Seattle Police said it happened at about 6:45 p.m. near the intersection of Third Avenue and Pine Street. All five victims were transported to Harborview Medical Center.

Investigators said an argument took place outside the 7-Eleven and quickly escalated. It's believed the suspect walked away from a group of people, turned around, and fired at the crowd, according to police.

Additional police presence was already downtown for an unrelated anti-Trump rally, and crews were on the scene within one minute.

Seattle Police stressed the shooting was not at all connected to the anti-Trump rally.

Charelle Williams, a leasing agent who moved to the area from North Carolina two months ago, also heard the shots. He said he heard some pops and screams before people started scattering. He said it was shocking to see a shooting in Seattle.

"It’s kind of frightening," Williams said. "A bullet can have anybody’s name on it. You never see it coming."

WATCH: witnesses at downtown Seattle shooting had to hide under tables inside McDonald's at third & pine pic.twitter.com/PEv7UEz8Fm

Wednesday night two victims were in critical condition, but Thursday morning Harborview confirmed their conditions improved to serious. Two other victims are now in satisfactory condition while the fifth was released from the hospital overnight.

The five victims range in age from 20's to 50's. They sustained gunshot wounds to their chest, neck, and legs.

A man at Harborview Medical Center said his 26-year-old son was among the victims that has non-life-threatening injuries. His family waited at the hospital for several hours, worrying about their loved one.

"If there's anybody that does know anything I would appreciate you coming forward and helping the police out in solving this," said Jesse Baker. "Because it wasn't just my son, it was a couple other innocent people. And just as random - this shooting stuff has just gone too far, it really has."

Police are now reviewing surveillance video from businesses in the area where the shooting took place, working to identify the gunman. They're asking anyone with information to contact Seattle Police right away.