Omudhome Ogbru, PharmD

Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

Jay W. Marks, MD

Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

How much Lotrisone should I use (dosage)?

Lotrisone cream is gently massaged into the affected skin and
surrounding area in the morning and evening. The treated skin should not be
bandaged, covered, or wrapped in order to avoid excessive absorption of
Lotrisone into the body.

Lotrisone cream or lotion should not be used for more than 2 weeks for
treatment of
tinea corporis or tinea cruris. If there is no clinical improvement
after one week of treatment, the diagnosis should be reviewed.

Lotrisone should
not be used longer than 4 weeks for treatment of
tinea pedis. If there is no
clinical improvement after 2 weeks of treatment, the diagnosis should be
reviewed. These limits on duration of use are based on the clinical studies that
were used by the FDA to approve Lotrisone and concerns that with longer use
absorption of betamethasone might be enough to have effects on the body.

Amounts
greater than 45 g per week of Lotrisone cream or amounts greater than 45 mL per
week of Lotrisone lotion should not be used.

What drugs or supplements interact with Lotrisone?

Long-term use or withdrawal of topical
corticosteroids may aggravate
psoriasis. Therefore, there should be an interval
of at least 1 week between the discontinuance of topical steroids and the
starting of
psoriasis treatment with anthralin (Psoriatec).

What else should I know about Lotrisone?

What preparations of are available?

How should I keep this medicine stored?

Lotrisone can be stored at room temperature, cream at 2 C to 30 C (36 F to 86 F) and lotion at 15 C to 30 C (59 F to 86 F).

How does Lotrisone work?

Lotrisone prevents growth
of several types of fungi by preventing production of the membranes that
surround fungal cells. Betamethasone is a synthetic corticosteroid that is used
topically on the skin.
Corticosteroids suppress inflammation as well as the
body's immune response.