Two ampoules, hermitically sealed vials, of anti-cholera vaccine, mounted on board for display, 1892 with suggested reading materials on the topic of cholera vaccination

The first cholera vaccine was created by Waldemar Mordecai Wolfe Haffkine (1860-1930), a Russian bacteriologist, in July 1892 – shortly before these examples were produced. Haffkine was able to create a vaccine as the bacteria causing cholera had already been isolated by Robert Koch in 1883.