Immunohistochemistry of tumor cell proteins will be performed on prostate biopsies to detect for androgen receptors and other protein products related to oncogenes or tumor suppressor genes thought to play a role in radiation or ADT.

DNA sequencing will be performed on prostate tumor DNA to determine the mutational status of several oncogenes and tumor suppressor genes including genes coding androgen receptors.

RNA sequencing will be performed on several oncogenes and tumor suppressor genes including genes coding androgen receptors to detect RNA expression including genes related to the androgen receptor.

375

Male

18 Years and older (Adult, Senior)

NCT03296124

UFPTI 1612- PRX32IRB201700018

PRX32

December 7, 2017

September 2020

September 2020

September 28, 2017

December 12, 2017

University of Florida Proton Therapy InstituteJacksonville, Florida, United States