This highly engaging guide for clinical researchers provides a foundation for improving skills in the understanding of ethical requirements in the design and conduct of clinical research. It includes practical information on ethical principles in clinical research, designing appropriate research studies, writing consent and assent documents, getting... more...

Considering the current interest in cellular regulation and intracellular signalling systems, it is surprising that the contribution of ADP-ribosylation reactions to the modulation of a variety of specific cell processes, in parallel with other post-translational modifications such as phosphorylation, has not been generally recognized. While it... more...

Paroxysmal Nocturnal Hemoglobinuria (PNH) has been recognized for over a century. This mysterious disease is now understood at the level of the gene and the protein. The pathophysiology is related to a class of cell surface proteins with distinctive biochemical and physical characteristics. Recently it has been acknowledged that PNH is not rare, and... more...

In the Book of Genesis, the first words God speaks to humanity are "Be fruitful and multiply." From ancient times to today, these words have been understood as a divine command to procreate. Fertility is viewed as a sign of blessedness and moral uprightness, while infertility is associated with sin and moral failing. Reconceiving Infertility explores... more...

In this new edited volume, Charles S. Bullock III collects original contributions from top political scientists to evaluate Sarah Palin and the Tea Party's role in the 2010 midterm elections. Key States, High Stake s focuses on states where Republicans had the chance to pick up Senate seats, as well as examining GOP Senate primaries if they involved... more...