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The authors examined the mechanism by which antibodies gain access to neuronal tissues to control infection. Using a mouse model of genital herpes infection, they demonstrated that both antibodies and CD4 T cells are required to protect the host after immunization at a distal site. [Nature]
Abstract | Press Release

Researchers examined the expression of CD23 in different subsets of peripheral B cells and the impact of CD23 expression on the early events of B-cell receptor activation using CD23 knockout mice. [Sci Rep]
Full Article

To date, there are no assays or methods to predict or explain variations in an individual’s level of response to influenza vaccination. Researchers measured levels of several immune cell subsets at baseline (Day 0) and at Days 3 and 28 post-vaccination using flow cytometry. [Immunology]
Full Article | Press Release

Genmab A/S announced that data on daratumumab and ofatumumab will be presented. [Press release from Genmab A/S discussing research to be presented at 21st Congress of the European Hematology Association (EHA), Copenhagen]
Press Release

Abpro announced co-development agreements with Massachusetts General Hospital and Brigham and Women’s Hospital, two of the country’s leading academic medical centers. [Abpro (Business Wire)]
Press Release

Pelican Therapeutics announced that it won a $15,245,222 million New Company Product Development Award from the Cancer Prevention and Research Institute of Texas. The award will enable Pelican to develop agonists directed at TNFRSF25, a recently discovered T cell costimulator for immuno-oncology indications. [Pelican Therapeutics (PR Newsire Association LLC)]
Press Release