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Jane and Joey (Academy Award winners Renee Zellweger and Forest Whitaker) couldn't be more different. She's a take-charge kind of woman who never needs help from anyone, despite being paralyzed from the legs down, and he's a lovable oddball. When Joey convinces Jane to embark on a cross-country road trip, they stumble into one hilarious disaster after another in a heartwarming tale of redemption.