Overview

MeSH Major

Frontal Lobe

Image Processing, Computer-Assisted

Limbic System

Magnetic Resonance Imaging

Oxygen

Premenstrual Syndrome

abstract

The results support a neurobiological model of enhanced negative emotional processing, diminished positive emotional processing, and diminished top-down control of limbic activity in PMDD during the premenstrual phase. These findings provide a basis for a neurocircuitry model of PMDD, and have implications for studies of mood/emotional regulation across the human menstrual cycle in health and disease.