The association between depression and hypomagnesaemia was marginally insignificant after the sensitivity analysis including only cohort and case–control studies, with a pooled RR of 1.38 ( 95% CI, 0.92–2.07, I2 = 24% ).

In conclusion, the study has demonstrated a potential association between hypomagnesaemia and depression. Further studies assessing the benefits of treatment of hypomagnesaemia in patients with depression are needed. ( Xagena )