Protein Summary

The genomic region NP_828850.1 from Sars coronavirus translates into the Nsp3e domain of the non-structural protein (Nsp) 3. Nsp3 is the largest SARS nonstructural proteins. It is predicted to have multiple functional domains [Ref].

The 2k87 structure corresponds to residues 1066–1181 within the functional domain nsp3e. The SCOP fold type assignment suggests that Nsp3e is a catalytic domain which belongs to the family of DNA ligase/mRNA capping enzyme, and adopts an ATP-grasp fold type (SCOP56058).