Abstract:This work presents a closed-form, numerically derived model of a key microfluidic electrokinetic separation system component, the cross injector. The model fits into a framework such that it can be combined with a network of other component models, such as a mixer, reactor, separation channel, and detector, to model a complete microfluidic separation system. The model is based on a reduction of the full 5-dimensional parameter space to a manageable 2-dimensional parameter space. The resultant model is valid for Peclet numbers ranging from 10 to 5000 and shows a worst case variance equal to the channel width squared.