P3M Team in INT.
The main aim of our lab is to carry out world class research in fundamental neurosciences, from cellular to cognitive levels and to bridge gaps between fundamental and clinical approaches.
Our Team P3M investigates the plasticity of rhythmic motor networks (locomotion and breathing) during both development and pathological conditions (spinal cord injury, perinatal hypoxia/ischemia). Our studies scope from rodents (rats and transgenic mice) to transfer in humans (patents, RCTs, consulting activities in CROs…).

Field of interests.
My work has been devoted to study the cortical and spinal plasticity in relation to 1) altered sensorimotor experience during development and in adulthood, 2) perceptive abilities, and 3) stroke and perinatal hypoxia/ischemia. Using computational tools, I also studied neural coding. My current efforts are focused to develop animal models of disorders, such as Encephalopathy of Prematurity, spasticity, Cerebral Palsy and Developmental Coordination Disorder (DCD). Our rat models are based on mild intrauterine hypoperfusion (prenatal ischemia) and/or postnatal movement restriction. Our aim is to better understand the mechanisms underlying these invalidating disorders with no satisfying cure so far and to develop new strategies of neuroprotection/prevention, remediation and early diagnosis in high-risk pregnant women. My technical expertise mainly covers cognition, behaviors, learning, locomotion and in vivo/vitro electrophysiology, ranging from intracellular patch-clamp to extracellular multi-electrode recordings.