The program now includes support for Qualitative Glycopeptide Analysis, enabling users to resolve complex glycopeptides using data obtained from an LC-MS/MS run of proteolytically digested purified glycoproteins.

Further, enterococci with high level aminoglycoside resistance (HLAR), [beta]-lactamase production and glycopeptide resistance including vancomycin resistant enterococci (VRE) have emerged posing a therapeutic challenge to physicians due to the ease of acquiring and transferring antimicrobial drug resistance (11).

The patient cohort, accumulated over 129 international sites, was divided into two arms, with 547 patients receiving ceftobiprole (mean age 53 years) and 281 receiving the glycopeptide antibiotic vancomycin plus the third-generation cephalosporin ceftazidime (mean age 52 years), according to the researchers.

The DoH also yesterday published data on the infection glycopeptide resistant enterococci (GRE), which can cause infections of the blood and heart valves, but only three cases were reported in the North-East for 2004.

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