Alvesco® (ciclesonide) Inhalation Aerosol has small particles of
asthma medicine that are designed to reach deep into the airways — to deliver asthma medicine where it may
help to reduce asthma inflammation1,2†

* The Alvesco Savings Card program is not valid in the state of Vermont and the
Alvesco Savings Card is not eligible for
redemption by patients in Vermont.

** Most insured patients will pay no more than $5 monthly with a maximum benefit of $85 per fill.
Restrictions apply and
co-pay amounts may vary. Subject to eligibility rules; restrictions apply. This coupon is not valid for
prescriptions
that are eligible to be reimbursed, in whole or in part, by Medicaid, Medicare (including Medicare Part D
and Medicare
Advantage), TriCare, CHAMPUS, or any other local, state or federal healthcare programs, including state
prescription
drug assistance programs and the La Reforma de Salud program in Puerto Rico.

†Alvesco is indicated for the maintenance treatment of asthma as prophylactic therapy in
adult and adolescent patients 12 years of age and older.

Important Limitations of Use:

Alvesco is NOT indicated for the relief of acute bronchospasm

Alvesco is NOT indicated for children under 12 years of age

*Most insured patients will pay no more than $5 monthly with a maximum benefit of $85 per fill. Restrictions
apply and co-pay amounts may vary. Subject to eligibility rules; restrictions apply. This coupon is not valid
for prescriptions that are eligible to be reimbursed, in whole or in part, by Medicaid, Medicare (including
Medicare Part D and Medicare Advantage), TriCare, CHAMPUS, or any other local, state or federal healthcare
programs, including state prescription drug assistance programs and the La Reforma de Salud program in Puerto
Rico.

The Alvesco Savings Card program is not valid in the state of Vermont and the Alvesco Savings Card is not
eligible for redemption by patients in Vermont.

IMPORTANT SAFETY INFORMATIONThese highlights do not include all the information needed to use
ALVESCO safely and effectively. See Full
Prescribing Information for ALVESCO.

INDICATION for ALVESCO (ciclesonide) INHALATION AEROSOLALVESCO is for the long-term
treatment of asthma as preventative therapy in adults and adolescents 12 years of age and older. ALVESCO is
NOT indicated for the relief of acute bronchospasm. ALVESCO is NOT indicated for children under 12 years of
age.

IMPORTANT SAFETY INFORMATION FOR ALVESCOALVESCO is NOT a rescue inhaler and should not
be used for relief of sudden symptoms of shortness of breath during an asthma attack. Use a fast-acting rescue
medicine (such as a levalbuterol or albuterol inhaler) to relieve sudden symptoms if you have an asthma
attack. You should contact your healthcare professional if an asthma attack does not respond to your rescue
medicine or you need to use your rescue medicine more often than usual.

You should not use ALVESCO if you are allergic to ciclesonide or any of the ingredients in ALVESCO. Rare
cases of severe allergic reactions, including swelling of the lips, tongue and throat, have been reported.

Yeast infections of the mouth and throat (thrush) have occurred in some ALVESCO patients. Rinse your mouth
after you inhale each dose of ALVESCO. If you develop a yeast infection, it should be treated by a healthcare
professional.

Patients taking ALVESCO are at a possible increased risk of infection due to a weakened immune system that
may occur when taking a steroid medicine. Tell your healthcare professional if you have had tuberculosis (TB)
or any other infections before or while using ALVESCO, or if you are exposed to chickenpox or measles.

If you took an oral (by mouth) steroid previously and are having the dose decreased, or you have been
switched to ALVESCO from an oral steroid, tell your healthcare professional right away about any symptoms such
as feeling tired or exhausted, weakness, nausea, vomiting, or symptoms of low blood pressure (such as
dizziness or faintness). These may be symptoms of a potentially life-threatening condition in which your body
does not produce enough natural steroids.

Using inhaled steroid medicines for a long time may put you at greater risk for decreased bone mass (which
can cause bones to become weaker). Inhaled corticosteroids including ALVESCO may cause slowed growth in
children and adolescents. Your healthcare professional should monitor your bone health and the growth of
children and adolescents taking ALVESCO.

Glaucoma, increased pressure in the eye, and cataracts have been seen in patients who received inhaled
steroid medications, including ALVESCO. Your healthcare professional should monitor you especially if you have
a change in vision or have a history of increased pressure in the eye, glaucoma, and/or cataracts.

As with other inhaled asthma medicines, bronchospasm (a sudden squeezing of the airways) can occur, with
wheezing, right after you inhale your dose of ALVESCO. If this happens, stop using ALVESCO and use a rescue
medicine right away, such as levalbuterol or albuterol. You should also inform your healthcare professional
right away so that your asthma medicine can be re-evaluated.

It is important to take ALVESCO regularly, as prescribed. Do not stop treatment even if you are feeling
better, unless told to do so by your healthcare professional. You should contact your healthcare professional
if your symptoms do not improve after 4 weeks, or if your condition worsens at any time during treatment. DO
NOT inhale more doses or use your ALVESCO inhaler more often than you have been directed.

What are some of the possible side effects of ALVESCO?The most common side effects
with ALVESCO include headache, pain or irritation of the nose and throat, sinus infection, upper respiratory
infection (such as the common cold), joint pain, stuffy nose, leg or arm pain, and back pain.

To report SUSPECTED ADVERSE REACTIONS, contact Covis Pharma at 1-866-488-4423 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.