The building will consist of the Thompson Hotel, and The Arts Residences, condominiums and penthouses, perched above the hotel on levels 12-19. The high rise includes 66 condominiums, five two-story penthouses and 167 premium hotel rooms.

San Antonio's skyline to be filled with $116 million hotel-condominium by the next two years.

Media: Courtesy Kuper Sotheby's International Realty

Both hotel guests and building residents will be able to use the 24-hour room service or dine at the hotel's restaurant, with a renowned chef who has yet to be disclosed.

"The vibe is some place you want to hangout," Dupre said of the hotel. "It's luxurious without the stuffiness."