Spotlight

A JACS communication by members of the Banerjee and Smith labs and collaborators reveals that adenosyltransferase uses entirely different chemical mechanisms for making and breaking the Co-C bond in vitamin B12 and that this cofactor conservation strategy is lost when a disease-causing mutation is present.

Spotlight

A JACS communication by members of the Banerjee and Smith labs and collaborators reveals that adenosyltransferase uses entirely different chemical mechanisms for making and breaking the Co-C bond in vitamin B12 and that this cofactor conservation strategy is lost when a disease-causing mutation is present.