USB and 9-in-1 card reader

Hi, I'm having an issue with my USB ports and 9in1 media card reader.....they don't seem to respond.....I don't know when they stop responding...probably a month or two ago.....but all I know they're not working.....evening the usb's in the back don't work....now the i have power in the usb ports but like i said.....they don't respond to computer.....any suggestions........thank you in advance.....