This study aimed to examine the effects of informal caregivers on the functioning of older adults in home health care (HHC). The authors performed a secondary data analysis using the Outcome and Assessment Information Set of older adults (N = 8,750) who were admitted to a HHC agency from acute care hospitals. We conducted hierarchical multiple linear regression with functional dependence after a 60-day episode of formal HHC as an outcome variable. The older adults with informal caregivers showed less functional dependence at discharge (β = -0.821, p = .027) than those without informal caregivers. Older adults who have a spouse (β = -3.886, p < .001), offspring (β = -3.614, p < .001), relative (β = -4.360, p < .001), or nonrelative (β = -4.977, p < .001) caregiver showed less functional dependence at discharge compared with those who had a paid caregiver when controlling for risk factors.