Angiex’s Upcoming Mission on the International Space Station

I think most of you know that the reason we haven’t been posting much the last three years is that Shou-Ching and I launched a biotech company, Angiex, in 2015 with the goal of creating a breakthrough cancer therapy.

Our drug is close to being finalized, and it is performing remarkably well. We have effectively regressed every tumor we’ve tested in rodents. There is good therapeutic margin in both mice and rats, and the drug is well tolerated in monkeys. There’s every reason to be optimistic it will do well in humans. There’s also reason to believe it will effectively treat the most malignant cancers, such as pancreatic cancer and liver cancer. The more aggressive the cancer, the better our drug works.

CASIS came to our laboratory at LabCentral in Cambridge, Massachusetts, and made a very nice video explaining our experiment and some background about Angiex. We’re excited to share this glimpse at Angiex’s work. Enjoy!

20 Comments.

Just today I found that my 2x breast cancer, 9 and 7 years ago respectively, has metastasized into bone and lung cancer. I eagerly await your treatment – hurry! I have lots to do and much life to love.

You guys are literally incredible. I am so lucky to have discovered your work.

But: there is no way the elite-corporate power structure is going to allow a cancer-curing drug to gain mass acceptance. It would see off too many industries.
Guys please please protect yourselves. I see intimidation, discrediting and perhaps threats to your lives if this goes too far.

I *hope* I’m being cynical and conspiracy theorist-like. But I don’t think I am.

We are thankful for your work…when will human trials be available?
Also, I’m trying the ketogenic version of your diet. Can you briefly explain why you suggest NAC and branch chain aminos with this plan?

Human Phase 1/2 trials will probably run from late 2020 through late 2023.

Branch chain amino acids – several are ketogenic, they may also support retention of muscle on a low-carb/low-protein diet. Re NAC, I don’t recall where I linked that to ketogenic diets, but it is appropriate in many therapeutic situations for which people might want to try a ketogenic diet, e.g. migraines. Indeed glutathione synthesis which NAC supports has been hypothesized to be one of the avenues of clinical benefit from a ketogenic diet, e.g. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692867/.

I’m commenting here to ask for suggestions (in the interim, while we await the release of your cancer treatment) for a friend’s aunt who was diagnosed with pancreatic cancer 2 weeks ago. She was told she could get up to a year with chemo, four months without. She started her first chemo treatment last Wednesday but they were only able to do half because her platelets were so low. A few days later she went to the hospital where the found out her liver is now shot and they will no longer be able to give chemo. So at this point they are saying she has one week to live.

I don’t know this family well and have never met her aunt, but I wanted to give them any bits of hope I can. My first thought was you guys! I never want to burden you all because I know you are so busy with research and getting this new treatment going, but aside from your diet, are there a few major bulletpoints I could pass on to her?
Fasting?
Vitamins D, Iodine, Vitamin C?
Anti-cancer herbs?
Ketogenic diet maybe?
Thank you all so much for all you do!
So grateful!
KH

All the PHD stuff, circadian rhythm entrainment, intermittent fasting, vitamin D, iodine, vitamin C, will be good. But given the short time frame, her best chance of survival, though for pancreatic it is remote, is to activate the immune system against the cancer. She should ask her doctor for anti-PD-1 (Opdivo, Keytruda) and anti-CTLA-4 (Yervoy) antibodies and also consider immune-activating supplements like beta glycans or maybe something like this: https://www.amazon.com/gp/product/B07CF55GLC/ref=ox_sc_act_title_1?smid=A2E9HURFSSQR50&psc=1.

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