The cartoon shows three "domes" in Jerusalem: (from left to right: ) the Church of the Holy Sepulchre, the Dome of the Rock, and a dome drawn as a large hand grenade, depicting the new “US Embassy” that opened in Jerusalem on May 14, 2018.

US recognition of Jerusalem as capital of Israel - On Dec. 6, 2017, US President Donald Trump formally recognized Jerusalem as Israel’s capital. Trump added that the final borders of Jerusalem will be determined during negotiations.
The US embassy opened in Jerusalem on May 14, 2018, the anniversary of Israel's declaration of independence in 1948 according to the Gregorian calendar.