New Antibiotics against Bacteria

There is decrease in
the resistance movement founded by the bacteria to combat different antibiotics
in the antibiotic list. More powerful weapon was designed by the scientists by
combining important properties of the different weapons used by natural defense
system of the organisms.

It was done to find an
antibiotic which can be more effective and novel. This new antibiotic can be more powerful as compared to the
previous antibiotics. There are number of such new antibiotics available in the
antibiotic list.

The first antibiotic is
magnetic weapon which is produced by all organisms as natural antibiotic. This
magnetic weapon or antimicrobial peptide is positively charged which is
attracted negatively by the bacteria just like a magnet. These two antibiotics
in the antibiotic list can exert antibacterial effects. The second antibiotic
used to make new antibiotic in the antibiotic list is a detergent like weapon
known as lipopeptide. It is produced
only by fungi and bacteria because of negative charge with
fungi target. There is fatty acid chain in the new antibiotic. This chain is
similar to the soap chain which can dissolve oils and dirt breaking fatty
membranes of fungi.

The scientists combined
different properties of the AMPs lipopeptides in the
antibiotic list thus forming new antibiotic synthetic lipopeptide
which as positive charge as well as ability to dissolve oils like soap. The
scientists were able to create new array of weapons by changing the sequence of
the positively charged amino acids and length of chain of fatty acids in the
antibiotic list. Some of these new antibiotics are active against fungi and
bacteria while other can target just one or other. New antibiotic synthetic
peptides were designed containing four amino acids as opposed to that found in
the natural forms.

These new antibiotics
will certainly open up new potential application range. This antibiotic is more attractive for drugs because of short
length of synthetic peptides. This new finding will be easier to use, less
prone to the resistance, cheaper to synthesize and it can also have the ability
to target large number of fungal and bacterial infections. The new antibiotics
were found to be very effective and powerful and are being added to the
antibiotic list more frequently. Research is also being made to find more and
more new antibiotics to make antibiotic list.