UV tattoo ink is not commonly known or used, as very few varieties of UV inks are approved for use in the US. It is also many times more expensive than regular tattoo inks. Some people have had reactions to ingredients in the ink, ranging from minor itching to dermatitis. Several UV inks are suspected carcinogens and allergens and at this time, no research has been conducted into the side effects of long term exposure.

Although many people who have received black light tattoos have had physical effects on the skin, any ink could cause a reaction. This can be a result of not protecting the tattoo from UV rays within 3 months of receiving the tattoo process or by using scented cremes or lotions on the tattoo area. This can damage the ink, causing it to become a normal ink color in all light. In time, it may also not glow in black lighting. Clear/blue UV inks are known to yellow or turn slightly brown with sun exposure. Color/black UV inks are known to become colored in all lighting. Therefore, it might permanently appear as a regular tattoo.

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