Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cymbalta (duloxetine) is good for treating depression, anxiety, and some forms of chronic pain, but it is more likely than other antidepressants to cause problems if you drink alcohol or have high blood pressure.

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3.6/ 5 average rating with 496 reviewsforCymbalta

Controls seizures and helps panic attacks.

Klonopin (clonazepam) can be used for immediate relief of panic attacks and seizures, but is not intended for long-term management.

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3.8/ 5 average rating with 767 reviewsforKlonopin

Upsides

Cymbalta (duloxetine) may help relieve nerve pain from diabetes and other forms of chronic pain.

Cymbalta (duloxetine) has several uses, which may be good for people with multiple conditions.

Available as a generic, which is cheaper.

More people who took Klonopin (clonazepam) were free of panic attacks, compared to people who did not take Klonopin (clonazepam).

Klonopin (clonazepam) works quickly, within the hour.

Can be used together with antidepressants to manage panic disorder.

Klonopin (clonazepam) lasts longer and has less severe withdrawal symptoms compared to other similar medicines.

Downsides

Cymbalta (duloxetine) may not be a good option if you're a heavy drinker, or have liver or kidney problems.

Cymbalta (duloxetine) can increase high blood pressure.

Like most antidepressants, Cymbalta (duloxetine) can cause higher risk of suicidal thoughts and behavior for people aged 24 and younger.