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EAST LIVERPOOL, Ohio (AP) - Authorities say 100 people have been charged with hundreds of counts of drug trafficking, including allegations of flooding the state with doses of deadly synthetic opioids.

Investigators allege the drug trafficking ring has operated mainly between Cuyahoga (ky-uh-HOH’-guh) and Columbiana counties in eastern and northeastern Ohio since 2014.

A 756-count indictment against 100 individuals following a probe by the state Bureau of Criminal Investigation and the Columbiana County Drug Task Force in East Liverpool was announced Tuesday.

Defendants are charged with trafficking in cocaine, heroin and the synthetic opioids fentanyl and carfentanil.

Two suspects are charged with felony assault for allegedly exposing an East Liverpool police officer to fentanyl during a traffic stop earlier this year.