The late-night host will lead the annual awards ceremony on Sunday, April 13 at 9 p.m. ET/PT on MTV, broadcast live from L.A. Live's Nokia Theatre in Los Angeles. O'Brien made the announcement on Tuesday's episode of his TBS talk show, Conan.

“After eight years of intense negations, I am honored to announce I am hosting MTV’s second most prestigious awards show," joked O'Brien, who hosted the Emmys in 2002 and 2006 (he was a co-host in 2003).

The MTV Movie Awards traditionally kicks off the summer movie season, with the Viacom-owned network promising "another epically funny, explosive, over-the-top show." The awards show will recognize best movies and performances from the past year and will also debut exclusive footage from anticipated summer blockbuster releases.

Nominees will be revealed Thursday, March 6 at 4 a.m. PT/7 a.m. ET at www.MTVMovieAwards.MTV.com.

MTV Networks will broadcast the awards across its international portfolio, which features more than 60 channels.

Last year marked the first time the MTV Movie Awards moved from its post-Memorial Day date to April, with 3.8 million viewers tuning in on MTV. (About 4.8 million watched across all Viacom networks, including VH1, MTV2 and Logo.)

Jesse Ignjatovic, Lee Lodge and Jen Jones serve as executive producer with MTV's Garrett English. Wendy Plaut is co-executive producer and executive in charge of celebrity talent, with Amy Doyle as executive in charge of music and celebrity talent. Joanna Bomberg is executive in charge of music talent.