1

They all can:
Amitriptyline and Pregabalin are medications that come from classes of medications that can be used to treat depression and mood disorders as well as pain. I would put more emphasis on these rather than the methadone. All in combination can be your issue.
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Methadone is a synthetic opiate used for pain control and in the rehabilitation of opiate addicts. Methadone used in rehabilitation relieves craving, suppresses withdrawal symptoms, and blocks the euphoric effects associated with opiates such as heroin.
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3

I've asked a lot:
Of MD's this question. Some start you off on the new med right after stopping the old one. Some wait as much as two weeks. You are mixing an herb with a Tricyclic, so I'd play it safe and wait awhile. As a psychiatrist who knows about herbs. Most don't.
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5

Odds are:
You'll likely be gone as overall this isn't a particularly high dose. You may notice some sedation, nausea, itching or constipation. But the bigger issue is changing how you take a medication, particularly opioids, without reviewing this with your doctor. It's incredibly important to discuss medication changes with your doc. Not doing so could lead to your doc no longer prescribing for you.
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8

Please tell us:
How many mg are in the 20 cc or mls of Methadone and then I can tell you what the conversion is. Please resubmit the question. Thanks. Methadone in the states comes in different strengths per cc.
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12

Methadone:
The best and safest way is to do a gradual dose reduction every 2 weeks (although you will read and see shorter times like 3-4 days). This can continue until the dose is so low that it can be discontinued.
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16

Sometimes:
It can definitely aid in sleeping as it has significant drowsy side effects, but is usually prescribed to help with another condition like chronic fibromyalgia pain or other neurological pain like migraines sometimes with the added benefit of also helping you sleep. I'm sure there are some doctors out there who may prescribe it for the sole purpose of being a sleep aid.
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17

Useful medication.:
Amitriptyline can be helpful for many medical conditions, including migraines, insomnia, and depression. Side effects such as sleepiness, dry eyes, dry mouth, and constipation may occur. Side effects tend to be less if the medication is started at a low dose and gradually increased (titrated).
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18

Elavil (amitriptyline):
Can be weened over a period of a few weeks at this dose. Be sure to discuss this with your prescribing doctor. If you have it in tablet form you can break it into quarters and take away one quarter every 5 days. Consider replacing it with Pamelor (nortriptyline) which is less anticholinergic (dry mouth blurred vision etc)
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19

Ami side effects:
Not unusual but can be circumvented by using the lowest effective dose - 2.5 - 10 mg. The dose is individualised based on med sensitiviy, family history of success (and the effective dosage), type of illness being treated, comorbid medical and emotional disease, anticipated side effects and potential/ currently existing interactions with other medications/supplements.
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20

Yes,:
It is contraindicated to attempt to come off it during pregnancy because lowering the dose or withdrawal can lead to a spontaneous loss of the baby. Pregnant women have been treated with Methadone for more than 25 years and neither Methadone or other opiates have not been shown to directly cause birth defects. Methadoneandpregnancy. Com.
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27

See below:
Call your doctor at once if you have any of these serious side effects: •shallow breathing; •hallucinations or confusion; •chest pain, dizziness, fainting, fast or pounding heartbeat; or •trouble breathing, feeling light-headed, or fainting.

29

Not good or bad:
Methadone saves some people's lives (particularly those who are opioid dependent) and if used improperly can be lethal. A medication is neither good or bad but rather it depends upon the context in which it is used.
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