You could be having disk IO latency. Run a perfmon, and capture the following counters:

PhysicalDisk\Avg. Disk/Sec Read
PhysicalDisk\Avg. Disk/Sec Write

If either of these are exceeding .020, you have a disk bottleneck. If thats the case you may need to revisit
the way you have your storage set up, or consider putting the file server and GC roles on different machines.

So how IS your dns setup? Any event log errors on servers or workstations. Do you have any ISP's DNS servers listed anywhere in TCP/IP ? Otherwise how are your server and clients setup to resolve dns queries etc?

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