Clinical representation of neutrophil invasion

Pus

General information about macrophages

Derived from circulating monocytesNot very granularHighly active nucleus for constant transcriptionHave a lot of lysosomes for killing

29

Can macrophages be antigen presenting cells?

Yes.

30

Describe the immune response by macrophages over the course of infection.

They are originally not large in number at the infection site, but those that are present will help with recruitment. Once recruitment takes place, the presence of T cells will help with proliferation of macrophages and their response becomes much greater.

31

Macrophages are strong recruiters of what process?

The inflammatory response

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Primary focus of dendritic cells

Antigen presentation

33

Methods environmental sampling by dendritic cells

Phagocystosis or macropinocytosis

34

Why are dendritic cells so important?

They are the link between innate response and adaptive response; without them, there would be a very weak T cell response to any foreign invader