IFN-beta
msds (material safety sheet)

IFN-beta
Synthesis Reference

IFN-beta
Molecular Weight

IFN-beta
Melting Point

IFN-beta
H2O Solubility

IFN-beta
State

Liquid

IFN-beta
LogP

-0.447

IFN-beta
Dosage Forms

Solution (Subcutaneous Injection); Powder for solution

IFN-beta
Indication

For treatment of relapsing/remitting multiple sclerosis

IFN-beta
Pharmacology

Interferon beta upregulates the expression of MHC I proteins, allowing for increased presentation of peptides derived from viral antigens. This enhances the activation of CD8+ T cells that are the precursors for cytotoxic T lymphocytes (CTLs) and makes the macrophage a better target for CTL-mediated killing. Type I interferons also induce the synthesis of several key antiviral mediators including 2'-5' oligoadenylate synthetase (2'-5' A synthetase), beta-2 microglobulin, neopterin and protein kinase R.