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Do You Need to Incorporate Live-Cell Imaging Systems in Your Laboratory? Check Out the Latest in Current Protocols in Cytometry

In this post-genomic era, the predominant focus of biomedical research has moved towards elucidating the functionality of molecules at the cellular and subcellular level in integrated living systems. As such, biologic imaging has moved beyond the collection of static “snapshots” of the cellular state to the real-time visualization of cellular and molecular behavior in three-dimensional (3D) space. Live-cell imaging techniques can be used to assess protein abundance, as well as determine the functional role(s) and interactions of multiple unique molecules concurrently within the cellular environment, and determine the effects of these molecules on cell development, organization, and fate over extended periods of time. Such studies require advanced systems that allo multiparametric analysis of cells while maintaining their functional viability.