Try unpacking the music files from the Wyrmstooth BSA. Unfortunately there's a bug in the Skyrim game engine that causes a crash if it cannot read a sound file. I've solved the issue on a vanilla build by recompressing the BSA file with BSAOpt but this behaviour may change on a heavily modded system.

Right, I've unloaded all my mods except the unofficial patches and skyui. I'm running the ENBseries antifreeze patch, as well as SKSE. I've unpacked the audio files, and still the game crashes when I try to set sail to Wyrmstooth. I get about three seconds of the load screen, and then CTD.

I'm giving up on this mod until it's fixed. It looks like a lot of fun, but it seems that for me to play it I would have to completely redownload and install Skyrim and not install any mods, which is too much of a nightmare to go through for any one mod. Good luck to everyone else.

To fix this issue i had only to download the mod from skyrim nexus and install it over the steam version. Just overwhrite the old files if the Nexus mod manager asks. Here is the link for the mod on skyrim nexus.