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ARFGAP3 Antibody Summary

Immunogen

The immunogen recognized by this antibody maps to a region between residue 466 and 516 of human ADP-ribosylation factor GTPase activating protein 3 using the numbering given in entry NP_055385.2 (GeneID 26286).

Isotype

IgG

Clonality

Polyclonal

Host

Rabbit

Gene

ARFGAP3

Purity

Immunogen affinity purified

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Packaging, Storage & Formulations

Alternate Names for ARFGAP3 Antibody

ADP-ribosylation factor GTPase activating protein 1

ADP-ribosylation factor GTPase activating protein 3

ADP-ribosylation factor GTPase-activating protein 3

ARF GAP 3

ARFGAP1

FLJ45618

Background

The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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