The 1H18 performance of companies that make up ~80% of the joint reconstruction market achieved 4.1% growth vs. 1H17. These companies posted 2.4% growth in 1H17 vs. 1H16. Here is a look at past activity and future predictions for hip, knee and extremities.

We've tracked 31 mergers and acquisitions in the spine space from 2017 through mid-September 2018...with eight of them in just the last four weeks. The segment includes nearly 300 companies, globally; players need broad portfolios or novel technologies to vie for market share today.

"There remains a shortage of venture capital focused on the musculoskeletal space. This creates opportunity for investors who are funding startups and challenges for entrepreneurs who are raising capital. At MNVC, we will hear from financial and strategic investors that are funding startups to get their sense of the current state of investing."--Gary Stevenson, co-host of MNVC.

SI-BONE publicly filed a registration statement for a proposed US $97.7MM IPO, and applied to list on NASDAQ as SIBN. Proceeds will primarily support commercialization of the iFuse Implant System to treat sacroiliac joint dysfunction.