Tag: stem cell technology

Global Stem Cells Group and its affiliate AdiMarket announce the new Turn-Key Solution, a one-stop solution that provides high-quality stem cell processing equipment and kits and the expert help needed to set up a stem cell lab in-clinic or in-hospital.

MIAMI, Nov. 9, 2017—Global Stem Cells Group (GSCG) and its affiliate AdiMarket now offer a new, turn-key solution for stem cell processing. The AdiMarket Turn-Key Solution is a one-stop solution that provides high-quality equipment and kits required for stem cell processing and the expert help needed to set up a stem cell processing lab in-clinic or in-hospital. It can also be designed for complex protocols such as cryopreservation, culturing, and expansion of adult stem cells derived from adipose tissue and bone marrow.

GSCG and AdiMarket provide everything needed to bring this ready-to-go cell processing expansion lab to scientists andinstitutions worldwide. Physician training courses in the field of regenerative medicine are also available to qualified physicians. These expert training courses provide hands-on, practical instruction under the guidance of trained medical experts in a highly visual, interactive, and clinical learning environment.

The AdiMarket Turn-Key Solution is a complete solution for installing highly customized, in-clinic or in-hospital turn-key laboratories to meet each facility’s individual needs.

“A well-planned, organized, and properly equipped laboratory supports critical research and favorable procedure outcomes by increasing efficiency and reducing lost time and wasted resources,” says Benito Novas, Global Stem Cells Group founder and CEO. This is vital to continuing to the discovery and implementation of new methods for treating patients.”

Admarket is GSCG’s online marketplace for quality regenerative medicine equipment and supplies for physicians and health care professionals, offering all the tools and products practitioners need to facilitate in-office, in-clinic, or in-hospital stem cell procedures. From planning to building the lab, to training and consultation, Turn-Key Solution users are equipped in every way possible to walk in and begin using their fully-outfitted biotechnology lab.

Global Stem Cells Group (GSCG) is a worldwide network that combines seven major medical corporations, each focused on furthering scientific and technological advancements to lead cutting-edge stem cell development, treatments, and training. The united efforts of GSCG’s affiliate companies provide medical practitioners with a one-stop hub for stem cell solutions that adhere to the highest medical standards.

Global stem cell’s aim is to be the largest recognized stem cell and regenerative medicine network in the world.

About Adimarket:

Adimarket, Inc., a division of the Global Stem Cells Group, is a one-stop, cost-competitive online marketplace for quality regenerative medicine equipment and supplies for physicians and healthcare professionals.

Adimarket was founded to provide practitioners the tools they need to practice regenerative medicine in a medical office setting. Motivated by a firm belief in the impact stem cell medicine can have when dispensed in a doctor’s office, Adimarket provides physicians with the tools they need to provide patients with cutting-edge treatments.

Researchers at the University of Toronto have developed a tracer ink—a “stem cell tattoo”—that provides the ability to monitor stem cells in unprecedented detail after they’re injected.

The research findings, titled “Bifunctional Magnetic Silica Nanoparticles for Highly Efficient Human Stem Cell Labeling,” was published in June in the Journal of Magnetic Resonance Imaging. Already emerging as an ideal probe for noninvasive cell tracking, the technology has the potential to revolutionize stem cell research by arming scientists with the ability to visually follow the pathways and effectiveness of stem cell therapies in the body, in real time.

“Tattoo” tracer can help further development of stem cell therapies

University of Toronto biomedical engineering professor Hai-Ling Margaret Cheng, a biomedical engineer who specializes in medical imaging, says the new technology allows researchers to actually see and track stem cells after they’re injected. Cheng hopes the technique will help expedite the development and use of stem cell therapies.

Working with colleague Xiao-an Zhang, an assistant professor of chemistry at the University of Toronto, Scarborough, Cheng developed a singular chemical compound known as a contrast agent that acts as a tracer. Composed of manganese, an element that naturally occurs in the body, this tracer compound, called MnAMP, bathes stem cells in a green solution, rendering them traceable inside the body under MRI.

Stem cell tracer ink allows long term cell tracking

The contrast agent “ink” first enters a stem cell by penetrating its membrane. Once inside, it stimulates a chemical reaction that prevents it from seeping out of the cell the same way it entered. Previous versions of contrast agents easily escaped cells. By establishing a way to contain the ink within the cell’s walls, the research team achieved the ability to track the cells long term once they are inside the body.

University of Toronto professor Margaret Cheng holds samples of a chemical compound that will create a new way to visualize stem cells inside the body. (Photo: Bernard Weil, Toronto Star)

According to Cheng, some basic contrast agents are already available for use in humans, but none are capable of tracking cells over a long period of time. Contrast agents work by illuminating the deepest and darkest corners of a person’s internal architecture so they appear clearly under X-rays, computed tomography (CT) scans and MRIs. An example of a currently used contrasting agent would be the barium sulfate solution given to patients to help diagnose certain disorders of the esophagus, stomach, or intestines.

The thick substance coats the esophagus and other areas of the body with an illuminating compound, making them visible in an x-ray or CT scan. But the barium solution is eliminated from the body within 2 – 3 days or less. Before the stem cell tattoo tracer ink was developed, surgery was the only option for scientists to get a literal glance of a cells’ destiny after it was injected into the body. Now, researchers can track the results in real time, without resorting to any invasive procedures.

“Before, we could not visually track the cells once they were introduced into the body,” Cheng says. “Now we have the ability to view cells in a non-invasive manner using MRI, and monitor them for potentially a very long time.”

Cell tracer technology still in developmental stage

Currently the tracer ink technology is still in the early development phase and requires more animal testing. Cheng is hopeful it can proceed to human clinical trials in about 10 years. While Cheng has already proven that tattooing an animal’s embryonic stem cell doesn’t affect its ability to transform into a functional heart cell, rat, or even a pig (which better represents a human’s size), larger models are up for evaluation next.

In those test cases, researchers will cut off and reduce blood flow in the animals to mimic the effects of damage caused by a human heart attack. Cardiac stem cells pre-tagged with Cheng’s ink tracer technology will then be injected into the damaged tissue. Using MRI to monitor the luminous inked stem cells in action, researchers can non-invasively follow where in the body they’re traveling and more easily determine if the new cells are responsible for restoring normal heart rhythm.

Before it can be tested in humans, the chemical tracer will also have to pass rigorous toxicology tests to ensure its safety.