the beginner s guide to winning the nobel prize advice for young scientists

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Is it possible to be passionate about politics, football or R&B and still be a creative scientist? In this entertaining and inspiring account, Nobel Prize winner Peter Doherty offers readers an insider's guide into discovery science and the individuals who work in it. Starting with the story of his own career and its improbable origins in the outer suburbs of Brisbane, and its progression to a breakthrough discovery about how human immunity works. Doherty explores the realities of a life in science. How research projects are selected; how discovery science is resourced and organised; the big problems it is trying to solve; and the rewards and pitfalls of a career in scientific research: all these are explored in The Beginner's Guide to Winning the Nobel Prize. Doherty gives readers an insight into the issues that make him tick including his belief that the mission of science is to help make the world a better place to live in. He also essays answers to some of the great questions of our age. Are Nobel Prize winners exceptional human beings or just lucky? Are GMO crops really dangerous? And why can't scientists and born-again Christians get along?

In 1989 Michael Bishop and Harold Varmus were awarded the Nobel Prize for their discovery that normal genes under certain conditions can cause cancer. In this book, Bishop tells us how he and Varmus made their momentous discovery. More than a lively account of the making of a brilliant scientist, How to Win the Nobel Prize is also a broader narrative combining two major and intertwined strands of medical history: the long and ongoing struggles to control infectious diseases and to find and attack the causes of cancer. Alongside his own story, that of a youthful humanist evolving into an ambivalent medical student, an accidental microbiologist, and finally a world-class researcher, Bishop gives us a fast-paced and engrossing tale of the microbe hunters. It is a narrative enlivened by vivid anecdotes about our deadliest microbial enemies--the Black Death, cholera, syphilis, tuberculosis, malaria, smallpox, HIV--and by biographical sketches of the scientists who led the fight against these scourges. Bishop then provides an introduction for nonscientists to the molecular underpinnings of cancer and concludes with an analysis of many of today's most important science-related controversies--ranging from stem cell research to the attack on evolution to scientific misconduct. How to Win the Nobel Prize affords us the pleasure of hearing about science from a brilliant practitioner who is a humanist at heart. Bishop's perspective will be valued by anyone interested in biomedical research and in the past, present, and future of the battle against cancer. Table of Contents: List of Illustrations Preface 1. The Phone Call 2. Accidental Scientist 3. People and Pestilence 4. Opening the Black Box of Cancer 5. Paradoxical Strife Notes Credits Index Reviews of this book: Despite his book's encouraging title, Bishop--who won a Nobel Prize in Physiology and Medicine in 1989--cautions that "I have not written an instruction manual for pursuit of the prize." Instead, he has written an amiable reflection on the experience of being a Nobelist, intertwined with some history and anecdotes about the award, and balanced by a wide-ranging review of his own career as an "accidental scientist"...Along the way, Bishop reflects on the history of our knowledge of microbes, cancer, the politics of funding research and present-day disenchantment with science. His main purpose in writing this book, Bishop says, is to show that "scientists are supremely human"--which he does with grace and charm. --Publishers Weekly Reviews of this book: How to Win the Nobel Prize is typical Bishop: modest, funny, insightful and offering an extremely clear and brief explanation of the basic scientific achievement that won the 1989 Nobel Prize in physiology or medicine for himself and longtime colleague, Harold Varmus, now president of the Memorial Sloan-Kettering Cancer Center. --David Perlman, San Francisco Chronicle Reviews of this book: In these pages Bishop reveals himself as a good writer blessed with enviable clarity, someone sensible and levelheaded who likes people and is enamored of his science. --John Tyler Bonner, New York Times Book Review Reviews of this book: This is a treasure...Above all, How to Win the Nobel Prize is a civilised book and a lavishly rewarding one. --Roy Herbert, New Scientist Reviews of this book: At its heart this analysis of science and the scientific world is a jewel. How to Win the Nobel Prize is an inspirational book, full of careful analysis and judgement. --John Oxford, Times Higher Education Supplement Reviews of this book: Bishop is a gifted communicator and teacher, and he sets about his task of educating scientists and the public by describing his career in science and science politics...In the end, Bishop's book provides a road map for scientists and the public to build a robust scientific community that serves our society well. --Andreas Trumpp and Daniel Kalman, Nature Cell Biology J. Michael Bishop has written his book 'to show that scientists are supremely human.' The book is also a lucid explanation of how science has been harnessed to fight the human afflictions of cancer and infectious disease. And the story ends with a wide-ranging overview of today's challenges to the scientific enterprise. Overall, a must-read for all those interested in science and scientists--even those with absolutely no interest in winning a Nobel Prize! --Bruce Alberts, President, National Academy of Sciences J. Michael Bishop is that rare scientist who is widely read in literature and poetry. Most importantly, he remembers what he reads and thinks deeply about it, as well as about all else in his rich life. The Nobel Prize he won and richly deserved, his political activism, his understanding of cancer and microbiology, his devotion to the practice of science--all these provide fodder for his writerly craft. Quite a wonderful book! --David Baltimore, Nobel Laureate and President, California Institute of Technology

Santiago Ramón y Cajal was a mythic figure in science. Hailed as the father of modern anatomy and neurobiology, he was largely responsible for the modern conception of the brain. His groundbreaking works were New Ideas on the Structure of the Nervous System and Histology of the Nervous System in Man and Vertebrates. In addition to leaving a legacy of unparalleled scientific research, Cajal sought to educate the novice scientist about how science was done and how he thought it should be done. This recently rediscovered classic, first published in 1897, is an anecdotal guide for the perplexed new investigator as well as a refreshing resource for the old pro.Cajal was a pragmatist, aware of the pitfalls of being too idealistic -- and he had a sense of humor, particularly evident in his diagnoses of various stereotypes of eccentric scientists. The book covers everything from valuable personality traits for an investigator to social factors conducive to scientific work.

Though the word "pandemic" often conjures up an immediate vision of an appalling, acutely lethal and visually terrifying disease, in actuality, these really aren't the infections that we have to worry about when it comes to rapid, global spread. In Pandemics: What Everyone Needs to Know, Peter Doherty demystifies the Hollywood version of global infections and considers instead what pandemics really are, what situations encourage their spread, and which pathogens pose the greatest threat today. He also explains the various responses available to combat outbreaks and mitigate their effects, from the use of vaccines and drugs to quarantine.

From Nobel Prize-winning scientist James D. Watson, a living legend for his work unlocking the structure of DNA, comes this candid and entertaining memoir, filled with practical advice for those starting out their academic careers. In Avoid Boring People, Watson lays down a life’s wisdom for getting ahead in a competitive world. Witty and uncompromisingly honest, he shares his thoughts on how young scientists should choose the projects that will shape their careers, the supreme importance of collegiality, and dealing with competitors within the same institution. It’s an irreverent romp through Watson’s colorful career and an indispensable guide to anyone interested in nurturing the life of the mind. From the Trade Paperback edition.

The inside story of a quest to unlock one of cosmology’s biggest mysteries, derailed by the lure of the Nobel Prize. What would it have been like to be an eyewitness to the Big Bang? In 2014, astronomers wielding BICEP2, the most powerful cosmology telescope ever made, revealed that they’d glimpsed the spark that ignited the Big Bang. Millions around the world tuned in to the announcement broadcast live from Harvard University, immediately igniting rumors of an imminent Nobel Prize. But had these cosmologists truly read the cosmic prologue or, swept up in Nobel dreams, had they been deceived by a galactic mirage? In Losing the Nobel Prize, cosmologist and inventor of the BICEP (Background Imaging of Cosmic Extragalactic Polarization) experiment Brian Keating tells the inside story of BICEP2’s mesmerizing discovery and the scientific drama that ensued. In an adventure story that spans the globe from Rhode Island to the South Pole, from California to Chile, Keating takes us on a personal journey of revelation and discovery, bringing to vivid life the highly competitive, take-no-prisoners, publish-or-perish world of modern science. Along the way, he provocatively argues that the Nobel Prize, instead of advancing scientific progress, may actually hamper it, encouraging speed and greed while punishing collaboration and bold innovation. In a thoughtful reappraisal of the wishes of Alfred Nobel, Keating offers practical solutions for reforming the prize, providing a vision of a scientific future in which cosmologists may, finally, be able to see all the way back to the very beginning.

At the heart of this book by Nobel Prize–winning immunologist and professor Peter Doherty is this striking observation: Birds detect danger to our health and the environment before we do. Following a diverse cast of bird species around the world—from tufted puffins in Puget Sound to griffon vultures in India, pigeons in East Asia, and wedge-tailed shearwaters off the islands of Australia’s Great Barrier Reef—Doherty illuminates birds’ role as an early warning system for threats to the health of our planet and our own well-being. Their Fate Is Our Fate is an impassioned call not only to attention but to action. As “citizen scientists” we can collect data, vital to cutting-edge research, that depends on the birds that are all around us. Armed with our observations, scientists will continue to uncover new ways to glimpse our future in birds—and to affirm how, truly, their fate is our fate.

The inside story of a quest to unlock one of cosmology’s biggest mysteries, derailed by the lure of the Nobel Prize. What would it have been like to be an eyewitness to the Big Bang? In 2014, astronomers wielding BICEP2, the most powerful cosmology telescope ever made, revealed that they’d glimpsed the spark that ignited the Big Bang. Millions around the world tuned in to the announcement broadcast live from Harvard University, immediately igniting rumors of an imminent Nobel Prize. But had these cosmologists truly read the cosmic prologue or, swept up in Nobel dreams, had they been deceived by a galactic mirage? In Losing the Nobel Prize, cosmologist and inventor of the BICEP (Background Imaging of Cosmic Extragalactic Polarization) experiment Brian Keating tells the inside story of BICEP2’s mesmerizing discovery and the scientific drama that ensued. In an adventure story that spans the globe from Rhode Island to the South Pole, from California to Chile, Keating takes us on a personal journey of revelation and discovery, bringing to vivid life the highly competitive, take-no-prisoners, publish-or-perish world of modern science. Along the way, he provocatively argues that the Nobel Prize, instead of advancing scientific progress, may actually hamper it, encouraging speed and greed while punishing collaboration and bold innovation. In a thoughtful reappraisal of the wishes of Alfred Nobel, Keating offers practical solutions for reforming the prize, providing a vision of a scientific future in which cosmologists may, finally, be able to see all the way back to the very beginning.

To those interested in a life in science, Sir Peter Medawar, Nobel laureate, deflates the myths of invincibility, superiority, and genius; instead, he demonstrates it is common sense and an inquiring mind that are essential to the scientist’s calling. He deflates the myths surrounding scientists—invincibility, superiority, and genius; instead, he argues that it is common sense and an inquiring mind that are essential to the makeup of a scientist. He delivers many wry observations on how to choose a research topic, how to get along wih collaborators and older scientists and administrators, how (and how not) to present a scientific paper, and how to cope with culturally ”superior” specialists in the arts and humanities.

NEW YORK TIMES BESTSELLER The revolutionary book coauthored by the Nobel Prize winner who discovered telomerase and telomeres' role in the aging process and the health psychologist who has done original research into how specific lifestyle and psychological habits can protect telomeres, slowing disease and improving life. Have you wondered why some sixty-year-olds look and feel like forty-year-olds and why some forty-year-olds look and feel like sixty-year-olds? While many factors contribute to aging and illness, Dr. Elizabeth Blackburn discovered a biological indicator called telomerase, the enzyme that replenishes telomeres, which protect our genetic heritage. Dr. Blackburn and Dr. Elissa Epel's research shows that the length and health of one's telomeres are a biological underpinning of the long-hypothesized mind-body connection. They and other scientists have found that changes we can make to our daily habits can protect our telomeres and increase our health spans (the number of years we remain healthy, active, and disease-free). THE TELOMERE EFFECT reveals how Blackburn and Epel's findings, together with research from colleagues around the world, cumulatively show that sleep quality, exercise, aspects of diet, and even certain chemicals profoundly affect our telomeres, and that chronic stress, negative thoughts, strained relationships, and even the wrong neighborhoods can eat away at them. Drawing from this scientific body of knowledge, they share lists of foods and suggest amounts and types of exercise that are healthy for our telomeres, mind tricks you can use to protect yourself from stress, and information about how to protect your children against developing shorter telomeres, from pregnancy through adolescence. And they describe how we can improve our health spans at the community level, with neighborhoods characterized by trust, green spaces, and safe streets. THE TELOMERE EFFECT will make you reassess how you live your life on a day-to-day basis. It is the first book to explain how we age at a cellular level and how we can make simple changes to keep our chromosomes and cells healthy, allowing us to stay disease-free longer and live more vital and meaningful lives.