Calcium Phosphate

Calcium phosphate ADJUVANT is a sterilized wet gel suspension which has been sterilized by gamma-irradiation in the final container.

It tolerates autoclavation, but is destroyed if frozen. When the pH is maintained at 6-8, which is normal during vaccine production, calcium phosphate particles have a negative electrical charge so they readily adsorb positively charged antigens (e.g. proteins with alkaline isoelectric points at neutral pH).