New Orleans police believe the shooter had been aiming for 33-year-old Terrence McBride, who has a previous conviction for heroin possession and pending drug and weapons charges.

A neighbor in the 5400 block of Burgundy Street, 16-year-old Jasmine Anderson, also died as a result of the shooting.

A 37-year-old woman was also injured in the shooting, which took place around 8 p.m.

Witnesses said that someone inside a dark gray Honda opened fire even though children were present and playing in the front yard and on the porch. A woman who was on the porch at the time of the shooting said two other children ages 5 and 11 were also outside playing at the time and escaped without injury.

"This was another unspeakable crime on the streets of New Orleans," Landrieu said at a news conference outside the NOPD's 5th District headquarters in the 9th Ward. "The relentless drumbeat of death will not stop until we as a community demand that it stops."

NOPD Superintendent Ronal Serpas said authorities have developed leads and a possible identity of a person who was in the car with the gunman.

Alanna Romain and her five children had been back in New Orleans not even a year after living in Texas, her father said.

"When she was living in Texas, I asked her not to come back here because of the violence," he said. "She wanted to be home -- wanted to be close to family. I wish they would have stayed in Texas."