Product Introduction

Coluracetam
(MKC-231) is a synthetic Racetam drug purported to be a Nootropic compound. It
does not have a large body of evidence investigating it, but the mechanisms of
action (as well as structute) appear to be very distinct from other racetam
compounds like Piracetam or Aniracetam.

How Coluracetam (MKC-231)
works ?

Coluracetam
appears to interact with a process known as high affinity choline uptake (HACU
for short), which is the rate-limiting step of drawing choline into a neuron
for synthesis into the neurotransmitter acetylcholine. Increasing the HACU rate
appears to increase the activity of cholinergic neurons, so it is a desired
target for cognitive enhancement.

Coluracetam
has a lot of characteristics in common with other Racetams, but there are also
some important distinctions. It is thought to work by increasing Choline uptake
into neurons, even if they are already impaired or damaged. Some evidence
suggests that Coluracetam might be particularly effective in the areas of the
brain involved in visual processing.

Dosages
and Suggestion

Suggested doses for supplement use are
based on rat studies and thus were recommended to be between 2.5 – 3 mg/kg
orally.

In the patent for coluracetam as treatment
for depression and anxiety, the dose used ranged from 80 mg orally once to
three times daily.

Coluracetam is commonly dosed from 50-150
mg with most nootropic users.