This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.

Catalog #

126504

Applications

Suitable for use in Immunofluorescence and Western Blot. Other applications not tested.

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Clone Type

Polyclonal

Isotype

IgG

Host

Mouse

Source

Human

Concentration

As reported

Form

Supplied as a liquid in PBS, pH 7.2.

Purity

Purified by Protein A affinity chromatography.

Immunogen

Full length human EXOSC1, aa1-196 (AAH22067).

Specificity

Recognizes human EXOSC1.

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.