If the requirement of flag-transitivity is relaxed to one of vertex-transitivity, while the condition that the tiling is edge-to-edge is kept, there are eight additional tilings possible, known as Archimedean, uniform or semiregular tilings. Note that there are two mirror image (enantiomorphic or chiral) forms of 34.6 (snub hexagonal) tiling, both of which are shown in the following table. All other regular and semiregular tilings are achiral.

Grünbaum and Shephard distinguish the description of these tilings as Archimedean as referring only to the local property of the arrangement of tiles around each vertex being the same, and that as uniform as referring to the global property of vertex-transitivity. Though these yield the same set of tilings in the plane, in other spaces there are Archimedean tilings which are not uniform.

For edge-to-edge Euclidean tilings, the internal angles of the polygons meeting at a vertex must add to 360 degrees. A regular -gon has internal angle degrees. There are seventeen combinations of regular polygons whose internal angles add up to 360 degrees, each being referred to as a species of vertex; in four cases there are two distinct cyclic orders of the polygons, yielding twenty-one types of vertex. Only eleven of these can occur in a uniform tiling of regular polygons. In particular, if three polygons meet at a vertex and one has an odd number of sides, the other two polygons must be the same. If they are not, they would have to alternate around the first polygon, which is impossible if its number of sides is odd.

3.42.6 - does not generate a uniform tiling; can generate a 2-uniform tiling when used with either of the vertex types 3.4.6.4 or 3.6.3.6. In the later case, there are two inequivalent 2-uniform tilings that can be generated. (One of these later two are shown below).

Any number of non-uniform (sometimes called demiregular) edge-to-edge tilings by regular polygons may be drawn. Here are four examples:

32.62 and 36

32.62 and 3.6.3.6

32.4.12 and 36

3.42.6 and 3.6.3.6

Such periodic tilings may be classified by the number of orbits of vertices, edges and tiles. If there are orbits of vertices, a tiling is known as -uniform or -isogonal; if there are orbits of tiles, as -isohedral; if there are orbits of edges, as -isotoxal. The examples above are four of the twenty 2-uniform tilings. Chavey (1989) lists all those edge-to-edge tilings by regular polygons which are at most 3-uniform, 3-isohedral or 3-isotoxal.

Regular polygons can also form plane tilings that are not edge-to-edge. Such tilings may also be known as uniform if they are vertex-transitive; there are eight families of such uniform tilings, each family having a real-valued parameter determining the overlap between sides of adjacent tiles or the ratio between the edge lengths of different tiles.

These tessellations are also related to regular and semiregular polyhedra and tessellations of the hyperbolic plane. Semiregular polyhedra are made from regular polygon faces, but their angles at a point add to less than 360 degrees. Regular polygons in hyperbolic geometry have angles smaller than they do in the plane. In both these cases, that the arrangement of polygons is the same at each vertex does not mean that the polyhedron or tiling is vertex-transitive.