The functions of the VPO are stated in the Government Instrument made under Article 55 of February, 2008. From the above, therefore the major roles and functions of this Office are to assist the President on all matters concerning the United Republic of Tanzania, and in particular:

Coordinate Union Affairs;

Coordinate linkages between the Government of the United Republic of Tanzania and Government of Zanzibar for Non-Union Affairs;

Formulate Environmental Policy and ensure its implementation;

Monitor and coordinate National Environmental Management Council (NEMC) activities;

Oversee implementation of various socio-economic projects; and

Ensure continuous performance improvement and development of human resources under the Office.