Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

]]>01:13:32cleanmobile,culture,independent,global,natural,products,type,gene,antibiotics,iv,transfer,dna,microbe,conjugation,microbiology,bacterial,horizontal,microbiome,secretion,malacidin,relaxaseThe TWiMmers discuss culture-independent discovery of malacidin antibiotics, and unfolding of relaxase during bacterial conjugation.172fullVincent Racaniello171: If you give a bee a fungusIf you give a bee a fungusThu, 22 Feb 2018 18:54:01 +0000The TWiM team explores a stingless bee that requires a fungal steroid to pupate, and colonic biofilms containing tumorigenic bacteria in patients with colorectal polyps.

]]>The TWiM team discusses the use of copper on exercise weights to reduce bacterial burden, and the mechanism of antigenic variation by which a fungus that causes severe pneumonia escapes the immune system.

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This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com

]]>The TWiM hosts and associated microbiomes review a fungus destroying salamanders in Europe, and genes for flagella in intracellular bacteria.

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This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com

]]>From the TWiM team, a discussion of Hurricane Harvey microbiology, and a bacterial enzyme that induces eukaryotic mating.

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com

]]>55:56clean161fullVincent Racaniello, Michael Schmidt, Michele Swanson, Elio Schaechter.TWiM #160: On the road to virusOn the road to virusFri, 08 Sep 2017 05:20:09 +0000The TWiM team provides an update on Zika virus, and reveals a plasmid on the road to becoming a virus.

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com

]]>The TWiM team provides an update on Zika virus, and reveals a plasmid on the road to becoming a virus.

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com

]]>01:07:04cleanevolution,microbes,mosquito,microbiology,archaea,zika,microcephaly,plasmidThe TWiM team provides an update on Zika virus, and reveals a plasmid on the road to becoming a virus.
160fullVincent Racaniello, Michael Schmidt, Michele SwansonTWiM #159: Immunophage synergyImmunophage synergyThu, 31 Aug 2017 21:14:01 +0000The TWiM team pays a tribute to Chris Condayan, and investigates the synergy between virus and the innate immune system for clearing bacterial pneumonia by phage therapy.]]>The TWiM team pays a tribute to Chris Condayan, and investigates the synergy between virus and the innate immune system for clearing bacterial pneumonia by phage therapy.]]>01:00:36clean159fullVincent Racaniello, Elio Schaechter, Michael Schmidt, Michele SwansonTWiM #158: The bottom lineThe bottom lineThu, 10 Aug 2017 21:22:52 +0000The TWiM team considers a report on prokaryotic viral DNA in mammalian brain, and how diarrhea is beneficial, by clearing enteric pathogens.

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]]>01:05:01cleanbrain,evolution,viral,bacteria,tight,synapse,junction,microbe,microbiology,pathogen,synaptic,diarrhea,bacteriophage,prion,microbiome,intestinal,tse,citrobacter,neurodegenerative,sphinx1,boutons,claudin,il22prokaryotic viral DNA in mammalian brain, and how diarrhea is beneficial, by clearing enteric pathogens.158fullVincent Racaniello, Michael Schmidt, Elio Schaechter, Michele SwansonTWiM #157: Back to the ancestorBack to the ancestorThu, 27 Jul 2017 21:50:32 +0000The TWiMbionts explore the role of bacteria in the genesis of moonmilk, and how ancient host proteins can be used to engineer resistance to virus infection.

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]]>56:43cleanqueen,engineering,red,calcium,resistance,factor,bacteria,virus,cave,subterranean,microbe,microbiology,bacteriophage,microbiome,carbonate,precambrian,streptomyces,moonmilk,karstic,speleotherm,actinobacteria,biomineralization,hypogean,thioredoxin,proviralThe TWiMbionts explore the role of bacteria in the genesis of moonmilk, and how ancient host proteins can be used to engineer resistance to virus infection.157fullVincent Racaniello, Elio Schaechter, Michele Swanson TWiM #156: Gifted microbes and defensive symbiosisThu, 13 Jul 2017 19:18:14 +0000The TWiM team explains the use of microbial genome mining to identify new drugs, and how a bacterial symbiont protects flies against parasitoid wasps.

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

]]>57:56cleanTWiM #155: Living in the stomach of a cell Thu, 29 Jun 2017 22:49:06 +0000Michele updates the TWiMers on Legionella in the Flint water supply, and Elio informs us about how horizontally acquired biosynthesis genes boost the physiology of Coxiella burnetii.

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

]]>57:28cleanTWiM #154: Rigor, lotteries, and moonshotsWed, 14 Jun 2017 22:02:34 +0000At Microbe 2017 in New Orleans, the TWiM team speaks with Arturo Casadevall about his thoughts on the pathogenic potential of a microbe, rigorous science, funding by lottery, and moonshot science.

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]]>01:14:22cleanTWiM #153: Covert pathogenesisTue, 30 May 2017 19:19:22 +0000The TWiM team ventures into preprint space with an analysis of type VI secretion across human gut microbiomes, and provide insight into urinary tract infection: how bladder exposure to a member of the vaginal microbiota triggers E. coli egress from latent reservoirs.

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]]>The TWiM team ventures into preprint space with an analysis of type VI secretion across human gut microbiomes, and provide insight into urinary tract infection: how bladder exposure to a member of the vaginal microbiota triggers E. coli egress from latent reservoirs.

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

]]>57:35cleanTWiM #152: Wooden stepsFri, 19 May 2017 01:23:15 +0000The TWiMmers get cozy with symbionts: the bacteria that allow a giant shipworm to oxidize sulfur, and algae that live within salamander cells.

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]]>51:09cleanTWiM #151: Bat and moth antimicrobialsThu, 04 May 2017 21:32:12 +0000The TWiMsters discuss potential new sources of antimicrobial compounds from unusual places: the skin of bats and the intestines of moths.

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

]]>59:49cleanTWiM #150: Microbiology is where it’s atThu, 20 Apr 2017 23:41:00 +0000In recognition of National Medical Laboratory Professionals Week, Robin Patel speaks with the TWiM team about directing a clinical bacteriology laboratory, and how an observation made by a laboratory technologist lead to the finding thatUreaplasmaspecies can cause a system metabolic disturbance, hyperammonemia.

]]>In recognition of National Medical Laboratory Professionals Week, Robin Patel speaks with the TWiM team about directing a clinical bacteriology laboratory, and how an observation made by a laboratory technologist lead to the finding that Ureaplasma species can cause a system metabolic disturbance, hyperammonemia.

]]>01:01:21cleanTWiM #149: You’re going to learn RThu, 06 Apr 2017 21:56:52 +0000The TWiM team speaks with Pat Schloss about assigning sequence data to operational taxonomic units, and his experience with mSphere Direct, a new way of submitting papers for publication.

This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free – WITH FREE SHIPPING – by going to blueapron.com/twim

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

]]>The TWiM team speaks with Pat Schloss about assigning sequence data to operational taxonomic units, and his experience with mSphere Direct, a new way of submitting papers for publication.

This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free – WITH FREE SHIPPING – by going to blueapron.com/twim

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

]]>01:02:54cleanTWiM #148: Neanderthal DentistryThu, 23 Mar 2017 21:01:25 +0000Vincent, Elio, and Michael reveal what Neanderthals ate from analysis of DNA in their teeth, and new CRISPR-Cas systems found in the genomes of uncultured microbes.

This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free – WITH FREE SHIPPING – by going to blueapron.com/twim

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

]]>Vincent, Elio, and Michael reveal what Neanderthals ate from analysis of DNA in their teeth, and new CRISPR-Cas systems found in the genomes of uncultured microbes.

This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free – WITH FREE SHIPPING – by going to blueapron.com/twim

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

]]>55:28cleanTWiM #147: The Public Goods DilemmaFri, 10 Mar 2017 00:05:39 +0000The TWiM hosts reveal why phosphorus is essential for fungal brain disease, and how bacteria kill local competitors to favor the evolution of public goods cooperation.

This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free with your first purchase – WITH FREE SHIPPING – by going to blueapron.com/twim

This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free with your first purchase – WITH FREE SHIPPING – by going to blueapron.com/twim

]]>01:06:38cleanTWiM #146: Viral arbitriumThu, 23 Feb 2017 19:34:42 +0000Vincent, Elio and Michael discuss the finding of a prion in bacteria, and how communication between bacteria guides the decision between lysis and lysogeny.

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This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free – WITH FREE SHIPPING – by going to blueapron.com/twim

This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free – WITH FREE SHIPPING – by going to blueapron.com/twim

Links for this episode

This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free – WITH FREE SHIPPING – by going to blueapron.com/twim

This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free – WITH FREE SHIPPING – by going to blueapron.com/twim

]]>01:06:04cleanTWiM #143: E-scaffolds and receptor transferThu, 12 Jan 2017 21:19:12 +0000Vincent, Michael, and Michele explain the use of an electrochemical gradient to eliminate bacterial biofilms, and how phage susceptibility can be transferred by exchange of receptor proteins.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

]]>Vincent, Michael, and Michele explain the use of an electrochemical gradient to eliminate bacterial biofilms, and how phage susceptibility can be transferred by exchange of receptor proteins.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

]]>01:05:42cleanTWiM #142: A membrane-thickness caliperThu, 29 Dec 2016 19:08:25 +0000Vincent, Elio and Michele wind up a year of microbial podcasts with a story about the lack of resistance to a crop antifungal compound, and how a bacterium uses a molecular caliper to measure membrane thickness.

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Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

]]>Vincent, Elio and Michele wind up a year of microbial podcasts with a story about the lack of resistance to a crop antifungal compound, and how a bacterium uses a molecular caliper to measure membrane thickness.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

]]>58:37cleanTWiM #141: Nutritional immunity and polymicrobial infectionsThu, 15 Dec 2016 23:19:31 +0000Jennifer joins Vincent, Elio, and Michael to talk about the work of her laboratory on how a respiratory virus enhances bacterial growth by dysregulating nutritional immunity.

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This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

This show is sponsored by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. This Holiday season give someone a Drobo to keep all their files and memories safe forever

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

This show is sponsored by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. This Holiday season give someone a Drobo to keep all their files and memories safe forever

At the Hamilton, Montana Performing Arts Center, Vincent speaks with three local high school graduates and two high school teachers about how Rocky Mountain Laboratories influenced school science programs and opened up career opportunities.

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This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

At the Hamilton, Montana Performing Arts Center, Vincent speaks with three local high school graduates and two high school teachers about how Rocky Mountain Laboratories influenced school science programs and opened up career opportunities.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

]]>01:20:13cleanscience,school,high,viral,mountain,teaching,mt,career,hamilton,rocky,virus,viruses,microbe,microbiology,virology,laboratoriesTWiM #139: Frackibacter and sticky fingersFri, 18 Nov 2016 21:10:50 +0000The TWiM team discusses microbial DNA found on ATM machines in New York City, and how hydraulic fracturing, or fracking, alters microbial ecosystems deep in the Earth.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

]]>01:11:27cleanTWiM #138: Learning to love uranium and the A-baumThu, 03 Nov 2016 19:46:19 +0000The TWiM team brings you a bacterium from a Colorado field site that grows on uranium, and copper resistance in the emerging pathogen Acinetobacter baumannii.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

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]]>01:02:09cleanTWiM #137: The battle for oxygenThu, 20 Oct 2016 18:49:58 +0000Highlights of the Recent Advances in Microbial Control meeting in San Diego, and expansion of a gut pathogen by virulence factors that stimulate aerobic respiration.

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This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

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]]>01:08:54cleanTWiM #136: Diderms and then monodermsFri, 07 Oct 2016 06:03:09 +0000Them TWiM team discusses the importance of neutrophils in microbial infections, and evidence that ancient bacteria had two cell walls.

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This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

]]>01:06:41cleanTWiM #134: Lipids that live foreverThu, 08 Sep 2016 04:02:39 +0000Design of a synchronously lysing bacterium for delivery of anti-tumor molecules in mice, and hopanoids, the lipids that live forever, brought to you by the four Microbies of TWiM.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

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]]>01:04:23cleandelivery,bacteria,cargo,microbe,microbiology,synchronized,oncolytic,antitumor,lipid,lysis,cyanobacterium,hopanoid,hopane,nostocTWiM #133: Right under our nosesSat, 20 Aug 2016 08:49:49 +0000Insight into the biology of rhinovirus C from cryo-electron microscopy, and a novel antibiotic from a commensal bacterium that grows in the human nose, from the doctors of TWiM.

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This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

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This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

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This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

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Michael and Vincent present Spotlights, brief reviews of classic papers in the Journal of Bacteriology, and explain how a single bacterial species can reverse autism-like social deficits in the offspring of obese mice.

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Michael and Vincent present Spotlights, brief reviews of classic papers in the Journal of Bacteriology, and explain how a single bacterial species can reverse autism-like social deficits in the offspring of obese mice.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

]]>01:22:09cleanof,e,social,classic,plague,deficit,disorder,autism,journal,spotlight,obesity,calcium,protein,type,iii,oxytocin,bacteria,spectrum,coli,microbe,microbiology,seca,yersinia,pestis,synaptic,translocation,microbiome,yop,lactobacillus,secretion,bacteriologyTWiM #130: Interkingdom interactions at ASM MicrobeThu, 23 Jun 2016 22:53:41 +0000Filmed live in Boston, MA at Microbe 2016, David S. Schneider and Vanessa Sperandio talk about their work on regulation of bacterial virulence in the gut by bacterial adrenergic sensors, and the physiological mechanisms that make us ill and that help us recover.]]>Filmed live in Boston, MA at Microbe 2016, David S. Schneider and Vanessa Sperandio talk about their work on regulation of bacterial virulence in the gut by bacterial adrenergic sensors, and the physiological mechanisms that make us ill and that help us recover.]]>01:17:28cleanand,e,space,recovery,vampire,disease,resistance,bacteria,coli,microbe,microbiology,receptor,virulence,immunology,epinephrine,adrenalin,ehec,enterohemorrhagic,adrenergic,adhering,effacingTWiM #129: Dried and wrinkled, smooth and mucoidTue, 07 Jun 2016 00:22:00 +0000The arrival in the US of plasmid-mediated resistance to colistin antibiotics, a last line of defense against many gram-negative bacilli, and a quorum sensing system in a eukaryote are topics of this episode hosted by Vincent, Michael, and Michele.

Image: Etest used to determine the minimum inhibitory concentration of an antibiotic for a particular bacterium.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

]]>The arrival in the US of plasmid-mediated resistance to colistin antibiotics, a last line of defense against many gram-negative bacilli, and a quorum sensing system in a eukaryote are topics of this episode hosted by Vincent, Michael, and Michele.

Image: Etest used to determine the minimum inhibitory concentration of an antibiotic for a particular bacterium.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

]]>01:10:40cleancell,infection,wall,resistance,bacteria,fungus,tract,microbe,microbiology,quorum,sensing,superbug,antibiotic,urinary,cryptococcus,neoformans,peptide,mcr1,colistin,plasmidTWiM #128: A moonlighting phage proteinSat, 21 May 2016 04:03:52 +0000A eukaryote without a mitochondrion, and using a phage enzyme to eliminate intracellular bacteria are two topics discussed by the TWiMers on this episode.

Image (right): An entry in the ASM Agar Art Contest which bears an uncanny resemblance to one of the TWiM hosts.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completel free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completel free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

]]>01:17:35cleantherapy,bacteria,throat,microbe,microbiology,strep,bacteriophage,phage,streptococcus,eukaryote,mitochondrion,endolysin,pyogenesTWiM #127: Subway Snowblowers and Men in BlackThu, 05 May 2016 20:58:24 +0000The TWiM team explores microbes in snowblower vents on the ocean floor, and cleavage of antibody molecules by a Mycoplasma protease.

Image (right): Photograph of the ‘Subway’ snowblower vent on the sea floor at Axial Seamount, Juan de Fuca Ridge. Visible are white ‘snow’ in the vent and orange floc on the seafloor. Credit: Canadian Scientific Submersible Facility and the University of Washington

]]>The TWiM team explores microbes in snowblower vents on the ocean floor, and cleavage of antibody molecules by a Mycoplasma protease.

Image (right): Photograph of the ‘Subway’ snowblower vent on the sea floor at Axial Seamount, Juan de Fuca Ridge. Visible are white ‘snow’ in the vent and orange floc on the seafloor. Credit: Canadian Scientific Submersible Facility and the University of Washington

]]>54:27cleanfab,gene,eruption,bacteria,transfer,fc,immune,mib,vent,microbe,microbiology,horizontal,snowblower,evasion,mycoplasma,mip,protease,hydrothermal,snowblowers,epsilonproteobacteria,subseafloor,igiTWiM #126: I’m not scared of zebrafish and mice and bears (oh my!)Fri, 22 Apr 2016 03:36:33 +0000The microbiome of hibernating bears, and zebrafish as a model for bacterial sepsis feature in this animal-centric episode of TWiM hosted by Vincent, Michael, and Michele.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

]]>The microbiome of hibernating bears, and zebrafish as a model for bacterial sepsis feature in this animal-centric episode of TWiM hosted by Vincent, Michael, and Michele.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

]]>Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.

A deep sequencing study of commercially available probiotics, and design and synthesis of a minimal bacterial genome are the topics tackled by Vincent, Michael, and Michele on this episode of TWiM.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

]]>01:15:28cleanin,trade,engineering,bacteria,microbial,framework,economic,automated,genome,microbe,mage,microbiology,situ,microbiome,promoter,multiplex,mutagenesisTWiM #122: Mayonii, microRNAs and the microbiomeThu, 25 Feb 2016 20:45:40 +0000Vincent, Michele, and Michael reveal the discovery of a new species of the spirochaete that causes Lyme disease, and fecal microRNAs that shape the gut microbiome.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

]]>Vincent, Michele, and Michael reveal the discovery of a new species of the spirochaete that causes Lyme disease, and fecal microRNAs that shape the gut microbiome.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

From the ASM Biodefense and Emerging Diseases Research meeting, Vincent speaks with Rebekah and Wyndham about their work on Rift Valley Fever virus and other vector-borne pathogens, and the evolution and pathogenesis of Yersinia pestis, the agent of plague.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

From the ASM Biodefense and Emerging Diseases Research meeting, Vincent speaks with Rebekah and Wyndham about their work on Rift Valley Fever virus and other vector-borne pathogens, and the evolution and pathogenesis of Yersinia pestis, the agent of plague.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

]]>01:05:35nopack,cloud,hr,hunting,soil,drop,mushroom,atmosphere,spore,microbe,microbiology,amoeba,buller,microbiome,nematode,protist,eukaryote,appendix,precipitation,heterotrophic,bacteriovore,cryptodifflugia,operculata,basidiospore,basidium,basidiomycetes,hilarTWiM #117: Finding the comammoxThu, 17 Dec 2015 19:10:52 +0000The TWiM team marvels over the finding of a completely nitrifying Nitrospira, and horizontal gene transfer from Wolbachia into an animal genome.

]]>01:00:58cleancarbon,metabolism,candida,fatty,microbe,microbiology,interactions,acids,microbiome,pathogenesis,commensal,albicans,hostpathogen,mediumchain,msphereTWiM #115: Profiling the PoglianosFri, 20 Nov 2015 08:48:39 +0000Vincent visits the laboratories of Kit and Joseph Pogliano on the campus of the University of California, San Diego, where he learns about their work on the bacterial cytoskeleton, sporulation, and the effects of antibiotics on bacterial cells.

Visit microbeworld.org/twim for complete shownotes including the special video version of this episode. Thanks for listening and watching!

]]>Vincent visits the laboratories of Kit and Joseph Pogliano on the campus of the University of California, San Diego, where he learns about their work on the bacterial cytoskeleton, sporulation, and the effects of antibiotics on bacterial cells.

Visit microbeworld.org/twim for complete shownotes including the special video version of this episode. Thanks for listening and watching!

]]>56:23nobacteria,microbe,microbiology,profiling,antibiotic,bacteriophage,bacillus,subtilis,microscopy,cytoskeleton,sporulation,tubulin,morphology,cytological,spoqTWiM #114: Milestones in BlueFri, 06 Nov 2015 19:35:50 +0000Vincent, Elio, and Michele meet with Harry Mobley, Mary O’Riordan, and Vince Young at the University of Michigan, during the designation of the Department of Microbiology and Immunology as a Milestones in Microbiology site. They discuss how the laboratory has advanced the science and teaching of microbiology, and discuss faculty work on uropathogenic E. coli, induction of stress by bacterial infection, and the gut microbiome.

]]>Vincent, Elio, and Michele meet with Harry Mobley, Mary O’Riordan, and Vince Young at the University of Michigan, during the designation of the Department of Microbiology and Immunology as a Milestones in Microbiology site. They discuss how the laboratory has advanced the science and teaching of microbiology, and discuss faculty work on uropathogenic E. coli, induction of stress by bacterial infection, and the gut microbiome.

]]>01:11:00noTWiM #113: Waves of ChangeThu, 22 Oct 2015 21:42:35 +0000Vincent meets up with Romney and Duncan at the 79th annual meeting of the Southern California branch of the American Society for Microbiology, where they talk about emerging technologies for antimicrobial susceptibility testing, and next generation sequencing and advanced molecular diagnostics.

Visit microbeworld.org/twim to watch the video version and for complete shownotes including links mentioned.

]]>Vincent meets up with Romney and Duncan at the 79th annual meeting of the Southern California branch of the American Society for Microbiology, where they talk about emerging technologies for antimicrobial susceptibility testing, and next generation sequencing and advanced molecular diagnostics.

Visit microbeworld.org/twim to watch the video version and for complete shownotes including links mentioned.

]]>53:46noTWiM #112: Mushroom pickers and mushroom kickersSat, 26 Sep 2015 06:20:19 +0000The TWiM team wonders why definitions in biology often change, and discuss how the small molecule terrein is important for the growth of a soil fungus.

Links for this episode

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

]]>59:02noTWiM #110: Exploring unseen life with unpronounceable wordsWed, 19 Aug 2015 22:07:48 +0000The TWiM team focuses on the gut microbiome, from a single member, Akkermansia muciniphila, to the effect of antibiotics on its composition and colonization resistance against C. difficile.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Vincent and Michael speak with Katy Bosio about her research on pathogenesis, immunity, and vaccines against Franciscella tularensis, the causative agent of tularemia.

]]>

Vincent and Michael speak with Katy Bosio about her research on pathogenesis, immunity, and vaccines against Franciscella tularensis, the causative agent of tularemia.

]]>01:16:32noand,the,of,on,research,katy,agent,about,her,vaccines,immunity,pathogenesis,bosio,franciscella,tularensis,causative,tularemiaTWiM #105: Real bugs with legsFri, 05 Jun 2015 20:09:42 +0000The TWiM team reviews the microbiological safety of herbs in the United Kingdom, and how a peptide from the milkweek bug binds the ribosome and inhibits bacterial protein synthesis.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Image: Yellow colonies of S. aureus on a blood agar plate, note regions of clearing around colonies caused by lysis of red cells in the agar By: HansN. on wikimedia. From the study (Nat Gen) "...only a single naturally occurring nucleotide mutation was required and sufficient to convert a human-specific S. aureus strain into one that could infect rabbits."

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Image: Yellow colonies of S. aureus on a blood agar plate, note regions of clearing around colonies caused by lysis of red cells in the agar By: HansN. on wikimedia. From the study (Nat Gen) "...only a single naturally occurring nucleotide mutation was required and sufficient to convert a human-specific S. aureus strain into one that could infect rabbits."

Links for this episode:

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

The TWiM crew ponders the question of how a bacterium finds its middle when dividing, then divulge the transfer of interbacterial antagonism genes to eukaryotes, where they may function in innate defense.

The TWiM crew ponders the question of how a bacterium finds its middle when dividing, then divulge the transfer of interbacterial antagonism genes to eukaryotes, where they may function in innate defense.

]]>58:37nocell,disease,innate,type,gene,bacteria,mine,tae,transfer,vi,dae,division,tick,microbe,microbiology,immunity,lyme,horizontal,effector,secretion,borrelia,burgdorferi,amidase,peptidoglycanTWiM #97: There’s gold in them hillsWed, 04 Feb 2015 23:38:03 +0000The TWiM team reveal how bacteria in a shipworm’s gills help digest wood in the gut, and an approach that identifies a new antibiotic from the soil.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Links for this episode:

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

]]>01:08:06no3,vaccine,type,bacteria,parasite,microbe,microbiology,poliovirus,eradication,sabin,opv,microsporidian,salk,swarming,locust,ipvTWiM #91: Rats, viruses, and bacteriaFri, 14 Nov 2014 00:21:25 +0000Vincent, Elio, and Michele review a study of the viruses and bacteria in commensal rats in New York City.

Vincent meets up with Laurene and David at the Annual Meeting of the Southern California Branch of the American Society for Microbiology, where they discuss how the Los Angeles County Department of Health is preparing for an outbreak of Ebola virus infection, and Cepheid’s game-changing, modular PCR system for the diagnosis of infectious diseases.

]]>

Vincent meets up with Laurene and David at the Annual Meeting of the Southern California Branch of the American Society for Microbiology, where they discuss how the Los Angeles County Department of Health is preparing for an outbreak of Ebola virus infection, and Cepheid’s game-changing, modular PCR system for the diagnosis of infectious diseases.

]]>01:02:15nopublic,health,disease,bacteria,infectious,virus,tuberculosis,chain,reaction,mers,diagnosis,sars,microbe,microbiology,ebola,cepheid,polymerase,pcr,genexpertTWiM #89: Microbial handoffsWed, 15 Oct 2014 21:12:46 +0000Vincent, Michele, and Michael discuss how a gene from bacteria protects a tick from plant cyanide poisoning, and enhanced transmission of Streptococcus pneumoniae by influenza virus co-infection in mice.]]>Vincent, Michele, and Michael discuss how a gene from bacteria protects a tick from plant cyanide poisoning, and enhanced transmission of Streptococcus pneumoniae by influenza virus co-infection in mice.]]>01:13:14noinflammation,bacteria,hydrogen,influenza,pneumonia,tick,microbe,microbiology,cyanide,receptor,streptococcus,herbivore,tolllike,cysteine,neutrophil,synthetase,cyanogenic,polyphagousTWiM #88: A century of excellence in microbiologyWed, 01 Oct 2014 18:34:16 +0000Michele speaks with members of the Department of Bacteriology at the University of Wisconsin - Madison, on the occasion of its designation as a Milestones in Microbiology site, where they discuss how the department has advanced the science and teaching of microbiology.

]]>Michele speaks with members of the Department of Bacteriology at the University of Wisconsin - Madison, on the occasion of its designation as a Milestones in Microbiology site, where they discuss how the department has advanced the science and teaching of microbiology.
]]>50:26noscience,university,wisconsin,bacteria,madison,microbe,microbiology,milestones,bacteriologyTWiM #87: Avogadro, archaeal fossils, and ICAACWed, 17 Sep 2014 17:31:05 +0000Vincent, Elio, and Michael explore the fossilization of archaeal lipids, and highlight the recent ICAAC in Washington, D.C.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

]]>01:12:06cleanbehavior,eating,microbe,microbiology,microbiota,microbiome,aphid,endosymbiontTWiM #85: Oscillation in the ocean and a Verona integron Thu, 21 Aug 2014 03:28:18 +0000Vincent, Elio, Michael, and Michele discuss the diel transcriptional rythmns of bacterioplankton communities in the ocean, and extensively drug resistant Pseudomonas in Ohio.]]>Vincent, Elio, Michael, and Michele discuss the diel transcriptional rythmns of bacterioplankton communities in the ocean, and extensively drug resistant Pseudomonas in Ohio.]]>01:17:48notest,north,producer,pacific,primary,bacteria,field,repetitive,verona,sequence,typing,hodge,gyre,microbe,microbiology,photosynthesis,electrophoresis,encoded,pulsed,pcr,transcriptome,pseudomonas,carbapenem,integron,subtropical,prochlorococcus,pelagibacterTWiM #84: Microbiology Down UnderMon, 11 Aug 2014 17:27:40 +0000In Melbourne, Australia Vincent speaks with David, Melanie, and Adam about their work on group A Streptococcus, Helicobacter pylori, and infections of Koalas with Chlamydia.]]>In Melbourne, Australia Vincent speaks with David, Melanie, and Adam about their work on group A Streptococcus, Helicobacter pylori, and infections of Koalas with Chlamydia.]]>01:08:43novaccine,australia,koala,bacteria,microbes,queensland,microbiology,pylori,chlamydia,streptococcus,helicobacter,geelongTWiM #83: Illuminating tuberculosis and cryptococcosisThu, 24 Jul 2014 18:38:17 +0000Vincent, Michael, Elio and Michele review a new fluorogenic diagnostic test for tuberculosis bacteria, and the role of a metalloprotease in helping a fungus invade the central nervous system.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

]]>54:11noloss,bubonic,plague,biology,evolution,gene,synthetic,bacteria,transfer,valve,flea,microbe,microbiology,yersinia,pestis,biofilm,chromosome,saccharomyces,cerevisiae,pseudotuberculosis,proventricularTWiM #79: A community of microbiologistsThu, 29 May 2014 17:26:11 +0000Vincent, Michael, and Michele review highlights of the 2014 General Meeting of the American Society for Microbiology in Boston, MA.]]>Vincent, Michael, and Michele review highlights of the 2014 General Meeting of the American Society for Microbiology in Boston, MA.]]>01:11:32noroom,environment,climate,change,general,weight,meeting,airplane,gut,coral,bacteria,virus,influenza,built,microbe,microbiology,asm,contamination,microbiome,listeria,surfaces,bleaching,lectin,epistasis,ctype,holobiontTWiM #78: A bacterium grows in BrooklynThu, 15 May 2014 06:34:05 +0000Vincent, Elio, and Michael consider a fungal pathogen of insects that acquired a gene from its host that facilitates infection, and presence of gram-negative nosocomial pathogens on community surfaces near hospitals in Brooklyn. ]]>Vincent, Elio, and Michael consider a fungal pathogen of insects that acquired a gene from its host that facilitates infection, and presence of gram-negative nosocomial pathogens on community surfaces near hospitals in Brooklyn. ]]>01:03:57nohand,hygiene,community,infection,gene,bacteria,transfer,fungus,insect,microbe,microbiology,horizontal,acquired,citrobacter,enterobacteriaceae,metarhizium,robertsii,hgt,endophyte,entomopathogen,klebsiella,acinetobacter,betalactamase,cephalosporinresistantTWiM #77: Zombie plants and no pain, no gainThu, 01 May 2014 21:14:17 +0000Vincent, Elio, Michael, and Michelle review how a pathogen promotes plant attractiveness to insect vectors, and activation of sensory neurons that modulate pain and inflammation by bacterial infection.

]]>Vincent, Elio, Michael, and Michelle review how a pathogen promotes plant attractiveness to insect vectors, and activation of sensory neurons that modulate pain and inflammation by bacterial infection.
]]>01:08:21nodevelopment,sensory,bacteria,neuron,microbe,microbiology,capsaicin,arabidopsis,phytoplasma,leafhopper,immunomodulationTWiM #76: Genetic biopixels and a pathogenic sweet toothFri, 11 Apr 2014 22:26:40 +0000Vincent, Elio, Michael, and Michelle discuss the use of bacteria to build a genetic sensor for heavy metals, and how host sugars help enteric pathogens to expand after antibiotic treatment.

]]>Vincent, Elio, Michael, and Michelle discuss the use of bacteria to build a genetic sensor for heavy metals, and how host sugars help enteric pathogens to expand after antibiotic treatment.
]]>01:07:29nometal,genetic,bacteria,microbe,microbiology,antibiotic,sugars,pathogenic,enteric,biopixelsTWiM #75: Pellicles on pickle jarsThu, 27 Mar 2014 00:30:29 +0000Vincent, Elio, Michael, and Michelle discuss a symbiosis between a bacterium and fungus that increases the virulence of oral biofilms, and the assembly of amyloid fibers, which are needed for biofilm formation.

]]>Vincent, Elio, Michael, and Michelle discuss a symbiosis between a bacterium and fungus that increases the virulence of oral biofilms, and the assembly of amyloid fibers, which are needed for biofilm formation.
]]>01:21:51nodental,bacteria,fungus,candida,microbe,microbiology,symbiosis,amyloid,streptococcus,biofilm,bacillus,subtilis,caries,tapa,mutans,albicansTWiM #74: It came from the Siberian permafrostWed, 12 Mar 2014 17:47:45 +0000Vincent, Elio, and Michael discuss a huge 30,000 year old virus recovered from Siberia, and nested symbiosis facilitated by horizontal gene transfer from bacteria to insect.]]>Vincent, Elio, and Michael discuss a huge 30,000 year old virus recovered from Siberia, and nested symbiosis facilitated by horizontal gene transfer from bacteria to insect.]]>01:10:14noviral,gene,virus,transfer,siberia,microbe,permafrost,microbiology,virology,horizontal,symbiosis,mealybug,megavirus,pithovirus,tremblaya,moranellaTWiM #73: Eyeing root nodule developmentThu, 27 Feb 2014 22:34:15 +0000

Vincent, Michael, and Michele discuss how soil-dwelling bacteria induce the formation of root nodules on legumes via a protein called CYCLOPS.

]]>Vincent, Michael, and Michele discuss how soil-dwelling bacteria induce the formation of root nodules on legumes via a protein called CYCLOPS.
]]>01:19:38nocalcium,root,factor,signal,nitrogen,cyclops,microbe,microbiology,transcription,fixation,nodule,symbiosis,legume,rhizobium,transductionTWiM #72: The benefits of virulence Thu, 13 Feb 2014 01:14:00 +0000Vincent, Elio, Michael, and Michele review how microbial virulence can be increased as a consequence of community surveillance and adaptation to macrophages.

]]>Vincent, Elio, Michael, and Michele review how microbial virulence can be increased as a consequence of community surveillance and adaptation to macrophages.
]]>01:14:10noadaptation,crop,microbe,microbiology,ecoli,virulence,drosophila,macrophage,fruitfly,pseudomonas,quorumsensingTWiM #71: Colon cancer’s little shop of horrorsWed, 22 Jan 2014 20:25:00 +0000Vincent, Michael, and Michele explain how the gut microbiome modulates colon tumorigenesis, and regulation of intestinal macrophage function by the microbial metabolite butyrate.

]]>Vincent, Michael, and Michele explain how the gut microbiome modulates colon tumorigenesis, and regulation of intestinal macrophage function by the microbial metabolite butyrate.
]]>01:18:38norisk,cancer,inflammation,colon,tumor,microbe,microbiology,colorectal,inhibitor,microbiome,macrophage,butyrate,hdacTWiM #70: A paroxysmal coughWed, 18 Dec 2013 20:14:36 +0000Vincent, Elio, Michael, and Michele discuss evidence that the acellular pertussis vaccine fails to prevent infection and transmission in nonhuman primates, and the use of bacterial cytological profiling to identify pathways targeted by antibiotics.]]>Vincent, Elio, Michael, and Michele discuss evidence that the acellular pertussis vaccine fails to prevent infection and transmission in nonhuman primates, and the use of bacterial cytological profiling to identify pathways targeted by antibiotics.]]>01:13:12novaccine,infection,transmission,mechanism,microbe,microbiology,profiling,whooping,cough,antibiotic,baboon,paroxysmal,pertussis,bordetella,acellular,cytologicalTWiM #69: Bacterial DNA in the human genome Wed, 27 Nov 2013 21:31:00 +0000Vincent, Elio, Jo, and Michele review evidence for bacterial DNA integrated into the human genome, and control of the symbiont population in an insect midgut.

]]>Vincent, Elio, Jo, and Michele review evidence for bacterial DNA integrated into the human genome, and control of the symbiont population in an insect midgut.
]]>01:09:42nointegration,cancer,gene,transfer,lateral,dna,tumor,insect,microbe,microbiology,symbiont,midgutTWiM #68: The fungus among usThu, 14 Nov 2013 00:43:27 +0000Vincent, Elio, Michael, and Michele discuss the amazingly high level of intergenera gene exchange among haloarchaea in an Antarctic lake, and the diversity of fungi on residential surfaces and the human forehead. ]]>Vincent, Elio, Michael, and Michele discuss the amazingly high level of intergenera gene exchange among haloarchaea in an Antarctic lake, and the diversity of fungi on residential surfaces and the human forehead. ]]>01:11:23nolake,environment,deep,exchange,surface,gene,built,microbe,microbiology,fungi,residential,haloarchaeaTWiM #67: Black mushrooms and RNA thermosensors Wed, 30 Oct 2013 21:57:48 +0000Vincent, Elio, and Michael discuss how temperature triggers Neisseria menigitidis immune evasion, and protection of mice from ionizing radiation by feeding them black mushrooms.]]>Vincent, Elio, and Michael discuss how temperature triggers Neisseria menigitidis immune evasion, and protection of mice from ionizing radiation by feeding them black mushrooms.]]>01:15:30nomice,secondary,mushroom,radiation,immune,structure,rna,meningitis,evasion,melanin,complement,neisseria,meningitidis,thermosensor,ionizingTWiM #66: The shape of a containerThu, 17 Oct 2013 19:03:50 +0000Vincent, Elio, Michael, and Michele discuss the curious outer membrane vesicles of Neisseria meningitides, and sources of Clostridium difficile infection revealed by genome sequencing.

Links for this episode:

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

]]>51:11noacid,mice,obesity,amino,fatty,microbe,microbiology,microbiota,microbiome,metabolite,branchedTWiM #64: URI and UTI at ICAAC in Denver Wed, 18 Sep 2013 16:58:00 +0000Vincent and Michael recorded this episode at the 53rd ICAAC in Denver, where they spoke with James Gern and James Johnson about rhinoviruses and extra-intestinal pathogenic E. coli.

]]>Vincent and Michael recorded this episode at the 53rd ICAAC in Denver, where they spoke with James Gern and James Johnson about rhinoviruses and extra-intestinal pathogenic E. coli.
]]>01:18:00nocold,common,infection,resistance,asthma,coli,tract,respiratory,rhinovirus,antibiotic,urinary,escherichia,pathogenic,allergen,exacerbation,extraintestinal,expec,st131,pyelonephritis,fluoroquinolineTWiM #63: Superantigens, S. aureus, and the armpit microbiomeWed, 04 Sep 2013 23:53:19 +0000Vincent, Michael, and Michelle discuss how a Staphylococcus aureus superantigen is critical for pathogenesis in a rabbit model, and the relationship of body odor to the axilla microbiome.]]>Vincent, Michael, and Michelle discuss how a Staphylococcus aureus superantigen is critical for pathogenesis in a rabbit model, and the relationship of body odor to the axilla microbiome.]]>01:26:01nomodel,body,rabbit,odor,microbiome,pathogenesis,staphylococcus,aureus,superantigen,axillaTWiM #62: Breaking bad and protein chain mail Wed, 21 Aug 2013 14:34:30 +0000Vincent and Michael discuss how infection with influenza A virus disperses Streptococcus pneumoniae biofilms leading to disease, and an amazing protein chainmail in a viral capsid

]]>Vincent and Michael discuss how infection with influenza A virus disperses Streptococcus pneumoniae biofilms leading to disease, and an amazing protein chainmail in a viral capsid
]]>01:19:54noTWiM #61: The irony of probioticsWed, 07 Aug 2013 21:06:33 +0000Vincent, Elio, and Michele review how horizontal gene transfer from bacteria to an insect genome enables a tripartite nested mealybug symbiosis, and how probiotic bacteria work by competing for iron in the intestine.

]]>Vincent, Elio, and Michele review how horizontal gene transfer from bacteria to an insect genome enables a tripartite nested mealybug symbiosis, and how probiotic bacteria work by competing for iron in the intestine.
]]>59:38noiron,gene,bacteria,microbes,transfer,salmonella,insect,genome,microbiology,intestine,horizontal,symbiosis,probiotic,mealybug,tripartiteTWiM #60: Microbial electrochemistry and diversity-generating retroelementsWed, 24 Jul 2013 19:38:09 +0000Vincent, Elio, and Michael discuss how an error-prone reverse transcriptase produces enormous diversity in a Legionella protein, and using microbes to convert waste into bioelectricity and chemicals.

]]>Vincent, Elio, and Michael discuss how an error-prone reverse transcriptase produces enormous diversity in a Legionella protein, and using microbes to convert waste into bioelectricity and chemicals.
]]>01:11:29noprotein,microbes,microbial,chemicals,diversity,transcriptase,retroelement,legionella,electrochemical,bioelectricityTWiM #59: Are viruses part of our immune system?Wed, 10 Jul 2013 21:17:05 +0000Vincent and Michael discuss the finding that bacteriophage might be part of the mucosal antimicrobial defense system.]]>Vincent and Michael discuss the finding that bacteriophage might be part of the mucosal antimicrobial defense system.]]>01:24:55nosystem,defense,virus,sticky,antimicrobial,immunity,bacteriophage,mucusTWiM #58: The brain microbiome?Thu, 20 Jun 2013 00:58:47 +0000Vincent, Elio and Michael review how underground mycelial networks carry signals that warn neighboring plants of aphid attack, and the presence of bacteria in the human brain.

]]>Vincent, Elio and Michael discuss fungi that use pheromones to trap nematodes, and how genes obtained from marine bacteria help gut bacteria degrade algal carbohydrates.
]]>58:34noroom,marine,hospital,gut,trap,bacteria,microbes,genes,sense,copper,transplant,pheromones,microbiology,fungi,fecal,carbohydrates,nematodes,algalTWiM #56: Live at ASM in DenverFri, 24 May 2013 16:37:24 +0000Vincent, Elio and Michael recorded this episode before an audience at the 2013 General Meeting of the American Society for Microbiology in Denver, Colorado, where they spoke with Andrew, Ferric, Suzanne, and Michelle about their research on a phage system for evading innate immunity, retractions of research papers, bacterial infections of the eye, and cytoplasmic defenses against intracellular bacteria.

This episode was filmed live at ASM GM 2013 in Denver, CO. Visit www.microbeworld.org/asmlive to watch the full video archive of this episode as well as all the videos recorded during GM.

]]>Vincent, Elio and Michael recorded this episode before an audience at the 2013 General Meeting of the American Society for Microbiology in Denver, Colorado, where they spoke with Andrew, Ferric, Suzanne, and Michelle about their research on a phage system for evading innate immunity, retractions of research papers, bacterial infections of the eye, and cytoplasmic defenses against intracellular bacteria.

This episode was filmed live at ASM GM 2013 in Denver, CO. Visit www.microbeworld.org/asmlive to watch the full video archive of this episode as well as all the videos recorded during GM.

]]>01:42:04cleansystem,live,research,paper,infection,eye,innate,bacteria,gm,asm,bacterial,immunity,evade,phage,defenses,retraction,intracellular,cytoplasmicTWiM #55: In the copper roomWed, 24 Apr 2013 19:32:09 +0000Vincent, Elio and Michael discuss the finding that copper surfaces reduce microbial burden and hospital-acquired infections in the intensive care unit.]]>Vincent, Elio and Michael discuss the finding that copper surfaces reduce microbial burden and hospital-acquired infections in the intensive care unit.]]>01:25:00nohospital,care,burden,infection,surface,mrsa,bacteria,microbial,copper,intensive,aquiredTWiM #54: Dueling injectors and the microgenderomeWed, 10 Apr 2013 18:19:44 +0000Vincent, Elio, and Michael review how sex-dependent differences in the mouse microbiome regulate type I diabetes, and counterattack among bacteria.]]>Vincent, Elio, and Michael review how sex-dependent differences in the mouse microbiome regulate type I diabetes, and counterattack among bacteria.]]>01:12:36no1,sex,mouse,diabetes,type,bacteria,dependent,microbiomeTWiM #53: Live in ManchesterFri, 29 Mar 2013 18:02:55 +0000Vincent, Laura, David, Kalin and Paul get together at the Society for General Microbiology meeting in Manchester, England to talk about next-generation approaches to antimicrobial therapy.]]>Vincent, Laura, David, Kalin and Paul get together at the Society for General Microbiology meeting in Manchester, England to talk about next-generation approaches to antimicrobial therapy.]]>01:00:38nopaul,david,williams,live,society,general,harper,resistance,laura,microbiology,quorum,sensing,antibiotic,sgm,piddock,kalin,vetsigianTWiM #52: Clinical microbiology with Ellen Jo BaronMon, 11 Mar 2013 15:00:00 +0000Vincent and Michael meet up with Ellen Jo Baron to talk about working in a clinical microbiology laboratory.]]>Vincent and Michael meet up with Ellen Jo Baron to talk about working in a clinical microbiology laboratory.]]>01:00:27nolab,jo,stanford,baron,ellen,clinical,microbiology,resistant,carbapenem,enterobacteriaceaeTWiM #51: Cave science with Hazel BartonWed, 27 Feb 2013 16:08:36 +0000Vincent, Michael, and Elio meet up with Hazel Barton to talk about cave microbiology.

]]>Vincent, Michael, and Elio meet up with Hazel Barton to talk about cave microbiology.
]]>01:18:41noancient,resistance,bacteria,cave,barton,microbiology,hazel,antibiotic,microbiome,carbonate,extremophileTWiM #50: These things aren’t even bacteria!Wed, 30 Jan 2013 19:37:00 +0000Vincent, Michael, and Stanley review the scientific career of Carl Woese.

Vincent, Michael, and Elio meet up with Jonathan Dworkin to discuss how bacteria form spores and how they return to vegetative growth.

]]>Vincent, Michael, and Elio meet up with Jonathan Dworkin to discuss how bacteria form spores and how they return to vegetative growth.
]]>01:09:33nob,jonathan,growth,bacteria,subtilis,vegetative,spores,dworkin,sporulationTWiM #45: Secreted nucleic acids RIG a STINGWed, 21 Nov 2012 21:03:19 +0000Vincent, Michael, Elio review innate immune sensing of Listeria secreted bacterial nucleic acids, and how Wolbachia enhances egg production in Drosophila.]]>Vincent, Michael, Elio review innate immune sensing of Listeria secreted bacterial nucleic acids, and how Wolbachia enhances egg production in Drosophila.]]>01:11:53noinnate,egg,immune,mosquito,bacterial,acids,drosophila,wolbachia,nucleic,listeria,rigiTWiM #44: Phage interruptusWed, 24 Oct 2012 19:48:25 +0000Vincent, Michael, Elio discuss the role of prophage excision in exit of Listeria from the phagosome, and analysis of bacterial communities in saliva.]]>Vincent, Michael, Elio discuss the role of prophage excision in exit of Listeria from the phagosome, and analysis of bacterial communities in saliva.]]>01:06:08nocommunity,bacteria,saliva,listeria,excision,prophage,phagosomeTWiM #43: Bacterial caveolae and zapping acne with phagesWed, 10 Oct 2012 17:00:52 +0000Vincent, Michael, Elio review formation of caveolae in a bacterium, and the limited genetic diversity and broad killing activity of P. acnes bacteriophages.]]>Vincent, Michael, Elio review formation of caveolae in a bacterium, and the limited genetic diversity and broad killing activity of P. acnes bacteriophages.]]>01:19:46nogenetic,p,acne,limited,diversity,phage,bacteriophages,bacterium,caveolae,acnesTWiM #42: Staphylococcus, a three-star pathogenWed, 26 Sep 2012 14:09:00 +0000Vincent, Michael, Elio, and Joe review highlights of the 15th International Symposium on Staphylococci and Staphylococcal Infections (ISSSI) in Lyon, France.]]>Vincent, Michael, Elio, and Joe review highlights of the 15th International Symposium on Staphylococci and Staphylococcal Infections (ISSSI) in Lyon, France.]]>01:11:42nointernational,infections,15th,symposium,icaac,staphylococci,staphylococcalTWiM #41: ICAAC live in San FranciscoThu, 13 Sep 2012 17:44:52 +0000Vincent and Michael travel to San Francisco for the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), where they meet with Bill, John, and Victor to discuss tuberculosis, monitoring infectious disease outbreaks with online data, and outside-the-box approaches to antibacterial therapy.

]]>Vincent and Michael travel to San Francisco for the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), where they meet with Bill, John, and Victor to discuss tuberculosis, monitoring infectious disease outbreaks with online data, and outside-the-box approaches to antibacterial therapy.
]]>01:43:08cleantb,live,data,san,francisco,disease,2012,flu,therapy,infectious,tuberculosis,antibacterial,microbiology,outbreak,healthmap,icaacTWiM #40: A mecca for microbiologyWed, 29 Aug 2012 17:12:00 +0000

**MicrobeWorld app users, click the "e" symbol in the bottom right corner of this description to watch a bonus video version of this episode!**

Vincent and Stanley meet with Waclaw Szybalski and John Kirby at Cold Spring Harbor Laboratory on the occasion of its designation as a Milestones in Microbiology site. They reminisce about how the well known laboratory has advanced the science and teaching of microbiology, and discuss John’s work on the soil dwelling, predatory myxobacteria.

If you don't have the app, please visit www.microbeworld.org/app to get more information about downloading the app for your iOS or Android device.

This video is also available for free at www.microbeworld.org in the TWiM section, epsiode #40.

]]>**MicrobeWorld app users, click the "e" symbol in the bottom right corner of this description to watch a bonus video version of this episode!**

Vincent and Stanley meet with Waclaw Szybalski and John Kirby at Cold Spring Harbor Laboratory on the occasion of its designation as a Milestones in Microbiology site. They reminisce about how the well known laboratory has advanced the science and teaching of microbiology, and discuss John’s work on the soil dwelling, predatory myxobacteria.

If you don't have the app, please visit www.microbeworld.org/app to get more information about downloading the app for your iOS or Android device.

This video is also available for free at www.microbeworld.org in the TWiM section, epsiode #40.

Vincent, Michael, and Elio reviews chapters from Microbes and Evolution, a collection of short, personal essays by microbiologists.

]]>Vincent, Michael, and Elio reviews chapters from Microbes and Evolution, a collection of short, personal essays by microbiologists.
]]>01:15:30noevolution,darwin,microbes,microbiologyTWiM #38: The sound of whooping coughThu, 02 Aug 2012 00:36:16 +0000Vincent, Jo, Michael, and Elio review an outbreak of pertussis in Washington, and how culturing can reveal rare members of the soil biosphere.]]>Vincent, Jo, Michael, and Elio review an outbreak of pertussis in Washington, and how culturing can reveal rare members of the soil biosphere.]]>01:10:52nosoil,toxins,olympics,bacteria,rare,biosphere,whooping,cough,pertussis,unculturableTWiM #37: Microbial Jekyll and HydeWed, 18 Jul 2012 20:39:35 +0000Vincent, Jo, Michael, and Elio discuss two examples of dynamic microbial symbioses that switch between mutualistic and pathogenic states.]]>Vincent, Jo, Michael, and Elio discuss two examples of dynamic microbial symbioses that switch between mutualistic and pathogenic states.]]>01:17:43cleanchemistry,dynamic,states,bacteria,microbial,insects,worm,pathogen,symbioses,mutualistic,algal,phaeobacter,photorhabdusTWiM #36: Domesticating a pathogenWed, 04 Jul 2012 20:22:00 +0000Vincent, Michael, and Elio explore the origin of Mycoplasma pathogens of ruminants, and share their thoughts on the recent ASM General Meeting.

]]>01:08:50cleanbacteria,virus,algae,microbe,microbiology,phytoplankton,protist,ehux,emiliania,huxlyei,eukaryoteTWiM #33: Tuning the immune organWed, 16 May 2012 18:35:00 +0000Vincent, Michael, and Ivo review the requirement for segmented, filamentous bacteria for the induction of a specific type of helper T cell in the gut.

]]>01:15:09cleansystem,outer,protein,gut,microbial,coli,module,transport,salmonella,assembly,microbe,membrane,microbiology,tam,translocation,escherichia,enterotype,citrobacterTWiM #30: Unraveling melioidosis and insulin resistanceWed, 04 Apr 2012 19:09:11 +0000On episode #30 of the podcast, Vincent, Elio, and Michael review how a toxin from Burkholderia pseudomallei inhibits protein synthesis, and the role of the gut microbiome in modulating insulin resistance in mice lacking an innate immune sensor.]]>On episode #30 of the podcast, Vincent, Elio, and Michael review how a toxin from Burkholderia pseudomallei inhibits protein synthesis, and the role of the gut microbiome in modulating insulin resistance in mice lacking an innate immune sensor.]]>01:10:04cleanmice,innate,resistance,protein,gut,insulin,sensor,immune,toxin,microbiome,synthesis,burkholderia,melioidosis,pseudomalleiTWiM #29: Death and an iron-loaded spikeWed, 21 Mar 2012 16:55:35 +0000On episode #29 of the podcast, Vincent and Stanley review how a phage pierces the cell membrane with an iron-loaded spike, and two programmed cell death systems in E. coli.]]>On episode #29 of the podcast, Vincent and Stanley review how a phage pierces the cell membrane with an iron-loaded spike, and two programmed cell death systems in E. coli.]]>01:02:48cleandeath,e,spike,cell,iron,pierce,coli,loaded,membrane,phage,programmedTWiM #28: Not unorganized bags of enzymesWed, 07 Mar 2012 17:12:00 +0000Vincent, Michael, and Elio review how competition within a host drives virulence of Streptococcus pneumoniae, and the expanding universe of the bacterial cytoskeleton.]]>Vincent, Michael, and Elio review how competition within a host drives virulence of Streptococcus pneumoniae, and the expanding universe of the bacterial cytoskeleton.]]>01:17:13cleanhost,competition,bacterial,virulence,streptococcus,pneumoniae,enzymes,cytoskeletonTWiM #27: An inflamed gut is good for SalmonellaWed, 22 Feb 2012 18:00:00 +0000Vincent, Elio, and Michael review how inflammation allows Salmonella to compete with fermenting gut microbes, and a riboswitch in bacterial and Archeal species that is triggered by fluoride.]]>Vincent, Elio, and Michael review how inflammation allows Salmonella to compete with fermenting gut microbes, and a riboswitch in bacterial and Archeal species that is triggered by fluoride.]]>01:14:31cleangut,bacteria,microbes,flouride,salmonella,microbiology,inflamed,fermenting,riboswitchTWiM #26: Suum cuiqueWed, 08 Feb 2012 18:05:00 +0000Vincent, Elio, and Michael discuss the finding of Sutterella species in the gut of autistic children, and methods for cultivating oral bacteria. ]]>Vincent, Elio, and Michael discuss the finding of Sutterella species in the gut of autistic children, and methods for cultivating oral bacteria. ]]>01:15:05cleanautism,oral,gut,bacteria,endocrinology,microbiome,sutterella,coxiellaTWiM #25: Magnetotactic bacteria and totally drug resistant TBWed, 25 Jan 2012 16:22:00 +0000On episode #25 of the podcast, Vincent, Elio, and Michael review bacteria that use the earth’s magnetic field for navigation, and identification of totally drug resistant Mycobacterium tuberculosis.]]>On episode #25 of the podcast, Vincent, Elio, and Michael review bacteria that use the earth’s magnetic field for navigation, and identification of totally drug resistant Mycobacterium tuberculosis.]]>01:16:55cleantb,iran,earth,india,drug,bacteria,field,tuberculosis,navigation,totally,magnetic,mycobacterium,resistantTWiM #24: This year in microbiology Wed, 11 Jan 2012 17:30:00 +0000

]]>Vincent, Jo, Elio, and Michael explain how a swarming bacterium helps disperse a non-motile fungus, and bacterial antibiotic tolerance mediated by hydrogen sulfide and starvation responses.
]]>01:16:05cleantolerance,bacteria,hydrogen,response,fungus,starvation,antibiotic,sulfide,swarming,nonmotileTWiM #22: Microbiology 911Wed, 14 Dec 2011 18:22:27 +0000Vincent and Michael speak with Alfred Sacchetti, MD, Chief of Emergency Services at Our Lady of Lourdes Medical Center, about microbial infections encountered in the emergency room.]]>Vincent and Michael speak with Alfred Sacchetti, MD, Chief of Emergency Services at Our Lady of Lourdes Medical Center, about microbial infections encountered in the emergency room.]]>01:38:25cleanmedicine,emergency,alfred,sacchettiTWiM #21: Symbiotic margheritasWed, 30 Nov 2011 18:44:14 +0000Vincent and Elio discuss ancient symbiosis between Alphaproteobacteria and catenulid flatworms, and a toxin from Helicobacter pylori that engages the mitochondrial fission machinery to induce host cell death.]]>Vincent and Elio discuss ancient symbiosis between Alphaproteobacteria and catenulid flatworms, and a toxin from Helicobacter pylori that engages the mitochondrial fission machinery to induce host cell death.]]>01:08:29cleandeath,host,cell,ancient,vaca,pylori,toxin,symbiosis,helicobacter,alphaproteobacteria,catenulid,cytotoxin,flatworms,vacuolatingTWiM #20: Facebook for bacteriaWed, 16 Nov 2011 20:12:00 +0000On episode #20 of the podcastThis Week in Microbiology, Vincent, Michael, and Elio follow up on the outbreaks of E. coli in Germany and cholera in Haiti, then discuss genes that confer self-identity to Proteus mirabilis.]]>On episode #20 of the podcast This Week in Microbiology, Vincent, Michael, and Elio follow up on the outbreaks of E. coli in Germany and cholera in Haiti, then discuss genes that confer self-identity to Proteus mirabilis.]]>01:07:51cleangermany,e,nepal,expression,gene,identity,haiti,cholera,coli,sprouts,outbreak,proteus,swarm,o104h4,mirabilisTWiM #19: Your microbiome is what you eatWed, 02 Nov 2011 19:44:51 +0000Vincent, Michael, Elio, and Jo discuss the genome sequence of Y. pestis from victims of the Black Death, and the effect of diet on gut microbial enterotypes.]]>Vincent, Michael, Elio, and Jo discuss the genome sequence of Y. pestis from victims of the Black Death, and the effect of diet on gut microbial enterotypes.]]>59:19cleandeath,black,diet,gut,microbial,sequence,victims,genome,yersinia,pestis,enterotypesTWiM #18: Escherichia coli K-12, an emerging pathogen?Wed, 19 Oct 2011 19:42:31 +0000Vincent, Michael, Elio, and Stanley explain how to make the human intestinal commensal and benign laboratory bacterium Escherichia coli K-12 into an invasive organism, and the unearthing of century-old spores in New York City.]]>Vincent, Michael, Elio, and Stanley explain how to make the human intestinal commensal and benign laboratory bacterium Escherichia coli K-12 into an invasive organism, and the unearthing of century-old spores in New York City.]]>01:14:05cleannew,york,k12,human,laboratory,invasive,coli,ecoli,escherichia,commensal,intestinal,organism,spores,bacterium,benignTWiM #17: Debugging endosymbiosis Wed, 05 Oct 2011 17:38:55 +0000Vincent, Michael, and Elio focus on endosymbiosis: the rapid spread of Ricekttsia in whitefiles, and a metabolic patchwork in nested symbionts of mealybugs.

]]>Vincent, Michael, and Elio focus on endosymbiosis: the rapid spread of Ricekttsia in whitefiles, and a metabolic patchwork in nested symbionts of mealybugs.
]]>01:10:31cleanmetabolic,rapid,nested,spread,patchwork,endosymbiosis,ricekttsia,whiteflies,symbionts,mealybugTWiM #16: ICAAC LiveThu, 22 Sep 2011 00:19:45 +0000On episode #16 of the podcastThis Week in Microbiology, Vincent, Michael, Arturo, Stuart, and David converse about antimicrobial resistance and why most fungi do not cause disease at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).]]>On episode #16 of the podcast This Week in Microbiology, Vincent, Michael, Arturo, Stuart, and David converse about antimicrobial resistance and why most fungi do not cause disease at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).]]>01:29:14cleansoap,disease,resistance,fungus,antimicrobial,fungi,icaac,antibacterials,chytridTWiM #15: Microbial long distance relationshipsWed, 07 Sep 2011 16:51:05 +0000On episode #15 of the podcastThis Week in Microbiology, Vincent, Michael and Jo review the number of species on Earth, evidence that the 2010 Haitian cholera outbreak originated in Nepal, and how gut microbiota influence the immune response to influenza virus infection of the lung. ]]>On episode #15 of the podcast This Week in Microbiology, Vincent, Michael and Jo review the number of species on Earth, evidence that the 2010 Haitian cholera outbreak originated in Nepal, and how gut microbiota influence the immune response to influenza virus infection of the lung. ]]>58:58cleannumber,earth,nepal,infection,gut,species,influenza,response,cholera,2010,immune,lung,outbreak,haitian,microbiotaTWiM #14: Vomocytosis and microbial transistorsWed, 24 Aug 2011 15:17:00 +0000On episode #14 of the podcastThis Week in Microbiology, Stanley, Margaret, Michael and Elio review how the fungus Cryptococcus escapes from macrophages, and electrical conductivity in nanowires formed by the bacterium Geobacter.]]>On episode #14 of the podcast This Week in Microbiology, Stanley, Margaret, Michael and Elio review how the fungus Cryptococcus escapes from macrophages, and electrical conductivity in nanowires formed by the bacterium Geobacter.]]>01:07:48cleanelectrical,fungus,bacterium,cryptococcus,macrophage,conductivity,nanowires,geobacterTWiM #13: Probiotics and inflammasomes: Telling good bacteria from the bad Wed, 10 Aug 2011 18:13:25 +0000On episode #13 of the podcast This Week in Microbiology, Stanley, Jo, Michael and Elio discuss how colonic microbial ecology and risk for colitis are regulated by an inflammasome, and amelioration of intestinal inflammation in mice by delivery of a probiotic-derived soluble protein to the colon.]]>On episode #13 of the podcast This Week in Microbiology, Stanley, Jo, Michael and Elio discuss how colonic microbial ecology and risk for colitis are regulated by an inflammasome, and amelioration of intestinal inflammation in mice by delivery of a probiotic-derived soluble protein to the colon.]]>57:44cleanmice,risk,protein,inflammation,ecology,microbial,colonic,intestinal,amelioration,inflammasome,probioticTWiM #12: Photothermal nanoblades and genome engineeringWed, 27 Jul 2011 16:38:32 +0000Vincent, Margaret, Michael and Elio review the use of photothermal nanoblades to dissect the Burkholderia intracellular life cycle, and manipulation of chromosomes in vivo for genome-wide codon replacement in E. coli.]]>Vincent, Margaret, Michael and Elio review the use of photothermal nanoblades to dissect the Burkholderia intracellular life cycle, and manipulation of chromosomes in vivo for genome-wide codon replacement in E. coli.]]>01:15:23cleanengineering,genome,photothermal,nanobladesTWiM #11: Chickens, antibiotics, and asthmaWed, 13 Jul 2011 17:26:21 +0000Vincent, Margaret, Michael and Elio review the presence of extended spectrum beta-lactamase genes in chicken meat and in humans, and a beneficial effect of Helicobacter pylori colonization on the development of allergen-induced asthma.]]>Vincent, Margaret, Michael and Elio review the presence of extended spectrum beta-lactamase genes in chicken meat and in humans, and a beneficial effect of Helicobacter pylori colonization on the development of allergen-induced asthma.]]>01:12:40cleanfood,beta,chickens,antibiotics,genes,meat,spectrum,asthma,pylori,helicobacter,lactamaseTWiM #10: A symbiotic cloaking deviceWed, 29 Jun 2011 17:41:53 +0000On episode #10 of the podcast This Week in Microbiology, Vincent, Margaret, Elio, Michael and Dickson discuss the symbiosis between the Hawaiian bobtail squid and the luminous, gram-negative bacterium Vibrio fischeri.]]>On episode #10 of the podcast This Week in Microbiology, Vincent, Margaret, Elio, Michael and Dickson discuss the symbiosis between the Hawaiian bobtail squid and the luminous, gram-negative bacterium Vibrio fischeri.]]>01:08:07cleansquid,hawaiian,symbiosis,luminous,bobtail,bacterium,fischeri,gramnegative,vibrioTWiM #9: Bean sprouts and E. coli O104:H4Wed, 15 Jun 2011 15:46:24 +0000Vincent, Michael, and Cliff review the outbreak of bloody diarrhea and hemolytic uremic syndrome in Germany caused by Shiga toxin-producing Escherichia coli O104:H4.]]>Vincent, Michael, and Cliff review the outbreak of bloody diarrhea and hemolytic uremic syndrome in Germany caused by Shiga toxin-producing Escherichia coli O104:H4.]]>01:16:35cleangermany,bloody,syndrome,bean,sprouts,diarrhea,ecoli,toxin,hemolytic,o104h4,shingaTWiM # 8: Live in NOLAWed, 01 Jun 2011 16:21:18 +0000Vincent, Michael, and Stanley recorded TWiM #8 live at the 2011 ASM General Meeting in New Orleans, with guests Andreas Baümler, Nicole Dubilier, and Paul Rainey. They spoke about how pathogens benefit from disease, symbioses between chemosynthetic bacteria and marine invertebrates, and repetitive sequences in bacteria.]]>Vincent, Michael, and Stanley recorded TWiM #8 live at the 2011 ASM General Meeting in New Orleans, with guests Andreas Baümler, Nicole Dubilier, and Paul Rainey. They spoke about how pathogens benefit from disease, symbioses between chemosynthetic bacteria and marine invertebrates, and repetitive sequences in bacteria.]]>01:26:21cleanpaul,new,live,orleans,marine,general,benefit,rainey,disease,nicole,meeting,andreas,bacteria,repetitive,2011,asm,pathogens,sequences,invertebrates,baumler,dubilier,symbioses,chemosyntheticTWiM #7: Cycles of life and death, light and darkWed, 18 May 2011 16:28:00 +0000Vincent, Cliff, Elio, Margaret, and Michael discuss programmed cell death in E. coli, and the daily synthesis and degradation of enzymes needed for photosynthesis and nitrogen fixation by cyanobacteria.]]>Vincent, Cliff, Elio, Margaret, and Michael discuss programmed cell death in E. coli, and the daily synthesis and degradation of enzymes needed for photosynthesis and nitrogen fixation by cyanobacteria.]]>01:04:09cleandeath,cell,nitrogen,ecoli,fixation,degradation,photosynthesis,enzymes,cyanobacteria,synthesis,programmedTWiM #6: Antibacterial therapy with bacteriophage: Reality or fiction?Wed, 04 May 2011 15:35:00 +0000Vincent, Cliff, Michael and Elio review the use of bacteriophages to manage infections, and the presence of antibiotic resistance genes in the bacteriophage from urban sewage and river water.]]>Vincent, Cliff, Michael and Elio review the use of bacteriophages to manage infections, and the presence of antibiotic resistance genes in the bacteriophage from urban sewage and river water.]]>01:22:11cleanwater,river,resistance,genes,manage,presence,sewage,infections,bacteriophage,antiobioticTWiM #5: Mercury-methylating Desulfovibrio and antimicrobial nanoparticlesWed, 20 Apr 2011 21:30:00 +0000Vincent, Ron, Cliff, and Michael discuss the genome sequence of a mercury-methylating bacterium and the antimicrobial effects of nanoparticles.]]>Vincent, Ron, Cliff, and Michael discuss the genome sequence of a mercury-methylating bacterium and the antimicrobial effects of nanoparticles.]]>01:15:51cleanmercury,sequence,antimicrobial,genome,nanoparticles,methylating,bacteriumTWiM #4: Cantaloupes and Salmonella gastroenteritisWed, 06 Apr 2011 18:00:00 +0000Vincent, Cliff, Margaret, and Michael review foodborne bacterial illness in the context of outbreaks associated with cantaloupes and Lebanon bologna.]]>Vincent, Cliff, Margaret, and Michael review foodborne bacterial illness in the context of outbreaks associated with cantaloupes and Lebanon bologna.]]>01:14:45cleanillness,bologna,cantaloupe,salmonella,foodborne,gastroenteritisTWiM #3: Anthrax, genomics and the FBI inquiryWed, 23 Mar 2011 14:47:00 +0000Vincent, Jo, Cliff, and Ron explore the genome analysis done in support of the Amerithrax investigation, and an insecticidal enterotoxin-deficient mutant of Bacillus thurigiensis.]]>Vincent, Jo, Cliff, and Ron explore the genome analysis done in support of the Amerithrax investigation, and an insecticidal enterotoxin-deficient mutant of Bacillus thurigiensis.]]>01:00:27cleananalysis,mutant,investigation,forensic,genome,microbiology,bacterial,bacillus,insecticides,amerithrax,insecticidal,enterotoxindeficient,thurigiensisTWiM #2: The plague, microbial virulence and the gut microbiomeWed, 09 Mar 2011 18:30:00 +0000Vincent, Cliff, and Michael review a fatal laboratory acquired Yersinia pestis infection, and how gut bacteria control body weight and metabolic activity.]]>Vincent, Cliff, and Michael review a fatal laboratory acquired Yersinia pestis infection, and how gut bacteria control body weight and metabolic activity.]]>01:15:43cleanprofessor,guy,plague,genetics,chicago,infection,microbial,malcolm,molecular,yersinia,pestis,virulence,microbiome,casadabanTWiM #1: Neisseria LINEs upWed, 23 Feb 2011 17:30:00 +0000On episode #1 of the podcast This Week in Microbiology, Vincent, Cliff, Michael, and Stan discuss transfer of DNA from a human host to a bacterial pathogen, and the ability of dry copper to kill bacteria on contact.]]>On episode #1 of the podcast This Week in Microbiology, Vincent, Cliff, Michael, and Stan discuss transfer of DNA from a human host to a bacterial pathogen, and the ability of dry copper to kill bacteria on contact.]]>01:03:23cleanlong,contact,kill,bacteria,element,dry,copper,transfer,dna,microbiology,bacterial,pathogen,genomes,interspersed