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Direct maternal lineages can be traced with a mitochondrial DNA (mtDNA) test. Children, both male and female, inherit their mtDNA from their mothers. MtDNA testing can be used as evidence in genealogy and for personal ethnic ancestry. It is commonly used in studies to show migrations of population groups across time and geography.

Using autosomal DNA allows genealogists to match cousins and close relatives from all of their family lines. Autosomal DNA also allows those interested in personal ethnic origins to discover connections to geographic based ethnic groups in recent and distant times.