Immediately prior to moving to Crispin Porter & Bogusky, Senecal was executive chairman of its sister agency KBS from August 2014. She joined the latter agency in 2009 as president and chief executive, as it rebranded from Kirshenbaum Bond & Partners to Kirshenbaum Bond Senecal & Partners (now KBS).

Before moving to KBS Senecal was president of McCann New York (then McCann-Erickson, New York).