2017年8月10日星期四

Treatment of Recurrent CKD After Kidney Transplantation

Kidney Transplantation is the last choice for many patients with chronic
Kidney Disease. However, a large number of patients suffer from the recurrent
CKD after kidney transplantation.
Why Recurrent CKD happens after Kidney Transplant?
Most patients with CKD usually only think it is the kidney damage which
affects their life. However, it is only a part of the fact. Yes, the kidney
damage causes many other organs damaged, causing various symptoms and
complications, such as cardiovascular disease, high blood pressure, liver
failure etc. However, kidney damage is far away from the underlying cause.
Actually, more than 95% kidney diseases is caused by immune disorder. In
normal condition, each of us have a group of natural immune system. It works to
protect our health by releasing antibodies to kill the bacteria outside.
However, in people with immune disorder, the immune system fails to release
enough or functional antibodies. As a result, the antibodies form into a new
material called immune complex with the bacteria.
The immune complex is harmful for people and it can flow into any where of
the body with the carriage of blood. Once it deposits in the kidneys, it will
cause inflammations here, causing kidney damages. Thereby, we say if you only
aims to reverse the kidney damage with Kidney Transplant or other treatments,
CKD is more likely to come back sooner or later.
How to prevent recurrent CKD after Kidney Transplant?
As mentioned above, only dealing with the kidney damage, such as Kidney
Transplant, is not enough to prevent the relapse of CKD. To deal with the immune
disorder will be another key.
Immunotherapy is suggested for it helps rebuild the immune system and use the
immune system to prevent the deposition of immune complex in the kidneys. In
this way, the kidney damage relapse will be reversed from the root .