THROMBOCYTOPENIA and ACTIQ

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THROMBOCYTOPENIA Symptoms and Causes

Platelets are little pieces of blood cells. Platelets help wounds heal and prevent bleeding by forming blood clots. Your bone marrow makes platelets. Problems can result from having too few or too many platelets, or from platelets that do not work properly.

If your blood has a low number of platelets, it is called Thrombocytopenia. This can put you at risk for mild to serious bleeding. If your blood has too many platelets, you may have a higher risk of blood clots. With other platelet disorders, the platelets do not work as they should. For example, in von Willebrand Disease, the platelets cannot stick together or cannot attach to blood vessel walls. This can cause excessive bleeding.

THROMBOCYTOPENIA Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.

The primary measure will be the change recorded in patients subjective pain using a standardized scale; Change in patients vital signs: blood pressure, respiratory rate, heart rate, pulse oximetry will be monitored at 5 and 10 minutes following Atomized Fentanyl

AE Profile; To characterize the safety of Fentanyl TAIFUN treatment vs. the current BTP treatment based on the AE profile; To estimate the proportion of patients taht can be titrated to an effective dose of Fentanyl TAIFUN; To evaluate the efficacy of Fentanyl TAIFUN with the titrated dose and the current BTP treatment with the confirmed dose; To evaluate patients's preference between Fentanyl TAIFUN and the baseline BTP medication; To evaluate the sustained analgesic effect of Fentanyl TAIFUN and the current BTP treatment

If you think you may have a medical emergency, call your doctor or 911 immediately.

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