Based on the results of the database search, 27 cases were retrieved from the University of Pittsburgh Medical Center archives for the study: 12 cases of ductal CMBC (44%), which included 11 cases with morphologies not otherwise specified and 1 case of basal phenotype; 11 cases of SGC (41%), which included 5 cases of EC, 3 cases of porocarcinoma (PC), and 3 cases of microcystic adnexal carcinoma (MAC); and 4 additional, randomly selected cases (15%), which included 2 primary cutaneous adnexal benign neoplasms (a poroma and an apocrine adenoma) and 2 cases of PBC.

Cases where significant diagnostic differences were noticed included a suspicious Kaposi sarcoma (case 16), finally reevaluated as a dermatofibroma; an invasive squamous cell carcinoma of the head diagnosed as eccrine poroma (case 21) on final microscopy; and a suspicious low-grade soft tissue sarcoma diagnosed as angioleiomyoma (case 22), which was confirmed with the help of immunohistochemical staining.

The same in situ HPV DNA probes were performed using the same technique on 3 eccrine hydrocystomas, 3 eccrine syringomas, 2 eccrine poromas, and 3 apocrine hydrocystomas; none showed any positive staining.

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