Moyes has been manager at the club for less than a season after replacing Sir Alex Ferguson in the summer.

The club confirmed on Tuesday morning on its Twitter account that Moyes had “left the club” after less than a season in charge. Ryan Giggs is favourite to be named interim manager.

Moyes endured a miserable time in charge, with Sunday’s 2-0 loss at his former club Everton the latest setback.

A statement from the club, released at 8:30am, read: “Manchester United has announced that David Moyes has left the club.

“The club would like to place on record its thanks for the hard work, honesty and integrity he brought to the role.”

A series of reports first surfaced yesterday afternoon that the Scot’s ill-fated reign as Red Devils boss would shortly be brought to an end.

Reports cited the 2-0 defeat to Moyes’ former club Everton as the final straw for the Glazer family, which owns the club. United, who won the Premier League last season in Sir Alex Ferguson’s final campaign in charge, are seventh in the table this time around.

The loss at Goodison Park was United’s 11th of a wretched title defence and killed off any last hopes of a return to the Champions League next season with the gap to fourth-placed Arsenal now too big to bridge.

United were knocked out of this season’s Champions League by holders Bayern Munich in the last eight, having led briefly in both legs.

They were eliminated from the FA Cup at the first hurdle by Swansea and were knocked out of the Capital One Cup at the semi-final stage by Sunderland.

United will end the season with their worst points total in Premier League history. They have failed to qualify for the Champions League for the first time in two decades.

TIMELINE

David Moyes was sacked on Tuesday after less than 10 months in charge of Manchester United.

Here, are the lowest points from Moyes’ dismal short reign at the Old Trafford helm.

September 1 - United suffer first defeat under Moyes as Daniel Sturridge gives Liverpool victory at Anfield. Wayne Rooney misses the game with a nasty head wound after being kicked in the head accidentally by Phil Jones in training.

September 22 - Hammered 4-1 at Manchester City. This time Robin van Persie is absent with a thigh injury.

September 28 - United lose 2-1 at home to West Brom, ending the Baggies’ 35-year wait for an Old Trafford triumph.

October 19 - Concede last-minute Adam Lallana equaliser against Southampton at Old Trafford.

December 4 - Bryan Oviedo scores four minutes from time as Moyes’ former club Everton end their 21-year wait for an away win over United.

December 6 - Rio Ferdinand criticises Moyes’ policy of leaving it late to pick his teams, claiming on BT Sport: “It turns you into a madman.”

December 7 - Yohan Cabaye gets the only goal as Newcastle win at Old Trafford for the first time since 1972.

December 10 - Van Persie suffers thigh injury taking a corner against Shakhtar Donetsk, and is ruled out for seven weeks.

January 1 - Rooney plays in the defeat by Tottenham but is then ruled out for four weeks with a groin injury.

January 5 - Swansea win at Old Trafford for the first time as Wilfried Bony’s late goal sends United out of the FA Cup at the third-round stage for only the second time in 30 years.

January 7 - Defeat in Capital One Cup semi-final first leg at Sunderland means a third straight loss for the first time since May 2001.

January 19 - Skipper Nemanja Vidic is sent off as United crash to defeat at Chelsea.

January 22 - United beat Sunderland 2-1 in the Capital One Cup semi-final return leg thanks to Javier Hernandez’s last-gasp effort in extra-time but come off worst in an awful penalty shoot-out, with only Darren Fletcher scoring from their five kicks.

February 1 - Stoke end their long wait for a win against United. Charlie Adam’s double gives them their first since 1984.

February 7 - Vidic confirms he will leave at the end of the season.

February 9 - United come from behind to lead bottom side Fulham at Old Trafford, but Darren Bent’s stoppage-time equaliser settles a 2-2 draw to deny the hosts all three points. Moyes describes the result as being “as bad as it gets”.

February 25 - It proves gruesome in Greece for United in the Champions League last 16 as a poor performance sees the Red Devils beaten 2-0 by Olympiacos in Piraeus.

March 16 - Another day United will want to forget in a hurry as two Steven Gerrard penalties and a Luis Suarez strike earns Liverpool a crushing 3-0 win at Old Trafford. It could have been even worse for Moyes’ men as Gerrard also hit the post with another penalty.

March 25 - United lose 3-0 to bitter rivals for the second consecutive home league game as a brace from Edin Dzeko and a late strike from Yaya Toure hands Manchester City a derby double over their city rivals. The result ensured United were guaranteed to end the season with their lowest points total in Premier League history.

April 9 - Despite an encouraging 1-1 draw in the first leg and taking the lead through Patrice Evra, the Red Devils go down 3-1 to defending champions Bayern Munich in the second leg of their Champions League quarter-final at the Allianz Arena.

April 20 - Moyes’ return to Goodison Park is turned into a nightmare as a Leighton Baines penalty and a goal from Kevin Mirallas hand Everton a 2-0 win, a result which means United cannot qualify for the Champions League.

April 22 - Moyes is sacked by United.

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If we have to play Manure twice a season (and unfortunately we do), this is probably the best time to do it. In the Boardroom they have Americans who know nothing about English football and care even less; on the pitch they have the likes of Wayne Rooney who will only extend his contract if the club pay him every year the same amount as it costs to build a small hospital and he will be busy right now scratching his funny little empty head wondering how to spend it; in the dug out they have appointed a serial womaniser who will be much too busy eyeing up the WAGS to worry about team selection, tactics and that sort of stuff. We'll still lose, of course, because that's what Norwich do nowadays, but at least it's good to be reminded that Norwich is a decent football club compared with that gigantic pile of.........well, Manure.

I know this news doesn't really interest City fans but it did give us five minutes of radio magic this morning. On 5 live a small panel of opinions and Terry Christian (a real fan from years ago) was getting a bit prickly. On they bought Robbie 'Lily' Savage who gave us 20 odd seconds of populist waffle when Christian tore into him. Nearly knocked him of his seat. A few minutes later Lily came back with his 'as an ex-pro' superiority only to be savaged again by Christian. I have been waiting two or three years to hear this.

Gary Lineker was right, it is bonkers sacking a manager with a handful of games left. In the case of Man U, it's slightly different as their season is over. But the whole Premier league has gone mad, no manager is given enough time any more. Norwich have a better chance of winning now, I think an upset is on the cards...

Agree LYB. Play as ive witnessed us play against Fulham & Liverpool and we stand a chance. I hope like you Man Utd struggle to get motivated. However if Ryan Giggs is placed in charge im sure the fans will be behind him 110% even though hes an unknown in manager terms and im also sure they will be hoping for an instant turn around so they can fully blame Moyes etc.

Their season is over, nothing to play for now other than individuals wanting to get attention for the World Cup, so it really does not make any difference who is in charge. The Grim Reaper sitting behind Moyes was a nasty touch. On the other hand we have everything to play for.

Really looking forward to this weekend's game. Whoever the manager is, the fact is that Man U can't hit the Champion's League and can't be relegated, so Giggs is going to have a hard job to get them seriously motivated. If we also play to the levels we did for the most part against Liverpool, we've got to be in with a good chance.

The media will react differently to Moyes' sacking because the circumstances are different. First Moyes is perceived to be a huge failure, Hughton less so. Second Man U have nothing to lose so it is not a gamble, Norwich have everything to lose so it was a big gamble.

Well I guess this is one of the biggest News event of the season so far. I had a feeling there were going to be a few more twists in store this season. Hopefully Norwich City are not done yet ! After the second half showing against Liverpool - City did what we have been waiting for all season - played exciting attacking football and in fairness they played (champions in waiting) Liverpool completely off the park for long spells. We won that second half well and it should have been 3-0 or more to City. Manure will now be in a complete spin and turmoil with Moxies sacking and the press will feed on this all week. Lets go up there and give Giggs's side a damn good thrashing ! OTBC

What? A man with no premiership management experience being put in charge of a team at this stage of the season!
No doubt Gary Lineker will brand the decision 'bonkers' and the national media will condemn the Man U board.

Interesting that Man Utds Board did not shy away from a hard decision. I think this news does make our next fixture more difficult, Utd will be eager to prove it was Moyes, not them who was responsible for the poor results.. A huge test for Neil Adams to produce a side prepared for this battle.

I think timing is more to do with other clubs eyeing potential candidates and not wanting to miss out. This could work either way for us but we know this is not the greatest ManU team so we have a chance. Sometimes it's just not the right fit - I think we can relate to that....

I wonder if the national press will be as quick to condemn Giggs appointment as they were to condemn Neil Adams appointment my guess is they will not because this is Man.U and what about the motley crew at MOTD biased as ever no doubt

Well you can put as much lipstick as you like on a pig and it is still a pig. Giggs in charge might not give the lift as they know it isn't going to be him in charge going forward. Big chance for the Yellows - Carpe diem! All we need is a point to give Fulham and Cardiff something to think about. Sunderland might be more tricky as they have a better goal difference. Got my tickets this morning for the theatre of dreams......

If we now fail to take three points from Old Trafford, I think we need to complain to the FA as the other teams around the bottom were allowed to face a weak manager! I really cannot see the point in sacking him at this stage as the club are safe but cannot qualify for the Champions League so what could be achieved by this move.

Cannot see how this could be good news for us because if there were problems in the dressing room they are likely to go with David Moyes. We know how a change of manager can galvanise players even if only in the short term. I am sure Moyes is a good coach and will there will be big clubs who will be eyeing him.