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I'm having the same issue trying to update on Windows 8.1. I'm wondering if this coincided with updating to .NET 4.6.1 from 4.5. I've run the installer as Admin. I've given Everyone full rights to the hive key. It still won't install.

I've now uninstalled, rebooted, and am attempting to install again. This returns a different, but similar, error (attached).

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Works fine for me on Win10 x64. These are two different issues though. 1) is probably restricted access to the registry because of some security application (or rights are set incorrectly in the registry) and 2) is probably CDBurnerXP still running or another application (maybe security) accessing the file.

The installed version of .NET doesn't really matter here because the installer doesn't use .NET.