Guanine nucleotide-binding regulatory protein (G protein)-coupled receptor kinases
(GRKs) constitute a family of serine/threonine kinases that play a major role in the
agonist-induced phosphorylation and desensitization ...

G protein-coupled receptor activation leads to the membrane recruitment and activation
of G protein-coupled receptor kinases, which phosphorylate receptors and lead to their
inactivation. We have identified a novel ...