Because both games rely on the same engine as Oblivion, which used floating point numbers even if the player only saw rounded whole numbers, it is highly likely that a source of water that goes (for example) from "1 Rad" pre-perk to "1 Rad" post-perk is still accurately treated internally i.e. 1 Rad versus .5 Rad.

At high levels this perk may become redundant; RadAway, Rad-X, and apparel with radiation resistance, such as power armor, become more available and readily obtainable.

In Fallout: New Vegas, there is an abundance of clean water, reducing the relative usefulness of the perk, although the benefit is extended to all irradiated food and water.

With the addition of Implant Y-3 in Old World Blues, this perk potentially becomes redundant, though is still available much earlier and for free. This perk also works on food and the implant does not.

Taking this perk on early may help out a lot as most manufactured food carries a lot of rads, and RadAway is scarce in the beginning. Conversely, this perk has little value for high-level characters because foods provide only a fixed amount of hitpoints (whereas Stimpaks restore a percentage). If you have two ranks of Solar Powered this perk is worth even less.

Although, with the introduction of the new survival mode where the player has to consume food and water all the time in order to survive, this perk still might be useful.