Sub-Telomeric

Introduction

Telomeres are specialized DNA-Protein structures containing long stretches of (TTAGGG) in repeats at the end of all chromosomes. They protect chromosomes from degradation and end-to-end fusion with other chromosomes. The region adjacent to sequences containing telomeric repeats is called the sub-telomer which has been found to be relative gene-rich. Cytogenetic analysis of sub-telomeric regions is difficult due to low resolution using conventional banding techniques.

Note: All probes in the ST range have not shown any cross-hybridization to other chromosomal regions. However, it cannot be excluded that certain sequence polymorphic could still exist. If any unusual hybridization patterns are observed please contact us at kreatech-support@leicabiosystems.com.