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The company, which develops cures for early-onset life-threatening diseases, has emerged from stealth.

Gene-therapy company LogicBio Therapeutics, which develops cures for early-onset life-threatening diseases, has emerged from stealth to announce that it has raised $50 million in a financing round led by Arix Biosciences and with the particvipation of Edmond de Rothschild Investment Partners, Pontifax, and SBI Japan-Israel Innovation Fund.

LogicBio also announced that it has relocated it headquarters from California to Cambridge, Massachusetts. The company has R&D offices in Ness Ziona. The funds and move will enable the startup to continue development of its GeneRide technology, a first-in-class, proprietary genome-editing platform, and to accelerate its lead programs to the clinic.

“We’ve been able to demonstrate the breadth of our technology in proof-of-concept studies across multiple preclinical models,” said LogicBio President and CEO Frederic Chereau. “Conducted in collaboration with top-tier academic labs, these studies show that the GeneRide technology can provide stable, therapeutic levels of life-saving proteins after a single injection. We are passionate about taking the next step to deliver on the promise of this breakthrough technology for patients with early-onset rare diseases. In particular, we are focused on treating infants, which is a challenge for many gene therapies. And we’re excited to have such strong support from our investors to help us advance toward our goal of human proof-of-concept trials.”

“We’re pleased with LogicBio’s progress since seeding the company in early 2016,” said Erez Chimovits, senior managing director at OrbiMed Israel. “We believe that the well-differentiated platform technology addresses some significant shortcoming of episomal gene-therapy approaches. We welcome the new investors and look forward to advancing breakthrough therapies to the clinic.”

Published by Globes [online], Israel business news – www.globes-online.com – on June 28, 2017