Abstract: One hundred patients with severe head injury ( Glasgow Coma Scale Score 3 to 8) were studied. Treatment was based on the values of intracranial pressure (I.C.P.). AlI the patients underwent computed tomography scans (C.T.), and continuous I.C.P. monitoring. Patients' data were analyzed on age, sex, APACHE II score, associated lesions, Glasgow Coma Scale Score, C.T. I.C.P. pupillary reaction, as welI as indication of neurosurgical intervention, complications during treatment in the Intensive Care Unit. In this series of severe injuries moto-vehicles accidents were the main cause, unilateral pupillary dilatation was not related to greater mortality or to high intracranial pressure leveI. Neurosurgical intervention was not associated with greater mortality, and focallesion observed in C.T. scarts were related to high intracranial pressure level. Mortality in severe injury is significantly influenced bay low Glasgow Coma Scale Score on admition, associated hypotension, high APACHE II score and high levels of intracranial pressure