GO curators for mouse genes have assigned the following annotations to the gene product of Rdh12. (This text reflects annotations as of Thursday, July 24, 2014.) Summary from NCBI RefSeq

[Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3). [provided by RefSeq, Jul 2008]Summary text based on GO annotations supported by experimental evidence in other organisms

From comparative sequence analysis (see table for details), MGI curators have determined that the gene product of Rdh12: