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Possible to activate Akali's passives with runes at level 20?

So I'm almost level 20 and played my favorite champ Akali for many levels, but I want to bring her to her full potential with runes. But with not all my slots opened yet, I'm wondering if I am able to go about this as soon as possible, combining with my masteries. ^^ If it isn't possible to get both passives, could I get one or the other at least?

Don't do that, is stupid, ok get early spell vamp, I will see you throwing kamas.
Ok get extra damage for your Q nice.
I prefer magic pen, and movement speed, also I build her hybrid with mobility boots, I was playing her for a long 1 year or a bit more, and I enjoy and laugh a lot when I see an enemy akali starting with both hands actives.
Mobility is the perfection for an assasin, your passive won't be useful at very early game, seriously, you know that, after 6 is there when you need your passives, regaeblade solves it, then hextech, then trinity force/lich's bane.
Try it, you will feel the true akali's power.

Save your IP for runes that you'll genuinely want for a wide mix of champions once you hit 30. You'll be glad you did. Getting what you need to trigger her passive before 30 will involve buying AP Seals and Glyphs which are pretty suboptimal and not very useful for a lot of champions. You'd probably just be better off buying Armor yellows and MR blues, then triggering the extra damage from AP with your first Amplifying tome.

However, flat attack damage runes are definitely runes you'll want to have. 7 flat attack damage reds + masteries can get you the damage you need for spellvamp at level 1 with masteries (you'll need level 21 summoner though). AD reds are also useful on top-laners, junglers, AD carries, and even some supports, so you can't really go wrong with them.