Dr. José Teixeira from Universidade do Porto in Portugal will talk about the hormetic role of redox-active polyphenols in human health and disease.

According to Dr Teixeira, polyphenols are well-known antioxidant molecules, which present different mechanisms at several subcellular compartments.- Polyphenols, in its oxidized quinone form, may act as potent regulators of the cellular redox status.- Mitochondria, the cell’s powerhouse, adapt to environmental factors by producing effectors that activate multiple pathways related to oxidative stress balance.- Targeting mitochondria with therapeutic agents is an effective therapeutic strategy in human health and disease.- Re-designing natural products and improving intracellular addressing can be a promising strategy to improve the cellular antioxidant status and contribute to decrease oxidative stress.