Today, her syndicated show is one of the longest-running call-in therapy shows in the United States. Until late 2012, it originated at WOR in New York. Browne takes a no-nonsense approach to callers, trying to home in on a problem without getting caught up in a caller's long stories or digressions. Browne is also known for her "one-year rule", which states that people who have lost a spouse or partner due to break-up, death, or divorce should wait at a minimum one-year before resuming romantic relationships. Dr. Joy is known for her phrase "stupid and cheerful" for dealing with difficult people. Browne has also half-jokingly suggested that people wait until they are 40 or 45 years old before having sex, due to the emotional nakedness involved, in addition to the physical.

Dr. Browne hosted a TV show on the Discovery Health cable channel in 2005 which was a live one-hour simulcast of her weekday show on WOR. She previously hosted a King World-Eyemark weekday syndicated TV advice talk show in 1999 for one year.

She has written numerous books on life and dating, including It’s A Jungle Out There Jane, Dating for Dummies,[2]The Nine Fantasies That Will Ruin Your Life, Capitalizing on Incompetence, Getting Unstuck, and Dating Disasters.