The function venue Le Montage in Lilyfield was heavily guarded with mounted police, officers on bicycles, riot squad, marine police and police vans barricading the event after several arrests were made at his Victorian event on Monday night.

NSW Police told SBS News five arrests had been made so far. Four people were arrested over breach of peace offences, one involved an alleged police assault, one for affray and another over failure to comply with police.

A few protesters were seen being handcuffed and carried away after clashing with police officers at the venue.

Several Yiannopoulos supporters were chased off by officers after brief conflicts with anti-fascists.

He was heckled as he entered the packed room of fans, journalists and the morbidly curious in Canberra, but there were no security issues.

The self-described "one-man wrecking crew" and "internet supervillain" was there at the invitation of Liberal Democrats senator David Leyonhjelm.

Protestors have been met with heavy police guard at Milo Yiannopoulos' Sydney event.

AAP

Fights broke out at Yiannopoulos' event in Melbourne on Monday, with police forced to use pepper spray.

Mr Yiannopoulos's speeches on university campuses in the US have sparked violent protests, and he was banned from Twitter last year amid a barrage of racist abuse directed at Ghostbusters star Leslie Jones.

Who is Milo Yiannopoulos?

33-year-old from Kent, England known for his alt-right views.

Was appointed technology editor for right-wing website Breitbart News in 2015, he has since stood down.

Was banned from Twitter in July 2016 for inciting abuse of others.

In 2017 he founded Milo Inc. dedicated to ‘destruction of political correctness’.