BioPAX pathway converted from "PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane" in the Reactome database.PI4P is dephosphorylated to PI by SACM1L at the Golgi membranePI4P is dephosphorylated to PI by SACM1L at the Golgi membraneThis event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>Reactome DB_ID: 18062171Golgi membraneGO00001391-phosphatidyl-1D-myo-inositol 4-phosphate [ChEBI:17526]1-phosphatidyl-1D-myo-inositol 4-phosphateReactomehttp://www.reactome.orgChEBI17526Reactome DB_ID: 293721cytosolGO0005829phosphate(3-) [ChEBI:18367]phosphate(3-)ChEBI18367Reactome DB_ID: 152414611-phosphatidyl-1D-myo-inositol [ChEBI:16749]1-phosphatidyl-1D-myo-inositolChEBI16749PHYSIOL-LEFT-TO-RIGHTACTIVATIONReactome DB_ID: 9947817UniProt:F1PJF2SACM1LCanis familiarisNCBI Taxonomy9615UniProtF1PJF2Chain Coordinates1EQUAL587EQUALGO0034596GO molecular functionReactome Database ID Release 729947826Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9947826Reactome Database ID Release 729947828Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=9947828ReactomeR-CFA-16761331Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=R-CFA-1676133.1At the Golgi membrane, phosphatidylinositide phosphatase SAC1 (SACM1L) efficiently dephosphorylates phosphatidylinositol 4-phosphate (PI4P), and to a lesser extent phosphatidylinositol 3-phosphate (PI3P), to phosphatidylinositol (PI). No significant activity of this enzyme towards phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) was detected (Rohde et al. 2003).14527956Pubmed2003The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complexRohde, HMCheong, FYKonrad, GPaiha, KMayinger, PBoehmelt, GJ Biol Chem 278:52689-99inferred by electronic annotationIEAGOIEA