Shortly after Allen's selection training in The Pit for Task Force 141, Foley and his squad are deployed to rescue BCT-One, which is trapped in a militia-held town near Firebase Pheonix. He first leads his squad to defend the bridge layer from large volumes of RPG's fire from the OpFor across the river. After the bridge is laid, he leads his men into the city in Humvees, where they are ambushed by the militia. They put up a good fight, taking down many militiamen, although the Humvee is eventually destroyed. They are then forced to take cover in an enemy-occupied apartment, clearing their way through it. After they clear the building, they receive a distress call from Hunter Two-Three, and assist by clearing out a heavily defended school. They then fight their way from the school to the LZ, rendezvousing with General Shepherd's men.

en masse (of force) at their position. Under Foley's command, the Rangers successfully hold off the incoming Russians, including two BTR-80's and two Mi-28 gunships, until a friendly convoy arrives to evacuate them from the besieged area.

Foley and his squad are later deployed to Arcadia County to aid in the evacuation of civilians with the help of a Stryker ICV, callsign Honey Badger. The Rangers destroy AA batteries threatening the evacuation choppers, but are then ordered by General Shepherd to secure an unknown HVI. However, the Rangers are too late and find the HVI dead.

Hunter 2-1 is then deployed to Washington D.C., facilitating the evacuation of civilians and wounded personnel in the city. During the evacuation process, the Rangers assault the Department of Commerce, where an enemies crow's nest on the fifth floor is hammering the evacuation site. Foley and his team manage to take it and proceed to use the munitions left behind by the slaughtered Russians to take the fire off the evacuation site by killing foot-mobiles armed with Javelin's, and other weapons. They use the Javelin's to destroy Mi-28's, and other enemy vehicles. Soon after, they come under attack from enemy forces attempting to retake the crow's nest. After successfully holding them off, the Rangers proceed to the roof and link up with U.S. Navy SEALs and a UH-60 Blackhawk. Foley and his men board the Black Hawk and attack enemy forces at various monuments. Evacuation Order April is then enabled, prompting the Americans to "get the hell out of there." However, their helicopter is damaged by anti-aircraft fire, cutting off their means of escape. Foley, however, orders the pilot to attack the SAM-laden Department of Justice to take down as many SAMs as possible to clear the skies for other aerial vehicles. The effort is partially successful until the Black Hawk is shot down.

After the crash-landing of the Black Hawk, Foley, Dunn, Ramirez and other Rangers are surrounded by Russians, making a seemingly last stand. A soldier tosses a gun to Ramirez, and is sequentially shot and killed. An Mi-28 moves in position to fire on the Rangers when the nuke launched by Captain Price detonates in the sky, sending an EMP across the eastern United States and crippling the Russian forces, thus saving the Rangers' lives. With all electronic equipment down, Foley and his squad move through the quiet streets and run into Pvt. Vaughan, who is relaying orders from Colonel Marshall to assemble at the White House in order to retake it. Making their way to the White House via the President's bunker, Foley and his men emerge on the southern lawn of the White House, already under siege, and meet up with Marshall. Foley leads his squad in the re-taking of the building, fighting their way through the weakened enemy forces. Dunn discovers that the Air Force will carpet bomb the city as part of the "Hammerdown Protocol" unless the Rangers can retake it and signal they are still "combat effective". In a harrowing last-minute ditch effort, Ramirez and another Ranger make it to the top of the White House and pop their flares, aborting the bombing run seconds before the Air Force jets fly by. Foley and his men then regroup on the White House roof and look out at the burning ruins of Washington D.C., vowing revenge on the Russians.

According to the Hardened Edition handbook, the developers gave him his helmet of equipment to show his leadership position in the squad.

Foley is known to refer to Ramirez constantly throughout the campaign when giving commands, usually beginning with him shouting "Ramirez!" followed by an order. In total there are 56 different scripted lines for Foley and it has created an internet meme entitled "Ramirez, Do Everything!", in which Foley says Ramirez's name followed by something ludicrous, such as "Ramirez! Stop that AC-130 with this banana!" or "Ramirez! Here's a knife, now take out that Pave Low!"