Background*

Dr. Jeffrey D. Rothstein, Jeff, M.D., Ph.D served as Scientific Founder of Psyadon Pharmaceuticals, Inc. (Formerly Ruxton Pharmaceuticals, Inc.). Dr. Rothstein is Professor of Neurology and Neuroscience, and Vice Chairman for Research in the Department of Neurology, Johns Hopkins University. Dr. Rothstein is an internationally recognized expert on neurodegenerative disease, with a specialty in Amyotrophic Lateral Sclerosis (ALS). He is a recognized leader in the field ... of glutamate excitotoxicity and glutamate transporter biology. He serves as a Director of Psyadon Pharmaceuticals, Inc. He serves as a Member of Scientific Advisory Board at Cytokinetics, Incorporated. He serves as the Principal Investigator in a dozen national and international clinical trials. His research on transporter systems has established a clear role for these proteins in various aspects of neurological diseases. He directs over $10 million in grants from the NIH, the Muscular Dystrophy Association, and private philanthropy, employing 25 post docs, junior faculty and graduate students to investigate the pathogenesis of ALS, novel therapies, and the basic synaptic biology of glutamate transporters. Dr. Rothstein directs the Packard Center for ALS Research, the first multi-investigator, multi-institutional, international collaborative research Center for aggressively targeting ALS pathogenesis and novel therapeutics for ALS. He directly oversees the distribution of ALS Center research and $2 million in annual grants distributed by the Center. He has successfully carried out "bench-to-bedside" research with ALS relevant drugs identified in his lab and carried forward into clinical trials,a member of the Program for Cellular and Molecular Medicine, Director of the Packard Center for ALS Research. He has published more than 120 peer-reviewed articles. Dr. Rothstein graduated from Colgate University (BA), the University of Chicago (MA), and the University of Illinois (MD, PhD). He completed his internship at the University of North Carolina Chapel Hill, followed by a neurology residency at Johns Hopkins where he has remained since 1986.

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