SQL Server 2008 Reporting Services internal error

Recieved this error and wondering if anyone has an insight into a solution:

An internal error occurred on the report server. See the error log for more details. (rsInternalError) Get Online Help Could not load file or assembly 'Microsoft.ReportingServices.RdlObjectModel, Version=10.0.0.0, Culture=neutral, PublicKeyToken=89845dcd8080cc91' or one of its dependencies. Access is denied.

Definitely ensure your SSRS account is adequate privileges, but you may also need to take a look at the web layer authentication. See here:
http://social.msdn.microsoft.com/Forums/en/sqlreportingservices/thread/db19c566-f876-4fb1-8bd2-f73449ae3531

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