Multi-Scale In Vivo Systems Analysis Reveals the Influence of Immune Cells on TNF-α-Induced Apoptosis in the Intestinal Epithelium

Ken S. Lau,

Affiliations:
Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America,
Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America,
Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America,
Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America,
Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America,
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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Virna Cortez-Retamozo,

Affiliation:
Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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Sarah R. Philips,

Affiliations:
Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America,
Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America,
Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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Mikael J. Pittet,

Affiliation:
Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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Douglas A. Lauffenburger,

Affiliations:
Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America,
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Affiliations:
Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America,
Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America,
Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America,
Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America