Literature Discussion VI

Also, refer to chapter 14 and Gilbert website 14.3 for more
information on muscle development and the myogenic bHLH genes.

Your answers to the discussion questions should be in
complete sentences.

1.The authors
suggest that MyoR and capsulin have redundant functions.Propose a molecular model to explain
the functions of each of these two transcription factors in facial muscle
development in normal and in mutant mice.

2.Certain
head-specific muscles are lacking in the double mutant mice.Describe a model to explain the fate of
these facial muscle precursor cells in MyoR-/-; capsulin -/- mice.Did the authors provide any data to
support or refute this model?