The 2017 Galaxy Community Conference (GCC2017) is being held in Montpellier, France, 26-30 June. GCC2017 will include keynotes and accepted talks, poster sessions, demos, birds-of-a-feather meetups, exhibitors, and plenty of networking opportunities. There will also be three days of pre-conference activities, including hackathons and training. If you work in data-intensive biomedical research, there is no better place than GCC2017 to present your work and to learn from others.

Sign up or log in to save this to your schedule and see who's attending!

AbstractCervical cancer is the fourth most common cancer in women, and the seventh overall, with an estimated 528,000 new cases in 2012 and is the third most common in Brazil, with estimates of 16,340 in 2016. It accounted in 2012 for 7.5% of deaths by cancer in women.

International consortiums focused on cancer genomes have been using large-scale molecular techniques, generating a huge amount of data, publicly available, allowing new approaches on data analysis. TCGA has more than 2.5 petabytes of data of 11,000 tumor samples. The integration of many large-scale analysis allows a very complete view of cancer molecular basis. However, we need integrative bioinformatics analysis, done by experienced programmers on genomics. In the other hand, we have computational languages representation in an abstract manner by using workflows.

Barretos Cancer Hospital took part on the consortium as a tissue sample. We are willing to analyze the TCGA data, comparing to the Brazilian population and for this we chose Galaxy because it is a free platform that allows access by the web using reproductive workflows, storying all the provenance data, solving the reproducibility problem. Can also be installed locally in a computer or a server.

For this project we want to focus on analyzing DNA sequencing, methylation and gene expression, possibly identify biomarkers that can characterize people in risk for cervical cancer as well as compare molecular data with clinical-pathological characteristics. The protocol is approved by our ethical committee.