Abstract

A short and efficient method was developed for the synthesis of 2-benzoxepin-3(1H)-ones. The synthetic sequence comprises of initial intermolecular Heck coupling, followed by reduction of the carbonyl functionality of the Heck product and finally base-induced intramolecular condensation. Notably, the final condensation may proceed by an interesting oxy-Michael addition, cycloreversion via double bond isomerization and intramolecular condensation.

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IITH Creators:

IITH Creators

ORCiD

G, Satyanarayana

UNSPECIFIED

Item Type:

Article

Additional Information:

Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0034-1379901.