Target details

Target details

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Alternative Name

BRUNOL6 / CELF6

Background

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.Synonyms: BRUNOL-6, Bruno-like protein 6, CELF-6, CUG-BP- and ETR-3-like factor 6