Warning: To avoid personal contamination with biohazards and toxic compounds, or the residues of such compounds, wear clean, chemical-resistant, powder-free gloves when performing this procedure.

Caution: To avoid damaging electrical parts, never disconnect an electrical assembly while power is applied to an instrument or device. To completely interrupt power, set the power switch to Off, and then unplug the power cord from the AC source. Wait 10 seconds before you disconnect an assembly.

Remove the fittings attached to the injection valve cartridge.

Use a 2-mm hex wrench to remove the screw at the 10 o’clock position on the injection valve cartridge.

Remove the injection valve cartridge from the injection valve assembly.

Carefully unpack the replacement injection valve cartridge.

Ensure that the groove in the cartridge housing and the groove on the drive clamp align. If they do not align, turn the drive clamp until the grooves line up.

Insert the new injection valve cartridge into the injection valve assembly.

Note: If the injection valve cartridge does not slide fully into the injection valve assembly, contact your Waters service representative.

Insert the 2-mm hex screw at the 10 o’clock position on the injection valve cartridge and tighten it.

Reattach all fittings, ensuring that the tubes sit on the bottoms of their fitting holes.