The Marshall W. Nirenberg Papers

This innovative article is one of Nirenberg's most important early contributions to the coding problem. Published along
with "The Dependence of Cell-Free Protein Synthesis in E. coli Upon Naturally Occurring or Synthetic Polyribonucleotides,"
this article provides experimental evidence that an extract prepared from bacterial cells can make protein even when intact
living cells are not present. This revelation is a crucial step in the history of breaking the genetic code.

Number of Image Pages:

9 (842,397 Bytes)

Date:

1961-10 (October 1961)

Creator:

Matthaei, J. Heinrich

Nirenberg, Marshall W.

Source:

Periodical: Matthaei, J. Heinrich, and Marshall W. Nirenberg. "Characteristics and Stabilization of DNAase-Sensitive Protein Synthesis
in E. Coli Extracts." Proceedings of the National Academy of Sciences of the United States of America 47, 10 (October
1961): 1580-1588. Article. 9 Images.