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VMA (Vanillylmandelic Acid), 24-Hour Urine without Creatinine

CPT Code(s)

Methodology

Limitations

Requires accurate 24-hour urine collection.

Reference Range(s)

3-8 Years

≤2.3

mg/24 h

9-12 Years

≤3.4

mg/24 h

13-17 Years

≤3.9

mg/24 h

>17 Years

≤6.0

mg/24 h

Clinical Significance

Vanillylmandelic acid (VMA) is the major urinary product resulting from the metabolic degradation of catecholamine, norepinephrine and epinephrine. Elevated concentrations of VMA are commonly found in cases of catecholamine secreting tumors such as pheochromocytoma, neuroblastoma, and ganglioneuroma.Drugs which can interfere with testing due to physiologic response: clonidine, L-dopa, methocarbamol, monoamine oxidase inhibitors, reserpine, salicylates.

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

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