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In over 20 years, Wonderup S.a.g.l. with natural products to its Naturdie-ta line, has grown steadily up the challenges of the market and offering himself as a landmark in the field of natural cosmetics and supplements, with safe and effective formulas from a long experience and continuous research [read more ...]

Essential characteristics

Medicamentous use

Affections of the ligaments and joint disorders , periarthritis, tendinitis and fibromyalgia, backache, degenerative diseases of the osteoarticular apparatus, dyspepsia and depressed appetite.

Pharmacological properties

The common name of the medicament popular is “Devil’s Claw”, transposed to the letter in the English-speaking world in “Devil’s Claw” and conferred for singular extensions to “hook” of his woody fruit that is not used for therapeutic purposes. In traditional medicine it was used for its pain-relieving effects and antipyretic properties.

Preliminary studies have found that the quality of Harpagophytum called cortisone vegetable are mainly analgesic and anti-inflammatory response with particular orientation to the locomotor apparatus. Were also identified clear outcomes on digestion thanks to the bitter essences existing in the plant. Many have been until now the hypotheses drawn on the mechanism of action for anti-inflammatory outcomes that still remain obscure.

The Harpagophytum was equated to corticosteroids, without showing contraindications but it is controversial supposition of an involvement of the arachidonic acid cascade. The validity has been admitted by recent pharmacological and clinical research for the most part verified with placebo and times to say that the assumption of Harpagophytum attenuate the inflammatory persistent pain in the developments in the joints.

As often happens in herbal medicine, the pharmacological research activity dell'Arpagofito have provided evidence that the “phytocomplex” is equipped with a total activity more valid and detailed statement of the individual active substances such iridosidi harpagoside and arpagide (amaroidi).

Devil’s Claw or Harpagophytum Procumbens, can be referred to as “cure” of the joints since found indications in the treatment of rheumatism, arthritis and other painful articular manifestations.

The anti-inflammatory and analgesic qualities have been confirmed by scientific research qualified. Studies carried out in arthritic subjects have shown that the use of devil’s claw reduces significantly pain, making it much better chance of moving and articulate agility.

Devil’s claw is now unanimously known, so that can be an effective substitute of the classical anti-inflammatory therapies. The tree also gives excellent results in treatment of disorders of athletes such as tendonitis. Another significant characteristic possessed by the devil’s claw is to facilitate the removal of uric acid, resulting effective in the treatment of gout.

Pharmacological constituents

The main component is harpagoside, followed by procumbide and from procumboside. These are of iridoid glycosides that are hydrolyzed in the gastrointestinal tract by acid hydrolysis and / or enzymatic. It is a drug rich in sugars, both simple that complex and includes triterpenes, esters eterosidics phenyl propanics, phenolic acids, free and esterified phytosterols, flavonoids, fats and waxes.

Main indications

Rheumatic disorders and small sports traumatology.

Main action

Anti-inflammatory and analgesic.

contraindications

It is not recommended in children under 12 years of age, pregnant and lactating women.

Pharmacodynamic Interactions

The harmfulness of Harpagophytum is considered to be very low, but are not recommended for use in case of ulcers, arrhythmias, and it is hypothesized a possible interaction with anticoagulant medicines.