Average Follow-up Time Detail"Subjects have been followed up since 1993/94 for an average time of 12 years within three examination waves (t1: 1993/94; t2: 1997/98; t3: 2005/07)."

Exposure Detail"Physical activity was assessed with a questionnaire at baseline. Participants were asked about their current and past sport activities using open-ended questions. Additionally, they were asked if they performed the respective activities on a regular basis and how many hours they spent on them per week. According to current WHO recommendations [31] subjects were classified as physically active if they reported at least one sportactivity, for at least once a week for two hours over any year-long interval. Subjects were classified as physically active throughout their whole lifetime if they fulfilled the above criteria during childhood (6–14 years), youth (14–20 years), young adulthood (20–40 years), mid-adulthood (40–60 years), and at t1. The remaining subjects were classified as 'never' or 'not continually physically active' according to their statements."

Ethnicity DetailNo data on ethnicity was reported, however all participants reside in Germany.

Age DetailThe 381 initially healthy participants from the 1930–32 birth cohort who completed the 3rd examination wave had an average age of 74 years.