Datasheet Extract

IL-22 is a member of the IL-10 family of regulatory cytokines. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10R-beta/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family.

Lyophilized product is stable at room temperature for one month, should be stored desiccated below -20 °C. Upon reconstitution IL22 should be stored at 2 - 8 °C up to one week and at -20 °C for longer. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.Shelf life: one year from despatch.