Vache was born November 17, 1888, in Santa Monica, California. It took him until the age of 36 to reach the Major Leagues. On April 16, 1925, Vache made his Major League debut for the Boston Red Sox. Throughout the year, Vache played 110 games.

His final game was September 22 that year; it was his only season in Major League Baseball, despite hitting .313 in the season.