Unlike VisualWorks, you don't need to highlight that code - simply pull down the Smalltalk menu in the workspace and try "Insert" (which will print the results into the workspace) - you should end up with Excel opened up, with "Fred" in A1 and "Flintstone" in A2, and "Fred" in your workspace at the bottom - like this:

That's pretty much it - you can explore the available COM APIs and work from there - but this should get you started.