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I'm so sick of being nauseated on Plaquenil. 2 1/2 weeks in. Does it lessen? No vomiting, just pretty regular nausea. The taste from Xiidra drops def makes the nausea worse for a little while each day.

But let me tell you, the intense burning that occurs in my eyes every time I use the drops is so welcomed. A burn then my eyes feel better for a while. Always look forward to my next dose.

i take 2 200 mg tablets at night. Just try to eat something when you take them and hope the nausea passes. I’ve only been taking it 5-6 months. I don’t remember nausea but since I started taking plaquenil, I had a 2 week period of diarrhea, a month of severe joint swelling and pain in my knees, and now hives for the past 3 weeks. It appears to be helping with fatigue but seems to be triggering other things. I’m trying to stick it out until my next appointment.

I noticed an increase in fatigue too but it seems to be getting better. Just waiting for the next new issue to appear lol. Starting this med was a decision I put a lot of thought and consideration into and I decided I’d try it for at least 6 months (unless there was a major hurdle). I’m determined to keep at it.

I stopped taking it after over 3 years of stomach issues. All testing upper lower GI colonoscopy gluten intolerance etc all came back normal...so we stopped plaquenil and stomach issues decreased 80% at least.

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