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Researchers found that participants investing in this drug for a year, lost weight within four weeks and have kept the extra weight off through the entire 56 weeks in the study. Contrave can be a combination in the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs which can be made up of many active ingredient, which can make them more efficient and safer.

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Seizures are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug can also raise blood pressure levels and heart rate, and must not be used in individuals with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise hypertension and pulse rate and must stop used in patients with uncontrolled high blood pressure level, along with by you aren't heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients having a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical professionals and patients for the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stop smoking.

The most common side effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.