Additional data file 4.

Between-sample normalization. A. Shown are data normalized based on spike-in controls
for the same miRNAs and factors as in Figure 3 in the main text. B. miRNAs and factors with at least one association at adjusted
p < 0.01 based on data normalized using spike-in controls. All miRNAs thus identified
were also identified after sample median centering with the exception of miR-152,
which was found to be associated with all three factors at p < 0.05 (Additional data
file 18). Heatmap colours reflect relative miRNA expression. The expression values
for a given sample group of interest were summarized by their mean. Brackets in the
left margin indicate members of the same miRNA family. Significance levels are indicated
in the right margins: * adjusted p < 0.05, ** adjusted p < 0.01, *** adjusted p <
0.001. Abbreviations for subtype: B = Basal-like, H = HER2+, LA = Luminal A, LB =
Luminal B, N = Normal-like.