I conclude that Epstein’s CCI may stimulate reform in calculus education, but, judging from the physics education reform effort, it may take several decades before widespread improvement occurs - see the review "The Impact of Concept Inventories On Physics Education and Its Relevance For Engineering Education" Hake (2011) at http://bit.ly/nmPY8F (8.7 MB).
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"Mathematics is the gate and key of the sciences. . . .Neglect of mathematics works injury to all knowledge, since he who is ignorant of it cannot know the other sciences or the things of this world. And what is worse, men who are thus ignorant are unable to perceive their own ignorance and so do not seek a remedy."
- Roger Bacon (Opus Majus, bk. 1, ch. 4) http://bit.ly/dzjbWv

REFERENCES
Hake, R.R. 2011. "The Impact of Concept Inventories On Physics Education and It's Relevance For Engineering Education," invited talk, 8 August, second annual NSF-sponsored "National Meeting on STEM Concept Inventories," Washington, D.C., online as an 8.7 MB pdf at http://bit.ly/nmPY8F or as ref. 64 at http://bit.ly/a6M5y0. The abstract and link are being transmitted to various discussion lists and are also on my blog "Hake'sEdStuff" at http://bit.ly/pYmIkP with a provision for comments.

Hake, R.R. 2013. "Can the Cognitive Impact of Calculus Courses be Enhanced?" An update of 26 Dec 2013 of an invited talk of 24 April 2012, Department of Mathematics, University of Southern California, online as a 2.7 MB pdf at http://bit.ly/1loHgC4 and as ref. 70 at http://bit.ly/a6M5y0.