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Two of Europe's big guns come face to face at the Santiago Bernabéu in the round of 16 as Real Madrid CF's bid to win three UEFA Champions League titles in a row comes under threat from Paris Saint-Germain.

• Madrid finished second to Tottenham Hotspur FC in Group H – the second year running they have been runners-up in their section – while Paris won their first five Group B games to top the standings ahead of FC Bayern München.

• However, while the Spanish side have got to the semi-finals or better in each of the last seven seasons, Paris will need no reminding of their remarkable exit at this stage at the hands of FC Barcelona 12 months ago – their most recent tie against Spanish opponents.

Previous meetings• The teams last met in the 2015/16 group stage, when a 0-0 draw in Paris preceded a 1-0 Real Madrid win in Spain, Nacho scoring the only goal in the 35th minute having come on only two minutes earlier. That helped the Merengues to finish first in the section, three points ahead of their French rivals.

• Those 2015 games against Paris were Madrid's last matches against French opposition. They are unbeaten in their last nine such encounters (W6 D3), going back to a 1-0 loss at Olympique Lyonnais in the 2009/10 round of 16 first leg (1-2 aggregate). In those wins they scored 15 goals without reply.

• That 1994 defeat by Paris is the Merengues' only reverse in their 14 matches at home to Ligue 1 visitors (W10 D3). They have won their last four home matches.

• While Madrid have lost both their two-legged knockout ties with Paris, against French clubs overall their knockout record is W3 L4. Their most recent contests were a 4-1 aggregate victory against Lyon in the 2010/11 round of 16 (1-1 away, 3-0 home).

• Champions of Europe for a 12th time in 2016/17 – courtesy of their 4-1 final win against Juventus – Madrid aim to become the first team since Bayern München in 1976 to claim three successive European Champion Clubs' Cups. AFC Ajax (1971–73) and Madrid themselves (1956–60) are the only other sides to have won three or more in a row.

Paris• This is Paris' sixth successive round of 16 tie – and also their sixth overall. They won the first four, but exited in dramatic circumstances at this stage 12 months ago.

• The Parisians have won seven of their last 12 away fixtures in the competition, winning 5-0 at Celtic and 4-0 at Anderlecht this season; they have lost four games in that run. Matchday one was their first clean sheet in seven away matches; they subsequently managed another at Anderlecht.

• The French club's record in two-legged ties against Spanish sides is W5 L3. Those three defeats have come in the three most recent contests, all against Barcelona – in last season's round of 16 and the quarter-finals of 2015 and 2013.

• Paris have never lost the first leg of a round of 16 tie (W4 D1).

Coach and player links• Zinédine Zidane faced Paris four times as a player for FC Girondins de Bordeaux and Juventus (W2 D1 L1).

• Draxler's VfL Wolfsburg beat Real Madrid 2-0 in the first leg of the 2015/16 quarter finals; he was also in the side that succumbed to a Ronaldo hat-trick in a 3-0 second-leg turnaround in Spain.

• Raphaël Varane's fifth game in the RC Lens first team was a Coupe de France tie at Paris in January 2011; his side lost 5-1. Varane did help Lens to a 0-0 Ligue 1 draw at the Parc des Princes the following month.

• Karim Benzema faced Paris seven times during his time in France with Lyon (W4 D2 L1). He was part of the Lyon team that beat Paris 1-0 in the Coupe de France final in May 2008.

• Marcelo scored Madrid's goal in a 3-1 defeat by Paris in an Ohio friendly in 2016.

• Alphonse Areola helped Villarreal CF to a 1-0 Liga win against Madrid in December 2015 during a season-long loan spell at the Yellow Submarine.

• A Germany team including Trapp, Kroos and Draxler drew 2-2 against France, who fielded Mbappé, Rabiot, Varane and substitute Kurzawa, in a friendly on 14 November 2017.

Match facts

Real Madrid• UEFA Champions League squad changesIn: NoneOut: None

• Dani Carvajal completes a two-match ban in the first leg against Paris.

• Ronaldo scored nine goals in the group stage – three more than any other player. He also had 21 shots on target and 18 shots off target, also competition highs.

• Madrid have won just four of their eight Liga fixtures since matchday six, losing two, although they were 5-2 winners at home to Real Sociedad de Fútbol on Saturday.

• Ronaldo got a hat-trick against La Real; he has scored seven goals in his last four Liga appearances, but has only 11 strikes in the league this season.

• Zidane's side lifted the FIFA Club World Cup for the second year in a row – and the third time in four years – with a 1-0 defeat of Brazil's Grêmio FBPA on 17 December. Ronaldo scored the winner having also been on target in the 2-1 semi-final win against Al Jazira Club of the UAE.

• Madrid were knocked out of the Copa del Rey in the quarter-finals, losing on away goals to CD Leganés. A 1-0 away win in the first leg preceded a 2-1 home reverse.

• Gareth Bale has five goals in his last seven games in all competitions.

• Karim Benzema is without a league goal since 25 November.

• Madrid have kept only two clean sheets in their last 11 games in all competitions, both in the Copa del Rey. They have conceded at least once in every league game since the 5-0 defeat of Sevilla FC on 9 December.

• Ronaldo, Sergio Ramos, Marcelo, Toni Kroos and Luka Modrić were all included in the UEFA.com Fans' Team of the Year 2017.

• Paris have lost only one of their 15 games in all competitions since matchday six, winning the rest; they went down 2-1 at Olympique Lyonnais on 21 January. That was only the Parisians' third reverse of the season in all competitions; they have played 38, winning all but five.

• Paris were 1-0 victors at Toulouse FC on Saturday, Neymar scoring the only goal. The Brazilian has 11 goals in his last seven appearances in all competition.

• Unai Emery's side beat Stade Rennais FC 3-2 in the French League Cup semi-finals on 30 January to reach another final in the competition. Paris play AS Monaco FC in Bordeaux on 31 March seeking a fifth straight title, and a record eighth League Cup.

• Paris progressed to the French Cup quarter-finals with a 4-1 win away to Ligue 2 side FC Sochaux-Montbéliard on 6 February, Ángel Di María scoring his first hat-trick since registering three in SL Benfica's 4-0 victory at Leixões SC in the Portuguese Liga on 27 February 2010. Paris lost goalkeeper Kevin Trapp to a late red card at Sochaux.

• The Parisians take on Olympique de Marseille in the quarter-finals on 27/28 February.

• Paris have now gone four years undefeated in domestic cup competitions, winning 38 games in a row since 22 Jan 2014, when they lost 2-1 at home to Montpellier in the Coupe de France round of 32.

• Dani Alves was included in the UEFA.com Fans' Team of the Year 2017.