Windows: We've been waiting for multiple profile support in Chrome for a long time, and if you have a copy of the bleeding-edge Canary build, you can try Google's official—and rather polished—built-in profile support now.

Windows only: If you're a Chrome fan and want to see the very latest in features and fixes,…
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Chrome's multiple profile support has always been pretty difficult to maneuver, and while there were a few options out there like ChromeDeck, Google Chrome Profile Backup, or just running Chromium alongside Chrome, the support Google's building into Chrome looks pretty darn nice. Just fire up Canary, head into about:flags and enable the Multiple Profiles flag, and then head to Chrome's Settings > Personal Stuff to set up your profiles. Your profiles will be connected to Google accounts, so you'll need more than one for it to work.

Windows: Google's Chrome browser doesn't have nearly the same kind of user profile…
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Right now, the feature doesn't seem quite complete. The drop-down window that appears in the upper right hand corner tells you what profile you're using, but doesn't show your other profiles in the list. However, if you just open up a new window and head back into the settings, disconnect it from the current profile and re-connect it to your other account, you'll have two separate instances of Chrome, each using the settings you've synced to their respective Google Accounts.