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VI - Neoplasia Flashcards Preview

This term literally means "new growth".

Neoplasia(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

2

An abnormal mass of tissue the growth of which exceeds and is uncoordinated with that of the normal tissues and persists in the same excessive manner after the cessation of stimuli which evoked the change.

Neoplasm(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

3

Study of tumors.

Oncology(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

4

Benign or malignant?Localized

Benign(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

5

Benign or malignant?Amenable to surgical removal

Benign(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

6

Benign or malignant?Invades and destroys adjacent tissues.

Malignant(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

7

What are the two basic components of tumors?

Parenchyma and Stroma(TOPNOTCH)

8

Benign or malignant?Metastasis

Malignant(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

9

This component of tumors largely determines its biologic behavior.

Parenchyma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

10

This component of tumors determines the name of the growth.

Parenchyma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

11

This component of tumors is crucial to the growth of neoplasms since it carries the blood supply and provides support to the growth of cells.

Stroma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

12

Benign or malignant?Fibroma

Benign(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.176

13

Benign or malignant?Chondroma

Benign(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.176

14

Benign or malignant?Adenoma

Benign(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.176

15

Benign or malignant?Hepatoma

Malignant(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.176

16

Benign or malignant?Papilloma

Benign(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.176

17

Malignant neoplasms arising in mesenchymal tissue or its derivatives.

Sarcomas(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.175

18

Benign tumor arising in fibrous tissue is called?

Fibroma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.175

19

A benign cartilagenous tumor is called?

Chondroma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.175

20

This is a benign epithelial neoplasm which produces glandular patterns or neoplasms derived from glands but not necessarily exhibit glandular patterns

Adenoma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.175

21

These are benign epithelial neoplasms, growing on any surface that produce microscopic or macroscopic finger-like fronds.

Papillomas(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

22

A mass that projects above a mucosal surface to form a macroscopically visible structure.

Dysplasia (TOPNOTCH)

RAS oncogene qualitatively changes function of proto-oncogene through which form of mutation?

Point mutations (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 286

104

Chemical carcinogen implicated in the causation of mesothelioma

Asbestos(TOPNOTCH)

105

A 56 year old woman with a breast mass has a preoperative diagnosis of invasive ductal carcinoma by core needle biopsy, with no palpable axillary lymph nodes. She undergoes surgery where her breast mass is injected with a blue dye, and the first axillary node that takes up the dye is submitted to pathology. Which method is next done on the node if the surgeon wants to know within minutes if there is metastasis? (A) fine needle aspiration (B) frozen section (C) immunohistochemistry (D) flow cytometry

frozen section (TOPNOTCH)Robbins Basic Pathology, 8th Ed, p 220

106

A 25 year old male with an intranasal mass undergoes a tissue biopsy that shows malignant round cells. The pathologist needs to know if it is an undifferentiated carcinoma or a lymphoma. What can be done to differentiate? (A) Frozen section (B) Immunohistochemistry (C) Flow cytometry (D) serologic tumor markers

A 12 year old female presents with pallor and gum bleeding. A complete blood count with peripheral smear shows numerous blasts. What is needed to be done on her bone marrow for a more precise diagnosis? (A) frozen section (B) papanicolau smear (C) aspiration and flow cytometry (D) serologic tumor markers