Type 2 diabetes can be reversed in just four months, say researchers

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Type 2 diabetes can be reversed in just four months by a combination of healthy diet, exercise and an intensive medical treatment, suggests a study.

Type 2 diabetes is a chronic condition where an individual does not produce enough insulin - the hormone that allows cells to absorb glucose in the blood - or the pancreas isn`t making insulin as efficiently as it could.

As it progresses, individuals with type 2 diabetes often need to use a healthy diet, exercise and an increasingly complex combination of medications to manage the condition.

"By using a combination of oral medications, insulin and lifestyle therapies to treat patients intensively for two to four months, we found that up to 40 percent of participants were able to stay in remission for three months after stopping diabetes medications," said study`s first author Natalia McInnes from McMaster University and Hamilton Health Sciences, in Ontario, Canada.

"The findings support the notion that Type-2 diabetes can be reversed, at least in the short term - not only with bariatric surgery, but with medical approaches," McInnes added.

For the study, the team randomly divided 83 individuals into three groups.Two of the groups received an intensive metabolic intervention, where they were provided with a personalised exercise plan and a suggested meal plan that reduced their daily calorie intake by 500 to 750 calories a day.

One group underwent the intervention for eight weeks, while the other was treated intensively for 16 weeks.

After the intervention, individuals in both groups stopped taking diabetes medications and were encouraged to continue with lifestyle changes.The two intervention groups were compared to a control group of individuals with Type-2 diabetes.

The results indicated, three months after the intervention was completed, 11 out of 27 individuals in the 16-week intervention group met HbA1C criteria for complete or partial diabetes remission, compared to four out of 28 individuals in the control group.

"The idea of reversing the disease is very appealing to individuals with diabetes. It motivates them to make significant lifestyle changes and to achieve normal glucose levels with the help of medications. This likely gives pancreas a rest and decreases fat stores in the body, which in turn improves insulin production and effectiveness," McInnes explained.

The study appeared in the Journal of Clinical Endocrinology & Metabolism.

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