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Advanced Analytical Chemistry - Chromatography and Mass
Spectrometry

Course content

Today, chromatography and mass spectometry is by far the most
common used analytical techniques. A thorough understanding of the
chromatographic theory, and operating mechanism of ionisation
techniques and mass analysers is essential for method selection,
development and optimisation.

The course covers chromatographic separation of organic compounds
with special emphasize on the molecular mechanism and theory of
analyte-column interactions for gas and liquid chromatography, and
the theory of ionization, fragmentation, mass separation, detection
and data-analysis for all kind of mass spectrometers and ionization
techniques in common. All common analytical instruments and
techniques from GC-FID/MS to UPLC-UV/FLU/MSMS are addressed. The
theory is supplemented with computer simulations and expert
guest-lectures of selected topics.

Competences - The student can be considered a:
-Matured analytical chemist with the ability to sketch, develop,
implement, maintain and evaluate any chromatographic mass
spectrometric method for analysis of complex
mixtures.