because of imaging up to 50% or more can be normotensive and asymptomatic ( 6 ). With the increasing number of high-resolution imaging procedures, a considerable proportion of PPGLs are now being discovered incidentally ( 7 ). As around 3–7% of

Introduction
Thyroid nodules are an increasingly common finding during imaging examinations of the neck, but only a small proportion of these lesions ultimately prove to be malignant ( 1 ). Fine-needle aspiration (FNA) biopsy plays a major

Mubashir Mulla and Klaus-Martin Schulte

thyroglobulin in needle washout (11) . Although this method is useful, it does improve sensitivity of US. A number of studies have reported the ‘usefulness’ and ‘diagnostic accuracy’ of US and other imaging modalities, namely computerised tomography (CT

regular surveillance imaging, there is no clear consensus regarding the optimal modality or frequency. The situation is even less clear in paediatric SDHB carriers due to the paucity of robust data, highlighted in a recent review ( 9 ). Since the

, magnetic resonance imaging (MRI) technology has a high precision and is observer independent during the imaging procedure (3) . Holter monitor studies have in general demonstrated increased heart rate (HR), and three studies demonstrate increased HR in

diagnosis and prognosis of neoplastic lesions ( 3 ). Computerized image analysis is an objective and highly reproducible tool in daily practice and has proven to be a promising resource for assessing thyroid lesions. More widely used for assessing