Lars Palmqvist research group

Lars Palmqvist

Acute myeloid leukemia (AML) is the most common form of acute leukemia and affects both children and adults. In children, this form of leukemia is associated with a much worse prognosis than the common form of childhood leukemia, acute lymphoblastic leukemia. Better understanding of the mechanisms behind this form of leukemia and improved treatment decisions are of outmost importance for the fighting of this disease.

The overall aim of our projects is to identify molecular mechanisms involved in the development of AML and novel ways of identifying and target leukemic cells in patients. Our clinical research is performed on samples from patients with acute myeloid leukemia, both children and adults. Pathogenic mechanisms for the development of this disease are studied in a murine bone marrow transplantation model. We also perform stem cell research on hematopoietic stem cells in human cord blood and mouse bone marrow. We believe that our investigations will lead to a better understanding of the development of malignant hematological disorders and to better risk stratification of patients with acute leukemia and ultimately to better treatment.