Water-Soluble Granules

Improving water solubility and bioavailability of APIs.

Labo Smeets (Wilrijk, Belgium) has developed in collaboration with Ghent University a technique to produce water-soluble granules containing poorly water soluble drugs of Class II (poorly soluble, highly permeable) or Class IV (poorly soluble, poorly permeable) of the Bio Classification System (BCS).

The innovative and patented technology can be used for the production of water-soluble granules of human or veterinary medicines. First applications are the production of granules of antibiotics administered via drinking water to treat large groups of animals (poultry, pigs,) as opposed to administering these antibiotics via the food. The produced granules can also be filled in capsules or can be used as intermediates for the production of tablets