A definition of the medical term "goitrogen" is presented. Goitrogen refers to the substance that produces massive enlargement of the thyroid by inhibiting iodide metabolism and thyroid hormone synthesis. The term originated from the word "guttur" which means throat and "gennan" to produce. The...

An encyclopedia entry for "goitre" is presented. This is the enlargement of the thyroid gland, which causes a visible swelling a the base of the neck. Goiter is a deficiency of iodine, an element that the thyroid needs in order to produce thyroid hormone. Blood tests and radionuclide scanning...

The history of the association of goiter and orbital disease is discussed. Although Graves and Basedow are credited with the first descriptions of this association, it was described many years earlier between AD 1000 and 1110 by two Persian physicians and philosophers, Avicenna and Al-Jurjani.

Investigates the changing iodine intake and the effect on thyroid disease in Great Britain. Manifestations of iodine deficiency; Prevalence of non-toxic goiter and hyperthyroidism; Resistance of patients to carbimazole.

The article presents a case study of several patients who developed hypothyroidism and goiter after being exposed to penicillamine. The first patient received the drug for treatment of Wilson's disease for 15 years, delivered two babies who were noted to have goitrous hypothyroidism after being...