The Regional Clinical Dental Research Center (RCDRC) welcomes the private sector with its products that need testing and refining.

STUDIES FUNDED BY COMMERCIAL AGENCIES

Support is provided by the RCDRC
for Industry interested in testing their oral products. Several clinical
research projects have been conducted for sponsors who successfully
obtained clearance from the Food and Drug Administration (FDA) for their
products.

The Center has state of the art clinic facilities dedicated to clinical
research. This includes 7 clinic operatories, a dedicated room for
physical examination, a waiting room area, an imaging center for
standardized oral radiographs, a biomedical laboratory, and a
bio-behavioral laboratory.

In addition, there is a core staff of dental hygienists, and dental assistants
who are especially trained to support researchers in clinical research.
The RCDRC currently has two study coordinators and can hire and support additional study coordinators if necessary. The
Center has dedicated working space for study coordinators.

Biostatistical support is available and provided by the Core
Bio-statistician. You can also receive advice in designing a study that would
be appropriate for your needs. Experienced clinical investigators will help
you. The RCDRC faculty and staff members have extensive experiences in
conducting clinical trials and being a partner with other centers in
multi-center clinical trials for the purpose of obtaining FDA clearance
(approvals).

The RCDRC Bio-medical laboratory and faculty can provide support
for designing and conducting studies involving
Microbiology (both aerobic and anaerobic processing)
Immunology (ELISAs and other assays), including studies of cytokines and other
markers of inflammation, and studies involving saliva samples.

The Clinical and Administrative Core provides clinical support and can
facilitate studies requiring expertise in all fields of Dentistry. The RCDRC
can facilitate collaboration with the Medical Research Centers.
The RCDRC clinic is equipped to manage subtraction radiography methods.

All research projects to be conducted at the RCDRC will undergo a peer review
process and approval must be obtained before a study can be started. This
process has been very helpful and has ensured a high standard of research at
the center. The process is expedient.

Expenses including costs for personnel, and supplies must be covered by grant
funding. Funding for commercial research projects must be obtained via Grants
and Contracts Services at the University of Washington.

A 24 month double blind randomized placebo controlled study to determine the effectiveness of MK-0217 in reducing alveolar bone loss in men and woman with moderate to severe periodontal disease in the absence of scaling and root planing