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Phase Genomics ProxiMeta Hi-C

May 22, 2017

Phase Genomics has launched ProxiMeta Hi-C, a service that employs Hi-C sequencing on metagenomic samples to obtain complete individual genomes without culturing or high molecular weight DNA extraction. ProxiMeta Hi-C is based on capturing DNA with in vivo Hi-C so sequence reads can be traced back to their cell of origin. Researchers from the University of Washington first described the approach in 2014 in G3: Genes Genomes Genetics.

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Nov 15, 2018

SoftGenetics GeneMarker Sequence Repeat Expansion Analysis

SoftGenetics has released a new application for its GeneMarker software called Sequence Repeat Expansion Analysis. The app performs repetitive calculations by converting fragment size to repeat length so users no longer have to transfer data from genotyping platforms to spreadsheets, saving time and eliminating the potential for error in making such transfers.

Nov 09, 2018

Arima Genomics Arima-HiC Platform

Arima Genomics has announced the commercial launch of its Arima-HiC sample preparation kit. The tool allows researchers to detect long-range chromatin interactions that can be used across multiple applications. Depending on the application, researchers can generate high-quality Hi-C libraries using less than 100,000 cells across rare samples in six hours, the firm said.

10x Genomics has launched a number of new products. Its Single Cell ATAC Solution enables researchers to analyze open chromatin regions in single cells for epigenomic studies. The Feature Barcoding technology enables specific biological components, such as cell surface proteins or CRISPR-mediated perturbations, to be analyzed simultaneously with gene expression in the same cell. The technology is compatible with both the single-cell gene expression and immune profiling kits. In addition, the firm has launched version three of its Single Cell Gene Expression Solution, which includes enhancements to reagents, microfluidic chips, software, and visualization tools. That kit will begin shipping in December.

Nov 08, 2018

NanoString CAR-T Characterization Panel

NanoString Technologies has announced the launch of a new gene expression panel for the molecular characterization of CAR-T cells in research, development, and manufacturing of adoptive cell therapies. According to the company, the new nCounter(R) CAR-T Characterization Panel was created in collaboration with eight academic centers and is designed for use across the entirety of the CAR-T workflow including leukapheresis, manufacturing, and post-infusion monitoring.

Hologic Panther Fusion Open Access Functionality

Hologic has introduced an Open Access functionality that will allow CLIA-certified laboratories to develop laboratory developed tests to run on its fully automated Panther Fusion platform. Labs will be able to run their LDTs simultaneously with commercially available IVD assays, and results will release automatically to laboratory information systems.

The Open Access functionality is enabled by the new myAccess software, which is designed to help laboratories create protocols, analyze data, set thresholds, and interpret results, Hologic said.

Nov 06, 2018

Biocrates Life Sciences MxP Quant 500

Biocrates Life Sciences has released its new MxP Quant 500 system. The method allows researchers to quantitatively measure a large number of different metabolites produced by intestinal bacteria, the firm said. Biocrates believes the method will provide new insights into the interaction between patients and their intestinal flora. Researchers can use the kit to determine metabolite products in blood and stool samples, including several hundreds metabolites produced by the body and substances modified by the microbiome including; choline and its degradation products, branched-chain amino acids, and secondary bile acids.

Nov 05, 2018

Qiagen DNeasy Plant Pro Kit

Qiagen has launched the DNeasy Plant Pro Kit for extraction of high-quality DNA from varied plant samples. The new kit includes bead-beating technology for significantly higher sample disruption efficiency. Plant samples often contain high levels of secondary metabolites like polysaccharides, lipids, terpenes, or polyphenols, which are difficult to remove, Qiagen noted. To address this, the DNeasy kit also includes inhibitor removal technology to clean impurities from samples and release the DNA from masking by polyphenols.

Nov 02, 2018

Vela Diagnostics Great Basin Platform

Vela Diagnostics has commercialy launched the Great Basin infectious disease diagnostic system in Europe and the US. In preparation for the launch, Vela has relisted the products with the US and Food and Drug Administration and CE-IVD under its name. Initial site placements are evaluating the firm's Stool Bacterial Pathogens Panel. The evaluation will then be followed by Great Basin's five additional assays, including the Staph ID/R Blood Culture panel, Group B Strep Test, Shiga Toxin Direct Test, Bordetella Direct Test, and the Toxigenic C. diff test. All the assays use the Great Basin Analyzer, which is designed to perform automated sample extraction and chip-based detection in a fully enclosed cartridge with integrated data analysis.

Horizon's newly developed MSI FFPE reference standards, which were developed in a collaboration between the two companies, enable validation and routine monitoring of MSI testing on the Idylla platform. The reference standard material consists of a pair of FFPE sections, positive and negative for all seven MSI markers, providing a whole-process control that closely mimics a real FFPE sample. The reference standard is manufactured under ISO13485 at Horizon.

Nov 01, 2018

Agena Bioscience Chimeric ID Panel

Agena Bioscience has launched the research-use-only Chimeric ID Panel for chimerism analysis in bone marrow engraftment monitoring studies. The SNP-based panel is designed for use with the MassArray system and is accompanied by software which calculates the composition of a post-transplant follow-up specimen in seconds and displays the results in an easy-to-interpret report, the company said.

Nov 01, 2018

Veritas Genetics myGenome Premium, myGenome Diagnostic

Veritas Genetics announced it is now offering myGenome Premium and myGenome Diagnostic services, in addition to its $999 myGenome Standard service. The premium service is priced at $1,499 (or $500 for customers of the standard service) and is for those want a more indepth analysis of their carriers status, cancer risks, and cardiovascular risks. Within the premium service, customers will receive information on more than 400 genes associated with around 20 actionable conditions and on 125 genes linked to more than 200 carrier conditions.

The $2,999 myGenome Diagnostic service ($1,999 for customers of the standard service) is for those with a personal or family history of a genetic condition, and providers interpretation of all genes known to be associated with the disease. This service is availalbe for adults and pediatric patients, and customers will also receive reports included in the standard service.

Within myGenome Standard, Veritas is also adding a new section that inlcudes "lower-impact genetic findings" associated with 15 commone diseases, for which individuals may be able to lower their risks via lifestyle changes.

Oct 31, 2018

NeuMoDx 288 and NeuMoDx 96 Molecular Systems

NeuMoDx Molecular has launched the NeuMoDx 288 Molecular System and the NeuMoDx 96 Molecular System in the US. The 288 system loads up to 288 patient samples and has been cleared by the US Food and Drug Administration, while the 96-sample instrument is registered with the FDA for lab-developed testing use. Both instruments are PCR-based and enable continuous, random-access, sample-to-results workflows for on-demand, high-throughput sample processing with an operator walkaway window of up to eight hours. The systems use the firm's proprietary NeuDry reagents which require no refrigeration and have an on-board stability of up to 60 days and room temperature shelf life of more than one year. The instrument can run NeuMoDx's growing menu of infectious disease and sexually transmitted infections assays, as well as LDTs using the company's general-purpose reagents and consumables.

Oct 31, 2018

Agilent Technologies Agilent OnePGT

Agilent Technologies has launched Agilent OnePGT, a genome-wide, next-generation sequencing solution for preimplantation genetic testing. OnePGT allows parallel detection of multiple monogenic disorders, translocations, and aneuploidies from a single biopsy, going from biopsy to a single comprehensive report in a matter of days, Agilent said. The test is run on the company's Alissa platform, allowing for automatic calling of genetic abnormalities with built-in quality control metrics and an audit trail. This solution provides fertility specialists more comprehensive PGT data in order to help them identify the most viable embryos for transfer.

Oct 31, 2018

Uromonitor Bladder Cancer Recurrence Test

Uromonitor has launched its genetic test for detecting the recurrence of bladder cancer. Also called Uromonitor, the urine-based test detects trace amounts of FGFR3 and Tert promoter mutations, which are associated with early stages of bladder cancer. Portugal's Institute of Molecular Pathology and Immunology of the University of Porto, and the Institute for Research and Innovation in Health developed the test, which is CE marked.

Oct 30, 2018

Vela Diagnostics Sentosa SQ HCV Genotyping Assay

Vela Diagnostics has launched a new version of its Sentosa SQ HCV Genotyping Assay with improved reporting and data-interpretation features. The test uses next-generation sequencing to detect HCV genotypes 1, 2, 3, 4, 5, and 6, and subtypes 1a and 1b, and to report HCV variants in clinically relevant regions of NS3, NS5A and NS5B genes to allow drug-resistance assessment. This assay offers an integrated solution from sample to result in approximately two days with hands-on time of less than 2.5 hours.