In my preparation I'm trying to decide whether, if available at 8, I would take Cam Newton/Matt Stafford and then at 20 take best available WR/RB (or Gronk) or if I should take a top RB (Arian Foster or Ray Rice) at #8 and then counter with a QB like Schaub/Ryan/Eli/Romo in the 3rd or 4th round.

Assuming there is no really wonky scoring or lineup settings in the league, I would definitely go with option "B"