Thanks st_albert, I will try and tell you how it works.
A friend advised me that also proves the following:

Within content.opf ePub file appears in the ISBN referenced as follows: 978-987-04-1775-0

That is, the ISBN appears with dashes between numbers, as the name of the file and the metadata should be no hyphens.

The logic is that in all places where reference is made to go ISBN without hyphens because if you cross the load data in Libranda epub digits do not match and it is normal EAN error report like the one shown in this case.

It is advisable to check all places where it appears in the ePub ISBNs and remove scripts.

After saving the content.opf, re-compress the entire folder and rename the file. Zip. Epub