A Literature Review of Indapamide (SR) Preparations

Abstract:

The theoretical results of almost 970 published papers which were collected from
different journals are reported in this work. The analysis was carried out at the research
laboratory of East West University, Dhaka and data were represented to get the vital idea
about the previous work and the possibilities of further work on this matter and different
evaluations were performed in this research. A lot of study was done about indapamide
sustained release form and collected information about the pharmacology, release profile,
action of drugs, side effects and also about another important parameters.
The main intension of literature review of indapamide was to set the work pattern for the
research. It was tried to get some ideas about the work from different journals and the
websites. The work schedule was made after the evaluations of the literatures and the
experiences were implemented on the further research process. The data of the research
helped a lot to get the general information's and wok. From the study I got the
relationship between the increase in blood pressure and the incidence of cardiovascular
disease is well recognized today. Studies have shown that more attention should be paid
to systolic blood pressure (SBP) in relation to cardiovascular risk and that therapeutic
interventions should preferably focus on reducing SBP. The antihypertensive efficacy of
indapamide 1.5 mg sllstained release (indapamide SR), a low-dose thiazide-type diuretic,
is assessed on SBP. The treatment with indapamide SR resulted in a better or equivalent
control of SBP than treatment with a standard dose of a true thiazide diuretic
(hydrochlorothiazide), a calcium channel blocker (amlodipine), and an angiotensinconverting
enzyme inhibitor (enalapril). In conclusion, indapamide SR is very effective
in lowering SBP- a major . independent cardiovascular risk factor-notably in
h: pertensive high-risk patients with L VH, the elderly and diabetics, when compared to
major antihypertensive treatments. This SBP-lowering effect is maintained over the long
term.

Description:

This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh.