Aims. The program is designed to better characterize the variety of clinical manifestations of ADHD over time. At OHSU, we see ADHD as comprising several conditions currently hidden under one umbrella diagnosis, analogously to how mental retardation (now called intellectual disability) or cancer were once seen as single diseases. The program is following a cohort of over 600 children from the greater Portland area, who are in the process of completing clinical, neuropsychological, physiological, and biological measurements on an annual or semi-annual basis. Over time, this effort will enable us to characterize the wide variety of physiological "types" that likely exist within ADHD, as well as the range of clinical outcomes. To date, we have already been able to identify promising typologies, integrate the role of emotional and cognitive difficulties, and initiate short term clinical prediction that can improve on existing clinical tools.

Productivity. To date this arm of the program has generated over 25 publications and an equal number of conference presentations, helping the field to recognize the possibilities for richer characterization of this complex condition.