CAVER is a software tool for analysis and
visualization of tunnels and channels in protein structures. Tunnels
are void pathways leading from a cavity buried in a protein core to
the surrounding solvent. Unlike tunnels, channels lead through the protein
structure and their both endings are opened to the surrounding solvent.
Studying of these pathways is highly important for drug design
and molecular enzymology.

CAVER provides rapid, accurate and fully
automated calculation of tunnels and channels in static and dynamic structures.
The molecules amendable to analysis of CAVER
include proteins, nucleic acids, or inorganic materials.