Abstract

Following on from our "Nanotechnology for Drug Delivery" series of reports we
are turning the focus onto medical diagnostics with our latest report:
"Nanotechnology for Medical Diagnostics"

Nanotech enabled medical diagnostics promise to improve just about everything
that can be improved from a diagnostics point of view: earlier detection of
disease, higher sensitivity, higher accuracy, higher throughput capability,
more results per assay; time saving and cost-effectiveness.

As with our "Nanotechnology for Drug Delivery" series of reports, this
report provides a market numbers for the nanotech enabled medical diagnostic
market between 2000-2010 and a market forecast for the period 2011-2021.

Report Scope

Two sets of data are presented in this report:

The TAM growth for NMBD between 2000-2010;

TAM forecast for NMBD between 2011- 2021.

Both sets of data are segmented into;

TAM (US$ millions, % share, and CAGR) for:

America

Asia (key economies)

Europe (key economies)

RoW (key economies)

Technology type (US$ millions, % share and CAGR) for;

Main Technological Approaches:

Quantum dots (QDs);

Gold nanoparticles;

Cantilevers;

Exosomes;

Nanobiosensors;

Main Technological Applications:

Nanotechnology-based medical and biomedical imaging for diagnostics;

Nanotechnology-based medical devices for diagnostics;

Nanotechnology in Early Disease Detection.

Geographical Scope

The studied regions are:

North America:

USA;

European Union (27):

Germany;

France;

UK;

Other Countries of EU;

Russian Federation

Asia:

India;

Japan;

P. R. China;

South Korea (R. of Korea);

Taiwan;

RoW

Quantifying the Total Addressable Market (TAM) Current

The TAM for nanotech enabled diagnostics is estimated to be 2.439 US$ Billion
(end of 2011).

Nanotechnology applied to medical imaging and gold nanoparticles for diagnosis
were the application and technology respectively, with the highest growth
during the last decade, currently (2011 figures) at:

Medical Imaging: 1.7 Billion US$

Gold Nanoparticles: 959 Million US$

While the US, China and Germany were the countries with the highest growth
currently (2011 figures) at:

North America: 675 Million US$

China: 330 Million US$

Germany: 117 Million US$

Forecast

We forecast the TAM for nanotech enabled diagnostics to reach $53.6B in 2021.
In comparison our report "Nanotechnology for Drug Delivery" forecasts a TAM of
$136B in 2021 for nanotech enabled drug delivery.

In 2021, Asia (China, Japan, South Korea, Taiwan, India combined) tops the
list with the highest TAM, China and India are neck and neck for CAGR.

Of all the technologies studied for this report, exosomes for diagnosis show
the highest CAGR between 2011-2021 while medical imaging remains the highest
growth application of the nanotech enabled diagnostics market in 2021.

APPENDIX

List of Figures

CHAPTER ONE

Formula for the calculation of the Compound Annual Growth Rate (CAGR)
[2].

Exhibit 1.2

Formula for the verification of the calculated values of CAGR
(2011-2021) [2].

Exhibit 1.3

Metres in a nanometre (top), nanometres in a metre (bottom)

CHAPTER TWO

Exhibit 2.1

Illustration of the fact that the periodic table of elements, as we know
it (at meter scale) governed by classic Newtonian laws of physics. However,
when perceived at nanoscale, those elements are governed by the laws of
quantum physics.

Exhibit 2.2

Proportion of the population aged over 65 and over 80 [8].

CHAPTER THREE

Exhibit 3.1

Key barriers to the adoption of nanotechnology in medicine and
biomedicine (Source: Cientifica, Ltd.).

Exhibit 3.2

Specified expected barriers in the development of particular types of
nanoparticles (Courtesy of CienNanoroadmap Synthesis Report), [6].

Line chart representing the Total Addressable Market, TAM forecast to
2021 (for the 2011-2021 period), for nanotechnology in medical and
biomedical diagnostics, without segmentation, source: Cientifica (all
figures US$ Million Dollars).

CHAPTER FOUR

Exhibit 4.1

Summarized comparison of characteristics of quantum dots (QDs),
cantilevers and gold nanoparticles in the scope of the adoption of
nanotechnology to clinical diagnosis [3].

Exhibit 4.2

Schematic diagram representing the general structure of a Quantum dot
(in this case, a typical CdSe/ZnS QD). The coating extremities can change
according to requirements regarding application and biocompatibility (e.g.
mercaptoacetic acid or streptavidin) [3].

Exhibit 4.3

A schematic diagram of a multiplex QD-based assay. Multiple antigens
(Ag) can be labelled through the use of primary antibodies (Ab) conjugated
to QDs with different sizes. One antibody may be biotinylated and detected
with a streptavidin-coated QD. On excitation, QDs will have different
emission maxima based on their sizes [3].

3-D pie chart representing the Total Addressable Market, TAM in 2010,
for nanotechnology in medical and biomedical diagnostics, by world regions
and countries, source: Cientifica (all figures in percentage).

Exhibit 4.10

Horizontal bar graph representing the Total Addressable Market, TAM in
2010, for nanotechnology in medical and biomedical diagnostics, by world
regions and countries, source: Cientifica (all figures US$ Million Dollars).

Exhibit 4.11

Line chart representing the Total Addressable Market, TAM (2000-2010),
for nanotechnology in medical and biomedical diagnostics, by world regions
and countries, source: Cientifica (all figures US$ Million Dollars).

3-D stacked area chart representing the Total Addressable Market, TAM
(2000-2010), for nanotechnology in medical and biomedical diagnostics, by
world regions and countries, source: Cientifica (all figures US$ Million
Dollars).

Exhibit 4.14

3-D pie chart representing the Total Addressable Market, TAM in 2010,
for nanotechnology in medical and biomedical diagnostics, all world regions
and countries studied, source: Cientifica (all figures in percentage).

Exhibit 4.15

Horizontal bar graph representing the Total Addressable Market, TAM in
2010, for nanotechnology in medical and biomedical diagnostics, all world
regions and countries studied, source: Cientifica (all figures US$ Million
Dollars).

3-D pie chart representing the Total Addressable Market, TAM in 2010,
for nanotechnology in medical and biomedical diagnostics, technological
approaches as a whole, source: Cientifica (all figures in percentage).

Exhibit 4.33

Horizontal bar graph representing the Total Addressable Market, TAM in
2010, for nanotechnology in medical and biomedical diagnostics,
technological approaches as a whole, source: Cientifica (all figures US$
Million Dollars).

Exhibit 4.34

Line chart representing the Total Addressable Market, TAM (2000-2010),
for nanotechnology in medical and biomedical diagnostics, technological
approaches as a whole, source: Cientifica (all figures US$ Million Dollars).

3-D pie chart representing the Total Addressable Market, TAM in 2010,
for nanotechnology in medical and biomedical diagnostics, technological
applications as a whole, source: Cientifica (all figures in percentage).

Exhibit 4.38

Horizontal bar graph representing the Total Addressable Market, TAM in
2010, for nanotechnology in medical and biomedical diagnostics,
technological applications as a whole, source: Cientifica (all figures US$
Million Dollars).

Exhibit 4.39

Line chart representing the Total Addressable Market, TAM (2000-2010),
for nanotechnology in medical and biomedical diagnostics, technological
applications as a whole, source: Cientifica (all figures US$ Million
Dollars).

3-D pie chart representing the Total Addressable Market, TAM in 2010,
for nanotechnology in medical and biomedical diagnostics, impact of early
disease detection, source: Cientifica (all figures in percentage).

Exhibit 4.43

Horizontal bar graph representing the Total Addressable Market, TAM in
2010, for nanotechnology in medical and biomedical diagnostics, impact of
early disease detection, source: Cientifica (all figures US$ Million
Dollars).

Exhibit 4.44

Line chart representing the Total Addressable Market, TAM (2000-2010),
for nanotechnology in medical and biomedical diagnostics, impact of early
disease detection, source: Cientifica (all figures US$ Million Dollars).

3-D pie chart representing the Total Addressable Market, TAM forecast in
2021, for nanotechnology in medical and biomedical diagnostics, by world
regions, source: Cientifica (all figures in percentage).

Exhibit 4.49

Horizontal bar graph representing the Total Addressable Market, TAM
forecast in 2021, for nanotechnology in medical and biomedical diagnostics,
by world regions, source: Cientifica (all figures US$ Million Dollars).

Exhibit 4.50

Line chart representing the Total Addressable Market, TAM forecast by
2021 (for the 2011-2021 period), for nanotechnology in medical and
biomedical diagnostics, by world regions, source: Cientifica (all figures
US$ Million Dollars).

3-D stacked area chart representing the Total Addressable Market, TAM
forecast by 2021 (for the 2011-2021 period), for nanotechnology in medical
and biomedical diagnostics, by world regions, source: Cientifica (all
figures US$ Million Dollars).

Exhibit 4.53

3-D pie chart representing the Total Addressable Market, TAM forecast in
2021, for nanotechnology in medical and biomedical diagnostics, by all world
regions / countries studied, source: Cientifica (all figures in percentage).

Exhibit 4.54

Horizontal bar graph representing the Total Addressable Market, TAM
forecast in 2021, for nanotechnology in medical and biomedical diagnostics,
by all world regions / countries studied, source: Cientifica (all figures
US$ Million Dollars).

Exhibit 4.55

Line chart representing the Total Addressable Market, TAM forecast by
2021 (for the 2011-2021 period), for nanotechnology in medical and
biomedical diagnostics, by all world regions / countries studied, source:
Cientifica (all figures US$ Million Dollars).

Line chart representing the Total Addressable Market, TAM forecast by
2021 (for the 2011-2021 period), for nanotechnology in medical and
biomedical diagnostics, technological approaches as a whole, source:
Cientifica (all figures US$ Million Dollars).

Line chart representing the Total Addressable Market, TAM forecast by
2021 (for the 2011-2021 period), for nanotechnology in medical and
biomedical diagnostics, technological applications as a whole, source:
Cientifica (all figures US$ Million Dollars).

Line chart representing the Total Addressable Market, TAM forecast by
2021 (for the 2011-2021 period), for nanotechnology in medical and
biomedical diagnostics, impact of early disease detection, source:
Cientifica (all figures US$ Million Dollars).

3-D stacked area chart representing the Total Addressable Market, TAM
forecast by 2021 (for the 2011-2021 period), for nanotechnology in medical
and biomedical diagnostics, impact of early disease detection, source:
Cientifica (all figures US$ Million Dollars).

Exhibit 4.89

SWOT analysis to evaluate the strengths, weaknesses, opportunities and
threats involved in nanotechnology in medical and biomedical diagnostics, in
the scope of the technology adoption roadmap (during the 2011-2021 period).

APPENDIX

Exhibit A.1

Table of the top 20 organizations showing the highest publishing
activity in PubMed periodicals (2000-2010), based on PubMed, for
Nanotechnology in Drug Delivery. World Region: North America; country: USA.

Organizations are ordered first by descending order of total articles
published and then ordered alphabetically (increasing order), if applicable.

Exhibit A.2

Table of the top 20 organizations showing the highest publishing
activity in PubMed periodicals (2000-2010), based on PubMed, for
Nanotechnology in Drug Delivery. World Region: European Union; country:
Germany.

Organizations are ordered first by descending order of total articles
published and then ordered alphabetically (increasing order), if applicable.

Exhibit A.3

Table of the top 20 organizations showing the highest publishing
activity in PubMed periodicals (2000-2010), based on PubMed, for
Nanotechnology in Drug Delivery. World Region: European Union; country:
France.

Organizations are ordered first by descending order of total articles
published and then ordered alphabetically (increasing order), if applicable.

Exhibit A.4

Table of the top 20 organizations showing the highest publishing
activity in PubMed periodicals (2000-2010), based on PubMed, for
Nanotechnology in Drug Delivery. World Region: European Union; country: UK.

Exhibit A.5

Table of the organizations with publishing activity in PubMed
periodicals (2000-2010), based on PubMed, for Nanotechnology in Drug
Delivery. Country: Russian Federation.

Organizations are ordered alphabetically (increasing order).

Exhibit A.6

Table of the top 20 organizations showing the highest publishing
activity in PubMed periodicals (2000-2010), based on PubMed, for
Nanotechnology in Drug Delivery. World Region: Asia; country: India.

Organizations are ordered first by descending order of total articles
published and then ordered alphabetically (increasing order), if applicable.

Exhibit A.7

Table of the top 20 organizations showing the highest publishing
activity in PubMed periodicals (2000-2010), based on PubMed, for
Nanotechnology in Drug Delivery. World Region: Asia; country: India.

Organizations are ordered first by descending order of total articles
published and then ordered alphabetically (increasing order), if applicable.

Exhibit A.8

Table of the top 20 organizations showing the highest publishing
activity in PubMed periodicals (2000-2010), based on PubMed, for
Nanotechnology in Drug Delivery. World Region: Asia; country: Japan.

Organizations are ordered first by descending order of total articles
published and then ordered alphabetically (increasing order), if applicable.

Exhibit A.9

Table of the top 20 organizations showing the highest publishing
activity in PubMed periodicals (2000-2010), based on PubMed, for
Nanotechnology in Drug Delivery. World Region: Asia; country: P R China.

Organizations are ordered first by descending order of total articles
published and then ordered alphabetically (increasing order), if applicable.

Exhibit A.10

Table of the top 20 organizations showing the highest publishing
activity in PubMed periodicals (2000-2010), based on PubMed, for
Nanotechnology in Drug Delivery. World Region: Asia; country: South Korea
(Republic of Korea).

Organizations are ordered first by descending order of total articles
published and then ordered alphabetically (increasing order), if applicable.

Exhibit A.11

Table of the organizations with publishing activity in PubMed
periodicals (2000-2010), based on PubMed, for Nanotechnology in Drug
Delivery. Asia; country: Taiwan.