Police have issued a warrant for the arrest of a man over an alleged fatal stabbing outside a methadone clinic south of Sydney today.

NSW Police confirmed in a statement that 52-year-old Michael Graham Gale is wanted by authorities over his involvement in a fight on Denison Street in Wollongong around 6am, where 39-year-old Bulli man Steve Anthony Edwards was allegedly stabbed.

It is believed an altercation broke out on the footpath of the street as Edwards was on his way to the clinic before police found him with an apparent stab wound to his chest.

A police warrant has been issued for 52-year-old Michael Graham Gale over an alleged stabbing in Wollongong today. Picture: Supplied. (Supplied)

CPR was administered at the scene before he was transported to Wollongong Hospital, where he died a short time later.

Acting Superintendent Chad Gillies said earlier that the death is being treated as suspicious and that the two men were known to each other.

“My understanding at the moment is the altercation involved two people, which included the deceased and that male,” he said.

Steve Anthony Edwards, 39, from Bulli died today after allegedly being stabbed in an altercation outside a methadone clinic in Wollongong. (Supplied) (Supplied)

“Our goal at the moment is to speak with that individual to ascertain the circumstances of what occurred.”