The Diocese of Eastern Pennsylvania is a diocese of the Orthodox Church in America. Its territory includes parishes, monasteries, and missions located in two states in the United States – Delaware and Pennsylvania. The diocesan chancery is located in South Canaan Township, Pennsylvania.

The diocese is currently under the leadership of His Grace, the Right Reverend Tikhon (Mollard) of Philadelphia. He was consecrated as a bishop on February 14, 2004, and installed as the ruling bishop of the diocese of Philadelphia and Eastern Pennsylvania on October 29, 2005.