Protocol C-05A Clinical Trial to Assess the Relative Efficacy of 5-FU + Leucovorin with or without Interferon
Alfa-2a in Patients with Dukes' B and C Carcinoma of the Colon

Specific Aims
The primary purpose of this study is to compare the relative efficacy of 5FU + LV with that of
5FU + LV + IFN-a2a in prolonging disease-free survival and survival of patients undergoing curative
resection of Dukes' B or C adenocarcinoma of the colon.