(CNN) – Nancy-Ann DeParle, among the most prominent women in President Barack Obama’s inner circle, is set to depart her White House post after his second-term inauguration.

DeParle, deputy White House chief of staff, will join the Brookings Institution later this month and also begin lecturing at Harvard Law School. News of DeParle’s departure was announced Friday by Brookings Institution’s president, Strobe Talbott.

Earlier this week, Labor Secretary Hilda Solis announced she would resign. EPA Administrator Lisa Jackson and Secretary of State Hillary Clinton also are on their way out.FULL POST

President Obama turns his focus to foreign policy with a visit from Afghan President Hamdi Karzai to wrap up the busy week at the White House. After a bilateral meeting in the morning, the two leaders will have a working lunch followed by a joint press conference. The White House warns us not to expect any firm agreement on troop numbers to come out of today's meeting, but the two leaders will discuss the nature of the U.S. presence in Afghanistan after combat troops leave in 2014. Additionally, the U.S. and Afghanistan are in the middle of negotiating a bilateral security agreement which the White House hopes to make progress on during today's visit.

Meanwhile, Vice President Biden continues his work this week with the gun control working group by holding another meeting this afternoon with representatives of the video game industry. Attorney General Eric Holder and HHS Secretary Kathleen Sebelius will join him during the meeting. Vice President Biden said he'll be sending his group's recommendations to the president's desk next week sometime.

Click below for the full schedule, as released by the White House. FULL POST

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OTR

Category: Thing

Some presidential movements are OTR, or off-the-record, to the public and press until the president's motorcade arrives at the previously undisclosed location.