Proteus Syndrome is a condition which involves atypical growth of the bones, skin, head and a variety of other symptoms.
Proteus syndrome was first identified by Michael Cohen Jr., DMD, PhD., in
1979. The name comes from the greek God Proteus who used to change his
shape or form to avoid capture. it is a very rare, variable and progressive
condition, affecting more males than females. The cause of Proteus syndrome
is unknown. The syndrome became more widely known when it was determined
that Joseph Merrick (the patient depicted in the play and movie "The
Elephant Man") had severe Proteus syndrome rather than Neurofibromatosis as
had been suggested previously.

What are the signs of Proteus Syndrome

Overgrowth, asymmetry and gigantism of the limbs

Increased size of an organ, or the body, or bones (Hypertrophy)

Raised rough skin (verrucous epidermal naevi)

Deep lines and overgrowth of soft tissue on the soles of the feet (cerebriform connective tissue nevus)