OBGYN and Reproductive Services

Obstetrics, Gynecology and Reproductive Science Research

The strength of the Department of Obstetrics, Gynecology and Reproductive Science basic science research is that we combine scholarship with new clinical treatments to provide the best possible outcomes for our patients. From new approaches in cancer prevention and diagnosis to clinical trials, the critical research conducted at Mount Sinai has a long-tradition of dramatically improving the lives of our patients.

Since the early 1900's, our physicians and researchers have made seminal contributions to the field, including:

Led the international studies demonstrating that use of the drug Zidovudine could interrupt mother-to-child HIV transmission

Advanced the use of minimally invasive surgery in the treatment of benign and malignant gynecologic disease

Current Research Initiatives

A 5-year National Institutes of Health grant to study the different trimesters of pregnancy and their unique hormonal environments. Results from this study could change the way illness is managed in the pregnant patient, with the goal of improving outcomes through avoidance of hospitalizations and reduced miscarriage rates.

Clinical trials studying the use of vaccines for the prevention of cervical cancer and genital herpes

Clinical trial comparing the use of different chemotherapy agents in various stages of disease are being conducted in uterine and ovarian cancer. Mount Sinai trials also allow women with ovarian cancer access to Avastin (Bevacizumab) in combination with standard chemotherapy for first-line and second-line therapy.

Trials assessing the safe use of antiretroviral treatments for the prevention of mother-to-child HIV transmission

The clinical and scientific teams at the Icahn School of Medicine have been among the first to help women conceive using previously frozen eggs from egg donors, and our research teams continue to make advances in this emerging field. For women who must undergo potentially sterilizing chemotherapy or radiation therapy for cancer treatment, preserving eggs opens up the possibility of using their own genetic material to have a child after the disease has been treated. This also provides an exciting new possibility of fertility preservation for women who delay family-building.

Watch Video

Dr. Rhoda Sperling and her team of researchers at Mount Sinai are international leaders in the field of HIV infection and its impact on pregnancy.View Now