U2 concert ends early after Bono loses voice in Berlin

However, Bono never returned to stage with his bandmates - Adam Clayton, Larry Mullen and The Edge - releasing a message shortly afterwards, revealing they were seeking "medical advice".

The Irish quartet kicked off their eXPERIENCE & iNNOCENCE Tour in Berlin's Mercedes-Benz Arena last night - but the band's second show in the same city came to an abrupt end as the frontman lost his voice onstage. Something has happened and I think we can't go on.

The band said that they don't know what happened, but they're taking medical advice on the issue.

For the second time since 1989, U2 has had to cancel a concert partway through after Bono's voice failed, reports E! "As always, we appreciate our audience's understanding and all our fans" support in Berlin and those who travelled from afar.

"I've seen a great doctor", the singer said in a statement, adding that he was "happy and relieved that anything serious has been ruled out".

News that the singer was struck mute on stage in Berlin right at the start of his tour has therefore caused much amusement, with Labour Leave activist and trade union leader Paul Embery quipping: "There is a God".

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