Being wise is good for your health — review looks at emerging science of wisdom

May 14, 2019 – Can science measure what it means to be wise? A growing body of evidence suggests that wisdom is a complex concept that contributes to mental health and happiness, according to a review in the May/June issue of Harvard Review of Psychiatry. The journal is published in the Lippincott portfolio by Wolters Kluwer.

Different aspects of wisdom may be traced to specific areas of the brain, and might possibly be enhanced by behavioral interventions, suggests the article by Dilip V. Jeste, MD, and Ellen E. Lee, MD, of the Sam and Rose Stein Institute for Research on Aging, University of California San Diego. They write, “Wisdom has important implications at both individual and societal levels, and warrants further research as a major contributor to human thriving.”

Research Helps Define Wisdom and Its Impact on Our Lives

What is wisdom? While it has been discussed in religion and philosophy for centuries, scientific research on wisdom has accelerated in the past few decades. While it may seem impossible to define and measure wisdom, Drs. Jeste and Lee note that research has demonstrated the validity of other psychological constructs such as consciousness, stress, and resilience.

Based on an in-depth review from ancient writings to modern times, Drs. Jeste and Lee propose that wisdom can be defined as “a complex human trait with several specific components: social decision making, emotion regulation, prosocial behaviors, self-reflection, acceptance of uncertainty, decisiveness, and spirituality.” Over the years, several approaches to measuring wisdom have been proposed, although each has its limitations.

The basic concept of wisdom has always been the same, suggesting that it “probably has an underlying neurobiological basis.” Drs. Jeste and Lee propose a model of the neurobiology of wisdom, localized mainly to two areas of the brain: the prefrontal cortex and limbic striatum. “Emerging research suggests that wisdom is linked to better overall health, well-being, happiness, life satisfaction, and resilience,” the researchers add.

Wisdom seems to increase with age despite decreased physical health, and has been linked to better quality of life. Enhancing wisdom in older age may even confer an evolutionary advantage: “Despite the loss of their own fertility and physical health, older adults help increase their children’s well-being, health, longevity, and fertility – the ‘Grandma Hypothesis’ of wisdom.” The authors propose a model of the development of wisdom, involving genetics, environment, and epigenetics.

Wisdom’s positive effects on health and well-being raise an intriguing question: Can wisdom be increased? While research is limited so far, psychosocial and possibly biological interventions to enhance the function of brain areas involved might lead to enhanced wisdom. The researchers call for “a greater emphasis on promoting wisdom through our educational systems from elementary to professional schools.”

Such efforts might have important benefits, with increases in wisdom leading to improved health and well-being on the societal as well as individual level. Drs. Jeste and Lee conclude, “There is a need to expand empirical research on wisdom, given its immense but largely untapped potential for enhancing mental health of individuals and promoting well-being of the society at large.”

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Click here to read “The Emerging Empirical Science of Wisdom”

DOI: 10.1097/HRP.0000000000000205

About the Harvard Review of Psychiatry

The Harvard Review of Psychiatry is the authoritative source for scholarly reviews and perspectives on a diverse range of important topics in psychiatry. Founded by the Harvard Medical School Department of Psychiatry, the journal is peer reviewed and not industry sponsored. It is the property of Harvard University and is affiliated with all of the Departments of Psychiatry at the Harvard teaching hospitals. Articles encompass major issues in contemporary psychiatry, including neuroscience, epidemiology, psychopharmacology, psychotherapy, history of psychiatry, and ethics.

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