A new study by researchers at Rice University in Houston used computer simulations to explore the beginnings of the molecular process that marks the start of Alzheimer’s disease, which is triggered by the aggregation of a common protein called amyloid beta. The Rice investigators are the first to model the energy landscape of the pathogenic protein's assembly of many copies into its toxic form.

The team of investigators at Rice University who built computer simulations of amyloid beta proteins. From left, Weihua Zheng, Min-Yeh Tsai, Peter Wolynes and Mingchen Chen. Photo credit: Jeff Fitlow/Rice University

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