Head-to-head comparisons of medication uses, side effects, ratings, and more.

Oxycontin (oxycodone) treats moderate to severe pain, but can be habit-forming, especially if used long-term.

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3.8/ 5 average rating with 1241 reviewsforoxycodone

Treats moderate to severe pain.

Percocet (Oxycodone / Acetaminophen) is the strongest prescription combination pain medicine for as needed pain relief, but make sure you don't take too much acetaminophen (Tylenol) to avoid liver problems or death.

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3.8/ 5 average rating with 1399 reviewsforPercocet

Upsides

Oxycontin (oxycodone) is available in a tamper-resistant form to lessen the risk of abuse.