SAN FRANCISCO -- Colin Kaepernick passed for 243 yards and two touchdowns in his first career start in place of the injured Alex Smith, and the San Francisco 49ers whipped the Bears 32-7 on Monday night in a highly touted NFC showdown that hardly lived up to the hype.

Kaepernick threw touchdown passes to Vernon Davis and Michael Crabtree, and Kendall Hunter ran for a 14-yard TD as San Francisco (7-2-1) jumped out to a big lead by scoring on each of its first four possessions -- with Aldon Smith wreaking havoc on the other side of the ball with five sacks.

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The 7-3 Bears' Jason Campbell, the other quarterback in this matchup of backups for two division leaders, threw a 13-yard touchdown pass to Brandon Marshall in the third quarter but was sacked five times and threw two interceptions in his first start since October 2011 for Oakland.

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