..Further pharmacokinetic studies to unveil potential Western and especially African herb-antiretroviral drug interactions are urgently required, and the clinical significance of these interactions should be assessed...

Therapeutic drug monitoring of antidepressants and cytochrome p450 genotyping in general practice

..An informative discontinuation letter for patients has been shown to reduce long-term benzodiazepine use in general practice. However, little is known about its wide scale implementation in primary care...

Comparison of two methods for performing treatment reviews by pharmacists and general practitioners for home-dwelling elderly people

..These studies prompted the initiation of a Dutch multidisciplinary task force, which was assigned to reduce the number of prescriber-related hospital admissions related to medications (HARMs) in a quick-win way...

..The objective of the study was to assess the association between the quality of drug prescribing based on three indicator types derived from the DU90% method and different levels of functioning in pharmacotherapy audit meetings (PTAMs)...

Treatment reviews of older people on polypharmacy in primary care: cluster controlled trial comparing two approaches

..Future studies should also assess whether results are sustained, the optimal time interval between reviews of repeat prescriptions, and the possibilities offered by new computerised support technologies...

Interventions to improve medication compliance in older patients living in the community: a systematic review of the literature

..Adequate dosing of medication in renal impairment to prevent hospitalizations and adverse reactions is a growing concern in the aging society. There are several dosing guidelines available, but structural use is uncommon...

Safety concerns about kava not unique

Peter A G M De SmetLancet 360:1336. 2002

Overanticoagulation associated with combined use of antibacterial drugs and acenocoumarol or phenprocoumon anticoagulants

..This raised the question, how often Dutch community pharmacists have personal consultations with their patients in daily practice, on which factors this depends, and what kind of topics are discussed during these meetings...

Overanticoagulation associated with combined use of lactulose and acenocoumarol or phenprocoumon

..Documentation of diseases and intolerabilities in electronic patient records (EPRs) in pharmacies is needed to produce an alert in case a contraindicated medicine is prescribed. Limited research is available concerning EPRs in pharmacies...