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Projects and Research lines

MicroRNA expression profiles in hepatocellular carcinoma, and efficacy of anti-MIR in experimental models

Mount Sinai School of Medicine – Office of Technology and Business Development

Our group has recently reported a molecular classification of HCC based on miRNA profiling (Toffanin S et al. Gastroenterology 2011). The study also identified a miRNA implicated in the progression of HCC. The project aims to explore the therapeutic possibilities of translation this miRNA into a novel antitumor agent in HCC.