Calcium Pyrophosphate Dihydrate Deposition Disease

Definition

Calcium pyrophosphate dihydrate deposition disease (CPPD)
is a build up of
calcium crystals
in the joints. These
crystals cause
inflammation
in the joints, which causes arthritis like conditions known as:

Symptoms

In most cases, CPPD does not lead to symptoms. When symptoms occur, they may come and go in acute attacks
called flare-ups.

Pseudoosteoarthritis symptoms are the most common type, especially in the knee. Symptoms may be on both sides of the body, but are generally worse on one side. Pseudoosteoarthritis may cause:

Joint degeneration that worsens over time

Joint misalignment and deformity

Periodic swelling may be seen in chronic cases

Pseudogout symptoms occur more frequently in the knee, but can occur in other joints as well. There may be periods of time when there are no symptoms. Attacks of pseudogout may be spontaneous, or may be brought on by surgery, or illness. Pseudogout may cause:

Sudden, intense pain in one joint

Warmth, redness, and swelling

Fever

Joint damage from the breakdown of cartilage, which can lead to chronic pain

Prevention

Revision Information

This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.