The plot

Primatologist Davis Okoye has cared for an intelligent, albino silverback gorilla named George since its birth. However, a genetic experiment turns the gentle George into a raging gigantic creature. A wolf and a crocodile have also undergone similar changes. As the three creatures go on a rampage across North America, fighting each other for supremacy, Okoye races against time with a discredited genetic engineer to secure an antidote and save George.