Facilities and Resources

The Saint Louis University Department of Biochemistry and Molecular Biology maintains
a number of facilities and resources for use by researchers.

Protein Core Facility

A shared-use facility that supports expression, purification and analysis of research
proteins by providing an array of instrumentation and consultation on strategies for
protein production from small to large scale. The facility is managed by Dave Wood,
Ph.D. Contact him at 314-977-9220 or dwood12@slu.edu.

Genomics Core Facility

This full-service facility provides investigators with a variety of options for whole
genome analysis via microarrays, high-throughput screening, immunoprecipitation and
sequencing strategies. The facility is managed by Dale Dorsett, Ph.D., who you can
contact at 314-977-9218 or dorsettd@slu.edu, and Kathie Mihindukulasuriya, Ph.D.,
who you can contact at 314-977-9252 or kkunz1@slu.edu.

High-Performance Computing

The Department of Biochemistry and Molecular Biology maintains a wide variety of computing
resources. These range from network and backup services to state-of-the-art high-performance
computing. The most recent addition to the department is the Gemini Computing Cluster that leverages modern technologies such as GPU computing capabilities. The cluster
consists of 344 CPU cores, 80 GPUs and 1.3 TB of aggregate RAM, providing 135 TFLOPs
peak computing power.

Other Facilities and Resources

Animal Care Facility

The 44,000-square-foot Animal Care Facility operated by SLU’s Department of Comparative
Medicine has three full-time veterinarians and offers training, colony health surveillance
and technical support, as well as consultation and collaborative services.

Animal Imaging Core Facility

Flow Cytometry Research Core

SLU’s Flow Cytometry Research Core offers a FACS Callibur flow-cytometer with cell
sorter, Biosciences LSR II, capable of 10-color analyses and Biosciences FACSAria,
with simultaneous sorting of four populations. It has two full-time staff members
and offers discounted rates to SLU researchers.

Lipidomics Core Facility

The Lipidomics Core Facility, operated by the department and the Center for Cardiovascular
Research at Saint Louis University School of Medicine, is a University resource located
in the Doisy Research Center. The facility focuses on small molecule identification
and quantification by mass spectrometry.

Instrumentation in this core includes a Thermo Electron Surveyor LC and Quantum Ultra
triple quadrupole electrospray ionization mass spectrometer, as well as two HP6890
gas chromatographs with FID detector and HP 5973 MS detector with both electron impact
and chemical ionization sources.The facility is managed by Dave Ford, Ph.D. Contact
him at 314-977-9264 or fordda@slu.edu.

NMR Facility

The Saint Louis University Department of Chemistry houses an NMR facility, which is
available to all researchers at SLU. The facility has a multinuclear Bruker spectrometer
with the field strength of 16.4 Tesla, as well as a newly-installed Bruker Avance
HDTM 700MHz NMR spectrometer. These instruments can be used to determine the structures
of organic molecules and biomolecules, and can also be used in other dynamic studies.

The facility is located in Shannon Hall and is managed by the Department of Chemistry.

Research Microscopy and Histology Core

Offered by SLU’s Department of Pathology, the Research Microscopy and Histology Core
provides a wide range of histological and microscopy services on a fee-for-service
basis.