The year is 1963. A brilliant sicentist in his twenties, Bruce David Banner, creates a serum that can regenerate muscle tissue. Aiding him is Betty Ross, his fiancee. Her adopted father, General Michael Ross(he found Betty when she was a toddler in the ruins of Berlin, at the end of the Second World War, and took her back to America), hears about this and sees how it can benefit the soldiers under his command. He tricks Bruce and Betty into believing that they would be modifying the serum to increase human strength and resistance to infections or viruses. Banner realises that only gamma radiation will unlock the serum's full potential, so he injects some of his own creation into himself and exposes himself to a high dose of gamma rays for several seconds. At first, there doesn't appear to be any change in Bruce, but this changes when Betty realises the real reason behind her adopted father's interest in their work and informs her husband-to-be. The two of them confront General Ross and an argument between the two men escalates Bruce's temper, which triggers an incredible transformation from a normal man to a fifteen-foot tall, green-skinned creature that possesses phenomonal strength - the Hulk! Realising the harm he can do, he flees, but General Rosss now sees Banner's strange condition as having huge benefit for the US Army, and makes it business to track down Bruce, wherever he may run to.....