[EN] Although nasal carriage has been described as a risk factor for Staphylococcus aureus infections in humans, there is a scarcity of studies about S. aureus nasal carriers in animals. In rabbits, S. aureus is one of the ...[+]

[EN] Although nasal carriage has been described as a risk factor for Staphylococcus aureus infections in humans, there is a scarcity of studies about S. aureus nasal carriers in animals. In rabbits, S. aureus is one of the most important pathogens responsible for a number of different types of infections. This study was designed to determine the extent of staphylococcal nasal carriage and to establish whether a relationship exists between nasal carriage and development of lesions. One hundred and sixteen rabbits with and without chronic signs of staphylococcosis from 6 industrial rabbitries were monitored. Nasal swabs for microbiological assessments were obtained from all animals. Microbiological results showed that 56% of the animals carried S. aureus in their nasal cavities with significantly higher incidence in animals with staphylococcal-related lesions (84.2%) compared to apparently healthy animals (28.8%). Additionally, the S. aureus strains isolated from the nasal cavity and lesions were clonally related in 91.7% of animals. This suggests that nasal carriage of S. aureus in rabbits could be a risk for development of clinical infections.[-]

This study was supported by the Inter-ministerial Commission for Science and Technology (CICYT) of the Spanish Government (AGL2011-30170-C02-02 and AGL2014-53405-C2-2-P). The authors acknowledge Dr. E. A. Gomez for the ...[+]

This study was supported by the Inter-ministerial Commission for Science and Technology (CICYT) of the Spanish Government (AGL2011-30170-C02-02 and AGL2014-53405-C2-2-P). The authors acknowledge Dr. E. A. Gomez for the statistical analysis and Prof. Sean (J.J) Callanan for revision of the manuscript.[-]