Parkinson's disease (PD) is a neurodegenerative disease diagnosed by the presence of various motor symptoms, which result from loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). In addition to these ...

Cardiac aging is an intrinsic process that results in impaired cardiac function and dysregulation of cellular and molecular quality control mechanisms. These effects are evident in the decline of diastolic function, increase ...

Sleep apnea is a respiratory disorder characterized by periods of sleep during which no effective breaths are taken. Recurrent episodes of apnea caused by upper airway obstruction and/or cessation of central respiratory ...

The hope of dramatically extending our lifespan has captivated humanity for millennia. Over the last two decades, the biology of aging has matured as a field of study and led to greater engagement and investment in aging ...

In utero exposure to diesel exhaust air pollution has been associated with increased adult susceptibility to heart failure in mice but the mechanisms by which this exposure promotes susceptibility are poorly understood. ...