Fusion

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Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

tyrS

Tyrosyl-tRNA synthetase ; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (428 aa)

Predicted Functional Partners:

PBAL39_07115

Phenylalanyl-tRNA synthetase beta subunit (799 aa)

0.913

PBAL39_10900

Methionyl-tRNA synthetase ; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (716 aa)

Alanyl-tRNA synthetase ; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (900 aa)

0.796

PBAL39_11952

Secretion chaperone (111 aa)

0.770

gltX

Glutamyl-tRNA synthetase ; Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction- glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (502 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

PBAL39_03729

PBAL39_07115

PBAL39_03729

PBAL39_07115

Phenylalanyl-tRNA synthetase alpha subunit

Phenylalanyl-tRNA synthetase beta subunit

0.999

PBAL39_03729

PBAL39_08891

PBAL39_03729

PBAL39_08891

Phenylalanyl-tRNA synthetase alpha subunit

Cysteinyl-tRNA synthetase

0.458

PBAL39_03729

PBAL39_10900

PBAL39_03729

PBAL39_10900

Phenylalanyl-tRNA synthetase alpha subunit

Methionyl-tRNA synthetase ; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation

0.990

PBAL39_03729

PBAL39_11952

PBAL39_03729

PBAL39_11952

Phenylalanyl-tRNA synthetase alpha subunit

Secretion chaperone

0.958

PBAL39_03729

PBAL39_18189

PBAL39_03729

PBAL39_18189

Phenylalanyl-tRNA synthetase alpha subunit

Alanyl-tRNA synthetase ; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain

0.853

PBAL39_03729

gltX

PBAL39_03729

PBAL39_11807

Phenylalanyl-tRNA synthetase alpha subunit

Glutamyl-tRNA synthetase ; Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction- glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)

0.565

PBAL39_03729

glyQS

PBAL39_03729

PBAL39_21710

Phenylalanyl-tRNA synthetase alpha subunit

Glycyl-tRNA synthetase ; Catalyzes the attachment of glycine to tRNA(Gly)

0.417

PBAL39_03729

hisS

PBAL39_03729

PBAL39_10331

Phenylalanyl-tRNA synthetase alpha subunit

Histidyl-tRNA synthetase

0.674

PBAL39_03729

leuS

PBAL39_03729

PBAL39_23973

Phenylalanyl-tRNA synthetase alpha subunit

Leucyl-tRNA synthetase

0.640

PBAL39_03729

tyrS

PBAL39_03729

PBAL39_21935

Phenylalanyl-tRNA synthetase alpha subunit

Tyrosyl-tRNA synthetase ; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)

0.702

PBAL39_07115

PBAL39_03729

PBAL39_07115

PBAL39_03729

Phenylalanyl-tRNA synthetase beta subunit

Phenylalanyl-tRNA synthetase alpha subunit

0.999

PBAL39_07115

PBAL39_08891

PBAL39_07115

PBAL39_08891

Phenylalanyl-tRNA synthetase beta subunit

Cysteinyl-tRNA synthetase

0.808

PBAL39_07115

PBAL39_10900

PBAL39_07115

PBAL39_10900

Phenylalanyl-tRNA synthetase beta subunit

Methionyl-tRNA synthetase ; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation

0.999

PBAL39_07115

PBAL39_11952

PBAL39_07115

PBAL39_11952

Phenylalanyl-tRNA synthetase beta subunit

Secretion chaperone

0.813

PBAL39_07115

PBAL39_18189

PBAL39_07115

PBAL39_18189

Phenylalanyl-tRNA synthetase beta subunit

Alanyl-tRNA synthetase ; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain

0.985

PBAL39_07115

gltX

PBAL39_07115

PBAL39_11807

Phenylalanyl-tRNA synthetase beta subunit

Glutamyl-tRNA synthetase ; Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction- glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)

0.956

PBAL39_07115

glyQS

PBAL39_07115

PBAL39_21710

Phenylalanyl-tRNA synthetase beta subunit

Glycyl-tRNA synthetase ; Catalyzes the attachment of glycine to tRNA(Gly)

0.726

PBAL39_07115

hisS

PBAL39_07115

PBAL39_10331

Phenylalanyl-tRNA synthetase beta subunit

Histidyl-tRNA synthetase

0.817

PBAL39_07115

leuS

PBAL39_07115

PBAL39_23973

Phenylalanyl-tRNA synthetase beta subunit

Leucyl-tRNA synthetase

0.855

PBAL39_07115

tyrS

PBAL39_07115

PBAL39_21935

Phenylalanyl-tRNA synthetase beta subunit

Tyrosyl-tRNA synthetase ; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)

0.913

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Network Stats

Network Stats analysis is still ongoing, please wait ...

Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: