It definitely is not a job to do 'on the road'.
I always remove the anode rod after camping season is over, and always use teflon tape on the threads when I reinstall it, so never have a problem. But I suppose for full-timers, it may be a job that seldom gets done. I imagine though, that if teflon tape had been used, it shouldn't have gotten stuck. I also never tighten the heck out of it, actually only snugging it up until it quits leaking.
From years of experience with pipe thread, some are impossible to break apart without getting them red hot with a blowtorch. That is not the best solution around flamable materials, such as camper parts!

Thanks to both of you. I'm on a trip so I may need to wait till I get home and get can get down to it. I had thought removing it was gonna be quick and easy

I carry a 1/2" drive torque wrench for the lug nuts and an old 1-1/16" socket strictly for the anode and change the anode on the road or while camping if I forget to do it at the start of our annual trips to FL. Did it last yr in Orlando, not really much of a job if you have the right tools and have nothing else to do.

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Days camped in 2015-45 as of 15Feb15
Days camped in 2014-114
2012 Flagstaff 8528RKWS towed w/ 2005 Silverado 1500 Ext. Cab
Camping since Aug1960
“Never argue with stupid people, they will drag you down to their level and then beat you with experience.” ― Mark Twain

Admittedly I never changed it in the 2 years I have owned it. I use it year roun so it doesn't get winterized buy who would this a new rig would be that bad in 2 years. I have work to do when I get home

I don't imagine the factory would bother putting anything on the threads to keep it from sticking, so two years is lots of time for the threads to rust and weld themselves together.
It is also good to drain the tank once in a while in case there is any solids collecting in the tank.
As always, more maintenance=less hassles down the road.

Thanks to both of you. I'm on a trip so I may need to wait till I get home and get can get down to it. I had thought removing it was gonna be quick and easy

It normally is a quick & easy job. Usually takes longer to drain the tank than to change the anode. I have even changed them while the tank is draining (of course the tank was cool) which is not that hard if you stand to the side so you don't get wet.

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__________________
Days camped in 2015-45 as of 15Feb15
Days camped in 2014-114
2012 Flagstaff 8528RKWS towed w/ 2005 Silverado 1500 Ext. Cab
Camping since Aug1960
“Never argue with stupid people, they will drag you down to their level and then beat you with experience.” ― Mark Twain