Juliet Rylance will produce with Barbara Romer, the founder and CEO of New Globe Theater.

Camargo wrote the script for the indie pic, which will be set in rural New England where reckless desire wreaks havoc over Memorial Day weekend as a family confronts the volatile and fragile nature of love.

Janney will play Elizabeth, a movie star based on the role of Irina Arkadina in “The Seagull.” Hurt will play her ailing brother, while Holmes will play the temperamental daughter of the estate’s caretaker.

Production is skedded to start this summer in upstate New York, although exact dates have yet to be decided.

“[Christian’s] script is delicately and beautifully written, with all the humor, desperation and longing that are synonymous with Chekhov,” said Juliet Rylance.

Another star-studded ensemble put on “The Seagull” in 2001, when Meryl Streep, Kevin Kline, Christopher Walken, Natalie Portman, Philip Seymour Hoffman, John Goodman and several other stars put on a series of free summertime shows at the Delacorte Theater in New York City’s Central Park.

Holmes, repped by CAA and John Carrabino Management, is coming off “Don’t Be Afraid of the Dark.” ICM-repped Hurt is currently filming Andrew Niccol’s adaptation of “The Host” for Open Road. Janney, who recently starred in “The Help” and “Margaret,” next appears in “Struck By Lightning.” She’s repped by WME and Thruline Entertainment.

ICM-repped Reno co-stars alongside Tyler Perry in “Alex Cross,” while Means appears in the adaptation of Judy Blume’s “Tiger Eyes.” Mark Rylance recently appeared in Roland Emmerich’s “Anonymous,” while Juliet Rylance will soon be seen in Scott Derrickson’s “Sinister.”

Camargo played the Ice Truck Killer on the first season of “Dexter” and will reprise his role as Eleazar Denali in Summit’s “The Twilight Saga: Breaking Dawn — Part 2.” He’s repped by Innovative Artists, Wishlab and attorney Jodi Peikoff.