These health claims have not been yet tested in clinical trials on humans. Even within the practice of Ayurvedic medicine, there are controversies about the composition (amlaki, haritaki and bibhitaki), preparation, and medicinal uses of Triphala.[5]

There is preliminary evidence that Triphala contains compounds with antioxidant properties in isolated cells and rats, but this has not yet been demonstrated in people.[6][8][9][10] Triphala has significant immunostimulatory effects on cellular immune response, especially cytotoxicT cells and natural killer cells.[11] Triphala extract significantly prevents selenite-induced experimental cataractogenesis in vitro and in vivo for rats.[12]