If you've also been doing this a while you might think "hey, we tried this, but the libraries weren't good enough"

Okay -- so there are some people, I think they're mostly in Germany (but we won't hold that against them) and they are synthesizing something like every human peptide. If you haven't seen it, I recommend you check it out here.

NIST also hasn't been sitting around doing nothing all these years either. They've already made a huge libraries of increasing quality -- and they've already made spectral libraries of the first ProteomeTools release.