Regardless of the long period of positive research on utilizing this oil against cancer, and its strong benefits and very small risk of side effects, researchers have hardly ever advanced their research into human clinical testing.

Through our discussion on the research discoveries, you will find out that the use of black seed oil in the treatments and prevention of cancer has powerful effects on many cancer types. However, the mainstream medicine still doesn't recognize this oil as incredibly beneficial.

We will talk about the possible political influence that might be disrupting clinical research with human patients with cancer, as well as the reason why drug companies like to subdue the black seed

Thousand of Years Usage of Black Seed Oil in the Cancer Treatment

Saudi Arabian researchers and Chinese researchers analyzed the scientific literature for the black seed oil usage in the treatment of cancer in two different 2011 studies. Their studies only reconfirmed the safety and the anti-cancer effects of this natural oil, and that it has been used for centuries as a traditional remedy.

Black seed oil and its extract thymoquinone have beneficial properties in the treatment of many diseases including cancer, diabetes, cardiovascular complications, kidney disease, asthma etc. It has effective and safe properties against cancer in lungs, blood system, skin, liver, cervix, kidneys, breast, and prostate.

The molecular mechanism behind this oil's anti-cancer effects are still not completely understood according to researchers. Nevertheless, the discoveries of the studies include that thymoquinone acts as an antioxidant and boosts the immune system.

Apopotosis included in this oil help in the body's elimination of the unhealthy, unneeded and old cells, as cancer cells are, without toxin releasing in the body. Moreover, the oil controls the pathway of Akt, so it has control over the process responsible for survival of cells, including both cancer and normal cells.

The anti-cancer properties of the black seed oil were recognized thousands of years ago. however, the modern scientific research showed interest in studying this traditional remedy a few decades ago.

Black Seeds and Honey Act Together

Researchers from Egypt analyzed the protective properties of Nigella grains and bee honey on the oxidative stress and the created cancer when rats were exposed to a strong carcinogen. The rats which were exposed to the carcinogen were divided into four groups.

Some of them were given black seeds or honey for food, whereas one group was given both honey and black seeds. After a period of 6 months, the rats were evaluated.

The results showed that rats which ate only black seeds were protected 80 percent against oxidative stress, while those which ate both black seeds and honey on a daily basis, got 100 percent protection against cancer formation, oxidative stress, and inflammatory reactions.

Black Seed Oil's Immense Help in Radiation Treatments

Turkish researchers noted the possibility of black seed oil being helpful to people on radiation therapy for cancer in a 2014 study. They also noted that during and after these radiation treatments, patients suffered serious negative side effects.

The researchers investigated the effects of black seed oil addition as well as the irradiation on the oxidant system in the tissues of liver in rats which were irradiated. Some of the rats were exposed to a single gamma radiation dose.

One group of rats got 1 gram of dark seed oil per kilogram of body weight 1 hour before the radiation and got a day by day measurement a while later for 10 days. Another group of rats got treatment wth radiation with a saline solution rather than dark seed oil.

The control group of rats wasn't irradiated. The investigation of the information demonstrates the dark seed oil lessens oxidative stress markers and has antioxidant properties, which likewise increases the antioxidant capacity in the rat's liver tissue.

Consequently, the utilization of dark seed oil before the treatment with radiation, and for 10 days more defended the rats from a portion of the harmful impacts of radiation.

In an Indian study in 2012, researchers examined the impact of utilizing an extract of dark seeds on mice presented to gamma radiation. The tested mice included a group of healthy mice and a group of mice with tumors. This investigation was done to imitate the human clinical setting where normal tissues of patients with cancer are presented to the hurtful impact of radiation treatment.

The mice were given dark seed extract, 100 mgs per 1 kg of body weight, before being presented to the gamma radiation. The outcomes demonstrated that the dark seed extract protected the spleen, liver, intestines and brain from the damage of gamma radiation for both the mice with tumors and the healthy ones.

Scientists' conclusion was that the fluid extract of dark seeds has defensive properties against radiation-impelled damage and biochemical changes.

They ascribed this defensive property to the capacity of the extract to rummage free radicals as well as to its antioxidant properties. So, the fluid extricated from dark seeds could be used with human patients with cancer who undergo radiation to protect against oxidative stress in ordinary tissues, and to moderate other undesirable symptoms of radiation.

This can enhance the personal satisfaction for malignancy patients. This can also improve the life-quality of patients with cancer.

Back in 2013, researchers in India used 2 groups of liver cancer rats to learn more about the use of the compound obtained from black seeds, thymoquinone. One of the groups got water with 0.01% thymoquinone as a drink, and the other just plain water. The tumor markers, liver injury markers, and liver cancer nodules, were measured in these groups after 16 weeks.

These are the following results: the group without thymoquinone intake marked significant increase in the size of the liver tumor, whereas the other group which got 20 mgs of thymoquinone per kg of body weight marked significant reduction of the tumor markers and of liver injury markers, didn't develop liver cancer nodules, and the formation of new tumor was lesser than the other group of rats.

Their conclusion was that thymoquinone is highly beneficial in the liver cancer treatment, as a result of its powerful capacity to prevent proliferation of cancer cells.

The anti-tumor effects of black seed oil and bee honey on cancer cells on human liver were evaluated by a 2012 study in Egypt. The researchers analyzed the antioxidant capacity of black seed extract and bee honey and their ability to destroy unhealthy cells like cancer cells.
What they discovered is that both black seed extract and bee honey are effective in lowering of the liver cancer cells’ viability. Moreover, both of them enhanced the antioxidant status of cells and prompted death of cancer cells by apoptosis.

Black Seed Oil Destroys Lung Cancer Cells

As reported by Saudi Arabian study in 2014, black seeds used to be part of the traditional medicine for the treatment of various diseases. Since these seeds’ anti-inflammatory, antibacterial, and antioxidant properties are well known, researchers investigated the anti-cancer properties of black seed extract and black seed oil in their usage against human lung cancer cells.
Lung cancer cells were exposed to 0.01 mg/ml to 1 mg/ml black seed extract or black seed oil for 24 hours, after which they evaluated the viability of the cancer cells.
They discovered that both black seed extract and black seed oil remarkably lowered the living cancer cells’ population as well as changed the morphology of the cells. Greater amount of the extract or oil used in the treatment of cancer cells, gave greater amount of cell death.
Moreover, both the black seed extract and black seed oil caused changing of the cancer cells typical appearance and reduction of their size. The conclusion of these researchers is that the viability of human lung cancer cells is notably reduced by both black seed oil and black seed extract.

The Components of Black Seed Destroy Malignant Brain Cancer Cells

According to the study published by Ohio State University researchers in 2013, the most aggressive type of malignant brain tumor in people with a 15 month median survival, as well as the most common one, is glioblastoma. The researchers pointed out that glioblastoma treatment required additional therapies.

The phytochemicals which occur naturally have gained much attention by the scientist since many of them reveal powerful tumor killing property. Thymoquinone, one of black seed oil’s bioactive compounds, possesses anti-inflammatory, anti-oxidant, and anti-cancer properties. Moreover, since it possesses certain cytotoxic qualities for human cells, it destroys human cancer cells without harming the healthy ones.

This particular study inspected how thymoquinone specifically represses the capacity of glioblastoma cancer cells of the brain and spinal cord from cloning themselves. However, thymoquinone doesn’t hinder the typical cell action in the spinal cord and human brain.

Another beneficial thymoquinone capacity is the restraint of autophagy genes in malignancy cells. Autophagy in malignancy cells empowers development of tumor cells by keeping up production of cellular energy.

If autophagy is repressed, then the production of cellular energy for cancer cells will likewise be repressed. The result will be regressed tumor activity, and survival expanding of organs influenced by tumors.

Along these lines, thymoquinone’s capacity to repress cancer cells from cloning themselves and its capacity to hinder cancer cells from reusing cell materials from different cells with autophagy, give an exciting cancer therapy strategy.

Black Seeds Prevent Breast Cancer

2013 Malaysian study tackled with thymoquinone’s anti-cancer proficiency when it was utilized for long haul treatment of cell lines from human breast cancer in the laboratory. Thymoquinone demonstrated a supported capacity to repress multiplication of breast cancer cella with long haul treatment. The size of the thymoquinone dose determined the length of hindrance. Greater doses gave greater restraint.

Black Seeds Destroy Leukemia Cells

In a 2013 research, scientists from Malaysia reported that there is a growing enthusiasm for usage of traditional medicine natural compounds which show potential for anti-cancer action. Nigella sativa (dark seed) is a standout amongst the most examined plants.

This yearly herb develops in nations bordering India and the Mediterranean Sea. One active compound separated from Nigella sativa is thymoquinone. The counter malignancy impact of thymoquinone, by means of the affectation of apoptosis coming from mitochondrial dysfunction, was evaluated in an acute leukemia cell line.

What scientists discovered is that leukemia cells treatment with thymoquinone stimulated apoptosis leading to death of cells. These outcomes demonstrate that thymoquinone from dark seeds can be a promising medium for leukemia treatment.

Black Seed Oil Prevents and Destroys Colon Cancer Cells

In a 2007 study, scientists from the University of Mississippi Medical Center noted that that 5-fluorouracil, the chemotherapy drug, keeps on being the chemotherapeutic highest quality level for the colon cancer treatment. But, they also noticed that there are many 5-FU negative effects because of its capacity to attack both malignant and healthy cells.

They responded to past examination discoveries demonstrating that antioxidants have a capacity to prevent certain processes of diseases, particularly cancer. The basis of their study were the most abundant catechin in green tea called epigallocatechin-3-gallate, and the most potent anti-cancer element of black seeds, thymoquinone.

Dark seeds are known for their effective scavenger capacities, preventing oxidative stress, and due to its ability to cure various diseases it has been used in the Middle East for centuries.
The aim of this study was to examine the role of continuous delivery of catechin from green tea, 5-FU, and thymoquinone from black seeds, on the metabolic action and the human colon cancer cells’ structure in the laboratory.

This study demonstrated that catechin from green tea and thymoquinone from dark seed created significant destruction of cancer cells and impeded the metabolic capacities of cells, which was comparable to cells changes in those exposed to 5-FU, chemotherapy drug.

Morphologically, cell changes happened after introduction to catechin from green tea and thymoquinone for 24 hours that was practically identical to the changes found in cells presented to the 5-FU chemotherapy drug. Eventually, the researchers agreed that a safe alternative colon cancer treatment can be provided by natural agents.

In 2004, Lebanese scientists discovered the potent role of black seed oil in the prevention and treatment of cancer.

H. pylori infection successful treatment with antimicrobial media can prompt regression of disorders associated to H. pylori. Since the resistance of H. pylori against antibiotics is expanding, it is important to discover new effective media. Black seeds has anti-helicobacter property.
This research was conducted on 88 people with non-ulcer dyspepsia in order to assess the black seeds efficiency for H. pylori eradication. The participants were divided in 4 groups which got different combinations of clarithromycin and/or antibiotics (amoxicillin), black seed oil, and anti-gastric reflex drug (omeprazole).

What the researchers discovered is that black seed oil has clinically beneficial anti H. pylori property, comparable to all the three tested drugs together.

Black Seed Oil’s Future

What a German 2011 study discovered is that thymoquinone found in the black seed oil increases the anti-cancer properties of the drug doxorubicin, on which chemotherapy is based and which has cardiotoxicity ability, in specific cell lines.

Researches from Singapore noted that due to the developed resistance of cancer cells on the therapeutic agents for cancer, new agents for breast cancer treatment must be discovered. In a research with mice, thymoquinone has proven to suppress the growth of tumor, and its effect was increased by combining it with doxorubicin.

Clinical trials with Human Patients with Cancer

Wayne State University in Michigan researchers discovered that further studies on black seeds are warranted.

Oman research gives his opinion about the direction of future black seed oil researches. The thymoquinone use in animal researches with cancer forms as well as in test tube research with human cells of cancer have been completely investigated. Since there is enough generated information about thymoquinone from researches, they should move to clinical experiments.

Conclusion

We are wondering why black seed oil and thymoquinone are still researched in laboratories instead of involving trials with people, as more 120 researches point to their significant anti-cancer effect.
Black seeds and black seed oil have been used for dozens of diseases with great success ever since that time throughout a large portion of the world.

Ever since the ancient time, black seed was used throughout the world as a traditional remedy for the treatment of various diseases. Black seed oil was found in Egyptian Pharaoh Tutankhamen’s tomb. Moreover, archeologists found a combination of black seeds, bee’s wax, and honey in a pilgrim bottle dating from the Old Hittite Period in 1650 BC, in Turkey.

Although black seeds and the oil from them are food at first place, they are still investigated in laboratory concerning their anti-cancer property, as if they are some harmful toxic ingredients. They are used as daily tonics, flavoring food, and traditional medicine for thousands of years. There’s no more need of animal studies or test tubes to prove their effectiveness and safety. Instead we need clinical trials.

Why Is Black Seed Oil’s Clinical Research in the Treatment for Cancer So Rare?

The answer to this question is probably the power of pharmaceutical industry. We saw that many researches have proven the beneficial effects of black seed oil and thymoquinone in the cancer treatment, wither alone, or in combination with other chemotherapy drugs.

The fact that a natural seed extract can be more potent than drugs used in chemotherapy is surely great for cancer patients, but certainly bad for pharmaceutical companies which care only about their profit.