In this recent post to the Nodeable Blog, they suggest that the days of the typical LAMP stack (Linux, Apache, MySQL, PHP) are numbered because of what many of the cloud services have to offer.

For the past 10 years, the LAMP stack has laid waste to proprietary software stacks. Yes, Microsoft has held onto gargantuan profits, but LAMP has become the foundation for leading web services, whether Google or Facebook or [Insert Big Web Brand Here]. LAMP is the future. Or was. That is, until cloud killed it, as Eucalyptus CEO (and former MySQL CEO) Marten Mickos posits in a great keynote from the Percona Live: MySQL Conference & Expo 2012.

In the keynote he pointed out that it's becoming less about the whole setup and more about combining technologies to get the results you need - less "stack" and more "linked technology" (and not always the same tech for every node). He pointed to the Amazon AWS service as a prime example of a platform that allows endless flexibility as to what software can be installed and how it can be used, all with a few clicks of a mouse.