11317R 1182deIGAG S555R A337D W34IR

Figure 20-1. Schematic representation of the MEN1 gene indicating the intron-exon organization, as well as the relative location, type, and distribution of germline mutations characterized in patients with MEN1. Functional domains of menin that interact with JUND,SMAD3,and NFKB are indicated below the gene map. (From Wautot V,Vercherat