In patients who have previously undergone coronary artery bypass graft surgery (CABG), surgical aortic valve replacement (SAVR) can be a complicated procedure due to the risks of sternal re-entry and cardiac or graft injury. Transcatheter aortic valve replacement (TAVR) offers a less invasive approach that may be more optimal...

Association Between Preoperative Opioid and Benzodiazepine Prescription Patterns and Mortality After Noncardiac Surgery
Strategies to amend clinician prescription patterns are of critical importance in addressing opioid abuse and opioid-related deaths across the United States. One potential approach involves targeting opioid-prescription practices in the perioperative period. However, little is known about...

1. In this retrospective cohort study, the rate of 30-day post-procedure stroke after transcatheter aortic valve replacement (TAVR) remained stable during the first five years of US clinical practice.
2. 30-day stroke rates were similar between patients who received dual antiplatelet therapy, oral anticoagulants, or neither at hospital discharge.
Evidence Rating...

1. Among patients with severe aortic stenosis at low-risk for surgery, transcatheter aortic valve replacement (TAVR) with a self-expanding valve was noninferior to surgical aortic valve replacement (SAVR) with respect to a composite of all-cause mortality or disabling stroke at 24 months.
2. While all-cause mortality was similar between TAVR...

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