1. Patch your hosts file for blocking Ads
(please think before doing this; many developers are supported through this way)

Code:

You can use AdFree application for this or changing manually your hosts file.
Here are some databases:
http://www.mvps.org/winhelp2002/hosts.txt
http://pgl.yoyo.org/adservers/serverlist.php?showintro=0;hostformat=hosts

2. Use CyanogenMOD's APN list file - it's one of the most complete.

Code:

It's located in /system/etc/apns-conf.xml

3. Use UOT kitchen for basic theming on your device.

Code:

http://uot.dakra.lt/

4. Use Google's dns servers

Code:

Create an empty file, name it resolv.conf and put there these 2 lines:
nameserver 8.8.8.8
nameserver 8.8.4.4
Save to /system/etc/.

5. Update Superuser and su binary to latest version (3.0 beta)

Code:

http://goo-inside.me/superuser/

7. Do not use task killers.

Alright, I think this is it for now.
If you have any other tweaks or better values, you can comment below and I'll include them.