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Context: An entertainment-education radio soap opera, Apwe Plezi, was broadcast from February 1996 to September 1998 in St. Lucia. The program promoted family planning, HIV prevention and other social development themes. Methods: The program's effects were assessed through analyses of data from nationally representative pretest and posttest surveys, focus-group discussions and other qualitative and quantitative sources. Results: Among 1,238 respondents to the posttest survey, 35% had listened to Apwe Plezi, including 12% who listened at least once per week. …