2sxc has almost no ties to WebForms except for the Admin-UI in the background which we'll replace with an Angular UI within the next few months. So we're basically already vNext capable - so of all the DNN parts you'll need migrated, 2sxc will be there first
:).

Angular 2: We promote the use of angular in our blogs and trainings - but we're built in such a way that you can use any framework you want. This of course also includes angular2.