Macro-Prep High Q Resin is a strong anion exchange resin containing quaternary amine functional groups that is ideal for purifying acidic and neutral proteins and peptides. It is an excellent choice for rapid purification and meets the demands of analytical, semipreparative, and process-scale applications.

This methacrylate copolymer bead provides high-resolution separations at very high flow rates. Changes in pH or ionic strength of the buffer do not cause shrinking or swelling of the support. The superior mechanical and chemical stability of Macro-Prep High Q Resin make it a preferred choice over other Q supports on the market. Macro-Prep High Q Resin can be sanitized with chaotropic agents and can be autoclaved. It provides consistent and reproducible results.

Regulatory support files are available upon request. Bio-Rad Laboratories is an ISO 9001-registered corporation.

Properties of Macro-Prep High Q Support

Type of support

Strong anion exchanger

Functional group

–N+(CH3)3

Typical dynamic binding capacity

≥37 BSA/ml

Nominal particle size

50 µm

Nominal pore diameter

1,000 Å

Recommended maximum linear flow rate

3,000 cm/hr

pH stability

1–10

Regeneration

in 1–2 M NaCl/KCl or 70% ethanol

Chemical Compatibility of Macro-Prep High Q Support

1% SDS

Yes

8 M guanidine-HCI

Yes

1 N HCI

Yes

100% ethanol

Yes

What is the education discount policy?

For more than 15 years, Bio-Rad has made science education a major priority. To support this effort, the company has implemented a discount policy that allows high school and college teaching laboratories to purchase kits, instruments, reagents, and other equipment at preferred prices.

How do I apply for the education discount?

If you are an educator at the high school or college level, visit our Education Discount Policy page to establish an education account number.

If you are placing an order, you may proceed with your order; the account price will be applied if it is lower than the list price. If the problem persists, please call customer service at
or send an email to