major enzyme for removal of deaminated cytosine outside of replication foci, with SMUG1 acting as a broad specificity backup

EXPRESSION

Type

constitutive of

expressed in

(based on citations)

organ(s)

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

N-terminal domain contains binding motifs for both proliferating cell nuclear antigen (PCNA) and replication protein A (RPA1) , and N-terminus interacts with the active site of the enzyme and with chromatin