Silencer® Select Pre-Designed & Validated siRNA

Description

The Silencer® Select siRNAs are classic 21-mers which incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemistry. A choice of Silencer® Select siRNAs are available—Pre-Designed or Validated. Silencer® Select Pre-Designed siRNAs are guaranteed-to-silence based on their proven design while the Silencer® Select Validated siRNAs are functionally tested to reduce target gene expression. Sets of Silencer® Select siRNA Libraries are also available in tubes or plate for high throughput screening. The Silencer® Select Positive and Negative Control RNAs should be included in every siRNA experiment.

The benefits of using Silencer® Select siRNAs include:

Potent—up to 100-fold more potent than currently available siRNAs and fewer off-target effects

Most Specific—LNA® chemical modifications reduce off-target effects by up to 90%

Reliable—demonstrated improvements in consistency and reliability of phenotypic results

Guaranteed—100% guaranteed to silence, the best guarantee in the industry

Note: Silencer® Pre-Designed & Validated siRNAs are designed using our first-generation algorithm and DO NOT include any chemical modifications. They are recommended for completing in vitro RNAi studies that were started using Silencer® siRNAs. For new studies we recommend Silencer Select siRNAs.

Approximate Turnaround Times*
Standard purification: 4 business days
HPLC purification: 6 business days (20 and 40 nmol); 15 business days (250 nmol)
In Vivo Ready: 15 business days (250 nmol)

Catalog #

Pre-designed/Validated

Purification

Size

4390817

Pre-designed

HPLC purified

20 nmol

4390818

Pre-designed

HPLC purified

40 nmol

4404014

Pre-designed

HPLC purified

250 nmol

4404010

Pre-designed

In Vivo Ready

250 nmol

4390815

Pre-designed non-inventoried

Standard purity

20 nmol

4390771

Pre-designed non-inventoried

Standard purity

5 nmol

4390816

Pre-designed non-inventoried

Standard purity

40 nmol

4392420

Pre-designed

Standard purity

5 nmol

4392421

Pre-designed

Standard purity

20 nmol

4392422

Pre-designed

Standard purity

40 nmol

4427037

Pre-designed

Standard purity

1 nmol

4390821

Validated

HPLC purified

20 nmol

4390822

Validated

HPLC purified

40 nmol

4407270

Validated

HPLC purified

250 nmol

4407267

Validated

In Vivo Ready

250 nmol

4390824

Validated

Standard purity

5 nmol

4390825

Validated

Standard purity

20 nmol

4390826

Validated

Standard purity

40 nmol

4427038

Validated

Standard purity

1 nmol

*Estimated time from order confirmation to ship date from Austin, TX for orders confirmed by 2 pm CST. Does not include time required for shipping (typically overnight for US and Canada deliveries, 2 days for Europe, 2-3 days elsewhere).