Primary immunodeficiency diseases or disorders (PIDD or PI) are caused as part of the body’s immune system is missing or does not function normally, such that it is an inherited flaw in the immune system that increases the susceptibility to infections. Besides susceptibility to infections, PIDD may cause other health problems as well, including allergies, asthma, swollen joints, digestive tract problems, growth problems or an enlarged liver and spleen. The global primary immunodeficiency disease market is dominated by North America and Europe, collectively accounting for major share of the market in 2015. National PID registries worldwide, increasing healthcare expenditure and government support are the major factors driving the global primary immunodeficiency diseases market during the forecast period.