Episodes of asthma and rhinoconjunctivitis Allergy tests showed that skin prick tests were only mildly positive for oilseed rape flour, and the peak respiratory flow only slightly decreased during exposure

Patient 1: history of IgE-dependent rhinitis since childhood; urticaria angioedema episodes related with shellfish. Patient 2: history of IgE-dependent asthma and rhinitis and urticaria to latex. Patient 3: history of IgE-dependent rhinitis

Mustard sauce

Oral

Acute ingestions

Not specified

Patient 1: episodes of pruritus, swelling of tongue, dysphagia, dysphonia, facial edema, and progressive upper respiratory difficulty. On one occasion, he experienced hypotension, and on another urticaria and palpebral edema. Patient 2: episodes of pruritus, swelling of lips and tongue, and edema. Patient 3: dysphonia, dysphagia, progressive upper respiratory difficulty, and generalized urticaria. Upon allergy testing, patients were found to be allergic to mustard

Patient 1 had suffered from dermatitis ever since she was 15, which worsened when handling cattle food. Patient 2: itching and erythematous papules for the past 1.5 years, for which she was treated

Patient 1: mustard; Patient 2: mustard khal

Topical

Chronic (exact duration not mentioned)

NA

Patient 1: itching and erythmatous papular lesions on forearms, arms, neck, forehead, ear lobules, and sides of face for the past 8 months. Patient 2: itching and erythmatous papules on forearms, forehead, cheeks, ear lobules, neck, and dorsum of feet for the past 1.5 years. Upon allergy testing, patient 1 found to be allergic to mustard, jowar flour, and wheat flour. Patient 2 found to be allergic to mustard khal and maize

Not mentioned (it is mentioned that treatment was given, but no further details are provided)

Improved with treatment, but authors do not mention what happens when not exposed

Possibly (patient 1), unlikely (patient 2)

Patient 1 had been using mustard oil for years and only lately did she start experiencing adverse event. Patient 2 did not report any exposure to mustard

Patient 1: for past 7 years: pruritus, erythema, vesicles, fissures, and peeling in both hands, as well as facial angioedema, within 6–8 h after handling broccoli. Patient 2: asthma; in past 4 years, papules and vesicles in both hands and eyelids 24–36 hours after exposure to cauliflower or broccoli

Authors labeled case as toxic irritative dermatitis and NOT an allergic reaction and warn against use of home-made medications

1Route of exposure. 2Duration of exposure. 3NA, not applicable, in cases where dose cannot be quantified. 4Degree of resolution in cases here adverse events were reported; NA, not applicable. 5The degree of association between the intervention and the adverse event, as rated by reviewers; NA, not applicable.