The case intrusion sensor detection might be a 'sticky' information - it's reported as "open" until you reset that information. Does it report intrusion immediately after reboot?
As for the voltage readings, this mainboard needs specific adjustment. Please send me a HWiNFO32/64 Report File, Debug File including sensor data and a photo of the BIOS system health screen. Then I can fix it.

I have verified the data I receive from chip and according to documentation there's really "Chassis intrusion" being reported.
I'll fix the voltage and temperature values (in next build) to be reported the same way as BIOS. AVCC3 is the +3.3V rail from which the sensor is powered, however +5V and +12V rails don't seem to be monitored on this mainboard (the BIOS doesn't report them too).