Known as San Simeon Grande, it was probably built in the 10th century. It underwent notable restorations, especially that in the 18th century by order of the health authority, who rebuilt the floor because of the burial of a plague victim in 1630. Inside there are some interesting works by Palma the Younger and a Last Supper by Tintoretto. Especially noteworthy is the monument in stone dedicated to St. Simeon, probably of the Pisan school and dated at the beginning of the 14th century. The 15th– century tombstone in the wall of the nearby portico, which depicts a praying bishop, is most particular.