One especially notable response to Huckabee's tweet came from comedian Cameron Esposito. After calling out the former governor for his insensitivity toward the LGBT community, Esposito, who is a lesbian, announced she was donating to Trans Lifeline, a hotline that provides transgender people in crisis with help and support. She encouraged others to do the same.

"Turn a heartless joke into heartfelt action & donate to @Translifeline in Brandon Teena's memory. I am!" she wrote on Saturday night.