Unlike surgical interventions that require stitches and injections, PrePex involves the simple application of a local anaesthetic cream, and the procedure is up to five times faster than surgery. The device is worn for seven days, during which it slowly stops blood circulation to the distal foreskin to dry it out in preparation for bloodless circumcision. The product can be worn under clothes and does not disrupt the wearer's daily activities.

"Most surgical procedures require a sterile environment, which is often not available in rural or low-resource settings; PrePex only requires a clean environment," said Frost & Sullivan Best Practices Research Analyst Caeri Dunnell. "A primary care nurse can fit the PrePex device, reducing the burden on doctors or highly-skilled surgical nurses. This non-surgical approach allows governments to take their VMMC campaigns to wider geographic areas."