Abstract

Reactions to liver extract, usually clearly of an allergic nature, have been reported by numerous authors1-35 since 1931. These 35 articles record a total of only 50 patients experiencing reactions from liver extract by injection. The condition is by no means so rare, however, as the above number would indicate. In this article we are reporting 11 additional cases, four seen personally and seven whose detailed histories were given us by two of our colleagues (table 1). Dr. Guy Clark of the Lederle Laboratories wrote us that "over a period of several years we have received approximately 30 reports of