Abstract:

A method of selection of DNA aptamers to breast tumor tissue based on the use of potoperative material has been developed. Breast cancer tissue were used as the positive target; the negative targets included benign tumor tissue, adjacent healthy tissue, breast tissues from mastopathy patients, and also tissue of other types of malignant tumors/ Tese DNA aptamers can be used for identification of protein markars, breast cancer diagnostics, and targeted delivery of anticancer drugs.

The development of an aptamer-based electrochemical sensor for lung cancer detection is presented in the work.A highly specific DNA-aptamer, LC-18, selected to postoperative lung cancer tissues was immobilized onto a gold ...

Here we descrabe a method of forming large arrays of free magnetic Ni-nanodiscs 50 nm thick coated on both sides with layers of 5 nm thick Au. The antitumor effect of the magnetic nickel gold-cjated nanodiscs and DNA aptamer ...

A molecular biosensor based on DNA aptamers (aptasensors) for the diagnosis of lung cancer in blood plasma samples was designed. To create the aptasensor, aptamer 17_80, obtained in the study of postoperative material, was ...

Biomedical applications of magnetic nanoparticles in a magnetic field have exceeded many expectations in cancer therapy. Magnetic nanoparticles are effective heat mediators, drug nanocarriers, and contrast agents; various ...