Duloxetine may also be used for purposes not listed in this medication guide.

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capsule, green, imprinted with 20 mg, LILLY 3235

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capsule, blue/white, imprinted with Lilly 3240, 30 mg

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capsule, green, imprinted with TEVA, 7542

000937543_PB

capsule, blue/white, imprinted with TEVA, 7543

000937544_PB

capsule, blue/green, imprinted with TEVA, 7544

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capsule, blue, imprinted with 2890

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capsule, blue/gray, imprinted with LOGO 2891, LOGO 2891

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capsule, green, imprinted with X, 01

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capsule, blue/white, imprinted with X, 02

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capsule, blue/green, imprinted with X 03

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capsule, yellow, imprinted with B, 746

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capsule, green/white, imprinted with B, 747

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capsule, brown/green, imprinted with B, 748

Cymbalta 20 mg

capsule, green, imprinted with 20 mg, LILLY 3235

Cymbalta 30 mg

capsule, blue/white, imprinted with Lilly 3240, 30 mg

Cymbalta 60 mg

capsule, blue/yellow, imprinted with Lilly 3237, 60 mg

Duloxetine DR 20 mg 231550654

capsule, clear/green, imprinted with LOGO, 007

Duloxetine DR 20 mg 317220581

capsule, green, imprinted with H, 190

Duloxetine DR 20 mg 435470379

capsule, white, imprinted with 557, 20mg

Duloxetine DR 30 mg 317220582

capsule, blue/white, imprinted with H, 191

Duloxetine DR 30 mg 435470380

capsule, green/white, imprinted with 558, 30mg

Duloxetine DR 30 mg231550655

capsule, clear/white, imprinted with LOGO, 008

Duloxetine DR 40 mg 681800297

capsule, white, imprinted with LU, H25

Duloxetine DR 60 mg 002282892

capsule, gray/white, imprinted with LOGO 2892, LOGO 2892

Duloxetine DR 60 mg 231550656

capsule, blue/clear, imprinted with LOGO, 009

Duloxetine DR 60 mg 317220583

capsule, blue/green, imprinted with H, 192

Duloxetine DR 60 mg 435470381

capsule, blue/white, imprinted with 559, 60mg

Duloxetine ER 20 mg 683820385.JPG

capsule, green/white, imprinted with 241, 20 mg

Duloxetine ER 30 mg 683820386.JPG

capsule, blue/green, imprinted with 242, 30 mg

Duloxetine ER 60 mg 683820387.JPG

capsule, blue/white, imprinted with 243, 60 mg

What are the possible side effects of duloxetine (Cymbalta, Irenka)?

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

Do not stop using duloxetine without first talking to your doctor.

What should I discuss with my healthcare provider before taking duloxetine (Cymbalta, Irenka)?

You should not use duloxetine if you are allergic to it.

Do not take duloxetine within 5 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. A dangerous drug interaction could occur.

Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraineheadaches, serious infections, or prevention of nausea and vomiting. These medicines may interact with duloxetine and cause a serious condition called serotonin syndrome.

Duloxetine is not approved for use by anyone younger than 7 years old.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Taking duloxetine during pregnancy may cause breathing problems, feeding problems, seizures, or other complications in the newborn baby. However, you may have a relapse of depression if you stop taking this medicine. Tell your doctor right away if you become pregnant. Do not start or stop taking this medicine without your doctor's advice.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of duloxetine on the baby.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

How should I take duloxetine (Cymbalta, Irenka)?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Taking duloxetine in higher doses or more often than prescribed will not make it more effective, and may increase side effects.

Swallow the capsule whole and do not crush, chew, break, or open it.

You may take duloxetine with or without food.

It may take up to 4 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

What happens if I overdose (Cymbalta, Irenka)?

What should I avoid while taking duloxetine (Cymbalta, Irenka)?

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Dizziness or fainting can cause falls, accidents, or severe injuries.

What other drugs will affect duloxetine (Cymbalta, Irenka)?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can affect duloxetine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information (Cymbalta, Irenka)?

Your pharmacist can provide more information about duloxetine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.