The lessons science and pharmacology teach us about
achieving optimal health, vitality and maximal lifespan with a low net carb, high saturated fat, evolutionarily paleolithic-styled diet aligned with my ancestral heritage and how I lost 50 pounds of body fat. A sorta fairy story.

Many factors affect what goes on in our small intestines and colon. The gut environment is regulated by pH, transit time, organic acids and various gases emitted by our little zoo. With over 1000 species in there, each has to be fed and each cross-feeds each other as well as us, the host. Populations shift quickly like based on the dynamics in there. Our colonocytes devour much of the butyrate produced and our liver and mitochondria, the rest (acetate, propionate). Hydrogen (H2), carbon dioxide (CO2), sulfur (H2S-- often smelly), and methane (CH3 -- scentless) determines the population shifting because they are actually 'food' for somebody in the zoo.

Test...don't guess.

Flint et al JAM, 2007
GUT: Black Box of Metabolic Crossfeeding

Nature Abhors a Vacuum; So Does Your Gut

Don't take raw resistant starch alone -- Consider taking the entire spectrum of fiber and cooked + raw resistant starch to feed the entire village in our gut, not just the RS2 eating ones. It takes an entire village to make a healthy host.

I love the biohacking on the gut that Tim Steele has done! His gut is really optimal in many respects I'll review. To me it is an excellent example of the power of food and food therapy. Please see his gut testing blogpost on how the uBiome test showed that with real food, cooked-cooled RS3 appeared to help more ANCESTRAL CORE MICROBIOTA TO BLOOM. The ancestral core is a great reference point because these are the core strains found in non-diseased, low inflammation, healthy European adults. His results require confirmation (the simultaneous AmGut is pending).

Nice QS n=1 Experimentation

Gut Microbe

Genus Level

ANCESTRAL

CORE

BETTERGUT DIVERSITY?20-40g RS3

for 6 wks

Real Food

(uBiome)

Tim's Results

uBiome Normal

Average

SUBOPTIMAL

SKEWED GUT DIVERSITY?

20-40g RS2

for 1 year

Potato Starch

(AmGut)

Tim's Results

F. prausnitzii

17.2%

9.3%

4.8% ?suboptimal

Roseburia**

14.7%

3.4%

0.41%?suboptimal

Eubacterium

0.8%

0.9%

0.1%?suboptimal

Bacteroides

10.2%

9.4%

46.2%(?suboptimal)

Bifidobacteria

8.81%

.88%

11.32%(?suboptimal, not B.longum)

Ruminococcus

3.2%

6.06%

13%(?suboptimal)

Switching from high dose RS2 to real food high RS3 not only preserved the Bifidobacteria but significantly and dramatically expanded several of the big butyrate factories, lean (twin study) biota and ancestral core [based on %relative abundunce, not sheer #].

Enriched in mice colonized with or invaded by members of a Ln microbiota:

Bacteroides uniformis* -- B. vulgatus is one of ancestral coreBacteroides vulgatus* -- one of the 7 ancestral coreEubacterium desmolans* -- E. rectale is one of the 7 ancestral coreParabacteroides merdae*Alistipes putredinis* -- one of the 7 ancestral coreRuminococcus callidusRuminococcus bromii -- one of the 7 ancestral coreClostridium symbiosumRoseburia unclassified -- one of the 7 ancestral coreClostridium ramosumAkkermansia muciniphila ~~high in hawwt, high lean mass rugby players w/lowinflammationRuminococcus obeumRuminococcus sp. 14531Eubacterium ventriosum -- E. rectale is one of the 7 ancestral coreBetaproteobacteria unclassifiedBurkholderiales unclassifiedetc

Personally I think comparing uBiome with AmGut is like comparing apples with oranges -- but let's take them for face value and see if they confirm published 16S rRNA study outcomes. The uBiome did not show any significant deficiencies when Tim dropped the PS. In fact, his superior gut responded very adequately and got even better.

Starches, inulin, oligosaccharides, beta glucan and RS3 all feed directly or crossfeeds to Roseburia, however, it seems to prefer a wide spectrum of fiber (except RS2). This was the major jump I think for VLC'ers and starch-free, low-carb Paleo diets. It is ironic because the whole spectrum of fiber makes us insulin sensitive and burn fat better. RS2 mildly does too but not to the high degree as inulin, glucomannan, whole (gluten free) grains, chana dal and legumes.

Fermentation of RS2 (green banana flour/version B or raw potato starch/version C) will be spread completely through the entire colon if taken with insoluble and soluble fiber. What counts? A fiber rich diet of 15-25 or more grams daily of rainbow foods (plants and fruits with diverse color polyphenols and antioxidants known as proanthocyanidins). Psyllium. Steel cut oats. LEGUMES OR WHOLE ROASTED POTATOES (which are paleo foods imho). Inulin rich foods are asparagus, artichokes/sunchokes, onions, chives, shallots, leeks, garlic, chicory, endive, many roots, and yacon. Every geographical area on earth has easy access to cheap inulin (fructan) rich foods. The natural human diet might be a FODMAP- and RS-rich diet for perfect gut health. Chart of FODMAPs.

I'm also a huge fan of Tim's guts. It superior in many respects.
--full spectrum of ancestral core present which are seen in the healthiest, non-diseased in Europe (Julien Tap's work); many of these strains I see 'missing' on many reports. He's got them.
--awesome stool pH
--no yeast
--no parasites
--no pathogenic bacteria (Shigella, Salmonella, Neisseria, Yersina, Proteus, Serratia, Kleb pneum)
--high butyrate and off the chart SCFA production (personal communication)

He can feed his gut prebiotic food and see many low frequency strains flourish and easily thrive. Perhaps certain guts are more reliant on certain strains than others. Every gut is different and testing is really the only accurate way to determine what's inside.

He reported GI/TMI problems on just food only, without supplementation of extra gut bug food (potato starch). After losing 100 lbs of fat and reversing every modern disease (Hashimoto's, diabetes, gout, fatty liver, obesity), his gut seemed suboptimal despite an awesome high RS3/fiber diet and years of weeding with frequent use of a high antioxidant botanical tea. I think Tim's gut maybe have felt the 4-fold drop in Ruminococcus bromii, just as VLC'ers had an observed 4-fold in Roseburia and subsequent vacuum of butyrate.

I think supplementation is good in this respect, even for a potato farmer with routine access to chicken coops, poops, manure compost, muddy root vegetables, homemade kvass and kefir!

"I will say that at about 2 weeks on the 'no PS' diet I noticed some changes in my digestion. I again had some minor smelly farts, my 'TMI' was a bit 'looser' than I like, and I was not quite as regular as I had become accustomed to. By the end of the 6 weeks, I was feeling fine digestion wise, but things were a tiny bit different--not bad, but different. I tracked FBG intermittently and found no big changes. Sleep stayed great.After the experiment, I went back to taking 2TBS of potato starch daily and within just a few days I was back to normal in the TMI department, nice, well-formed stools, and the gas went from 'silent but deadly' to 'loud but friendly.'"

Tuesday, September 16, 2014

"There were substantial differences between W-HAW and the other RS types. Changes in SCFA and pH were distributed more evenly through the large bowel in rats fed W- HAW. This may be of some value, because most chronic large bowel disease (including CRC) is localized in the distal colon and rectum, where SCFA supply is lowest (44). It has been suggested that a combination of RS plus nonstarch polysaccharide (NSP) is optimal in ensuring the supply of SCFA to these viscera (45). Our data support this, because HAW contained both fiber polysaccharides integrally, whereas the other diets (apart from W-LAW) required the addition of fiber." Conlon et al, 2012.

In healing the gut, rebiosis needs to occur -- reintroduction of lost life to a dysbiotic terrain. Nearly all health conditions being studied are now emerging with correlations to intestinal dysbiosis. And as we know by fixing dysbiosis, we can resolve many health conditions from allergies to autism spectrum to hypertension. Weeding, seeding, breeding and feeding are part of this cycle of rebiosis.

The loss of our microbial 'limbs' in the gut can likely be attributed to 5 main factors:

(5) distance and disconnection from the soil, good dirt teeming with microbes and unmolested by herbicides, pesticides, steam treatment, synthetic chemicals or petrol based fertilizers

Cooked RS3 is Ancestrally Derived

I think RS is a foundation fiber that our grandmothers forage and fired up on ancestral coals, primitive ovens and later village hearths. I think our ancestral mothers and caregivers fed all varieties of tender and tasty tubers, starchy roots, rhizomes and corms to toddlers and teens along with berries, stems, leaves, seafood and meaty bones.

RS3 and RS2 are vastly different in our guts. They feed different populations and even anatomically act differently in our gut tube.

RS3 acts like insoluble fiber, carrying fermentation way until the distal end of the intestinal tube, whereas RS2 acts like kindling, burning hot and quickly at the intestinal gateway, the caecum. Alone, raw resistant starch granules are rapidly eaten by intestinal flora and leave no residual to be fermented at your butt/rectum unless insoluble fiber and/or cooked RS3 are included at the same time in the diet.

Gut researchers Conlon, Topping and their team (above) discuss how their data supports that RS2 (high amylose maize) cannot supply butyrate or other SCFA to the distal gut without the mechanical structure of insoluble fiber, such as that found in wheat, wheat bran and insoluble wheat fibers [and again, no, I'm not advocating gluten or wheat].

I think a lot of people are benefiting from green banana flour and raw potato starch -- all fantastic sources of RS2 -- but make errors in trying to supplement a high RS2 dose or a dose that is deficient in supplying fuel and structure for the entire gut. The non-RS2 microbial eaters starve and eventually become extinct or become weak and outcompeted. They even lose their functionality in degrading different plant polysaccharides according to data about Ruminococcus bromii, the keystone degrader for both RS2 and RS3. According to Ze et al, at least 25% of healthy controls don't have R bromii or have defective R bromii that cannot use or eat resistant starch. TWENTY-FIVE PERCENT ARE F**KCED? Yes and what about the unhealthy? The obese? The pre-cancerous? The cancer survivors? The ones who took 6 months of antibiotics for acne or Lyme disease? The ones who have been following longterm Paleo? Strict AIP? Or ketotic very low carb (very low fiber/RS) diets? Or on one or couple courses of antibiotics for sinus infections, colds, fevers or urinary tract infections? The ones on acid blockers like H2 receptor antagonists or the "purple pill" PPIs?

Thursday, September 11, 2014

Earlier I had posted a science-driven presentation by Dr Tetyana Obukhanych, Ph.D. on Natural Immunity and Vaccination. She reviewed the literature (scanty) on the efficacy of herd immunity and the fallacies of protection, specifically how mothers are not conferring full and complete immunity against rare, but devastating whooping cough and measles to their newborns when breastfeeding. This is not ancestral and may have consequences. Additionally she reviewed the potentials of vaccine injury, including gut dysbiosis and multiple food allergies (peanut, gluten, dairy).

You may not have heard the news due to media censorship of the vaccine-autism debate, but apparently childhood vaccines can and do cause autism. Last month, a CDC Senior Scientist issued an apologetic press release admitting data omission from a 2004 study. The ditched data suggested African American boys are at increased risk of autism when given the MMR vaccine.

CDC's Director of Immunization Safety, co-author of the fraudulent 2004 study, has also admittedvaccines can result in autism. Moreover, autism is listed as side effect in the DTaP vaccinepackage insert.

Brian Hooker received the CDC confession directly from Senior Scientist, William Thompson. Hooker reanalyzed the data and found a 2.4x increased risk of autism in African American boys. The CDC states a lack of biological plausibility, but there's plenty.

Why would certain children be vulnerable to autism or any vaccine injury such as tic and seizure disorders? What makes them different from others who somehow escape injury?

First let's address gender inequality. Boys are up to five times more likely than girls to become autistic, perhaps because estrogen is crucial to immune response. Girls are primed at birth. But why African American boys? How tragic that over ten years ago the CDC decided this wasn't important enough to study further. How many African American boys have been damaged?

Other populations at risk of autism by vaccination include Koreans, Somali immigrants, perhaps much of Africa and Caucasians, too. Somali immigrants of Minneapolis and Sweden suffer high rates of autism when there is no word for "autism" in Somalia. In Sweden, they call it "Swedish disease."

Everyone on Earth is vulnerable to vaccine damage, but some populations appear especially at risk. These groups are different than others based on generations of dietary habits resulting in the underlying beauty of diversity: microbial predisposition. Their flora is naturally different!

Scientists have found gut microbiota play an important role in how well vaccines are absorbed. Imbalanced flora leads to vaccine failure. In sanitation-challenged, toxic nations such as Pakistan, for example, the polio vaccine can be ineffective due to compromised guts known asenvironmental enteropathy. How ironic that if we made sanitation and toxic pollution a priority, we could also reduce vaccination and its risk of injury. Instead, children suffer malabsorption syndrome misdiagnosed as malnutrition. They can't properly absorb nutrients or vaccines. Meanwhile, less than 2% of Bill & Melinda Gates Foundation budget goes toward improving sanitation; the lion's share toward vaccination in concert with major pharmaceuticals andGAVI. The United Nations, UNICEF and the World Bank promote wastewater treatment without any priority on the real solution of dry toilet technology.

One of the differences is reduced or absent bifidobacteria.

According to a Bangladeshi microbiota study published last month, poor vaccine efficacy is associated with systemic inflammation due to gut dysbiosis. Bifidobacteria were found a key factor in improving vaccine responsiveness. There are many known strains of bifidobacteria, some considered better than others. Bifidobacteria levels in the USA vary widely among individuals. Studies report muchlower levels of bifidobacteria in children with autism.

Vaccine scientists are focused on improving vaccine absorption, promoting probiotic adjuvants. Bifidobacteria appear to have a leading role as future adjuvant. But this work may also reveal a mechanism of vaccine injury: lack of an important species. Bifidobacteria are known to attenuatesevere intestinal inflammation. One study found their numbers naturally multiply in magnesium deficiency to calm inflammation.

Many Africans are missing bifidobacteria. And so are Koreans where autism rates were founddouble those in the USA. The traditional diet of these populations doesn't include dairy, which feeds bifidobacteria. It should be noted not all Africans are reduced or absent in bifidobacteria. Onestudy found bifidobacteria far more dominant in Malawian than Finnish infants while another studyfinds eightfold autism increases in Finland. Another vulnerable group appears to be vegans and vegetarians, known significantly reduced in bifidobacteria.

Breastfeeding is another important clue about bifidobacteria and autism avoidance. Breast milk is known to contain 700 types of bacteria with bifidobacteria the star of the show. Gerber includes bifidobacteria in their infant formula for good reason as "they make up 80–90% of the total intestinal flora of breastfed infants." Several studies indicate breastfeeding deters autism. What's not commonly recognized is how microbes both produce and stimulate release of fatty acids in breast milk crucial to brain development. These lipids include endocannabinoids now making waves in the epilepsy community (seizure is a common feature in autism).

A new study reinforces what's known about the global C-section epidemic and neurodevelopmental problems including autism. A third of women give birth by C-section in the USA, exceeded by other nations such as China and Brazil. C-section is known to result indifferences in infant intestinal flora, but what are the actual differences and how might this relate to potential for vaccine injury? This group of scientists found significantly lower bifidobacteria counts in C-section babies than in vaginally delivered infants. The bifidobacteria, however, are thought to originate in the mother's intestines.

Are girls higher in bifidobacteria than boys? Might this be another way girls escape autism? Recent studies reveal another way to view gender differences. Men and women can eat the same diet, but have distinctly different gut microbiota.

In the Hazda people of Africa, bifidobacteria is absent and so is dairy, however, some forms of resistant starch and inulin may also feed bifidobacteria. The Hazda microbiome is more diverse, so they don't require bifidobacteria. Other microbes are doing the job for their healthy human hosts, but perhaps not if confronted with vaccination.

Then again, the Hazda immune system may be better able to withstand vaccination than African Americans. The immune system is reliant on flora balance where gut dysbiosis, such as high clostridia, and low bifidobacteria counts may predispose a newborn toward vaccine injury. Alternatively, high clostridia counts known in autism may be the result of vaccination. Vaccines may lead to such imbalances, similar to antibiotics known to cause C. difficile infections.

The fact is there are still no studies about how any of the childhood vaccines affect flora balance. Why not? Does anyone fear the results? Solving this mystery may require crowdfunding. There are many complexities to be unraveled. How are mercury and aluminum adjuvants affecting flora? How might vaccine-induced immune responses affect flora balance?

There are a sparse few studies approaching the subject such as this 2004 study from China showing significantly increased gram-negative bacteria caused by the cholera vaccine, not a good thing. This 2013 typhoid vaccine study states:

"However, to date, no comprehensive studies have been undertaken to examine the gastrointestinal microbiota in relation to vaccine administration and if there is a discernible alteration in the community following vaccine administration."

How would a shift in flora or absent bifidobacteria lead to autism? This falls under the category of gut-brain phenomenon and probably begins in the womb. Dozens of peer-reviewed studies impudently state colonization begins at birth, a fallacy without evidence akin to believing Earth is flat. The new paradigm points toward a fetal gastrointestinal tract teeming with life, developing long before the fetal brain, even driving brain development with polyunsaturated fatty acids of microbial origin. The maternal microbiome shifts toward a diabetic state in the third trimester while the fetal brain triples in weight.

Children are born colonized and then vaccinated within 12 hours of birth per cruel CDC schedule without any understanding of how this affects flora balance. The gut-brain connection is a two-way street where what happens in the gut may lead to an inflammatory reaction in the brain.Bifidobacteria may be a factor in helping to avoid this reaction. Indeed, probiotics of many types have been tested alongside vaccines to improve vaccine response because it's known microbiotainfluence immune response. Might probiotics also help to avoid extreme immune response resulting in autism? Too many parents of autistic children have witnessed the arched back and high-pitched scream of their infants post-vaccination, a condition signaling brain inflammation.

I suspect bifidobacteria will become biomarkers to help avoid vaccine injuries. Every child would have microbial DNA (PCR) stool testing to determine flora balance prior to vaccination. If bifidobacteria are low or absent, this may serve as warning not to vaccinate. This applies to all children because everyone is at risk. Children may be born compromised with imbalanced flora where vaccines add insult to injury.

We should begin the process of reducing CDC vaccine protocol, beginning the protocol much later in life to allow the immune system, reliant on flora, time to develop. This would reduce vaccine injuries while improving vaccine effectiveness. Or, we can choose not to vaccinate and concentrate on improving innate immunity. Many believe our natural immunity is waning due to vaccination, so we're seeing a comeback of childhood diseases such as measles and mumps.

Either way, we need to reduce heartbreaking injuries as well as consider the subtle, insidious possibility of widespread flora shift in the wrong direction. We're already seeing mysterious childhood type-1 diabetes and obesity epidemics along with eating disorders such as anorexia in very young children. Half our children suffer chronic disease, an unacceptable situation where everyone is vulnerable based on flora balance.

Florida Congressman, Bill Posey, is investigating CDC fraud amid anincestuousrelationship with the pharmaceutical industry. Contact your Congressman to ask support for Posey's congressional hearings to learn more about extent of damage. The CDC "whistleblower" may receiveimmunityfrom prosecution so that underlying truth may finally be revealed, just as microbial genetic testing is taking us toward a new understanding of our place in the environment.

Keith Bell is a 25 year veteran of the recycling industry with interest in sanitation and health. During the 1980s, he was a UNICEF radio spokesperson in Chicago for the annual release of State of the World's Children Report. He’s particularly interested in gut-brain connection including gut-origin of seizure, underdiagnosed in epilepsy. Sanitation is Sanityposter

Wednesday, September 10, 2014

Many still hold beliefs against geoheliocentrism (kinda like the potential for vaccine injury and one among many reasons for possible subsequent gluten/dairy/food/peanut sensitizations and allergies... and epic gut disruptions, dysbiosis, metabolic problems, obesity...)

"Although virtually all scientists and most laymen now take Heliocentrism for granted, the human mind still has a tendency to accept and maintain any sense of closure it has already obtained based on seemingly obvious observations, rather than entertaining the possibility that those observations are misleading or entirely false. Consequently, a 1990's Gallup poll found that 16% of Germans, 18% of Americans and 19% of Britons still hold that the Sun revolves around the Earth, and a 2005 study found that one in five American adults still believe that. (Cited in Wikipedia’s entry for “Geocentric Model”)."

Tuesday, September 9, 2014

Ukrainian-born immunologist, Dr Obukhanych PhD is the author of Vaccine Illusion: How Vaccination Compromises Our Natural Immunity and What We Can Do to Regain Our Health. In her book, she presents a view on vaccination that is radically different from mainstream theories Dr Tetyana Obukhanych, has studied immunology in has studied immunology in some of the world's most prestigious medical institutions. She earned her PhD in Immunology at the Rockefeller University in New York and did postdoctoral training at Harvard Medical School, Boston, MA. and Stanford University in California.

She does talks for mom groups, practitioners and WAPF groups. I just saw her in SF on Sunday. She's absolutely wonderful and super brilliantly sharp!

Her view on the science is clear, concise and complete. Her intention is to illuminate the science, not perpetuate the public health fears. Facts v. fiction. The goal of the talk is to review: the facts, the theories, the choices.

"Facts without theory are nonsense. And theories without facts are b*llsh*t."

--Dr Obukhanych's favorite stat professor at Stanford

In her latest talk, she discusses some immunoprotective strategies and their mechanisms in health:

Monday, September 1, 2014

There is a new article in Nature about Neanderthals. My previous posts on them: here. I think they're an interesting group which overlapped with both Hss and Homo erectus (aka Java Man, aka Peking Man). I talked a ton about Homo erectus at the AHS14 talk because though we do not apparently have DNA data yet, he had such range and geographic breadth like Neanderthals, that there certainly likely existed co-mingled culture and blood between Hss and Homo erectus. New evidence appears to indicate we shared many things with Neanderthals for several thousand years... and their demise appears staggered over geography and time. I still wonder what diet, lifestyles and climate changes affected their extinction? They were cold adapted, surviving Ice Ages and interglacials. They grew rapidly during maturation and development, even more than there predecessors, almost like a vampirish subspecies. But, apparently something in the warmer climates laid claim to their eventually deaths as an independent native race. It's still a mystery. Too bad gut and intestinal tissues haven't survived the millenia for sophisticated analysis.

The timing and spatiotemporal patterning of Neanderthal disappearance

Part of abstract: The timing of Neanderthal disappearance and the extent to which they overlapped with the earliest incoming anatomically modern humans (AMHs) in Eurasia are key questions in palaeoanthropology1, 2. Determining the spatiotemporal relationship between the two populations is crucial if we are to understand the processes, timing and reasons leading to the disappearance of Neanderthals and the likelihood of cultural and genetic exchange.

Editor's summary

Did anatomically modern humans coexist with Neanderthals? Attempts to answer this question are complicated by the fact that conventional methods of radiocarbon dating become unreliable at just about the time in question: as sample ages approach 50,000 years little carbon-14 is left and it is difficult to obtain accurate measurements. Tom Higham and colleagues have worked to improve sample processing and accelerator-mass-spectrometry radiocarbon dating in order to construct a robust chronology based on the last appearances of the Mousterian tool culture — considered diagnostic for the presence of Neanderthals — from forty sites from Spain to Russia. The results indicate that Neanderthals disappeared at different times in different regions, with a significant overlap with incoming modern humans for around 2,600 to 5,400 years. Rather than a rapid model of replacement, this work suggests a complex picture in which cultural and biological interchange could have occurred between the two groups across a period of several thousand years.