ABSTRACT:Standardization was carried out on the basis of detailed organoleptic and microscopical evaluation of the plant which includes morphology and microscopy as well as WHO recommended physicochemical studies. The results of the standardization may throw immense light on the botanical identity of the plant Santolina chamaecyparissus which may furnish a basis of judging the authenticity of the plant and also to differentiate the drug from its allied species and detect adulterants.