17 individuals had aortic diameters above expected levels. A positive correlation was found between systolic BP (r=0.36; P=0.001) and age, but not weight or BMI. HR correlated negatively to VO2max (r=0.22; P=0.038). We found no correlation between BP and aortic diameters or age and aortic diameters. There was however a significant increase in aortic diameters in TS with karyotype 45,X compared to others (P<0.02) and in TS with bicuspid aortic valves (P<0.02).

Conclusion: Hypertension is common in TS, affecting more than 50% of the study group, and subjects on antihypertensive treatment were insufficiently treated. Aortic dimensions are larger in TS (17%), especially with the karyotype 45, X. In this study we found no correlation between BP and aortic dimensions.