Vemox 500

Description

Pharmachologic effect:

Amoxicillin is an antibacterial bactericidal acid-resistant broad spectrum agent from the group of semisynthetic penicillins. Due to the broad spectrum of action, the drug is active against both gram-positive and gram-negative microorganisms. Clinically significant gram-negative microorganisms sensitive to amoxicillin include Escherichia coli, Proteus mirabilis, Salmonella, Shigella, Campilobacter, Haemophilus influenzae, Bordetella pertussis, Leptospira, Chlamydia.

Dosing and Administration:

Amoxicillin is administered orally, before or after a meal. Adults and children over 10 years of age (with a body weight of more than 40 kg) are prescribed 0.5 g 3 times a day; With a severe course of infection – 0.75-1 g 3 times a day.

In acute uncomplicated gonorrhea appoint 3 g once; In the treatment of women, repeated intake of this dose is recommended.

In acute infectious diseases of the gastrointestinal tract (paratyphoid, typhoid ) and biliary tract, with gynecological infectious diseases adults – 1.5-2 g 3 times a day or 1-1.5 g 4 times a day.

In severe infections (meningitis, septicemia), adults – up to 6 g per day in 3-4 doses. Children – 250-500 mg 3 times a day. The duration of treatment depends on the indications and the clinical picture and is usually 5-7 days. With otitis and similar infections in children, two-time administration of Amoxicillin is sufficient. In cases of chronic diseases, recurrent infections, severe infections currents adults appoint 750 mg-1 g three times a day for children up to 60 mg / kg per day divided into 3 doses.

When leptospirosis adults – 0.5-0.75 g 4 times a day for 6-12 days.

When listeriosis adults – 0.5 g 3 times a day for 6-12 days.

Side effects

Allergic reactions: urticaria, erythema (limited redness of the skin), Quincke’s edema, rhinitis (inflammation of the nasal mucosa), conjunctivitis (inflammation of the outer shell of the eye); Rarely – fever (a sharp rise in body temperature), joint pain, eosinophilia (an increase in the number of eosinophils in the blood); Extremely rare – anaphylactic (allergic) shock. It is possible to develop superinfections (severe, rapidly developing forms of an infectious disease caused by drug-resistant microorganisms that were previously in the body but do not manifest themselves), especially in patients with chronic diseases or reduced resistance (resistance) of the body.

Contraindications

Hypersensitivity to penicillins, infectious mononucleosis (acute viral disease, occurring with a high rise in body temperature, increase in palatine lymph nodes, liver).
Precautions prescribe the drug to pregnant women; Patients prone to allergic reactions. In patients who have increased sensitivity to penicillins, there may be cross-allergic reactions with cephalosporin antibiotics.