Lortab is made up of Hydrocodone (related to codeine). It is in a class of
drugs called narcotic analgesics. Lortab is prescribed to relieve pain. It
may be taken with or without food. When taken with alcohol, it can intensify
drowsiness. It may interact with monoamine oxidase inhibitors, as well as other
drugs that cause drowsiness. It is in FDA pregnancy category C: its effect
on an unborn embryo or fetus is not clearly known and pregnant women should
consult their physicians before taking it.

How Lortab Works
Lortab acts by attaching to specific proteins called opioids
receptors, which are found in the brain, spinal cord, and gastrointestinal
tract. When these
compounds attach to certain opioids receptors in the brain and spinal cord,
they can effectively change the way a person experiences pain. In addition,
opioids medications can affect regions of the brain that mediate what we perceive
as pleasure, resulting in the initial euphoria that many opioids produce. They
can also produce drowsiness, cause constipation, and, depending upon the amount
taken, depress breathing. Taking a large single dose could cause severe respiratory
depression or death.

Lortab Addiction
Chronic use of Lortab can result in tolerance to the medication so that higher
doses must be taken to obtain the same effects. Long-term use also can lead
to physical dependence—the body adapts to the presence of the substance
and withdrawal symptoms occur if use is reduced abruptly. Individuals taking
prescribed Lortab should not only be given these medications under appropriate
medical supervision, but also should be medically supervised when stopping
use in order to reduce or avoid withdrawal symptoms. Symptoms of withdrawal
can include restlessness, muscle and bone pain, insomnia, diarrhea, vomiting,
cold flashes with goose bumps (“cold turkey”), and involuntary
leg movements.

Lortab abuse has been escalating over the last decade. There has been large
scale diversion of hydrocodone. For example, an estimated 7 million dosage
units were diverted in 1994 and over 11 million in 1997. In 1998 there were
over 56 million new prescriptions written for hydrocodone products and by 2000
there were over 89 million. From 1990 the average consumption nationwide has
increased by 300%. In the same period there has been a 500% increase in the
number of Emergency Department visits attributed to hydrocodone abuse with
19,221 visits estimated in 2000. In 1997, there were over 1.3 million hydrocodone
tablets seized and analyzed by the DEA laboratory system. A recent petition
submitted to the DEA has requested a review of the control status of all hydrocodone-containing
products.

Lortab Side Effects
Common side effects of Lortab include dizziness, lightheadedness, nausea,
drowsiness, euphoria, vomiting, and constipation. Some less common side effects
are allergic reaction, blood disorders, changes in mood, mental fogginess,
anxiety, lethargy, difficulty urinating, spasm of the ureter, irregular or
depressed respiration and rash.