A new study led by University of Kentucky researchers suggests a new approach to develop highly-potent drugs which could overcome current shortcomings of low drug efficacy and multi-drug resistance in the treatment of cancer ...

Current drugs block the actions of only about a quarter of known disease-causing proteins, but Yale University researchers have developed a technology capable of not just inhibiting, but destroying every protein it targets.

A new study shows that it is possible to use an imaging technique called cryo-electron microscopy (cryo-EM) to view, in near-atomic detail, the architecture of a metabolic enzyme bound to a drug that blocks its activity. ...

Using DESY's ultra bright X-ray source PETRA III, scientists have resolved the molecular structure of two promising drug candidates from the new group of Spiegelmers for the first time. The results provide a deeper understanding ...

Most of today's anticancer drugs target the DNA or proteins in tumor cells, but a new discovery by University of California, Berkeley, scientists unveils a whole new set of potential targets: the RNA intermediaries between ...

An international team of researchers has shed light on the molecular mechanism behind the importance of water for functional protein dynamics. The scientists have discovered that water's ability to flow on the surface of ...