It's a slight elevation that I wouldn't be too concerned about. Of course, no one likes being outside of the normal reference range so I can relate to your question. If everything else is normal - liver enzymes etc - I question whether a doctor would think it was something that warranted any investigation. But, it doesn't hurt to ask about it and I might do that. At least your doctor would be on notice about it and would know that you know your direct bilirubin is elevated. I cannot see any downside to following up with your doctor. But, I really wouldn't worry too much about it at this stage.

Indirect bilirubin cannot be measured in the blood. It is determined by taking the Total bilirubin and subtracting the Direct bilirubin (both of which can be measured in the blood).

Total bilirubin is an easy way to get an idea if there might be a problem. An elevated Direct bilirubin can suggest a liver or biliary system problem. A gallstone blocking a bile duct can also result in an increased Direct bilirubin.

An elevation of Indirect bilirubin suggests a non-liver issue. It can be from Gilbert's Syndrome (which is generally thought to be a benign condition) or from hemolysis (red blood cell destruction) caused by some medications.

We know that your elevation is your Direct bilirubin so that points to the liver or biliary system - bile ducts inside and outside of the liver and the gallbladder. I would not panic about this for a second but I would probably run it by a doctor just to be extra vigilant.

The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.