Prognosis: Edelman, who has been Tom Brady's favorite receiver over the past four years, will miss the season. He suffered the injury while planting on the turf at Ford Field in Detroit after a reception Friday night. The Patriots are well-positioned in terms of wide receiver depth, with Danny Amendola, Chris Hogan, Brandin Cooks and Malcolm Mitchell ready to take more snaps. But Brady will greatly miss the receiver who has accounted for a team-high 195 first-down receptions since the start of the 2013 season. (That figure is tied for No. 12 among all NFL receivers during that span.)

Prognosis: The NFL's concussion protocol is not one-size-fits-all, so it's impossible to know how long it will take Taylor to pass the tests that are required before he can return. Taylor suffered the injury Saturday night when he fell hard on the back of his head during a sack. Every concussion is different, and there have been enough recent examples of players missing weeks -- and sometimes months -- for Taylor to merit inclusion on this list. At the moment, the backup is rookie Nathan Peterman, a fifth-round draft pick from Pittsburgh.

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Prognosis: [UPDATED] After some initial optimism about a midseason return, the Chiefs said Sunday that Ware is likely to need season-ending surgery. He suffered the injury after making a reception Friday night, and for now it appears that rookie Kareem Hunt -- a third-round draft pick from Toledo -- will replace Ware as the feature back.

Prognosis: [UPDATE] Petty is not expected to miss much time and could play in the Jets' preseason finale Thursday night, according to ESPN's Adam Schefter. That is the best-case outcome for an injury that appeared more serious when he suffered it Saturday night. At the time, Petty couldn't put weight on the leg and told reporters that the knee wasn't stable. Regardless, the episode probably eliminates any chance Petty had to compete with Josh McCown and Christian Hackenberg for the starting job.

Prognosis: [UPDATED] The injury will take eight weeks to recover from, according to ESPN's Todd Archer. Initial fears of a torn ACL, which would have been season-ending, appear unfounded. Hitchens was set to serve as the starting middle linebacker and had started 36 of 48 games since the Cowboys made him a fourth-round draft choice in 2014. In his absence, the Cowboys could shift Sean Lee or Jaylon Smith to middle linebacker.

Prognosis: There has been no official (or reported) diagnosis, but the Bears' medical staff immediately placed an air cast over Meredith's knee and sent him to the locker room aboard a cart. The air cast usually indicates an obvious and serious injury. Meredith was the Bears' leading receiver in 2016 and was expected to be one of their top targets this season, as well.

In addition to the Week 3 injuries, here is an update on the players we've highlighted in our Week 1 and Week 2 injury reports: