Target

FunctionRecognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.

Sequence similaritiesContains 6 HMG box DNA-binding domains.

Post-translationalmodificationsPhosphorylated and activated by PIK3CA.