Abstract

Objective

Methods

Following institutional approval and written informed consent, both DBT and DSCV were obtained in women with a screening abnormality. The diagnostic accuracy of DBT and DSCV was evaluated by two radiologists of varying experience (Reader1 and Reader2).

Results

52 consecutive recalled women without calcification (mean age: 51 ± 12 years) underwent DSCV and DBT. Overall sensitivity was equal for both techniques (100% [95% CI, 91–100%] for DBT and 100% [95% CI, 91–100%] for DSCV). Overall specificity was higher for DBT (100% [95%CI, 91–100%]) than for DSCV (94% [95% CI, 91–100%]). Specificity for DSCV was higher for Reader1 (95% [95% CI, 91–100%]). Reader2 had lower values of specificity (92% [95% CI, 90–92%]). On DSCV, three and two false positives were recorded by Reader2 and Reader1, respectively. Overall, the area under the curve (AUC) was greater for DBT (AUC = 1) than for DSCV (AUC = 0.963). The mean difference between the two techniques was not significantly different (P = 0.43).

Conclusion

In this dataset, diagnostic accuracy of digital breast tomosynthesis is at least equal to that of digital spot compression.