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Protein cross-linking and modification reactions often required carefully controlled reaction conditions as some buffers will interfere with coupling and modification reactions. For example, Tris buffers will interfere with amine coupling reactions.
G-Biosciences offers a selection of optimized buffers designed for specific reactions.
G-Biosciences also offers a reactor system, Tube-O-Reactor™, that is ideal for protein cross-linking and modification reactions.

The conjugation and modification reactions used to cross-link proteins or couple labels to proteins, such as biotin, enzymes, and fluorescent dyes, require certain conditions, including pH and chemica..