Griffin has been a huge supporter of his alma mater. Last year, he made a $150 million donation to the school.

Griffin explained that when making a hire he wanted to bring on the "best and brightest in markets."

"So one of the great advantages that I had in my career is I started trading 24 hours a day in my early 20s, and I had to learn to delegate to people," he said. "I had to learn to trust people, and I realized that success was going to be born in hiring really bright people — very self-motivated, very able to make good judgment calls day in and day out.

"And if you look at Citadel today, that's really the founding principle of the firm is a real pursuit of talent, a pursuit of people who have a passion for finance, and a pursuit of individuals who make good decisions day in and day out."