Given the dynamic nature of BOINC projects, i.e., multiple clients that may be viable depending on the science that is being conducted for any arbitrary project's WUs, it would facilitate things for project participants that utilize firewalls, HIPS applications such as Comodo Internet Security, if project developers would digitally sign their binaries with a certificate from a trusted CA.

The above URL is a link to a form that allows software vendors to request the addition of their software to the Trusted Vendor List that ships with Comodo Internet Security. This ensures their software will be automatically trusted by the application.

•Your software must be available for download by [Comodo] technicians
•Your software must be code signed with a certificate from a trusted CA (self-signed code signing certs are not acceptable)
•The 'Company Name' you provide below matches the name of the signer on the certificate
•You must provide a valid email address

there have been very few reports of false positives here. The end user is routinely told to add the BOINC folder to the AV ignore list. Its a very simple solution
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In a rich man's house there is no place to spit but his face.
Diogenes Of Sinope