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The main objective of the Cancer Incidence in Five Continents (CI5) series, published by the International Agency for Research on Cancer (IARC) and the International Association of Cancer Registries (IACR), is to present comparable data on cancer incidence for all countries around the world for which high-quality data have been made available by population-based cancer registries. CI5 is an invaluable source of information about the global burden and distribution of cancer, and Volume X has a wider coverage than ever, presenting high-quality standardized data for cancers diagnosed during the period 2003–2007 from 290 cancer registries in 68 countries.