The Trojans defeated lowly Washington State 69-0 in what was rout from the outset. Mark Sanchez broke a school record by throwing five touchdown passes in the first half. USC had three running backs with over 100 yards in the game as Broderick Green led the way with 121 yards on 18 carries with two touchdowns, Stafon Johnson had 112 yards on 11 carries and C.J. Gable added 109 yards and three touchdowns on 16 carries.

The Trojan defense gave up only 28 passing yards to the Cougars and 116 total yards on the contest while its offense put up 625 yards of total offense.