Smart adventurers boil their drinking water, splash alcohol on their battle wounds and check their potential romantic conquests for boils and sores because of hard-taught lessons. No matter how mighty or experienced the character, an illness can lay him low. Diseases can’t be fought and often can’t be avoided, considering the risks that come with the adventuring lifestyle. Heroes and villains alike have good reasons to fear this collection of two dozen diseases for the Pathfinder Roleplaying Game.