Adrian Peterson couldn't ask for a better matchup this weekend as the Vikings welcome the Chicago Bears and the NFL's worst rushing defense to town.

Peterson rushed for 100 yards on 26 carries in the two teams' first meeting in Week 2 and is a lock to surpass the 100-yard mark this weekend based on these numbers courtesy of Bears sideline reporter Zach Zaidman on Twitter:

The Bears are surrendering more than 145 yards per game on the ground and have already given up 14 rushing touchdowns in 11 games after allowing just six all of last season. That bodes extremely well for the league's second-leading rusher on Sunday afternoon.

On top of those eye-popping numbers, Peterson is coming off a season-high 146 rushing yards against the Green Bay Packers in Week 12.

Barring injury or a dramatic improvement from the Bears front seven, Peterson is set for a big-time performance this holiday weekend.

Staying in the NFC North, Detroit's Matthew Stafford looks poised for an impressive outing against the Green Bay Packers on Thanksgiving.

Not only have Stafford and his favorite target Calvin Johnson been lighting up the league all year long, but the Packers secondary has struggled immensely of late, ranking 26th in the NFL in fewest yards per attempt allowed.

What's more, Green Bay's defense has only recorded four interceptions in 11 games this season. Only Houston has been as bad in that category. For Stafford, who tossed four picks in Week 12's loss to Tampa Bay, the Packers' inability to force turnovers in the passing game will be key to allowing him to take more risks down the field.

Win or lose, Stafford and his biggest weapon, Johnson, who didn't suit up for the two teams' previous matchup in Week 5, are sure to turn in colossal performances.

Another fantasy superstar set for a big day on Thanksgiving is Dallas Cowboys wide receiver Dez Bryant, who will be up against a dismal Oakland Raiders secondary on Thursday.

Oakland ranks 25th against the pass this season and has surrendered 21 touchdowns through the air this season. Only six teams have allowed more. Keep in mind that Bryant ranks eighth in the NFL in receiving touchdowns through 12 weeks and will be catching passes from a touchdown machine in quarterback Tony Romo.