BPC systems are cost-effective alternatives to conventional stainless steel systems. They employ a novel design approach that helps increase shop-floor productivity. BPC components are readily integrated into a variety of high-performance systems for all steps in the production of biologics.

Definitions and applications for BPCs

The three main types of BPCs are highlighted below, which are Thermo Scientific 2D Labtainer and 3D Productainer BPCs, and tank liners. Specialty BPCs are also available for specific applications and use in bioprocess equipment.

2D Labtainer BPC systems

This is the design for small, simple BPCs from 50 mL to 50 L. Labtainers are produced from two sheets of film that are heat-sealed around the perimeter to form a pillow-shaped chamber. The ports are heat-sealed into the end seal or onto one of the chamber’s film panels.

3D Productainer BPC systems

This design is used for larger and more complicated BPCs. A square tube is formed by heat-sealing 4 sheets of film together. Top-, and bottom-porting options are available in a range of sizes from 50 L to 5000 L, with a greater degree of chamber complexity.

Tank Liner BPC systems

This design is used for non-sterile operations including mixing and waste collection. Tank liners remove the need for tank cleaning and help reduce cycle times. Tank liners are optimized for use with Thermo Scientific drums and cylindrical tanks.

The main components of a BPC chamber are the ports that enable tubing to be attached to the chamber. There are a number of different port designs depending on the type of chamber.

All BPC chambers and related components are produced in an ISO 7–certified cleanroom at our manufacturing facilities. Additional components are then attached to the BPC chamber to produce a complete BPC. BPC assembly is a process that provides the ability to produce customized BPC assemblies for all operations in the biologics or vaccines workflow. Thermo Scientific fluid transfer assemblies are also produced to complement BPC systems. Final assembly is done under the same controlled environment and to the same level of quality.

Each lot of BPCs is 100% visually inspected against product specifications, and packaged and sealed in two independent outer dust covers while still in the ISO 7–certified area. They are then placed in cardboard cartons labeled with product and lot identification.

The three main types of BPCs are highlighted below, which are Thermo Scientific 2D Labtainer and 3D Productainer BPCs, and tank liners. Specialty BPCs are also available for specific applications and use in bioprocess equipment.

2D Labtainer BPC systems

This is the design for small, simple BPCs from 50 mL to 50 L. Labtainers are produced from two sheets of film that are heat-sealed around the perimeter to form a pillow-shaped chamber. The ports are heat-sealed into the end seal or onto one of the chamber’s film panels.

3D Productainer BPC systems

This design is used for larger and more complicated BPCs. A square tube is formed by heat-sealing 4 sheets of film together. Top-, and bottom-porting options are available in a range of sizes from 50 L to 5000 L, with a greater degree of chamber complexity.

Tank Liner BPC systems

This design is used for non-sterile operations including mixing and waste collection. Tank liners remove the need for tank cleaning and help reduce cycle times. Tank liners are optimized for use with Thermo Scientific drums and cylindrical tanks.

The main components of a BPC chamber are the ports that enable tubing to be attached to the chamber. There are a number of different port designs depending on the type of chamber.

All BPC chambers and related components are produced in an ISO 7–certified cleanroom at our manufacturing facilities. Additional components are then attached to the BPC chamber to produce a complete BPC. BPC assembly is a process that provides the ability to produce customized BPC assemblies for all operations in the biologics or vaccines workflow. Thermo Scientific fluid transfer assemblies are also produced to complement BPC systems. Final assembly is done under the same controlled environment and to the same level of quality.

Each lot of BPCs is 100% visually inspected against product specifications, and packaged and sealed in two independent outer dust covers while still in the ISO 7–certified area. They are then placed in cardboard cartons labeled with product and lot identification.