Is it true that tramadol will cancel out the effect of some drugs if you take it before?

In brief:
No, but...

Tramadol is a weak opioid-like analgesic that is infamous for its interactions with SSRIs (anti-depressants) and for causing seizures.

Both your pharmacist and PCP should be well-versed in this possibility. You may want to discuss this particularly with your pharmacist, by reviewing your current medication list for the potential of interactions with tramadol.

In brief:
No, but...

Tramadol is a weak opioid-like analgesic that is infamous for its interactions with SSRIs (anti-depressants) and for causing seizures.

Both your pharmacist and PCP should be well-versed in this possibility. You may want to discuss this particularly with your pharmacist, by reviewing your current medication list for the potential of interactions with tramadol.
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