The Southern California locations where Agents of S.H.I.E.L.D. is filmed.

Episode 11, of Season 2 ("Aftershocks")

27:00: As part of a S.H.I.E.L.D. sting, Lance Hunter has "rescued" Hydra operative Bakshi from aS.H.I.E.L.D.
transport, under the pretense that he has himself been hired by Hydra as a mercenary. Bakshi believes him.

In this scene, Hunter & Bakshi have stopped somewhere outside, near a bridge.

Bakshi places a call to Bloom, and after he does, Hunter pulls a gun and
pretends
that he is about to execute Bakshi on orders from a Hydra faction.

But then he allows himself
to be "bribed" by Bakshi to drive him to his Hydra friends, instead.

This scene was shot on Mesquit Street (near 650 Mesquit), in downtown Los Angeles,
under the support columns of the 6th Street
bridge (on the west side of the L.A. River).

Now, let's take a closer look at those shots:

In the shot above, the camera is looking south up Mesquit Street, from under the bridge.
(The building, with the window, seen behind them is at 600 Santa Fe.)

In the shot above, they are standing near the fence on the east side of a parking lot east of Mesquit,
just west of the railroad tracks. The camera is looking
east, with the passing train heading south.
Here is a Google StreetView of the area.

The photos on this
page are stills from "Agents of S.H.I.E.L.D."
(which you can buy here) and are copyright ABC/Disney/Marvel.