In order to analyze the characteristics of blasting vibration and collapse vibration caused by blasting demolition of high-rise buildings and the impact on the surrounding buildings, the actual measurement to the ground vibration of high-rise RC building blasting demolition was carried out, and the peak ground velocity, peak frequency, duration and response spectrum was analyzed. The conclusions are drawn that collapse vibration has greater effect than blasting vibration and its frequency is lower, which is more likely to cause resonance of buildings; the vertical component peak of collapse vibration velocity is the largest, and the attenuation of that is the rapidest along with the increase of the distance. Blasting vibration also has the same law; the commonly-used formulas for calculating collapse vibration cannot estimate reasonably on the different directions of collapse; comparing the response spectrum of each point with the designed spectrum, it is explained that this blasting demolition didn’t cause substantial damage to the surrounding buildings from the aspect of seismic design.