Guidelines not only recommended biological agents only in patients with severe psoriasis who had failed to respond to topical and systemic therapies (eg, ciclosporin and methotrexate) but also yearly monitoring of blood counts and liver function. S3guidelines on the treatment of psoriasis vulgaris (English version). Four of the five groups (i.e., Canadian, German, European, and British) used the AGREE criteria as standards in their development process. The German guidelines were published in 2007 in both complete and abbreviated versions.

Adherence To Guidelines In The Use Of Biological Agents To Treat Psoriasis In Brazil