Palookaville (also frequently appears as both Palooka-Ville and Palooka-ville) is a comic book written and drawn by cartoonist Gregory Gallant, better known as Seth, and published by Drawn & Quarterly. The first issue appeared in April 1991 and it has been irregularly published ever since. The comics are generally portrayals filled with lost, lonely characters searching for meaning, often reaching back into the past. They are known to be deeply affecting and almost indescribably weighty.

The first 19 issues were published in traditional comic book (pamphlet) format approximately annually (from 1991 to 2008), while the 20th issue (2010) was published in much-expanded book (hardcover) format, and is now planned to continue in this format annually or semiannually (21st issue scheduled for 2012), owing to changes in the American comic book market, specifically the decline in sales of single-issue comic books during the decade 2000–2010.[2][3]