G6PD Deficiency

A 25-year-old man with Mediterranean ancestry presents with jaundice. He also reports being unusually tired and believes this may be due to his recent recovery from mononucleosis. He was found to be anemic with a hemoglobin of 9 g/dL. His peripheral blood smear revealed bite cells and Heinz bodies.

(M1.HE.72)
A 21-year-old African American male with a history of HIV presents to the clinic with a complaint of cough, shortness of breath, and fever that has seemed to slowly progress over the past week. Upon questioning, he admits to not being able to take his HAART regimen due to recently losing his health insurance. Concerned, the physician pursues a full workup. The patient is found to have a pneumonia caused by a gram-positive, acid fast aerobe, and the physician prescribes the appropriate medication. After 1 day of taking the medication, the patient returns to the physician with complaints of severe weakness and dark colored urine. On exam, the physician notes that the patient is jaundiced and has splenomegaly. Which figure demonstrates the mode of inheritance of this patient's genetic condition?
Review Topic

(M1.HE.27)
A 3-month-old African American infant presents to the hospital with 2 days of fever, "coke"-colored urine, and jaundice. The pregnancy was uneventful except the infant was found to have hyperbilirubinemia that was treated with phototherapy. The mother explains that she breastfeeds her child and recently was treated herself for a UTI with trimethoprim-sulfamethoxazole (TMP-SMX). Which of the following diseases is similarly inherited as the disease experienced by the child?
Review Topic

(M1.HE.86)
A 32-year-old Greek male presents with a rash consistent with dermatitis herpetiformis and is treated with a course of oral dapsone. Over the following several days he becomes increasingly fatigued and experiences persistent back pain. Complete blood count reveals a normocytic anemia and urinalysis shows hemoglobinuria. Results from a peripheral blood smear are shown in Figure A. Which of the following is most likely responsible for this patient’s symptoms?
Review Topic