Lena Dunham's new show makes growing up painfully funny

"There is something a little bit ironic about calling 24-year-old women 'girls,'" Dunham says. "But at the same time, I don't think they would self-identify as 'women.'"

The last time Lena Dunham was at the South by Southwest film festival, at age 23, plugging a (literally) homemade indie film with flyers from Kinko's, she did a sit-down with the New York Times in which she mentioned, among other things, that she was a macrobiotic vegan. Two years later, we're in the same hotel caf, and Dunham is here with HBO, which has commandeered seemingly every surface in town to promote her new comedy series, Girls (premiering April 15 at 10:30 p.m. ET). She orders a hamburger, medium rare.