Exosomes in the CNS

Audience: AdultsInformation: Extracellular vesicles have experienced increasing attention in recent years, as our understanding of the diversity of their function has expanded from simple waste disposal units to critical players in cellular communication. In the brain, exosomes have been shown to convey signals between neurons and glia, influencing synapse biology, and may contribute to disease by modulating spread of alpha-synuclein and tau. This symposium will explore the role of extracellular vesicles in pathological processes underlying neurodegenerative disorders, and the appeal of exosomes as biomarkers and targets for the development of novel therapeutics.