5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides (225 aa)

0.955

CC1G_14657

4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate (364 aa)

0.912

CC1G_11046

atypical/ABC1/ABC1-A protein kinase (741 aa)

0.886

COQ4

Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family (291 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

CC1G_00949

CC1G_04199

XP_001831402.2

XP_001833220.2

COQ6 monooxygenase

Mitochondrial protein

0.692

CC1G_00949

CC1G_10317

XP_001831402.2

XP_001837896.2

COQ6 monooxygenase

FMN adenylyltransferase

0.692

CC1G_00949

CC1G_11046

XP_001831402.2

XP_001834076.2

COQ6 monooxygenase

atypical/ABC1/ABC1-A protein kinase

0.886

CC1G_00949

CC1G_11850

XP_001831402.2

XP_001841322.2

COQ6 monooxygenase

Oxidoreductase

0.688

CC1G_00949

CC1G_14173

XP_001831402.2

XP_002911640.1

COQ6 monooxygenase

atypical/ABC1/ABC1-B protein kinase

0.752

CC1G_00949

CC1G_14657

XP_001831402.2

XP_002911228.1

COQ6 monooxygenase

4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate

Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family

5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides

0.955

CC1G_04199

CC1G_00949

XP_001833220.2

XP_001831402.2

Mitochondrial protein

COQ6 monooxygenase

0.692

CC1G_04199

CC1G_14657

XP_001833220.2

XP_002911228.1

Mitochondrial protein

4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate

Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family

5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides

0.656

CC1G_10317

CC1G_00949

XP_001837896.2

XP_001831402.2

FMN adenylyltransferase

COQ6 monooxygenase

0.692

CC1G_11046

CC1G_00949

XP_001834076.2

XP_001831402.2

atypical/ABC1/ABC1-A protein kinase

COQ6 monooxygenase

0.886

CC1G_11046

CC1G_11850

XP_001834076.2

XP_001841322.2

atypical/ABC1/ABC1-A protein kinase

Oxidoreductase

0.637

CC1G_11046

CC1G_14173

XP_001834076.2

XP_002911640.1

atypical/ABC1/ABC1-A protein kinase

atypical/ABC1/ABC1-B protein kinase

0.683

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: