Background and Aim: Low back pain (LBP) is one of the common disorders that causes impairment of daily activities of the Person. Ever various methods have been used in the treatment, but in the case of a comprehensive treatment, researchers generally have not achieved consensus. Hence aim of this study was to compare the effect of two treatment methods Kinesio Taping and sole reflexology on the pain severity and disability of patients with chronic nonspecific low back pain. Materials and Methods: In this semi-experimental experiment 30 male patients with chronic nonspecific low back pain aged 20-40 years were randomly divided into three groups of Kinesio Taping (n=10), sole reflexology (n=10) and control group (n=10). The treatment period lasted 6 weeks and each week consisted of 3 sessions. Place paste Kinesio taping start below the hip bone And then continued the paraspinal muscles And on how to reflexology the spine point on the foot massage was given by massage techniques. In order to assess the pain severity and disability, the VAS and Oswestry Questionnaires were used respectively before and after the treatment. For data analysis, paired t-test and ANOVA was applied at the significance level of P≤0.05. Results: Comparison within and between groups showed an effectiveness of both methods Kinesio taping and foot reflexology on pain and disability (p=0.001). Comparing results of Tukey test Group Kinesio taping significantly better pain relief than the reflexology group showed after intervention (p=0.001) But the amount of disability in people Kinesio taping and reflexology thousand, a difference was observed between the two groups (p= 0.93). Conclusion: Kinesio Taping and sole reflexology can be effective in reducing pain and disability in patients with nonspecific chronic low back pain, but Kinesio Taping greater pain reduction in patients towards sole reflexology.