Browse our KHDRBS1 Proteins (KHDRBS1)

On www.antibodies-online.com are 11 KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) Proteins from 7 different suppliers available. Additionally we are shipping KHDRBS1 Antibodies (131) and KHDRBS1 Kits (11) and many more products for this protein. A total of 164 KHDRBS1 products are currently listed.

These findings define a hitherto novel mechanism of action for Sam68 in governing p53 (show TP53 Proteins) transcriptional activation, and represent the first report of Sam68 in the regulation of tumor suppressor activities.

HNRNPL (show HNRNPL Proteins) acts as the adaptor to combine the two substructures and form the intact Sam68 nuclear body through the interaction of two sets of RNA recognition motifs with the putative architectural RNA in the respective substructures.

Sam68 was overexpressed in EOC tissue in association with such cancer malignant factors of FIGO stage, histological grade, and lymph node metastasis, and also positively regulated the proliferation of EOC cells.

This study identifies Sam68 as a key regulator of neural progenitor cell self-renewal and establishes a novel link between modulation of ALDH1A3 (show ALDH1A3 Proteins) expression and maintenance of high glycolytic metabolism in the developing cortex.

KHDRBS1 Protein Profile

Protein Summary

This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants.