CD68/SR-D1 Antibody (KP1) [DyLight 550] Summary

Immunogen

Subcellular fraction of human alveolar macrophages

Localization

Cytoplasmic

Marker

Macrophage Marker

Specificity

This antibody recognizes a glycoprotein of 110kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.

Isotype

IgG1 Kappa

Clonality

Monoclonal

Host

Mouse

Gene

CD68

Purity

Protein A or G purified

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Applications/Dilutions

110 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage

Store at 4C in the dark.

Buffer

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Purity

Protein A or G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CD68/SR-D1 Antibody (KP1) [DyLight 550]

CD68 antigenmacrophage antigen CD68

CD68 molecule

CD68

DKFZp686M18236

gp110

Macrosialin

SCARD1

scavenger receptor class D, member 1

SRD1

SR-D1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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