Mr Keogh, 51, said: “When I go to bed at night my last thought is of my daughter. When I wake up in the morning, the first thought is of my daughter.”

Mrs Hopwood, 49, also told the press conference: “I walked the streets looking for Donna and asked her friends.

“We did what we had to do and tried everything.

“It’s been devastating, absolutely devastating for all the family.”

However, police today confirmed that the appeal had not shed any new light on the case.

A Cleveland Police spokeswoman said: “There has been no further developments, however, the investigation into Donna’s disappearance continues.”

Detective Chief Superintendent Mark Braithwaite, Cleveland Police head of crime and operations, offered a personal hotline last month to try to encourage anyone who could help the investigation to come forward.

He said: “This family have endured nine years of agony not knowing what happened to their daughter and it’s time that agony was ended.

“Someone knows something and I’m hoping over the years that attitudes have changed and people have matured.”