John Dudley's take: The Saints already have a playoff win in a hostile venue under their belts, which could make things a little easier today at CenturyLink Field. A little. As great as Drew Brees is, it's hard to imagine drastic improvement from the 34-7 whipping he took in a Week 13 loss at Seattle, when the Saints managed only 12 first downs and 188 total yards, and Russell Wilson threw for 310 yards with three TDs and no interceptions against Rob Ryan's defense.

John Dudley's pick: Seahawks 24-16

Indianapolis Colts (12-5) at New England Patriots (12-4)

8:15 p.m.

Dudley's take: The last time these teams met, the Patriots bludgeoned the Colts 59-24 in Foxborough. But that came in Andrew Luck's 10th NFL start, and Tom Brady was completing passes to Rob Gronkowski and Wes Welker with Vince Wilfork stuffing the "A" gaps (remember the good old days, Pats fans?). We should know by now to expect pretty much anything tonight, but it's tough to pick against Luck after the way he rallied Indy last week.