Protein expression - VIM

Normal kidney showing the expression of vimentin (VIM) in mesenchymal cells, including blood vessels throughout the kidney.

Vimentin (VIM) - Marker for mesenchymal cells

Vimentin is an intermediate filament protein ubiquitously expressed mesenchymal cells, and is therefore used clinically to identify mesenchyme and sarcoma tumors. The function of vimentin is to provide cellular integrity and cell shape by supporting and anchoring organelles within the cytoplasm.