December 2018 Briefing - Pathology

Here are what the editors at HealthDay consider to be the most important developments in Pathology for December 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Three Novel Loci Associated With Polycystic Ovary Syndrome ID'd

MONDAY, Dec. 31, 2018 (HealthDay News) -- Three novel loci have been identified for polycystic ovary syndrome (PCOS), according to research published online Dec. 19 in PLOS Genetics.

MONDAY, Dec. 31, 2018 (HealthDay News) -- For average-risk patients, a negative colonoscopy result is associated with a long-term reduction in the risk for colorectal cancer and related deaths, according to a study published online Dec. 17 in JAMA Internal Medicine.

FRIDAY, Dec. 28, 2018 (HealthDay News) -- Women with prior false-positive screening results have an increased risk for screen-detected and interval breast cancer for more than 10 years, according to a study published online Dec. 18 in the British Journal of Cancer.

THURSDAY, Dec. 27, 2018 (HealthDay News) -- Recipients of a lung transplant, especially a single lung transplant, have an elevated risk for lung cancer, particularly in the native lung, according to a study published online Dec. 18 in the American Journal of Transplantation.

THURSDAY, Dec. 27, 2018 (HealthDay News) -- Severe vitamin D deficiency is associated with an increased risk for renal hyperfiltration (RHF) in relatively healthy adults, according to a study published in the December issue of The American Journal of Clinical Nutrition.

THURSDAY, Dec. 27, 2018 (HealthDay News) -- A new quantitative personalized tool can better predict asthma development in young children than the Asthma Predictive Index (API), according to a study published online Dec. 13 in The Journal of Allergy and Clinical Immunology.

WEDNESDAY, Dec. 26, 2018 (HealthDay News) -- Genes are responsible for approximately one in 10 cases of chronic kidney disease in adults, according to a study published online Dec. 26 in the New England Journal of Medicine.

WEDNESDAY, Dec. 26, 2018 (HealthDay News) -- In older adults, the risk of arterial thromboembolic events begins to increase 150 days before the date of cancer diagnosis and peaks 30 days before, according to a study published online Dec. 21 in Blood.

WEDNESDAY, Dec. 26, 2018 (HealthDay News) -- Fecal occult blood test (FOBT) screening for colorectal cancer (CRC) is associated with several improved outcomes in men but not women, according to a study recently published in the British Journal of Surgery.

FRIDAY, Dec. 21, 2018 (HealthDay News) -- After infections tied to unapproved stem cell treatments sent 12 people to the hospital this past year, the U.S. Food and Drug Administration has issued a stern warning about the products.

THURSDAY, Dec. 20, 2018 (HealthDay News) -- Both restrictive and obstructive lung disease are associated with an increased risk for incident dementia and mild cognitive impairment (MCI), according to a study recently published in the American Journal of Respiratory and Critical Care Medicine.

WEDNESDAY, Dec. 19, 2018 (HealthDay News) -- For patients with multiple sclerosis (MS), food allergy is associated with a greater number of attacks and with a higher likelihood of gadolinium-enhancing lesions, according to a study published online Dec. 18 in the Journal of Neurology, Neurosurgery & Psychiatry.

TUESDAY, Dec. 18, 2018 (HealthDay News) -- From 2007 to 2017, the number of physicians excluded from Medicare and state public insurance programs increased, according to a study published online Dec. 14 in JAMA Network Open.

FRIDAY, Dec. 14, 2018 (HealthDay News) -- For patients with inflammatory bowel disease (IBD), post-inflammatory polyps (PIPs) are associated with greater severity and extent of colon inflammation and higher rates of colectomy, but not with development of colorectal neoplasia (CRN), according to a study published online Dec. 7 in Gastroenterology.

FRIDAY, Dec. 14, 2018 (HealthDay News) -- Specific locations of cerebral multiple sclerosis lesions appear to be associated with bowel incontinence, according to a study published online Dec. 11 in the Journal of Neuroimaging.

FRIDAY, Dec. 14, 2018 (HealthDay News) -- Physician mothers experience discrimination in a range of ways, which can impact the medical profession, according to a study published online Dec. 12 in The BMJ.

THURSDAY, Dec. 13, 2018 (HealthDay News) -- Medication errors in acute care that result in death occur most often in patients older than 75 years, with the most common error category being omitted medicine or ingredient, according to a study published online Nov. 22 in Research in Social and Administrative Pharmacy.

WEDNESDAY, Dec. 12, 2018 (HealthDay News) -- Enrollment for health insurance under the Affordable Care Act is down with just days left to sign up, according to the U.S. Centers for Medicare & Medicaid Services.

WEDNESDAY, Dec. 12, 2018 (HealthDay News) -- About 17 percent of patients with diabetes report experiencing hypoglycemia when fasting for lab tests, according to a study recently published in the International Journal of Endocrinology.

TUESDAY, Dec. 11, 2018 (HealthDay News) -- Policies for paid childbearing or family leave for residents are lacking at top-ranking medical schools and may be exacerbated by lack of direction from specialty boards, according to two research letters published in the Dec. 11 issue of the Journal of the American Medical Association.

TUESDAY, Dec. 11, 2018 (HealthDay News) -- After implementation of the Liaison Committee on Medical Education (LCME) diversity accreditation standards, U.S. medical schools saw increasing percentages of female, black, and Hispanic matriculants, according to a research letter published in the Dec. 4 issue of the Journal of the American Medical Association.

MONDAY, Dec. 10, 2018 (HealthDay News) -- Stress related to use of health information technology (HIT) is common and predictive of burnout among physicians, according to a study published online Dec. 5 in the Journal of the American Medical Informatics Association.

FRIDAY, Dec. 7, 2018 (HealthDay News) -- Women who have participated in mammography screening have a lower risk for dying from breast cancer within 10 and 20 years after diagnosis, according to a study recently published in Cancer.

THURSDAY, Dec. 6, 2018 (HealthDay News) -- Many patients with three or more adenomas or any adenoma with villous/tubulovillous features do not receive a subsequent colonoscopy within 3.5 years, according to a study published online Nov. 20 in Cancer Epidemiology, Biomarkers & Prevention.

THURSDAY, Dec. 6, 2018 (HealthDay News) -- An app that detects color and metadata from fingernails can identify hemoglobin levels in the blood, according to research published online Dec. 4 in Nature Communications.

THURSDAY, Dec. 6, 2018 (HealthDay News) -- Medical science has made tremendous advances in personalized medicine. However, the American public is still struggling to understand the implications of these targeted treatments, a new HealthDay/Harris Poll has revealed.

THURSDAY, Dec. 6, 2018 (HealthDay News) -- A point-of-care (POC) polymerase chain reaction test (Atlas io) has high sensitivity and specificity for Chlamydia trachomatis (CT), according to a study published in the November issue of Sexually Transmitted Diseases.

WEDNESDAY, Dec. 5, 2018 (HealthDay News) -- Only 15.4 percent of physicians work in practices that use telemedicine for a wide spectrum of patient interactions, with larger practice size being an important correlate of telemedicine use, according to a study published in the December issue of Health Affairs.

TUESDAY, Dec. 4, 2018 (HealthDay News) -- The U.S. Department of Health and Human Services has developed a draft strategy to reduce the health information technology (IT) burden, and the strategy is open for public comment through Jan. 28, 2019.

TUESDAY, Dec. 4, 2018 (HealthDay News) -- Exposure to certain endocrine-disrupting chemicals may impact the timing of puberty in children, according to a study published online Dec. 4 in Human Reproduction.

TUESDAY, Dec. 4, 2018 (HealthDay News) -- Noninvasive diagnostic imaging using machine-learning analysis of nanoresolution images of cell surfaces can detect bladder cancer with high diagnostic accuracy, according to research published online Dec. 3 in the Proceedings of the National Academy of Sciences.

TUESDAY, Dec. 4, 2018 (HealthDay News) -- There is no correlation between urate and blood pressure (BP) in mice or among patients with early Parkinson's disease (PD), according to a study published in the November issue of EBioMedicine.