EXCLUSIVE: Carla Gugino and Bruce Greenwood have been set to star in Gerald’s Game, an adaptation of the Stephen King 1992 bestselling novel that Mike Flanagan will direct from a script he wrote with Jeff Howard. Netflix will release globally. Intrepid Pictures’ Trevor Macy will produce. Flanagan, who most recently helmed Hush, next has Ouija: Origin Of Evil for Universal.

Henry Thomas, Carel Struycken, Kate Siegel, and Chiara Aurelia round out the cast as production gets underway in Mobile, AL. Gerald and Jessie Burlingame head to their summer home on a warm weekday in October for a romantic interlude that involves adult games. After being handcuffed to her bedposts, Jessie tires of her husband’s games, until things take an unexpectedly tragic turn. She’s left handcuffed, trapped and alone as painful memories from her childhood bedevil her. Her only company is a hungry stray dog, the voices that populate her mind, and possibly someone watching her from the corner of the dark bedroom.

“Gerald’s Game has been my dream project for nearly 20 years,” Flanagan said. “As a lifelong fan of Stephen King, it is a true honor to be trusted with this amazing material. I am deeply grateful to my longtime partner, Trevor Macy, and to my new partners at Netflix, for making this dream project a reality. This is one of the reasons I wanted to make movies in the first place.”

This is Macy and Flanagan’s fifth collaboration after Oculus and Before I Wake for Relativity; Hush for Netflix; and Ouija: Origin of Evil, which Universal will release Friday. Intrepid product also includes the Stacy Title-directed The Bye Bye Man, which STX releases January 13.

Gugino is represented by CAA and Untitled, Greenwood by Gersh, Thomas by Gersh and Brillstein Entertainment Partners, Struycken by Jeffrey Leavitt Agency, Siegel by TCA/Jed Root and Nelson Davis, Aurelia by Paradigm, Flanagan by WME, and King by Paradigm.