Photo SpecialTom & Penelope: The Romance Ends

After three years as a couple – with a great deal of time spent apart on film sets – Tom Cruise and Penelope Cruz have called it quits. "They broke up at the end of January and it's amicable," Lee Anne DeVette, Cruise's sister and publicist, tells PEOPLE. Take a look back at highlights of the couple's romance.

A Kiss to Remember

In early January, just weeks before breaking up, Cruise and Cruz shared a passionate moment outside a Rome restaurant. "I'm very, very happy with my relationship," he told PEOPLE just six months earlier. But, he added, "There's no engagement."