Specifications

Usage & Assay Information

Usage Recommendations

Optimal conditions to be determined by end user

Storage & Safety

Storage

Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles

General Information

Biological Significance

CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. Deficiency can cause Hyper-IgM syndrome type 3.