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Venerdì 18 aprile 2008 Torino Frailty is a recently identified condition resulting from a severely impaired homeostatic reserve, that places the elderly at the highest risk for adverse health outcomes, including dependency, institutionalization and death, following even trivial events. Senin U, Cherubini A, Mecocci P. [Impact of population aging on the social and the health care system: need for a new model of long-term care] Ann Ital Med Int Jan-Mar;18(1):6-15. Frailty : definition