Rare Disease Day was established in 2008 by the European Organization for Rare Diseases (EURORDIS) to raise awareness of rare diseases and improve access to treatment for patients and their families. It is held on the last day of February.

PHA Europe is part of the rare disease online social network called "Rare Connect", set up by the European Organization for Rare Diseases (EURORDIS) in 2009, to foster the sharing of experiences and increase access to quality information among rare disease communities.