Verb - When somebody is slowing you down in a crisis because they are hurt, fat, old, or any combination of the three. Often somebody you don't know or like so you decide to save yourself by killing or ditching them so you can make your escape. Comes from the show The Walking Dead.

I was running from a starving rabid bear and Dave was slowing me down because he broke his leg so I had to Otis his ass and leave him.

The zombies where closing in and since I never liked Steve I decided to Otis him by shooting him in the leg and make my escape.