To date my wife has been diagnosed with Fibromyalga, CFS & Bipolar. Recently she has started collapsing for no reason. Her legs just give way - in her words "turn to jelly", and she has began to drop things also for no reason.

The effect is only for a second or so, but enough time for her to be on the floor, or down the stair case etc.

Any thoughts?

Nb her mother had Myasthenia gravis. However nerve tests 7 years ago (when she was aged 32) showed no signs.

Hi,
Fibromyalgia is a condition with having pain at multiple areas usually bilaterally symmetrical.It does not have any pathological cause.CFS is chronic fatigue syndrome sometime it may be due to low iron,low calcium or other conditions.You wrote diagnosis of bipolar that is a psychiatric disorder requires antipsychiatric medications.As there is family history of myesthenia gravis so its advisable to see a doctor for assessment.You have not clarified that wether this happens with increasing duration of work or exercise fatigue because this jelly legs may be first symtoms of myesthenia and its always occur only after exercises or strenious work and its relieved with rest.Iron,calcium and multivitamin supplements as well as reassurance may imrove the symtoms.
Regards,

Hi,
Fibromyalgia is a condition with having pain at multiple areas usually bilaterally symmetrical.It does not have any pathological cause.CFS is chronic fatigue syndrome sometime it may be due to low iron,low calcium or other conditions.You wrote diagnosis of bipolar that is a psychiatric disorder requires antipsychiatric medications.As there is family history of myesthenia gravis so its advisable to see a doctor for assessment.You have not clarified that wether this happens with increasing duration of work or exercise fatigue because this jelly legs may be first symtoms of myesthenia and its always occur only after exercises or strenious work and its relieved with rest.Iron,calcium and multivitamin supplements as well as reassurance may imrove the symtoms.
Regards,

Recent blood tests had normal levels of calcium and iron, but low levels of Vit D. The local GP has her on a suppliment for that (started 2 weeks ago).

The jelly legs do not occur with any pattern, they can be at any time of day, from first getting out of bed, onwards. However once it has occured it is likely to reoccur on the same day is she does not immedietely rest.

The CFS and fibromyalgia are long term conditions which she has had for over 12 years, with periods of remission. She is active for around 5-6 hours per day, the rest is spent resting.

Recent blood tests had normal levels of calcium and iron, but low levels of Vit D. The local GP has her on a suppliment for that (started 2 weeks ago).

The jelly legs do not occur with any pattern, they can be at any time of day, from first getting out of bed, onwards. However once it has occured it is likely to reoccur on the same day is she does not immedietely rest.

The CFS and fibromyalgia are long term conditions which she has had for over 12 years, with periods of remission. She is active for around 5-6 hours per day, the rest is spent resting.

To date my wife has been diagnosed with Fibromyalga, CFS & Bipolar. Recently she has started collapsing for no reason. Her legs just give way - in her words "turn to jelly", and she has began to drop things also for no reason.

The effect is only for a second or so, but enough time for her to be on the floor, or down the stair case etc.

Any thoughts?

Nb her mother had Myasthenia gravis. However nerve tests 7 years ago (when she was aged 32) showed no signs.

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