Summariesfor EPHA5 gene

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related

receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors

in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich

domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity

of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

Alternatively spliced transcript variants encoding different isoforms have been described. (provided by RefSeq,

Aug 2013)

GeneCards Summary for EPHA5 Gene:

EPHA5 (EPH receptor A5) is a protein-coding gene. Diseases associated with EPHA5 include drug psychosis. GO annotations related to this gene include GPI-linked ephrin receptor activity and transmembrane-ephrin receptor activity. An important paralog of this gene is EPHB1.