..Full investigation includes upper gastrointestinal endoscopy and ileocolonoscopy. Treatment requires multidisciplinary input as part of a clinical network led by a paediatrician with special expertise in the management of the condition...

Enteral nutrition as primary therapy in childhood Crohn's disease: control of intestinal inflammation and anabolic response

..The aim of the study was to assess if the estimated average requirements for energy for normal children (EAR) and the Schofield equation could reliably predict energy requirements in children with inactive Crohn's disease (CD)...

..4 per 100,000 in childhood. There is a paucity of data regarding outcome particularly with the increased use of early immunosuppression. This study reviews outcome at 2 years in a cohort with UC referred to a single centre...

Energy intakes of children with Crohn's disease treated with enteral nutrition as primary therapy

..Newer immunosuppressive strategies based on cytokine modulation may be helpful in children once more experience is gained from their use in adults...

Ultrasound scanning may reduce the need for barium radiology in the assessment of small-bowel Crohn's disease

A R BremnerDivision of Infection, Inflammation and Repair, Southampton University School of Medicine, Southampton, UKActa Paediatr 93:479-81. 2004

..However, the role of USS in the assessment of CD has not been fully defined. This study compared USS and barium follow-through (BaFT) in the assessment of CD...

Evidence for the role of interferon-alfa production by dendritic cells in the Th1 response in celiac disease

Antonio Di SabatinoCentre for Infectious Disease, Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London, United KingdomGastroenterology 133:1175-87. 2007