Participating Institutions

This partnership represents a unique blending of academic, institutional, and industrial efforts with a history of producing technological advances and innovations, expertise in infectious diseases and drug development, and proven ability to work with challenging protein targets, employing state-of-the-art structural genomic research.

Click on the logos below for more information about each site.

SCRI is responsible for the overall management for the SSGCID structure determination effort as well as protein purifications from bacterial expression and mammalian systems as well as cloning, expression and purification of protein-protein complexes.

WSU provides equipment and expertise for NMR-based determination of the structures of a small number of proteins that cannot be solved by X-ray crystallography.

The UW PPG provides high-throughput cloning and testing of target proteins in bacterial expression vectors, as well as large-scale protein production and purification. The UW NMR provides equipment and expertise for NMR-based determinatnion of the structures of a small number of proteins that cannot be solved by X-ray crystallography.

UDB's role in the SSGCID included gene construction and expression testing, large-scale protein production and purification; crystallization screening and production, pre-screening of crystals before they are sent for data collection at the synchrotron beam-lines, and structure determination using the resulting data.