Current health care: For many acute and chronic disorders, the current health care outcomes are considered as being inadequate: global figures cry for preventive measures and personalised treatments. In fact, severe chronic pathologies such as cardiovascular disorders, diabetes and cancer are treated after onset of the disease, frequently at near-end stages. Pessimistic prognosis considers pandemic scenario for type 2 diabetes mellitus, neurodegenerative disorders and some types of cancer over the next 10–20 years followed by the economic disaster of health care systems in a global scale.

Advanced health care promotes the paradigm change from delayed interventional to predictive medicine tailored to the person, from reactive to preventive medicine and from disease to wellness. The innovative Predictive, Preventive and Personalised Medicine (PPPM) is emerging as the focal point of efforts in health care. PPPM is the new integrative concept in health care sector that enables to predict individual predisposition before onset of the disease, to provide targeted preventive measures and create personalised treatment algorithms tailored to the person.

In our work we also follow in this area the advice from the Public Health Genomic ( PHGEN) EU network were we participated in this concerted efforts. PHGEN established guidelines for the translation of genetic and molecular methods into use for public health. PHGEN >>>