Arterial spin labelling (ASL) is the primary
non-invasive MRI approach to measure cerebral blood flow in healthy subjects
and patients. Recently,
a consensus paper has recommended segmented versions of 3D spin-echo readouts
like GRASE, but these are susceptible to motion and have poor temporal
resolution. To alleviate these drawbacks, we propose to accelerate the 3D GRASE
readout and utilize 2D CAIPIRINHA for the reconstruction. We demonstrate that
our approach is superior or at least equivalent to the 2D GRAPPA technique, depending
on the acceleration factor used. The proposed approach will particularly benefit
functional and clinical ASL applications.

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