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THE Wallabies' incredible run of injury has continued with centre Pat McCabe ruled out of Sunday's Test against England with a neck injury.

Having suffered a muscle strain against France, McCabe was unable to shake off the discomfort and was yesterday declared a non-starter for the Twickenham clash.

It is expected either Ben Tapuai or Mike Harris will move to No. 12, with Berrick Barnes to remain at fullback.

Harris has played No. 12 for the Reds but Tapuai's move from outside centre to inside centre would free up Adam Ashley-Cooper to move to his preferred No. 13 role, and Digby Ioane and Nick Cummins on the wings.

McCabe becomes the third player to be ruled out for the England game, following injuries to David Pocock and Kane Douglas.

As far as the whole season goes, McCabe loss would be the latest in several dozen.

"Its been a remarkable year that's for sure," Deans said.

"At this stage it's a one weeker (for McCabe). He jammed his neck up in training and there was some history. He is obviously in discomfort it is a matter of when it will settle."

Deans said the midfield changes - which will be revealed later tonight when the team is named - would need to fit in with the existing gameplan.

"We don't have time to adjust our game to any great extent, so the personnel will have to fit into the game, but they've been part of the prep," he said