MIAMI -- Everything was clicking for the San Diego Padres in the first two innings.

They sent 22 men to the plate, racked up 14 hits, and scored 13 runs.

"It was one of those night where you could have brought Bob Feller back, Tom Seaver back and (San Diego) probably would have done just as well," Marlins manager Jack McKeon said. "No matter who you put out there, they're going to hit."

"Very rarely do you hit balls hard and soft and they're all finding holes," Ludwick said. "And that's what happened."

Will Venable homered, scored three runs, and reached base four times for the Padres, who set a season-high in runs while the 20 hits were the second-highest.

"We talk about hitting being contagious and tonight was a testament to that," Padres manager Bud Black said.

Venable led off the game with a home run to right field off Ricky Nolasco (6-7). The Padres scored four in the first and nine in the second to build a 13-0 lead.

"That type of game is a rarity when you have that many runs in the first two innings," Black said.

Ludwick had a two-run double and a two-run single during the two-inning barrage while Guzman added a three-run double.

"(Nolasco)'s got good stuff," Ludwick said. "We were just in attack mode."

In the nine-run second inning, the Padres sent 13 men to the plate including seven straight who reached base safely. It was the most runs by the Padres in an inning since scoring 10 on April 12, 2010, against Atlanta. Venable led off the inning with a base hit and scored twice in the frame and Harang had a run-scoring single. Only a base-running mishap by Jason Bartlett ended the inning.

"There's a good feeling because once you start getting hits and everybody is contributing you feel as though it's not going to stop," Black said. "There's a great sense of confidence throughout the lineup and everybody can't wait to get to the plate."

Nolasco allowed nine runs in 1 1/3 innings -- the shortest start of his career -- which raised his ERA from 3.51 to 4.08. Burke Badenhop followed and allowed four runs in 2 2/3 innings.

"I was just trying to battle, just trying to find a way," Nolasco said. "The worst start of my career. The thing I tell myself is you can't let this affect my next start. I have to go out there in five days and try to get back to where I was."

Aaron Harang (8-2) waited 39 minutes between pitches after the first inning, but it did not faze him as he retired the Marlins in order. He had his scoreless-innings streak snapped at 16 1/3 when Mike Stanton hit an RBI single in the fourth.

"That down time can really throw you off so of course you want to go out and throw strikes, have a fast inning so we can get back up to the plate," Harang said. "It's difficult with that extra time off."

Harang pitched 5 1/3 innings and allowed three runs to pick up the win.

Guzman's three hits were a career-high and it was his second four-RBI game in the last four.

Marlins third baseman Emilio Bonifacio extended his hitting streak to 19 games with a line-drive single in the fifth.

"I don't know if anybody knew I pitched in college," Petersen said. "I was trying to get outs as soon as possible."

Game notes

The Padres' 14 runs were their most in Miami since an 18-2 win on Aug. 23, 2002. ... The last time the Padres had two players with at least four RBIs in the same game was Aug. 10, 2008, when Luke Carlin and Brian Giles both had four in a 16-7 win at Coors Field. ... Nolasco's shortest start in the big leagues came in his 136th start. ... Marlins veteran infielder Wes Helms made his first career appearance at second base. ... The last Marlins position player to pitch in a game was Ross Gload on May 22, 2009, against Tampa Bay.