A step change in operational performance is needed

Ashley Woodcock, head of School of Translational Medicine, University of Manchester,

Helen P Critchley, senior clinical research associate

1JP Moulton Charitable Foundation, Sevenoaks, Kent TN14 7SD, UK

hpcritchley{at}yahoo.com

The JP Moulton Charitable Foundation began funding non-commercial clinical trials in April 2004. Applications had to demonstrate good scientific rationale, expertise in the area of research, clear budget breakdowns, and achievable targets. If funding was approved, the foundation requested a detailed breakdown of costs, milestones for payment against recruitment, detailed quarterly progress reports, and …