Cristhiaan Ochoa, MD

Summary of Research Project:

Thrombospondin-1 in Hypoxic Pulmonary Vascular Remodeling

With PHA’s grant money Dr. Ochoa is exploring the properties of a protein called thrombospondin-1. Previous researchers had hypothesized that thrombospondin-1 acted as a protective agent in the lungs, and Dr. Ochoa is determined to prove this hypothesis. Dr. Ochoa tests his theories in mice by inducing hypoxia (decreased levels of oxygen in the blood). His project involves comparing mice without the thrombospondin-1 gene to normal mice after inducing hypoxia in both groups.

Biography

Dr. Ochoa attended medical school in his native country at Universidad Pontificia Bolivariana in Medellin, Colombia. It was in medical school as a TA for a pulmonary physiology class that he first became interested in pulmonary hypertension. When it came time to decide what to do for research in his last year in school, he decided to work with Dr. Charles Hales and Dr. Deborah Quinn at Massachusetts General Hospital/Harvard Medical School in their pulmonary and critical care lab. “I got hooked,” he says of his first hands-on experience with pulmonary hypertension research.

For optimal viewing of PHAssociation.org, please use a standards-compliant browser such as Google Chrome or Firefox.

The information provided on the PHA website is provided for general information only. It is not intended as legal, medical or other professional advice, and should not be relied upon as a substitute for consultations with qualified professionals who are familiar with your individual needs.