Princess Jellyfish is about an 18-year-old girl named Tsukimi (sounds like zucchini), who lives in Tokyo, Japan, and has a strong interest in everything about jellyfish. Tsukimi became inspired by them due to her late mother, who showed her the tenticly creatures in an aquarium when Tsukimi was a little girl. Living in an all-female dorm, whom all share the quality of being “otakus”, or nerds, she eventually meets a cross-dresser, where his true gender is only known by Tsukimi.