Please try to disable all background programs in case these are interfering with the normal running of the game.
You can do this by running msconfig and disabling all non-windows start-up programs and services.
Then once you have disabled all non-Microsoft services, please run the game and see if the issue persists.
If it does not, please then reopen msconfig and reenable those services, one by one, until you find the program causing the problem.

Got the game gifted to me by a friend today so that we could play together, and getting the same problem.

Am I seriously expected to unplug my joystick, throttle, and rudder pedals just to be able to play a game with mouse and keyboard? It will screw up every single game I use those for since the device ID will change for the devices, meaning I have to mess with control configurations in every single flight simulator I touch, every time I've touched this game.

I guess I come off as a little hostile, but it increasingly common (even in AAA titles!) that the game auto-detects devices and chooses on its own what I'm supposed to use. What happened with getting to choose control devices like a human being?

Unfortunately this issue is more usual than you think and all the times I have experienced this was with AAA games like XCOM, Risen, etc.
I gave up of having my Saitek pedals and my Thrustmaster joystick plugged on the computer because of issues like these.
I've only have them plugged when I want to play the game I intend to use them.

Please also note that this won't happen with everyone who got a different type of control attached to their system.
I have just checked and I don't experience the issue with my other controllers plugged in.

Having said this, it doesn't means that the developer of Heroes of Normandy won't try to fix the issue.

@MarvinC
Can you please attach a DxDiag report file?
How to get a Directx Dialog file:

I just bought game and my Anker® Ergonomic Optical USB Wired Vertical Mouse 1000 / 1600 DPI, 5 Buttons CE100 works but is off by about 1 inch on the screen. Which means I have to click 1 inch off to the left of any button on the screen to make it work. Have any fixes for this please? Also tried just a regular HP Mouse and does the same thing. Very Very hard to play with trying to figure out where to click on the screen. thank you in advance for help.

When I start the game, I am able to navigate the first menu but once I select something such as campaign, the mouse begins to repeatedly snap back to the centre of the screen when I try to move it in order to select one of the three campaigns. I have found that in order to circumvent this, I have to hold down ALT and press PLAY GAME when I first boot up the title in order to bring up the input settings sub-menu. I have already remapped the default joystick axes over to my throttle but in order to prevent the mouse centering bug, I have to remap the controls over to the throttle each time.

Zak, as I mentioned earlier, I am not going to crawl around under my desk to unplug 3 USB devices each time I want to play this game and then have to go and plug them back in when I want to play a flight sim (which is my main gaming focus). I've had a few other games over the years that have also had a controller conflict but this is the exception, not the norm so obviously it can be corrected.

as of yet your the only one with a issue on it tbh, while others have other issues, none are the same as yours so unless the developer can replicate it, it will be hard to fix.

drivers and hardware conflicts aren't something that anyone can foresee or cater for, as not every device can be tested with, my advice to either update the software or unplug the device that causes the issue imo is still the best course of action i can think of for now, while the developers are busy fixing the next update for the cards being developed, sorry for this, but not a lot i can do.