In Pokémon Black 2 and White 2, Rood is encountered living with Anthea, Concordia and several Grunts in the original Team Plasma's safehouse in Driftveil City. After losing in a battle with the player, he gives the player N'sZorua. Shortly afterwards, he appears on Route 6 after the player has encountered Cobalion. Later, he appears leading the members of the original Team Plasma against Ghetsis's new Team Plasma at the Giant Chasm, occupying their forces to allow the player to reach Ghetsis himself.

"It smells of the sea here. This place has the same ocean smell as where I was born…"

"Ghetsis wandered the lands of this world all over, collecting knowledge of all kinds while searching for like-minded people. From the moment we met, he understood what I desired."

"The ability to understand the minds and the needs of others… This is an ability that everyone needs to survive. My lord N is a kind and excellent person who understands the hearts of Pokémon. But, conversely, perhaps his ability to understand the hearts and feelings of people is not developed enough."

"But… Even that was part of the perfection of Ghetsis's plan. When it comes to Ghetsis, I cannot separate the truths from the lies. See this? I received it from Ghetsis, but I no longer need it. I hope you can put it to good use."

"Someday, if my lord N develops the ability to understand the feelings of people as well as Pokémon, I would like us to gather again. More than anything, I want to see N confront Ghetsis."

Pokémon Black 2 and White 2

"My guest. If you're going to come inside, I would like to see what kind of person you are, Trainer. That's right. In a Pokémon battle. Do you find this acceptable?"

Yes:"Let us begin!"

When defeated

"Ho! You fight as if you really understand your Pokémon!"

After being defeated

"I apologize for testing you. Being former members of Team Plasma, we must deal with a lot… "

"And that is? Your friend? He may join us."

Inside the house

"Let me introduce myself again. My name is Rood."

"More accurately, we're former members of Team Plasma. Because of the incident two years ago, we started taking care of the Pokémon that were separated from their Trainers as a way to atone for our misdeeds. And you are?"

"Is that so… My sincerest apologies…"

"The Pokémon you speak of is not in this place. I imagine it is still being used by Team Plasma now. Just as you say, our apologizing doesn't solve anything. But you can't move forward unless you admit you were wrong and apologize…"

"Team Plasma made Trainers like him suffer… I feel terrible about it… How foolish we were… <Player>, as you can see, I can't do anything to thank you. Actually, I have a favor to ask of you. Could you please look after this Pokémon, Zorua?"

Yes:"Oh! Thank you!"

No:"If you change your mind, please come speak to me again."

"That Zorua is one of the Pokémon that my lord N relied on as a friend during his journey."

"My lord N is a wonderful person who has the power to understand the hearts of Pokémon. But still, he has much to learn about understanding the hearts of people... I hope he will develop this skill while he travels with the legendary Pokémon to atone for the trouble he caused in Unova as the king of Team Plasma."

"Unforgivable… So the reach of Ghetsis's ambition and malice is growing ever wider and warping the lives of all it touches…"

"Did Cobalion appear in front of you merely by accident? Or to plead with you to solve a problem? Unlike Lord N, I don't have the ability to understand the minds of Pokémon. Therefore, I don't know what that Pokémon is thinking. But if you can befriend Cobalion, it will be a great asset to you on your journey."

"Aah! I will say it as many times as it takes until you understand! Ghetsis's real plan was to take over the Unova region! Liberating Pokémon was nothing more than an excuse! If anything, it would've made Pokémon suffer!"

"At times like these, those whose hearts weaken, those whose determination falters, can accomplish nothing! To save our old allies, to protect Unova, we will fight!"

"Both of you, go! No, just a moment… Hugh, was it? About the Pokémon you're looking for… In all likelihood, it is in the possession of the Shadow Triad--the dark warriors who appear silently."

"At that time, I believed we were on the side of justice. By serving my king, N, I was going to make a world without war. But I was conceited, and I couldn't see the unhappiness we were causing. That's why I can't let it happen again!"

After Team Plasma's withdrawal

"Oh! You're safe! I'm so glad! As for Team Plasma's ship, a man in a white lab coat appeared. He said that a Trainer had given him the answer he'd been seeking, and, as thanks, he would disband Team Plasma…Then he said, "Farewell! Walk a just path with Pokémon!" and he flew the ship away. So everything has been resolved. We were even able to confirm that Lord N is safe."