Psychiatric Genomics Consortium Schizophrenia Datasets

The Psychiatric Genomics Consortium (PGC) sent their full sample schizophrenia GWAS results,
individual quality controlled genotypes, and individual level dosage data (from an imputation model) for a
subset of the full sample (i.e., "deposited data") to the NIMH Repository for distribution to qualified
investigators. The PGC was founded in 2007 to conduct meta-analyses of genome wide data on psychiatric
disorders. A major goal of the PGC is sharing data with the international scientific community. More
information on the PGC may be found at their website (https://www.med.unc.edu/pgc).

PGC Schizophrenia Datasets

The PGC sent summary statistics for the full schizophrenia sample, n=22,127. In addition, subject-level data
(original and imputed dosage genotypes) is provided for a subset of n=15,691 individuals, which excludes
subjects from four samples (studies) due to restrictions on data sharing (see Table). The dosage genotype data
is the result of an imputation model where fully observed snps are coded 0, 1, 2 and imputed snps have a single
dosage on the interval [0,2]. The studies in the PGC that also have blood samples and/or phenotype data in the
NIMH Repository are CATIE and MGS. Files available for download by authorized users include plots (Manhattan
and QQ), a list of the top 1,000 SNPs, PLINK files of genotype data for individual datasets, and imputed dosage
data for 2.4 M SNPs.