Born in Decatur, Indiana to Lawrence (local photographer) and Marie Anspaugh, he has a younger sister, Jane. He was married from 1974 to 1988 to cruise line sales manager Tamara Kramer.[3] They have a daughter, Vanessa. Anspaugh married actress Roma Downey on November 24, 1995.[4] The couple had a daughter, Reilly Marie, on June 3, 1996. In 1997, Anspaugh was clinically depressed and was treated at a rehabilitation clinic, which ultimately led to a breakdown of his marriage. Downey filed for divorce in March 1998, with it being finalized later that year.[5] After living in California for three decades, in June 2014 Anspaugh relocated to Bloomington, Indiana.[6]