TAC1

(redirected from Neurokinin 1)

TAC1

A gene on chromosome 7q21-q22 that encodes four different tachykinins—substance P, neurokinin A, neuropeptide K and neuropeptide gamma—which are thought to function as neurotransmitters, interacting with nerve receptors and smooth muscle cells, inducing behavioural responses and acting as vasodilators and secretagogues.

Now working their way through the developmental pipeline are two promising novel classes of drugs designed to target the physiologic mechanisms underlying this common and challenging problem: neurokinin 1 (NK1) receptor antagonists and selective opioid receptor agonists, explained Dr.

In addition, researchers are evaluating the therapeutic potential of corticotrophin-releasing factor antagonists and neurokinin 1 antagonists, which may address the relationship between stress and alcohol consumption.

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