Cystathionine-β-synthase, Recombinant

Cat No.

DIA-293

Description

Cystathionine-β-synthase, also known as CBS, is an enzyme (EC 4.2.1.22) that in humans is encoded by the CBS gene. CBS uses the cofactor pyridoxal-phosphate (PLP) and can be allosterically regulated by effectors such as the ubiquitous cofactor S-adenosyl-L-methionine (adoMet). This enzyme belongs to the family of lyases, to be specific, the hydro-lyases, which cleave carbon-oxygen bonds. CBS is a multidomain enzyme composed of an N-terminal enzymatic domain and two CBS domains. The CBS gene is the most common locus for mutations associated with homocystinuria.

Abbr

CBS, Recombinant

Alias

CBS

Applications

This protein can be used for producing Hcy in vitro diagnosis Kit .

Appearance

Lyophilized powder

Enzyme Commission Number

EC 4.2.1.22

CAS No.

9023-99-8

Molecular Weight

56 KD

Purity

>90% (by SDS-PAGE)

Isoelectric point

6.49

pH Stability

7.4-8.5

Storage

The lyophilized powder should be stored at -20°C where it is stable for up to several years. The solution could be stored at 4°C where it is stable for up to 1 year. Repeated freezing and thawing cycles of the reconstituted solution is not recommended .