In 1935, Indiana Jones arrives in India, still part of the British Empire, and is asked to find a mystical stone. He then stumbles upon a secret cult committing enslavement and human sacrifices in the catacombs of an ancient palace.

In 1938, after his father Professor Henry Jones, Sr. goes missing while pursuing the Holy Grail, Professor Henry "Indiana" Jones, Jr. finds himself up against Adolf Hitler's Nazis again to stop them from obtaining its powers.

In 1957, archaeologist and adventurer Dr. Henry "Indiana" Jones, Jr. (Harrison Ford) is called back into action and becomes entangled in a Soviet plot to uncover the secret behind mysterious artifacts known as the Crystal Skulls.