Compared to other types of candies, Twizzlers do not have a strong flavor. They are also quite chewy.

Eating a Twizzler is like consuming a scented candle, but that hardly conveys the strange pleasure of the Twizzlers' smell and the satisfaction of masticating each strand into submission. A package of Twizzlers is more of a small hobby than a dining experience. Their durability and lack of surprise make them perfect for consumption during movies. They are a sort of gustatory pastime—the snack food equivalent of working on one's knitting.

At least two spinoff candies have been made using the Twizzlers brand name: Twizzlers Pull-n-Peel and Twizzlers Twist-n-Fill.

Twizzlers Pull-n-Peel was introduced in 1994. Flavors include "berry," cherry, grape, lemonade, orange, and strawberry-banana. The Pull-n-Peel features sticky candy strands two millimeters in diameter wrapped around one another into a rope. One peels these strands from the rope and consumes them individually. The Pull-n-Peel formula is too sweet and gummy to seriously consider gnawing into the rope wholesale without pulling it apart first, with a texture more like a Gummi bear than the traditional leathery, waxlike recipe.

The Twizzlers Twist-n-Fill candy was introduced in 2000. Twizzlers Twist-n-Fill have the Twizzlers' inner void filled with a fruity goo. Twist-n-Fill television commercials feature writhing, snakelike Twizzlers enthusiastically gorging themselves on various fruits.