Rates of women who are opting for preventive mastectomies, such as Angeline Jolie, have increased by an estimated 50 percent in recent years, experts say. But many doctors are puzzled because the operation doesn't carry a 100 percent guarantee, it's major surgery -- and women have other options, from a once-a-day pill to careful monitoring.

April Godra, a shelter official, said she knew something wasn’t right when Foxie, a normally quiet collie, would not stop barking as Godra made her rounds through the northwestern Indiana kennels two weeks ago.

Then she noticed Foxie looking at the door leading to the garage where the dogs were.