WARNING: The information on the Controlled Therapeutic Substances List does not constitute and is not a guaranty, warranty or assurance that the use of any of the therapeutic medications at the dosage and withdrawal time listed will not result in a positive post-race test. These guidelines are based upon the administration of a single medication. Combining medications or using multiple doses of single medication may significantly affect withdrawal times.

Use of this information does not lessen or relieve any trainer’s responsibility for affirming that, during a horse race, a horse is free of any therapeutic medication listed in his or her state’s racing commission rulebook, and for complying with provisions of the state racing commission’s regulations.

Owners, trainers or any other persons responsible for the care of a racehorse are strongly advised to consult a veterinarian and the state racing commission regulatory veterinarian for guidance and advice on the use and withdrawal times of all therapeutic medications, as testing methodologies may change with little or no notice. The guidelines provided in this list are not consistent with foreign regulations or laboratory methods.

Dosing Specification Single intravenous dose of acepromazine at 0.05 milligrams per kilogram

Medication Class3

Penalty ClassB

Points2 points

Time to Expunge2 years

ALBUTEROL
(Proventil®, Ventolin®)

Testing Threshold1 nanogram per milliliter of urine

Withdrawal Guideline72 hours

Dosing Specification 720 micrograms total dose intra-nasal only. Based upon 4 administrations per day

Medication Class3

Penalty ClassB

Points2 points

Time to Expunge2 years

Administration of albuterol other than via intra-nasal routes is not recommended. Use of therapeutic doses of oral albuterol even outside of the recommended withdrawal guidelines carries a substantial risk of exceeding the regulatory threshold.

Points1/2, with incremental increases of 1/2 point for each additional violation within 365 days

Time to Expunge1 year

BUTORPHANOL
(Torbugesic®)

Testing Threshold300 nanograms per milliliter of total butorphanol in urine or 2 nanograms of free butorphanol per milliliter in plasma or serum

Withdrawal Guideline48 hours

Dosing Specification Single intravenous dose of butorphanol as Torbugesic®(butorphanol tartrate) at 0.1 milligrams per kilogram

Medication Class3

Penalty ClassB

Points2 points

Time to Expunge2 years

CETIRIZINE
(Zyrtec®)

Testing Threshold6 nanograms per millititer of plasma or serum

Withdrawal Guideline48 hours

Dosing Specification 0.4 milligram per kilogram twice a day for 5 doses. Do not administer avermectins within 48 hours of racing if cetirizine is administered

Medication Class4

Penalty ClassC

Points1/2, with incremental increases of 1/2 point for each additional violation within 365 days

Time to Expunge1 year

Do not administer any avermectin drugs (including ivermectin) within 48 hours of a race if the horse has been administered cetirizine as it carries an increased risk of a concentration of cetirizine in excess of the regulatory threshold.

CIMETIDINE
(Tagamet®)

Testing Threshold400 nanograms per milliliter of plasma or serum

Withdrawal Guideline24 hours

Dosing Specification 20 milligram per kilogram twice a day for 7 doses

Medication Class5

Penalty ClassD

Points0

Time to Expunge0

CLENBUTEROL
(Ventipulmin®)

Testing Threshold140 picograms per milliliter of urine or Limit of Detection of plasma or serum

Points1/2, with incremental increases of 1/2 point for each additional violation within 365 days

Time to Expunge1 year

Horsemen are urged to avoid combining the non-steroidal anti-inflammatory drugs Flunixin (Banamine®), Ketoprofen (Ketofen®), Diclofenac (Surpass®), Firocoxib (Equioxx®) and Phenylbutazone (Butazolidin®). Only one NSAID can be present in a post-race test sample below established thresholds. If more than one NSAID is detected in a post-race sample above the established thresholds, it is considered stacking and is a medication violation subject to penalty. See NSAID Stacking under Medication Alerts.

DMSO

Testing Threshold10 micrograms per milliliter in plasma or serum

Withdrawal Guideline48 hours

Dosing Specification 2 ounces topically administered

Medication Class4

Penalty ClassC

Points1/2, with incremental increases of 1/2 point for each additional violation within 365 days

Time to Expunge1 year

FIROCOXIB
(EQUIOXX®)

Testing Threshold20 nanograms per milliliter in plasma or serum

Withdrawal Guideline14 days

Dosing Specification Oral administration of firocoxib as EQUIOXX oral paste at a daily dose of 0.1 milligram per kilogram for four days

Medication Class4

Penalty ClassC

Points1/2, with incremental increases of 1/2 point for each additional violation within 365 days

Time to Expunge1 year

Horsemen are urged to avoid combining the non-steroidal anti-inflammatory drugs Flunixin (Banamine®), Ketoprofen (Ketofen®), Diclofenac (Surpass®), Firocoxib (Equioxx®) and Phenylbutazone (Butazolidin®). Only one NSAID can be present in a post-race test sample below established thresholds. If more than one NSAID is detected in a post-race sample above the established thresholds, it is considered stacking and is a medication violation subject to penalty. See NSAID Stacking under Medication Alerts.

FLUNIXIN
(Banamine®)

Testing Threshold20 nanogram per milliliter in plasma or serum

Withdrawal Guideline32 hours

Dosing Specification Single intravenous dose of flunixin as Banamine® (flunixin meglumine) at 1.1 milligram per kilogram

Medication Class4

Penalty ClassC

Points1/2, with incremental increases of 1/2 point for each additional violation within 365 days

Time to Expunge1 year

Horsemen are urged to avoid combining the non-steroidal anti-inflammatory drugs Flunixin (Banamine®), Ketoprofen (Ketofen®), Diclofenac (Surpass®), Firocoxib (Equioxx®) and Phenylbutazone (Butazolidin®). Only one NSAID can be present in a post-race test sample below established thresholds. If more than one NSAID is detected in a post-race sample above the established thresholds, it is considered stacking and is a medication violation subject to penalty. See NSAID Stacking under Medication Alerts.

Points1/2, with incremental increases of 1/2 point for each additional violation within 365 days

Time to Expunge1 year

ISOFLUPREDONE
(Predef2x®)

Testing Threshold100 picograms per milliliter in plasma or serum

Withdrawal Guideline7 days

Dosing Specification 10 milligrams total dose subcutaneous or 20 milligrams total dose in one articular space

Medication Class4

Penalty ClassC

Points1/2, with incremental increases of 1/2 point for each additional violation within 365 days

Time to Expunge1 year

KETOPROFEN
(Ketofen®)

Testing Threshold2 nanograms per milliliter in plasma or serum

Withdrawal Guideline24 hours

Dosing Specification Single intravenous dose of ketoprofen as Ketofen® at 2.2 milligrams per kilogram

Medication Class4

Penalty ClassC

Points1/2, with incremental increases of 1/2 point for each additional violation within 365 days

Time to Expunge1 year

Horsemen are urged to avoid combining the non-steroidal anti-inflammatory drugs Flunixin (Banamine®), Ketoprofen (Ketofen®), Diclofenac (Surpass®), Firocoxib (Equioxx®) and Phenylbutazone (Butazolidin®). Only one NSAID can be present in a post-race test sample below established thresholds. If more than one NSAID is detected in a post-race sample above the established thresholds, it is considered stacking and is a medication violation subject to penalty. See NSAID Stacking under Medication Alerts.

LIDOCAINE
(Xylocaine®)

Testing Threshold20 picograms per milliliter of total 3-OH lidocaine in plasma

Withdrawal Guideline72 hours

Dosing Specification Single dose of 200 milligrams of lidocaine as its hydrochloride salt administered subcutaneously

Medication Class2

Penalty ClassB

Points2 points

Time to Expunge2 years

MEPIVACAINE
(Carbocaine®)

Testing Threshold10 nanograms total 3-hydroxymepivacaine per milliliter in urine or above Level of Detection of mepivacaine in plasma

Withdrawal Guideline72 hours

Dosing Specification Single dose of 0.07 milligrams per kilogram subcutaneously in the distal limb

Points1/2, with incremental increases of 1/2 point for each additional violation within 365 days

Time to Expunge1 year

An oral dose may be utilized but longer withdrawal time may be required to fall below the threshold. Trainers using methocarbamol orally for multiple days are encouraged to have the horse tested prior to entry.

METHYLPREDNISOLONE
(DepoMedrol®)

Testing Threshold100 picograms per milliliter in plasma or serum

Withdrawal GuidelineSee Dosing Specifications

Dosing Specification Total dose of methylprednisolone acetate suspension in one articular space. The recommended withdrawal for methylprednisolone acetate is a minimum of 21 days at a 100 milligram dose.

Medication Class4

Penalty ClassC

Points1/2, with incremental increases of 1/2 point for each additional violation within 365 days

Time to Expunge1 year

Notwithstanding the ARCI recommendation, horsemen are strongly cautioned against the use of Depo-Medrol for a horse in training. A trainer who chooses to race a horse that has been treated with Depo-Medrol despite this warning should, at his/her expense, get the horse tested prior to entry to ensure that the horse will test below the regulatory limit, which is 100 picograms per milliliter of plasma or serum. See Mid-Atlantic Advisory.

OMEPRAZOLE
(Gastrogard®)

Testing Thresholdomeprazole sulfide 10 ng per ml in serum or plasma

Withdrawal Guideline24 hours

Dosing Specification Single 2.2 gram oral dose of omeprazole as Gastrogard® for up to 4 days

Medication Class5

Penalty ClassD

Points0

Time to Expunge0

PHENYLBUTAZONE
(Butazolidin®)

Testing Threshold2 micrograms per milliliter in plasma or serum

Withdrawal Guideline24 hours

Dosing Specification Single intravenous dose of phenylbutazone at 4.0 milligrams per kilogram

Medication Class4

Penalty ClassC

Points1/2, with incremental increases of 1/2 point for each additional violation within 365 days

Time to Expunge1 year

Horsemen are urged to avoid combining the non-steroidal anti-inflammatory drugs Flunixin (Banamine®), Ketoprofen (Ketofen®), Diclofenac (Surpass®), Firocoxib (Equioxx®) and Phenylbutazone (Butazolidin®). Only one NSAID can be present in a post-race test sample below established thresholds. If more than one NSAID is detected in a post-race sample above the established thresholds, it is considered stacking and is a medication violation subject to penalty. See NSAID Stacking under Medication Alerts.

PREDNISOLONE
(Solu-delta Cortef®)

Testing Threshold1 nanogram per milliliter in plasma or serum

Withdrawal Guideline48 hours

Dosing Specification 1 milligram per kilogram orally

Medication Class4

Penalty ClassC

Points1/2, with incremental increases of 1/2 point for each additional violation within 365 days

Time to Expunge1 year

PROCAINE PENICILLIN

Testing Threshold25 nanograms per milliliter in plasma or serum

Withdrawal GuidelineFollowing entry to race

Dosing Specification Intramuscular at 17 milligrams per kilogram

Medication Class3

Penalty ClassB

Points2 points

Time to Expunge2 years

Administration must be reported to Commission

RANITIDINE
(Zantac®)

Testing Threshold40 nanograms per milliter in plasma or serum

Withdrawal Guideline24 hours

Dosing Specification 8 milligrams per kilogram twice a day for 7 doses

Medication Class5

Penalty ClassD

Points0

Time to Expunge0

TRIAMCINOLONE ACETONIDE
(Vetalog®)

Testing Threshold100 picograms per milliliter in plasma or serum

Withdrawal Guideline7 days

Dosing Specification Total dose of 9 milligram in one articular space

Medication Class4

Penalty ClassC

Points1/2, with incremental increases of 1/2 point for each additional violation within 365 days