In the spring of 1910 the Anderson Chamber of Commerce inaugurated a subscription campaign to raise money to build a college for young women in Anderson. The school’s supporters intended for the college to be affiliated with a church. In late November 1910, the South Carolina Baptist Convention met in Laurens and agreed to use the money and land to create a Baptist college. The first session opened in September 1912 with a student body of 115 young women. The Anderson College Historic District consists of a largely intact collection of five academic buildings and one landscape feature, the grounds, historically associated with the college. In addition to oak trees, the grounds include a number of mature magnolias, dogwoods, and evergreens that add to the park-like setting. A sidewalk extends through the lawn from Boulevard to the Merritt Administration Building, emphasizing its importance historically as the central structure or focal point of the campus and surrounding area. The original section of Anderson College, built between 1912 and 1920, contains four buildings, two loggias and a connector. In addition, the lodge (built ca. 1915-1920) is located at the main entrance near the Boulevard. The Neo-Classical style of architecture is consistent with each building, but every structure has individual qualities that add to their unique character. Listed in the National Register May 20, 1998.

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