The investigators are doing the research to discover genes that cause Inflammatory Bowel Disease (IBD) specifically in the African American population. Who May Join This Study? Blacks / African Americans with or without Crohn's disease or ulcerative colitis.

If you agree to join the study, the investigators ask that you give us information about your health. The investigators will also ask you to give us a blood sample so that they may discover the genes that cause IBD. The blood sample may be collected at Johns Hopkins or any local facility convenient to you.

Blood samples from each participant will be sent to the NIDDK repository for DNA purification, sample distribution, establishment of cell lines. Serum samples will be sent to Fisher Bioservices Repository.

All additional samples will be processed and stored at Dr. Brant's Johns Hopkins IBD Genetics Laboratory with isolated lymphocytes and cell cultures made and stored at the Johns Hopkins Cell Center with use restricted to the PI (Dr. Brant).

Patients with IBD and their family members who have or do not have IBD.

People that do not have IBD are needed for comparison purposes.

Exclusion Criteria:

Patients whose IBD diagnosis can not be confirmed with medical records.

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01169194

Locations

United States, District of Columbia

Washington Hospital Center

Washington, District of Columbia, United States, 20010

Howard University Hospital

Washington, District of Columbia, United States, 20060

United States, Florida

University of Florida

Gainesville, Florida, United States, 32608

United States, Maryland

Johns Hopkins University School of Medicine

Baltimore, Maryland, United States, 21231

United States, Michigan

Henry Ford Hospital

Detroit, Michigan, United States, 48202

United States, North Carolina

University of North Carolina

Chapel Hill, North Carolina, United States, 27599-7032

Sponsors and Collaborators

Johns Hopkins University

National Institutes of Health (NIH)

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)