Testosterona E (testosterone enanthate)

Testosterone enanthate is an oil based injectable steroid, designed to release testosterone slowly from the injection site (depot). Once administered, serum concentrations of this hormone will rise for several days, and remain markedly elevated for approximately two weeks. It may actually take three weeks for the action of this drug to fully diminish. For medical purposes this is the most widely prescribed testosterone, used regularly to treat cases of hypogonadism and other disorders related to androgen deficiency. Since patients generally do not selfadminister such injections, a long acting steroid like this is a very welcome item. Therapy is clearly more comfortable in comparison to an ester like propionate, which requires a much more frequent dosage schedule. This product has also been researched as a possible male birth control options9. Regular injections will efficiently lower sperm production, a state that will be reversible when the drug is removed. With the current stigma surrounding steroids however, it is unlikely that such an idea would actually become an adopted practice.

Before using testosterone enanthate:
Some medical conditions may interact with testosterone enanthate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances (especially sesame oil)
if you have heart disease, heart failure, coronary artery disease, angina (chest pain), high cholesterol levels, swelling (edema), lung disease, or sleep apnea (long pauses in breathing while you sleep)
if you have diabetes, an enlarged prostate, kidney or liver disease, high blood calcium levels, or obesity
if you have a history of blood clots
Some MEDICINES MAY INTERACT with testosterone enanthate. Tell your health care provider if you are taking any other medicines, especially any of the following:
Carbamazepine, corticosteroids (eg, prednisone), macrolide immunosuppressants (eg, tacrolimus), or oxyphenbutazone because their actions and the risk of their side effects may be increased by testosterone enanthate
Anticoagulants (eg, warfarin), insulin, or oral hypoglycemics (eg, glyburide) because their side effects, including risk of bleeding, may be increased by testosterone enanthate
Propranolol because its effectiveness may be decreased by testosterone enanthate
This may not be a complete list of all interactions that may occur. Ask your health care provider if testosterone enanthate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Testosterone’s anabolic/androgenic effects are dependant upon the dose administered; usually the higher the dose, the better the results (1).
In a study done on Testosterone Enanthate, a dose as high as 600 mg’s produced better results in subjects compared to those who received lower doses. The most fat was lost and lean body mass, strength and size was gained by the group who used the highest dose (600 mg/week), when compared to any of the lower doses studied (2). In the same study, HDL cholesterol was lowered and some acne was experienced by the subjects. There was roughly a 15% gain in Lean Body Mass from 20 weeks of 600mgs/week of testosterone enanthate. HDL cholesterol was also lowered and the subjects experienced acne.
Overall, the most common effect reported by subjects using testosterone is gains in strength (3) and typically, testosterone is implicated in positive alterations in size, shape, and appearance of muscle (4).
Due to stimulation of the Androgen Receptors (AR), accelerated muscle gain, fat loss, increased muscle repair and growth is experienced by those using injectable testosterone (5),(6). Testosterone can also binds to the AR on fat cells; therefore, adipose (fat) tissue can be broken down more readily and new fat formation is prevented (7). It is thought, therefore, that many of testosterone’s effects are receptor mediated; although many effects are also non-receptor mediated.