If it is a terrifying thought that life is at the mercy of the multiplication of these minute bodies [microbes], it is a consoling hope that Science will not always remain powerless before such enemies...

If there is no solace in the fruits of our research, there is at least some consolation in the research itself. Men and women are not content to comfort themselves with tales of gods and giants, or to confine their thoughts to the daily affairs of life; they also build telescopes and satellites and accelerators and sit at their desks for endless hours working out the meaning of the data they gather.

In human freedom in the philosophical sense I am definitely a disbeliever. Everybody acts not only under external compulsion but also in accordance with inner necessity. Schopenhauers saying, that a man can do as he will, but not will as he will, has been an inspiration to me since my youth up, and a continual consolation and unfailing well-spring of patience in the face of the hardships of life, my own and others. This feeling mercifully mitigates the sense of responsibility which so easily becomes paralysing, and it prevents us from taking ourselves and other people too seriously; it conduces to a view of life in which humour, above all, has its due place.

Suppose that you are in love with a lady on Neptune and that she returns the sentiment. It will be some consolation for the melancholy separation if you can say to yourself at some possibly pre-arranged moment, She is thinking of me now. Unfortunately a difficulty has arisen because we have had to abolish Now. There is no absolute Now, but only the various relative Nows, differing according to their reckoning of different observers and covering the whole neutral wedge which at the distance of Neptune is about eight hours thick. She will have to think of you continuously for eight hours on end in order to circumvent the ambiguity Now.

We need a name for the new replicator, a noun that conveys the idea of a unit of cultural transmission, or a unit of imitation. 'Mimeme' comes from a suitable Greek root, but I want a monosyllable that sounds a bit like 'gene'. I hope my classicist friends will forgive me if I abbreviate mimeme to meme. If it is any consolation, it could alternatively be thought of as being related to 'memory', or to the French word mκme. It should be pronounced to rhyme with 'cream'.

[Cloning] can't make you immortal because clearly the clone is a different person. If I take twins and shoot one of them, it will be faint consolation to the dead one that the other one is still running around, even though they are genetically identical. So the road to immortality is not through cloning.

In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion.
(1987) -- Carl Sagan