European comparative genetic resource

Dane projektu

Całkowity koszt:

Wkład UE:

Kraj koordynujący:

Topic(s):

System finansowania:

CSC - Cost-sharing contracts

Cel

At the end of 1996 two large scales ENU mouse mutagenesis projects were initiated in Europe.The goal of both screens is the production of mouse mutants wich will allow a better understanding of the molecular basis of such inherited diseases. So far, only a small percentage of the newly isolated mutations have been or are currently mapped be- cause of limited funding.Under the umbrella of EuroCOGENT,two projects (EuroComp and EuroGenet) will be launched to map a large number of mutant mouse lines.Modifier screens will be started to mimic complex diseases in man.In addition,databases will be developed and integrated and advanced genotyping and mutation detection methods will be developed. This will create a unique resource for the scientific community and pharmaceucital industry.Whilst these resources for creating and exploiting mouse mutants existing in Europe are so far unmatched world-wide,it appears necessary to ensure their consolidation and efficient utilisation.