NucleoTrap resin is a spherical silica matrix in aqueous suspension. Because of the uniformity of the silica particles, even large DNA fragments (<20 kb) are safe from shearing and degradation.

The NucleoTraPCR PCR purification kit contains a modified matrix that cannot bind fragments smaller than 100 bp. It is ideal for separating PCR products from primers, primer-dimers, and free nucleotides after PCR is completed. Each 10 µl of suspension can extract 6 µg of DNA.