im on a new anxiolytic called buspar (buspirone), and i was wondering if it’ll have any interactive effects with marijuana, MDMA, DMT, or LSD??? There are no studies available about clinical interactions between buspirone and psychedelic drugs....

I was wondering if you knew of any long term effects (postive or negative) from DMT use (heavy or not). As many other “classical psychedelics” organic toxicity of DMT is practically nonexistent. There are no reported cases of...

with the above post in mind do you know of any complications with taking DMT and methadone maintenance? Or what about complications with taking MAOIs like Caapi vine or syrian rue in ayahuasca when on methadone maintenance? There are no known...

what if i mixed St Johns Wort with smoked DMT? Hypericum perforatum (St John´s Wort) acts as an antidepressant. There are many drugs that can interact with this plant, and some of these interactions are relevant. Hypericum elevates serotonin...

A friend is interested in trying DMT after I recently introduced her boyfriend to it. There is a history of schizophrenia in her family while she herself has been diagnosed as being on the autistic spectrum. She is also currently diagnosed with depression and...