Dupuytren’s Disease

In Dupuytren’s disease, the tough connective tissue within one’s hand becomes abnormally thick which can cause the fingers to curl and can result in impaired function of the fingers, especially the small and ring fingers. It usually has a gradual onset, often beginning as a tender lump in the palm. Over time, pain associated with the condition tends to go away, but tough bands of tissue may develop. These bands, which are the source of the reduced mobility commonly associated with the condition, are visible on the surface of the palm and may appear similar to a small callus. It commonly develops in both hands and has no connection to dominant or non-dominant hands, nor any correlation with right- or left-handedness.

The contracture sets in slowly, especially in women. However, when present in both hands and when there is associated foot involvement, it tends to progress more rapidly.

The condition may require surgical treatment if it progresses such that you are unable to put your hand flat on a tabletop. A non-surgical injection treatment is often successful, particularly if the PIP joint is not involved. Xiaflex® may be an option for you. Please study the IMPORTANT SAFETY INFORMATION regarding this injection treatment.