What is Peptide Therapy?

Peptide therapy is an area of medicine that represents the future of the Integrative Medical Practice. It has very specific applications in a variety of different human tissues. Recently, public interest has increased for patients aspiring to achieve optimal health.

Our practice is one of the only clinics with A4M peptide certified practitioners in the Eastern United States. We have been utilizing peptides since March of 2014. Our practice works closely with compounding pharmacies that are certified in peptide protocols to help deliver the best possible results to our patients. With the ability to compound peptides into injectables, creams, and capsules; we are able to effectively tailor treatments to meet individual needs.

Our practice has been continuing to expand its peptide therapy offerings over the past few years. We have experience and patient success stories to demonstrate excellent results for overall health.

Benefits of Peptide Therapy

Fat Loss

Increased Lean Muscle Mass

Improved Memory

Improved Collagen

Tissue Repair

Improved Immune System

Improved Wellness

Increase Human Growth Hormone levels

Improve Wound Healing and Recovery

Improved Sleep

Improved Sex Drive and Libido

What are Peptides?

Peptides are small chains of amino acids. They occur naturally in the body and are present in every living cell. When linked together, they initiate many different cellular processes. Specific amino acids stimulate the production of specific hormones and proteins. If your body is no longer making enough of its own peptides, it will no longer be able to function at optimal levels.

Peptides have actually been used in medicine for decades! Insulin is a peptide and has been available for nearly 100 years! Because your body already has receptors for peptides and produced these peptides at higher levels when you were younger or healthier, the use of them should not be considered “foreign” or even “medicinal.” Peptide therapy is merely reviving optimal peptide levels to where they were when we were at our peak!

Why You Shouldn’t Buy Peptides Online

How can you possibly trust your health and life to a vial of powder or liquid purchased from non-approved sources without regard to evidence of purity or potency, much less sterility! Just one injection from a contaminated product could result in sepsis, meningitis, or worse, death!

While online peptides are “cheap”, you get what you pay for. These internet peptides are not regulated, so you have no way to know if you are even receiving a peptide. If it is a peptide, there is a high likelihood that the bonds are cheaply produced and as a result, deteriorate rapidly. A peptide/protein’s function is 100% determined by its structure and internet peptides tend to fall apart within days if not minutes, making them completely inactive very quickly, and therefore a poor investment.

A patient who took a chance and bought cheap, internet peptides and then decided he was risking his life on a dubious product at best, described his experience beautifully. He said he was ordering some new “Air Jordans” when he got a pop up for “cheaper” Air Jordans on a competing website. He bought the cheaper pair. Three weeks later, a shoddy box arrived. In it were a pair of poorly imitated, poorly constructed, shoes. He said, ‘“Dr. Ibrahim, I could tell that these were not anywhere near the quality of real Air Jordans. But there is no way in the world to know anything of the powder in those vials of cheap peptides that I had been buying and without results. So I want to get back on the “real” version of peptides before I kill myself on these fake ones!”

Peptide Programs

At Biltmore Restorative Medicine, our peptides are uniquely created for each patient’s specific goals and needs. Below you will find information about our most popular peptides.

Age Combating Peptides

At Biltmore Restorative Medicine, our peptides are uniquely created for each patient’s specific goals and needs. Below you will find information about our most popular peptides.

Growth Hormone Enhancement

Growth Hormone levels peak in our mid-twenties and then begin a sure and steady decline. If discovered today, it would be called something like “human regenerative hormone” for its amazing ability to repair and regenerate tissues. Increased levels of Growth Hormone has been thought to be one of the most effective methods to combat the effects of aging. Growth Hormone also plays an important role in “lipolysis”, the breakdown and elimination of fat within the body.

Sermorelin, CJC 1295/Ipamorelin, and Tesamorelin

These peptides stimulate your body to produce more optimal levels of growth hormone, so your body stays in charge! Its safety is beyond reproach as the feedback loop remains intact.

Human Growth Hormone itself is hugely expensive and highly controlled whereas the above peptides are neither. Another reason why we prefer to use these peptides to induce your own body to produce what it did when you were healthier and younger.

CJC 1295/Ipamorelin, Sermorelin, and Tesamorelin

These peptides increase muscle mass which then leads to burning more calories or fat, especially visceral or deep belly fat, which is so stubborn to address for most of us. They also all play a role in boosting our intrinsic Growth Hormone levels which will repair many of the problems that occur with aging.

CJC 1295/Ipamorelin

CJC1295 combined with Ipamorelin provides a synergistic effect, generating five times the benefits of using either alone. This compounded blend allows for the maximized release of GH because the CJC 1295 and Ipamorelin have different mechanisms of action and work on different receptors (GHRH-R & Ghrelin-R). Together, they generate similar increases in growth hormone secretion, but without the appetite stimulation and increase in cortisol, acetylcholine, prolactin, and aldosterone seen with other related peptides. Increased muscle mass and fat loss can be expected by regular use of these peptides

Ipamorelin

Ipamorelin stimulates the release of growth hormones mimicking your body’s natural process, which distinguishes it from other GH peptides used for weight loss. Ipamorelin produces the following health benefits:

CJC 1295/ Ipamorelin aren’t anabolic steroids or synthetic hormones that gym “rats and bodybuilders” abuse. They are peptides that your own body produces.

Sermorelin

Sermorelin is a bioidentical hormone that mimics Human Growth Hormone. It is a “secretagogue.” It stimulates the natural secretion of HGH. The result is increased and optimal levels of HGH. Because the body’s feedback loop remains intact, no overdosing or resistance is possible.

Tesamorelin

Tesamorelin is the latest growth hormone-releasing hormone analog. It performs like endogenous GHRH. Tesamorelin has been shown to decrease deep belly or visceral fat. Further, it has been shown to improve cognitive function and mild cognitive impairment and may play a role in preventing or delaying Alzheimer’s disease.

GHK-Cu

GHK-Cu is known as a “copper” peptide and promotes wound healing, produces anti-oxidant and anti-inflammatory effects, stimulates collagen production, and promotes new blood vessel formation.

Cerebrolysin

Cerebrolysin has been shown to repair neurological tissues. Because this peptide can cross the blood-brain barrier, it is possible to reach damaged neurons within the brain and spinal cord! A very powerful tool! This peptide is being used to treat traumatic brain injury, strokes, dementia, and Alzheimer’s disease.

Peptides and Weight or Fat Loss

Why is losing weight or fat so hard to do?

Basically, it should be simple: expend more calories than consumed. Easy, right!

Well, as we all know, it’s not so simple. Without enough muscle to burn calories 24 hours a day, you just can’t “exercise” enough to lose this weight. And without optimal peptide levels, the “system” that burns calories (fat) fails to function properly.

The following are peptides that have been shown to be remarkably effective in helping folks to shed excess fat and lose weight.

Growth Hormone Enhancement

Growth Hormone levels peak in our mid-twenties and then begin a sure and steady decline. If discovered today, it would be called something like “human regenerative hormone” for its amazing ability to repair and regenerate tissues. Increased levels of Growth Hormone has been thought to be one of the most effective methods to combat the effects of aging. Growth Hormone also plays an important role in “lipolysis”, the breakdown and elimination of fat within the body.

Sermorelin, CJC 1295/Ipamorelin, and Tesamorelin

These peptides stimulate your body to produce more optimal levels of growth hormone, so your body stays in charge! Its safety is beyond reproach as the feedback loop remains intact.

Human Growth Hormone itself is hugely expensive and highly controlled whereas the above peptides are neither. Another reason why we prefer to use these peptides to induce your own body to produce what it did when you were healthier and younger.

CJC 1295/Ipamorelin, Sermorelin, and Tesamorelin

These peptides increase muscle mass which then leads to burning more calories or fat, especially visceral or deep belly fat, which is so stubborn to address for most of us. They also all play a role in boosting our intrinsic Growth Hormone levels which will repair many of the problems that occur with aging.

CJC 1295/Ipamorelin

CJC1295 combined with Ipamorelin provides a synergistic effect, generating five times the benefits of using either alone. This compounded blend allows for the maximized release of GH because the CJC 1295 and Ipamorelin have different mechanisms of action and work on different receptors (GHRH-R & Ghrelin-R). Together, they generate similar increases in growth hormone secretion, but without the appetite stimulation and increase in cortisol, acetylcholine, prolactin, and aldosterone seen with other related peptides. Increased muscle mass and fat loss can be expected by regular use of these peptides

Ipamorelin

Ipamorelin stimulates the release of growth hormones mimicking your body’s natural process, which distinguishes it from other GH peptides used for weight loss. Ipamorelin produces the following health benefits:

CJC 1295/ Ipamorelin aren’t anabolic steroids or synthetic hormones that gym “rats and bodybuilders” abuse. They are peptides that your own body produces.

Sermorelin

Sermorelin is a bioidentical hormone that mimics Human Growth Hormone. It is a “secretagogue.” It stimulates the natural secretion of HGH. The result is increased and optimal levels of HGH. Because the body’s feedback loop remains intact, no overdosing or resistance is possible.

Tesamorelin

Tesamorelin is the latest growth hormone-releasing hormone analog. It performs like endogenous GHRH. Tesamorelin has been shown to decrease deep belly or visceral fat. Further, it has been shown to improve cognitive function and mild cognitive impairment and may play a role in preventing or delaying Alzheimer’s disease.

AOD 9604

AOD 9604 works by mimicking the way natural Growth Hormone regulates fat metabolism but without the negative effects on blood sugar or growth. AOD 9604 stimulates fat reduction or lipolysis. This is one of the most powerful visceral fat reduction peptides in our arsenal.

Like Growth Hormone, AOD 9604 stimulates lipolysis (the breakdown or destruction of fat) and inhibits lipogenesis (the transformation of nonfat food materials into body fat) both in laboratory testing and in animals and humans. Recent findings have shown, in addition to its fat loss properties, AOD 9604 processes many other regenerative properties associated with growth hormone. Currently, trials are underway to demonstrate the application of AOD 9604 in osteoarthritis, hypercholesterolemia, bone and cartilage repair. AOD 9604 has an excellent safety profile, recently obtaining Human GRAS status in the USA.

Reduces body fat.

Regulates fat metabolism.

Stimulates Lipolysis.

Inhibits Lipogenesis.

Triggers fat release.

IGF-1

IGF-1 mediates the effects of growth hormone (GH). This peptide is often used in combination with AOD 9604 as its primary effect is fat burning with a secondary benefit of increased muscle mass

Gut Peptides:
IBS, Leaky Gut, and Related Gut Issues

BPC-157

BCP-157 is stable in human gastric juice and can cause a healing effect in both the upper and lower GI tract, improves ulcers, and addresses inflammatory bowel disease (IBD). This peptide is often used to help those with diarrhea, constipation, pain, and gut inflammation.

BCP-157 is also known to promote wound healing and many other regenerative functions.Unlike most peptides, BCP-157 is also available in both oral (pill) and injectable forms.

Peptide Therapy for Sexual Function in Women and Men

What was once a taboo subject has now been brought out to the forefront online andin social media outlets. Pop up advertisements are everywhere for sexual enhancement once, only directed toward men but now, women are asking, “Where’s mine?”

Some of the patients that get the most benefit from our practice are those seeking more fulfilling sexual health. Between treatments to optimize sex hormone levels, procedures to stimulate new blood vessels and nerve tissue to the external genitalia directed physical therapies, and peptides that stimulate neurochemicals; we have seen tremendous improvement in an area that most people don’t realize can actually get better.

By stimulating the dopamine secretion in a person, sexual desire can be directly increased. The areas of the brain in which we stimulate sexual motivation, also benefit energy, and even help skin become tanner! This peptide is considered a “neuro aphrodisiac” and all of the effects that we see with this injection benefit men and women indiscriminately.

Peptide science has gotten farther than most people realize. We can amplify, modify, and create greater efficiency in intracellular signaling and function. When treatments include the right combinations of peptides, patients can benefit. This is truly Restorative Medicine.

Bremelanotide PT141

Originally developed from Melanotan II (the tanning peptide), PT-141 targets its aphrodisiac effects. What differentiates peptides such as PT-141 from other sexual medications is that it directly targets the area of the brain that controls libido, erectile function, and general sexual response.

Unlike Viagra and its cousins used for erectile dysfunction (ED) for men, PT-141 improves sexual dysfunction in both men and women. This peptide substantially enhances libido, generating sexual arousal in both men and women within minutes of administration.

PT-141, which does not affect the vascular system, works directly on a woman’s mind to promote sexual desire. It has also been shown to be effective in treating erectile dysfunction, even in men who have failed other ED treatments, such as Viagra and Cialis. This peptide crosses the blood-brain-barrier, bypassing the vascular system, and acts upon the central nervous system.

PT 141 is also an FDA approved drug when prescribed by a licensed medical provider.

Loss of sexual desire is not only a real problem, but it’s also a real “disease”, known in medical terms as hypoactive sexual desire disorder (HSDD) and is the most common form of female sexual dysfunction at any age.

The effects can last for hours and even be noticeable for several days!

Effects of PT 141

Women and PT-141

Less than half of the women in the United States experience what they describe as “little or no satisfaction” from intercourse and only 25% achieve orgasm with intercourse. Fortunately, we now have treatments for women who wish to experience greater sexual fulfillment, intimacy, and enhanced relationships. More women reported moderate or high sexual desire following PT-141 treatment vs. placebo. Among women who used PT-141, significantly more were satisfied with their level of sexual arousal, compared with placebo.

Men and PT-141

Men report improved erectile quality (firmness), quicker erections, longer-lasting erections, more frequent erections, and more intense orgasms. Unlike Viagra and the likes, there is no facial flushing, nasal congestion, and indigestion.

Peptides for Strength & Lean Muscle Mass​

Growth Hormone Enhancement

Growth Hormone levels peak in our mid-twenties and then begins a sure and steady decline. If discovered today, it would be called something like “human regenerative hormone” for its amazing ability to repair and regenerate tissues. Growth Hormone also plays an important role in “lipolysis”, the breakdown and elimination of fat within the body.

Sermorelin, CJC 1295/Ipamorelin, and Tesamorelin

These peptides stimulate your body to produce more optimal levels of growth hormone, so your body stays in charge! Its safety is beyond reproach as the feedback loop remains intact.

Human Growth Hormone itself is hugely expensive and highly controlled whereas the above peptides are neither. Another reason why we prefer to use these peptides to induce your own body to produce what it did when you were healthier and younger.

CJC 1295/Ipamorelin, Sermorelin, and Tesamorelin

These peptides increase muscle mass which then leads to burning more calories or fat, especially visceral or deep belly fat, which is so stubborn to address for most of us.

CJC 1295/Ipamorelin

CJC1295 combined with Ipamorelin provides a synergistic effect, generating five times the benefits of using either alone. This compounded blend allows for the maximized release of GH because the CJC 1295 and Ipamorelin have different mechanisms of action and work on different receptors (GHRH-R & Ghrelin-R). Together, they generate similar increases in growth hormone secretion, but without the appetite stimulation and increase in cortisol, acetylcholine, prolactin, and aldosterone seen with other related peptides. Increased muscle mass and fat loss can be expected by regular use of these peptides.

Ipamorelin

Ipamorelin stimulates the release of growth hormones mimicking your body’s natural process, which distinguishes it from other GH peptides used for weight loss. Ipamorelin produces the following health benefits:

CJC 1295/ Ipamorelin aren’t anabolic steroids or synthetic hormones that gym “rats and bodybuilders” abuse. They are peptides that your own body produces.

Sermorelin

Sermorelin is an FDA approved bioidentical hormone that mimics Human Growth Hormone. It is a “secretagogue.” It stimulates the natural secretion of HGH. The result is increased and optimal levels of HGH. Because the body’s feedback loop remains intact, no overdosing or resistance is possible.

Tesamorelin

Tesamorelin is the latest growth hormone-releasing hormone analog. It performs like endogenous GHRH. Tesamorelin has been shown to decrease deep belly or visceral fat. Further, it has been shown to improve cognitive function and mild cognitive impairment and may play a role in preventing or delaying Alzheimer’s disease.

Joint and Muscle Peptides

There are several peptides that may help you repair joint and muscle injuries, wear and tear, and other painful skeletal-muscular problems.

BPC-157

BPC-157, also known as the Body Protection Compound, may be taken by mouth (orally) or as an injectable. The peptide has been shown to dramatically aid in the repair of muscle, tendons, ligaments, bone, gut, skin, eyes, and the brain.

Thymosin Beta 4 (TB4)

TB4 is a hormone produced by the thymus gland. It boosts T cell production which strengthens the immune system. This hormone also plays a major role in the repair of bodily tissues.

AOD 9604

Also discussed for fat metabolism, AOD 9604 has been shown to speed up the recovery of muscle and joint injuries. Currently, trials are underway to demonstrate the application of AOD 9604 in osteoarthritis, hypercholesterolemia, bone, and cartilage repair. AOD 9604 has an excellent safety profile, recently obtaining Human GRAS status in the USA.

Hair and Skin Peptides

Zinc Thymulin (ZT)

Zinc Thymuin (ZT) has been used to restore hair loss due to androgenic alopecia which occurs in both men and women. The most common form of hair loss in men is androgenic alopecia so this has become a very valuable tool. Zinc deficiency has also been linked to hair loss. This combination is often used in a topical spray form.

Melanotan-2 (M2)

Want a natural tan without the damaging effects caused by UV exposure? Melanotan-2 is the peptide used to induce the skin’s melanocytes to produce natural melanin, resulting in a natural tan, which protects the deeper layers from the damaging effects of the sun. An added benefit is increased libido, improved erections, and a reduction in body fat!

Immune Boosting Peptides

Thymosin alpha 1 (TA1)

Thymosin alpha 1 is produced in the thymus and promotes T cell production which strengthens the immune system. This peptide may help both active infections as well as patients with auto-immune diseases.

Thymosin Alpha-1 is a protein that consists of 28 amino acids. Thymosin Alpha-1 is believed to be a significant component of Thymosin Fraction 5 responsible for the activity of that preparation in repairing immune function. It has been found to improve cell-mediated immunity in humans. Thymosin Alpha-1 plays a vital role in the control of immunity, tolerance, and inflammation. It manages immune response via an initial action on the cells of the innate immune system and thus acts as an endogenous regulator of both inflammatory and adaptive immune responses. Thymosin alpha-1’s immunomodulatory activities are centered primarily on the augmentation of T-cell function.

Peptide Therapy for Aesthetics

Our Face Cream!DMAE / ESTRIOL / GHK-CU / HYALURONIC ACID BIOPEPTIDE

GHK-Cu is a naturally occurring copper complex that was first identified in human plasma. Copper peptides are small, naturally occurring protein fragments that have a high affinity for copper ions, which are critical to normal body function.

Since its discovery in 1973, GHK-Cu established itself as a powerful protective and regenerative ingredient, which is currently widely used in skin and hair products.

It stimulates blood vessel and nerve outgrowth, increases collagen, elastin, and glycosaminoglycan synthesis, as well as supports the function of dermal fibroblasts. It then plays a significant role in signaling tissue remodeling which removes damaged/scarred tissue and generates new, healthy tissue. However, these positive effects decline with age because the concentration of GHK-Cu in the body decreases with age.

This is an elegant cream designed for cosmetic facial use.

Tighten loose skin and reverse thinning of aged skin.

Repair protective skin barrier proteins.

Improve skin firmness, elasticity, and clarity.

Reduce fine lines, depth of wrinkles, and improve the structure of aged skin

The role of dimethylaminoethanol in cosmetic dermatology.

Mitigation forehead lines and periorbital fine wrinkles, and in improving lip shape and fullness and the overall appearance of aging skin.

These effects did not regress during a 2-week cessation of application. Beneficial trends (p > 0.05 but </= 0.1) were noted in the appearance of coarse wrinkles, under-eye dark circles, nasolabial folds, sagging neck skin, and neck firmness. The application was found to be well tolerated, with no differences in the incidence of erythema, peeling, dryness, itching, burning, or stinging between the DMAE and placebo groups.

Hyaluronic acid: A key molecule in skin aging

The key molecule involved in skin moisture is hyaluronic acid (HA) that has a unique capacity in retaining water. There are multiple sites for the control of HA synthesis, deposition, cell and protein association, and degradation, reflecting the complexity of HA metabolism. The enzymes that synthesize or catabolize HA and HA receptors responsible for many of the functions of HA are all multigene families with distinct patterns of tissue expression. Understanding the metabolism of HA in the different layers of the skin and the interactions of HA with other skin components will facilitate the ability to modulate skin moisture in a rational manner.

Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data

Up-to-date, it is established that GHK-Cu is able to:

Tighten loose skin and reverse thinning of aged skin.

Repair protective skin barrier proteins.

Improve skin firmness, elasticity, and clarity.

Reduce fine lines, depth of wrinkles, and improve the structure of aged skin.

Treatment of skin aging with topical estrogens.

After treatment for 6 months, elasticity and firmness of the skin had markedly improved and the wrinkle depth and pore sizes had decreased by 61 to 100% in both groups. Furthermore, skin moisture had increased and the measurement of wrinkles using skin profilometry revealed significant, or even highly significant, decreases of wrinkle depth in the estradiol and the estriol groups, respectively.

GHK-Cu creams/injections

One of the most promising areas in aesthetics is peptide therapy. A key player is the proper use of GHK-Cu. The systemic ramifications of this peptide trifecta are mind and mirror blowing.

To say GHK-Cu is a great addition to your aesthetics regime is a severe understatement. An itemized breakdown of how this tri-peptide can improve the human body reads like a wish list.

First developed in the early 1970’s science has continued to harness the copper-binding ability this peptide has to manage many human conditions. Proven benefits affect hair and skin comprehensively:

Tightening and reversing aged, thin skin

Improving skin elasticity and clarity

Reduction of fine lines and improvement of skin structure

Repair of photo-damage, skin spots, and wounds

Protection from UV radiation and improvement of skin barrier proteins

Increasing hair follicle thickness.

Decreasing the damage done by free radicals

Reduction of systemic inflammation

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Why Choose Dr. Ibrahim?

Dr. George Ibrahim is the go-to doctor for the most effective non-invasive, aesthetic procedures on the planet.

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A message from Dr. Ibrahim

With COVID-19 circulating across the US, Biltmore Restorative Medicine, as a medical facility, is committed to ultimate cleanliness and sanitation. We have taken every measure to ensure we remain sanitary and we take every precaution for the health and safety of our patients.

We remain open and fully operational during this time with adjusted hours:
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