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A free radical is an atomic structure with an unpaired electron in its outermost shell. These unpaired electrons tend to be highly reactive, resulting in chemical reactions such as oxidation. Because they have one or more unpaired electrons, free radicals are highly unstable. They scavenge the body to grab or donate electrons, causing damage to cells, proteins and DNA. Free radicals are naturally occurring; however, air pollution, stress, smoking, heavy exercising and aging all contribute to the creation of harmful free radicals. Free radicals can cause oxidative damage to the body, potentially leading to serious health problems. Normally the body is able to protect itself from the damaging effects of free radicals, but if antioxidants are unavailable, or if free-radical production becomes excessive, damage can occur.

Antioxidants are natural cell protectors, neutralizing free radicals by pairing an electron to the outermost shell of radical oxygen molecules, rendering them harmless. Antioxidants are nutrients such as vitamins and minerals, and enzymes that are capable of counteracting the damaging, but normal, effects of the physiological process of oxidation in bodily tissues. Antioxidants work in two ways: chain breaking and prevention. A chain-breaking antioxidant, such as vitamins A, C and E, stabilizes free radicals or causes them to decay into harmless atomic structures. A preventative antioxidant prevents the oxidation process by scavenging free radicals.

Isotonix Açai is an isotonic-capable dietary supplement, made from a combination of açai berries, guarana, yerba maté, mangosteen, pomegranate, green tea and essential and non-essential amino acids. The proprietary blend of Isotonix Açai works to increase energy, support immune functions, promote cognitive health and support weight control. The antioxidant properties set Isotonix Açai apart from most energy drinks on the market. Isotonix Açai will help the body stay energized and active while providing a sound antioxidant formula. Containing other antioxidant-laden ingredients like mangosteen and pomegranate, which have high ORAC values, Isotonix Açai is an asset to daily dietary supplementation.*

Ingredients

Açai Fruit Pulp: 200 mg/Açai Extract (100 mg)The açai berry has been harvested from the depths of the rainforests of Brazil by the people who have been using it for thousands of years. Açai berries contain thiamin (B1), riboflavin (B2), niacin (B3), vitamin E, vitamin C, phosphorus, calcium, potassium, fiber, proteins and fatty acids, such as Omega 6 and Omega 9. Açai berries contain some of the highest levels of antioxidants on the market with studies showing up to 33 times the antioxidant properties as red wine grapes. The dense pigmentation of açaí has led to several experimental studies of its anthocyanins, a group of polyphenols that give the deep color to fruits and vegetables and are high in antioxidant value.* Açai berries have two essential fatty acids known as omega 6 (linoleic acid) and omega 9 (oleic acid). Research shows that both omega 6 and omega 9 fatty acids help maintain HDL cholesterol levels.*

L-Phenylalanine (200 mg) L-Phenylalanine is an essential amino acid. Amino acids are the building blocks of protein. The body cannot produce L-phenylalanine so it must obtain it from diet or supplements. The main dietary sources of L-phenylalanine are high protein foods such as meat, fish, eggs and dairy products. Amino acids come in two forms, designated as L- and D- forms. The L- form is the naturally occurring form in foods, whereas the D- form is the synthetic variety. L-phenylalanine acts as an amino acid precursor boosting noradrenalin production, which in turn increases mental alertness. It suppresses appetite by fighting the sugar crash that commonly follows a binge on sugar or coffee, which isn’t at all uncommon. L-phenylalanine helps to provide steady energy throughout the day.* L -phenylalanine is an electrically-neutral amino acid, one of the 20 common amino acids used to biochemically form proteins and enzymes, coded by our DNA. L-phenylalanine is necessary for living organisms, including the human body. L-phenylalanine can be converted into L-tyrosine, another of the 20 protein-forming amino acids. L-tyrosine is converted into L-DOPA, which is further converted into dopamine, norepinephrine and epinephrine (latter three are known as the catecholamines). Vitamin B6, folic acid and vitamin C are needed in order to convert phenylalanine into noradrenaline. Noradrenalin is the brain’s natural energy source, promoting alertness, mental energy and focus.*

Pomegranate Extract (40% Ellagiac Acid) (50 mg) The pomegranate is native to the regions from Iran to the Himalayas in northern India. It was cultivated and naturalized over the Mediterranean region since ancient times. It is widely cultivated throughout India and the drier parts of Southeast Asia, Malaya, the East Indies and tropical Africa. The tree was introduced into California by Spanish settlers in 1769. In United States, it is grown mainly in the drier parts of California and Arizona for its fruits. The pomegranate is a rounded shrub or small tree that can grow to 20 or 30 feet, but more typically to 12 to 16 feet in height. Dwarf varieties are also known. It is usually deciduous, but in certain areas the leaves will persist on the tree. The trunk is covered by a red-brown bark which later becomes gray. The branches are stiff, angular and often spiny. There is a strong tendency to sucker from the base. Pomegranates are also long-lived. There are specimens in Europe that are known to be over 200 years of age. The vigor of a pomegranate declines after about 15 years, however. The nearly round, 2-1/2 to 5 in. wide fruit is crowned at the base by the prominent calyx. The tough, leathery skin or rind is typically yellow overlaid with light or deep pink or rich red. The interior is separated by membranous walls and white, spongy, bitter tissue into compartments packed with sacs filled with sweetly acid, juicy, red, pink or whitish pulp, or aril. In each sac there is one angular, soft or hard seed. High temperatures are essential during the fruiting period to get the best flavor. The pomegranate may begin to bear in one year after planting out, but two years is more common. Under suitable conditions the fruit should mature some five to seven months after bloom. The fruit can be eaten out of hand by deeply scoring several times vertically and then breaking it apart. The clusters of juice sacs are then lifted out and eaten. The sacs also make an attractive garnish when sprinkled on various dishes. Pomegranate fruits are most often consumed as juice. The sacs can be removed and put through a basket press or the juice can be extracted by reaming the halved fruits on an ordinary orange juice squeezer. Another approach starts with warming the fruit slightly and rolling it between the hands to soften the interior. A hole is then cut in the stem end which is placed on a glass to let the juice run out, squeezing the fruit from time to time to get all the juice. The juice can be used in a variety of ways: as a fresh juice, to make jellies, sorbets, cold or hot sauces, or as a flavoring to cakes, baked apples, etc. The juice can also be made into a wine. One pomegranate delivers 40 percent of an adult's daily vitamin C requirement, and is a rich source of folic acid and antioxidants. Pomegranates are high in polyphenols. The most abundant polyphenols in pomegranate are hydrolysable tannins, particularly punicalagins, which research has shown to be the antioxidant responsible for the free-radical scavenging ability of pomegranate juice.* Many food and dietary supplement makers have found the advantages of using pomegranate extracts (which have no sugar, calories or additives), instead of the juice, as healthy ingredients in their products. Many pomegranate extracts are essentially ellagic acid, which is largely a by-product of the juice extraction process. Ellagic acid has been shown in published studies to absorb into the body when consumed as ellagitannins such as punicalagins.*

Guarana Extract Ø (160 mg) Guarana extract is derived from the seeds of the South American guarana shrub ( Paullinia cupana) , most of which originates in Brazil. Traditional uses of guarana by natives of the Amazon Rainforest include mixing crushed seeds in foods and beverages to promote alertness, mental energy and focus. As a dietary supplement, guarana is an effective energy booster, as it contains about twice the caffeine found in coffee beans (about three to four percent caffeine in guarana seeds compared to one to two percent for coffee beans). Guarana may enhance mental performance. The seeds of guarana are known to be rich in xanthines (caffeine) and have been widely used as a tonic in many South American countries, particularly Brazil. In studies, which have determined the total xanthine content of guarana powder, caffeine content typically averages 30 to 50 percent (depending on the extract). Related compounds such as theobromine and theophylline are found at levels of (one to three percent) and, like caffeine, can be detected in the urine for up to nine days following guarana intake. Most of the scientific evidence on caffeine as a general stimulant and an aid to exercise performance shows convincingly that caffeine is effective.*

L-Taurine (125 mg) L-Taurine is a building block for all the other amino acids. It aids in the transport of potassium, sodium, calcium and magnesium in and out of cells, thus helping to generate nerve impulses. It is a non-protein amino acid and is found in high amounts in the brain, retina, myocardium, skeletal and smooth muscle, platelets and neutrophils. It is plentiful in the fluids of muscle, lungs and nerve tissue. Dietary taurine mainly comes from animal food sources. Taurine is also present, in lower levels, in plant food sources like seaweed. It is classified as an important amino acid and aids micelle formation and fat absorption. Further, it promotes alertness, mental energy and focus. Taurine also has antioxidant and membrane-stabilizing activities. It may also help maintain a healthy cardiovascular system while also delivering detoxifying activities.*

Mangosteen Powder (100 mg) The mangosteen is an evergreen tree about 10 to 25 meters tall, grown in tropical climates such as Asia, South America and Polynesia. Mangosteen fruit is often called the “Queen of Fruits” due to its pleasant flavor. The mangosteen fruit is round with slightly flattened ends and is about six to seven centimeters in diameter. It has a smooth, thick, firm rind that is pale green when immature and dark purple or red-purple when ripe. Enclosed by the rind is the edible pulp in four to eight white segments. Each fruit has one to two seeds. The mangosteen fruit contains a compound called xanthones, which is thought to have antioxidant properties. The plant is also a rich source of other bioactive molecules including flavonoids, benzophenones, lactones and phenolic acids. A variety of xanthones can be isolated from the hull, rind, heartwood and flesh of mangosteen plants and fruit. Some studies have demonstrated that the xanthones found in mangosteen have antioxidant properties; six xanthones found in the mangosteen fruit were isolated from the fruit peel.*

L-Tyrosine (100 mg) L-Tyrosine is an amino acid found naturally in our bodies. Tyrosine is metabolized into neurotransmitters such as dopamine, norepinephrine and epinephrine. Neurotransmitters are important because they carry messages from one nerve cell to another, thereby playing a vital role in our muscular and cognitive function. Scientists believe that the main cause of mental fatigue is directly related to decreased levels of dopamine, norepinephrine and other neurotransmitters in the brain. Many scientists believe that tyrosine can naturally relieve occasional symptoms of mental and physical fatigue.*

L-Glycine (100 mg) Glycine is an important amino acid that supports the body’s synthesis of non-essential amino acids. Glycine is one of the few amino acids that can spare glucose for energy by improving glycogen storage. Glycine is useful in the synthesis of DNA and is readily converted into creatine. The body requires glycine for the maintenance of the central nervous system. In men, glycine plays an essential role in maintaining healthy prostate functions.*

Yerba Maté Extract Ø (45 mg) Yerba maté is an evergreen with white flowers and red fruit, found naturally only in South America. Its medicinal parts are the dried or roasted leaves, which have proven to be a rich source of caffeine. Yerba maté contains xanthines, which are alkaloids in the same family as caffeine, theophylline and theobromine, well-known stimulants also found in coffee and chocolate. Yerba maté also contains potassium, magnesium and manganese . Like coffee, Yerba maté stimulates the central nervous system. It may promote strong heart contractions, heart rhythm, and may support the break down sugars in the body. It is largely used to fight occasional fatigue. Yerba maté has been shown to promote alertness, mental energy and focus, without the negative effects typically created by similar compounds. Yerba maté creates a powerful answer to occasional mental and physical fatigue. Yerba maté is used worldwide as a rejuvenator, body energizer and a mental alertness stimulator.*

Green Tea ‡ (25mg) Green tea extract has been used medicinally for centuries in India and China. A number of beneficial health effects are related to regular consumption of green tea and dried/powdered extracts of green tea that are available in some dietary supplements. Green tea is prepared by picking, lightly steaming and allowing the leaves to dry. The active components in green tea are a family of polyphenols (catechins) and flavonols, which possess potent antioxidant activity. Several catechins are present in major quantities; epicatechin (EC), epigallocatechin (EGC), epicatechin gallate (ECG) and epigallocatechin gallate (EGCG). EGCG makes up around 10 to 50 percent of the total catechin content and appears to be the most powerful of all the catechins, with antioxidant activity about 25 to 100 times more powerful than vitamins C and E. Green tea extract is reported to have positive effects, including cardiovascular system support.* Green tea contains a substantial amount of antioxidants, including epigallocatechin gallate (EGCG), which help to provide significant immunoprotective qualities. Green tea’s polyphenolic antioxidants support cardiovascular health, reduce free radical damage to cells, and supports the normal oxidation of LDL cholesterol. Aside from the clear benefits of green tea as an antioxidant, recent studies have suggested green tea may aid in promoting weight control.* ‡This extract is decaffeinated.

Vitamin C (100 mg) Vitamin C, a water-soluble vitamin that acts as an antioxidant, has been proven to be important for the growth of body tissues, support of cardiovascular health, reduced oxidative stress, and good cognitive health and performance.

Vitamin B6 (2.1 mg), B5 (4 mg), B12 (3.6 mcg), Folic Acid (50 mcg), and Niacinamide (15 mg) A vitamin B-complex of water soluble vitamins play an important role in cell metabolism, promoting a healthy immune system, supporting the functions of the nervous system, aiding in carbohydrate metabolism for energy, and promoting cognitive health and function.

Zinc (Gluconate) (1.25 mg) Zinc is largely found in fortified cereals, red meats, eggs, poultry and certain seafood, including oysters. Zinc is a component of multiple enzymes and proteins. It is also involved in the regulation of gene expression. Zinc is an essential trace mineral that has functions in 300 different enzymatic reactions. Thus, zinc plays a part in almost all biochemical pathways and physiological processes. More than 90 percent of the body’s zinc is stored in the bones (30 percent) and muscles (60 percent), but zinc is also found in virtually all body tissues. Zinc is involved in such a great number of enzymatic processes it has been found to positively affect a large range of physiological functions such as energy production, cognitive function and carbohydrate metabolism. Zinc is an essential amino acid that is involved in many enzymatic reactions in the body, ranging from the synthesis of proteins and collagen, to the production of cellular energy.* Ø Herbal source of caffeine (24 mg/serving)

Ingredients Label (click image to expland)

FAQs

How does Isotonix Açai compare with other energy drinks? Açai, unlike other energy drinks, provides strong antioxidant protection from various fruits powders and extracts, while also supplying energy promoting vitamins and amino acids.*

Since Açai is isotonic, why does it need caffeine? Would it not be more potent if it were more slowly absorbed? Caffeine is present as a natural component of the ingredients contained in Isotonix Açai. Whether isotonic or not, caffeine provides an extra ‘energy push’ for those who want it. No, this product would not be more potent if it were absorbed more slowly.*

Will there ever be a version of Isotonix Açai that is caffeine free? No. It would not be as effective.*

Are there any contraindications for Isotonix Açai? Yes. If you are currently taking monamine oxidase inhibitors (MAOI) or angiotensis converting enzyme (ACE) inhibitors, you should not take this product. If you have phenylketonuria (PKU), high blood pressure, thyroid disease/Graves's disease, schizophrenia or bipolar disorder, you should not take this product. Take this supplement separately from prescription medications. If you are taking any other prescription drugs or have an ongoing medical condition, you should consult your physician before using this product. Women who are pregnant or nursing should not use this product. Keep out of reach of children.

Can diabetics take Isotonix Açai? Diabetics should consult their physicians before taking any dietary supplement. Isotonix Açai contains two grams of sugar per serving. Fructose, the prominent sugar in Açai, scores a 19 on a 100-point scale for Glycemic Index.*

Can Isotonix Açai be taken with Isotonix OPC-3® ? Yes, Isotonix Açai and Isotonix OPC-3 would compliment each other when taken together. Can I take Isotonix Açai if I have high blood pressure? This would depend on which medication a person has been prescribed. For example, angiotensin converting-enzyme (ACE) inhibiting drugs may interact adversely with certain ingredients in Açai. Please see warning section on the label. If you are taking any medication, please check with your physician before starting any herbal nutritional product.*

Can Isotonix Açai be taken with other Isotonix products? If so, which ones? Yes. Isotonix Açai can safely be taken with other Isotonix products, provided one follows the recommended serving size for each product. Isotonix OPC-3®, Isotonix Maximum ORAC, Isotonix Calcium Plus, Isotonix Multivitamin, Isotonix Multimineral, etc., can all be taken with Isotonix Açai.*

How should I take Isotonix Açai? Pour two level capfuls (white screw cap) of the powder into a cup. Add 4 fl. oz. (line on the colored overcap indicates 2 fl. oz.) of water and stir. Are there any allergens in Isotonix Açai? Isotonix Açai is a vegetarian product and contains no wheat, soy, yeast, gluten, artificial flavor, starch, salt, preservatives or milk.

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Isotonix Vs. Standard Tablets, Capsules, or Soft Gels:

Isotonic, which means "same pressure," bears the same chemical resemblance of the body's blood, plasma and tears. All fluids in the body have a certain concentration, referred to as osmotic pressure. The body's common osmotic pressure, which is isotonic, allows a consistent maintenance of body tissues. In order for a substance to be absorbed and used in the body's metabolism, it must be in an isotonic state.

Isotonix dietary supplements are delivered in an isotonic solution. This means that the body has less work to do to obtain maximum absorption of the nutrients. The isotonic state of the suspension allows nutrients to pass directly into the small intestine and rapidly absorb into the bloodstream. With Isotonix products, little nutritive value is lost, making the absorption of nutrients highly efficient while delivering maximum results.

* These statements have not been evaluated by the Food and Drug Administration.
* This product is not intended to diagnose, treat, cure or prevent any disease.