Re: Buprenophine-Suboxone-

Yep. I noticed the strong feelings about it.Don't know why I called Subutex an antagonist either. I meant, as you said, a partial agonist.

I agree it's not for everyone. I think endorphin deficits and other neurochemical deficits are more common than some Docs might think they are.

They seem to have a protocol - start with SSRI's, if they don't help enough (and like the Abilify commercial says, 2 out of 3 still need something)add an NDRI or go to an SRNI, then try weird stuff like antihistamines and antiseizure meds etc.

Anything except for opiates or partial opiates. I'm not surprised about only a few being helped by bupe only. A tolerance quickly develops. I wish they'd research bupe+naloxone - Suboxone.

Like you, Suboxone helped me a lot/somewhat, unlike many other meds, and when I ran out withdrawal wasn't that bad. The last regimen the Doc had me on was Suboxone, Selegiline, and Effexor (but just because I couldn't take the FXR withdrawal and it MIGHT have been helping a little).