Fluprazine hydrochloride decreases play behavior but not social grooming in juvenile male rats

Abstract

Treatment with 8 mg/kg fluprazine hydrochloride strongly inhibited the play behavior of juvenile male rats but had no effect on social grooming. The results indicate that fluprazine affects play behavior as well as conspecific and predatory attack, male copulation, and maternal behavior. These drug actions may result from a rather generalized disruption in higher order stimulus processing or a drug-induced potentiation of fearfulness.