Presence of at least one of the risk factors: obesity (BMI > 28), osteoarthritis at other sites, knee effusion, family history of total joint replacement

Exclusion Criteria:

Women with childbearing potential

Secondary osteoarthritis

Treatment with intra-articular or systemic steroids

Inability to undergo MRI acquisition

Other protocol defined inclusion/exclusion criteria may apply.

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00371670

United States: Food and Drug AdministrationBelgium: Ministry of Social Affairs, Public Health and the EnvironmentCanada: Health CanadaGermany: Federal Institute for Drugs and Medical DevicesItaly: National Monitoring Centre for Clinical Trials - Ministry of Health