Derek Lowe (17-7) held Baltimore to two hits over six innings, and Jason Varitek, Nomar Garciaparra and Kevin Millar homered as Boston clinched the last spot in the AL playoffs with a 14-3 victory.

The Red Sox, who have made the postseason 10 times since 1918 without winning a championship, are four games ahead of the Seattle Mariners in the AL wild-card race with three games remaining.

Omar Daal (4-11) has not won since May 30, a span that includes two months on the disabled list with tendinitis on his left rotator cuff. He allowed seven runs and seven hits, getting just five outs.

Delgado connected in four straight at-bats. His first homer of the game was the 300th of his career. His fourth came off Lance Carter (7-5).

Delgado was the first player to homer four times in a game since Shawn Green did it for Los Angeles on May 23, 2002, against Milwaukee.

The Toronto slugger was the fifth AL player to do it, the first since Mike Cameron for Seattle on May 2, 2002, against the Chicago White Sox. Lou Gehrig, Rocky Colavito and Pat Seerey also did it in the AL.

Trever Miller (2-2) pitched 1 1-3 innings for the win.

With their third straight win, the Tigers would have to lose their final three games of the season to break the post-1900 record of 120 defeats by the 1962 New York Mets.

Detroit (41-118) set the AL record for losses on Monday night with its 10th consecutive setback. Since then, the Tigers have not lost.

Detroit has won three straight for the first time since sweeping a three-game series against Cleveland from Sept. 2-4.

Chris Mears (1-3) earned his first major league victory after pitching two innings of scoreless relief. Brad Thomas (0-1) took the loss.

With 101 runs scored and 41 stolen bases, Beltran is on the verge of becoming only the sixth player since 1900 to record 100 RBIs, 100 runs and 30 steals in a season.

Brian Anderson (14-11) took a no-hit bid into the fifth and beat the White Sox for the fifth time in six decisions. He went eight innings, gave up seven hits and three runs, with two walks and a strikeout.