Bile acid sequestrants have been reported to impair the absorption of numerous nutrients, including
calcium
,
folate
,
iron
,
vitamin A
,
vitamin B
12
, and
vitamin E
.
1,2
It appears, however, that only folate supplementation may be needed by individuals on long-term therapy with bile acid sequestrants. Although the bile acid sequestrant used in the studies interfered with the absorption of the other nutrients, their levels remained in the normal range. Just to be safe, though, making sure to get enough vitamin E and vitamin A (in the form of beta-carotene) would make sense.

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