Articles from March 2017

Growing up nestled in the heart of the Rocky Mountains, I had the opportunity to hike some of the most rugged mountains in the western United States. As I help code the nlmixr FOCEI likelihood surfaces I can’t help but draw some parallels between two of my hikes in these

There’s a distinct shortage of tools for performing effective pharmacometric data analysis. There’s NONMEM, the gold standard; there’s Monolix; and there’s Phoenix WinNonlin. All of these tools do a good enough job, but are united by two critical issues: first, they’re closed and proprietary, and second, they cost the equivalent of a

nlmixr

nlmixr is an R package for fitting general dynamic models, pharmacokinetic (PK) models and pharmacokinetic-pharmacodynamic (PKPD) models in particular, with either individual data or population data. It's free and open source, and will remain so.

Our development team is led by Wenping Wang (@wenping_wang), and is composed of Matt Fidler, Rik Schoemaker, Justin Wilkins (@JustinWilkins), Mirjam Trame and Yuan Xiong (@yxiong).