Fusion

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Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PBAL39_00165

Thioredoxin family protein (391 aa)

Predicted Functional Partners:

PBAL39_05898

Peptide-methionine (S)-S-oxide reductase ; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (326 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 annotation

node2 annotation

score

PBAL39_00165

PBAL39_00170

Thioredoxin family protein

Uncharacterized protein

0.859

PBAL39_00165

PBAL39_02102

Thioredoxin family protein

Glutamate synthase, large subunit

0.904

PBAL39_00165

PBAL39_05898

Thioredoxin family protein

Peptide-methionine (S)-S-oxide reductase ; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine

0.951

PBAL39_00165

PBAL39_11722

Thioredoxin family protein

Peroxiredoxin

0.864

PBAL39_00165

PBAL39_16489

Thioredoxin family protein

Thioredoxin reductase carring response regulator receiver domain

0.852

PBAL39_00165

PBAL39_16961

Thioredoxin family protein

FAD-dependent pyridine nucleotide-disulphide oxidoreductase

0.852

PBAL39_00165

PBAL39_19015

Thioredoxin family protein

Alkyl hydroperoxide reductase, F52a subunit

0.852

PBAL39_00165

PBAL39_19310

Thioredoxin family protein

Peroxiredoxin

0.864

PBAL39_00165

PBAL39_24535

Thioredoxin family protein

Ferredoxin--NADP reductase

0.852

PBAL39_00165

PBAL39_25055

Thioredoxin family protein

Thioredoxin-disulfide reductase

0.852

PBAL39_00170

PBAL39_00165

Uncharacterized protein

Thioredoxin family protein

0.859

PBAL39_02102

PBAL39_00165

Glutamate synthase, large subunit

Thioredoxin family protein

0.904

PBAL39_02102

PBAL39_16489

Glutamate synthase, large subunit

Thioredoxin reductase carring response regulator receiver domain

0.502

PBAL39_02102

PBAL39_16961

Glutamate synthase, large subunit

FAD-dependent pyridine nucleotide-disulphide oxidoreductase

0.502

PBAL39_02102

PBAL39_19015

Glutamate synthase, large subunit

Alkyl hydroperoxide reductase, F52a subunit

0.502

PBAL39_02102

PBAL39_24535

Glutamate synthase, large subunit

Ferredoxin--NADP reductase

0.502

PBAL39_02102

PBAL39_25055

Glutamate synthase, large subunit

Thioredoxin-disulfide reductase

0.502

PBAL39_05898

PBAL39_00165

Peptide-methionine (S)-S-oxide reductase ; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine

Thioredoxin family protein

0.951

PBAL39_05898

PBAL39_11722

Peptide-methionine (S)-S-oxide reductase ; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine

Peroxiredoxin

0.456

PBAL39_05898

PBAL39_16489

Peptide-methionine (S)-S-oxide reductase ; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine

Thioredoxin reductase carring response regulator receiver domain

0.634

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)

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Statistical background

For the above enrichment analysis, the following statistical background is assumed: