Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )

Length:

55

Sequences:

642

Seq/Len:

11.67

HH_delta:

0.916 (20Jul13)

GREMLIN Results:
Residue pairs sorted by strength in covariance:Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

i

j

Raw Score

Scaled Score

10_R

52_R

0.41217

2.113

29_D

32_F

0.41114

2.108

8_D

52_R

0.39138

2.007

41_D

44_Y

0.30477

1.563

8_D

53_G

0.28678

1.470

27_F

37_N

0.27695

1.420

29_D

45_L

0.27646

1.417

30_E

37_N

0.26829

1.375

48_R

51_P

0.26023

1.334

4_C

9_G

0.25298

1.297

43_D

47_W

0.24633

1.263

28_I

33_N

0.24143

1.238

30_E

36_K

0.24103

1.236

24_T

29_D

0.23942

1.227

26_P

35_Q

0.23704

1.215

50_Q

55_D

0.23635

1.212

22_N

45_L

0.2343

1.201

35_Q

44_Y

0.23129

1.186

42_S

47_W

0.2233

1.145

3_R

8_D

0.2207

1.131

13_P

47_W

0.21925

1.124

14_D

55_D

0.21571

1.106

51_P

54_C

0.21454

1.100

3_R

12_V

0.21354

1.095

35_Q

45_L

0.20733

1.063

28_I

32_F

0.20627

1.058

28_I

31_G

0.20598

1.056

39_R

44_Y

0.20582

1.055

33_N

36_K

0.20508

1.051

43_D

55_D

0.20446

1.048

33_N

45_L

0.20106

1.031

3_R

19_L

0.20095

1.030

13_P

36_K

0.19884

1.019

17_Y

32_F

0.19673

1.009

27_F

32_F

0.19525

1.001

3_R

15_P

0.19474

0.998

48_R

55_D

0.18591

0.953

21_T

35_Q

0.18454

0.946

21_T

24_T

0.18368

0.942

32_F

38_G

0.18155

0.931

28_I

42_S

0.17814

0.913

9_G

25_C

0.17709

0.908

23_S

26_P

0.17361

0.890

4_C

7_F

0.17207

0.882

47_W

55_D

0.16905

0.867

28_I

45_L

0.16738

0.858

13_P

43_D

0.16567

0.849

10_R

35_Q

0.16312

0.836

26_P

29_D

0.16237

0.832

20_Y

25_C

0.16142

0.828

14_D

26_P

0.15898

0.815

38_G

41_D

0.15863

0.813

40_P

46_K

0.15858

0.813

19_L

44_Y

0.15737

0.807

6_Y

29_D

0.15676

0.804

3_R

36_K

0.15269

0.783

23_S

30_E

0.15238

0.781

18_P

44_Y

0.15221

0.780

17_Y

21_T

0.15055

0.772

29_D

37_N

0.14934

0.766

6_Y

31_G

0.14932

0.766

26_P

32_F

0.14903

0.764

10_R

50_Q

0.14861

0.762

5_D

20_Y

0.14825

0.760

8_D

31_G

0.14821

0.760

18_P

40_P

0.14744

0.756

15_P

50_Q

0.14616

0.749

8_D

37_N

0.14585

0.748

43_D

46_K

0.14439

0.740

20_Y

41_D

0.14337

0.735

31_G

47_W

0.14027

0.719

21_T

45_L

0.14008

0.718

16_S

53_G

0.13971

0.716

22_N

33_N

0.13958

0.716

21_T

29_D

0.13947

0.715

23_S

53_G

0.13743

0.705

33_N

51_P

0.13673

0.701

12_V

50_Q

0.13667

0.701

9_G

20_Y

0.13666

0.701

22_N

32_F

0.13599

0.697

Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.