screening of about 50 genes encoding proteins of the NMDA receptor complex, chosen according to their chromosomal localisation located in hotspots depicted by genome-wide screens in large population of autistic patients

Department of Children's and Adolescent Health, Public Health College of Harbin Medical UniversityHarbin, Heilongjiang, China

Center for Information in BioMedicine, Key laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of ChinaChengdu, Sichuan, China

Change in The Parenting Stress Index - Short Form, 36 items -magnitude of stress in the caregiver-child system.

Change in The Griffiths Scales of Mental Development: a standardized developmental test for children birth to 96 months.

Change in The Autism Diagnostic Observational Schedule, second edition: semi structured standardized observation that measures autism symptoms in social relatedness, communication, play and repetitive behaviors.