Disease: Meningococcus

This report, published in Human Vaccines, describes developments in meningococcal disease vaccines presented at the 16th International Pathogenic Neisseria Conference in Rotterdam in September 2008. It includes progress on an …

This poster, presented at the 2008 International Pathogenic Neisseria Conference, displays a detailed analysis of long-term surveillance data from Burkina Faso, Mali, and Niger during the past 20 years in order to understand the dynamics of …

This online library gathers resources specifically related to adult immunization, providing healthcare providers and the general public with access to relevant resources that can be used in a clinic setting or for individual education. It includes …

This supplement of Vaccine contains 16 articles that cover a broad spectrum of important issues in vaccine science, including vaccine safety, efficacy, and implementation. The overarching theme revolves around identifying barriers to vaccination and …

Though generally very rare or minor, there are side effects, or “adverse effects,” associated with some vaccines. This report provides an analysis of more than 1,000 research articles that were reviewed to assess the risk of specific adverse …

MenAfriVac™ is a new meningococcal A conjugate vaccine developed to prevent meningitis outbreaks in Africa. It was first introduced during the last quarter of 2010 in three West African countries. The authors of this article, published in …

The vaccine MenAfriVac™ has the potential to confer herd immunity by reducing carriage prevalence of epidemic strains. To better understand this phenomenon, the authors of this article, published in Clinical and Vaccine …

Pneumococcus, meningococcus and Haemophilus influenzae cause a similar spectrum of infections in the ear, lung, blood, and brain. They share cross-reactive antigens that bind to the laminin receptor of the blood-brain barrier as a molecular basis …

This article, published in Nature Medicine, reviews current successful vaccines and identifies their mechanisms of protection in the hopes of tackling the challenges posed by those infectious targets that have thus far escaped successful …

This article, published in Vaccine, discusses the challenges of achieving control of meningococcal disease in low- and middle-income countries. The authors argue that in low-income countries the main challenge is a lack of sufficient epidemiological …

The authors of this article, published in Vaccine, discuss how the introduction of vaccines against Neisseria meningitidis raises the question of whether disease caused by this obligate human bacterium can be controlled, eliminated, or even …

This poster, presented at the 16th International Pathogenic Neisseria Conference in the Netherlands, discusses a study that aimed to provide preliminary information regarding meningococcal carriage in West Africa and on the effect on …

This website provides information about the work of PATH’s Center for Vaccine Innovation and Access, which brings together expertise across every stage of vaccine research, development, and introduction to make lifesaving vaccines globally …

This article, published in Clinical Infectious Diseases, describes the epidemiologic landscape of meningococcal disease in the United States from 1998 to 2007, including an analysis of the disease before and during the implementation of adolescent …

The epidemiology of Invasive Meningococcal Disease (IMD) is distinct in the United States and Canada compared with other countries. This review, published in Human Vaccines & Immunotherapeutics, describes the incidence, mortality, and …

This study, published in PLoS Medicine, provides a clear, quantitative demonstration of the connections that exist between major meningococcal meningitis (MCM) epidemics and regional climate variability in Africa. This statistically robust …

This article, published in the Journal of Preventative Medicine and Hygiene, provides an overview of the disease burden of meningococcal disease and the various vaccines available for meningococcal disease serogroups. Although relatively rare, …

This article, published in Transactions of the Royal Society of Tropical Medicine and Hygiene, reviews the classification of epidemic strains of Neisseria meningitidis and the expression by meningococci of both constant and highly variable …

This study, published in PLoS Medicine, aimed to determine how levels of colonization with different bacterial meingococcal serogroups change over time, and how the patterns of disease relate to such changes in the Kassena-Nankana District of …

This article, published in Médecine et Maladies Infectieuses, provides an overview of a cross-sectional, descriptive study to identify strains of Neisseria meningitidis isolated from 2005 to 2007 in Mali. Neisseria meningitidis appeared in 144 …

The Meningitis Vaccine Project (MVP) was established with the goal of developing, testing, licensing, and introducing an affordable group A meningococcal conjugate vaccine for Africa. The authors of this article, published in Vaccine, describe the …

This article, published in Tropical Medicine & International Health, asserts that surveillance systems and techniques for diagnosing bacterial meningitis and pneumococcal disease in the African meningitis belt have improved greatly over the …

This review, published in Expert Review of Vaccines, looks at what has been learned from developing conjugate vaccines against Haemophilus influenzae type b, Streptococcus pneumoniae, and group C Neisseria meningitidis that could be useful for the …

These guidelines, designed for physicians, laboratory workers, and health care administrators, provide comprehensive information on epidemiology and standard techniques for diagnosis, treatment, prevention, and control of meningococcal disease …

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