Today your clients are requiring that their website be more than just desktop compliant but that their website also provides a rich mobile experience that is optimized for smart-phones and tables. In this talk we will outline multiple HTML 5 Mobile Frameworks which use different approaches to responsive design layouts, how to take advantage of smart-phone features like touch, swipe, css3 and animations and best practices to display content across multiple screen sizes. In particular, we will share our experiences with Sencha, 320, Bootstrap, and Up. We will roll up our sleeves an review additional javascript for sliders and methods to display the same image at different screen sizes.