Most of the tablets contain disintegrating agent. Disintegrating agents facilitate the disintegration of the tablet in small particles in the gastrointestinal tract. Breaking of tablet' based on the swellability, adsorption of water or chemical reaction.

Glidants act as a flow promoter and reduce the friction between particles. It improves the flow properties of granules or powder through hopper to die. It is not deformed compression pressure of the tablet machine. Examples include talc, starch, magnesium stearate, calcium stearate, boric acid, sugar, lycopodium and sodium chloride.

These materials are used to reduce the adhesion of the tablet surface to dies and punches during the compression of tablets. The pressure of the machine deforms these materials. It reduces sticking, picking and chipping problems. Examples include paraffin, stearic acid, cocoa butter, soaps, starch derivatives.

Coloring agent:

Colours are selected from 'permitted' list and are added to promote elegance and also to mask differences in colour or speckling when either the drug or an additive is off white.

Pastel shades are commonly used as these shades help in achieving uniform colour distribution. Coloring materials or dyes are used in tablet formulation mainly for three purposes; disguising of off color drugs, product identification and production of more elegant products. Colours may be added either to the vehicle used for granulation or to the mixture of powders prior to granulation.

The first approach is known to give better results provided migration of dye to the top of granules along with solvent during drying does not occur. When wet granulation is not to be employed, lake dyes (dyes adsorbed on alumina or aluminium hydroxide) are recommended.

Fading of the colour on standing and exposure to light leading to mottling of tablets is the common problem with dyes. Examples include water soluble dyes and many other FD&C approved colors or dyes.

Flavoring agent:

These substances are not necessary for the formulation of compressed tablets. The proportion of flavours should generally be limited to 0.5% because excessive amounts may interfere with the free flow or cohesion of the granules.

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