MassIVE is a community resource developed by the NIH-funded
Center for Computational Mass Spectrometry to promote the
global, free exchange of mass spectrometry data.
MassIVE datasets can be assigned ProteomeXchange
accessions to satisfy publication requirements.

Access Public Datasets

Submit Data

Browse publically available datasets
or search by dataset metadata (e.g., species, PI,
etc.). Datasets are available for download as well
as for online browsing of submitted identifications
(for complete datasets). Dataset owners can also
add missing/requested files, update metadata and
add publications to their datasets. Registered
users can comment on datasets so others in the
community can see updates or find pointers to new
analyses of the data.

Search Identifications
(Original and Reanalyses)

Reanalyze Spectra

Search all submitted identifications
in complete datasets and dataset reanalyses. Over
300 million peptide-spectrum matches submitted with
at most 1% false discovery rate are accessible
through this simple interface to search for
peptides, proteins and post-translational
modifications.

Results Comparison

Share Reanalyses

Compare identification results
between datasets or against any reanalyses of
public data. Venn diagrams are used to compare
results at the level of protein, peptide and
spectrum identifications; agreements, disagreements
and unique identifications can be interactively
inspected for assessment of quality of
identifications.

Share your dataset reanalysis
results with the community: reveal new
identifications with novel algorithms / analysis
pipelines or challenge previously submitted
identifications with alternative interpretations
for the same data.

Protein Explorer

MassIVE Knowledge Base

Explore
the translated evidence and sequence coverage of
nearly every human protein, as defined by
systematic reanalysis of 31 terabytes of public
data from >20,000 LC/MS runs and including over
1 million synthetic peptide spectra. Interactive
exploration of protein evidence includes coverage
maps, functional sites, and full provenance and
dataset mapping of every identified peptide.

Browse
the community big data derived MassIVE Knowledge
Base (MassIVE-KB) peptide spectral libraries.
Distilled from 31TB of human proteomics HCD data.
Users can peak at the inside of these libraries,
browse the source data, and track full provenance
of analysis tasks that created these libraries.
Please refer to the
documentation.