Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LS-F8650 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the detection of Human TERF2IP / RAP1 in samples of Tissue Homogenates. It is based upon a Sandwich assay principle and can be used to detect levels of TERF2IP / RAP1 as low as 0.66 nanograms per millilter.

Intended Sample Types:

Tissue Homogenates

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Detection Range:

1.56 - 100 ng/ml

Sensitivity:

0.66 ng/ml

Assay Time:

4.5 h

Precision:

Intra-Assay: CV<10% Inter-Assay: CV<12%

Quality Assurance:

Due to their limited shelf life, LSBio ELISA kits are not typically stocked as finished goods. Upon receipt of an order each kit is assembled and tested to ensure that it meets specifications before shipping. Minor changes may occur to the Range, Sensitivity, and Precision. In the event of a significant change the order would be confirmed with the customer before shipping ELISA kit lot numbers reflect the date of final assembly and testing for each specific kit rather than a bulk manufactured lot. All kits are tested to confirm that they fall within their defined Inter- and Intra- assay coefficient of variation.

Kit Components:

Coated 96-well Strip Plate

Adhesive Plate Sealers

Standard (Lyophilized)

Sample Diluent

Detection Reagent A (Green)

Detection Reagent B (Red)

Assay Diluent A

Assay Diluent B

TMB Substrate

Stop Solution

Wash Buffer (30x concentrate)

Storage:

Short term: 4°C; Long term: see manual.

Restrictions:

For research use only.

About TERF2IP / RAP1

Description: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair.