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Mr. Burns states that, although there is an outside chance of seven misfortunes, nine misfortunes befalling his players is virtually impossible. Indeed, this proves accurate as nothing happens to either Darryl Strawberry or Don Mattingly. The latter only fails to play because of Burns' misunderstanding of what sideburns are.

The players in this episode were an extremely talented group. They combined for 77 All Star selections, 34 Gold Gloves, 7 Cy Youngs, and 4 league MVP awards. They also won a combined 12 World Series. Smith and Boggs are presently the only members of the Baseball Hall of Fame from this group, although several players are not yet eligible for election. Following Ken Griffey, Jr's 2010 retirement, none of the episode's baseballers remain active players. As of December 2006, Mike Scioscia manages the Los Angeles Angels of Anaheim, José Canseco plays for the Long Beach Armada in the Independent Golden Baseball League, and Don Mattingly manages the Los Angeles Dodgers. At the time, only Steve Sax and Don Mattingly had played for the New York Yankees. Four of the other ringers would later play for the Yankees (Boggs, Clemens, Canseco, and Strawberry).

Don Mattingly being forced by Burns to cut his sideburns was, coincidentally, recorded a year before Mattingly was forced in real life to cut his long hair.[2]At the time of the episode, Mattingly played for the New York Yankees, a professional baseball team whose owners are heavily strict about hairstyles, especially facial hair.

Jose Canseco was said to be the most difficult of the players featured to work with. His reason for missing the game was originally intended to be different, but Canseco balked and wanted more of a "heroic" reason, hence the fire scene.

Lisa's explanation to Marge, that Homer getting hit by pitch counted as a hit, is incorrect. In baseball, when a batter gets hit by pitch, although he may advance to first base, he does not get credit for a hit.

The chalkboard gag implies that Bart knocked a student unconscious with a ball. In the end Homer got knocked unconscious by a ball. Also the next Treehouse of Horror episode Springfield was taken over by zombies which are defeated with shots to the head.

According to the DVD commentary, Harry Shearer hated doing this show, and he was heavily featured as Burns and Smithers were main characters in it. Other problems were that a lot of the show's crew weren't baseball fans, and that the professional baseball players were difficult to schedule for recording. Most of them recorded their lines during road trips to play the Dodgers or Angels. One particularly rough challenge was syncing up the dialogue in the hypnotism scene where the whole team speaks in unison. All the lines were recorded at different times over several months and had to sound like they all spoke at the same time.

Reasons why the professional baseball players (save Daryl Strawberry) were forced to miss the championship game:

Roger Clemens is made to act like a chicken by the team's hypnotist.

Wade Boggs gets punched out by Barney at Moe's Tavern during a heated argument over who is the greatest Prime Minister of England.

Ken Griffey, Jr. overdoses on nerve tonic and devlopss gigantism.

Steve Sax is arrested because the Springfield Police believe he is responsible for all of New York's unsolved crimes.

The episode's title is a play on the Ernest Lawrence Thayer poem "Casey at the Bat".

During the montage of away games, Homer points to center field, which was made famous by an urban legend that Babe Ruth hit a line drive down center field for a hospitalized boy. This was also spoofed in the film The Sandlot which debuted two years after this episode where a kid attempts to duplicate it but strikes out. Homer did hit a home run, albeit by way of left field.

The tale of Homer's homemade bat a takeoff of the plot of The Natural. As in the film, the homemade bat splinters after the protagonist faces a tough pitcher. However, in the film, the bat boy offers Roy Hobbs a homemade bat he had been working on, and the iconic hit is made with that.