“Bry went peacefully to Heaven,” Sparks’s mom, Jodi Jackson, wrote on Facebook Wednesday alongside a photo of her late step-daughter. “I can’t help to think [that] she’s smiling just like this. Thank you all for your prayers.”

Sparks, 28, first revealed Bryanna was suffering a sickle cell episode on Tuesday.

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Sickle cell disease is more common in certain ethnic groups, including:

– People of African descent, including African-Americans (among whom 1 in 12 carries a sickle cell gene) – Hispanic-Americans from Central and South America – People of Middle Eastern, Asian, Indian, and Mediterranean descent

But why is sickle cell so deadly?

Normally, your red blood cells are flexible and round, moving easily through your blood vessels. In sickle cell anemia, the red blood cells become rigid and sticky and are shaped like sickles or crescent moons. These irregularly shaped cells can get stuck in small blood vessels, which can slow or block blood flow and oxygen to parts of the body.

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Stroke. A stroke can occur if sickle cells block blood flow to an area of your brain. Signs of stroke include seizures, weakness or numbness of your arms and legs, sudden speech difficulties, and loss of consciousness. If your baby or child has any of these signs and symptoms, seek medical treatment immediately. A stroke can be fatal.

Pulmonary hypertension. People with sickle cell anemia can develop high blood pressure in their lungs (pulmonary hypertension). This complication usually affects adults rather than children. Shortness of breath and fatigue are common symptoms of this condition, which can be fatal.

Organ damage.Sickle cells that block blood flow through blood vessels immediately deprive the affected organ of blood and oxygen. In sickle cell anemia, blood is also chronically low on oxygen. Chronic deprivation of oxygen-rich blood can damage nerves and organs in your body, including your kidneys, liver and spleen. Organ damage can be fatal.

Blindness. Sickle cells can block tiny blood vessels that supply your eyes. Over time, this can damage the portion of the eye that processes visual images (retina) and lead to blindness.

Priapism. Men with sickle cell anemia can have painful, long-lasting erections, a condition called priapism. As occurs in other parts of the body, sickle cells can block the blood vessels in the penis. This can damage the penis and lead to impotence.

Because sickle cell disease symptoms can begin by four months of age, early diagnosis is critical. All newborns in the United States are now…