Inflammatory and regenerative responses in salmonids following mechanical tissue dama

Publication year: 2010Source: Fish & Shellfish Immunology, Volume 29, Issue 3, September 2010, Pages 440-450</br>
H.C., Ingerslev , T., Lunder , M.E., Nielsen</br>
Locale responses in muscle tissue against either a sterile tissue damage or infection were compared in salmonid fish in order to examine the inflammatory responses and regeneration of tissue. From higher vertebrates both damage and infection are known to cause inflammation since DAMPs released from injured cells as well as PAMPs from the surface of pathogens are immunogenic. To examine this in salmonid fishes, Atlantic salmon (Salmo salar) were infected with Moritella viscosus, the causative agent of winter ulcer. Muscle tissue was sampled from infected fish at 4, 7 and 14 days post infection. Samples were obtained from site of...</br>