ATP adds a phosphate to the protein to power the conformational change.

As the transport protein changes conformation, it moves bound particles across the membrane.

Na+ K+ pump move 3 Na+ molecules out of the cell for every 2 K+ ions pumped into the cell.

IX. Some ion pumps generate voltage across membranes
Because positively and negatively charged ions are unequally distributed across the plasma membrane, all cells have voltages across their plasma membranes.

This difference in charge across a membrane allows multiple cellular process such as action potentials along nerve cells, and chemiosmosis which is used to produce ATP.

Particles are moved across a membrane to set up a charge difference by an electrogenic pump = a transport protein the generates voltage across a membrane.

Na+/K+ ATPase is the major electrogenic pump in animal cells.

a Proton pump is the major electrogenic pump in plants, bacteria, and fungi. Also, mitochondria and chloroplast use a proton pump to drive ATP synthesis.

Voltage created by electrogenic pumps are sources of potential energy available to do cellular work.