It opens a channel that selectively permeable to

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Unformatted text preview: to AMPA-Glu Receptor. it
opens a channel that selectively permeable to monovalent cations equally permeable. large inward sodium, smaller outward potassium, result is large inward current. current
spread, depolarize the cell through capacitance. the outward capacitance depolarize the cell. ↑ PNa + PK ↑ PK or ↑ PCl AmPA-Glur E I E E I
glycine
GABA glutamate trigger
zone + they (glycine and
GABA) increase
permeability to
potassium or
chloride. in K+:
have outward K+
movement. In Cl-,
have outward cl
movement, so cl is
moving in. inward
capacitance zone
hyperpolarize the
cell (increase
difference between
inside and
outside). way of thinking:
1. some current will leak out. current travel through
path of least resistance. there's less current available
to depolarize the membrane.
2. calculate the membrane potential (goldman). if left
membrane is permeable to both potassium and
sodium, membrane potential is halfway between Eca
and Ena which is way to depol...
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