For metastases, Perfusion MRI may not be as useful in predicting mean active tumor fraction (AT). Clinicians must be judicious with their use of MRP in predicting tumor recurrence and radiation necrosis
2).

While perfusion MRI is not the ideal diagnostic method for differentiating gliomarecurrence from pseudoprogression, it could improve diagnostic accuracy. Therefore, further research on combining perfusion MRI with other imaging modalities is warranted
3).