Tag: "modulates" at biology news

...rotein called Ldlr. They found that AR expression modulates atherosclerosis development in the diabetic animals. Thus, inhibitors of AR or other proteins that mediate glucose toxicity may be useful for treating diabetic atherosclerosis. TITLE: Human aldose reductase expression accelerates diabetic atheroscl...

...rly in the specification of stem cell progeny that modulates their ability to differentiate into the proper cell type," Snchez Alvarado said. How this molecule is modulating stem cells is one of the next steps that he and Reddien are trying to solve. The answer could have far-reaching implications, beca...

...ellular functions besides aging, and an agent that modulates sirtuins, such as DHC, could not only affect aging but also other critical functions, such as metabolism, neurodegeneration and cancer." Sirtuin enzymes are histone deacetylases, which modify the structure of chromatins, complex substances made up of...

... visual processing during which sexual orientation modulates how we perceive individual faces. The findings are reported by Felicitas Kranz and Alumit Ishai of the University of Zurich. Of all the visual skills possessed by humans, face recognition is arguably the most developed. Past brain imaging studies ha...

... to the parts of the cell they need to go. It also modulates calcium levels, which is critical for proper vision. When calnexin goes awry, however, calcium levels build up and the proteins that depend on it malfunction, says senior author Nansi Jo Colley, a medical geneticist at the UW-Madison departments of...

..."burst firing" is how the brain signals reward and modulates goal-directed behavior. But just how the stimulus you perceive causes neurons to switch into or out of this mode has been a mystery. Using anesthetized rats, Lodge and Grace found that one area in the brain stem, known as the laterodorsal tegmental ...

... parasites mount an anti-inflammatory defense that modulates it," said Mansfield, a professor of large animal clinical sciences. "The greater the immune response, the greater the anti-inflammatory effect. "It's possible that the human immune system developed in a way that is dependent on parasitic worms to reg...

...o the clock and the cell cycle. The clock normally modulates expression of this gene that encodes an important cell cycle regulator, and that cell cycle regulator in turn affects not only the cell cycle but also the clock. Recent evidence in mammalian cells shows that other cell cycle regulators physically ...

...ake the right connections. We've found that copper modulates very critical events within the central nervous system that influence how well we think." The research was led by neuroscience graduate students Michelle Schlief, Ph.D., and Tim West, Ph.D., in collaboration with Anne Marie Craig, Ph.D., and David M...

...he researchers further demonstrated that rapamycin modulates a signaling molecule linked to cell death and suggested that combination therapy with rapamycin and GC may be useful for treatment of ALL. Results from these two studies demonstrate that the gene expression-based chemical genomic approach represent...

...ing speed: In the case of the guinea fowl, the leg modulates itself within 26 milliseconds as it falls into an unexpected void. The lower limbs' spring action helps the birds retain energy and momentum, stabilize their center of mass, and continue forward motion through the hole. Biewener says this work coul...

...0268 and another potential drug, Afzoxifene, which modulates the estrogen receptor, synergize in the prevention and treatment of certain mammary tumors in mice," said Liby. "This study takes our work further, establishing a relationship between CDDO-ME triterpenoids, which are also effective anti-inflammation ...

...ope to learn more about how and how much the clock modulates their sense of smell, and which cells and genes are needed. The olfactory bulb biological clock study opens up many questions, a key one of which is: Why are there multiple clocks? "This idea of multiple biological clocks is new," Herzog said. "We...

... This experiment showed that cognitive information modulates the coding of motor information via neurons which belong to the two key structures in the basal ganglia: at entry and exit. This is the first time that a cellular interaction has been demonstrated between purely cognitive and purely motor informatio...

...on the skin and lungs); the ways in which nicotine modulates adolescent brain plasticity, interacts with other drugs during sensitive developmental periods, and, when used along with alcohol by a woman during pregnancy, alters drug responsiveness in offspring; an examination of why children, adolescents and a...