The action-buddy comedy is described as being in the vein of Butch Cassidy and the Sundance Kid and centers on two women living as bandits in a futuristic, post-apocalyptic America. It’s Always Sunny in Philadelphia‘s Kaitlin Olson will lead the voice, cast as Ordwood Cassius, a hard-drinking, quick-thinking, fast-talking bullshitter who has more debts than sense. Lake Bell (Childrens Hospital, Unsupervised) will voice Shopcarter Clay, the fastest gun in the post-apocalyptic South who doesn’t go looking for trouble but shares a station wagon with it. Susan Sarandon (Lifetime’s upcoming Secret Life of Marilyn Monroe) is set as Connie Mack, the ruthless and cutthroat owner of Wilke’s only saloon and brothel. Mack runs the booze, the girls and effectively the whole town. Olson, Bell and Sarandon are set as series regulars should the pilot move forward.

Other guest voices set to participate include JB Smoove as Doc Benz, the town’s only doctor, locked in a dysfunctional, co-dependent relationship with Smiffy (who carts the Doc’s ornery, legless ass around). Kevin Michael Richardson (The Cleveland Show, Teenage Mutant Ninja Turtles, animated Guardians of the Galaxy) will play Smiffy, the enormous blacksmith, a gentle giant who can fix anything so long as Doc says it’s OK. Jeffrey Tambor (Transparent) will voice Waitstill Weeks, the utterly powerless and disregarded mayor of Wilke, who’s barely in charge of his own newspaper, which only he reads.

Stephen Root (King of the Hill) will play Preacher, a chubby, good-natured man of God. Katy Mixon (Mike & Molly) will play “sister-whores” Jack Ruby and Lee Harvey. Robert Patrick (Scorpion) will play Reever Grint, the terrifying tax-collector from Richway — he’s the crookedest of all the crooked sheriffs.