Databases

Neighborhood

Groups of genes that are frequently observed in each other's genomic neighborhood.

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Phatr23224

Predicted protein (710 aa)

Predicted Functional Partners:

Phatr11720

Predicted protein (69 aa)

0.903

Phatr9639

Predicted protein (545 aa)

0.899

Phatr7848

Predicted protein (135 aa)

0.529

Phatr35383

Predicted protein (332 aa)

0.507

Phatr28794

V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V- ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase (818 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 annotation

node2 annotation

score

Phatr11720

Phatr15031

Predicted protein

Predicted protein; Belongs to the PI3/PI4-kinase family

0.820

Phatr11720

Phatr23224

Predicted protein

Predicted protein

0.903

Phatr11720

Phatr28794

Predicted protein

V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V- ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase

0.644

Phatr11720

Phatr30282

Predicted protein

Predicted protein; Belongs to the PI3/PI4-kinase family

0.820

Phatr11720

Phatr9639

Predicted protein

Predicted protein

0.972

Phatr15031

Phatr11720

Predicted protein; Belongs to the PI3/PI4-kinase family

Predicted protein

0.820

Phatr15031

Phatr23224

Predicted protein; Belongs to the PI3/PI4-kinase family

Predicted protein

0.435

Phatr15031

Phatr9639

Predicted protein; Belongs to the PI3/PI4-kinase family

Predicted protein

0.655

Phatr23224

Phatr11720

Predicted protein

Predicted protein

0.903

Phatr23224

Phatr15031

Predicted protein

Predicted protein; Belongs to the PI3/PI4-kinase family

0.435

Phatr23224

Phatr28794

Predicted protein

V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V- ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase

0.472

Phatr23224

Phatr30282

Predicted protein

Predicted protein; Belongs to the PI3/PI4-kinase family

0.435

Phatr23224

Phatr35383

Predicted protein

Predicted protein

0.507

Phatr23224

Phatr7848

Predicted protein

Predicted protein

0.529

Phatr23224

Phatr9639

Predicted protein

Predicted protein

0.899

Phatr28794

Phatr11720

V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V- ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase

Predicted protein

0.644

Phatr28794

Phatr23224

V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V- ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase

Predicted protein

0.472

Phatr30282

Phatr11720

Predicted protein; Belongs to the PI3/PI4-kinase family

Predicted protein

0.820

Phatr30282

Phatr23224

Predicted protein; Belongs to the PI3/PI4-kinase family

Predicted protein

0.435

Phatr30282

Phatr9639

Predicted protein; Belongs to the PI3/PI4-kinase family

Predicted protein

0.655

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: