Original Article :

Author :

Siti Nurkasanah*1

Chatarina Umbul Wahyuni*2

Arief Wibowo*3

Mahasiswa Fakultas Kesehatan Masyarakat

Dosen Fakultas Kesehatan Masyarakat

Dosen Fakultas Kesehatan Masyarakat

Abstract :

ABSTRACT
Leprosy Serologic studies conducted by Leprosy Laboratory Institute of Tropical Disease (ITD), Airlangga University Surabaya in SDN Sumberaji Lamongan in 2007 found 45.8% of patients had subclinical leprosy and serum all survey respondents are still stored in the ITD. The purpose of this study was to analyze factors that influence the increase in specific antibody titers in patients with subclinical leprosy in the Sumberaji village in Lamongan. The method used is use observational analytic with cross sectional study. The research sample number 41 children with leprosy specific antibody IgM titer ≥ 600 U/ml of examination results 2007. Studied variables such as age, sex, BCG immunization, nutrition, natural lighting, residential density, parental knowledge, parental income, contact history, personal hygiene and water used. To determine the effect of the variable to the rise in IgM leprosy antibody titers of specific statistical tests used Multiple Logistic Regression. From the results of serology of leprosy (indirect ELISA) in samples that get results IgM of leprosy specific antibody titers increased as much as 41.46% (17 samples). From the results of multiple logistic regression statistical analysis results obtained effect of natural lighting and nutritional status (BMI) to the increase in IgM of leprosy specific antibody titer.
Keywords: IgM, antibodies specific leprosy, ELISA