Diagnosis at Mayo Clinic

Your doctor may use the following exam and tests to determine if you have Waldenstrom macroglobulinemia. In tests that use radiation, specialists carefully monitor doses to avoid the risk of radiation overexposure.

Physical exam. Your doctor will perform a physical exam to determine any health changes you may have, such as enlarged lymph nodes.

Laboratory tests. Laboratory tests can show changes in your blood cells, blood chemistry and your urine. Blood tests can also tell your doctor if you have the IgM protein, a sign of Waldenstrom macroglobulinemia.

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