The ''Library of D.A. Zakythinos'' contains approximately 40.000 titles of books, pamphlets, periodicals, maps and audiovisual material. The periodicals collection numbers 1.100 titles while of equal importance is the collection of Greek printed material -books and pamphlets- as well as the microfilm collection where rare publications covering a wide spectrum of Hellenic bibliography from the 16th to the 19th centuries are preserved. From its very beginning the Library was enriched by donations offered by institutions, writers, scholars and bibliophiles. Special mention is due to the donations of Ioannis Sareyiannis (1962, 4.866 titles - closed collection), Alexandros Benakis (1979, 1.494 titles incorporated in the main collection) and Michael Stefanides (1995, 100 titles - closed collection).

The user may search for -mainly- Greek titles in the collection of the Library through the Internet, via a Web Interface in the address <http://argo.ekt.gr>, in the ''Special Libraries in Greece'' database hosted in the Web Server of the National Documentation Centre (NDC). The periodicals collection is also searchable in the same address, in the database of the Collective List of Periodicals of the NDC. The Library participates in the National Network of Scientific and Technological Libraries whose main activity is the online document ordering (of Xerox copies).