CD 117

CD 117

Protooncogene that encodes the transmembrane tyrosine kinase receptor CD 117; detected by flow cytometry in most cases of acute myeloid leukemia, in small numbers of T- and B-lymphoblastic lymphomas, and in some gastrointestinal stromal tumors.

The diagnosis of seminoma was confirmed by further immunohistochemical studies (figure 2, C), although the negative staining for placental alkaline phosphatase and CD 117 are considered to be atypical for seminoma.

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