FHL3

FHL3

Official Full Name

four and a half LIM domains 3

Background

The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene.

FHL3 involved in several pathways and played different roles in them. We selected most pathways FHL3 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with FHL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name

Pathway Related Protein

FHL3 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by FHL3 itself. We selected most functions FHL3 had, and list some proteins which have the same functions with FHL3. You can find most of the proteins on our site.

FHL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FHL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of FHL3.