"The Vampire Diaries" (8 p.m., The CW): The Season 5 finale apparently puts some lives at risk. In other words, it's business as usual.

"The Big Bang Theory" (8 p.m., CBS): Prime time's most popular sitcom closes out its seventh season with Sheldon (Jim Parsons) taking stock of the life-altering changes going on within the gang and considering a monumental move. Does this mean he's going to shift from his regular seat on the couch?

"Grey Anatomy" (9 p.m., ABC): Have the tissues handy. In the Season 10 closer, we're forced to bid farewell to hard-driven surgeon Cristina Yang (Sandra Oh), one of TV's great characters. We'll be OK, but what about poor Meredith (Ellen Pompeo)?