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Comedian Jimmy Pardo is holding his third annual Pardcast-a-thon, delivering comedy from 6 p.m. tonight until 6 a.m. Saturday morning. It takes place at Los Angeles's Acme Comedy Theater and streams live online.

The cause behind it is to raise money for Smile Train, a charity which pays for surgery for children with cleft lip and palate in developing countries.

Over 20 guests are planned, though most are saved as surprises. So far, Sarah Silverman, Andy Richter, Greg Behrendt, singer/food show host Lisa Loeb and Star Trek's Walter Koenig have been announced for the marathon. Guests in past year's have included Jon Hamm from "Mad Men," Conan O'Brien, musician Aimee Mann and more.

Pardo is Conan O'Brien's warmup man, doing comedy to hype the crowd up before Conan's late night talk show is taped every day. He hosts Conan Web series the Pardo Patrol, interviewing Conan's guests backstage. He also hosts the Never Not Funny podcast, a unique piece of the podcast ecosystem because, while there is a free version offered, the full shows actually require a paid subscription.

The comedy marathon raised $26,000 last year; they're hoping to beat that this year with a goal of $27,000. You can click here to donate. The surgery costs $250 and takes about 15 minutes each.

Previously in Without A Net

Looking below the radar of pop culture in L.A. and beyond. We bring you what's next, what's trending, what people are talking about and more. Follow lead Without A Net blogger Mike Roe at @MikeRoe on Twitter.