MOSCOW (Reuters) - A Russian military jet crashed while taking off from Russia’s Hmeymim air base in Syria on Tuesday in an incident that killed its two-man crew, Russia’s Defense Ministry said, Russian news agencies reported.

A still image taken from a file video footage shows a Russian Sukhoi Su-24 military jet taxiing on the tarmac at the Hmeymim air base near Latakia, Syria. Ministry of Defence of the Russian Federation/Handout via REUTERS

The Sukhoi-24 attack aircraft, codenamed Fencer by the NATO military alliance, was heading out on a combat mission, but its crew failed to eject after the plane veered off the runway, the ministry was cited as saying.

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A technical fault may have been to blame, the ministry said.

Russia has used the Hmeymim base in Latakia Province to launch air strikes against opponents of President Bashar al-Assad since it first intervened in the Syrian conflict in September 2015.

Russia lost two other planes - a Sukhoi-33 and a MiG-29 - off the coast of Syria last year in accidents involving its sole aircraft carrier, the Admiral Kuznetsov.