Turkey is becoming increasingly isolated in the Middle East, a region where Ankara’s political and economic clout was on a decade-long rise until the Arab Spring disrupted the political order. And Prime Minister Recep Tayyip Erdogan’s fiery rhetoric and intransigent foreign policies may just fuel Turkey’s loneliness.

The premier’s latest salvo came Tuesday, when Mr. Erdogan accused Israel of orchestrating the coup in Egypt that removed the Muslim Brotherhood’s Mohammad Morsi from the presidency, toppling the Turkish PM’s close ally. The military’s July 3 move to seize power in Cairo has reverberated across Turkey, where courts recently jailed scores of generals for an alleged plot to overthrow Mr. Erdogan, who faced popular protests throughout June.

Deeply upset by the ousting of its Islamic ally from power in Egypt by General Abdel Fattah Al-Sisi, Mr. Erdogan has struck an increasingly anti-U.S., anti-Western, anti-Semitic and, since Tuesday, also an anti-Arab tone, blaming leaders across the globe for supporting Egypt’s military putsch and failing to support the democratically elected president. The premier’s comments about “rich Arabs backing the dictators” in Egypt was widely interpreted as swipe against Mr. Erdogan’s Sunni allies in Saudi Arabia and the United Arab Emirates.

But it was the usual suspect, Israel, whom Mr. Erdogan pointed out as the main culprit.

“Israel is behind this. We have a document to back this,” the prime minister told his party’s provincial chiefs in Ankara on Tuesday, continuing with an anecdote from a panel held in France before the 2011 elections in Egypt, which brought the Muslim Brotherhood into power.

“A French intellectual, who was a Jew, together with [Israeli] Minister of Justice, said exactly this: Even if the Muslim Brotherhood won the election they will not win, because democracy is not the ballot box,” Mr. Erdogan said, referring to philosopher Bernard-Henri Lévy.

A press statement from Israel’s Foreign Ministry spokesman, confirmed by Israel’s Consulate General in Istanbul, noted that Mr. Erdogan’s accusation was “not worth commenting on.” A White House spokesman called the comments “offensive, unsubstantiated and wrong” in a press briefing in Washington.

Turkey has withdrawn its ambassador from Cairo for an unspecified period, and demonstrations in support of Mr. Morsi take place in Turkey on a daily basis. Ankara is also calling for the U.S., the U.N. Security Council and the Arab League to take immediate action against Egypt’s current military leadership.

While some analysts stressed that Tuesday’s speech was intended for a domestic audience, others said Mr. Erdogan’s words were isolating Turkey even further in the region.

“These speeches contribute to Turkey’s growing loneliness in the region. What else can be made out of rhetoric which implies that you are picking a fight with everybody,” said Soli Ozel, professor of International Relations at Istanbul’s Kadir Has University.

“Blaming Israel is nothing new, and Mr. Erdogan seems to believe in this theory. But he clearly doesn’t feel that these kinds of speeches will cost him a lot in the U.S,” said Hugh Pope, Turkey-Cyprus director for International Crisis Group.

The U.S., while announcing the postponement of its biannual military exercises with Egypt last week, seems reluctant to cancel its $1.5 billion in military and economic aid to Egypt, as demanded by Turkey.

“The West should learn the definition of democracy. If it doesn’t do that, these controversies and clashes will continue,” Mr. Erdogan said Tuesday.

Many Turkish analysts also argue that the much-discussed Turkish political model, which portrayed Mr. Erdogan’s government as an exemplary democratic Muslim country, is increasingly under threat or even outright passé. The criticism increased especially after the harsh police response against mostly peaceful demonstrators in nationwide anti-government Gezi protests in June.

Speaking off-the-record, some analysts also admit that there is an increasing worry over Mr. Erdogan’s worldview, which they say is getting increasingly out of touch with reality.

Turkey and Egypt “are part of the same game,” said Mr. Erdogan’s newly appointed chief advisor, Yigit Bulut, suggesting that Gezi protests in Turkey were also orchestrated by Israel.

“It is important to ask: Why were the important pillars of the Islamic world, Turkey and Egypt, selected? What is the macro-plan behind it?” Mr. Bulut wrote in his column in the pro-government Star daily on Wednesday. “It is crystal clear that especially after 2008, when Turkey had become more independent and powerful, both politically and economically, and come to the point of changing the 300-year course, the plan against our geography was set in motion! What has happened in Turkey and in Egypt were ‘the first act!’.”