Objective: To study if the use of continuous glucose monitoritation systems in real time (GUARDIAN REAL TIME®) in the diabetic patients could improve the metabolic control.

Material and method: 15 type 1diabetic patients studied (age: 33.8±13.40, years of evolution: 17.06±11.32) in intensive treatment (5 multidoses, 10 insulin pump) which were made one first blind 4 days long monitoritation to them, PERIOD 1 (P. BLIND) with sensor CGMS Gold®. Next it was made another monitoritation with a real time system with glycemia and alarms of hyperglycemia and hypoglycemia, GUARDIAN RT®, PERIOD 2 (P. Real time). These 2 monitoritations were consecutive in each patient, establishing in the second period the levels of alarm of hypoglycemia in 50 mg/dl and hyperglycemia in 200 mg/dl. We studied in both periods: Average glycemia Glycemia Variability, Percentage of time in hiperglycemia (>180), normoglycemia and hipoglycemia (<70). A non-parametric test for matched up data was made (Wilcoxon)