<p id="desc-first">Methodologies to apply DNA for building precisely controlled nanostructures have greatly developed over the recent years. Our focus for BIOMOD is to utilize DNA to make a shell like structure which can capture molecules inside the shell-like body, as if a shellfish is eating its prey. Entrapment of the substrate was detected by the numerous florescent molecules that are attached to the body. This research may become a foundation for using DNA to mimic catalytic activity of enzymes.</p>

<p id="desc-first">Methodologies to apply DNA for building precisely controlled nanostructures have greatly developed over the recent years. Our focus for BIOMOD is to utilize DNA to make a shell like structure which can capture molecules inside the shell-like body, as if a shellfish is eating its prey. Entrapment of the substrate was detected by the numerous florescent molecules that are attached to the body. This research may become a foundation for using DNA to mimic catalytic activity of enzymes.</p>

Methodologies to apply DNA for building precisely controlled nanostructures have greatly developed over the recent years. Our focus for BIOMOD is to utilize DNA to make a shell like structure which can capture molecules inside the shell-like body, as if a shellfish is eating its prey. Entrapment of the substrate was detected by the numerous florescent molecules that are attached to the body. This research may become a foundation for using DNA to mimic catalytic activity of enzymes.

fig2.

Medical functions such as detection of diseases with small amount of blood are possible by using microfluidics. For example, detecting and sensing the concentration of Thrombin which causes blood coagulation is possible by using Shell and microfluidics developed by our team. In the future, we will develop medical DNA Shell system for monitoring components of blood, detecting diseases, inputting medicine by DNA Shell, computing system integrated in microfluidics.

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Motives

Design

Result

In this section, we write about the result of our experiment. We can classify the experiment that we performed roughly into four themes:

Assembly of the DNA Shell

Capturing Ability

Immobilizing on microfluidic device

Supporting Enzyme

We describe the part which I was able to confirm by each experiment.

Method

Future Work

We aim to make a device that has wider usage than an enzyme.
By putting together DNA Shell, certain target substances, and an enzyme, you can bring functionality or selectivity to the enzyme.
It will become possible thanks to the diversity of DNA Shell.