We invite scientists to participate in proposing for Multi-Cycle Treasury programs using the Hubble Space Telescope (HST). The telescope and its instruments were built under the auspices of the National Aeronautics and Space Administration (NASA) and the European Space Agency (ESA). Management of HST’s scientific program is carried out by the Space Telescope Science Institute (STScI). Up to 750 orbits per cycle, starting in Cycle 18, will be available for MCT Programs. The intent is to provide astronomers with the opportunity to tackle key scientific questions that cannot be fully addressed through the standard time allocation process.