Rep. Kathleen Rice on Wednesday became the first House Democrat to call on Rep. John Conyers of Michigan to ­resign following accusations of sexual misconduct and his admission that he secretly settled a complaint with at least one woman.

“I’ve reviewed the allegations against him and they’re as credible as they are repulsive,” the Nassau County congresswoman said in a statement.

“The women who reported this behavior suffered serious professional repercussions for doing so, which is exactly why so many victims of sexual ­harassment and assault decide not to step forward.”

Earlier in the day, Queens Rep. Gregory Meeks said Conyers should definitely step aside as the top Democrat on the House Judiciary Committee while the House Ethics Committee investigates the allegations.

“I think that he needs to step down and a person should be put up on a temporary or acting basis pending the outcome of the Ethics Committee,” Meeks told The Post.

“John Conyers is an icon. He’s made America clearly a better place through the fights that he’s done through the civil-rights movement and the fights he’s had in Congress. And I think that I will always look at him in that regard. But that does not mean when you have allegations that they should not be looked into.”

Conyers, the House’s senior rep, and Meeks are members of the Congressional Black Caucus.

The Ethics Committee has opened an investigation into ­allegations that Conyers, 88, quietly settled a wrongful-dismissal complaint in 2015 after he allegedly sexually harassed a staffer, BuzzFeed News reported Tuesday.

Conyers, who was first elected in 1965, denied the allegations.

But later Tuesday, a new allegation against him surfaced from a former staffer who said she, too, was sexually harassed.