This meeting took place in 2003

For a complete list of the meetings for the upcoming/current season,
see our meeting list, or search for a meeting.

Drug Target Validation: Gene Suppression (B1)

Organizer(s) Peter B. Dervan, Stephen W. Fesik and Michael Briggs

January 17—22, 2003

Granlibakken Tahoe • Tahoe City, CA USA

Abstract Deadline: Sep 17, 2002

Late Abstract Deadline:

Scholarship Deadline:

Early Registration Deadline: Nov 18, 2002

Sponsored by Abbott Laboratories

Summary of Meeting:There is an enormous interest in the application of diverse chemical and biological tools to control the expression of specific genes or compromise the activities of specific mRNAs and proteins. The biotechnology industry develops these tools for plant and animal engineering, the pharmaceutical industry makes use of these tools to validate drug targets, and the medical community investigates a subset of these reagents as therapeutics in their own right.
The purpose of this Keystone Symposium is to review the utility of chemical and biological approaches to selectively turning gene activity off at the transcriptional, post-transcriptional and protein level- especially with reference to functional genomics. The aim is to provide a broad overview of established and emerging methodologies, the basic science behind these approaches and their utility from an industrial and medical perspective. The availability of the human genome and widespread use of micro array strategies for assessing specificity should make the meeting especially timely and provide a unifying focus by 2003. The latest advances on RNA interference, protein engineering to repress transcription, chemical approaches to gene control, antisense, ribozymes and knockout strategies will be discussed.

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

If your organization is interested in joining these entities in support of Keystone
Symposia, please contact:&nbspSarah Lavicka,
Director of Corporate Relations, Email: sarahl@keystonesymposia.org,Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.