The pump itself should make a little noise, (after all, it is circulating liquid). When the pump is first connected, there will also be a little noise for ~1 min as some of the air works its way through the system. Ideally, Q-fan should be disabled for the CPU fan, since the pump uses its own sensor to regulate fan speed. I hope this helps...

if that setting and change does not work, please try removing the radiator block..when it's cold, and shake it for a little bit have air bubble to circulate around actual radiator and see if the noise lessen.

Also, please make sure all fan assembly is tightly screwed into the framing of the case...the make also occur during certain RPM of the pump and fan.

Hey what happened I thing Im having the same problem
and its just pissing me off I feel like have a of those old pumps for aquariums ..
or super noisy HDD like the noise an hdd makes when its starts just louder and 24/7