This Webinar will focus on the entire process of writing a clinical science grant, starting with a conceptual idea.

Peter Reese - Biography:

Peter Reese, MD, MSCE is a transplant nephrologist and epidemiologist. He is Associate Professor of Medicine (effective July 1 2017) at the University of Pennsylvania Perelman School of Medicine. His research focuses on: a) developing effective strategies to increase access to kidney transplantation, b) improving the process of selecting and caring for living kidney donors, c) determining outcomes of health policies on vulnerable populations with renal disease, including the elderly, and d) testing strategies to improve important health behaviors such as medication adherence. He chairs the Ethics Committee for the United Network for Organ Sharing (UNOS), which oversees organ allocation and transplant regulation in the US, and is an Associate Editor for the American Journal of Kidney Diseases. He is Co-Principal Investigator for the THINKER study, a pilot trial of kidney transplantation of hepatitis C positive kidneys into hepatitis C negative recipients (Clinicaltrials.gov: NCT02743897). His research funding has included grants from the NIH, the American Society of Transplantation, the American Society of Nephrology, and the Greenwall Foundation.

Matthew Levine - Biography:

Matthew Levine was raised in Houston, Texas. He attended college at Brown University and then the Medical Scientist Training Program for a combined MD and PhD at Yale University. While there, he completed his PhD dissertation in immunobiology in the laboratory of Charles Janeway Jr., with work focusing on the discovery of positive selection events in the peripheral development of B cells. He then went on to complete general surgery residency at the Massachusetts General Hospital and a fellowship in abdominal organ transplantation at the University of California, San Francisco. He joined the faculty at the University of Pennsylvania in March, 2009 in the division of transplant surgery performing renal, liver and pancreas transplants in adults and children. He is the surgical director of the CHOP renal transplant program. He is a member of the ASTS, AST, AASLD, and TTS, and serves as chair of the CME committee of the ASTS. He serves on the basic science committee of the Society of University Surgeons and is a Fellow of the American College of Surgeons. He serves on the editorial boards of the American Journal of Transplantation and Liver Transplantation.

His scientific work focuses on two broad areas. The first is the role that histone/protein acetylation and de-acetylation plays in the tolerance of end organ ischemic injury – predominantly kidney and liver. This work has been facilitated several grants from NIH/NIDDK with the work performed in collaboration with the laboratory of Wayne Hancock at the Children’s Hospital of Philadelphia. He has an additional focus on the impact of hormone manipulation on ischemic injury. The second broad aspect of scientific inquiry has focused on vascularized composite tissue allotransplantation models in mice with a focus on tolerance induction. This work has involved multiple collaborators and is funded by multiple grants from the Department of Defense. Overall, his focus in on scientific inquiry with significant translatable potential in human transplantation.