In 1868, a man named Eben Frost redeems a medal from a pawn shop and delivers it to a widow, Elizabeth Morton (Betty Field). Twenty years earlier her late husband W.T. Morton had used anesthesia on Frost for a dental procedure.

Flashback two decades, Morton (Joel McCrea) and his wife marry and he struggles in dentistry. Learning of Letheon (ether) from fellow dentist Horace Wells (Louis Jean Heydt), he successfully applies it in his practice for painless tooth extraction. Surgeons are interested but skeptical and want to know the composition. In keeping the simple formula a secret, Morton could become wealthy, but he is prompted to reveal its composition when confronted with a little girl bravely awaiting an operation.

Losing the prospect of gain from ether, he sets his financial hopes on his patented invention of a glass inhaler for administering it. Congress votes him a reward of $100,000, but his patent is infringed and rivals conspire to block justice and rewards. Morton dies young, poor, and unknown.

A beautiful elderly couple are forced to confront Fiona’s (Julie Christie) problems with memory. Always stylish and active, she begins to neglect her appearance and do odd things. She loses her way while cross-country skiing in a familiar terrain; at nightfall, Grant (Gordon Pinsent) finds her frightened and frozen. She decides that she must go into a nursing home, but Grant is horrified to learn that, in order for her to adapt, he may not visit for an entire month. When he finally returns, bearing a bouquet of flowers and hoping for her warm affection, he is stunned to find Fiona pleasant but indifferent to his presence. Instead, she is preoccupied, even infatuated with Aubrey (Michael Murphy), who silently occupies a wheelchair. Fiona is able to interpret Aubrey’s moods and desires.

At first, Grant is hurt and jealous, but gradually he accepts Fiona’s need to be important for someone. Haunted by guilt over an affair with a student years ago, Grant wonders if Fiona is somehow retaliating. When Aubrey’s wife Marian (Olympia Dukakis) brings Aubrey home because she cannot afford the care, Fiona is despondent. He approaches Marian about returning Aubrey to the center. Thrown together by their absent yet present spouses, Marian and Grant indulge in a half-hearted affair. By the time, Aubrey returns, Fiona may have forgotten him, but she still knows Grant and appears to recall his distant infidelity though so much else is lost. But he still loves her and together they can find reasons to laugh.

The movie opens with a shot of a young man stitching up a laceration in his own knee. Another describes how he had to select which of two severed fingers would be re-attached because he could not afford both operations. They are among the millions of Americans without health insurance. But, the narrator says, the movie is not for them; rather it is for the majority of U.S. citizens who do have medical insurance and believe themselves protected.

Through a series of riveting vignettes, for-profit health care is shown to tyrannize the well, ruin the ill, and destroy families. It also erodes the psychological and moral fiber of the people working in the industry. Excursions to England, Canada, France and Cuba are presented in a series of encounters with physicians and patients, none of whom believe that they would be better off in the United States. A French doctor opines that he earns an adequate salary for a good quality of life. Even those seated in a Canadian waiting room profess satisfaction with the care given and understanding about delays. When asked why anyone would accept to pay the expenses of others, an elderly golfer explains patiently that it is what we do for each other in a caring society. Ex-pat Americans gather at a bar to describe their positive experiences with foreign health and maternity care.

Interviews with emotionally distraught people who have worked in the insurance industry reveal the relentless pressure to deny coverage and its reward system that favors those who generate the biggest savings. Special attention is given to Dr. Linda Peeno who testified before Congress in 1996, confessing that she had harmed people for the economic benefit of the insurance industry.

Moore gathers up a group of people whose sorry dilemmas within the U.S. system have left them with serious health problems. He escorts them to Cuba where physicians and nurses are only too pleased to diagnose and treat their illnesses– for free. The movie ends with an exposé of the superior health care given prisoners at Guantanamo and Moore’s stunt at trying to bring the unhappy Americans there for treatment.

The tag line for the documentary short film, Mother Superior, is: "This is your mom. This is your mom on drugs." Methamphetamine addiction has slowly and silently encroached into American suburbia, becoming the drug of choice for women who are struggling to balance the demands of family and career and to meet the expectations of a culture that prizes upbeat, thin, and sexy soccer moms. When the two filmmakers, Alex Mack and Diana Montero, learned that the tidy neighborhoods and wholesome lifestyles of their own hometown, Salt Lake City, ranks third in the United States for meth use among women and that thirty-seven percent of individuals in drug treatment programs are mothers addicted to meth, they set out to make an educational documentary. The twenty-two minute film combines animation, dramatization, information from public health officials and health care professionals, and personal testimony from women in recovery.

Chris Eigemann plays Jake Singer, a well-liked middle-aged English professor to a group of privileged students at a posh high school for precocious young white men with floppy hair styles and ironic disdain, located somewhere in New York City. Having just discovered that his ex-girlfriend is engaged, Singer begins a psychoanalytic treatment with an Argentinian analyst, played with relatively understated gusto by Ian Holm. Singer meets Allegra Marshall (Famke Janssen), a woman whose deceased husband was a benefactor of the school; she is now the single (and rich) mother of two adopted children.

They fall in love, complicated slightly by Singer's father, a curmudgeonly heart surgeon, and a rather strange plot contrivance involving Marshall's failure to tell the adoption agency that her husband had died even though the biological mother had insisted that the child go to a family with a mother and a father. In one other plotline, left satisfyingly unresolved, Singer has clearly been the mentor to a young African American student, who self-sabotages at this otherwise all-white, all-privileged academy.

Jon Voight plays Luke Martin, a Marine sergeant who comes back from Vietnam with both legs paralyzed and faces the many challenges of constructing a liveable life. Jane Fonda is Sally Hyde, the wife of Marine captain Bob Hyde (Bruce Dern), who volunteers at a local vets hospital while her husband is overseas and there meets Luke, whom she had known slightly in high school. Sally gets to understand the plight of disabled vets, and she gets emotionally, and then sexually, involved with Luke.

Bob returns with a minor physical wound, but he has been emotionally traumatized by the war. He agitatedly threatens Luke and Sally with a bayonetted rifle, and Luke leaves Sally to Bob, as he knew he would have to do. Bob is much too distraught to be satisfied with this victory, however, and in a near-final scene, he swims out into the ocean surf to what we understand will be his death.

Manuela (Cecilia Roth) a nurse who works in a transplantation unit, witnesses the accidental death of her romantic son, Esteban, as he chases a car bearing the famous actress, Huma Roja (Marisa Paredes), from whom he wants an autograph. Esteban had longed to know about his absentee father, but his mother had always refused to tell him. His heart is transplanted, and Manuela is shattered by grief, leaves her work, and sets out to recover her past.

Obsessed with her son’s obsessions, Manuela trails the famous actress, Huma, who gives her a job. She finds old friends in the underworld, and a beautiful nun, Rosa (Penélope Cruz), who works with the poor and plans to go abroad. Soon it emerges that Esteban’s father is "Nina," a transvestite prostitute, and that Rosa is not only pregnant by him/her, she has also contracted AIDS.

Rosa’s austere mother was unhappy about her decision to become a religious, but she is even more horrified by her daughter’s pregnancy and illness. Initially reluctant, Manuela nurses Rosa and after her death, she adopts the infant son who is of course named Esteban.

The Cold War. America and Russia (or rather "us" and "them") have both developed miniaturization technology that enables them to reduce objects, including human beings, to microscopic size. The Americans are unable to control the objects’ return to normal size after an hour; the Russians can. An American spy called Benes has stolen this information from the Russians but on his return to America he is injured when the Russians try to kill him. He develops a blood clot in his brain.

To remove the clot, a team of western scientists, led by the surgeon Duval (Edmond O’Brien) and a British vascular specialist, Michaels (Donald Pleasance), is miniaturized inside a submarine which is injected into Benes’s carotid artery. Dr. Duval has a laser gun with which he is to destroy the clot. Also on the submarine are Grant (Stephen Boyd), a military employee in charge of security, and Cora Petersen (Raquel Welsh), Duval’s technical assistant.

The team has an hour to reach the patient’s brain and destroy the clot. They overcome various hurdles, including being washed through an arterial-venous fistula in the jugular vein, having to travel through Benes’s heart (which is temporarily arrested by the outside surgical team to keep the submarine from being crushed), being attacked by antibodies in the lymphatic system, and having to replenish their air supply by breaking through the wall of an alveolar sac.

Finally, they reach the brain and find the clot, but Dr. Michaels turns out to be spying for the other side, and tries to sabotage the mission. He crashes the submarine, but is thwarted by Grant and ingested by a white blood cell. Duval destroys the clot and the crew escapes Benes’s body via the optic nerve. They are washed out in a tear just as they are beginning to return to normal size. Benes is never seen to wake up, but the film’s ending implies that the mission has been successful.

Fifty-something Canadian professor of history and lifelong womanizer Rémy (Rémy Girard) lies in an overcrowded hospital with a fatal illness. Family and friends gather, including Rémy’s estranged son Sébastian (a wealthy financier played by Stéphane Rousseau) from overseas, and Rémy’s ex-wife (Dorothée Berryman) and several previous romantic partners. Rémy and Sébastian fight painfully about Rémy’s philandering, but after a plea from his mother Sébastian decides to make things better for his father, even if they have not been reconciled.

This he does in many ways, most of which involve spending lots of money and many of which are highly irregular or illegal. For example, he arranges to have his father taken into the U.S. for an expensive PET scan that would have required six months’ wait to have free in Canada. And he arranges through Nathalie (Marie-Josée Croze), a childhood friend who is now a heroin addict, to provide a regular supply of heroin to control his father’s pain, which the hospital apparently is not able to do with morphine.

These and other extraordinary measures work for Rémy, and the process of caregiving brings Sébastian and his father closer. (Rémy’s only problem seems to be the feeling that his life has been wasted because he has not left his mark--and he gets help with that, paradoxically, through several conversations with Nathalie.) For his last few days, Rémy and ensemble move to a friend’s lakeside cabin, where the conversation is witty, intellectual, and sexually frank, and the mood upbeat and conciliatory.

In the face of Rémy’s imminent demise, all is forgiven, and others seem to gain insight about their lives. Rémy’s last act is peacefully nodding to a sorrowful Nathalie to begin the series of heroin injections that will end his life. In a final dig at the establishment, the heroin is administered through an IV provided on the sly by a hospital nurse.

In a future society in which biological reproduction is restricted and humanoid robots ("Mechas") are routinely manufactured to supplement the economic and social needs of humans ("Orgas"), Dr. Hobby (William Hurt) creates a prototype child Mecha, David (Haley Joel Osment), who has "neuronal feedback," the ability to love, and "an inner world of metaphor, self-motivated reasoning," imagination, and dreams. David is given to Henry and Monica, a couple whose biological child Martin is incurably ill and cryopreserved, awaiting a future cure.

More specifically, David is created out of Hobby's own loss and given to aid Monica's mourning for Martin, whom she has been unable to "let go" of as dead. It is thus Monica (Frances O'Connor) who must make the decision to perform the "imprint protocol" that will make David love her. After she stops resisting the desire to love a child (of any kind) again and implements the protocol, Martin is unexpectedly cured and comes home.

The ensuing turmoil sends David, accompanied by a robot Teddy bear, out into a nightmare world of adult Mechas, comprised of both Rouge City, where functioning Mechas like Gigolo Joe (Jude Law) do their sex worker jobs and also the fugitive realm where unregistered, discarded Mechas try to find the spare parts they need to rebuild themselves and elude trappers who take them to reactionary "Flesh Fairs" where they are publicly destroyed as an expression of rage against artificial technologies.

Joe and David, both set up and betrayed by humans jealous of their superiority at performing human functions, join together on a quest to make David "real" and return him to Monica. The quest takes them to a partly submerged Manhattan and sends David and Teddy two thousand years into the future to resolve the dystopic narrative.