製品の概要

Annexin V-Cy5 Apoptosis Detection Kit (ab14150) is based on the observation that soon after initiating apoptosis, cells translocate the membrane phosphatidyl-serine (PS) from the inner face of the plasma membrane to the cell surface. Once on the cell surface, PS can be easily detected by staining with a fluorescent conjugate of Annexin V, a protein that has a high affinity for PS. The one-step staining procedure takes only 10 minutes. Detection can be analyzed by flow cytometry or by fluorescence microscopy. Visit our FAQs page for tips and troubleshooting.

機能This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

関連疾患Pregnancy loss, recurrent, 3

配列類似性Belongs to the annexin family.Contains 4 annexin repeats.

ドメインThe [IL]-x-C-x-x-[DE] motif is a proposed target motif for cysteine S-nitrosylation mediated by the iNOS-S100A8/A9 transnitrosylase complex.A pair of annexin repeats may form one binding site for calcium and phospholipid.

Thank you for your enquiry.
I can confirm the concentration of annexin V in the ab14150 kit is 30 ug/ml.
I hope this will be helpful to you. Should you have any further questions, please do not hesitate to contact us.

Abcam Scientific Support

Answered on Jun 23 2011

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