Patient Participation in Clinical Trials Infographic

In December, we published our first infographic.Our goal was to start a discussion around the
question: "How often do patients receive placebos in cancer clinical trials?" After digging into the data from
cancer trials registered on ClinicalTrials.gov, we found less than a 1 percent chance of a patient
receiving a placebo alone on a cancer study. The majority of placebo-based trials administer the placebo along
with standard of care treatments.

We received some great constructive feedback on the graphic from the patient advocacy and clinical research
communities through our blog and Twitter. We appreciate those who asked clarifying questions and gave us
suggestions for future infographics. Armed with their input, we went to work on our second infographic.

Patient Participation in Clinical Trials

For this one, we decided to cast the net a little wider. We wanted to find out why people do and do not participate
in clinical trials and present that information in an easy-to-read and easy-to-share format. We think that focusing
on this topic could help to both alleviate some misconceptions patients may have about clinical trials, and help
researchers to understand what areas of communication they should focus on improving in order to make the clinical
trial experience better for participants.

One of the first things we learned in the process of the gathering statistics for this infographic, is that general
lack of awareness about clinical trials among patients is a major issue. According to a study published in The Journal of
Community Oncology, only 16 percent of cancer patients know that clinical trials are an option they could explore;
however, once patients do learn about clinical trials, 43 percent of those who are eligible do so.

Of course, there are several other reasons that patients don't participate in clinical trials. Some of those
reasons include...

the fear of receiving a placebo,

the fear of potential side effects,

the worry that the standard treatment will be better than the drug being studied, and

concerns about insurance coverage.

By bringing these concerns to light, and being transparent with information about the challenges and rewards that
may come with clinical trial participation, we can help patients make the best possible decisions about their
healthcare, whether that includes participating in a study or not.

Increasing Awareness

According to a 2013 Perceptions and Insights study from CISCRP, 95 percent of those who have participated in a
clinical trial say they'd consider joining another one.This seems to indicate that most of those who did decide to
participate in clinical research had a positive experience. So now, the question is, how do we make sure that
large numbers of patients who aren't currently aware of clinical trials have a chance to learn about research
opportunities?

We believe that creating infographics such as this one, and openly sharing information on clinical trials in social
media are small steps toward the goal. What other steps do you think could be taken to increase awareness of
clinical trials? And, what do you think of our latest effort? Please comment here or give us a shout on Twitter.