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The wire brush is primarily an abrasive implement, used for cleaning rust and removing paint. It is also used to clean surfaces and to create a better conductive area for attaching electrical connections, such as those between car battery posts and their connectors, should they accumulate a build-up of grime and dirt. When cleaning stainless steel, it is advisable to use a stainless steel bristle wire brush, as a plain carbon steel brush can contaminate the stainless steel and cause rust spots to appear. Brass bristle brushes are used on softer surfaces or in potentially flammable environments where non-sparking tools are required. Wire brushes are also used to clean the teeth of large animals, such as crocodiles and pigs. They are also used widely in surface engineering to clean the castings to paint the castings.

A number of surgeons recommend that wire brushes not be used to clean barbecue grills.[1] In some cases, bristles break off the brush which then become deposited in food cooked on the grill. Ingestion of these bristles can cause gastrointestinal perforation.[2][3]