Molecular motion influencing the absorption spectrum of a chromophore in liquid is theoretically described by a quantum mechanical time correlation function. In the present paper, we developed a theoretical method to calculate such a quantum mechanical time-correlation function from a classical time-correlation function using semi-classical approximations. The calculated time-correlation function was combined with the second order cumulant expansion method to calculate the absorption spectrum of nile blue in acetonitrile. Reasonably good agreement with experimental spectrum was obtained. From the comparison with experimental spectrum, we concluded that the time scale of solvation dynamics of the system should be longer then 1ps and the first shell of solvent is the major contribution to the solvation dynamics.

on-line system for preconcentration and separation of lead(II) is presented. The method is based on the complex formation of Pb(II) with adsorbed Methyl thymol blue on activated carbon. The conditions of preparing the solid phase reagent and of quantitative recovery of Pb(II) from diluted solutions, such as acidity of aqueous phase, solid phase capacity, and flow variables were studied as well as effect of potential interfering ions. After preconcentration step, the metal ions are eluted automatically by 5 ml of 0.5 M HNO3 solution and the lead ions content was determined by flame atomic absorption spectrometry. Under the optimum conditions, the lead ions in aqueous samples were separated and preconcentrated about 1000-fold by the column. The detection limit was 0.001 g mL-1. Lead has been determined in river and tap water samples, with recovery of 98 to 102%.

Simple Keggin type tungsten and molybdenum heteropoly acids, H3PW12O40 and H3PMo12O40, were usedas water-tolerant catalysts for the oxidation of alcohols with 34% hydrogen peroxide in normal drinking water. Accordingto our findings, H3PW12O40 may be used as a simple, effective, and cheap catalyst for this type of transformation in nor-mal drinking water with excelent yields. Efects of diferent solvents at 25-80oC and changing concentration of catalystand substrate on the reaction progress were also studied.

purpose of the study was to synthesize new series of 5-cyano substituted pyrimidine analogues with different substitutions at N1 and 6 positions and to evaluate them for antibacterial and antifungal activities. The desired compounds were synthesized by tertiary condensation of ethylcyanoacetate, substituted thioureas and suitable aldehyde in presence of potassium carbonate using MORE technique. The antibacterial and antifungal activities were evaluated by cup plate method in the concentration of 25 mg. The zone of inhibition was measured in mm. All the compounds have shown significant antibacterial and antifungal activities. The maximum activity was shown by P1 and P5 against S.aureus and E.coli respectively, while P6 has shown significant activity against all types of microorganisms. The compound P8 has been found to be significantly effective against C. albicans. Norfloxacin and griseofulvin were used as standards to compare the activites of synthesized compounds. It is concluded that analogues containing p-hydroxy, p-methoxy substituted phenyl moiety at 6 position have been found to be more potent against gram-positive microorganisms, while analogues lacking these substituents on phenyl moiety possessed gram-negative activity. The compounds having p-dimethylamino substituent on phenyl moiety at 6 positions have shown moderate activity. Further, only fluorine containing analogue at N1 position was found to possess appreciable antifungal activity. This suggests that electron donating substituent on aryl moiety as well as electron withdrawing substituent at N1 plays important role in determining potency of the compounds.

cyclization of primary arylselenocarboxylic amides with a-bromoketones afforded a variety of new 2,4-diaryl-1,3-selenazoles. Halogenation of the 2,4-diaryl-1,3-selenazoles with chlorine, bromine and iodine gave the new 1,1-dihalo-2,4-diaryl-1,3-selenazoles in good yields. Antiviral activity of some 1,1-dihalo-2,4-diaryl-1,3-selenazoles has been tested against AIDS virus (HIV-1 and HIV-2). They showed some bioactivity against HIV-1. All compounds were characterized by their elemental analysis, 1H NMR and mass spectroscopic data. The crystal structure of 2-(3,4-dimethoxyphenyl)-4-(4-bromophenyl)-1,3-selenazole displays the molecular configuration.

A simple synthetic strategy is described for one-pot synthesis of 5,7-diaryl-4,4-dimethyl-4,5,6,7-tetrahydropyridino[3,4-d]-1,2,3-selenadiazoles (11-15) in the presence of NaHSO4.SiO2 as a heterogeneous catalyst in dry media under microwave irradiation.Key words: One-pot synthesis, 3,3-Dimethyl-2,6-diarylpiperidin-4-one; 1,2,3-Selenadiazoles; Selenium dioxide; NaHSO4.SiO2 Heterogeneous catalyst.

facile and efficient method for the preparation of Z-aldoximes is improved by means of H3PMo12O40 catalyst in solvent-free media. The major advantages of this method are: operational simplicity, low catalyst loading, selectivity, mild reaction conditions, short reaction times and excellent yields. The recovered catalyst could be used in new attempts without any purification.

are nanometer or micrometer scale vesicles that can be used as drug delivery carriers. However, plain liposomes are plagued by rapid opsonization, making their circulation time in bloodstream be shortened. In this study, model protein, bovine serum albumin (BSA)-coated liposomes were prepared by coating cationic liposomes with BSA molecules at higher pH than isoelectric point of BSA. The BSA molecules coated on the liposomal surface were denatured by thermal treatment at above 60oC. While both plain and cationic liposomes had about mean particle diameter of 1041 nm, BSA-coated cationic liposomes (BCL) had mean particle diameter of 1091 nm. Encapsulation of model drug, doxorubicin (DOX), in liposomes were carried out by using remote loading method and the loading efficiency of DOX to liposomes was about 90%. The mean particle diameter of BCL did not increase in blood plasma and adsorption of plasma protein was much less than plain or cationic liposomes. These results suggest that BCL can be used as a long-circulating liposomes in bloodstream.

The photocatalytic degradation of a textile diazo dye in aqueous solution has been investigated under Solar and UV-A light. The effect of various parameters such as concentration of dye, amount of catalyst and pH on the degradation of dye has been studied. Addition of hydrogen peroxide, ammonium persulphate and isopropanol strongly influences the degradation rate. Kinetic analysis of photodegradation reveals that the degradation follows approximately pseudo first order kinetics according to the Langmuir-Hinshelwood model. Carbon dioxide, nitrate and sulphate ions have been identified as mineralisation products. The photocatalyst ZnO was found to be more efficient in UV-A light than in Solar light.

The purpose of this study was to investigate the types of conceptions of mixing phenomena related to dissolution and diffusion in high school students. The subjects of the investigation consisted of 108 students who took chemistry I course at 11th grade and 29 students who took chemistry II course at 12th grade. For this study, it was found that the many students had the alternative conception that chalk didn`t dissolve in water because chalk was a nonpolar material. Most of the students understood the phenomena which carbon tetrachloride and water will not mix as the attraction conception. But many of the other students understood the phenomenon as characteristic of the materials such as difference of density. Many of the students understood the phenomenon of mixing ethanol and water constantly as ‘Attraction conception`. The phenomenon which is mixed ink and water was just accepted by the most students as the spreading of ink in water without understanding the reason of mixing. The phenomena of mixing iodine and carbon tetrachloride was understood as ‘Space conception` or ‘Attraction conception`. It could be inferred that the diverse alternative conceptions related to dissolution and diffusion phenomena were generated by the absence of entropy concept. Therefore, the explanations of science textbooks related to dissolution and diffusion phenomena need to change for students to understand them correctly.

In this study, preconceptions held by chemistry major secondary school science teachers were searched in relation to explanations of water evaporation phenomena with phase equilibrium diagrams. 25 chemistry major science teachers were selected to complete questionnaires developed in this study and 6 among of them were selected to participate in follow-up interviews. Among these, 10 participants were selected for an evaluation of the change of their preconceptions through lessons developed in this study. From the results, it was found that many teachers believed that the phase equilibrium diagram could not explain water evaporation phenomena. They also thought that there was no relation between vapor pressure and the vertical axis of the phase equilibrium diagram. However, after the lessons in earth science, they recognized that the vapor pressure curve of the phase equilibrium diagram could be explained by adopting a saturated vapor curve. Because they had known the process of application the conceptions of saturated situation, nonsaturated situation, process of equilibrium movement in saturated vapor curve. They could understand natural phenomena such as evaporation with the phase equilibrium diagram through a change in their conceptions as guided from science lessons integrating earth science and chemistry.

The purpose of this study was to identify the actual conditions of operation in school and investigate the perceptions of science teachers and students regarding the 7th elective-centered curriculum of high school science subjects. For this study, a questionnaire survey was conducted for the selected subjects including 127 high school science teachers and 763 high school students in their third year who had experienced the 7th elective-centered curriculum. As a result of the study, concerning the way to present the elective subjects of science, many cases were the alternative way and the group-elective way in humanity courses while natural science courses had the alternative way and the free-elective way in most cases. In other words, in many cases, the right of elective was given within a limited range. The result of the investigation on science teachers` perceptions on the elective-centered curriculum was that negative views dominated as a whole. Especially, earth science teachers showed the most negative attitudes. The number of biology and chemistry teachers who supported students` right to opt subjects were lower than that of physics teachers and earth science teachers who were against it. To help students make a right choice, many viewed that the system of the college Scholastic Ability Test should be complemented in order to prevent any disadvantage to each elective subject or that it was necessary to have systematic and realistic career education. As the result of investigating the perception of high school students in their third year regarding the elective-centered curriculum, they were usually not very satisfied with it. As the reason for it, many said the selection right was limited. Many others also expressed that there were lack of public relations and education on subjects and careers. Based on these results, limits still exist in accepting all demands although there are a lot of efforts made to smoothly adjust supply and demand of science teachers as well as students` electives in the field of school. It is considered necessary to come up with counterplan and complements to prevent basic science from being neglected or lower academic achievement in the subject of science from happening, and at the same time to harmoniously deal with supply and demand of science teachers as well as the issues of students` demands given the actual conditions of school.