The series stars Alley as Madison Banks, a Broadway star whose life is turned upside-down when the son she gave up at birth returns onto the scene. Perlman plays Thelma, Banks' assistant and best friend.

Oddly, "Kirstie" will also serve as host to a "Seinfeld" reunion; earlier this week Jason Alexander signed on to play Banks' Broadway agent, joining a cast that already includes Michael Richards as Banks' eccentric driver.