Hi there. While I'm waiting on a call from my sub doctor, I figured I'd try here. I just started on suboxone 1 8mg strip a day, my fiance has been on subs, off and on over the last year and A half his dose is 12mg, 1 and 1/2 strips. I'm going on my second week, 8 strips in. Yesterday, he developed hives while I was at work, later in the night, I started with them.

Is it common for someone to get a new reaction after having taking them for that long? I'm new to them, but I have taken them in the past as well. He seems to think it's definitely the subs since we are the only two in the house with subs and hives. He is also extremely irritable, worse than when he was dope sick.

Let me start by saying that I have no idea what to say! I just started the Suboxone route and am only in day 3. I just think it's weird that u and ur husband, who have either been on Subs for a while or done them before with no problems, both developed hives on the same night. Sorry to not b any help whatsoever!! I agree with Amy that u might need to look into something else. I developed hives one time and was on absolutely nothing. Never did figure out what caused it. Sorry again that I have nothing to add. Good luck! I will keep watching to see if u figure it out.

Likely not the subs in my very humble opinion. Just too coincidental to be likely. I'm voting something in your shared environment. Insects can do it. Also foods. Have you guys eaten anything unusual lately? More suggestions below:

Thanks all for the suggestions! I did receive a call back from the doctor and she said the same thing, it's more likely something in our environment. Nothing has changed, so I am at a total loss! On me, it's from my rib cage and up including my face, but my arms is only from the elbow up.

When I was in highschool, I was very stressed out and developed hives. I guess it was because I was really nervous and just started breaking out. I do think like the others, it's not from suboxone imo, it could be a lot of things that could cause it. Since u both developed it I'd assume it's something new....like Amy said.

Yes, I had one patient with hives from Suboxone-- one out of about 800 people over a course of 10 years. Two people getting hives from Suboxone, at the same time, would be extremely odd. And the idea that the hives would decrease after one day off medication doesn't make sense either, since 1. buprenorphine levels don't change much after one day, and 2. hive persist for at least a few days, after the cause of the hives is removed.

I had hives for a couple weeks when I was 16, working at True Value Hardware. I assume it came from one of the bags of lawn chemicals that I carried around as part of that job, but I kept the job and the hives went away-- so I never knew for sure.

I remember a statistic that a minority of people with hives ever determined the cause of the outbreak. The exact numbers escape me, but the point is that people get hives and usually don't know why.

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