This third edition of The Pharmacologic Approach to the Critically Ill Patient is truly a magnum opus. It is an exceptionally scholarly work that has at least 75% more content than the second edition. It is a large book with 1220 pages, and it contains virtually everything that anyone would want to know about any pharmacologic problem that might occur in critically ill or injured patients. Virtually all of the chapters have been updated, and, as the editor has pointed out, the third edition provides augmented references in critical care pharmacology and new chapters on drug monitoring, toxicology, muscle relaxants, sedation, immunotherapy, lazaroids, and mucolytic agents. Increased attention has also been focused on the pharmacologic approach to stroke, muscle spasticity, burns, spinal cord injury, and nerve gas poisoning.

There is no question that knowing and remembering the pharmacology involved in the wide variety of drugs now available for use in