<?xml version="1.0" encoding="UTF-8"?>
<StructureDefinitionxmlns="http://hl7.org/fhir"><idvalue="Substance"/><meta><lastUpdatedvalue="2020-06-06T02:25:40.961+00:00"/></meta><text><statusvalue="generated"/><divxmlns="http://www.w3.org/1999/xhtml"><tableborder="0" cellpadding="0" cellspacing="0" style="border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;"><trstyle="border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;"><thclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"><ahref="formats.html#table" title="The logical name of the element">Name</a></th><thclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"><ahref="formats.html#table" title="Information about the use of the element">Flags</a></th><thclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"><ahref="formats.html#table" title="Minimum and Maximum # of times the the element can appear in the instance">Card.</a></th><thclass="hierarchy" style="width: 100px"><ahref="formats.html#table" title="Reference to the type of the element">Type</a></th><thclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"><ahref="formats.html#table" title="Additional information about the element">Description &amp; Constraints</a><spanstyle="float: right"><ahref="formats.html#table" title="Legend for this format"><imgalt="doco" src="help16.png" style="background-color: inherit"/></a></span></th></tr><trstyle="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;"><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVBORw0KGg
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ABJRU5ErkJggg==" style="background-color: white; background-color: inherit" title="Resource"/><spantitle="Substance : A homogeneous material with a definite composition.">Substance</span><aname="Substance"></a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"><ahref="versions.html#std-process" style="padding-left: 3px; padding-right: 3px; border: 1px grey solid; font-weight: bold; color:
black; background-color: #fff5e6" title="Standards Status = Trial Use">TU</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"/><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"><ahref="domainresource.html">DomainResource</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px">A homogeneous material with a definite composition
<br/>Elements defined in Ancestors:
<ahref="resource.html#Resource" title="The logical id of the resource, as used in the URL for the resource. Once assigned, this
value never changes.">id</a>,
<ahref="resource.html#Resource" title="The metadata about the resource. This is content that is maintained by the infrastructure.
Changes to the content might not always be associated with version changes to the resource.">meta</a>,
<ahref="resource.html#Resource" title="A reference to a set of rules that were followed when the resource was constructed, and
which must be understood when processing the content. Often, this is a reference to an
implementation guide that defines the special rules along with other profiles etc.">implicitRules</a>,
<ahref="resource.html#Resource" title="The base language in which the resource is written.">language</a>,
<ahref="domainresource.html#DomainResource" title="A human-readable narrative that contains a summary of the resource and can be used to
represent the content of the resource to a human. The narrative need not encode all the
structured data, but is required to contain sufficient detail to make it &quot;clinically
safe&quot; for a human to just read the narrative. Resource definitions may define what
content should be represented in the narrative to ensure clinical safety.">text</a>,
<ahref="domainresource.html#DomainResource" title="These resources do not have an independent existence apart from the resource that contains
them - they cannot be identified independently, and nor can they have their own independent
transaction scope.">contained</a>,
<ahref="domainresource.html#DomainResource" title="May be used to represent additional information that is not part of the basic definition
of the resource. To make the use of extensions safe and manageable, there is a strict
set of governance applied to the definition and use of extensions. Though any implementer
can define an extension, there is a set of requirements that SHALL be met as part of the
definition of the extension.">extension</a>,
<ahref="domainresource.html#DomainResource" title="May be used to represent additional information that is not part of the basic definition
of the resource and that modifies the understanding of the element that contains it and/or
the understanding of the containing element's descendants. Usually modifier elements provide
negation or qualification. To make the use of extensions safe and manageable, there is
a strict set of governance applied to the definition and use of extensions. Though any
implementer is allowed to define an extension, there is a set of requirements that SHALL
be met as part of the definition of the extension. Applications processing a resource
are required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource
(including cannot change the meaning of modifierExtension itself).">modifierExtension</a></td></tr><trstyle="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;"><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVB
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VResrjoTPDzdcoU+F65CduVU6KAhhQa3F8Tx8nchBoYuqoTLZoAKFRIhqGwqJAULFx0GYpBQeChRIR4TJm6KJMhQRUSBAAA7" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/><spantitle="Substance.identifier : Unique identifier for the substance.">identifier</span><aname="Substance.identifier"></a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px"><ahref="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px">0..*</td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px"><ahref="datatypes.html#Identifier">Identifier</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px">Unique identifier
<br/></td></tr><trstyle="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;"><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVBORw0KGg
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RgwAAAABJRU5ErkJggg==" style="background-color: white; background-color: inherit" title="Primitive Data Type"/><spantitle="Substance.status : A code to indicate if the substance is actively used.">status</span><aname="Substance.status"></a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"><ahref="conformance-rules.html#isModifier" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is a modifier element">?!</a><ahref="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px">0..1</td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"><ahref="datatypes.html#code">code</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px">active | inactive | entered-in-error
<br/><ahref="valueset-substance-status.html" title="A code to indicate if the substance is actively used.">FHIRSubstanceStatus</a> (
<ahref="terminologies.html#required" title="To be conformant, the concept in this element SHALL be from the specified value set.">Required</a>)
</td></tr><trstyle="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;"><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVB
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Pvowat8Ivvgq/Pbrvzgq/PguvrgrqN0Gda2evfYm9+7d/rpw9q6e/LSku/Rl/XVl/LSlfrkt+zVqe7Wqv3x1/bNffbOf59wFdS6if
3u0vrqyP3owPvepfXQivDQkO/PkKh9K7STVf779P///wD/ACH5BAEKAH8ALAAAAAAQABAAAAemgH+CgxeFF4OIhBdKGwFChYl/hYw
bdkoBPnaQkosbG3d3VEpSUlonUoY1Gzo6QkI8SrGxWBOFG4uySgY5ZWR3PFy2hnaWZXC/PHcPwkpJk1ShoHcxhQEXSUmtFy6+0iSF
VResrjoTPDzdcoU+F65CduVU6KAhhQa3F8Tx8nchBoYuqoTLZoAKFRIhqGwqJAULFx0GYpBQeChRIR4TJm6KJMhQRUSBAAA7" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/><spantitle="Substance.category : A code that classifies the general type of substance. This is used
for searching, sorting and display purposes.">category</span><aname="Substance.category"></a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px"><ahref="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px">0..*</td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px"><ahref="datatypes.html#CodeableConcept">CodeableConcept</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px">What class/type of substance this is
<br/><ahref="valueset-substance-category.html" title="Category or classification of substance.">Substance Category Codes</a> (
<ahref="terminologies.html#extensible" title="To be conformant, the concept in this element SHALL be from the specified value set if
any of the codes within the value set can apply to the concept being communicated. If
the value set does not cover the concept (based on human review), alternate codings (or,
data type allowing, text) may be included instead.">Extensible</a>)
<br/></td></tr><trstyle="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;"><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVBORw0KGg
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zv3rye3LiPvnv+3MjPDasKiIS/789/3x2f747eXDg+7Mifvu0tu7f+/QkfDTnPXWmPrjsvrjtPbPgrqZW+/QlPz48K2EMv36866OU
Pvowat8Ivvgq/Pbrvzgq/PguvrgrqN0Gda2evfYm9+7d/rpw9q6e/LSku/Rl/XVl/LSlfrkt+zVqe7Wqv3x1/bNffbOf59wFdS6if
3u0vrqyP3owPvepfXQivDQkO/PkKh9K7STVf779P///wD/ACH5BAEKAH8ALAAAAAAQABAAAAemgH+CgxeFF4OIhBdKGwFChYl/hYw
bdkoBPnaQkosbG3d3VEpSUlonUoY1Gzo6QkI8SrGxWBOFG4uySgY5ZWR3PFy2hnaWZXC/PHcPwkpJk1ShoHcxhQEXSUmtFy6+0iSF
VResrjoTPDzdcoU+F65CduVU6KAhhQa3F8Tx8nchBoYuqoTLZoAKFRIhqGwqJAULFx0GYpBQeChRIR4TJm6KJMhQRUSBAAA7" style="background-color: white; background-color: inherit" title="Data Type"/><spantitle="Substance.code : A code (or set of codes) that identify this substance.">code</span><aname="Substance.code"></a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"><ahref="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px">1..1</td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"><ahref="datatypes.html#CodeableConcept">CodeableConcept</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px">What substance this is
<br/><ahref="valueset-substance-code.html" title="Substance codes.">Substance Code</a> (
<ahref="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value set. The
value set merely provides examples of the types of concepts intended to be included.">Example</a>)
</td></tr><trstyle="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;"><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVB
ORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6E
EQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)"><imgalt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwN
dCABMPwMo2ctnoQAAAABJRU5ErkJggg==" style="background-color: inherit"/><imgalt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7
/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" style="background-color: inherit"/><imgalt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARk
lEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvT
RgwAAAABJRU5ErkJggg==" style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type"/><spantitle="Substance.description : A description of the substance - its appearance, handling requirements,
and other usage notes.">description</span><aname="Substance.description"></a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px"><ahref="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px">0..1</td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px"><ahref="datatypes.html#string">string</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px">Textual description of the substance, comments</td></tr><trstyle="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;"><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVBORw0KGg
oAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCs
PVYVAgIJrA/sAAAAASUVORK5CYII=)"><imgalt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwN
dCABMPwMo2ctnoQAAAABJRU5ErkJggg==" style="background-color: inherit"/><imgalt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7
/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" style="background-color: inherit"/><imgalt="." class="hierarchy" src="data:image/png;base64,R0lGODlhEAAQAPQfAOvGUf7ztuvPMf/78/fkl/Pbg+u8Rvjqteu2Pf3zxPz36Pz0z+vTmPzurPvuw/
npofbjquvNefHVduuyN+uuMu3Oafbgjfnqvf/3zv/3xevPi+vRjP/20/bmsP///wD/ACH5BAEKAB8ALAAAAAAQABAAAAVl4CeOZGm
e5qCqqDg8jyVJaz1876DsmAQAgqDgltspMEhMJoMZ4iy6I1AooFCIv+wKybziALVAoAEjYLwDgGIpJhMslgxaLR4/3rMAWoBp32V5
exg8Shl1ckRUQVaMVkQ2kCstKCEAOw==" style="background-color: white; background-color: inherit" title="Element"/><spantitle="Substance.instance : Substance may be used to describe a kind of substance, or a specific
package/container of the substance: an instance.">instance</span><aname="Substance.instance"></a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"><ahref="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px">0..*</td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"><ahref="types.html#BackBoneElement">BackboneElement</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px">If this describes a specific package/container of the substance
<br/></td></tr><trstyle="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;"><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVB
ORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+
5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)"><imgalt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwN
dCABMPwMo2ctnoQAAAABJRU5ErkJggg==" style="background-color: inherit"/><imgalt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv
+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" style="background-color: inherit"/><imgalt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7
/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" style="background-color: inherit"/><imgalt="." class="hierarchy" src="data:image/png;base64,R0lGODlhEAAQAPZ/APrkusOiYvvfqbiXWaV2G+jGhdq1b8GgYf3v1frw3vTUlsWkZNewbcSjY/DQka
d4Hb6dXv3u0f3v1ObEgfPTlerJiP3w1v79+e7OkPrfrfnjuNOtZPrpydaxa+/YrvvdpP779ZxvFPvnwKKBQaFyF/369M2vdaqHRPz
58/HNh/vowufFhfroxO3OkPrluv779tK0e6JzGProwvrow9m4eOnIifPTlPDPkP78+Naxaf3v0/zowfXRi+bFhLWUVv379/rnwPvs
zv3rye3LiPvnv+3MjPDasKiIS/789/3x2f747eXDg+7Mifvu0tu7f+/QkfDTnPXWmPrjsvrjtPbPgrqZW+/QlPz48K2EMv36866OU
Pvowat8Ivvgq/Pbrvzgq/PguvrgrqN0Gda2evfYm9+7d/rpw9q6e/LSku/Rl/XVl/LSlfrkt+zVqe7Wqv3x1/bNffbOf59wFdS6if
3u0vrqyP3owPvepfXQivDQkO/PkKh9K7STVf779P///wD/ACH5BAEKAH8ALAAAAAAQABAAAAemgH+CgxeFF4OIhBdKGwFChYl/hYw
bdkoBPnaQkosbG3d3VEpSUlonUoY1Gzo6QkI8SrGxWBOFG4uySgY5ZWR3PFy2hnaWZXC/PHcPwkpJk1ShoHcxhQEXSUmtFy6+0iSF
VResrjoTPDzdcoU+F65CduVU6KAhhQa3F8Tx8nchBoYuqoTLZoAKFRIhqGwqJAULFx0GYpBQeChRIR4TJm6KJMhQRUSBAAA7" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/><spantitle="Substance.instance.identifier : Identifier associated with the package/container (usually
a label affixed directly).">identifier</span><aname="Substance.instance.identifier"></a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px"><ahref="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px">0..1</td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px"><ahref="datatypes.html#Identifier">Identifier</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px">Identifier of the package/container</td></tr><trstyle="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;"><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVBORw0KGg
oAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOC
ZBkurQFbnaRSlAAAAAElFTkSuQmCC)"><imgalt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwN
dCABMPwMo2ctnoQAAAABJRU5ErkJggg==" style="background-color: inherit"/><imgalt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv
+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" style="background-color: inherit"/><imgalt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7
/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" style="background-color: inherit"/><imgalt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARk
lEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvT
RgwAAAABJRU5ErkJggg==" style="background-color: white; background-color: inherit" title="Primitive Data Type"/><spantitle="Substance.instance.expiry : When the substance is no longer valid to use. For some substances,
a single arbitrary date is used for expiry.">expiry</span><aname="Substance.instance.expiry"></a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"><ahref="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px">0..1</td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"><ahref="datatypes.html#dateTime">dateTime</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px">When no longer valid to use</td></tr><trstyle="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;"><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVB
ORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6E
EQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)"><imgalt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwN
dCABMPwMo2ctnoQAAAABJRU5ErkJggg==" style="background-color: inherit"/><imgalt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv
+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" style="background-color: inherit"/><imgalt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUOL
+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC" style="background-color: inherit"/><imgalt="." class="hierarchy" src="data:image/png;base64,R0lGODlhEAAQAPZ/APrkusOiYvvfqbiXWaV2G+jGhdq1b8GgYf3v1frw3vTUlsWkZNewbcSjY/DQka
d4Hb6dXv3u0f3v1ObEgfPTlerJiP3w1v79+e7OkPrfrfnjuNOtZPrpydaxa+/YrvvdpP779ZxvFPvnwKKBQaFyF/369M2vdaqHRPz
58/HNh/vowufFhfroxO3OkPrluv779tK0e6JzGProwvrow9m4eOnIifPTlPDPkP78+Naxaf3v0/zowfXRi+bFhLWUVv379/rnwPvs
zv3rye3LiPvnv+3MjPDasKiIS/789/3x2f747eXDg+7Mifvu0tu7f+/QkfDTnPXWmPrjsvrjtPbPgrqZW+/QlPz48K2EMv36866OU
Pvowat8Ivvgq/Pbrvzgq/PguvrgrqN0Gda2evfYm9+7d/rpw9q6e/LSku/Rl/XVl/LSlfrkt+zVqe7Wqv3x1/bNffbOf59wFdS6if
3u0vrqyP3owPvepfXQivDQkO/PkKh9K7STVf779P///wD/ACH5BAEKAH8ALAAAAAAQABAAAAemgH+CgxeFF4OIhBdKGwFChYl/hYw
bdkoBPnaQkosbG3d3VEpSUlonUoY1Gzo6QkI8SrGxWBOFG4uySgY5ZWR3PFy2hnaWZXC/PHcPwkpJk1ShoHcxhQEXSUmtFy6+0iSF
VResrjoTPDzdcoU+F65CduVU6KAhhQa3F8Tx8nchBoYuqoTLZoAKFRIhqGwqJAULFx0GYpBQeChRIR4TJm6KJMhQRUSBAAA7" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/><spantitle="Substance.instance.quantity : The amount of the substance.">quantity</span><aname="Substance.instance.quantity"></a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px"><ahref="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px">0..1</td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px"><ahref="datatypes.html#SimpleQuantity">SimpleQuantity</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px">Amount of substance in the package</td></tr><trstyle="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;"><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVBORw0KGg
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exg8Shl1ckRUQVaMVkQ2kCstKCEAOw==" style="background-color: white; background-color: inherit" title="Element"/><spantitle="Substance.ingredient : A substance can be composed of other substances.">ingredient</span><aname="Substance.ingredient"></a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"><ahref="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px">0..*</td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"><ahref="types.html#BackBoneElement">BackboneElement</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px">Composition information about the substance
<br/></td></tr><trstyle="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;"><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVB
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bdkoBPnaQkosbG3d3VEpSUlonUoY1Gzo6QkI8SrGxWBOFG4uySgY5ZWR3PFy2hnaWZXC/PHcPwkpJk1ShoHcxhQEXSUmtFy6+0iSF
VResrjoTPDzdcoU+F65CduVU6KAhhQa3F8Tx8nchBoYuqoTLZoAKFRIhqGwqJAULFx0GYpBQeChRIR4TJm6KJMhQRUSBAAA7" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/><spantitle="Substance.ingredient.quantity : The amount of the ingredient in the substance - a concentration
ratio.">quantity</span><aname="Substance.ingredient.quantity"></a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px"><ahref="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px">0..1</td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px"><ahref="datatypes.html#Ratio">Ratio</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px">Optional amount (concentration)</td></tr><trstyle="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;"><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVBORw0KGg
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padding:0px 4px 0px 4px"><ahref="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px">1..1</td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"/><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px">A component of the substance
<br/><ahref="valueset-substance-code.html" title="Substance Ingredient codes.">Substance Code</a> (
<ahref="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value set. The
value set merely provides examples of the types of concepts intended to be included.">Example</a>)
</td></tr><trstyle="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;"><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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be provided by text.">substanceCodeableConcept</span></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px"/><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px"/><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px"><ahref="datatypes.html#CodeableConcept">CodeableConcept</a></td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
solid; padding:0px 4px 0px 4px"/></tr><trstyle="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;"><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVBORw0KGg
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lQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC" style="background-color: white; background-color: inherit" title="Reference to another Resource"/> substanceReference
</td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"/><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"/><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"><ahref="references.html#Reference">Reference</a>(
<ahref="substance.html">Substance</a>)
</td><tdclass="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
padding:0px 4px 0px 4px"/></tr><tr><tdclass="hierarchy" colspan="5"><br/><ahref="formats.html#table" title="Legend for this format"><imgalt="doco" src="help16.png" style="background-color: inherit"/> Documentation for this format
</a></td></tr></table></div></text><extensionurl="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"><valueCodevalue="trial-use"/></extension><extensionurl="http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm"><valueIntegervalue="2"/></extension><extensionurl="http://hl7.org/fhir/StructureDefinition/structuredefinition-security-category"><valueCodevalue="business"/></extension><extensionurl="http://hl7.org/fhir/StructureDefinition/structuredefinition-wg"><valueCodevalue="oo"/></extension><urlvalue="http://hl7.org/fhir/StructureDefinition/Substance"/><versionvalue="4.4.0"/><namevalue="Substance"/><statusvalue="draft"/><datevalue="2020-06-06T02:25:40+00:00"/><publishervalue="Health Level Seven International (Orders and Observations)"/><contact><telecom><systemvalue="url"/><valuevalue="http://hl7.org/fhir"/></telecom></contact><contact><telecom><systemvalue="url"/><valuevalue="http://www.hl7.org/Special/committees/orders/index.cfm"/></telecom></contact><descriptionvalue="A homogeneous material with a definite composition."/><fhirVersionvalue="4.4.0"/><mapping><identityvalue="rim"/><urivalue="http://hl7.org/v3"/><namevalue="RIM Mapping"/></mapping><mapping><identityvalue="orim"/><urivalue="http://hl7.org/orim"/><namevalue="Ontological RIM Mapping"/></mapping><mapping><identityvalue="w5"/><urivalue="http://hl7.org/fhir/fivews"/><namevalue="FiveWs Pattern Mapping"/></mapping><kindvalue="resource"/><abstractvalue="false"/><typevalue="Substance"/><baseDefinitionvalue="http://hl7.org/fhir/StructureDefinition/DomainResource"/><derivationvalue="specialization"/><snapshot><elementid="Substance"><pathvalue="Substance"/><shortvalue="A homogeneous material with a definite composition"/><definitionvalue="A homogeneous material with a definite composition."/><minvalue="0"/><maxvalue="*"/><base><pathvalue="Substance"/><minvalue="0"/><maxvalue="*"/></base><constraint><keyvalue="dom-2"/><severityvalue="error"/><humanvalue="If the resource is contained in another resource, it SHALL NOT contain nested Resources"/><expressionvalue="contained.contained.empty()"/><xpathvalue="not(parent::f:contained and f:contained)"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/DomainResource"/></constraint><constraint><keyvalue="dom-3"/><severityvalue="error"/><humanvalue="If the resource is contained in another resource, it SHALL be referred to from elsewhere
in the resource or SHALL refer to the containing resource"/><expressionvalue="contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonica
l) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(refer
ence = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(c
anonical) = '#').exists()).not()).trace('unmatched', id).empty()"/><xpathvalue="not(exists(for $id in f:contained/*/f:id/@value return $contained[not(parent::*/descendant::f:refere
nce/@value=concat('#', $contained/*/id/@value) or descendant::f:reference[@value='#'])]))"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/DomainResource"/></constraint><constraint><keyvalue="dom-4"/><severityvalue="error"/><humanvalue="If a resource is contained in another resource, it SHALL NOT have a meta.versionId or
a meta.lastUpdated"/><expressionvalue="contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()"/><xpathvalue="not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/DomainResource"/></constraint><constraint><keyvalue="dom-5"/><severityvalue="error"/><humanvalue="If a resource is contained in another resource, it SHALL NOT have a security label"/><expressionvalue="contained.meta.security.empty()"/><xpathvalue="not(exists(f:contained/*/f:meta/f:security))"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/DomainResource"/></constraint><constraint><extensionurl="http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice"><valueBooleanvalue="true"/></extension><extensionurl="http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation"><valueMarkdownvalue="When a resource has no narrative, only systems that fully understand the data can display
the resource to a human safely. Including a human readable representation in the resource
makes for a much more robust eco-system and cheaper handling of resources by intermediary
systems. Some ecosystems restrict distribution of resources to only those systems that
do fully understand the resources, and as a consequence implementers may believe that
the narrative is superfluous. However experience shows that such eco-systems often open
up to new participants over time."/></extension><keyvalue="dom-6"/><severityvalue="warning"/><humanvalue="A resource should have narrative for robust management"/><expressionvalue="text.`div`.exists()"/><xpathvalue="exists(f:text/h:div)"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/DomainResource"/></constraint><isModifiervalue="false"/><isSummaryvalue="false"/><mapping><identityvalue="rim"/><mapvalue="Entity. Role, or Act"/></mapping><mapping><identityvalue="rim"/><mapvalue="Material"/></mapping><mapping><identityvalue="orim"/><mapvalue="fhir:Substance rdfs:subClassOf rim:Entity, [ a owl:Restriction; owl:onProperty
rim:Act.classCode; owl:allValuesFrom cs:EntityClass\#MAT ]."/></mapping></element><elementid="Substance.id"><pathvalue="Substance.id"/><shortvalue="Logical id of this artifact"/><definitionvalue="The logical id of the resource, as used in the URL for the resource. Once assigned, this
value never changes."/><commentvalue="The only time that a resource does not have an id is when it is being submitted to the
server using a create operation."/><minvalue="0"/><maxvalue="1"/><base><pathvalue="Resource.id"/><minvalue="0"/><maxvalue="1"/></base><!-- Note: special primitive values have a FHIRPath system type. e.g. this is compiler magic
(j) --><type><extensionurl="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"><valueUrivalue="id"/></extension><codevalue="http://hl7.org/fhirpath/System.String"/></type><isModifiervalue="false"/><isSummaryvalue="true"/></element><elementid="Substance.meta"><pathvalue="Substance.meta"/><shortvalue="Metadata about the resource"/><definitionvalue="The metadata about the resource. This is content that is maintained by the infrastructure.
Changes to the content might not always be associated with version changes to the resource."/><minvalue="0"/><maxvalue="1"/><base><pathvalue="Resource.meta"/><minvalue="0"/><maxvalue="1"/></base><type><codevalue="Meta"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><isModifiervalue="false"/><isSummaryvalue="true"/></element><elementid="Substance.implicitRules"><pathvalue="Substance.implicitRules"/><shortvalue="A set of rules under which this content was created"/><definitionvalue="A reference to a set of rules that were followed when the resource was constructed, and
which must be understood when processing the content. Often, this is a reference to an
implementation guide that defines the special rules along with other profiles etc."/><commentvalue="Asserting this rule set restricts the content to be only understood by a limited set of
trading partners. This inherently limits the usefulness of the data in the long term.
However, the existing health eco-system is highly fractured, and not yet ready to define,
collect, and exchange data in a generally computable sense. Wherever possible, implementers
and/or specification writers should avoid using this element. Often, when used, the URL
is a reference to an implementation guide that defines these special rules as part of
it's narrative along with other profiles, value sets, etc."/><minvalue="0"/><maxvalue="1"/><base><pathvalue="Resource.implicitRules"/><minvalue="0"/><maxvalue="1"/></base><type><codevalue="uri"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><isModifiervalue="true"/><isModifierReasonvalue="This element is labeled as a modifier because the implicit rules may provide additional
knowledge about the resource that modifies it's meaning or interpretation"/><isSummaryvalue="true"/></element><elementid="Substance.language"><pathvalue="Substance.language"/><shortvalue="Language of the resource content"/><definitionvalue="The base language in which the resource is written."/><commentvalue="Language is provided to support indexing and accessibility (typically, services such as
text to speech use the language tag). The html language tag in the narrative applies
to the narrative. The language tag on the resource may be used to specify the language
of other presentations generated from the data in the resource. Not all the content has
to be in the base language. The Resource.language should not be assumed to apply to the
narrative automatically. If a language is specified, it should it also be specified on
the div element in the html (see rules in HTML5 for information about the relationship
between xml:lang and the html lang attribute)."/><minvalue="0"/><maxvalue="1"/><base><pathvalue="Resource.language"/><minvalue="0"/><maxvalue="1"/></base><type><codevalue="code"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><isModifiervalue="false"/><isSummaryvalue="false"/><binding><extensionurl="http://hl7.org/fhir/StructureDefinition/elementdefinition-maxValueSet"><valueCanonicalvalue="http://hl7.org/fhir/ValueSet/all-languages"/></extension><extensionurl="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"><valueStringvalue="Language"/></extension><extensionurl="http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding"><valueBooleanvalue="true"/></extension><strengthvalue="preferred"/><descriptionvalue="A human language."/><valueSetvalue="http://hl7.org/fhir/ValueSet/languages"/></binding></element><elementid="Substance.text"><pathvalue="Substance.text"/><shortvalue="Text summary of the resource, for human interpretation"/><definitionvalue="A human-readable narrative that contains a summary of the resource and can be used to
represent the content of the resource to a human. The narrative need not encode all the
structured data, but is required to contain sufficient detail to make it &quot;clinically
safe&quot; for a human to just read the narrative. Resource definitions may define what
content should be represented in the narrative to ensure clinical safety."/><commentvalue="Contained resources do not have narrative. Resources that are not contained SHOULD have
a narrative. In some cases, a resource may only have text with little or no additional
discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary
for data from legacy systems where information is captured as a &quot;text blob&quot;
or where text is additionally entered raw or narrated and encoded information is added
later."/><aliasvalue="narrative"/><aliasvalue="html"/><aliasvalue="xhtml"/><aliasvalue="display"/><minvalue="0"/><maxvalue="1"/><base><pathvalue="DomainResource.text"/><minvalue="0"/><maxvalue="1"/></base><type><codevalue="Narrative"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><isModifiervalue="false"/><isSummaryvalue="false"/><mapping><identityvalue="rim"/><mapvalue="Act.text?"/></mapping></element><elementid="Substance.contained"><pathvalue="Substance.contained"/><shortvalue="Contained, inline Resources"/><definitionvalue="These resources do not have an independent existence apart from the resource that contains
them - they cannot be identified independently, and nor can they have their own independent
transaction scope."/><commentvalue="This should never be done when the content can be identified properly, as once identification
is lost, it is extremely difficult (and context dependent) to restore it again. Contained
resources may have profiles and tags In their meta elements, but SHALL NOT have security
labels."/><aliasvalue="inline resources"/><aliasvalue="anonymous resources"/><aliasvalue="contained resources"/><minvalue="0"/><maxvalue="*"/><base><pathvalue="DomainResource.contained"/><minvalue="0"/><maxvalue="*"/></base><type><codevalue="Resource"/></type><isModifiervalue="false"/><isSummaryvalue="false"/><mapping><identityvalue="rim"/><mapvalue="N/A"/></mapping></element><elementid="Substance.extension"><pathvalue="Substance.extension"/><shortvalue="Additional content defined by implementations"/><definitionvalue="May be used to represent additional information that is not part of the basic definition
of the resource. To make the use of extensions safe and manageable, there is a strict
set of governance applied to the definition and use of extensions. Though any implementer
can define an extension, there is a set of requirements that SHALL be met as part of the
definition of the extension."/><commentvalue="There can be no stigma associated with the use of extensions by any application, project,
or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
The use of extensions is what allows the FHIR specification to retain a core level of
simplicity for everyone."/><aliasvalue="extensions"/><aliasvalue="user content"/><minvalue="0"/><maxvalue="*"/><base><pathvalue="DomainResource.extension"/><minvalue="0"/><maxvalue="*"/></base><type><codevalue="Extension"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><constraint><keyvalue="ext-1"/><severityvalue="error"/><humanvalue="Must have either extensions or value[x], not both"/><expressionvalue="extension.exists() != value.exists()"/><xpathvalue="exists(f:extension)!=exists(f:*[starts-with(local-name(.), &quot;value&quot;)])"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Extension"/></constraint><isModifiervalue="false"/><isSummaryvalue="false"/><mapping><identityvalue="rim"/><mapvalue="N/A"/></mapping></element><elementid="Substance.modifierExtension"><pathvalue="Substance.modifierExtension"/><shortvalue="Extensions that cannot be ignored"/><definitionvalue="May be used to represent additional information that is not part of the basic definition
of the resource and that modifies the understanding of the element that contains it and/or
the understanding of the containing element's descendants. Usually modifier elements provide
negation or qualification. To make the use of extensions safe and manageable, there is
a strict set of governance applied to the definition and use of extensions. Though any
implementer is allowed to define an extension, there is a set of requirements that SHALL
be met as part of the definition of the extension. Applications processing a resource
are required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource
(including cannot change the meaning of modifierExtension itself)."/><commentvalue="There can be no stigma associated with the use of extensions by any application, project,
or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
The use of extensions is what allows the FHIR specification to retain a core level of
simplicity for everyone."/><requirementsvalue="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly
distinguished from the vast majority of extensions which can be safely ignored. This
promotes interoperability by eliminating the need for implementers to prohibit the presence
of extensions. For further information, see the [definition of modifier extensions](extensibility.ht
ml#modifierExtension)."/><aliasvalue="extensions"/><aliasvalue="user content"/><minvalue="0"/><maxvalue="*"/><base><pathvalue="DomainResource.modifierExtension"/><minvalue="0"/><maxvalue="*"/></base><type><codevalue="Extension"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><constraint><keyvalue="ext-1"/><severityvalue="error"/><humanvalue="Must have either extensions or value[x], not both"/><expressionvalue="extension.exists() != value.exists()"/><xpathvalue="exists(f:extension)!=exists(f:*[starts-with(local-name(.), &quot;value&quot;)])"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Extension"/></constraint><isModifiervalue="true"/><isModifierReasonvalue="Modifier extensions are expected to modify the meaning or interpretation of the resource
that contains them"/><isSummaryvalue="false"/><mapping><identityvalue="rim"/><mapvalue="N/A"/></mapping></element><elementid="Substance.identifier"><pathvalue="Substance.identifier"/><shortvalue="Unique identifier"/><definitionvalue="Unique identifier for the substance."/><commentvalue="This identifier is associated with the kind of substance in contrast to the Substance.instance.iden
tifier which is associated with the package/container."/><minvalue="0"/><maxvalue="*"/><base><pathvalue="Substance.identifier"/><minvalue="0"/><maxvalue="*"/></base><type><codevalue="Identifier"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><isModifiervalue="false"/><isSummaryvalue="true"/><mapping><identityvalue="w5"/><mapvalue="FiveWs.identifier"/></mapping><mapping><identityvalue="rim"/><mapvalue=".id"/></mapping></element><elementid="Substance.status"><pathvalue="Substance.status"/><shortvalue="active | inactive | entered-in-error"/><definitionvalue="A code to indicate if the substance is actively used."/><minvalue="0"/><maxvalue="1"/><base><pathvalue="Substance.status"/><minvalue="0"/><maxvalue="1"/></base><type><codevalue="code"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><isModifiervalue="true"/><isModifierReasonvalue="This element is labelled as a modifier because it is a status element that contains status
entered-in-error which means that the resource should not be treated as valid"/><isSummaryvalue="true"/><binding><extensionurl="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"><valueStringvalue="FHIRSubstanceStatus"/></extension><strengthvalue="required"/><descriptionvalue="A code to indicate if the substance is actively used."/><valueSetvalue="http://hl7.org/fhir/ValueSet/substance-status|4.4.0"/></binding><mapping><identityvalue="w5"/><mapvalue="FiveWs.status"/></mapping><mapping><identityvalue="rim"/><mapvalue=".statusCode"/></mapping></element><elementid="Substance.category"><pathvalue="Substance.category"/><shortvalue="What class/type of substance this is"/><definitionvalue="A code that classifies the general type of substance. This is used for searching, sorting
and display purposes."/><commentvalue="The level of granularity is defined by the category concepts in the value set. More
fine-grained filtering can be performed using the metadata and/or terminology hierarchy
in Substance.code."/><minvalue="0"/><maxvalue="*"/><base><pathvalue="Substance.category"/><minvalue="0"/><maxvalue="*"/></base><type><codevalue="CodeableConcept"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><isModifiervalue="false"/><isSummaryvalue="true"/><binding><extensionurl="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"><valueStringvalue="SubstanceCategory"/></extension><strengthvalue="extensible"/><descriptionvalue="Category or classification of substance."/><valueSetvalue="http://hl7.org/fhir/ValueSet/substance-category"/></binding><mapping><identityvalue="w5"/><mapvalue="FiveWs.class"/></mapping><mapping><identityvalue="rim"/><mapvalue=".code"/></mapping></element><elementid="Substance.code"><pathvalue="Substance.code"/><shortvalue="What substance this is"/><definitionvalue="A code (or set of codes) that identify this substance."/><commentvalue="This could be a reference to an externally defined code. It could also be a locally assigned
code (e.g. a formulary), optionally with translations to the standard drug codes."/><minvalue="1"/><maxvalue="1"/><base><pathvalue="Substance.code"/><minvalue="1"/><maxvalue="1"/></base><type><codevalue="CodeableConcept"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><isModifiervalue="false"/><isSummaryvalue="true"/><binding><extensionurl="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"><valueStringvalue="SubstanceCode"/></extension><strengthvalue="example"/><descriptionvalue="Substance codes."/><valueSetvalue="http://hl7.org/fhir/ValueSet/substance-code"/></binding><mapping><identityvalue="w5"/><mapvalue="FiveWs.what[x]"/></mapping><mapping><identityvalue="rim"/><mapvalue=".code"/></mapping><mapping><identityvalue="orim"/><mapvalue="fhir:Substance.code rdfs:subPropertyOf rim:Entity.code"/></mapping></element><elementid="Substance.description"><pathvalue="Substance.description"/><shortvalue="Textual description of the substance, comments"/><definitionvalue="A description of the substance - its appearance, handling requirements, and other usage
notes."/><minvalue="0"/><maxvalue="1"/><base><pathvalue="Substance.description"/><minvalue="0"/><maxvalue="1"/></base><type><codevalue="string"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><isModifiervalue="false"/><isSummaryvalue="true"/><mapping><identityvalue="rim"/><mapvalue=".player.desc"/></mapping></element><elementid="Substance.instance"><pathvalue="Substance.instance"/><shortvalue="If this describes a specific package/container of the substance"/><definitionvalue="Substance may be used to describe a kind of substance, or a specific package/container
of the substance: an instance."/><minvalue="0"/><maxvalue="*"/><base><pathvalue="Substance.instance"/><minvalue="0"/><maxvalue="*"/></base><type><codevalue="BackboneElement"/></type><meaningWhenMissingvalue="If this element is not present, then the substance resource describes a kind of substance"/><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><isModifiervalue="false"/><isSummaryvalue="true"/><mapping><identityvalue="rim"/><mapvalue=".player.determinerCode"/></mapping></element><elementid="Substance.instance.id"><pathvalue="Substance.instance.id"/><representationvalue="xmlAttr"/><shortvalue="Unique id for inter-element referencing"/><definitionvalue="Unique id for the element within a resource (for internal references). This may be any
string value that does not contain spaces."/><minvalue="0"/><maxvalue="1"/><base><pathvalue="Element.id"/><minvalue="0"/><maxvalue="1"/></base><!-- Note: special primitive values have a FHIRPath system type. e.g. this is compiler magic
(j) --><type><extensionurl="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"><valueUrivalue="id"/></extension><codevalue="http://hl7.org/fhirpath/System.String"/></type><isModifiervalue="false"/><isSummaryvalue="false"/><mapping><identityvalue="rim"/><mapvalue="n/a"/></mapping></element><elementid="Substance.instance.extension"><pathvalue="Substance.instance.extension"/><shortvalue="Additional content defined by implementations"/><definitionvalue="May be used to represent additional information that is not part of the basic definition
of the element. To make the use of extensions safe and manageable, there is a strict set
of governance applied to the definition and use of extensions. Though any implementer
can define an extension, there is a set of requirements that SHALL be met as part of the
definition of the extension."/><commentvalue="There can be no stigma associated with the use of extensions by any application, project,
or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
The use of extensions is what allows the FHIR specification to retain a core level of
simplicity for everyone."/><aliasvalue="extensions"/><aliasvalue="user content"/><minvalue="0"/><maxvalue="*"/><base><pathvalue="Element.extension"/><minvalue="0"/><maxvalue="*"/></base><type><codevalue="Extension"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><constraint><keyvalue="ext-1"/><severityvalue="error"/><humanvalue="Must have either extensions or value[x], not both"/><expressionvalue="extension.exists() != value.exists()"/><xpathvalue="exists(f:extension)!=exists(f:*[starts-with(local-name(.), &quot;value&quot;)])"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Extension"/></constraint><isModifiervalue="false"/><isSummaryvalue="false"/><mapping><identityvalue="rim"/><mapvalue="n/a"/></mapping></element><elementid="Substance.instance.modifierExtension"><pathvalue="Substance.instance.modifierExtension"/><shortvalue="Extensions that cannot be ignored even if unrecognized"/><definitionvalue="May be used to represent additional information that is not part of the basic definition
of the element and that modifies the understanding of the element in which it is contained
and/or the understanding of the containing element's descendants. Usually modifier elements
provide negation or qualification. To make the use of extensions safe and manageable,
there is a strict set of governance applied to the definition and use of extensions. Though
any implementer can define an extension, there is a set of requirements that SHALL be
met as part of the definition of the extension. Applications processing a resource are
required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource
(including cannot change the meaning of modifierExtension itself)."/><commentvalue="There can be no stigma associated with the use of extensions by any application, project,
or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
The use of extensions is what allows the FHIR specification to retain a core level of
simplicity for everyone."/><requirementsvalue="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly
distinguished from the vast majority of extensions which can be safely ignored. This
promotes interoperability by eliminating the need for implementers to prohibit the presence
of extensions. For further information, see the [definition of modifier extensions](extensibility.ht
ml#modifierExtension)."/><aliasvalue="extensions"/><aliasvalue="user content"/><aliasvalue="modifiers"/><minvalue="0"/><maxvalue="*"/><base><pathvalue="BackboneElement.modifierExtension"/><minvalue="0"/><maxvalue="*"/></base><type><codevalue="Extension"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><constraint><keyvalue="ext-1"/><severityvalue="error"/><humanvalue="Must have either extensions or value[x], not both"/><expressionvalue="extension.exists() != value.exists()"/><xpathvalue="exists(f:extension)!=exists(f:*[starts-with(local-name(.), &quot;value&quot;)])"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Extension"/></constraint><isModifiervalue="true"/><isModifierReasonvalue="Modifier extensions are expected to modify the meaning or interpretation of the element
that contains them"/><isSummaryvalue="true"/><mapping><identityvalue="rim"/><mapvalue="N/A"/></mapping></element><elementid="Substance.instance.identifier"><pathvalue="Substance.instance.identifier"/><shortvalue="Identifier of the package/container"/><definitionvalue="Identifier associated with the package/container (usually a label affixed directly)."/><minvalue="0"/><maxvalue="1"/><base><pathvalue="Substance.instance.identifier"/><minvalue="0"/><maxvalue="1"/></base><type><codevalue="Identifier"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><isModifiervalue="false"/><isSummaryvalue="true"/><mapping><identityvalue="rim"/><mapvalue=".id"/></mapping></element><elementid="Substance.instance.expiry"><pathvalue="Substance.instance.expiry"/><shortvalue="When no longer valid to use"/><definitionvalue="When the substance is no longer valid to use. For some substances, a single arbitrary
date is used for expiry."/><minvalue="0"/><maxvalue="1"/><base><pathvalue="Substance.instance.expiry"/><minvalue="0"/><maxvalue="1"/></base><type><codevalue="dateTime"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><isModifiervalue="false"/><isSummaryvalue="true"/><mapping><identityvalue="rim"/><mapvalue=".expiryTime"/></mapping></element><elementid="Substance.instance.quantity"><pathvalue="Substance.instance.quantity"/><shortvalue="Amount of substance in the package"/><definitionvalue="The amount of the substance."/><minvalue="0"/><maxvalue="1"/><base><pathvalue="Substance.instance.quantity"/><minvalue="0"/><maxvalue="1"/></base><type><codevalue="Quantity"/><profilevalue="http://hl7.org/fhir/StructureDefinition/SimpleQuantity"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><isModifiervalue="false"/><isSummaryvalue="true"/><mapping><identityvalue="rim"/><mapvalue=".player.quantity"/></mapping></element><elementid="Substance.ingredient"><pathvalue="Substance.ingredient"/><shortvalue="Composition information about the substance"/><definitionvalue="A substance can be composed of other substances."/><minvalue="0"/><maxvalue="*"/><base><pathvalue="Substance.ingredient"/><minvalue="0"/><maxvalue="*"/></base><type><codevalue="BackboneElement"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><isModifiervalue="false"/><isSummaryvalue="true"/><mapping><identityvalue="rim"/><mapvalue=".player.scopesRole[classCode=INGR]"/></mapping></element><elementid="Substance.ingredient.id"><pathvalue="Substance.ingredient.id"/><representationvalue="xmlAttr"/><shortvalue="Unique id for inter-element referencing"/><definitionvalue="Unique id for the element within a resource (for internal references). This may be any
string value that does not contain spaces."/><minvalue="0"/><maxvalue="1"/><base><pathvalue="Element.id"/><minvalue="0"/><maxvalue="1"/></base><!-- Note: special primitive values have a FHIRPath system type. e.g. this is compiler magic
(j) --><type><extensionurl="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"><valueUrivalue="id"/></extension><codevalue="http://hl7.org/fhirpath/System.String"/></type><isModifiervalue="false"/><isSummaryvalue="false"/><mapping><identityvalue="rim"/><mapvalue="n/a"/></mapping></element><elementid="Substance.ingredient.extension"><pathvalue="Substance.ingredient.extension"/><shortvalue="Additional content defined by implementations"/><definitionvalue="May be used to represent additional information that is not part of the basic definition
of the element. To make the use of extensions safe and manageable, there is a strict set
of governance applied to the definition and use of extensions. Though any implementer
can define an extension, there is a set of requirements that SHALL be met as part of the
definition of the extension."/><commentvalue="There can be no stigma associated with the use of extensions by any application, project,
or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
The use of extensions is what allows the FHIR specification to retain a core level of
simplicity for everyone."/><aliasvalue="extensions"/><aliasvalue="user content"/><minvalue="0"/><maxvalue="*"/><base><pathvalue="Element.extension"/><minvalue="0"/><maxvalue="*"/></base><type><codevalue="Extension"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><constraint><keyvalue="ext-1"/><severityvalue="error"/><humanvalue="Must have either extensions or value[x], not both"/><expressionvalue="extension.exists() != value.exists()"/><xpathvalue="exists(f:extension)!=exists(f:*[starts-with(local-name(.), &quot;value&quot;)])"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Extension"/></constraint><isModifiervalue="false"/><isSummaryvalue="false"/><mapping><identityvalue="rim"/><mapvalue="n/a"/></mapping></element><elementid="Substance.ingredient.modifierExtension"><pathvalue="Substance.ingredient.modifierExtension"/><shortvalue="Extensions that cannot be ignored even if unrecognized"/><definitionvalue="May be used to represent additional information that is not part of the basic definition
of the element and that modifies the understanding of the element in which it is contained
and/or the understanding of the containing element's descendants. Usually modifier elements
provide negation or qualification. To make the use of extensions safe and manageable,
there is a strict set of governance applied to the definition and use of extensions. Though
any implementer can define an extension, there is a set of requirements that SHALL be
met as part of the definition of the extension. Applications processing a resource are
required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource
(including cannot change the meaning of modifierExtension itself)."/><commentvalue="There can be no stigma associated with the use of extensions by any application, project,
or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
The use of extensions is what allows the FHIR specification to retain a core level of
simplicity for everyone."/><requirementsvalue="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly
distinguished from the vast majority of extensions which can be safely ignored. This
promotes interoperability by eliminating the need for implementers to prohibit the presence
of extensions. For further information, see the [definition of modifier extensions](extensibility.ht
ml#modifierExtension)."/><aliasvalue="extensions"/><aliasvalue="user content"/><aliasvalue="modifiers"/><minvalue="0"/><maxvalue="*"/><base><pathvalue="BackboneElement.modifierExtension"/><minvalue="0"/><maxvalue="*"/></base><type><codevalue="Extension"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><constraint><keyvalue="ext-1"/><severityvalue="error"/><humanvalue="Must have either extensions or value[x], not both"/><expressionvalue="extension.exists() != value.exists()"/><xpathvalue="exists(f:extension)!=exists(f:*[starts-with(local-name(.), &quot;value&quot;)])"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Extension"/></constraint><isModifiervalue="true"/><isModifierReasonvalue="Modifier extensions are expected to modify the meaning or interpretation of the element
that contains them"/><isSummaryvalue="true"/><mapping><identityvalue="rim"/><mapvalue="N/A"/></mapping></element><elementid="Substance.ingredient.quantity"><pathvalue="Substance.ingredient.quantity"/><shortvalue="Optional amount (concentration)"/><definitionvalue="The amount of the ingredient in the substance - a concentration ratio."/><minvalue="0"/><maxvalue="1"/><base><pathvalue="Substance.ingredient.quantity"/><minvalue="0"/><maxvalue="1"/></base><type><codevalue="Ratio"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><isModifiervalue="false"/><isSummaryvalue="true"/><mapping><identityvalue="rim"/><mapvalue=".quantity"/></mapping></element><elementid="Substance.ingredient.substance[x]"><pathvalue="Substance.ingredient.substance[x]"/><shortvalue="A component of the substance"/><definitionvalue="Another substance that is a component of this substance."/><minvalue="1"/><maxvalue="1"/><base><pathvalue="Substance.ingredient.substance[x]"/><minvalue="1"/><maxvalue="1"/></base><type><codevalue="CodeableConcept"/></type><type><codevalue="Reference"/><targetProfilevalue="http://hl7.org/fhir/StructureDefinition/Substance"/></type><constraint><keyvalue="ele-1"/><severityvalue="error"/><humanvalue="All FHIR elements must have a @value or children"/><expressionvalue="hasValue() or (children().count() &gt; id.count())"/><xpathvalue="@value|f:*|h:div"/><sourcevalue="http://hl7.org/fhir/StructureDefinition/Element"/></constraint><isModifiervalue="false"/><isSummaryvalue="true"/><binding><extensionurl="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"><valueStringvalue="SubstanceIngredient"/></extension><strengthvalue="example"/><descriptionvalue="Substance Ingredient codes."/><valueSetvalue="http://hl7.org/fhir/ValueSet/substance-code"/></binding><mapping><identityvalue="rim"/><mapvalue=".player"/></mapping></element></snapshot><differential><elementid="Substance"><pathvalue="Substance"/><shortvalue="A homogeneous material with a definite composition"/><definitionvalue="A homogeneous material with a definite composition."/><minvalue="0"/><maxvalue="*"/><mapping><identityvalue="rim"/><mapvalue="Material"/></mapping><mapping><identityvalue="orim"/><mapvalue="fhir:Substance rdfs:subClassOf rim:Entity, [ a owl:Restriction; owl:onProperty
rim:Act.classCode; owl:allValuesFrom cs:EntityClass\#MAT ]."/></mapping></element><elementid="Substance.identifier"><pathvalue="Substance.identifier"/><shortvalue="Unique identifier"/><definitionvalue="Unique identifier for the substance."/><commentvalue="This identifier is associated with the kind of substance in contrast to the Substance.instance.iden
tifier which is associated with the package/container."/><minvalue="0"/><maxvalue="*"/><type><codevalue="Identifier"/></type><isSummaryvalue="true"/><mapping><identityvalue="w5"/><mapvalue="FiveWs.identifier"/></mapping><mapping><identityvalue="rim"/><mapvalue=".id"/></mapping></element><elementid="Substance.status"><pathvalue="Substance.status"/><shortvalue="active | inactive | entered-in-error"/><definitionvalue="A code to indicate if the substance is actively used."/><minvalue="0"/><maxvalue="1"/><type><codevalue="code"/></type><isModifiervalue="true"/><isModifierReasonvalue="This element is labelled as a modifier because it is a status element that contains status
entered-in-error which means that the resource should not be treated as valid"/><isSummaryvalue="true"/><binding><extensionurl="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"><valueStringvalue="FHIRSubstanceStatus"/></extension><strengthvalue="required"/><descriptionvalue="A code to indicate if the substance is actively used."/><valueSetvalue="http://hl7.org/fhir/ValueSet/substance-status|4.4.0"/></binding><mapping><identityvalue="w5"/><mapvalue="FiveWs.status"/></mapping><mapping><identityvalue="rim"/><mapvalue=".statusCode"/></mapping></element><elementid="Substance.category"><pathvalue="Substance.category"/><shortvalue="What class/type of substance this is"/><definitionvalue="A code that classifies the general type of substance. This is used for searching, sorting
and display purposes."/><commentvalue="The level of granularity is defined by the category concepts in the value set. More
fine-grained filtering can be performed using the metadata and/or terminology hierarchy
in Substance.code."/><minvalue="0"/><maxvalue="*"/><type><codevalue="CodeableConcept"/></type><isSummaryvalue="true"/><binding><extensionurl="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"><valueStringvalue="SubstanceCategory"/></extension><strengthvalue="extensible"/><descriptionvalue="Category or classification of substance."/><valueSetvalue="http://hl7.org/fhir/ValueSet/substance-category"/></binding><mapping><identityvalue="w5"/><mapvalue="FiveWs.class"/></mapping><mapping><identityvalue="rim"/><mapvalue=".code"/></mapping></element><elementid="Substance.code"><pathvalue="Substance.code"/><shortvalue="What substance this is"/><definitionvalue="A code (or set of codes) that identify this substance."/><commentvalue="This could be a reference to an externally defined code. It could also be a locally assigned
code (e.g. a formulary), optionally with translations to the standard drug codes."/><minvalue="1"/><maxvalue="1"/><type><codevalue="CodeableConcept"/></type><isSummaryvalue="true"/><binding><extensionurl="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"><valueStringvalue="SubstanceCode"/></extension><strengthvalue="example"/><descriptionvalue="Substance codes."/><valueSetvalue="http://hl7.org/fhir/ValueSet/substance-code"/></binding><mapping><identityvalue="w5"/><mapvalue="FiveWs.what[x]"/></mapping><mapping><identityvalue="rim"/><mapvalue=".code"/></mapping><mapping><identityvalue="orim"/><mapvalue="fhir:Substance.code rdfs:subPropertyOf rim:Entity.code"/></mapping></element><elementid="Substance.description"><pathvalue="Substance.description"/><shortvalue="Textual description of the substance, comments"/><definitionvalue="A description of the substance - its appearance, handling requirements, and other usage
notes."/><minvalue="0"/><maxvalue="1"/><type><codevalue="string"/></type><isSummaryvalue="true"/><mapping><identityvalue="rim"/><mapvalue=".player.desc"/></mapping></element><elementid="Substance.instance"><pathvalue="Substance.instance"/><shortvalue="If this describes a specific package/container of the substance"/><definitionvalue="Substance may be used to describe a kind of substance, or a specific package/container
of the substance: an instance."/><minvalue="0"/><maxvalue="*"/><type><codevalue="BackboneElement"/></type><meaningWhenMissingvalue="If this element is not present, then the substance resource describes a kind of substance"/><isSummaryvalue="true"/><mapping><identityvalue="rim"/><mapvalue=".player.determinerCode"/></mapping></element><elementid="Substance.instance.identifier"><pathvalue="Substance.instance.identifier"/><shortvalue="Identifier of the package/container"/><definitionvalue="Identifier associated with the package/container (usually a label affixed directly)."/><minvalue="0"/><maxvalue="1"/><type><codevalue="Identifier"/></type><isSummaryvalue="true"/><mapping><identityvalue="rim"/><mapvalue=".id"/></mapping></element><elementid="Substance.instance.expiry"><pathvalue="Substance.instance.expiry"/><shortvalue="When no longer valid to use"/><definitionvalue="When the substance is no longer valid to use. For some substances, a single arbitrary
date is used for expiry."/><minvalue="0"/><maxvalue="1"/><type><codevalue="dateTime"/></type><isSummaryvalue="true"/><mapping><identityvalue="rim"/><mapvalue=".expiryTime"/></mapping></element><elementid="Substance.instance.quantity"><pathvalue="Substance.instance.quantity"/><shortvalue="Amount of substance in the package"/><definitionvalue="The amount of the substance."/><minvalue="0"/><maxvalue="1"/><type><codevalue="Quantity"/><profilevalue="http://hl7.org/fhir/StructureDefinition/SimpleQuantity"/></type><isSummaryvalue="true"/><mapping><identityvalue="rim"/><mapvalue=".player.quantity"/></mapping></element><elementid="Substance.ingredient"><pathvalue="Substance.ingredient"/><shortvalue="Composition information about the substance"/><definitionvalue="A substance can be composed of other substances."/><minvalue="0"/><maxvalue="*"/><type><codevalue="BackboneElement"/></type><isSummaryvalue="true"/><mapping><identityvalue="rim"/><mapvalue=".player.scopesRole[classCode=INGR]"/></mapping></element><elementid="Substance.ingredient.quantity"><pathvalue="Substance.ingredient.quantity"/><shortvalue="Optional amount (concentration)"/><definitionvalue="The amount of the ingredient in the substance - a concentration ratio."/><minvalue="0"/><maxvalue="1"/><type><codevalue="Ratio"/></type><isSummaryvalue="true"/><mapping><identityvalue="rim"/><mapvalue=".quantity"/></mapping></element><elementid="Substance.ingredient.substance[x]"><pathvalue="Substance.ingredient.substance[x]"/><shortvalue="A component of the substance"/><definitionvalue="Another substance that is a component of this substance."/><minvalue="1"/><maxvalue="1"/><type><codevalue="CodeableConcept"/></type><type><codevalue="Reference"/><targetProfilevalue="http://hl7.org/fhir/StructureDefinition/Substance"/></type><isSummaryvalue="true"/><binding><extensionurl="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"><valueStringvalue="SubstanceIngredient"/></extension><strengthvalue="example"/><descriptionvalue="Substance Ingredient codes."/><valueSetvalue="http://hl7.org/fhir/ValueSet/substance-code"/></binding><mapping><identityvalue="rim"/><mapvalue=".player"/></mapping></element></differential></StructureDefinition>

Usage note: every effort has been made to ensure that the
examples are correct and useful, but they are not a normative part
of the specification.