Featured Research

The University of Chicago has launched the first secure cloud-based computing system that enables researchers to access and analyze human genomic cancer information without the costly and cumbersome infrastructure normally needed to download and store massive amounts of data.

The University of Chicago has launched the first secure cloud-based computing system that enables researchers to access and analyze human genomic cancer information without the costly and cumbersome infrastructure normally needed to download and store massive amounts of data.

Related Articles

The Bionimbus Protected Data Cloud, as it is called, enables researchers who are authorized by the National Institutes of Health (NIH) to access and analyze data in The Cancer Genome Atlas (TCGA) without having to set up secure, compliant computing environments capable of managing and analyzing terabytes of data, download the data -- which can take weeks -- and then install the appropriate tools needed to perform the desired analyses.

Using technology that was developed in part by the Open Science Data Cloud, a National Science Foundation-supported project that is developing cloud infrastructure for large scientific datasets, the Bionimbus Protected Data Cloud provides researchers with a more cost- and time-effective mechanism to extract knowledge from massive amounts of data. Drawing insights from big data is imperative for addressing some of today's most vexing environmental, health and safety challenges.

"The open source technology underlying the Open Science Data Cloud enables researchers to manage and analyze the large data sets that are essential to tackling some of today's greatest challenges: from environmental monitoring to cancer genomics," said Robert L. Grossman, the director of the Open Science Data Cloud Project and a professor at the University of Chicago.

Today, as the only NIH-approved cloud-based system for TCGA data, the Bionimbus Protected Data Cloud allows researchers to focus on the analysis of large-scale cancer genome sequencing, which experts believe can unlock paths to early detection, appropriate treatment and prevention of cancer.

"We are excited that the Bionimbus Protected Data Cloud is now used for cancer genomics data so that researchers can more easily work with large datasets to understand genomic variations that seem to be one of the keys to the precise diagnosis and treatment of cancer," continued Grossman.

"With funding provided by NSF's Partnerships for International Research and Education [PIRE] program, NSF has sought to narrow the gap between the capability of modern scientific instruments to produce data and the ability of researchers to access, manage, analyze and share those data in a reliable and timely manner," said NSF Program Director Harold Stolberg.

"By embracing cloud computing as a global issue, this PIRE project brings together the expertise of many researchers, not only in the United States, but worldwide. Its success in helping researchers to access and analyze important human genomic cancer information is an exciting indicator of future developments with these technologies," he said.

Megan McNerney, an instructor of pathology at the University of Chicago, used Bionimbus to analyze data that led to her discovery that gene CUX1, which acts as a tumor suppressor, is frequently inactivated in acute myeloid leukemia.

"Bionimbus was critical for my work, as it was used for all aspects of the project, including secure storage of protected data, quality control of next-generation sequencing results, alignments, expression analysis, and algorithm development," she said. "The strength of Bionimbus, however, is the support that is provided for end users, which enabled both expert and non-expert team members to use the cloud."

More From ScienceDaily

More Computers & Math News

Featured Research

Mar. 3, 2015 — By examining the forces that the segments of mosquito legs generate against a water surface, researchers have unraveled the mechanical logic that allows the mosquitoes to walk on water, which may ... full story

Mar. 3, 2015 — Major cities in the UK are falling behind their international counterparts in terms of their use of smart technologies, according to a new study. The research has found that smart cities in the UK, ... full story

Mar. 3, 2015 — To simulate chimp behavior, scientists created a computer model based on equations normally used to describe the movement of atoms and molecules in a confined space. An interdisciplinary research ... full story

Mar. 3, 2015 — Magnetic vortex structures, so-called skyrmions, could in future store and process information very efficiently. They could also be the basis for high-frequency components. For the first time, a team ... full story

Mar. 2, 2015 — The odds of picking a perfect bracket for the NCAA men's basketball March Madness championship tournament are a staggering less than one in 9.2 quintillion (that's 9,223,372,036,854,775,808), ... full story

Mar. 2, 2015 — Scientists report that they could observe experimentally the current flow along channels at the crystal surfaces of topological insulators. The channels are less than one nanometer wide and extend ... full story

Mar. 2, 2015 — Organic light emitting diodes (OLEDs), which are made from carbon-containing materials, have the potential to revolutionize future display technologies, making low-power displays so thin they'll wrap ... full story

Mar. 2, 2015 — What if one day, your computer, TV or smart phone could process data with light waves instead of an electrical current, making those devices faster, cheaper and more sustainable through less heat and ... full story

Mar. 2, 2015 — 3-D printing could become a powerful tool in customizing interventional radiology treatments to individual patient needs, with clinicians having the ability to construct devices to a specific size ... full story

Featured Videos

Forensic Holodeck Creates 3D Crime Scenes

Reuters - Innovations Video Online (Mar. 3, 2015) — A holodeck is no longer the preserve of TV sci-fi classic Star Trek, thanks to researchers from the Institute of Forensic Medicine Zurich, who have created what they say is the first system in the world to visualise the 3D data of forensic scans. Jim Drury saw it in operation.
Video provided by Reuters

Related Stories

Dec. 4, 2014 — Cloud computing and Big Data are the two top innovation hubs in ICT. Together they have the potential to become pivotal enhancers of social transformation and economic development for many years to ... full story

Sep. 8, 2010 — Researchers have developed new software that greatly improves the speed at which scientists can analyze RNA sequencing data. The software, known as Myrna, uses "cloud computing," an ... full story

June 9, 2010 — NIST has been chosen to accelerate the federal government's secure adoption of cloud computing by leading efforts to develop standards and guidelines in close consultation and collaboration with ... full story

ScienceDaily features breaking news and videos about the latest discoveries in health, technology, the environment, and more -- from major news services and leading universities, scientific journals, and research organizations.