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The following paintings were part of a single altarpiece. Complete in its original frame, it is one of only three large Italian Renaissance pictures in the National Gallery to retain their original frames. The gilded frame is striking for its 'all'antica' form and rich variety of colour simulating porphyry, granite and marble.

It was commissioned in March 1490 by Ranuzio Ottoni, Lord of Matelica, and Giorgio di Giacomo, guardian of the local Franciscan convent.