Breakfast show host Andrew O'Keefe stood up for thousands of women who suffer in silence when he took to the stand calling for an end to domestic violence.

The popular television personality, 42, put his name, once again, to the White Ribbon Night campaign, the Foundation's September push to raise awareness, when he addressed an audience at The Grounds in Sydney on Friday.

The co-anchor of Weekend Sunrise, who is married with three children, revealed one woman on average is killed every week by a current or former partner in Australia.

Speaking up for silent sufferers: Andrew O'Keefe takes a stand against domestic violence at the White Ribbon Night event at The Grounds in Sydney on Friday

Earlier in the week, he told Daily Mail Australia he had no idea a close member of his family had suffered an abusive relationship at the hands of her partner.

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Preferring not to reveal the identity of woman to protect her privacy, he said he deeply regrets not intervening when he suspected something wasn't right.

'She was in a relationship that I guess we all knew was "turbulent",' he candidly confessed.

Doing his bit: The married father of three Andrew poses with Libby Davis (CEO of White Ribbon) at the annual affair

'It was a rocky relationship but we didn't inquire about the extent of that turbulence,' he said adding: 'It was only after it ended that we came to realise that she had actually been suffereing from physical and psychological and emotional abuse for the years that she was in it.'

He went on: 'It affected her so profoundly that I think that 10 years later she still hasn't gotten over it and it robbed her of her self-worth.'

As chairman and founding member of the organisation, garrulous Andrew wishes he had reached out and approached the issue differently.

All white on the night: The TV star, a former chairman of the White Ribbon Foundation, is pictured with a friend at a previous function for the organisation that fights to prevent violence against women

'Had I known what I know now about the issue, I would have taken a very, very different approach to her and her relationship,'he said.

'I would have asked what was really going on, I would have insisted on getting that help for her and supporting her to leave the relationship.'

He now says he encourages others to have a 'quiet conversation' if they suspect someone is in an abusive relationship, stressing the importance of reaching out to victims of ongoing abuse who often feel isolated and alone.

White Ribbon fans: From left, Andrew, Libby Davis (CEO of White Ribbon), and Dan Gregory, an ambassador and board member of the foundation, show their support for the cause

The equation isn't one sided, however, and the Deal Or No Deal host believes there needs to be a systemic change in the way men treat and view women, saying men have a responsibility to approach friends who they feel may be abusive towards their partners.

'If we have mates who we think are mistreating their partners it's our duty as friends to ask what's going on. Ask if everything is OK, or do you need help?' he said.