Yeah I've had this issue with both Crysis and Warhead, I have yet to find a fix. I use Alt-Enter to put it in window mode when the mouse isn't aligned and then set it back to full screen. It's faster then attempting to click on the misaligned invisible buttons. If it doesn't start full screen I just toggle it.

I was getting messed up triangles around the player when I change suit mode with 177.66 and very messed up triangles all over the place when using the binoculars just like I used to get in FarCry with 177.92

And they still say "Lost Contact" after they've just killed you!!! But thats not really a driver issue but a stupidity issue with Crytek.