Medications used during surgery (Anesthesia)Interaction Rating:
Moderate Be cautious with this combination.Talk with your health provider.

Evening primrose oil might interact with medications used during surgery. One person who was taking evening primrose oil and other medications had a seizure during surgery. But there isn't enough information to know if evening primrose oil or the other medications caused the seizure. Be sure to tell your doctor what natural products you are taking before having surgery. To be on the safe side, you should stop taking evening primrose oil at least 2 weeks before surgery.

PhenothiazinesInteraction Rating:
Moderate Be cautious with this combination.Talk with your health provider.

Taking evening primrose oil with phenothiazines might increase the risk of having a seizure in some people.