Corkwood elm
(Duboisia
myoporoides) is a shrub native to Australia and New Caledonia. It contains an alkaloid duboisine in its leaves which has similar chemical composition as hyoscyamine. J. Bancroft of Brisbane was the first to experiment and use it clinically. Like atropine, topical application causes mydriasis and cycloplegia. Unlike atropine, its effects are shorter and less irritating
to the eye.