Synanceia is a genus of fish of the familySynanceiidae, the Stonefishes, whose members are venomous, dangerous, and even fatal to humans. It is one of the most venomous fish currently known in the world.[1][2] They are found in the coastal regions of Indo-Pacific oceans as well as off the coast of Florida and in the Caribbean.

Synanceia are primarily marine, though some species are known to live in rivers. Its species have potent neurotoxins secreted from glands at the base of their needle-like dorsal fin spines which stick up when disturbed or threatened.[3] The vernacular name of the species, the stonefish, derives from the stonefish's ability to camouflage itself with a grey and mottled color similar to the color of a stone.[4] Swimmers may not notice them, and may inadvertently step on them, triggering a sting. When the stonefish is disturbed, it may inject an amount of venom proportional to the amount of pressure applied to it.[citation needed]

Stonefish stings are both potentially lethal and extremely painful.[6] The two most recommended treatments include the application of heat to the affected area and antivenom. People have used hot water (at a temperature no lower than 45 °C (113 °F)) applied to the injured area which has been found to destroy stonefish venom, and causes minimal discomfort to the victim. For more extreme cases, antivenom has been used. Vinegar can be found on some Australian beaches where there are frequent cases of people stepping on these fish, as the vinegar is said to lessen the pain.[7]

Stonefish stings in Australia can cause envenomation and death if not treated. The stonefish is one of the most venomous fish in the world[8] and when stepped on by a human forces venom into the foot. Most stonefish stings occur as a result of stepping on the creature while it is less common for the fish to sting when it is picked up.[9] Stonefish stings can occur on the beach, not just in the water, with stonefish being able to stay out of the water for up to 24 hours. They often cannot be easily seen as they look similar to rocks or coral. Stonefish antivenom is the second-most administered in Australia.[10]

Aborigines know of the venom of the stonefish and have corroborees which involve re-enacting death from someone who trod on the fish. The Aborigines of Northern Australia and the Great Barrier Reef have different ways of preparing the fish for eating to avoid poisoning.[11]

After stonefish envenomation, the amount of anti-venom given depends on the number of puncture wounds from the stonefish spines.[12]

Though Synanceia are venomous and dangerous to human beings, they are actually consumed as food in some parts of Asia, including south Japan, south Fujian and Guangdong in China, and Hong Kong. Their venom is harmless after heating. In the Hokkien-speaking area, they are considered delicacies and good for health. The meat of Synanceia is white, dense and sweet, and the skin is also edible. They are usually cooked with ginger into a clear soup, and sometimes served raw as sushi or sashimi.[citation needed]