Large bowel obstruction

Presentation

Young lady presented with symptoms of acute abdominal pain since 3 days. Outside evaluation revealed doubtful renal calculi and was given symptomatic treatment. Since pain was not subsiding, she was referred to a higher centre. Bilious vomiting was observed at the time of sonographic study of abdomen.

Case Discussion

Microscopic Description:Section shows fragments of large intestinal
mucosa containing part of an ulcerating neoplasm with villous architecture in
places lined by cells displaying nuclear crowding, stratification and
hyperchromasia, variably conspicious nucleoli and frequent mitosis.
Disorganised glands with luminal necrosis and moderate to severe degree of
cytological atypia and apical mitosis are present in the lamina propria and
also between muscularis mucosal fibres. There is associated inflammation and
desmoplasia