8 Responses to “Metafolin Knock Offs – Caution”

I have been taking Thorne 5-mthf 5mg for several months; I developed a pink rash that is extremely itchy. I read an article you wrote about folate causing a rash and would like to confirm exactly what rash you were talking about. Could this reaction be caused by a “fake” folate and which folate should I be taking or did this rash mean that I am allergic to folate. Lastly I am finding it extremely difficult to find a MD in my area who is knowledgeable or willing to learn about A1298C to help me and my family

Hi Mary – A rash can be a side effect of taking 5-MTHF. I cannot speak to the quality of this specific Thorne product, but they are a well-respected brand. It is possible that you are taking too much and/or too often. See this post addressing Methylfolate Side Effects (http://mthfr.net/methylfolate-side-effects/2012/03/01/).

More doctors are completing Dr. Ben’s training everyday. You can check the Physician Directory (https://seekinghealth.org/physician-directory/) to look for a practitioner in your area. If there are none in your area, there may be some who are willing to do phone consults or can point you in the right direction.

Hello Dr. Ben. I recently filled a script for a generic version of L-Methylfolate that I want to ensure is legitimate. The package calls it “L-Methylfolate Forte 7.5 mg” and the insert label says that each capsule contains 7.5 L-Methylfolate as Metafolin AND 90.314 mg Algae-S powder (Schizochytrium). It is manufactured by Nestle Health Science, distributed by Breckenridge Pharmaceutical. Is this a true generic for Deplin? If so, why is everyone paying the Deplin prices? Thank you.

The ingredient in those is probably Quatrefolic (glucosamine salt of (6S)-5-methyltetrahydrofolate), which appears to be as effective as Metafolin. At least the EFSA (Europian Food Safety Authority) thinks so. You can search the paper by EFSA. It’s somewhere on their website. Use google.

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