We report on observations of the sky region around the unidentified TeV source (TeV J2032+4130) carried out with the Whipple Observatory 10 m atmospheric Cerenkov telescope for a total of 65.5 hr between 2003 and 2005. The standard two-dimensional analysis developed by the Whipple collaboration for a stand-alone telescope reveals an excess in th...

We report on observations of the sky region around the unidentified TeV source (TeV J2032+4130) carried out with the Whipple Observatory 10 m atmospheric Cerenkov telescope for a total of 65.5 hr between 2003 and 2005. The standard two-dimensional analysis developed by the Whipple collaboration for a stand-alone telescope reveals an excess in the field of view at a pretrial significance level of 6.1. The estimated integral flux for this source is about 8% of the Crab Nebula flux. The data are consistent with a point-like source. Here we present a detailed description of the standard two dimensional analysis technique used for the analysis of data taken with the Whipple Observatory 10 m telescope and the results for the TeV J2032+4130 campaign. We include a short discussion of the physical mechanisms that may be responsible for the observed emission, based on possible association with known astrophysical objects, in particular, Cygnus OB2. Minimize

Rapid advances have been made in the use of pharmacological analgesia and sedation for newborns requiring neonatal intensive care. Practical considerations for the use of systemic analgesics (opioids, non-steroidal anti-inflammatory agents, other drugs), local and topical anaesthetics, and sedative or anaesthetic agents (benzodiazepines, barbitu...

Rapid advances have been made in the use of pharmacological analgesia and sedation for newborns requiring neonatal intensive care. Practical considerations for the use of systemic analgesics (opioids, non-steroidal anti-inflammatory agents, other drugs), local and topical anaesthetics, and sedative or anaesthetic agents (benzodiazepines, barbiturates, other drugs) are summarised using an evidence-based medicine approach, while avoiding mention of the underlying basic physiology or pharmacology. These developments have inspired more humane approaches to neonatal intensive care. Despite these advances, little is known about the clinical effectiveness, immediate toxicity, effects on special patient populations, or long-term effects after neonatal exposure to analgesics or sedatives. The desired or adverse effects of drug combinations, interactions with non-pharmacological interventions or use for specific conditions also remain unknown. Despite the huge gaps in our knowledge, preliminary evidence for the use of neonatal analgesia and sedation is available, but must be combined with a clear definition of clinical goals, continuous physiological monitoring, evaluation of side effects or tolerance, and consideration of long-term clinical outcomes. Minimize

For centuries medical schools in Britain and elsewhere had a fairly static curriculum based on what might be called the 'three Rs' of medicine, and consequently had to make room for new subjects as the need arose in a fashion which was sometimes makeshift. However, Southampton University has only had a medical school for six years, and therefore...

For centuries medical schools in Britain and elsewhere had a fairly static curriculum based on what might be called the 'three Rs' of medicine, and consequently had to make room for new subjects as the need arose in a fashion which was sometimes makeshift. However, Southampton University has only had a medical school for six years, and therefore their course on medical ethics and legal medicine was carefully integrated into the curriculum after some preliminary experiments carried out by a subcommittee which is continually reviewing the situation. Medical ethics has now a definite place in the fourth year, preceded by an introduction to ethical problems encountered in medicine in the first year. Not only do members of the medical faculty participate in this teaching but also members of the faculties of law and the arts. Minimize