It is characterised by hyperglycaemia, hyperketonaemia and metabolic acidosis, and has been somewhat arbitrarily divided into mild, moderate and severe based upon biochemical and clinical features (Table 12.1 Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP Diabetic ketoacidosis (DKA) is a state of severe uncontrolled diabetes caused by insulin deficiency.

Finally, they took their daughter to her primary MD, avoiding the Diabetes Disasters of dehydration, acidosis, and the potential need of hospitalization&hellip Sometimes being a medical professional can have a major impact on the people around us outside of work. Recently, my neighbor''s 12 year old daughter had a drastic change in her health. I noticed that she had lost a lot of weight, started drinking juice by the gallons, had no energy, and lost the twinkle in her eyes.

Three years later, patient weighed 275 lbs due to unknown reason and he was diagnosed with type I diabetes based on a random blood glucose of 684mg/dl accompanied by ketonemia and a metabolic acidosis. An African-American male was diagnosed with heart failure at age 38 due to severe hypertension. At age 40, patient weighed 166lbs and he had normal glucose tolerance test. MORE >>

Researchers have developed an implantable molecular device that monitors acid build-up in the body for people with diabetes and produces insulin if acidosis becomes a risk. A team of bioengineers from ETH Zurich s Department of Biosystems Science and Engineering (D-BSSE) in Basel developed the device which is composed of two modules: a sensor that constantly measures blood pH and a gene feedback mechanism that produces the necessary amount of insulin. MORE >>

Despite its strong safety profile, the FDA has long recommended that metformin not be prescribed to patients with mild to moderate kidney disease due to the risk of lactic acidosis, a potentially serious condition. The most popular treatment for type 2 diabetes, metformin, may be safer for patients with mild to moderate kidney disease than guidelines suggest, according to a new, systematic review of the literature. For 20 years, metformin has been used in the U.S. MORE >>

– 9% and increases along with age, level of consciousness on admission, degree of hyperosmolality and acidosis, as well as severity of azotemia.5,6 In the US, hospitalizations due to DKA reach 100,000 and the cost of treatment has been reported as 1 billion dollars per year.7.Diabetic ketoacidosis (DKA) is an acute complication of diabetes mellitus. It is characterized by the triad of hyperglycemia, ketosis, and metabolic acidosis.1 MORE >>

NEW DELHI: Three new type-2 diabetes medicines, two of which were recently launched in India, have come under the scanner of the US drug regulator for potential risk of causing acidosis that could require hospitalization All the three drugs have been available in developed countries like the US and Europe since around 2012-13. MORE >>