Mario Artist: Paint Studio is a Japan-only game released on December 1, 1999 for the failed Nintendo 64DD, as part of the Mario Artist series. It was one of the only games released for the system and was never popularized as a result.

Mario Artist: Paint Studio worked like the earlier title, Mario Paint, in that players used different paint tools to draw images. Frequently bundled with the Paint Studio was the Nintendo 64 Mouse controller, which made painting on the game similar to painting on a computer. The player can play a slideshow of their images with music. Pictures of famous Nintendo characters could be used and manipulated on screen, and additional images could be imported from video tape or a Game Boy Camera using the Nintendo 64 Capture Cartridge. It is possible to create short animations with this game, 35 frames long. There are also minigames, including Fly Swatting (ovbiously based on the Mario Paint favorite Gnat Attack). The player can explore three 3D worlds-Mars, Underwater and Dinosaur Land (not to be confused with Dinosaur World) The player can travel through these environments and take pictures of the creatures who inhabit it. This feature is said to be similar to Pokémon Snap.