For families managing life-threatening allergies, access to auto-injectable epinephrine — the medication that reverses the harmful effects of anaphylaxis, is critical.

But the price tag for the go-to prescription, EpiPen, a product manufactured by Pennsylvania-based Mylan, Inc., has skyrocketed in recent years, hitting a record high of $649 for a two-pack. The spike has outraged parents and pediatricians, and in some cases, stunted access for those with no insurance or high-deductible plans.