Abstract: Mistletoe of the genus Tapinanthus(Loranthaceae) is a stem hemiparasite causing damage on citruses and guava trees in central Sudan. The objectives of this study were: to evaluate the distribution, incidence, , severity and host range of the parasite. Surveys were conducted in 20102013 in four States along the Blue Nile banks in an area extended about 492 km. Results indicated that the parasite is widely distributed along the Blue Nile banks from Al-Rusayris (12ْ 21' 4" N and 34ْ 22' 14" E) to Hisahisa (14 44' 47" N and 33° 17' 43" E). The highest incidence of the parasite (69%) occurred in Blue Nile State, followed by Sinar state (66.3%) with highest incidence (100%) reported in Singa Province. While Kamlin province (Northern Gezira state) and Khartoum state were seemed to be free from the parasite. The highest percentage of mistletoe infection was found on lime (Citrus aurantifoliaSwingle ) and guava (Psidiumguajava M.) in Western and Eastern Sinar, respectively, with disease severity index range between 74.2%- 90.6% in both localities. The parasitic weed appears to have a wide host range, attacking 22 species belonging to 14 families. The most affected trees were citruses, guava and Ziziphusspina-chriti. In conclusion the results reflects the epidemic situation of mistletoe along the Blue Nile banks, despite the lack of quantitative data concerning losses in fruit production of infected plants. It also revealed that mistletoe could parasitize a variety of host plants, with special preference of potential suitable hosts.