Coronavirus: First UK death as number of cases surges into triple figures

The first UK patient to die after testing positive for coronavirus had underlying health conditions as the number of diagnosed cases hit three figures.

The Health Secretary says the government is working "tirelessly to protect the public" from coronavirus after the UK recorded its first death.

The Royal Berkshire NHS Trust said the older patient, reported to be a woman in her 70s, had been "in and out of hospital" for other reasons but was admitted on Wednesday evening to hospital in Reading and tested positive.

It came during a day of several key developments, with the number of UK cases of Covid-19 surging to 116 - more than double the total 48 hours earlier - and Downing Street warning it was "highly likely" the virus would spread "in a significant way".

Meanwhile, more than 140 British nationals are stranded on a cruise ship after a former passenger died from coronavirus and several people on board fell ill.

The Grand Princess, which carries more than 3,500 people, remains at sea off the coast of California.

Covid-19 test kits are being flown out to the ship and will be analysed at a laboratory in San Francisco.

In the UK Health chiefs said people diagnosed with coronavirus who show only "very minimal" symptoms should self-isolate at home rather than in a hospital, while new advice was issued to travellers returning from Italy, which has become the epicentre of the outbreak in Europe.

Following the news of the UK death, Prime Minister Boris Johnson offered his sympathy to the family of the patient, while England's chief medical officer, Professor Chris Whitty, said he was "very sorry" to report the news.

He added: "We believe they contracted the virus in the UK and contact tracing is already underway."

Last week, a British tourist who had been on board the Diamond Princess cruise ship, which was quarantined in Japan, became the first UK citizen to die from the virus.

At a press conference on Thursday evening, Prof Whitty revealed that 18 people have so far recovered from coronavirus in the UK and 45 people are being treated at home.

"We have moved to a situation where people have very minimal symptoms and we think they are clinically safe and they are able to self-isolate, we think it is actually safer for them as well as more pleasant if they can self-isolate in their own homes," he said.

He had earlier warned that critical care beds in the NHS could come under intense pressure during a coronavirus epidemic, and told MPs the UK had mainly moved to the delay stage of tackling the virus, which could include measures such as school closures, encouraging greater home working, and reducing the number of large-scale gatherings.

But the PM stressed it was important not to "fire your shots too early" in escalating measures to tackle the illness.

"In something like this, what the scientists say is you've got a range of things that you can do to arrest or check the spread of a disease," he said.

"But you can't fire your shots too early, it's all about the timing and the progression."

He added: "The situation is pretty much as it has been in the sense that we are still in the contain phase, though now our scientists and medical advisers are making preparations for the delay phase."

He added that halting flights to the UK would also make it "much harder" to get medicines into the country because they are produced abroad.

Meanwhile, Government advice was updated to urge people who have returned to the UK in the past fortnight from any part of Italy - rather than just the northern regions - to call 111 or self-isolate if they feel unwell.

Those who have returned from "lockdown" areas in northern Italy in the past 14 days are advised to self-isolate regardless of whether they have symptoms.

A total of 25 new cases in England were announced on Thursday - 17 of whom had recently travelled from countries or clusters already under investigation, and eight of whom contracted the virus in the UK.

One more case was confirmed in Wales, while three more were reported in Scotland.

Half of all coronavirus cases in the UK are most likely to occur in just a three-week period, with 95% of them over a nine-week period, England's chief medical officer Chris Whitty said.

Prof Whitty said he had a "reasonably high degree of confidence" that 1% is at the "upper limit" of the mortality rate for coronavirus, although Wuhan in China, which has a weaker health system, had seen an 8% to 9% mortality rate for those aged 80 and over.

Elderly people should not self-isolate yet, he added, and neither should those with conditions such as asthma, saying there was no evidence of "deep harm" in children with asthma.

He said pregnant women should not start worrying about coronavirus but advised any smokers to stop.