Friday, July 21, 2006

The return of the deads.

The Neandertal'sbones (left), are stronger than of Homo sapiens sapiens(right). Drawing, Courtesy 454 Life Sciences. To see better, click and enlarges.

The swedish researcher http://www.454.com/downloads/news-events/CV_Paabo.pdfSvante Pääbo of the Max Planck Institute, of Evolutionary Biology (Leipzig, Germany), with the aid of the American company: 454 Life Sciences (that http://www.454.com/news-events/press-kit-20060719.asp has developed a DNA secuential/decodificating machine, practical and speedy), prepare to attack a cyclopean task (predicted by us, in 2005) : The return of the dead : dinosaurs, mammoths, what you desire including dead persons, in this case, of ours cousins: the Neandertals [(of the ones most believed are product of geographical isolation of Homos erectus archaic: (1,9 Ma-400 000 years b.C)], some robust and rude men that inhabited Europe among the 300 000 -30 000 years b.C, according to macrofósils remains. Pääbo a swedish of large goals said that when the cells die, http://www.nytimes.com/2006/07/21/science/21neanderthal.html?_r=1&oref=slogin the DNA splits itself in pieces, although not to extreme to do impossible its identification and secuenciation. With lengths of 100 pairs of bases (pb), is possible to identify them. Pääbo, that already has reconstructed partial sequences of DNA of mammoths and prehistórics bears, knows that with samples of bony remainders, is possible to arrange DNA of Neandertals. It can be done it even with only one chromosome, but if a piece were insufficient, sufficed with analyzing remainders of others Neandertals. With that way we wait to reconstruct a sequence of 3 trillion pairs of bases.

At to culminate the secuenciatión of the genome of the Neandertals, the humanity will have 3 complete genomes: that of the chimp, that of the Neandertal and that of the Homo sapiens sapiens. The comparisons and differentiations of genetic sequences among them, will open new avenues to evolutionary biology. By the moment, Paabo said that in the human genome he has identified the genes ; FOXP-2 (language) and that they functionally resemble mutated genes or variant of genes FOXP-2, of chimp. There is hope of identifying these genes in the genome of the Neandertal, being expected that they explain how emerged the language in the humans. Also it will be important to identify the genes that conditioned the growth and the special form of our brain. Finally when the genome is completed, facilitated by the 454 Life Sciences, machine, then most scientific expects to insert the complete genome of the Neandertal in human donated ovum, being expected to have for the 2010, the alive Neandertal again among us. Subsequently, we will insert reconstructed genomes of dinosaurs (obtained also of bone), in the interior of promoted ovums (with more energy), of salamanders, being obtained finally a gang of dinosaurs to be lodged in a welcoming Jurassic park. In the same way the reconstructed genome of dead persons. Do not worry about dinosaurs, the systems of security will be so advanced that it will be impossible that they attack us. This is a kind of projections that this kind of investigations give us.