in your head – then you’ve got a neurodegenerative disease such as Alzheimer’s

Maybe you’re rethinking the “margarine” is a health food.

But its healthfulness depends on your genes.

PUFAs biochemistry directed by FADS cluster

Arachidonic acid belongs to a class of chemicals called polyunsaturated fatty acids (PUFAs). Organizations such as the American Heart Association encourage people to make PUFAs a significant part of their diet. But PUFA biochemistry is complicated.

To be a PUFA, a chemical must be a fatty acid – which means that it is a very long chain of carbon atoms with a carboxyl group stuck on the end.

But precisely how many carbons are in the chain and the types of bonds holding the carbons together, makes a big difference to how the chemical behaves. So PUFAs are not created equal. And what is created, depends on what you eat, as well as the activities of several enzymes.

Mother nature packaged many of the genes that code for these enzymes on a small region of chromosome 11, in an area nicknamed the FADS cluster.

The FADS cluster determines how efficient the whole process is.

FADS cluster is variable

Just like our colouring (skin, eyes, hair) and the shape of your ears and nose are variable, the FADS cluster is different in each of us.

Some people are very efficient at creating long chain PUFAs and some people are slow.

In the case of PUFAs, slow is actually better, because slow coaches don’t produce as much arachidonic acid. Less arachidonic acid means less bad eicosanoids (inflammatory messengers) and less inflammation. Less inflammation ultimately equals better health.

African ancestors put you at risk

Researchers looked at FADS clusters in different population groups within America.

They found something very interesting

White people (or those with European ancestors) are slow

Black people (or those with African ancestors) are fast

So your genes are impacting what happens when you eat a piece of cake or cookie baked using margarine.

If you’re white, you maybe all right, but if you’re black, you may be dialling up the stress levels.

Balance your eicosanoids

There is no one diet fits all – we are each a unique package of chemicals.

In the future, we will all be following personalized diet plans but until then, read the signs in your body and make the necessary adjustments.

Inflammatory diseases are a sign that the eicosanoids are out of balance.

Fortunately, fixing this problem is relatively easy. Restore the balance by boosting omega-3 levels to counterbalance the excess omega-6. And where possible, try to cut down on omega-6 consumption – so lay off the cookies and cakes.

Disclaimer : The stories and articles are provided as a service. Dr Sandy's opinions are for information only, and are not intended to diagnose or prescribe. For your specific diagnosis and treatment, consult your doctor or health care provider.