Marisnick will undergo surgery on his fractured right thumb and is expected to miss six-to-eight weeks.

Marisnick is set to undergo surgery on Friday, which would place an optimistic return for the end of October, effectively ending his regular season and casting doubt on whether he will be able to return to the club even if the Astros are still playing come the tail-end of the playoffs. He suffered the injury during Wednesday's game while sliding into second base, and will immediately begin rehabbing following Friday's procedure. In his place, Cameron Maybin and Derek Fisher are in line to see an increase in action.

Manager A.J. Hinch said Marisnick (thumb) is flying back to Houston to see the team doctors, Brian McTaggart of MLB.com reports.

Hinch didn't sound optimistic, saying "we'll know more in the next of couple days, but it doesn't look good." Given what Hinch said and how late it is in the year, it sounds like Marisnick's season could be over, though that will be determined in the coming days. Cameron Maybin and Derek Fisher could see a few extra starts in the outfield with Marisnick sidelined.

Marisnick was removed from Wednesday's game in the third inning with an apparent hand injury, Jake Kaplan of the Houston Chronicle reports.

Marisnick came up shaking his hand after sliding into second base in the top of the third inning, and he was subsequently removed before the bottom half of the frame. Derek Fisher subbed in for him in the outfield. Marisnick was seen heading into the clubhouse with a trainer, so more details about the injury should come forth shortly.