Estimation

While MAP can only be measured directly by invasive monitoring it can be approximately estimated using a formula in which the lower (diastolic) blood pressure is doubled and added to the higher (systolic) blood pressure and that composite sum then is divided by 3 to estimate MAP. In patients with sepsis, the vasopressor dosage may be titrated based on estimated MAP.[4]

Clinical significance

It is believed that a MAP{\displaystyle MAP} that is greater than 70 mmHg is enough to sustain the organs of the average person. MAP{\displaystyle MAP} is normally between 65 and 110 mmHg.[9] MAP may be used similarly to Systolic blood pressure in monitoring and treating[clarification needed] for target blood pressure. Both have been shown advantageous targets for sepsis, trauma, stroke, intracranial bleed, and hypertensive emergencies.[10]

If the MAP{\displaystyle MAP} falls below this number for an appreciable time, vital organs will not get enough oxygen perfusion, and will become hypoxic, a condition called ischemia.