HAE is a genetic disease affecting between 6,000-15,000 people in the United States. It is characterized by sudden, severe, and painful swelling that can affect any part of the body, including the extremities, face, gastrointestinal tract, urogenital tract and – most dangerously – the tongue or larynx. Patients with HAE can experience frequent recurrences that can each last for a few days, with up to 100 days of incapacitation per year, making it challenging to excel in school and at work, and even participate in daily activities. Due to the rarity and lack of awareness of HAE, and symptoms that can mimic other conditions, such as an allergic reaction, HAE is commonly misdiagnosed. For some patients, it has taken up to 20 years and visits to a variety of physicians to reach the right diagnosis.

"One-third of undiagnosed HAE patients have undergone exploratory surgery during an abdominal attack, and 70-80 percent of HAE patients experience recurrent abdominal symptoms. These statistics underscore the importance of educational programs to raise awareness of the disease," said William J. Tremaine, M.D., AGA program advisor and Professor of Medicine at the Mayo Clinic. "Our hope is that, by collaborating on this innovative program, we can help educate gastroenterologists to work with allergists and immunologists to improve the rate of accurate and timely diagnosis of HAE and, therefore, patient care."

"This is an exciting partnership, bringing together two specialties to work towards relieving patient suffering," said Sami Bahna, M.D., DrPH, Chief of Allergy and Immunology at Louisiana State University Health Sciences Center in Shreveport, and President of ACAAI. "While allergists and immunologists are experts in the diagnosis and treatment of HAE, they truly need the support and dialogue with general practitioners, emergency medicine physicians, gastroenterologists, and other specialists to ensure HAE patients are getting appropriate treatment."

"With new, approved treatment options available, there is more reason than ever for doctors to know about HAE," said Dr. Jonathan Bernstein, ACAAI program advisor and Professor of Medicine, Department of Internal Medicine, Division of Immunology/Allergy at the University of Cincinnati.

ABOUT "HAE: LEARN ABOUT IT, TALK ABOUT IT"

The core component of "HAE: Learn About It, Talk About It" is an informational and interactive Web site – www.LetsTalkHAE.com – which provides physicians with the tools they need to more readily diagnose symptoms and treat HAE appropriately, including a diagnostic checklist and case studies. A Webinar on Thursday, June 3, presented by Dr. Jonathan Bernstein and Dr. William Tremaine, will provide physicians with an opportunity to learn more about identifying, diagnosing, and treating HAE. For more information, including how to register for the Webinar, visit www.LetsTalkHAE.com/webinar.

"HAE: Learn About It, Talk About It"is a joint effort of the American College of Asthma, Allergy and Immunology (ACAAI) and the American Gastroenterological Association (AGA) Institute and supported by ViroPharma Incorporated. Because the effects of HAE on patients and the medical community are significant, with attacks often mistaken by both physicians and patients for serious allergic reactions or abdominal surgical emergencies, "HAE: Learn About It, Talk About It" will be expanded in the coming months to include other medical specialties that may come into contact with patients with HAE.

About ACAAI

The ACAAI is a professional medical organization headquartered in Arlington Heights, Ill., that promotes excellence in the practice of the subspecialty of allergy and immunology. The College, comprising more than 5,000 allergists-immunologists and related health care professionals, fosters a culture of collaboration and congeniality in which its members work together and with others toward the common goals of patient care, education, advocacy and research. To learn more about allergies and asthma and to find an allergist, visit www.AllergyAndAsthmaRelief.org.

About the AGA Institute

The American Gastroenterological Association is the trusted voice of the GI community. Founded in 1897, the AGA has grown to include 17,000 members from around the globe who are involved in all aspects of the science, practice and advancement of gastroenterology. The AGA Institute administers the practice, research and educational programs of the organization. www.gastro.org.

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