Medications for Viral Hepatitis

The information provided here is meant to give you a general idea about each of the medications listed below. Only the most general side effects are included, so ask your doctor if you need to take any special precautions. Use each of these medications as recommended by your doctor, or according to the instructions provided. If you have further questions about usage or side effects, talk to your doctor.

Medications may be given to treat
hepatitis B
or
C. The drugs have limited success and may produce side effects. More than one drug may be advised. Not all people are candidates for treatment with these medications. Discuss your treatment options with your doctor.

Prescription Medications

Alpha interferons

Telbivudine

Entecavir

Lamivudine

Adefovir

Ribavirin

Protease inhibitors

Telaprevir

Boceprevir

Simeprevir

Sofosbuvir

Alpha Interferons

Alpha interferon is injected, usually daily or three times per week. It is used to treat hepatitis B and C. These medications may be given individually or in combination. You may receive treatment for about four months or longer, but time varies. Alcohol must not be consumed during treatment with interferon.

Telbivudine
is available in liquid and tablet forms. It is appropriate for adolescents 16 years of age or older and adults with chronic hepatitis B. It is usually taken once daily. Optimal duration of therapy is unknown.

Protease inhibitors are used to treat hepatitis C. They interfere with viral reproduction in the body, slowing the growth of hepatitis C.
Protease inhibitors are taken in combination with other medications. It is important to remain adequately hydrated when taking them.

Possible side effects include:

Rash

Itching

Anemia

Nausea or vomiting

Fatigue

Problems with or loss of taste

Anal irritation (telaprevir)

Sensitivity to light (simeprevir)

When to Contact Your Doctor

If you develop any side effects to the medications

If any of your symptoms worsen

Special Considerations

If you are taking medications, follow these general guidelines:

Take your medication as directed. Do not change the amount or the schedule.

Do not stop taking them without talking to your doctor.

Do not share them.

Use a measuring spoon, cup, or syringe to give the right dose. Make sure it has the same measurements as the medication. For example, if the medication is given in milliliter (mL), the device should also say mL.

Know what the results and side effects. Report them to your doctor.

Some drugs can be dangerous when mixed. Talk to a doctor or pharmacist if you are taking more than one drug. This includes over the counter medication and herb or dietary supplements.

Plan ahead for refills so you do not run out.

Revision Information

This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.

What I need to know about Hepatitis B. National Digestive Diseases Information Clearinghouse website. Available at:
http://digestive.niddk.nih.gov/ddiseases/pubs/hepb%5Fez/index.aspx.
Updated December 19, 2012. Accessed February 14, 2014.