The volume features current basic, clinical, and translational
research on aspects of skeletal morphogenesis and remodeling in
health and disease. Papers survey vital new insights into the
mechanisms of bone development and restructuring, including
cellular and mechanical triggers, receptors and signaling
pathways. Also covered are the effects of other physiological
systems and disease states, such as immune system inflammation,
diabetes, infection, and cancer on musculoskeletal health. Recent
findings are shaping therapeutic directions that focus on both
anti-resorptive and anabolic therapies.

Basic scientists, clinical investigators, and clinicians with
interests spanning endocrinology, physiology, cell biology,
pathology, genetics, molecular biology, rheumatology, oncology, and
other areas that relate to bone development and homeostasis will
find this a valuable resource for the most recent developments in
skeletal biology and medicine.

This volume presents manuscripts stemming from the 4th New York
Skeletal Biology and Medicine Conference, held at Mount Sinai
School of Medicine in New York City on April 27–30, 2011. The
papers included in this volume include two of the topic areas
presented at the conference; the other topic areas are included in
Skeletal Biology and Medicine I.

ACADEMY MEMBERS: Please contact the New York Academy of Sciences
directly to place your order (www.nyas.org). Members of the New
York Academy of Science receive full-text access to Annals
online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx
for more information about becoming a member.

Instructors

Permissions

To apply for permission please send your request to permissions@wiley.com with
specific details of your requirements. This should include, the Wiley title(s), and the specific portion of the content you wish to re-use
(e.g figure, table, text extract, chapter, page numbers etc), the way in which you wish to re-use it, the circulation/print run/number of people
who will have access to the content and whether this is for commercial or academic purposes. If this is a republication request please include details
of the new work in which the Wiley content will appear.