As of January 2019 the IFCC has recently created a Committee on “Bone Metabolism (C-BM)”, formed by the joining of the already existing Working Groups:- Standardization of Bone Markers Assays (WG-BMA) in collaboration with IOF- Parathyroid Hormone (WG-PTH)- Vitamin D Standardization Program (WG-Vit D)

The Terms of Reference

Standardize PTH assays

Standardize or harmonize bone markers assays

Standardize vitamin D metabolites assays

Current Projects

1. PTH assays

Create liaison with International Endocrinological, Rheumatological and Nephological organizations

Define the measurand (what we need to measure for all clinical situations)

Develop a reference measurement procedure for PTH(1-84) and moieties of clinical interest

Evaluate the commutability of PTH International standard PTH 95/646 and the need to create primary reference material

Replicate the RMP in a second lab and create a network of 3-4 reference labs

Create an accuracy-based external quality assessment scheme

Constitute an appropriate and international panel of sera and plasma to establish PTH reference intervals