Lyle, when you wrote that the consumption of protein more frequently than every 3 hours may/is potentially detrimental for mass gains from a MPS standpoint, is that time frame from the beginning of a meal or the end? I have experimented with IF and my meals can last close to an hour.

It should theoretically be from the beginning of a meal to the beginning of the next meal, as that is when the blood AA levels begin to rise, but realistically larger meals of longer durations would keep AA levels elevated for longer and you would have to space them out more to compensate. IF may be an exception as you have an extended fasting period which increases sensitivity to protein feedings, so as long as you get in your 3 meals within the 8hr feeding window you should be fine.

I would say eating a meal 1 hour after your workout and having your post workout shake (which may be 50g's of protein and let's say 75g's of carbs)...would mostly come from...after I have my protein-carb shake after I workout...I can't eat at all I'd probably feel sick...but an hour later I am a VERY hungry person. I always eat an hour after a workout...I drink that shake, my stomach settles..and then I'm starving lol

when is protein synthesis the highest in advanced trainees? Ive read that protein synthesis is only elevated for like 16 hours in people who have closed in on their genetic potential.

After training I have zero appetite but I eat a big meal anyways. Im thinking of eating something small and/or a protein-shake and eat a bigger meal a couple hours later because Im hungrier then. I do IF btw.

I think there was JUST a thread that touched on this but I can't remember what the original topic was to search for it.

Most studies find that PS peaks 24-36 hours PWO but they aren't using advanced trainees in those studies. I believe it was said to be reduced in advanced trainees but I can't remember if anything was said beyond speculation. I guess this is of no real help other than there is a thread out there if you can find it. I think Blade and mrlakramondas posted in the thread if that helps.