Doctor insights on:
Bupropion Overdose In Children

1

Talk to Doctor:
Wellbutrin, (bupropion) like any other medication, can be overdosed. You need to counsel with the prescribing physician. He/she will give the information you need to understand your dosage.
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The highest dose that should be taken in an adult is 450mg of wellbutrin XL which is a dose that would be worked up to over time. Overdose symptoms can include: rapid heart rate, feeling jittery, confusion, visual changes, nausea, vomiting, seizures, heart failure, loss of consciousness and death.
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2

Not sure of question:
Bupropion is used to treat depression & nicotine dependence. Works by increasing norepinephrine & dopamine. Because it is activating it is useful for patients with lethargic depression. Bupropion is not associated with weight gain or sexual problems. Overdoses are associated with an increased risk of seizures, changes in heart rate, fever, and breathing. Overdoses may cause coma & death.
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3

Blood test:
Wellbutrin (bupropion) will show up on special blood tests which look specifically for wellbutrin (bupropion). This testing will show the amount of wellbutrin (bupropion) in your system, so doctors will be able to tell if it’s consistent with normal prescription use or is at a harmful level.
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4

Buproprion OD:
The highest dose that should be taken in an adult is 450mg of wellbutrin XL which is a dose that would be worked up to over time. Overdose symptoms can include: rapid heart rate, feeling jittery, confusion, visual changes, nausea, vomiting, seizures, heart failure, loss of consciousness and death.
...Read more

5

Wellbutrin OD:
The highest dose that should be taken in an adult is 450mg of wellbutrin XL which is a dose that would be worked up to over time. Overdose symptoms can include: rapid heart rate, feeling jittery, confusion, visual changes, nausea, vomiting, seizures, heart failure, loss of consciousness and death.
...Read more

10

Wellbutrin (bupropion):
Wellbutrin (bupropion) selectively inhibits the reuptake of Dopamine and norepinephrine by neurons, so that more of these neurotransmitters is available at synapses. This may not explain the entire mechanism of action as an antidepressant or smoking-cessation aid, but it's the best we know so far.
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15

Well......:
Officially you should not, however the mechanism with which wellbutrin (bupropion) sr provides sustained release would be maintained if it is halved without crushing. This is not the case with wellbutrin (bupropion) xl, it can not be divided.
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16

Stopping bupropion:
There are no withdrawal symptoms in stopping bupropion, however whatever condition you have been using the bupropion to treat may recur or intensify. If you have been using this to aid in smoking cessation, your cravings for tobacco may increase and the reward you get from smoking may increase.
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17

Bupropion:
Bupropion is an antidepressant that works on norepinephrine and dopamine. It is in a class of its own. Is the least likely of all of the antidepressants to cause weight gain or induce mania. It also has the lowest risk of sexual side effects. It is additionally approved for the treatment of seasonalmood disorder. If you don't recall if you took a dose you should skip it for that day because as much as doubling the dose can induce a seizure.
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23

Non SSRI antidepress:
Wellbutrin (bupropion) (buproprion hydrochloride) is an antidepressant/anxiolytic that works by inhibiting neuronal uptake of norepinephrine and Dopamine (aminoketone). It is also used for impulsivity as seen in adhd and smoking.

26

Don't understand?:
"for thoughts" doesn't mean anything to me, and doesn't appear on any prescribing information I have found for bupropion. So, I don't really understand your question. The only thing that comes close is a statement that antidepressants can increase suicidal thoughts, especially in younger adults and adolescents. Don't know if that is what you mean.
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27

Consult doctor:
It would not be a good idea to change your medications on your own. You should consult the doctor who prescribed the medications.Exercise can alleviate mild depression and you should try to exercise regularly.For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex.
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28

Fairly mild:
The side effects of bupropion are fairly mild. Most common are a bit of dry mouth, blurry vision or constipation. You may get a little anxious early on. These mostly go away within 2-3 weeks. In high doses, it can cause seizures, though this is fairly rare (i haven't seen a case in 20+ years of prescribing it).
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Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, & elevate blood pressure.
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