CLINICAL EFFECTS OF TRABECULECTOMY COMBINED WITH MECOBALAMIN IN TREATING LATE GLAUCOMA

Objective:To investigate the effects of trabeculectomy combined with mecobalamon in treating late glaucoma.Methods:46 patients with late glaucoma were treated by trabeculectomy.Adjustable suture was applied.All patients received mecobalamin therapy after operation for 3 to 6 months.Results:Mean intraocular pressure(IOP) before and after operation was 38.97±2.91mmHg,and 14.41±2.17mmHg.In terms of vision change 2 weeks after operation: 10 eyes(21.74%) improved by more than two lines,20 eyes(43.48%) improved by less than two lines,14 eyes(30.43%) showed no improvement,and 2 eyes(4.34%) decreased.All 46 patients were followed-up for 6 to 24 monthes,no loss of vision ever found.In terms of visual field after operation:8 eyes(17.39%) improved,34 eyes(73.91%) had no change,and 4 eyes(8.70%) worsened.Conclusion:For late glaucoma,trabeculectormy combined with neuroprotective agents can effectively control IOP and slow down the loss of visual function.