Main research programs concern :- Localized cancers such as those of Prostate, Brain (glioblastoma), Breast, using interstitial (focal) laser therapies- Diffused cancers of the peritoneal cavity (carcimatosis), of the pleural cavity (mesothelioma) using intra-cavitary laser therapies.

In Dermatology, PDT is used to treat Actinic Keratosis, which is a widespread precancerous skin disease.

Research is carried out using ONCO-THAI technical platforms (hardware and software) based on mathematical modeling, imaging, and simulation development tools. These platforms are constantly im-proved, and are extensively used for pre-clinical or clinical studies and during technology transfer to industrial partners.

NeuroPDT

With a rising incidence up to 5 new cases each year per 100,000 people (4000 new cases per year in France), glioblastoma (GBM) is the third cause of death by cancer in young adults population. It is an incurable tumor whose median survival is less than 18 months. This oncology domain remains of great interest in both preclinical and clinical research. The stan­dard treatment is based on sur-gical resection followed by brain irradiation associated with chemo-therapy.

PCaFLA

Prostate cancer (PCa) remains the most commonly occurring malignancy among men in the developed countries. For its support, research is undertaken in different aspects including diagnosis, prognostication, and treatment.

MesoPDT

Malignant pleural mesothelioma (MPM) is an aggressive serosal tumor of the pleura. Its main aetiological agent is an exposure to asbestos fibers, mostly work-related, and the disease appears after a latency of 30 to 40 years after initial exposure.

DermatoPDT

Actinic keratoses (AKs) are erythematous and squamous skin lesions, rough to the touch, present on sun-exposed areas (face, neck, scalp, back of hands, legs and forearms). They reach more readily the elderly, light phototype, having worked out. They affect the quality of life because of their impact on the body schema; they are sometimes painful and sometimes hemorrhagic tendency in contact. Moreover these lesions can evolve into invasive squamous cell carcinoma.