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Author

Kumaran Elumalai

Date of Issue

2014

School

School of Physical and Mathematical Sciences

Abstract

Abstract
Activation of alkynes for hydroamination reactions have been studied with the iridium and rhodium dimeric complexes [Cp*MCl2]2 (M=Rh or Ir). The reaction of [Cp*IrCl2]2, 1a with terminal alkynes and anilines afforded a variety of iridium amino-carbenes, whereas the rhodium analogue 1b gave a range of metallacycles. In the presence of additives, 1b was found to catalyse the hydroamination of alkynes with anilines to afford ketimines or 1,2-dihydroquinolines. Similarly, 1a could catalyse the hydroamination of 2-alkynylanilines to yield 2,2’-biindoles or indoles. The pathways for these reactions have been studied using a combination of experimental and computational methods.