AP1S3

(redirected from AP-1 complex subunit sigma-3)

AP1S3

A gene on chromosome 2q36.1 that encodes a subunit of the trans-Golgi network clathrin-associated protein complex AP-1, which is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. The vesicles are involved in protein sorting in the late-Golgi/trans-Golgi network and/or endosomes; the AP complexes recruit clathrin to membranes and recognise sorting signals within the cytosolic tails of transmembrane cargo molecules.

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