It worked for me like a charm. I hope it works for you if you need to run any Windows programs in LMDE3. The same procedure works for Mint 19 by changing #4 above to 'deb https://dl.winehq.org/wine-builds/ubuntu/ bionic main'

This is assuming you have a 64bit install and want working 32 & 64 prefixes, and previously added the stretch backports. This works also, no issues found so far. Have validated that I have a properly working 32 and 64 bit prefix. Personally I prefer to use q4wine (from the same repository) to manage the prefixes. It handles winetricks well, and allows for somewhat easier command line invocations of programs you've installed in a prefix using, such as:

Forgive my confusion, I'm a linux noob. Do I need to do any of the commands as listed in the previous discussion above of just what you have here listed. Also, What are the commands for in your last column and is it something I need to do also for wine to run. Lastly, you referenced a different wine, what is it and why do you prefer it? Thanks, Jeff