1. Depart,retire,retreat,withdraw imply leaving a place. Depart is a somewhat literary word for going away from a place: to depart on a journey.Retire emphasizes absenting oneself or drawing back from a place: to retire from a position in battle.Retreat implies a necessary withdrawal, especially as a result of adverse fortune in war: to retreat to secondary lines of defense.Withdraw suggests leaving some specific place or situation, usually for some definite and often unpleasant reason: to withdraw from a hopeless task.4. quit.

As a euphemism for "to die" (to depart this life; cf. Old French departir de cest siecle) it is attested from c.1500, as is the departed for "the dead," singly or collectively. Transitive lingers in some English usages; the wedding service was till death us depart until 1662. Related: Departed; departing.