"Getting older," the actress tells Health magazine for its July/August cover story, now on newsstands. "It's like, 'Yeah, this is who I am, f––– off.' As opposed to, 'This is who I am, I'm sorry.' You know, there's something about getting older and owning who you are that is a good thing."

Louis-Dreyfus's confident, easy-going attitude extends elsewhere in her life, including balancing work and her family (she and Brad Hall have been married for 26 years and have two sons together).

"Of course you can't have it all," says Louis-Dreyfus. "That's absurd! It doesn't mean you shouldn't pursue what you desire. It's not possible to do and have everything all the time. So you have to make choices … if you realize that, then I think you can free yourself up to prioritize."