Brentuximab vedotin has an
approximate molecular weight of 153 kDa. Approximately 4 molecules of MMAE are
attached to each antibody molecule. Brentuximab vedotin is produced by chemical
conjugation of the antibody and small molecule components. The antibody is
produced by mammalian (Chinese hamster ovary) cells, and the small molecule
components are produced by chemical synthesis.

What are the possible side effects of brentuximab vedotin (Adcetris)?

Some people receiving a brentuximab vedotin injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel nauseated, itchy, or if you have a fever, chills, cough, or trouble breathing during the infusion. Infusion reactions often occur within the first 24 hours after the start of your brentuximab vedotin infusion.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; wheezing, chest tightness, trouble breathing; swelling of your face, lips, tongue, or...