The site was to be the defunct lender's new headquarters but was sold last year to the Central Bank.

Overnight, vandals gained access and painted ‘S Dunne', ‘Drumm', ‘US Fed Reserve' and other phrases across several floors of the concrete shell.

The graffiti is a reference to developer Sean Dunne, who borrowed huge sums from Anglo, and David Drumm, the lender's former chief executive. Gardai confirmed today they have been notified about the incident and are looking into the matter.

“We've had a few queries in relation to it. Store Street gardai are aware of it and are investigating. We heard about it this morning,” a spokesman told the Herald.

Some of the graffiti is anti-Semitic including ‘Jewish financial terrorism’.

The individual or individuals responsible managed to climb to the very top floor of the building.

Last year, NAMA reached an agreement with the Central Bank to sell the unfinished block to the Central Bank for €7m.