Chorionic gonadotropin cost

PREGNYL® (chorionic gonadotropin for injection USP) is a
highly purified pyrogen-free preparation obtained from the urine of pregnant
females. It is standardized by a biological assay procedure. It is available
for intramuscular injection in multiple dose vials containing 10,000 USP units
of sterile dried powder with 5 mg monobasic sodium phosphate and mg dibasic
sodium phosphate. If required, pH is adjusted with sodium hydroxide and/or
phosphoric acid. Each package also contains a 10-mL vial of solvent containing:
water for injection with % sodium chloride and % BENZYL ALCOHOL, WHICH
IS NOT FOR USE IN NEWBORNS. If required, pH is adjusted with sodium hydroxide
and/or hydrochloric acid.

Hyperplasia of testicular Leydig cells and ovarian theca-lutein cells is a common histologic finding in infants of diabetic mothers. The functional correlates of this histologic finding were investigated by measurement of the beta-subunit of human chorionic gonadotropin, testosterone, dihydrotestosterone, androstenedione, estradiol, and estrone in the amniotic fluid compartment of gestations with male and female fetuses in diabetic mothers (N = 34) and control women (N = 34) at term. When compared with those of control subjects, gestations of diabetic mothers had significantly higher amniotic fluid concentrations of the beta-subunit of human chorionic gonadotropin. Gestations with either male or female fetuses in diabetic mothers had significantly higher amniotic fluid testosterone and dihydrotestosterone levels when compared with those of their respective gender controls. In gestations with male fetuses in diabetic mothers there was a significant positive correlation between the beta-subunit of human chorionic gonadotropin and testosterone. There was no significant difference in amniotic fluid androstenedione, estradiol, or estrone levels between the gestations of diabetic mothers and those of control women. These results suggest that the testicular Leydig cell and ovarian theca-lutein cell hyperplasia seen in infants of diabetic mothers is due, in part, to elevated levels of human chorionic gonadotropin and is associated with elevated testosterone and dihydrotestosterone concentrations in the amniotic fluid.