SIDE EFFECTS

Dermatologic: local swelling, occasionally with pain and pruritis, at the injection site may occur following subcutaneous administration; local and generalized skinrash have been noted after chronic subcutaneous administration.

DRUG INTERACTIONS

The Factrel (gonadorelin) test should be conducted in the absence of other drugs which directly affect the pituitary secretion of the gonadotropins. These would include a variety of preparations which contain androgens, estrogens, progestins, or glucocorticoids. The gonadotropin levels may be transiently elevated by spironolactone, minimally elevated by levodopa, and suppressed by oral contraceptives and digoxin. The response to Factrel (gonadorelin) may be blunted by phenothiazines and dopamine antagonists which cause a rise in prolactin.

Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.