From 1982 to 1984, he was a member of the band Chequered Past, which also included two of his former bandmates: Des Barres, from Silverhead, and Clem Burke, from Blondie. They released an eponymous album in 1984. Harrison was also music supervisor/producer for the soundtrack to the 1988 comedy Tapeheads.

When Blondie started to talk about re-forming in 1997, Harrison was initially asked to rejoin the group. He recorded demo tracks with the band for the album No Exit (1999), but was dropped from the band before the record was finished. He and another excluded former member, Frank Infante, brought a lawsuit over the dispute, but were unsuccessful.[2]

Harrison was an A&R Executive at Interscope Records who also did A&R work for Capitol Records. [3]

He is now the bass player for The Grabs, whose album Sex, Fashion And Money was released in November 2005.

In March 2006, Blondie, following an introductory speech by Shirley Manson of Garbage,[4][5] were inducted into the Rock and Roll Hall of Fame.[6] Seven members were invited to the ceremony, which led to an on-stage spat between the extant group and their former bandmates, Nigel Harrison and Frank Infante, who asked during the live broadcast of the ceremony to be allowed to perform with the group, a request refused by Debbie Harry.[7]