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Due to the potential for decreased renal function in elderly subjectsthe metformin dosage should be adjusted based on renal functionRegular assessment of renal function is necessarysee section 4.4

Metformin can cause changes in the menstrual cyclepromote ovulationand increase the risk of becoming pregnantConsult your doctor or pharmacist about the use of reliable birth control while using this medication.

Older adults may be at greater risk for side effects such as low blood sugar or lactic acidosis.

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