Understanding the translational link between animals and humans; navigating the pitfalls of early drug discovery; and evaluating the potential of immunotherapies will be a major focus, as will hearing from a selection of biotech and pharma companies currently undertaking clinical research. This will include case studies from Pfizer, MedImmune, Merck, Visterra and ContraFect.

Event highlights will include a keynote presentation by Tim Opperman, Senior Research Scientist from Microbiotix.

The talk will discuss advances in the three-prong approach taken by Microbiotix to address the problem of MDR Gram-negative pathogens. It is claimed that all three discovery projects have demonstrated efficacy in murine models of infection.

Project 3 Novel Essential Target: The talk will explore how a series of novel oxadiazoles bind to a unique site on the ribosome, resulting in potent inhibition of the essential non-stop ribosome rescue pathway in Gram-positive and negative pathogens, including MDR Neisseria gonorrhoeae and Francisella tularensis. These compounds exhibited potent antibacterial activity and oral bioavailability.

A full speaker line-up and detailed agenda is available at www.superbugs-usa.com

Superbugs & Superdrug’s USA will take place on 13th and 14th November at the Renaissance Woodbridge Hotel in Iselin, New Jersey.

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