No, it is not used for herpes. METROGEL-VAGINAL (metronidazole) is indicated in the treatment of bacterial vaginosis (formerly referred to as Haemophilus vaginitis, Gardnerella vaginitis, nonspecific vaginitis, Corynebacterium vaginitis, or anaerobic vaginosis). It is also used to treat Trichomonas vaginalis which is a protozoan. Some of these can be sexually transmitted infections but they are not the same as herpes simplex Type 2. Herpes is a virus as Marvell noted.