information aboutusing marinol capsules1

MARINOL Capsules should be taken exactly as your doctor tells you to.

Appetite Stimulation for Patients with AIDS: You will most likely start therapy by taking one 2.5 mg capsule twice daily, 1 hour before lunch and 1 hour before dinner. Your doctor may adjust your dosage after seeing how it affects you. Do not change your dose unless your doctor tells you to change it. If you are elderly or unable to tolerate this dose of MARINOL, your doctor may prescribe MARINOL to be taken 1 time each day, 1 hour before dinner or bedtime to reduce your chance of having nervous system problems.

For Nausea and Vomiting Associated with Cancer Chemotherapy: Your doctor will prescribe an appropriate dose for you. This dose may be given before and after chemotherapy for a total of 4 to 6 doses per day. MARINOL is usually taken 1 to 3 hours before your chemotherapy treatment and then every 2 to 4 hours after chemotherapy for up to 4 to 6 doses each day. If you are elderly, your doctor may prescribe MARINOL to be taken 1 to 3 hours before your chemotherapy, 1 time each day to reduce your chance of having nervous system problems.

Take your first dose of MARINOL on an empty stomach at least 30 minutes before eating. After your first dose of MARINOL, you can take MARINOL with or without food. Always take your dose at the same time with regard to meals.

If you take too much MARINOL, call your Poison Control Center at 1-800-222-1222 right away.

Important Information about Using MARINOL Capsules

MARINOL is a controlled substance which can be a target for people who abuse prescription medicines or street drugs. Keep your MARINOL in a safe place to protect it from theft.

Do not take MARINOL if you had an allergic reaction to dronabinol or sesame oil. Signs and symptoms of an allergic reaction to dronabinol include: swelling of the lips, hives, a rash over your whole body, mouth sores, skin burning, flushing, and throat tightness.

Do not drive, operate machinery, or do other dangerous activities until you know how MARINOL affects you.

If you have a history of drug or alcohol abuse, do not drink alcohol, smoke marijuana, or take other drugs that may increase your risk of drug abuse while taking MARINOL capsules.

Tell your doctor about all prescription and over-the-counter medicines, vitamins and herbal supplements you take, or have taken in the last 14 days. MARINOL and certain other medicines can affect each other, causing serious side effects.

Unless advised by your doctor, do not use MARINOL Capsules if you are pregnant or nursing.

Use and important safety information

Use1

MARINOL® (dronabinol) is a prescription medicine used in adults to treat:

Loss of appetite in people with AIDS (acquired immune deficiency syndrome) who have lost weight.

Nausea and vomiting caused by anti-cancer medicine (chemotherapy) in people whose nausea and vomiting have not improved with usual anti-nausea medicines.

MARINOL is a controlled substance, which can be a target for people who abuse prescription medicines or street drugs. Keep your MARINOL in a safe place to protect it from theft.

Important Safety Information1

Do not take MARINOL if you had an allergic reaction to dronabinol or sesame oil. Signs and symptoms of an allergic reaction to dronabinol include: swelling of the lips, hives, a rash over your whole body, mouth sores, skin burning, flushing, and throat tightness.

MARINOL can cause serious side effects, including:

Worsening of mental (psychiatric) symptoms in people who have mania, depression, or schizophrenia. Tell your doctor if you have new or worsening mood symptoms, including symptoms of mania, depression, or schizophrenia.

Seizures. MARINOL may increase your risk of seizures. Stop taking MARINOL and call your doctor and get medical help right away if you have a seizure.

Drug and alcohol abuse. You may have an increased risk of abusing MARINOL if you have a history of drug or alcohol abuse or dependence, including marijuana. Tell your doctor if you develop increased irritability, nervousness, restlessness, or want more or higher doses of MARINOL.

Nausea, vomiting, or stomach-area (abdominal) pain. Tell your doctor if you have nausea, vomiting, or abdominal pain, or if these get worse with treatment.

Before taking MARINOL, tell your doctor about all of your medical conditions, including if you:

Have or had problems with your heart, drug abuse or dependence, alcohol abuse or dependence.

Have or had mental health problems including mania, depression, or schizophrenia.

Have or had a seizure or have a medical condition that may increase your risk of seizures.

Are pregnant or plan to become pregnant. MARINOL may harm your unborn baby. Avoid use of MARINOL if you are pregnant.

Are breastfeeding or plan to breastfeed. Do not breastfeed while taking MARINOL and for 9 days after your last dose.

Tell your doctor about all prescription and over-the-counter medicines, vitamins, and herbal supplements you take or have taken in the last 14 days. MARINOL and certain other medicines can affect each other, causing serious side effects.

Do not drive, operate machinery, or do other dangerous activities until you know how MARINOL affects you. When taken with other medicines that cause dizziness, confusion, and sleepiness, MARINOL can worsen these symptoms.

The most common side effects of MARINOL include: dizziness, feeling extremely happy (euphoria), overly suspicious or feeling people want to harm you (paranoid reaction), sleepiness, abnormal thoughts, stomach-area (abdominal) pain, nausea, or vomiting.

Reference:

MARINOL [package insert]. North Chicago, IL: AbbVie Inc.

MARINOL Capsules are a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.

If you cannot afford your medication, contact www.pparx.org for assistance.

Use and important safety information

MARINOL® (dronabinol) is a prescription medicine used in adults to treat:

Loss of appetite in people with AIDS (acquired immune deficiency syndrome) who have lost weight.

Nausea and vomiting caused by anti-cancer medicine (chemotherapy) in people whose nausea and vomiting have not improved with usual anti-nausea medicines.

MARINOL is a controlled substance, which can be a target for people who abuse prescription medicines or street drugs. Keep your MARINOL in a safe place to protect it from theft.

Important Safety Information1

Do not take MARINOL if you had an allergic reaction to dronabinol or sesame oil. Signs and symptoms of an allergic reaction to dronabinol include: swelling of the lips, hives, a rash over your whole body, mouth sores, skin burning, flushing, and throat tightness.

MARINOL can cause serious side effects, including:

Worsening of mental (psychiatric) symptoms in people who have mania, depression, or schizophrenia. Tell your doctor if you have new or worsening mood symptoms, including symptoms of mania, depression, or schizophrenia.

Seizures. MARINOL may increase your risk of seizures. Stop taking MARINOL and call your doctor and get medical help right away if you have a seizure.

Drug and alcohol abuse. You may have an increased risk of abusing MARINOL if you have a history of drug or alcohol abuse or dependence, including marijuana. Tell your doctor if you develop increased irritability, nervousness, restlessness, or want more or higher doses of MARINOL.

Nausea, vomiting, or stomach-area (abdominal) pain. Tell your doctor if you have nausea, vomiting, or abdominal pain, or if these get worse with treatment.

Before taking MARINOL, tell your doctor about all of your medical conditions, including if you:

Have or had problems with your heart, drug abuse or dependence, alcohol abuse or dependence.

Have or had mental health problems including mania, depression, or schizophrenia.

Have or had a seizure or have a medical condition that may increase your risk of seizures.

Are pregnant or plan to become pregnant. MARINOL may harm your unborn baby. Avoid use of MARINOL if you are pregnant.

Are breastfeeding or plan to breastfeed. Do not breastfeed while taking MARINOL and for 9 days after your last dose.

Tell your doctor about all prescription and over-the-counter medicines, vitamins, and herbal supplements you take or have taken in the last 14 days. MARINOL and certain other medicines can affect each other, causing serious side effects.

Do not drive, operate machinery, or do other dangerous activities until you know how MARINOL affects you. When taken with other medicines that cause dizziness, confusion, and sleepiness, MARINOL can worsen these symptoms.

The most common side effects of MARINOL include: dizziness, feeling extremely happy (euphoria), overly suspicious or feeling people want to harm you (paranoid reaction), sleepiness, abnormal thoughts, stomach-area (abdominal) pain, nausea, or vomiting.

Reference:

MARINOL [package insert]. North Chicago, IL: AbbVie Inc.

SAFETY CONSIDERATIONS1

Do not take MARINOL if you have had an allergic reaction to dronabinol or sesame oil. MARINOL can cause worsening of mental (psychiatric) symptoms or problems thinking clearly. Tell your doctor if you have new or worsening mood symptoms or trouble remembering things, concentrating, have increased sleepiness, or confusion. Do not drive, operate machinery, or do other dangerous activities until you know how MARINOL affects you. MARINOL may cause changes in blood pressure. Tell your doctor if you have headaches, vision problems, dizziness, feeling lightheaded, fainting, or a fast heartbeat. Elderly people may be more sensitive to the effects of MARINOL. MARINOL may increase your risk of seizures. Stop taking MARINOL and call your doctor right away if you have a seizure. You may have an increased risk of abusing MARINOL if you have a history of drug or alcohol abuse. Tell your doctor if you develop increased irritability, nervousness, restlessness, or want more or higher doses of MARINOL. MARINOL may cause nausea, vomiting, or stomach-area (abdominal) pain. Tell your doctor if these stomach-area symptoms get worse with treatment. Tell your doctor about all prescription and over-the-counter medicines, vitamins, and herbal supplements you take. MARINOL and certain other medicines can affect each other, causing serious side effects.

You are leaving the MARINOL (dronabinol) website and connecting to a site that is not under the control of AbbVie. AbbVie is not responsible for the contents of any such site or any further links from such site. AbbVie is providing these links to you only as a convenience and the inclusion of any link does not imply the endorsement of the linked site by AbbVie. You should also be aware that the linked site may be governed by its own set of terms and conditions and privacy policy for which AbbVie has no responsibility.