tag:blogger.com,1999:blog-220939332007-05-31T15:49:52.112-05:00MindBlogDeric BowndsBlogger480125tag:blogger.com,1999:blog-22093933.post-18721754041833677062007-05-31T15:38:00.000-05:002007-05-31T15:49:52.137-05:00PLEASE NOTE! MindBlog/RSS web URL changeBecause I am upgrading my blogger setup to use labels (keywords) I'm having to assign a new URL to MindBlog. <br /><br />The new URL is http://mindblog.dericbownds.net<br /><br />Please point your RSS feeds to this new url, and change your bookmarks for the blog. <br /><br />If you click the Feedburner icon, it will resubscribe you. <br /><br />Please allow several days for these changes to take full effect. (i.e. the resubscription working).Deric Bowndstag:blogger.com,1999:blog-22093933.post-2263195390172033852007-05-31T06:24:00.000-05:002007-05-31T06:25:20.074-05:00Anheuser-Busch would never do this..comments the friend who emailed me this video of a Guiness commercial: Married to a Man<br /><object height="350" width="425"><param name="movie" value="http://www.youtube.com/v/zSZYHl0EfQc"><param name="wmode" value="transparent"><embed src="http://www.youtube.com/v/zSZYHl0EfQc" type="application/x-shockwave-flash" wmode="transparent" height="350" width="425"></embed></object>Deric Bowndstag:blogger.com,1999:blog-22093933.post-84557514618553882172007-05-31T06:16:00.000-05:002007-05-31T06:15:07.937-05:00Why don’t we do what we know works better?I mull frequently about an issue that I’m sure readers of this blog are familiar with. Having assembled a fairly extensive toolkit of techniques to maintain personal poise, sanity, vitality, etc. (tools of the sort mentioned in the essay on my website titled “Mindstuff: a guide for the curious user.”), how is it that I don’t use them more religiously to maintain those desired qualities? Well…. there are some limits intrinsic to the fact that they are constructions of my adult mind, mainly over the past 15—20 years. They require attention and energy for their maintenance, unlike the pandora’s box of less useful older habits and ways-to-be-in-the-world that formed in my youth, and are more hard wired into place. During periods of inattention or low energy, I don’t notice the these older autopilots and temperaments slipping back into place to resume their residency. This, I suppose, is why practitioners of various healthy mind regimes (schools of meditation, cognitive therapies, or whatever) keep saying: “How do you get to Carneige Hall? Practice, practice, practice!”<br /><br />Joseph LeDoux perhaps puts it better in <a href="http://www.slate.com/id/2165043/pagenum/all/#page_start">some recent comments</a>:<br /><blockquote>One of the things I've learned about the brain is that anxiety and stress breed anxiety and stress. So, it makes sense that we should do things to reduce anxiety and stress in our daily lives, like the sorts of breathing exercises that are used in meditation. These are effective in part because they push the autonomic nervous system toward its parasympathetic side, slowing the driving force of the sympathetic system and reducing the arousal level of the body and the brain. Do I do these exercises? Not as often or as effectively as I probably should. But cardiologists probably don't always eat the right things or exercise as much as they should, either. It's one thing to know what to do, and another to do it. (If we could figure out that discordance, we'd really know something.)</blockquote>Deric Bowndstag:blogger.com,1999:blog-22093933.post-60213050116622900212007-05-31T06:10:00.000-05:002007-05-31T06:11:26.236-05:00Guide to psychology blogs...PsyBlog publishes the <a href="http://www.spring.org.uk/2007/05/guide-to-psychology-blog-o-sphere-part.php">first part of a two part guide</a> to other psychology blog.Deric Bowndstag:blogger.com,1999:blog-22093933.post-7025926345606024382007-05-30T06:40:00.000-05:002007-05-30T06:38:27.174-05:003rd and 1st person narrative in personality change<a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://dericbownds.net/uploaded_images/Stories.png"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 320px;" src="http://dericbownds.net/uploaded_images/Stories.png" alt="" border="0"></a>Benedict Carey writes a piece in the Tuesday NY Times science section (<a href="http://dericbownds.net/uploaded_images/Carey_NYT.pdf">PDF here</a>) reviewing work done by a number of researchers on on how the stories people tell themselves (and others) about themselves do or don't help with making adaptive behavior changes. Third person narratives, in which subjects view themselves from a distance - as actors in their own narrative play - correlate with a higher sense of personal power and ability to make personality changes. First person narratives - in which the subject describes the experience of being immersed in their personal plays - are more likely than third person narratives to correlate with passivity and feeling powerless to effect change. This reminds me of Marc Hauser's distinction of being a moral agent or a moral patient. The third person can be a more metacognitive stance, thinking about oneself in a narrative script while the first person can be a less reflective acting out of the script.Deric Bowndstag:blogger.com,1999:blog-22093933.post-79332646538392700032007-05-30T06:35:00.000-05:002007-05-30T06:36:57.828-05:00"The Secret" scam....More of Michael Schermer's <a href="http://www.sciam.com/article.cfm?chanID=sa006&colID=13&amp;articleID=72C0E84D-E7F2-99DF-3D281803B61E675C">terrific debunking</a> of popular myth in the June Scientific American... Some clips:<br /><blockquote>An old yarn about a classic marketing con game on the secret of wealth instructs you to write a book about how to make a lot of money and sell it through the mail. When your marks receive the book, they discover the secret--write a book about how to make a lot of money and sell it through the mail.<br /><br />A confidence scheme similar to this can be found in The Secret (Simon &amp; Schuster, 2006), a book and DVD by Rhonda Byrne and a cadre of self-help gurus that, thanks to Oprah Winfrey's endorsement, have now sold more than three million copies combined. The secret is the so-called law of attraction. Like attracts like. Positive thoughts sally forth from your body as magnetic energy, then return in the form of whatever it was you were thinking about. Such as money.<br /><br />A pantheon of shiny, happy people assures viewers that The Secret is grounded in science: "It has been proven scientifically that a positive thought is hundreds of times more powerful than a negative thought." No, it hasn't. "Our physiology creates disease to give us feedback, to let us know we have an imbalanced perspective, and we're not loving and we're not grateful." Those ungrateful cancer patients. "You've got enough power in your body to illuminate a whole city for nearly a week." Sure, if you convert your body's hydrogen into energy through nuclear fission. "Thoughts are sending out that magnetic signal that is drawing the parallel back to you." But in magnets, opposites attract--positive is attracted to negative. "Every thought has a frequency.... If you are thinking that thought over and over again you are emitting that frequency."<br /><br />The brain does produce electrical activity from the ion currents flowing among neurons during synaptic transmission, and in accordance with Maxwell's equations any electric current produces a magnetic field...The brain's magnetic field... quickly dissipates from the skull and is promptly swamped by other magnetic sources, not to mention the earth's magnetic field ... which overpowers it by 10 orders of magnitude!<br /><br />Ceteris paribus, it is undoubtedly better to think positive thoughts than negative ones. But in the real world, all other things are never equal, no matter how sanguine your outlook. Just ask the survivors of Auschwitz. If the law of attraction is true, then the Jews--along with the butchered Turkish-Armenians, the raped Nanking Chinese, the massacred Native Americans and the enslaved African-Americans--had it coming.<br /><br />Oprah, please, withdraw your support of this risible twaddle--as you did when you discovered that James Frey's memoir was a million little lies--and tell your vast following that prosperity comes from a good dollop of hard work and creative thinking, the way you did it.</blockquote>Deric Bowndstag:blogger.com,1999:blog-22093933.post-62551950978477385072007-05-29T07:28:00.000-05:002007-05-29T07:26:22.297-05:00Neural correlates of social cognitionVittorio Gallese writes an interesting summary in Proc. Roy. Soc. B titled "Before and below ‘theory of mind’: embodied simulation and the neural correlates of social cognition." (PDF <a href="http://dericbownds.net/uploaded_images/Gallese_PhilTransRSocB_2007.pdf">here</a>). His abstract:<br /><blockquote>The automatic translation of folk psychology into newly formed brain modules specifically dedicated to mind-reading and other social cognitive abilities should be carefully scrutinized. Searching for the brain location of intentions, beliefs and desires—as such—might not be the best epistemic strategy to disclose what social cognition really is. The results of neurocognitive research suggest that in the brain of primates, mirror neurons, and more generally the premotor system, play a major role in several aspects of social cognition, from action and intention understanding to language processing. This evidence is presented and discussed within the theoretical frame of an embodied simulation account of social cognition. Embodied simulation and the mirror neuron system underpinning it provide the means to share communicative intentions, meaning and reference, thus granting the parity requirements of social communication.<br /></blockquote>Deric Bowndstag:blogger.com,1999:blog-22093933.post-18637088777465469172007-05-29T07:22:00.000-05:002007-05-29T07:22:35.711-05:00Why Americans resist scientific ideas.Paul Bloom and Deena Skolnick Weisberg offer a <a href="http://www.sciencemag.org/cgi/content/abstract/316/5827/996">fascinating review</a> of the childhood origins of adult resistance to science (PDF <a href="http://dericbownds.net/uploaded_images/Bloom_Weisberg.pdf">here</a>), pointing out that it derives from clinging to incorrect intuitive physics and psychology assumptions that are a normal part of child develpment. They review developmental data that suggests:<br /><blockquote>...that resistance to science will arise in children when scientific claims clash with early emerging, intuitive expectations. This resistance will persist through adulthood if the scientific claims are contested within a society, and it will be especially strong if there is a nonscientific alternative that is rooted in common sense and championed by people who are thought of as reliable and trustworthy. This is the current situation in the United States, with regard to the central tenets of neuroscience and evolutionary biology. These concepts clash with intuitive beliefs about the immaterial nature of the soul and the purposeful design of humans and other animals, and (in the United States) these beliefs are particularly likely to be endorsed and transmitted by trusted religious and political authorities. Hence, these fields are among the domains where Americans' resistance to science is the strongest.<br /><br /><br /></blockquote>Deric Bowndstag:blogger.com,1999:blog-22093933.post-165302446586095422007-05-28T09:49:00.000-05:002007-05-28T09:54:06.017-05:00Adding labels or keywords to MindBlog for indexing... some glitchesI'm going to be adding labels (keywords) to new and older blog posting over the next period of time, and it appears that any change in an old posting makes it appear to some RSS readers as a new posting. Sorry about that.<br /><br />I hope then to figure out how to install one of the widgets that lets you click on a keyword in the list of keywords or labels and see a list of all the relevant blog postings. If any of you are expert at this and could point me in the right direction I would be grateful.Deric Bowndstag:blogger.com,1999:blog-22093933.post-83010626136507501012007-05-28T09:34:00.000-05:002007-05-28T09:41:04.726-05:00Embodying emotionThis is the title of an <a href="http://www.sciencemag.org/cgi/content/abstract/316/5827/1002">interesting review</a> by Niedenthal (<a href="http://dericbownds.net/uploaded_images/Niedenthal.pdf">PDF here</a>) on how manipulations of facial expression and posture in the laboratory can influence how emotions are processed. Whether we are similing or frowning, or hunched over or upright, can profoundly influence our emotional reactions to positive or negative input. Here is the abstract:<br /><blockquote>Recent theories of embodied cognition suggest new ways to look at how we process emotional information. The theories suggest that perceiving and thinking about emotion involve perceptual, somatovisceral, and motoric reexperiencing (collectively referred to as "embodiment") of the relevant emotion in one's self. The embodiment of emotion, when induced in human participants by manipulations of facial expression and posture in the laboratory, causally affects how emotional information is processed. Congruence between the recipient's bodily expression of emotion and the sender's emotional tone of language, for instance, facilitates comprehension of the communication, whereas incongruence can impair comprehension. Taken all together, recent findings provide a scientific account of the familiar contention that "when you're smiling, the whole world smiles with you."<br /><br /></blockquote><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://dericbownds.net/uploaded_images/Simle_frown.gif"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 320px;" src="http://dericbownds.net/uploaded_images/Simle_frown.gif" alt="" border="0"></a><br />Two ways in which facial expression has been manipulated in behavioral experiments. (Top) In order to manipulate contraction of the brow muscle in a simulation of negative affect, researchers have affixed golf tees to the inside of participants' eyebrows. Participants in whom negative emotion was induced were instructed to bring the ends of the golf tees together, as in the right panel. [Photo credit: Psychology Press]. (Bottom) In other research, participants either held a pen between the lips to inhibit smiling, as in the left panel, or else held the pen between the teeth to facilitate smiling.Deric Bowndstag:blogger.com,1999:blog-22093933.post-59319343105663697362007-05-28T09:37:00.000-05:002007-05-28T09:37:18.896-05:00The New Synthesis in Moral PsychologyThe <a href="http://www.sciencemag.org/cgi/content/abstract/316/5827/998">article</a> of this title by Haidt is worth passing on to those of you who are interested in this area (PDF <a href="http://dericbownds.net/uploaded_images/haidt.pdf">here</a>). Here is the abstract:<br /><blockquote>People are selfish, yet morally motivated. Morality is universal, yet culturally variable. Such apparent contradictions are dissolving as research from many disciplines converges on a few shared principles, including the importance of moral intuitions, the socially functional (rather than truth-seeking) nature of moral thinking, and the coevolution of moral minds with cultural practices and institutions that create diverse moral communities. I propose a fourth principle to guide future research: Morality is about more than harm and fairness. More research is needed on the collective and religious parts of the moral domain, such as loyalty, authority, and spiritual purity.</blockquote>Deric Bowndstag:blogger.com,1999:blog-22093933.post-33888559966304039802007-05-27T10:04:00.000-05:002007-05-27T16:34:54.511-05:00A Wedding in MexicoPictures: Deric and his son Jonathan in exile while the women are getting ready; the ceremony; Jonathan and Shana in the sunset.<br /><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://dericbownds.net/uploaded_images/Wedding1.png"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 320px;" src="http://dericbownds.net/uploaded_images/Wedding1.png" alt="" border="0" /></a><br /><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://dericbownds.net/uploaded_images/Wedding2.png"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 320px;" src="http://dericbownds.net/uploaded_images/Wedding2.png" alt="" border="0" /></a><br /><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://dericbownds.net/uploaded_images/Wedding3.png"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 320px;" src="http://dericbownds.net/uploaded_images/Wedding3.png" alt="" border="0" /></a>Deric Bowndstag:blogger.com,1999:blog-22093933.post-1139519323940549852006-02-09T15:04:00.000-06:002007-05-26T10:52:30.444-05:00Mirror or Empathy Neurons, the DNA of psychology?Our brains have multiple mirror neuron systems that are active not only during our own actions and emotions, but also when we are observing similar actions, emotions, or intentions in others.<br /><br />Quoting <a href="http://http://www.edge.org/3rd_culture/ramachandran06/ramachandran06_index.html">V.S. Ramachandran</a> : "Researchers at UCLA found that cells in the human anterior cingulate, which normally fire when you poke the patient with a needle ("pain neurons"), will also fire when the patient watches another patient being poked. The mirror neurons, it would seem, dissolve the barrier between self and others. <a href="http://biology.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pbio.0030079">[1]</a> I call them "empathy neurons" or "Dalai Llama neurons". (I wonder how the mirror neurons of a masochist or sadist would respond to another person being poked.) Dissolving the "self vs. other" barrier is the basis of many ethical systems, especially eastern philosophical and mystical traditions. This research implies that mirror neurons can be used to provide rational rather than religious grounds for ethics (although we must be careful not to commit the is/ought fallacy)."<br />See: Grasping the Intentions of Others with One's Own Mirror Neuron System<br /><a href="http://biology.plosjournals.org/perlserv/?request=get-document&amp;doi=10.1371/journal.pbio.0030079">Marco Iacoboni et al. 2005.<br /></a><br />Quoting from the Jan 10, 2006 NYTimes article "Cells that Read Minds" by Sandra Blakeslee , an interview with the discoverer of mirror cells:<br /><br />"We are exquisitely social creatures," Dr. Rizzolatti said. "Our survival depends on understanding the actions, intentions and emotions of others."<br /><br />He continued, "Mirror neurons allow us to grasp the minds of others not through conceptual reasoning but through direct simulation. By feeling, not by thinking."<br /><br />The discovery is shaking up numerous scientific disciplines, shifting the understanding of culture, empathy, philosophy, language, imitation, autism and psychotherapy.<br /><br />Everyday experiences are also being viewed in a new light. Mirror neurons reveal how children learn, why people respond to certain types of sports, dance, music and art, why watching media violence may be harmful and why many men like pornography.Deric Bowndstag:blogger.com,1999:blog-22093933.post-73535243723173828652007-05-25T09:10:00.000-05:002007-05-25T09:09:08.333-05:00A neural link between hand muscle excitability and numerical counting<a href="http://jocn.mitpress.org/cgi/content/abstract/19/4/684">Sato et al.</a> do an interesting experiment showing that excitability of our hand muscles changes when we perform a visual (non-numerical) counting task, reinforcing the idea that finger counting represents an basic embodied strategy for number learning. (PDF <a href="http://dericbownds.net/uploaded_images/sato.pdf">here</a>.) Their abstract:<br /><blockquote>Developmental and cross-cultural studies show that finger counting represents one of the basic number learning strategies. However, despite the ubiquity of such an embodied strategy, the issue of whether there is a neural link between numbers and fingers in adult, literate individuals remains debated. Here, we used transcranial magnetic stimulation to study changes of excitability of hand muscles of individuals performing a visual parity judgment task, a task not requiring counting, on Arabic numerals from 1 to 9. Although no modulation was observed for the left hand muscles, an increase in amplitude of motor-evoked potentials was found for the right hand muscles. This increase was specific for smaller numbers (1 to 4) as compared to larger numbers (6 to 9). These findings indicate a close relationship between hand/finger and numerical representations.<br /></blockquote>Deric Bowndstag:blogger.com,1999:blog-22093933.post-34213122554196071382007-05-25T09:00:00.000-05:002007-05-25T09:06:51.029-05:00Gene crucial to learning and memory unique in humansZu et al <a href="http://www3.interscience.wiley.com/cgi-bin/abstract/114250882/ABSTRACT">report</a> that a human-specific gene mutation (not seen in other primates) leads to the origin of a novel splice form of neuropsin (KLK8), a protein involved in learning and memory. This may be one of the genes that have been positively selected during human evolution Their abstract:<br /><blockquote>Neuropsin (kallikrein 8, KLK8) is a secreted-type serine protease preferentially expressed in the central nervous system and involved in learning and memory. Its splicing pattern is different in human and mouse, with the longer form (type II) only expressed in human. Sequence analysis suggested a recent origin of type II during primate evolution. Here we demonstrate that the type II form is absent in nonhuman primates, and is thus a human-specific splice form. With the use of an in vitro splicing assay, we show that a human-specific T to A mutation (c.71-127T>A) triggers the change of splicing pattern, leading to the origin of a novel splice form in the human brain. Using mutation assay, we prove that this mutation is not only necessary but also sufficient for type II expression. Our results demonstrate a molecular mechanism for the creation of novel proteins through alternative splicing in the central nervous system during human evolution. </blockquote>Deric Bowndstag:blogger.com,1999:blog-22093933.post-91831048862121168752007-05-24T07:53:00.000-05:002007-05-24T07:53:24.911-05:00Boundaries of Experience and SelfI've been slogging through journals that accumulated during my snow-bird phase last winter, and am going through a pile of back issues of the Journal of Consciousness Studies. I came across a review by Chris Nunn of a conference held by the consciousness and experiential psychology section of the British Psychological Association, St. Anne's College at Oxford in Sept. of 2006. on "Exploring the Boundaries of Experience and Self." Nunn notes that a more appropriate title for the conference might have been "Demonstrating Ambiguities of Language and Meaning Used in Relation to Experience and Self." I think his brief review (<a href="http://dericbownds.net/uploaded_images/NunnBPS.pdf">PDF here</a>) is worth reading.Deric Bowndstag:blogger.com,1999:blog-22093933.post-20804330605889579042007-05-24T07:31:00.000-05:002007-05-24T07:50:20.165-05:00View from my window - Isla Mujeres<a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://dericbownds.net/uploaded_images/Isla2.png"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 200px;" src="http://dericbownds.net/uploaded_images/Isla2.png" alt="" border="0"></a><br /><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://dericbownds.net/uploaded_images/Isla1.png"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 200px;" src="http://dericbownds.net/uploaded_images/Isla1.png" alt="" border="0"></a>Turns out I can get wireless in the hotel lobby. I'm at the Playa Media Luna on Isla Mujeres, off of Cancun, the occasion being my 33 year old son's destination wedding (costs a lot less than the U.S.). I want to thank readers who sent annonymous or personal comments on this blog. If I needed any reinforcement to continue the effort, it certainly was there! Also, a number of people indicated they liked the personal material I put in the blog (music, personal attitudes and experience). This is why I'm inflicting the pictures in today's posts on you.Deric Bowndstag:blogger.com,1999:blog-22093933.post-47393130544500745252007-05-24T07:42:00.000-05:002007-05-24T07:43:58.343-05:00Spring at Twin ValleyThis is a blog draft I saved to post while I'm away...these pictures around my Twin Valley Road home in Middleton, Wisconsin just before leaving for Mexico. <br />They show why I like to be in Wisconsin in the spring.<br /><br /><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://dericbownds.net/uploaded_images/spring1.png"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 200px;" src="http://dericbownds.net/uploaded_images/spring1.png" alt="" border="0"></a><br /><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://dericbownds.net/uploaded_images/Spring2.png"><br /></a><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://dericbownds.net/uploaded_images/Spring2.png"><img style="margin: 0px auto 10px; display: block; text-align: center; cursor: pointer; width: 200px;" src="http://dericbownds.net/uploaded_images/Spring2.png" alt="" border="0"></a><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://dericbownds.net/uploaded_images/Spring4.png"><img style="margin: 0px auto 10px; display: block; text-align: center; cursor: pointer; width: 200px;" src="http://dericbownds.net/uploaded_images/Spring4.png" alt="" border="0"></a><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://dericbownds.net/uploaded_images/Spring3.png"><img style="margin: 0px auto 10px; display: block; text-align: center; cursor: pointer; width: 200px;" src="http://dericbownds.net/uploaded_images/Spring3.png" alt="" border="0"></a><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://dericbownds.net/uploaded_images/spring6.png"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 200px;" src="http://dericbownds.net/uploaded_images/spring6.png" alt="" border="0"></a><br /><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://dericbownds.net/uploaded_images/spring5.png"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 200px;" src="http://dericbownds.net/uploaded_images/spring5.png" alt="" border="0"></a>Deric Bowndstag:blogger.com,1999:blog-22093933.post-16150701696776487202007-05-23T08:00:00.000-05:002007-05-23T08:01:03.448-05:00Schermer on happiness - science and historyAn essay by Michael Schermer in the March 2007 issue of the Scientific American (<a href="http://dericbownds.net/uploaded_images/Schermer_happiness.pdf">PDF here</a>), briefly notes several recent books on happiness research and emphasizes the point that assumptions about what constitutes happiness vary over time. Take sex:<br /><blockquote>"A century ago, an average man who had not had sex in three years might have felt proud of his health and forbearance, and a woman might have praised herself for the health and happiness benefits of ten years of abstinence."</blockquote>Deric Bowndstag:blogger.com,1999:blog-22093933.post-17783166449532250002007-05-23T08:00:00.000-05:002007-05-23T07:59:56.151-05:00Visual IllusionsHere are two sites of stimulating illusions that I return to when I need a moment of relief. <a href="http://www.michaelbach.de/ot/">One</a> is by Michael Bach, the <a href="http://www.scientificpsychic.com/graphics/">other</a> is a part of the Scientific Psychic website.Deric Bowndstag:blogger.com,1999:blog-22093933.post-89702154872077284822007-05-22T05:55:00.000-05:002007-05-22T11:43:02.504-05:00Deric, a vacation, and thinking about MindBlog-opps!(NOTE - somehow the comments got turned off for this post initially, I'm grateful to a reader for pointing this out to me.)<br />I will be in Mexico for a week, starting Wednesday May 23, to attend my son's wedding, and am uncertain whether it will be practical to continue doing blog postings. This potential hiatus makes me pause for a moment to mull over how this whole blog trip is going. I am a relative newbie to the business, having started this up in Febuary of 2006. On reading about the blog phenomenon in the New York Times, I thought to myself "Here I am doing all this reading and scanning about mind and brain stuff for my own pleasure, and also to prepare the occasional lecture...I might as well make the small extra effort of putting it online in case others are interested." I meant it to be an optional, casual activity. I also meant it to be fun, i.e. , not like work. For a retired academic type, with major obsessive compulsive tendencies, that is easier said than done. I've become addicted to the daily ritual, as well as paying the Feedburner.com site a few bucks a month to show me that by now that there are approximately 170 daily subscriptions to the site's RSS feed, and 350-400 views of individual postings (this is more people that I was reaching in my live university lectures). I have no idea how this compares with other sites out there that deal with similar stuff (and there are a lot of them - I don't look at them that much because I'm too busy reading the new material I find in the literature...).<br /><br />I do get the occasional email and comment - there have been a few "thank you for doing this" emails that I really appreciated - but in general I'm surprised at how little feedback there is. I scratch my head and think, "I guess this thing is keeping me off the streets; yet, is it worth the energy I'm putting into it? Would getting out of the lockstep of two posts/day increase the perceived fun/work ratio and open up time for more thoughtful writing?" No resolution on any of this.... but, I thought I would put down these wandering thoughts. Comments welcomed.Deric Bowndstag:blogger.com,1999:blog-22093933.post-59775536760281256422007-05-22T05:45:00.000-05:002007-05-22T05:45:27.394-05:00Genetic basis for vulnerability to drug addiction.Yacubian et al.(<a href="http://www.pnas.org/cgi/content/full/104/19/8125">link to full text</a>) demonstrate that human genetic variations that alter dopamine neurotransmission involved in reward pathways correlate with change in sensitivity to rewards and also with activity in the ventral striatum reward system. The data suggest a potential genetic basis for drug vulnerability. Here is their abstract:<br /><blockquote>Reward processing depends on dopaminergic neurotransmission and is modulated by factors affecting dopamine (DA) reuptake and degradation. We used fMRI and a guessing task sensitive to reward-related activation in the prefrontal cortex and ventral striatum to study how individual variation in genes contributing to DA reuptake [DA transporter (DAT)] and degradation [catechol-o-methyltransferase (COMT)] influences reward processing. Prefrontal activity, evoked by anticipation of reward irrespective of reward probability and magnitude, was COMT genotype-dependent. Volunteers homozygous for the Met allele, associated with lower enzyme activity and presumably greater DA availability, showed larger responses compared with volunteers homozygous for the Val allele. A similar COMT effect was observed in the ventral striatum. As reported previously, the ventral striatum was also found to code gain-related expected value, i.e., the product of reward magnitude and gain probability. Individual differences in ventral striatal sensitivity for value were in part explained by an epistatic gene–gene interaction between COMT and DAT. Although most genotype combinations exhibited the expected activity increase with more likely and larger rewards, two genotype combinations (COMT Met/Met DAT 10R and COMT Val/Val 9R) were associated with blunted ventral striatal responses. In view of a consistent relationship between reduced reward sensitivity and addiction, our findings point to a potential genetic basis for vulnerability to addiction.</blockquote>Deric Bowndstag:blogger.com,1999:blog-22093933.post-2412284532863762012007-05-22T05:40:00.000-05:002007-05-22T05:42:57.736-05:00Fantastic Dances...Three of them, by Shostakovitch, which I recorded on my Steinway B at Twin Valley, Middleton Wisconsin.<br /><br /><object width="425" height="350"><param name="movie" value="http://www.youtube.com/v/Xkhw62PHEno"></param><param name="wmode" value="transparent"></param><embed src="http://www.youtube.com/v/Xkhw62PHEno" type="application/x-shockwave-flash" wmode="transparent" width="425" height="350"></embed></object>Deric Bowndstag:blogger.com,1999:blog-22093933.post-7424736150012810192007-05-21T06:28:00.000-05:002007-05-21T06:28:17.792-05:00Brain imaging that reflects moral responsibility.<a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://dericbownds.net/uploaded_images/RTPJ.jpeg"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 320px;" src="http://dericbownds.net/uploaded_images/RTPJ.jpeg" alt="" border="0" /></a>In the common law tradition, criminal conviction depends on both <span style="font-style: italic;">actus reus</span> (a harmful consequence and <span style="font-style: italic;">mens rea</span> (the intent to harm). <a href="http://www.pnas.org/cgi/content/abstract/104/20/8235">Young et al.</a> (PDF <a href="http://dericbownds.net/uploaded_images/young.pdf">here</a>) set up an experimental test using different small stories to demonstrate that a subject's belief that he/she has caused intentional harm causes a larger increase in the activation of a region of the right temporal parietal junction (RTPJ in the figure.) than attempted harm, unknowing harm, and neutral effect.) The study suggests that moral judgments depend on the cognitive processes mediated by the RTPJ, previously associated with belief attribution, and, to a lesser extent, the PC, LTPJ, and MPFC, which compose a network of brain regions implicated in theory of mind.<br /><br />The discussion of the paper is well worth reading. Here is one clip:<br /><blockquote>The current results also reveal an asymmetry between moral judgments of incompetent criminals (whose false beliefs prevent intended harm from occurring) and unlucky innocents (whose false beliefs lead them to cause unintended harms. Judgments of incompetent criminals were harsh, made on the basis of beliefs alone, and associated with enhanced recruitment of circuitry involved in belief attribution. By contrast, unlucky innocents were not entirely exculpated for causing harm on the basis of their false beliefs. Instead of showing an increased response in brain regions associated with belief attribution, whole-brain analyses revealed recruitment of brain regions associated with cognitive conflict: right inferior parietal cortex, PC, bilateral middle frontal gyrus, and bilateral anterior cingulate sulcus. All of these regions have been implicated in cognitive conflict associated with moral dilemmas, specifically where subjects endorse emotionally salient harmful acts to prevent greater harm. Here subjects had to override judgments against harm in favor of utilitarian considerations (e.g., the greatest good for the greatest number). Analogously, in the context of unknowing harm, subjects may partially override judgments against harm to exculpate agents on the basis of their false beliefs. Moral judgment may therefore represent the product of two distinct and at times competing processes, one responsible for representing harmful outcomes and another for representing beliefs and intentions. </blockquote>Deric Bowndstag:blogger.com,1999:blog-22093933.post-35752526072884726252007-05-21T06:27:00.000-05:002007-05-21T06:27:04.665-05:00Potential drug for chronic pain?A new era in pain research may be coming. A particular class of sodium nerve channels (resistant to tetrodotoxin) are central in generating pain signals. Extensive screening for drugs that block this channel have yielded A-803467, a furan-amide. <a href="http://www.pnas.org/cgi/content/abstract/104/20/8520">Jarvis et al.</a> show that this drug attenuates neuropathic and inflammatory pain in a rat model. Chronic pain affects about 1.5 million people worldwide, and is currently treated with sodium channel blockers originally developed as anticonvulsants or antiarrhythmics. While beneficial for some patients, their clinical usefulness has been limited.Deric Bownds