Medicine Overview of Lokcid Capsule

Uses of Lokcid Capsule

Side effects of Lokcid Capsule

Common

Nausea, Abdominal pain, Constipation, Flatulence, Diarrhoea.

How to use Lokcid Capsule

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It can be taken with or without food, but it is better to take Lokcid 20mg Capsule at a fixed time.

How Lokcid Capsule works

Lokcid 20mg capsule is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid-related indigestion and heartburn.

In Depth Information on Lokcid Capsule

Expert advice for Lokcid Capsule

Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.

Lokcid can decrease magnesium levels in blood. Get your magnesium levels checked regularly. You may need a magnesium supplement or need to discontinue your medicine.

Inform your doctor if you are suffering from osteoporosis as Lokcid can weaken your bones by decreasing calcium levels in blood. You may need a calcium supplement, preferably calcium citrate.

Lokcid is a well-tolerated medicine and provides relief for a long time.

It may take a few days to show its effect. You can take an antacid for a quick relief during this time unless your doctor has asked you not to use them.

Once you start feeling better, do not stop taking your medicine. Take it for the duration as advised by your doctor

Warnings

Special precautions for Lokcid 20mg Capsule

Alcohol

CAUTION

Taking a large amount of alcohol can increase acidity and ca

use acid reflux in the food pipe causing heartburn. This would decrease the effect of this drug and can aggravate your underlying condition.

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Pregnancy

WEIGH RISKS VS BENEFITS

Lokcid 20mg Capsule may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

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Lactation

Lokcid 20mg Capsule is probably safe to use during lactation

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Limited human data suggests that the drug does not represent a significant risk to the baby.

If you miss a dose of Omeprazole, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

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Patient Concerns

Frequently asked questions for Lokcid 20mg Capsule

Frequently asked questions for Omeprazole

Q. Can I take Lokcid with domperidone?

Lokcid can be safely taken with domperidone as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone works by increasing the gut motility and Rabeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.

Use of Lokcid is contraindicated if you are allergic to this medicine or any other medicine belonging to the same class of drugs. Also, do not take Lokcid if you are already taking a medicine containing nelfinavir (used for the treatment of HIV infection).

If you miss a dose of Lokcid, take it as soon as you remember and the next dose as scheduled. However, if it is almost the time for your next dose, skip the missed dose and take your next dose and then follow the regular schedule. Do not take double the dose.

Lokcid belongs to the group of medicines known as proton pump inhibitors (PPIs). This drug decreases the acid production in your stomach and is indicated for the treatment of conditions caused by excess acid secretion in the stomach.

Q. Is Lokcid better than pantoprazole?

Lokcid and pantoprazole both belong to the same class of drugs and are used in disease conditions with excess acid production like heartburn, acidity, stomach ulcers and intestinal ulcers. Both work by decreasing acid production in the stomach and are seen to be almost equally effective and safe in many clinical research studies. However, the response may vary from patient to patient and depend on the dose.

Lokcid has been reported to cause subacute cutaneous lupus erythematosus in many studies. Common signs and symptoms of this disease include painful joints, tiredness, weakness, rash, fever, anemia, mouth ulcers, hair loss, and many others and these may get aggravated again and again. Talk to your doctor if you experience these side effects as you may need to discontinue this medicine.

Q. Is Lokcid better than lansoprazole?

Lokcid and lansoprazole are two different medicines belonging to the same class 'proton pump inhibitors'. Some studies mention that lansoprazole is more effective than Lokcid for rapid relief of symptomatic heartburn. However, the effect of these medicines may vary upon individual response.

Q. Is Lokcid better than probiotics?

Probiotics and Lokcid perform different functions in the body. Lokcid suppresses acid production in the stomach to prevent injury to the walls of the stomach and esophagus while probiotics help to prevent the overgrowth of harmful bacteria in the body, help to maintain a balance in the stomach between good and harmful bacteria and protect the stomach from infections. Probiotics and Lokcid both are useful in the eradication of helicobacter pylori, which can cause stomach ulcers and also contribute to acid reflux.

Q. Can I take Lokcid with ondansetron?

Ondansetron is an anti-emetic medicine which helps in relieving nausea (feeling sick) or vomiting. No harmful effects have been seen when Lokcid is used with ondansetron. So, these two medicines can be taken together.

Lactose intolerance has been reported with the use of Lokcid in some patients. Many Lokcid preparations contain lactose as an ingredient. This is a digestive problem in which the patient cannot digest lactose, a type of sugar mainly found in milk and dairy products. The patient may complain of symptoms like flatulence (gas), diarrhea, bloating, stomach pain and feeling of being sick (nausea). Read the ingredients mentioned on the pack before taking the medicine.

Lokcid can be taken with vitamin E. The combinations seems to have a beneficial effect in terms of better maintenance of moderate to severe esophagitis. However, there are not many studies or reports on this subject. Talk to your doctor for more information on this.

Q. Can I take Lokcid with levosulpiride?

Lokcid can be safely taken with levosulpiride as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Levosulpiride works by increasing the gut motility and Lokcid decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.

Q. Is Lokcid better than famotidine?

Lokcid is a proton pump inhibitor (PPI) and famotidine is an H2 blocker. Both lowers the amount of acid in your stomach, treats heartburn, and heals ulcers. Studies have shown that Lokcid is more effective than famotidine for the control of gastro-oesophageal reflux disease symptoms, in rapid healing of duodenal ulcers and achieving more rapid pain relief. However, the effect of these medicines may vary upon individual response.

Use of proton pump inhibitors (PPIs) like Lokcid may be associated with an increased risk of Clostridium difficile–associated diarrhea (CDAD) as reported in few studies and informed by the US FDA as well. A possibility of CDAD can be there in patients taking PPIs and developed diarrhea that does not improve.

Lokcid can be taken by cancer patients as prescribed by a doctor. Since cancer patients may also take many other medicines for the primary cancer treatment or for other symptoms and infections, there are chances of drug interactions with Lokcid.

Lokcid can cause osteoporosis (thinning of bones) as it decreases the calcium absorption leading to calcium deficiency. This leads to an increased risk of bone fractures on long-term use, like hip, wrist or spine fractures. Inform your doctor if you have osteoporosis or if you are taking corticosteroids (these can increase the risk of osteoporosis) before starting your therapy. Take enough calcium and vitamin D to reduce the risk.

Proton (acid) pumps are found on the stomach mucosa and they are responsible for secreting acid in the stomach. Lokcid works by blocking this gastric acid pump and this unique mechanism of action helps in decreasing the acid secretion in the stomach.

Lokcid can rarely cause hepatitis with or without jaundice and very rarely it can lead to hepatic failure and encephalopathy in patients with the underlying liver disease. Lokcid does not cause hepatitis B or any other viral hepatitis. However, there are studies showing an increased occurrence of hepatic encephalopathy in hepatitis B patients using PPIs. These medicines should be used with caution in patients with the underlying liver disease.

Q. Is Lokcid better than dexlansoprazole?

Lokcid and dexlansoprazole are two different medicines belonging to the same class of proton pump inhibitors. There are no studies which compare Lokcid and dexlansoprazole. Lokcid and dexlansoprazole have similar action, but their effect may vary in different patients.

Use of proton pump inhibitors like Lokcid has been seen to be associated with an increase in chromogranin levels. This increase in chromogranin levels can be due to the effect of these drugs on enterochromaffin cells and this could also falsely increase the levels in patients with neuroendocrine tumours.

Use of proton pump inhibitors like Lokcid has been recently linked with the development of dementia in elderly patients. As this risk of developing dementia is not confirmed, talk to your doctor for more information on this effect.

Lokcid may cause vitamin B12 and vitamin C deficiency. When taken orally, vitamin B12 requires an acidic environment for its absorption from the stomach while Lokcid causes a decrease the gastric acid secretion. You may need to take vitamin B12 supplements from outside. The clinical significance of the decrease in vitamin C levels is not known, so vitamin C supplementation is not recommended.

Lokcid before endoscopy in patients with gastrointestinal bleeding reduces the need for endoscopic therapy, the rate of post-endoscopy bleeding, and shortens hospital stays. Hence Lokcid is given before endoscopy in patients with gastrointestinal bleeding.

Q. Is Lokcid better than ranitidine?

Lokcid is a proton pump inhibitor (PPI) and ranitidine is an H2 blocker. Both lowers the amount of acid in your stomach, treats heartburn, and heals ulcers. Studies have shown that Lokcid is more effective than ranitidine in resolving heartburn in patients with gastroesophageal reflux disease (GERD), rapid healing of ulcers and prevent ulcers in patients who use nonsteroidal anti-inflammatory drugs (NSAIDs). However, the effect of these medicines may vary upon individual response.

Q. Are there any withdrawal symptoms associated with the use of Lokcid?

There are no withdrawal symptoms seen when patients stop using Lokcid as it has no habit forming tendencies.

Lokcid can cause magnesium deficiency in the blood. Low magnesium levels is a rare side effect seen in patients treated with Lokcid for at least three months and in most cases after a year of therapy. The patient may have symptoms like tetany, arrhythmias, and seizures and may need to stop this medicine and take magnesium from outside. Magnesium levels should be tested at regular intervals in the patients taking Lokcid for a long duration.

Patients with cardiac disease can take Lokcid. However, Lokcid can interact with certain drugs (e.g clopidogrel, digoxin) which might be used by a patient with an underlying cardiac disease. Patients taking Lokcid and digoxin may need to be monitored for digoxin toxicity. Lokcid decreases the activation of clopidogrel, thus reducing its effects. Patients taking these medicines together needs to be monitored closely by a doctor.

Use of Lokcid can cause iron deficiency and a decrease in hemoglobin levels as it decreases the acidic environment of the stomach needed for the absorption of iron. However, there are no recommendations on the regular monitoring of iron levels or taking iron supplements when the patient is taking Lokcid.

Q. How is Lokcid different from esomeprazole?

Lokcid and esomeprazole both belong to the same class of drugs and are used in disease conditions with excess acid production like heartburn, acidity, stomach ulcers and intestinal ulcers. Esomeprazole is an S-isomer of Lokcid. Studies have shown that esomeprazole provides more effective and rapid acid control than Lokcid, without any increase in side effects and fewer variations in response between different patients.

Lokcid is a not a narcotic substance and has not been reported to have any abuse potential. Lokcid does not get you high and does not cause any addiction as no withdrawal symptoms have been reported when you stop taking this drug.

Lokcid is metabolized in the liver by the cytochrome P450 enzymes mainly CYP2C19. There could be an increase in the level of Lokcid in patients with underlying liver disease because of a decrease in its metabolism. However, the amount of drug does not increase if given once a day.

Lokcid can be used in stroke patients. There are studies suggesting that proton-pump inhibitors (PPIs) as a class are not associated with an increased short-term risk of recurrent stroke or death among older adults treated with clopidogrel after stroke.

Q. How is Lokcid better than cimetidine?

Lokcid is a proton pump inhibitor and cimetidine is an H2 receptor blocker. They act in different ways but both decrease the acid production in the stomach. However, Lokcid is more potent, longer acting, and has fewer adverse effects when compared to cimetidine.

Q. Is Lokcid better than rabeprazole?

Lokcid and Rabeprazole belong to the same class of medicines known as proton pump inhibitors (PPIs) and work in the same way to decrease acid production in the stomach. However, few clinical studies have shown that rabeprazole provides better relief of the symptoms including the daytime pain of duodenal ulcers. The difference in response may also vary in different patients

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User Submitted Feedback For Lokcid 20mg Capsule

Patients taking Lokcid 20mg Capsule

Once A Day

100%

What were the side-effects while using this medicine?

No Side Effect

100%

How do you take this medicine?

Empty stomach

100%

How much was the improvement?

Average33%

Poor67%

Please rate this medicine on price?

Average33%

Expensive67%

What are you using this medicine for?

Acidity

100%

Survey Participants: 3

Disclaimer

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