Browse our POFUT1 Proteins (POFUT1)

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Protein O-Fucosyltransferase 1 Proteins (POFUT1)

On www.antibodies-online.com are 11 Protein O-Fucosyltransferase 1 (POFUT1) Proteins from 6 different suppliers available. Additionally we are shipping POFUT1 Antibodies (67) and POFUT1 Kits (6) and many more products for this protein. A total of 93 POFUT1 products are currently listed.

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More Proteins for POFUT1 Interaction Partners

Human Protein O-Fucosyltransferase 1 (POFUT1) interaction partners

Our findings suggested that overexpression of Pofut1 and activated Notch1 (show NOTCH1 Proteins) signaling may be associated with a poor prognosis in breast cancer.

POFUT1 gene expression in gastric cancer

POFUT1, POGLUT1 (show POGLUT1 Proteins) and ADAM10 (show ADAM10 Proteins) are processing enzymes that are involved in different steps of Notch (show NOTCH1 Proteins) receptor activation in the epidermis[10]; the roles of these unique enzymes in a single pathway may explain both the overlapping and distinct clinical features of DDD (show KRT5 Proteins) and RAK (show FRK Proteins) patients

High expression of POFUT1 correlates with aggressive clinicopathological characteristics and poor prognosis of hepatocellular carcinoma patients.

Only a novel 1-bp deletion (c.246+5delG) in POFUT1 was found in a Chinese family with Dowling-Degos disease (DDD (show KRT5 Proteins)). No other novel mutation or this deletion was detected in POFUT1 in a second DDD (show KRT5 Proteins) family and a sporadic DDD (show KRT5 Proteins) case by Sanger Sequencing.

Identification of six pathogenic POFUT1 mutations in Dowling-Degos disease patients of different ethnic origin.

POFUT1 expression can contribute to cancer progression and that POFUT1 may serve as a diagnostic marker and a therapeutic target for OSCCs.

The protein product of POFUT1 plays a significant and conserved role in melanin synthesis and transport.

both wild-type and mutant Pofut1 proteins were degraded through lysosome dependent machinery. Pofut1 protein loss in the point mutant embryos caused the same phenotypes as those observed in Pofut1 null embryos

The POFUT1 binds EGF (show EGF Proteins)-like domains of the hEGF type and that the highly correlated presence of POFUT1 and fucosylatable hEGFs has accompanied animal evolution.

Loss of Pofut1 expression is associated with Muscle Aging-Related Phenotypes.

POFUT1 Protein Profile

Protein Summary

This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms.