According to Greene, entrepreneurship is increasingly recognized as the necessary approach for identifying and solving economic and social problems around the world. "This approach only works if entrepreneurship is taught, learned and practiced as a mindset and specific skill set," she said. "In this talk, I will use the framework of the Goldman Sachs 10,000 Small Businesses Initiative in the United States and United Kingdom and the 10,000 Women Program, which has reached women in 42 developing countries, to talk about what it means to be entrepreneurial and how entrepreneurial behaviors reach from the development of individual businesses to addressing health and prevention challenges, and even changing economic and social structures."

Greene's research focuses on the identification, acquisition and combination of entrepreneurial resources, particularly by women and minority entrepreneurs. She is a founding member of the Diana Project, a research group focusing on women and the venture-capital industry. In addition, she is the author or co-author of several books, including Clearing the Hurdles: Women Building High Growth Businesses and The Development of University-Based Entrepreneurship Ecosystems: Global Practices. As well, her work has been published in numerous journals, including Venture Capital, Entrepreneurship Theory and Practice, Small Business Economics and The National Journal of Sociology. She serves on the editorial board of Academic of Management: Learning and Education.

Greene is a federally appointed member of the national advisory board for the Small Business Administration's Small Business Development Center Program. In addition, she is a fellow of the IC2 Institute at the University of Texas at Austin. Her past service work includes serving as co-chair of the steering committee for the Entrepreneurship Affinity Group of the Association to Advance Collegiate Schools of Business and sitting on the boards of the State of Missouri Small Business Development Centers, the Kansas Women's Business Center and the Helzberg Entrepreneurial Mentoring Program.

Greene served as provost, and before that, as dean of the Undergraduate School at Babson College before being named the Paul T. Babson Chair in Entrepreneurship at Babson College. Prior to joining Babson College, she held the Ewing Marion Kauffman/Missouri Chair in Entrepreneurial Leadership at the University of Missouri from 1998 to 2003 and the New Jersey Chair of Small Business and Entrepreneurship at Rutgers University from 1996 to 1998. She earned a bachelor's degree at Penn State; a master's degree at the University of Nevada, Las Vegas; and a doctoral degree at the University of Texas at Austin.