Passignano was home to a historic Italian airplane factory, the SAI Ambrosini, now abandoned as an industrial center but still used as an association center. Its buildings still exist near the Passignano sul Trasimeno railway station.

Aircraft were tested at Eleuteri airport, only a few kilometers away from the factory. SAI was involved mainly with Macchi during World War II, although Eleuteri was also used as a test center for the Ambrosini SS.4.