Both my wife and I both run Adium nightly build v.1.6hgr5946 (installed ages ago to solve issues with Yahoo connectivity). I'm running it under Mac OS 10.9.5 without issue. My wife, however, is running it under Mac OS 10.12.6 and experiences Adium crashing multiple times throughout the day.

Is there some known or possible incompatibility between that version of Adium and 10.12.6?

In speaking with my wife more about this, it turns out that Adium doesn't actually crash. The app stays up. It just disconnects itself, and she has to reconnect to the network. We're both on the same XMPP service (Koderoot) and I never have disconnects. The only difference between our setups is the Mac OS version we're running.