Oregon led 21-0 after the first 10 1/2 minutes, took a 28-10 lead into halftime and built its advantage to 45-10 before the end of the third quarter.

The offense failed to finish some scoring opportunities  a two-minute drill at the end of the half ended with Virginia stuffing Oregon's fourth-and-goal run attempt from the 1-yard line  but the Ducks still finished with 557 yards.

Oregon forced four turnovers, one an interception that Dior Mathis returned 97 yards to set up a second-half touchdown.

Marcus Mariota completed 14 of 28 passes for 199 yards and two TDs and ran four times for 122 yards and a TD (a 71-yard burst on Oregon's first possession).

De'Anthony Thomas ran 11 times for 124 yards and three TDs -- on scampers of 1, 40 and 8 yards.

Freshman Thomas Tyner from Aloha High made his debut in the fourth quarter and put himself into the box score with two TD runs. He got into the end zone on a 3-yard power play immediately after Mathis' interception runback. Tyner then sprinted untouched through a huge hole up the middle for Oregon's final TD, a 31-yard ground play with 7:28 remaining. He wound up with four carries for 51 yards.

Bralon Anderson and Keanon Lowe each had a touchdown catch for the Ducks (2-0). Addison, Lowe and Josh Huff had three catches apiece, as eight Ducks caught at least one pass.

Oregon's offense did not commit a turnover, and the Ducks' defense gave up 298 yards (174 passing and 124 rushing, 3.2 yards per run).

Virginia fell to 1-1.

Oregon's nonconference schedule continues next Saturday, Sept. 14, as the Ducks play host to Tennessee at 12:30 p.m. PT.