La Crosse EncephalitisOur research primarily focuses on domestic mosquito-borne diseases in the western
North Carolina region. We use an eco-epidemiological approach to current and emerging
issues. Specifically, our principle research activities focus on La Crosse Encephalitis. This viral disease is responsible for the majority
of human mosquito-borne disease in NC and is found predominately in the western counties.
We have developed a strong collaboration with Dr. Gideon Wasserberg (UNC-Greensboro) to address fundamental questions of how human behaviors (e.g., anthropogenic
impacts) increase the risk of exposure to La Crosse virus in western NC.

TaxonomyWe also investigate unresolved taxonomic questions within the Culicidae using both
molecular and morphological approaches. Additional studies involve the use of molecular
techniques to validate morphological characters to distinguish mosquitoes that are
often difficult to identify by microscopy. Using DNA sequencing, we (Harrison et al)
have validated a novel morphological character to separate the adult females of Aedes (Ochlerotatus) atlanticus and Aedes (Ochlerotatus) tormentor. Additional studies are underway validating morphological characters to identify
field collected Culex pipiens and Culex restuans.

Invasive SpeciesIn addition, we also collaborate with Dr. George O’Meara (University of Florida) investigating
the impact of an invasive mosquito species (Aedes japonicus) from Southeast Asia on our native rock pool mosquito (Aedes atropalpus) populations. Our studies on the impact of this invasive mosquito species have demonstrated
the dynamic nature of mosquito-borne disease ecology. This mosquito is now found in
high abundance in western NC and has likely displaced a native mosquito species. The
public health implications of this invasion are profound because the invasive species
is known to be capable of transmitting La Crosse virus.