"We're definitely going to have some changes on our roster," Phillies manager Charlie Manuel said. "How many or what, I don't really know."

Philadelphia first baseman Darin Ruf, who broke the Reading Phillies' single-season home run record with 38 this year, delivered a sacrifice fly in the fourth Wednesday. He drove in all eight Phillies runs in their last four games against Washington.

Another former Reading Phillie, right-hander Tyson Brummett, who spent parts of the last five seasons in Reading, made his major league debut in the eighth, allowing two singles and striking out two.

He was the fifth player who played for the R-Phils this season to make his major league debut, joining pitchers B.J. Rosenberg and Tyler Cloyd, catcher Steven Lerud and Ruf.

Perlozzo, former manager of the Baltimore Orioles, joined the Phillies as their third base coach for the 2009 season. He moved to first base in 2011.

Gross was Philadelphia's bench coach in 2001, then hitting coach from 2002-04 and from July 2010 until Wednesday.

Mackanin arrived in Philadelphia in 2009.

"We dug ourself in a pretty big hole pretty early, and ... it was almost too much to overcome," said left-hander Cliff Lee (6-9), who allowed three runs and eight hits in six innings Wednesday and finished with a losing record for the first time since 2007. "Next year, we've got to come in and start off better.

"Injuries hurt us pretty bad this year, but the other teams in this division have gotten better. So nothing is going to come easy.

"But if we're healthy and guys are out there playing the way we can, then we can beat anyone."

"We've run a lot of players through here," Manuel said. "We tried a lot of things."

Manuel's most common lineup (used four times) included Mike Fontenot, who played all of 47 games and was released in August.

The team was hamstrung by injuries and lack of suitable depth.

A decent second half (44-31) buoyed hope only for reality to ultimately strike.

The team's ratings on local TV dropped 39 percent, according to Sports Business Journal's annual survey, marking the largest decline in baseball.

The Phillies went from the best local ratings in 2011 to seventh in 2012.

"It's something you don't accept as a professional baseball player," closer Jonathan Papelbon said. "As a team unit you don't accept this and you have to find a way to come back next year and figure it out where we went wrong."