I have reached the conclusion that the human nose might be involved in cooling of the brain. In this report, I first describe the clinical observations about ankyloglossia with deviation of the epiglottis and larynx (ADEL) with regard to sleep that I have made during my 30 years of otorhino-laryngological experience. Then I describe the physiology of the nose. Next I quote from reports on paradoxical sleep, or REM sleep, from Kitamura K (2009) and Jouvet M (1992). Finally, I present the conclusion that nasal respiration is indispensable to a deep and sound sleep that refreshes humans and promotes vitality.

Mukai, S. and Mukai, C. (1991) New Disease with Ankyloglossia and Dislocation of the Epiglottis and of the Larynx—Dyspnea of the Newborn and Suckling Infants. In: Takishima, H., Ed., Advances in the Biosciences, Pergamon Press, New York, 191-193.

Mukai, S., Mukai, C. and Asaoka, K. (1990) Congenital Ankyloglossia with Deviation of the Epiglottis and Larynx— Respiratory Insufficiency of the Children. Journal of Clinical Otolaryngology (Kyoto), 83, 1043-1065. (In Japanese with English Abstract)

Mukai, S. (2011) Tonsils Increases in Weight during Growth, Moreover There Are Gender Differences. Optimumtime of Tonsilectomy Is between Two to Four. Zetuyuchakushogakkaishi, Annals of the Ankyloglossia with Deviation of the Epiglottis and Larynx, 17, 19-26. (In Japanese)