..The rapid evolution of the human genome combined with marked environmental and cultural perturbation in the past two generations might lead to the uncovering of cryptic genetic variation that is a major source of disease susceptibility...

..Here, we explore the distributions of cis-acting and trans-acting factors and their relative contributions to expression of transcripts that exhibit two or more classes of abundance among individuals within populations...

A genome-wide gene expression signature of environmental geography in leukocytes of Moroccan Amazighs

Youssef IdaghdourNorth Carolina State University, Raleigh, North Carolina, United States of AmericaPLoS Genet 4:e1000052. 2008

..3-kilobase stretch of sequence. Evidence for gene flow among geographically distinct samples suggests that the mobility of hosts of A. caninum is an important contributing factor to the population structure of the parasite...

..Incorporating estimates of genetic relationships into study designs will facilitate genomic analysis of environmental plasticity by aiding the identification of major regulatory loci in natural populations...

Comparison of regional gene expression differences in the brains of the domestic dog and human

Erin KennerlyDepartment of Genetics, College of Agriculture and Life Sciences, North Carolina State University, Raleigh, NC 27695, USAHum Genomics 1:435-43. 2004

..This study lays the foundation for detailed analysis of the population structure of transcriptional variation as it relates to cognitive and neurological phenotypes in the domestic dog...

Association between nucleotide variation in Egfr and wing shape in Drosophila melanogaster

..Strikingly, while 25% of all genes differ between the two parents, 33% differ between both F1's and the parents, averaged across sexes. However, only 5% of genes show overdominance, suggesting that heterosis for expression is rare...

Use of regression methods to identify motifs that modulate germline transcription in Drosophila melanogaster

..Here we discuss the set of community-wide genetic and molecular resources, including panels of specific types of inbred lines and high density resequencing and SNP detection, that will facilitate such studies...

..Comparison of two strains of A. caninum from North Carolina and Maryland only identified a single gene, one of the members of the ASP family, that was differentially repressed upon serum stimulation...

TRF1 and TRF2 use different mechanisms to find telomeric DNA but share a novel mechanism to search for protein partners at telomeres

Jiangguo LinPhysics Department, North Carolina State University, Raleigh, NC 27695, USA, Department of Environmental and Occupational Health, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15219, USA, Electric and Computer Engineering Department, University of North Carolina at Charlotte, Charlotte, NC 28223, USA, Department of Industrial and System Engineering, North Carolina State University, Raleigh, NC 27695, USA, Department of Cell Biology, Center for Biologic Imaging, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15219, USA, Division of Biophysics, Universitat Osnabruck, Barbarstrasse 11, 49076, Osnabruck, Germany and School of Biological Sciences, University of Essex, Colchester, Essex CO4 3SQ UKNucleic Acids Res 42:2493-504. 2014

..This 'tag-team proofreading' represents a more general mechanism to ensure a specific set of proteins interact with each other on long repetitive specific DNA sequences without requiring external energy sources...

..Two new studies of genes that have experienced positive selection since the origin of pastoral agriculture help explain the incidence of lactose tolerance and diabetes, but cast considerable doubt on the popular thrifty genes hypothesis...