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The Cochrane Database of Systematic Reviews is considered the gold standard for
evidence-based medicine. Essential Evidence Plus includes the latest and most
up-to-date summaries of systematic reviews from the Cochrane Library, which are
the most rigorous and reliable evaluations of medical therapies available. You’ll
find summarized evaluations of the world’s best literature on the effectiveness of
therapy for 3,300+ clinical problems.

Alpha-glucosidase inhibitors for type 2 diabetes mellitusCochrane Systematic Reviews, 2-Nov-2008Alpha-glucosidase inhibitors such as acarbose or miglitol, have the potential to improve glycemic control in type 2 diabetes mellitus. The true value of these agents, especially in relation to diabetes related mortality and morbidity, has never been inves

Alprazolam for depressionCochrane Systematic Reviews, 21-May-2012The 'off-label' effect of alprazolam on depression has not been systematically evaluated.

Alprazolam for essential tremorCochrane Systematic Reviews, 27-Nov-2015Essential tremor (ET) is one of the most common movement disorders. Treatment is based primarily on pharmacological agents. On this basis, although primidone and propranolol are well-established treatments in clinical practice, they could be ineffective i

Altered dietary salt for preventing pre-eclampsia, and its complicationsCochrane Systematic Reviews, 18-Jan-2012In the past, women have been advised that lowering their salt intake might reduce their risk of developing pre-eclampsia. Although this practice has largely ceased, it remains important to assess the evidence about possible effects of altered dietary salt

Altered dietary salt intake for people with chronic kidney diseaseCochrane Systematic Reviews, 18-Feb-2015Salt intake shows great promise as a modifiable risk factor for reducing heart disease incidence and delaying kidney function decline in people with chronic kidney disease (CKD). However, a clear consensus of the benefits of reducing salt in people with C

Alternative versus conventional institutional settings for birthCochrane Systematic Reviews, 26-Jun-2012Alternative institutional settings have been established for the care of pregnant women who prefer little or no medical intervention. The settings may offer care throughout pregnancy and birth, or only during labour; they may be part of hospitals or frees

Alvimopan for recovery of bowel function after radical cystectomyCochrane Systematic Reviews, 2-May-2017Alvimopan is used in abdominal surgery to reduce postoperative ileus in patients undergoing small bowel resections with primary anastomosis. The role and efficacy of alvimopan in patients undergoing radical cystectomy with urinary diversion is not well un

Amantadine and rimantadine for influenza A in adultsCochrane Systematic Reviews, 7-Jun-2012Amantadine hydrochloride (amantadine) and rimantadine hydrochloride (rimantadine) have antiviral properties, but they are not widely used due to a lack of knowledge of their potential value and concerns about possible adverse effects.