Contact points on the bicycle (handlebars, saddle, and pedals) are areas that can often lead to discomfort when riding long distances, or stringing multiple days together. To some extent there is a natural break-in period, for both your equipment and your body, and only way to work through this period is to put in the time and miles. I have had good luck with saddles in the past, but for the feet, I have always found myself drifting towards a quicker fix, as hot spots while riding has been an issue for me over the years.