Wayward Frankenstein (2010)
(Short)
Frankenstein says he knows the meaning of life is '42' this is the answer the the ultimate question of life the universe and everything from the hitch hikers guide to the galaxy.

TableTop: Star Fluxx (2012)
(TV Episode)
One of the goals is called "Forty-Two" and references Deep Thought and the Guide

Mama (2013)
Annabel sarcastically asks if the men looking for the two girls are going to check area "Z-Z-9-Plural-Z-Alpha", the exact name given to reference the Earth's location in the Universe, on board the Heart Of Gold.

Alice Through the Looking Glass (2016)
When Alice mumbles "I once believed i could do six impossible things before breakfast", it is a reference to the marketing slogan of "Milliways" - The Restaurant at the End of the Universe.

Spoofs

Spoofed in

Space Quest 1: The Sarien Encounter (1990)
(Video Game)
The depressed weapons droid aboard the Deltaur is a parody on Marvin, the paranoid android. The Sariens resemble the Vogons.

Quest for Glory I: So You Want to Be a Hero (1992)
(Video Game)
One of the questions the gargoyle asks is "What is the meaning of life, the universe, and everything?". The correct answer is 42, to which the gargoyle replies "So you put some Deep Thought into the question, eh?".

Spaced: Beginnings (1999)
(TV Episode)
When Tim starts talking about Daisy's fear that mice may crossbreed with spiders to create a hybrid, an animated sequence comes on screen to demonstrate the creature which spoofs the animated sequences from the guidebook in this mini series. The style of animation is the same (green lines on a green grid with a black background).

The Hitchhiker's Guide to the Galaxy (2005)
When Arthur, Zaphod and Ford are working their way through the line on the planet Vogsphere, Arthur passes Marvin from the miniseries and does a double take as he walks by.