STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Mfla_2340

Hypothetical protein (276 aa)

Predicted Functional Partners:

Mfla_2341

Biopolymer transport protein ExbD/TolR (128 aa)

0.883

Mfla_2342

MotA/TolQ/ExbB proton channel (224 aa)

0.875

ruvB

Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (345 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

Mfla_0684

Mfla_1897

Mfla_0684

Mfla_1897

Hypothetical protein

Hypothetical protein

0.576

Mfla_0684

Mfla_2340

Mfla_0684

Mfla_2340

Hypothetical protein

Hypothetical protein

0.660

Mfla_1897

Mfla_0684

Mfla_1897

Mfla_0684

Hypothetical protein

Hypothetical protein

0.576

Mfla_1897

Mfla_2292

Mfla_1897

Mfla_2292

Hypothetical protein

Glycosyl transferase family protein

0.579

Mfla_1897

Mfla_2340

Mfla_1897

Mfla_2340

Hypothetical protein

Hypothetical protein

0.584

Mfla_2292

Mfla_1897

Mfla_2292

Mfla_1897

Glycosyl transferase family protein

Hypothetical protein

0.579

Mfla_2292

Mfla_2340

Mfla_2292

Mfla_2340

Glycosyl transferase family protein

Hypothetical protein

0.600

Mfla_2337

Mfla_2338

Mfla_2337

Mfla_2338

Tetratricopeptide region

OmpA/MotB

0.953

Mfla_2337

Mfla_2340

Mfla_2337

Mfla_2340

Tetratricopeptide region

Hypothetical protein

0.643

Mfla_2337

Mfla_2341

Mfla_2337

Mfla_2341

Tetratricopeptide region

Biopolymer transport protein ExbD/TolR

0.613

Mfla_2337

Mfla_2342

Mfla_2337

Mfla_2342

Tetratricopeptide region

MotA/TolQ/ExbB proton channel

0.768

Mfla_2337

Mfla_2343

Mfla_2337

Mfla_2343

Tetratricopeptide region

4-hydroxybenzoyl-CoA thioesterase

0.579

Mfla_2337

ruvB

Mfla_2337

Mfla_2344

Tetratricopeptide region

Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing

0.567

Mfla_2337

tolB

Mfla_2337

Mfla_2339

Tetratricopeptide region

TolB-like protein; Involved in the TonB-independent uptake of proteins

0.922

Mfla_2338

Mfla_2337

Mfla_2338

Mfla_2337

OmpA/MotB

Tetratricopeptide region

0.953

Mfla_2338

Mfla_2340

Mfla_2338

Mfla_2340

OmpA/MotB

Hypothetical protein

0.582

Mfla_2338

Mfla_2341

Mfla_2338

Mfla_2341

OmpA/MotB

Biopolymer transport protein ExbD/TolR

0.740

Mfla_2338

Mfla_2342

Mfla_2338

Mfla_2342

OmpA/MotB

MotA/TolQ/ExbB proton channel

0.947

Mfla_2338

Mfla_2343

Mfla_2338

Mfla_2343

OmpA/MotB

4-hydroxybenzoyl-CoA thioesterase

0.674

Mfla_2338

ruvB

Mfla_2338

Mfla_2344

OmpA/MotB

Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing

0.567

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: