Witter later appeared frequently in television series, and rom 1990 to 1994 played Tina Lord on the soap operaOne Life to Live,[7] a role for which she was nominated for the 1991 Soap Opera Digest Award for Outstanding Female Newcomer in Daytime. Witter married TV producer Chuck Lorre in 2001{Karen Witter (2001-2010; divorced) they had two children and are now divorced.