Since the FDA asks the manufactures to do their own research, "on the honor system", don't expect either to look out for your interests. No Tooth Fairy or Santa Claus here - but their not real anyway - but FDA approval is real, of course it means nothing, except to naive, fools. And how many lawyers do have on staff and retainer; and how many heathcre professionals (you will need them for long term care)? Don't worry they won't kill you the same day, or year that would be murder by poisoning, you might get the D.A. to help you with that 'justice'.The Neurotoxic Properties of Splenda the popular artificial sweetener is sucralose, sold under the brand name Splenda. Sucralose is a synthetic chemical created in a five-step patented process, in which three chlorine molecules are added to one sucrose (sugar) molecule. Some will argue that natural foods also contain chloride, which is true. However, in natural foods, the chloride is connected with ionic bonds that easily dissociate when ingested. In Splenda, they're in a covalent bond that does not dissociate. And, since your body has no enzymes to break down this covalently bound chloride, harm can ensue... The reason why your body has no enzymes for this task is because, in nature, there are NO covalent chloride bonds to organic compounds—they only exist in synthetic, man-made form. Aside from Splenda, other examples of synthetic covalently bound chloride compounds include DDT, PCBs, and Agent Orange. Previous research indicates that about 15 percent of sucralose is absorbed into your digestive system, and ultimately stored in your body fat. A 2008 animal study1 found that Splenda reduced the amount of beneficial intestinal bacteria by 50 percent, increased the intestinal pH level, and affected a glycoprotein that can have crucial health effects, particularly if you're on certain medications. More recent research2 detailing Splenda's oxidative effects, suggests the sweetener may have neurotoxic properties, which doesn't surprise me in the least. The researchers, who assessed the effects of sucralose on water fleas, concluded that: "exposure to sucralose may induce neurological and oxidative mechanisms with potentially important consequences for animal behavior and physiology." As reported by www.GreenMedInfo.com

"Like so many novel patented chemicals released onto the market without adequate pre-approval safety studies, we do not know if this preliminary toxicological research will be applicable to human exposures. In fact, there are only 318 study citations on this chemical in existence since it first began to be researched in the 70's. This most recent study is the first in existence to look at its effect on the enzyme acetylcholinesterase, which is found in all animals.

This information deficit is all the more remarkable when you consider there are over 7,000 published studies in existence on either natural herb turmeric or its primary polyphenol curcumin, which is still not readily administered by the conventional medical establishment mostly due to '﻿safety concerns﻿,' despite what the voluminous positive data on its relevance to over 600 health conditions indicates."