Unione Calcio Sampdoria, commonly known as Sampdoria, is an Italian association football club based in Genoa.

The club was formed in 1946 from the merger of two existing sports clubs whose roots can be traced back to the 1890s, Sampierdarenese and Andrea Doria. Sampdoria currently compete in Serie A.

The 2016–17 season will be Unione Calcio Sampdoria's 60th season in Serie A, and their 5th consecutive season in the top-flight. Having finished 15th the previous season, Sampdoria will compete in Serie A and in the Coppa Italia.