While the heroes are away fighting World War Hulk, the villains can play...M.O.D.O.K., sick of being hunted and hounded by A.I.M., gathers together an eclectic team of Marvel's Most Wanted to pull off one last, big score.

But news travels fast along the grapevine of villainy -- and pretty soon every bad guy in the Marvel Universe is gunning for the Big-Headed One's unspeakably powerful prize. Executing their heist may be the easy part, because getting away with their loot alive is going to be the real challenge for M.O.D.O.K.'s 11!