Eligibility for anti-tumour necrosis factor (TNF) therapy in most European countries is restricted to severe, active rheumatoid arthritis (RA). The DAS28 score is a marker of disease severity and incorporates one of two inflammatory markers, erythrocyte sedimentation rate (ESR) or C-reactive protein. We aimed to determine the relation between genetic… (More)

Objective To identify metabolomic changes in lung tissue associated with lung injury induced by mechanical ventilation (VILI) in animals with sepsis, using for the first time a global unbiased metabolomic fingerprinting approach. Methods Rats received cecal-ligation and puncture (CLP) or sham operation, and 24 h later underwent mechanical ventilation for… (More)

A total of 25 high yielding tomato accessions were selected for the characterization that helped in the reliable varietal selection programme for breeding. All tomato accessions were analyzed by two parameters e.g. morphological and molecular parameters. For morphological characterization the plant height, shape, size, leaf length and width, and fruit size,… (More)