Upon discovering that she is half werecat, Pippa Reyes sets off across America to find a new home, rumored to be a safehold for her own kind. But, as she and her band of friends travel the feral cities of the United States, Dr. Jack Tanner has suspicions that they are in possession of a cure that could end the feral infestation that has swept the nation. A series of unfortunate events threatens the mission, and after suffering the deaths of several friends, Pippa's anger unleashes something hidden deep within herself, something far worse than the feral beasts that roam the barren lands. Pippa Reyes has become a rabid—a maniacal killing machine, so insane and bloodthirsty that she now hunts the very ones who are searching for her.