'Love and Other Drugs' Trailer: Rx for Jake Gyllenhaal and Anne Hathaway

Director Edward Zwick, who generally dabbles in heavy dramas and actioners ('Glory,' 'Legends of the Fall,' 'The Siege,' 'Blood Diamond') hasn't done a romantic-comedy since 1986, when he teamed Demi Moore and Rob Lowe as lovers whose one-night stand turns into a budding relationship; the film followed their struggles with the ups and downs of romance and love.