Three Part Question

In [adult trauma patients presenting with hemorrhage or at high risk of hemorrhage], does [early treatment with IV tranexamic acid] [reduce rates of death and blood transfusion secondary to bleeding]?

Clinical Scenario

Adult trauma patient presenting with hemorrhage or at significant risk of hemorrhage. Can early administration of a 1 g loading dose of Tranexamic acid infused over 10 minutes followed by a transfusion of 1 g over 8 hours decrease rates of adverse events including further hemorrhage, blood transfusion and death?