Precautions

Administration

• Make sure patient swallows tablets whole without chewing.• Don't give tablets within 1 hour of dairy products or antacids (may break down enteric coating).• Know that drug should be used only for short periods.

Patient monitoring

Patient teaching

• Instruct patient to swallow (not chew) enteric-coated tablets no sooner than 1 hour before or after ingesting antacids or dairy products. Tell him not to chew tablets.• Advise patient not to use bisacodyl or other laxatives habitually because this may lead to laxative dependence.• Suggest other ways to prevent constipation, such as by eating more fruits, vegetables, and whole grains to increase dietary bulk and by drinking 8 to 10 glasses of water daily.• As appropriate, review all other significant and life-threatening adverse reactions and interactions, especially those related to the drugs, tests, and foods mentioned above.

bisacodyl

/bis·ac·o·dyl/ (bis-ak´ah-dil) (bis″ah-ko´dil) a contact laxative, used as the base or as a complex with tannic acid (b. tannex) .

bisacodyl

(bĭs-ăk′ə-dĭl, bĭs′ə-kō′dĭl)

n.

An over-the-counter laxative taken by mouth or per rectum to treat constipation.

bisacodyl

[bisak′ōdil]

a cathartic.

indications It is prescribed in the treatment of acute or chronic constipation or for emptying of the bowel before or after surgery or before diagnostic radiographic procedures.

All patients underwent bowel preparation with bisacodyl (Dulcolax) 10-mg tablets (2 tablets taken immediately after a meal on night before deworming), followed by praziquantel (25 mg/kg in 2 doses 4 h apart), and 30-g magnesium sulfate granules, dissolved in 1 cup of milk, given 1 h after the second dose of praziquantel.

The 2 most frequently abused laxatives are bisacodyl (the active ingredient in Ex-Lax[R], Correctol[R], and Dulcolax[R]) and anthraquinones such as senna (the active ingredient in Senokot[R], Castoria[R], and Black Draught[R]) (8,19-21).

25) Some patients with intractable constipation had a minimal colonic motor response to intraluminal bisacodyl (25) or cholinergic stimulation with anticholinesterases, (22) compared with normal control subjects.

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