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Moxi Flow

White Labs, in a collaboration with ORFLO Technologies, an innovator of cell analysis and flow cytometry solutions in the life sciences markets, is offering breweries and wineries a method for significantly improving their yeast counting and viability procedures.

The Moxi Flow combines high-powered traditional flow cytometry fluorescence detection with the Coulter Principle, and utilizes a patent-protected disposable flow cassette to process the yeast sample, to enable accurate cell counting assays within seconds. This is enabled through the use of a proprietary brewer's yeast application onboard ORFLO’s Moxi Flow, making it easier than ever to count brewers yeast. The Moxi Flow directly calculates the volume of 30-50,000 cells in 8 seconds along with simultaneously enabling fluorescence detection of a specific marker of interest, including Propidium Iodide for viability measurements. Because the Moxi Flow deploys the Coulter Principle it delivers direct gold standard accuracy and precision when calculating a stained (positive) cell from an unstained cell (negative) which eliminates rework and cost associated with poor experimental results, low fermentation performance due to improper count and viability inputs. It also saves hours of tune associated with manual cell counts. Unique to only the Moxi Flow, challenges with cell clusters are also eliminated with a tailored algorithm that accurately assesses the number of cells in a group, so flocculent yeast strains and budding yeast are no problem for the Moxi Flow. The technology of the Moxi Flow Smart Flow is quick, repeatable, and reliable.

By leveraging the advantages of a disposable cassette for samples, the Moxi Flow runs with a brand new flow cell for every experiment. This means no clogging, no rinsing, no cleaning, and no sheath fluids. Moxi Flow is also the only flow cytometer in the world that auto-aligns itself for every test. This means no annual service contracts, no down time, and no maintenance. By eliminating the parts and complexity of traditional flow cytometers, the Moxi Flow was miniaturized to enable in-hood use, and is ideal for remote, in-field test settings.

The Moxi Flow is a sub-$10K system and the per-test cost is $2.45. The architecture of the Moxi Flow makes it uniquely suited for the brewing industry because the programming has been developed by ORFLO Technologies, using direct input from White Labs and brewers in the industry.