Pirates of the Caribbean: Dead Man's Chest grossed $55.8 million on its opening day, setting records for the largest opening day, the largest single day gross, and the largest Friday gross of all time. The previous record was held by Star Wars Episode III: Revenge of the Sith with $50,013,859.

The Pirates of the Caribbean: Dead Man's Chest opening weekend gross stands at $135,634,554 which beats the previous all time opening weekend set by Spider-Man with $114,844,116. Even taking into account the fact that ticket prices were higher for this movie than they were when Spider-Man debuted, Pirates of the Caribbean: Dead Man's Chest still sold about 200,000 more tickets than Spider-Man did. The film is also the fastest to gross $100 million, doing so in just 2 days, as well as the fastest to gross $200 million, achieving that milestone in 8 days.

Pirates of the Caribbean: Dead Man's Chest has now grossed over $390 million worldwide and currently stands at #82 on the All Time Worldwide Highest Grossing Movies chart at Box Office Mojo.