personally, I doubt it'll be nukes as much as an economic deterioration beginning with the government and spreading outward through utilities and finally to food. As people grow hungrier, chaos and death will reign, at least in cities. Also, I don't find the music particularly mournful.

'Ol Glory is still flying, and thanks to the bomb shelter I dug last year, my stockpiles of Vienna Sausage and illicit weapons cache, I'll emerge as king of the waste land while the rest of you devolve into freakish neck-beard dork-mutants fighting over undigested morsels of potted meat left in my fecal pile. MUUUAAAhhhhhhhh!!!!!!