VIDEO: Canadian funding of $19.4 million will support 15 landmark projects to improve mental health diagnosis and care in developing countries: "the most neglected of neglected diseases. "
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Credit: Grand Challenges Canada

Grand Challenges Canada, which is funded by the Government of Canada, today announced a landmark $19.4 million in support of 15 innovative, pioneering projects designed to improve mental health diagnosis and care in developing countries, many of them nations ravaged by conflict and disaster as well as poverty. The projects were selected through competitive scientific peer review from among 97 ideas submitted in response to a Grand Challenge to propose innovations that increase access, improve treatment, and address stigma for people with mental health disorders in developing countries.

Globally close to 450 million people have mental health disorders; more than 75% of that number live in developing countries. And, according to the World Health Organization, 85% of developing world patients with serious mental disorders receive no treatment at all.

"Mental health disorders are a leading cause of suffering and disability everywhere, but the problem is especially acute in the developing world," said Dr. Peter A. Singer, CEO of Grand Challenges Canada. "There is very little funding for mental health innovations in low- and middle-income countries, where mental illness is the most neglected of many neglected diseases. It's a terrible denial of human potential."

"Canada has a long and proud tradition of fostering innovation to improve the lives of people living in some of the most desperate situations, " said the Honourable Jim Flaherty, Minister of Finance for Canada. "Global Mental Health is a significant challenge which, left unaddressed, could undermine the health, social and economic futures of developing countries."

15 projects in 14 low and middle income countries will test bold new ideas for addressing mental health issues, where patients are often severely stigmatized - even chained or locked up in the absence of understanding or care.

*Afghanistan has suffered through 30 years of conflict in the recent past. Over one million people have been killed; one million are disabled and millions of others are refugees. Most Afghan families have lost one or more family members during the conflict. As a result, it is estimated that about 50% of Afghanis over 15 years of age are suffering from mental health problems - depression, anxiety or post-traumatic stress disorder. Outside of Kabul, there is no mental health care system. The Grand Challenges Canada grant will help support improved awareness of mental health problems in rural areas through simple technologies such as text messages and information technology, including web-based tools, and teleconferencing to enable community health practitioners to reach patients in need, especially young people.

*Haiti, the poorest country in the Western Hemisphere, was traumatized by the 2010 earthquake that killed as many as 316,000 people, injured 300,000 and left 1.6 million homeless. Almost every person in this small country was affected. Later that same year, there was more misery when a cholera outbreak struck. As a result, it is estimated there is a high prevalence of mental health conditions in Haiti, yet mental health services are limited and of poor quality. With the support of Grand Challenges Canada, local health care organization Zanmi Lasante will increase treatment and care to Haitians through developing and testing culturally appropriate initiatives for community health workers to implement.

*Ethiopia. Der biaber anbessa yaser is an Amharic saying meaning, "Together a spider web will tie a lion." Dr. Clare Pain of Toronto and Dr. Dawit Wondimagegn of Ethiopia are leading the Biaber project which is planning to help tame the lion of mental illness in Ethiopia. A major cause of mental health disorders is domestic violence, which occurs in 72% of rural Ethiopian families, according to a recent study. The violence leads to depression, anxiety and suicide; furthermore, those who suffer are often severely stigmatized. This project will test improved screening and make treatments available to many who previously could not access care.

*Nigeria. As many as 25% of patients seen in local health centers suffer significant depression symptoms yet few are diagnosed and only about one in six of those diagnosed get treatment of any kind - lower than the African average of 30%. Depression has a major impact on productivity and mortality and compounds other health problems. Researchers will test low-cost innovations to improve recognition and diagnosis of the problem, improve patient adherence to treatment, and make interventions for depression more available and accessible with decentralized mental health services.

"Canada is to be congratulated for its bold new initiative to improve global mental health," said Dr. Shekhar Saxena, Director of the Department of Mental Health and Substance Abuse at the World Health Organization. "This area of health often remains ignored in health planning and resource allocation; for example, most low-income countries currently spend less than 25 US cents per person on mental health. Grand Challenges Canada is now making one of the largest ever investments in mental health innovations in the developing world, so WHO is very pleased indeed to support the initiative and help to ensure the most effective utilization of these vital investments."

"These bold ideas will bring hope to so many who suffer from mental disorders in the developing world," said Dr. Pamela Kanellis, Program Officer for Grand Challenges Canada. "Each of the projects underscores the importance of innovation to making mental health care available in low- and middle-income countries which are so desperately underserved and where stigma can result in people being locked up, even kept in chains, not receiving the care that they need. These projects will have a significant impact on the mental well-being of individuals, their families and their communities."

"Grand Challenges Canada is taking a global leadership position by funding innovation to address mental health disorders in the developing world. The $19.4 million we are putting into these projects is the largest single investment in global mental health innovation for this sadly under-resourced area of health." said Dr. Abdallah S. Daar, Chief Science and Ethics Officer at Grand Challenges Canada and co-leader of a defining study "Grand Challenges in Global Mental Health" published in Nature in 2011.

Projects will be conducted in the following countries (some are in more than one country):

Grand Challenges Canada is dedicated to supporting bold ideas with big impact in global health. We are funded by the Government of Canada through the Development Innovation Fund announced in the 2008 Federal Budget. We fund innovators in low and middle income countries and Canada. Grand Challenges Canada works with the International Development Research Centre (IDRC), the Canadian Institutes of Health Research (CIHR) and other global health foundations and organizations to find sustainable long-term solutions through integrated innovation - bold ideas which integrate science, technology, social and business innovation. Grand Challenges Canada is hosted at the Sandra Rotman Centre.

The International Development Research Centre (IDRC) supports research in developing countries to promote growth and development. IDRC also encourages sharing this knowledge with policymakers, other researchers and communities around the world. The result is innovative, lasting local solutions that aim to bring choice and change to those who need it most.

As the Government of Canada's lead on the Development Innovation Fund, IDRC draws on decades of experience managing publicly funded research projects to administer the Development Innovation Fund. IDRC also ensures that developing country researchers and concerns are front and centre in this exciting new initiative.

The Canadian Institutes of Health Research (CIHR) is the Government of Canada's health research investment agency. CIHR's mission is to create new scientific knowledge and to enable its translation into improved health, more effective health services and products, and a strengthened Canadian health care system. Composed of 13 Institutes, CIHR provides leadership and support to more than 14,100 health researchers and trainees across Canada.

CIHR is responsible for the administration of international peer review, according to international standards of excellence. The results of CIHR-led peer reviews will guide the awarding of grants by Grand Challenges Canada from the Development Innovation Fund.

The Sandra Rotman Centre is based at University Health Network and University of Toronto. We develop innovative global health solutions and help bring them to scale where they are most urgently needed. The Sandra Rotman Centre hosts Grand Challenges Canada.

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