Ignore Antigens for Antibody Biomarker Identification

Disease-specific antibodies that could be isolated from blood serum would make great diagnostic markers. But to date, few such antibodies have been identified. Now, a research team suggests that this may be because researchers have been looking for binding in all the wrong places  and showed that by using synthetic peptoids, they were able to isolate diagnostic antibodies for both an animal model of multiple sclerosis, and for Alzheimer's disease.