What is ZYTIGA®?

ZYTIGA® (abiraterone acetate) is a prescription medicine that is used along with prednisone. ZYTIGA® is used to treat men with castration-resistant prostate cancer (prostate cancer that is resistant to medical or surgical treatments that lower testosterone) that has spread to other parts of the body.

IMPORTANT SAFETY INFORMATION

Who should not take ZYTIGA®(abiraterone acetate)?

Do not take ZYTIGA® if you are pregnant or may become pregnant. ZYTIGA® may harm your unborn baby. Women who are pregnant or who may become pregnant should not touch ZYTIGA® without protection, such as gloves.

ZYTIGA® is not for use in women or children. Keep ZYTIGA® and all medicines out of the reach of children.

Before you take ZYTIGA®, tell your healthcare provider if you:

Have heart problems

Have liver problems

Have a history of adrenal problems

Have a history of pituitary problems

Have any other medical conditions

Plan to become pregnant (See "Who should not take ZYTIGA®?")

Are breastfeeding or plan to breastfeed. It is not known if ZYTIGA® passes into your breast milk. You and your healthcare provider should decide if you will take ZYTIGA® or breastfeed. You should not do both. (See "Who should not take ZYTIGA®?")

Take any other medicines, including prescription and non-prescription medicines, vitamins, and herbal supplements. ZYTIGA® can interact with many other medicines.

If you are taking ZYTIGA®:

Take your prescribed dose of ZYTIGA® one time a day. Your healthcare provider may change your dose if needed.

Do not stop taking your prescribed dose of ZYTIGA® or prednisone without talking to your healthcare provider first.

Take ZYTIGA® on an empty stomach. Do not take ZYTIGA® with food. Taking ZYTIGA® with food may cause more of the medicine to be absorbed by the body than is needed and this may cause side effects.

No food should be eaten 2 hours before and 1 hour after taking ZYTIGA®.

Swallow ZYTIGA® tablets whole. Do not crush or chew tablets.

Take ZYTIGA® tablets with water.

Your healthcare provider will do blood tests to check for side effects.

Men who are sexually active with a pregnant woman must use a condom during and for one week after treatment with ZYTIGA®. If their sexual partner may become pregnant a condom and another form of birth control must be used during and for one week after treatment with ZYTIGA®. Talk with your healthcare provider if you have any questions about birth control.

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