The Yankees have home-field advantage throughout the American League playoffs, but the Twins might have the biggest single-game home-field edge.

Sources have told The Post that if the Cubs beat out the Astros to win the National League Central Division, Cubs vs. Braves will be the ESPN prime-time game Tuesday and Saturday. That means the Yankees-Twins will play day games in Game 1 at the Stadium and Game 3 in the Metrodome.

Playing a day game in the Metrodome can be a fielder’s nightmare. The white ball can disappear against the dome’s white roof. Many opposing players have gone into the Metrodome and had the embarrassing experience of not having the slightest idea where a fly ball has gone.

The Yankees have owned the Twins over the past two years. The Bombers are 7-0 against the Twins this season, including 4-0 in the Metrodome, where they played error-free ball.

The last time the Yankees and Twins faced each other was a 1:05 p.m. start in the Metrodome on April 21. The Yankees won that game 15-1. Last season, the Yankees were 6-0 against the Twins, 3-0 in the Metrodome. But the playoffs are a different breed of baseball.

The Yankees learned last season not to take any team lightly. The red-hot Angels, who had almost no playoff experience, blew away the Yankees in four games. So regardless of where or when the games are, the Yankees aren’t putting much stock in the fact that they’ve won 13 straight against the Twins.

“We don’t feel the 13-0 is anything more than making us the favorites,” Joe Torre said.

The Twins were terrific at home this season, with a 48-33 record. But the Yankees were more impressive on the road, going 51-29.