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After a car and a truck smash into each other head on, Flack finds a dead girl in a barrel that came from the truck. Inside the truck, Danny and Lindsay find evidence that the driver, who fled the scene after the collision, was keeping someone prisoner in the back. The CSIs recover a container of urine and notice the door was locked from the cab side of the truck. Back at the morgue, Sid shows Mac that the girl in the barrel bled to death–after her liver was removed. Mac realizes she was the victim of an illegal organ trafficker and goes to find out who in the city with the same blood type as the girl–AB–is receiving a liver. Lindsay gets a match to prints found on the steering wheel of the truck: an ex-con named Casey Steele. Flack finds a man Steele carjacked in the hospital: Joseph Winston stopped to help Steele after the accident and Steele pulled a gun on him, shoved a terrified girl in his car and forced him to drive ten miles before shooting him and leaving him for dead, taking his car, cell phone and wallet. Lindsay gets a DNA hit on the girl from the back of Steele’s truck, identifying her as Madeline Briggs, a girl who went missing in Miami. She discovered a sedative in Madeline’s urine–and the pregnancy hormone. Adam has found evidence of multiple women being held in the back of Steele’s truck, many of whom are in the missing person’s database. Adam pulls up the pictures of the women and Lindsay recognizes the dead girl among them–Debbie Menzel from Atlanta. Stella interrupts to tell them that Ray Langston is on the video phone. Mac takes the call and Ray tells him about his time in Miami and his vow to Madeline’s mother that he’d find her. Mac invites him to New York, and Ray rushes to join him.

Ray arrives by helicopter and discusses the case with Mac, telling him that the Zeta gang is behind the abduction of young women ages 19-25, who are then used as sex slaves, surrogates and eventually organ donors. The two bond in front of the World War II memorial, both remembering their fathers. Hawkes tracks down a patient with type AB blood who was waiting for a liver who was removed from the organ donation waiting list the day before. Flack goes to the clinic where he’s being operated on and catches the doctor, Harvey Fuller, right before he goes into surgery on the man. After the surgery, Flack arrests him and brings him to the station where Fuller tells him and Hawkes that he would make a call to a number and leave a message saying what organ he needed and it would show up. Hawkes lays into him, accusing him of betraying his Hippocratic Oath as a doctor. Fuller insists he’s never seen Casey Steele before. The team gets a hit on Joseph Winston’s stolen phone and traces Steele to a local pharmacy. Flack and Hawkes race to the scene, but Steele escapes. The team finds the car he’s been using and Lindsay recovers soil from the brake pedal, which the team compares to reference samples and matches the soil to Corona Scrap Junkyard. Mac, Langston and Flack race to the junkyard and find Steele, whom they apprehend after a chase. Langston urges him to take a deal, but Steele refuses to give them any information. Langston calls Madeline’s mother to tell her the girl is still missing. Mac reassures Langston that he will find Madeline, who as they speak is in the back of a truck headed to Las Vegas…