The intracellular IL10 expression within the M2 population following exposure to (A) recombinant IL6 (400 pg/mL) and (B) ADSC-CM compared to treatment with unconditioned control media. (C and D) Intracellular M2 IL10 expression following ADSC-CM treatment with either anti-IL6 blocking antibody (C) or anti-PTX3 blocking antibody (D) compared to ADSC-CM treatment. Representative flow cytometry histograms are from a randomly selected healthy lean participant. A full colour version of this figure is available at https://doi.org/10.1530/JME-18-0078.

The intracellular IL10 expression within the M2 population following exposure to (A) recombinant IL6 (400 pg/mL) and (B) ADSC-CM compared to treatment with unconditioned control media. (C and D) Intracellular M2 IL10 expression following ADSC-CM treatment with either anti-IL6 blocking antibody (C) or anti-PTX3 blocking antibody (D) compared to ADSC-CM treatment. Representative flow cytometry histograms are from a randomly selected healthy lean participant. A full colour version of this figure is available at https://doi.org/10.1530/JME-18-0078.