the Oncology Nurse Advisor take:

The researchers examined effects, moderators, and mediators of 12 months of exercise on HRQoL in older long-term survivors.

The study included a total of 100 men who were randomized to two groups. The exercise (EX) group had 6 months of supervised aerobic and resistance exercise followed by 6 months of a home-based maintenance program.

The physical activity (PA) group were given printed material regarding physical activity for 12 months. The participants were assessed at 6 and 12 months.

The EX group demonstrated significant benefits in global QoL, physical function, and social function compared with the PA group at 6 months.

In addition, the effects on physical function were sustained at 12 months. Moderating factors included marital status, initiation of exercise sooner after diagnosis, and previous use of bisphosphonates.

Aerobic and resistance exercise appears to have beneficial effects on health-related quality of life.

Aerobic and resistance exercise appears to have beneficial effects on HRQoL among older, long-term survivors of prostate cancer.