While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.

There are new CBD companies coming online every week – these span the range from truly awful to really great. So how to choose the best? The quality of the CBD oil itself is obviously the most important factor – and many companies do take the quality of their products seriously. To reward those companies, we gave more weight to the quality of the product than any other category.

I wana take a minute to thank Lazarusnaturals for such great products. I have been suffering from ******,***** and ***** for years and have not been able to find relief from my pain medication,I know I’ll never be pain free as long as I’m breathing but CBD is pretty damn close to giving me my life back an being 90% pain free! I didn’t expect much from the CBD oil cuz there isn’t any THC (psychoactive) in it so I wasn’t getting excited lol but guess what?!! I’m super excited cuz this stuff works. Don’t knock it til you try it,if you suffer from pain do yourself a favor and order some CBD oil I promise you it will take the edge off.Im ordering my 3rd bottle now cuz this stuff works better then pain pills if you’re suffering from pain.

It sounds like the title of a children’s book, but like so much else that you learned in kindergarten, it’s true. Everyone’s body is different – but everyone’s endocannabinoid system is really unique. For reasons we don’t fully understand, receptors in the endocannabinoid system don’t respond predictably to cannabinoids from person to person. This lack of a predictable response makes standard dosing tricky.

It was previously believed that CBD in its isolated form was more potent and concentrated than full spectrum CBD; however, in 2015, the theory was debunked by a study from the Lautenberg Center for General Tumor Immunology in Jerusalem. In the study, researchers administered full spectrum CBD and CBD isolate to two different groups of mice. When comparing the data of the two groups, the results proved that the group administered with full spectrum CBD were provided with higher levels of relief. Furthermore, the study demonstrated that full spectrum CBD continued to provide relief as the dose increased, while CBD Isolate did not provide the same effect when there was an increase in dosage.