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The Cochrane Database of Systematic Reviews is considered the gold standard for
evidence-based medicine. Essential Evidence Plus includes the latest and most
up-to-date summaries of systematic reviews from the Cochrane Library, which are
the most rigorous and reliable evaluations of medical therapies available. You’ll
find summarized evaluations of the world’s best literature on the effectiveness of
therapy for 3,300+ clinical problems.

Selective serotonin reuptake inhibitors for premenstrual syndromeCochrane Systematic Reviews, 6-Jun-2013Premenstrual syndrome (PMS) is a common cause of physical, psychological and social problems in women of reproductive age. The key characteristic of PMS is the timing of symptoms, which occur only during the two weeks leading up to menstruation (the lutea

Selective versus routine use of episiotomy for vaginal birthCochrane Systematic Reviews, 8-Feb-2017Some clinicians believe that routine episiotomy, a surgical cut of the vagina and perineum, will prevent serious tears during childbirth. On the other hand, an episiotomy guarantees perineal trauma and sutures.

Selegiline for Alzheimer's diseaseCochrane Systematic Reviews, 12-May-2008Alzheimer's disease is the most common cause of dementia in older people accounting for some 60% of cases with late-onset cognitive deterioration. It is now thought that several neurotransmitter dysfunctions are involved from an early stage in the pathoge

Selenium for preventing cancerCochrane Systematic Reviews, 22-Jan-2018This review is the third update of the Cochrane review "Selenium for preventing cancer". Selenium is a naturally occurring element with both nutritional and toxicological properties. Higher selenium exposure and selenium supplements have been suggested to

Selenium supplementation for asthmaCochrane Systematic Reviews, 29-Sep-2008Selenium deficiency may be important in chronic asthma. Observational studies have demonstrated that patients with chronic asthma may have lower levels of selenium than their control. Nevertheless, selenium supplementation has not been recommended with dr

Selenium supplementation for critically ill adultsCochrane Systematic Reviews, 22-Apr-2016Selenium is a trace mineral essential to health and has an important role in immunity, defence against tissue damage and thyroid function. Improving selenium status could help protect against overwhelming tissue damage and infection in critically ill adul

Self management programmes for quality of life in people with strokeCochrane Systematic Reviews, 18-Aug-2016Stroke results from an acute lack of blood supply to the brain and becomes a chronic health condition for millions of survivors around the world. Self management can offer stroke survivors a pathway to promote their recovery. Self management programmes fo

Self-management education for cystic fibrosisCochrane Systematic Reviews, 29-Jun-2017Self-management education may help patients with cystic fibrosis and their families to choose, monitor and adjust treatment requirements for their illness, and also to manage the effects of illness on their lives. Although self-management education interv

Self-management education programmes for osteoarthritisCochrane Systematic Reviews, 10-Jan-2014Self-management education programmes are complex interventions specifically targeted at patient education and behaviour modification. They are designed to encourage people with chronic disease to take an active self-management role to supplement medical c

Self-management for bronchiectasisCochrane Systematic Reviews, 5-Feb-2018Bronchiectasis is a long term respiratory condition with an increasing rate of diagnosis. It is associated with persistent symptoms, repeated infective exacerbations, and reduced quality of life, imposing a burden on individuals and healthcare systems. Th

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