When I was on Nexium my symptoms were worse and I had side effects. I felt like I had the flu, achy and run down. I also had sore ribs and muscles. I felt as if I had just had a vigorous work out. I was on it for 6 weeks and when I quit the side effects went away. I also took Protonix but didn't have side effects from it. It wasn't helping with my symptoms so my dr. told me to stop. Right now I don't take anything. I am waiting for a second opinion.