Rapid Tagging Of Biomolecules

By adapting a cycloaddition reaction that has never been used in biological systems, chemists have developed an exceptionally fast method for labeling biomolecules such as proteins. The advance could aid the study of dynamic processes in living systems.

Biomolecules inside cells usually exist at low concentrations. To get a glimpse of cellular goings-on, researchers label biomolecules with fluorescent or other tags. The tagging must be fast to be useful in living systems, says University of . . .