No sector today is protected from having new and rising technologies turn them upside down. To better prepare, McKinsey came up with a list of technology trends that will continue to upset business as CEOs have known it, and that companies should be prepared to outsmart or overcome.

CEOs have been fixating on the importance of millennials as consumers and workers. But have they thought about the kind of leaders the members of Generation Y will become as they age and climb into important positions in their businesses? And more importantly, how the grooming and mentoring process might need to change to optimize their growth and their strengths?

The way women came to occupy the important role of the main “knowledge worker” at AskPower is an interesting case study in how even very traditional mid-market companies are becoming successful laboratories for cultural change that can elevate women in manufacturing settings and make companies better competitors.

The strong dollar has undercut export potential for just about every American company. But middle-market firms, in particular, seem to be weak in this area. A new report from American Express and Dun & Bradstreet found some strong but limited outposts for exporting. For example, just 10% of mid-market companies in Florida, the leading percentage, engaged in exports, followed by New Jersey, 8%; North Carolina, 7%; and Illinois, 6%. And these are the U.S.’ leaders.

Content marketing has become an integral part of most companies’ marketing strategies today. Yet while the initial surge was mainly by consumer-facing companies, B2B companies are picking up speed and finding success using content to draw clients in and build relationships.

Middle-market companies are feeling the talent squeeze more than larger companies, primarily because they are competing head on with their larger counterparts and can’t offer the benefits, marquee recognition of a Fortune 1000 or the innovative culture and growth and career fulfillment that small companies and startups do. But mid-market CEOs can compete effectively for the same talent.

Nearly half of American jobs could be automated in “a decade or two,” according to a recent argument by two researchers in The Economist. The jobs of everyone from telemarketers to title examiners to watch repairers to library technicians have become endangered by advances from the Internet of things, while many of those that have been deemed safe from such disruption are hands-on healthcare-related occupations: mental-health social workers, oral surgeons, prosthetists and recreational therapists. Yet, as this phenomenon unfolds, it underscores areas of opportunity, not only for individuals, but also for companies organized around their skills.

The new CEO of global food company, Danone, the French parent of Dannon USA, ground operations almost to a halt recently for a 90-minute all-company meeting that was attended in person or via video by an estimated 75,000 of the yogurt maker’s roughly 100,000 employees worldwide. Emmanuel Faber’s ambitious gambit to get their attention was a stunning move from which other chiefs could learn.

CEOs and business owners should beware: with a fresh round of VC funding, startups are popping up like weeds in a lawn. As a result, large and mid-market businesses are finding themselves being surprisingly disrupted. Our advice to all CEOs: be prepared to counter this trend.