The area code for the International Space Station phone is a Houston area code, 281.

The WashPo feature has lots of great color on the ISS. Satellite TV is spotty, though you can probably see one of the satellites beaming out Breaking Bad to homes across the world just a few miles in distance. You can’t smoke and you can’t knock back a cold (or stiff one) after one of your 12-hour shifts. Standard astronaut stuff.But there was also the tidbit that the ISS has a phone number with a 281 area code. Remember back in May when we talked about area code superiority? At the time, I found that most Houstonians saw 281 as a dumpy scarlet letter which meant you lived outside the Inner Loop.
You cannot call the ISS though, but they can make calls out. All my prank call dreams are now dashed.