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Dr John VilesI have an active research program studying protein misfolding associated with amyloid formation in neurodegenerative diseases such as Alzheimer's. My team uses a range of biophysical techniques to study the fundamental process that influence neurotoxic oligomer and amyloid plaque formation. Approaches include, bimolecular spectroscopies, including NMR, CD, IR and EPR to study protein structure, misfolding and stability.