Share This

To survive, animals must explore their world to find the necessities of life. It's a complex task, requiring them to form them a mental map of their environment to navigate the safest and fastest routes to food and water. They also learn to anticipate when and where certain important events, such as finding a meal, will occur.

Related Articles

Understanding the connection between these two fundamental behaviors, navigation and the anticipation of a reward, had long eluded scientists because it was not possible to simultaneously study both while an animal was moving.

In an effort to overcome this difficulty and to understand how the brain processes the environmental cues available to it and whether various regions of the brain cooperate in this task, scientists at UCLA created a multisensory virtual-reality environment through which rats could navigate on a trac ball in order to find a reward. This virtual world, which included both visual and auditory cues, gave the rats the illusion of actually moving through space and also allowed the scientists to manipulate the cues.

The results of their study, published in the current edition of the journal PLOS ONE, revealed something "fascinating," said UCLA neurophysicist Mayank Mehta, the senior author of the research.

The scientists found that the rats, despite being nocturnal, preferred to navigate to a food reward using only visual cues -- they ignored auditory cues. Further, with the visual cues, their legs worked in perfect harmony with their anticipation of food; they learned to efficiently navigate to the spot in the virtual environment where the reward would be offered, and as they approached and entered that area, their licking behavior -- a sign of reward anticipation -- increased significantly.

But take away the visual cues and give them only sounds to navigate, and the rats legs became "lost"; they showed no sign they could navigate directly to the reward and instead used a broader, more random circling strategy to eventually locate the food. Yet interestingly, as they neared the reward location, their tongues began to lick preferentially.

Thus, in the presence of the only auditory cues, the tongue seemed to know where to expect the reward, but the legs did not. This finding, teased out for the first time, suggests that different areas of a brain can work together, or be at odds.

"This is a fundamental and fascinating new insight about two of the most basic behaviors: walking and eating," Mehta said. "The results could pave the way toward understanding the human brain mechanisms of learning, memory and reward consumption and treating such debilitating disorders as Alzheimer's disease or ADHD that diminish these abilities."

Mehta, a professor of neurophysics with joint appointments in the departments of neurology, physics and astronomy, is fascinated with how our brains make maps of space and how we navigate in that space. In a recent study, he and his colleagues discovered how individual brain cells compute how much distance the subjects traveled.

This time, they wanted to understand how the brain processes the various environmental cues available to it. At a fundamental level, Mehta said, all animals, including humans, must know where they are in the world and how to find food and water in that environment. Which way is up, which way down, what is the safest or fastest path to their destination?

"Look at any animal's behavior," he said, "and at a fundamental level, they learn to both anticipate and seek out certain rewards like food and water. But until now, these two worlds -- of reward anticipation and navigation -- have remained separate because scientists couldn't measure both at the same time when subjects are walking."

Navigation requires the animal to form a spatial map of its environment so it can walk from point to point. An anticipation of a reward requires the animal to learn how to predict when it is going to get a reward and how to consume it -- think Pavlov's famous experiments in which his dogs learned to salivate in anticipation of getting a food reward. Research into these forms of learning has so far been entirely separate because the technology was not there to study them simultaneously.

So Mehta and his colleagues, including co-first authors Jesse Cushman and Daniel Aharoni, developed a virtual-reality apparatus that allowed them to construct both visual and auditory virtual environments. As video of the environment was projected around them, the rats, held by a harness, were placed on a ball that rotated as they moved. The researchers then trained the rats on a very difficult task that required them to navigate to a specific location to get sugar water -- a treat for rats -- through a reward tube.

The visual images and sounds in the environment could each be turned on or off, and the researchers could measure the rats' anticipation of the reward by their preemptive licking in the area of the reward tube. In this way, the scientists were able for the first time to measure rodents' navigation in a nearly real-world space while also gauging their reward anticipation.

"Navigation and reward consuming are things all animals do all the time, even humans. Think about navigating to lunch," Mehta said. "These two behaviors were always thought to be governed by two entirely different brain circuits, but this has never been tested before. That's because the simultaneous measurement of reward anticipation and navigation is really difficult to do in the real world but made possible in a virtual world."

When the rat was in a "normal" virtual world, with both sound and sight, legs and tongue worked in harmony -- the legs headed for the food reward while the tongue licked where the reward was supposed to be. This confirmed a long held expectation, that different behaviors are synchronized.

But the biggest surprise, said Mehta, was that when they measured a rat's licking pattern in just an auditory world -- that is, one with no visual cues -- the rodent's tongue showed a clear map of space, as if the tongue knew where the food was.

"They demonstrated this by licking more in the vicinity of the reward. But their legs showed no sign of where the reward was, as the rats kept walking randomly without stopping near the reward," he said. "So for the first time, we showed how multisensory stimuli, such as lights and sounds, influence multimodal behavior, such as generating a mental map of space to navigate, and reward anticipation, in different ways. These are some of the most basic behaviors all animals engage in, but they had never been measured together."

Previously, Mehta said, it was thought that all stimuli would influence all behaviors more or less similarly.

"But to our great surprise, the legs sometimes do not seem to know what the tongue is doing," he said. "We see this as a fundamental and fascinating new insight about basic behaviors, walking and eating, and lends further insight toward understanding the brain mechanisms of learning and memory, and reward consumption."

University of California - Los Angeles. (2013, November 6). Anticipation and navigation: Do your legs know what your tongue is doing?. ScienceDaily. Retrieved March 31, 2015 from www.sciencedaily.com/releases/2013/11/131106091410.htm

More From ScienceDaily

More Plants & Animals News

Featured Research

Mar. 31, 2015 — Researchers have recorded the first direct observations of the micro-scale mechanisms behind the ability of skin to resist tearing. The results could be applied to the improvement of artificial skin, ... full story

Mar. 31, 2015 — Soil organic matter, long thought to be a semi-permanent storehouse for ancient carbon, may be much more vulnerable to climate change than previously thought. Scientists have found that the common ... full story

Mar. 31, 2015 — Using the assessment tool ForWarn, US Forest Service researchers can monitor the growth and development of vegetation that signals winter's end and the awakening of a new growing season. Now these ... full story

Mar. 31, 2015 — Until now electric fences and trenches have proved to be the most effective way of protecting farms and villages from night time raids by hungry elephants. But researchers think they may have come up ... full story

Mar. 31, 2015 — The endangered desert pupfish has made itself at home in the harsh, hot environment of Death Valley hot springs by using a surprising evolutionary adaptation: They can go for up to five hours without ... full story

Mar. 31, 2015 — Researchers have detected a human fingerprint deep in the Borneo rainforest in Southeast Asia. Cold winds blowing from the north carry industrial pollutants from East Asia to the equator, with ... full story

Mar. 31, 2015 — A team of engineers and biologists reports new progress in using computer modeling and 3D shape analysis to understand how the unique grasping tails of seahorses evolved. These prehensile tails ... full story

Mar. 31, 2015 — As the five-year anniversary of the explosion of the Deepwater Horizon oil rig approaches, a new report looks at how twenty species of wildlife are faring in the aftermath of the ... full story

Mar. 31, 2015 — Scientists have uncovered the earliest fossilized evidence of an insect caring for its young. The findings push back the earliest direct evidence of insect brood care by more than 50 million years, ... full story

Giant Amphibian Fossils Found in Portugal

Reuters - Light News Video Online (Mar. 31, 2015) — Scientists discover a new species of giant amphibian that was one of the largest predators on earth about 220 million year ago. Tara Cleary reports.
Video provided by Reuters

Bionic Ants Could Be Tomorrow's Factory Workers

Reuters - Innovations Video Online (Mar. 30, 2015) — Industrious 3D printed bionic ants working together could toil in the factories of the future, says German technology company Festo. The robotic insects cooperate and coordinate their actions and movements to achieve a common aim. Amy Pollock reports.
Video provided by Reuters

Related Stories

Feb. 16, 2015 — Knowing where we are and remembering routes that we’ve walked are crucial skills for our everyday life. In order to identify neural mechanisms of spatial navigation, researchers analyzed the ... full story

Apr. 18, 2013 — A new study of brain rhythms in bats and rats challenges a widely-used model -- based on rodent studies -- of how animals navigate their environment. To get a clearer picture of processes in the ... full story

Aug. 23, 2011 — Men and women differ in the way they anticipate an unpleasant emotional experience, which influences the effectiveness with which that experience is committed to memory, according to new ... full story

ScienceDaily features breaking news and videos about the latest discoveries in health, technology, the environment, and more -- from major news services and leading universities, scientific journals, and research organizations.