In this paper I present the Discrete Space-Time Thesis, in a way which enables me to defend it against various well-known objections, and which extends to the discrete versions of Special and General Relativity with only minor difficulties. The point of this presentation is not to convince readers that space-time really is discrete but rather to convince them that we do not yet know whether or not it is. Having argued that it is an open question whether or not space-time is discrete, I then turn to some possible empirical evidence, which we do not yet have. This evidence is based on some slight differences between commonly occurring differential equations and their discrete analogs.