Tagged: Herb

I am a scientist. But I also work in Berkeley, CA. And it was only a matter of time before these worlds collided…

Let’s talk about the science behind a very popular pregnancy herbal supplement – Raspberry Leaf Tea.

(My prenatal yoga instructor is not going to be happy with me.)

Though I proudly bought my Prenatal Vitamins, Ovulation tests, and pregnancy pee sticks, I hid my “Mother to Be” tea underneath a red pepper on the supermarket conveyor belt the other day. Yes, I bought the tea but I am still conflicted about buying into the concept that a tea can magically (uh, I mean biologically) strengthen a uterus.

In addition to the gushing words from my yoga instructor, the internet offers up unlimited gems about the stuff. These words of wisdom range from the very appealing – “It strengthens the uterus and pelvic muscles which leads to shorter and easier labors” to the anecdotal – “…my sister’s sister took it at 35 weeks and had her baby within 48 hours” to the very confident “Has been shown to concentrate the effects of contractions to make them more effective”

Alright then, challenge accepted! Time to dig up some scientific evidence for these claims.

So, can raspberry leaf tea do all these amazing things the internet claims it can: strengthen the uterus, shorten labor, decrease assisted delivery, and so on?

Well, despite this supplement being a fan favorite over in the midwife community (63% of American midwives recommend this supplement to stimulate labor [1]), overall it seems like the jury is still out as to its pro’s and con’s.

A very comprehensive scientific literature search by Holst et al. in 2009 [2] found only six studies testing the effects of the tea in a lab, with non-human or petri dish subjects, and only five studies that took place in the clinic. I do want to note that the small number of studies unveiled was not for lack of trying – these authors including an obscure paper from 1941 that only included three women! Anyway, the lab studies were mixed. Overall, raspberry leaf tea was shown to facilitate more rhythmic contractions in uterine tissue but also showed conflicted toning and relaxing effects.The five clinical studies did not reveal any strong effects of the elixir (positive or negative) in humans. Some studies did show a shorter first or second stage of labor but the tea only knocked off a few minutes (wow!) and one study showed shorter gestation length… but only by a couple of days (insert more sarcastic enthusiasm).

After Holst and colleagues published their efforts combing the literature, another lab study [3] was conducted to directly test uterine contractions in the presence of raspberry leaf tea in vitro (outside the body). When applied directly to uterine tissue from non-pregnant rats, raspberry leaf tea had no effect on uterine contractibility. However, when the researchers stuck a pregnant rat’s uterus in a petri dish with some the tea – BAM! – the cellular response rivaled that of Oxytocin. Oxytocin, among the many wonderful things it can do during birth, is the main hormone in charge of making sure the uterus steps up and does its job to help get baby out into the world. The researchers then tested whether raspberry leaf tea played Oxytocin’s little helper in this process. With only six test subjects, however, they found results split in two directions: half of the test subjects showed that oxytocin-induced contractions were augmented with raspberry leaf tea, but the other half showed the same augmentation followed by inhibition of contractions. Hmmmm. At the end of the day, though, the authors did not even want to put weight into their own findings (which I actually found quite promising so I was a bit bummed). They concluded that since humans are unlikely to get the same dose that they used on their rat uteri, this effect is probably not translatable to the intact, in vivo uterus of your average pregnant women.

Now for the potential adverse effects. Well, fortunately, there were mostly no adverse effects noted. However, there was one study that found odd trans-generational effects [4]. That’s right, drinking raspberry leaf tea while pregnant may affect your baby and your baby’s baby. In this study, mother rats were fed raspberry leaf extract every day from conception to weaning. The babies of these mother rats showed signs of early puberty and the babies’ babies showed greater growth restriction. Important to point out, though, these rats were consuming raspberry leaf extract throughout the entire pregnancy. I cannot put a percentage on the number of female humans consuming the tea throughout pregnancy but I am guessing more women are taking it primarily when they start to hit that “holy crap, I have to push out a screaming child!” stage. My unscientific analysis of pregnant friends puts this stage somewhere between the second and third trimester but rarely during the first, when the developing womb baby is most likely to be affected by what we are putting into our bodies and when these effects may affect the womb baby’s egg babies. Of course, more studies are needed before we can conclude that this is or is not a scary potential result of raspberry leaf consumption.

As for those benefits –

Sorry, internet, but I have to side with the scientist buzzkills, Holst and colleagues, when they state – “The fact that the product has been in traditional use for decades does not constitute evidence”. There simply are not enough studies to back up the claims that raspberry leaf tea is a pregnancy super juice.

With that said, in honor of full disclosure, I must admit that I have a steaming pot of “Mother to Be Tea” sitting next to me as I write this.

Yup, there will always be a tiny part of me swayed by the fact that it worked for somebody’s sister’s sister.