The Clippers, who have done such a good job masking Blake Griffin’s absence, couldn’t match San Antonio’s depth in a 108-87 loss Tuesday night.

Big runs at the start of the second and fourth quarters against the Clipper reserves gave San Antonio comfortable separation, and strong games from Chris Paul, DeAndre Jordan, J.J. Redick and Jeff Green couldn’t overcome it.

Jamal Crawford hit his first field goal, an arcing jumper to put the Clippers ahead, 70-69.

But from there, the Spurs, led by reserves Patty Mills, Manu Ginobili and David West, dominated.

By the time Clippers coach Doc Rivers pulled the plug on his starters, San Antonio led by 18 points, a lead that ballooned to 21 by the final horn.

In the fourth quarter, the Spurs missed just six shots, as many as the Clippers made in the final 12 minutes.

It’s the first time the Clippers have lost consecutive games with Griffin out of the lineup.

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