Fusion

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

IL1236

Sec-independent protein secretion pathway protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (72 aa)

Predicted Functional Partners:

tatB

Sec-independent protein secretion pathway protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (116 aa)

0.986

tatC

Sec-independent protein secretion pathway component TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (244 aa)

0.986

sufI

Multicopper oxidase (587 aa)

0.915

IL1237

Secreted metal-binding protein (163 aa)

0.859

copB

Hypothetical protein (247 aa)

0.834

IL2370

Sec-independent protein secretion pathway protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (73 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

IL1230

IL1231

IL1230

IL1231

Amino acid transporter

Hypothetical protein

0.790

IL1230

IL1236

IL1230

IL1236

Amino acid transporter

Sec-independent protein secretion pathway protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system

0.645

IL1230

IL1237

IL1230

IL1237

Amino acid transporter

Secreted metal-binding protein

0.741

IL1230

copB

IL1230

IL1234

Amino acid transporter

Hypothetical protein

0.802

IL1230

copC

IL1230

IL1233

Amino acid transporter

Hypothetical protein

0.741

IL1230

copD

IL1230

IL1232

Amino acid transporter

Copper export protein

0.741

IL1230

sufI

IL1230

IL1235

Amino acid transporter

Multicopper oxidase

0.799

IL1231

IL1230

IL1231

IL1230

Hypothetical protein

Amino acid transporter

0.790

IL1231

IL1236

IL1231

IL1236

Hypothetical protein

Sec-independent protein secretion pathway protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system

0.743

IL1231

IL1237

IL1231

IL1237

Hypothetical protein

Secreted metal-binding protein

0.905

IL1231

copB

IL1231

IL1234

Hypothetical protein

Hypothetical protein

0.885

IL1231

copC

IL1231

IL1233

Hypothetical protein

Hypothetical protein

0.946

IL1231

copD

IL1231

IL1232

Hypothetical protein

Copper export protein

0.955

IL1231

sufI

IL1231

IL1235

Hypothetical protein

Multicopper oxidase

0.844

IL1236

IL1230

IL1236

IL1230

Sec-independent protein secretion pathway protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system

Amino acid transporter

0.645

IL1236

IL1231

IL1236

IL1231

Sec-independent protein secretion pathway protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system

Hypothetical protein

0.743

IL1236

IL1237

IL1236

IL1237

Sec-independent protein secretion pathway protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system

Secreted metal-binding protein

0.859

IL1236

IL2370

IL1236

IL2370

Sec-independent protein secretion pathway protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system

Sec-independent protein secretion pathway protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system

0.800

IL1236

copB

IL1236

IL1234

Sec-independent protein secretion pathway protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system

Hypothetical protein

0.834

IL1236

copC

IL1236

IL1233

Sec-independent protein secretion pathway protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system

Hypothetical protein

0.746

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: