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Party- and Date hubs

Protein interaction network is a graph where protein-protein interactions are presented. Analog is a social network where human-human interactions are presented.

For proteins we can use some measured activity information (gene expression activity) that we have collected in a database and web-tool MEM http://biit.cs.ut.ee/mem/
Based on these data the goal is to analyse protein interaction network and find party- and date hubs from there.

The yeast interactome exhibits organized modularity where a small proportion of proteins – the 'hubs' – interact with many partners. These hubs fall into one of two categories: 'party' hubs, which interact with most of their partners simultaneously, and 'date' hubs, which bind different partners at different locations and times.