What Are Nootropics

Now that you have come to the best place to buy nootropics online, it is important to know what Nootropics are prior to making a purchase. In today's day and age, Nootropics are a broad term used for any psychotropic compound that has the ability to boost the overall performance, and cognitive ability of the central nervous system (CNS). The existences of Nootropics, and their ability to change the normal brain function, alter the mental perception, mood and the individual state of consciousness date back to over 10,000 years ago starting with something as simple as the coffee plant. Our ancestors noted that certain plants, such as Coffee and Gingko Biloba enhanced their level of thinking and the general perception of reality. Fundamentally, the first evidence to support the use of Nootropics can be traced from the Chinese practitioners. They made extracts from plants such as Ginseng and Ginkgo Biloba, which were then included during the routine herbal tea preparation. These extracts created a state of mental alertness and focus and ability to work for longer hours, without feeling fatigue. That is why our commitment to our customers is to provide the best nootropics around!

The modern use of Nootropics has been traced back to 1960s, when a Romanian doctor named Dr. Corneliu Giurge developed Piracetam (Nootropil) as the first modern nootropic known by man in 1964. Additionally, he carried out intensive research and formulated essential features that constituted a nootropic. Since then, more advanced formula of other Nootropics have been produced and released to the market. In addition, intensive research has been made on other smart drugs such as Aniracetam and Oxiracetam. Majorly, these studies have focused on specific stimulatory aspects and levels of effectiveness; in essence, their ability to activate various brain tissues and the nervous system has been of immense concern. According to WebMD, clinical research has been carried out on the mechanism of action of these brain supplements, regarding their ability to synthesize new neurotransmitter chemicals in the human brain, enhance cognitive function, and their efficacy in preventing neurodegenerative diseases. Initially, modern research on the safety and the effectiveness of Nootropics were studied on rats and animals. Over time, this has changed, and willing human patients have been used. In conclusion, despite the numerous potential therapeutic benefits of Nootropics, the FDA does not approve their use as nutritional supplements for consumption and medication as more research is necessary to determine their safety, as well as efficacy.

Types of Nootropics

RACETAMS

Racetams are the most popular class of nootropic agents that help to enhance the brain (cognitive) function. Racetams are commonly referred to as Nootropics or smart drugs. All nootropic agents in this class have similar benefits and chemical structure. Racetams directly affect the acetylcholine neurotransmitter that facilitates communication in the brain synapses, affect glutamate (amino acid) which facilitates communication in neurons, and provide neuroprotective properties. Some mental functions affected by Racetams include attention span, concentration, mood, and general mental focus. All racemic compounds possess a central core that is commonly referred to as pyrrolidone nucleus. Since the initial discovery of Piracetam in 1963 by Corneliu E. Giurgea, a Romanian Chemist, other racetams have been developed. A total of 19 racemic supplements are currently available, and they are Piracetam, Aniracetam, Coluracetam, Oxiracetam, Phenylpiracetam, Pramiracetam, Phenotropil, Etiracetam, Brivaracetam, Dimiracetam, Imuracetam, Fasoracetam, Nebracetam, Levetiracetam, Nicoracetam, Rolziracetam, Nefiracetam, Rolipram, and Seletracetam. Scientific and clinical studies have shown that some racetams have therapeutic efficacy, but racetams have not been approved by the FDA within the U.S. and Canada for medical use and are only accessible as over-the-counter supplements. In a number of countries, most racetams have been approved for medical uses and are therefore prescription drugs. Recently, racetams use has increased rapidly as young individuals mainly students use them as a study aid to boost their memory.

CHOLINE NOOTROPICS

Cholinergic Nootropics are an essential nootropic supplements that have cognitive benefits and are also very effective in potentiation of the effects of various brain boosters. Within the brain, choline is vital (acts as a precursor to Acetylcholine) in the synthesis of acetylcholine neurotransmitter that maintains optimal brain function and neuron health. As such, choline affects memory formation, focus, and attention. The human body synthesizes a considerable proportion of the choline it requires from choline-containing foods. Some individuals may suffer from choline deficiency as a result of consuming foods with minimal choline levels, and, therefore, choline supplementation is necessary. In general, there are five distinct ways to include choline in your diet which include Dietary Choline, Alpha GPC, CDP-Choline, Lecithin, and Choline Bitartrate. Dietary choline can be found in high levels in dairy and meat products. Despite evidence from scientific and clinical trials supporting therapeutic effects of various cholinergic compounds, within the U.S. and Canada, they are not approved for medical use and are only available as over-the-counter supplements.

AMPAKINES

AMPAkines are known as the most potent class of the nootropic supplements, and they are named after the glutamatergic AMPA receptor found in the brain which they largely influence. AMPAkines are synthesized from Piracetam, and they mainly improve the functioning of the AMPA receptor that is essential in the memory formation and communication processes between various brain regions. AMPAkines also act as NDMA receptor agonists within the brain. AMPAkines were only developed recently and, therefore, have limited statistical evidence from scientific studies and currently there are no clinical trials conducted on AMPAkines. Based on the scientific studies, AMPAkines have been observed to improve learning, memory, attention span, and alertness. Sunifiram and Unifiram are the most common AMPAkine Nootropics.

VITAMIN B DERIVATIVES

Vitamin B Derivatives is a relatively small class, but is still a crucial category of Nootropics. Most B Vitamins, including Thiamine influence the levels of choline, dopamine, and glutamate within the brain and as such very effective in the treatment of degenerative cognitive conditions such as Alzheimer's. These nootropic agents are often used in the treatment of physical and mental fatigue as well as memory enhancement. The most common Vitamin B Derivative is Sulbutiamine, which is derived from Vitamin B1 (Thiamine). Thiamine-derived (Sulbutiamine was the first to be synthesized) Nootropics were first synthesized in Japan by Japanese scientists following extended studies into deficiencies of various important nutrients like Thiamine. The Japanese people were on a diet that was mainly limited to daily consumption of rice during the period post the World Wars. Rice does not contain some of the essential nutrients like Thiamine, and this led to low energy levels and constant fatigue in Japanese people. Sulbutiamine boosted the alertness of users and also cured the mental and physical fatigue among the Japanese people.

PEPTIDE NOOTROPICS

>Peptide Nootropics are relatively rare compared to other Nootropics accept for Noopept. Peptides are short amino-acids chains connected by peptide bonds, and they are naturally occurring biological molecules. Noopept was first synthesized in Russia where it has a widespread medical use as a prescription drug for certain psychological conditions such as memory or focus deficiency. Within the U.S., it is not approved for medical use and is strictly used as a dietary supplement. Peptides including Noopept directly influence acetylcholine and glutamate in a similar manner to racetams although Noopept is dubbed to be more potent than Piracetam by about 1000 times. The high potency is attributed to its considerably higher bioavailability (increases the rate of crossing blood-brain barrier) and to the fact that Noopept affects both Acetylcholine and Glutamate whereas the majority of the racetams only affect acetylcholine. Scientific and clinical studies have demonstrated that they enhance memory, learning, alertness, motivation, and mental energy.

NATURAL NOOTROPICS

This class of Nootropics comprises of any natural, herbal, or organic Nootropics. Natural Nootropics are any category of plant-derived compounds that have natural nootropic benefits mainly involving the improvement of brain function and health. In most cases, natural Nootropics have low efficacy compared to synthetic Nootropics and stacking is recommended to boost your results. The low efficacy can be attributed to the fact that natural Nootropics contain the ingredients in their naturally occurring state and, therefore, are absorbed relatively slowly compared to synthetically produced Nootropics. To achieve the same levels supplementation produced by synthetic Nootropics, you would be required to take large amounts of natural Nootropics. Some of the highly effective natural Nootropics comprise Vinpocetine, Huperzine-A, Bacopa Monneri, and Ginkgo Biloba. Natural Nootropics have proved to be very safe and cheaper compared to other Nootropic agents. This class of nootropic agents is highly recommended for beginners and intermediate nootropic users.