Gareth Bale will miss Wales' friendly with Spain on Thursday due to 'muscle fatigue', coach Ryan Giggs has confirmed.

Bale, who sat out Real Madrid's surprise Champions League loss to CSKA Moscow with a groin issue, was forced off late on in their 1-0 defeat at Deportivo Alaves on Saturday, with Julen Lopetegui revealing it was due to an injury.

The problem is not deemed to be serious and did not prevent him from joining up with the rest of the Wales squad.

But Bale will not face Spain at the Principality Stadium and is a doubt for the trip to the Republic of Ireland in the Nations League on Tuesday.

"Gareth has got a little bit of muscle fatigue and he won't be involved against Spain," Giggs said. "We don't want to take any risks and we are monitoring it every day.

"I would say he is 50-50 at the minute for the Ireland game. He had a scan last week, a couple of weeks ago with Real Madrid.