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Studies Find Supplement
Users Tend to Weigh Less and Experience Less Hunger

An article published online ahead of print
recently in the British
Journal of Nutrition revealed the finding of Canadian researchers
that consumers of nutritional supplements, particularly men, weigh less on
average than those who don't use the supplements. Additionally, a
second study reported in the article found an appetite suppressive effect in
women associated with multinutrient supplementation.

For the first investigation, Dr. Angelo
Tremblay of Laval University and colleagues analyzed responses to a
questionnaire and dietary and physical activity diary completed by 267 men
and 320 women aged 20 to 65 who participated in phase 2 of the Quebec Family
Study. Resting energy expenditure and body weight were measured, and
body density, body fat, and fat mass were calculated. A subgroup of
participants was questioned concerning dietary restraint, dis-inhibition, and
susceptibility to hunger (a measure of an individuals ability to cope
with feeling hungry).

In the second study, 63 obese men and women
with no nutritional supplement use within six months of beginning the study
were enrolled in a weight loss program for 15 weeks. Participants
received individualized daily calorie targets, and were divided to receive a multinutrient supplement or a placebo for the duration of the study.

The first study revealed significantly lower
weight, fat mass and body mass index among male supplement users after
adjusting for various factors, as well as greater resting energy
expenditure. These characteristics were also found among female
participants, but were less pronounced. In the subgroup analysis, women who
reported that they consumed supplements were found to have significantly
lower disinhibition and hunger, while mens slightly reduced scores in
these areas were not considered statistically significant.

Although the second study did not find
increased weight loss among multinutrient supplement users compared with
nonusers, it did find a reduction in appetite among women who used
supplements, which could be useful in helping women cope with the increase
in hunger that accompanies dieting and weight loss.

Because some nutrients are involved in the
synthesis of peptides and neurotransmitters that control food intake,
decreased intake of these vitamins and minerals may interfere with signaling
pathways involving appetite. Additionally, sub-optimal micronutrient
intake could result in signaling to the brains centers to increase food
intake so that the body's needs for these nutrients might be met.

These results strengthen the plausible
role for vitamins and minerals in the control of appetite and ultimately
energy intake, the authors write.

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