Neurologic Complications of Cancer

Lisa M DeAngelis and Jerome B Posner

Description

Patients with cancer can suffer from a bewildering variety of neurologic signs and symptoms. The neurologic symptoms are often more disabling than the primary cancer. Symptoms including confusion, seizures, pain and paralysis may be a result of either metastases to the nervous system or one of several nonmetastatic complications of cancer. The physician who promptly recognizes neurologic symptoms occurring in a patient with cancer and makes an early diagnosis may prevent the symptoms from becoming permanently disabling or sometimes lethal. This monograph, an update of the first edition published in 1995, is divided into 3 sections. The first classifies the wide variety of disorders that can cause neurologic symptoms the patient with cancer, discusses the
pathophysiology of nervous system metastases, the pathophysiology and treatment of brain edema and the approach to supportive care of common neurologic symptoms such as seizures, pain, and side effects of commonly used supportive care agents. The second section is devoted to nervous system metastases, addressing in turn, brain, spinal cord, meningeal and cranial and peripheral nerve metastases, describing clinical symptoms, approach to diagnosis and current treatment. The third section addresses several nonmetastatic complications of cancer and includes sections on vascular disease, infections, metabolic and nutritional disorders, side chemotherapy, radiation and other diagnostic and therapeutic procedures. The final chapter addresses paraneoplastic syndromes.

The book is
intended for practicing oncologists, neurologists, neurosurgeons and radiation oncologists as well as internists who treated patients with cancer. Our attempt was to write a book that would assist oncologists in understanding neurologic problems and neurologists in understanding oncologic problems. The book is also intended for physicians training to specialize in any of the above areas. It includes a practical approach to the diagnosis and management of patients with neurologic disease who are with known to have cancer or in whom cancer is suspected.

Neurologic Complications of Cancer

Lisa M DeAngelis and Jerome B Posner

Reviews and Awards

"This new edition by DeAngelis and Posner is invaluable not only in understanding the pathophysiology of this established field--both authors are recognized pioneers--but also provides specific traetment options in handling these unfortunate complications....There is very little in this book [that] does not affect the practice of the neurointensivist. Now thoroughly updated and modernized, this is an enormously worthwhile book."--EFM Wijdicks in Neurocritical Care

"...This seminal book by two of the world's most experienced and respected neuro-oncologists is an impressive example of excellent cooperation focusing on particular diseases or conditions related to cancer and the nervous system. It will be a reference guide which should not be missed on the bookshelfs of (neuro)-oncologistss and related health professionals."--K.A. Jellinger in European Journal of Neurology

"This book will help all physicians who encounter neurologic complications in a patient with known or suspected cancer. Jerome Posner, one of the book's two authors, is a worldwide expert on the neurologic complications of cancer....Lisa DeAngelis is the current chair of the department of neurology at Memorial Sloan-Kettering. This second edition of Neurologic Complications of Cancer was necessary because of the important advances that have been made in the field of neuro-oncology since 1995, when the previous edition was published....The authors include a practical approach to the diagnosis and treatment of patients....The book will be useful to physicians--whether they specialize in neuro-oncology or not--and to nurses as they seek to improve the quality of their
patients' lives."--New England Journal of Medicine

"...this concise but comprehensive textbook is to be recommended..."--The Lancet Neurology

"The new edition of Neurologic Complications of Cancer covers in meticulous detail every aspect of neuro-oncology. The chapters follow the same structure as its predecessor and are well proportioned for the modern reader. It provides an exhaustive review of the literature: 4239 references. Yet, because the authors have each made many major personal contributions to the subject matter of most chapters in the evolving story of neuro-oncology, they write from deep personal knowledge and experience of their subject. Nowadays many of us use electronic data for factual information and open a book to find the expression of an authoritative personal view and critical knowledge. As with its predecessor published in 1996, the re-written edition of Neurologic Complications of Cancer
by Lisa DeAngelis andJerome Posner is a wonderful combination of both media."--BRAIN

"A profound knowledge of Neurologic Complications of Cancer is...essential for all clinical neurologists. Few experts would question the notion that nobody could provide a more authoritative review of this topic than Lisa M. DeAngelis and Jerome B. Posner....A series of helpful tables summarize common oncology scores as well as algorithms for diagnosis and treatment. The schematic and original illustrations of macropscopic and microscopic pathology as well as neuroimaging represents a superb collection of such materials....Altogether, this update of the already historic first edition published in 1995 is a comprehensive source of knowledge that is very well organized and extremely useful as a from-the-shelf reference for daily clinical practice as well as for teaching
purposes."--Archives of Neurology

"This second edition of 'Neurological complications of cancer', with the addition of Dr. DeAngelis as a co-author, once again will become a most valuable resource for practicing neurologists and neurosurgeons...a magnificent reference text."--Journal of the Neurological Sciences

"Neurologic Complications of Cancer, now coedited by Jerome Posner and Lisa DeAngelis, remains unreached by its ever-increasing number of competitors. The book is clinical yet scientific, practical yet academic, comprehensive yet readable, a timeless classic yet now, the latest. In times in which quantity beats quality to the spotlight and the quantity of a medical publication is measured by the amount of evidence-based information presented, it is refreshing to read the work of outstanding clinicians who can put published evidence into the context of their wealth of personal clinical experience."--Reviewed by Joachim M. Baehring, MD, DSc in Neurology