i imagen not, the car in F2 worked out because the map wasn't used in the same way as the rest of the game play, and in an FPS style seting it may make it too easy to fight monsters and travel past high level places, borderlands was able to pull it off but it had a liner pergression so i doubt there will be any cars to drive, at lest not at this time in the fallout games, maybe in Fallout 4 or 5 but not with the current system