Evidence Supporting Taxonomic Applicability

Regulatory Examples Using This Adverse Outcome

Cumulative fecundity is the most apical endpoint considered in the OECD 229 Fish Short Term Reproduction Assay. The OECD 229 assay serves as screening assay for endocrine disruption and associated reproductive impairment (OECD 2012). Fecundity is also an important apical endpoint in the Medaka Extended One Generation Reproduction Test (MEOGRT; OECD Test Guideline 240; OECD 2015).

A variety of fish life cycle tests also include cumulative fecundity as an endpoint (OECD 2008).