Also, birth defects occurred in the lyrica medication offspring of male lyrica medication animals who were treated with pregabalin. Patients with creatinine clearance (CLcr) between 30 to 60 mL/min were randomized to 75 mg, 150 mg, or placebo twice daily. Some patients experienced a decrease in pain as early as week 1, which persisted throughout the study.

Patients were enrolled with a minimum mean baseline pain score is lyrica a narcotic of greater than or equal is lyrica a narcotic to 4 on an 11-point numeric pain rating scale and a score of greater than or equal to 40 mm on the 100 mm pain visual analog scale (VAS).