During the time Lopez had been arrested for dealing drugs, nightclub entrepreneur Anthony Prince had begun hiring doormen for his two new nightclubs: the Maisonette 9 and gay club Hercules. Eventually, Prince found Luis in a youth program. Lopez accepted the job, eventually becoming Prince's bodyguard. He cut all remaining ties he held with Gomez and Valerio, with the exception of Torres and Bardas. Unfortunately, Prince was in debt to several criminals across the city, Mori Kibbutz, a fitness enthusiast and Rocco Pelosi, a member of the Ancelotti crime family, to name a few. Lopez also worked casually with the multibillionare real estate developer Yusuf Amir and Russian gangster Ray Bulgarin, who would later attempt to murder Luis and Prince.

Lopez's third appearance was alongside Prince in the mission "Diamonds Are a Girl's Best Friend", in which he watches over the exchange between the diamonds, which Luis had originally stole, and Gracie Ancelotti. The exchange was interrupted by Ray Bulgarin, who believed Prince and Lopez had stolen the diamonds from him, and sent his men to murder all parties who were attending the exchange.

The Lost And Damned

Luis appears in The Lost and Damned twice; once during the game's rendition of the mission "Museum Piece", and then once again in the mission "Diamonds in the Rough", where Johnny Klebitz attemps to steal the conflict diamonds being sold to Prince. When the deal is ambushed, Luis orders Prince's boyfriend, Evan Moss, to escape with the diamonds in Moss' limo, while Luis escorts Prince to safety. It is revealed in The Ballad of Gay Tony that during Lopez and Prince's escape, members of the Lost Motorcycle Club tailed them, attemping to murder the pair. Klebitz eventually stole the diamonds from Moss, before murdering him.

Mission appearances

Trivia

It is revealed that Luis did a stint in prison as a result of a crime committed with Armando Torres and Henrique Bardas (neither of whom were caught).

Lopez went to juvenile hall for shooting a teacher who felt up his sister.

If Niko responds negatively to the e-mail "Brucie Owns Reality. Bro!", Niko writes: "There are more important things in life than being a celebrity or having good abs. You've been spending too much time fluffing the bouncer at the Maisonette 9", which could be referring to Luis, but also Dessie as well.

Gracie occasionally teases Luis and suggests that he is a closeted homosexual.

In the mission "Blog This!...", Luis tells Prince and Gracie Ancelotti that he had a short-lived relationship with Dani Lupisella, a mobster's daughter who threatened to have her father "chop his balls off" if or when the relationship ended.

Out of all the GTA IV protagonists, Luis is the youngest at 25 years old with Niko Bellic being 30 and Johnny Klebitz being 34.

Luis is legally able to pilot a helicopter, as shown from his Higgins Helitours piloting certificate in his apartment.

Luis admits to Gay Tony that he has anger issues, during Chinese Takeout after he knocked down the Triad he discusses with Tony that pointing a gun at him angers him, Tony himself also has anger issues.

From GTA IV to The Lost and Damned, Luis' appearance has changed from a stocky individual to a muscluar guy. In The Ballad of Gay Tony his legs are a bit thinner.