Human Amyloid-Beta Detection

The accumulation of amyloid-beta protein plaques in the cerebral cortex is a hallmark of Alzheimer's disease (AD). Amyloid-beta is produced by the proteolytic cleavage of amyloid precursor protein (APP), which is mediated by the enzymes beta- and gamma-secretase. This cleavage reaction produces a number of peptides ranging from 36 to 43 amino acids in length. Our antibodies and ELISA kits detect a variety of human amyloid-beta variants and oligomers.

ELISAs for Human Amyloid-Beta Detection

Amyloid-beta insoluble protein is the main component of plaques found in the brains of patients with AD; however, recent research suggests that soluble, oligomeric forms of Amyloid-Beta are also involved in this disease. The amyloid-beta kits are solid-phase sandwich ELISAs that use two highly specific antibodies—one is precoated onto the ELISA plate and the other is HRP-conjugated.

Additional Information

Please see a product's User Manual and Data Sheet for information about storage conditions, product components, and technical specifications. Please see the User Manual to determine kit components. User Manuals and Data Sheets are located under the Documents tab.