EMBARGOED UNTIL 11:00 a.m. ET, Nov. 16, 2018, CLEVELAND: A Cleveland Clinic genetic analysis has found that obesity itself, not just the adverse health effects associated with it, significantly increases the risk of Type 2 diabetes and coronary artery disease. The paper was published today in the Journal of the American Medical Association Network Open .
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The American Heart Association and Allen Institute announce $43 million commitment in research funding for innovative approaches to combat age-related dementia, including Alzheimer's disease Could our blood hold the molecular secrets to a fountain of youth, preventing age-related brain disorders? Are brain aging and Alzheimer's disease caused by a failure of interconnected systems in our bodies, triggering a domino-like cascade of disease? Can targeting the red blood cells and blood vessels jointly keep our brains healthy and prevent dementia? Three new large-scale, multidisciplinary research teams have just been assembled to answer those questions.
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October 17, 2018, Cleveland: Charis Eng, M.D., Ph.D., chair of Cleveland Clinic's Genomic Medicine Institute, is receiving the American Cancer Society's Medal of Honor, the organization's highest award. An internationally recognized physician-scientist in the cancer genetics field, Dr. Eng is among five honorees to receive the award at a ceremony in Washington, D.C. on October 18. The ACS Medal of Honor is presented to individuals who have made outstanding and valuable contributions in the field of cancer.
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Tuesday, Oct. 9, 2018, CLEVELAND: The National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the National Institutes of Health , has awarded Cleveland Clinic $6 million to study techniques used for anterior cruciate ligament reconstruction. The five-year grant - led by principal investigator Kurt P. Spindler, M.D., of Cleveland Clinic and founder of the Multicenter Orthopaedic Outcomes Network Group - supports a multi-center, randomized clinical trial aimed at determining if outcomes of a new surgical technique, Bridge-Enhanced ACL Repair , are equal to or better than outcomes of traditional ACL reconstruction surgery.
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Monday, October 1, 2018, CLEVELAND: Cleveland Clinic is the first hospital in the country to successfully perform surgeries using the Single Port SP Robot, which inserts all surgical instruments through one small abdominal incision, improving surgical outcomes and allowing quicker patient recovery. On Friday, Cleveland Clinic surgeons used the SP Robot to perform three surgeries - two surgeries to remove cancerous prostates and one surgery to remove an enlarged prostate blocking the urinary system through the bladder.
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Cleveland Clinic's Medical Innovation Summit will bring together more than 100 speakers and leaders from more than 500 organizations and 20 countries to downtown Cleveland on Oct. 22 to 24, 2018, focusing on the theme of Disruption: Reimaging Healthcare. Now in its 16th year, the annual Medical Innovation Summit is organized by Cleveland Clinic Innovations, the development and commercialization arm of Cleveland Clinic.
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The Gerontological Society of America -- the nation's largest interdisciplinary organization devoted to the field of aging -- has chosen Carol Whitlatch, PhD, FGSA, of the Center for Research and Education of the Benjamin Rose Institute on Aging in Cleveland, Ohio, as the 2018 recipient of the M. Powell Lawton Award. This distinguished honor recognizes a significant contribution in gerontology that has led to an innovation in gerontological treatment, practice or service, prevention, amelioration of symptoms or barriers, or a public policy change that has led to some practical application that improves the lives of older persons.
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EMBARGOED UNTIL 9:30 AM ET on August 28, 2018, Munich, Germany: Researchers at Cleveland Clinic, University of Oxford and University of Erlangen have identified a novel imaging biomarker, which has been found to be able to predict all-cause and cardiac mortality by measuring inflammation of fatty tissue surrounding the coronary arteries. Coronary artery inflammation inhibits fatty tissue formation surrounding the blood vessels, known as perivascular fat.
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August 21, 2018, Cleveland: Cleveland Clinic researchers have discovered a new subtype of multiple sclerosis , providing a better understanding of the individualized nature of the disease. MS has long been characterized as a disease of the brain's white matter, where immune cells destroy myelin - the fatty protective covering on nerve cells.
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A multidisciplinary research team led by Case Western Reserve University School of Medicine has received a three-year, $936,000 grant to use collaborative computational modeling approaches to promote better community health through more equitable food systems. Under the Tipping Points grant from the nonprofit Foundation for Food and Agriculture Research , a team led by Darcy Freedman, PhD, associate professor of population and quantitative health sciences at Case Western Reserve University School of Medicine, will conduct the Modeling the Future of Food in Your Neighborhood study that will examine several key food-system strategies.
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The Harrington Discovery Institute at University Hospitals in Cleveland, Ohio--part of The Harrington Project for Discovery & Development--has announced three new scholars in collaboration with its partners Foundation Fighting Blindness and Alzheimer's Drug Discovery Foundation . Harrington Discovery Institute collaborates with FFB on the Gund-Harrington Award to accelerate therapies for retinal degenerative diseases and ADDF to advance the development of drugs to prevent and treat Alzheimer's disease.
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Aug. 8, 2018, Cleveland: The National Heart, Lung and Blood Institute , part of the National Institutes of Health, awarded a $4.7 million grant to Cleveland Clinic to study the prevention of life-threatening, cancer-associated blood clots. The new funding will support a Cleveland Clinic-led research consortium, which will focus on developing strategies to prevent cancer-associated thrombosis , a potential side effect of cancer treatment.
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EMBARGOED UNTIL 11:00 a.m. ET, August 6, 2018, CLEVELAND: Cleveland Clinic researchers have designed a potential new class of drugs that may reduce cardiovascular risk by targeting a specific microbial pathway in the gut. Unlike antibiotics, which non-specifically kill gut bacteria and can lead to adverse side effects and resistance, the new class of compounds prevents microbes from making a harmful molecule linked to heart disease without killing the microbes, which are part of the gut flora and may be beneficial to overall health.
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Physicians continue to recommend routine self-monitoring of blood glucose for patients with non-insulin treated type 2 diabetes, in spite of its lack of effectiveness, because they believe it drives the lifestyle change needed to improve glycemic control. Researchers conducted a qualitative study of 17 primary care physicians exploring to what extent and why physicians still prescribe self-monitoring of blood glucose when the evidence shows that it increases costs without improving HbA1c, general well-being, or health-related quality of life.
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Research aims to identify differences in survival among heart failure patients before and after heart transplantation, as well as create tools to improve outcomes Monday, July 9, 2018, CLEVELAND: The National Institutes of Health has awarded Cleveland Clinic researcher Eileen Hsich, M.D., $2.8 million over four years to evaluate disparities in survival among heart failure patients before and after heart transplantation and to create tools that would optimize outcomes. "We believe that to improve care for those with heart failure awaiting transplant, we must better understand how differences among patients affect the timing of transplants and survival.
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IMAGE: The transmission electron microscopic image on the left is a collapsed perinexus in the heart of a person without atrial fibrillation. The image on the right is an expanded perinexus... view A collaborative research team is on a quest to collapse a tiny pocket between cardiac cells that can cause big problems.
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May 30, 2018, Cleveland: New Cleveland Clinic research shows for the first time that ibrutinib, an FDA-approved drug for lymphoma and leukemia, may also help treat the most common - and deadliest - type of brain tumor. The findings, published in Science Translational Medicine , offer hope that the drug may one day be used in patients with glioblastoma and improve poor survival rates.
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Friday, May 18, 2018, San Francisco: A multi-center study that validates the clinical performance of IsoPSA - a new blood test that has proven to be more accurate in predicting overall risk of prostate cancer than standard prostate-specific antigen - will be presented during a special press conference at the 13th Annual Meeting of the American Urological Association on May 18 in San Francisco. Results showed that more than 40 percent of biopsies could have been avoided in both the preliminary study and validation study , suggesting that use of IsoPSA may substantially reduce the need for biopsy, and may thus lower the likelihood of overdetection and overtreatment of nonlethal prostate cancer.
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