The Pendleton County Emergency Management Agency reported one tanker was leaking a liquid, but the substance was not immediately identified. A CSX Transportation representative said four cars were carrying sulfuric acid and that no hazardous materials leaked in the derailment.

CSX said the cleanup process takes time since they must monitor air quality to make sure nothing leaks or becomes a danger as they put the 24 cars back on the tracks or pull them away from tracks.

There were no injuries in the incident.

All roads into town ended up closed. Residents who live nearby were asked to stay inside and keep their windows shut. The Red Cross offered assistance to people who evacuated from their homes.

By 3:30 p.m., the shelter-in-place order lifted and most streets reopened, except those near the site of the incident.

The Federal Aviation Administration placed a flight restriction over Falmouth just after the train derailed.

Sheriff Craig Peoples said he did not know what, specifically, the train was carrying.

Inspectors from the Federal Railroad Administration were headed to the scene Wednesday afternoon. The National Transportation Safety Board did not send any representatives to Falmouth but was monitoring the situation, a spokesman said.

According to Pendleton County emergency dispatchers, the cars derailed near Park Street at 10:30 a.m. The train was traveling from Cincinnati to Atlanta, according to railroad company CSX.