Browse our anti-NDST1 (NDST1) Antibodies

On www.antibodies-online.com are 48 N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1) Antibodies from 10 different suppliers available. Additionally we are shipping NDST1 Proteins (8) and NDST1 Kits (7) and many more products for this protein. A total of 65 NDST1 products are currently listed.

More Antibodies against NDST1 Interaction Partners

Compound heterozygous mutations in NDST1 were identified, in the heparan sulfate N deacetylatase domain of one allele and the sulfotransferase domain of the other allele. This report expands the phenotypic spectrum of Ndst1 deficiency in humans.

Among the genes enriched in this screening, the authors found that TM9SF2 (show TM9SF2 Antibodies) is critical for N-sulfation of heparan sulfate and therefore for chikungunya virus infection because it is involved in the proper localization and stability of NDST1.

Our data confirm NDST1 mutations as a cause of autosomal recessive intellectual disability with a distinctive phenotype, and support an important function of NDST1 in human development.

demonstrate the essential role of domain cooperation within NDST-1 in producing HS with specific domain structures

Upregulation of NDST1 is associated with chemoresistance in breast cancer.

These findings establish NDST1 as a target of miR (show MLXIP Antibodies)-24 and demonstrate how such NDST1 suppression in endothelial cells results in reduced responsiveness to VEGFA (show VEGFA Antibodies)

The results of this study suggested that while Chst14 (show CHST14 Antibodies) and its enzymatic products might be of limited importance for neural development, they may contribute to the regeneration-restricting environment in the adult mammalian nervous system

embryonic stem cells lacking both NDST1 and NDST2 (show NDST2 Antibodies), expressing a very low sulfated (show SULF1 Antibodies) heparan sulfate, can take the initial step toward differentiation into all three germ layers

Deletion of N-deacetylase-N-sulfotransferase1 in smooth muscle did not influence any of the blood pressure parameters measured despite significant decrease in aorta and thoracodorsal artery luminal area.

Lowered expression of NDST1 also results in a higher sulfate content of the heparin synthesized and is accompanied by increased levels of stored MC proteases.

Inhibitory peptides of the sulfotransferase domain of the heparan sulfate enzyme, N-deacetylase-N-sulfotransferase-1.

These data provide new evidence that modification of heparan sulfate fine structure through deletion of Ndst1 is sufficient to decrease vascular smooth muscle cell proliferation and alter vascular remodeling.

NDST1 Antigen Profile

Antigen Summary

Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis (By similarity).