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The pathway of oxygen through the body consists of the diffusion of oxygen across the alveolar-capillary membrane and then the peripheral tissue membranes, followed by the convective transport of oxygen in the blood. Any transport process will have its choke points and limitations. In the case of oxygen, the constraints can take 1 of 2 forms, perfusion limitation or diffusion limitation.

The pathway of oxygen through the body consists of the diffusion of oxygen across the alveolar-capillary membrane and then the peripheral tissue membranes, followed by the convective transport of oxygen in the blood. Any transport process will have its choke points and limitations. In the case of oxygen, the constraints can take 1 of 2 forms, perfusion limitation or diffusion limitation.