Healthcare Providers: Disease Information

Cryopyrin-Associated Periodic Syndromes (CAPS) are a group of rare, inherited, autoinflammatory diseases. CAPS are made up of 3 subtypes that share some common symptoms, including rash, fever/chills, joint pain, fatigue, and eye redness/pain.

Additional Information

FCAS
FCAS may cause frequent attacks that include symptoms such as rash, fever/chills, joint pain, eye redness/pain, and fatigue. Flares are triggered by exposure to cooling temperatures. Diagnosis usually occurs shortly after birth.

MWS
MWS is characterized by recurrent rash, fever/chills, joint pain, eye redness/pain, and fatigue. Symptoms are triggered by random, unknown factors and possibly by stress, exercise, or cold. MWS is often associated with hearing loss and amyloidosis—the presence of a protein in the kidneys or other organs that can interfere with their function.