Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.

Predicted Target Size

61 kDa (note)

Positive Controls

A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse liver

Form Supplied

Liquid

Concentration

0.85
mg/ml
(Please refer to the vial label for the specific concentration)

Purification

Purified by antigen-affinity chromatography.

Specifications: NCOA62 antibody [N3C3]

Full Name

SNW domain containing 1

Product Description

Rabbit Polyclonal antibody to NCOA62 (SNW domain containing 1)

Background

This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. [provided by RefSeq]