Mouse problem

My usb mouse is connected, it's led is on, but it's not moving the cursor at all.
I tried unplugging and plugging it in every usb port I have but still not working.
Strangely keyboard 100% works and usb drive works too
Help me.....
I tried another mice that's 100% working on my other computers and they all won't work.
What should I do?

I would have a look in 'Device Manager' at the line 'Mice and other pointing devices'
Click the small arrow to the left of that line, to get the next line to show, below it.
Right click on that, and choose either 'update driver' or 'Uninstall' and then reboot your pc, with the mouse connected, and Windows should install the driver for it again.
I'm assuming this is a Microsoft mouse, if another type it might need it's own driver which should have been supplied with it, but it would be very unusual not to work in Windows at all, whatever the maker.

You might have a quick way of switching your touchpad on or off.
You might have a special function key to do this, check the number keys and function keys for a square touchpad symbol, then you would press Fn F6 or Fn F7, or whatever the symbol is on.
The touchpad symbol is a square shape with a line at each side;
eg; I [] I