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Carbapenems

Carbapenems are one of the most important classes of antibiotics used in humans, and are an important agent against multi-drug resistant bacteria. Now, for the first time, bacteria that carry a transmissible carbapenem resistance gene have been found in agricultural animals ...More

Carbapenemase-producing Enterobacteriaceae (CPE) have become a major problem for healthcare systems worldwide. While the first reports from European hospitals described the introduction of CPE from endemic countries, there is now a growing number of reports describing ...More

Antibiotic resistance is poised to spread globally among bacteria frequently implicated in respiratory and urinary infections in hospital settings, according to new research at Washington University School of Medicine in St. Louis. The study shows that two genes that confer ...More

The role of the hospital environment in transmission of ESBL-Klebsiella pneumoniae (ESBL-KP) and ESBL-Escherichia coli (ESBL-EC) is poorly defined. Recent data however suggest that in the hospital setting, ESBL-KP is more transmissible than ESBL-EC. Freeman, et al. (2014) ...More

Orally administered, nonabsorbable antibiotics were effective in eradicating carbapenem-resistant Enterobacteriaceae (CRE) colonization, according to a new study published in the December issue of the American Journal of Infection Control. Researchers at Rambam Health Care ...More

As public health authorities across the globe grapple with the growing problem of antibiotic resistance, Tufts University School of Medicine microbiologists and colleagues have identified the unique resistance mechanisms of a clinical isolate of E. coli resistant to ...More

Patients who tested positive for carbapenem-resistant Enterobacteriaceae (CRE) took an average of 387 days following hospital discharge to be clear of the organism, according to a new study published in the March 2013 issue of the American Journal of Infection Control. The ...More

The emergence of Klebsiella pneumoniae carbapenemases (KPCs) producing bacteria has become a significant global public health challenge while the optimal treatment remains undefined. Lee and Burgess (2012) performed a systematic review of published studies and reports of ...More

Antibiotics kill bacteria, not viruses. Viruses, which antibiotics do not affect, cause 9 out of 10 sore throats and 10 out of 10 cases of influenza. Taking antibiotics unnecessarily weakens their ability to work against infections when they are needed. This enables ...More