What event in 1815 caused Beethoven to turn his energy away from composition and cost him his peace of mind for several years?

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He was awarded joint custody of his nephew upon the death of his brother.
His first and only opera turned out to be a huge flop.
After instructing Beethoven in the art of composition for a short time, Haydn turned against the young composer, citing a lack of creativity.
Beethoven discovered that he was losing his hearing and would eventually become completely deaf.