Skin & Hair

Are you developing new active substances or BioActives? Are you mixing new formulas for skin creams or cosmetic skin products?

Your skin creams, cosmetic products and active substances should ideally have a positive effect on the skin.

Do you want to be able to prove, measure and visualise the effects and benefits of your products three-dimensionally? Do you see this ability as a help, benefit or even a sales argument?

Together we can measure the following skin parameters:

Fat distribution in the skin: Visualise fats in the stratum corneum and analyse them in 3D

Skin roughness: Distribution, depth and shape of the skin’s surface and wrinkles using 3D reconstruction

Skin hydration: by taking volume measurements of the skin cells

Artefact-free cryopreparation of the first 150µm: this enables follow-up experiments under conditions that are as close as possible to the original physiological condition of the skin structures

Network of blood capillaries: The capillarisation of dermal papillae is a parameter for skin youthfulness. Together with da-cons you can visualise blood capillaries using light sheet microscopy. We use algorithms to identify and measure blood vessels in the volume data set.

Nerve structure: We use light sheet microscopy to visualise the network of nerves across several cubic millimetres of skin. We can also apply our analyses to the data. Demonstrate the effects that your product has on nerves using images of neurodermatitic skin cells that show the nerve structure.

Sebaceous glands: 3D microscopy and special software designed to handle large data sets allow you to visualise entire sebaceous glands without needing to use a microtome

Hair follicles and rete ridges: In the near future, light sheet microscopy will allow you to investigate the effects of your formulas in 3D.

Are you developing a new hair produtct?

Conduct automated analyses of the knot tests results with da-cons.

If you knot a human hair, the hair cuticle cells will stick out from the hair’s surface wherever the hair has been bent round to make the knot. For healthy hair, this happens to 10% - 20% of the cuticle cells, but for damaged hair this figure increases to 80%. Are you interested in showing the effect of your products on the hair cuticle cells across a large number of experiments? da-cons can help you to automate and analyse the tests. We can even conduct the entire test for you.