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This weapon is a .50 caliber bolt-action sniper rifle that is designed for use against military equipment (or "materiel" in military terminology). The AMR is similar in design principle to that of a sniper rifle, delivering a high power shot at long distances with great accuracy, although chambered in a larger caliber for hardened targets. As such, the AMR has extremely high damage and low spread and comes pre-equipped with a scope. The magnification level of the scope is 3.13x. Offsetting this is its slow rate of fire, resulting in a low damage-per-second and that the weapon itself weighs 20 pounds, making it one of the heaviest shoulder fired weapons in the game.

Additionally, its .50 MG ammunition is very rare, very expensive, and is heavy if carried in bulk in hardcore mode; a full magazine weighs two pounds without the Pack Rat perk, and one pound with the perk.

When fired from the hip (without aiming), the resulting recoil from the weapon's large caliber will result in the user being pushed slightly backwards (evident in third-person view). Aiming down the scope will prevent this.

NCR Veteran Rangers will usually carry these when the player reaches a medium-high level. The rifle will commonly be in poor condition when looted from them. NCR veteran rangers are common at Camp Golf.

pcps3xbox360 If loading a saved game from the main menu in which the anti-materiel rifle is equipped and drawn, the reload animation will take twice as long as normal. This can be solved by simply switching to another gun and then back again. [verified]

pcxbox360 When fired at close range, it may completely miss even though the end of the barrel is almost literally touching the target, this is more common when you are not aiming down the sights. [verified]

pc When the weapon is fired in short range (almost melee), the barrel sticks through the enemy and misses the target. [verified]

ps3xbox360 If an anti-materiel rifle loaded with incendiary rounds is used to target anyone in V.A.T.S and V.A.T.S is canceled without being activated, the targeted opponent will still catch fire, causing standard fire damage. [verified]

ps3 Sometimes when zoomed in the scope glitches and prevents sniping with the scope. Turning off the system and reloading the save file will fix this. [verified]