RNA Interactions - a PDE Story

When

Start: 09/18/2017 - 4:15pm End : 09/18/2017 - 5:15pm

Category

Applied Math Seminar

Speaker

Maryann Hohn (UCSD)

Abstract

Small non-coding RNAs regulate developmental events through certain interactions with messenger RNA (mRNA). By binding to specific sites on a strand of mRNA, small RNAs may cause a gene to be activated or suppressed, turning a gene "on" or "off". To better understand these interactions, we developed a mathematical model that consists of a system of coupled partial differential equations describing mRNA and small RNA interactions across cells and tissue. In this talk, we will discuss the mathematical models created and numerical simulations using these equations.