Philadelphia Eagles wide receiver DeSean Jackson made a big splash in coach Chip Kelly's first game on the sideline. Bolstered by a dangerous Eagles running game and so-so Redskins secondary, Jackson exploded for seven catches, 104 yards and a touchdown.

Jackson has another friendly matchup in Week 2, along with Chicago's Brandon Marshall and Kansas City's Dwayne Bowe. The dynamic trio ranks among PennLive's top wide receivers in fantasy football this week, while Pittsburgh's Antonio Brown highlights a group of players worth benching.

Here's a quick look at who's up and who's down, as well as the top 40 overall rankings. The stats table below features quick stats on opposing defenses, including passing yardage allowed, touchdowns, total and scoring defense.

THREE UP

Brandon Marshall, CHI, vs. Minnesota: The Vikings struggled to pressure Detroit's Matthew Stafford in Week 1 and allowed 469 total yards in a 34-24 loss. Chicago's offense can find similar success as QB Jay Cutler settles into a rhythm. Marshall is a terrific bet to continue his success against Minnesota after racking up 22 catches for 252 yards in two meetings in '12.

Dwayne Bowe, KC, vs. Dallas: The Giants took to the air in a Week 1 loss to the Cowboys and might have revealed a blueprint for future opponents. While the Chiefs will lean more on the running game, Bowe will be a frequent target against a defense that struggled to keep Victor Cruz and Hakeem Nicks under wraps. With more looks -- he got just six targets in Week 1 -- Bowe's breakout will come in Week 2.

DeSean Jackson, PHI, vs. San Diego: The Eagles present all kinds of problems for opposing defenses, from the run game to Michael Vick to the frantic pace. That chaos proved too much for Washington in Week 1, and the Redskins lost track of Jackson. The same problem is likely for the Chargers, who allowed 346 yards to Matt Schaub in Week 1.

THREE DOWN

Antonio Brown, PIT, at Cincinnati: The Steelers struggled in Week 1 and lost Pro Bowl center Maurkice Pouncey for the season. The interior of Cincinnati's defense is a strength and can collapse the pocket on QB Ben Roethlisberger at any time. Meanwhile, the Bengals are solid in the secondary, fully capable of keeping Brown under wraps in Week 2.

Miles Austin, DAL, at Kansas City: The Chiefs defense was dominant in Week 1, albeit against lowly Jacksonville, and has the look of an underrated unit. Kansas City can pressure and cover, with big bodies up front to defend the run. At Arrowhead Stadium, and with QB Tony Romo nursing sore ribs, it's best to bench Austin and look for other options.

Kenbrell Thompkins, NE, vs. New York Jets: Thompkins got 14 targets from quarterback Tom Brady last week, but reeled in just four of them. New England has a tight turnaround with a Thursday night matchup and is just as likely to lean more on stable veterans Julian Edelman and Danny Amendola (update: Amendola is unllikely to play Thursday night). It's advised to see how Thompkins responds before deploying him in fantasy lineups again.

WAIVER WATCH

Doug Baldwin, SEA, vs. San Francisco: Baldwin, who is two seasons removed from a 51-catch, 788-yard rookie campaign, led the Seahawks with eight targets in Week 1. It's a trend that could continue in Week 2, especially against a 49ers defense that will sell out to stop the Seahawks' ground game.

TOP 40 RANKINGS

A look at our projected top 40 wide receivers for Week 2, which includes opposing defenses and their yardage, touchdowns and points allowed.