2007年8月17日 星期五

何謂敗血症？

Sepsis:Sepsis is systemic infection accompanied by a reaction that has been termed the systemic inflammatory response syndrome (SIRS). SIRS represents an acute inflammatory reaction with systemic manifestations caused by release into the bloodstream of numerous endogenous mediators of inflammation. SIRS can also be caused by acute pancreatitis and major trauma, including burns. It has previously been defined by 2 or more of the following:

However, these criteria are now viewed as suggestive but not sufficiently precise to be diagnostic.Severe sepsis:Severe sepsis is sepsis accompanied by signs of failure of at least one organ. Cardiovascular failure is typically manifested by hypotension, respiratory failure by hypoxemia, renal failure by oliguria, and hematologic failure by coagulopathy.

Septic shock:Septic shock is severe sepsis with organ hypoperfusion and hypotension that are poorly responsive to initial fluid resuscitation.