A spontaneous mutation leading to the formation of congenital ovarian and testicular tumors was detected in the WKY/Ztm rat strain. testes of homozygous males were reduced in both size and excess weight. This testicular malformation was linked to a lack JTP-74057 of spermatogenesis using immunohistochemical and histological staining. Our WKY-genes can contribute to the neoplastic […]