Background and Objectives: Obesity leads to cardiovascular diseases, diabetes, and hypertension. Sleep disorder can also cause obesity and overweight through changing the levels of neuropeptides, such as ghrelin and leptin as well as other mechanisms. In the present study, the effect of vitamin D supplement, was investigated on anthropometric indices in overweight or obese individuals with sleep disorder.

Methods: In this double-blinded clinical trial study, statistical population consisted of 74 overweight or obese women and men (age, 20-50 years) with sleep disorder who referred to Golestan Hospital in Ahvaz city. The mean serum level of vitamin D in the studied subjects was less than 30ng/ml. In the treatment group, 50000 units of vitamin D was taken for 8 weeks (once per week), and in the placebo group, 4 pearls were taken for 8 weeks. Plasma level of 25(OH)D3, weight, body mass index, waist circumference, waist to hip ratio, sunlight exposure period, physical activity, and 3-day food recall, were measured at the beginning of the study and 8 weeks later.

Results: Serum level of 25(OH)D3 significantly increased from 24.7ng/ml to 37.6ng/ml after 8 weeks of intervention in the treatment group (p<0.05). Waist circumference had a significantly change in the treatment group after 8 weeks of supplementation (p<0.05).