Zoloft and Insomnia

Zoloft and insomnia can be related. Insomnia is one of the more common side effects of Zoloft. If you suffer from insomnia while taking Zoloft, try following good sleep habits, such as avoiding caffeine four to six hours before you go to sleep, not exercising within two hours of bedtime, and not napping later than 3 p.m.

Zoloft and Insomnia: An Introduction

Insomnia is one of the most common Zoloft® side effects. Based on clinical trials of Zoloft (sertraline hydrochloride), insomnia occurred in up to 28 percent of people taking the medication. Insomnia was most commonly seen in people taking Zoloft for obsessive-compulsive disorder (OCD) -- up to 28 percent of people with OCD reported having insomnia with Zoloft. It was least common in those taking Zoloft for premenstrual dysphoric disorder (PMDD) -- 12 percent of women with PMDD reported experiencing insomnia while taking the medication.

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