4. Sad Keanu

After a few years of lesser hits and the misjudged The Day the Earth Stood Still remake, Reeves exploded back into the cultural consciousness in 2010 thanks to a simple paparazzi picture of the poor guy pensively eating a sandwich. Out of that, the Sad Keanu meme was born, but to his credit, the actor has always good-naturedly rolled with it, maintaining that the viral reaction is all in good fun. But really, all the ironic meme-ification of Keanu did was remind us how much we missed the guy.