ZOLOFT and other antidepressant medicines may increase suicidal thoughts or actions in some people 24 years of age and youngerespecially within the first few months of treatment or when the dose is changedDepression or other serious mental illnesses are the most important causes of suicidal thoughts or actionsWatch for these changes and call your healthcare provider right away if you notice new or sudden changes in moodbehavioractionsthoughtsor feelingsespecially if severePay particular attention to such changes when ZOLOFT is started or when the dose is changedKeep all follow-up visits with your healthcare provider and call between visits if you are worried about symptoms.

Takingor within 14 days of stoppingMAOIsincluding the MAOIs linezolid and intravenous methylene bluebecause of an increased risk of serotonin syndromeSee WARNINGS AND PRECAUTIONSDRUG INTERACTIONSTaking pimozideSee DRUG INTERACTIONSWith known hypersensitivity to sertralinee.ganaphylaxisangioedemaSee ADVERSE REACTIONS

No overall differences in safety or effectiveness were observed between these subjects and younger subjectsand other reported clinical experience has not identified differences in responses between the elderly and younger patientsIn generaldose selection for an elderly patient should be conservativeusually starting at the low end of the dosing rangereflecting the greater frequency of decreased hepaticrenalor cardiac functionand of concomitant disease or other drug therapy.

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