“As a breast cancer survivor, I personally understand the importance of preventive care to make sure more women can avert this disease or at least detect it early on,” Heitkamp wrote in a statement Wednesday.

“As a young survivor of breast cancer, I know how vital it is for young women to actively manage their breast health,” Wasserman Schultz added.

The backlash from the draft recommendation has been fierce. The debate has pitted groups like the American Cancer Society against Breast Cancer Action, which penned an op-ed in the Washington Post on Tuesday entitled, "Stop routine breast cancer screenings.”

The lawmakers wrote in their letter to the Department of Health and Human Services that the recommendation could ultimately mean that cases of breast cancer go undetected in women across the country – particularly those with fewer means to pay for the tests.

“Years of science and medicine have shown that appropriate screening can lead to early detection and save lives,” the group of senators wrote to HHS Secretary Sylvia Mathews Burwell.

The United States Preventive Services Task Force recommended last month that fewer women should receive biennial mammograms if they are not at high-risk for developing the disease. Similar guidance was also issued in 2009, which received similarly strong opposition and was essentially shelved.