Should I Switch Off Azt

Thank you for providing this excellent source of HIV info.I am a 46 yo male, have been taking AZT, 3TC, and Sustiva for 18 months. VL is undetectable, CD4 28% 415, I feel healthy and exercise regularly. No sign of lipo-atrophy either. However...

Thank you for your post.The important thing to note is that you are doing great and in all likelihood will continue to do so as long as you take your medications consistently. At this point the decision to make a change is very much a personal one...
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...what the original study showed: The study evaluated a switch from d4T (stavudine, Zerit) to abacavir (ABC or ABV, Ziagen) or AZT (ZDV, zidovudine, Retrovir) in 118 patients with lipoatrophy. Some of the patients also had high lactic acid levels....
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...have been approved. Several are available under PEPFAR (see Fact Sheet 475 ). Zidovudine is also known as azidodeoxythymidine, AZT or ZDV. Zidovudine was the first drug approved for the treatment of HIV. It is a nucleoside analog reverse...
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...Several studies presented at the 4th National Conference on Retroviruses and Opportunistic Infections evaluated the effect of AZT resistance codon mutations on outcome. One of the most important studies presented by David Katzenstein and other...
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