HealthDay News — For patients with prior percutaneous coronary intervention (PCI), perioperative aspirin seems to be beneficial, according to a study published online November 13 in the Annals of Internal Medicine.

Michelle M. Graham, MD, from the University of Alberta in Canada, and colleagues performed a subgroup analysis of a multicenter trial to assess data for adults age ≥45 years who had or were at risk for atherosclerotic disease and were undergoing noncardiac surgery; 4,998 patients in the overall trial and 234 participants in the subgroup analysis received aspirin therapy, while 5,012 patients in the overall trial and 236 in the subgroup analysis received placebo initiated within four hours before surgery.