Application Information: YAP1 antibody, C-term

Recommended Starting Dilutions:ELISA: Use at 1:1,000WB: Use at 1:50-100FACS: Use at 1:10-50Optimal dilutions should be determined experimentally by the researcher.

Predicted Target Size

48.755 kDa (note)

Form Supplied

Liquid

Concentration

0.25
mg/ml
(Please refer to the vial label for the specific concentration)

Purification

Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Specifications: YAP1 antibody, C-term

Full Name

Yes-associated protein 1

Product Description

Rabbit polyclonal to YAP1 (C-term)

Background

This gene encodes the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. This protein contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction. [provided by RefSeq]

Both phosphorylation and cell density can regulate its subcellular localization. Phosphorylation sequesters it in the cytoplasm by inhibiting its translocation into the nucleus. At low density, predominantly nuclear and is translocated to the cytoplasm at