We provide a comprehensive analysis of the power of including top quark-polarisation information to kinematically challenging top pair resonance searches, for which ATLAS and CMS start losing sensitivity. Following the general modelling and analysis strategies pursued by the experiments, we analyse the semi-leptonic and the di-lepton channels and show that including polarisation ...

The move towards simplified models for Run II of the LHC will allow for stronger and more robust constraints on the dark sector. However there already exists a wealth of Run I data which should not be ignored in the run-up to Run II. Here we reinterpret public constraints on generic beyond-standard-model cross sections to place new constraints on a simplified model. We make use of ...

The binding and contribution of transcription factors (TF) to cell specific gene expression is often deduced from open-chromatin measurements to avoid costly TF ChIP-seq assays. Thus, it is important to develop computational methods for accurate TF binding prediction in open-chromatin regions (OCRs). Here, we report a novel segmentation-based method, TEPIC, to predict TF binding by ...

The Fortran LHAPDF library has been a long-term workhorse in particle physics, providing standardised access to parton density functions for experimental and phenomenological purposes alike, following on from the venerable PDFLIB package. During Run 1 of the LHC, however, several fundamental limitations in LHAPDF’s design have became deeply problematic, restricting the usability of ...

The ever-growing amount of data in the field of life sciences demands standardized ways of high-throughput computational analysis. This standardization requires a thorough documentation of each step in the computational analysis to enable researchers to understand and reproduce the results. However, due to the heterogeneity in software setups and the high rate of change during tool ...

Memory type 1 T helper (TH1) cells are characterized by the stable expression of interferon (IFN)-γ as well as by the epigenetic imprinting of the IFNG locus. Among innate cells, NK cells play a crucial role in the defense against cytomegalovirus (CMV) and represent the main source of IFN-γ. Recently, it was shown that memory-like features can be observed in NK cell subsets after ...