Abstract

The increase/modification of the Cisplatinum therapeutic index by neoplastic tissue exposure to optical radiation emitted between 400–2000 nm was studied; Cisplatinumum molecules do not absorb between 400 nm–2 □m. Doppler ultrasonography indicates that, following exposure, the living tissue local micro‐vascularisation increases in a controlled and reversible way. The increase in the Cisplatinum therapeutic index may be produced by accelerating the intracellular hydrolyze processes due to the water molecules absorption in the near infrared. The irradiation makes possible the use of Cisplatinumum doses 10 times lower than in conventional chemotherapy; this generates lower secondary effects (kidney toxicity) while increasing the drug antineoplastic effect.