Aim: A Comparative Study of Shankh Bhasma and Guduchi Satva in Urdhvag Amlapitta patients along with anupan koshn jala Objective: • To assess the efficacy of Shankh Bhasma in Urdhvag Amlapitta patients. • To assess the efficacy of Guduchi Satva in Urdhvag Amlapitta patients • To compare the efficacy of Shankha Bhasma and Guduchi Satva in • Urdhvag Amlapitta patients. • To assess the disease according to aetiological factors. • To assess the efficacy of drugs in view of symptoms of patient. • To assess any other associated benefits as well as side effects. Method: After complete examination and investigations, all the patients was randomly divided into two groups – I. Group A: In this group 30 patients was treated with Shankha Bhasma with Anupana Koshna Jala. II. Group B: In this group 30 patients was treated with Guduchi Satva with Anupana Koshna Jala. Assessment Criteria: For symptoms - subjective parameters was considered. For signs - Appropriate clinical parameters was considered. Grading & Scoring For Symptoms & Signs. Types of study Clinical Study Period of Study Total 30 days Follow Up – Both groups was examined time to time for expected results. 1st follow up - 10th Day 2nd follow up - 20thDay 3rd follow up - 30th Day Results: In Urdhvag Amlapitta the efficacy of treatment with Shankha Bhasma is equal to the efficacy of treatment with Guduchi satva as per statistical analysis. But percentage wise result of Guduchi Satva is better than Shankha Bhasma. Statistical Analysis: The Statistical Analysis reveals that In Urdhvag Amlapitta the efficacy of treatment with Shankha Bhasma is equal to the efficacy of treatment with Guduchi satva. But percentage wise result of Guduchi Satva is better than Shankha Bhasma. Conclusion: In Urdhvag Amlapitta the efficacy of treatment with Shankha Bhasma is equal to the efficacy of treatment with Guduchi satva. But percentage wise result of Guduchi Satva is better than Shankha Bhasma.