This is typically due to a path issue with the method or data files. Are you saving the method with the data file? Does the method have a rtlock folder in it, and is so the data files in that folder, do they have an embedded method?

Let me know if you are still having issues. If so then does the simulate sequence work? If so when you run the sequence it creates a sequence_info.log in \masshunter\gcms\x\. If not then in the same folder you should see simulate_sequence.log. I would need to see these.

I just wanted to follow-up to see if this issue is resolved. If so, please come back to the post and click the “Correct Answer” button on the response that help so it will make the solution more visible. If you still need help, just let us know and we would be happy to continue working with you.