Crosses human placenta. No well-controlled human data but benzodiazepines are associated with increased risk of congenital anomalies if used in 1st trimester. chronic use of benzodiazepines throughout pregnancy is associated with neonatalwithdrawal and if used in last weeks of pregnancy they can cause neonatalcns depression.

Breast Feeding

Excreted into milk and potential to cause sedation, feeding difficulties and weight loss in nursing infants.

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