Lupus

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Transcript of Lupus

Pons-Estel, Guillermo J., MD, Graciela S. Alarcon, MD, Lacie Scofield, MSPH, Leslie Reinlib, PhD, and Glinda S. Cooper, PhD. "Understanding the Epidemiology and Progression of Systemic Lupus Erythematosus." PubMed Central. National Institutes of Health, 10 Jan. 2009. Web. 15 Feb. 2013.What is Lupus?EpidemiologySymptoms and DiagnosisNormal PhysiologyPathophysiologyTreatment and PreventionImmune SystemRaceSystemic lupus erythematosus, the most common form of lupus, is 2-4 times more frequent in non-white populations and is most prevalent in African American, Asian and Hispanic populations. GenderLupus tends to be much more frequent in women opposed to men. However, cases in men are more likely to be more aggressive and severe. AgeIn women, there is a very large age disparity in which there is a risk to be diagnosed with Lupus. In men, an increased risk of Lupus occurs in older ages as opposed to women. Other factors:Researchers have found that there is an increased risk if first degree relatives have had Lupus.Protects the body against viruses, germs, and bacteriaLymphoid organs contain a great deal of white blood cells and lymphocytes (T-cells and B-cells)B-cells make antibodies that work against the "foreign invaders"T-cells control immune responses or they fight directly against cells (i.e. cancer cells)FatiguefeverJoint StiffnessButterfly- shaped rash Cheeks and bridge of nose Malar rashSkin lesions Raynaud's phenomenonfingers or toes that turn blue or whiteShortness of breathchest paindry eyesheadaches, confusion, memory loss Pregnant women can have miscarriage.There is no cure for SLE. The goal of treatment is to control the symptoms.