For the average/normal user the simple answer to can you is , yes you can . Use either the "uninstaller.exe file in your programme's folder or if the programme is displayed in the "Add/Remove" section of your Control Panel or similar (according to your OS) you can also use that facility . Some clean up software have an "uninstaller" tool , but they may not be needed by you . It is likely that a few old files may get left behind , but they should not provoke a problem ; so unless they do , they can be ignored .

The other question is should you , which depends on whether you ever use the programme , whether you can update it or replace it , etc.

If you are not sure you can always rename the programme by adding a suffix such as "_old" (without the quotation marks) directly to the end of the file that the PSI is detecting :eg : myuselessprogramme.exe would become myuselessprogramme.exe_old ; neither you nor the bad guys can use it and the PSI will no longer display it as "EOL". After a while , if you find you do not need it , then you can uninstall/delete the software .

If you need further help , post back with your version of the PSI and your OS , the "EOL" programmes , their version # and their detected instance installation paths displayed in the PSI .