Defending champion and fifth-seeded Marin Cilic of Croatia saved a match point and swept the last five games to down Spanish qualifier Feliciano Lopez 4-6, 7-6 (5) 7-5.

Also winning were second-seeded Tomas Berdych of the Czech Republic, No. 3 Juan Martin del Potro of Argentina and No. 4 Jo-Wilfried Tsonga of France. But the No. 6 Sam Querrey, the 2010 champion, was ousted by former four-time tournament winner Lleyton Hewitt, who won 5-7, 6-3, 6-4.

Murray resumed his match against Mahut at 2-2 in the second set and fought off three break points in his first two service games before beating the Frenchman in the tiebreaker.

The top-seeded Scot then took charge early against Matosevic, breaking the Australian to lead 2-1 and again in the fifth game. A break for 1-0 gave Murray a perfect start to the second set and a further break for 4-1 all but sealed his opponent’s fate.

"The hardest part is just the waiting around," Murray said. "We came off maybe three times yesterday. Today, the same thing again, a lot of waiting around for my match this afternoon. It’s important to make sure you sort of relax and don’t waste too much energy between matches."

American Denis Kudla reached his first ATP Tour quarterfinal with a 6-1, 6-3 win over Kenny De Schepper of France, and Benjamin Becker of Germany upset seventh-seeded Alexandr Dolgopolov of Ukraine 7-6 (5), 7-5.