Brosted acidic pyridinium-based ILs of [NS] [CF3SO3] and [NS] [HSO4] have been synthesized for oligomerization of isobutene with the excellent conversion of 92.8% and the good selective dimerization at the temperature of below 100 degrees C. Hydroxyl-containing materials, especially ethanol, could facilitate catalytic activities to excellent conver...

Brosted acidic pyridinium-based ILs of [NS] [CF3SO3] and [NS] [HSO4] have been synthesized for oligomerization of isobutene with the excellent conversion of 92.8% and the good selective dimerization at the temperature of below 100 degrees C. Hydroxyl-containing materials, especially ethanol, could facilitate catalytic activities to excellent conver...

Glycerol can be converted to valuable products such as epichlorohydrin which is an important intermediate applied in various industries. For example, dioxane derivatives, which are important pharmaceuticals, can be obtained from epichlorohydrin. In the present study, ZIF-8, ZIF-67, MIL-100, and UiO-66 were applied for the direct cyclodimerization o...

The interplay between the dopamine (DA) and opioid systems in the brain is known to modulate the additive effects of substances of abuse. On one hand, opioids serve mankind by their analgesic properties, which are mediated via the mu opioid receptor (MOR), a Class A G protein-coupled receptor (GPCR), but on the other hand, they pose a potential thr...

Aptamers represent interesting bioreceptor alternatives to antibodies when developing a bioassay and are selected by the Systematic Evolution of Ligands by Exponential Enrichment (SELEX) process. After selection, an extensive characterization process is essential to verify the binding affinity and specificity of aptamer candidates, which is the mos...

Myxovirus resistance 1 (Mx1) is an interferon-induced gene that encodes a GTPase that plays an important role in the defense of mammalian cells against influenza A and other viruses. The Mx1 protein can restrict a number of viruses independently of the expression of other interferon-induced genes. Mx genes are therefore considered to be an importan...

The new ferrocenylbis(oxazaphosphininone), [Fe{C5H4P(OC6H4)(CO) N-(C2H4Cl)}(2)] (1) was synthesized by the reaction of bis(dichlorophosphino) ferrocene with two equivalents of 2(2'-hydroxy) phenyloxazoline in the presence of triethylamine in 83% yield. The reactions of 1 with aq. H2O2 or elemental sulfur afforded bis-chalcogenides [Fe{C5H4P(E)(OC6H...

BACKGROUND: To recruit leucocytes to an inflammatory site, chemokine binding to glycosaminoglycans (GAGs) is critical. Therefore, strategies to interfere with this interaction, aiming at the production of anti-inflammatory agents, were developed. These include production of modified chemokines without affinity for G protein-coupled receptors but wi...

Although the N-terminal domain of vertebrate small heat shock proteins (sHsp) is poorly conserved, it contains a core motif preserved in many members of the sHsp family. The role of this RLFDQxFG motif remains elusive. We analyzed the specific role of the first arginine residue of this conserved octet sequence in five human sHsps (HspB1, HspB4, Hsp...