Paracetamol (acetaminophen in the United States) appears to have more cardiovascular, gastrointestinal (GI), and renal toxicity, as well as increased risk of mortality, than has been previously assumed, especially at high doses, according to a systematic review of the literature published online.

Exposure to biologics around the time of conception does not appear to have negative effects on neonates, according to data from the German biologics RABBIT (Rheumatoid Arthritis Observation of Biologic Therapy) registry.

Although patients with rheumatoid arthritis (RA) undergo radiological evaluations, the actual use of radiological imaging in RA has not been adequately reported. A population-based study evaluated the use of radiological procedures in patients with RA compared with patients without RA.

Hydroxychloroquine should not be routinely given to patients with mild to moderate pain associated with osteoarthritis (OA) of the hand, according to the results of a randomized, double-blind, placebo-controlled, multicenter study.

Two conditions characterized by inflammation are linked, according to researchers: periodontal disease and rheumatoid arthritis (RA). In fact, it is possible that periodontal disease may trigger the onset of RA.

Higher body mass index (BMI) in patients with rheumatoid arthritis (RA) is linked to a poorer response to a second-line biologic drug after failure of first-line treatment with a tumor necrosis factor-alpha (TNF-alpha) inhibitor, according to a study published online in Joint Bone Spine.