NIHPROVIDER RESTRICTIONS: HUES line recipients must provide documentation of ESCRO (or equivalent ethical) review for the research planned with the requested lines to Harvard University. NIH RESTRICTIONS: NIH-funded research with this line is limited to research consistent with the following language from the informed consent document: "These cells will be used to study the embryonic development of endoderm with a focus on pancreatic formation. The long-term goal is to create human pancreatic islets that contain ß cells, the cells that produce insulin, for transplantation into diabetics."

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