I have a MacBook Pro with Retina Screen running OS X 10.8.2, and just installed ST2 build 2220 because I was having some serious performance issues with scrolling and selecting text. While this build does seem to be smoother, it is now constantly eating about 15% of my CPU while the app is in focus and a window is open, which is JUST enough to start my fans up. Screenshot of Activity Monitor:

Same problem!!I backed to Build 2217 now,even though this build is super super super slow on a retina MBP! But I think this is far better than making the fan run constantly! which make the whole body of MBP very hot!

On the other hand Safari does a very good job on scrolling and selecting text , smoothly and very low CPU usage.May be they're using the GPU rather than a CPU?Anyway I think this issue can be solved perfectly on the next major update.