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ZytoDot ® 2C SPEC EML4 Break Apart Probe

The ZytoDot ® 2C SPEC EML4 Break Apart Probe is designed to detect rearrangements involving the chromosomal region 2p21 harboring the EML4 gene. Inversions in the short arm of chromosome 2 [inv(2)(p21p23)] have been detected frequently in NSCLC and lead to the formation of EML4-ALK fusion transcripts.

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