Metcalf plays Juliana Smithton, a successful neurologist whose life seems to be coming unhinged. Her husband (Daniel Stern) has filed for divorce, her daughter (Zoe Perry) has eloped with a much older man (John Schiappa), and her own health is in jeopardy. But in this brilliantly crafted work, nothing is as it seems. Piece by piece, a mystery unfolds as fact blurs with fiction, past collides with present and the elusive truth about Juliana boils to the surface.