Previous GeneCards Identifiers for POU2F3 Gene

Summaries for POU2F3 Gene

Entrez Gene Summary for POU2F3 Gene

This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

GeneCards Summary for POU2F3 Gene

POU2F3 (POU Class 2 Homeobox 3) is a Protein Coding gene.
Diseases associated with POU2F3 include coronary thrombosis.
Among its related pathways are Influenza A.
GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and protein dimerization activity.
An important paralog of this gene is POU6F1.