I have a three monitor set up on Windows 7 and I sometimes lose track of where my cursor is. Is there any Windows shortcut to reset the mouse position? I'm guessing there is not, but might there be a way to set up a simple macro I could bind to a key combination to set my cursor to a default location, such as the center of the primary display?

I could write you a program that does this when you click - but you would have to find the mouse cursor and move it to the program icon to click. :-(
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Dave BeckerJan 30 '12 at 21:53

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@DaveBecker, how about a program that does it on execute? Then you can launch it with a shortcut-key.
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Hand-E-FoodJan 30 '12 at 22:05

I personally think everyone should turn on the position cursor to the default button. Everyone always looks for the program window first, then thinks about moving the cursor to such. Also I believe everyone should change their cursor scheme to the Extra Large Black cursor, since there is a plague of white/light colored backgrounds.
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surfasbJan 31 '12 at 6:00

PowerShell scripts require the execution policy to be changed, if you haven't done so already. You would need to change it permanently or run PowerShell.exe with the "-ExecutionPolicy RemoteSigned" argument.
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Patrick S.Jan 31 '12 at 0:28

@Hand-E-Food You must have changed the execution policy on your machine or something because I was unable to get your answer to work as written. I had to change the target to %systemroot%\system32\windowspowershell\v1.0\powershell.exe -ExecutionPolicy RemoteSigned "C:\PathToScript\CentreCursor.ps1" to get it to work. I re-ordered the arguments, Patrick's command had to come before the file. I've updated your answer to reflect this.
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tehDorfFeb 10 '12 at 22:51

Turning on "Show location of pointer when I press the CTRL key" is one option. This is especially useful if it is currently changed to some custom mouse pointer by an application, like a paint brush, that is harder to see.

PowerShell scripts require the execution policy to be changed, if you haven't done so already. You would need to change it permanently or run PowerShell.exe with the "-ExecutionPolicy RemoteSigned" argument.
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Patrick S.Jan 31 '12 at 0:28

but on the issue of finding your mouse you CAN turn on "pointer sonar" so your pointer will be honed into when you press the control key. (currently on a mac but I will try and get screen shots in a moment and edit it in)

regarding macro idea. I guess its plausible...but I dont know of any app that has this already programed, or how to program this myself