Summary Objective. Indirect self-destructiveness and its manifestations in homosexual individuals remains a poorly studied area. Aim. The aim of this study was to comprehensively examine the syndrome of indirect self-destructiveness in homosexual individuals. Material and method. 156 homosexual individuals (111 males, 45 females) aged 25-35 (mean age of 29.6) and 561 heterosexual individuals (400 males, 161 females) aged 24-36 (mean age of 28.2) were studied with regard to indirect self-destructiveness. The research instrument was the Polish version of the Chronic Self-Destructiveness Scale (CS-DS) including: Transgression and Risk (A1), Poor Health Maintenance (A2), Personal and Social Neglects (A3), Lack of Planfulness (A4) and Helplessness and Passiveness in the face of problems (A5). Results. Homosexual individuals obtained significantly higher scores than heterosexual ones in numerous scales: Indirect Self-Destructiveness – global (general) index (p<0.001), A1-Transgression and Risk (p<0.001), A4-Lack of Planfulness (p<0.001) and A5-Helplessness, Passiveness (p=0.04) There were no significant differences in the Poor Health Maintenance scale (A2). They also achieved significantly higher scores in the subscales assessing using of psychoactive substances. Factor analysis revealed the presence of only one factor both in the group of homosexual and heterosexual individuals. Conclusions. The research results indicate that, as compared with the group of hetero sexual individuals, in the group of homosexuals there occurs a worsening in psychological functioning, which may be also manifested by an increased indirect self-destructiveness index. The increased intensity of indirect self-destructiveness in homosexual individuals may be considered a manifestation of worsened psychological functioning. The homosexual individuals look after their health similarly to heterosexuals.