Abstract

The uptake of ART is increasing worldwide with far reaching changes in clinical practice and available technology since the first IVF birth in 1978. Poorer obstetric and perinatal outcomes following ART compared with spontaneous conception have previously been attributed to multiple pregnancies but there is now also consistent evidence of compromised outcomes for singleton pregnancies. The cause for this is thought to be due both to the underlying subfertility as well as the ART technique. The majority of ART pregnancies will be uncomplicated and this should be emphasized. Discussions regarding possible maternal and perinatal risks should be included in the informed consent process with all couples considering ART.