Meigs demonstrated her interest in biography with her prize-winning biography of Louisa May Alcott, Invincible Louisa. Meigs also wrote a critical work about Alcott for adult readers, Louisa May Alcott and the American Family Story (1971), and edited a collection of Alcott's short stories, Glimpses of Louisa: A Centennial Sampling of the Best Short Stories by Louisa May Alcott.

Meigs's books about social history include Young Americans: How History Looked to Them While It Was in the Making (1936) and, for adult readers, The Violent Men: A Study of Human Relations in the First American Congress (1949) and The Great Design: Men and Events in the United Nations from 1945 to 1963 (1963).