New Delhi: Researchers have said that IVF-based technique that reduces the risk of debilitating genetic disorders from being passed from mother to children is safe. Scientists reported an in-depth analysis of human embryos created using the new technique designed to reduce the risk of mothers passing on mitochondrial disease to their children, which is debilitating and often life-limiting. Mitochondrial disease is a chronic, genetic disorder that occurs when the mitochondria of the cell fail to produce enough energy for cell or organ function, according to MitoAction, a US-based organisation working to improve quality of life for adults and children affected by the disease.