"Normally we would do this privately, but given that the gossip industry cannot resist an opportunity to speculate and invent, we wanted to convey the truth directly," said the statement from Aniston's publicist Stephen Huvane.

The "Friends" star and "The Leftovers" actor said they will remain friends in a statement released to the Associated Press. Lester Cohen/WireImage via Getty Images

The pair says they are "two best friends who have decided to part ways as a couple, but look forward to continuing our cherished friendship."

Theroux is known for his role on HBO's "The Leftovers," which recently ended its series run June 2017.

Aniston was previously married to Brad Pitt for five years before they divorced in 2005.