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This study was supported by grants from the Finnish Pediatric Research Foundation, the Sigrid Juselius Foundation and the Helsinki University Central Hospital research funds.

The authors have nothing to disclose.

The authors received no writing assistance.

Study concept and design: MPP; acquisition of data: AM; analysis and interpretation of data: AM, MPP; drafting of the manuscript: AM, MPP; critical revision of the manuscript for important intellectual content: JL, HJ; statistical analysis: AM; obtained funding: MPP; administrative, technical, or material support: HJ; study supervision: MPP. All authors have agreed on the content of the manuscript. The authors have no conflicts of interest.

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