In the late 19th century, Kwai Chang Caine was the orphaned son of an American man and a Chinese woman. He was raised in a Shaolin monastery, and was trained by the monks to be a Shaolin master. After becoming a master, due to a violent incident he had to flee China to escape legal prosecution, ending up in the western United States looking for his half-brother. Although it was his intention to escape notice, the demands of morality and the responsibility to use what he had been taught in the monastery to aid the innocent against injustice, forced him to come into the open from time to time to right a serious wrong—and then to move on in a further search for anonymity and security.

After many adventures, the television series ended and Kwai Chang Caine passed beyond the eyes of fictive history, outside of a 1986 TV movie starring Carradine and Brandon Lee in which Caine was forced to fight his hitherto unknown son.
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