Human head transplant pitch by Italian neurosurgeon Sergio Canavero

Human head transplant. An Italian neurosurgeon’s project to undertake the first human head transplant has received a sceptical welcome in the United States, where he made a pitch to donors and fellow scientists.

Sergio Canavero, who leads the Turin Advanced Neuromodulation Group, first announced his project in 2013, saying at the time that such a procedure could be possible as soon as 2016.

But this timeline seems extremely unlikely given the numerous obstacles and gaps in knowledge.

Dr Canavero made a 2.5-hour presentation at a conference of the American Academy of Neurological and Orthopedic Surgeons in Annapolis, Maryland. It was there he met for the first time a man who has volunteered for the world’s first head transplant.

Russian-born Valery Spiridonov, 30, suffers from Werdnig-Hoffmann disease, which is a progressive and incurable wasting ailment. He was among the 150 conference participants.

Invited to speak at the start of the conference, Dr Canavero described at length how he would mend a severed spinal cord — a crucial factor in any such surgery — and described advances in the field, especially on animals.

The secret was to use a nano blade to cut the cord, then polyethylene glycol and an electrical current to accelerate the reconnection of severed nerve fibres, he said.

But he admitted his knowledge was incomplete and did not go into much detail about the profusion of other major problems that could be expected with such an unfathomably drastic operation.

Among those issues is how to maintain and restore blood flow to the brain, or how to reconnect the parasympathetic nervous system, a key component of an organism’s automatic functions.

Transplant project likened to moon mission

Marc Stevens, an orthopedic surgeon from Smithfield, North Carolina who was attending the conference, said Dr Canavero’s presentation was intriguing but more research should be done on healing spinal cord injuries instead of attempting a head transplant.

Case Western Reserve University neurosciences professor Jerry Silver cautioned that spinal reconnection science touted by Dr Canavero was far from ready, noting the difficulties involved in reattaching the vagus nerve, which controls a variety of functions including digestion and heart rates.

At the end of his presentation, Dr Canavero asked his US peers for help — both with the science and the cash needed for the project.

“I did my homework and now I am asking you to help,” he said.

“Let’s suspend all judgement. What you have been taught is wrong.

“I need your help and I need your assistance. Be Americans.”

Likening his project to former president John F Kennedy’s Apollo mission to send men to the moon in the 1960s, he called on “billionaires like Bill Gates to give money for this project”.