Sarcoidosis

Treatment in Neurosarcoidosis

01/04/2011

Question:

I`m a pediatrician and my friend was diagnosed sarcoidosis in August. He had problems in his limphatic system,liver, lungs and spleen. Prednisone made to be better his affected organs but he started neurological symptoms ( language and visual problems)a month later. Resonance make the diagnosis (he has affected the left brain (white matter). His treatment is prednisone and ciclophosphamide.Is there some specific hospital or doctor with experience that you Know?

Answer:

Dear Doctor- Neurosarcoidosis can be challenging to diagnose and treat. Corticosteroids and cyclophosphamide can be an effective regimen; however, the risk of bladder cancer is very high in patients treated with cyclophosphamide for long periods of time, which is likely to be the case for neurosarcoidosis. Reasonable alternatives to cyclophosphamide exist (e.g., methotrexate, anti-TNF drugs, azathioprine), and it is best that these drugs are managed by experienced experts.

Regional experts in the management of sarcoidosis can be found by searching the Foundation for Sarcoidosis Research website (http://www.stopsarcoidosis.org/) under the "Patient Info" drop-down menu. Sincerely, Elliott Crouser.

Please note: only your personal physician or other health professional you consult can best advise you on matters of your health based on your medical history, your family medical history, your medication history, and how information from any of these databases may apply to you. Neither University of Cincinnati (NetWellness) nor any party involved in creating, producing or delivering this web site shall be liable for any damages arising out of access to or use of this web site, or any errors or omissions in the content thereof. (More)