For something quick and simple, just trading IWM based on the (8,55) day exponential moving average crossover works pretty well. It gives you 9.63% average annual return vs 6.58% for buy and hold. This is since 5/20/2000, which is its inception (I think - it is the earliest date for which I have data). This strategy keeps you out of IWM during the worst times, and in it for most of the good times. Not all trades are profitable (there are about 20 over around 11 years), but you do pretty well.

By trading based on the (8,55) day exponential moving average crossover, I mean buying when the 8 day crosses above the 55 day, and sell when the 8 day is below the 55 day.

For more complicated stuff, look at the timing and trading strategies on the Mechanical Investing Board. They do pretty well.

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