I would like to know the microbiological standards for surface cleaning validation. could you help me please!!!!!

best regards,

ismahane.

prashant.chawla

09-10-2010, 06:27 AM

Dear ismahane,
As per my knowledge, The monitoring of microbial load after cleaning is not that criticial if you are doing Steam Sterilization post cleaning. Provided your Sterilization is validated. I have till date not come across of monitoring microbial load with swab. If your final rinse during CIP is with WFI, I would recommend to check the final rinse sample to compare with WFI bioburden specificiation i.e. 10CFU/100ml.
I hope I have tried to clear your doubt.

Let me know if you need more.

All the best.:)

cs2009

09-10-2010, 06:45 PM

Microbial limit for Non-sterile products shall be calculated based on the product specific requirement. you can use the following equation: