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FBI agents executed search warrants at Pain Management Associates locations in Greenville, Easley and Spartanburg, said Don Wood, a spokesman for the FBI field office in Columbia. He would not disclose the nature of the search warrants and declined to comment further.

"We've got multiple agencies out there working together," he said.

The entrance to the Pain Management Associates office on Grove Road in Greenville was taped off, a truck was parked in front of the door and a couple of agents were standing outside Tuesday afternoon.

An employee at the office declined to comment and a call to Pain Management Associates' Greenville office was not immediately returned.

This is not the first run-in with authorities for the business, which specializes in "painful conditions of the back and neck as well as other chronic pain problems," according to its website.

One of the doctors at Pain Management Associates, Blake Leche, and Amanda Leche, who was employed as a physician assistant at the time, each have five drug-related charges pending against them in Greenville County from June, according to arrest warrants obtained from the South Carolina Department of Health and Environmental Control.

Blake Leche's medical license was temporarily suspended in June and then reinstated in July, with restrictions on his ability to handle medication and supervise certain employees, according to State Board of Medical Examiners for South Carolina records.

Amanda Leche's physician assistant license was also suspended in June, but she has not been reinstated in South Carolina, according to State Board of Medical Examiners records.

You can connect with Daniel on Twitter @danieljgross and Gabe @gabe_cavallaro.