over the trial that felt her guilty talked about what he called his suffering over the decision. Will Amanda Knox be sent back to Italy? Here's ABC's Elizabeth vargas. Reporter: Amanda Knox clearly shaken by the news, an Italian court convicted her for a second time of murder. Yesterday, she told robin Roberts how she got the news. I was with my family and was able to find an Italian TV station online. My first reaction, no, this is wrong and I'm going to do everything I can to prove that it is. Reporter: Nearly 28 months after being acquitted of killing british roommate, Meredith Kercher, another reversal of fortune. She was sentenced to 28 1/2 years in prison. Her Italian boyfriend was given 25 years. This really has hit me like a train. I did not expect this to happen. I really expected so much better from the Italian justice system. They found me innocent before. How can they say it's guilt beyond a reasonable doubt? Reporter: Knox vowed to keep fighting. The judge in the case said he quote suffered over the verdict but added the court agreed there was a motive that would be made public in the future. Knox's lawyers will wait for the court's reasoning and then make another appeal. But could she be ultimately extradited to Italy? Are you prepared for that? I'm not. I will never go willingly back to the place where I -- I'm going to fight this until the very end. And my "20/20" co-anchor Elizabeth vargas is here with us tonight. Elizabeth, you traveled to Italy for six years now, back and forth. Was there ever new piece of evidence, a bombshell smoking gun here? No, there wasn't. There's three trials, no evidence introduced. It's baffling how the verdict has gone from guilty to innocent. Not not guilty, but innocent, now back to guilty again. The big question is, will Amanda Knox be sent back to Italy? This has to work through the Italian justice system. That will take several years. It will come back to this country if they ask for her to be returned to Italy. And it will work its way through the court system here. But if the judge in the united States says, she has to go back. She does. She has to go back unless, of course, she's on the run. All right, Elizabeth vargas, thank you. She'll have a special edition of "20/20," Amanda Knox guilty again. That's 10:00 P.M. Tonight. With the olympics in sochi

This transcript has been automatically generated and may not be 100% accurate.

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