Lizzy Caplan Talks Masters of Sex

The beloved, versatile actress (Children's Hospital, New Girl, Party Down) helps anchor Showtime's new drama, Masters of Sex, which premieres tonight at 10.

Caplan stars on the series as Virginia Johnson, a former nightclub singer who worked in 1950s and 1960s with Michael Sheen's Dr. William Masters on groundbreaking research into the world of human sexuality, helping to set off a revolution across the country.

What was it like to take on such a real-life role? The actress talked to TV Fanatic about the series at the Masters of Sex premiere party in New York City this week: