To receive CME credit for this activity, participants must complete the post-test with a passing score of 80% and then complete the evaluation.

All fields are required.

E-mail:

Select the best answer to each question.

1.

Which of the following statements about the Vigen et al results is correct?

It was a prospective, open-label trial involving men from the US Department of Veterans Affairs (VA) hospital system

The Kaplan-Meier estimated event rates were 25.7% for the non-testosterone therapy group and 71.8% for the testosterone-therapy group

The raw data event rates were 21.2% for the non-testosterone therapy group and 10.1% for the testosterone therapy group

The absolute risk difference was 5.8%, favoring the non-testosterone therapy group

2.

Which of the following methodological errors confound interpretation of the data from the Vigen study?
A. More than 1000 men who received testosterone therapy after having an event were excluded from analysis
B. All men started in and contributed data to the non-testosterone therapy group. Statistical manipulation was applied to more than 50 variables
C. The final Kaplan-Meier estimate shows the opposite relationship to the raw data

A and B

B and C

A and C

A, B and C

None of the above

3.

The study by Vigen et al reported in the November 2013 issue of JAMA ______.

Did not evaluate cardiovascular risk

Agreed with prior literature that testosterone therapy does not increase cardiovascular risk