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Betacellulin Proteins (BTC)

On www.antibodies-online.com are 55 Betacellulin (BTC) Proteins from 17 different suppliers available. Additionally we are shipping Betacellulin Antibodies (93) and Betacellulin Kits (63) and many more products for this protein. A total of 223 Betacellulin products are currently listed.

BTC has properties of increasing retinal vascular leakage that could contribute to the development of diabetic retinopathy.

Data suggest a novel receptor-independent role for betacellulin intracellular-domain fragment signaling due to its ability to inhibit cell growth in vitro.

These are the first data that demonstrate an influence of betacellulin upon mesenchymal stem cells and the first to implicate HIF-alpha in betacellulin-mediated proliferation.

The solution structure of the EGF (show EGF Proteins)-like domain of betacellulin has been determined using two-dimensional nuclear magnetic resonance spectroscopy

Betacellulin and heregulin/NDF (show NRG1 Proteins)-alpha are involved in epidermal morphogenesis and/or in maintenance of the differentiated phenotype.

although BTC and EGF share overlapping signaling properties, the ability of BTC to enhance Erk activation occurs independent of Ras.

BTC may play a pivotal role as a local growth factor in promoting the differentiated villous trophoblastic function via ErbB-1 (show EGFR Proteins) in early placentas and in contributing to placental growth through EVT cell function via ErbB-4 (show ERBB4 Proteins) in term placentas.

Betacellulin is expressed in malignant fibrous histiocytoma and is a regulator of tumor growth.

Mouse (Murine) Betacellulin (BTC) interaction partners

BTC induces expansion of neural stem cells and neuroblasts, and promotes neurogenesis in the olfactory bulb and dentate gyrus.

identified hitherto unknown effects of betacellulin (BTC) overabundance in reproduction and suggests BTC as a novel candidate protein for the modulation of fertility.

Betacellulin (BTC) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor.