Derma-world

الخميس، 4 أغسطس، 2011

Hyperpigmentation is a common, usually harmless condition in which patches of skin become darker in color than the normal surrounding skin .

Hyperpigmentation may be caused by sun damage, inflammation, or other skin injuries, including those related to acne vulgaris. People with darker Asian, Mediterranean or African skin tones are also more prone to hyperpigmentation, especially if they have excess sun exposure.

Hyperpigmentation is associated with a number of diseases or conditions, including :

Addison's disease and other sources of adrenal insufficiency, in which hormones that stimulate melanin synthesis, such as melanocyte-stimulating hormone (MSH), are frequently elevated.

Cushing's disease or other excessive adrenocorticotropic hormone (ACTH) production, because MSH production is a byproduct of ACTH synthesis from proopiomelanocortin (POMC).

الخميس، 16 يونيو، 2011

A drug eruption is an adverse drug reaction of the skin. Most drug-induced cutaneous reactions are mild and disappear when the offending drug is withdrawn. Drugs can also cause hair and nail changes, affect the mucous membranes, or cause itching without outward skin changesAlthough most drug eruptions are exanthematous, different types of drug eruptions are described ...

diagnosed mainly from the medical history and clinical examination. However, they can mimic a wide range of other conditions, thus delaying diagnosis (for example, in drug-induced lupus erythematosus, or the acne-like rash caused by erlotinib). A skin biopsy, blood tests or immunological tests can also be useful. If the causative agent can not be withdrawn, the symptoms should be relieved as much as possible.

Rates of reactions to commonly used drugs are as follows:

Amoxicillin - 5.1%

Trimethoprim sulfamethoxazole - 4.7%

Ampicillin - 4.2%

Semisynthetic penicillin - 2.9%

Blood (whole human) - 2.8%

Penicillin G - 1.6%

Cephalosporins - 1.3%

Quinidine - 1.2%

Gentamicin sulfate - 1%

Packed red blood cells - 0.8%

Mercurial diuretics - 0.9%

Heparin - 0.7%

Cutaneous reaction rates in patients with HIV infection are as follows:

الخميس، 9 يونيو، 2011

Here is a continuation for the previouse blog ( Too much skin ! part 1)

these are a list of conditions that I joined togather because they have one thing in commen .. too much skin .. and below each condition a video related to the condition .

c) Diffuse hereditary palmoplantar keratodermas

is an autosomal dominant disorder in which hyperkeratosis is confined to the palms and soles, usually evident at birth or in the first few months of life.the they present in early childhood with redness of the palms and soles. The palms and soles gradually become thicker and develop a yellowish, waxy appearance. There is a clear cut-off between affected and unaffected skin and the edge of the thickening is often red. This is usually obvious by the age of 3 to 4

skin rapidly accumulates at these sites, which gives it a silvery-white appearance. Plaques frequently occur on the skin of the elbows and knee , but can affect any area, including the scalp palms of hands and soles of feet, and genitals .Psoriasis is not contagious and can be inherited. Environmental factors such as smoking, sun exposure, alcoholism , and HIV infection may affect how often the psoriasis occurs and how long the flare-ups last

الأربعاء، 8 يونيو، 2011

these are a list of conditions that I joined togather because they have one thing in commen .. too much skin .. and below each condition a video related to the condition

Here's a list of this conditions with a small comment on each :

a)Harlequin type ichthyosis

is the most severe form of congenital ichthyosis, characterized by a thickening of the keratin layer in fetalhuman skin. In sufferers of the disease, the skin contains massive, diamond-shaped scales, and tends to have a reddish color. In addition, the eye , ears , penis , and the appendages may be abnormally contracted. The scaly keratin greatly limits the child's movement. Because of resultant cracked skin in locations where normal skin would fold, it is easily pregnable by bacteria and other contaminates, resulting in serious risk of fatal infection.

very rare, with about 10 cases reported. The dermatosparaxis type is characterised by extremely fragile and sagging skin.The skin sags and wrinkles, and extra (redundant) folds of skin may be present as children get older. Joints are very loose, which can delay the development of motor skills such as sitting, standing, and walking. Infants with the condition are born with a hernia around the belly-button. Other symptoms include a small chin, a blue tinge to the sclera, and mild overgrowth of body hair.

Could this gentleman have dermatosparaxis type of Ehles-danlos syndrome ( he stretched his skin up to 14.2 cm away from his body!) :

الاثنين، 7 فبراير، 2011

Diabetes affects many organs in the body, including the skin. People with diabetes are more prone to skin problems, including dry skin, injection-related scarring that affects insulin absorption in the body, and vaginal infection. Because diabetes increases the risk for infection, even a minor skin condition can develop into a more serious problem.

Diabetes skin conditions generally fall into three categories :

Skin conditions that happen mostly to people with diabetes

Common skin infections made worse by having high blood sugar

Skin problems that occur from injecting insulin ( hypertropy or atrophy of the skin )

causes of diabetes-related skin conditions vary. Many are harmless, but it's helpful to recognize them and know when to see your doctor for treatment.

Diabetic dermopathy. this skin condition develops as a result of changes to the blood vessels that supply the skin. Dermopathy appears as a shiny round or oval lesion of thin skin over the front lower parts of the lower legs.Necrobiosis LipoidicaDiabeticorum : Another disease that may be caused by changes in the blood vessels is necrobiosis lipoidica diabeticorum (NLD). NLD causes spots similar to diabetic dermopathy, but they are fewer, larger, and deeperDisseminated granuloma annulare. This causes red, red-brown, or skin-colored raised rings or arcs on the skin. It usually occurs on the fingers, ears, or lower legs

Digital sclerosis. About one-third of people with type 1 diabetes have this condition, which can make the skin on the back of the hands become thick, waxy, and tight

Acanthosis nigricans. With this condition, the skin on the neck, armpits, or groin thickens and becomes brown or tan

Eruptive xanthomatosis. Young men with type 1 diabetes who also have high levels of cholesterol and fat in the blood often develop this conditionVitiligo: Vitiligo, a skin problem more commonly associated with type 1 diabetes than type 2 diabetes, affects skin coloration

Diabetes and Skin Infections
Bacterial skin infections are pretty common with diabetes such as : boil , folliculitis , or infection of the nail bed, Styes

Fungal infections are pretty common too, according to Hatipoglu. People with diabetes are likely to develop fungal infections in areas that get hot and sweaty, including:

Under the breasts

Between fingers and toes

In the armpits

In the groin area

men genital area

Keeping your diabetes under control is the most important factor in preventing these skin problems

السبت، 1 يناير، 2011

The disease, is not a fungal infection but rather a type of non-Hodgkin's lymphoma. It was so named because Alibert ( who first described mycosis fungoides in 1806 ) described the skin tumors of a severe case as having a mushroom-like appearance

The cause of mycosis fungoides is unknown .It is rare for the disease to appear before age 20, and it appears to be noticeably more common in males than females, especially over the age of 50 . The average age of onset is between 45 and 55 years of age for patients with patch and plaque disease only, but is over for patients who present with tumours, erythroderma (red skin) or a leukemic form (the Sézary syndrome).

Typical visible symptoms include rash like patches, tumors, or lesions. Itching is common, perhaps in 20% of patients, and is not universal.

Diagnosis is sometimes difficult because the early phases of the disease often resemble eczema or even psoriasis.

If treatment is successful the disease can go into a non-progressing state with clinically clear examination and various tests .Common treatments include simple sunlight, ultraviolet light, topical steroids, topical and systemic chemotherapies, local superficial radiotherapy, the histone deacetylase inhibitor vorinostat, total skin electron beam radiation, photopheresis and systemic therapies (e.g. interferons, retinoids, rexinoids) or biological therapies. Treatments are often used in combination

Encourage the use of supportive treatments in patients with mycosis fungoides to decrease pruritus and to lubricate the skin. Nonspecific antipruritic treatments used to control symptoms are useful and often necessary adjuncts to more specific therapies. Patients should avoid sun exposure and remain in a cool environment.

الأحد، 7 نوفمبر، 2010

Of all the news coming from the beauty community, the loudest buzz may be about the power of vitamins, minerals, and other nutrients to give skin a more radiant, healthy, and, yes, youthful glow.

"Your skin is the fingerprint of what is going on inside your body, and all skin conditions, from psoriasis to acne to aging, are the manifestations of your body's internal needs, including its nutritional needs .

Topical Vitamin C can prevent the consequences of prolonged sun exposure which can lead to skin cancer ,people who take vitamins C and E in the long term reduced their sunburns from exposure to UVB radiation

Vitamin A:

Topical vitamin A is the form that makes a real difference in your skin. Medical studies show a reduction in lines and wrinkles, good acne control, and some psoriasis relief, all from using creams containing this nutrient

Vitamin B Complex:

Without adequate amounts, you may end up with dermatitis (an itchy, scaly skin reaction) or sometimes even hair loss. Even a mild deficiency causes symptoms. topical form of vitamin B was shown to dramatically improve aging in human skin

Vitamin K:

showed that topical vitamin K works well to reduce circles under the eye as well as bruises

Selenium:

A number of scientists believe this mineral plays a key role in skin cancer prevention , selenium could help reduce your chance of burning

Copper:

Still another important mineral is copper. Together with vitamin C and the mineral zinc, copper helps to develop elastin, the fibers that support skin structure from underneath . improvements in skin roughness, clarity, fine lines, wrinkling, and overall photodamage

Zinc:

The third skin-friendly mineral is zinc, important if you have acne. In fact, sometimes acne itself is a symptom of a zinc deficiency