[artist id="1340778"]Game[/artist] and [artist id="1230523"]Kanye West[/artist] have had quite the chemistry in the studio. But after producing a song on each of Game's first three albums, the Louis Vuitton Don will not be supplying any music for the West Coast rapper's upcoming The R.E.D. Album and that may be Game's fault.

"I dunno, I think I dissed Amber Rose while she was with [Kanye] and I think that kinda tainted our relationship a little bit," Game told Sway on Wednesday's "RapFix Live" after he was asked when he'd be working with Yeezy again.

"I reached out to Kanye at the beginning of the album and I seen him in L.A. He said he was gonna give me some beats, but he never did," the Compton MC said. "I didn't take it personal, I got nothing but love for 'Ye and the things that we did in the past."

The pair first collaborated when West hooked up the beat for "Dreams," a single off of Game's 2005 debut, The Documentary. The two then got together again on "Wouldn't Get Far," the model-dissing track off Game's second album, The Doctor's Advocate, and completed the hat trick in 2008 with "Angel" on the former G-Unit member's L.A.X. LP. But when the rapper drops The R.E.D. Album on August 23, the streak will end.

While Game admitted to some wrongdoing — throwing shots at Yeezy's former squeeze while the two were together — he insisted that he never directly disrespected Kanye. "I never shoot shots at Kanye, and if I do, it's always competitive and I'll clean it up on the next bar because I got a lot of love and a lot of respect for him."

Game also says he isn't hard-pressed for a Kanye track or feature. "What I'm saying is, I'm not waking up begging to work with Kanye, number one, but if it happens it happens; if it don't, it don't."

Sway then asked whether Game's persistent barbs at Jay-Z had anything to do with the distance between him and Kanye, considering the two are dropping their collaborative Watch the Throne album. Game didn't think that was a factor, noting that Kanye and Jay have always had a close relationship, and Game has been baiting Hov for years.

"I've been shooting shots at Jay from the beginning, but worked with 'Ye throughout," the Dr. Dre protégé said before putting the proverbial shoe on the other foot. "But I understand, because if you shoot a shot at Dre, then it's a possibility I might not work with you or I might not be as open to working with you. I understand it."

Would you like to see Game and Kanye get back in the studio together? Tell us in the comments!