Background*

Mr. Hollings C. Renton, III., M.B.A served as the Chairman of Onyx Pharmaceuticals, Inc., from June 2000 to March 31, 2008 the Chief Executive Officer and President from March 1993 to March 31, 2008 and served as its Principal Financial Officer until April 12, 2006. He has over 25 years of experience building successful biotechnology companies, commercializing blockbuster products and forging industry-leading partnerships. Mr. Renton served as the President and Chief ... Operating Officer of Chiron Corporation since December 1991. He served as the President of Cetus Corporation from August 1990 to December 1991 and Chief Operating Officer from 1987 to August 1990. He joined Cetus in 1981 and served as its Chief Financial Officer from 1983 to 1987. During his tenure at Chiron Corporation and Onyx Pharmaceuticals, Inc. Mr. Renton demonstrated outstanding leadership qualities as well as a deep understanding of the opportunities and challenges faced by evolving pharmaceutical companies. He has been Chairman of The Board at Portola Pharmaceuticals, Inc. since March 09, 2010. He served as the Chairman of Affymax, Inc. since December 2009 to June 6, 2013. Mr. Renton has been a Director at Cepheid since March 2000. He has been a Director of Kythera Biopharmaceuticals, Inc. since January 05, 2015. He has been an Independent Director of Portola Pharmaceuticals, Inc., since March 9, 2010. He served as a Director of Affymax, Inc. from June 10, 2009 to November 2014 and as its Lead Director since December 1, 2009. Mr. Renton served as a Director of Biotechnology Industry Organization. He served as an Independent Director of Rigel Pharmaceuticals, Inc. from January 20, 2004 to March 30, 2014. He served as a Director of Onyx Pharmaceuticals Inc., from April 1992 to March 31, 2008. He served as a Director of Sangstat Medical Corporation since May 2002. He is a Director of Special Olympics Northern California. Mr. Renton holds an MBA degree from the University of Michigan and a BS degree in Mathematics from Colorado State University.

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