Methods: We reviewed 120 inpatients from 2010-2014 with AIS and a CTP from the acute setting. We used the automated Olea Sphere software to generate perfusion maps with oscillation index singular value decomposition (oSVD) and Bayesian probabilistic deconvolution. We used the manual OsiriX software to draw regions-of-interest delineating the stroke core on cerebral blood volume (CBV) and penumbra on cerebral blood flow (CBF) maps of the original CTP. For Bayesian analysis we defined stroke core as relative CBF2 seconds, and penumbra as relative mean transit time >135%. For oSVD we defined stroke core as relative CBF2 seconds, and penumbra as absolute Tmax >6 seconds. We compared techniques with a Pearson correlation coefficient and linear regression.