Previous GeneCards Identifiers for RN7SKP294 Gene

Summaries for RN7SKP294 Gene

GeneCards Summary for RN7SKP294 Gene

RN7SKP294 (RNA, 7SK Small Nuclear Pseudogene 294) is a Pseudogene, and is affiliated with the 7SK RNA class.

fRNAdb sequence ontologies for RN7SKP294 Gene
- the ORGUL
cluster for this gene includes several descriptions:

snRNA: A small nuclear RNA molecule involved in pre-mRNA splicing and processing.

7SK RNA: 7SK was discovered as an abundant small nuclear RNA in the mid-70s but a possible function has only recently been suggested [1]. Two independent studies have found that 7SK RNA binds the CDK9/cyclin T complex (known as elongation factor P-TEFb). P-TEFb activates transcription by phosphorylating the C-terminal domain of RNA polymerase II. This process is negatively regulated by the 7SK RNP. The secondary structure of 7SK RNA shown here was proposed by Wasserman and Steitz on the basis of chemical modification and enzymatic cleavage experiments [2]. This family contains a number of annotated pseudogenes and 7SK derived repeats. The threshold is artificially high to minimise the pseudogene count.

No data available for
Paralogs
for RN7SKP294 Gene

Variants for RN7SKP294 Gene

Additional Variant Information for RN7SKP294 Gene

No data available for
Polymorphic Variants from UniProtKB/Swiss-Prot ,
Sequence variations from dbSNP and Humsavar ,
Structural Variations from Database of Genomic Variants (DGV) and
Variation tolerance
for RN7SKP294 Gene

Disorders for RN7SKP294 Gene

No disorders were found for RN7SKP294 Gene.

No data available for
MalaCards ,
UniProtKB/Swiss-Prot ,
Genatlas and
External Links
for RN7SKP294 Gene