nelfinavir oral and topotecan iv

nelfinavir oral will increase the level or effect of topotecan iv by affects how the drug is eliminated from the body (via what is known as the P-glycoprotein [MDR1] transporter). Product labeling for oral topotecan recommends avoiding this drug combination. The interaction with intravenous topotecan may be less severe but still likely of clinical significance.

nelfinavir oral and topotecan iv

nelfinavir oral will increase the level or effect of topotecan iv by P-glycoprotein (MDR1) efflux transporter. Product labeling for oral topotecan recommends avoiding use of p-glycoprotein inhibitors with oral topotecan. The interaction with intravenous topotecan may be less severe but still likely of clinical significance.

topotecan iv and nelfinavir oral

topotecan iv will increase the level or effect of nelfinavir oral by affects how the drug is eliminated from the body (via what is known as the P-glycoprotein [MDR1] transporter). Product labeling for oral topotecan recommends avoiding this drug combination. The interaction with intravenous topotecan may be less severe but still likely of clinical significance.

topotecan iv and nelfinavir oral

topotecan iv will increase the level or effect of nelfinavir oral by P-glycoprotein (MDR1) efflux transporter. Product labeling for oral topotecan recommends avoiding use of p-glycoprotein inhibitors with oral topotecan. The interaction with intravenous topotecan may be less severe but still likely of clinical significance.

Significant

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.