Hooker Finlay Gillies replaces Brown in the front-row – the latter is affected by a shoulder knock – while Robbie McGowan, match-winner for the under-20s against their Italian counterparts during the shadow Six Nations earlier this year, is enlisted for White, who is troubled by a hamstring injury.

The Scots will be eager to bounce back from their opening match 17-14 defeat at the hands of Samoa, whereas England opened with a 43-0 success against hosts Japan.

London Scot, Ryan Wilson, who was involved in the training match against Ireland prior to departure for Japan, will start in the Scots’ back-row, while on the bench Grant Shiells and Steven Aitken are both called up.