Walkthrough

Parsons State Insane Asylum is under attack and
Jack Cabot asks you to help him suppress it. You may follow along with him on his journey to the Asylum learning some interesting back story on the way or you may meet him outside the main entrance to find a
Raider onslaught. Enter with Jack and remove the enemies from existence. Unchain the door at Jack's office and go in.

Raiders have reached the basement, keep progressing through with Jack into the asylum. Go down the portion of floor that has collapsed. Go to a hole behind the wallpapered wall and drop down. Find the elevator and take it to the basement.

Follow Jack into the basement lab where Raiders are attempting to free
Lorenzo Cabot. Go through the doors, eliminating Raiders along the way. Loot the body of
Lefty to obtain
Mysterious Serum 4x. Jack will ask you to access the generators on each of the walls, and set 2 to manual override. Lorenzo is begging to be freed.

If you opt to keep Lorenzo locked up, set the last 2 generators to manual override so that Jack can flood the chamber with Zeta radiation and speak to Jack. He will thank you and reward you. Return to the Cabot House in one week and he will give you the unique weapon
Lorenzo's Artifact Gun. He will only give you this if you are polite to him during the entire quest.

If you free Lorenzo, he will escape and tell you he is going back to the Cabot House with murder on his mind. You can opt to warn the family of his return and help them defeat him. A week later return to Cabot House to receive the
Lorenzo's Artifact Gun. If you opt to aid Lorenzo in the murder, Lorenzo rewards you with the
Mysterious Serum.