New Drug Discovered to Curb Antibiotic Resistance

A team of researchers belonging from the Virginia Institute of Technology has successfully discovered a new group of antibiotics that will help relief people who are affected by antibiotic resistance.

The antibiotic discovered will target the bacteria called Staphylococcus aureus (staph) and Staphylococcus aureus (MRSA), which is the antibiotic-resistant strain and commonly referred to as methicillin-resistant.

The new antibiotic discovered, unlike the already available antibiotics in the market shows will contain a silvery-white transition metal called iridium.

The novel transition metal complexes will not easily breakdown, which is key aspect in the delivery of antibiotics to the location in the human body where they need to fight infections.

Further investigations conducted by the researchers revealed that the metal compounds present in the antibiotics are non-toxic, hence cause no harm to animals or animal cells. Therefore, the antibiotics are rather safe to be administered in humans.

Joseph Merola, a professor of chemistry and also a member of the team of researchers said that until recently their investigations showed that the compounds they are dealing with are safer compared to other compounds which are obtained from transition metals.

The team of researchers also showed that the antibiotics they were researching on can effectively kill bacteria without restraining the mammalian cells.

Test conducted on a type of the antibiotics on mice showed the presence of no-toxicity hence, had no ill effects.

Joseph Falkinham, Professor of Biology and also a member of the team of the researcher said that they are still at the initial stage of the development and testing of the antibiotics, however so far the preliminary results of the test conducted showed that the new group of antibiotics are safe and effective.

The paper discussing their therapeutic research was published recently in the journal of Medicinal Chemistry Communications.

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