A Randomized, Phase II Trial of TNFerade Biologic with 5-FU and Radiation Therapy for FirstLine
Treatment of Unresectable Locally Advanced Pancreatic Cancer
The goal of this study is to assess the safety ofTNFerade biologic when administered
concurrently with 5-FU and radiation therapy as first-line treatment of unrcsectable locally
advanced pancreatic caneer. In addition, to determine the dose to be used for evaluation in the
randomized study phase.

The purpose of this study is to assess the use, usefulness, and acceptability of a website
designed to collect paticnt-reported outcomes from canccr outpatients and link the data
with the electronic medical record.

A Clinical Trial Comparing Preoperative Radiation Therapy and Capecitabinc with or without
Oxaliplatin with Preoperative Racliation Therapy and Continuous Intravenous Infusion of 5-
Fluorouracil with or without Oxaliplatin in the Treatment of Patients with Operable Carcinoma
of the Rectum

NSABP

Co-Investigator

8.

2006

2008

A Phase II Trial ofNeoadjuvant Chemotherapy and Local Excision for uT2uNO Rectal Cancer
The goal of this study is to dctermine the rate of disease-free survival at 3 years in ultrasoundstaged
uT2uNO rectal cancer patients treated with CRT followed by LE.

ACOSOG

Co-Investigator

9.

2005

2008

To prospectively collect serum and peripheral blood lymphocyte samples from subjects with
pancreatic and peri-ampullary cancer, pancreatitis or other non-malignant pancreatic conditions,
from healthy, at-risk volunteers and hom healthy, no-risk volunteers, in order to identify novel
targets for therapeutic interventions and response to treatments.

Pancreatic Cancer Serum and Peripheral Blood Lymphoeyte Repository

Co-Investigator

10.

2007

Longitudinal Cohort Study of Quality of Life and Transitoriness in Patients with
Pancreatic Cancer: