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REUTLINGEN, Germany, Feb. 19, 2013 /PRNewswire/ -- Retina Implant AG, the leading developer of subretinal implants for patients blinded by retinitis pigmentosa (RP), today announced results from part of its multicentre study were published today in the peer-reviewed journal Proceedings of the Royal Society B. The research found that, during the course of a three to nine month observation period, functional vision was restored in the majority of nine German patients implanted with a subretinal microchip as part of the first module of the Company's second human clinical trial. In addition, visual acuity for two of the nine patients surpassed the visual resolution of patients from the Company's first human clinical trial.

The study titled "Artificial Vision with Wirelessly Powered Subretinal Electronic Implant Alpha IMS" was led by researchers at the University Eye Hospital in Tuebingen, Germany including Professor Eberhart Zrenner and Katarina Stingl, M.D. Patients were implanted with Retina Implant AG's subretinal wireless 3x3 mm2, 1500 pixel Alpha IMS microchip and are able to adjust the level of stimulation received to view objects at varied distances. Of the nine patients observed in the study, three patients were able to read letters spontaneously. During observation in and outside the laboratory patients also reported the ability to recognize faces, distinguish objects such as telephones and read signs on doors.

"The results of our first human clinical trial exceeded our expectations, and we are further encouraged by the results from the second human trial," said Professor Eberhart Zrenner, M.D., lead clinical trial investigator, Institute for Ophthalmologic Research at University Eye Hospital Tuebingen, Germany. "As physicians, we are constantly seeking out the best treatment options for our most in-need patients, which most definitely includes those suffering from advanced-stage retinitis pigmentosa. This research provides additional evidence that our subretinal implant technology can help some patients with retinal degeneration regain functional vision and does so in a way that does not require externally visible equipment."

"The continuation of our trial and publication of this module is the next milestone in our quest to secure CE mark approval and provide RP patients living in darkness with a treatment option," said Walter-G. Wrobel, president and CEO, Retina Implant AG. "We are continually humbled by the 36 patients we've implanted thus far and their willingness to participate in this ground-breaking research."

The Company's first clinical trial began in Germany in 2005, where 11 patients suffering from retinitis pigmentosa were implanted with a subretinal microchip below the retina in the macular region. Results from the first trial were published in November 2010 in Proceedings of the Royal Society B, concluding that the implantation of Retina Implant's microchip was successful in restoring useful vision in patients previously blind due to retinitis pigmentosa. The second clinical trial with a wireless device that allows patients to use the implant outdoors and at home began in May 2010 in Tuebingen, Germany, and has since expanded into the multicentre phase of the trial with implants taking place in Hong Kong and the UK.

"As a leading relevant patient organisation in the UK we have been watching Retina Implant AG's research with great interest," said David Head, CEO of RP Fighting Blindness. "The results published today show definite promise to one day restore functional vision to patients with advanced-stage retinitis pigmentosa."

About Retinitis PigmentosaRetinitis pigmentosa (RP) is one of the most common forms of inherited retinal degenerations affecting 1.5 million worldwide. A progressive condition that gets worse over time, RP typically causes severe vision problems in adulthood. Retinal implants represent promise for enabling RP patients to regain functional sight.

About Retina Implant AGRetina Implant AG is the leading developer of subretinal implants for partially sighted and blind patients. After extensive research with German university hospitals and institutes which began with a large grant from the German Federal Ministry of Research and Education in 1996, Retina Implant AG was founded by Dr. Eberhart Zrenner and his colleagues in 2003 with private investors with the goal of developing a fully-functioning electronic retinal implant to restore useful vision to the blind. Retina Implant began implanting in human patients in 2005 and started a second clinical trial in 2010. To learn more, visit: http://www.retinaimplant.de/.

About Royal Society PublishingThe Royal Society is a self-governing Fellowship of many of the world's most distinguished scientists drawn from all areas of science, engineering, and medicine. The Society's fundamental purpose, as it has been since its foundation in 1660, is to recognise, promote, and support excellence in science and to encourage the development and use of science for the benefit of humanity.

The Society's strategic priorities emphasise its commitment to the highest quality science, to curiosity-driven research, and to the development and use of science for the benefit of society. These priorities are:1. Promoting science and its benefits2. Recognising excellence in science3. Supporting outstanding science4. Providing scientific advice for policy5. Fostering international and global cooperation6. Education and public engagement

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