Description

Buy JWH-018 online Buy JWH-018. (1-pentyl-3-(1-naphthoyl)indole) or AM-678[1] is an analgesic chemical from the naphthoylindole family that acts as a full agonist at both the CB1 and CB2 cannabinoid receptors, with some selectivity for CB2. Buy JWH-018 online

It produces effects in animals similar to those of tetrahydrocannabinol (THC), a cannabinoid naturally present in cannabis, leading to its use in synthetic cannabis products such as “legal cannabis herbal incense blends” which in some countries are sold legally as “incense”, labeled “not for human consumption” Buy JWH-018 online

Clinical data

Routes of
administration

Smoked, Oral

Legal status

Legal status

AU: S9 (Prohibited)

CA: Schedule II

DE: Anlage II (Authorized trade only, not prescriptible)

US: Schedule I

Identifiers

IUPAC name[show]

CAS Number

209414-07-3

PubChem CID

10382701

ChemSpider

8558143

ChEMBL

CHEMBL561013

ECHA InfoCard

100.163.574

Chemical and physical data

Formula

C24H23NO

Molar mass

341.45 g/mol

Solubility in water

hydrophobic, n/a mg/mL (20 °C)

InChI[show]

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JWH-018 is a full agonist of both the CB1 and CB2 cannabinoid receptors, with a reported binding affinity of 9.00 ± 5.00 nM at CB1 and 2.94 ± 2.65 nM at CB2.[3] JWH-018 has an EC50 of 102 nM for human CB1 receptors, and 133 nM for human CB2 receptors.[12] JWH-018 produces bradycardia and hypothermia in rats at doses of 0.3–3 mg/kg, suggesting potent cannabinoid-like activity. Buy jwh-018 online from chemplot.com and get free discreet shipping worldwide