malabsorption, and, in children, failure to thrive. It is usually treated with metronidazole given three times daily for five to 10 days.

Drugs for treating giardiasisCochrane Systematic Reviews, 13-Nov-2008There can be a high rate of recurrence of disease after initial drug treatment for giardiasis. These drugs also have a range of adverse effects.

Drugs for treating paracoccidioidomycosisCochrane Systematic Reviews, 30-Jun-2011Paracoccidioidomycosis is a fungal infection that occurs only in some particular places in Latin America. Treatment is long, the drugs have side effects, and patients can relapse. However, the disease is potentially fatal.

Drugs for treating Schistosoma mansoni infectionCochrane Systematic Reviews, 29-Jan-2013Schistosoma mansoni is a parasitic infection common in the tropics and sub-tropics. Chronic and advanced disease includes abdominal pain, diarrhoea, blood in the stool, liver cirrhosis, portal hypertension, and premature death.

Drugs for treating urinary schistosomiasisCochrane Systematic Reviews, 7-Jul-2014Urinary schistosomiasis is caused by an intravascular infection with parasitic Schistosoma haematobium worms. The adult worms typically migrate to the venous plexus of the human bladder and excrete eggs which the infected person passes in their urine. Chr

Drugs for treatment of urinary retention after surgery in adultsCochrane Systematic Reviews, 6-Sep-2010Post-operative urinary retention, the inability to void following surgery despite a full bladder, is usually transitory but can be prolonged in some cases. It can lead to several complications including urinary tract infection, long term bladder dysfuncti

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