It's the year 2124. Energy has become a rare commodity as a consequence of the industrialization of our universe. One of the main energy sources is White Ranium. The large energy companies can hardly find new planets with the raw material, and heavy-duty surface scanners are employed to search for a worthwhile volume of the energy source in the few Ranium mines already known.

Now the Mega Group Troll Factory Unlimited has found some on planet GH-328. Several rival mine crews have been sent to the mine to find the White Ranium and transport it to the space loader — but the material isn't secure until it arrives at the space loader. Until then it can be intercepted by the other mine crews.

In TF22 Mine, each player takes the part of one mine crew, collects White Ranium in the mine, and transports it to the space loader. Each space loader can load up to two units of White Ranium. The mine crew must then return to the base camp in the middle of the mine to recharge their equipment. After that, they can send more units of White Ranium to the space loader. The crew then uses the molecular transporter of the space loader for transport to the base camp.

The player who first transports three units of White Ranium to the space loader wins.