Book Description
Microdialysis is currently one of the most important in vivo sampling methods in physiology and pharmacology. It is used to determine the chemical components of the fluid in the extracellular space of tissues. The technique is now well established in neuroscience research and is used excessively in behavioral neuroscience to determine the concentrations and identities of molecules in brain tissues, and their change due to behavior, hormonal and transmitter changes in the nervous system. The book provides a detailed comprehensive overview of the technology and its applications, including application in pathology, drug development, and the application in the clinic. The authors are all well known researchers in Neuroscience and experts in the use of Microdialysis.

Organized into two parts of seven sections, the Handbook of Microdialysis critically examines recent developments in the field through a variety of chapters written by an internationally acclaimed group of authors. It is the first comprehensive handbook covering the technology of Microdialysis and its applications in Neuroscience.

* Presents microdialysis methods and interpretation including the technical aspects of microdialysis as a sampling technique followed by the analytical chemical methods
* Discusses the role of microdialysis in pharmacology, drug development and models of CNS
pathology
* Includes clinical applications of microdialysis

From the Back Cover
Microdialysis is currently one of the most important in vivo sampling methods in physiology and pharmacology. It is used to determine the chemical components of the fluid in the extracellular space of tissues. The technique is now well established in neuroscience research and is used excessively in behavioral neuroscience to determine the concentrations and identities of molecules in brain tissues, and their change due to behavior, hormonal and transmitter changes in the nervous system. The book provides a detailed comprehensive overview of the technology and its applications, including application in pathology, drug development, and the application in the clinic. The authors are all well known researchers in Neuroscience and experts in the use of Microdialysis.

Organized into two parts of seven sections, the Handbook of Microdialysis critically examines recent developments in the field through a variety of chapters written by an internationally acclaimed group of authors. It is the first comprehensive handbook covering the technology of Microdialysis and its applications in Neuroscience.

With an ever-expanding array of biomaterials and implant devices appearing in the field, this source helps surgeons assess and utilize the latest technologies to improve the reconstruction of the spine and enhance the reconstitution of diseased spinal segments. With illustrative descriptions of specific clinical scenarios, this guide helps surgeons select the best devices and materials for reconstructive procedures and considers issues in biocompatibility, biostability, and structure-function relationships for enhanced patient outcomes and mobility.
Product Details

“Nursing Care of the Pediatric Neurosurgery Patient” serves as a detailed reference for all nurses caring for children with neurosurgical problems. Staff nurses (and student nurses) working in clinics, PICU, pediatrics, operating rooms, post-anesthesia care units, emergency department and radiology will benefit from the information presented in this book. The explanations of pathophysiology, anatomy, radiodiagnostic testing and treatment options for each neurosurgical diagnosis will help them to understand the rationale behind the nursing care. Presenting symptoms and findings on neurological examination and history will enable nurses to identify normal signs. Each chapter includes information on patient and family education and will give helpful guidelines. Although there has been a need within the pediatric neurosurgery community for this type of information for years, there is no other reference available that provides this type of specific information.
Product Details

As a consequence of the enormous technological progress in and around modern neurosurgery – such as preoperative investigation of the exact individual anatomy of the patient, individual planning of the procedure, application of navigation techniques, use of endoscopes and videosurgery – approaches for intracranial microsurgical procedures have become small in comparison to historically standard neurosurgical approaches. The atlas is a continuation of the previous works “Endoscopic Anatomy for Neurosurgery” and “Keyhole Concept in Neurosurgery” presenting the operative technical description of the different keyhole approaches based on surgical anatomical examples. The approaches, strategies, indications and technical details are demonstrated by anatomical pictures, schemes, and artists illustrations. Each approach is analyzed with regard to its geometric boundaries and the topography of the target structures. The book offers a systematic overview of keyhole approaches in the daily work of a neurosurgeon.

“Neural stem cells have the capacity to generate all of the multiple cell types found in the brain and spinal cord, thus, they have the potential to repair tissue injured by trauma or disease. The Guest Editors are researchers and clinicians who have done extensive work on human neural stem cells and the regeneration of neural cells in the brain. This issue of the Neurosurgery Clinics discusses embryonic and adult neural stem cells and their role in brain tumors, neurorestoration, trauma, and stroke.
Contents: 1. Embryonic human stem cells: Present and Future; Germinal Regions in the Adult Human Brain; Astrocytes as Adult Neural Stem Cells; Identification of Human Brain Tumor Initiating Cells; BMP-Mediated Therapeutic Targeting of Brain Tumor Stem Cells; Neural Precursors and Their Role in Medulloblastomas; PDGF-Mediated Gliomagenesis and Brain Tumor Recruitment; Stem Cells as Vehicles for the Treatment of Brain Cancer; Gene Chip Analysis of Epigenetic Stem Cell Remodeling; Glial Progenitors and Demyelinating Lesions; Adult Neurogenesis and Hippocampal Memory Function; Radiation Response of Neural Precursors; Injury following trauma or stroke; Regeneration of the Injured Spinal Cord; TBI-Related Effects on Neurogenesis; Neurogenesis after stroke: effects of growth factors.

This Second Edition has been thoroughly revised to reflect recent advances in the field of percutaneous vertebroplasty. Obsolete sections have been replaced with cutting-edge material, such as an in-depth look at the latest bone cements and devices. Chapters outline spine anatomy, medical management, and patient selection. The text is enhanced by a wealth of illustrations. The addition of practical and challenging case studies furthers the focus of the previous edition by bridging the gap between theory and practice for spine interventionalists, radiologists, neuroradiologists, orthopedic surgeons, and neurosurgeons.

New to the Second Edition:

– New data on alternate routes for therapy, sacroplasty, and treating tumors

– New treatment techniques

– Updated examination of biomechanics

– New material on complications

– Inclusion of vertebroplasty and kyphoplasty cases

– Expanded presentation of ACR and SIR care standards

– New figures and color images

Non-accidental Head Injury in Young Children: Medical, Legal and Social Responses by Cathy Cobley, Tom Sanders

Neuro-Oncology is the first volume in the second edition of the highly regarded Neurosurgical Operative Atlas series first published by the American Association of Neurological Surgeons. It provides an accessible, step-by-step guide to the newest approaches for managing brain, skull base, and spinal tumors. Organized into concise sections according to anatomical location, type of tumor, and surgical approach, this book enables the reader to rapidly review key concepts in preparation for surgery. In each chapter the author describes the case selection, the operative indications and contraindications, special points concerning anesthesia, the various operative approaches available, and the possible complications during and after surgery. Concise, yet thorough, this text will be an invaluable reference for both beginning and established neurosurgeons. Highlights: Covers the full range of neuro-oncological problems, including sellar and parasellar tumors, intraventricular tumors, spine and peripheral nerve tumors, malignant brain tumors, meningiomas, and posterior fossa tumors Features more than 500 high-quality illustrations that supplement descriptions of each step of the procedures, providing an indispensable visual aid to managing complex clinical situations

Evidence-Based Neurosurgery Haines / Walters

ISBN: 1588903915

Evidence-Based Neurosurgery: An Introduction will teach the practitioner to employ evidence-based approaches to common problems in neurosurgery. The book begins with a review of the concepts and techniques involved in the practice of evidence-based medicine, including the basics of critical analysis using methodologically rigorous evidence-synthesis techniques. The second part of the text provides useful examples of the use of this critical analysis for common clinical situations, such as stent placement, managing infection, metastases, craniocerebral trauma, cervical spine trauma, and more. The book covers all phases of clinical practice, from patient assessment, to diagnosis, to prognosis, and treatment, helping you address such questions as: How do you reliably determine the characteristics of the individual patient’s condition? What is the likely course of the disease? How do you determine what interventions are likely to have a positive impact? Does the intervention work under certain specified circumstances? Evidence-Based Neurosurgery is an invitation to apply the rigorous methods of evidence-based medicine to improve your practice of neurosurgery.

Recent advances in skull base surgery are revolutionizing the field. Besides the critical location issue, the major problem in lateral skull base surgery is understanding the complex relations between the different structures of the region, requiring a deep knowledge of anatomy. Here is an enlarged new edition of the first full-color atlas to present a variety of step-by-step approaches to the temporal bone and lateral skull base. Each sequence is illustrated with images of cadaver specimens that show the extradural and intradural parts, including cerebral vessels and nerves. A unique demonstration of three-dimensional anatomy of the surgical field as seen by the surgeon adds to the realistic quality of the book. Indications, pearls, and pitfalls, gained through the authors’ actual clinical experience, complete this masterful work.