2 Answers
2

It means the program set to autorun isn't going to launch because it's not there.

Consider:

a program, one you aren't the
engineer of, put them there

they aren't hurting anything or slowing down your boot time

if it isn't broken, don't fix it until it is broken

Chances are slim you'd miss the program entries you removed, but if another bit of software installs another module later on, or an update puts the expected file in place, or a mode changes... well you'll have really weird problems nearly nobody else has seen (read: caused).