Vern Schramm, Ph.D., professor and chair of biochemistry at Einstein, discusses drug development for a wide range of diseases -- including T-cell leukemia, gout, malaria and autoimmune disorders -- based on his research in transition state analogues. Dr. Schramm, who holds the Ruth Mearns Chair in Biochemistry, also talks about his childhood in South Dakota and what influenced him to become interested in chemistry. This edition of Einstein On, a research and medicine podcast, is hosted by Gordon Earle, associate dean for communications and public affairs. (March 20, 2012)