..To place these properties within a biological framework requires a theory based on a set of evolutionary and developmental principles. This paper describes such a theory, which aims to provide a unifying account of conscious phenomena...

..Applying measures of neural integration and complexity, together with an analysis of extensive neurological data, leads to a testable proposal-the dynamic core hypothesis-about the properties of the neural substrate of consciousness...

Connectivity and complexity: the relationship between neuroanatomy and brain dynamics

..The system described here prompts several hypotheses about the relationship between perception and motor control and may be useful in the development of general-purpose motor learning systems for machines...

..We hypothesize that adaptation to rich sensory environments and motor demands requires complex dynamics and that these dynamics are supported by neuroanatomical motifs that are characteristic of the cerebral cortex...

The brain-derived neurotrophic factor enhances synthesis of Arc in synaptoneurosomes

..The results demonstrate a correlation between the conscious perception of a visual stimulus and the synchronous activity of large populations of neurons as reflected by steady-state neuromagnetic responses...

A binding site for homeodomain and Pax proteins is necessary for L1 cell adhesion molecule gene expression by Pax-6 and bone morphogenetic proteins

..Given that some aspects of consciousness are likely to resist quantification altogether, we conclude that a satisfactory theory is likely to be one that combines both qualitative and quantitative elements...

BDNF induces widespread changes in synaptic protein content and up-regulates components of the translation machinery: an analysis using high-throughput proteomics

..Both of these viruses efficiently transduced neural stem cells isolated from embryonic rat hippocampus, and robust EGFP expression was observed in neurons derived from these cells following differentiation in vitro...

Differential regulation by multiple promoters of the gene encoding the neuron-restrictive silencer factor

..Although translation mediated by this IRES occurred throughout the cell, it was relatively more efficient in dendrites. These data suggest that IRESes may increase translation efficiency at postsynaptic sites after synaptic activation...

Biochemical and functional analysis of a 9-nt RNA sequence that affects translation efficiency in eukaryotic cells

..The data obtained by this model system provide direct evidence that ribosomal shunting can be mediated by mRNA-rRNA base pairing, a finding that may have general implications for mechanisms of ribosome movement...

BDNF induces translocation of initiation factor 4E to mRNA granules: evidence for a role of synaptic microfilaments and integrins