Clinical Trials

The purpose of this study is to determine whether shotgun sequencing technology, which can
be used to detect donor DNA in recipient plasma, can be used as a rapid, accurate,
non-invasive method to detect Acute Cellular Rejection (ACR) after heart transplantation.
Currently, all heart transplant recipients undergo invasive heart biopsies to diagnose ACR.
Thus, there is an ongoing need to monitor patients for the development of acute and chronic
rejection, with the primary goal of non-invasive early detection and treatment to prevent
organ damage.