Results:

A total of 60 lower limb chronic wounds were imaged. qPCR analysis of wound tissue biopsies obtained from regions of red fluorescence yielded a PPV of 100 %. Total bacterial load in these areas was ≥ 104 CFU/g. Semi-quantitative culture analysis of curettage scrapings from regions of red fluorescence yielded a PPV of 100 %, with predominately moderate or heavy bacterial growth observed. There were nine distinct bacterial species were detected by red fluorescence, all common pathogens in chronic wounds. Staphylococcus aureus was the most prevalent species observed.

The MolecuLight i:X™ Imaging Device is approved by Health Canada and has CE marking for sale in Canada and the European Union. The MolecuLight i:X™ Imaging Device has received FDA clearance. MolecuLight® and Look to Heal® are registered trademarks in Canada, the US and the EU.