When comparing LastPass vs simplesafe, the Slant community recommends LastPass for most people. In the question“What is the best cross-platform password manager?”LastPass is ranked 4th while simplesafe is ranked 37th. The most important reason people chose LastPass is:

LastPass keeps an encrypted copy of all passwords locally as well as an encrypted copy on their servers. That way, passwords can be accessed locally while offline, or through their server while online from any machine.

Pros

Pro

Automatic cloud backup and cross-device sync

LastPass keeps an encrypted copy of all passwords locally as well as an encrypted copy on their servers. That way, passwords can be accessed locally while offline, or through their server while online from any machine.

Pro

Seamless autofill and password generator via plugins for all popular browsers

All common browsers, including Opera, have plugins that allow automatically filling in forms and generating passwords. All form fill information syncs across all platforms, devices and browsers. Password generator can be adjusted to use or exclude certain characters and patterns.

Pro

Yubikey Support

Pro

Can create one-time passwords for accessing the Vault

LastPass allows creating passwords for accessing the LastPass Vault that can only be used once. Great for accessing the Vault in public or untrusted places.

Pro

Password One-Click Change

LastPass is able to change your password automagically.

Pro

Allows downloading an encrypted database backup that can only be decrypted with LastPass Pocket

LastPass Pocket is a standalone personal database decrypter. It's a portable executable, meaning it does not need to be installed, that is used to decrypt a local encrypted copy of the password database.

Pro

Vetted by Steve Gibson

Steve Gibson is a well established security researcher best know for his work with Apple and Atari systems as well as founding Gibson Research Corporation. He was given access to LastPass' source code and confirmed that it's safe to trust its security.

Pro

Credit monitoring in US

LastPass can be set to notify if a user's credit report suddenly changes.

Pro

Offers multiple export options

LastPass can dump the whole database as a .csv file or an encrypted file that can then be decrypted using LastPass Pocket as well as separately export Wi-Fi passwords and autofill information. Additional export options are available on a per-browser basis.

Pro

Works even with browsers that don't support plugins

Via a clever use of bookmarklets, LastPass works on browsers that don't inherently support bookmarklets, like Opera or Safari on iOS.

Pro

One click copy to clipboard

All data fields can be one clicked to copy to clipboard.

Pro

Customizable

Completely customizable, users can set as many data fields or users as they like.

Cons

Con

Not free/libre

This application is proprietary, and thus cannot be modified, freely distributed, or trusted to be secure.

Con

Forced cloud backup

The is no way to opt-out of saving all of passwords on LastPass servers.

Con

When generating passwords, LastPass tends to put the wrong info in forms

For forms with both an email address and username, LastPass tends to mix up and overwrite information.

Con

Somewhat poor customer service

LastPass maintains a support forum which they mostly ignore, labeling it "mostly peer-to-peer support" leaving only their e-mail ticket system to turn to.

Con

History of bad support for the company behind LastPass

You never know how much you will pay for it because LogMeIn did the same with Hamachi product. Support will be bad.

Con

Forgets to ask "add new site?" on some websites

So you are forced to add a new site manually, which takes too long (relatively speaking).

Con

Mobile apps are not intuitive

Con

Doesn't always log out when idle

This issue is especially common with the mobile app.

Con

Backups are up to the user

There is no service with this application, it is up to the end user to backup all data.