NCCAM will accept applications that are responsive to programmatic priority areas for research related to complementary/alternative medicine as detailed in the NCCAM Strategic Plan (www.nccam.nih.gov).

Salary Support: NCCAM will provide salary support commensurate with the applicant institution's salary structure for persons of equivalent qualifications, experience, and rank.

Grants awarded by NCI under this announcement will be funded as Howard Temin Pathway to Independence Awards in Cancer Research.

The candidate's research proposal must be laboratory-based and must include research on the etiology, pathogenesis, prevention, diagnosis, control or treatment of HUMAN cancer. The proposed research may involve model systems, including animal models. However, at some point during the grant period, the proposed research must include work on human cancer (includes human cancer cells or tissues).
Candidates must be able to identify an individual with extensive experience in human cancer research who can serve as a mentor for the initial mentored phase of this award.

NCI encourages those involved in non-laboratory based research to consider applying for the K07 (Cancer Prevention, Control, Behavioral and Population Sciences Career Development Award), the K23 (Mentored Patient-Oriented Research Career Development Award), or the K22 (NCI Transition Career Development Award).

NEI will accept applications for funding that are responsive to programmatic priority areas for research within vision and Ophthalmology as detailed in the National Plan for Eye and Vision Research found at www.nei.nih.gov.

Salary Support: NEI will provide salary support commensurate with the applicant institution's salary structure for persons of equivalent qualifications, experience, and rank.

Prospective applicants are encourage to read A Vision for the Future of Genomics Research (http://www.nhgri.nih.gov/11006873) to familiarize themselves with the research areas of interest to the Institute which include genomics, proteomics, and the ethical, legal and social issues (ELSI) related to genetics and genomics. Program Directors are happy to discuss with potential applicants their concept for this initiative during the development stages of the application.

Salary Support: NHGRI does not impose any salary restriction on the R00 phase of the award beyond that imposed legislatively. The total salary requested must be based on a full-time, 12 month staff appointment for at least 75% effort.

NIAAA sponsors a variety of career development programs to ensure the development of highly qualified investigators in alcohol-related research. Opportunities under the K99/R00 program include research in the social, behavioral, biological and mathematical sciences as related to alcohol abuse and alcoholism.

Postdoctoral fellows currently receiving NIAAA support through the Ruth L. Kirschstein NRSA program (T32 or F32) and postdoctoral fellows in the NIAAA intramural program (DICBR) should also consider the NIAAA Career Transition Award (K22) described at: PAR-06-096.

The K22 and K99/R00 programs are both intended for postdoctoral fellows whose formal research training is nearly complete, and who will soon begin searching for faculty positions. Those whose career development would benefit from further mentored training should also consider the mentored Career Development Awards offered by NIAAA (e.g., K01, K08, K23, K25). Prospective applicants are strongly encouraged to contact Institute program staff to help choose among these career development options.

More information on NIBIB Career Awards can be found at http://www.nibib.nih.gov/Training/CareerLevel. Prospective applicants are strongly encouraged to contact the Program Director listed above to determine if their application is appropriate to NIBIB and to identify the most suitable training mechanism.

The NIDCD welcomes applications from postdoctoral scientists seeking to establish an independent research career in areas of research supported by the Institute: hearing, balance, smell, taste, voice, speech and language. NIDCD will give preference to the award of meritorious K99/R00 applications from: 1) advanced postdoctoral fellows at extramural research institutions who are currently supported by either an NIDCD-sponsored Ruth L. Kirschstein National Research Service Award (NRSA) for Individual Postdoctoral Fellows (F32) or an Institutional NRSA [(Training Grant) (T32)]; and, 2) current Intramural Research Training Awardees (IRTA), visiting fellows or equivalent staff fellows in the NIDCD Division of Intramural Research.

Prior to commencing the third year of the independent investigator (R00) award phase, NIDCD awardees will be expected to have submitted an investigator-initiated research grant (R01) application.

The NIDCR welcomes applications from postdoctoral scientists seeking to establish an independent research career in social, behavioral, biomedical, and biological science fields relevant to the NIDCR Strategic Plan (http://www.nidcr.nih.gov/AboutNIDCR/StrategicPlan/default.htm). Applicants must demonstrate a commitment to a career in oral health research, and funding priority will be given to applicants holding a dental degree.

In addition, although previous K awardees are not generally eligible to apply for a second K award, the NIDCR will accept K99/R00 applications from dentist scientists who have used a previous NIDCR-funded K08 or K23 award to earn the PhD degree. Such applicants must have completed the PhD before applying. All other eligibility requirements and conditions of the K99/R00 mechanism apply.

Transition to the independent investigator phase may be delayed for up to one year in order for the awardee to find a suitable tenure-track (or equivalent) position. In such cases, the NIDCR will not provide interim support.

NIDDK will accept applications from postdoctoral fellows working in the areas of research supported by NIDDK: diabetes, endocrinology, metabolic diseases, obesity, nutrition, digestive and liver diseases, kidney and urological disorders, and hematologic diseases. Program staff will work with applicants to clarify milestones for progression from the K99 to the R00 phase of the award. Applicants should consider applying for the NIDDK K01 award (PAR-05-066) as an alternative to the K99/R00.

Research projects proposed should have a defined focus in the environmental health sciences, and be responsive to the mission of the NIEHS, which is distinguished from that of other Institutes by its support of research programs seeking to understand how environmental exposures alter biologic processes and affect the risk of either disease development or the distribution of disease in populations. Examples of environmental exposures relevant to the mission of the NIEHS include industrial chemicals or manufacturing by-products, metals, pesticides, herbicides, air pollutants and other inhaled toxicants, particulates or fibers, fungal or bacterially derived toxins due to ambient exposures. Agents considered to belong to the mission area of other NIH Institutes include: alcohol, chemotherapeutic agents, ionizing radiation, drugs of abuse, pharmaceuticals, smoking (except second-hand smoke), and infectious or parasitic agents, except when these are disease co-factors with an environmental toxicant exposure to produce the biological effect. Projects focusing on ecology, ecologic or microbial biotransformation, ecologic biodegradation and remediation, ecological monitoring, wildlife and fisheries biology or studies of sentinel species, geochemistry and other ecologically based environmental studies are not considered responsive to this Program Announcement. Research in veterinary medicine where the endpoint is animal health or in food science is also not responsive. Proposals for research in exposure assessment should concentrate on exposure biology, which is at the interface of exposures and human health, and research centered on biomarkers as indicators of body burden, pathophysiological changes, or inception/progression of disease, rather than environmental measurement of ambient contact or point of exposure.

The NIGMS encourages postdoctoral trainees to apply by their third year of postdoctoral training. Awardees must complete at least one full year of mentored training under the K99 phase before transitioning to the R00 phase. Individuals who already have extensive postdoctoral training and expect to transition to an independent position in less than one year may not be appropriate for this grant mechanism. In making funding decisions, the NIGMS will give high priority to applications directly related to the missions of the five Institute divisions and center (http://www.nigms.nih.gov/About/Overview). New K99 awards are generally made from April through September. Before preparing an application, each investigator is encouraged to contact NIGMS staff to discuss the potential application. In some cases, the applicant may discover that there are better options for his/her specific situation. Eligibility: The Pathway to Independence Award is limited to postdoctoral trainees who, at the time of initial application or resubmission, have less than five years of research-related experience since completing requirements for the doctoral degree. NIGMS does not intend to use this award to support individuals who already have faculty appointments including assistant professor, clinical assistant professor, research assistant professor, and instructor or their equivalent in academia, industry, or elsewhere.

Exceptions to the Five-year Limit: In unusual circumstances, exceptions to the 5-year limit may be approved. An exception may be considered when a significant change in fields of study has occurred, such as moving from physical science to life science research, or when a significant break in training has occurred as a result of family responsibilities. Such unique exceptions will be considered on a case by case basis. Investigators are encouraged to contact NIGMS staff to discuss issues regarding eligibility prior to applying. In a cover letter with the application, the investigator should include an explanation of the special circumstances of his/her career training that warrants consideration for an exception. The applicant should provide similar information in the career development section of the application.

The NIMH welcomes applications from postdoctoral scientists seeking to establish an independent research career in areas of research supported by the Institute. The NIMH supports a broad spectrum of basic and translational research, including basic neuroscience and behavioral science, human genetics, adult and pediatric translational research, services and intervention research, and health and behavior and AIDS-related research (http://www.nimh.nih.gov/about/organization/nimh-extramural-research-programs.shtml). Prospective applicants are strongly encouraged to contact Institute career development staff (http://www.nimh.nih.gov/research-funding/training/training-development-contacts.pdf) before preparing an application to discuss the relevance of the proposed research to the Institute's research priorities and for guidance on the proposed research and career development plans.

Awardees are expected to complete at least one full year of mentored training under the K99 phase before transitioning to the R00 phase.

Prior to commencing the third year of the independent investigator (R00) award phase, NIMH awardees are expected to have submitted an investigator-initiated research grant (R01) application.

Salary Support: Normally salary up to $50,000 plus fringe benefits per year. Under certain circumstances, applicants may be eligible for up to $90,000 salary plus fringe benefits per year.

NINDS Specific Information:
Applicants are strongly encouraged to contact Dr. Korn with any questions about eligibility or other questions about the K99/R00 program. More information can be found on the NINDS website: http://www.ninds.nih.gov/funding/postdoc.htm#k99.

Salary Support: Normally, salary up to $50,000 plus fringe benefits per year. Under certain circumstances, applicants may be eligible for up to $85,000 salary.

NINR welcomes applications from postdoctoral scientists seeking to establish an independent research career on preventing, delaying the onset, and slowing the progression of disease and disability. This includes finding effective approaches to achieving and sustaining a healthy lifestyle, easing the symptoms of illness, improving quality of life for patients and caregivers, eliminating health disparities, and addressing issues at the end of life. NINR supports basic research relevant to its mission, in order to provide a sound scientific basis for changes in clinical practice. In keeping with the importance of translational research in various settings, NINR's major emphasis is on interdisciplinary research. NINR's research program is guided by four strategies intended to advance science:

integrating biology and behavior

designing and using new technology

developing new tools

preparing the next generation of nurse scientists

Central to the themes of our research are the important roles that the patient, the family and other caregivers, and the community play in promoting health and managing disease and disability. Science areas of particular interest include, but are not limited to, end of life, biobehavioral research, genetics, epigenetics, and incorporation of advanced technology. As our science grows, NINR is focusing on ways to stimulate its future development by incorporating new tools and analytical approaches such as informatics and meta-analyses. The role of interdisciplinary research teams is a priority and will continue to increase. The Institute is committed to training new investigators, with attention to the areas of greatest need and to strategies for encouraging young investigators and members of groups underrepresented into science.

NLM supports research career development in biomedical informatics and bioinformatics. We define informatics as the intersection of computer, information and behavioral sciences with one or more application domains. Application domains of interest include health care delivery, basic biomedical research, clinical and translational research, public health and others. Whatever the application domain, the research career focus must be informatics. Preference will be given to applicants who received their informatics training at one of NLM's university-based training programs in Biomedical Informatics.

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