Sugarfix 1 - a study of the effects of high blood glucose on the eye and the potential for antioxidant protection Dr Jonathan Noonan BSc(Hons) MBBS PhD.

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Presentation on theme: "Sugarfix 1 - a study of the effects of high blood glucose on the eye and the potential for antioxidant protection Dr Jonathan Noonan BSc(Hons) MBBS PhD."— Presentation transcript:

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Sugarfix 1 - a study of the effects of high blood glucose on the eye and the potential for antioxidant protection Dr Jonathan Noonan BSc(Hons) MBBS PhD Student, CERA

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Sugarfix 1 Purpose To study the effects of high blood glucose levels, with or without vitamin C, on: – Blood vessel function in the eye – Nerve cell function in the eye – Blood vessels in the rest of the body

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Sugarfix 1 Blood vessel function in the eye Flickering light causes blood vessel dilation Less dilation in people with diabetes We are studying how this changes with different blood glucose levels

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Sugarfix 1 Nerve cell function in the eye Looking at a changing checkerboard pattern creates electrical signals These signals are smaller and slower in diabetes This may be due to problems with the ganglion (optic nerve) cells

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Sugarfix 1 Stiffness of other blood vessels Radial artery in the forearm pulses with the heart beat Arteries become stiffer with high blood glucose levels Vitamin C reduces stiffening of arteries during high blood glucose levels

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Sugarfix 1 Progress and future directions 3/12 participants completed (+4 seen once) Expected completion end September 2014 Results of Sugarfix 1 will be used to inform further research with antioxidants in diabetes STAY TUNED!