Cannabis: Just pain relief without the 'high'

Researchers have determined the exact dose of marijuana extract cannabidiol (CBD) for effective pain relief without the 'high' produced by THC. They have shown that CBD doesn't act via the CB1 receptor which is responsible for the euphoria associated with marijuana use. Rather, CBD acts via the receptor involved in anxiety (serotonin 5HT1A) and pain (Vanilloid TRPV1). They found that low doses of CBD were able to alleviate both pain and anxiety which are the two most common symptoms associated with chronic pain. This finding could pave the way for finding safe alternatives to opioids for pain relief.

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