Logon to the vSphere client > Inventory > Configuration > Networking > You will most likely have one Virtual Switch already configured. The aim here is to add Jumbo Frames to a new VMkernel Port by adding a new VMkernel port with Jumbo Frames.

As your VMkernel port would have IP addresses attached to it for the management network (your connection to the host), you will need to create a brand new Virtual Switch first that has no VMkernel port added to it. Call this vSwitch1.

You will need to do these next steps from the Command Line Interface on the vSphere host server itself, hit ALT F1 to access the CLI. To enable Jumbo Frames on the vSwitch run the following command. esxcfg-vswitch -m 9000 vSwitch1

You can optionally assign a VLAN tag to the VMkernel port, if you are sharing this physical NIC with other networks. The VLAN tag is specified after the -v in the example below. Here we are using vlan 10. esxcfg-vswitch -v 10 -p JumboFrames vSwitch1

Last step is to configure the IP address of the VMkernel port along with the MTU size of 9000 (Jumbo Frames). For this step, a network adaptor will need to be added for this. esxcfg-vmknic -a -i 10.1.1.1 -n 255.255.255.0 -m 9000 -p JumboFrames