Decimating the Sicilian is not hard, provided you are much better prepared than the opponent in the given line, and the position is somewhat sharp. Take games such as Anand-Vachier Lagrave, Norway Chess 2015, or Radjabov-Grischuk, FIDE GP 2015.

If you are prepared to move 40 and still not achieving the desired decimation, the 1.Nf3 c5 2.e4 move order may provide the necessary boost to your results against this opening.