A coast-to-coast relay team will be striding along U.S. 70 Wednesday night as the One Run For Boston cross-country relay has hit the road for a second time in an effort to raise money for the victims of the Boston Marathon.

“We wanted to do something to help those impacted by the blasts,” said Danny Bent, one of the driving forces behind the run that will track 3,300 miles across 13 states.

Starting in California and ending in Boston, the cross-country runners headed down the Southwest trail on March 16, two days before the first anniversary of the bombing.

After crossing Arizona, the team is expected to reach Fort Sumner, N.M., by the end of Tuesday.

Wednesday, the cross-country team will hit U.S. 70 and will be scheduled to cross through Plainview at around 10 p.m. before heading to Lockney.

Last year, the event raised $91,000 for the victims of the Boston Marathon bombing.

“We had no idea if the relay would work, let alone take off in the extraordinary way that it did,” Bent said.

In 2014, the running group plans to “blaze an even brighter trail” as they have their goals set to raise $1 million for the victims. With donations being made on their website, www.onerunforboston.org, the runners have raised $265,957 as of 4 p.m. Tuesday afternoon.

The idea for the fundraising run came from three friends from England, Danny Bent, Kae Treleaven and Jamie Hay, who first organized the run in July 2013 in response to the bombing.

Over 2,000 runners took part in the One Run For Boston run last year, some travelling hundreds of miles from their home states to take part. They kept the baton moving around the clock through the deserts, lightning storms and torrential rain, according to a press release from the organization.

“One Run For Boston had a profound effect on many of the runners who took part,” Treleaven said. “So, when it was over, they didn’t simply walk away thinking ‘that’s it, job done.’ We soon realized that the relay had forged a new community of runners, powered by positivity and united by a desire to support the One Fund in its ongoing mission to help those impacted by the bombings.”

The route remains largely unchanged from last year, as they followed as southern course to avoid an increased risk of snow and ice. A number of new off road stages have also been added, including a 66-mile section of trail through the Caprock Canyon State Park.

Runners wanting to join the effort can sign up at the One Run For Boston website. Each runner is given their own online fundraising page which enables them to collect sponsorship for the One Fund Boston via the website.