CBpromise

arhgef1

Official Full Name

Rho guanine nucleotide exchange factor (GEF) 1

Background

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that;work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate;Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the;full-length nature of some variants has not been defined.