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Say I run Linux off a USB stick.
Is this the same speed and performance as running off an SD hard drive?

Not even remotely close. Running off a USB stick is SLOW. It might be marginally better with a USB 3.0 drive in a USB 3.0 port but it will never even approach the throughput of spinning hard drive much less an SSD.

Are you a clueless Kali user? If you can't get Kali running on your own, it ain't the right distro for you.

It is designed to run the OS off a stick so that the disks can be used exclusively for data.

It is monitored and controlled by a custom web server, and responses to web requests are very slow compared to other means of storage.

Best wishes ... cheers, drl

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( Mn, 2.6.n, AMD-64 3000+, ASUS A8V Deluxe, 1 GB, SATA + IDE, Matrox G400 AGP )

Say I run Linux off a USB stick.
Is this the same speed and performance as running off an SD hard drive?

No - there are fundamental differences in the flash memory used in USB sticks and SSD drives. While USB flash used to be *very* slow, it has improved. But in general, it's only 'speedy' when writes/reads are sequential. And USB flash is not designed to last with many reads and writes over and over - it will fail much sooner than an SSD. This makes it not ideal to run an operating system (unless the OS resides primarily in memory.)