Patients with Parkinson's disease (PD) are known to suffer from motor symptoms of the disease, but they also experience non-motor symptoms (NMS) that are often present before diagnosis or that inevitably emerge with disease progression. The motor symptoms of Parkinson's disease have been extensively researched, and effective clinical tools for their assessment and treatment have been developed and are readily available. In contrast, researchers have only recently begun to focus on the NMS of Parkinson's Disease, which are poorly recognized and inadequately treated by clinicians.

The NMS of PD have a significant impact on patient quality of life and mortality and include neuropsychiatric, sleep-related, autonomic, gastrointestinal, and sensory symptoms. While some NMS can be improved with currently available treatments, others may be more refractory and will require research into novel (non-dopaminergic) drug therapies for the future.

Edited by members of the UK Parkinson's Disease Non-Motor Group (PD-NMG) and with contributions from international experts, this new edition summarizes the current understanding of NMS symptoms in Parkinson's disease and points the way towards future research.

Overview:

The most comprehensive and up to date textbook available focusing on non-motor symptoms of Parkinson's disease: from the bench to bedside as well as spanning per-motor Parkinson's to advanced motor Parkinson's

Contributions from international experts ensure a truly global approach to the subject

This fully updated and expanded new edition will include several new chapters including:

NMS symptons as markers of Parkinson's disease risk

Thermoregulatory dysfunction

The neural substrate of NMS in Parkinson's disease

Sleep-disordered breathing in Parkinson's disease

The non-motor effects of continuous-drug-delivery based strategies in the treatment of Parkinson's disease