The ESP Timeline (one of the site's most popular features) has been
completely updated to allow the user to select (using the timeline controls
above each column) different topics for
the left and right sides of the display.

Christian Friedrich Nasse formulated Nasse's law: hemophilia occurs only in males and is passed on by unaffected females.

1820

André-Marie Ampère formulates one of the basic laws of electromagnetism, the right-hand rule for the influence of an electric current on the magnet and demonstrates that two wires that are carrying an electric current will attract or repel each other, depending on whether the occurrence are in opposite where the same directions.

Dominique-François Arago discovers the magnetic effect of electricity passing through a copper wire, demonstrating that iron is not necessary for magnetism.

Augustin-Jean Fresnel invents the so-called Fresnel lens, a lens used in lighthouses.

The science of electrodynamics is born with the announcement of Hans Christian Ørsted's discovery of electromagnetism.

(no entry for this year)

1821

(no entry for this year)

Etienne Geoffroy publishes Anatomical Philosophy discussing similarities between skeletal structures — such as bat wings, paws and hands — that support the evolutionary claims of Lamarck. He also argues that arthropods and vertebrates have similar but inverse body plans, an assertion that will ultimately be widely accepted.

Between 1822-1824, Thomas Andrew Knight, John Goss, and Alexander Seton all independently perform crosses with the pea and observe dominance in the immediate progeny, and segregation of various hereditary characters in the next generation. However, they do not study later generations or determine the numerical ratios in which the characters are transmitted.

1822

(no entry for this year)

Thomas Andrew Knight confirms reports of dominance, recessivity, and segregation in peas, but does not detect regularities.

1823

(no entry for this year)

(no entry for this year)

1824

Réflexions sur la puissance motrice du feu (On the motive power of fire) by Nicolas Léonard Sadi Carnot shows that work is done as heat passes from a high temperature to a low temperature; defines work; hints at the second law of thermodynamics; and suggests internal combustion engines.

(no entry for this year)

1825

(no entry for this year)

(no entry for this year)

1826

(no entry for this year)

Karl Ernst von Baer first demonstrated the mammalian ovum; he regarded the sperm cells as "Entozoa," i.e., parasites, and named them spermatozoa.

1827

Theory of systems of rays by William Rowan Hamilton is a unification of the study of optics through the principle of "varying action". It contains his correct prediction of conical refraction. When his prediction is verified, he becomes a well-known and is knighted.

A year after discovering the mammalian egg cell, Karl Ernst von Baer publishes Entwickelungsgeschichte der Thiere tracing the developmental history of animals.

Joseph Henry shows that passing an electric current through a wire wrapped into coils produces a greater magnetic field than is produced when that same current is passed through a straight wire, and that an insulated wire wrapped around an iron core can produce a powerful electromagnet.

ESP Quick Facts

ESP Origins

In the early 1990's,
Robert Robbins
was a faculty member at Johns
Hopkins, where he directed the informatics core of GDB
— the human gene-mapping database of the international human
genome project. To share papers with colleagues around the world, he
set up a small paper-sharing section on his personal web page. This
small project evolved into The Electronic Scholarly
Publishing Project.

ESP Support

In 1995, Robbins became the VP/IT of the Fred Hutchinson Cancer Research
Center in Seattle, WA. Soon after arriving in Seattle, Robbins secured
funding, through the ELSI component of the US Human Genome Project, to
create the original ESP.ORG web site, with the formal goal of
providing free, world-wide access to the literature of classical genetics.

ESP Rationale

Although the methods of molecular biology can seem almost
magical to the uninitiated, the original
techniques of classical genetics are readily appreciated by one and
all: cross individuals that differ in some inherited trait, collect
all of the progeny, score their attributes, and propose mechanisms
to explain the patterns of inheritance observed.

ESP Goal

In reading the early works of classical genetics, one is drawn, almost
inexorably, into ever more complex models, until molecular explanations
begin to seem both necessary and natural. At that point, the tools
for understanding genome research are at hand. Assisting readers reach
this point was the original goal of The Electronic Scholarly Publishing
Project.

ESP Usage

Usage of the site grew rapidly and has remained high. Faculty began
to use the site for their assigned readings. Other on-line
publishers, ranging from The New York Times to Nature
referenced ESP materials in their own publications. Nobel laureates
(e.g., Joshua Lederberg) regularly used the
site and even wrote to suggest changes and improvements.

ESP Content

When the site began, no journals
were making their early content available in
digital format. As a result, ESP was obliged to digitize classic
literature before it could be made available. For many important
papers — such as
Mendel's original paper
or the
first genetic map
— ESP had to produce entirely new typeset versions of the works,
if they were to be available in a high-quality format.

ESP Help

Early support from the DOE component of the Human Genome Project was
critically important for getting the ESP project on a firm foundation.
Since that funding ended (nearly 20 years ago), the project has been
operated as a purely volunteer effort.
Anyone wishing to assist in these efforts should send an
email to Robbins.