Kinetics of the luminescence intensity is studied for blood serum and its components applied on a standard substrate. The luminescence appears as a result of triboelectrization by the rotating polytetrafluorethylene cylinder under constant conditions. Triboluminescence of electrolytes has been higher than that of amino acids, glycerol and glucose and increased with the substance concentration growth. Maximal intensity of the triboluminescence has been revealed in cholesterol and fatty acids as well as in lyophilized human serum albumin. It is supposed that parallel with electrolytes, it is lipids, exactly radical products of their oxidation formed under conditions of triboluminescence and oxygen access, that are basic emitters of visible radiation in triboluminescence.