AIM AND OBJECTIVES: Edentulism is an incapacitating and irretrievable condition which can lead unswervingly to functional limitation, physical, psychological and social handicap. Maintenance of bone after tooth loss to improve retention, function, and performance of the restoration is a challenging task. The existence of a thin edentulous ridge signifies a clinical situation that is more complex for the placement of endosseous implants. Dental rehabilitation of the edentulous ridges with oral implants has become a routine treatment modality in the last few decades with consistent long term results...

Bioactive macromolecular peptides and oligonucleotides have significant therapeutic potential. However, due to their size, they have no ability to enter the cytoplasm of cells. Peptide/Protein transduction domains (PTDs), also called cell-penetrating peptides (CPPs), can promote uptake of macromolecules via endocytosis. However, overcoming the rate-limiting step of endosomal escape into the cytoplasm remains a major challenge. Hydrophobic amino acid R groups are known to play a vital role in viral escape from endosomes...

OBJECTIVES: Humeral head sacrificing procedures are more favored in elderly patients with complex proximal humerus fractures because of high incidence of failures and complications with osteosynthesis. The purpose of this study is to assess the outcome of second generation locked plating techniques in 3 and 4 part fractures in active elderly patients >70years with an emphasis on function and complications. MATERIALS AND METHODS: 29 patients with displaced 3 and 4 part proximal humerus fractures were treated using the principles of second-generation proximal humerus locked plating...

Identification and quantification of pathogen threats need to be a priority for the Canadian swine industry so that resources can be focused where they will be most effective. Here we create a tool based on a Bayesian Belief Network (BBN) to model the interaction between biosecurity practices and the probability of occurrence of four different diseases on Canadian swine farms. The benefits of using this novel approach, in comparison to other methods, is that it enables us to explore both the complex interaction and the relative importance of biosecurity practices on the probability of disease occurrence...

BACKGROUND: Children with Reactive Attachment Disorder (RAD) have serious socio-behavioral problems and often rely on socially abnormal, aggressive, and manipulative forms of communication. Little is known, however, about the influence of teachers on the socio-behavioral development of children with symptoms of RAD. AIMS: This longitudinal study examined the influence of teacher sensitivity on the socio-behavioral development of children with symptoms of RAD across one school year...

This intervention study examined teachers' use of verbal praise and reprimands as specific components of teacher behavior management that can promote children's development in schools. The impact of teacher praise and reprimands on children's development was examined in the context of a teacher-mediated, classroom intervention. The sample involved 570 children and 30 teachers from second grade classrooms in 15 primary schools. The Good Behavior Game was implemented in half of the classrooms based on random assignment within schools...

INTRODUCTION: There is no recommendation concerning wisdom teeth (WT) extraction in mandibular orthognathic surgery. We carried out an investigation among the members of the French Society of Stomatology and Oro-maxillofacial Surgery (SFSCMFCO), in order to evaluate the practices and habits of maxillofacial surgeons in this field. MATERIALS AND METHODS: We emailed the 424 members of the SFSCMFCO with a questionnaire. RESULTS: We obtained 143 feedbacks that could be exploited...

Previous studies found different trajectories of conflicted relationships with teachers predictive of academic underachievement. However, little is known about what places children at risk for atypical conflict trajectories. This follow-up study examines whether African American ethnicity, IQ, and SES are unique predictors of teacher-student conflict trajectories taking into account sociobehavioral predictors, including aggression and prosocial behavior. The study included the same ethnically diverse sample of 657 academically at-risk children in which previously four latent growth classes of conflict trajectories (grades 1-5) predictive of underachievement were identified...

This study was conducted to 1206 women who had cervical cancer screening at Chonburi Cancer Hospital. The spilt-sample study aimed to compare the efficacy of abnormal cervical cells detection between liquid-based cytology (LBC) and conventional cytology (CC). The collection of cervical cells was performed by broom and directly smeared on a glass slide for CC then the rest of specimen was prepared for LBC. All slides were evaluated and classified by The Bethesda System. The results of the two cytological tests were compared to the gold standard...

This study was conducted to evaluate effects of rhBMP-2 applied at different concentrations to sandblasted and acid etched (SLA) implants on osseointegration and bone regeneration in a bone defect of beagle dogs as pilot study using split-mouth design. Methods. For experimental groups, SLA implants were coated with different concentrations of rhBMP-2 (0.1, 0.5, and 1 mg/mL). After assessment of surface characteristics and rhBMP-2 releasing profile, the experimental groups and untreated control groups (n = 6 in each group, two animals in each group) were placed in split-mouth designed animal models with buccal open defect...

OBJECTIVES: Spinal meningiomas are benign and relatively rare tumors. These tumors present about only 25% of primary spinal tumors. Although spinal meningiomas are considered as slowly growing benign tumors, yet they may cause devastating neurological deficits rendering patients crippled. This study describes performing a posterolateral approach to surgically treat anterior based cervical meningioma. We hereby report on 16 cases operated upon using this approach, and we present our results and display some of our cases with special emphasis on achieving total resection, rate of recurrence and the neurological outcome...

We report a case of bilateral chylothorax without evidence of chylous fistula in a 62-year-old man following total laryngectomy and bilateral selective neck dissection for laryngeal cancer. Chylous fistulae, a well-known complication of neck dissection, occurs following 1% to 2% of these surgeries. On rare occasions, the chyle leak may communicate with the pleural space, resulting in chylothorax. This is a rare but potentially life-threatening complication. Bilateral chylothorax following neck dissection is even rarer, with less than 25 cases reported in the literature...

This study presents a model to assess the oil spill risk in Garorim Bay in Korea, where large-scale oil spill accidents frequently occur. The oil spill risk assessment is carried out by using two factors: 1) The impact probability of the oil spill, and 2) the first impact time of the oil that has been spilt. The risk assessment is conducted for environmentally sensitive areas, such as the coastline and aquaculture farms in the Garorim Bay area. Finally, Garorim Bay is divided into six subareas, and the risks of each subarea are compared with one another to identify the subarea that is most vulnerable to an oil spill accident...

A non invasive sampling and remediation strategy was developed and implemented at shoreline contaminated with spilt diesel. To treat the contamination, in a practical, cost-effective, and safe manner (to personnel working on the stockpiles and their ship loading activity), a non-invasive sampling and remediation strategy was designed and implemented since the location and nature of the impacted geology (rock fill) and sediment, precluded conventional ex-situ and any in-situ treatment where drilling is required...

The applications of total variation (TV) algorithms for electrical impedance tomography (EIT) have been investigated. The use of the TV regularisation technique helps to preserve discontinuities in reconstruction, such as the boundaries of perturbations and sharp changes in conductivity, which are unintentionally smoothed by traditional l2 norm regularisation. However, the non-differentiability of TV regularisation has led to the use of different algorithms. Recent advances in TV algorithms such as the primal dual interior point method (PDIPM), the linearised alternating direction method of multipliers (LADMM) and the spilt Bregman (SB) method have all been demonstrated successful EIT applications, but no direct comparison of the techniques has been made...

In this study, we used spilt luciferase complementation assay strategy in order to further elucidate the main role of WD-40 repeats of Apaf-1 molecules in apoptosome formation. In the presence of ATP and cytochrome c, Apaf-1 monomers oligomerize and provide a platform for the activation of procaspase-9 and subsequently procaspase-3/7. For a detailed biochemical and structural investigation of Apaf-1 function and apoptosome formation, several studies have been made in recent years. However, many questions related to in vivo evaluation of this phenomenon have been persisting to answer...

This paper compares the effects of exposure to exogenous melatonin (MEL), short days (SD, 8h of light) and long days (LD, 16 h of light), on reproductive activity, sperm motility and other reproductive variables, in Blanca Andaluza bucks. Fourteen males were spilt into two groups of seven animals (G1 and G2). They were subjected to five alternations of 2 months of LD followed by 2 months of SD or MEL before the experimental period of three consecutive intervals of: (1) 2 months of SD (G1, N=7) or MEL (G2, N=7); (2) 2 months of LD (G1+G2, N=14); and (3) 2 months of SD (G2, N=7) or MEL (G1, N=7)...

Little is known about the recovery trajectory from small to moderate spills (<1000 t), particularly in the sub-tropics. On 11 March 2009 the MV Pacific Adventurer spilt 270 t of bunker fuel oil 13 km off Moreton Island, Australia, impacting wetlands, sandy beaches and rocky shores. This study examines the recovery of the rocky shore community four years after the spill. Results indicate that recovery on Moreton Island is taking longer than the 3-4 years suggested by the literature. The upper shore is recovering faster than the mid shore and is nearly recovered while the mid shore is still in the recovery process...

BACKGROUND: Inflammatory periodontal diseases are initiated by microbial biofilms. The reduction of the biofilm is important in the management of the disease. This study compares periodontopathogen levels following the treatment of chronic periodontitis using Er:YAG laser debridement and mechanical scaling and root planing. METHODS: Using a spilt-mouth design, two quadrants were randomly allocated for treatment. Two hundred and fifty two subgingival plaque samples were collected from 21 patients, before treatment (baseline) and at 6- and 12-wk post therapy...

This longitudinal study examined developmental links between closeness in teacher-child relationships and children's receptive language ability from the end of the preschool years into the early elementary years, while controlling for changes in peer interaction quality and child behavioral functioning. The sample included children and their parents and teachers (N = 4,983) participating in the Longitudinal Study of Australian Children (LSAC) at ages 4-5, 6-7, and 8-9 years (3 waves). Teachers reported on levels of closeness in relationships with individual children...