Orocecal transit: Time of radioactive marker to reach the cecum using scintigraphy

Secondary Outcome Measures:

Whole gut transit and stomach emptying: Following 2 weeks of treatment, the rate of transit of food through the colon and stomach will be measured using scintigraphy

Estimated Enrollment:

60

Study Start Date:

July 2006

Study Completion Date:

April 2007

Eligibility

Ages Eligible for Study:

65 Years and older

Genders Eligible for Study:

Both

Criteria

Inclusion Criteria:

Male & Females aged 65 and older

Patients must meet the criteria for chronic idiopathic constipation for at least 12 weeks

Patients must have had a colonoscopy within the past 5 years

Patients must pass a balloon expulsion test at screening

Patients must be able to comply and understand the use of a diary

Exclusion Criteria:

Patients with a clinically significant medical condition that would interfere with the patient completing the trial

Patients with loose stools at least once per week

Patients with IBS

Known allergies to the same class of drug and/or allergies to eggs

Patients who require the use of manual maneuvers to have a bowel movement

Other protocol-defined inclusion/exclusion criteria may apply.

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00348634