Hector Santiago

The White Sox lost their fourth in a row, 7-2 on Tuesday, thanks to a three-run fourth inning and a four-run sixth inning from the Twins on “Dog Night” at Guaranteed Rate Field.

Kennys Vargas’ two-run home run highlighted the Twins’ three-run third, which came a half-inning after Tyler Saladino and Jose Abreu had RBI singles against former Sox Hector Santiago for a brief 2-0 lead.

The Twins had six hits against two Sox pitchers in the sixth inning in front of the announced crowd of 14,498 plus 463 canines.

At the plate: The White Sox managed just four hits.

On the mound: Mike Pelfrey allowed three runs, five hits, a walk and struck...

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