Don't call it flyover territory. The Midwest offers what top metros lack—plenty of space for one-of-a-kind luxury residences.

For the tens of millions of Americans not from the Midwest, the country’s heartland is little more than a collection of a dozen flyover states, beaded with crops, manufacturing plants, and small communities and bereft of the cosmopolitan allure of major cities like Los Angeles, New York City, and Miami.

And yet, far from common suppositions, the Midwest vaunts its own brand of unmissable flair. Compared to big-city residences, where homes often have limited square footage and little outdoor space, the most luxurious houses in the Midwest offer vast acreage, unheard-of square footage, and first-class features that can’t always be found in crammed metros.

“You get more overall, in house, setting, and amenities, for the money,” say Wayne Norwood and Ben Patton, who head the Finest Homes of St. Louis boutique team at Janet McAfee Real Estate. From Minnesota to Missouri, the following five estates represent the best of the Midwest.