If you rely on federal programs for housing, education and vaccinations for your young child, you should be worried.

If you're a teacher, be concerned for your job. If you're a researcher at UCSF, think about the number of research programs being cut. If you're planning to fly in or out of SFO, Oakland or San Jose, you could be facing cancellations, delays and long lines at security.

It's the result of a deal struck two years ago that if Congress couldn't pass a long-term deficit-reduction plan, there would be $1.2 trillion in nonnegotiable spending cuts spread over 10 years, beginning in January, then postponed to March 1.

And here we are, in what might be called "Fiscal Cliff 2," only this time California faces $4 billion in cuts this year alone, thanks to what is the latest politically manufactured crisis in Washington.

It will take some time for the rerun to unspool - the exact timing of the cuts has yet to be worked out - but dozens of programs Californians rely on are on the hook to lose all or a substantial amount of federal funding.

And don't look for Sacramento, which only recently got its budget act together, to ride to the rescue.

"I can't discern what they are going to do in Washington because I don't even know if they know themselves," said Gov. Jerry Brown, when asked about sequestration last week. "But the takeaway for California is that we have to maintain a proven surplus, because we could lose hundreds of billions of dollars by decisions that Congress makes."

The biggest hit to California will be an estimated $3.2 billion cut in military spending on procurement, wages and grants, according to numbers compiled by Federal Funds Information for States, a service created by the National Governors Association and the National Conference of State Legislatures. That hurt will be felt primarily in Southern California, by military families and defense contractors.

In addition to the defense cut reverberations, Los Angeles officials estimate that the city will lose up to $115 million in federal money for job training, after-school programs, housing assistance and public safety in the first six months of sequestration alone.

San Francisco's latest estimate of cuts to city services, including the school district and Housing Authority, exceeds $25 million, said Francis Tsang, a spokesman for Mayor Ed Lee. Dozens of the city's teachers and school employees would be among the estimated 1,800 in California facing the sequestration ax, according to the National Education Association. School districts in other parts of the Bay Area would face similar cuts.

How SFO and other local airports will be affected remains to be seen. Under sequestration, the majority of the Federal Aviation Administration's 40,000 workers would face temporary furloughs, Transportation Secretary Ray LaHoodsaid this week. "The result will be felt across the country, as the volume of travel must be decreased," he said.

Statewide, cuts in nondefense spending programs would total $670 million in 2013, according to FFIS, whose data are being reviewed by the California Department of Finance. Separate cuts in National Institutes of Health funding amount to $177.5 million, which could result in 3,000 jobs lost statewide, according to a United for Medical Research report.

California school districts stand to lose $92 million in Title 1 grants and $66.5 million in special education money. Other losses include $48 million in National Science Foundation grants, $5 million for California firefighters and other first responders, and less money for food safety inspections and breast cancer screenings.

UCSF, the largest recipient of NIH money in the nation, stands to lose $28 million in funding this year. That could put an end to as many as 264 research programs, one quarter of UCSF's current total, said Sam Hawgood, dean of UCSF's School of Medicine. It's facing additional millions in cuts to Food and Drug Administrationand Medicare funding.

"We're very concerned, for the short term and long term," said Hawgood. "We'll be forced to shut down programs that take years to rebuild. It could also be discouraging for the next generation of students wanting to go into science and biotech, which much of the Bay Area economy is based on."