Scleroderma (hepatobiliary manifestations)

Hepatobiliary manifestations of scleroderma are only present symptomatically in a minority of patients. Around 2.5% of patients with scleroderma develop clinically significant primary biliary cirrhosis, however, antibody studies suggest that subclinical disease may be present in as many as 15% of patients.

For a general discussion of scleroderma, please refer to the parent article: scleroderma.