Lou Johnson (born September 22, 1934 in Lexington, Kentucky) is a former Major League Baseball left fielder in Major League Baseball. From 1960 through 1969, Johnson played for the Chicago Cubs (1960, 1968), Los Angeles Angels (1961), Milwaukee Braves (1962), Los Angeles Dodgers (1965-67), Cleveland Indians (1968) and California Angels (1969). He batted and threw right handed.

Johnson was signed by the New York Yankees as an amateur free agent in 1953. After kicking around in the minor leagues for a decade, Johnson finally made it into the major leagues for good in 1965 with the Los Angeles Dodgers, after a broken leg in early May sidelined regular left fielder Tommy Davis for the remainder of the season. In that season he scored the only run in Sandy Koufax's perfect game when he walked, went to second base on a sacrifice bunt, stole third and scored on a throwing error by Chicago Cubs catcher Chris Krug. In the 1965 World Series, Johnson hit two home runs, including the game winner in the clinching Game Seven.

In an eight-season career, Johnson posted a .258 average with 48 home runs and 232 RBI in 677 games.