1. Hoyer out: Quarterback Brian Hoyer, who injected life into the offense the last two games, suffered a right knee injury on the game’s second drive. Coach Rob Chudzinski called it a sprained knee, but it could be much worse. Hoyer will have an MRI done later today. He left the locker room on crutches with a brace on his knee.

2. Run over: After four solid games defending the run, the Browns allowed the Bills to rush for 155 yards on 31 carries. C.J. Spiller motored for a 54-yard touchdown.

3. Weeden struggles: What’s this, the same player appearing in both categories? While making his share of big plays, he also showed some familiar flaws, including a lack of pocket presence. He was fortunate Joe Thomas recovered a third-quarter fumble. Weeden was sacked five times.

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