Fusion

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Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PP1S163_81V6.1

Predicted protein (927 aa)

Predicted Functional Partners:

brk1

Predicted protein (79 aa)

0.833

PP1S89_249V6.1

annotation not available (369 aa)

0.560

PP1S360_34V6.1

annotation not available (381 aa)

0.560

PP1S47_79V6.1

Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks (175 aa)

0.546

PP1S141_25V6.1

Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks (175 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

ARP1507

PP1S141_25V6.1

PP1S17_342V6.1

PP1S141_25V6.1

Actin related protein Arp2 subunit ; Belongs to the actin family

Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks

0.996

ARP1507

PP1S163_81V6.1

PP1S17_342V6.1

PP1S163_81V6.1

Actin related protein Arp2 subunit ; Belongs to the actin family

Predicted protein

0.532

ARP1507

PP1S360_34V6.1

PP1S17_342V6.1

PP1S360_34V6.1

Actin related protein Arp2 subunit ; Belongs to the actin family

annotation not available

0.686

ARP1507

PP1S441_22V6.2

PP1S17_342V6.1

PP1S441_22V6.2

Actin related protein Arp2 subunit ; Belongs to the actin family

annotation not available

0.801

ARP1507

PP1S47_79V6.1

PP1S17_342V6.1

PP1S47_79V6.1

Actin related protein Arp2 subunit ; Belongs to the actin family

Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks

0.996

ARP1507

PP1S7_387V6.1

PP1S17_342V6.1

PP1S7_387V6.1

Actin related protein Arp2 subunit ; Belongs to the actin family

annotation not available

0.801

ARP1507

PP1S89_249V6.1

PP1S17_342V6.1

PP1S89_249V6.1

Actin related protein Arp2 subunit ; Belongs to the actin family

annotation not available

0.686

ARP1507

brk1

PP1S17_342V6.1

PP1S35_157V6.1

Actin related protein Arp2 subunit ; Belongs to the actin family

Predicted protein

0.804

PP1S132_186V6.1

PP1S163_81V6.1

PP1S132_186V6.1

PP1S163_81V6.1

Predicted protein

Predicted protein

0.511

PP1S141_25V6.1

ARP1507

PP1S141_25V6.1

PP1S17_342V6.1

Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks

Actin related protein Arp2 subunit ; Belongs to the actin family

0.996

PP1S141_25V6.1

PP1S163_81V6.1

PP1S141_25V6.1

PP1S163_81V6.1

Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks

Predicted protein

0.546

PP1S141_25V6.1

PP1S360_34V6.1

PP1S141_25V6.1

PP1S360_34V6.1

Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks

annotation not available

0.670

PP1S141_25V6.1

PP1S441_22V6.2

PP1S141_25V6.1

PP1S441_22V6.2

Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks

annotation not available

0.617

PP1S141_25V6.1

PP1S47_79V6.1

PP1S141_25V6.1

PP1S47_79V6.1

Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks

Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks

0.800

PP1S141_25V6.1

PP1S7_387V6.1

PP1S141_25V6.1

PP1S7_387V6.1

Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks

annotation not available

0.617

PP1S141_25V6.1

PP1S89_249V6.1

PP1S141_25V6.1

PP1S89_249V6.1

Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks

annotation not available

0.670

PP1S141_25V6.1

brk1

PP1S141_25V6.1

PP1S35_157V6.1

Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks

Predicted protein

0.646

PP1S163_81V6.1

ARP1507

PP1S163_81V6.1

PP1S17_342V6.1

Predicted protein

Actin related protein Arp2 subunit ; Belongs to the actin family

0.532

PP1S163_81V6.1

PP1S132_186V6.1

PP1S163_81V6.1

PP1S132_186V6.1

Predicted protein

Predicted protein

0.511

PP1S163_81V6.1

PP1S141_25V6.1

PP1S163_81V6.1

PP1S141_25V6.1

Predicted protein

Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks

0.546

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: