Blog Archives

Objectives: The apolipoprotein E (APOE) ε4 allele is an established risk factor for dementia, yet this genetic variant is associated with a mixed cognitive profile across the lifespan. This study undertakes both a systematic and meta-analytic review of research investigating APOE-related differences…

Possession of an APOE e4 allele is an established risk factor for Alzheimer’s disease, while the less commonly studied e2 variant is premised to offer some protection. This research explores the purported deleterious-protective dichotomy of APOE variants on attentional control in mid-adulthood. 66 volunteers,…

We all age, but why do some of us age better than others? This question is especially poignant for the field of cognitive ageing, with the prevalence of dementia rising each year. At the University of Sussex, the Ageing &…

On May 10th, Sussex Doctoral School hosted a symposium recognising the role of Apolipoprotein (APOE) in the development and progression of Alzheimer’s disease. Carrying an APOE e4 gene is established to increase the risk of Alzheimer’s disease in older adulthood, as well as…

Day 1 The themes of the 1st day of the main AD conference were Frontotemporal dementia, Neurovascular dysfunction, and Inflammation & Immunity. One of many fascinating presentations on this was given by Jessica Duncombe, a 3rd year PhD student from…

Professor Louise Serpell, co-Director of the Alzheimers Society DTC and the Dementia Reseearch Group won second prize at the Life Sciences Impact Day Bake-off with this wonderful Neuron Cake! Her kids ate most of the mitochondria…

I am a third-year medical student, currently visiting the Rusted lab group from Brazil to complete a summer research assistantship. As my goals are to become a clinical physician, working in the field of behavioural research is an area I…

Research in the Rusted Lab includes a study of the potential adverse side effects of hepatitis C treatment in HIV-positive individuals with a concurrent Hepatitis C infection – this is a condition that affects 40% of HIV patients. In these…

On February 14th and 15th, the Ageing and Dementia Group took their knowledge and favourite experimental tasks to Hove Park Upper School for the Bright Sparks Weekend. The Bright Sparks weekend included a variety of University groups and societies from…