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Antibiotic use prevalent in hospice patients despite limited evidence of its valueNew research suggests that use of antibiotics is still prevalent among terminal patients who have chosen hospice care as an end-of-life option, despite little evidence that the medications improve symptoms or quality of life, and sometimes may cause unwanted side effects.http://medicalxpress.com/news/2014-07-antibiotic-prevalent-hospice-patients-limited.html
MedicationsMon, 14 Jul 2014 13:18:58 EDTnews324562728Researchers uncover new knowledge about our intestinesResearchers from Technical University of Denmark Systems Biology have mapped 500 previously unknown microorganisms in human intestinal flora as well as 800 also unknown bacterial viruses (also called bacteriophages) which attack intestinal bacteria.http://medicalxpress.com/news/2014-07-uncover-knowledge-intestines.html
GeneticsSun, 06 Jul 2014 13:00:02 EDTnews323855849Inappropriate use of antibiotics in ERs remains high for adults(HealthDay)—For patients presenting to the emergency department with acute respiratory tract infections (ARTI), inappropriate utilization of antibiotics has decreased for children, but not for adults, according to a study published online Dec. 16 in Antimicrobial Agents and Chemotherapy.http://medicalxpress.com/news/2014-01-inappropriate-antibiotics-ers-high-adults.html
MedicationsFri, 31 Jan 2014 12:00:01 EDTnews310389962New drug candidates show promise for cure for Chagas diseaseA team of researchers from Canada has developed a class of compounds which may help eradicate a neglected tropical disease that is currently hard to kill in its chronic form. The research was published ahead of print in Antimicrobial Agents and Chemotherapy.http://medicalxpress.com/news/2013-12-drug-candidates-chagas-disease.html
Diseases, Conditions, SyndromesThu, 26 Dec 2013 11:54:25 EDTnews307281250Disarming HIV with a 'pop': Researchers create molecule that can trick HIV into destroying itselfPinning down an effective way to combat the spread of the human immunodeficiency virus, the viral precursor to AIDS, has long been challenge task for scientists and physicians, because the virus is an elusive one that mutates frequently and, as a result, quickly becomes immune to medication. A team of Drexel University researchers is trying to get one step ahead of the virus with a microbicide they've created that can trick HIV into "popping" itself into oblivion.http://medicalxpress.com/news/2013-09-hiv-molecule.html
HIV & AIDSThu, 19 Sep 2013 12:43:46 EDTnews298813417More and more Danes infected with MRSA bacteriaIn 2012, 1,556 Danes were found positive with methicillin-resistant staphylococci - MRSA. This represents an increase of 20% from 2011. In fact, the total number of cases has almost doubled since 2009. MRSA bacteria are resistant to antimicrobial agents that are essential for treatment of treating life-threatening infections in humans.http://medicalxpress.com/news/2013-09-danes-infected-mrsa-bacteria.html
Diseases, Conditions, SyndromesThu, 19 Sep 2013 09:30:02 EDTnews298799518Novel vaccine reduces shedding of genital herpes virusSexually transmitted infection researchers potentially have reached a milestone in vaccine treatment for genital herpes, according to a report to be presented at the Interscience Conference on Antimicrobial Agents and Chemotherapy in Denver, Colo., on today, Sept. 12.http://medicalxpress.com/news/2013-09-vaccine-genital-herpes-virus.html
MedicationsThu, 12 Sep 2013 09:27:09 EDTnews298196818New antibiotic shows promise for treating MRSA pneumoniaA drug approved just two years ago for treating bacterial infections may hold promise for treating the potentially fatal MRSA pneumonia, according to a Henry Ford Hospital study.http://medicalxpress.com/news/2013-09-antibiotic-mrsa-pneumonia.html
MedicationsWed, 11 Sep 2013 13:00:06 EDTnews298116365Antibiotic resistance among hospital-acquired infections is much greater than prior CDC estimatesThe rise of antibiotic resistance among hospital-acquired infections is greater than the Centers for Disease Control and Prevention (CDC) found in its 2008 analysis, according to an ahead-of-print article in the journal, Antimicrobial Agents and Chemotherapy.http://medicalxpress.com/news/2013-08-antibiotic-resistance-hospital-acquired-infections-greater.html
Diseases, Conditions, SyndromesThu, 01 Aug 2013 11:05:01 EDTnews294573892Antibiotic reduction campaigns do not necessarily reduce resistanceAntibiotic use—and misuse—is the main driver for selection of antibiotic resistant bacteria. This has led many countries to implement interventions designed to reduce overall antibiotic consumption. Now, using methicillin resistant Staphylococcus aureus (MRSA) as an example, Laura Temime of the Conservatoire National des Arts et Metiers, Paris, and collaborators warn that simply reducing antibiotics consumption does not necessarily reduce resistance. The research is published online ahead of print in Antimicrobial Agents and Chemotherapy.http://medicalxpress.com/news/2013-07-antibiotic-reduction-campaigns-necessarily-resistance.html
Diseases, Conditions, SyndromesMon, 29 Jul 2013 12:09:28 EDTnews294318559Antibiotics: Change route of delivery to mitigate resistanceNew research suggests that the rapid rise of antibiotic resistance correlates with oral ingestion of antibiotics, raising the possibility that other routes of administration could reduce the spread of resistance. The manuscript appears online ahead of print in the journal Antimicrobial Agents and Chemotherapy.http://medicalxpress.com/news/2013-06-antibiotics-route-delivery-mitigate-resistance.html
Medical researchWed, 26 Jun 2013 16:07:30 EDTnews291481641HIV-derived antibacterial shows promise against drug-resistant bacteriaA team of researchers at the University of Pittsburgh has developed antibacterial compounds, derived from the outer coating of HIV, that could be potential treatments for drug-resistant bacterial infections and appear to avoid generating resistance. These new agents are quite small, making them inexpensive and easy to manufacture. The research was published in the June 2013 issue of the journal Antimicrobial Agents and Chemotherapy.http://medicalxpress.com/news/2013-06-hiv-derived-antibacterial-drug-resistant-bacteria.html
Medical researchWed, 19 Jun 2013 15:20:03 EDTnews290871996Discovery holds potential in destroying drug-resistant bacteriaThrough the serendipity of science, researchers at the University of Pittsburgh have discovered a potential treatment for deadly, drug-resistant bacterial infections that uses the same approach that HIV uses to infect cells. The National Institutes of Health-supported discovery will be described in the June issue of the journal Antimicrobial Agents and Chemotherapy. It is especially promising in the development of a potential treatment for lung infections in people with cystic fibrosis.http://medicalxpress.com/news/2013-05-discovery-potential-drug-resistant-bacteria.html
Medical researchTue, 07 May 2013 15:25:26 EDTnews287159117Scientists use nature against nature to develop an antibiotic with reduced resistanceA new broad range antibiotic, developed jointly by scientists at The Rockefeller University and Astex Pharmaceuticals, has been found to kill a wide range of bacteria, including drug-resistant Staphylococcus (MRSA) bacteria that do not respond to traditional drugs, in mice. The antibiotic, Epimerox, targets weaknesses in bacteria that have long been exploited by viruses that attack them, known as phage, and has even been shown to protect animals from fatal infection by Bacillus anthracis, the bacteria that causes anthrax.http://medicalxpress.com/news/2013-04-scientists-nature-antibiotic-resistance.html
MedicationsWed, 10 Apr 2013 17:00:02 EDTnews284831058New study identifies unique mechanisms of antibiotic resistanceAs public health authorities across the globe grapple with the growing problem of antibiotic resistance, Tufts University School of Medicine microbiologists and colleagues have identified the unique resistance mechanisms of a clinical isolate of E. coli resistant to carbapenems. Carbapenems are a class of antibiotics used as a last resort for the treatment of disease-causing bacteria, including E. coli and Klebsiella pneumonia, which can cause serious illness and even death. Infections involving resistant strains fail to respond to antibiotic treatments, which can lead to prolonged illness and greater risk of death, as well as significant public health challenges due to increased transmission of infection. The study, published in the April issue of Antimicrobial Agents and Chemotherapy, demonstrates the lengths to which bacteria will go to become resistant to antibiotics.http://medicalxpress.com/news/2013-03-unique-mechanisms-antibiotic-resistance.html
Diseases, Conditions, SyndromesTue, 26 Mar 2013 11:06:11 EDTnews283514765Newer, shorter-course antibiotic shows similar effectiveness for treating skin infectionTreatment with a newer antibiotic, tedizolid phosphate, once daily for 6 days was statistically noninferior (no worse than) in efficacy to the antibiotic linezolid twice daily for 10 days for both early (at day 2 to 3) and sustained (at day 11) clinical responses in patients with acute bacterial skin and skin structure infections, according to a study appearing in the February 13 issue of JAMA.http://medicalxpress.com/news/2013-02-shorter-course-antibiotic-similar-effectiveness-skin.html
Diseases, Conditions, SyndromesTue, 12 Feb 2013 16:30:02 EDTnews279906626'Repurposed' anti-parasite drug shows promise as new TB treatment(Medical Xpress)—A well-established family of drugs used to treat parasitic diseases is showing surprising potential as a therapy for tuberculosis (TB), according to new research from University of British Columbia microbiologists.http://medicalxpress.com/news/2012-11-repurposed-anti-parasite-drug-tb-treatment.html
Diseases, Conditions, SyndromesFri, 23 Nov 2012 07:58:29 EDTnews272879872Antibiotics disrupt gut flora in infants: Recovery still incomplete after 8 weeksEight weeks after antibiotic treatment of infants, the diversity of gastrointestinal flora remained diminished, although the number of individual bacteria was back to normal, according to a paper in the November 2012 issue of the journal Antimicrobial Agents and Chemotherapy. Additionally, the potentially disease-causing Proteobacteria were now the dominant population in the treated infants.http://medicalxpress.com/news/2012-11-antibiotics-disrupt-gut-flora-infants.html
MedicationsFri, 09 Nov 2012 07:33:53 EDTnews271668821Novel non-antibiotic agents against MRSA and common strep infectionsMenachem Shoham, PhD, associate professor of biochemistry at Case Western Reserve University School of Medicine, has discovered novel antivirulence drugs that, without killing the bacteria, render Methicillin Resistant Staphylococcus Aureus (MRSA) and Streptococcus pyogenes, commonly referred to as strep, harmless by preventing the production of toxins that cause disease. The promising discovery was presented this week at the Interscience Conference on Antimicrobial Agents and Chemotherapy in San Francisco.http://medicalxpress.com/news/2012-09-non-antibiotic-agents-mrsa-common-strep.html
Medical researchWed, 12 Sep 2012 13:38:53 EDTnews266675906Research finds novel airborne germ-killing oral spray effective in fighting colds and fluUniversity Hospitals Case Medical Center clinical researchers will present findings about a one-two punch to prevent colds and flu in San Francisco at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) on September 9, 2012.http://medicalxpress.com/news/2012-09-airborne-germ-killing-oral-effective-colds.html
Diseases, Conditions, SyndromesSun, 09 Sep 2012 14:38:43 EDTnews266420312Difficult to diagnose cases of infectious endocarditis solved with SPECT/CT imaging agentWhen combined with standard diagnostic tests, functional imaging procedures have been shown to reduce the rate of misdiagnosed cases of infectious endocarditis. According to new research published in the August issue of The Journal of Nuclear Medicine, single photon emission computed tomography (SPECT)/computed tomography (CT) with 99mTc-hexamethylpropleneamine oxime-labeled white blood cells (99mTc-HMPAO-WBC) can improve the diagnosis of infectious endocarditis in hard-to-diagnose cases.http://medicalxpress.com/news/2012-08-difficult-cases-infectious-endocarditis-spectct.html
Diseases, Conditions, SyndromesWed, 01 Aug 2012 13:40:45 EDTnews263047228UVC light kills wound bacteriaUltraviolet (UVC) light can eradicate wound-infecting bacteria on mice increasing both survival and healing rates, according to a paper in the July 2012 issue of Antimicrobial Agents and Chemotherapy. The light did not damage the animals' skin or delay wound healing, says principal investigator Michael R. Hamblin, of the Massachusetts General Hospital, and the Harvard Medical School, Boston, MA.http://medicalxpress.com/news/2012-07-uvc-wound-bacteria.html
Medical researchMon, 23 Jul 2012 08:40:01 EDTnews262250647Antibiotics boost risk of infection with antifungal-resistant candidaPrevious exposure to certain antibiotics could boost the risk of infection with drug-resistant strains of a severe fungal infection. Researchers report their findings in the May 2012 issue of the journal Antimicrobial Agents and Chemotherapy.http://medicalxpress.com/news/2012-05-antibiotics-boost-infection-antifungal-resistant-candida.html
MedicationsTue, 22 May 2012 09:00:04 EDTnews256894390Researchers closer to the super bug puzzleInfectious diseases specialists from Austin Health are working closely with Microbiologists from the University of Melbourne to understand how Staph is becoming resistant to all antibiotic therapies.http://medicalxpress.com/news/2011-11-closer-super-bug-puzzle.html
Diseases, Conditions, SyndromesFri, 11 Nov 2011 12:53:36 EDTnews240238390Newly discovered reservoir of antibiotic resistance genesWaters polluted by the ordure of pigs, poultry, or cattle represent a reservoir of antibiotic resistance genes, both known and potentially novel. These resistance genes can be spread among different bacterial species by bacteriophage, bacteria-infecting viruses, according to a paper in the October Antimicrobial Agents and Chemotherapy.http://medicalxpress.com/news/2011-10-newly-reservoir-antibiotic-resistance-genes.html
Medical researchFri, 21 Oct 2011 10:09:22 EDTnews238410548Gene therapy reduces HIV levels in small trials(Medical Xpress) -- This weekend at the Interscience Conference on Antimicrobial Agents and Chemotherapy in Chicago, Illinois, researchers from two different study groups, one on the east coast and one on the west coast, reported promising results from studies being conducted in gene therapy for the treatment of HIV.http://medicalxpress.com/news/2011-09-gene-therapy-hiv-small-trials.html
HIV & AIDSTue, 20 Sep 2011 14:20:06 EDTnews235744975Growing concern over drugs fed to animals Drugs fed to animals to promote growth and prevent diseases may play a key role in the emergence of antibiotic resistant bacteria, microbiologists said Sunday.http://medicalxpress.com/news/2011-09-drugs-fed-animals.html
Diseases, Conditions, SyndromesMon, 19 Sep 2011 03:46:08 EDTnews235622757Drug-resistant bacteria top agenda of medical conventionThe emergence of bacteria resistant to antibiotics and efforts by scientists trying to cope with the problem top the agenda at a medical convention under way here this weekend.http://medicalxpress.com/news/2011-09-drug-resistant-bacteria-agenda-medical-convention.html
HealthSun, 18 Sep 2011 13:40:27 EDTnews235572007Research provides insight into new drug resistance in hospital microbesHospitals struggle to prevent the infections that complicate treatment for cancer, joint replacement, heart surgery and other conditions. Hospital-acquired infections are often resistant to multiple antibiotics, leading to approximately 100,000 deaths and more than $30 billion in additional health care costs yearly. New drugs are being developed to combat these infections, but resistance invariably emerges to these last-line drugs.http://medicalxpress.com/news/2011-07-insight-drug-resistance-hospital-microbes.html
Medical researchWed, 13 Jul 2011 15:29:37 EDTnews229789767Old is new again: Study determines dosing for 1950s drug now being used to treat drug-resistant infections(Medical Xpress) -- An ongoing study led by a University of Pittsburgh researcher has established the first scientifically-based dosing guidelines for a more than 50-year-old drug that has re-emerged as the best, and often only, treatment for some bacterial infections that are resistant to modern therapies. The study appears in the July issue of the journal Antimicrobial Agents and Chemotherapy.http://medicalxpress.com/news/2011-07-dosing-1950s-drug-drug-resistant-infections.html
MedicationsMon, 04 Jul 2011 07:05:06 EDTnews228981859