Ticlopidine is used to lessen the occurrence of cerebrovascular accidents( CVA). It is given to those with a history of stroke. Because ticlopidine can cause serious side effects, especially during the first 3 months of treatment, it is used mostly for people who cannot take aspirin to prevent strokes. Ticlopidine reduces the chances of thrombus formation, by preventing platelets from aggregating.

Precaution should be taken in Coagulation defects ( such as hemophilia and Von Willebrand's disease) and Hepatic disease. Gastric ulcers: the chances of serious bleeding may be increased. In Renal Impairment Ticlopidine is excreted from the body more slowly, which may increase the chance of adverse effects.