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CHICAGO, March 18, 2013 (GLOBE NEWSWIRE) -- MAKO
Surgical Corp. (Nasdaq:MAKO), the leader in robotic arm
assisted partial knee and total hip arthroplasty worldwide, today announced that
it will showcase its MAKOplasty®
Total Hip Arthroplasty (THA) and Partial
Knee Resurfacing applications at the American Academy of Orthopaedic
Surgeons 2013 Annual Meeting (AAOS), March 20-23 at McCormick Place in Chicago.
During the meeting, orthopedic surgeons will deliver presentations and provide
hands-on demonstrations in MAKO's booth #212.

MAKOplasty THA is the company's latest application for its RIO®
Robotic Arm Interactive Orthopedic System, which will be highlighted by the
company during the meeting. The RIO system overcomes limitations of conventional
arthroplasty surgeries by providing auditory, visual and tactile guidance that,
when integrated with the touch and feel of the surgeon's skilled hand, provides
consistently reproducible precision in total hip and partial knee surgeries.
MAKO's robotic arm assisted THA may result in a reduction in complications
associated with conventional hip replacement surgery.

"With total hip replacement using MAKO robotic-arm assistance, I am a better
surgeon because I perform 95 percent of my operations with the implants always
in the correct position," said Lawrence
Dorr, M.D., clinical professor of orthopedics at Keck School of Medicine at
University of Southern California in Los Angeles. "This is better than the
Harvard data, which showed 47 percent of the implants in the correct position1.
Even in my own practice, the MAKO robotic-arm assistance provides me with
greater precision compared to when I perform the hip replacement using my
experience only. Every patient who comes to me expects me to give him or her a
precise operation. My consistent results allow me to fulfill the trust the
patient puts in me," said Dr. Dorr.

"Knowing I have an accurate hip reconstruction gives me confidence I have
minimized the risks for impingement and its consequent complications of
dislocation, pain and accelerated wear. I also believe I have optimized the
chance for durability of the hip replacement of 30 years," continued Dr.
Dorr.

Hip replacement with MAKO's robotic-arm assistance builds upon the proven
benefits of MAKOplasty Partial Knee Resurfacing, developed as an advanced
treatment option designed to relieve pain for adults living with early to
mid-stage osteoarthritis that has not yet spread to all three compartments of
the knee. The use of the RIO system in MAKOplasty partial knee resurfacing leads
to implant component placement that is two to three times more accurate than
manual techniques2. Studies also show that patients with bicompartmental
MAKOplasty have improved function over those with total knee replacement
surgery, and that these MAKOplasty patients demonstrate better post-operative
range of motion and quadriceps strength compared to total knee
arthroplasty3.

"The MAKOplasty procedure with the RIO system for THA and partial knee
resurfacing not only improves accuracy and reproducibility in surgery, it
improves my patients' recovery," said Robert
C. Marchand, M.D., a partner at South County Orthopedics in Wakefield, R.I.,
and one of the presenters in MAKO's booth during the AAOS 2013 Annual Meeting.
"With partial knee resurfacing for example, I am able to use the RIO system to
create an anatomical model of the patient's knee and develop a patient specific
plan for optimal implant positioning based on the patient's individual anatomy.
The RIO provides feedback and guidance, thereby preventing me from removing bone
form outside the specified plan, and it allows for accurate implant placement.
Our patients recover more quickly compared to conventional techniques and their
post-operative range of motion is improved as well."

Additional studies describing the clinical success using MAKO's RIO system
and its RESTORIS® family of implants when performing MAKOplasty procedures are
beginning to appear in peer-reviewed journals, and a body of growing clinical
data continues to be presented at academic meetings worldwide. In a recent oral
presentation of a multi-center trial, the authors presented key results
regarding the accuracy of robotic arm cup placement in total hip procedures, and
reported 87 percent were positioned in an acceptable range. This compares
favorably to data from a recently published Massachusetts General Hospital (MGH)
study, which evaluated 1,823 hips receiving manual total hip arthroplasty, which
reported 47 percent of cups were placed in an acceptable rage. Mal-positioning
of acetabular cups in conventional hip replacement surgery may lead to
impingement and implant wear that can cause dislocation4. Nearly 300,000 primary
hip replacement surgeries are performed annually in the United States using
conventional technique.

Another multi-center study of MAKOplasty partial knee cases using RESTORIS
MCK onlay medial unicompartmental implants, found very low two year
post-operative revision rates of 0.4 percent, compared to two year revision
rates reported at 4.0 percent and 4.4 percent respectively in the Swedish and
Australian registries5.

As of December 31, 2012, approximately 23,000 MAKOplasty procedures have been
performed worldwide.

About MAKO Surgical Corp.

MAKO
Surgical Corp. is a medical device company that markets its RIO® Robotic-Arm
Interactive Orthopedic system, with specific applications for partial
knee resurfacing and total hip
replacement, and proprietary RESTORIS® Family of Implants for orthopedic
procedures called MAKOplasty®.
The RIO is a surgeon-interactive tactile surgical platform that incorporates a
robotic arm and patient-specific visualization technology, which enables
accurate, consistently reproducible bone resection for accurate insertion and
alignment of RESTORIS knee and hip implants. The MAKOplasty solution
incorporates technologies enabled by an intellectual property portfolio
including more than 300 U.S. and foreign, owned and licensed, patents and patent
applications. Additional information can be found at www.makosurgical.com.