The recommended treatment
duration for a first episode of unprovoked venous thromboembolism (VTE) is, at
a minimum, 3 months with extended anticoagulation favored for those who are not
at high risk for bleeding. However, the
optimal duration of anticoagulation therapy remains unknown.

The Prolonged Anticoagulation
Treatment for a First Episode of Idiopathic Pulmonary Embolism (PADIS-PE) study
examines this question but, most importantly, provides insights about patient outcomes after anticoagulation
treatment is discontinued