Influence of dietary state and insulin

Effects of zinc and other nutritional factors on insulin-like growth factor-I and insulin-like growth factor binding proteins in healthy post-menopausal women. Hide All 1Department of Health. Insulin-like growth factors and their binding proteins: It is thus possible to study myocardial substrate metabolism and its determinants in intact animals rather than in isolated hearts.

This article has been cited by other articles in PMC. The purpose of the current study was to determine, if myocardial [18F]-fluorodeoxyglucose FDG kinetics in mice in a non-fasting condition or a fasting condition differ after injection of insulin and furthermore assess the effect on FDG kinetics in the muscle and brain.

Accordingly, only few investigations have attempted to measure glucose metabolic rates in the myocardium, skeletal muscle, and brain in mice or rats [ 1 - 6 ]; many of them addressed mainly methodological aspects. When assessing the effect of insulin on the myocardial glucose Influence of dietary state and insulin of non-fasted mice, it is not sufficient to just calculate the SUV - dynamic imaging with kinetic modeling is necessary.

Cross cultural assessment of diet in three population samples of African origin from Cameroon, Jamaica and Caribbean migrants to the UK: Fasting led to a reduction in glucose metabolic rate in the myocardium Background The development of high-spatial-resolution small-animal PET has opened a new field for translational research.

The small organ size in these animals, together with limitations in blood sampling, poses considerable methodological challenges.

Importantly, because PET allows simultaneous measurements of radiotracer uptake and tissue kinetics in multiple organs such as skeletal muscle, brain, and myocardium, system-wide response of individual organ metabolic rates to physiological or pharmacological stimuli can be evaluated.

Cancer and insulin-like growth factor-I. Environmental and heritable factors in the causation of cancer — analyses of cohorts of twins from Sweden, Denmark and Finland.

Calorie restriction delays spontaneous tumourigenesis in pknockout transgenic mice. Epidemiology of the insulin-like growth factor system in three ethnic groups.

Role of the insulin-like growth factor family in cancer development and progression. Knowledge of the extent of these changes will assist in planning future experiments for assessing glucose metabolism to help decide if kinetic modeling is necessary or which metabolic state would be the most suitable to answer the scientific question.

i values were increased by insulin independent of dietary state, whereas in the brain, those parameters were not influenced by fasting or administration of insulin. Fasting led to a reduction in glucose metabolic rate in the myocardium ( ± vs.

± mg/min/ g; p. Skeletal muscle SUVs and K i values were increased by insulin independent of dietary state, whereas in the brain, those parameters were not influenced by fasting or. Influence of dietary state and insulin on myocardial, skeletal muscle and brain [18F]-fluorodeoxyglucose kinetics in mice.