2nd International Conference and Exhibition on Materials Science and Chemistry

Hydroxyapatite via the formula Ca10(PO4)6OH2 (HAP), which is an important member of calcium phosphate family, has been
useful applications in biomedical, that is due to non-toxicity, biocompatibility and high osteoconductivity. There are many
studies for improve HAP properties, one of them to make it more useful is doped HAP with different metal ions such as Ba2+, Co2+,
Sr2+, Zn2+, etc. On the other hands incorporation of HAP with organic polymers such as chitosan (CS), gelatin, collagen, etc., that
made it operational, would be used in biomaterial engineering. In this work, Mg2+ doped nano-hydroxyapatite/chitosan (Mg-nHAP/
CS) fabricated by a sol-gel method. Product was characterized by powder X-ray spectroscopy (XRD), Fourier transform infrared
spectroscopy (FTIR), scanning electron microscopy (SEM) and energy dispersive X-ray (EDX) spectroscopy. XRD results shown
that dopants slightly effect on lattice parameters and crystallinity. On the other hand compared to the diffraction peaks of highly
crystalline HAP, the broadening of the diffraction patterns shows low crystallinity of synthesized samples. According to the FTIR
results it is shown that the typical peaks of (OH-) and (PO4
3-) groups vibrations at 3616 and 1081 cm-1. Based on the SEM images, it is
observed that unique particle morphology with different shapes. The EDX spectra showed the elemental composition and all samples
were pure. The synthesis samples were also found to be nontoxic based on the MTT assay. Bioactivity of a nHAp predicted from
the apatite formation on its surface in SBF. Results suggested that crystallinity of nHAP decreases with doped by Mg2+ and natural
polymer CS. The prepared product also showed improvement in nHAP biological properties.

Biography

Mina Samadipour has done her BSc in Applied Chemistry and MSc in Inorganic Chemistry. She has expertise in R&D of synthesis and characterization of bioproperties of inorganic chemical materials as nano-hydroxyapatite. She is currently working on the biomedical properties of calcium phosphate family to create new pathways for improving healthcare.