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Several themes were developed during the course of the symposium. These included the concept of “oncogene addiction” in which a cancer cell becomes “addicted” to it’s mutant oncogene, rendering it susceptible to induction of cell death by oncogene inhibitors. The role of the microenvironment in supporting tumor cell growth, and as a target for therapy was discussed. In addition to targeting of kinases in cancer, such as BCR-ABL, the potential for targeting the apoptotic machinery of cancer cells was present- ed by several investigators.

William Guy Forbeck Research Foundation

Established in 1985 by George and Jennifer Forbeck, from its inception the William Guy Forbeck Research Foundation has addressed its mission through a unique approach: by focusing on driving communications and collaborations between scientists and clinicians. Building these connections is a vital factor of advancing oncology research