Phase I Study of Heme Arginate With or Without Tin Mesoporphyrin in Patients With Acute Attacks of Porphyria

This study has been completed.

Sponsor:

National Center for Research Resources (NCRR)

ClinicalTrials.gov Identifier:

NCT00004398

First Posted: October 19, 1999

Last Update Posted: December 9, 2005

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PROTOCOL OUTLINE: This is an randomized, unblinded, multicenter study. Patients are randomized to receive heme arginate alone or both heme arginate and tin mesoporphyrin.

Patients receive a single intravenous dose of tin mesoporphyrin immediately before the first dose of heme arginate. Heme arginate is administered daily for 4 days.

Patients are followed at 3 and 6 days after treatment.

Eligibility

Information from the National Library of Medicine

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