The husband of Melbourne mother Karen Ristevski has been spotted leaving the couple's Melbourne home as footage has emerged of police conducting a re-enactment with what is believed to be the boutique owner's car.

Borce Ristevski, who police previously said is a suspect in his wife's murder, was seen driving away from the couple's home in Avondale Heights around 6.30am on Tuesday.

Borce refused to answer questions about the investigation into Karen's death, which appears to be heating up amid fresh developments.

It comes one day after police were seen driving a black Mercedes Coupe from the Ristevski's home reportedly in the direction of Mt Macedon, where her body was found, according to 7News.

The husband of Karen Ristevski was seen leaving the couple's Melbourne home on Tuesday as footage emerged of police examining what appears to be his wife's car (pictured)

Mystery: Karen Ristevski went missing last June. Borce Ristevski, on right, is the chief police suspect in her disappearance, his own lawyer said

Borce Ristevski, who police previously said is a suspect in his wife's murder, was seen driving away from the couple's home in Avondale Heights around 6.30am on Tuesday (pictured)

During the 'staged police activity', a police car followed the Mercedes as it headed back to the Ristevski home before being placed on a tow truck.

A witness working in the area snapped a picture of the car on the back of the tow truck and later told Radio 3AW the car was escorted by an unmarked police station wagon with flashing lights.

Karen's body was found wedged between two logs in bushland at Mount Macedon, north of the city, on February 20.