On October 22, the National Toxicology Program (NTP) published a draft review of fluoride's neurotoxicity concluding:
​"…fluoride is presumed to be a cognitive neurodevelopmental hazard to humans. This conclusion is based on a consistent pattern of findings in human studies across several different populations showing that higher fluoride exposure is associated with decreased IQ or other cognitive impairments in children."

FAN's director Paul Connett, PhD, says, "We hope that, when the National Academy of Sciences completes its peer review, NTP will raise the classification of fluoride to a 'known' from 'presumed' neurodevelopmental hazard to humans. Whether they do or not, the weight of scientific evidence in the NTP review should be sufficient to force an end to fluoridation."

The draft review comes at a time when the public appears is becoming rapidly awake and aware of the dangers of unregulated doses of ingested fluoride. In August, mainstream headlines reported a society-altering finding about fluoride. The American Medical Association’s journal on pediatrics (JAMA Pediatrics) published the second U.S. Government-funded study linking low-levels of fluoride exposure during fetal development to cognitive impairment. The observational study, entitled Association Between Maternal Fluoride Exposure During Pregnancy and IQ Scores in Offspring in Canada, was led by a team at York University in Ontario, Canada and looked at 512 mother-child pairs from six major Canadian cities. It was funded by the Canadian government and the U.S. National Institute of Environmental Health Science.

The scientists assessed fluoride exposure two ways. They measured fluoride in women’s urine samples during pregnancy. They also calculated fluoride consumption based on how much is in a city’s water supply and how much women recalled drinking. They found that a 1 mg per liter increase in concentration of fluoride in mothers’ urine was associated with a 4.5 point decrease in IQ among boys, though not girls. When the researchers measured fluoride exposure by examining the women’s fluid intake, they found lower IQs in both boys and girls: A 1 mg increase per day was associated with a 3.7-point IQ deficit among both genders.

Fluoride’s ability to damage the brain is one of the most active areas of fluoride research today. Over 400 studies have found that fluoride is a neurotoxin (a chemical that can damage the brain). This research includes:

Over 200 animal studies showing that prolonged exposure to varying levels of fluoride can damage the brain, particularly when coupled with an iodine deficiency, or aluminum excess;

Based on this accumulating body of research, several prestigious reviews — including a report authored by the U.S. National Research Council, a meta-analysis published by a team of Harvard scientists, a review published in The Lancet, and a 2017 U.S.-funded 12-year study that found a link between fluoride in the urine of pregnant women and lower measures of intelligence in their children — have raised red flags about the potential for low levels of fluoride to harm brain development in some members of the population.