3. The Family Guy

1999-2002, 2005-present For some reason, The Family Guy has been canceled twice, only to return to the airwaves based on skyrocketing DVD sales and venomous public outcries. The brainchild of Seth MacFarlane, The Family Guy is about a dysfunctional Rhode Island family of losers who are constantly ridiculed by Stewie Griffin, the diabolical baby who dreams of world domination and speaks with an upper-class British accent. As a diaper-bearing intellectual, Stewie’s sarcasm rules the roost, as his relentless wit savagely attacks the stupidity, incompetence, ugliness, and laziness of the rest of the family. And then there’s Peter Griffin, the deadbeat dad who’s actually fatter, dumber, lazier, and cruder than Homer Simpson.