In a statement released to Zap2It on Sunday, the Supernatural star's manager revealed:

"Jared wanted everyone to know he loves meeting his fans around the world and was very upset at having to cancel his trips to Rome and Australia. Jared has pushed himself to his limits and is suffering from exhaustion. His SPN family is so important to him, and he asks that they Always Keep Fighting.
At this time he needs to be home with his family. He's doing better already and is excited about shooting Supernatural Season 11 this July. For now he's taking a break, but is so appreciative of his fans, and sees and feels their love and support."

Awe! It sounds like he was just exhausted and needed a little rest and relaxation.

Sometimes we all need a little break from working so hard to spend quality time with our family.

His Supernatural costar Jensen Ackles talked about Jared's absence from JIBCON over the weekend, saying: