Oxazolidinone Antibiotics Drug Class

Oxazolidinone Antibiotics are one of the newest forms of antibiotics. They interfere with the synthesis of protein thus inhibiting the growth of bacteria. It is not yet known the where the exact location the drug binding site and the action of oxazolidinone takes place. Most people use the photoreactive panel derivatives to be able to identify where the site of action that oxazolidinones take place in the human cell and bacterial ribosome. This experiment shows a cross link data that the position of oxazolidinone molecule found in the binding site located in the peptidyl transferase center (PTC). There were oxazolidinones that interacted with the A of the ribosome instead of interfering with having Aminocyl-tRNA placement. There are cross links of oxazolidinones to rRNa in the human cells; this takes place in the PTC of mitochondrial but not in the cytoplasmic ribosome.

Oxazolidinone Antibiotics Drugs

Oxazolidinone Antibiotics Uses

Oxazolidinone Antibiotics are used to fight bacteria that are found in the body. It is used to treat different kind of bacterial infections like skin infection, pneumonia, and infections that resist other antibiotics. Oxazolidinone Antibiotics have mechanism of action that is different from other antibiotics. This is the reason that it can be used even on the toughest bacteria. It stops the growth of bacteria by binding it to bacterial protein synthesis. This results in a fold of eight increased potency.

This drug tends to act as initial inhibitor of bacterial protein. It binds 23S RNA ribosomal of the 50S subunit. This prevents 70S from being formed initiation complex, as well as amino-acetyl docking. This is the reason that it is regarded as a strong antibiotic; it deals with even the toughest of bacteria.

Oxazolidinone Antibiotics Side Effects

The major side effects of Oxazolidinone Antibiotics are

gastrointestinal

nausea

vomiting

diarrhea

headache

discoloration of the tongue

The side effects that are serious tend to result in discontinuation of this medication. These side effects are thrombocytopenia bleeding of the gastrointestinal and hemoglobin levels being low.

Oxazolidinone Antibiotics Interactions

Oxazolidinone Antibiotics are used to fight bacteria that are found in the body. It is used to treat different kind of bacterial infections like skin infection, pneumonia, and infections that resist other antibiotics. Oxazolidinone Antibiotics have mechanism of action that is different from other antibiotics. This is the reason that it can be used even on the toughest bacteria. It stops the growth of bacteria by binding it to bacterial protein synthesis. This results in a fold of eight increased potency.

This drug tends to act as initial inhibitor of bacterial protein. It binds 23S RNA ribosomal of the 50S subunit. This prevents 70S from being formed initiation complex, as well as amino-acetyl docking. This is the reason that it is regarded as a strong antibiotic; it deals with even the toughest of bacteria.

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