Even someone like Mayim Bialik, who appears on one of TV’s most popular sitcoms (“The Big Bang Theory”), can get a little star struck.

Especially when the star is the world’s coolest star expert.

Neil deGrasse TysonPhoto: Jonathan Baskin

“I can’t believe that he’s tweeting at me,” Bialik says of Neil deGrasse Tyson, the director of the Hayden Planetarium and host of the upcoming “Cosmos” series on Fox — whose appearances on TV, podcasts and comedy shows have made him the Justin Timberlake of the science world.

Bialik will share the stage with Tyson on Monday at the Brooklyn Academy of Music, along with comedian Eugene Mirmam (of “Bob’s Burgers”) and other surprise guests, for a live version of Mirman and Tyson’s podcast “StarTalk Radio.”

“Any time you have someone who is one of the greatest minds of our times in any field, it’s such a gigantic crossover of pop culture and culture,” she says.

Bialik rose to fame in the ’90s as the star of “Blossom” and is no stranger to science. She plays neurobiologist Amy Farrah Fowler on “The Big Bang Theory” and has a real-life Ph.D. in neuroscience from UCLA.

Her interest in the field grew out of a fascination with how neurons affect human experiences, such as love and consciousness. The degree occasionally comes in handy on the show, where she gives tips on what her character would be doing in the lab, or what kinds of equipment should be on hand.

“It seems more like a room of academics than comedy writers,” she says. “It’s like a nerd fest pretty much at any time if I’m involved in any conversation.”

Outside of acting, Bialik is involved in health and parenting advocacy and just published a cookbook this month, “Mayim’s Vegan Table: More than 100 Great-Tasting and Healthy Recipes from My Family to Yours.”

“My goal is not to make any one vegan. We all need to eat more fruits and vegetables and less processed foods,” she says. “It’s very approachable and human.”

“Approachable” is what shows like StarTalk have helped make science, especially in Brooklyn, the land of the nerd kings. Kids who are into those nerdy things have a good future in store, she says.

“Those things, I’m glad, are getting their moment in the sun,” she says.