Fusion

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RSAG_03220

Uncharacterized protein (312 aa)

Predicted Functional Partners:

aroB

3-dehydroquinate synthase (363 aa)

0.777

RSAG_00583

Uncharacterized protein (261 aa)

0.725

RSAG_00177

Uncharacterized protein (878 aa)

0.689

ruvA

Holliday junction ATP-dependent DNA helicase RuvA ; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (202 aa)

0.668

RSAG_03433

Uncharacterized protein (228 aa)

0.664

ruvB

Holliday junction ATP-dependent DNA helicase RuvB ; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (334 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

RSAG_00177

RSAG_00333

RSAG_00177

RSAG_00333

Uncharacterized protein

Uncharacterized protein

0.566

RSAG_00177

RSAG_00583

RSAG_00177

RSAG_00583

Uncharacterized protein

Uncharacterized protein

0.618

RSAG_00177

RSAG_03201

RSAG_00177

RSAG_03201

Uncharacterized protein

Uncharacterized protein

0.553

RSAG_00177

RSAG_03220

RSAG_00177

RSAG_03220

Uncharacterized protein

Uncharacterized protein

0.689

RSAG_00177

RSAG_03322

RSAG_00177

RSAG_03322

Uncharacterized protein

Uncharacterized protein

0.674

RSAG_00177

ruvA

RSAG_00177

RSAG_00937

Uncharacterized protein

Holliday junction ATP-dependent DNA helicase RuvA ; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB

0.564

RSAG_00177

ruvB

RSAG_00177

RSAG_00936

Uncharacterized protein

Holliday junction ATP-dependent DNA helicase RuvB ; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing

0.620

RSAG_00333

RSAG_00177

RSAG_00333

RSAG_00177

Uncharacterized protein

Uncharacterized protein

0.566

RSAG_00333

RSAG_03220

RSAG_00333

RSAG_03220

Uncharacterized protein

Uncharacterized protein

0.622

RSAG_00446

RSAG_03220

RSAG_00446

RSAG_03220

Uncharacterized protein

Uncharacterized protein

0.606

RSAG_00583

RSAG_00177

RSAG_00583

RSAG_00177

Uncharacterized protein

Uncharacterized protein

0.618

RSAG_00583

RSAG_03220

RSAG_00583

RSAG_03220

Uncharacterized protein

Uncharacterized protein

0.725

RSAG_03201

RSAG_00177

RSAG_03201

RSAG_00177

Uncharacterized protein

Uncharacterized protein

0.553

RSAG_03201

RSAG_03220

RSAG_03201

RSAG_03220

Uncharacterized protein

Uncharacterized protein

0.589

RSAG_03220

RSAG_00177

RSAG_03220

RSAG_00177

Uncharacterized protein

Uncharacterized protein

0.689

RSAG_03220

RSAG_00333

RSAG_03220

RSAG_00333

Uncharacterized protein

Uncharacterized protein

0.622

RSAG_03220

RSAG_00446

RSAG_03220

RSAG_00446

Uncharacterized protein

Uncharacterized protein

0.606

RSAG_03220

RSAG_00583

RSAG_03220

RSAG_00583

Uncharacterized protein

Uncharacterized protein

0.725

RSAG_03220

RSAG_03201

RSAG_03220

RSAG_03201

Uncharacterized protein

Uncharacterized protein

0.589

RSAG_03220

RSAG_03322

RSAG_03220

RSAG_03322

Uncharacterized protein

Uncharacterized protein

0.616

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Network Stats

Network Stats analysis is still ongoing, please wait ...

Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: