The presence of multiple renal arteries per kidney is associated with
hypertension. The smaller vessel diameter is thought to lead to decreased renal
perfusion, which activates the renin-angiotensin-aldosterone system (RAAS),
resulting in increased systemic blood pressure. We measured renal blood flow
(RBF) using dynamic contrast enhanced (DCE) MRI to investigate the relation
between number of renal arteries, RAAS activity and RBF. The number of renal
arteries was associated with reduced RBF and increased RAAS activity. In all
patients, we observed that reduced RBF was associated with increased RAAS
activity.

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