..The goal of this study is to determine the extent of polymorphism in pfhrp2 among Senegal, Mali and Uganda parasite populations, and discuss the implications of these findings on the utility of RDTs that are based on HRP2 detection...

..Long non-coding RNAs (lncRNAs) have recently emerged as a new paradigm in epigenetic remodeling. We therefore set out to investigate putative roles for lncRNAs in P. falciparum transcriptional regulation...

Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum

..We provide an initial map of genetic diversity in P. falciparum and demonstrate its potential utility in identifying genes subject to recent natural selection and in understanding the population genetics of this parasite...

Genetic surveillance detects both clonal and epidemic transmission of malaria following enhanced intervention in Senegal

Rachel DanielsDepartment of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, United States of AmericaPLoS ONE 8:e60780. 2013

..Our results imply that genetic surveillance can be used to evaluate the effectiveness of disease control strategies and assist a rational global malaria eradication campaign...

..We also found that the gene encoding acyl-CoA binding protein has expanded and diversified in P. falciparum. We have described a new class of subtelomeric gene family with a unique capacity for diversity in P. falciparum...

..This approach will enable efficient genome sequencing of pathogens from clinical samples, as well as sequencing of endosymbiotic organisms such as Wolbachia that live inside diverse metazoan phyla...

Low-complexity regions in Plasmodium falciparum: missing links in the evolution of an extreme genome

..We discuss how the discovery of these distinct species of PfLCRs helps to resolve previous contradictory studies on LCRs in malaria and contributes to our understanding of the evolution of the of the parasite's unusual genome...

An adjustable gas-mixing device to increase feasibility of in vitro culture of Plasmodium falciparum parasites in the field

Amy K BeiDepartment of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, United States of America Laboratory of Bacteriology and Virology, Faculty of Medicine and Pharmacy, Cheikh Anta Diop University, Dakar, SenegalPLoS ONE 9:e90928. 2014

..This adjustable gas-mixing device will dramatically improve the feasibility of in vitro culture of Plasmodium falciparum parasites in malaria endemic countries given its numerous advantages. ..

Excess polymorphisms in genes for membrane proteins in Plasmodium falciparum