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I'd suggest using msconfig to disable it. Note using msconfig is not without risk, so do so carefully.

With the disclaimer out of the way...1. Click the start button, click run and type msconfig and hit enter2. Go to the startup tab and find "readericon45G" and uncheck the checkbox3. Do not make any other changes!4. Click OK and restart if prompted.

That should stop it running.

I'm speculating that all that it does is display an appropriate icon when you insert a memory card and not having it running shouldn't have any negative effects on your system. If it does you can just repeat the steps above and recheck the checkbox.