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Stem Cell Research

21NovemberNov2017one year ago

Spaltro G, Vigorelli V, Rovina D, Nigro P, Pompilio G, Gowran A

Duchenne muscular dystrophy (DMD) is caused by abnormalities in the dystrophin gene and is clinically characterised by childhood muscle degeneration and cardiomyopathy. We produced an induced pluripotent stem cell line from a DMD patient's dermal fibroblasts by electroporation with episomal vectors containing: hL-MYC, hLIN28, hSOX2, hKLF4, hOCT3/4.