Fusion

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

slr0605

Hypothetical protein (319 aa)

Predicted Functional Partners:

slr0306

Hypothetical protein (506 aa)

0.600

sll0654

Alkaline phosphatase (1409 aa)

0.600

lepA

LepA gene product; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (603 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

lepA

slr0605

SYNGTS_3165

SYNGTS_3166

LepA gene product; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner

Hypothetical protein

0.581

lepA

slr0606

SYNGTS_3165

SYNGTS_3167

LepA gene product; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner

Hypothetical protein

0.440

sll0654

slr0605

SYNGTS_0380

SYNGTS_3166

Alkaline phosphatase

Hypothetical protein

0.600

sll1773

slr0605

SYNGTS_1092

SYNGTS_3166

Hypothetical protein; Putative quercetin 2,3-dioxygenase

Hypothetical protein

0.494

slr0199

slr0605

SYNGTS_2455

SYNGTS_3166

Hypothetical protein

Hypothetical protein

0.483

slr0306

slr0605

SYNGTS_2710

SYNGTS_3166

Hypothetical protein

Hypothetical protein

0.600

slr0605

lepA

SYNGTS_3166

SYNGTS_3165

Hypothetical protein

LepA gene product; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner

0.581

slr0605

sll0654

SYNGTS_3166

SYNGTS_0380

Hypothetical protein

Alkaline phosphatase

0.600

slr0605

sll1773

SYNGTS_3166

SYNGTS_1092

Hypothetical protein

Hypothetical protein; Putative quercetin 2,3-dioxygenase

0.494

slr0605

slr0199

SYNGTS_3166

SYNGTS_2455

Hypothetical protein

Hypothetical protein

0.483

slr0605

slr0306

SYNGTS_3166

SYNGTS_2710

Hypothetical protein

Hypothetical protein

0.600

slr0605

slr0606

SYNGTS_3166

SYNGTS_3167

Hypothetical protein

Hypothetical protein

0.448

slr0606

lepA

SYNGTS_3167

SYNGTS_3165

Hypothetical protein

LepA gene product; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner

0.440

slr0606

slr0605

SYNGTS_3167

SYNGTS_3166

Hypothetical protein

Hypothetical protein

0.448

Network Stats

Network Stats analysis is still ongoing, please wait ...

Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: