Left Behind follows Rayford Steele (Nicolas Cage) who is piloting a commercial airliner just hours after the Rapture when millions of people around the globe simply vanish. Thirty thousand feet over the Atlantic, Rayford is faced with a damaged plane, terrified passengers, and a desperate desire to get back to his family. On the ground, his daughter, Chloe Steele (Cassi Thomson) is among those left behind, forced to navigate a world of madness as she searches for her lost mother and brother.

The movie is based on the New York Times bestselling book series of the same name, co-authored by Jerry B. Jenkins and Tim LaHaye.