We found this problem initially on a clients MS Office installation. Many other applications are affected, its not a MS related problem. We consider this a major issue. Also, here are a couple more related links:

Worked perfectly, we had a Save PDF error on our mac mini and restoring this folder from our time machine backup fixed it no problem! if it happens again, we will seek out the new patch. For now, if you dont want to risk the patch, this works very well. Thanks!