Will Close presenting: In this presentation, we will go over the steps required to analyze community composition using metagenomics. Topics covered will include read quality control, assembly, binning, and classification. While this talk is framed around analyzing viral communities, the principles also apply to the study of other populations, including bacteria.

The resilience of the microbiome determines whether the community returns to the original steady state or to an altered state after perturbation. Microbiome resilience can have positive or negative outcomes for the host, including maintaining resistance to Clostridioides difficile infection after exposure to antibiotics or contributing to the development of chronic disorders including inflammatory bowel disease.