..The objective of this study was to demonstrate the use of the Heckman two-step method to assess and correct for bias due to missing health related quality of life (HRQL) surveys in a clinical study of acute coronary syndrome (ACS) patients...

The association between clinical integration of care and transfer of veterans with acute coronary syndromes from primary care VHA hospitals

..However, whether impaired HRR is associated with incident AF is unknown. We studied the association of impaired HRR with the development of incident AF, after controlling for demographic and clinical confounders...

..Research to improve the quality of emergency care can benefit from a more systematic consideration of the domains of quality and the research steps necessary to generate evidence and inform quality improvement efforts in practice...

A multimodal blood pressure control intervention in 3 healthcare systems

..However, no large studies have directly compared outcomes of primary angioplasty vs thrombolytic therapy as a function of institutional experience...

Implications of the failure to identify high-risk electrocardiogram findings for the quality of care of patients with acute myocardial infarction: results of the Emergency Department Quality in Myocardial Infarction (EDQMI) study

..This study examined the association between the parental decision to decline pneumococcal conjugate (PCV7) vaccinations and the risk of hospitalization due to pneumococcal disease or lobar pneumonia in children...

Trends in time to confirmation and recognition of new-onset hypertension, 2002-2006

..Variability in office-based blood pressure readings suggests that further improvements in recognition and treatment may be achieved with more specific automated approaches to identifying hypertension...

..57-0.64); and lowest with the environment domain (r = 0.38-0.43). Asthma control tools reflect the symptoms and activity themes of asthma quality of life well, but reflect the environmental domain less well...

..The objective of this study was to determine if children who contracted pertussis infection were more likely to have parents who refused pertussis vaccinations than a similar group of children who did not develop pertussis infection...

Medication nonadherence is associated with a broad range of adverse outcomes in patients with coronary artery disease

..Little is known about the effect of nonadherence among patients with coronary artery disease (CAD) on a broad spectrum of outcomes including cardiovascular mortality, cardiovascular hospitalizations, and revascularization procedures...

Parental refusal of varicella vaccination and the associated risk of varicella infection in children

Marsha A RaebelClinical Research Unit, Kaiser Permanente of Colorado, and the School of Pharmacy, University of Colorado, Denver, Colorado 80237 8066, USAPharmacotherapy 25:1055-61. 2005

..To determine the frequency of monitoring of international normalized ratio (INR) within 14 days of coprescription of warfarin and antimicrobial therapy and to evaluate differences in INR monitoring among antimicrobials...

Laboratory monitoring of drugs at initiation of therapy in ambulatory care

..Little is known about the determinants of health-related quality of life after coronary artery bypass surgery. We determined the predictors of overall physical and mental health status 6 months after the operation...

Association of exercise capacity on treadmill with future cardiac events in patients referred for exercise testing

..Patient satisfaction is increasingly recognized as a quality indicator and important outcome of care. Little is known about the clinical factors associated with satisfaction after myocardial infarction (MI)...

..The association of obesity with asthma outcomes is not well understood...

Impact of delay in door-to-needle time on mortality in patients with ST-segment elevation myocardial infarction

Robert L McNamaraDepartment of Medicine, Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT, USAAm J Cardiol 100:1227-32. 2007

..87, respectively; p for trend <0.001). In conclusion, timely administration of fibrinolytic therapy continues to significantly impact on mortality in the modern era, particularly in patients presenting early after symptom onset...

Strategies for reducing the door-to-balloon time in acute myocardial infarction

Elizabeth H BradleyDepartment of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USAN Engl J Med 355:2308-20. 2006

..However, few hospitals meet this objective. We sought to identify hospital strategies that were significantly associated with a faster door-to-balloon time...

..Women reported significantly worse health status than men, but the differences observed were small and were attenuated after adjusting for socioeconomic status, smoking, body mass index, and comorbid illness...

Patient sex and quality of ED care for patients with myocardial infarction

..Medication nonadherence may reduce the effectiveness of therapies. To our knowledge, the association between medication nonadherence and mortality remains unexplored outside the context of clinical trials...

Elizabeth H BradleySection of Health Policy and Administration, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USACrit Pathw Cardiol 6:91-7. 2007

..In conclusion, although evidence of "what works" is based on observational studies rather than randomized trials, there is evidence on effective interventions to reduce door-to-balloon time...

The relationship between gender and clinical management after exercise stress testing

..Although it is known that reperfusion therapy for ST-elevation myocardial infarction (STEMI) is underused, the reasons for the failure to provide this potentially life-saving treatment are not well described...