Varlitinib for cell activation

Varlitinib for cell activation is available 2
times from
Biovision labs

2656-5
| Varlitinib for cell activation
size: 5 mg
| 248.65 USD

2656-25
| Varlitinib for cell activation
size: 25 mg
| 822.03 USD

Description
Varlitinib is a potent inhibitor of the epidermal growth factor receptor (EGFR) family with potential antineoplastic activity. Varlitinib selectively and reversibly binds to both EGFR (ErbB-1) and Her-2/neu (ErbB-2) and prevents their phosphorylation and activation, which may result in inhibition of the associated signal transduction pathways, inhibition of cellular proliferation and cell death. EGFR and Her-2 play important roles in cell proliferation and differentiation and are upregulated in various human tumor cell types. Due to the dual inhibition of both EGFR and Her-2, this agent may be therapeutically more effective than agents that inhibit EGFR or Her-2 alone.

Peptide sequence
N/A

CAS number
845272-21-1

Molecular weight
466.94

Category
Biochemicals

Other name
(R)-N4-(3-chloro-4-(thiazol-2-ylmethoxy)phenyl)-N6-(4-methyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine