Risk of Breast Cancer With Family History

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How much more likely is a person with a family history of breast cancer to get it than the rest of the population?

Answer

Gary Freedman, MD, Radiation Oncologist at Penn , responds:

In general, a woman in the United States has an approximate 1 in 9 chance of developing breast cancer by the age of 80.

A family history in a first degree (mom, sister) relative may be associated with a mild increase in risk, say 2 in 9.

A family history associated with a known genetic marker for breast cancer can be associated with very high rates of breast cancer. Usually, a woman with a family history can be evaluated by a genetic testing / risk assessment clinic at a local cancer center to determine if she should have genetic testing.

There is a great website available through the National Cancer Institute where a woman over age 35 can answer a 8-10 simple questions and get a statistic on her risk of cancer in the next 5 years and over her lifetime. The questions are about age, family history, prior biopsies, etc. Search on the web for "Gail Model" and the page at the National Cancer Institute website should come up.

Oct 14, 2010 - Following American Cancer Society (ACS) guidelines for physical activity, alcohol consumption, and body weight provides similar benefits for postmenopausal women with and without a family history of later-onset breast cancer (FHLBC), according to research published online Oct. 12 in Breast Cancer Research.