Roger Clemens could face questions from a tougher interviewer than Mike Wallace.

The House Government Reform Committee yesterday invited former Yankees Clemens, Andy Pettitte and Chuck Knoblauch to testify on Jan. 16 about their use of steroids and/or human growth hormone, as alleged in the Mitchell Report.

If players do not agree to testify, they could be subpoenaed. The players’ former trainer, Brian McNamee, and former Mets clubhouse attendant Kirk Radomski also were asked to appear.

An appearance on Capitol Hill would give Clemens the chance to testify under oath that he never used performance-enhancing drugs. Clemens repeatedly has denied using the drugs since being implicated in the report by former Senate Majority Leader George Mitchell last month.

Clemens did not immediately accept or decline the invitation yesterday from the committee, which is chaired by Rep. Henry Waxman (D-Calif.).

“We welcome Chairman Waxman and the committee’s interest in this very serious matter,” said Rusty Hardin, Clemens’ attorney, in a statement. “Roger is willing to answer questions, including those posed to him while under oath. We hope to determine shortly if schedules and other commitments can accommodate the committee on that date.”

Pettitte’s agents did not return an e-mail seeking comment, and Knoblauch could not be reached.

Subpoenas were issued in 2005 when the same panel held hearings on steroid use in baseball and forced Mark McGwire, Sammy Sosa, Curt Schilling and Rafael Palmeiro to appear.

“We expect everyone will come voluntarily,” said Phil Schiliro, Waxman’s chief of staff. The hearing will occur one day after baseball Commissioner Bud Selig, union leader Donald Fehr and Mitchell appear before the committee.

The hearing will be in the same room used on March 17, 2005, for the hearing that shamed McGwire and featured Palmeiro’s finger-waving denial before he failed drug test two months later.

“It’s obviously a limited group of players, and it’s players that relate to Brian McNamee,” Schiliro said. “Mr. Clemens has raised issues about accuracy of the Mitchell Report, and that’s the purpose of this hearing, to find out more and to hear from all the relevant witnesses.”

McNamee trained Clemens, Pettitte and Knoblauch, and was employed by the Yankees as an assistant strength coach.

Facing the threat of federal prosecution, McNamee agreed to be interviewed by Mitchell. He told the former senator of injecting Clemens with steroids and human growth hormone. He also told Mitchell about injecting Pettitte and Knobluach with HGH.

Pettitte admitted to twice using HGH, but Clemens has vehemently denied McNamee’s allegations. Clemens is to appear tomorrow night on “60 Minutes” in an interview with Wallace, and plans a news conference Monday in Houston.

Richard Emery, one of McNamee’s lawyers, told the AP, “Congress is asking him to appear. In all likelihood, he will certainly appear.”

However, in an e-mail to The Post later in the night Emery said there was, “nothing definitive yet.”

Radomski pleaded guilty in April to felony charges of steroid distribution and money laundering. As part of his plea deal, he cooperated with Mitchell. He is set to be sentenced on Feb. 8.