Coagulation Testing

Following on from its successful
validation in blood glucose testing, Universal Biosensors (UBI) has adapted its
electrochemical cell to measure Prothrombin Time (PT/INR), a test used to
monitor the effect of the anticoagulant therapy warfarin.

UBI has
developed the Xprecia Stride™ Coagulation Analyzer for Siemens Healthcare
Diagnostics, to provide a quick, convenient and accurate method for medical
practitioners to conduct the test.

The test is used to maintain
patients on a safe and effective dose of warfarin. If patients are taking too
much warfarin they are at risk of serious bleeding events and if too little
they are at risk of thrombosis. The prothrombin time test allows physicians to
adjust patient doses for diet and lifestyle changes. It is estimated that over
10 million people are taking warfarin and more than 200 million PT-INR tests
are conducted each year worldwide.

The point-of-care coagulation
monitoring market is estimated to be worth approximately US$1 billion globally
with point-of-care PT-INR testing making up over 65% of this market.

UBI has signed a
long term supply and manufacturing agreement with Siemens to exclusively
manufacture three test strips for the point-of-care coagulation market.
The first product, a PT/INR test, was launched in December 2014. Siemens will
register, market and sell these point-of-care coagulation tests globally.

Point-of-care coagulation testing
takes place in three broad settings:

The coagulation testing products
being developed and manufactured for Siemens will be targeted at the first two
market segments above,

In addition, UBI is developing its own system for use in decentralised settings including the patient self-test market.
Incorporating specific features that are suited to these setting, UBI aims to distribute this system via specialist distributors in key
international markets.