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Scott Bartlett (Rory Culkin) is a typical 15-year-old boy growing up in late-1970s Long Island. His suburban existence is primarily marked by a nerdy interest in Star Wars, fending off bullies at high school, his longtime crush on neighbor/best friend Adrianna Bragg (Emma Roberts), and navigating the dysfunctional terrain of his parents' rocky marriage-all against the paranoid backdrop of a Lyme disease outbreak, which has freaked out Scott's high-strung mother, Brenda (Jill Hennessy), and has already claimed Adrianna's father, Charlie (Timothy Hutton), as a victim. With Charlie out of work due to his illness, Adrianna's mother, Melissa (Cynthia Nixon), takes a job working for Scott's father, Mickey (Alec Baldwin), a successful real-estate developer, and soon embarks on a messy affair. When eldest son Jimmy (Kieran Culkin) returns from army training and confronts his father about Mickey's less-than-discreet adultery, both families are forever changed by the devastating consequences.