La citazione di Kirk riportata sotto «All I ask is a tall ship, and a star to steer her by» è tratta da Sea Fever di John Masefield:
«I must go down to the seas again, to the lonely sea and sky,
And all I ask is a tall ship and a star to steer her by,
And the wheel's kick and the wind's song and the white sail's shaking,
And a grey mist on the sea's face and a grey dawn breaking.

I must go down to the seas again, for the call of the running tide
Is a wild call and a clear call that may not be denied;
And all I ask is a windy day with the white clouds flying,
And the flung spray and the blown spume, and the sea-gulls crying.

I must go down to the seas again, to the vagrant gipsy life,
To the gull's way and the whale's way where the wind's like a whetted knife;
And all I ask is a merry yarn from a laughing fellow-rover,
And quiet sleep and sweet dream when the long trick's over.»
La stessa frase diventerà anche il motto della Defiant.

McCoy: We're all sorry for the other guy when he loses his job to a machine, but when it comes to your job... that's different. And it always will be different. [T:08:13]

Kirk: Granted, it can work a thousand, a million times faster than the human brain, but it can't make a value judgment, it hasn't intuition, it can't think. [T:14:49]

Kirk: Machine over man, Spock? It was impressive. Might even be practical.Spock: Practical, Captain? Perhaps, but not desirable. Computers make excellent and efficient servants, but I have no wish to serve under them. Captain, a starship also runs on loyalty to one man and nothing can replace it or him. [T:18:13]

Kirk: «All I ask is a tall ship, and a star to steer her by.» You could feel the wind at your back, about you... the sounds of the sea beneath you. And even if you take away the wind and the water, it's still the same. The ship is yours, you can feel her, and the stars are still there, Bones... [T:21:15]

Kirk: That wasn't a minor difficulty. That wasn't a robot. That thing murdered one of my crewmen and now you tell me that you can't turn it off?Daystrom: It wasn't a deliberate act. M-5's analysis told it needed a new power source. The Ensign... simply got in the way.Kirk:: And how long will it be before all of us «simply get in the way»? [T:25:42]

Spock: Of course, the M-5 itself has not behaved logically.McCoy: Please, Spock, do me a favour. And don't say it's fascinating.Spock: No. But it is... interesting. [T:27:05]

Daystrom: When a child is taught... it's programmed with simple instructions -and at some point, if its mind develops properly, it exceeds the sum of what it was taught, thinks independently. [T:27:51]

Kirk: Genius doesn't work on an assembly line basis. You can't simply say «Today I will be brilliant.» [T:29:51]

McCoy: If a man had a child who'd gone anti-social, killed perhaps, he'd still tend to protect that child. [T:30:23]

Spock: Every living thing wants to survive. [T:41:40]

McCoy: Compassion. That's the one thing no machine ever had. Maybe it's the one thing that keeps men ahead of them. Care to debate that, Spock?Spock: No, Doctor. I simply maintain that computers are more efficient than human beings. Not better. [T:46:31]