Topic Contents

Scleroderma

Topic Overview

Scleroderma is a rare disease in which a person's immune system
begins to destroy normal, healthy tissues. (This is called an autoimmune disease.) As a result,
connective tissue of the skin, lungs, and internal organs—especially the
esophagus, kidneys, and digestive tract—is replaced with scar tissue. This
change causes the tissues to become stiff and the muscles to not work as
well.

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