Guido has visited, and revitalised, a number of rural or marginalised towns across the globe.

A year ago, he headed out to the rural NSW town of Manildra to paint on a series of working freight trains.

He did it so families in rural towns, that mightn't get the opportunity to visit Australian cities and their museums, would have the opportunity to see street art.

But it isn't just silos and trains that the Brisbane artist paints.

Guido's incredible process of creating a massive jigsaw with a handful of shipping containers was unveiled in Dubai in May last year.

The installation took a total of 288 hours to complete and was eventually inspired by a man Guido came across working near the construction site.

And next on Guido's hit list is a mammoth project in his own state.

As a Southern Cross University alumnus, it seemed inevitable that Guido would eventually return to paint one of his old uni's buildings.

While Guido studied at the Lismore campus of Southern Cross University, the Gold Coast section of the uni and its 10-storey building will be the place lucky enough to score a Guido exclusive.

The campus is next-door neighbours with the Gold Coast airport meaning the mural won't just be visible from the beach and the uni - anyone flying in or out of the Queensland destination will be able to see it from their plane.

Guido will start painting the 43-metre high blank canvas on March 6 and will take at least two weeks to complete the mammoth painting.

"What is most interesting about this project is reflecting people's connection with their built environment, which in my previous work has often been on industrial sites, but in this case it's a social and very interactive modern space where people come to learn and grow," Guido said.

Guido is heading back to his home state to paint his latest mural.

But of course, before he does all that, Guido will spend time at the university and in the Gold Coast, trying to figure out who he'll paint.

It'll always be a mystery though - a number of people Guido has forever immortalised as a mural have been kept secret.

"If you leave the anonymity to these people and people see whoever they want to see, they can have their own connection to the work," he told ABC after dozens of people raised questions about his Brim stars.

But when it comes to the Gold Coast, Guido is also planning on relying on the space.

"I work by bringing a lot of influence from the site, so I want to use that style of architecture and that modern look to influence the design in a way that suits the site and place. It will be something that is very different to what I've done before, which I'm excited about."

Guido's work of art will be finished just in time for the Commonwealth Games, which are due to kick off on the Gold Coast on April 4.

And a similar story to the way Guido conducts his career has also been nominated for an Oscar at this year's Academy Awards.

Faces Places, a French documentary directed by Agnes Varda and JR, follows the two artists travelling around rural France where they create portraits and murals of people they come across.

The film, described as an "unassuming masterpiece", mirrors the way Guido revitalises and listens to the voices of people living in rural or often marginalised communities.

Guido's Gold Coast mural is expected to be finished by March 17.

The artist doesn't just paint in Australia. This is work he did in Dharavi.