Outside the office, Dr.Shu dedicates his time to community activism. After forming the Minnesota Chinese Physician Association (AMCP) in 2003, he led its members and community volunteers in establishing the Minnesota Chinese Health Center (MCHC), a free clinic for disadvantaged Chinese in the Twin Cities. He is also publisher of Minnesota Times, the most widely circulated Chinese newspaper in Minnesota.

In the recent years, Dr.Shu has regularly participated in an international mission organized by NSVI to the Philippines and Haiti as part of a global effort to control the population in the developing countries with rapid population growth. In 2017, he became a founding president of Medical Volunteers International (MVI), a new non-profit organization dedicating the medical missions in the poorest countries around world.