PHILADELPHIA - Two important veterans left the Philadelphia Eagles' practice Thursday with injuries.

Left tackle Jason Peters left the field after injuring a quadriceps muscle during a run play. Safety Malcolm Jenkins walked off after injuring his hamstring.

Neither player returned to practice. The Eagles didn't announce anything about the severity of the injuries.

Peters' injury causes concern because of his history. Last season, Peters missed two games and parts of several others. The team listed his injury as a quadriceps injury, but Peters said the pain in his thigh muscle was actually caused by a pinched nerve in his back.

It was not clear Thursday whether this injury was related to last year's injury. Matt Tobin replaced Peters as the first-team left tackle.

Jenkins has not missed a game in his two seasons with the Eagles. The problem in this case is the lack of depth at the safety position. With Jenkins out, Ed Reynolds moved up to first-team safety.

Reynolds, a fifth-round draft choice in 2014, has been on the Eagles' practice squad each of the past two years. He was on the active roster for the last seven games of the 2015 season. He appeared in six games, starting the final three.

"Malcolm's a really good player," Eagles defensive coordinator Jim Schwartz said. "We need the guys behind him to step up. Those guys have not been consistent."

The Eagles were without right guard Brandon Brooks, who has an injured hamstring, and running back Ryan Mathews, who has an ankle injury.

ESPN's Adam Caplan reported that rookie defensive lineman Connor Wujciak had shoulder surgery Wednesday and could be out for the entire season.