The Blackstone Valley Chamber of Commerce is the local chamber of commerce for Worcester county and many of the cities and towns in the Blackstone Valley. The chamber represents the business needs of over 450 businesses and thousands of employees in the area.[2]

Membership in the Blackstone Valley Chamber of Commerce also includes membership in the Worcester Regional Chamber of Commerce.[3]

In the Summer of 2012, the chamber teamed up with State Senator Michael Moore, the Central Massachusetts Center for Business and Enterprise (CMCBE), and the Massachusetts Growth Capital Corporation (MGCC), and others, in an effort is to extend lines of credit to small businesses for expansion and to help hire new employees.[4]