Study selection and assessment:

randomised controlled trials (RCTs) that compared paracetamol with placebo or non-steroidal anti-inflammatory drugs (NSAIDs)
in patients who had radiographic evidence of OA or met American College of Rheumatology clinical criteria for OA or had pain
associated with OA. Quality of individual studies was assessed based on randomisation, blinding, and withdrawals.

Outcomes:

pain reduction from baseline, change in total Western Ontario and McMaster University (WOMAC) OA Index scores, change in function
and stiffness, and adverse events (gastrointestinal discomfort, nausea, headache, and dizziness).