"The LCP Mosquito is our workhorse instrument for the accurate and reliable dispensing of sub-microliter droplet from aqueous and LCP solutions. Reproducibility is key to what we do and the mosquito certainly delivers with excellent speed. Service support is critical to ensuring maximum use of the instrument and the team at TTP is extremely flexible and deliver to our high expectations."

"The Mosquito LCP have definitely taken protein crystallization to a higher level in our laboratory. It is an amazing high quality precision instrument that combines high throughput with ease of use. It makes a great couple with the humidity chamber added, reducing small drop evaporation considerably which previously was a challenge in our lab.
When protein amounts are scarce or we need to add small amounts of seed stock, additives or detergents its repetitive low volume capabilities are simply amazing. The ability to setup multi drop experiments is very convenient and it is easy to add new plates. The software is intuitive to use and its versatile scripting capabilities make it easy to script both simple and advanced programs.
It is really easy for everyone to work with. It is reliable, fast and robust and is ready to use within minutes, no more liquid-to-liquid interaction and time consuming wash cycles.
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"We decided in 2013 to add to our HTP protein crystallography facility at EMBL unit in Hamburg, Germany, the Mosquito-LCP instrument. The main target of the Hamburg Unit is the structural and functional characterization of proteins and other macromolecules using synchrotron X-ray radiation. In this context, the Mosquito-LCP instrument enables our users to explore and screen a large number of crystallization conditions in an efficient and reliable manner. The acquisition of the mosquito-LCP contributed significantly to the quality of our services. EMBL’s decision to integrate TTP Labtech equipments underlines their outstanding performance - a driving force in the progress of science."

"The mosquito® LCP (TTP LabTech) is very easy to use and user friendly. It is faster and reliable, less maintenance is required. It works like a charm. I am very glad that I bought it for our crystallization lab, especially working with membrane proteins one cannot miss it for LCP setups. It is also very useful for seeding techniques as well."

Description

mosquito® LCP.

mosquito LCP is the ultimate tool for membrane protein crystallisation. It overcomes the common problems encountered with accurately dispensing the highly viscous LCP mixture used in membrane protein crystallisation. It allows you to fully automate LCP set-ups accurately and repeatedly. mosquito LCP allows you to dispense lipidic cubic phase (LCP) volumes as low as 25 nL, while automated calibration of syringe and pipette positioning ensures precise drop-on-drop placement to facilitate automated imaging. It combines an automated syringe dispenser and the mosquito pipetting head (as used in mosquito Crystal) into one compact crystallisation robot capable of highly accurate, precise and rapid automated plate set-ups.

TTP Labtech also offers additional components to enhance your membrane protein crystallisation screening, such as an active humidity chamber and an automated mixer for preparing LCP.

The benefits of mosquito LCP include:

versatility – ability to set up both LCP and all traditional protein crystallisation experiments with just one instrument