Sex-based young adult asthma risks associated with acetaminophen use

Previous studies have identified an association between acetaminophen use and asthma risk.

This article is part of The Clinical Advisor’s conference coverage from the American Academy of Allergy, Asthma & Immunology in Orlando, Florida. Our staff will report on medical research related to asthma and other respiratory conditions, conducted by experts in the field. Check back regularly for more news from AAAAI/WAO 2018.

In a recent study, researchers found that male patients who had used acetaminophen at least once in the past month had a higher asthma risk than males who reported no acetaminophen use in the past year, but that did not hold true for female patients.

The researchers conducted statistical analysis on allergy datasets from the Isle of Wight in the United Kingdom (IOW; n=1456; age 18 years) and the Kuwait University allergy study (KUAS; n=1154; age 18-26 years) that included self-report of acetaminophen use, asthma diagnosis, and symptoms in young adults. The analysis involved Poisson regression with robust variance estimation to infer prevalence ratio, and the team then examined the data stratified by sex.

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