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Advances in statistical methods for genetic improvement of livestock. Edited by D. Gianola and K. Hammond. Advances Series in Agricultural Sciences Table of contents

Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice. Molecular consequences of animal breeding. Durkin, K. Serial translocations by means of circular intermediates underlies color sidedness in cattle. Nature , 81—84 This study identified a novel CNV-generating mechanism that may underlie exon shuffling by studying coat-colour variation in cattle. Clop, A. A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep. This paper describes one of the most convincing examples in mammals of a phenotype resulting from perturbed microRNA-mediated gene regulation.

Georges, M. This paper reviews the current molecular understanding of the unique phenomenon of polar overdominance at the ovine callipyge locus. MacArthur, D. A systematic survey of loss-of-function variants in human protein-coding genes. Bittles, A. The costs of human inbreeding and their implications for variations at the DNA level.

Frequency of mosaicism points towards mutation-prone early cleavage cell divisions. VanRaden, P. Harmful recessive effects on fertility detected by absence of homozygous haplotypes. Dairy Sci. This study is one of the first demonstrations of how the availability of genome-wide SNP genotypes for large populations can be used to effectively identify haplotypes harbouring EL mutations affecting fertility.

Adams, H. Identification of a nonsense mutation in APAF1 that is likely causal for a decrease in reproductive efficiency in Holstein dairy cattle. A Kb deletion with antagonistic effects on fertility and milk production segregates at high frequency in Nordic Red cattle: additional evidence for the common occurrence of balancing selection in livestock.

Advances in Statistical Methods for Genetic Improvement of Livestock eBook

Israeli And Palestinian Narratives of Conflict: Historys Double Helix (Indiana Series in Middle East Studies).

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Sourcebook of parallel computing.

Estimation of coancestry in Iberian pigs using molecular markers. Garant, D. How to use molecular marker data to measure evolutionary parameters in wild populations. Aguilar, I. A unified approach to utilize phenotypic, full pedigree, and genomic information for genetic evaluation of Holstein final score.

This study is one of the first demonstrations that pedigree, genomic and phenotypic information from millions of animals could be combined in a single-step approach to predict GEBVs.

Advances in statistical methods for genetic improvement of livestock.

An equivalent gametic model for animal dominance genetic linear model

A class of Bayesian methods to combine large numbers of genotyped and non-genotyped animals for whole-genome analyses. Computational strategies for alternative single-step Bayesian regression models with large numbers of genotyped and non-genotyped animals.

Misztal, I.

Invited review: efficient computation strategies in genomic selection. Animal 11 , — Changes in genetic selection differentials and generation intervals in US Holstein dairy cattle as a result of genomic selection. Natl Acad. USA , — This study demonstrates the impact of GS on genetic gain in the US dairy industry.

The value of using DNA markers for beef bull selection in the seedstock sector. Lourenco, D. Genetic evaluation using single-step genomic best linear unbiased predictor in American Angus. Abell, C. Total cost estimation for implementing genome-enabled selection in a multi-level swine production system.