Kombiglyze XR Drug Interactions

Related Multimedia

Click on an icon to view.

Interested in a Discount on Kombiglyze XR?

Our free DiscountRx savings card can help you and your family save money on your prescriptions. This card is accepted at all major chain pharmacies, nationwide. Enter your name and email address to receive your free savings card.

Enter Your Name

Enter Your Email Address

Our free DiscountRx savings card can help you and your family save money on your prescriptions. This card is accepted at all major chain pharmacies, nationwide. Enter your name and email address to receive your free savings card.

Kombiglyze XR Drug Interactions Explained

The following sections explain in detail the potentially serious interactions that can occur when Kombiglyze XR is combined with any of the drugs listed above.

Calcium Channel Blockers

Taking Kombiglyze XR with calcium channel blockers can make Kombiglyze XR less effective, increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your Kombiglyze XR dosage, especially when starting or stopping a calcium channel blocker.

However, taking Kombiglyze XR with nifedipine, which is a calcium channel blocker, can also increase the level of metformin (one of the components of Kombiglyze) in your blood. Your healthcare provider may need to adjust your dose of Kombiglyze XR to prevent this drug interaction.

Certain Antibiotics or Antifungals

Some antibiotics and antifungals may increase the level of Kombiglyze XR in the bloodstream. As a result, a lower Kombiglyze XR dosage (2.5 mg /1000 mg once daily) is usually recommended for people in such situations. Check with your healthcare provider before combining Kombiglyze XR with such antibiotics or antifungals.

Certain Decongestants

Taking Kombiglyze XR with certain decongestants can make Kombiglyze XR less effective, increasing your chance of high blood sugar (hyperglycemia). Decongestants are in many cough and cold products, so talk to your healthcare provider before taking any cough or cold products if you are taking Kombiglyze XR.

Certain Protease Inhibitors

Some protease inhibitors may increase the level of Kombiglyze XR in the bloodstream. In most cases, a lower dosage of Kombiglyze XR (2.5 mg/1000 mg daily) is recommended for use in combination with these protease inhibitors. Be sure to check with your healthcare provider before combining these drugs.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind.
Site users seeking medical advice about their specific situation should consult with their own physician. Click
Terms of Use for more information.

You've chosen to add topics from the topic group to your selected topics.

Are you sure you want to add all of these topics?

Are You Sure?

You've chosen to clear all of your selected topics. Remember, you need at least one selected topic to use HealthSavvy. If you choose this option, it cannot be undone, and you'll need to choose at least new topic to continue using your HealthSavvy programs.