ATP is required in glycolysis during the conversion of Glucose to ______ by ______ and in the conversion of fructose 6- phosphate to _____ by _____.

G6P, hexokinase, fructose 1,6 biphosphate, PFK-1

The 3 irreversible reaction enzymes in glycolysis are ____.

hexokinase, PFK-1, and pyruvate kinase

PFK-1 ‘s energy controls are ______ by ATP and ______ by ADP and AMP.

inhibition, stimulation

PFK-1 is inhibited by ____ pH from the formation of _____ and ____ acids during _____.

low, pyruvic, lactic, acidosis

PFK-1 is inhibited by _____, which is a mitochondria metabolite, signaling an abundance of metabolic and energy intermediates.

citrate

The hormonal control of PFK- 1 is _____ by _____ and ____ by ____ in the liver.

stimulation, insulin, inhibition, glucagons

Hormone regulation in glycolysis occurs by glucgon _____ cAMP, which inhibits ______ which inhibits ____ which further inhibits the formation of _____ which is an allosteric activator of PFK-1.

stimulation, protein kinase A(PKA) , PFK-2, Fructose 2,6- biphosphate

Hormone regulation in glycolysis occurs by insulin inhibition of ______ so that _____ is not stimulated, but instead _____ is stimulated to produce fructose 2,6-biphosphate which is an allosteric activator of ____.

cAMP, Protein kinase, PFK-2

Fructose 1,6-biphosphate is converted by _____ to ______ and ______, which can interconvert by _______.