I have Win 7 Ult 64bit, Calibre 2.8 and the same issue as Dchiplin. When I change the dlls and then start Calibre, IOS Reader Applications is advised as missing. If I try to connect my iPhone 4s at this point nothing happens, if I try instead to install IOS RA this does not work.

I appreciate all the work that is going into fixing this problem - hopefully we are nearly there now!