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Epclusa achieves best SVR rates in patients with HCV genotype 3

VIENNA — Patients with hepatitis C genotype 3 and compensated cirrhosis had higher rates of sustained virologic response after treatment with Epclusa and ribavirin than with Epclusa alone or combined Sovaldi and Daklinza with ribavirin.

Kate Drysdale, MBBCh, from the Queen Mary University of London in the United Kingdom, presented data gathered from a national registry of patients with hepatitis C in England. According to Drysdale, HCV treatment within this registry is dictated by local prioritization and the lowest cost of acquisition determines choice of direct-acting antivirals.

Drysdale and colleagues analyzed registry data on 37,693 patients with HCV. Of the 14,603 adult patients treated with DAAs with a per protocol 12-week outcome, 13,959 achieved sustained virologic response for an overall SVR rate of 95.59%.

The study is aimed at assessing the safety and immunogenicity of HCV prime-boost vaccinations ChAd3-hliNSmut and MVA-hliNSmut, administered intramuscularly in healthy volunteers and DAA treated patients. To read the entire study, click here Share This PageFollow Us … Continue reading → The post The study is aimed at assessing the safety and immunogenicity of HCV […]

The purpose of this study is to evaluate the efficacy and tolerability of DAA-based regimens in the clinical practice in HIV/HCV-coinfected patients. Hypothesis: The efficacy and tolerability of all DAA-based regimens in the clinical practice is different to what is … Continue reading → The post Real-life Security and Efficacy of DAA-based Therapy in 1,000 […]