Histological analysis of core biopsy of breast lesions takes a minimum of 24 h, but imprint cytology of a core biopsy can be reported within an hour. This study validates the accuracy of imprint cytology from core biopsy of breast lesions obtained under ultrasound control.

One hundred and fifty consecutive core biopsies from breast lesions of 142 patients were performed. The cores were placed on six microscopy slides to obtain imprint cytology. Imprint cytology and routine histology of the cores were assessed independently by two pathologists.

Imprint cytology of core biopsies correlates well with subsequent histological results and could be used to provide a rapid preliminary diagnosis. This rapidly available technique could reduce anxiety in patients with benign lesions and help treatment planning in patients with breast cancer.