The practice of bark distillation, which produces an oil that smells strongly of aniseed and contains 80-97% methyl chavicol as well as limonene, anethole, and linalol, is threatening the survival of Ravensara anisata, the Madagascan tree from which the oil is extracted.

For instance, it was demonstrated that Ocimum sanctum essential oil and two of its main components, methyl chavicol and linalool, target the structural and functional integrity of the cytoplasmic membrane in Candida (Khan et al.

The high economic value of this plant is due to the presence of phenyl propanoids, like eugenol, chavicol and their derivatives, or terpenoids, like the monoterpene alcohol linalool, methyl cinnamate and limonene [27].

Methyl chavicol from Aldrich (USA), linalool from Aldrich (Germany), carvone from SAFC (USA), and limonene from Himedia (India) were purchased, whereas all inorganic chemicals were of analytical grade and were procured from E.

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