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Drinking coffee daily was associated with a lower risk of deaths from Type 2 diabetes, cardiovascular diseases, and neurological diseases in nonsmokers.

Regular consumption of coffee can be included as part of a healthy, balanced diet.

Embargoed until 3 p.m. CT/4 p.m. ET Monday, Nov. 16, 2015

(NewMediaWire) - November 16, 2015 - DALLAS, Texas - Drinking a second or third cup of coffee may do more than get you through a long day — it may also reduce your risk of death from heart disease and other illnesses.

In a study reported in the American Heart Association journal Circulation, people who regularly drank moderate amounts of coffee daily —less than 5 cups per day — experienced a lower risk of deaths from cardiovascular disease, neurological diseases, Type 2 diabetes and suicide.

The benefit held true for drinking caffeinated and decaffeinated coffee, suggesting it’s not just the caffeine providing health perks but possibly the naturally occurring chemical compounds in the coffee beans.

“Bioactive compounds in coffee reduce insulin resistance and systematic inflammation,” said Ming Ding, M.D., the study’s first author and doctoral student at the Harvard T.H. Chan School of Public Health in Boston, Massachusetts. “They might be responsible for the inverse association between coffee and mortality. However, more studies are needed to investigate the biological mechanisms producing these effects.”

The findings are based on data from three large ongoing studies: 74,890 women in the Nurses’ Health Study; 93,054 women in the Nurses’ Health Study 2; and 40,557 men in the Health Professionals Follow-up Study.

Researchers assessed coffee drinking every four years using validated food questionnaires and followed participants for up to 30 years. During the follow-up period, 19,524 women and 12,432 men died from a range of causes.

In general, people who frequently drank coffee were more likely to smoke and drink alcohol. To separate the effects of coffee from smoking, researchers repeated their analysis among never-smokers, and found that the protective benefits of coffee on deaths became even more evident.

“Regular consumption of coffee can be included as part of a healthy, balanced diet,” said senior author Frank Hu, M.D., Ph.D., a Professor of Nutrition and Epidemiology at Harvard. “However, certain populations such as pregnant women and children should be cautious about high caffeine intake from coffee or other beverages.”

The study was not designed to show a direct cause and effect relationship between coffee consumption and dying from illness. So the findings should be interpreted with caution, researchers said. One potential drawback of the study design was that participants were asked to report how much coffee they drank, however researchers found the assessment to be reliable.

Previous studies found inconsistent associations between coffee drinking and risk of total and cause-specific death. This study adds to the literature that moderate coffee consumption may confer health benefits. However, more research is needed to determine how coffee affects the body and whether different types of coffee may play a role.

Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the association’s policy or position. The association makes no representation or guarantee as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations are available at www.heart.org/corporatefunding.

Quest Diagnostics Inc. (NYSE:DGX) offers the most extensive clinical testing network in the U.S. The Company's extensive test menu includes routine biological testing; complex and specialized molecular and gene-based testing, and anatomic pathology testing. These services primarily help identify disease or risk factors for disease and predict and monitor response to treatment.

Quest Diagnostics Inc. (NYSE:DGX) offers the most extensive clinical testing network in the U.S. The Company's extensive test menu includes routine biological testing; complex and specialized molecular and gene-based testing, and anatomic pathology testing. These services primarily help identify disease or risk factors for disease and predict and monitor response to treatment.