Say hello to the latest cloud company to take an investment at a valuation of more than $1 billion. Coupa Software, a cloud startup that aims to help companies manage and control their spending, has closed an $80 million investment round.

Pacific Biosciences has worked hard over the past year and a half to demonstrate that its DNA sequencer, the RS II, can do something no other instrument can: assemble a whole human genome from scratch, without using an existing reference genome as a template. The process, known as de novo assembly, is harder and more costly than mapping to a reference genome, but it also reveals important information about the most complex types of variation in our genetic makeup.