Reso at 1600x1200. As Ben noted, this does not happen with any browser under WindowsXP. however, i use Linux and Mac which shows the same problem with Firefox. i'll test with opera to see if the problem persist. Do you have ads on the side column?

But it's only the newsletter box that overlaps with the main content, right? Nothing else?

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I don't know is you've adjusted anything since you last posted, but yes, it's only the newsletter box that overlap. This is only inherent in Linux and Mac with FireFox 2 and Opera. No problem with Windows.