Semi-urban ecotones exist on the periphery and in the midst of many human population centers. This article addresses the need for and nature of an ethos appropriate to inter-species contact in such zones. It first examines the historical and contemporary intellectual resources available for developing this kind of ethic, then surveys the range of possible relationships between humans and other animals, and finally investigates the morality of multi-species neighborhoods as a promising model. Discussion of these themes has the effect, in conclusion, of dismantling notorious dualisms traditionally associated with the geographic imagination (city/wild, human/animal, nature/culture).