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El Tigre is called upon by Jimmy Neutron along with SpongeBob SquarePants, Danny Phantom, Patrick Star, Timmy Turner, and Tak. They have to save the nicktoons world by going through mazes and are given HoverBoards to do so.

Professor Calamitous attacks all worlds again by using Fairy Gas to power up his army of evil toys. After SpongeBob SquarePants finds his way into the evil toy factory, SpongeBob finds Patrick Star whom he rescues and meets up with Danny Phantom, Timmy Turner, Jimmy Neutron , and Tak. While on their dangerous quest to stop the professor's evil plan the nicktoons rescued El Tigre, Jenny Wakeman, Zim, GIR, and Mr. Blik and faced evil toy copies of several of the heroes. After beating Calamitous they sent him to jail.