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Either the juice or made into an oil or ointment, it is a great preserver of the sight, and an excellent help for theeyes cinara, &c artichokes they provoke venery, and purge by urine cichorium succory, to which add endive which comes after they arecold and dry in the second degree, cleansing and opening. They coolthe heats of the liver, and are profitable in the yellow jaundice, andburning fevers. Help excoriations in the privities, hot stomachs. Andoutwardly applied, help hot rheums in the eyes cicuta hemlock. Cold in the fourth degree, poisonous. Outwardlyapplied, it helps priapismus, the shingles, st anthony fire, orany eating ulcers clematis daphnoides, vinca provinca periwinkle hot in the seconddegree, essaything dry and binding. Stops lasks, spitting of blood, andthe menses consolida major comfrey, i do not conceive the leaves to be sovirtuous as the roots consolida media bugles, of which before consolida minima daises consolida rubra golden rod. Hot and dry in the second degree, cleanses the reins, provokes urine, brings away the gravel. Anadmirable herb for wounded people to take inwardly, stops blood, &c consolida regalis, delphinium lark heels.

Consequently, no furthercollections of samples were made 190 rep mass bd health, 1909, 41, 477 in 1912 pullen191 reported that he had prepared two specimens ofiodine ointment according to the british pharmacopeia, one beingfrom new lard and the other from a specimen of lard at least 2 yearsold assays for free iodine were carried out immediately after thepreparations were made, and at intervals afterward up to four months the following values were found:191 pharm jour , 1912, 89, 610 sample i sample ii ointment from ointment from new lard, old lard, per cent per cent iodine introduced 4 0 4 0 iodine found immediately after making 3 95 3 38 iodine found after twenty-four hours 3 30 3 15 iodine found on the third day 3 18 2 62 iodine found on the seventh day 3 15 2 46 iodine found on the fourteenth day 3 00 2 45 iodine found after one month 3 00 2 39 iodine found after two months 2 90 2 31 iodine found after four months 2 92 2 26pullen found that the loss in free iodine could be accounted for by theiodine which had gone into combination with the fats of the ointmentbase pullen custom essay papers also found that if the potassium iodide and glycerin wereomitted in the preparation of the ointment, the loss in free iodinewas very rapid, the preparation containing practically no free iodine only 1/20 after a few hours he concludes that the use of potassiumiodide and glycerin is necessary for the preservation of the ointment he obtained specimens of iodine ointment in drug stores, and assayedthem for free iodine it is to be presumed that the ages of the severalspecimens were not known the results are found in the following table. Specimen no 1 2 74 per cent specimen no 2 2 85 per cent specimen no 3 2 62 per cent specimen no 4 2 48 per cent specimen no 5 2 53 per cent specimen no 6 2 79 per cent fried192 prepared iodine ointment according to the u s p viiiformula, and assayed it at intervals his results are tabulatedherewith:192 pharm jour , 1912, 89, 610 per cent iodine introduced 4 00 iodine found immediately after making 3 89 iodine found one hour after making 3 51 iodine found one day after making 3 48 iodine found five days after making 3 06 iodine found ten days after making 2 84 iodine found thirty days after making 2 81 iodine found ninety days after making 2 81 iodine found eight months after making 2 81iodine ointment has been official in the u s pharmacopeia since 1870 briefly, the method now used for making the preparation is as follows. Four gm of iodine, 4 gm of potassium iodide and 12 gm of glycerin are weighed into a tared mortar and the mixture triturated until the iodine and potassium iodide are dissolved and a dark, reddish-brown, syrupy liquid is produced eighty gm of benzoinated lard are then added in small portions and with trituration after each addition the mass is then triturated until of uniform consistence 193193 the time required to complete the process after the initialportion of lard has been added should be about twenty minutes paraffins and paraffin preparations-- table a key. A.

The nature of this relation is unknown adiposis is a frequentsign of disturbed pineal function, but observers are not agreed whetherto interpret this as indicating hypofunction or hyperfunction, orpossibly a concurrent disturbance of the pituitary in essay instancesintravenous injections of pineal extract have seemed to cause adistinct fall in blood pressure it has been inferred from observationsin paper of pineal tumors in the young that the gland in youngindividuals furnishes a secretion which inhibits growth, writingicularlythe development of the reproductive glands, but the results ofexperimental administration of pineal substance orally have led otherobservers to infer that the pineal secretion favors physical andpossibly mental and sexual development it has been suggested that, asall evidence points to the fact that the function of the pineal glandis one of early life, extract of adult pineal glands might be expectedto be inert experiment has also indicated greater activity in glandsobtained from young animals than in those obtained from older ones thecouncil has decided to admit preparations of pineal gland to new andnonofficial remedies simply for experimental purposes red bone-marrowred bone-marrow consists largely more than 90 per cent of fat innew-born animals a third or more of this fat consists of lecithin the marrow of the bones of new-born animals contains iron up to 1per cent or more in various forms of organic combination bothlecithin and iron decrease rapidly in the first weeks after birth the commercial preparations contain very variable amounts of theseconstituents actions and uses -- red bone-marrow is supposed to stimulate theformation of red blood corpuscles. Whatever action it may have in thisdirection is probably due largely to the iron and lecithin which itcontains it is said to be useful in simple and pernicious anemias thymus glandlittle is known as to the functions of the thymus, but it is believedto have an important relation to growth there also seems to be essayrelation between the thymus and thyroid, for the former is frequentlyabnormal in diseases involving the latter hyperthyroidism the use of thymus is purely empirical it has been employed in thetreatment of hyperthyroidism, rickets, tuberculosis, hemophilia, andinfantile marasmus and atrophy. Its use in the latter conditionsis said to be the most promising it is claimed on very doubtfulgrounds to exert a essaywhat favorable effect in certain paper ofcancer -- from reports of council on pharmacy and chemistry, 1918, p 69 piperazine and lycetol omitted from n n r report of the council on pharmacy and chemistrythe following report explaining the omission from new and nonofficialremedies of piperazine and lycetol has been authorized for publication w a puckner, secretary piperazine diethylenediamene and lycetol a methyl derivative ofdiethylenediamene were accepted for new and nonofficial remedies in1906 both piperazine and lycetol were asserted to be efficient uricacid solvents and efficacious remedies in the treatment of gout andrheumatism these products have been retained until now because therewas no investigation which definitely showed their uselessness as uricacid solvents, though their use is generally admitted to have beendisappointing from an exhaustive and critical study of the available evidence, hanzlik jour lab & clin med , february, 1917 concluded thatscientific evidence, though limited, and clinical opinion indicate thatpiperazine is valueless in gout and that there is sufficient scientificevidence to indicate the worthlessness of lycetol the referee in charge of piperazine and lycetol recommended that theseproducts be omitted from new and nonofficial remedies for the reasonthat they have been sufficiently tried to justify the conclusion thatthey are not of value the period of acceptance having expired, thecouncil directed that piperazine and piperazine tablets the bayercompany, inc and lycetol the bayer company, inc be omitted fromnew and nonofficial remedies -- from reports of council on pharmacyand chemistry, 1918, p 70 stanolind liquid paraffin omitted from n n r report of the council on pharmacy and chemistryas explained in the report which follows, “stanolind liquid paraffin”was omitted from new and nonofficial remedies at the request of theproprietors announcement of this omission was made in the preface tonew and nonofficial remedies, 1918, but publication of the councilreport was postponed pending actual conflict with the rules thecouncil now authorizes publication of the report because a circularindirectly advertising the product to the public was found enclosedwith the trade package of stanolind liquid paraffin w a puckner, secretary stanolind liquid paraffin was admitted to new and nonofficial remediesin 1916, when its method of marketing conformed to the rules of thecouncil this brand of liquid petrolatum, by action of the council, has been omitted from new and nonofficial remedies on request of thestandard oil company of indiana, its manufacturer, who wrote to thesecretary of the council stating that. “in order that our facilities for the manufacture of this oil shall be constantly engaged, it will be necessary for us to find sales on a larger scale than in the past to do this under our present advertising and marketing arrangement we feel will be impossible ”this letter, in addition, suggested “that physicians are notprescribing stanolind liquid paraffin in any considerable proportionof their orders” and “that the situation which now confronts us wouldnot be materially helped if stanolind was specified in all suchprescriptions ” further, the council is asked to consider whetherit “might be willing to declare this preparation as not a councilproduct, ” on the alleged grounds that “liquid paraffin is not medicinalin its action and passes through the digestive tract in practicallyunaltered condition ”the council holds that stanolind liquid paraffin is a drug, and that, therefore, its direct advertising to the public is in contraventionof the council rules constipation should be treated by dietaryand hygienic means evacuants are only temporary measures liquidpetrolatum is medicinal. It greatly modifies the intestinal flora. Itacts as a lubricant and emollient. It modifies the absorptive powersof the intestinal mucous membrane. It is capable of influencing thedigestion of fats in short, liquid petrolatum, being a drug, itsindiscriminate and excessive use should not be encouraged -- fromreports of council on pharmacy and chemistry, 1918, p 72 westerfield digitalis tablets report of the council on pharmacy and chemistrythe council has adopted the following report and authorized itspublication w a puckner, secretary westerfield digitalis tablets the westerfield pharmacal co , dayton, ohio are claimed to represent a fat free tincture of digitalis and tobe “enteric coated ” it is claimed that because of this coating thesetablets pass the stomach unchanged and dissolve in the intestine, andthat this obviates any possibility of gastric disturbance the circular which sets forth the asserted advantages of the tabletsstates that digitalis contains a fat which is an irritant to thegastric membrane it also contains the following.

note the circular enclosed i have blue circled the remarks he evidently thinks will attract custom essay papers ”in may, 1919, chicago physicians received a form letter, signed, and on the stationery of, albert a lowenthal, notifying them thatdr lowenthal was about to “give a post graduate course of lecturesand clinics on nervous and mental diseases” in the “banquet hall, morrison hotel ” enclosed was a “programme and reservation card” anda self-addressed envelop for physicians to notify dr lowenthal thatthey would be present in addition to showing physicians “how to makediagnoses accurately, ” dr lowenthal offered to “explain fully how toscientifically check the christian scientists and increase your earningpower!. ” and all for nothing!. At later dates similar letters were received by physicians in othercities, on the stationery of the “american organotherapy company, room902, 31 north state st , chicago ” dr lowenthal, whose chicago officeis room 901, 31 north state st , is, apparently, president, treasurerand practical owner of this company enclosed with each of theseletters-- which offered the same inducements, free-- was an envelopaddressed to albert a lowenthal in care of the hotel at which dr lowenthal would stay while in that city there was also a “programmeand reservation card” as in the case of the letters sent to chicagophysicians according to our records, dr albert a lowenthal was born in chicagoin 1874 and was graduated by the college of physicians and surgeons, chicago, in 1895, receiving his license the same year in a leaflet issued essay time ago by albert a lowenthal, m d , “forthe sole purpose of enlightening prospective patients in regard tothe therapeutic value of the organo therapy treatment for nervousdiseases, ” we learn that dr lowenthal is, or was. “professor nervous and mental diseases, chicago hospital college of medicine ” “formerly professor nervous and mental diseases, dearborn medical college, jenner medical college ” “adjunct professor on neurology and psychiatry, university of illinois college of medicine ” “formerly physician illinois eastern hospital for the insane ” “formerly supt , riverview hospital for nervous diseases, kankakee, ill ” “formerly on advisory and associated attending staff cook county hospital ”in polk medical directory for 1904, dr albert a lowenthal nameappeared, under chicago, at 910-912 chicago opera house building he was described as “superintendent of lowenthal sanitarium ” inthe same issue of the directory, there was a display advertisementof the lowenthal sanitarium, which, while located at kankakee, ill , had its “main offices” at 912 chicago opera house bldg , chicago theadvertisement was headed “goat lymph treatment, ” and read in writing. “goat lymph has revolutionized medicine, and has been adopted by the scientific medical world as the only therapeutical agent that will absolutely bring about positive results in chronic conditions, such as neurasthenia, nervous collapse, paralysis, locomotor ataxia, brain fag, oncoming insanity, chronic stomach disorders, in fact such diseases needing cell stimulation ”it mentioned further that dr albert lowenthal “introduced goat lymphto the medical world as a curative agent ”a few years ago a chicago concern, known as the “american animaltherapy co , ” put out such products as “lymphoid compound lowenthal, ”“ova mammoid lowenthal, ” “prostoid lowenthal, ” etc the americananimal therapy co had for its manager james m rainey rainey alsooperated the “rainey medicine co , ” a mail-order “patent medicine”concern that sold “vitaline, ” a “general debility cure ” the rainey“vitaline” quackery was exposed in the journal, oct 1, 1910, and thematter appears in “nostrums and quackery ”when the american animal therapy company was operating from 84 adamsst , chicago, it claimed to have a hospital and laboratory at kankakee at the same time letters were being sent out on the stationery of“the lymph hospital, ” signed albert a lowenthal, m d although this“hospital” was at kankakee, ill , the address on the stationery was 84adams st , chicago, and its telephone number was that of the americananimal therapy company according to the stationery, the “medicaldewritingment” of the lymph hospital was “under the personal directionof dr albert a lowenthal, who introduced the lymph compound andlymphoid compound to the scientific medical world as a curative agentin chronic nervous conditions ” a layman received a letter from the“lymph hospital” urging him to take “lymphoid compound ” later hereceived a “follow-up” letter, from which the following extracts aremade capitals used as in the original:illustration. Essay letterheads greatly reduced of concerns in whichdr albert a lowenthal has been interested “do you know that the doctors of this country are using the lymphoid compound exclusively in all paper, where the nervous system is greatly involved, with the most marvelous results isn’t that sufficient proof as to the merit of the remedy?. ” “ nobody can tell you there is essaything just as good, because there is nothing just as good as the lymph-- in fact it is the only thing that can be depended upon ” “ our dr lowenthal gives his personal attention to all paper at the hospital and devotes a portion of his time advising by mail those persons under treatment who are unable to come to the hospital he is a man of world wide reputation in treating nervous diseases-- his advice on paper like yours is worth everything to you ” “think this over and if you do, you will write an order today for the lymphoid compound the home treatment costs $9 50 for thirty three days-- think of that you have our physician advice and care free of charge-- could anybody ofter more to you?. ”in 1908 dr lowenthal appeared as a witness for edward r hibbard, who was being prosecuted by the federal authorities hibbard operateda “men specialist” office in chicago. It had two entrances and adifferent name for each entrance-- the “boston medical institute” andthe “bellevue medical institute ” hibbard was found guilty of fraud inthe operation of this concern and was fined $1, 500 the transcript ofthe testimony in the hibbard case records that dr albert a lowenthal, when on the stand, claimed to “have treated as thesis nerve patients asany nerve specialist in chicago ” he further declared, according to thetranscript, that physicians who make a specialty of nervous diseases“mature in about ten years” and that after that time most of thembecome nervous wrecks or insane this was in 1908 in this connectionit is worth noting that in letters sent out by lowenthal in may, 1919, he claimed. “in the past twenty-five years i have limited my work to neurological and psychological paper ”in 1908 also, dr lowenthal was sending out letters to illinoisphysicians in his capacity as secretary of the “physicians’ league ofillinois ” the “league” issued a “report on candidates for governorand members of legislature, ” giving the names of the various politicalcandidates for office whom “the members of the league can safelysupport ” there were no “membership” fees and a physician who wroteasking “who foots the bills” received no reply in 1915 albert a lowenthal, whose “valuable discoveries in thedomains of organo therapy, neurology and pediatrics, have given him aninternational reputation as a neurologist, alienist and climatologicalexpert of high standing, ” was “medical superintendent” of the “nationalsanitarium information bureau ” this purported to represent the“leading sanitariums and health resorts in the u s ” the “bureau”expected to make its “profit from the 10 per cent honorarium receivedon every referred patient ” the “business manager” of this concern wasone hubert miller, m d the following advertisement appeared in theclassified dewritingment of the st louis post dispatch in 1915:illustrationa layman who wrote in answer to this advertisement received a letterfrom dr lowenthal in which he said that it was his intention to takeabout thirty patients south with him for four months-- cost of trip$500, which includes medical treatment, board, etc dr lowenthalstated further. “i have treated probably more paper of locomotor ataxia and paralysis than any physician in united states and can honestly state that with organo therapy treatment your walk can be improved and pains controlled ”in march, 1919, dr lowenthal paid a visit to spokane, wash , andportland, ore a portland paper heralded his coming and printed apicture of “dr a a lowenthal, world famous alienist ” the paperdescribed dr lowenthal as “the alienist consulted in the harry thawcase” and the one “who treated john alexander dowie of zion cityfame and pope leo xiii ” the fulessay puffery that dr lowenthal gotwhile in spokane drew criticism from one or two members of the localmedical profession, who wrote to the newspapers protesting one ofthe physicians who thus wrote declared that lowenthal “coming wasannounced in a circular sent through the owl drug company which isagent for the sale of products of an organo-therapy company ”apparently, it was after dr lowenthal return from the pacific coastthat he commenced to announce his “post-graduate course of lectures andclinics” to the physicians of chicago, denver, st louis, columbus, etc -- and, incidentally, to bring to the attention of the medical worldthe alleged virtues of the products of the american organo-therapycompany -- from the journal a m a , july 3, 1920 medical society of the united states from “division of fees” to “down with autocracy”the “medical society of the united states” has for its “honorarypresident” one a h ohmann-dumesnil, a m , m d , m e , sc d , ph d , and for its “secretary and treasurer” one emory lanphear, m d , c m , ph d , ll d as originally planned, the “society” seems to have beenbased on the idea of organizing the “fee-splitters ” in may, 1916, the birth of the organization was announced to the medical professionthrough a letter signed emory lanphear, written on the stationery ofthe “medical society of the united states ” even in its embryonicstate the society had a h ohmann-dumesnil, a m , m d , m e , for itspresident, and emory lanphear, m d , ph d , ll d , as its treasurer the letter read in writing. “we-- the majority of the medical profession-- who believe in division of fees i e , that the surgeon should not ‘hog’ the whole of a patient money and leave nothing for the family doctor, are no longer welcome in the a m a we are therefore organizing the medical society of the united states, which will not be conducted for the benefit of a few selfish egotists we would like to have you with us “it costs only $1 00 to join this covers dues for 1916, and includes expense for the beautiful certificate of membership suitable for framing, which you will receive on admission fill enclosed blank and return to me with $1 00 ”but presumably the idea of organizing on a basis of “fee splitting”did not make a hit, so the lure was changed today physicians areapproached with the plea that the “medical society of the unitedstates” will make the medical world free for democracy. It is, we areassured, a “society of protest against the autocracy of the a m a , ”and a “society of medical democracy ”membership costs “only $1 00 including the cost of a beautifulcertificate of membership ” no penalties or punishments are involvedfor belonging to other societies, and. “joining our body need not affect your membership in any other society-- even the a m a , if you wish to belong to it, and be ‘bossed’ by the ‘simmons gang’ ”the dollar for the “beautiful certificate” and membership is solicitedby means of circular letters signed “emory lanphear, ” coming from 3447pine st , st louis, mo , the address of what has been variouslycalled the “american polyclinic, ” the “american hospital, ” and later, the “german hospital ” the “surgeon-in-charge” of the “german hospital”is emory lanphear, m d , c m , ph d , ll d when running under thename of the “american hospital, ” lanphear solicited operative work ona “division of fees” basis, which, the general practitioner was told, meant that “you are to have 40 per cent of all fees received from yourpatients sent to our staff for operation or treatment ”with the change in name from “american hospital, ” to “german hospital, ”lanphear appealed for a “portion of your operative work on a basis ofpure reciprocity ” this “pure reciprocity” seems to have been a stillmore liberal distribution of the patient money, for from a 40 percent basis it was raised to an even fifty-fifty said lanphear, in aletter sent out a few months ago:illustration. The “medical society of the united states, ” wasoriginally organized on a basis of “fee-splitting, ” as is shown by thereduced facsimile of a letter sent broadcast in 1916, announcing thebirth of the new “society ” apparently, “fee-splitting” as a rallyingpoint did not bring in the desired returns, so today the “medicalsociety of the united states” is alleged to be a “society of protestagainst the autocracy of the a m a ” “i wish also to inform you in spite of the despicable opposition of the hypocritical gang in charge of the a m a , and the no less contemptible action of the st louis medical society, i am going to remain in st louis and continue to do surgical work upon a ‘division of fee’ basis to be more explicit, if you bring me a case for operation i shall allow you one half of the fee for your time, trouble, responsibility and help in the management of the case ”before leaving the interesting professional personality of lanphear, and carefully avoiding any details of a personal nature, we may remindour readers that as long ago as 1908 lanphear was the “dean” of the“hippocratean college of medicine, ” with a h ohmann-dumesnil, a m , m d , m e , sc d , “vice-dean ” at that time lanphear sent out lettersto physicians proposing the organization of a “post graduate faculty”on the following basis. “those who hold full professorships shall purchase stock in the corporation to the amount of $1, 000 00. Those who become lecturers or instructors shall pay in the sum of $500 00. Those who are to be merely clinical assistants will buy ten shares of stock, $100 00 ”the “hippocratean college” was a “sundown” affair. It never graduated astudent, and expired in 1910 illustration.

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Nh₄i, a nitro hydrate iodide. Nh₄i₂, a nitro hydrate iodate. And nh₄i₂i₂, per iodide, a molecular compound, which i claim, they all being of a nh group, so what can be the objection of nitrogen hydrate of iodine?. of course when your chemist, with the aid of heat, drove off all the iodine, he naturally brought it back to a nh₄i there where he gets the a m i claim a molecular compound the oil of iodine i sent you by mistake was a 1 per cent and not a 5 per cent as marked i claim it is made from the resublimed iodine in mineral oil and not the b iodine i claim a 5 per cent has heretofore never been accomplished, so i therefore can claim essaything new tr iodine contains alcohol and potash as a base, the alcohol a dehydrater and potash an escharotic, and all other soluble iodines like the tincture have a metallic base mine has not my iodine is compatible almost with all the salts, alkaloids, tannates, and even the metals you can’t say that for the tincture or the others now why should mine not be superior to others?. preparations as yet are not on the market and a few pamphlets were printed to meet with the requirements of your rulings and approval and shall be corrected if we only can agree on a proper name as you may suggest yours very truly, the b iodine chemical co by john bohlander, a m, m d p s we are sending you under separate cover another sample of the oil of iodine which is a 5 per cent solution, and allowing for deterioration will test at least four per cent the referee in charge of the preparations submitted the above letter tothe council with the following comments:the principal statements in the letter are essentially erroneous ormisleading. Mixtures or double salts of ammonium iodid and iodin werenot discovered by dr bohlander, and are nothing new watery solutionsof iodin by means of an iodid have long been known and used in the formof lugol solution there is no evidence that ammonium iodid is less irritating thanpotassium iodid on the contrary, ammonium salts are generally moreirritating than the corresponding potassium salts b iodine is notcompatible with alkaloids, but behaves essentially like lugolsolution the a m a chemical laboratory reports that the new sampleof b oleum iodine contains only 1 2 per cent of free iodin, insteadof the claimed amount it is therefore essaywhat weaker than the iodinpetrolatum prepared by the a m a chemical laboratory reportscouncil pharm and chem , 1917, p 88 however good dr bohlander intentions may be, the statements that hemakes about his products are misleading or erroneous, and the productsare ineligible for n n r -- from reports of council on pharmacy andchemistry, 1918, p 44 antithyroid preparations antithyroidin-moebius and thyreoidectin omitted from n n r report of the council on pharmacy and chemistrythe following report explaining the omission from new and nonofficialremedies of antithyroid preparations antithyroidin-moebius andthyreoidectin has been authorized for publication w a puckner, secretary new and nonofficial remedies, 1918, contains a discussionof “antithyroid” preparation and describes two of these:antithyroidin-moebius e merck, darmstadt, gerthesis and thyreoidectin parke, davis & company, detroit, mich the referee reported that these “antithyroid preparations” evidentlyhave not realized the expectations of their promoters, and are viewedwith skepticism by practically all critical clinicians consequently, notwithstanding the cautiously worded statements ofclaims made by the manufacturers of thyreoidectin, the council approvedthe recommendation that this preparation thyreoidectin be omittedfrom new and nonofficial remedies for conflict with rule 6 unwarrantedtherapeutic claims and rule 10 unscientific and useless articles antithyroidin-moebius had already been omitted because it was offthe market the council further directed that the general article“antithyroid preparations” be also omitted the council having adopted the recommendation of the referee, thyreoidectin is omitted from n n r , while the general articleappears below, as a matter of record:antithyroid preparations are obtained from the blood or milk ofanimals, after the removal of the thyroid glands the use of these preparations is based on the theory that the thyroidgland secretes products which are toxic, but which neutralize and areneutralized by, other toxic substances produced elsewhere in the body removal of the thyroid glands would then lead to the accumulation ofthese second toxic substances as evidenced by the phenomena of cachexiastrumipriva and myxedema on the other hand, the blood or milk ofsuch animals is claimed to be capable of preventing the effects ofhypersecretion of thyroid substance, such as is supposed to occurin hyperthyroidism basedow or graves’ disease-- generally calledexophthalmic goiter these views are largely hypothetical. Attempts to give to them arational experimental basis have failed, but essay clinical observersreport distinctly beneficial results in the milder forms of thediseases, and in obscure nervous disorders which are supposedlyconnected with thyroid hypersecretion from the administration ofthe milk from thyroidectomized goats and also from the use of theproprietary blood preparations listed below the value of thesepreparations is very doubtful the reported improvements may only bepsychical or due to associated measures, as is often seen in thisdisease other measures of treatment should not be neglected improvement is said to occur in two or three weeks and to be indicatedby an amelioration of the nervous symptoms, tremor, palpitation, insomnia and excitability the administration must be long continued oral and hypodermicadministration are said to be equally effective, but the former isusually preferred these preparations are not known to be toxic, evenwhen very large doses are used -- from reports of council on pharmacyand chemistry, 1918, p 50 cephaelin and syrup cephaelin-lilly omitted from n n r and syrup emetic-lilly not accepted report of council on pharmacy and chemistrythe council has authorized publication of the following report, whichexplains the omission of cephaelin and syrup cephaelin-lilly from newand nonofficial remedies and the non-acceptance of syrup emetic-lilly w a puckner, secretary new and nonofficial remedies, 1918, describes cephaelin an alkaloidobtained from ipecacuanha root and lists syrup cephaelin-lilly containing 0 088 gm cephaelin hydrochlorid per 100 cc as apharmaceutical preparation of it the period of acceptance for syrup cephaelin-lilly having expired, eli lilly & company were asked to send the current advertising andlabels so that the council might determine if the acceptance of thispreparation might be continued in reply the firm wrote. “we have changed the name syrup cephaeline to syrup emetic but the product remains the same as before we have no circulars describing syrup emetic and can only send copies of the label ”the new name “syrup emetic” conflicts with the rules of the councilin that it does not indicate the potent ingredient of this simplepharmaceutical preparation and in that it is therapeuticallysuggestive emetics are powerful agents, and physicians should be givenevery opportunity of knowing what they prescribe for the purpose the name being in conflict with rule 8, the council voted to omit syrupcephaelin-lilly and not to accept syrup emetic-lilly as the cephaelin syrup was the only preparation of cephaelin admittedto new and nonofficial remedies, and as the alkaloid appears to have noimportant therapeutic field, the council directed that the descriptionof cephaelin also be omitted -- from reports of council on pharmacyand chemistry, 1918, p 52 colalin omitted from n n r report of the council on pharmacy and chemistrythe following report explaining the omission from new and nonofficialremedies of colalin has been authorized for publication w a puckner, secretary colalin is a bile salt preparation claimed to consist essentially ofhyoglycocholic and hyotaurocholic acids it is manufactured by rufuscrowell and company, essayrville, mass , and marketed by schieffelin andcompany, new york an examination of the current advertising by the referee of the councilin charge of bile salt preparations having revealed that claims weremade for colalin which were not in harmony with the known action ofbile preparations, schieffelin and company were informed that in theopinion of the referee the colalin circular matter required radicalrevision in this communication the referee objections to the claimswere set forth in detail no reply to this letter was received, and hence a copy of the letterwas sent to schieffelin and company and also to rufus crowell andcompany with the explanation that unless the statements in the colalinadvertising which the referee had questioned were substantiated bysatisfactory evidence, were suitably revised, or else the advertisingmatter withdrawn pending revision, the referee would be obligedto recommend to the council that colalin be omitted from new andnonofficial remedies in reply, schieffelin and company wrote that they were not “engagedactively in the introduction of colalin, ” and agreed to the omission ofcolalin from n n r in view of the failure to substantiate the claims objected to or anagreement to discontinue them, the council directed that colalin andcolalin tablets be omitted from new and nonofficial remedies forconflict with rule 6 unwarranted therapeutic claims the following are the claims which the referee questioned. “colalin embodies the physiological function of the bile in the intestinal canal and also possesses properties of its own which are intimately connected with the function of the liver ”the quotation implies that colalin has properties essentially differentfrom those of bile salts, a claim which requires substantiation “in the liver its action seems to be that of a general stimulant of all the hepatic functions ”this is a claim which requires substantiation “by the introduction of colalin it has therefore become possible to actually utilize the bile for therapeutic purposes ”this is an unwarranted claim, for bile was used therapeutically beforecolalin was introduced “as gall-stones are chiefly composed of cholesterin, experiments were made to determine whether colalin would dissolve these concretions outside of the body these were completely successful and were then followed by an extensive series of clinical investigations on persons suffering with cholelithiasis, which demonstrated that by the administration of colalin in thesis instances gall-stones were evacuated by the natural passages and their further formation prevented without resort to surgical intervention ”this is misleading in that the context shows that “without surgicalintervention” is meant to imply a connection between the experimentsshowing the solvent power of colalin and the passage of concretions “ colalin not only acts as a solvent of cholesterin calculi, but prevents their further formation by removing the causes upon which their development depends ”this conveys the impression that such solvent action is exerted inthe body, that is, that such concretions in the gallbladder may bedissolved and evacuated by the use of colalin for this claim there isno evidence “to understand the value of colalin in intestinal disorders it is necessary to bear in mind the important functions of the bile in the intestinal canal, namely, its writingicipation in the digestion of fats, its antitoxic action, and its influence upon the peristalsis ” “ through its antiseptic influence inhibits the production of toxins in the intestines ”the referee believes that there is no satisfactory evidence that bileor bile salts can inhibit the production of toxins in that writing of theintestine-- the colon-- in which they are commonly produced -- fromreports of council on pharmacy and chemistry, 1918, p 52 foral report of the council on pharmacy and chemistrythe following report on foral, a depilatory preparation, has beenauthorized for publication by the council w a puckner, secretary foral is sold by the foral products company, pittsburgh, pa , as an“antiseptic depilatory” with the special claim for its use for theremoval of hair prior to surgical operation or the dressing of wounds in addition to claims made for its hair dissolving action, it isasserted that, in removing the hair from an open wound, foral acts as“an antiseptic, which guarantees against any infection ” it is alsoclaimed that, though hair will return after its use, “by proper useit will diminish the growth of hair and cause the hair to grow muchslower, and unlike the razor, the hair will not return coarser andthicker ”we are informed by the foral products company that their preparation isused in thesis hospitals and that “ one and all are well pleased and agreat satisfaction to do away with the old style razor ”foral is stated to be made according to the following formula. To manufacture seventy-five pounds of foral starch 35 pounds barium-sulphide 20 pounds zinc-oxide 10 pounds calcium-carbonated-precip 10 pounds potassium-permanganate 10 grams menthol-crystallized 10 grams carbolic-acid 1/2 ounce lilac or citronel oil 3 ounces the four above chemicals are going to a heating process before mixing or sifting in consideration of the preceding, the council declared foralinadmissible to new and nonofficial remedies for conflict with itsrules, thus:1 foral is an unessential and irrational modification of anestablished article while its manufacturer states that foral has been on the market foreighteen years, the following depilatory formula appears in a bookpublished thirty-five years ago a practical treatise on diseases ofthe skin, louis a duhring, ed 3, 1883 and is to be found in mostbooks on dermatology.