The 1100 series includes updated rules deeming items that statutorily come under the definition of "tobacco product" to be subject to the Federal Food, Drug, and Cosmetic Act as amended by the Tobacco Control Act. The items affected include E-cigarettes, Hookah tobacco, and pipe tobacco.[5]

The 1200 series consists of rules primarily based in laws other than the Food, Drug, and Cosmetic Act:

1240 Rules promulgated under 361 of the Public Health Service Act on interstate control of communicable disease, such as: