@ARTICLE{Derakhshan,
author = {Derakhshan, Safoura and Navidinia, Masoumeh and Ahmadi, Amjad and },
title = {Antibacterial Activity of Dill (Anethum graveolens) Essential Oil and Antibiofilm Activity of Cumin (Cuminum cyminum) Alcoholic Extract},
volume = {3},
number = {4},
abstract ={Background: Emergence of drug-resistant bacteria has highlighted the need to identify new and more efficient antibacterial agents. The aims of this study were to evaluate the antibacterial activity of dill (Anethum graveolens) seeds essential oil and to investigate the effect of cumin (Cuminum cyminum) seeds alcoholic extract on biofilm formation ability of Klebsiella pneumoniae. Materials and methods: This experimental study was carried out at the Faculty of Medicine of Kurdistan University of Medical Sciences in 2014. Activity of dill seeds essential oil was evaluated based on the inhibition zone diameter and minimum inhibitory concentration (MIC) against some important pathogenic bacteria including: Vibrio cholerae, Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. Furthermore, the effect of sub-inhibitory concentrations of cumin seeds alcoholic extract was evaluated on biofilm formation ability of K. pneumoniae. The biofilms were formed on semi-glass lamellas and observed by a scanning electron microscope. Results: Dill essential oil showed a good to moderate activity against the tested strains. The highest antibacterial activity was observed against S. aureus (inhibition zone of 15 mm and MIC of 0.62 mg.mL-1) and V. cholerae (inhibition zone of 14 mm and MIC of 0.7 mg..mL-1). The cumin alcoholic extract had no effect on biofilm formation ability of K. pneumoniae. Conclusion: The results of this study showed the presence of antimicrobial compounds in dill extract. The cumin alcoholic extract was not able to inhibit biofilm formation ability of K. pneumoniae. Because of the medicinal plants properties, it is valuable to search for promising herbs and novel chemical compounds. },
URL = {http://journals.modares.ac.ir/article-4-6617-en.html},
eprint = {http://journals.modares.ac.ir/article-4-6617-en.pdf},
journal = {Infection Epidemiology and Microbiology},
doi = {},
year = {2017}
}