Neuronal migration and axonal guidance

Dr. Yip's group was interested in neuronal proliferation, migration and axon guidance. Their research on the chick and mouse sympathetic system was aimed at determining: 1) whether the specification of preganglionic neurons is under genetic or epigenetic control, 2) the pathway and guidance cues in the migration of preganglionic neurons, and 3) whether the projection of preganglionic axons toward their target area is guided by chemoattractant molecules.