AREDS vs. AREDS2
In 2001, the National Eye Institute, part of the National Institutes of Health, completed the Age Related Eye Disease Study (AREDS), which showed that ingesting high levels of specific nutritional supplements decreased the risk of macular degeneration (AMD) progression. This included 25,000IU of Vitamin A , 500 mg of Vitamin C, 400 IU of Vitamin E, 80 mg of Zinc and 2 mg of Copper.
While AREDS was the first study demonstrating benefit against this retinal eye disease, if failed to demonstrate improvement in vision. More recent studies, including the Lutein Antioxidant Supplement Trial, have demonstrated vision improvement, something AREDS could not. And much exciting work involving both Lutein and Zeaxanthin, molecules known as carotenoids, have shown not only vision improvement but also a healthier macular appearance.

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