Ladies and gentlemen, meet the newest pop BFF power couple…Taylor Swift and Madonna!

The massively successful pop titans caused the biggest shock of the night by teaming up on stage for a somber, yet powerful performance of Madge’s new Rebel Heart single, “Ghosttown.” Later on, M returned the favor by awarding Taylor with the Artist Of The Year award. And by the looks of it, they’re pretty enamored with each other!

The two record-breaking superstars also took turns paying homage to each other off-stage too, with Madonna Instagramming her #RebelHeart away (“My new favorite guitar player! Thank you Taylor! Just you and I in a #ghostown”) while Taylor went shaking and crying over professional pics of their collaboration on Twitter. #MyFangirlLife!

Could this new friendship lead to a musical collaboration down the line?

Check out the gallery of these two ladies making music together up top, and leave your thoughts in the comments below.