Nece is a community activist involved in many charities throughout the Tampa Bay area. He is on the board of the Tampa Bay Sports Authority and Tampa's Lowry Park Zoo. In 2006 he created his own foundation "The Ryan Nece Foundation", funding programs for youth and families.

Nece tore his ACL in his rookie year, ending his season after being a stalwart special teams tackler throughout the season. In 2003, Nece moved into the starting spot across star linebacker Derrick Brooks and finished the season with 70 tackles and one interception.

Nece was released by the Buccaneers during final cuts on August 30, 2008 after which he then retired.

On August 31, 2008, Nece was signed by the Detroit Lions. The move reunited him with Lions head coach Rod Marinelli, who was an assistant coach for the Buccaneers during Nece's first four seasons in Tampa Bay. Nece was released by the Lions in the 2009 off-season.

With Marc Isenberg, Nece is the co-author of Go Pro Like a Pro, a small booklet from 2011 created for athletes, their parents, and others who influence, advise, and work on athletes’ behalf.[1]

The United Football league announced on September 14, 2010 that Nece would be doing sideline reporting during live games on the Versus network. He joined the Pac-12 Network as a sideline reporter and football analyst in 2012.