Background*

Dr. Una S. Ryan, O.B.E., Ph.D. serves as a Managing Director at Golden Seeds LLC. Dr. Ryan is a Partner at Astia Angel. She served as the President and Chief Executive Officer at Waltham Technologies, Inc. She served as the Chief Executive Officer of AVANT Immunotherapeutics Inc. since August 1996 and President since May 1996. Dr. Ryan served as the Chief Operating Officer of AVANT Immunotherapeutics Inc. from May 1996 to March 2005. She joined AVANT Immunotherapeutics ... Inc. as Vice President, Research and Chief Scientific Officer in May 1993. She served as President and Chief Executive Officer of Diagnostics For All (DFA). She served as Chief Executive Officer and President of Medarex, Inc. until July 2008. Dr. Ryan served as director of health sciences at Monsanto Corporation. She served as Chief Executive Officer and President of Celldex Therapeutics Inc. from August 1996 to May 7, 2008 and served as its Chief Operating Officer since August 1996. Dr. Ryan served as Director for Health Sciences of Monsanto Company from January 1990 to November 1992 and Research Professor of Surgery, Medicine and Cell Biology at Washington University School of Medicine from 1990 to 1994. She serves as the Chairman of The Bay Area BioEconomy Initiative. She serves as Director of Management Sciences For Health, Inc., and RenovoRx, Inc. She serves as a Director of Bioarry Therapeutics, BayBio, and Bell Biosystems. Dr. Ryan serves as a Member of Senior Advisory Board at Cellanyx Diagnostics, Inc. She has been a Director of Albany Molecular Research Inc., since October 31, 2006 and served as its Lead Independent Director. She served as a Director of IQuum, Inc. She was Chair of MassBio, New England Healthcare Institute, Board of Associates of the Whitehead Institute, Strategy & Policy Council of the MIT Center for Biomedical Innovation, the Massachusetts Life Sciences Collaborative Leadership Council and Management Science for Health. She served as Director of Biotechnology Industry Organization. She served as Director of Celldex Therapeutics, Inc. from May 1996 to May 2008. She served as a Director of AVANT Immunotherapeutics Inc., since May 1996. She served as Member of Scientific Advisory Board of Genocea Biosciences, Inc. Dr. Ryan served as a Senior Scientist at the Papanicalou Cancer Research Institute in Miami, and Director of the Laboratory for Ultrastructure Studies at the Howard Hughes Medical Institute. In 2006 former Massachusetts Governor Romney appointed Dr. Ryan to the Robert H. Goddard Council on science, technology, engineering and mathematics education. She is also Research Professor of Medicine at the Whitaker Cardiovascular Institute of the Boston University School of Medicine. In 2002, she was awarded the Order of the British Empire for her work to foster and promote biotechnology. In 2007, she was honored as a recipient of the Albert Einstein Award for outstanding achievement in the life sciences and professor of medicine at the University of Miami School of Medicine, 1972 to 1989. In 2002, she was awarded the Order of the British Empire for her work to foster and promote biotechnology. Dr. Ryan has over 35 years of experience as a Researcher, Professor and Biotechnology Industry Executive. Dr. Ryan holds a PhD in Cellular and Molecular Biology from Cambridge University and BS degrees in Zoology, Microbiology, and Chemistry from Bristol University. She received an Honorary Doctor of Science degree from Bristol University in 2009.

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