Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42103 individuals

Gut, 04/20/2012Dunlop MG et al.

Genotype data provide additional information that complements age, gender and FH as risk factors, but individualised genetic risk prediction is not currently feasible. Nonetheless, the modelling exercise suggests public health potential since it is possible to stratify the population into CRC risk categories, thereby informing targeted prevention and surveillance.