Medical Xpress news tagged with:host cellhttp://medicalxpress.com/
en-usMedical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine.How a nasty, brain-eating parasite could help us fight cancerWe've known since the turn of the 20th century that some infectious diseases are a major risk for developing specific cancers. More worryingly, about one-sixth of cancers worldwide are attributable to infectious agents. Globally, more than 2m cancer cases are linked to certain carcinogenic viral, bacterial or parasitic agents. Two-thirds of these occur in developing countries.http://medicalxpress.com/news/2016-08-nasty-brain-eating-parasite-cancer.html
CancerFri, 26 Aug 2016 07:50:01 ESTnews391414833Bone marrow-derived stem cells offer blood transplant patients better quality of lifeA large, nationwide study published in the journal JAMA Oncology found that people who received transplants of cells collected from a donor's bone marrow the original source for blood stem cell transplants, developed decades ago had better self-reported psychological well-being, experienced fewer symptoms of a common post-transplant side effect called graft-vs.-host disease and were more likely to be back at work five years after transplantation than those whose transplanted cells were taken from the donor's bloodstream.http://medicalxpress.com/news/2016-08-bone-marrow-derived-stem-cells-blood.html
CancerTue, 16 Aug 2016 15:23:16 ESTnews390579784Scientists determine how gaseous substances in the human body affect psyche and behaviorProfessor Alexander Oleskin from the Lomonosov Moscow State University and colleagues have published a study in Microbial Ecology in Health and Disease devoted to the review of gaseous neurotransmitters of microbial origin and their role in the human body.http://medicalxpress.com/news/2016-07-scientists-gaseous-substances-human-body.html
Medical researchWed, 27 Jul 2016 07:08:04 ESTnews388822071Cord blood outperforms matched, unrelated donor in bone marrow transplantA University of Colorado Cancer Center study compared outcomes of leukemia patients receiving bone marrow transplants from 2009-2014, finding that three years post transplant, the incidence of severe chronic graft-versus-host disease was 44 percent in patients who had received transplants from matched, unrelated donors (MUD) and 8 percent in patients who had received umbilical cord blood transplants (CBT). Patients who received CBT were also more likely to no longer need immunosuppression and less likely to experience late infections and hospitalizations. There was no difference in overall survival between these two techniques. Results are published in the journal Bone Marrow Transplant.http://medicalxpress.com/news/2016-07-cord-blood-outperforms-unrelated-donor.html
OtherTue, 26 Jul 2016 17:46:10 ESTnews388773958Parasite proteins prompt immune system to fight off ovarian tumors in miceScientists identified the specific proteins secreted by the parasite Toxoplasma gondii that cause the immune system in mice to attack established ovarian tumors. The study, led by David Bzik of the Geisel School of Medicine at Dartmouth in Hanover, New Hampshire, is published on July 22 in PLOS Genetics.http://medicalxpress.com/news/2016-07-parasite-proteins-prompt-immune-ovarian.html
GeneticsFri, 22 Jul 2016 14:00:01 ESTnews388403103Potential drug target identified for Zika, similar virusesScientists potentially have found a way to disrupt Zika and similar viruses from spreading in the body.http://medicalxpress.com/news/2016-06-potential-drug-zika-similar-viruses.html
Diseases, Conditions, SyndromesFri, 17 Jun 2016 13:01:33 ESTnews385387283A new way to nip AIDS in the budWhen new AIDS virus particles bud from an infected cell, an enzyme named protease activates to help the viruses mature and infect more cells. That's why modern AIDS drugs control the disease by inhibiting protease.http://medicalxpress.com/news/2016-06-nip-aids-bud.html
HIV & AIDSThu, 09 Jun 2016 14:00:14 ESTnews384695428War and peace in the human gut: Probing the microbiomeHuman well being often flourishes under conditions of cooperation with others and flounders during periods of external conflict and strife.http://medicalxpress.com/news/2016-06-war-peace-human-gut-probing.html
Medical researchMon, 06 Jun 2016 16:34:09 ESTnews384449638New method gives scientists a better look at how HIV infects and takes over its host cellsViruses attack cells and commandeer their machinery in a complex and carefully orchestrated invasion. Scientists have longed probed this process for insights into biology and disease, but essential details still remain out of reach.http://medicalxpress.com/news/2016-05-method-scientists-hiv-infects-host.html
HIV & AIDSTue, 24 May 2016 06:54:58 ESTnews383291686Gene therapy against brain cancerOnly a few days ago, the press (especially in English-speaking countries) enthusiastically announced the publication of a study that described in great detail the genetics of breast cancer, a discovery that according to many marks a breakthrough in the battle against this cancer. This kind of news confirms the impression that in the near future the war against cancer will be fought on the battlefields of genetics. Italy too, is working on this front.http://medicalxpress.com/news/2016-05-gene-therapy-brain-cancer.html
CancerFri, 13 May 2016 09:34:51 ESTnews382350879An old new weapon against emerging Chikungunya virusSince 2013, the mosquito-borne Chikungunya virus has spread rapidly through South America and the Caribbean, and is now threatening Southern Europe and the southern US. It causes flu-like symptoms with fever and joint pains, which in some cases can last for months with occasional fatalities.http://medicalxpress.com/news/2016-05-weapon-emerging-chikungunya-virus.html
Diseases, Conditions, SyndromesThu, 12 May 2016 08:43:56 ESTnews382261333Counterattack of the hepatitis B virusThe hepatitis B virus (HBV), which is up to 100 times more infectious than HIV, is primarily transmitted through blood or other bodily fluids. HBV infects liver cells and chronic infection can lead to serious health problems such as cirrhosis or liver cancer. According to the World Health organization, chronic hepatitis B affects nearly 240 million people worldwide, killing almost 800,000 people a year. Drugs are available to treat HBV, but they rarely cure the infection, and so the virus typically returns after the treatment ends.http://medicalxpress.com/news/2016-03-counterattack-hepatitis-virus.html
Medical researchWed, 16 Mar 2016 14:00:01 ESTnews377351265New TSRI study shows HIV structure in unprecedented detail A new study from scientists at The Scripps Research Institute (TSRI) describes the high-resolution structure of the HIV protein responsible for recognition and infection of host cells.http://medicalxpress.com/news/2016-03-tsri-hiv-unprecedented.html
HIV & AIDSThu, 03 Mar 2016 14:00:11 ESTnews376233740Inside the hepatitis C virus is a promising antiviralA peptide derived from the hepatitis C virus (HCV) kills a broad range of viruses while leaving host cells unharmed by discriminating between the molecular make-up of their membranes, reveals a study published January 5 in the Biophysical Journal. The peptide was potent against a range of cholesterol-containing viruses, including West Nile, dengue, measles, and HIV.http://medicalxpress.com/news/2016-01-hepatitis-virus-antiviral.html
Diseases, Conditions, SyndromesTue, 05 Jan 2016 12:00:01 ESTnews371209699Scientists reveal new phase of HIV infectionResearchers at the University of Massachusetts Medical School have identified a new life cycle stage in HIV infection, thanks to a novel technique they developed to take images of intact infected cells. They've shown that this phase of infection, dubbed intra-nuclear migration, by principal investigator Abraham L. Brass, MD, PhD, relies on the human protein CPSF6 to guide the virus through the host cell's nucleus and position it at active genes where it prefers to make its home. Details of HIV's intra-nuclear migration and the imaging techniques used to find it were published in Cell Reports.http://medicalxpress.com/news/2015-12-scientists-reveal-phase-hiv-infection.html
HIV & AIDSWed, 16 Dec 2015 14:14:59 ESTnews369497675'Hijacking' and hibernating parasite could alter brain behaviorMelbourne researchers have discovered how a common parasite hijacks host cells and stockpiles food so it can lie dormant for decades, possibly changing its host's behaviour or personality in the process.http://medicalxpress.com/news/2015-12-hijacking-hibernating-parasite-brain-behavior.html
Medical researchWed, 09 Dec 2015 12:00:06 ESTnews368861519Human genomic pathways to bronchitis virus therapyViral replication and spread throughout a host organism employs many proteins, but the process is not very well understood. Scientists at A*STAR have led a collaborative study to learn which host factors play a key role in viral replication. The aim was to identify host pathways and processes that operate at various stages of infection by a bronchitis virus that could be targeted to fight viruses.http://medicalxpress.com/news/2015-11-human-genomic-pathways-bronchitis-virus.html
Diseases, Conditions, SyndromesWed, 18 Nov 2015 07:24:33 ESTnews367053859Blocking Ebola virus budding by regulating calcium signalingThe Ebola virus acts fast. The course of infection, from exposure to recovery, or death, can take as little as two weeks. That may not leave enough time for the immune system to mount an effective response.http://medicalxpress.com/news/2015-10-blocking-ebola-virus-budding-calcium.html
Medical researchFri, 30 Oct 2015 07:28:40 ESTnews365408866An antibody that can attack HIV in new waysProteins called broadly neutralizing antibodies (bNAbs) are a promising key to the prevention of infection by HIV, the virus that causes AIDS. bNAbs have been found in blood samples from some HIV patients whose immune systems can naturally control the infection. These antibodies may protect a patient's healthy cells by recognizing a protein called the envelope spike, present on the surface of all HIV strains and inhibiting, or neutralizing, the effects of the virus. Now Caltech researchers have discovered that one particular bNAb may be able to recognize this signature protein, even as it takes on different conformations during infection—making it easier to detect and neutralize the viruses in an infected patient.http://medicalxpress.com/news/2015-09-antibody-hiv-ways.html
HIV & AIDSFri, 11 Sep 2015 13:10:47 ESTnews361195839How long have primates been infected with viruses related to HIV?Disease-causing viruses engage their hosts in ongoing arms races: positive selection for antiviral genes increases host fitness and survival, and viruses in turn select for mutations that counteract the antiviral host factors. Studying such adaptive mutations can provide insights into the distant history of host-virus interactions. A study published on August 20th in PLOS Pathogens of antiviral gene sequences in African monkeys suggests that lentiviruses closely related to HIV have infected primates in Africa as far back as 16 million years.http://medicalxpress.com/news/2015-08-primates-infected-viruses-hiv.html
HIV & AIDSThu, 20 Aug 2015 14:00:08 ESTnews359293852Rabbit virus improves bone marrow transplants, kills some cancer cellsUniversity of Florida Health researchers have discovered that a rabbit virus can deliver a one-two punch, killing some kinds of cancer cells while eliminating a common and dangerous complication of bone marrow transplants.http://medicalxpress.com/news/2015-06-rabbit-virus-bone-marrow-transplants.html
Medical researchFri, 05 Jun 2015 19:17:37 ESTnews352750649Bladder cells regurgitate bacteria to prevent urinary tract infectionsDuke Medicine researchers have found that bladder cells have a highly effective way to combat E. coli bacteria that cause urinary tract infections (UTIs).http://medicalxpress.com/news/2015-05-bladder-cells-regurgitate-bacteria-urinary.html
Medical researchThu, 28 May 2015 12:00:11 ESTnews352018033Optical tweezers manipulate key protein involved in HIV infectionUsing an instrument so sensitive it can fold and unfold a single protein, Yale School of Medicine researchers have manipulated a protein essential for HIV to invade cells. The "optical tweezers" allowed researchers to apply tiny forces to a single protein that mediates entrance of HIV into host cells.http://medicalxpress.com/news/2015-05-optical-tweezers-key-protein-involved.html
HIV & AIDSTue, 19 May 2015 07:45:37 ESTnews351240321Safety switch preserves beneficial effects of cell therapyResearchers in the Center for Cell and Gene Therapy at Baylor College of Medicine, Houston Methodist and Texas Children's Hospital have found that a single dose of an otherwise harmless drug can safely control the severe and often lethal side effects associated with haploidentical stem cell transplantation.Due to the immune-compromising nature of haploidentical stem cell transplantation, where the stem cells are only half matched, patients are at an increased risk of viral infection and of a lethal complication called graft versus host disease, when the graft cells, which have immune potential, attack the tissues of the person whose original immune system has been eliminated as part of treatment. Investigators have now shown how a molecular "switch" (inducible caspase 9 or iC9) that is activated by a single dose of a bio-inert chemical is able to clear all symptoms of graft versus host disease without jeopardizing the ability of the infused graft to fight infection.http://medicalxpress.com/news/2015-05-safety-beneficial-effects-cell-therapy.html
Medical researchThu, 14 May 2015 10:00:02 ESTnews350807764Researchers identify new target for anti-malaria drugsA new target for drug development in the fight against the deadly disease malaria has been discovered by researchers at MIT.http://medicalxpress.com/news/2015-05-anti-malaria-drugs.html
Medical researchThu, 14 May 2015 06:21:17 ESTnews350803266New technology may reduce deadly complication of bone marrow transplantsResearchers have designed a way to mitigate graft-versus-host disease, a common and often life-threatening complication of bone marrow transplants that are used to treat leukemia and other blood cancers.http://medicalxpress.com/news/2015-05-technology-deadly-complication-bone-marrow.html
Medical researchTue, 12 May 2015 08:00:01 ESTnews350635170Macrophages as T-cell primersNew work by Ludwig-Maximilians-Universitaet (LMU) in Munich researchers demonstrates that macrophages can effectively substitute for so-called dendritic cells as primers of T-cell-dependent immune responses. Indeed, they stimulate a broader-based response.http://medicalxpress.com/news/2015-04-macrophages-t-cell-primers.html
ImmunologyWed, 15 Apr 2015 16:23:47 ESTnews348333820Using dengue virus as test case, biologists develop method for discovering drugs that interrupt viral proliferationA team of biologists from San Diego State University has developed a platform for identifying drugs that could prove to be effective against a variety of viral diseases. In a pair of recent articles in the Journal of Biomolecular Screening and the Journal of Visualized Experiments, the researchers describe how the methodology works, using dengue virus as an example, and they identify a novel drug which may someday be used to combat the disease.http://medicalxpress.com/news/2015-04-dengue-virus-case-biologists-method.html
Diseases, Conditions, SyndromesTue, 14 Apr 2015 00:00:01 ESTnews348163304Scientists identify receptor for asthma-associated virusScientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have identified a cellular receptor for rhinovirus C, a cold-causing virus that is strongly associated with severe asthma attacks. A variant in the gene for this receptor previously had been linked to asthma in genetic studies, but the potential role of the receptor, called CDHR3, in asthma was unknown. The new findings help clarify the function of CDHR3 and point to a novel target for the development of prevention and treatment strategies against rhinovirus C-induced colds and asthma attacks.http://medicalxpress.com/news/2015-04-scientists-receptor-asthma-associated-virus.html
Medical researchMon, 06 Apr 2015 16:06:21 ESTnews347555170Study shows two new flu strains do not yet easily infect humansScientists at The Scripps Research Institute (TSRI) have analyzed a key protein from two influenza strains that recently began causing sporadic infections among people in China and Taiwan.http://medicalxpress.com/news/2015-03-flu-strains-easily-infect-humans.html
Diseases, Conditions, SyndromesWed, 11 Mar 2015 12:00:05 ESTnews345287990