Rochester, New York – Last week, Vice President Biden announced that the Research Foundation for the State University of New York (RF SUNY) will lead a new Manufacturing Innovation Institute to secure U.S. leadership in manufacturing integrated photonics. These emerging technologies have the potential to transform many industries – from creating “needleless” tests for medical conditions like diabetes, to increasing the carrying capacity of broadband communications ten times over.

The Manufacturing Innovation Institute for Integrated Photonics is the sixth of nine such public-private partnerships to boost advanced manufacturing, foster American innovation, and attract and create jobs that strengthen the middle class. After a decade of decline in the 2000s, when 40% of all large factories closed their doors, American manufacturing is adding jobs at its fastest rate in decades, with nearly 900,000 new manufacturing jobs created since February 2010. Manufacturing production is up by almost a third since the recession and the number of factories across the United States is growing for the first time since the 1990s. Today’s new action is the kind of investment we need to build on this progress, creating the foundation for American manufacturing leadership for years to come.

The Department of Defense is awarding the new Manufacturing Innovation Institute for Integrated Photonics to a consortium of 124 companies, nonprofits, and universities led by RF SUNY. With a total investment of over $610 million – $110 million in federal funds, and more than $500 million in non-federal contributions – the announcement marks the largest public-private commitment to date for a manufacturing institute launched in the United States.

Headquartered in Rochester, New York, the long-time home of optical technology pioneer Eastman Kodak, the new Department of Defense led manufacturing institute will help spark new growth in manufacturing building on the area’s legacy of leading optical and photonics technology capabilities – and position the United States for continued leadership in this critical technology area. Already, member companies are demonstrating what is possible atop such foundations - including Harris Corporation, Sydor Optics, and Optimax, which have all recently opened or expanded operations in the region, bringing dynamism to the region’s intrepid photonics cluster. By attracting hundreds of millions of dollars of new investment in photonics, and convening leading photonics capabilities from across the nation in Rochester, the institute will accelerate the growth of this industry in the upstate New York area.

The new photonics institute is the sixth of nine announced as part of the National Network of Manufacturing Institutes (NNMI). From the very first manufacturing institute, pioneering novel 3D printing technologies in Youngstown, Ohio, to the most recently awarded institute pushing the boundaries on advanced materials in Knoxville, Tennessee – each institute is part of a growing network dedicated to securing U.S. leadership in the emerging technologies required to win the next generation of advanced manufacturing.

Bridging the gap between applied research and product development, each institute brings together companies, universities, other academic and training institutions, and Federal agencies to co-invest in key emerging technology areas that can encourage investment and production in the U.S. This latest institute, a new public private partnership led by RF SUNY, will bridge advanced research and commercial product development, yielding critical defense and telecommunications advances – while also investing in education and workforce development to train and position the next generation of manufacturers in integrated photonics.

Just as integrated electronic circuits allowed for advanced processing in computers and cellphones, integrated photonic components can pack even more processing power into a single chip, creating new possibilities for computing and telecommunications. An emerging technology for carrying light-waves, integrated photonics has the potential to revolutionize entire industries—from increasing the carrying capacity of broadband communications ten-fold, to creating needle-free tests for common conditions like diabetes, and to improving imaging capabilities in defense operations.

Vice President Biden is also calling on Congress to make a clear choice: We can make critical bipartisan investments to strengthen manufacturing across the United States, laying a strong foundation for good jobs and economic growth – or we can pull back, letting other countries and their workers take the lead. The President’s Fiscal Year 2016 Budget would strengthen America’s leadership in advanced manufacturing, providing the resources to grow the NNMI to 16 institutes by the end of 2016 (with a goal of up to 45 institutes over a decade). In contrast, the House and Senate funding bills would entrench harmful "sequester" levels of funding, putting critical investments in advanced manufacturing, workforce development and training, and innovation at risk.

Background on the Integrated Photonics Institute for Manufacturing Innovation Institute:

The new institute the Department of Defense is awarding today will focus on cutting-edge research in integrated photonics – using multiple units of light, on a single platform, to improve the performance and reliability of telecommunications, radar, lasers, and other technologies.

Photonics is the science of using and controlling photons – the smallest unit of light – to convey information and images. By shrinking electronic components like lasers and optical sensors to a scale hundreds of times smaller than a single living cell – and putting these components on a single platform – integrated photonics could advance technology in ways never before possible, including by:

Revolutionizing long-haul telecommunications, enabling much more resilient fiber with much greater bandwidth

Creating dramatic energy savings at high-performing data centers, which across the country now consume almost as much power each year as the entire state of New York.

Improving security operations, with applications in radar, electronic warfare, imaging, sensing, and communication systems used across the entire spectrum of land, air, sea, and space-based platforms.

Integrated photonics is a type of microelectronics, a set of technologies that has powered decades of American economic growth. Investing in scalable photonics manufacturing is critical to meeting our technology and economic needs in the decades ahead. The market for integrated photonics is growing rapidly. But many manufacturers – especially small businesses – have inadequate capital to penetrate it. The new institute will focus on bringing these technologies down the cost curve, letting American companies lead in their development.

The Integrated Photonics Institute for Manufacturing Innovation will work to develop lower-cost, higher-speed, and more efficient manufacturing processes for photonic circuits, by:

Creating a standardized platform currently lacking in the integrated photonics space, making it easier to scale the technology across multiple markets and drive performance, cost, and scaling requirements.

Assembling a world-class team of organizations from across the photonics industry, including leading manufacturers, material suppliers and software developers, government and academia.

Pairing photonics companies (like Analog Photonics, Juniper Networks, and OptiPro) with key end users of integrated circuits (like Northrop Grumman for defense imagery and Hewlett Packard for high performance computing) and top research universities (like the University of Rochester, with its pioneering integrated circuitry labs, and the California Institute of Technology, with advanced lithography testing).

The winning team, led by the Research Foundation of the State University of New York (RF SUNY) and headquartered in Rochester, NY, includes the following 75 key partners and 49 additional consortia members:

20 Universities and Laboratories: Boston University, California Institute of Technology, Columbia University, Massachusetts Institute of Technology, Rochester Institute of Technology, Stanford University, State University of New York, University of Arizona, University of California Berkeley, University of California Davis, University of California San Diego, University of California Santa Barbra, University of Colorado-Boulder, University of Delaware, University of Rochester, University of Virginia, Alfred University, Binghamton University, Drexel University, and Pennsylvania State University.

33 Community Colleges and Other Schools: NEW YORK: Adirondack Community College, Broome Community College, Cayuga Community College, Clinton Community College, Columbia-Greene Community College, Corning Community College, Dutchess Community College, Erie Community College, Fashion Institute of Technology, Finger Lakes Community College, Fulton-Montgomery Community College, Genesee Community College, Herkimer County Community College, Hudson Valley Community College, Jamestown Community College, Jefferson Community College, Mohawk Valley Community College, Monroe Community College, Nassau Community College, Niagara County Community College, North Country Community College, Onondaga Community College, Orange County Community College, Rockland Community College, Schenectady County Community College, Suffolk County Community College, Sullivan County Community College, Tompkins Cortland Community College, Ulster County Community College, Westchester Community College. CALIFORNIA: Allan Hancock Community College, Santa Barbara Community College, and Ventura College. MASSACHUSETTS: Quinsigamond Community College.

Columbus, Ohio – Automatic Identification Systems (AIS) officials have announced expansion of its SCANALYST 3 family to include DPM (direct parts marking). DPM is a key marking technology that uses laser or peening to create a permanent 2D barcode right on the part. There is no label or package required with DPM and the mark is useful through the life of the product. The identifying mark is actually part of the product. These features make it the method of choice for healthcare, defense, and manufacturing identification and traceability requirements.

"These applications require 'Doing it right.' The cost of a mistake could be very high so the risk must be minimized. That is why the FDA and DOD have set minimum acceptable quality levels for their programs."

Aside from the risk of use, there is the risk of destroying your product. Imagine building a great product only to have it ruined by marking it incorrectly. You do not have to do that. SCANALYST 3 uses predictive analysis methods to give you the assurance that your process is under control and that the barcode can be read by all.

There are many new features that were added specifically for DPM. New algorithms, lighting, and program flow were just a few. SCANALYST 3 has already been recognized as an easy to use and complete tool for barcode users. The system is portable so it can be taken to the product line. The system is able to inspect irregular surfaces. It is highly graphical, which makes it easy to collaborate with suppliers and clients and solve problems fast. The system also has an on-board database, which is useful to those needing to certify their inspection results or working to develop best practices. SCANALYST 3 DPM also has all of the core capabilities to inspect paper labels and packaging materials, making it the only truly 'Universal' barcode inspection tool available.

Those who currently print barcodes know that it is important to their company's bottom line and to its customers. Each product's barcode must withstand scrutiny and be in compliance with industry standards. Compliance is a complex task that requires the right tools. SCANALYST 3 is designed to meet these needs. This comes just in time for companies that are implementing complex standards such as UDI in healthcare, GS1 standards, ANSI/ISO quality grading, UID in manufacturing, complex 2D GS1 Coupon codes or just trying to measure and improve their existing applications and production.

Tampa, Florida – For many medical institutions and universities, commercializing patented innovations developed by their researchers, physicians, and other inventors can be a constant challenge. Taking an idea all the way to market is difficult, and successes are rare.

A new company in Tampa wants to change that.

Medical Device Investments (MDI) was created to commercialize medical devices and technology licensed from universities, hospitals, and physicians. MDI develops, manufactures, and markets the products, with the intent of selling them to major manufacturers for distribution to hospitals, surgery centers, and doctors' offices worldwide.

"We wanted to create a business in which new devices are constantly being identified, developed and brought to market,'' said chief executive officer Doug Martin. "Too many worthwhile products end up sitting on a shelf collecting dust.''

MDI focuses on products designed to improve patient care and reduce hospital acquired complications, such as infections, which result in lower hospital profits. Many of MDI's licensed technologies are patented improvements on commonly used products.

Martin, a board member for the Tampa Bay Innovation Center, founded the company with Allen Craig, Scott Hampton, and Matthew Miller. MDI added Matthew Otten to lead the company's subsidiary, MDI Engineering, which supplies design, engineering and prototyping services to MDI as well as external device industry clients.

Since incorporating in September, MDI has obtained the licensing rights to six devices invented at Moffitt Cancer Center in Tampa, including five by anesthesiologist Dr. Tariq Chaudhry, and two interventional cardiology catheters by cardiologist Dr. Hitinder Gurm at the University of Michigan.

MDI's initial portfolio of products includes the Safe Clip, which is used with intravenous catheters to prevent blood loss, and the Brachytherapy Safe Catheter, which is used with High Dose-Rate (HDR) brachytherapy to block cancer-fighting radioactive pellets from damaging healthy organs. All of MDI's products are in various stages of development, with the Safe Clip the closest to manufacturing and distribution, most likely in the next year. Once the company reaches 12 products under concurrent development, MDI plans an initial public offering.

MDI differs from other startup device companies in that it works with multiple products simultaneously to spread overhead costs and reduce risk, rather than concentrate on one product that may take years and millions of dollars to develop. Having products at different points in the development process ensures a more steady revenue stream for investing in new technologies and eliminates wasted resources involved in waiting for a product to reach its next milestone.

"No one in the industry is taking this approach,'' Martin said. "We want to become a self-sustaining engine for developing products that benefit from economies of scale. Our vision is to become a Center of Excellence for the commercialization of innovative medical technologies.''

Washington, D.C. – Five men with complete motor paralysis were able to voluntarily generate step-like movements thanks to a new strategy that non-invasively delivers electrical stimulation to their spinal cords, according to a new study funded in part by the National Institutes of Health. The strategy, called transcutaneous stimulation, delivers electrical current to the spinal cord by way of electrodes strategically placed on the skin of the lower back. This expands to nine the number of completely paralyzed individuals who have achieved voluntary movement while receiving spinal stimulation, though this is the first time the stimulation was delivered non-invasively. Previously it was delivered via an electrical stimulation device surgically implanted on the spinal cord.

In the study, the men’s movements occurred while their legs were suspended in braces that hung from the ceiling, allowing them to move freely without resistance from gravity. Movement in this environment is not comparable to walking; nevertheless, the results signal significant progress towards the eventual goal of developing a therapy for a wide range of individuals with spinal cord injury.

“These encouraging results provide continued evidence that spinal cord injury may no longer mean a life-long sentence of paralysis and support the need for more research,” said Roderic Pettigrew, Ph.D., M.D., director of the National Institute of Biomedical Imaging and Bioengineering at NIH. “The potential to offer a life-changing therapy to patients without requiring surgery would be a major advance; it could greatly expand the number of individuals who might benefit from spinal stimulation. It’s a wonderful example of the power that comes from combining advances in basic biological research with technological innovation.”

The study was conducted by a team of researchers at the University of California, Los Angeles; University of California, San Francisco; and the Pavlov Institute, St. Petersburg, Russia. The team was led by V. Reggie Edgerton, Ph.D., a distinguished professor of integrative biology and physiology at UCLA and Yury Gerasimenko, Ph.D., director of the laboratory of movement physiology at Pavlov Institute and a researcher in UCLA’s Department of Integrative Biology and Physiology. They reported their results in the Journal of Neurotrauma.

In a study published a little over a year ago, Edgerton – along with Susan Harkema, Ph.D., and Claudia Angeli, Ph.D., from the University of Louisville, Kentucky – reported that four men with complete motor paralysis were able to generate some voluntary movements while receiving electrical stimulation to their spinal cords. The stimulation came from a device called an epidural stimulator that was surgically implanted on the surface of the men’s spinal cords. On the heels of that success, Edgerton and colleagues began developing a strategy for delivering stimulation to the spinal cord non-invasively, believing it could greatly expand the number of paralyzed individuals who could potentially benefit from spinal stimulation.

“There are a lot of individuals with spinal cord injury that have already gone through many surgeries and some of them might not be up to or capable of going through another,” said Edgerton. “The other potentially high impact is that this intervention could be close to one-tenth the cost of an implanted stimulator.”

During this most recent study, five men – each paralyzed for more than two years – underwent a series of 45-minute sessions, once a week, for approximately 18 weeks, to determine the effects of non-invasive electrical stimulation on their ability to move their legs.

In addition to stimulation, the men received several minutes of conditioning each session, during which their legs were moved manually for them in a step-like pattern. The goal of the conditioning was to assess whether physical training combined with electrical stimulation could enhance efforts to move voluntarily. For the final four weeks of the study, the men were given the pharmacological drug buspirone, which mimics the action of serotonin and has been shown to induce locomotion in mice with spinal cord injuries. While receiving the stimulation, the men were instructed at different points to either try to move their legs or to remain passive.

At the initiation of the study, the men’s legs only moved when the stimulation was strong enough to generate involuntary step-like movements. However, when the men attempted to move their legs further while receiving stimulation, their range of movement significantly increased. After just four weeks of receiving stimulation and physical training, the men were able to double their range of motion when voluntarily moving their legs while receiving stimulation. The researchers suggest that this change was due to the ability of electrical stimulation to reawaken dormant connections that may exist between the brain and the spinal cord of patients with complete motor paralysis.

Surprisingly, by the end of the study, and following the addition of buspirone, the men were able to move their legs with no stimulation at all and their range of movement was – on average – the same as when they were moving while receiving stimulation.

“It’s as if we’ve reawakened some networks so that once the individuals learned how to use those networks, they become less dependent and even independent of the stimulation,” said Edgerton.

The researchers also made extensive recordings of electrical signals generated in the calf muscle and the muscle directly below the calf while the men attempted to flex their feet during stimulation. Over time, these signals increased with the same amount of stimulation, further supporting the hypothesis of re-established communication between the brain and spinal cord.

Edgerton has already initiated a new study to see whether these same men can be trained with non-invasive spinal stimulation to fully bear their weight, a feat that the four men with surgically implanted stimulators have already achieved. In addition, he is interested in determining whether, similar to epidural stimulation, non-invasive stimulation can help individuals regain some autonomic functions lost due to paralysis such as the ability to sweat, regulate blood pressure, and control bladder, bowel, and sexual function.

The hope is that further research can help determine whether non-invasive stimulation can restore function that will truly impact patient lives.

Edgerton also wants to test non-invasive stimulation on individuals who have partial paralysis. “We have focused on individuals with complete paralysis throughout this whole process because we knew that was going to be the toughest patient population to see changes in. We’ve always thought, and we have every reason to believe, that those individuals with partial injuries have even more room for improvement,” said Edgerton.

Though a non-invasive stimulation could offer advantages over a surgically implanted device, Edgerton says both need to continue to be developed. For example, a non-invasive stimulator might be useful in determining whether a patient will be receptive to neuromodulation, which could then help determine whether undergoing surgery to implant a stimulator is warranted. Alternatively, Edgerton speculates it may be possible early after an injury for non-invasive stimulation to help patients achieve a certain level of motor control that then allows them to continue to improve with physical rehabilitation and avoid surgery altogether.

“All patients are going to need something slightly different, and maybe non-invasive stimulation is going to be best in some cases and epidural stimulation in others,” said Edgerton. “What we need to do is maximize the clinical tool box that we have so that the physician and the patient can select a therapy that is best for them.”

This research was supported in part by the National Institute of Biomedical Imaging and Bioengineering, the National Institute of Neurological Disorders and Stroke and the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and the National Center for Advancing Translational Sciences at NIH under award numbers EB015521, EB007615, and TR000124, the Christopher and Dana Reeve Foundation, the Walkabout Foundation, and the F. M. Kirby Foundation, the Russian Foundation for Basic Research grant ?13-04-12030, the Russian Scientific Fund project ? 14-45-00024, the J. Yang and Family Foundation, and the Paul and Daisy Soros New American Fellowship.

The mission of the National Institute of Biomedical Imaging and Bioengineering is to improve health by leading the development and accelerating the application of biomedical technologies. The Institute is committed to integrating the physical and engineering sciences with the life sciences to advance basic research and medical care. NIBIB supports emerging technology research and development within its internal laboratories and through grants, collaborations, and training. More information is available at the NIBIB website: http://www.nibib.nih.gov.

The NINDS is the nation’s leading funder of research on the brain and nervous system. The mission of NINDS is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease.

About the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD): The NICHD sponsors research on development, before and after birth; maternal, child, and family health; reproductive biology and population issues; and medical rehabilitation. For more information, visit the Institute’s website at http://www.nichd.nih.gov/.

The National Center for Advancing Translational Sciences (NCATS) is a distinctly different entity in the research ecosystem. Rather than targeting a particular disease or fundamental science, NCATS focuses on what is common across diseases and the translational process. The Center emphasizes innovation and deliverables, relying on the power of data and new technologies to develop, demonstrate and disseminate improvements in translational science that bring about tangible improvements in human health. More information: http://www.ncats.nih.gov.

About the National Institutes of Health (NIH): NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit www.nih.gov.

NIH...Turning Discovery Into Health

Source: NIH

BIG Kaiser Precision Tooling’s benchtop presetter

As an upgraded model of the popular DIASET, the benchtop tool presetter is now available with camera and LCD touchscreen.

The DIASET is built with a stable measuring column and base made out of mineral cast. This strong foundation ensures extreme rigidity and excellent temperature resistance for high repeatability and positioning accuracy of 0.0001". These impressive capabilities on an entry-level presetter are also supported by horizontal and vertical slides that smoothly move along hardened and precision ground guideways, both with pneumatic locking mechanisms and foot pedal control.

The high-precision rotating spindle allows a guaranteed accuracy of runout measurements to less than 0.0008" T.I.R. and is available with either integral ISO50 or ISO40 taper spindles. Reduction adapters are available for other common interfaces (ISO, HSK, KM, Polygon, etc.). Many combinations of max diameter/max length are available to perfectly suit your measuring needs – and budget.

Additionally, two built-in USB ports for simultaneous external data saving and label printer connection, as well as internal storage of up to 99 reference points, means investing in the DIASET Camera Type will dramatically reduce the chance of human error in tool preparation.

Leasing options are available and price quotes can be easily requested on the BIG Kaiser website.