Congrats. If you don't already have one, I'd suggest getting a baby wipe warmer. It sounds ridiculous (I scoffed at my wife for mentioning it), but it will cut down on his protests and dramatically increase the amount of time you'll be able to sleep.

...and don't sweat the destruction. I have two girls and I quickly realised two things:

1) Get in there early. My firstborn (3 and a half now) has always understood that under no circumstances is she to touch daddy's toys. She asks me questions about them sometimes, but knows never to touch for now.2) FAR more importantly, I realised that - actually - as long as they don't hurt themselves I honestly couldn't care less what happens to my toys!