Dynamic contrast enhanced MRI is commonly used to
detect and characterize lesions. In this work, a method named Sparsity and
Low-Rank enhanced SPIRiT (SLR-SPIRiT) is proposed to push the limit of
spatial-temporal resolution in 3D DCE MRI. SLR-SPIRiT exploits parallel
imaging, transform-sparsity, and locally low-rank property in the dynamic
image series to reconstruct highly accelerated DCE datasets. The proposed
method has been validated on a pediatric DCE dataset with 1x1x2 mm3 spatial
resolution and 3-second temporal resolution (actual acceleration 19.7).