Atypical Endocervical Cells (NOS)
Pictured is a sheet of endocervical cells with slightly disordered architecture, slight depth of focus to group, abundant cytoplasm, uniform, bland chromatin pattern and prominent nucleoli in each nucleus. The diagnosis of atypia may arise due to depth of focus to the group and slightly disordered architecture. Biopsy - Inflammatory Atypia - 60X

Atypical Endocervical Cells (NOS)The specimen contains a rounded up (3-dimensional) group of endocervical cells with slight disruption to architecture. Nuclei are all similar in size and nuclear membranes are smooth to slightly irregular. Biopsy - Chronic Inflammation - 60x

Atypical Endocervical Cells (NOS)
Nuclei contain single to multiple nucleoli that are small to moderate in size. Biopsy - Decidual changes - 60x

Look Alikes for Atypical Endocervical Cells (NOS)

Endocervical Repair:

Cell Type: Endocervical

Tissue Presentation

Flat, loose sheet

Look Alike for Atypical Endocervical Cells (NOS)
Repair - Note the flatness of this sheet of reparative cells. All of the nuclei are in the same plane and lack the nuclear crowding characteristic of AIS. Nuclei are uniformly spaced and round to oval, rather than elongate. 40x

Look Alike for Atypical Endocervical Cells (NOS)
This tissue fragment of lower uterine segment is composed of small, cuboidal cells with uniform nuclei and bland chromatin. At low power the cells appear crowded; however on closer inspection they are simply tightly packed. The cohesiveness and uniformity of such fragments at low power are the keys to diagnosis. A stromal component is usually present as well and is an aid in diagnosis. 20x

Look Alike for Atypical Endocervical Cells (NOS)
Nuclear elongation is clearly evident in this group of atypical endocervical cells. Also noted is loss of nuclear polarity, loss of normal architecture, nuclear crowding, and "molding" of the nuclei. Note the flat nuclear membranes where they push up against each other (a sign of true crowding). Biopsy - AIS - 60x

Look Alike for Atypical Endocervical Cells (NOS)
AIS - This crowded, stratified group of glandular cells comes from a case of AIS. Note the basal nuclei piling up from the lower layer of the epithelium. 60x