As the health care industry works toward the widespread adoption of electronic health records by 2014, nursing must transformitself as a profession in order to make full use of the capabilities electronic recordswill provide. This will require changes in nursing education and nursing practice to make informatics competencies part of every nurse’s skill set. It will require nursing organizations to work toward a shared vision. Above all, it will demand that the profession be actively involved in advancing the national health care information technology (IT) agenda and the vision of patient-centered, knowledge- based care targeted by that agenda.