The legislature failed to elect a Senator for the other seat, previously held by Jeremiah Clemens (Democratic). On November 29, 1853, Clement Claiborne Clay (Democratic) was finally elected late to the seat.

On December 20, 1852, Senator William R. King (Democratic) resigned due to poor health. On January 14, 1853, Benjamin Fitzpatrick (Democratic) was appointed to continue the term, and he was elected December 12, 1853 to finish the term.[2]