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Pfizer understands that your personal and health information is private. The information you provide will only be used by Pfizer and parties acting on its behalf to send you the materials you requested and other helpful information and updates on CELEBREX and/or arthritis, as well as related treatments, products, offers, and services.

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Scroll for Important Safety Information and Indications.

IMPORTANT SAFETY INFORMATION

All prescription NSAIDs, like CELEBREX, ibuprofen, naproxen, and meloxicam have the
same cardiovascular warning. They may all increase the chance of heart attack or
stroke that can lead to death. This chance increases if you have heart disease or
risk factors for it, such as high blood pressure or when NSAIDs are taken for long
periods.

CELEBREX should not be used right before or after certain heart surgeries.

Serious skin reactions, or stomach and intestine problems such as bleeding and ulcers,
can occur without warning and may cause death. Patients taking aspirin and the elderly
are at increased risk for stomach bleeding and ulcers.

Tell your doctor if you have:

A history of ulcers or bleeding in the stomach or intestines

High blood pressure or heart failure

Kidney or liver problems

CELEBREX should not be taken in late pregnancy.

Do not take CELEBREX if you have bleeding in the stomach or intestine, or you've
had an asthma attack, hives, or other allergic reactions to aspirin, any other NSAID
medicine or certain drugs called sulfonamides.

Life threatening allergic reactions can occur with CELEBREX. Get help right away
if you've had swelling of the face or throat or trouble breathing.

Prescription CELEBREX should be used exactly as prescribed at the lowest dose possible
and for the shortest time needed.

INDICATIONS

CELEBREX is indicated for the relief of the signs and symptoms of osteoarthritis,
rheumatoid arthritis, and ankylosing spondylitis, and for the management of acute
pain in adults.

Have a question? Call us at 1-888-678-2692.

Patients should always ask their doctors for medical advice about adverse events.

You may report an adverse event related to Pfizer products by calling1-800-438-1985 (U.S. only). If you prefer, you may contact the U.S. Food and Drug
Administration (FDA) directly. The FDA has established a reporting service known
as MedWatch where healthcare professionals and consumers can report serious problems
they suspect may be associated with the drugs and medical devices they prescribe,
dispense, or use. Visit www.fda.gov/medwatch
or call 1-800-FDA-1088. By clicking on this link, you will be leaving Celebrex.com.
This website is neither owned nor controlled by Pfizer. Pfizer is not responsible
for the content or services of this site.

The product information provided in this site is intended for residents of the United
States. The products discussed herein may have different product labeling in different
countries.

The health information contained herein is provided for educational purposes only
and is not intended to replace discussions with a healthcare provider. All decisions
regarding patient care must be made with a healthcare provider, considering the
unique characteristics of the patient.

You are encouraged to report negative side effects of prescription drugs to the
FDA. Visit
www.fda.gov/medwatch or call 1-800-FDA-1088. By clicking on this link, you
will be leaving celebrex.com. This website is neither owned nor controlled by Pfizer.
Pfizer is not responsible for the content or services of this site.

The product information provided in this site is intended for residents of the United
States. The products discussed herein may have different product labeling in different
countries.

The health information contained herein is provided for educational purposes only
and is not intended to replace discussions with a healthcare provider. All decisions
regarding patient care must be made with a healthcare provider, considering the
unique characteristics of the patient.

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Pfizer RxPathwaysTM can connect you with services to
help you pay for your Pfizer medicines.

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Scroll for Important Safety Information and Indications.

IMPORTANT SAFETY INFORMATION

All prescription NSAIDs, like CELEBREX, ibuprofen, naproxen, and meloxicam have the
same cardiovascular warning. They may all increase the chance of heart attack or
stroke that can lead to death. This chance increases if you have heart disease or
risk factors for it, such as high blood pressure or when NSAIDs are taken for long
periods.

CELEBREX should not be used right before or after certain heart surgeries.

Serious skin reactions, or stomach and intestine problems such as bleeding and ulcers,
can occur without warning and may cause death. Patients taking aspirin and the elderly
are at increased risk for stomach bleeding and ulcers.

Tell your doctor if you have:

A history of ulcers or bleeding in the stomach or intestines

High blood pressure or heart failure

Kidney or liver problems

CELEBREX should not be taken in late pregnancy.

Do not take CELEBREX if you have bleeding in the stomach or intestine, or you've
had an asthma attack, hives, or other allergic reactions to aspirin, any other NSAID
medicine or certain drugs called sulfonamides.

Life threatening allergic reactions can occur with CELEBREX. Get help right away
if you've had swelling of the face or throat or trouble breathing.

Prescription CELEBREX should be used exactly as prescribed at the lowest dose possible
and for the shortest time needed.

INDICATIONS

CELEBREX is indicated for the relief of the signs and symptoms of osteoarthritis,
rheumatoid arthritis, and ankylosing spondylitis, and for the management of acute
pain in adults.