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Maggots have a wide variety of uses. Fishermen use them as bait. Live maggots are also used for medical purposes, such as eating dead tissue. Maggots are used in forensic science to calculate an approximate time of death.

Flies reproduce rapidly due to their short life cycle and the large batches of eggs females lay. This can lead to maggot infestation. Maggots can cause myiasis in livestock and humans.