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Researchers at Kessler Foundation have studied the measurement tools used in multiple sclerosis for their effectiveness in predicting employment status. They compared the Expanded Disability Status Scale (EDSS), the Multiple Sclerosis Functional Composite (MSFC), the Paced Auditory Serial Addition Task (PASAT), and the Symbol Digit Modalities Test (SDMT), and found the SDMT effective in differentiating employed from unemployed individuals. The article, Unemployment in multiple sclerosis (MS): utility of the MS Functional Composite and cognitive testing, was published in the January 2014 issue of Multiple Sclerosis Journal (doi: 10.1177/1352458513488235). The authors are Lauren Strober, PhD, Nancy Chiaravalloti, PhD, Nancy Moore, PhD, and John DeLuca, PhD, of Kessler Foundation..... Read More - http://www.ms-uk.org/cognition

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The Kurtz EDSS is biased toward the ability of the patient to walk - which will only affect some types of employment.

The PASAT is actually part of the MSFC, so either the MSFC was not administered completely, or one of it's three components was administered a second time. This could well influence any results.

The SDMT is a very widely used test for a whole range of neurological disabilities from Dyslexia on up. Its big problem is that it is particularly sensitive to age and educational experience, and I would think that these would be good predictors of employment status for a wide range of conditions (not just MS).To say that it is the only predictor of employment status, with an accuracy of 67 %, is a fancy way of saying that the study did not produce any useful data - 67% is not a lot better than chance in terms of probability.

This has all the signs of a "scatter-gun" study - throw a set of tests at two groups of subjects and hope that something significant come out.

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