In this study we investigated the relationships between resilience, perceived social support, sensory processing, self-regulation and consuming attitudes and behaviors of alcohol, tobacco and other psychoactive substances. For this, we used six instruments, namely: Short version of the Social Support Questionnaire - SSQ6 (Sarason; Sarason, Shearin & Pierce, 1987); Adult / Adolescent Sensory Profile - SPA (Brown & Dunn, 2002); Short Self-regulation Questionnaire - SSRQ (Carey, Neal & Collins, 2004); Resilience Scale - ES (Wagnild & Young, 1993); Attitudes scales towards tobacco, alcohol and drugs - ESACTA-ESACAL-ESACDRO (García del Castillo, López-Sánchez, Segura & García del Castillo López, 2012). Scale consumption of tobacco, alcohol and other drugs - ESCON (García del Castillo, López-Sánchez, Gázquez & García del Castillo-López cit. por García del Castillo, 2011).The sample consisted of 340 healthy adult participants, of whom 261 (76.8%) were women and 79 (23.2%) men. As for chronological age, the youngest person was 18 and the oldest was 76 years (M = 39, SD = 11).Statistically significant connections between self-regulation and resilience were found. Self-regulation differed in an evident way with the consuming behaviours of tranquilizers. Resilience didn’t showed significant modifications with the consuming behaviours. But both variables showed connections with consuming attitudes.Social support correlated positively with self-regulation, but was solely in the aspect of satisfaction with social support that this trend was noted clearly.The number of support providers differed considerably with the use of tobacco and almost significantly with the consumption of alcohol, which suggests the afiliative scope of some psychoactive substances. Accordingly, the use of tobacco may be associated with a larger social network, but not with more quality of social support.Sensory processing was associated to the intake behaviors, particularly of tranquilizers and analgesics, insofar as the effects of these substances may be involved in the adults’ sensory modulation routines.Sensory imbalances appeared to be implicated in the decreased ability of cognitive-behavioral self-regulation, resilience and social support of individuals and therefore should not be neglected in future psychological research.