The Vogue editor-in-chief, a longtime friend of the disgraced film mogul, says her heart goes out to all the women who have come forward, as well as to Georgina Chapman.

The Vogue magazine editor-in-chief and Conde Nast artistic director, who was often seated next to Weinstein in the front row of Marchesa runway shows, has at last addressed the disgraced film mogul's alleged sexual misconduct as more women continue to come forward.

"Behavior like this is appalling and unacceptable," Wintour said in a statement provided by a Vogue spokeswoman Friday.

"I feel horrible about what these women have experienced and admire their bravery in coming forward. My heart goes out to them, as well as to Georgina [Chapman] and the children," she continued. "We all have a role to play in creating safe environments where everyone can be free to work without fear."

Wintour and Weinstein have been friends and collaborators for more than a decade, co-hosting film screenings together, as well as political fundraisers for former President Barack Obama. Weinstein and his wife, Marchesa designer Chapman, have been regulars at Vogue's annual Metropolitan Museum of Art Costume Institute Gala, too.

Wintour's statement comes a little more than a week after The New York Times published its explosive exposé, in which Ashley Judd and other women provided detailed accounts of the producer's sexual harassment, which was followed days later by The New Yorker posting Ronan Farrow's investigative report with women leveling sexual assault and rape claims.

Late Thursday evening, model and TV host Heidi Klum spoke out about the former Project Runway producer. "I truly admire these brave women who are coming forward to share their stories because change cannot come unless there is a dialogue and people are held accountable," said Klum in a statement to People. "I wish I could say that the horrible stories I read about Harvey Weinstein are a rare occurrence in our society, but that is simply not the case. We would be naive to think that this behavior only happens in Hollywood."