OBJECTIVE
To evaluate the efficacy of tranexamic acid in the treatment of idiopathic and non-functional heavy menstrual bleeding.
DESIGN
Systematic review.
POPULATION
Women with a diagnosis of idiopathic and non-functional heavy menstrual bleeding treated with tranexamic acid.
METHODS
Electronic searches were conducted in literature databases up to… (More)

The mechanism of antimalarial action of the ruthenium–chloroquine complex [RuCl2(CQ)]2 (1), previously shown by us to be active in vitro against CQ-resistant strains of Plasmodium falciparum and in vivo against P. berghei, has been investigated. The complex is rapidly hydrolyzed in aqueous solution to [RuCl(OH2)3(CQ)]2[Cl]2, which is probably the active… (More)