It depends. The answer to this really depends on the stage, grade and histology of the endometrial cancer. For example, early stage, low grade adenocarcinomas have a low chance to metastasize whereas a higher stage, papillary serous type endometrial cancer has a higher risk of metastasizing.

Endometrial cancer. It depends on the type of endometrial cancer, the grade of endometrial cancer and the thoroughness of the initial surgery. While the most common type spreads only about 15% of the time other more aggressive types spread more often (40-50%).