DENVER — The Colorado State Patrol is urging drivers to be careful after five people were killed in different crashes around the state over the weekend.

Two people were killed and three others were seriously injured in a head-on crash in Douglas County on Sunday and a driver also died in Larimer County after hitting an embankment. A 34-year-old man died when his car rolled over Saturday in El Paso County. On Friday, a man died after being thrown from his SUV after going off the road in Fremont County.

The state patrol’s leader, Col. Matthew Packard, said in a tweet that he was “struggling between anger, frustration and heartbreak” over the crashes and that they each were preventable.

A massive fireball that engulfed people scooping up fuel spilling from a pipeline ruptured by thieves in central Mexico killed 21 people and badly burned 71 others in what was a chronicle of a tragedy foretold.

A large team has been assembled in Weld County to investigate a perplexing officer-involved shooting that's raising questions about the involvement of an off-duty Adams County sheriff's deputy who remains in critical condition after being shot by a LaSalle police officer.