Impact of glycemic control on colonoscopy outcomes: bowel preparation and polyp detection
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Creator

Singhal, Shashideep

Alhankawi, Dhuha

Izzy, Manhal

Changela, Kinesh

Haeri, Nami Safai

Jibara, Ghalib

Anand, Sury

Shah, Sulay

Description

Background The negative eff ect of diabetes mellitus (DM) on the colonoscopy preparation has been previously established. Metabolic syndrome has been shown to increase risk for malignancy and possibly for premalignant lesions. This study aimed to investigate the impact of DM control on colonoscopy outcomes including bowel preparation and adenoma detection rate (ADR).Methods We included patients with DM who underwent colonoscopy in our hospital and had a documented glycated hemoglobin (HbA1C) within 3 months. Patients were categorized into three groups based on their HbA1C level. The clinical and endoscopic data were collected and analyzed.Results Our cohort included 352 DM patients. The mean age was 63.5 years. When patients were analyzed based on HBA1C, bowel preparation was poor in 46.7% of patients with good glycemic control, 52.1% of patients with fair control and 50% of patients with poor control. ADR was 24.3% in patients with good glycemic control, 20.2% in patients with fair glycemic control and 27.1% in patients with poor glycemic control. There was no statistically signifi cant difference in the quality of preparation or adenoma detection amongst the groups.Conclusion The degree of glycemic control did not impact the quality of bowel preparation or ADR.Keywords Adenoma detection rate, diabetes mellitus, bowel preparation, colonoscopy, glycosylated hemoglobinAnn Gastroenterol 2016; 29 (3): 332-335
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