Patient concerns about vaccine safety have risen, posing significant challenges for providers. Anti-vaccine websites, media attention to false claims about vaccine safety, and a decrease in vaccine-preventable diseases has contributed to the number of individuals who question vaccines. Providers are faced with a challenge of educating patients about the importance of vaccinations, benefits and risks of vaccinations, and vaccine safety. This section will provide you with basic vaccine safety information, assist providers with understanding patient’s hesitancy to receive vaccinations and provide resources for addressing patients’ concerns.