Antipsychotic Use In Pregnancy Presents No Meaningful Risk to Newborns

Reuters (8/17, Seaman) reports that expectant mothers taking antipsychotics “can continue taking most of those medications without worrying the” medicines “will increase the risk of their newborns having birth defects,” researchers found in a study published online Aug. 17 in JAMA Psychiatry. Investigators arrived at the study’s conclusion after examining “data on over 1.36 million U.S. pregnant women enrolled between 2000 and 2010 in Medicaid.”

HealthDay (8/17, Preidt) reports, “The study focused on the most often used” medicines in both typical and atypical antipsychotic “classes: aripiprazole (Abilify), olanzapine (Zyprexa), quetiapine (Seroquel), risperidone (Risperdal) and ziprasidone (Geodon).” The study authors “reported birth defects in about 3.8 percent of babies born to women who had taken a typical antipsychotic and 4.45 percent whose mothers had taken atypical antipsychotics.” In comparison, “the birth defect rate of babies whose mothers had not taken an antipsychotic” were found to be “3.27 percent.”