Abstract The present study used the preproenkephalin knockout (ppENK) mice to test whether the endogenous enkephalins deficit could facilitate the anxiety- and depressive-like symptoms of posttraumatic stress disorder (PTSD). On Day 1, sixteen wildtype (WT) and sixteen ppENK male mice were given a 3 mA or no footshock treatment for 10 seconds in the footshock apparatus, respectively. On Days 2, 7, and 13, all mice were given situational reminders for 1 min per trial, and the freezing response was assessed. On Day 14, all mice were tested in the open field test, elevated plus maze,...

(BQ) Part 2 book "Prevention of cardiovascular diseases from current evidence to clinical practice" presents the following contents: Chagas disease - A neglected disease; prevention and control of cardiovascular diseases - Policies, strategies and interventions; prevention and control of cardiovascular diseases focusing on low and middle ­income countries; posttraumatic stress disorder and cardiovascular disease,...

Consequences of agitation include self-extubation, removal of IV catheters, dyssynchrony
with mechanical ventilation, and, perhaps, a long-term risk of psychiatric problems, such
as delirium and posttraumatic stress disorder can be prevented by a proper sedation.
Prolonged and excessive sedation are problematic too, interfering with weaning from
mechanical ventilation and leading to increased rates of nosocomial pneumonia,
prolonged ICU stays, and difficulty identifying new problems, such as myocardial
infarction or stroke....

American men face a staggering array of health concerns. According
to the Centers for Disease Control and Prevention, 70 percent of
American men are overweight, a key predictor of future health problems.
Almost 25 percent smoke, another key risk factor. One in five
American men has heart disease, and 29 percent aged twenty and
older suffer from hypertension. More than 11 percent of men face a
limitation in their usual activities due to chronic health conditions.
In addition, the medical concerns men face often differ from those of
most concern to women.

Like phantom limbs that still can be felt even though they no longer exist,
the twin towers of the World Trade Center continue to haunt New Yorkers,
who – in the words of cartoonist Art Spiegelman (2004) – now live “in the
shadow of no towers.” During the first years of their absence, accounts of the
attack – including journalistic, governmental, academic, fictionalized, and cinematic
portrayals – proliferated. The multiplication of accounts is entirely warranted,
given that no single version can fully describe the attack’s antecedents,
manifestations, and ramifications.