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Michael tries to save his brother and himself from the unstoppable Mahone. Kellerman's testimony at Sara's trial proves different from what was expected. Sucre puts everything on the line to save Maricruz.
Just like old times, T-Bag and Bellick are at it again.

The day has finally come for Sara's trial.
Michael is determined to stop T-Bag's reign of terror.
Bellick is money hungry and will do whatever it takes to hunt down T-Bag. Kellerman decides his fate while Lincoln and Mahone square off.

Sara sacrifices herself for the safety of Michael so the brothers can get on with their final plan to attain freedom, but their plan gets 'shipwrecked'. Meanwhile, Bellick blackmails Sucre to partner up as T-Bag's streak of murder continues to the south of the border.

An unlikely alliance forms between Bellick and Sucre while Michael is determined to face the president.
T-Bag gets into some trouble when he loses his luggage.
C-Note faces major consequences after some of his actions.

T-Bag digs deep and finds his 'nice-side' with the help of a psychiatrist.
Michael, Lincoln, and Sara get their hands on evidence needed to clear Lincoln, while Kellerman is close to finding the President.

Michael and Sara request Henry Pope's help in retrieving the information that could possibly exonerate Lincoln.Mahone pins down an escapee.Sucre discovers a new threat while hitchhiking to reunite with Maricruz.T-Bag brings the Hollander family to his home.

Bellick gets a taste of the medicine he gave out when he was the captain at Fox River.Agent Mahone's ex-wife makes another appearance, as Mahone is forced to make a difficult decision.Kellerman reveals his motivation for aiding the escape.T-Bag rekindles an old romance.

Bellick is anything but happy about his sudden homecoming-to Fox River.Elsewhere, Michael and Lincoln might face a homecoming of their own. Mahone and Kellerman use everything they have to make certain that Michael and Lincoln do not get through their road trip alive.Sucre's getaway plane encounters some difficulties.T-Bag closes in on Mrs. Hollander.moreless

In an effort to learn more about his pursuer Michael cozies up to Mahone's wife. L.J. and Lincoln have a bumpy road-trip. T-Bag receives a surprise, and C-Note's wife must choose between her daughter and husband.

Michael, Sucre, T-Bag and C-Note claim the hidden treasure.An anxious Lincoln risks everything to get to LJ. Kellerman rethinks where his loyalties lie after Sara gets to The Company's hit list.Mahone resorts to deadly force to get the truth out of Tweener.

Mahone takes an interest in the story of DB Cooper.
In their quest to find Westmoreland's treasure, Michael and Lincoln travel house-to-house in Utah.
Haywire's journey outside the prison walls continues.
Sucre bumps into an acquaintance.

Michael and Lincoln are eager to locate the Double K ranch where Westmoreland hid his millions.
Sucre goes to Las Vegas to prevent Maricruz from marrying his cousin Hector. C-Note gets on a train.
Mahone is given an important package.

Bellick sets out to find the money stolen by Westmoreland during the 1971 skyjacking.
Kellerman targets Sara, who receives a long-awaited phone call.
T-Bag gets a ride from an unsuspecting family.
Abruzzi resumes the search for Fibonacci to settle the scores once and for all.

Michael and a wounded Lincoln try to outmaneuver Mahone, who is hot on their trail. Sara gets a surprise visit to her bedside.Following his termination, Bellick recruits a resolute partner to aid in his quest to get the escapees behind bars.Sucre and C-Note head out for their family reunions-regardless of being observed by the authorities.moreless

Mahone tries to lure the brothers by targeting an imprisoned LJ. Sucre, Abruzzi and C-Note have a plan of their own, but only to break free of their pursuers. Meanwhile, Bellick and Warden Pope feel the heat following their unsuccessful attempts to capture the escapees. Tweener infiltrates a bunch of college students on their way to spring break.moreless

Eight hours have passed since the escape. Michael, Lincoln, Sucre, C-Note and Abruzzi continue to evade their pursuers. Bellick is forced to relinquish command of the search party to FBI Special Agent Alexander Mahone whose ingenious approach makes Michael's life as a fugitive harder. As a result from her overdose, Dr. Tancredi is in critical condition. A short-handed T-Bag faces the ultimate challenge.moreless

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