Typhoid is a serious systemic illness commonly presenting with fever and abdominal symptoms. However, it very rarely can manifest without any gastrointestinal symptoms and with acute indolent neurological features only which can pose a diagnostic challenge. We had a such a case which took a fatal course later on with sepsis, disseminated intravascular coagulation (DIC) and multi-organ failure. We did a literature survey on the unusual and extra-intestinal features of the disease. We found when associated with serious neurological findings, the disease has a worse prognosis. Vaccines along with public awareness should be promoted in endemic zones as the disease can often otherwise take a complicated course with high morbidity and mortality.