Case Studies

Poorly Soluble Compounds

"Currently, between 70 and 90% of drug candidates in pipelines are believed to have low solubility. In fact, poor solubility problems is considered to be the leading challenge in drug development" - Chemical Engineering News 2010

Captisol® Solutions

Captisol® is a circular-shaped molecule with a hydrophilic exterior surface and hydrophilic interior cavity. The hydrophilic surface generates good water solubility and a relatively hydrophobic interior cavity provides a favorable environment for water insoluble drug molecules.