For the Consumer

Along with its needed effects, senna (the active ingredient contained in Senna-gen) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking senna:

For Healthcare Professionals

Gastrointestinal

Gastrointestinal side effects have included esophageal impaction and duodenal bezoars. These effects have been reported in patients receiving a bulk laxative product containing 82% psyllium and 18% senna (the active ingredient contained in Senna-gen) (commercially available as Perdiem Overnight Relief).[Ref]

Hypersensitivity

Hypersensitivity side effects have rarely included occupational sensitization to senna (the active ingredient contained in Senna-gen) [Ref]

One case has been reported involving a factory worker who developed IgE-mediated asthma and rhinoconjunctivitis five months after exposure to senna.[Ref]

Musculoskeletal

Musculoskeletal side effects have rarely included finger clubbing.[Ref]