Hirsla - Landsp&#237;tali University Hospitalhttp://www.hirsla.lsh.is:80/lsh
Hirsla captures, stores, indexes, preserves, and distributes digital research material.Fri, 09 Dec 2016 00:05:33 GMT2016-12-09T00:05:33ZReporting Helicopter Emergency Medical Services in Major Incidents: A Delphi Study.http://hdl.handle.net/2336/620092
Title: Reporting Helicopter Emergency Medical Services in Major Incidents: A Delphi Study.
Authors: Fattah, Sabina; Johnsen, Anne Siri; Sollid, Stephen J M; Wisborg, Torben; Rehn, Marius; Sóti, Ákos; Truhlář, Anatolij; Krüger, Andreas J; Gunnarsson, Björn; Gryth, Dan; Ohlén, David; Fevang, Espen; Sunde, Geir Arne; Breitenmoser, Ivo; Kurola, Jouni; Nurmi, Jouni; Fredriksen, Knut; Rognås, Leif; Temesvari, Peter; Mikkelsen, Søren; Magnusson, Vidar; Voelckel, Wolfgang
Abstract: Research on helicopter emergency medical services (HEMS) in major incidents is predominately based on case descriptions reported in a heterogeneous fashion. Uniform data reported with a consensus-based template could facilitate the collection, analysis, and exchange of experiences. This type of database presently exists for major incident reporting at www.majorincidentreporting.net. This study aimed to develop a HEMS-specific major incident template.; This Delphi study included 17 prehospital critical care physicians with current or previous HEMS experience. All participants interacted through e-mail. We asked these experts to define data variables and rank which were most important to report during an immediate prehospital medical response to a major incident. Five rounds were conducted.; In the first round, the experts suggested 98 variables. After 5 rounds, 21 variables were determined by consensus. These variables were formatted in a template with 4 main categories: HEMS background information, the major incident characteristics relevant to HEMS, the HEMS response to the major incident, and the key lessons learned.; Based on opinions from European experts, we established a consensus-based template for reporting on HEMS responses to major incidents. This template will facilitate uniformity in the collection, analysis, and exchange of experience.
Description: To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files.
This article is open access.Fri, 01 Jan 2016 00:00:00 GMThttp://hdl.handle.net/2336/6200922016-01-01T00:00:00ZAssociation of bone turnover markers with volumetric bone loss, periosteal apposition, and fracture risk in older men and women: the AGES-Reykjavik longitudinal study.http://hdl.handle.net/2336/620091
Title: Association of bone turnover markers with volumetric bone loss, periosteal apposition, and fracture risk in older men and women: the AGES-Reykjavik longitudinal study.
Authors: Marques, E A; Gudnason, V; Lang, T; Sigurdsson, G; Sigurdsson, S; Aspelund, T; Siggeirsdottir, K; Launer, L; Eiriksdottir, G; Harris, T B
Abstract: Association between serum bone formation and resorption markers and cortical and trabecular bone loss and the concurrent periosteal apposition in a population-based cohort of 1069 older adults was assessed. BTM levels moderately reflect the cellular events at the endosteal and periosteal surfaces but are not associated with fracture risk.; We assessed whether circulating bone formation and resorption markers (BTM) were individual predictors for trabecular and cortical bone loss, periosteal expansion, and fracture risk in older adults aged 66 to 93 years from the AGES-Reykjavik study.; The sample for the quantitative computed tomography (QCT)-derived cortical and trabecular BMD and periosteal expansion analysis consisted of 1069 participants (474 men and 595 women) who had complete baseline (2002 to 2006) and follow-up (2007 to 2011) hip QCT scans and serum baseline BTM. During the median follow-up of 11.7 years (range 5.4-12.5), 54 (11.4 %) men and 182 (30.6 %) women sustained at least one fracture of any type.; Increase in BTM levels was associated with faster cortical and trabecular bone loss at the femoral neck and proximal femur in men and women. Higher BTM levels were positively related with periosteal expansion rate at the femoral neck in men. Markers were not associated with fracture risk.; This data corroborates the notion from few previous studies that both envelopes are metabolically active and that BTM levels may moderately reflect the cellular events at the endosteal and periosteal surfaces. However, our results do not support the routine use of BTM to assess fracture risk in older men and women. In light of these findings, further studies are justified to examine whether systemic markers of bone turnover might prove useful in monitoring skeletal remodeling events and the effects of current osteoporosis drugs at the periosteum.
Description: To access publisher's full text version of this article click on the hyperlink at the bottom of the pageThu, 01 Dec 2016 00:00:00 GMThttp://hdl.handle.net/2336/6200912016-12-01T00:00:00ZBiliary tract malignancies: a population-based study on incidence, prognosis and management of patients.http://hdl.handle.net/2336/620090
Title: Biliary tract malignancies: a population-based study on incidence, prognosis and management of patients.
Authors: Juliusson, Gunnar; Jonasson, Jon Gunnlaugur; Jonsdottir, Sara B; Garcia, Henrik G; Olafsdottir, Elinborg; Möller, Pall Helgi; Björnsson, Einar S
Abstract: Biliary tract malignancies are uncommon and few population-based studies are available.; This nationwide population-based study in Iceland included all patients diagnosed with intra- and extrahepatic cholangiocarcinoma, gallbladder and ampullary cancer from 1984 to 2012. Patients were identified through the Icelandic Cancer Registry. Clinical information was obtained from patient records.; Overall 245 patients were identified: 38 had intrahepatic cholangiocarcinoma, 66 extrahepatic cholangiocarcinoma, 73 gallbladder cancer (GBC) and 68 ampullary cancer. Overall incidence for bile tract malignancies was 1-3 per 100,000 person-years and less than 1 by sub-type. The overall bile tract malignancies in males increased from 1.3 (95% CI 0.8-1.8) to 2.5 (1.9-3.1) per 100,000 inhabitants. The incidence of GBC among females decreased from 1.1 (0.7-1.5) to 0.5 (0.2-0.7). Surgery decreased for extrahepatic cholangiocarcinoma (56 to 23%, p = .027), ampullary cancer (80 to 48%, p = .03) and overall bile tract cancer (61 to 32%, p < .0001) but use of chemotherapy increased (4 to 32%, p < .0001). Five-year relative survival rates for men were 15% and 24% for women. No significant improvement was found in survival.; Overall incidence of bile tract malignancies increased in males and GBC decreased in women. Long-term survival is poor and did not improve despite changes in treatment.
Description: To access publisher's full text version of this article click on the hyperlink at the bottom of the pageThu, 01 Dec 2016 00:00:00 GMThttp://hdl.handle.net/2336/6200902016-12-01T00:00:00ZLæknaskóli í 140 árhttp://hdl.handle.net/2336/620089
Title: Læknaskóli í 140 ár
Authors: Magnús Karl Magnússon
Description: Efst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinnFri, 02 Dec 2016 00:00:00 GMThttp://hdl.handle.net/2336/6200892016-12-02T00:00:00Z