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VRI, one of the nation's largest in-home medical health monitoring solutions companies, recently In 2011, Dayton was ranked the #3 city in the United States for excellence in health care.The ranking is from Health Grade's list of America’s Top 50 Cities for Hospital Care.In 2013, Ohio was ranked in the top ten states for best business climate by Site Selection magazine, based on a business-activity database. exports in 2009, with top destinations being Canada at .2 billion, followed by Mexico, China, United Kingdom, Greece, Brazil, Japan, Germany, France, and Australia.The state was edged out by Texas and Nebraska for the 2013 Governor's Cup award from the magazine, based on business growth and economic development. As of 2010, Ohio was #6 in the country for Fortune 500 companies with 23.A new report by the Quantitative Economics and Statistics Practices (QUEST) of Ernst & Young in conjunction with the Council On State Taxation (COST), ranks Ohio as third in the nation for friendliest tax environment.The study, "Competitiveness of state and local business taxes on new investment," provides a state-by-state comparison of tax liabilities.They include Cardinal Health at #17, Procter & Gamble at #22, Kroger at #23, Macy's at #103, Nationwide Insurance at #118, Goodyear Tire and Rubber at #141, Progressive Insurance at #161, American Electric Power at #172, Eaton Corporation at #194, and Owens Corning at #432.Dayton is designated as the state's aerospace hub due to its high concentration of aerospace and aviation technology.

The state is recognized internationally as the "Fuel Cell Corridor", A new report by the Quantitative Economics and Statistics Practices (QUEST) of Ernst & Young in conjunction with the Council On State Taxation (COST), ranks Ohio as third in the nation for friendliest tax environment.

RTI International Metals's location in Niles produces titanium used in every France-based Airbus aircraft.

RTI was originally headquartered in Niles before moving to Pittsburgh in the 21st century, while Airbus has invested .3 billion in the state.

In 2010, EPISCENTER, a new R&D center for the corporation to be located in Dayton, was announced by the Third Frontier program.

Boeing's Central Ohio Aerospace and Technology Center in Heath is a venture amongst five of the top 10 U. defense contractors, including Atlantic Inertial Systems, Honeywell, Kearfott, Northrop-Grumman, L3 Communications, and Raytheon, which is also the headquarters of the Air Force Metrology and Calibration Program Office.