ALPHA-GPC 100g

Alpha GPC is a natural cholinergic that has cognitive enhancing and neuroprotective properties.

CAS Number

28319-77-9

PubChem CID

657272

ChemSpider

571409

ChEBI

CHEBI:55397

ChEMBL

ChEMBL1567463

ECHA InfoCard

100.044.496

Chemical and physical data

Formula

C8H20NO6P

Molar mass

257.221 g/mol g·mol−1

What Is Alpha GPC?

Alpha GPC is the common name for L-Alpha glycerylphosphorylcholine, a cholinergic nootropic that occurs naturally but can also be taken as a supplement.Alpha GPC is best known for quickly and reliably delivering choline to the brain for the creation of the cognition-boosting neurotransmitter acetylcholine.

It has powerful benefits for both brain and body and may enhance the full range of cognitive functions, promote cellular health, and help maintain essential neurochemical balance in the brain.‍[1]

Alpha GPC is naturally present in the body in small amounts, and it is also commercially manufactured as a supplement using purified soy lecithin.

Though there are a few dietary sources of alpha GPC (most notably, dairy products, organ meats, and wheat germ), studies show that it only becomes pharmacologically active at high concentrations that are only attainable via supplementation.

Alpha GPC is available without a prescription as a dietary supplement in the US and Canada. In some European countries, it is regulated as a prescription drug and used for the treatment of Alzheimer’s disease.

Benefits and Effects of Alpha GPC

Alpha GPC is well known for its positive physical and mental effects, both when taken alone and in combination with other nootropics. Though many of its benefits are cognition-oriented and related to its cholinergic properties, it has also been shown to promote physical health and muscular strength.

Improved Memory and Enhanced Cognition

Alpha GPC’s ability to increase choline levels makes it an effective cognition enhancer, facilitating production of the neurotransmitter acetylcholine.

This capability makes it of particular value in the treatment of memory loss and cognition deficits related to neurological disorders.

Extensive clinical trials involving thousands of participants have shown it to be an effective treatment for memory loss associated with a variety of age-related disorders, including Alzheimer’s disease, vascular dementia, and stroke.

In Russia and some European countries, it is available as an oral or injectable prescription treatment for Alzheimer’s, sold under the brand names Gliatilin and Delecit and used to enhance memory, improve cognitive function, and help restore and maintain biochemical balance in the brain.

It is also prescribed to treat memory loss and cognition impairment related to stroke, traumatic brain injury, and dementia.‍

Though most research has focused on age-related memory loss, alpha GPC’s memory benefits don’t seem to be limited to the elderly. In a study involving 32 healthy young volunteers, alpha GPC effectively restored memory following temporary chemically-induced amnesia.‍

Anecdotal experience reports affirm that alpha GPC is an effective nootropic that provides a powerful cognitive boost, along with increased energy and motivation.

Neuroprotectant

Alpha GPC has been shown to protect and support overall brain health by encouraging the development of new brain cells and enhancing the body’s ability to repair damaged cell membranes.

Research using animal models of vascular dementia show that alpha GPC had a measurable neuroprotective effect.

Other studies indicate it may also have neuroprotective anti-aging capabilities.‍

Increased Strength and Rapid Post-Workout Recovery

Alpha GPC’s ability to stimulate the production human growth hormone has not been extensively studied, but some believe it may improve capacity to build lean muscle mass and recover more quickly after a workout.

A pilot study indicated that a 600 mg dose of alpha GPC, taken 90 minutes before bench pressing, increased power by 14%.‍

Another small study involving eight healthy young men under 25 showed that a single dose of alpha GPC increased growth hormone secretion and hepatic fat oxidation, both of which are associated with increased energy and reduced recovery time.

How It Works

Alpha GPC’s mechanisms of action have been extensively studied and are well understood, though the manner in which it affects some neuronal functions remains unclear.

Alpha GPC is structurally classified as a phosphatidylcholine, a lecithin phospholipid with a choline attachment. Choline is essential for the brain’s production of acetylcholine, the “learning neurotransmitter” that is crucial to all aspects of cognition, and this function is at the heart of alpha GPC’s nootropic properties.

A water-soluble supplement, alpha GPC is both fast acting and highly bioavailable when taken orally. It crosses the blood-brain barrier soon after ingestion, and most users notice effects within an hour. Each molecule of alpha GPC is made up of about 40% choline, which it delivers directly to the brain.‍

Alpha GPC’s ability to cross the blood-brain border makes it a particularly efficient cholinergic, surpassing other cholinergics and even choline itself at increasing circulating levels of choline in the central nervous system.‍

It has also been shown to increase levels of serotonin‍ and dopamine,‍neurotransmitters that are important in the regulation of mood, energy, and motivation.

Supplementing with alpha GPC may also result in dizziness and low blood pressure in some individuals; if you are prone to hypotension, you should consult a medical professional before taking alpha GPC.

Though no overdoses have been documented, adverse side effects are more commonly reported among users taking high dosages.

Alpha GPC is known to interact with scopolamine, which is used to treat motion sickness, post-operative nausea, and irritable bowel syndrome. Those using scopolamine are advised to consult a physician before taking alpha GPC.

Little research has been done on alpha GPC’s effects on pregnant women, so those who are pregnant or nursing are advised to refrain from use.

Closing Thoughts

Alpha GPC is a safe, well-tolerated, and highly effective nootropic.

It’s been the subject of decades of research and is recognized worldwide as a powerful memory enhancer, prescribed by physicians throughout Europe and Russia for a variety of memory and cognitive disorders.

Studies show that it’s also a neuroprotectant that helps maintain the biochemical balance of the brain. It promotes the production of human growth hormone, which may improve strength, shorten recovery time following exercise, and encourage the building of lean muscle mass.

If you’re interested in a supplement that’s affordable, readily available, and has well-documented benefits for both brain and body, alpha GPC supplementation may be worth a try.

Production

FAQ

A peptide that I purchased recently has less powder in it than others I’ve gotten. Does this mean it doesn’t have the right MG?

Peptides due to their nature come in a variety of sizes and shapes. Normally after the lyophilization process has completed we have a peptide that is in a perfect cake. However there are times when it may break in transit or simply appear differently. This is no way effects the quality or potency of the product. It is simply an aesthetic issue. While we do try to always present a product that looks perfect, on occasion this isn’t possible. Proteins such as LR3 are very large in size and due to the requirement of a buffer will appear larger in size than a mod grf or ghrp. This is also normal.

If A Peptide Is 98% In Purity Then What Is The Remaining 2%?

The purity level indicated on a COA is simply a measurement of aminos that made it into the proper chain to form the peptide. The left over 2% are simply aminos that, for what ever reason, didn’t make it into the proper sequence.

What Are The Purity Levels Of The Peptides You Sell?

AP PEPTIDE will never sell a peptide that is less than 98% in purity from our catalog section. Many of our smaller peptide chains are well into the 99% purity range. We have manufacturing abilities that are quite often beyond the scope of smaller companies and therefore are able to achieve very high purity levels. Proteins such as IGF-1 LR3 are always receptor grade and always above 95% purity.

Two Vials Of The Same Peptide Have Different Amounts Of Powder. Does This Mean They Are Different In Milligrams?

Peptides, due to their nature, come in a variety of sizes and shapes. Normally after the lyophilization process has completed we have a peptide that is in a perfect cake. However there are times when it may break in transit or simply appear differently. This in no way effects the quality or potency of the product. It is simply an aesthetic issue. While we do try to always present a product that looks perfect, on occasion this isn’t possible.

Proteins are very large in size and due to the requirement of a buffer will appear larger in size than a mod grf or ghrp. This is also normal

What Are Your Products Used For?

Peptides and Research serums are manufactured and sold to be used in a laboratory research setting. None of our products are intended for, nor are they manufactured for, diagnostic or therapeutic purposes in humans. Strong Peptide reserves the right to require additional verification of proper intent prior to fulfilling orders. Any orders that we feel aren’t for the specific intended purpose laid out in our Terms and Conditions will be denied. Truthfully, if you are asking this question then you shouldn’t be ordering from AP PEPTIDES.