Table 6

Statistics of the pathway database comparison of core metabolic processes

Number of (percentage of union)

Genes

EC numbers

Metabolites

Reactions

union

1723

-55%

959

-32%

2805

-40%

3713

-47%

consensus

264 (15%)

+ 2%

180 (19%)

+ 1%

316 (11%)

+ 2%

144 (4%)

+ 1%

majority score

875 (51%)

+ 9%

508 (53%)

+ 3%

757 (27%)

+ 6%

674 (18%)

+ 4%

Database

Unique per database (percentage of union)

BiGG

75 (4%)

+ 3%

63 (7%)

+ 4%

276 (10%)

- 1%

621 (17%)

- 1%

EHMN

186 (11%)

+ 8%

125 (13%)

+ 7%

910 (32%)

+ 7%

1129 (30%)

+ 4%

HumanCyc

70 (4%)

-16%

62 (6%)

-15%

243 (9%)

- 7%

326 (9%)

- 4%

KEGG

180 (10%)

+ 8%

45 (5%)

+ 4%

209 (7%)

+ 1%

274 (7%)

+ 2%

Reactome

19 (1%)

- 3%

8 (1%)

0

80 (3%)

- 6%

154 (4%)

- 4%

Total

530 (31%)

+ 1%

303 (32%)

0

1718 (61%)

- 6%

2504 (67%)

- 3%

Genes: Entrez Gene IDs, including genes encoding for a component of a protein complex
as separate entities. EC numbers: only fully specified EC numbers. Metabolites: if
two metabolites of one database both match the same metabolite in another database
this is counted as one match. Reactions: reactions where not required to match on
e-, H+ and/or H2O. Differences with the outcomes of the global comparison (Table 3) are indicated
in percentages for each level of comparison.