This blog is devoted to the discussion of all aspects of synthetic organic chemistry and related sciences. Curly Arrow is run by a synthetic organic chemist based in Copenhagen, Denmark. Contributions from readers are always welcome and should be emailed to curlyarrow@gmail.com

Apologies to RTHL for deleting his/her comment by mistake. Here it is:

"this chemical is crazy hard to dissolve for whatever reason, I tried standard acylation chemistry with this guy and was shocked at how much DCM, Et3N, and eventually 3 hours in, MeCN, i needed to actually get it in solution before i added the acyl chloride"