Application Information: Protein C antibody

Not yet tested in other applications. Optimal dilutions should be determined experimentally by the researcher.

Form Supplied

Liquid

Concentration

5
mg/ml
(Please refer to the vial label for the specific concentration)

Purification

Affinity purified by Protein G.

Specifications: Protein C antibody

Full Name

protein C (inactivator of coagulation factors Va and VIIIa)

Product Description

Sheep Polyclonal antibody to Protein C

Background

This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.