Speaking to TV Guide, Tamblyn explained that Martha will leave because of one of her actions.

"She's going to potentially break one of her own rules in a very interesting way that is going to divide her," she said. "And it's going to break Masters a little bit, which will be really interesting to see because she's kind of been unbreakable."

"Katie Jacobs, who is the executive producer of House, approached me about this idea and I loved it," she said. "Ed Burns, who is the co-creator of The Wire with David Simon, is writing it and we just sold the idea to Fox. Hopefully we'll be making a pilot. It's about a young teacher set in the world of public education in America, which is kind of a touchy subject."

House airs on Mondays at 8/7c on Fox in the US and on Thursdays at 10pm on Sky1 in the UK.