Mozobil

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Mozobil

DRUG DESCRIPTION

Mozobil (plerixafor injection) is a sterile,
preservative-free, clear, colorless to pale yellow, isotonic solution for
subcutaneous injection. Each mL of the sterile solution contains 20 mg of
plerixafor. Each single-use vial is filled to deliver 1.2 mL of the sterile
solution that contains 24 mg of plerixafor and 5.9 mg of sodium chloride in
Water for Injection adjusted to a pH of 6.0 to 7.5 with hydrochloric acid and
with sodium hydroxide, if required.

Plerixafor is a hematopoietic stem cell mobilizer with a
chemical name l, 1'-[1,4-phenylenebis (methylene)]-bis-1,4,8,11-
tetraazacyclotetradecane. It has the molecular formula C28H54N8
The molecular weight of plerixafor is 502.79 g/mol. The structural formula is
provided in Figure 1.

Figure 1: Structural Formula

Plerixafor is a white to off-white crystalline solid. It
is hygroscopic. Plerixafor has a typical melting point of 131.5 °C. The
partition coefficient of plerixafor between 1-octanol and pH 7 aqueous buffer
is < 0.1.

What are the possible side effects of plerixafor (Mozobil)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have a serious side effect such as: