Researchers at the Cleveland Clinic Lerner Research Institute developed a way to reverse the development of BACE1, an amyloid plaque that builds up abnormally on the brains of Alzheimer’s disease patients, according to the study that was published in the Journal of Experimental Medicine.

Researchers bred special groups of mice that developed the cognitive atrophying plaque at 75 days old. Then they administered special drugs targeting BACE1, which gradually reduced until there were no signs of the plaque.