Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LS-F11988 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the Quantitative detection of Human Leukotriene B4 Receptor / BLT1 in samples of Plasma and Serum. It is based upon a Sandwich assay principle and can be used to detect levels of Leukotriene B4 Receptor / BLT1 as low as 0.78 nanograms per millilter.

Sample Type:

Plasma, Serum

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Measurement:

Quantitative

Detection Range:

0.78 - 50 ng/ml

Sensitivity:

0.78

Precision:

Intra-Assay: CV<10% / Inter-Assay: CV<12%

Quality Assurance:

Due to their limited shelf life, LSBio ELISA kits are not typically stocked as finished goods. Upon receipt of an order each kit is assembled and tested to ensure that it meets specifications before shipping. Minor changes may occur to the Range, Sensitivity, and Precision. In the event of a significant change the order would be confirmed with the customer before shipping ELISA kit lot numbers reflect the date of final assembly and testing for each specific kit rather than a bulk manufactured lot. All kits are tested to confirm that they fall within their defined Inter- and Intra- assay coefficient of variation.

Description: BLT1 is a Chemoattractant Receptor that binds the potent chemoattractant leukotriene B4 (LTB4) which is involved in defense against infection. Leukotriene B4 also activates the transcription factor PPAR alpha, resulting in the activation of genes that terminate inflammatory processes (Yokomizo et al., 1997). Although BLT1 shows homology to other P2Y receptors, it does not function as a purinoreceptor ( Yokomizo et al., 1997).