Application Notes: The cross-reactivity of this scFV with a panel of heterologous infectious bronchitis virus strains has been confirmed in ELISA experiments (Fernandes et al, 2010). In Western blot analysis, this scFv has been shown to bind IBV nucleoprotein (Fernandes et al, 2010). This scFv could be employed in immunodiagnostic techniques.

Antibody first published in:
Fernandes et al. Construction of an avian single chain monoclonal antibodies (scFv) library by phage display that cross-reacted with heterologous avian infectious bronchitis virus strains Cienc. Rural vol.40 no.6 Santa Maria June 2010 PMID:Note on publication:
Describes the original generation of this scFv by phage display, and characterisation of its specificity by ELISA and Western blotting.