Alice Otter was a humorous webcomic drawn in English by Spanish cartoonist Miguel Estrugo, started in July 15, 2001. It narrated the antics of a young anthropomorphized river otter girl called Alice Otter and her friends, schoolmates and relatives.

The humor in Alice Otter was based in character interaction, with occasional doses of absurd humor and surrealism; in general it was light-hearted, cute and whimsical.

Most of the action of the comic occurred in the suburbs of the imaginary town of Liroland, located in New England. The comic was occasionally set, or mentions, real places around the world, like Honolulu, Moscow or Dakar.

The website listed 167 strips as of February 2011, but was unavailable as of March 2012.[1]

Alice Otter is an anthropomorphized otter girl, very enthusiastic, curious and friendly, and the star of the strip. Her curiosity, manipulative nature and natural leaning to mischief ocasionally causes her and the people around her some problems. She's also intelligent and a little precocious for a child her age, but most of her woes and worries are related with the social environment

Garland Ferretti is Alice Otter's adoptive uncle and guardian (referred by Alice as Unclie Garland). He works as the director of the local newspaper's cultural suplement. Garland is a little stodgy, but also has a playful side, which Alice tries to unearth time after time to achieve her purposes. Being a ferret, he usually says, 'doooook' when he's startled, which is often. His car on the comic strip is a 1972 Fiat 127.

Ms. Sally Huskinson is a 30-something single husky woman and Alice Otter's math teacher, actively targeting Garland Ferretti to marry him so she can move out from her mother's house, for Alice Otter's despair. Despite her cute looks, she has a very bitter personality, but she tries to hide that fact when she's around Garland so she doesn't scare him away. She drives a 1980 Mazda 323.

Other characters in the strip were Libby a female dog girl, Alice's schoolmate and friend, usually ; Oliver Otter, a quiet otter boy who has a crush with Alice but is unable to tell her due to his shyness; Dan the Pony, an overly imaginative pony boy who befriends Alice during her trip to Hawaii, and Artie 'Roo, an adult, kangaroo friend of Alice and Garland, who usually sides with Alice when she confronts her uncle.