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Researchers at OHSU’s Vaccine and Gene Therapy Institute believe they have discovered a promising delivery method to help make an HIV vaccine effective prior to, and perhaps after, infection

A new discovery at Oregon Health & Science University highlights an ingenious method to ensure the body effectively reacts when infected with the highly evasive HIV virus that causes AIDS. The same team of researchers has been utilizing this unique approach to develop its own HIV vaccine candidate, which has so far shown promising results in animal studies. This latest research finding will be published in the May 24, 2013, edition of the journal Science. Read more

OHSU research helps explain why an AIDS vaccine has been so difficult to develop

Research highlights why new methods developed at OHSU may be the most promising avenues for fighting the disease. For decades, a successful HIV vaccine has been the Holy Grail for researchers around the globe. Yet despite years of research and millions of dollars of investment, that goal has still yet to be achieved. Recent research by Oregon Health & Science University scientists explains a decades-old mystery as to why slightly weakened versions of the monkey AIDS virus were able to prevent subsequent infection with the fully virulent strain, but were too risky for human use, and why severely compromised or completely inactivated versions of the virus were not effective at all. Read more

Oregon Health & Science University researchers have received additional funding through Grand Challenges Explorations, an initiative created by the Bill & Melinda Gates Foundation, to conduct AIDS vaccine research. The funding enables individuals worldwide to test unorthodox ideas that address persistent health and development challenges. OHSU’s research funded through a $999,998 grant will take place at the Vaccine and Gene Therapy Institute on OHSU’s West Campus in Beaverton, Ore., and will be led by assistant scientist Jonah Sacha, Ph.D. Read more

Non-Human Primate Studies Reveal Promising Vaccine Approach for HIV

Research conducted at Oregon Health & Science University's Vaccine and Gene Therapy Institute (VGTI) has developed a vaccine candidate in non-human primates that may eventually lead to a vaccine against Human Immunodeficiency Virus (HIV). Details of this advance are published in the advance online edition of the journal Nature. The paper will also be published in an upcoming print addition of the journal. Read more