Structural Biology

The Structural Biology Group uses high resolution X-ray crystallography and cryo-electron microscopy to understand the atomic structure of proteins involved in the production of biofuels and bioproducts. Atomic resolution structures, when combined with genomic and biochemical data, can provide a mechanistic understanding of enzyme activity and specificity. JBEI researchers use this information to help optimize enzymes for the production of biofuels and bioproducts, improving activity and modifying substrate specificities and product profiles.