For decades, researchers have struggled with the conundrum of how to exploit the antidepressant effects of ketamine without incurring its psychedelic effects. Now, a group from NIH and the University of Maryland has shown that...

A pair of preclinical studies published last month on the autism target SHANK3 provide what might be the most meaningful progress for patients since the gene was linked with the disease over a decade ago....

Although Merck Serono S.A. decided to drop Parkinson's disease from its neuroscience portfolio, its preclinical compounds targeting metabotropic glutamate receptors for PD will continue to live on in a newco called Prexton Therapeutics S.A.
Backed by...

Studies by two American teams have converged on a family of metabotropic glutamate receptors as players in attention deficit hyperactivity disorder and autism spectrum disorder.1,2 The findings build an argument for agonizing the receptors in...

Addex plans to restructure and reduce headcount by about 25% to reduce costs. The company expects the changes to produce annual savings of CHF8 million ($9.4 million) and extend the company's cash through the end...