Anti-alpha-gal epitope [m86]

Clone Number: m86Description: Recombinant monoclonal antibody to alpha-gal epitope. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma m86.
Alternative Name(s) of Target: Gal-alpha-1 – 3Gal-beta-1 – 4GlcNAc-R
Immunogen: Rabbit red cells injected into alpha 1,3 galactosyltransferase knock-out mice.Specificity: This antibody binds to the alpha-gal epitope on glycoproteins and glycolipids.Application Notes: This antibody binds to the alpha-gal epitope found on many glycoproteins and glycolipids of non-primate mammalis, prosimians and New World monkeys. Antibodies agains the alpha-gal epitopes occur naturally in Old World monkeys, apes and humans, and induce xenograft rejection from non-primate animals.Antibody First Published in: Chen, Radic and Galili Genes coding evolutionary novel anti-carbohydrate antibodies: studies on anti-Gal production in alpha 1,3 galactosyltransferase knock out mice. Mol Immunol. 2000 Jun;37(8):455-66. PMID:11090880Note on publication: Describes the generation and characterization of anti-gal epitope antibodies raised in alpha 1,3 galactosyltransferase knock-out mice.
Reviews: No reviews available for this antibody yet. Be the first to submit a review at pAbmAbs and enter into their monthly prize draw.