Pre_GI: SWBIT SVG BLASTN

Query: NC_012125:1897611 Salmonella enterica subsp. enterica serovar Paratyphi C strainLineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; BacteriaGeneral Information: The genome of this strain harbors a large pathogenicity island, SPI7, with genes coding for the Vi (virulence) antigen and other genes potentially associated with virulence. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

General Information: This bacterium is the causative agent of Fire Blight, a destructive disease of Maloid fruit trees, such as apple and pear. Outbreaks are sporadic in the Northeast, but result in serious damage to roots, blossoms, fruit, and shoots when they occur. The pathogen overwinters in cankers or in smaller limbs. During early spring, in response to both temperature increases and bud development, the bacteria multiplies and may be seen as a yellowish ooze around the perimeter of the canker. Flies and other insects are attracted to the ooze and disperse the inoculum to other trees in the orchard. This species has recently become resistant to streptomycin, an antibiotic traditionally used in its control.