I am from the UK (London) and I will be travelling to the Colorado, USA next March to bake and decorate my friend's wedding cake for her!

I have never been to the USA before, and will hopefully be bringing most of the dry ingredients with me. However, I wanted to know whether there are any major differences between baking in the different countries?

I will be baking both sponge and chocolate cakes and decorating them with sugar paste / rolled fondant. I have been told altitude may play a role, but this is unlikely as I shouldn't be too high up!

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I would not think that there is no difference exist while baking cake in UK and US.Not only for these countries, for all the countries the cake baking is same only.

Altitude definately makes a difference in baking. There are slight modifications you can make to baking recipes for high elevations. Check it out on the internet. I'm sure there is informations somewhere.
Again is will depend on where in Colorado. Most of Colorado is higher elevation, after all there are Rocky Mountains running through it.