Alpha-internexin is a, 66kD, type IV intermediate filament protein(1) that is expressed in neurons during development of the peripheral and central nervous systems, as well as in a few neurons of the adult central nervous system.(2) Recent studies have demonstrated that during neuronal development, alpha-internexin replaces type VI nestin and type III vimentin intermediate filament proteins.(3) Clinical studies have also demonstrated that alpha-internexin may play a role in the development of neuronal polarity.(4)

Catalog #

I8442-74A

Applications

Suitable for use in ELISA, Western Blot, Immunoflourescence and Immunohistochemistry. Other applications not tested.

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.