Dr. Gambone is a reproductive endocrinologist and professor emeritus at the David Geffen School of Medicine at UCLA

Joseph Gambone DO MPH
Dr. Gambone is a reproductive endocrinologist and professor emeritus at the David Geffen School of Medicine at UCLA. He was awarded a Masters of Public Health degree from the UCLA School of Public Health in 1999. He is the author of over 100 scientific articles and book chapters and is executive editor of the fifth edition of Essentials of Obstetrics and Gynecology.
“We live in a very health-hostile environment that is just as hazardous to our health and quality of life as early man’s environment was to his very survival. It’s just a lot more difficult to recognize the risks of our current hostile environment than when an animal is trying to make you his dinner. This website and our books will help you to realize that modern life’s conveniences are costing us dearly.”

Lack of exercise is a common characteristic of men with ED, and embarking on an exercise program has been shown to help ED. Exercise makes the body more sensitive to insulin. Insulin is one of the body’s natural stimulants of nitric oxide (NO), the body chemical most responsible for healthy erections.

Excess weight, particularly if it is concentrated in the abdomen (the spare tire), interferes with erectile function in several ways. The most important effect of excess weight is that it causes resistance of the body’s tissues to insulin.

How The Penis Works The penis is just a collection of specialized blood vessels within a tough outer sheath of connective tissue. Sexual arousal causes blood to flow into the penis by releasing NO (Nitric Oxide) from the nerves supplying the penile arteries.

Over the past two decades, research from Dr. Ignarro’s laboratory and others has made the biochemistry and physiology of nitric oxide (NO) one of the most extensively studied and one of the most fundamentally important processes in the human body.