Datasheet Extract

MORF4L2 is a member of the mortality factor (MORF) family of transcriptional regulator that is involved in cell growth, regulation and senescence. This protein localizes to the nucleus, and it has a protein kinase C phosphorylation site as well as a tyrosine phosphorylation site. It interacts with the Rb tumor suppressor through its helix-loop-helix and leucine zipper regions. It also has histone deacetylase activity and can either repress or promote the activity of the B-Myb promoter depending on the tissue. Recombinant human MORF4L2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Concentration

0.5 mg/ml

Storage

Store at -80C. Avoid freeze-thaw cycles.

Format

Buffer System:

Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT

State:

Purified

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