Determinants of Medical and Surgical Treatment Outcomes in Chronic Sinusitis

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ClinicalTrials.gov Identifier: NCT01332136

Recruitment Status
:
Completed

First Posted
: April 8, 2011

Last Update Posted
: March 29, 2016

Sponsor:

Oregon Health and Science University

Collaborator:

National Institute on Deafness and Other Communication Disorders (NIDCD)

Determinants of Medical and Surgical Treatment Outcomes in Chronic Sinusitis

Official Title

Determinants of Medical and Surgical Treatment Outcomes in Chronic Sinusitis

Brief Summary

This research study will be completed by enrolling a prospective, observational cohort study to evaluate medical versus surgical treatment outcomes for chronic sinus disease. This investigation will compare quality of life outcomes between each treatment type, as well as measure cellular and molecular markers of inflammation in the sinus mucosa, to create models that predict improvement in quality of life following treatment.

Detailed Description

Not Provided

Study Type

Observational

Study Design

Observational Model: CohortTime Perspective: Prospective

Target Follow-Up Duration

Not Provided

Biospecimen

Retention: Samples Without DNA

Description:

Sinonasal mucosal tissue specimens

Sampling Method

Non-Probability Sample

Study Population

Adult patients who have failed intial medical management for chronic sinusitis and have presented to a tertiary care clinic for continued treatment.