This is known as the _____ theory of dreams.

9) (free full text)Trends Biochem Sci. 2001 Jun;26(6):390-7.The mitochondrial apoptosome: a killer unleashed by the cytochrome seas. Adrain C1, Martin SJ. Molecular Cell Biology Laboratory, Dept of Genetics, The Smurfit Institute, Trinity College, Dublin 2, Ireland.The caspase family of cysteine proteases have emerged as central regulators of apoptosis. Diverse cellular stresses trigger caspase activation by promoting release of mitochondrial components, including cytochrome c, into the cytoplasm. In turn, cytochrome c promotes the assembly of a caspase-activating complex termed the apoptosome. In this article, the and its role in life and death decisions of cells are discussed.

Freud’s theory about the nature of dreams can logically follow.

The Activation-Synthesis Theory of Dreams

The pharmacological importance of cannabinoids has been in study for several years. Cannabinoids comprise of (a) the active compounds of the Cannabis sativa plant, (b) endogenous as well as (c) synthetic cannabinoids. Though cannabinoids are clinicall`y used for anti-palliative effects, recent studies open a promising possibility as anti-cancer agents. They have been shown to possess anti-proliferative and anti-angiogenic effects in vitro as well as in vivo in different cancer models. Cannabinoids regulate key cell signaling pathways that are involved in cell survival, invasion, angiogenesis, metastasis, etc. There is more focus on CB1 and CB2, the two cannabinoid receptors which are activated by most of the cannabinoids. In this review article, we will focus on a broad range of cannabinoids, their receptor dependent and receptor independent functional roles against various cancer types with respect to growth, metastasis, energy metabolism, immune environment, stemness and future perspectives in exploring new possible therapeutic opportunities.

Latent Content: The Hidden Meaning of Your Dreams

One of the important aspects of an effective anti-tumor drug is its ability to inhibit proliferation of cancer cells. Cancer cells proliferate rapidly in uncontrolled manner. Also, these cells escape death mechanism which a normal cell undergoes like apoptosis. Apoptosis is a kind of programmed cell death (PCD) mechanism which involves activation of caspase dependent and independent pathways [39]. Cannabinoids have been proved to be anti-proliferative and apoptotic drugs. This section comprises of the detailed role of cannabinoids in modulation of tumor proliferation, cell cycle and apoptosis in various cancer types.

Name Stars Updated; A New Neurocognitive Theory of Dreams

The Activation Synthesis Dream Theory is an attempt to explain why it is that humans dream. It is a question that scientists, philosophers, and clergy have attempted to solve for thousands of years. Under this theory, dreams are an attempt by the brain to make sense of neural activity which occurs while people sleep.

according to activation-synthesis theory dreams

Further studies were done by Massi pubished in a 2006 , further elucidating the molecular pathways leading to apoptosis by CBD in her human glioma cell model. She demonstrated that Mitochondrial release of cytochrome C, Caspase activation and reactive oxygen species (ROS) induction triggered the apoptosis in the CBD treated human glioma cells. CBD treated normal glioma cells were left unharmed, again showing selectivity.

Posts about activation-synthesis hypothesis written by Ryan Bowen

Early studies in 2003 by at Hebrew University in Jerusalem showed cannabidiol (CBD) induced apoptosis via caspase activation in human leukemia cell culture (HL-60 cells). Giving the leukemia cells a short burst of radiation therapy prior to CBD enhanced the effect, attaining a 90-85% cell death rate. Normal white cells were left unharmed.

Activation-Synthesis Theory - Hobson and McCarley …

Above Diagram shows the intrinsic mitochondrial pathway which involves activation of caspase enzymes cascades, the final step in programmed cell death. Upon trigger event such as CBD activation of the ) (17) , the Mitochondrial outer membrane becomes permeable. This is a point-of-no-return in the mitochondrial apoptotic pathway and induces Mitochondrial release of cytochrome C to the cytosol which then initiates cell death in a caspase-dependent manner. In sddition to proteolytic degradation of cell organelles, proteolytic enzymes are released to the nucleus which induce DNA fragmentation.

Activation- Synthesis The interpretation of dreams developed by Dr

In conclusion, our data indicate that cannabidiol, and possibly Cannabis extracts enriched in this natural cannabinoid, represent a promising nonpsychoactive antineoplastic strategy. In particular, for a highly malignant human breast carcinoma cell line, we have shown here that cannabidiol and a cannabidiol-rich extract counteract cell growth both in vivo and in vitro as well as tumor metastasis in vivo. Cannabidiol exerts its effects on these cells through a combination of mechanisms that include either direct or indirect activation of CB2 and TRPV1 receptors and induction of oxidative stress, all contributing to induce apoptosis.

Activation Synthesis Dream Theory Explained | HRFnd

The total synthesis of (+)-lithospermic acid is reported, which exploits two successive C−H activation reactions as key steps. Rh-catalyzed carbene C−H insertion reaction utilizing Davies’s catalyst was used to forge dihydrobenzofuran core, and a late-stage intermolecular C−H olefination coupled the olefin unit with the dihydrobenzofuran core to construct the molecule in a highly convergent manner.