Grants typically support large universities and medical research centers such as Harvard Medical School and Dana-Farber Cancer Institute. Amounts are often substantial, ranging from around $200,000 to upwards of $2 million. Awards are made for periods of one year and are renewable based on progress.

AMRF accepts unsolicited inquiries from researchers and investigators interested in joining the AMRF program as collaborating scientists. Submissions are accepted on a rolling basis throughout the year.