Ronnie Brown also rushed for two TDs for the Tigers (8-0, 5-0 SEC), who overpowered the league's worst defense to overcome a stretch of sloppy play.

Auburn began the week by debuting at No. 4 in the Bowl Championship Series standings. The Tigers capped it with their fifth straight blowout win courtesy of a powerful running game and the nation's No. 2 scoring defense.

The Wildcats (1-6, 0-4) have dropped five consecutive games and 14 in a row against the Tigers.

Williams needed only 17 carries for his first 100-yard game in six weeks and third of the season. He scored on runs of 1 and 9 yards in the first quarter as Auburn opened up a 21-0 lead in the first 10:29.

Brown finished with 53 yards, including scoring runs of 12 and 17 yards. Jason Campbell completed 11 of 15 passes for 127 yards but all three offensive stars sat out the fourth quarter.

Redshirt freshman Andre' Woodson was sacked eight times in his first start at quarterback for Kentucky with Shane Boyd sidelined by a shoulder injury. He was 14-of-26 passing for only 73 yards and lost two fumbles, the second returned for a late 15-yard score by Kevis Burnam.

The Commodores (2-5) were outgained by the Colonels 460 yards to 366 yards, but they were able to keep Eastern Kentucky from converting after it broke midfield.

Cutler completed 15 of 21 passes for 156 yards and a touchdown. It was his fifth straight game without an interception. He also rushed for 73 yards and a touchdown.

The loss for Eastern Kentucky (3-4) snapped a three-game winning streak. C.J. Hudson had 107 rushing yards and caught a 45-yard touchdown pass for the Colonels.

Josh Greco completed 20 of 29 passes for 262 yards and a touchdown. The Commodores scored the final points of the game on the opening drive of the third quarter, going 77 yards in 11 plays before freshman Jeff Jennings ran in from a yard out.

Eastern Kentucky had one final chance to threaten Vanderbilt, but a fourth-down pass at the Vanderbilt one fell incomplete with just under six minutes remaining.

* No. 18 LSU 24, TROY ST. 20: At Baton Rouge, La., LSU quarterback Marcus Randall found David Jones for a 29-yard touchdown late in the fourth quarter and the No. 18-ranked Tigers avoided an upset at Tiger Stadium.

Troy State's Greg Whibbs kicked a 24-yard field goal to give the Trojans a 20-17 lead late in the game, but it didn't stand.