New Therapeutic Targets and Biomarkers: March 2018
Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database during March 2018. Therapeutic targets are defined as any protein, gene or other molecule...

INDICATION: Bacterial infection
Chimeric antigens against N. meningitidis fHbp and N. meningitidis porA could be used to develop vaccines against serogroup B N. meningitidis infection. The antigens were generated by using a soluble N. meningitidis fHbp...

Drug delivery
TECHNOLOGY: Nanoparticles
Sheath-like nanoparticles derived from bacteria could be used to deliver vaccine antigens to prevent infections. The sheaths consisted of tubular, heterodimeric structures of ClpV-interacting protein A (VipA) and VipB isolated from the secretion...