Scientific Publications

Abstract: In the Western world, malignant mesothelioma (MM) is most prevalent in the pleura of older males who have been professionally exposed to asbestos. Information about MM from rapidly industrializing countries such as China is minimal.

Abstract: The reported incidence of malignant mesothelioma (MM) in China is 1.5 cases per million population, much lower than in other countries. In China, the prevalence of MM in different regions is unknown, and only 15% of MMs have been associated with asbestos exposure compared with more than 70% in most of the world.

Proceedings of the National Academy of Sciences of the United States of America

Abstract: We found that gene mutations/deletions are frequent in mesothelioma and occur through a variety of DNA alterations. We identified genes implicated in malignant mesothelioma: SETD2, SMARCC1, PBRM1.

Abstract: Malignant mesothelioma (MM) is an aggressive cancer largely associated with asbestos exposure. In this review, we discuss the significant advancements in our understanding of its genetics and molecular biology and their translational relevance.

Abstract: On November 9 and 10, 2015, the InternationalConference on Mesothelioma in Populations Exposed to Naturally Occurring Asbestiform Fibers was held at the University of Hawaii Cancer Center in Honolulu, Hawaii.

Abstract: The differential diagnosis between pleural malignantmesothelioma (MM) and lung cancer is often challenging. Immunohistochemical (IHC) stains used to distinguish these malignancies include markers that are most often positive in MM and less frequently positive in carcinomas, and vice versa.

Abstract: Similar to asbestos fibers, non-regulated mineral fibers can cause malignant mesothelioma (MM). Recently, increased proportions of women and young individuals with MM were identified in southernNevada, suggesting that environmental exposure to carcinogenic fibers was causing the development of MM.