Research profileThe Department of Drug Addiction Pharmacology (DAP) was founded in 2017 as a continuation of Drug Addiction Laboratory (established in 2006 as a unit in the Department of Pharmacology). The team is focused on studying various aspects of addiction to psychostimulants (amphetamine, methylenedioxyamphetamine, cocaine), nicotine, alcohol and THC. Study areas of the DAP include molecular and neurochemical mechanisms of addiction and possibilities for pharmacological intervention.

We closely cooperate with a number of scientific units in Poland (Department of Pharmacodynamics, Faculty of Pharmacy - Medical University of Warsaw, Department of Pharmacology and Pharmacodynamics, Faculty of Pharmacy - Medical University of Lublin) and abroad (Department of Nervous System Research - Karolinska Institutet, Faculty of Pharmacy - University of Ferrara, Department of Pharmacological and Biomolecular Research - University of Milan, Department of Psychiatry and Psychotherapy - University of Friedrich Alexander in Erlangen-Nürnberg).

The most important discoveries in the last 3 years- Amide derivative of N-acetylcysteine inhibits cocaine relapse in rats with experimental depression.- Tonic activation of A2A receptors located in the nucleus accumbens induces cocaine relapse.

Effects and potential mechanisms of action of dislufiram and nepicastat in morphine dependence in laboratory animal , Małgorzata Frankowska, PhD

, Professor Małgorzata Filip, PhD

The role of the mGlu5-D2 heterodimeric receptor complexes in the extinction of drug seeking behavior associated with dependents to psichostimulants (cocaine and MDMA): behavioral and biomolecular analyses in rats , Małgorzata Frankowska, PhD