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Hum 6,376

ARCADIA, CA ? Conan O'Brien will be behind the mic on Friday, just not at his desk on the set of his late-night talk show.

The funny man will call a horse race at Santa Anita under the watchful eye of long-time track announcer Trevor Denman. O'Brien will describe the second race at the host track for next month's Breeders' Cup, the richest event in thoroughbred racing.

Denman says his advice to O'Brien will be "keep it simple and try and have fun with it."