e-GRASP is a web-resource developed to enable the query and exploration of the information contained in the GRASP2
database (Eicher et al., 2015) alongside
evolutionary information which we have added for each single nucleotide polymorphism (SNP). This evolutionary information
can be used to prioritize SNPs with a greater likelihood of bona fide and reproducible genetic disease associations
(Dudley et al., 2012).

To make queries faster, we have used relevant information from the GRASP2 database and built an expanded database
containing evolutionary conservation for all SNP positions and disease-mutation diagnosis information for missense
SNPs (Kumar et al., 2012 and
Liu and Kumar, 2013).

Because GRASP2 is a publicly available genome-wide association study results, which has been directly used here,
we recommend that all researchers, students, and clinicians make sure to cite the original contribution
(Eicher et al., 2015) when referring to
the use of E-GRASP. E-GRASP itself may be cited alongside, as appropriate.