Cure possible for CML? Chronic myeloid leukemia

"There are a number of approaches for selective targeting of leukemic stem cells(LSCs). These include targeting stem-cell properties, such as self-renewal,inducing cycling of quiescent LSCs to sensitize them to conventional agents,employing or inducing immune-based mechanisms, and targeting tumor-specificphysiology. Agents such as parthenolide inhibit the ability of leukemic stemcells to respond to oxidative stress and make leukemic stem cells and bulkleukemic cells susceptible to cell death, while normal stem cells remainrelatively unharmed by these agents. The major mechanism of action of thesesmall molecules appears to revolve around the aberrant glutathione metabolismpathway found in leukemic cells." Extract of How close are we to targeting the leukemia stem cell? by Best Practice & Research Clinical Haematology