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Growth Differentiation Factor 2 ELISA Kits (GDF2)

On www.antibodies-online.com are 72 Growth Differentiation Factor 2 (GDF2) ELISA Kits from 13 different suppliers available. Additionally we are shipping GDF2 Antibodies (82) and GDF2 Proteins (20) and many more products for this protein. A total of 179 GDF2 products are currently listed.

These results suggest that BMP9-transduced calvarial mesenchymal progenitor cells seeded in a PPCN-g thermoresponsive scaffold is capable of inducing bone formation in vivo and is an effective means of creating tissue engineered bone for critical sized defects.

the data identify MxA (show MX1 ELISA Kits) as a novel stimulator of BMP4 (show BMP4 ELISA Kits) and BMP9 transcriptional signaling, and suggest it to be a candidate IFN-alpha (show IFNA ELISA Kits)-inducible mechanism that might have a protective role against development of pulmonary arterial hypertension and other vascular diseases.

BMP9 inhibited the proliferation and migration of the A549 cells.

his study shows that BMP9 inhibition is associated with Osteosarcoma (OS) development and that enhanced expression of BMP9 may be a potential treatment method for OS

Our findings provide a clearer understanding of the cellular pathways utilized by BMP-9 for chondrogenesis that may help improve current therapies for regenerative cartilage repair.

Constitutive expression of low levels of BMP-9 stabilises hepatocyte function in the healthy liver. High levels of BMP-9 cause enhanced damage upon acute or chronic injury.

Notch (show NOTCH1 ELISA Kits) signaling may play an important role in BMP9-induced osteogenesis and angiogenesis. It's conceivable that simultaneous activation of the BMP9 and Notch (show NOTCH1 ELISA Kits) pathways should efficiently couple osteogenesis and angiogenesis of MSCs for successful bone tissue engineering.

he results of the present study demonstrated that BMP9 promoted the osteoclast differentiation of osteoclast precursors via binding to the ALK1 (show ACVRL1 ELISA Kits) receptor on the cell surface, and inhibiting the ERK1/2 (show MAPK1/3 ELISA Kits) signaling pathways in the cell

Data show athat beta-catenin (show CTNNB1 ELISA Kits) can be activated by bone morphogenetic protein 9 (BMP9) and the activation of beta-catenin (show CTNNB1 ELISA Kits) plays an important role in the differentiation of C3H10T1/2 cells into cardiomyocyte-like cells induced by BMP9.

We have established a producer line that stably expresses a high level of active BMP9 protein. Such producer line should be a valuable resource for generating biologically active BMP9 protein for studying BMP9 signaling

GDF2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons.