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Generic Wellbutrin SRВ® (bupropion) is a sustained-release antidepressant used to treat major depressive disorder and seasonal affective disorder. This medicine works by blocking the reuptake of norepinephrine and dopamine in the brain, thereby helping to balance specific natural substances in the brain called neurotransmitters.

Generic Wellbutrin SR is a norepinephrine and dopamine reuptake inhibitor, or NDRI for short. NDRIs affect specific chemicals within the brain known as norepinephrine and dopamine. The active ingredient, bupropion The FDA approved bupropion in December 1985.

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