Follow Sportsmail's coverage of the Six Nations Championship as Wales and Scotland clash at the Millennium Stadium in Cardiff to conclude their respective campaigns.

Wales need Dan Biggar and Mike Phillips to rediscover their best form as the fallen Six Nations champions undertake a salvage operation against struggling Scotland.

The defeat by England last Sunday has prompted head coach Warren Gatland to make six changes, including the enforced introduction of Liam Williams at full back for the injured Leigh Halfpenny.

Most focus at the Millennium Stadium will be on the return of the half-back pairing who first played together at the Ospreys.

Phillips has regained the No 9 jersey after his replacement, Rhys Webb, hobbled off last week, while Biggar took over following a nervous opening for Rhys Priestland at Twickenham.

Biggar sees his 23rd cap as a chance to lay down a marker for the summer tour of South Africa. And he predicts his former Ospreys colleague will respond positively to being dropped.

Follow every key pass, kick, scrum and crunching tackle right here with NIK SIMON. Join in the debate by tweeting nik_simon88.

Nik Simon

Host commentator

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16:34

FULL TIME: WALES 51-3 SCOTLAND

The final whistle could not come soon enough for the Scots and that's an absolute rout at the Millennium Stadium.

Sportsmail's Rob Robertson reports from Cardiff: After Hogg’s deserved red card it was always going to be a case of damage limitation for Scotland. Unfortunately from their point of view they failed to even make a good job of keeping the score down. Yet another sad and embarrassing day for Scottish rugby. Vern Cotter takes over from Scott Johnson in the summer. That day can’t come soon enough.

That's all from me, but stay tuned on Mail Online for the crucial fixture between Ireland and France.

16:30

79min: The Welsh keep coming

This is ruthless attacking from the Welsh and rarely have the Scots taken such a beating.

Wales are flinging the ball out the backdoor, smashing through their men and running the opponents ragged.

16:27

75min: TRY WALES! WILLIAMS! WALES 51-3 SCOTLAND

A brilliant finish as scrum-half Rhys Williams picks up a deft kick from James Hook.

That's Williams' first try in the red jersey and a fine score it was too.

Hook adds the extras, taking over the kicking duties from Biggar.

16:21

73min: Huge hit on Priestland

Wales launch a counter attack as Tipuric manages to skip past his defender.

The flanker has exceptional pace for a forward and feed Priestland.

The Welsh fly-half is one pass away from an inevitable try, but Taylor steps in with a massive tackle to hold up play.

16:17

70min: Sportsmail's Rob Robertson reports from Cardiff

Play is held up as Euan Murray tries to put in his contact lense. Not able to see this, even for a few moments, is a blessing for anyone connected with Scotland.

16:17

67min: Sportsmail's Rob Wildman reports from Cardiff

It’s all going right for Wales. The pack, maligned for that weak display in Dublin against Ireland, have just marched their opposing pack back after the Scots had set up to drive over from a line-out close in to the Welsh line. Whatever next for Wales? But the Six Nations title was lost in Dublin when Ireland took them apart, including a try from a line-out drive. The game has lost all shape. Too many substitutions.

16:11

64min: Poor decision making from the Scots

Scotland have a penalty advantage but work a good try-scoring position.

Weir tries a silly chip over the Welsh defence but it goes past Fife and straight into touch.

Nonetheless, play is pulled back for a penalty and Scotland kick for the lineout.

16:09

61min: Rare attack from Scotland

David Denton can often get lost among the rabble that is Scottish rugby but the No 8 is still a superb ball carrier.

The forward beats Roberts and just about gets his offload away, but the Welsh defence scrambles back to take the sting out of the attack.

16:02

58min: Sportsmail's Rob Wildman reports from Cardiff

Great stuff from Wales. That second try after half-time, scored by Roberts, was a memorable score. Liam Williams has excelled at full-back and his counter-attacking has been a feature of this afternoon. Scotland are finding it impossible to cover for the loss of Hogg. Debutant Fife has had a brutal introduction to international rugby. Faletau’s try has put Wales on course for a record win over Scotland. They scored 46 in 2005.

16:01

56min: Sportsmail's Rob Robertson reports from Cardiff

Scotland fans all over the world will be begging for this torture to end. 68-10 to South Africa is their worse ever defeat. Could Wales beat that today?

15:56

52min: TRY WALES! FALETAU! WALES 44-3 SCOTLAND

Sir Clive Woodward said this Scotland side would struggle to beat an Aviva Premiership side and he's not wrong based on this performance.

The Scottish defence slip off tackles and a series of Welsh offloads create the opportunity for Faletau to dive over in the right-hand corner.

15:51

47min: TRY WALES! ROBERTS! WALES 39-3 SCOTLAND

Scotland overthrow an attacking line-out and are punished as Warburton sweeps up the bouncing ball.

Williams runs the ball out of his own 22 before Davies, Faletau and Roberts combine to finish off a superb try.

Biggar adds the extras.

15:48

43min: Sportsmail's Rob Robertson reports from Cardiff

Look on the bright side. Euan Murray’s introduction at tight-head in place of Geoff Cross should improve the Scotland scrum.

15:45

42min: TRY WALES! NORTH! WALES 32-3 SCOTLAND

Quick thinking from Mike Phillips as Wales tap and go on the penalty.

Wales swing the ball through the hands and North is the final receiver on the left wing.

Without Hogg to cover, there's no stopping the Saints flyer.

15:43

We're back underway! Scotland kick off

There's a slight delay in waiting for the referee to emerge but Weir gets the show back on the road.

Alun-Wyn Jones is hoisted up by his lifters and claims the kick-off impeccably well.

15:37

Sportsmail's Rob Wildman sends his half-time thoughts from Cardiff

Game over here at 27-3. Wales have made Scotland pay for Hogg’s rashness through those two tries. George North needed his try. He’s had an indifferent tournament – too many turnovers – though he’s also not had much of an opportunity.

It was a good try off a counter-attack which will give Gatland some ammunition to throw back at his critics that his teams have come too predictable and one-dimensional. The reply will be ‘well, what are you beating?’ He can’t win in game like this where both set out to attack. Wales now need to come out and score some more. Easier said than done.

Wales' Dan Biggar is hit by Scotland's Stuart Hogg (L), who was subsequently sent off

15:32

HALF TIME: WALES 27-3 SCOTLAND

Biggar's conversion is the final kick of the first half.

Sportsmail's Rob Robertson reports from Cardiff: Hogg’s red card means it has to be a case of damage limitation for Scotland in the second-half.

15:30

39min: TRY WALES! ROBERTS! WALES 27-3 SCOTLAND

This is ruthless play from Wales as Jamie Roberts adds another try just before the break.

Davies made a dangerous break down the left and his centre partner was on the shoulder to collect a hopeful offload.

Biggar adds the extras.

15:28

38min: NO TRY! WALES!

Wales think they've scored a quick third but it's over-ruled for offside.

Davies triggered the move with a superb improvised kick but Faletau was offside.

15:24

35min: TRY WALES! NORTH! WALES 20-3 SCOTLAND

Liam Williams is having an impressive game in place of Leigh Halfpenny and the full-back makes a superb claim under the high ball to launch a Wales attack.

Excellent support lines keep the move alive and North is on hand to finish off the move, stepping inside his defender.

Biggar adds the extras.

15:24

33min: Sportsmail's Rob Wildman reports from Cardiff

Whatever happens the match will be forever remembered for Stuart Hogg’s departure. His late charge on Biggar deservedly brought him a red card after referee Jerome Garces watched the big screen replays. He had given the full-back a yellow at first only to change his mind after looking at the big screen. He may not have quite followed refereeing protocols but no Welsh supporter is arguing. It was a horrible challenge by Hogg. He led with his shoulder and can have no complaints.

15:21

31min: Another penalty to Scotland... but they don't go for goal this time

Laidlaw thinks otherwise about going for the three points.

Scotland kick for the corner and set up a platform from the line-out.

Without Hogg in the backline, it's going to be difficult for the Scots to find their way over the try line.

15:19

29min: Missed penalty! Scotland!

Scotland miss a second relatively simple kick at goal.

Laidlaw's not had his kicking boots in the opening half an hour and the score should be 13-9.

15:16

25min: Sportsmail's Rob Robertson reports from Cardiff

Stuart Hogg can have no complaints about being red carded. In doing so he becomes the third player in Scottish history to be sent-off following Nathan Hines in 2002 and Scott Murray against Wales, also in the Millennium Stadium, in 2006.

15:13

22min: Red Card! Hogg!

That's the end of Stuart Hogg's tournament! The full back hits Biggar in the chin with a late shoulder and it's an unsavoury moment.

Hogg's initially shown a yellow but, after checking the replay on the big screen, it's changed to a red card.

Biggar kicks the penalty to make it 13-3.

There's no way Scotland can hang in this game with 14 men.

15:03

15min: TRY WALES! WILLIAMS! WALES 10-3 SCOTLAND

Wales have too much for Scotland when they get going and their physicality in midfield is simply too poweful.

The hosts smash the ball at the Scottish defence, sucking in defenders, before swinging the ball out to the wing.

Williams applies a clinicial finish, with a bit of a showman's dive. He wasn't so cocky at Twickenham last week...

Biggar adds the extras.

15:03

14min: Sportsmail's Rob Wildman reports from Cardiff

Scotland were the first to settle but once Wales get hold the ball they are difficult opponents to budge. Wales need some composed play. Too many mistakes like last week at Twickenham.

That pass from Biggar which went over the head of North was a throwback to last week against England. Sad to see Kelly Brown going off. Despite his loss, Scotland must sense from the opening 12 minutes they have a real chance here but they need Laidlaw to kick his penalties. His second penalty attempt was a good effort from outwide on left but he needs to land them.

15:02

13min: Sportsmail's Rob Robertson reports from Cardiff

Ordinarily losing your captain so early would be a blow for Scotland but Alasdair Strokosch should be an able replacement for Kelly Brown who had to go off with a head knock.

15:01

11min: MISSED PENALTY! SCOTLAND!

Laidlaw misses a penalty to re-assert Scotland's lead and Wales clear the ball for a line-out.

The opening exchanges have been relatively open and Scotland have suffered an early injury blow after Kelly Brown suffered a knock to the head.

14:56

9min: PENALTY WALES! BIGGAR! WALES 3-3 SCOTLAND

It's time for some 'WarrenBall' as the hosts make their way into Scottish territory.

Roberts and Cuthbert throw their bodies at the Scottish defensive line but the blue wall doesn't crack.

Biggar throws the ball wide but the pass misses North and play is pulled back for a penalty, which is kicked by Biggar.

Scotland try to run the ball through the Wales midfield... good luck there.

14:47

Kick off! Wales get the game underway

Dan Biggar takes the kick-off but he switches direction and places the ball into the Scottish backs.

There's an early penalty for the Scots and Weir kicks for the corner.

14:45

National anthem time

Sing it loud and sing it proud. Both teams are out on field and the Welsh fans are in full voice.

This match doesn't hold the significance Wales had hoped for but the crowd are certainly out for a good time.

Stay tuned for all the action.

14:42

Sportsmail's Rob Robertson reports from Cardiff

Scott Johnson has got his wish and the Millennium Stadium roof is closed. The question is will his Scotland back division see enough of the ball to play running rugby as he has claimed they will?

14:38

Sportsmail's Rob Wildman reports from Cardiff

A full house is expected in the Millennium Stadium. Evidently, tickets for his match sold out more quickly than for the game against France which was staged here on a Friday night.

And, like the France match, the roof is closed. It might be spring outside – sunny and a bit windy – but the two teams have opted to have the roof closed. Expect plenty of points. Both teams want to finish on a high after disappointing tournaments. Pride is at stake in this Celtic Derby which stretches back 128 years.

For the historians, this is the 100th international to be staged since the Millennium Stadium was built. Game No 1 was Wales’ famous 29-19 win over South Africa on June 26, 1999. It still remains Wales’ only win over the Springboks and was watched by a crowd of 28,000 because the stadium was not quite complete.

14:36

Welcome to Sportsmail's live coverage of Wales vs Scotland

Wales have won the toss and will kick off at the Millennium Stadium.

Warren Gatland's side are on a mission to restore some pride and that could prove deadly for Scotland.