Target Details FDFT1

FDFT1 is a membrane-associated enzyme located at a branch point in the mevalonate pathway. The protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.Alias Symbols: DGPT, ERG9, SQS, SSProtein Interaction Partner: UBC, MDM2, FBXO6, EGFR, GLP1R, HDAC10, UBL4A, FN1, UBD, RUVBL2, TMEM43, FAM101A, SHPRH, ARL6IP1, ANXA5, SMNDC1, PSTPIP1, RUVBL1,Protein Size: 417