Been running from 6-8GB over 2 years now and only one program gave me a issue and that was Titans Quest. And before that when i was using 4GB of ram i just put it on another HDD which still would not be on a SSD.

Indexing on a SSD your kidding right ?. By time it's read the indexing files it most likly found the file anyways.

Absolute silence without compromising performance is my only benchmark score.

I'm not sure if ESET is using any scan optimizations in their antivirus but others like Kaspersky, Symantec and avast! utilize internal scan cache so the files that were scanned aren't repeatedly scanned again, reducing scan overhead significantly but also not decreasing security in any way (the file is scanned again if modified or if there is a new update available, permanent cached files are not scanned until modified, these are internally whitelisted). Otherwise read on SSD doesn't decrease its lifespan. Only (over)writting does.