The Treasury's Office of Foreign Assets Control also designated eight Argentine nationals and nine entities located in Argentina, Colombia, Canada, Britain and the Netherlands for their roles in Goldpharma, the agency said in a statement.

The study in JAMA Psychiatry published by the American Medical Association found children whose parents were prescribed opioids were twice as likely to attempt suicide as the offspring of people who did not use those drugs.

At least twice in recent months, eight members of the Sackler family who own OxyContin maker Purdue Pharma LP have been at odds over how to respond to allegations implicating them in deceptive marketing of prescription painkillers that led to widespread fatal overdoses, said people familiar with the matter.

The settlement announced by West Virginia Attorney General Patrick Morrisey on Thursday came in one of hundreds of similar lawsuits by states and local governments against McKesson and other distributors over their roles in the opioid crisis.

John Kapoor, who served as the Arizona-based drugmaker's chairman, and his co-defendants are the first executives of a painkiller manufacturer to face trial for conduct that authorities say was tied to the deadly opioid crisis.

Pharmaceutical company Purdue Pharma agreed to pay $270 million to the state of Oklahoma in one of the more than 1,600 lawsuits it faces for its alleged responsibility in aggravating the opioid crisis in the US.

Cleveland County District Judge Thad Balkman's decision was a win for the state, even as one of the lawyers for the state said Purdue had "threatened" to file for bankruptcy rather than face the first trial to result from around 2,000 lawsuits nationally.

Experts say Tramadol is used with caution in case of children and is not for use in case of infants. Tramadol is an opioid painkiller, which directly affects the brain and alters how the body feels and responds to pain.

OxyContin maker Purdue Pharma LP is exploring filing for bankruptcy to address potentially significant liabilities from roughly 2,000 lawsuits alleging the drugmaker contributed to the deadly opioid crisis sweeping the United States, people familiar with the matter said on Monday.

A study from investigators at the Massachusetts General Hospital (MGH) Institute for Technology Assessment projects that the opioid overdose epidemic in the U.S. is likely to increase in coming years, and that measures based on restricting access to prescription opioids will have a minimal impact in reducing overdose deaths.

Consumption of food contaminated with Salmonella can cause salmonellosis, one of the most common bacterial food-borne illnesses. The most common symptoms of salmonellosis are diarrhea, abdominal cramps, and fever within 12 to 72 hours after eating the contaminated product.

According to the research published in the journal 'Cancer Prevention Research', the most significant reduction in risk occurred in the first 10 years after quitting, with a modest but continued decline in later years.