In his new book (Ageless Face, Ageless Mind October 2007) , Dr. Perricone announces a new form of carnosine that actually breaks AGEs. He even states that he is the first one to announce it, even before the Life Extension Foundation. It is not available on his site yet however. When I called I was told that they don't know when some of the new items listed in his book will be available. Does anyone have any infomation on this "new" type of carnosine? (Great book by the way.)

Google has some on-line links to mCAR carnosine athttp://www.google.com/search?hl=en&q=mCAR+carnosine&btnG=Google+Search ."Dr. Perricone has a new book out called "Ageless Face, Ageless Mind" that I just read the other night. The book focuses on the damaging effects of glycation on the skin and the body and ways to combat the production and effects of AGEs (advanced glycation endproducts). He has an entire chapter on L-carnosine, but the type of carnosine he is focusing on is a new carnosine product (called mCar) that is supposed to actually increase carnosine levels in the body when taking internally, since it is not broken down into it's constituent amino acids in the gut, as L-carnosine is." - from http://www.smartskincare.com/forum/viewtopic.php?p=12925 . See alsohttp://books.google.com/books?um=1&q=Ageless+Face%2C+Ageless+Mind&btnG=Search+Books .Incidentally, supplemental beta-alanine combines with excess histidine in muscles to produce carnosine there, which has the effect of raising low acidic pH back to the normal range around 7. I have wondered if carnosine's impact on pH might be connected with suppression of the cytoskeleton in senescent cells. The favorable impact of carnosine on increasing the number of cell divisions availableprior to senescence is usually attributed to its antioxidant and antiglycating properties in relation to DNA defense. Telomeric DNA, not being repaired during transcription like an active gene, needs solid antioxidant defense to yield the maximum number of cell divisions.

Well, the new carnosine wasn't the Mcar. It's now been a year since Dr. Perricone published that book and announced the new age breaker mcar. There is no sign anywhere online or on the Perricone site of this highly anticipated product. If anyone ever sees it, let us know. If it's being patented or going through an FDA testing process it will be years, if ever, before we have access to mcar. I guess that dancer in the book is the only one that gets to erase her wrinkles with mcar.....

Meat is the main dietary source of carnosine. High doses of carnosine are necessary for therapeutic effect because the body naturally degrades carnosine with the enzyme carnosinase. Carnosine is not only effective in prevention, but it is also active after free radicals react to form other dangerous compounds, like lipid peroxides and and secondary products. So, New Form Of Carnosine that breaks AGEs.-----------------------------------------------samflutchDrug Detox

Since Dr. Perricone's book came out he's been getting questions on his website on how to get the wonderful Mcar. He recomends buying carnosine from lef.org. It appears that the age breaking mcar is still not available, likely because it's patent pending. Here is the patent application for MCAR http://www.freepatentsonline.com/y2008/0027212.html