GTA V to feature THREE main protagonists.
http://www.gameinfor...eft-auto-v.aspx
I'm kinda iffy on the idea of three different main protagonists but I have faith in Rockstar to make it work.
Edit: Here's the entire 23 page reveal from Game Informer.
http://fast1195.imgur.com/grand_theft_auto_5_gi_reveal

3 days after the 1 year anniversary of the first trailer, the second is announced. I can't wait.
http://www.rockstargames.com/newswire/article/46031/grand-theft-auto-v-trailer-2-coming-next-week-wed-nov-14.html

A few different artwork pieces have leaked over the last few days from a couple different game retailers from Europe. Rockstar hasn't come out and said whether these are fakes or not but they have been deleting all comments mentioning the pieces on their website.
Looks like we'll be seeing GTA V in the spring.