Figure 6

Determination of the expression of ARRDC3 related mRNA/miRNA under A administration. (A) RT-PCR show that the mRNA levels of ARRDC3, PPP1R3C and Sfpq were increased by Aβ administration in primary cultured cortical neurons of Tg6799 mice. (B) Real time PCR show that the expression levels of miR139-5p and miR3470a were not significantly altered by Aβ administration in primary cortical neurons from Tg6799 mice. (C) Luciferase activity of ARRDC3 promoter increased after Aβ treatment in LM cortical neurons but not in MT neurons.