Over the past several years there has been increasing reports of JAK inhibitors being used to treat recalcitrant alopecia areata with excellent results in the majority of patients. Currently it is being explored as a potential topical treatment option for treating alopecia areata as well. Overall patients and JAK inhibitors do well with minimal to no side effects but there are portentially serious medical side effects that can occur. Currently, it is not covered by insurance nor FDA approved for alopecia areata. Hopefully, in the near future with more positive data, it will be approved and be an important new treatment option for patients with this devastating hair loss condition.