Researchers at the MIRA research institute of the University of Twente and the Radboudumc have created a 'living membrane' combining kidney epithelial cells with a polymeric artificial membrane. This achievement is a first ...

You've never seen cilia like these before. Brandeis University researchers have developed a new model to study these tiny but vital cellular structures with more clarity and detail than ever before, providing a clearer picture ...

Chronic kidney disease in older cats is the focus of a fifth clinical trial under way at Colorado State University's James L. Voss Veterinary Teaching Hospital, where veterinarians are exploring novel stem-cell therapy that ...

(Phys.org) —Diseases affecting the kidneys represent a major and unsolved health issue worldwide. The kidneys rarely recover function once they are damaged by disease, highlighting the urgent need for better knowledge of ...

(Phys.org)—Detecting whether a patient will have acute kidney injury could become as simple as dipping a paper test strip printed with gold nanorods into a urine sample, a team of Washington University in St. Louis researchers ...

(PhysOrg.com) -- A team of researchers working in Hong Kong have discovered a new virus they are calling feline morbillivirus (FmoPV). It is apparently related to the virus that causes measles and mumps in humans and another ...

When evaluating early kidney injuries in people, doctors monitor blood level increases of creatinine, a waste product of muscle breakdown, to understand the severity of the injury. Creatinine is filtered by the kidneys, and ...

Reginald C. Farrow and Zafer Iqbal, research professors at NJIT, were awarded a patent today for an improved method of fabricating arrays of nanoscale electrical probes. Their discovery may lead to improved diagnostic tools ...

Renal function

Renal function, in nephrology, is an indication of the state of the kidney and its role in renal physiology. Glomerular filtration rate (GFR) describes the flow rate of filtered fluid through the kidney. Creatinine clearance rate (CCr) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR. Both GFR and CCr may be accurately calculated by comparative measurements of substances in the blood and urine, or estimated by formulas using just a blood test result (eGFR and eCCr).

The results of these tests are important in assessing the excretory function of the kidneys. For example, grading of chronic renal insufficiency and dosage of drugs that are primarily excreted via urine are based on GFR (or creatinine clearance).

It is commonly believed to be the amount of liquid filtered out of the blood that gets processed by the kidneys. Physiologically, these quantities (volumetric blood flow and mass removal) are only related loosely.