The common understanding of morphogenesis implies a three-dimensional evolutionary change in form witnessed in the developmental process of an organism. This evolutionary process emerges from cell growth, cellular differentiation and environmental changes that generate specific conditions between genotype and phenotype. The complex nature of these aspects is intrinsic to evolutionary biology, and its accurate implementation in bio-generated architectures potentiates a twofold understanding of different morphogenetic strategies and its spatial consequences. Within this premise the morphogenetic factors of cell-differentiation and cell-signaling become a crucial aspect in a real-time communication system between an archetype and space, thus performing within particular modes in which design correlates to space. The paper hypothesizes and tests the use of Cell-Signaling as system of communication that governs fundamental cellular activities within the process of Gastrulation. This process occurs in early cell-embryo development and where communication between cells is favorably active and cellular the structure is established. The Emosphera project is a technical re-contextualization of this specific morphogenetic process. The principles denote a genetic code of the object can be scripted in a CAD environment and reproduced real-time by means of communication through a multimedia platform, which render form as a consequential aspect.