The best way to get from Manuel Antonio National Park to Panama Canal is to bus and Microbus which takes 13h 59m and costs $90 - $130. Alternatively, you can fly, which costs $100 - $390 and takes 8h 5m.

Panama City is the capital and largest city of the Republic of Panama. It has an urban population of 430,299, and its population totals 880,691 when rural areas are included. The city is located at the Pacific entrance of the Panama Canal, in the province of Panama. The city is the political and administrative center of the country, as well as a hub for international banking and commerce. It is considered a "gamma+" world city, one of three Central American cities listed in this category.
- Wikipedia

Things to do in Panama City

Soberanía National Park (Parque Nacional Soberanía) is a national park in Panama near the banks of the Panama Canal in the provinces of Panamá and Colón, some 25 km from Panama City. The Chagres River runs through the park. Established as a national park in 1980, the park covers 55000 acre.

Panama City is the capital and largest city of the Republic of Panama. It has an urban population of 430,299, and its population totals 880,691 with 1,526,421 in its metropolitan area. The city is located at the Pacific entrance of the Panama Canal, in the province of Panama. The city is the political and administrative center of the country, as well as a hub for international banking and commerce. It is considered a "Beta-" world city, one of three Central American cities listed in this category.

Casco Viejo (Spanish for Old Quarter), also known as Casco Antiguo or San Felipe, is the historic district of Panama City. Completed and settled in 1673, it was built following the near-total destruction of the original Panamá city, Panamá Viejo in 1671, when the latter was attacked by pirates. It was designated a World Heritage Site in 1997.

The Bridge of the Americas (Spanish: Puente de las Américas; originally known as the Thatcher Ferry Bridge) is a road bridge in Panama, which spans the Pacific entrance to the Panama Canal. Completed in 1962, at a cost of US$20 million, it was the only non-swinging bridge (there are two other bridges, one at the Miraflores locks and one at the Gatun locks) connecting the north and south American land masses until the opening of the Centennial Bridge in 2004. The bridge was designed by Sverdrup & Parcel.

Rome2rio is a door-to-door travel information and booking engine, helping you get to and from any location in the world.
Find all the transport options for your trip from Manuel Antonio National Park to Panama Canal right here. Rome2rio displays up to date schedules, route maps, journey times and estimated fares from relevant transport operators, ensuring you can make an informed decision about which option will suit you best. Rome2rio also offers online bookings for selected operators, making reservations easy and straightforward.