The intersection of Highways 3 and 35 has traffic volumes of 11,200 vehicles per day and is the location of the largest 7-Eleven in Canada (by floor space) and the 16-foot roadside statue of "The World's Largest Honey Bee" (the Giant Bee in Falher, Alberta, is actually bigger at 22 feet 8 inches).

The post office of Tisdale, provisional District of Saskatchewan, North West Territories was created on February 1, 1904. The community was originally known as "Doghide" after the Doghide River that flows through the town, but with the arrival of the railway the community was renamed "Tisdale" in honour of F.W. Tisdale, an employee of the Canadian Northern Railway.[3]

Western Canada’s biggest gun shoot out took place just east of Tisdale in 1920. The historic gunfight involved a posse of Saskatchewan Provincial Police and four outlaws[3]

In 2005, Tisdale celebrated its 100th birthday with a homecoming celebration in conjunction with Saskatchewan's centennial. The town also underwent beautification projects, including the construction of a new town square.

For 60 years, until October 2015,[7] Tisdale was known as the "Land of Rape and Honey" due to its significance in both rapeseed and honey production. Tisdale is also known as the Honey Capital of Saskatchewan. One third of the farmland in the Northeast region is cropped into canola and 10% of the honey produced in Canada comes from this area. Traditionally the area produces about 9 million pounds ($7.2 million) in honey. Due to the obvious alternate meaning, industrial metal band Ministry named their 1988 album The Land of Rape and Honey after seeing the motto on a Tisdale souvenir mug.[8] The town adopted the new motto "Opportunity Grows Here" on August 22, 2016.[9]

The world's second largest (only to that of Falher, Alberta's) honey bee statue (7 feet (2.1 metres) in height, sixteen feet long, four feet wide, and weighing two tonnes) is located as a roadside attraction in Tisdale.[10][11]

Tisdale is the regional sports hub which boasts a 6 sheet curling rink, indoor and outdoor skating rinks, soccer and football fields, indoor gun range and one of Saskatchewan's most picturesque 9 hole golf courses situated along the Doghide River. Tisdale's sporting facilities draw teams and individuals from all over Northeast Saskatchewan and beyond.