• when newly exposed to the arena, mice exhibit a moderate increase in locomotor activity to 119% of wild-type mice

• mice exhibit increased exploratory behavior under stressful conditions of an open field and in the spontaneous alteration test (58.9+/-2.2 visits to the arms compared to 47.2+/-1.6 visits to the arms for wild-type mice)

• mice exhibit a decrease in spontaneous alternations in a Y maze (53.7+/-1.9% compared to 61.4+/-1.8% for wild-type mice)

• however, the number of entries and time spent in the open arms in an elevated plus maze are normal