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Size of hippocampus associated with PTSD therapy benefits

Size of that key memory region, the hippocampus, appears to be not simply a risk factor for PTSD, but also key to whether sufferers will respond positively to exposure therapy.

Following previous research showing that having a smaller hippocampus is associated with increased risk of PTSD, a study involving 40 participants with PTSD and 36 trauma-exposed healthy controls has found that those PTSD patients who responded to the treatment had larger hippocampi compared to those who didn’t benefit from the therapy.

The participants were evaluated at baseline and after 10 weeks, during which time the PTSD group had prolonged exposure therapy.

The study found that both the resilient controls and the 23 patients with PTSD who responded to treatment had greater hippocampal volume at the beginning of the study than the 17 non-responders.

The findings add to growing evidence that the hippocampus is key to distinguishing between cues that signal safety and those that signal threat.

Given all the research showing the importance of sleep for consolidating memories, it should come as no great surprise that the reverse is also true: depriving yourself of sleep could help you forget experiences you would prefer not to remember.

Following a study showing that playing Tetris after traumatic events could reduce memory flashbacks in healthy volunteers, two experiments have found playing Tetris after viewing traumatic images significantly reduced flashbacks while playing Pub Quiz Machine 2008 (a word-based quiz game) increa

A study in which nearly 50 participants consumed either alcohol (.4 or .8 g/kg, around 2 or 4 glasses of wine) or a placebo drink, performed a memory task, then were shown a video of serious road traffic accidents, has found that those given the smaller amount of alcohol experienced more flashba