Compared to this selection my first two choices are mundane and somewhat predictable.

Braquo(Capa Drama) is a French cop show and a placeholder for any non-procedural crime story. I mean some kind of anti-CSI, etc. Yes, I know there is Mutant City Blues (Pelgrane Press) and the GUMSHOE system. I mean something different. Braquo is more character-driven. These desperate cops are corrupt. They do what is needed to done. The lines between good and evil or law and crime blur. As I mentioned before, Braquo is a placeholder. Think Internal Affairs, Donnie Brasco or the obscure, but highly recommended New World. Undercover cops, temptation and betrayal. Excellent roleplaying stuff in my opinion.

Mass Effect (Bioware). Bioware’s Dragon Age is nice and the pen & paper version by Green Ronin is good. Thedas is for me D&D mixed up with some Game of Thrones tropes. The Witcher series and Mass Effect play in another league. The Witcher Roleplaying Game (CD Project Red/Talsorian Games) has been announced a few days ago.
The first Mass Effect is one of the best cRPGs I’ve ever played, because it is mature and you have to do some though decisions. The game is closer to the brilliant Babylon 5 series than to $tar War$ or Star Trek. The last intellectual properties are extremely popular and I ‚hate‘ them for their ‚disneyfication‘ – good clean family fun without any rough edges and corners. Mass Effect touches themes like genocide in a different way. The ‚incidental‘ destruction of Alderaan means nothing to the audience. I don’t start to rant about the ridiculous ‚Han shot first‘ edit. The opportunity to kill the Rachni Queen in Mass Effect is a different sport – at least for me.

Honorable mention: The Bordertown series (originally edited by Terri Windling and Mark Alan Arnold), a rare and early shared urban fantasy series.

„Bordertown, a city on the border between our human world and the elfin realm. Where both magic and technology refuse to follow anyone’s rules. Where Elves play in rock bands and race down the street on spell-powered motorbikes. Where human kids recreate themselves in the squats and clubs and artists‘ studios of Soho.

Bordertown, where runaway teens from both sides of the border come to find adventure, and to find themselves.

Bordertown, where nothing is ever quite what it seems.“
– Bordertown teaser text (9th August 2015)

Chummers or super smart Shadowrunners, Borderland, the first book, was published 1986. Your game came out 1989. Any further questions?