IACC Autism Spectrum Disorder Research Portfolio Analysis: Project Listing
Project Id Project Number Sub Project Number Funder Principal Investigator Project Title Project Description Fiscal Year Funding Category Subcategory Strategic Plan Objective Objective Status Code Arra Funded? Federal/Private Institution State/Country Project Status Web Link 1 Web Link 2 Web Link 3 Active Current Award Period
Project Id: 2696 1R21HD057808-01A1 None National Institutes of Health Rahbar, Mohammad Epidemiological research on autism in Jamaica The prevalence of autism spectrum disorders (ASD) appears to be on the rise in developed countries and has become a serious public health concern. In most developing countries, however, the nature and prevalence of factors associated with ASDs are unknown. The long term goal of this planning project is to develop capacity for conducting large scale population-based ASD studies in Jamaica. First, the diagnostic criteria used in Jamaica and the United States will be compared. Then, questionnaires regarding the demographic and socioeconomic position, occupation, and drinking habits of each child's parents will be used, and information will be gathered about family history of developmental disorders, family size, birth order of the affected child, and whether the child is taking any medications. An age and sex matched case-control study, including a dietary questionnaire, will also be conducted to investigate whether environmental exposures to mercury, lead, arsenic, and cadmium play a role in autism. Blood and saliva samples will be collected to determine if any DNA polymorphisms that might affect interactions with heavy metals are present in children with ASD. New knowledge of potential environmental risk factors for ASD may arise from this research, thereby reducing physical, psychological, and economic burdens on the child, family, and society and helping parents make decisions about avoiding exposure to environmental contaminants. $146,500.00 Risk Factors N/A Question 3: Long-term Objective D Green dot: Objective has greater than or equal to the recommended funding. No Federal University of Texas Health Science Center at Houston Texas New http://projectreporter.nih.gov/project_info_description.cfm?aid=7624563&icde=6639095 No URL available. No URL available. active na
Project Id: 2485 2021 None Autism Speaks Sourander, Andre Early developmental risk factors for autism in a national birth cohort This pilot study will establish a new project called the Finnish Prenatal Study of Autism and Autism Spectrum Disorders (FiPS-A). The FiPS-A is based on the Finnish Maternity Cohort (FMC), which consists of virtually all births in Finland (N=1.1 million) from 1987- 2005. The investigators will use maternal medical and exposure history collected during pregnancy to examine if infection, hormonal abnormalities, and smoking are related to an increased risk of autism in their children in a subset of these 1.1 million births. This study will also be able to identify potential early risk factors, including improper growth and development before the child was diagnosed, to assess whether these parameters can be included in early signs of autism. In addition to medical data, this project has the ability to analyze blood samples that were drawn during pregnancy in a random sample of children who are diagnosed with autism and a random sample of children without autism, all of whom were in the national FMC cohort. $59,457.00 Risk Factors N/A Question 3: Long-term Objective D Green dot: Objective has greater than or equal to the recommended funding. No Private Turku University Finland Ongoing http://www.autismspeaks.org/science/grants/early-developmental-risk-factors-autism-national-birth-cohort?destination=science%2Fgrant-search%2Fresults%2Fsourander No URL available. No URL available. not active na
Project Id: 2454 2210 None Autism Speaks Santangelo, Susan Maternal dietary factors and risk of autism spectrum disorders Research suggests that autism may result from environmental factors that act during prenatal development. One idea is that a pregnant woman's diet could influence prenatal brain development, perhaps in a way that increases autism risk. Relatively little research has been dedicated to understanding how maternal dietary factors could influence brain development in offspring. One interesting dietary factor is intake of omega-3 fatty acids, which are found in fish and nut oils; these fatty acids may act in the brain to promote neural growth.Dr. Santagelo's fellow will determine whether women with low intakes of omega-3 fatty acids during pregnancy have increased risk of having a child with autism. The women studied will be from The Nurses' Health Study II cohort, a large cohort of over 100,000 female United States nurses who have been followed prospectively since 1989. The information collected on this group includes medical, obstetrical, and prospectively collected dietary factors, including omega-3 fatty acid intake. In 2005, over 800 women in the cohort reported having had a child with an autism diagnosis. This study will compare omega-3 fatty acid intakes in women with children with autism to the intake of women without children with autism in order to characterize the relationship between maternal diet and risk of autism. $32,000.00 Risk Factors N/A Question 3: Long-term Objective D Green dot: Objective has greater than or equal to the recommended funding. No Private Harvard Medical School Massachusetts Ongoing http://www.autismspeaks.org/science/grants/maternal-dietary-factors-and-risk-autism-spectrum-disorders?destination=science%2Fgrant-search%2Fresults%2FMaternal+dietary+factors+and+risk+of+autism+spectrum+disorders No URL available. No URL available. active na
Project Id: 2047 1788 None Autism Speaks Ascherio, Alberto Maternal risk factors for autism in the Nurses Health Study II – a pilot study Established in 1989, the Nurses Health Study II has prospectively evaluated many aspects of women's health in a cohort of over 100,000 women in the United States. The information collected on this group include medical, obstetrical, and prospectively collected dietary factors, as well as neurodevelopmental diagnosis of children born to women in this cohort. This allows for a unique opportunity to investigate a wide range of environmental factors, including maternal dietary and reproductive factors, which may be associated with risk of developing autism spectrum disorders. Diet and medical history of mothers with a child with autism, as well as those who did not report a child diagnosed with autism, will be studied using information gathered prior to pregnancy. These children and their parents will be screened using the social responsiveness scale (SRS) and then followed up by the Autism Diagnostic Instrument-Revised (ADI-R). Utility of the SRS, which measures autism severity using one quantifiable score, as a diagnostic instrument will also be investigated in this study. $0.00 Risk Factors N/A Question 3: Long-term Objective D Green dot: Objective has greater than or equal to the recommended funding. No Private Harvard School of Public Health Massachusetts Ongoing http://www.autismspeaks.org/science/grants/maternal-risk-factors-autism-nurses-health-study-ii-pilot-study?destination=science%2Fgrant-search%2Fresults%2FMaternal+risk+factors+for+autism+in+the+Nurses+Health+Study+II+–+a+pilot+study No URL available. No URL available. not active na
Project Id: 2172 5U10DD000181-04 None Centers for Disease Control and Prevention Croen, Lisa Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) - California Centers of Excellence for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) is a collaborative network which is conducting an epidemiologic study of risk factors for autism, called the Study to Explore Early Development (SEED). SEED will be one of the largest collaborative epidemiologic studies to date to investigate the correlates and causes of autism spectrum disorders (ASD). $1,386,673.00 Risk Factors N/A Question 3: Long-term Objective D Green dot: Objective has greater than or equal to the recommended funding. No Federal Kaiser Foundation Research Institute California Ongoing http://projectreporter.nih.gov/project_info_description.cfm?aid=7681112&icde=6626348 No URL available. No URL available. active na
Project Id: 2555 5U10DD000180-04 None Centers for Disease Control and Prevention Miller, Lisa Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) - Colorado Centers of Excellence for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) is a collaborative network which is conducting an epidemiologic study of risk factors for autism, called the Study to Explore Early Development (SEED). SEED will be one of the largest collaborative epidemiologic studies to date to investigate the correlates and causes of autism spectrum disorders (ASD). $1,192,664.00 Risk Factors N/A Question 3: Long-term Objective D Green dot: Objective has greater than or equal to the recommended funding. No Federal Colorado Department of Health and Environment Colorado Ongoing http://projectreporter.nih.gov/project_info_description.cfm?aid=7681097&icde=6626620 No URL available. No URL available. active na
Project Id: 2707 1U10DD000498-01 None Centers for Disease Control and Prevention Reed, Phillip Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) - Data Coordinating Center The Centers of Excellence for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) Data Coordinating Center provides information technology (IT) and data management support for the Study to Explore Early Development (SEED). CADDRE is a collaborative network which is conducting an epidemiologic study of risk factors for autism (SEED), which will be one of the largest collaborative epidemiologic studies to date to investigate the correlates and causes of autism spectrum disorders (ASD). $700,000.00 Risk Factors N/A Question 3: Long-term Objective D Green dot: Objective has greater than or equal to the recommended funding. No Federal Michigan State University Michigan Ongoing http://projectreporter.nih.gov/project_info_description.cfm?aid=7774643&icde=6833981 No URL available. No URL available. active na
Project Id: 2708 3U10DD00007-05S1 None Centers for Disease Control and Prevention Reed, Phillip Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) - Data Coordinating Center The Centers of Excellence for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) Data Coordinating Center provides information technology (IT) and data management support for the Study to Explore Early Development (SEED). CADDRE is a collaborative network which is conducting an epidemiologic study of risk factors for autism (SEED), which will be one of the largest collaborative epidemiologic studies to date to investigate the correlates and causes of autism spectrum disorders (ASD). $36,170.00 Risk Factors N/A Question 3: Long-term Objective D Green dot: Objective has greater than or equal to the recommended funding. No Federal Michigan State University Michigan New http://projectreporter.nih.gov/project_info_description.cfm?aid=7838718&icde=6626666 No URL available. No URL available. active na
Project Id: 2758 Multiple Contracts None Centers for Disease Control and Prevention Schendel, Diana; Schieve, Laura Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) - Georgia Centers of Excellence for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) is a collaborative network which is conducting an epidemiologic study of risk factors for autism, called the Study to Explore Early Development (SEED). SEED will be one of the largest collaborative epidemiologic studies to date to investigate the correlates and causes of autism spectrum disorders (ASD). $868,924.00 Risk Factors N/A Question 3: Long-term Objective D Green dot: Objective has greater than or equal to the recommended funding. No Federal Centers for Disease Control and Prevention (CDC) Georgia Ongoing No URL available. No URL available. No URL available. active na
Project Id: 2251 5U10DD000183-04 None Centers for Disease Control and Prevention Fallin, Margaret Danielle Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) - Maryland Centers of Excellence for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) is a collaborative network which is conducting an epidemiologic study of risk factors for autism, called the Study to Explore Early Development (SEED). SEED will be one of the largest collaborative epidemiologic studies to date to investigate the correlates and causes of autism spectrum disorders (ASD). $1,937,600.00 Risk Factors N/A Question 3: Long-term Objective D Green dot: Objective has greater than or equal to the recommended funding. No Federal Johns Hopkins University Maryland Ongoing http://projectreporter.nih.gov/project_info_description.cfm?aid=7682087&icde=7011199 No URL available. No URL available. active na
Project Id: 2182 5U10DD000184-04 None Centers for Disease Control and Prevention Daniels, Julie Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) - North Carolina Centers of Excellence for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) is a collaborative network which is conducting an epidemiologic study of risk factors for autism, called the Study to Explore Early Development (SEED). SEED will be one of the largest collaborative epidemiologic studies to date to investigate the correlates and causes of autism spectrum disorders (ASD). $1,209,900.00 Risk Factors N/A Question 3: Long-term Objective D Green dot: Objective has greater than or equal to the recommended funding. No Federal University of North Carolina at Chapel Hill North Carolina Ongoing http://projectreporter.nih.gov/project_info_description.cfm?aid=7681118&icde=7011209 No URL available. No URL available. active na
Project Id: 2673 5U10DD000182-04 None Centers for Disease Control and Prevention Pinto-Martin, Jennifer Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) - Pennsylvania Centers of Excellence for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) is a collaborative network which is conducting an epidemiologic study of risk factors for autism, called the Study to Explore Early Development (SEED). SEED will be one of the largest collaborative epidemiologic studies to date to investigate the correlates and causes of autism spectrum disorders (ASD). $1,565,617.00 Risk Factors N/A Question 3: Long-term Objective D Green dot: Objective has greater than or equal to the recommended funding. No Federal University of Pennsylvania/Children's Hospital of Philadelphia Pennsylvania Ongoing http://projectreporter.nih.gov/project_info_description.cfm?aid=7681113&icde=7011220 No URL available. No URL available. active na
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