Valium News

VALIUM SUMMARY

Valium (diazepam) is a benzodiazepine derivative.

Valium is indicated for the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic.In acute alcohol withdrawal, Valium may be useful in the symptomatic relief of acute agitation, tremor, impending or acute delirium tremens and hallucinosis.Valium is a useful adjunct for the relief of skeletal muscle spasm due to reflex spasm to local pathology (such as inflammation of the muscles or joints, or secondary to trauma), spasticity caused by upper motor neuron disorders (such as cerebral palsy and paraplegia), athetosis, and stiff-man syndrome.Oral Valium may be used adjunctively in convulsive disorders, although it has not proved useful as the sole therapy.The effectiveness of Valium in long-term use, that is, more than 4 months, has not been assessed by systematic clinical studies. The physician should periodically reassess the usefulness of the drug for the individual patient.

Valproate versus diazepam for generalized convulsive status epilepticus: a pilot study. [2011.12]Background and purpose: Evidence-based data to guide the management of status epilepticus (SE) after failure of primary treatment are still scarce and the alternate needs to be found when phenytoin (PHT) is not available or contraindicated. Comparison of intravenous (IV) valproate (VPA) and diazepam (DZP) infusion has not been conducted in adults with SE...

Clinical Trials Related to Valium (Diazepam)

Comparison of Absorption of Vaginal Diazepam Using Different Delivery Systems [Terminated]
The purpose of this study is to determine which of three delivery systems of vaginal
diazepam have the best systemic absorption, measured by serum diazepam levels. The three
delivery systems are: moistened tablet, suppository or cream. Additionally the study will
compare the side effects and absorption of vaginal diazepam with oral diazepam. Vaginal
diazepam is used off-label vaginally to relax pelvic floor muscles and reduce pelvic pain
caused from pelvic floor dysfunction.

Benzodiazepines are often used to reduce anxiety and agitation during stressful situations -

including traumatic event.
These compounds may increase the likelihood of developing PTSD when administered few days

after the traumatic event - but their effect as an immediate intervention has not been

studied - despite their frequent and uninformed use at this stage.

This work will evaluate the effect of diazepam - a BZ compound - on PTSD symptom trajectory

following traumatic event in a randomized controlled design.
Following the studies of opiates it is hoped that diazepam, administered within hours of the
traumatic event, and before the first night sleep (a memory consolidating condition) will
reduce the likelihood of developing PTSD. However, an adverse effect cannot be excluded, and
thus the investigators posit a bidirectional hypothesis.
The importance of this work is that it will provide the necessary evidence to sanction a
frequently practiced use of benzodiazepines.

Reports of Suspected Valium (Diazepam) Side Effects

PATIENT REVIEWS / RATINGS / COMMENTS

Based on a total of 12 ratings/reviews, Valium has an overall score of 9. The effectiveness score is 9 and the side effect score is 9.33. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.

Valium review by 53 year old male patient

Rating

Overall rating:

Effectiveness:

Highly Effective

Side effects:

No Side Effects

Treatment Info

Condition / reason:

anxiety/depression

Dosage & duration:

5mg taken 3 times daily for the period of still taking

Other conditions:

depression

Other drugs taken:

paxil

Reported Results

Benefits:

The paxil ,valium combination releived my symtoms.

Side effects:

No side effects from valium,side effects from paxil were ,feeling off balance,sharp pains in the eyes,sexual disfunction. Finally went off paxil.

Comments:

I was prescribed paxil for depression, it worked but the side effects became to much after about 2 yrs, but for those 2 yrs . my depression and axiety were under control. The valium does releive my anxiety symtoms .
I was taking 20 mg paxil one time a day at waking and 5 mg valium 3 times a day if i was feeling nervous. Have since started taking a vitamin called GH3 and a liquid multi vitamin with cannibis at bed time, have been depression and anxiety free for one year.

Valium review by 35 year old female patient

Rating

Overall rating:

Effectiveness:

Highly Effective

Side effects:

Mild Side Effects

Treatment Info

Condition / reason:

sciatica and low back pain

Dosage & duration:

5 mg taken 1x a day for the period of 6 months

Other conditions:

none

Other drugs taken:

none

Reported Results

Benefits:

i had a severe fall and tore the psoas muscle and damaged the SI joint. Before i was in great physical shape. After I could barely walk a block. After PT which only mildly helped I asked for various meds. Vicodin helped some but left me hung over. Valium released the muscle seizures and allowed me slowly to return to exercise. It's not used much now that there's Flexeril, but F. can lead to depression and doesn't as effectively release muscle tension (in my case).

Side effects:

some sluggishness in the early morning, and sometimes an overall sense of dehydration, but that can be countered with drinking lots of fluids.

Comments:

I determined that the best solution was to take it before bed--i could sleep through the night with it, whereas without I often woke up and had to take more ibuprofen and still slept poorly.

Valium review by care giver of 29 year old male patient

Rating

Overall rating:

Effectiveness:

Marginally Effective

Side effects:

Mild Side Effects

Treatment Info

Condition / reason:

anxiety

Dosage & duration:

10mg taken one pill for the period of one instance

Other conditions:

none

Other drugs taken:

none

Reported Results

Benefits:

The valium was prescribed for the patient in an attempt to relieve anxiety prior to a minor surgery being performed.

Side effects:

The patient was still experiencing anxiety during the minor surgery. After the procedure was over, the patient experienced wobbly legs and had difficulty paying attention.

Comments:

Valium was prescribed for the patient to use prior to having minor surgery to relieve his anxiety.