Description

CA(PEG)n is the abbreviation for a set of compounds having polyethylene glycol (PEG) spacers with carboxy (-COOH) and amino (-NH2) termini. The unbranched, hydrophilic, discrete-length molecules have the form Carboxy-PEGn-Amine, where the subscript “n” denotes 4, 8, 12, or 24 ethylene glycol units. The carboxyl and primary amine of each compound provide specific targets for crosslinking and other conjugation methods, making these compounds useful as PEGylation reagents.

Provided as a series of 4, 8, 12 and 24 ethylene glycol units, enabling modification procedures to be optimized for a specific application while retaining all the benefits associated with protein PEGylation