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Research among serodiscordant couples (where one partner is living with HIV and the other is not) shows that consistent condom use significantly reduces the risk of HIV transmission both from men to women and women to men Condoms have played a decisive role in HIV, STI and pregnancy prevention efforts in many countries.

Condoms have helped to reduce HIV transmission and curtailed the broader spread of HIV in settings where the epidemic is concentrated in specific populations.

Biomedical interventions including antiretroviral therapy (ART) for people living with HIV can substantially reduce HIV transmission.

While the success of ART may alter the perception of risk associated with HIV, studies have shown that people living with HIV who are enrolled in treatment programmes and have access to condoms report higher condom use compared to those not enrolled.

Oral pre-exposure prophylaxis (Pr EP)—where antiretroviral drugs are used by HIV-negative people to reduce their risk of acquiring HIV—is also effective in preventing HIV acquisition, but is not yet widely available and is currently only recommended as an additional tool for people at higher risk, such as people in sero-discordant relationships, men who have sex with men and female sex workers, in particular in circumstances in which consistent condom use is difficult to achieve.

Hence, condom use remains complementary to all other HIV prevention methods, including ART and Pr EP, in particular when other STIs and unintended pregnancy are of concern.

In 2013, an estimated 2.1 million people became newly infected with HIV These three public health priorities require a decisive response using all available tools, with condoms playing a central role.