Eminent scientists have contributed comprehensive reviews on all aspects of the genomics of Rhodococcus, Mycobacteria, Streptomyces and other organisms. The authors provide an insight into the many facets of large-scale functional investigation in a variety of bacteria with the explicit goal to find common rules in the dynamic and structural organisation of these organisms. This volume is the definitive guide to current research in this increasingly important area.

Reviews

"This book focuses on the impact that complete genome sequence information has and will have on our knowledge of these bacteria ... this book is a welcome addition."fromMicrobiology Today (2003) 30: 192-196.

"This volume brings together ... work done in the area of the genomics of Rhodococcus, Mycobacterium tuberculosis, M. leprae, and Streptomyces.... timely reviews on many facets of the genetics of the above-mentioned organisms."fromInternational Journal of Medical Microbiology (2003) 293 (1).

"The Functional Genomics Series describes the state-of-the-art of technical means to efficiently analyse sequence information - provided by the nascent disciplines of bioinformatics and computational biology - and the need to fit the genomic pieces into the puzzle of biological function, resulting in an understanding of the functioning of complex systems of genes and macromolecules."fromInternational Microbiology (2003) 6: 75-78.

"Reading this volume is very rewarding for microbiologists"fromInternational Microbiology (2003) 6: 75-78.

Table of contents

1. Genomes and Evolution

Antoine Danchin

2. Genetic Organization of Rhodococcus

Leonid A. Kulakov and Michael J. Larkin

3. Functional Genomics for the Discovery of New Mycobacterium tuberculosis Virulence Factors

Olivier Neyrolles and Brigitte Gicquel

4. Global Analysis of Streptomyces

Jean-Luc Pernodet and Philippe Mazodier

5. Impact of the Mycobacterium leprae Genome Sequence on Leprosy Research