Dr. Gaston was the first African American woman to direct a Public Health Service Bureau.

One day I was in the living room with my mother... and that day she fainted in the living room. And I had no idea what was wrong. It was very frightening to me, and back then we didn't have 911 and so I didn't really know what to do... she had cancer of the cervix. We were poor, we were uninsured, she was not getting health care, ...and that's why she fainted. And from that point on, I knew that I wanted to do somthing to change that situation.

Marilyn Hughes Gaston, M.D., faced poverty and prejudice as a young student, but was determined to become a physician. She has dedicated her career to medical care for poor and minority families, and campaigns for health care equality for all Americans. Her 1986 study of sickle-cell disease led to a nationwide screening program to test newborns for immediate treatment, and she was the first African American woman to direct a public health service bureau (the Bureau of Primary Health Care in the United States Department of Health and Human Services).

By the time she was 9 years old, Marilyn Hughes knew she wanted to be a doctor, but because she was poor and black, she was dissuaded from pursuing her dream. She studied zoology at Miami University, and when she graduated in 1960, she enrolled at the University of Cincinnati College of Medicine, encouraged by a physician she worked for. When she began medical school, she was one of only six women, and the only African-American woman in her year.

Dr. Gaston first became interested in the problems of children with sickle cell disease (SCD) while doing her internship at Philadelphia General Hospital in 1964. SCD is an inherited blood disorder that results in chronic anemia and recurring episodes of pain. In a person with SCD, some blood cells take on a sickle-like, crescent shape, causing hemoglobin to clump and block the capillaries, ultimately damaging blood-starved tissues. Over time, it can cause weakness, even death, especially for patients in developing nations, where treatment is not readily available. According to the Sickle Cell Disease Association of America, each year approximately a thousand babies are born with the disease in America.

One evening, during her internship, Dr. Gaston admitted a baby with a badly swollen hand. No trauma was reported, and she could not find the cause of the swelling. Her supervising resident suggested she check the blood work for evidence of sickle cell disease. The child did have SCD, and his hand was swollen from infection. Gaston was appalled that she hadn't even considered checking for this condition, and set out to learn everything she could about it. She secured federal grants to study SCD in children and established protocols for routine screening for the disease. In 1976 she began a long association with the National Institutes for Health as a medical expert, and later, as deputy branch chief of the Sickle Cell Disease Branch.

In 1986 Dr. Gaston published the results of a groundbreaking national study that proved the effectiveness of giving SCD children long-term penicillin treatment to prevent septic infections. Her study showed that babies should be screened for SCD at birth, so that preventive penicillin could be given right away. The study resulted in Congressional legislation to encourage and fund SCD screening programs nationwide. Within one year, forty states had begun screening programs. One of the most important conclusions of her work was the ease with which the complications of Sickle Cell Disease could be avoided with early treatment, a life-saving practice that became a central policy of the U.S. Public Health Service.

In 1990, Dr. Gaston went on to become director of the Bureau of Primary Health Care in the U.S. Health Resources and Services Administration, the first African American woman to direct a public health service bureau, where she focused on improving health care services for poor and underserved families. She controlled a budget of $5 billion serving 12 million patients. When Dr. Gaston retired in 2001, her staff presented her with newly received data from prophylactic penicillin programs recently carried out in Africa, underscoring the worldwide impact of her work.

Her scientific achievements, as well as her ongoing commitment to improving the health of poor and minority Americans, have been recognized in many awards and honors, including every award given by the Public Health Service, and the most prestigious honor awarded by the National Medical Associationthe NMA Scroll of Merit, in 1999. She also received the NMA's Lifetime Achievement Award, several honorary degrees, and is celebrated on "Marilyn Hughes Gaston Day" in Cincinnati and Lincoln Heights, Ohio. The University of Cincinnati College of Medicine has named a scholarship in her honor, giving full medical scholarships to two underprivileged minority students each year. The scholarships help other young people facing discrimination and financial hardship to pursue their own dreams of a career in medicine.