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Amyotrophic lateral sclerosis is a neurodegenerative disorder, which is characterized by progressive upper and lower motor neuron signs and symptoms, resulting in progressive muscle weakness. There are very rare reports of magnetic resonance imaging (MRI) abnormalities within the nerve roots or plexus reported in amyotrophic lateral sclerosis. Here, we report a patient who presented with progressive left arm weakness and was found to have bilateral MRIplexus abnormalities. This report illustrates that MRIplexus abnormalities can be seen in amyotrophic lateral sclerosis, possibly before symptoms, and may have clinical value in the diagnostic process.

*Mayo Clinic School of Medicine, Rochester, MN;

†Mayo Clinic School of Graduate Medical Education, Rochester, MN;

‡Division of Musculoskeletal Radiology, Departments of Radiology and Neurologic Surgery, Mayo Clinic College of Medicine & Science, Rochester, MN; and