What’s in Your Medicine Cabinet?

Tips to Avoid Possible Interactions with Existing Medications

Nearly all pulmonary hypertension patients take at least one drug specifically used to treat their PH. In addition, patients may also receive one or more general therapies given to supplement the PH medication. The combination of all these therapies places the patient at an increased risk for drug-drug interactions, and therefore, these therapies are carefully monitored by a patient's physicians, nurses and pharmacists. For example, anticoagulants, such as warfarin (Coumadin®), help prevent clotting complications sometimes seen with PAH. With this therapy, patients are required to have routine lab work to monitor and maintain adequate blood clotting time.

In addition to prescribed treatments, some patients may choose to obtain other products such as herbal supplements, vitamins and other over-the-counter (OTC) products used for cough/cold and pain. Because these products are available in health food stores and pharmacies without the need of a prescription, many patients are unaware of the potential risks and interactions associated with these products. Vitamin supplements have the potential to interact with prescribed medications and could decrease the medications’ effectiveness or increase the side effects.

Here are some important points regarding the use of OTC medications, vitamins and herbal products as they relate to pulmonary hypertension:

Although often considered harmless, no product available without a prescription should be taken BEFORE consulting with your physician, nurse or pharmacist.

Dosages listed on the OTC container should not be exceeded without consent or discussion with your physician.

The following popular herbal products have documented interactions:

»»Ginkgo biloba, often used to improve memory and brain function, is associated with increased bleeding episodes and, therefore, interferes with anticoagulant therapies.

»»Flaxseed, often used as a laxative and to lower cholesterol levels, has been known to interact with cardiac medications, increasing their levels in the bloodstream and increasing effects and side effects.

To summarize, most OTC preparations, vitamins and herbals can be taken safely and without effect. However, before purchasing these products, it is important to consult with your physician, nurse or pharmacist and provide them with a complete list of all current medications. After a careful review, your healthcare professional can best advise you on the appropriate medications to take to prevent any unwanted interactions or therapy complications.

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The information provided on the PHA website is provided for general information only. It is not intended as legal, medical or other professional advice, and should not be relied upon as a substitute for consultations with qualified professionals who are familiar with your individual needs.