Figure 2.

An illustration of DNA supercoiling domains in the E. coli chromosome. This is a cartoon of the chromosome; in real life there are perhaps as
many as 400 different domains. Plectonemic (unrestrained) and toroidal (restrained,
for example by wrapping around a protein) supercoiling is indicated. Curved DNA tends
to be localized at the tips of supercoils. The illustration is modified with permission
from [23].