First published December 20, 2017, DOI: https://doi.org/10.1212/WNL.0000000000004835

Sun-Young Oh

From the Department of Neurology (S.-Y.O., H.-J.S.), Chonbuk National University School of Medicine; Research Institute of Clinical Medicine (S.-Y.O., H.-J.S.), Chonbuk National University–Biomedical Research Institute, Chonbuk National University Hospital, Jeonju, Korea; Department of Neurology (S.-Y.O., M.E., P.z.E., M.D.) and German Center for Vertigo and Balance Disorders (R.B., M.D.), University Hospital, and Graduate School of Systemic Neuroscience (R.B., M.E., P.z.E., M.D.), Ludwig-Maximilians-University; Munich Cluster for Systems Neurology (SyNergy) (M.D.), Germany; and Department of Neurology (J.-S.K.), Seoul National University School of Medicine, Korea.

From the Department of Neurology (S.-Y.O., H.-J.S.), Chonbuk National University School of Medicine; Research Institute of Clinical Medicine (S.-Y.O., H.-J.S.), Chonbuk National University–Biomedical Research Institute, Chonbuk National University Hospital, Jeonju, Korea; Department of Neurology (S.-Y.O., M.E., P.z.E., M.D.) and German Center for Vertigo and Balance Disorders (R.B., M.D.), University Hospital, and Graduate School of Systemic Neuroscience (R.B., M.E., P.z.E., M.D.), Ludwig-Maximilians-University; Munich Cluster for Systems Neurology (SyNergy) (M.D.), Germany; and Department of Neurology (J.-S.K.), Seoul National University School of Medicine, Korea.

From the Department of Neurology (S.-Y.O., H.-J.S.), Chonbuk National University School of Medicine; Research Institute of Clinical Medicine (S.-Y.O., H.-J.S.), Chonbuk National University–Biomedical Research Institute, Chonbuk National University Hospital, Jeonju, Korea; Department of Neurology (S.-Y.O., M.E., P.z.E., M.D.) and German Center for Vertigo and Balance Disorders (R.B., M.D.), University Hospital, and Graduate School of Systemic Neuroscience (R.B., M.E., P.z.E., M.D.), Ludwig-Maximilians-University; Munich Cluster for Systems Neurology (SyNergy) (M.D.), Germany; and Department of Neurology (J.-S.K.), Seoul National University School of Medicine, Korea.

From the Department of Neurology (S.-Y.O., H.-J.S.), Chonbuk National University School of Medicine; Research Institute of Clinical Medicine (S.-Y.O., H.-J.S.), Chonbuk National University–Biomedical Research Institute, Chonbuk National University Hospital, Jeonju, Korea; Department of Neurology (S.-Y.O., M.E., P.z.E., M.D.) and German Center for Vertigo and Balance Disorders (R.B., M.D.), University Hospital, and Graduate School of Systemic Neuroscience (R.B., M.E., P.z.E., M.D.), Ludwig-Maximilians-University; Munich Cluster for Systems Neurology (SyNergy) (M.D.), Germany; and Department of Neurology (J.-S.K.), Seoul National University School of Medicine, Korea.

From the Department of Neurology (S.-Y.O., H.-J.S.), Chonbuk National University School of Medicine; Research Institute of Clinical Medicine (S.-Y.O., H.-J.S.), Chonbuk National University–Biomedical Research Institute, Chonbuk National University Hospital, Jeonju, Korea; Department of Neurology (S.-Y.O., M.E., P.z.E., M.D.) and German Center for Vertigo and Balance Disorders (R.B., M.D.), University Hospital, and Graduate School of Systemic Neuroscience (R.B., M.E., P.z.E., M.D.), Ludwig-Maximilians-University; Munich Cluster for Systems Neurology (SyNergy) (M.D.), Germany; and Department of Neurology (J.-S.K.), Seoul National University School of Medicine, Korea.

From the Department of Neurology (S.-Y.O., H.-J.S.), Chonbuk National University School of Medicine; Research Institute of Clinical Medicine (S.-Y.O., H.-J.S.), Chonbuk National University–Biomedical Research Institute, Chonbuk National University Hospital, Jeonju, Korea; Department of Neurology (S.-Y.O., M.E., P.z.E., M.D.) and German Center for Vertigo and Balance Disorders (R.B., M.D.), University Hospital, and Graduate School of Systemic Neuroscience (R.B., M.E., P.z.E., M.D.), Ludwig-Maximilians-University; Munich Cluster for Systems Neurology (SyNergy) (M.D.), Germany; and Department of Neurology (J.-S.K.), Seoul National University School of Medicine, Korea.

From the Department of Neurology (S.-Y.O., H.-J.S.), Chonbuk National University School of Medicine; Research Institute of Clinical Medicine (S.-Y.O., H.-J.S.), Chonbuk National University–Biomedical Research Institute, Chonbuk National University Hospital, Jeonju, Korea; Department of Neurology (S.-Y.O., M.E., P.z.E., M.D.) and German Center for Vertigo and Balance Disorders (R.B., M.D.), University Hospital, and Graduate School of Systemic Neuroscience (R.B., M.E., P.z.E., M.D.), Ludwig-Maximilians-University; Munich Cluster for Systems Neurology (SyNergy) (M.D.), Germany; and Department of Neurology (J.-S.K.), Seoul National University School of Medicine, Korea.

Citation Manager Formats

Share

This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.

Abstract

Objective To increase clinical application of vestibular-evoked myogenic potentials (VEMPs) by reducing the testing time by evaluating whether a simultaneous recording of ocular and cervical VEMPs can be achieved without a loss in diagnostic sensitivity and specificity.

Methods Simultaneous recording of ocular and cervical VEMPs on each side during monaural stimulation, bilateral simultaneous recording of ocular VEMPs and cervical VEMPs during binaural stimulation, and conventional sequential recording of ocular and cervical VEMPs on each side using air-conducted sound (500 Hz, 5-millisecond tone burst) were compared in 40 healthy participants (HPs) and 20 patients with acute vestibular neuritis.

Results Either simultaneous recording during monaural and binaural stimulation effectively reduced the recording time by ≈55% of that for conventional sequential recordings in both the HP and patient groups. The simultaneous recording with monaural stimulation resulted in latencies and thresholds of both VEMPs and the amplitude of cervical VEMPs similar to those found during the conventional recordings but larger ocular VEMP amplitudes (156%) in both groups. In contrast, compared to the conventional recording, simultaneous recording of each VEMP during binaural stimulation showed reduced amplitudes (31%) and increased thresholds for cervical VEMPs in both groups.

Conclusions The results of simultaneous recording of cervical and ocular VEMPs during monaural stimulation were comparable to those obtained from the conventional recording while reducing the time to record both VEMPs on each side.

ClinicalTrials.gov identifier NCT03049683.

Glossary

ACS=

air-conducted sound;

cVEMP=

cervical vestibular-evoked myogenic potential;

HP=

healthy participant;

oVEMP=

ocular vestibular-evoked myogenic potential;

SCC=

semicircular canal;

VEMP=

vestibular-evoked myogenic potential;

VN=

vestibular neuritis

Footnotes

Go to Neurology.org for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the article.

Disputes & Debates: Rapid online correspondence

NOTE: All contributors' disclosures must be entered and current in our database before comments can be posted. Enter and update disclosures at http://submit.neurology.org. Exception: replies to comments concerning an article you originally authored do not require updated disclosures.

Stay timely. Submit only on articles published within the last 8 weeks.

Do not be redundant. Read any comments already posted on the article prior to submission.

200 words maximum.

5 references maximum. Reference 1 must be the article on which you are commenting.

5 authors maximum. Exception: replies can include all original authors of the article.

Submitted comments are subject to editing and editor review prior to posting.

I, the first and corresponding author, verify that I have read the contents of the PUBLISHING AGREEMENT form. *

I, the first and corresponding author, verify my disclosures and those of my co-authors are up to date at http://submit.neurology.org. *

Select only one of the three options below: *

I am an Author of this Work, and the Work was prepared on my own time - not as part of my duties as an employee.

I prepared (or cooperated in the preparation of) the Work as part of my duties as an employee, and the Work is, therefore, a "work made for hire", as defined by the United States Copyright Act of 1976, as amended.

I prepared (or participated in the preparation of) the Work as part of my official duties as an officer or employee of the United States Government.

NOTE: All contributors, besides the first/corresponding author, must complete a separate Disputes & Debates Submission Form and provide via email to the editorial office before comments can be posted.