Clinical trial of the efficacy and safety of oral etretinate with calcipotriol cream compared with etretinate alone in moderate-severe psoriasis. Calcipotriol improves the response of psoriasis to PUVA. 58Turner, RJ, Walshaw, D, Diffey, BL, and Farr, PM. Calcitriol ointment has been approved for the treatment of psoriasis in many countries around the world. Speight and Farr, 1994; E.L. Speight, P.M. Farr. Calcipotriol improves the response of psoriasis to PUVA. Combination therapy to treat moderate to severe psoriasis. E.L., Farr, P.M. Calcipotriol improves the response of psoriasis to PUVA. 1994;130:7982.

In the laboratory, calcipotriene, also called calcipotriol outside the United States, effectively reduced proliferation and induced differentiation of keratinocytes. See also page 1305 With this background, calcipotriene therapy was introduced in the United States in 1994. Speight EL, Farr PM. Calcipotriol improves the response of psoriasis to PUVA. Overview of Farr P M research, his coauthors and publications. 1994. Speight E L, Farr P M 1994. Erythemal and therapeutic response of psoriasis to PUVA using high-dose UVA. Calcipotriol improves the response of psoriasis to PUVA. The introduction of PUVA for the treatment of generalized psoriasis was a major advance and afforded the availability of an outpatient therapy for patients with severe disease who had often previously required hospitalization. Gordon PM, Diffey BL, Matthews JN, Farr PM.

References In Dermatologic Clinics

Palmoplantar Psoriasis: Treatment with Calcipotriol and Local UVA Radiation Compared with Local PUVA. The most commonly used therapeutic options for palmoplantar psoriasis are long-term therapy with topical corticosteroids and local PUVA. A retrospectiveanalysis of treatment responses of palmoplantar psoriasisin 114 patients. Speight EL, Farr PM. Calcipotriol improves the responseof psoriasis to PUVA.