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alterations in cell

is alterations in cell

one of the major fluid compartment. Usually denotes all body fluid outside the cells

metabolism

is the set of life-sustaining chemical transformations within the cells of organisms. the three main purposes of metabolism are the conversion of food/fuel to energy to run cellular processes

intracellular fluid

the remainder and one of the major fluid compartment.

lethal

are alleles that cause the death of the organism that carry them. They are usually a result of mutations in genes that are essential to growth or development

stimulus

a thing or event that evokes a specific functional reaction in an organ or tissue:

accumulate

gradually gather or acquire (resulting a whole)

delineated

describe or portray (something) precisely

noxious

harmful poisonous or very unpleasant

atmospheric pressure gradients

the pressure gradient (typically of air, more generally of any fluid) is a physical quantity that describes which direction and at what rate the pressure changes the most rapidly around a particular location

microcirculation

circulation of the blood in the smallest blood vessels, present in the vasculature embedded within organ tissues. This contrasts with macrocirculation, which is the circulation of blood to and from the organs.

hypoxia

the causes decreased perfusion of blood to the tissues, inadequate oxygen in blood. effect is disturbance of cellular metabolism.

toxic metabolite

foreign substance enter the body, blood stream, and the liver. However, when some substances are metabolized, the resulting metabolites are toxic to the body and can cause the fatal results.

secrete

of a cell, gland, or organ. Produce or discharge a substance

perfusion

in physiologic perfusion is the process of body delivering blood to the capillary bed in biologic tissue.The word is derived from the French verb "perfuser" meaning to "pour over or through."

somatic death

is the complete and irreversible stoppage in circulation, respiration, and brain functions

metabolite acidosis

is a condition that occurs when the body produces excessive quantities of acid or when the kidneys are not removing enough acid from the body

excessive

more than is necessary, normal, or desirable; immoderate

immoderate

not sensible or restrained

histamine

is involved in the inflammatory response and has a central role as a mediator of itching. As part of an immune response to foreign pathogens, histamine is produced by basophils and by mast cells found in nearby connective tissues.

radical

(especially of change or action) relating to or affecting the fundamental nature of something; far-reaching or thorough

excretion

Excretion is the process by which waste products of metabolism and other non-useful materials are eliminated from an organism

proximal

situated nearer to the center of the body or the point of attachment

susceptible

likely or liable to be influenced or harmed by a particular thing

deterioration

the process of becoming progressively worse

speculated

form a theory or conjecture about a subject without firm evidence

convoluted

extremely complex and difficult to follow. And intricately folded, twisted, or coiled

exogenous

caused by an agent or organism outside the body. common to get by inhalation of organic carbon particles that are generated by burning fossil fuels

atrophied

waste away, typically due to the degeneration of cells, or become vestigial during evolution

interstitial fatty infliltration

a condition that occurs with obesity. Fat cells accumulate between the parenchymal cells of an organ, probably as a result of the transformation of interstitial consecutive tissue cells into fat cells.

lipid peroxidation

produce this which are unstable and break down to produce aldehydes and organic free radicals. This becomes a self-propagating interaction that can cause widespread membrane damage.

Reperfusion injury

has been increasingly noted and studied in ischemic tissue that has been reperfused with activated oxygen.

antioxidants

an antioxidant is a molecule that inhibits the oxidation of other molecules. Antioxidants such as thiols or ascorbic acid terminate these chain reactions

glycogenoses

disorder; results from specific enzyme deficiencies.

endogenous

(produced whithin the body) probably like exogenous

anthracosis

these particles accumulate in the macrophages and lymph nodes of the lung tissue, producing blackened appearance of the lungs

lipofuscin

pigmentation of the skin is common in the aging person. It is made up of golden brown granules

melanin

is a black-brown pigment that is formed by the melanocytes of the skin. Protect against sun rays. The amount of melanin imparts the degree of color to the skin