Main navigation of MELANOCYTE PATHOLOGY.COM

Clinical information

Diagnosis:

Spitz tumour of uncertain malignant potential (STUMP)

Comments:

STUMP WITH DEEP NODULAR COMPONENT IN CHILDREN

Some Spitzoid melanocytic proliferations of prepubertal children present with deep, miotitcally active nodules bulging into the deep dermis or even subcutis. Spread to regional lymph nodes is seen repeatedly and to those who regard spread to a regional node as formal proof of malignancy, this means that these lesions are (spitzoid) melanomas. Ohers have pointed out that children with such tumors and nodal deposits do remarkably well, and that distant metastasis appears to be very rare, much rare than one would expect in case of thick melanoma NOS with a positive regional lymh node. For te time being, I therefore regard these lesions as STUMP (Spitz tumor of uncertain malignant potential). Hopefully, future work and clinical experience will shed more light on this issue.

Tell a friend:

Tell a friend

Dear {friend_name},
{url}
I believe this website may be of interest to you. It is an Open Educational Resource, containing a large collection of digitized histologic slides with explanatory films and other materials, aimed at surgical pathologists, dermatopathologist and pathologists in training. This site is entirely based on consultation materials of professor Wolter Mooi, VU University Amsterdam, and can be used free of charge.
Kind regards,
{my_name}