Polytherapy is very common in elderly patients and the usage of medicines has to be actively observed in order
to comprehend how dosages, side effects and interactions affect the quality of therapy and subsequently
patients’ lives. The aim of study was to determine the incidence of potentially inappropriate medicines (PIMs)
in elderly patients with hypertension and to examine the connection between treatment outcomes and PIMs
according to the EU(7)-PIM list. An observational cross-sectional study was carried out in Cardiology Ward at
the Department of Internal Medicine, University Hospital Dubrava. After 3 to 5 months from release,
examinees were contacted via telephone to collect additional data. Patients included in the study suffered from
hypertension, were aged 65 years or older, and were taking at least 2 medicines. PIMs were determined using
EU(7)-PIM list. Afterwards, treatment outcomes were compared to PIMs’ descriptions in EU(7)-list and
Summary of Product Characteristics. The study included 54 examinees with median age 73,8 years, who had
7,2 diagnoses and used 8,6 medicines in average. The EU(7)-list detected PIMs in 77,8% of examinees, with
pantoprazole being the most common. 88,3% of examinees reported relevant treatment outcomes occurring
after release from hospital, some of which were connected to usage of PIMs. When compared to description in
EU(7)-list, it was concluded that in 17,1% of cases PIMs provoked relevant outcomes, while that number was
significantly higher when PIMs outcomes were compared to Summary of Product Characteristics (55,3%). The
study concluded that there is high percentage of PIMs in elderly with hypertension, many of which can be
linked to undesirable treatment outcomes. EU(7)-list is a protocol which offers assistance in detecting PIMs
and achieving a favorable benefit-risk medication ratio.