Formerly one sought the feeling of the grandeur of man by pointing to his divine origin: this has now become a forbidden way, for at its portal stands the ape, together with other gruesome beasts, grinning knowingly as if to say: no further in this direction! One therefore now tries the opposite direction: the way mankind is going shall serve as proof of his grandeur and kinship with God. Alas this, too, is vain! At the end of this way stands the funeral urn of the last man and gravedigger (with the inscription 'nihil humani a me alienum puto'). However high mankind may have evolved—and perhaps at the end it will stand even lower than at the beginning!— it cannot pass over into a higher order, as little as the ant and the earwig can at the end of its 'earthly course' rise up to kinship with God and eternal life. The becoming drags the has-been along behind it: why should an exception to this eternal spectacle be made on behalf of some little star or for any little species upon it! Away with such sentimentalities!

It is a right, yes a duty, to search in cautious manner for the numbers, sizes, and weights, the norms for everything [God] has created. For He himself has let man take part in the knowledge of these things ... For these secrets are not of the kind whose research should be forbidden; rather they are set before our eyes like a mirror so that by examining them we observe to some extent the goodness and wisdom of the Creator.

It is certain that as a nation we are all smoking a great deal too much ... Smoking among boysto whom it cannot possibly do any kind of good, while it may do a vast amount of active harmis becoming prevalent to a most pernicious extent. ... It would be an excellent thing for the morality of the people could the use of intoxicants and tobacco be forbidden to all persons under twenty years of age. (1878)

In London Daily Telegraph (22 Jan 1878). Reprinted in English Anti-Tobacco Society and Anti-Narcotic League, Monthly letters of the Committee of the English Anti-Tobacco Society and Anti-Narcotic League 1878, 1879, 1880, (1 Feb 1878), 85.

The scientific method is a potentiation of common sense, exercised with a specially firm determination not to persist in error if any exertion of hand or mind can deliver us from it. Like other exploratory processes, it can be resolved into a dialogue between fact and fancy, the actual and the possible; between what could be true and what is in fact the case. The purpose of scientific enquiry is not to compile an inventory of factual information, nor to build up a totalitarian world picture of Natural Laws in which every event that is not compulsory is forbidden. We should think of it rather as a logically articulated structure of justifiable beliefs about nature. It begins as a story about a Possible World—a story which we invent and criticise and modify as we go along, so that it ends by being, as nearly as we can make it, a story about real life.

The unprecedented identification of the spectrum of an apparently stellar object in terms of a large red-shift suggests either of the two following explanations.The stellar object is a star with a large gravitational red-shift. Its radius would then be of the order of 10km. Preliminary considerations show that it would be extremely difficult, if not impossible, to account for the occurrence of permitted lines and a forbidden line with the same red-shift, and with widths of only 1 or 2 per cent of the wavelength.The stellar object is the nuclear region of a galaxy with a cosmological red-shift of 0.158, corresponding to an apparent velocity of 47,400 km/sec. The distance would be around 500 megaparsecs, and the diameter of the nuclear region would have to be less than 1 kiloparsec. This nuclear region would be about 100 times brighter optically than the luminous galaxies which have been identified with radio sources thus far. If the optical jet and component A of the radio source are associated with the galaxy, they would be at a distance of 50 kiloparsecs implying a time-scale in excess of 105 years. The total energy radiated in the optical range at constant luminosity would be of the order of 1059 ergs.Only the detection of irrefutable proper motion or parallax would definitively establish 3C 273 as an object within our Galaxy. At the present time, however, the explanation in terms of an extragalactic origin seems more direct and less objectionable.

There are many things akin to highest deity that are still obscure. Some may be too subtle for our powers of comprehension, others imperceptible to us because such exalted majesty conceals itself in the holiest part of its sanctuary, forbidding access to any power save that of the spirit. How many heavenly bodies revolve unseen by human eye!

In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion.
(1987) -- Carl Sagan