My upper legs itch most of the time. It is worse at night or when I have tighter pants on. I have no rash, no bumps or any other sign that something is wrong. The itch feels like it's deep under the skin and it also feels like I have a slight burning feeling. When I scratch my legs it hurts. It is painful enough that I don't like scratching. It feels like the pain is deep in my muscles. I end up with bruises from scratching...this is only on my thighs. Can anyone give me some insight as to what might be wrong?

I'm wondering if it's an allergic reaction either to a drug you're taking or contact dermatitis? Are you taking narcotic pain pills? Antibiotics? I had the same reaction when I took sulfa drugs for a UTI. Have you switched laundry detergent, started using dryer sheets, or been using a new body lotion or bath soap? Any of these are possibilities. If not that, I can't even imagine unless it's something you're eating. Good luck discovering what it could possibly be!
Soibhan