On mythic difficulty you'll want to make sure you have Soul Shards ready to Chaosblitz the Screaming Shrike's (the bats), if these do not die in time they will eject the person inside the pod.

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Make sure you cast Verbrennen on the target that will make you hit the highest amount of targets since you'll be playing Feuer und Schwefel. This way you will gain more Soul Shards, also the imps have to die before they cast.

The reason i suggest you play Schattenfuror on this fight is to stun the imps on the platform. Also, this means you should play Sephuz' Geheimnis since you will reliably be able to proc this off cooldown.

Since a lot of the pacs on this fight contain 5-6+ mobs you'll also want to consider playing Alythess' Pyrogenik as you will be casting Feuerregen quite a lot.

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I suggest using Sephuz' Geheimnis because you will be able to use your imps Magie ausbrennen to dispell Schlafkanister from people in your raid. Be careful with this as you want to make sure nobody is standing within 10 yards of the person you're dispelling.

Position yourself atleast 10 yards away from everyone else so you dont risk being slept by someone else.

You may want to place a Dämonisches Tor going onto the bridge. This will allows your tanks to take it and clear whatever might be on the bridge. This depends on the tactic you're using.

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Save your Seelenernte for the Apokalypseprotokoll intermission and pop all your cooldowns on the adds. They take increased damage that decreases throughout the phase until the cast is done.

You can place a Dämonisches Tor going from one platform to another, this will allow people to get from platform to platform faster. Be careful with this as you might hit a Diabolische Bombe while traveling in the gateway.

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You can use your Dämonischer Zirkel to get back into the group after running out with Nekrotischer Griff. This is mainly only doable on Heroic as your mythic tactic may not allow you to do this.

You can cast Verbannen on the Funke von Taeshalach to stop it from moving. This also makes it unable to take damage so it can be very useful. You can break this cc by casting Verbannen once again.

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On Normal and Heroic make sure you have cooldowns ready 30 seconds after Argus reaches 40%. This means you'll have cooldowns for Konstellareinheit.

During this phase you should mainly target the add taking increased fire damage since your Verbrennen, Feuersbrunst and Feuerbrand are all fire damage. Then use Verwüstung onto any of the other adds and cast as many Chaosblitz during that time as possible. This is Chaos damage and will deal increased damage to any of the adds.

During the final phase you'll want to make sure to save Soul Shards to focus the Neuerschaffungsmodul. These are going to be very high priority as they're casting Neuerschaffungsimpuls and if this finishes casting you will most likely wipe.

Try your best to utilize Dämonischer Zirkel when he casts Höllisches Brennen, try to place your portal behind the pillars he spawns. This will allow you to portal into safety rather than spending time running to safety.

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Do your best to cast Verwüstung when there is 10+ seconds until Atrigan casts Knochensäge and Belac casts Teufelsböe. This way you will avoid gaining unnecessary torment.

Place your Dämonischer Zirkel off to the side so you can either portal out when Atrigan casts Verknöcherte Stacheln on you, or if you find yourself inside a Verknöcherte Stacheln circle (the big purple domes). This will overall help your raid and reduce the amount of torment you will gain from these mechanics

You do not gain torment from having an Immolate on a target that's casting. This means you should ideally refresh Immolate when there's 2-3 seconds until a boss is casting.

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Do your best to cast your Incinerates on the target where you will be able to hit the highest amount of targets when cleaving. This way you will generate more shards and overall do more damage. Also the adds have to die on this fight so the faster you kill them the better.

Place your Dämonischer Zirkel off to the side so you can teleport out when the boss starts to draw in the pools.

When there are 3+ targets up you should cast Rain of Fire instead of Chaos Bolt. If you have Havoc available this goes up to 4 targets. Keep in mind that this means all targets are inside the radius of your Rain of Fire for its full duration.

This one is a bit more tricky, depending on what difficulty you're up against i would choose between 2 different talent setups. The first setup is as follows:

Normal and Heroic:

This talent setup is the standard single target spec for Destruction. The reason you'll want to choose this spec for Normal and Heroic is that adds will most likely die very fast where damage on high-health targets are higher priority. Therefore this is my recommended build.

Mythic:

This talent setup is the standard multi-target AoE spec for Destruction. On Mythic there are more adds and that's the reason this spec pulls ahead on Mythic difficulty. If your raid has a very high add damage and are lacking boss damage you may want to consider switching back to the standard single target spec.

General tips:

The only real tip i have for this fight is to utilize your cooldowns such as Havoc to the best of your ability. There are a lot of targets on this fight and by playing it smart you should be able to pull some decent numbers.

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When the boss casts Rückstoß she will summon a bunch of fel and light orbs. Once stood in one of those orbs (of the same source as your debuff) you will gain a stacking damage increase. Try to align your second/third set of cooldowns with this debuff.

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On Fallen Avatar there are 2 bosses in the first phase. However, since you may end up pushing into the final phase too quickly it's not always beneficial to the raid to cleave. Therefore you should choose Channel Demonfire rather than Wreak Havoc.

You should do your best at having 4+ soul shards ready for when the Maiden of Valor is casting her Säuberungsprotokoll, at this point you should Havoc the Fallen Avatar and damage the Maiden until she stops casting. When she is done casting you should not damage her until the next time she is casting.