We couple a deep understanding of our customers' needs with technology expertise to provide the quality solutions that our customers expect.

Clients

Transportation Security Administration

Content Management System

Overview

Implement a secure system to manage training materials (over 40GB
worth of security digital assets including document, video, audio, and
image files; system supports over 400,000 different digital assets) used
by U.S. airport and seaport security checkpoints

Scope

TConneX developed a full life-cycle system which was heavily customized to meet TSA security
requirements and integrated with TSA's web hosting system

Technologies

Oracle UCM and SSPU Publishing Module to automate publishing

Java, J2EE, Oracle Fusion Stack Architecture

LDAP, Identity Management

Load Balance and Clustered System technologies used

Enterprise Identity Management

Overview

Modernize the existing Enterprise Identity Management System to improve security and availability,
as well as take advantage of enhanced capabilities from new technologies.

Scope

Redesigned and upgraded the Identity Management System with multiple web nodes and implemented security module within web tier to enhance security, performance, and capacity.

Scope

Technologies

EMC Documentum

Integrated System with Java and .Net applications

Web Content Management System

Objective

Efficient management and control of content for both internal and external FDIC web sites, allowing the
end-user community to control the messages and documents presented without technical intervention.

Technologies

Oracle Web Center 11g

Oracle UCM 11g

Weblogic App Server

Java, J2EE Application

Identity Management System, LDAP

Ginnie Mae

Vital Records and Imaging Services

Objective

Outsource document imaging and management services to sustain vital records associated with mission essential
functions as part of a Continuity of Operations Plan (COOP) in compliance with National Archives and Records
Administration (NARA) and National Institute of Standards and Technology (NIST) directives.

Scope

Semantic digital scan of documents to enable keyword searching and database population

Secure Web-based remote access to documents

Perform on-going system Certification & Accreditation (C&A)

Technologies

Java

Java 2 Platform, Enterprise Edition (J2EE)

System developed and deployed on Infrastructure as a Service (IaaS) infrastructure

Nuclear Regulatory Commission

Program Support for the Office of International Programs

Objective

Provide logistics and technical support for NRC-sponsored knowledge training workshops and
seminars designed to assist international entities in developing effective regulatory
organizations and enforcing rigorous safety standards.

Scope

Program Management support, including overall financial management, for the educational programs.

Scope

Technologies

Clinical Data Interchange Standards Consortium (CDISC)

Study Data Tabulation Model (SDTM)

Analysis Dataset Model (ADaM)

SAS 9

Advanced Text Mining of Regulatory Documents Using NLP

Objective

In collaboration with CDER, TConneX uses NLP (Nature Language Processing) tool for the extraction, collection, storage, retrieval, analysis, and interpretation of regulatory science data from an array of CDER generated documents, and to archive or index the data using available standard dictionaries, nomenclature, and ontologies.

Scope

Apply NLP software to a substantial volume of documents in large scale and complex information environments to capture data and populate the extracted data into various databases.

Customize the NLP software to perform information extraction that identifies biologically meaningful semantic structures within free text using strategies based on Part-of-Speech information, ontologies or the identification of patterns.

Technologies

Objective

TConneX is developing a software tool capable of quantitative data mining of NLM MEDLINE literature database which contains 27 million medical citations to detect novel drug-adverse event (ADE) safety signals. This tool enables FDA to uniformly and systematically harness and analyze the information contained in published literature reports in a standardized manner to support drug safety surveillance and facilitate the performance of pharmacovigilance.

Scope

TConneX has collaborated with FDA CDER to develop PEARL, an innovative data mining tool to conduct a systematic analysis of the entire MEDLINE database for quantitative signal generation and signal management. The generated drug-adverse event signals are configured and visually displayed to permit FDA users to easily identify trends or patterns for specific drugs within and across the drug class and to understand the safety profile for a drug within the drug class.

The full production system will be scaled up so that the system can be utilized by up to 200 FDA medical officers and safety reviewers across several FDA CDER divisions including The Office of Surveillance and Epidemiology (OSE), and The Office of New Drugs (OND).

Technologies

Oracle

Java

D3

Empirica Study/WebSDM

Objective

To provide services for application and database upgrades, and maintenance of the current deployment of Empirica Study/WebSDM software (application and database) in all three environments (test/training, production, development).

Scope

Application software and database upgrades, patching and trouble-shooting, system maintenance and support

Upgrading the Empirica Study/WebSDM application and database to the currently approved Oracle release

Applying upgrades to application-associated COTS products in order to keep Empirica study/WebSDM current