Abstract

Background

Recently, radiopharmaceutical scanning with Tc-99m-MIBI was reported to depict areas
with active bone disease in multiple myeloma (MM) with both high sensitivity and specificity.
This observation was explained by the uptake of Tc-99m-MIBI by neoplastic cells. The
present investigation evaluates whether Tc-99m-MIBI imaging and magnetic resonance
imaging (MRI) perform equally well in detecting myelomatous bone marrow lesions.

Methods

In 21 patients with MM, MRIs of the vertebral region TH12 to S1 and whole body scans
with Tc-99m-MIBI were done.