While taking magnesium salicylate, avoid using aspirin or other aspirin-like products (other salicylates). Ingesting too much aspirin can be dangerous.

Magnesium salicylate, when taken with other medicines, may cause the effects of either drug to alter, decrease or increase. Such interactions are possible between magnesium salicylate and the following: anti-gout drugs like probenecid (Benemid, Probalan), any drugs, antacids or supplements that contain magnesium, aspirin, barbiturates like secobarbital (Seconal), blood thinners like warfarin (Coumadin), diuretics like spironolactone (Aldactazide, Aldactone), methotrexate (Rheumatrex, Trexall), NSAIDs (nonsteroidal anti-inflammatory drugs) and other pain relievers, oral diabetes drugs, phenobarbital and phenytoin (Dilantin). Also, you should avoid getting pregnant while using this drug.

This drug works similarly to aspirin, which can increase risk of a stillbirth or death soon after birth. This drug could also cause pregnancy to extend or it could lengthen the labor process. Using this drug in the last trimester can cause fatal lung damage to a fetus. You also may wish to avoid breastfeeding while using this drug, as it can be passed to a nursing baby through breast milk.