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Authors

van Kampen, P.J. MD

Martina, J.D. MD

Vos, P.E. MD, PhD

Hoedemaekers, C.W.E. MD, PhD

Hendricks, H.T. MD, PhD

Abstract

Background: Heterotopic ossification (HO) is a frequent complication after traumatic brain injury (TBI). The current preliminary study is intended to provide additional data on the potential roles that brain injury severity, concomitant orthopaedic trauma, and specific intensive care complicating events may play in the prediction of HO in patients who have sustained severe TBI.

Conclusion: Prolonged coma duration and mechanical ventilation, coexistent surgically treated bone fractures and clinical signs of autonomic dysregulation should be given further consideration as potential risk factors for developing clinically relevant HO. Larger-scale studies are needed to develop a valid risk profile that takes into account the interrelationships between variables.