..Public health initiatives that promote moderate increases in physical activity may offer the best balance between efficacy and feasibility to improve cardiovascular health in sedentary populations...

Epidemiological evidence for the role of physical activity in reducing risk of type 2 diabetes and cardiovascular disease

..Public health initiatives promoting moderate increases in physical activity may offer the best balance between efficacy and feasibility to improve metabolic and cardiovascular health in largely sedentary populations...

..Large-scale randomized trials with clinical end points are necessary to minimize confounding and provide unbiased estimates of the balance of benefits and risks, yet data from such trials are scarce, especially among women...

Characteristics of the Modified Mini-Mental State Exam among elderly persons

..In a sedentary society, public health initiatives that promote moderate increases in physical activity may represent the optimal balance between efficacy, feasibility, and safety to achieve the desired cardioprotective effect...

Social disengagement and incident cognitive decline in community-dwelling elderly persons

..These findings also suggest that it is important to consider not only individual characteristics but also community attributes that mediate or modify the pathways through which socioeconomic conditions may influence health...

Postmenopausal hormone therapy: new questions and the case for new clinical trials

..The reduction in vasomotor symptoms must be weighed against other risks and benefits of treatment, but coronary disease is typically not a major factor in the equation for women who are recently menopausal...

Estimating the number of deaths due to obesity: can the divergent findings be reconciled?