Primary tumor location as a predictor of the benefit of palliative resection for colorectal cancer with unresectable metastasis

Primary tumor location as a predictor of the benefit of palliative resection for colorectal cancer with unresectable metastasis - Download this document for free, or read online. Document in PDF available to download.

World Journal of Surgical Oncology

, 15:138

First Online: 27 July 2017Received: 28 October 2016Accepted: 03 July 2017

Abstract

BackgroundIt is still under debate that whether stage IV colorectal cancer patients with unresectable metastasis can benefit from primary tumor resection, especially for asymptomatic colorectal cancer patients. Retrospective studies have shown controversial results concerning the benefit from surgery. This retrospective study aims to evaluate whether the site of primary tumor is a predictor of palliative resection in asymptomatic stage IV colorectal cancer patients.

MethodsOne hundred ninety-four patients with unresectable metastatic colorectal cancer were selected from Sun Yat-sen University Cancer Center Database in the period between January 2007 and December 2013. All information was carefully reviewed and collected, including the treatment, age, sex, carcinoembryonic antigen, site of tumor, histology, cancer antigen 199, number of liver metastases, and largest diameter of liver metastasis. The univariate and multivariate analyses were used to detect the relationship between primary tumor resection and overall survival of unresectable stage IV colorectal cancer patients.

ConclusionsThis study showed that left-side colon cancer patients might benefit from the primary tumor resection in terms of overall survival. This result should be further explored in a prospective study.

* Images in this website could be protected under copyright laws. They are picked automatically from bing.Please use the contact form to claim a copyright infriction and the item will be removed immediatelly.