We read with interest the cases described by Yadla et al in their article entitled "Neuro-toxicity due to cefepime in patients on main­tenance hemodialysis." [1] There have been mul­tiple reports of neurological symptoms secon­dary to cephalosporins in general and to cefe-pime in particular. [2],[3],[4] Interestingly, both the patients reported showed signs of myoclonus and aphasia, which may be signs of non-con­vulsive status epilepticus. [5] The one study that could have easily diagnosed this entity (EEG) was not performed in the two cases. [6] Cefepime has been reported to cause non-convulsive status epilepticus. [2],[3],[4],[7] The doses given were also not clearly mentioned as higher than usal doses have been associated with more neuro­logical effects. [7] There is a high possibility that the two patients may have had non-convulsive status epilepticus which is easily diagnosed with a routine EEG and easily terminated with benzodiazapines along with hemodialysis.