I primarily play Ranged AD, various Junglers, or solo top champions. Looking for which runes are the most universally useful/most cost effective to buy across many roles. These are the sets of runes I own.

3 Answers
3

First and foremost I'd get some scaling magic resist glyphs. The flat ones are great when you're mid, or you know you're going against a mage up top (e.g. vlad) but for blind pick or bottom lane or jungle I'd always go with scaling over flat.

Other than that, you have just about any runes you'd want to cover those roles.

I'd recommend picking up a mage page (flat AP quints, flat AP yellows, magic pen reds) and a support page (avarice quints and yellows, flat armor reds); being able to play a variety of roles is more important than being specialized at one IMO.

I found this image flow chart to be rather useful for getting up and running with runes. These are general idea runes and once you get to know some champs you may want to get something different but I feel like this is a good start.

For the most part I have the runes that this guide shows, XD I own around 25 champions or so (most AD, but I have at least two or three for each role) and have around 270 wins under my belt. This guide seems like it's for people that have just hit 20/30. So I guess I'm looking for the next step after this.
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ConfuzzledmaniacJul 12 '12 at 4:04

Ah okay. Well I guess the next step would be getting something more champ specific? I know I have some runes specifically for some champs.
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The JugJul 12 '12 at 14:45