6Hans Moleman - The SimpsonsHans Moleman is a recurring character on the animated television series The Simpsons. He was created by series creator Matt Groening and is voiced by Dan Castellaneta, and first appeared in the episode "Principal Charming".

7Squidward - Spongebob SquarepantsSquidward Tentacles is a fictional character voiced by actor Rodger Bumpass in the American animated television series SpongeBob SquarePants.

In new ones, he's depressed until SpongeBob's diary changes everything. Then he reads it to the Krusty Krab and everyone hates him. he becomes a hobo but he thought it was worth it. In season 6, he entered a deep depression. It stopped in season 9, then he became a jerk. - Goatworlds

He can be sad sometimes, like when SpongeBob is harassing him. I think he is both a grumpy and sad person. - Minecraftcrazy530

I wouldn't say he is sad. He's just grumpy a lot. - cosmo

He's not really sad, he's more of a grumpy kind of person. - nintendofan126

10Fluttershy - My Little PonyFluttershy is a female pegasus pony from the 2010 animated TV show My Little Pony: Friendship is Magic. She is a kind pegasus and is very timid and shy. She takes care of the animals. She represents the element of kindness

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11Kenny McCormick - South ParkKenneth "Kenny" McCormick is a main character in the animated adult television series South Park, along with his friends Stan Marsh, Kyle Broflovski, and Eric Cartman.

This kid lives in a life of poverty, is physically and emotionally abused by his parents, his so-called friends don't even care about him half the time, and of course, constantly dies and comes back to life. Not only that, but because everyone's memories of his death are erased upon his revival, he has nobody to turn to. He has to deal with his curse alone. - DemonSpider253

12Ken Ichijouji - Digimon 02

13Rocko - Rocko's Modern LifeRocko is the eponymous fictional character of the cartoon Rocko's Modern Life and the comic book series of the same name.

14Old Gil - The Simpsons

15Lucy Loud - The Loud HouseLucy Loud is a fictional character in the Nickelodeon cartoon The Loud House. She was created by Chris Savino. Lucy is a goth and likes dark things.

16Pearl - Steven UniversePearl is a fictional character from the 2013 animated series Steven Universe, created by Rebecca Sugar. She is a "Gem", a fictional alien being that exists as a magical gemstone projecting a holographic body. ...read more.