Application Information: MAP1 antibody

Western blotting (1-4 µg/ml). However, the optimal concentrations should be determined individually. Jurkat cell lysate and mouse small intestine tissue lysate can be used as positive controls. The antibody recognizes 39 kDa MAP-1 from samples of human, mouse and rat origins. Reactivity to other species has not been determined. In human samples, an additional ~78 kDa dimer can be detected in Jurkat cell lysate. In mouse sample, an additional ~33 kDa cleavage fragment can also be detected in mouse small intestine tissue lysate.

Form Supplied

Liquid

Concentration

0.5
mg/ml
(Please refer to the vial label for the specific concentration)

Purification

Affinity purified

Specifications: MAP1 antibody

Full Name

modulator of apoptosis 1

Background

Human MAP-1 (Modulator of Apoptosis Protein) is a novel Bax-associating protein. MAP-1 mediates caspase-dependent apoptosis in mammalian cells when overexpressed. MAP-1 homodimerizes and associates with the proapoptotic Bax and the prosurvival Bcl-2 and Bcl-XL of the Bcl-2 family.

Synonyms

MAP1A, FLJ77111, MTAP1A, MAP1L, MAP1

Specificity

This antibody is specific for MAP1.

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Species Reactivity

Human, Mouse

Conjugation

Unconjugated

Storage Conditions: MAP1 antibody

Storage Buffer

PBS (pH 7.2) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal

Storage Instruction

The antibody solution should be gently mixed before use. Stored at -20 °C for future use.

Notes

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

MAP1 antibody validated data

GTX59784 WB Image

Western blot analysis of MAP-1 expression in mouse small intestine tissue lysate