I would think it would be a fairly clean acoustic-like tone with some mild reverb, probably with a low- mid-range tone setting on amp and/or guitar. I believe they played that with the hollow bodies, so you'll be looking for tone settings to replicate that kind of depth and resonance.

There were a lot of beautiful moments. The story tells you of a boy who became a star and later just a man who loved to play guitar, raised his children, and gardened. I was brought to tears when they told the story of Lennon's death. And again when we said goodbye to Harrison. They talk about how he backed "Life of Brian" and about so many things he did after the Beatles. His son spoke of how he constantly broke the rules and how George supported him. Here's a song that he did that spoke to how he couldn't be one of the masses. I always loved this tune...