Abnormal epidermal turnover in psoriatic skin impairs its barrier function and tissue repair capabilities. Therefore, studies of hyperkeratinization and hyperproliferation have been conducted to better understand the disease. Here, the administration of heavy water and a tape-stripping method are used to measure skin protein turnover in psoriatic skin and surrounding tissues. Results demonstrate benefits over other proliferation measurements.

From the December 2001 issue of Cosmetics & Toiletries, this article describes how both bending and abrasion should be tested–along with extension–when evaluating hair strength, as the authors show here in tests of an active developed to increase the strength of bleached hair.

Nov 20, 2013

The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) has requested the submission of new science or information on alternative test methods or testing strategies for skin sensitization, as part of a plan of action to advance this area.