Power lock not working...

Argh. I bought my truck used last summer as the Misses decided we should try RV'ing, so we found a really nice 2500 HD LLY truck. Last night I noticed that the key fob wasn't actuating the door lock on the drivers door, further investigation shows that the door siwtches don't trigger the driver door (but do trigger the passenger door), the key and the inner manual latch work fine (not sticky). All other electronics appear to be functioning fine.

Question: Any one have any experience or heard of this happening? If so what are the potential soutions or other information needed to determine the issue?