I Am Legend (2007)

BIOTERRORBIBLE.COM: Starting in 1957, there have been 18 mainstream movies and documentaries dealing specifically
with bio-terror and pandemics. Although these films have been sporadic over the
last 55 years, they have intensified over the last 10 and appear to be peaking
in 2012 or 2013.

Warner Bros. began developing I Am Legend in 1994, and various actors and directors were attached to the project, though production was delayed due to budgetary concerns related to the script. Production began in 2006 in New York City, filming mainly on location in the city, including a $5 million scene[3] at the Brooklyn Bridge, the most expensive scene ever filmed in the city at the time.

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Neville's daily routine includes experimenting on infected rats to find a cure for the virus and trips through a decaying Manhattan to collect supplies or hunt for deer. He keeps vigil each day for a response to his continuous recorded AM radio broadcasts, which instruct any survivors to meet him at midday at the South Street Seaport. Neville's isolation is broken only by the companionship of his German Shepherd Samantha and interaction with mannequins he has set up as patrons of a video store.

When one of his rat experiments shows a promising treatment, Neville sets a snare trap and captures an infected woman. An enraged Darkseeker alpha male attempts to rescue her, but is driven back by the sunlight. In the laboratory in his heavily fortified Washington Square Park home, Neville tries the new serum on the infected woman, seemingly without success.

The next day, after finding one of his mannequins ("Fred") out in the street in front of Grand Central Terminal,
he is caught in a snare trap and passes out. He regains consciousness
at dusk and frees himself, but he is attacked by a pack of infected
dogs. Although Neville and Sam kill the dogs, one of the infected dogs
bites Sam during the fight. Neville brings Sam home and attempts to save
the dog by injecting a strain of his serum, but it is too late; a
heartbroken Neville is forced to kill his only companion.

Overcome by grief and rage, Neville attacks a group of the infected
on the seaport the following night with his UV-light-equipped SUV. He
manages to kill several Darkseekers, but they overwhelm and nearly kill
him before he is rescued by a pair of immune humans, a woman named Anna (Alice Braga) and a boy named Ethan (Charlie Tahan),
who followed his radio broadcasts. Anna and Ethan take him back to his
home. Anna explains that they are making their way to a survivors' camp
in Bethel, Vermont. Neville disputes that such a camp exists, and expresses his doubt when Anna says God told her about it.

The following night, the alpha male leads a mob of Darkseekers in an
attack on the house. Anna, who was unaware of Neville's precautions in
covering his scent outside the house, inadvertently allowed the
Darkseekers to follow their trail. When the Darkseekers charge the
house, Neville stops the first wave of Darkseekers with claymore mines,
but finds himself defenseless against the second wave. As Neville tries
to find Anna and Ethan, a Darkseeker enters and attacks him. The
Darkseeker retreats upstairs and begins tearing a hole in the roof so
other infected can get in.

After Neville saves Anna and Ethan, they retreat into the basement laboratory. They seal themselves in a reinforced plexiglass
room with the infected woman, and they discover that Neville's
treatment is now working: the subject looks much more human. The
infected break in and the alpha male starts throwing himself against the
plexiglass, cracking the material. Realizing that the last treatment
had been successful, Neville draws a vial of the infected woman's blood
and gives it to Anna before shutting them inside a coal chute in the
back of the lab. He uses an M67 hand grenade
to wipe out the attackers at the cost of his own life. Anna and Ethan
are later seen stopping at the gated entrance to the survivors' colony,
where Anna hands over the antidote. In a voice-over, Anna claims that the survivors are Neville's legacy, as his fight for a cure became legend.

Alternate EndingSeveral scenes were altered before the film's release, especially the
stand-off between Neville and the infected in his laboratory. In the
original ending, the alpha male makes a butterfly-shaped smear on the
glass. Neville realizes that the alpha male is identifying the woman he
was experimenting on by a butterfly tattoo, and that the alpha male
wants her back. Neville puts his gun down and returns the infected
woman. Neville and the alpha male then exchange stares; Neville
apologizes to the Darkseekers; the alpha male acknowledges his apology,
and the infected leave. The final shot follows Neville, Anna, and Ethan
as they drive away towards Vermont with the antidote.[5]

According to visual effects supervisor Janek Sirrs: "At that point,
Neville's — and the audience's — assumptions about the nature of these
creatures are shown to be incorrect. We see that they have actually
retained some of their humanity. There is a very important moment
between the alpha male and Neville" (Wikipedia, 2012).