A-Z Health Topics

Acromegaly

Definition

Growth hormone (GH) controls the growth of soft tissue and bone. Elevated GH causes an excess of bone and soft tissue growth. In adults, this can cause a rare disorder called acromegaly. It can cause serious complications and early death if not treated.

In young children, bone growth is still occurring. Excess GH can cause a similar condition called gigantism. Gigantism causes dramatic growth in children.

Causes

The pituitary gland is a small gland located at the base of the brain. It produces many hormones, including GH.

In most cases, the elevation of GH is caused by a benign
tumor
of this gland. In a small number of cases, cancerous tumors of other organs, such as the pancreas, adrenal, or lung, may be the source of excess GH.

Diagnosis

You will be asked about your symptoms and medical history. It is helpful for the doctor to have pictures of yourself when you were younger. A physical exam will be done. Acromegaly is often not diagnosed until years after it begins.

This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.