Etymologies

Middle English noiesom : noie, harm (short for anoi, annoyance, from Old French, from anoier, to annoy; see annoy) + -som, adj. suff.; see -some1.

(American Heritage® Dictionary of the English Language, Fourth Edition)

From Middle English noy (short for annoy, from an(n)oien, enoien from Anglo-Norman anuier, from Old French enuier (French: ennuyer), from Late Latin inodiare (to make hateful), from in- (intensive prefix) + odium (hate). (Wiktionary)

The floor of the cellar was a kind of noisome cesspool: one slipped on the greasy mud -- floundered about in it: for all that, this cellar was almost entirely filled with cases of all kinds, with queer-looking bundles, with objects of various shapes and sizes.

With friends like the IRA and a disciplinary system that includes throwing snakes and tarantulas into the beds of women hostages, including Mlle Betancourt, who dared to try to escape, Farc represents the kind of noisome infestation that public benefactors such as General Pinochet used to sanitise so effectively.

Hold on tight: But what could the Concord sage have known of the news off the boat when that boat was a keelboat or a broadhorn docking at the noisome slum of Natchez-under-the-Hill or New Orleans where some eighty years later a precocious Jelly Roll Morton was learning the street songs that would ultimately scorch the stately décor of the Library of Congress's Coolidge Chamber Music Auditorium when he recorded them for Alan Lomax?

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"COMINIUS: I offer'd to awaken his regardFor's private friends: his answer to me was,He could not stay to pick them in a pileOf noisome musty chaff..."- William Shakespeare, 'The Tragedy of Coriolanus'.