Using Prusa Slic3r with Mendel90?

I have recently started using Slic3r 1.2.9 on my Mendel90, and I am pleased with the simplified UI and the fact that it is more regularly updated than Skeinforge. I have come across the Prusa edition of Slic3r and am considering downloading it to use on the Mendel90.

Are there any immediate changes, recommendations, warnings, etc. that I should know beforehand about using the Prusa edition of Slic3r for my Mendel90?