This course familiarizes students with the novel concepts being used to revamp regulatory toxicology in response to a breakthrough National Research Council Report “Toxicity Testing in the 21st Century: A Vision and a Strategy.” We present the latest developments in the toxicology field: moving away from animal testing toward human relevant, high content, high throughput integrative testing strategies. Active programs from EPA, NIH and the scientific community work-wide illustrate the dynamics of safety sciences.

From the lesson

Module 3

This module will familiarize you with Human Toxome Project run by Johns Hopkins University in collaboration with several university, industry and research agencies.
Omics technologies their advantages and disadvantages as well as concepts of Adverse Outcome Pathway (AOP) and Pathway of Toxicity (PoT) will be discussed