The man was shot around 8:15 p.m. in the 6400 block of Simpson Avenue in West College Hill.

Investigators are looking for two black men around 20 years old, police said. One man is described as being about 5 feet 8 inches, 160 pounds and wearing a blue hoodie with white stripes on the sleeves.

The second man is described as being 5 feet 10 inches with a slim build, wearing a gray hoodie and green shorts with white trim.

The men were last seen running east on Highland Avenue.

The identity of the man who was killed has not been released. He was taken to Mercy Mt. Airy Hospital, where he was pronounced dead.

Anyone with information about the case is asked to call police at 513-729-1300 or Crime Stoppers at 513-352-3040.