The rock band U2's Vertigo Tour began in 2005 in support of their 2004 album How to Dismantle an Atomic Bomb.

The tour grossed $260 million in 90 sold-out concerts in 2005, making it the top-grossing tour of the year. In North America alone, the tour grossed $138.9 million The Vertigo Tour won the 2005 Billboard Roadwork Touring Awards for Top Tour, Top Draw, and Top Single Event.The tour's opening night was March 28, 2005 at the iPayOne Center in San Diego, California in the United States. The first leg took place in North American indoor arenas, the second leg in European outdoor stadiums during the summer, and the third leg back in North American arenas in the autumn. A fourth leg of outdoor stadium shows began in February 2006 in Mexico, and ran through March, visiting Brazil, Argentina, Chile; many of these locales had not seen a live U2 performance in nearly a decade. The last 10 planned dates from this leg, however, were cancelled as a result of a serious illness affecting an immediate family member of the band, and will reportedly be rescheduled.