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French tourist Aurelie Lhorme has gone missing while driving along the South Australian coast. Photo: Facebook

French tourist Aurelie Lhorme arrived in Australia this month and set off on a road trip along the country's rugged southern coastline.

The 30-year-old had travelled to Australia previously, but on this trip hoped to find a job and possibly stay for an extended period of time.

But police fear Ms Lhorme's adventure may have taken an ominous turn on Saturday night, on an isolated road about 10 kilometres from the Head of the Bight Whale Watching Centre, near the Nullarbor Plain in South Australia.

Aurelie Lhorme, who was last seen on Saturday Night near the Head of the Bight Whale Watching Centre in South Australia. Photo: Facebook

Parked on the side of that road they found Ms Lhorme's grey Toyota sedan. The vehicle was locked and inside officers found Ms Lhorme's passport, wallet and phone. Ms Lhorme, from Toulouse in southern France, was nowhere to be found.

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A search party, including an Aboriginal tracker and a police plane, could not find any trace of her on Sunday afternoon.

As the search resumed on Monday morning, police revealed that a number of people travelling in a motorhome may hold vital clues about the mysterious disappearance of the tourist.

Aurelie Lhorme, who has gone missing after travelling to South Australia. Photo: Facebook

"Police are ... interested to speak to the occupants of a Jayco motorhome that was parked at the Head of Bight on Saturday night, near to where Aurelie had left her car, and may have had some contact with her," South Australia police said.

They said a staff member at the Head of Bight Whale Watching Centre, west of Ceduna, had spoken to Ms Lhorme early on Saturday night and it appeared she was planning to sleep in her car.

The following morning, the staff member noticed the car was parked in the same spot, but there was no trace of Ms Lhorme.

The search resumed on Monday morning using a police plane, local patrols and State Emergency Service volunteers. Officers from South Australia Police's special tasks and rescue team are co-ordinating the search and have travelled to the area from Adelaide.

At 2.20pm, police said they were searching at the base of a cliff after unconfirmed reports of a body being sighted.

On her Facebook account on April 4, Ms Lhorme wrote to a friend that she was in France but was about to fly back to Australia.

" . . . im flying back to australia next week, back to work, i ll find hopefully," she wrote.

The whale watching centre says the area is known for its sense of isolation.

"At this unique geographical spot, a mini-desert of towering sand dunes meets a sheer line of 90m limestone cliffs," the website says.

"In the sheltered waters of the bay below, Southern Right Whales congregate en masse to give birth to calves."

South Australia police have urged anyone with information about Ms Lhorme to contact the police assistance line on 131 444.