Genomes and Genes

Species

dental pellicle

Summary

Summary: A thin protein film on the surface of DENTAL ENAMEL. It is widely believed to result from the selective adsorption of precursor proteins present in SALIVA onto tooth surfaces, and to reduce microbial adherence to the TEETH.

Top Publications

Roles of salivary proteins in the adherence of oral streptococci to various orthodontic brackets

..However, salivary pellicles decreased the binding of S. mutans. Collectively, salivary pellicles were found to play a significant role in the initial adhesion of oral streptococci to orthodontic brackets...

..This review summarizes the present state of research on enzymes and their functions in the dental pellicle. Theoretically, all enzymes present in the oral cavity could be incorporated into the pellicle, but ..

..Fragments present in the AEP show a predominance of cleavage points located at Arg, Tyr and Lys residues. Obtained data suggest that proteolytic activity could influence AEP formation and composition...

Intrinsic enzymatic crosslinking and maturation of the in situ pellicle

..It has been supposed that the pellicle undergoes maturation after protein adsorption. The aim of the present study was to investigate enzyme activities with an impact on intrinsic maturation processes in in situ formed pellicles...

..These are potentially suited as templates for the design of a new generation of antibiotics, since they kill a broad spectrum of microorganisms, while hardly evoking resistance, in contrast to the classical antibiotics...

Protective effect of the in situ pellicle on dentin erosion - an ex vivo pilot study

..To elucidate the first colonizers within in vivo dental biofilm and to establish potential population shifts that occur during the early phases of biofilm formation...

Protective effect of the dental pellicle against erosive challenges in situ

A T HaraFaculty of Dentistry of Piracicaba, State University of Campinas, Piracicaba, SP, BrazilJ Dent Res 85:612-6. 2006

The acquired dental pellicle helps prevent erosion, but the protection level is unknown. This in situ study tested whether a two-hour pellicle protects against different erosive challenges by orange juice...

Exposure time of enamel and dentine to saliva for protection against erosion: a study in vitro

..In conclusion, site-dependent differences of buccally and lingually in vivo formed 24-hour pellicles have minor importance concerning the pellicle-induced protection of the enamel surface against erosive changes...

Hexametaphosphate effects on tooth surface conditioning film chemistry--in vitro and in vivo studies

..Polyphenols are expected to have antibacterial properties. Cistus is a tea rich in polyphenols. The aim of the present in situ study was to investigate the effect of Cistus-tea on the pellicle and on the initial oral biofilm...

Action of agents on glucosyltransferases from Streptococcus mutans in solution and adsorbed to experimental pellicle

..These findings suggest the involvement of specific adhesins in bacterial recognition of many adsorbed salivary proteins and glycoproteins...

Enamel erosion in dietary acids: inhibition by food proteins in vitro

C A HemingwayDepartment of Oral and Dental Science, University of Bristol, Bristol, UKCaries Res 44:525-30. 2010

..The citrate ion may play an active stabilising role, since erosion reduction was less in the other acids. In conclusion, casein and, to a lesser extent, ovalbumin show promise as potential anti-erosive additives to drinks...

Efficacy and mechanisms of non-antibacterial, chemical plaque control by dentifrices--an in vitro study

..It is the aim of this paper to analyze in vitro detachment of co-aggregating oral actinomyces and streptococci from pellicle surfaces by dentifrice supernates and to study subsequent de novo streptococcal deposition...

Adsorption of salivary and serum proteins, and bacterial adherence on titanium and zirconia ceramic surfaces

..To investigate and compare the protective impact of the in situ formed salivary pellicle on enamel and dentine erosion caused by different acids at pH 2.6...

Moderation of oral bacterial adhesion on saliva-coated hydroxyapatite by polyaspartate

Y H GuanUniversity of Sheffield and Boots National Centre for Applied Research into Oral Health, and Department of Oral Health and Development, School of Clinical Dentistry, Sheffield S10 2TA, UKJ Appl Microbiol 94:456-61. 2003

..Synthetic sodium alpha,beta-polyaspartate (PA) has been investigated as a moderator of adhesion and the subsequent biofilm formation by oral bacteria...

Surfactive and antibacterial activity of cetylpyridinium chloride formulations in vitro and in vivo

..To compare effects of three cetylpyridinium chloride (CPC) formulations with and without alcohol and Tween80 on physico-chemical properties of salivary pellicles, bacterial detachment in vitro and bacterial killing in vivo...

..Neither is there consensus as to how effective fluorides are in preventing the progression of erosive lesions, or how the chemical and structural factors of tooth tissue in general might modify this pathological process...

The effects of milk and kappa-casein on salivary pellicle formed on hydroxyapatite discs in situ

..This suggests that the examined PAc's are not relevant as far as the initial adhesion of Streptococcus mutans to the tooth's surface is concerned, as defined by the similarities in the results for healthy and affected individuals...

Influence of biosurfactant on interactive forces between mutans Streptococci and enamel measured by atomic force microscopy

..Some proteins of innate defense system have bactericidal or bacteriostatic effects; some can cause aggregation of oral bacteria resulting in their increased clearance from oral cavity...

Adhesion of Streptococcus mutans to different types of brackets

William PapaioannouDepartment of Preventive and Community Dentistry, University of Athens Dental School, Athens, GreeceAngle Orthod 77:1090-5. 2007

..To examine the difference in the adhesion of Streptococcus mutans to three different types of orthodontic brackets and the effect of the presence of an early salivary pellicle and Streptococcus sanguis on adhesion...

Influence of oral detergents and chlorhexidine on soft-layer electrokinetic parameters of the acquired enamel pellicle

..Dental caries is an infectious disease, and it affects 90 percent of late adolescents and young adults in the United States. It is a complex disease that occurs along the interface between the dental biofilm and the enamel surface...

..mutans was 2 times higher in than S. mitis (3.8) and slightly higher than S. sanguis (7.2). These findings may provide useful information regarding the mechanism of early biofilm formation by streptococci on the tooth surface...

Protective effect of different tetrafluorides on erosion of pellicle-free and pellicle-covered enamel and dentine

A WiegandClinic for Preventive Dentistry, Periodontology and Cariology, University of Zurich, Zurich, SwitzerlandCaries Res 42:247-54. 2008

..Tetrafluoride solutions, especially 1% TiF(4), could decrease dental erosion, but were more effective on dentine than on enamel...

The anti-adherence effect of Piper betle and Psidium guajava extracts on the adhesion of early settlers in dental plaque to saliva-coated glass surfaces

..It is therefore suggested that the plant extracts, in expressing their anti-adherence activities, could have altered the hydrophobic nature of the bonding between the bacteria and the saliva-coated glass surfaces...

Bacteria-binding plasma proteins in pellicles formed on hydroxyapatite in vitro and on teeth in vivo

Previous studies on dental pellicle formation and bacterial adherence have focussed on saliva and its components. The tooth surface is, however, also exposed to the plasma-derived crevicular fluid. In the present study, (i)...

[Non mucin proteins of saliva with high homology of polypeptide chains]

A Zalewska

Postepy Hig Med Dosw 55:733-54. 2001

..Most of them are able to inhibit the formation of dental calculus and control the calcium phosphate homeostasis...

..To investigate the effects of 5 kinds of natural medicine such as Radix et Rhizoma Rhei on the adherence of Streptococcus mutans to salivary acquired pellicle, and to screen effective natural medicines for the prevention of caries...

Probiotic bacteria affect the composition of salivary pellicle and streptococcal adhesion in vitro

..The aim of this study was to investigate in vitro if the probiotic bacteria used in commercial products affect the protein composition of the salivary pellicle and the adherence of other oral bacteria...

Experiments on in vivo biofilm formation and in vitro adhesion of Candida species on polysiloxane liners

..Microorganisms may colonise polysiloxane soft liners leading to bio-deterioration. The aim of this study was to investigate in vitro adhesion and in vivo biofilm formation of Candida species on polysiloxane surfaces...

..Phenotypic variations in milk and saliva glycosylation may explain the inhibitory capacity and possibly affect susceptibility to colonization by S. mutans in childhood...

The cariogenic dental biofilm: good, bad or just something to control?

Mark Steven WolffDepartment of Cariology and Comprehensive Care, College of Dentistry, New York University, New York, NY 10010, USABraz Oral Res 23:31-8. 2009

..Optimal management of cavitations requires early detection. This, coupled with advances in adhesive restorative materials and microsurgical technique, will allow the tooth to be restored with minimal destruction to nearby healthy tissue...

An in vitro study on the anti-adherence effect of Brucea javanica and Piper betle extracts towards oral Candida

..The adherence of Candida to mucosal surfaces is the initial step for successful invasive process of the oral cavity. The study aimed to investigate the effect of two plant extracts on the non-specific and specific bindings of oral candida...

Erosion--chemical and biological factors of importance to the dental practitioner

Domenick T ZeroDepartment of Preventive and Community Dentistry, Indiana University School of Dentistry, Indianapolis 46202, USAInt Dent J 55:285-90. 2005

..Frequent application of high concentration topical fluoride may be of some benefit in preventing further demineralisation and increase the abrasion resistance of erosion lesions...

..We show that P. gingivalis strains with genotype I and II of FimA are efficient in interaction with saliva or S. gordonii. This work highlights the important role of FimA type I and II in P. gingivalis attachment to oral surfaces...

..Experimental parameters must be chosen with care to ensure that the problem is investigated in an appropriate mode at standardised conditions and with adequate measuring systems to allow prediction of clinical outcomes...

Effect of water storage of E-glass fiber-reinforced composite on adhesion of Streptococcus mutans

J TannerInstitute of Dentistry, and Biomaterials Research, University of Turku, FinlandBiomaterials 22:1613-8. 2001

..The results of this in vitro study suggest that in order to avoid the possible increase in S. mutans adhesion, the reinforcing glass fibers should be covered with the matrix polymer of the composite...

Research Grants4

..Our third objective is to evaluate the complement-mediated neutralization of infectious HIV-1 particles by paired combinations of the truncated bi-specific antibodies. [unreadable] [unreadable] [unreadable]..

..Our eventual goal (in a future application) is to determine caries risk well before the onset of lesions and to identify those who are caries active short of cavitation or even white spot formation. ..