Bladder Exstrophy-Epispadias-Cloacal Exstrophy Complex

National Organization for Rare Disorders, Inc.

ImportantIt is possible that the main title of the report Bladder Exstrophy-Epispadias-Cloacal Exstrophy Complex is not the name you expected.

Disorder Subdivisions

None

General Discussion

Bladder exstrophy-epispadias-cloacal exstrophy complex is a spectrum of anomalies involving the urinary tract, genital tract, musculoskeletal system and sometimes the intestinal tract. In classic bladder exstrophy, most anomalies are related to defects of the abdominal wall, bladder, genitalia, pelvic bones, rectum and anus.

Bladder exstrophy is a rare developmental abnormality that is present at birth (congenital) in which the bladder and related structures are turned inside out. The rear portion of the bladder wall (posterior vesical wall) turns outward (exstrophy) through an opening in the abdominal wall and urine is excreted through this opening. The extent of the exstrophy depends on how large the opening is. The mildest form is when there is a defect or opening in the tube that carries urine out of the body from the bladder (urethra) and is termed epispadias.

The most severe form is when there is a defect in the urethra, bladder and bowel (cloacal exstrophy). Classic bladder exstrophy is when there is a defect in the urethra and bladder and is intermediate in severity. The underlying cause of this complex is not known. The physical characteristics are the result of a developmental abnormality during embryonic growth in which the cloacal membrane is not replaced by tissue that will form the abdominal muscles.

Supporting Organizations

Association For Bladder Exstrophy Community

6737 West Washington Street

Suite 6737

West Allis, WI 53214

USA

Tel: (414)918-9002

Tel: (866)300-2222

Email: admin@bladderexstrophy.com

Website: http://www.bladderexstrophy.com

Birth Defect Research for Children, Inc.

976 Lake Baldwin Lane

Orlando, FL 32814

USA

Tel: (407)895-0802

Email: staff@birthdefects.org

Website: http://www.birthdefects.org

Genetic and Rare Diseases (GARD) Information Center

PO Box 8126

Gaithersburg, MD 20898-8126

Tel: (301)251-4925

Fax: (301)251-4911

Tel: (888)205-2311

Website: http://rarediseases.info.nih.gov/GARD/

NIH/National Kidney and Urologic Diseases Information Clearinghouse

3 Information Way

Bethesda, MD 20892-3580

Fax: (703)738-4929

Tel: (800)891-5390

Email: nkudic@info.niddk.nih.gov

Website: http://www.kidney.niddk.nih.gov/

National Association for Continence

P.O. Box 1019

Charleston, SC 29402-1019

United States

Tel: (843)377-0900

Fax: (342)377-0905

Tel: (800)252-3337

Email: memberservices@nafc.org

Website: http://www.nafc.org

Pull-Thru Network

1705 Wintergreen Parkway

Normal, IL 61761

USA

Tel: (309)262-2930

Email: PullthruNetwork@gmail.com

Website: http://www.PullthruNetwork.org

Ureterosigmoidostomy Association

P.O. Box 392

Brunswick, ME 4011

USA

Tel: (207)725-2753

Email: kascar@yahoo.com

Website: http://www.ureterosigmoidostomy.com/

Urology Care Foundation

1000 Corporate Blvd

Linthicum, MD 21090

USA

Tel: (410)689-3700

Fax: (410)689-3896

Tel: (800)828-7866

Email: Info@UrologyCareFoundation.org

Website: http://www.urologyhealth.org/

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). For a full-text version of this report, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

Last Updated: 8/17/2007Copyright 2007 National Organization for Rare Disorders, Inc.

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