Priligy was discovered as an antidepressant medicine but was found to be very effective in treating premature ejaculation. It is rapidly absorbed and eliminated from the body and that makes it ineffective as an antidepressant. But its action improves the time of ejaculation after vaginal penetration, therefore, it became popular as a treatment for PE.

Class and Mechanism of Action

Priligy or Dapoxetine is an SSRI – selective serotonin reuptake inhibitor. Serotonin is a neurochemical which controls the ejaculatory function. Priligy inhibits the compound that transports the serotonin thereby increasing its levels in the brain. This increases the action of serotonin on the postsynaptic cleft in the brain and delays the ejaculation.

Looking after your drug

Store it in a cool and dry place away from the reach of children.

How to take the medication?

Take it orally at least 1 - 3 hours prior to a sexual activity.

Dosage

The dose is one pill per day. It is taken on as per the need basis.

Overdose

Seek medical help right away.

Missed Dose

The chance of a missed dose is unlikely since it is taken as per the need. Do not take more than one pill in a day.

Warnings and Precautions

Do not use along with recreational drugs, MAOIs, CYP3A4 inhibitors or with other SNRIs. Do not use if you are under 18 years of age or very elderly. Not recommended for males who are not diagnosed with PE.

Possible Side Effects

· Dry mouth, nausea, diarrhoea

· Dizziness

· headache

· Insomnia, fatigue

· Nasal congestion or a runny nose

When should Priligy not be used?

Heart disorders, conduction disorders, history of orthostatic hypotension or syncope, manic or severe depression, along with MAOIs, CYP3A4 inhibitors or with other SSRIs or SNRIs.