Glucotrol

DRUG DESCRIPTION

GLUCOTROL (glipizide) is an oral blood-glucose-lowering drug of the sulfonylurea class.

The Chemical Abstracts name of glipizide is l-cyclohexyl-3-[[p-[2-(5-methyrpyrazine-carboxamido)ethyl]phenyl]sulfonyl]urea.
The molecular formula is C21H27N5O4S;
the molecular weight is 445.55; the structural formula is shown below:

Glipizide is a whitish, odorless powder with a pKa of 5.9. It is insoluble in water and alcohols, but soluble in 0.1 NNaOH; it is freely soluble in dimethylformamide. GLUCOTROL (glipizide) tablets for oral use are available in 5 and 10 mg strengths.

What are the precautions when taking glipizide (Glucotrol)?

Before taking glipizide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar levels. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you...