A human infecting coronavirus (viral pneumonia) called 2019 novel coronavirus, 2019-nCoV (COVID-19) was found in the city of Wuhan, Hubei province of China on December 2019.

The 2019-nCoV shares an 87% identity to the 2 bat-derived severe acute respiratory syndrome 2018 SARS-CoV-2 located in Zhoushan of eastern China. 2019-nCoV (SARS-CoV-2) has an analogous receptor-BD-structure to that of 2018 SARS-CoV, even though there is a.a. diversity, thus the 2019-nCoV might bind to ACE2 receptor protein (angiotensin-converting enzyme 2) in humans.

RSCU analysis proposes that the 2019-nCoV is a recombinant within the viral spike glycoprotein between the bat coronavirus and an unknown coronavirus.

The E. coli derived recombinant protein contains the Coronavirus 2019 full-length nucleoprotein: Gene bank- MN908947, fused to His tag at C-terminal and having a M.W. Of 48 kDa as appears on SDS-PAGE.