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We are incredibly excited to announce our next special guest for this year’s Disrupt SF. On top of directing the most popular TV show on the planet, House, Greg Yaitanes is an early investor in Twitter, Square, and Pinterest. Yaitanes made waves in Hollywood, leveraging cutting edge applications and applying lean startup principles to revolutionize television production. He is easily one of the most disruptive, tech-savvy minds in entertainment.

For instance, he sparked a cottage industry of light-weight professional cameras after using a simple SLR to record a season finale of House. Now, with a new show at HBO/Cinemax, he’s on a mission to prove that technology can make high-quality televsion cost-effective enough to compete with the current cultural waste-land of cheap reality-show TV. From using Google maps to remotely scout shoot locations to replacing DVDs with an iPad app, iAnnotate, Yaitanes has plugged himself into the most successful startups to gain an early vantage of upcoming tech.

As economic distance between LA and Silicon Valley shrink, Yaitanes brings a seasoned eye to see how our battlefield competitors might disrupt entertainment.

An Emmy Award-winning television director for top shows including Lost, Heroes, Grey’s Anatomy and House, Yaitanes was an early angel investor in Twitter, Square, Pinterest and Foursquare, among others.

But Yaitanes is better known for his day job as showrunner for Alan Ball’s upcoming show Banshee, which is slated to premiere on Cinemax in 2013.