06/29/26The Heath Group welcomes its newest member Alice Hsu, a graduate student in Bioengineering!

05/19/16Jim gave an interview with ecancertv about neoantigens and cancer immunotherapy at AACR 2016. See it here!

04/12/16Wei's work on single-cell phosphoproteomics and targeted combination therapy in glioblastoma was published in Cancer Cell and featured in the current issue! Nataly's paper on the identification of tumor-specific unbalanced processes has also been published in Journal of Physical Chemistry B!

10/23/15A big congratulations to our high school students John Heath, Joseph (Jun Hyuk) Oh, and Emma Winson, who have advanced as Regional Finalists in the 2015 Siemens Competition! John, Joseph, and Emma spent their summer researching KRAS under the mentorship of Ryan Henning. We're rooting for you!

9/28/2015Dr. William Dichtel (a former postdoc who is an Associate Professor at Cornell University) has been selected for the prestigious MacArthur Fellowship! CONGRATULATIONS!

9/17/2015Samir and Arundhati's paper on the general epitope targeting strategy with macrocyclic peptides has been
published in Angewandte Chemie Int. Ed.. Congrats to them and the rest of the capture agents subgroup!

6/25/2015Congratulations to alumni Dr. Nataly Kravchenko-Balasha who is a new assistant professor at The Hebrew University of Jerusalem!

5/28/2015Congratulations to Alex and Kaycie! Alex is graduating and starting an Insight Data Science Fellowship next week, and Kaycie is starting her post-doctoral position at EPFL in Switzerland next week. Good luck with everything guys, we'll miss you!

4/29/2015Blake's paper on using the tertiary structure of Botulinum toxin to assemble an inhibitor was just published in Angewandte Chemie.

4/16/2015Congratulations to Liz for receiving an NSF fellowship!

4/13/2015Kaycie's paper on epitope targeting the E17K point mutation was just published in Nature Chemistry and featured on the Caltech homepage!

3/19/2015Min's paper on quantifying metabolites from single cells was just published in JACS.

Research

Predictive Cancer Therapy

Engineered T Cell Immunotherapy

Department of Defense Capture Agents

Cancer Capture Agents

Developing World Diagnostics

Our group works on applications of chemical physics to fundamental biology and translational medicine - with a clear focus on oncology. We are comprised of a diverse, talented, and highly motivated group of graduate students and postdoctoral researchers. Our graduate students come from the physical, organic, and inorganic areas of Chemistry, Chemical Engineering, and from Physics, the Caltech/UCLA joint M.D./Ph.D. program, Bioengineering, Biology, and Materials Science. Our postdoctoral researchers have similarly diverse backgrounds.

Furthermore, we collaborate extensively with groups at Caltech, groups within the UCLA medical school, and groups in Seattle, Europe, Israel, and South Korea. Our labs occupy about 60% of the basement level of the Noyes Laboratory of Chemical Physics, as well as a small laboratory at UCLA devoted to translational medicine.

One thing that draws our research projects together is that we focus on the fundamental scientific bottlenecks that, if solved, can provide keys toward solving much larger problems. Those problems can be in energy conversion technologies, translational medicine, or basic oncology studies. We believe in working hard, playing hard, and that our science should be fun.

The Heath group is always looking for talented and passionate scientists interested in investigating the interface between chemical physics and biology.