So Durham University used the Valve Source engine to rebuild several university departments. Then they virtually set them on fire. This allowed them to study how people reacted to the fire and simulated the escape routes and methods.

Except for one minor flaw:

However, while the simulation worked for most people, those who played a lot of video games did rather unusual things.

"If a door was on fire, they [gamers] would try and run through it, rather than look for a different exit," said Dr Smith.

This makes sense to me. Hunt for shotgun, shoot open flaming door, run through. Seen it, done it.