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1 : Mood Disorders Learning Objectives Distinguish between unipolar and bipolar depression, and know the diagnostic criteria for the disorders that fall under each category. Explain how depression affects the whole person, that is, cognitively, emotionally, behaviorally, and physiologically. Discuss how rates of unipolar depression vary as a function of age, gender, and culture, as well as the proposed explanations for these differences. Summarize the evidence for the idea that bipolar disorder is linked to creativity. Summarize the evidence for and against the idea that genetics partially determines who will develop a mood disorder. Discuss the monoamine theory of depression. Discuss the neuroendocrine and neurophysiological abnormalities in depression. Discuss research on the relationship between depression and hormone levels in women. Discuss the behavioral, psychodynamic, learned helplessness, reformulated learned helplessness, cognitive, ruminative response styles, and interpersonal theories of depression. Describe how social values and social status impact the experience of depression. Discuss how tricyclic antidepressants, monoamine oxidase inhibitors, and selective serotonin reuptake inhibitors work, their side effects, and their effectiveness for treating depression. Discuss the type of patient most likely to receive electroconvulsive therapy (ECT), what the therapy entails, and how it might work. Discuss how repetitive transcranial magnetic stimulation (rtms) and vagus nerve stimulation (VNS) work and their effectiveness for treating depression. Explain how light therapy for seasonal affective disorder might work. Discuss drugs used to treat bipolar disorder and their side effects. Symptoms of Depression Cognitive Physiological and Behavioral Emotional Poor, indecisiveness, poor selfesteem,, thoughts, delusions Sleep or disturbances, psychomotor problems, catatonia, fatigue, loss of Sadness, depressed mood, (loss of interest or pleasure in usual activities), 1

2 Number of symptoms Major Depression 5 or more symptoms including sadness or loss of interest or pleasure Dysthymic Disorder or more symptoms including depressed mood Duration At least 2 weeks in duration At least in duration Subtypes of Depression D:\239\9\All About Depression_ Diagnosis_ Overview, DSM-IV.pdf Depression with Melancholic Features Depression with Psychotic Features Depression with Catatonic Features Depression with Atypical Features Depression with Postpartum Onset Depression with Seasonal Patterns Prevalence and Prognosis Among adults, 15-to-24-year olds are likely to have had a major depressive episode in the past month. Depression is common among children than among adults. Depression may be most likely to leave psychological and social scars if it occurs initially during childhood, rather than during adulthood. Age Differences in Depression 2

3 Prevalence: Culture? Incidence of depression may be increasing (multicultural data: young more likely to have had an episode of depression) Incidence of depression is higher in economically cultures Prevalence: Culture? Nesse in Buss "If I had to put my position in a nutshell, I'd say that mood exists to regulate, so that we spend more time on things that work, and less time on things that don't. Randolph Nesse in NY Times People have larger goals today than prior to WWII Depression is associated with disengaging from goals (Klinger) Prevalence: Culture? So, is there a connection between depression; goals, & our culture? If so, how would that influence treatment decisions? Gender Differences in Depression Women more vulnerable. Why? lower sense of over important areas of life, more chronic, and more What does this suggest about treating women s depression? Seasonal Affective Disorder Causes are unclear Could be related to seasonal changes in rhythms treatment is effective Bipolar Disorder Bipolar I Disorder - Features - DSM IV Criteria.pdf Bipolar I Disorder - DSM IV Criteria.pdf What are the differences between Bipolar I & II? Major Depressive Episode ( ) Mania ( ) Hypomania ( ) 3

6 Social Perspectives On Mood Disorders The cohort effect: too many changes, too high of expectations (p.328, Fig. 9.6) Social status: less status, more depression. Minority groups/women Cross-cultural differences: less depression in non-industrialized cultures; or depression may be more somatic Biological Treatments for Mood Disorders Medication Electroconvulsive therapy (ECT) Repetitive transcranial magnetic stimulation Vagus nerve stimulation Light therapy Exercise Psychological Treatments for Depression Behavioral Therapy Increase positive reinforcers and decrease aversive events by teaching the person new skills for managing interpersonal situations and the environment Cognitive-Behavioral Therapy Challenge distorted thinking and help the person learn more adaptive ways of thinking and new behavioral skills Psychodynamic Therapy Help the person gain insight to unconscious hostility and fears of abandonment to facilitate change in self-concept and behaviors 6

7 Handout 9.1: Cognitive Distortions Among Students Group 1: All-Or-Nothing Thinking distortion defined as seeing things in black and white, all-or-nothing terms, not realizing that there are different degrees of everything. Group 2: Overgeneralization distortion defined as seeing a single negative event as part of a large pattern of negative events. Group 3: Mental Filter Your task is to develop a brief skit that illustrates cognitive distortion defined as focusing only on the negative aspects of a situation, ignoring the positive aspects. 7

8 Group 4: Disqualifying the Positive distortion defined as rejecting positive experiences by discounting them. Group 5: Jumping to Conclusions distortion defined as concluding that something negative will happen or is happening with no evidence. Think of a situation that has actually happened or could happen to a college student, where the student shows the above thinking error. As part of your skit, demonstrate how you would react to someone who shows this kind of thinking error. How would you try to get them to be more Group 6: Emotional Reasoning distortion defined as assuming that negative emotions necessarily reflect reality. Think of a situation that has actually happened or could happen to a college student, where the student shows the above thinking error. As part of your skit, demonstrate how you would react to someone who shows this kind of thinking error. How would you try to get them to be more 8

9 Group 7: Personalization distortion defined as attributing negative events to the self when they really have nothing to do with oneself. 9

Chapter 6 Mood Disorders Bipolar Disorder Class Objectives What is Bipolar Disorder? How does this differ from Unipolar Mood Disorder? How do Mood Disorders develop? How are Mood Disorders treated? What

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Treatments for Major Depression Drug Treatments The two (2) classes of drugs that are typical antidepressants are: 1. 2. These 2 classes of drugs increase the amount of monoamine neurotransmitters through

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MOOD DISORDERS AND SUICIDE I. Understanding and Defining Mood Disorders A. The disorders described in this chapter used to be called "depressive disorders," "affective disorders," "depressive neuroses."

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What is depression? More than just feelings of unhappiness, clinical or major depression is a mood disorder a medical illness that involves both the body and mind. 1,2 The difference between clinical depression

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