Store at -20° to -70°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.

Structural Form

Truncated/Recombinant

Protein Subtype

Interleukins|Cytokine Receptors

Endotoxin Concentration

<1 EU/μg

Gene Alias

IL6ST, 5133400A03Rik, AA389424, BB405851, CD130, D13Ertd699e, gp130

Common Name

Interleukin 6 signal transducer

Gene Symbol

IL6ST

Protein Tag

His Tag

Validated Application

Assay Standard

Protein Family

Cytokines & Receptors/CD Proteins

Expression System

Mammalian

Interleukin 6 signal transducer (IL6ST), recombinant mouse protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, and cell biology research applications. It can also be used as an immunogen, or as a protein standard.

Activity: 1. Measured by its ability to bind mouse IL11RA in a functional ELISA; 2. Measured by its ability to inhibit the IL6R enhancement of IL6 activity on M1 mouse myeloid leukemia cells (Saito, T. et al. 1991, J. Immunol. 147:168), the ED50 for this effect is typically 0.2-0.8μg/mL in the presence of 50ng/mL recombinant human IL6sR and 100ng/mL recombinant human IL6