NeuropeptidesNeuropeptides transform skin showing signs of advanced aging such as deep lines, wrinkles and crepiness. Elasticity and firmness are restored while aging skin is rapidly revived and infused with nourishing hydration.

Olive PolyphenolsDr. Perricone's blend of antioxidants derived from the olive fruit and olive leaf deeply nourish even the most sensitive skin while delivering visible anti-aging results.

TocotrienolsTocotrienols are a potent form of Vitamin E considered 40 to 50 times more powerful than conventional forms. These antioxidants offer powerful protection against free radical and environmental damage, as well as unparalleled healing and nourishing benefits for red, irritated or dry skin.

Dr. Perricone recommends applying on cleansed skin to entire face making sure to bring up to the hairline and behind the ear. Use morning and evening for optimal results.

We do not recommend using any treatments for the face around the eyes. We suggest using an eye treatment as these are specifically formulated for this sensitive area.

Answered on 1/8/2015 by Anonymous

Q:

Is this serum discontinued, being reformulated, or just out of stock? If it's being reformulated, when will the new version be available and how will it differ? If it's discontinued, what serum do you now recommend for sensitive skin?

I bought all the hypoallergenic lyne , but , after the cleanser i dont know if i should apply de peptide complex with dry skin or a little bit wet...and How much of the peptide should I be applying to my face each time I put it on?

The Hypoallergenic Peptide Complex is a treatment and it is recommended to use a moisturizer over the top of it.

Answered on 7/26/2014 by Perricone MD Customer Care from 1-888-823-7837

Q:

I use cold plasma and sub-d in the am.with face firming activator,nd face finishing moisturizer. At night Concentrate restorative. my eyes are very sensitive and would like to start hypo allergenic. Also I am 74 and need to cut the budget. What do yousuggest that I change to that will be cheaper, since I am retired.

Interesting Inquiry – If you are looking for an eye cream for sensitive eyes , I would recommend our Hypoallergenic Firming Eye Cream, it addresses fine lines, los of firmness, crow’s feet, dark circles, all while hydrating the skin. If you are looking for just a facial cream , I would recommend the Hypoallergenic Peptide Complex Cream, it improve skin’s resilience, tone, and texture while minimizing fine lines and wrinkles. To help you maintain these amazing products on a budget, I would strongly recommend adding these products to our auto –replenishment program ! You control how often you receive products and also receive 10% off each product !

Answered on 7/23/2014 by Anonymous

Q:

I currently use blue plasma in the morning before face finishing moisturizer and vitamin c ester at night followed by face finishing moisturizer, so where would this product fit into that order of application?

The Hypoallergenic Peptide Complex would be used in the AM after the Blue Plasma and before the Face Finishing Moisturizer.

Answered on 5/18/2014 by Perricone MD Customer Care

Q:

I am 73 years and very sensitive skin, some eczema. What is the best product for my skin. What other products besides the "hypoallergenic peptide complex" should I use along with this complex for my daily regimenI love the photo plasma.

Dr. Perricone’s products have not been tested on women who are pregnant or nursing. Although Dr. Perricone does not foresee any problems with this, it is important that you know that they have not been tested. If you have any concerns about product usage, we recommend that you discuss this with your physician. We do list our ingredients on our product packaging and on our website, so we recommend checking these ingredients with your personal physician.

I'm experiencing a significant amount of redness and have for some time, my entire face is red/orange and darker than my neck. I currently use Cold Plasma (along with several other Perricone MD products); would / could this replace Cold Plasma or must it be used in addition to it? I like the results I've received from Cold Plasma but if I can switch a few things I'm using to the sensitive line that address this redness without losing Cold Plasma's results, I'd like to.

The Hypoallergenic Peptide Complex would be used after applying the Cold Plasma twice per day. For additional benefits I would recommend using the Hypoallergenic Gentle Cleanser, the Hypoallergenic Firming Eye Cream and the Hypoallergenic Nourishing Moisturizer.

I haven't noticed any dramatic results with this product, but I will say that it feels really nice. I used to apply a thin layer of this underneath the nourishing moisturizer and it definitely left a comforted supple feel to my skin. Then I started mixing it with the moisturizer and applying it that way- I noticed no difference in the feel of the product, but it was a much quicker way to apply the treatment. I prefer this method and am wondering what Perricone advises.

Anyhow, since I have used this product I have noticed that my skin feel more supple and hydrated. I have little irritation and my skin tone seems more even- less incidences of red blotchiness that I tend to get from product sensitivity. I haven't noticed a difference in my fine lines and I don't have wrinkles yet, so I can't report on that.

After purchasing High Potency Night repair which I found too strong for my skin this came as a welcome alternative. After using predominantly at night I have noticed a more refined skin, smoothed. My skin loves it, I just wish they would make it in a larger bottle!