The Persian connection of the Indian churches has to bee seen in the context of the internal dissensions and state persecution of Christians in Persia from the 5th century. A Synod of the Persian Church (410 AD) affirmed the faith of Nicea and acknowledged the Metropolitan of Selucia-Ctesiphon as the Catholicos of East. Not long after, the christological controversies of Chaldeon, fuelled by the strains between the Persian and Byzantine empires, swayed the Persian church to declare itself "Nestroian" and its head to assume the title of Patariarch of the East (Babylon). From their base in the then flourishing theological school of Nisibis, Nestorian missionaries began moving to India, Central Asia, China and Ethiopia to teach their doctrines-probably associating the churches in these countries with the work of St. Thomas the Apostle, whom the Persians must have venerated as the founder of their own church.
By the 7th Century, specific references of the Indian church began to appear in Persian records. The Metropolitan of India and the Metropolitan of China are mentioned in the consecration records of Patriarches of the East. At one stage, however, the Indian church was claimed to be in the jurisdiction of the Metropolitan of Fars but this issue was settled by Patriarch Sliba Zoha (714- 728 AD) who recognized the traditional dignity of the autonomous Metropolitan of India.
There were other developments in the Persian Church of potential import to the Indian Church. A renaissance of the pre-Chalcedon faith began led by Jacob Baradeus, emphasizing the West Syrian Christological tradition of the one united nature, influencing the church in Persia as well. Availing the relatively favorable political climate following the Arab conquest of Syria and other parts of West Asia, a maphrianate of the anti-Chalcedonians was established and Mar Marutha, a native Persian, became the first Jacobite Maphriana (Catholicos) of the East. The jurisdiction of this Catholicos at Tigris extended to 18 episcopal diocesses in lower Mosopotamia and further east, but significantly, not to India.
On the growth of the church in India during the first 15 centuries, the balance of historical evidence and the thrust of local tradition point to its basic autonomy sustained by the core of its own faith and culture. It received with the trust and courtesy missionaries, bishops and migrants as they came from whichever eastern Church- Tigris or Babylon, Antioch or Alexandria, but not from the more distant Constantinopole or Rome. There were times in this long period when the Christians in India had been without a bishop and were led by an Arcdeacon. In such occasions requests were sent, sometimes with success, to one another of the Eastern prelates to help restore the episcopate in India. Meanwhile the church in Persia and much of west declined by internal causes and the impact of Islam, affecting both the "Nestorian" Patriarchate of the East (Babylon) and the Jacobite Catholicate of the East (Tigris). As will be seen from the later history of the Indian Church, the latter, was reestablished in India (Kottayam) in 1912 while the former was transplanted to America 1940.