Background. Myeloid derived cell populations such as macrophages play a critical role in the early innate immune response, whilst dendritic cells are essential in bridging the progression to an adaptive immune response.

We invite applications for a British Skin Foundation-funded PhD studentship to investigate the role of eosinophils in skin inflammation and cancer development in the laboratory of Dr Jessica Strid ([email protected]).

A characteristic feature of chronic inflammatory reactions is their persistence and predilection for certain sites. Our group investigates the role that tissue resident stromal cells (fibroblasts) play in determining both the switch to persistence as well as the site at which inflammation occurs.

Employing a range of approaches to address the physiological importance of the circadian:nuclear receptor system, ranging from population genetics, experimental medicine studies, CRISPR engineered mice, and cell biology.

Chronic inflammatory diseases (CIDs) are a common group of highly disabling immune conditions leading to persistent inflammation and tissue-specific manifestations, such as ulcerative colitis and arthritis.

As we age, the systems of our bodies become less able to function; rendering people increasingly infirm. Ageing affects our immune system, impeding our ability to both fight infection and maintain tolerance.

The gut contains more nerves than any other part of the body outside the brain. These nerves contribute to pain responses and essential muscle movement, but their role during inflammation is not known.