TaqMan Drug Metabolism Assay Sets

TaqMan™ Drug Metabolism Genotyping Assay Sets are predefined collections of TaqMan DME Genotyping Assays and TaqMan™ Copy Number Assays for specific DME gene targets. These sets were derived from public databases, consortiums, and published articles. Predefined sets of assays greatly simplify the study of key DME variants. The assays are delivered in individual tubes to either run a subset of assays or the entire set.

Table 1: List of Currently Available Assay Sets

Set Name

Set Information

PharmaADME Core Marker Set

The PharmaADME consortium (www.PharmaADME.org) created a consensus list of the known and likely functional variation present in key DME genes. The most important ADME genes can be grouped into four categories: Phase I and II metabolism enzymes, transporters, and modifiers. The Core Marker list is the list of variants in these genes that are considered to be most important. This assay set is comprised of both TaqMan® DME and Copy Number Assays.