RCBTB1 encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. Additionally we are shipping RCBTB1 Antibodies (68) and RCBTB1 Kits (2) and many more products for this protein.

Study identifies RCBTB1 as a modifier of the smoking effect on carotid intima-media thickness.

Data show that the biological actions of Clld7 are consistent with those of a tumor suppressor.

RCBTB1 Protein Profile

Protein Summary

This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies.