My wife is taking it under our Doctor's direction.
NADH is essential for the nervous system and the brain.
Refer to Depression Free for Life, An All Natural 5 Step Plan to reclaim Your Zest for Living. By Gabriel Cousens, M.D.

Wow I found out what I was missng out on after taking these NADH capsules for the past 3 weeks.I have increased energy levels,certainly more motivation and concentration and a better general feeling of wellness.It has certainly helped pick me up after side effects of Hepatitis C treatment and at 55years of age it is great to have the increase of energy and feeling a lot brighter generally,also seems to have helped with the jetlagged feeling which I have being a shift worker.Thankyou!!

I use this product in conjunction with other Co Enzymes and it a fantastic treatment for M.E.
NADH is involved in the synthesis of adenosine triphosphate (ATP), the body's primary intracellular energy source. When NADH is oxidized in cellular energy-producing organelles called mitochondria, it forms water and energy.
This energy is preserved as ATP. Every energy-consuming reaction requires ATP, so the more NADH a cell has available, the more energy it can produce.
To keep up with the cellular demand for energy, the body continuously synthesizes NADH (a process that involves niacin, a B-complex vitamin).
Some believe M.E is nothing more than lack of chemical Adenosine Triphosphate (ATP-cellular energy), which provides power to the body. Chronic infections, stress, and other ailments tend to deplete the chemical. NADH is the chemical that jumpstarts the production of ATP in the body’s cells. NADH is known to trigger energy production through ATP generation and is also a great oxidator.

All I know is, I take one of these pills and boom! Within about 5 minutes I feel really good. I have increased energy that lasts for hours and I seem to be able to stick it out in boring staff meetings better. My concentration is definitely improved.

I have nearly finished the whole container and have not noticed any difference to my well being. Maybe it would work for other people but it has not appeared to work for me. No effects positive or negative.

Only been on the prouduct for a couple of weeks but I believe I'm seeing a noticable difference in my mood, energy level, libido, and overall wellbeing. If I continue to improve over the next two weeks I'll be rating it a 5.