Businesses like CVS Health, Coca-Cola Co. and Comcast Corp. are also re-evaluating how to reach customers and deliver products while the pope is in town.

But businesses aren't the only ones paying big bucks for the six-day visit. Security comes with a major price ticket. According to The Washington Post, the federal government forks over $4.5 million a year to handle National Special Security Events like this one. But it's unlikely that amount will cover all costs associated with keeping the pope and his admirers safe.

The largest crowds are expected in Philadelphia; some say more than 1 million people will travel to see the pope. City officials say the two-day visit will cost Philly more than $12 million. (Video via Visit Philadelphia)

Ten thousand folding chairs, 10,000 feet of fencing, 3,300 porta-potties and the manpower to put it all up and take it all down isn't cheap. (Video via KYW)