Starring: Will Arnett and Christina Applegate as new parents Chris and Reagan; Maya Rudolph as Ava, Reagan’s talk show host boss; and Nick Cannon as Ava's talk show co-host

What It’s About: Yes, we’ve all seen new parents struggling to balance it all and still have their own lives … but never like this. Arguably the best, funniest and most natural roles for all three stars. We'll have to wait and see how new addition Cannon fits into the mix.