Series Parental Guide

nudity

Contains some moderate to strong sexual innuendo, as well as sex references and some mild to moderate scenes of kissing and sex, but no explicit nudity (only bare shoulders and backs are seen).
Dr. Cuddy often wears a low-cut top which Dr. House makes crude comments about. Dr. House also makes sexist remarks frequently about female colleagues and females in general.
One episode deals with the topic of rape, as one of House's patients is a victim. No depictions or graphic description of rape is present, but discussions of the after-effects are present.
Several episodes feature patients who are suffering from STDs.

violence

Occasional mild violence such as punching between the colleagues of the hospital.
Some episodes contain strong violence and fighting which lead to bloody injuries.
Most, if not all, episodes contain strong depictions of injuries and surgery, with internal organs and gruesome side-effects of diseases shown and described in detail.

profanity

Dr. House is often very rude to his colleagues and his patients.
Crap, ass and damn are very commonly used, with bitch, piss and slut also used frequently. There is also occasional uses of bastard, whore and dick.
There is very frequent religious exclamations (such as "Oh my God" and "For God's sake") and anatomical terms, but these are more often than not used in a medical context.

alcohol

Social drinking is seen occasionally. Some episodes show some of the characters getting drunk for various reasons. Some people are seen occasionally smoking, including (albeit very rarely) House himself.
An ever-present feature of the show is House's addiction to hard drugs (pain medication called Vicodin which he takes because of chronic pain in his leg). He is frequently seen taking these drugs and bragging about his addiction, and several episodes graphically depict him detoxing from the drug. House is also seen to take cocaine and heroin in a few episodes, as well as some other experimental medication.
Frequent discussions about drugs in relation to patient's symptoms. Several episodes centre around patients whose symptoms are caused by drug use, which are discussed in detail.

frightening

Characters often face moral dilemmas as they weigh the diagnosis and care of a patient vs. violating the rules and working outside the system in order to do so. Ethical questions regarding these decisions are often discussed.
Surgery scenes can be extremely graphic and gory and sometimes very intense.
In almost every episode, patients can be seen having seizures, vomiting blood or something similar whilst doctors or people around them attempt to help, which can be very intense sometimes.
Discussions about death, rape and other sensitive mature topics are frequent. There are also episodes which depict suicide and suicide techniques.