This system is currently being upgraded. Upgraded version is expected to
be release in the second half of 2010.

WHAT IS
FILMex TS?

FILMex TSis the first comprehensive,
interactive program that deals with trouble shooting the modern
Film-Coating Process, and provides insight into the major problems that
plague the pharmaceutical industry today.

FILMex TShas been designed by
Pharmaceutical Technologies International, Incorporated (PTI, Inc) as a
tool that can be placed right at the heart of problem-solving
initiatives within any company worldwide.

Although
FILMex TS Release 1 has been designed by PTI on the basis of the extensive
experience that we have in the area of film coating technology, FILMex TScan be further
customized to suit the needs of any individual company.

How does FILMex TS
work?

The program guides
the user through the process of problem resolution by providing:

Illustrations &
photographs that aid in identifying each specific problem.

Overviews of the
background constituting the basis for each problem

Definitions of
key technical terms associated with each problem

Measurement
methods that may be used to quantify specific problems

Appropriate
bibliography relevant to each problem and its resolution.

Recommendations
as to how the problem may be resolved.

Type of coating
problems Covered in FILMex TS Release 1:

Loss of Logo
Definition

Coating pulled
from logo as a result of core expansion

Erosion of
tablet surface in vicinity of logo

In-filling of
logo

Logo bridging

Tablet Erosion

Edge erosion
and edge chipping

Crown
erosion

Erosion
around logo

General
surface erosion

Tablet Breakage

General
tablet breakage

Breakage due
to capping/lamination problems

Poor Color
Uniformity

Tablet-to-tablet color variation

Uneven color
distribution across tablet surfaces

"Speckling"
due to poor pigment distribution

"Blotchiness" due to material bleed through from core

Film Cracking

Catastrophic
cracking

Edge
cracking

Cracking due
to core expansion

Cracking due
to presence of pigments

Film Peeling

Peeling due
to over-wetting and/or tablet rubbing

Peeling due
to film adhesive/cohesive failure

Film
Discontinuities

Discontinuities due to surface eruptions

Film Flaking

Picking

Film Roughness

"Orange
peel" roughness

Roughness
due to over-wetting and film rubbing

Adherence
between coated products

Tablet
twinning

Agglomeration of mult-particulates

Resolution for a
problem:

Resolution for each
problem covered are discussed, where appropriate, in terms of
opportunities to modify: