An oxidative Strecker reaction of aldehydes, amines, and TMSCN in a biphasic
solvent system in the presence of Oxone, TBAB and sodium bicarbonate affords
α-iminonitriles in good yields. This three component reaction is applicable to a
wide range of aldehydes and amines.
J.-B. Gualtierotti, X. Schumacher, Q. Wang, J. Zhu, Synthesis, 2013, 45,
1380-1386.