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Biological Network Visualisation

Kai Xu (Middlesex University, London, UK)

This poster shows a series of biological network visualisations. The first example is for Gene Ontology analysis. Instead of a list of ‘significant’ functions with their p-values, the result is shown as a network: the blue nodes are genes, which link to their functions (green nodes). The green nodes are linked according to their relationships in GO hierarchy. The middle image shows such a network with a force-directed network layout and the right one with a hierarchical layout. The ‘multivariate network’ visualisation uses 3D surfaces to show numerical attributes of network nodes. The surface height above a node shows its attribute value. The top example uses two surfaces (red and blue) for two attributes. The bottom example is the Protein-Protein Interaction network of yeast and the attribute is node degree (i.e., number of connections). The ‘overlapping network’ visualisation places two related networks on parallel planes and link common nodes with inter-plane edges. Optionally, a third plan can be added in the middle to highlight the comment nodes and edges. The bottom example shows a Protein-Protein Interaction network and a related metaboli