Background
The tumor suppressor pRb plays a key role regulating cell cycle arrest, and disturbances in the RB1 gene have been reported in different cancer forms. However, the literature reports contradictory findings with ...

N-terminal acetylation (N-Ac) is a highly abundant eukaryotic protein modification. Proteomics revealed a significant
increase in the occurrence of N-Ac from lower to higher eukaryotes, but evidence explaining the underlying ...

<p>Until recently CO2 has been utilized as an anesthetic method before gill cutting of
Norwegian Atlantic salmon farmed fish. From 1. July 2012 this is no longer permitted in
Norway since it causes strong aversive reactions ...

Cis-regulatory elements can control gene transcription over large distances. Studying the association between cis-regulatory elements and the mechanism of gene regulation is important since the disruption in the transcriptional ...

<p>Background: Joining a model for the molecular evolution of a protein family to the paleontological and geological records (geobiology), and then to the chemical structures of substrates, products, and protein folds, is ...

Neuroglobin (Ngb) exists only in small amounts in salmon brain. In order to study the
protein in more detail salmon neuroglobin (sNgb) was cloned, hetereologously
expressed in E.coli and purified. The protein had red ...

The packaging of DNA into nucleosomes is a fundamentally conserved property of
the eukaryotic nucleus which is evident in the conservation of histone sequences.
Nevertheless, it is now clear that histone sequence variants ...