Ear, Eye, Nose, Throat

Gastrointestinal

Genitourinary

Dermatologic

Miscellaneous

Interactions

Drug-Drug interaction

May interact with other highly protein-bound drugs by competing for binding sites.

Route/Dosage

Oral (Adults and children ≥ 12 yr) 500 mg every 12 hr for 3 days.

Oral (Children 4–11 yr) 200 mg (10 mL) every 12 hr for 3 days.

Oral (Children 1–4 yr) 100 mg (5 mL) every 12 hr for 3 days.

Availability

Tablets: 500 mg

Oral suspensionstrawberry: 100 mg/5 mL in 60 mL bottle

Nursing implications

Nursing assessment

Assess frequency and consistency of stools and bowel sounds before and during therapy.

Assess fluid and electrolyte balance and skin turgor for dehydration.

Potential Nursing Diagnoses

Diarrhea (Indications)

Implementation

Oral: Administer with food. Keep container tightly closed and shake well before each administration. Suspension may be stored at room temperature for 7 days; discard unused portion.

Pedi: Tablets contain more than pediatric dose; use solution for patients ≤12 years.

Patient/Family Teaching

Explain to parents administration of medication and monitoring of condition.

Evaluation/Desired Outcomes

Resolution of symptoms: no watery stools, no more than 2 soft stools within the past 24 hr and no unformed stools within the past 48 hr.

nitazoxanide

an antiprotozoal agent used to treat diarrhea caused by Cryptosporidium parvum or Giardia lamblia.

nitazoxanide

A synthetic salicylamide derivative and antiprotozoal that is active against Cryptosporidium parvum or Giardia lamblia infection, and which appears to also have activity against hepatitis B and hepatitis C.

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