ProHance

SIDE EFFECTS

The adverse events described in this section were observed
in clinical trials involving 1251 patients (670 males and 581 females). Adult
patients ranged in age from 18-91 yrs. Pediatric patients ranged from 2-17
years. The racial breakdown was 83% Caucasian, 8% Black, 3% Hispanic, 2% Asian,
and 1% other. In 2% of the patients, race was not reported.

The most commonly noted adverse experiences were nausea and
taste perversion with an incidence of 1.4%. These events were mild to moderate
in severity.

The following additional adverse events occurred in fewer
than 1% of the patients: