Dr. Seth Bilazarian discusses a recent paper published in Circulation by Drs. Benedikt Schrage, Karim Ibrahim, et. al. on a retrospective matched-pair analysis comparing patients in cardiogenic shock treated with balloon pump and Impella. Dr. Bilazarian highlights several limitations of the analysis, which used a matched-pair analysis to “harmonize baseline characteristics” of Impella-treated patients with patients included in the IABP-SHOCK II trial.