Phoenix, USA to Manuel Antonio is an approximately 17.5-hour flight. Traveling from Phoenix to Manuel Antonio, you'll lose 1 hour due to the time zone difference. When traveling from Phoenix in April, plan for little chillier days and about the same nights in Manuel Antonio: temperatures range from 82°F by day to 67°F at night. Cap off your sightseeing on the 18th (Wed) early enough to go by car to Uvita.

You can drive from Manuel Antonio to Uvita in 1.5 hours. Another option is to take a bus. Wrap up your sightseeing by early afternoon on the 19th (Thu) to allow enough time to travel to La Fortuna de San Carlos.

You can do a combination of bus and flight from Uvita to La Fortuna de San Carlos in 3.5 hours. Alternatively, you can drive; or do a combination of bus and car. Wrap up your sightseeing by early afternoon on the 22nd (Sun) to allow enough time to travel back home.