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hyaluronan

What is the most important information I should know about hyaluronan?

Talk to your doctor before using hyaluronan if you have an allergy to birds or bird products, feathers, or chicken or egg products.

What is hyaluronan?

Hyaluronan is similar to synovial fluid, a substance that occurs naturally in the joints. Synovial fluid acts as a lubricant and shock absorber.

Hyaluronan is injected into the knee joints for the treatment of pain in individuals with osteoarthritis.

Hyaluronan may also be used for purposes other than those listed here.

What should I discuss with my health care provider before using hyaluronan?

Talk to your doctor before using hyaluronan if you have an allergy to birds or bird products, feathers, or chicken or egg products.

Hyaluronan should not be used if there is an infection or skin disease at the site of injection.

It is not known whether hyaluronan will be harmful to an unborn baby. Do not use hyaluronan without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether hyaluronan will be harmful to a nursing baby. Do not use hyaluronan without first talking to your doctor if you are breast-feeding a baby.

How should I use hyaluronan?

Hyaluronan is administered by a healthcare professional as an intra-articular (into the joint) injection.

Temporary pain or swelling of the affected joint may occur after injection of hyaluronan.

Avoid strenuous activity or prolonged (longer than one hour) weight-bearing activity such as jogging, tennis, lifting weights, or standing for 48 hours following an injection, unless otherwise directed by your doctor.

What happens if I miss a dose?

Contact your doctor if a dose of hyaluronan is missed.

What happens if I overdose?

An overdose of hyaluronan is unlikely to threaten life. Contact your doctor or seek emergency medical attention if an overdose of hyaluronan is suspected.

What should I avoid while using hyaluronan?

Avoid strenuous activity or prolonged (longer than one hour) weight-bearing activity such as jogging, tennis, lifting weights, or standing for 48 hours following an injection, unless otherwise directed by your doctor.

What are the possible side effects of hyaluronan?

Notify your doctor immediately if you experience a rare but serious allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives) to hyaluronan.

Other less serious side effects may also occur. Talk to your doctor if you experience

temporary pain or swelling of the affected joint;

rash or bruising at the injection site; or

an overall achy feeling.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect hyaluronan?

It is not known whether other medications will interact with hyaluronan. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products during treatment with hyaluronan.

Where can I get more information?

Your pharmacist has additional information about hyaluronan written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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