Silverman also called the Bernie or Bust folks "nutso." However, as a Sanders supporter during the primary, she said she believes most Bernie folks are "reasonable."

"I think most Sanders supporters are reasonable people who think, you know, Bernie and Hillary have so much in common. They have a lot of the same values," she said.

Silverman was among a line-up of major names who spoke at the convention Monday night. In addition to the comedian, rising Democratic star Senator Cory Booker, Senator Elizabeth Warren and Senator Bernie Sanders all gave their arguments to elect Hillary.