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The second messenger cyclic AMP immobilized on agarose by an aminohexylamino spacer attached to position 2 of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. This ligand is also offered with a shorter spacer (2-AEA-cAMP-Agarose, Cat. No. A 110) and as PDE-resistant version (Sp-2-AHA-cAMPS-Agarose, Cat. No. A 069). Detailed technical information available. References: Scholten et al., J. Proteome Res., 5, 1435 - 1447 (2006); Margarucci et al., Mol. BioSyst., 7, 2311 - 2319 (2011); Hanke et al., N. Biotechnol., 28, 294 - 301 (2011). Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.