RT Journal
A1 Ho P, Zeng C, Tavel HM, et al
T1 TRends in first-line therapy for hypertension in the cardiovascular research network hypertension registry, 2002-2007
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 2010
FD May 24
VO 170
IS 10
SP 912
OP 913
DO 10.1001/archinternmed.2010.102
UL http://dx.doi.org/10.1001/archinternmed.2010.102
AB
Since publication of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) (December 2002) and Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC-7) (May 2003) guidelines, thiazide diuretics have been promoted as the preferred initial agents for hypertension treatment, especially among patients without compelling indications for an alternative medication class.1,2 A few prior studies demonstrated a slight increase in thiazide use shortly following the publication of these data, but the extent to which thiazides continue to be used as a first-line agent in hypertension treatment in current practice is unclear.3,4