Inhalation:Inhalation may cause irritation of the upper
respiratory tract. Symptoms of overexposure may include fatigue, confusion,
headache, dizziness and drowsiness. Peculiar skin sensations (e. g. pins and
needles) or numbness may be produced. Very high concentrations may cause
unconsciousness and death. Ingestion:Swallowing may cause
abdominal spasms and other symptoms that parallel over-exposure from
inhalation. Aspiration of material into the lungs can cause chemical
pneumonitis, which may be fatal. Skin Contact:Causes
irritation. May be absorbed through skin. Eye Contact:Causes
severe eye irritation with redness and pain. Chronic Exposure:Reports of chronic poisoning describe anemia, decreased blood cell count
and bone marrow hypoplasia. Liver and kidney damage may occur. Repeated or
prolonged contact has a defatting action, causing drying, redness, dermatitis.
Exposure to toluene may affect the developing fetus. Aggravation of
Pre-existing Conditions:Persons with pre-existing skin disorders or
impaired liver or kidney function may be more susceptible to the effects of
this substance. Alcoholic beverage consumption can enhance the toxic effects
of this substance.

4. First Aid Measures

Inhalation:If inhaled, remove to fresh air. If not
breathing, give artificial respiration. If breathing is difficult, give
oxygen. CALL A PHYSICIAN IMMEDIATELY. Ingestion:Aspiration
hazard. If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water.
Never give anything by mouth to an unconscious person. Get medical attention
immediately. If vomiting occurs, keep head below hips to prevent aspiration
into lungs. Skin Contact:In case of contact, immediately flush
skin with plenty of soap and water for at least 15 minutes while removing
contaminated clothing and shoes. Wash clothing before reuse. Call a physician
immediately. Eye Contact:Immediately flush eyes with plenty of
water for at least 15 minutes, lifting lower and upper eyelids occasionally.
Get medical attention immediately.

5. Fire Fighting Measures

Fire:Flash point: 7C (45F) CCAutoignition
temperature: 422C (792F)Flammable limits in air % by volume: lel: 3.3;
uel: 19Flammable liquid and vapor!Dangerous fire hazard when exposed
to heat or flame. Vapors can flow along surfaces to distant ignition source
and flash back. Explosion:Above flash point, vapor-air
mixtures are explosive within flammable limits noted above. Contact with
strong oxidizers may cause fire or explosion. Sensitive to static discharge.
Fire Extinguishing Media:Dry chemical, foam or carbon dioxide.
Water may be used to flush spills away from exposures and to dilute spills to
non-flammable mixtures. Special Information:In the event of a
fire, wear full protective clothing and NIOSH-approved self-contained
breathing apparatus with full facepiece operated in the pressure demand or
other positive pressure mode. Water spray may be used to keep fire exposed
containers cool.

6. Accidental Release Measures

Ventilate area of leak or spill. Remove all sources of ignition.
Wear appropriate personal protective equipment as specified in Section 8.
Isolate hazard area. Keep unnecessary and unprotected personnel from entering.
Contain and recover liquid when possible. Use non-sparking tools and
equipment. Collect liquid in an appropriate container or absorb with an inert
material (e. g., vermiculite, dry sand, earth), and place in a chemical waste
container. Do not use combustible materials, such as saw dust. Do not flush to
sewer! If a leak or spill has not ignited, use water spray to disperse the
vapors, to protect personnel attempting to stop leak, and to flush spills away
from exposures. US Regulations (CERCLA) require reporting spills and releases
to soil, water and air in excess of reportable quantities. The toll free
number for the US Coast Guard National Response Center is (800) 424-8802.

J. T. Baker SOLUSORB(R) solvent adsorbent is recommended for spills of
this product.

7. Handling and Storage

Protect against physical damage. Store in a cool, dry
well-ventilated location, away from any area where the fire hazard may be
acute. Outside or detached storage is preferred. Separate from incompatibles.
Containers should be bonded and grounded for transfers to avoid static sparks.
Storage and use areas should be No Smoking areas. Use non-sparking type tools
and equipment, including explosion proof ventilation. Containers of this
material may be hazardous when empty since they retain product residues
(vapors, liquid); observe all warnings and precautions listed for the product.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits:Toluene: - OSHA
Permissible Exposure Limit (PEL):200 ppm (TWA); 300 ppm (acceptable
ceiling conc.); 500 ppm (maximum conc.).- ACGIH Threshold Limit Value
(TLV):50 ppm (TWA) skin, A4 - Not Classifiable as a Human Carcinogen.
Ventilation System:A system of local and/or general exhaust is
recommended to keep employee exposures below the Airborne Exposure Limits.
Local exhaust ventilation is generally preferred because it can control the
emissions of the contaminant at its source, preventing dispersion of it into
the general work area. Please refer to the ACGIH document, Industrial
Ventilation, A Manual of Recommended Practices, most recent edition, for
details. Personal Respirators (NIOSH Approved):If the exposure
limit is exceeded, a half-face organic vapor respirator may be worn for up to
ten times the exposure limit or the maximum use concentration specified by the
appropriate regulatory agency or respirator supplier, whichever is lowest. A
full-face piece organic vapor respirator may be worn up to 50 times the
exposure limit or the maximum use concentration specified by the appropriate
regulatory agency or respirator supplier, whichever is lowest. For emergencies
or instances where the exposure levels are not known, use a full-face piece
positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators
do not protect workers in oxygen-deficient atmospheres. Skin
Protection:Wear impervious protective clothing, including boots,
gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:Use chemical safety goggles and/or a full face
shield where splashing is possible. Maintain eye wash fountain and
quick-drench facilities in work area.

12. Ecological Information

Environmental Fate:When released into the soil, this
material may evaporate to a moderate extent. When released into the soil, this
material is expected to leach into groundwater. When released into the soil,
this material may biodegrade to a moderate extent. When released into water,
this material may evaporate to a moderate extent. When released into water,
this material may biodegrade to a moderate extent. When released into the air,
this material may be moderately degraded by reaction with photochemically
produced hydroxyl radicals. When released into the air, this material is
expected to have a half-life of less than 1 day. This material is not expected
to significantly bioaccumulate. This material has a log octanol-water
partition coefficient of less than 3.0. Bioconcentration factor = 13.2 (eels).
Environmental Toxicity:This material is expected to be toxic
to aquatic life. The LC50/96-hour values for fish are between 10 and 100 mg/l.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be
handled as hazardous waste and sent to a RCRA approved incinerator or disposed
in a RCRA approved waste facility. Processing, use or contamination of this
product may change the waste management options. State and local disposal
regulations may differ from federal disposal regulations. Dispose of container
and unused contents in accordance with federal, state and local requirements.

WARNING:THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO
THE STATE OF CALIFORNIA TO CAUSE BIRTH DEFECTS OR OTHER REPRODUCTIVE HARM.

Australian Hazchem Code: 3[Y]E Poison Schedule: S6
WHMIS:This MSDS has been prepared according to the hazard
criteria of the Controlled Products Regulations (CPR) and the MSDS contains
all of the information required by the CPR.

16. Other Information

NFPA Ratings: Health: 2 Flammability: 3
Reactivity: 0Label Hazard Warning:POISON! DANGER!
HARMFUL OR FATAL IF SWALLOWED. HARMFUL IF INHALED OR ABSORBED THROUGH SKIN.
VAPOR HARMFUL. FLAMMABLE LIQUID AND VAPOR. MAY AFFECT LIVER, KIDNEYS, BLOOD
SYSTEM, OR CENTRAL NERVOUS SYSTEM. CAUSES IRRITATION TO SKIN, EYES AND
RESPIRATORY TRACT. Label Precautions:Keep away from heat,
sparks and flame.Keep container closed.Use only with adequate
ventilation.Wash thoroughly after handling.Avoid breathing
vapor.Avoid contact with eyes, skin and clothing. Label First
Aid:Aspiration hazard. If swallowed, DO NOT INDUCE VOMITING. Give
large quantities of water. Never give anything by mouth to an unconscious
person. If vomiting occurs, keep head below hips to prevent aspiration into
lungs. If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. In case of contact,
immediately flush eyes or skin with plenty of water for at least 15 minutes.
Remove contaminated clothing and shoes. Wash clothing before reuse. In all
cases call a physician immediately. Product Use:Laboratory
Reagent. Revision Information:No changes.
Disclaimer:************************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in
good faith but makes no representation as to its comprehensiveness or
accuracy. This document is intended only as a guide to the appropriate
precautionary handling of the material by a properly trained person using this
product. Individuals receiving the information must exercise their independent
judgment in determining its appropriateness for a particular purpose.
MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER
EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF
MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE
INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS.
ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES
RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.************************************************************************************************
Prepared by: Strategic Services Division Phone Number: (314)
539-1600 (U.S.A.)