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Claims for Patent: 6,048,901

Claims for Patent: 6,048,901

Title:

Method of reducing intestinal gas, cramping and anorectal irritation

Abstract:

Intestinal gas, cramping and/or anorectal irritation are treated by oral administration of an effective or sufficient amount of a composition comprising polyethylene glycol, preferably dispersed and/or dissolved in an aqueous medium. The PEG compositions used for the present invention are desirably substantially free of ancillary electrolytes.

Inventor(s):

Cleveland; Mark vB. (Duxbury, MA), Pelham; Russell W. (Duxbury, MA)

Assignee:

Braintree Laboratories, Inc. (Braintree, MA)

Application Number:

09/348,376

Patent Claims:

1. A method of ameliorating symptoms relating to at least one of (a) intestinal gas, (b) cramping and (c) anorectal irritation, the method comprising the step of administering
an effective amount of a composition comprising polyethylene glycol.

2. The method of claim 1 wherein the composition is substantially free of electrolytes.

3. The method of claim 1 wherein the polyethylene glycol has an average molecular weight greater than 1000.

4. The method of claim 1 wherein the polyethylene glycol has an average molecular weight ranging from 3000 to 8000.

5. The method of claim 4 wherein the polyethylene glycol is PEG 3350.

6. The method of claim 1 wherein the composition comprises a dosage from about 5 to about 200 g of polyethylene glycol.

7. The method of claim 6 wherein the composition comprises from about 10 to about 30 g of polyethylene glycol per dose.

8. The method of claim 7 wherein the polyethylene glycol is dispersed in an aqueous medium.

9. The method of claim 7 wherein the polyethylene glycol is in solid form.

10. The method of claim 8 wherein the composition is administered up to four times per day.

11. The method of claim 1 wherein the ameliorated symptom is intestinal gas.

12. The method of claim 1 wherein the ameliorated symptom is cramping.

13. The method of claim 1 wherein the ameliorated symptom is anorectal irritation.

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