A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA; Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, California 94305, USA Neuroscience Graduate Program, Stanford University School of Medicine, Stanford, California 94305, USA; Center for Tissue Regeneration, Repair and Restoration, V.A. Palo Alto Healthcare System, Palo Alto, California 94304, USA shows that “Human umbilical cord plasma proteins revitalize hippocampal function in aged mice.” This research paper was published, in the 19 April 2017 issue of the journal “Nature” [One of the best research journals in General sciences with an I.F of 43+], by Prof.Tony Wyss-Coray, Joseph M. Castellano and others.

This study suggests, for the first time, an amino acid-based therapy for age-associated decline in memory function in hippocampus.

Taurine, by increasing the expression of its target genes, may increase the levels of TIMP2. Thereby, it may: (1) increase cognition and learning; (2) improve spatial memory; and (3) promote hippocampal function (fig.1).

Figure1. Mechanistic insights into how Taurine, by increasing the expression of TIMP2, increases learning and memory in aged individuals.

Thus, pharmacological formulations encompassing “Taurine or its analogues either alone or in combination with other drugs“ may be used to suppress age-associated overall physiological decline of hippocampal function and improve cognition and memory.