The Effects of Daily Bathing on the Symptoms of the Patients with Bronchial Asthma

Acronym

Bathing and Asthma

Scientific Title

The Effects of Daily Bathing on the Symptoms of the Patients with Bronchial Asthma

Scientific Title:Acronym

Bathing and Asthma

Region

Japan

Condition

Condition

bronchial asthma

Classification by specialty

Pneumology

Classification by malignancy

Others

Genomic information

NO

Objectives

Narrative objectives1

To investigate the situation concerning of the change of the symptoms and its degree by bathing in asthmatic patients.

Basic objectives2

Others

Basic objectives -Others

Also we investigated the relationship between the history of bathing-induced asthma exacerbation and that of paradoxycal bronchoconstriction.

Trial characteristics_1

Confirmatory

Trial characteristics_2

Explanatory

Developmental phase

Not applicable

Assessment

Primary outcomes

Frequency of exacerbation, improvement of asthmatic symptoms by bathing.

Key secondary outcomes

Frequency of paradoxycal bronchoconstriction in exacerbation group, impvoved group, and no change group of asthmatic symptoms by bathing.

Base

Study type

Observational

Study design

Basic design

Randomization

Randomization unit

Blinding

Control

Stratification

Dynamic allocation

Institution consideration

Blocking

Concealment

Intervention

No. of arms

Purpose of intervention

Type of intervention

Interventions/Control_1

Interventions/Control_2

Interventions/Control_3

Interventions/Control_4

Interventions/Control_5

Interventions/Control_6

Interventions/Control_7

Interventions/Control_8

Interventions/Control_9

Interventions/Control_10

Eligibility

Age-lower limit

15

years-old

<=

Age-upper limit

100

years-old

>=

Gender

Male and Female

Key inclusion criteria

Bronchial asthma who can properly answer the quetionnaire.

Key exclusion criteria

Those who cannot answer or denied to answer the quetionnarie.

Target sample size

250

Research contact person

Name of lead principal investigator

1st name

Middle name

Last name

Mitsuhiro Kamimura

Organization

National Hospital Organization Disaster Medical Center

Division name

Department of Pulmonology

Zip code

Address

Midorimachi3256, Tachikawa, Tokyo, Japan

TEL

042-526-5511

Email

tdmckamimura@yahoo.co.jp

Public contact

Name of contact person

1st name

Middle name

Last name

Mitsuhiro Kamimura

Organization

National Hospital Organization Disaster Medical Center

Division name

Department of Pulmonology

Zip code

Address

Midorimachi3256, Tachikawa, Tokyo, Japan

TEL

042-526-5511

Homepage URL

Email

tdmckamimura@yahoo.co.jp

Sponsor

Institute

National Hospital Organization Disaster Medical Center

Institute

Department

Funding Source

Organization

none

Organization

Division

Category of Funding Organization

Self funding

Nationality of Funding Organization

Other related organizations

Co-sponsor

Name of secondary funder(s)

IRB Contact (For public release)

Organization

Address

Tel

Email

Secondary IDs

Secondary IDs

NO

Study ID_1

Org. issuing International ID_1

Study ID_2

Org. issuing International ID_2

IND to MHLW

Institutions

Institutions

Other administrative information

Date of disclosure of the study information

2014

Year

11

Month

09

Day

Related information

URL releasing protocol

Publication of results

Partially published

Result

URL related to results and publications

Number of participants that the trial has enrolled

Results

Results: Two hundred and fifteen cases were recruited. Sixty cases (27.9%) experienced the appearance of the asthmatic symptom. The extent of the symptoms included 20 cases of chest discomfort (33.3%), 19 cases of cough (31.7%), and 21 cases of wheezing (35.0%). The triggering factors included vapor inhalation (32 cases, 53.3%), hydrostatic pressure on the thorax due to body immersion in the bathtub (26 cases, 43.3%), followed by sudden change of the air temperature (16 cases, 26.7%). Thirty-eight cases (17.7%) experienced the improvement of their active asthmatic symptoms by bathing. The vapor inhalation was the most common contributing factor (34 cases, 89.5%), followed by warming whole body (13 cases, 34.2%). There were no relationship between asthma severity and the appearance of the bathing-induced symptoms or improvement of active asthmatic symptoms by bathing.

Results date posted

Results Delayed

Results Delay Reason

Date of the first journal publication of results

Baseline Characteristics

Participant flow

Adverse events

Outcome measures

Plan to share IPD

IPD sharing Plan description

Progress

Recruitment status

Completed

Date of protocol fixation

2011

Year

12

Month

01

Day

Date of IRB

Anticipated trial start date

2012

Year

01

Month

01

Day

Last follow-up date

Date of closure to data entry

Date trial data considered complete

Date analysis concluded

Other

Other related information

Conclusion: The effects of bathing to asthmatic patients widely differed from patient to patient and its etiology includes several factors. For those who suffer from bathing-induced asthma symptoms, the preventive methods such as premedication of bronchodilators before bathing should be established.