Interaction Information:

Comment

As shown in HeLa cells, assays in BMMs (bone marrow derived macrophages) determined that the three different BlaM-effector fusions (CBU0077, CBU1823 and CBU1524 (caeA)) were translocated during infection by C. burnetii. In BMMs there were a small number of translocation-positive cells detected at four hours post-infection for all three effector proteins, which suggests that the Dot/Icm system is activated sooner following uptake by BMMs.

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