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Adrenal and Puberty Center

The Adrenal and Puberty Center at The Children’s Hospital of Philadelphia provides streamlined, coordinated care for children and adolescents with adrenal disorders and conditions that may affect puberty and gonadal function.

Congenital Adrenal Hyperplasia

Congenital adrenal hyperplasia (CAH) is an inherited disorder of the adrenal glands that can affect both boys and girls. People with CAH cannot properly make some hormones that are essential to maintain life. At the same time they produce too much of male type of hormones, called androgens. These hormone imbalances can lead to serious illness, early puberty, growth concerns and other problems.

Why Choose Us?

A benefit of choosing CHOP for treatment of adrenal and puberty disorders is the access your child will have to a specialized team of healthcare providers who can address his or her needs throughout childhood.

Our Team

We bring together a multidisciplinary team of endocrinologists, urologists, nurse practitioners, social workers, psychologists, genetic counselors and other professionals with experience in treating adrenal disorders and conditions that affect sexual development.

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Klinefelter Syndrome

Klinefelter syndrome is a chromosomal anomaly that affects males. It occurs when a boy is born with an extra X chromosome. Klinefelter syndrome affects 1 in 500-1,000 newborn males, making it is one of the most common chromosomal disorders.