0. DOCID:5966 SCORE: 0.00264491360970359DOCNO: 6158356OWNER: NLMSTATUS: MEDLINEQUALIFIER: surgeryQUALIFIER: surgeryQUALIFIER: surgeryAUTHOR: A Mannell APUBTYPE: Journal ArticleJOURNALTITLE: The British journal of surgery. COUNTRY: ENGLANDTITLE: Presternal gastric bypass for unresectable carcinoma of the thoracic oesophagus: a preliminary report.PUBDATE: 19800701
Presternal gastric bypass was performed on 10 African patients with unresectable carcinoma of the thoracic oesophagus. Where the cancer involved the lower third of the thoracic oesophagus the oesophagus was simply excluded. However, for cancer of the upper and middle third of the thoracic oesophagus the additional step of Roux-en-Y jejunal anastomosis to the intra-abdominal oesophagus was performed to drain away oesophageal secretions from existing or imminent tracheo-oesophageal fistulas. No patient died as a result of the operation, and 9 out of 10 patients were able to eat normally afterwards. Presternal gastric bypass is compared with other methods of palliation for unresectable carcinoma of the thoracic oesophagus.

1. DOCID:6211 SCORE: 0.0022512346080698DOCNO: 456003OWNER: NLMSTATUS: MEDLINEQUALIFIER: prevention & controlQUALIFIER: therapyQUALIFIER: complicationsAUTHOR: A D Turnbull ADAUTHOR: G Carlon GPUBTYPE: Case ReportsPUBTYPE: Journal ArticleJOURNALTITLE: Critical care medicine. COUNTRY: UNITED STATESTITLE: Airway management in the thrombocytopenic cancer patient with acute respiratory failure.PUBDATE: 19790201
Prolonged endotracheal intubation has been the preferred approach when ventilatory support is required in thrombocytopenic cancer patients, because of concern for the possible hemorrhagic complications of tracheostomy. During the past 3 years, the authors have treated over 100 patients who developed acute respiratory failure while being treated for myeloproliferative or lymphoproliferative malignancies. This experience has suggested a greater incidence of potentially lethal complications among thrombocytopenic patients with prolonged endotracheal intubation than with early tracheostomy, which is now preferred in the critical care facility of this institution. Tracheostomy using electrocautery and careful technique has been performed without complication in 35 patients whose platelet counts were as low as 5,000-20,000/mm3.

2. DOCID:7951 SCORE: 0.00202112272734703DOCNO: 7445102OWNER: NLMSTATUS: MEDLINEQUALIFIER: urineQUALIFIER: urineAUTHOR: G Cruciani GAUTHOR: D Bardella DAUTHOR: G M Fiorentini GMAUTHOR: M Marangolo MAUTHOR: L Tavolazzi LPUBTYPE: Journal ArticleJOURNALTITLE: Tumori. COUNTRY: ITALYTITLE: [Hydroxyprolinuria and bone metastases of breast cancer]PUBDATE: 19800401
The urinary excretion of Hydroxyproline (OH-P), evaluated as OH-P/creatinine ratio, has been examined in the follow up of 142 breast cancer patients. The mean value obtained in the women with bone lytic lesions, prior to treatment, was 5.3 +/- 1.9 (min. 3, max. 9), whereas in the women without bone metastases it was 1.7 +/- 0.5 (min. 0.6, max. 3), similar to the control group. The patients affected by osteoplastic lesions had a normal OH-P/creatinine ratio. The highest values of OH-P/creatinine ratio were found in women with bone marrow infiltration, ascertained by bone needle biopsy. In the group of patients with bone lytic metastases, a good correlation between changes of OH-P/creatinine ratio and response to hormonal or chemotherapeutic treatment has been observed. Therefore the OH-P/creatinine ratio could be effectively useful, with other clinical parameters, in the follow up of breast cancer patients.

3. DOCID:6776 SCORE: 0.00195112895561865DOCNO: 222741OWNER: NLMSTATUS: MEDLINEQUALIFIER: therapeutic useQUALIFIER: therapeutic useQUALIFIER: drug therapyAUTHOR: A A Maltbie AAAUTHOR: J O Cavenar JOAUTHOR: J L Sullivan JLAUTHOR: E B Hammett EBAUTHOR: W W Zung WWPUBTYPE: Clinical TrialPUBTYPE: Controlled Clinical TrialPUBTYPE: Journal ArticleJOURNALTITLE: The Journal of clinical psychiatry. COUNTRY: UNITED STATESTITLE: Analgesia and haloperidol: a hypothesis.PUBDATE: 19790701
We have previously reported 10 patient histories involving various intractable pain syndromes where the administration of Haloperidol either eliminated the need for narcotic analgesics or resulted in a significant reduction in narcotic dosage. We are presently undertaking a controlled double-blind evaluation of Haloperidol as an adjunctive treatment for intractable cancer pain. Based upon the reported clinical observations, these findings are discussed from the following aspects: 1. The isomeric similarity of Haloperidol to Meperidine. 2. Dose response between Haloperidol and analgesic effect. 3. The clinical literature regarding the use of Haloperidol for the effective withdrawal or maintenance of narcotic addicts. 4. The analgesic property as it relates to the opiate receptor.

4. DOCID:7702 SCORE: 0.00194992327971451DOCNO: 6794700OWNER: NLMSTATUS: MEDLINEDESCRIPTOR: RadiologyAUTHOR: G H Mooney GHPUBTYPE: Journal ArticleJOURNALTITLE: The British journal of radiology. COUNTRY: ENGLANDTITLE: Radiology and risk: an economist's perspective.PUBDATE: 19811001
This paper, which is an amended version of a talk given to The British Institute of Radiology at a meeting on "Dosimetry and Risks to Patients in Radiopharmaceutical Investigations", picks up the ICRP's concept of detriment and places it firmly in the framework whence it came, viz. cost-benefit analysis. It explains cost-benefit analysis (distinguishing it from cost-effectiveness analysis) and suggests various ways of trying to place a value on human life in order to use cost-benefit analysis as a practical tool of decision-making in policy areas where at least part of the benefit is to be measured in terms of lives saved. The paper suggests that it is important to decide not only who is to value life but also whose perception of risk of death are to be deemed relevant. A practical example in the use of life values is presented for the case of mammography in breast cancer screening.

5. DOCID:6694 SCORE: 0.00174707597794124DOCNO: 6798995OWNER: NLMSTATUS: MEDLINEDESCRIPTOR: ABO Blood-Group SystemQUALIFIER: isolation & purificationQUALIFIER: analysisAUTHOR: H Hattori HAUTHOR: K Uemura KAUTHOR: T Taketomi TPUBTYPE: Journal ArticleJOURNALTITLE: Biochimica et biophysica acta. COUNTRY: NETHERLANDSTITLE: The presence of blood group A-active glycolipids in cancer tissues from blood group O patients.PUBDATE: 19811201
Glycolipids were isolated from human gastric cancer tissues and normal mucosae. Sulfogalactosylceramide, ganglioside and neutral glycolipid fractions were separated by DEAE-Sephadex and silica gel column chromatography. Sulfogalactosylceramide contents were higher in the cancer tissues than in the normal mucosae. Ganglioside contents showed considerable variations but in the cancer tissues in mole percentage of ganglioside GM3 was higher than in the normal mucosae. The cancer tissues contained more neutral glycolipids than normal tissues. Glycolipids of lacto-series, including fucolipids, were markedly increased in the cancer tissues. Blood group A-active glycolipids were found in the cancer tissues from two patients with blood group O but not found in the uninvolved tissue associated with the cancer tissue.

6. DOCID:7025 SCORE: 0.00173130176812869DOCNO: 648093OWNER: NLMSTATUS: MEDLINEQUALIFIER: radiation effectsQUALIFIER: radiotherapyAUTHOR: A V Santhamma AVAUTHOR: K R Das KRPUBTYPE: Journal ArticleJOURNALTITLE: Clinical radiology. COUNTRY: ENGLANDTITLE: Clinical dosimetry of the rectum in cathetron applications for treatment of carcinoma of the uterine cavity.PUBDATE: 19780501
Rectal dose measurements have been carried out for 60 patients undergoing Cathetron therapy for the treatment of carcinoma of the uterine cervix at the Cancer Hospital, Indore. The measurements show that the maximum rectal dose occurred around 8 cm from the anal verge. In most of the cases (approximately 75%) the maximum rectal dose lies between 50 and 85% of the dose at point A. The combined biologically effective doses from intracavitary and external beam therapy regimes in this centre and the clinical complications have been compared with those of other centres. Although no immediate serious rectal complications have been observed, it is desirable to check the rectal dose using monitoring source pencils, so that the applicators and rectal retractor can be readjusted, if necessary, to minimise the dose.

7. DOCID:7522 SCORE: 0.00172466957443939DOCNO: 6770270OWNER: NLMSTATUS: MEDLINEDESCRIPTOR: MenopauseQUALIFIER: therapeutic useAUTHOR: M C Weinstein MCPUBTYPE: Journal ArticleJOURNALTITLE: The New England journal of medicine. COUNTRY: UNITED STATESTITLE: Estrogen use in postmenopausal women--costs, risks, and benefits.PUBDATE: 19800801
The cost effectiveness of estrogen use in postmenopausal women was analyzed with use of data from the medical and epidemiologic literature. Risks of endometrial cancer, uterine bleeding, and gallbladder disease were weighed against benefits associated with relief of menopausal symptoms and with prevention of osteoporosis and consequent fractures. Net effects on life expectancy are probably small in either direction, although they are likely to be positive in women with existing osteoporosis or prior hysterectomy. Treatment appears to be relatively cost effective in menopausal women with prior hysterectomy or osteoporosis but does not appear to be cost effective as a prophylactiv measure in asymptomatic women with intact uteri. For women with menopausal symptoms and intact uteri, the decision to prescribe estrogens for the individual patient and the cost effectiveness of estrogen use at the societal level depend critically on the subjective values assigned to symptomatic relief.

8. DOCID:5209 SCORE: 0.00168558652259156DOCNO: 637693OWNER: NLMSTATUS: MEDLINEDESCRIPTOR: Neoplasms, Radiation-InducedQUALIFIER: etiologyQUALIFIER: etiologyQUALIFIER: etiologyQUALIFIER: etiologyQUALIFIER: etiologyQUALIFIER: etiologyAUTHOR: V A LiVolsi VAAUTHOR: P LoGerfo PAUTHOR: C R Feind CRPUBTYPE: Journal ArticleJOURNALTITLE: Archives of surgery (Chicago, Ill. : 1960) COUNTRY: UNITED STATESTITLE: Coexistent parathyroid adenomas and thyroid carcinoma. Can radiation be blamed?PUBDATE: 19780301
The coexistence of parathyroid adenomas and thyroid cancer in a substantial number of patients with primary hyperparathyroidism has led to speculation implicating ionizing radiation as a possible cause. Experience with a group of 40 individuals harboring both tumors was reviewed and evidence of roentgen ray exposure to the head and neck was found in only one of these patients. Association of parathyroid adenomas and thyroid carcinoma cannot be explained on the basis of prior irradiation to the neck.

9. DOCID:7339 SCORE: 0.00166331389484093DOCNO: 665664OWNER: NLMSTATUS: MEDLINEQUALIFIER: etiologyQUALIFIER: adverse effectsAUTHOR: A B Miller ABAUTHOR: A Kelly AAUTHOR: N W Choi NWAUTHOR: V Matthews VAUTHOR: R W Morgan RWAUTHOR: L Munan LAUTHOR: J D Burch JDAUTHOR: J Feather JAUTHOR: G R Howe GRAUTHOR: M Jain MPUBTYPE: Journal ArticleJOURNALTITLE: American journal of epidemiology. COUNTRY: UNITED STATESTITLE: A study of diet and breast cancer.PUBDATE: 19780601
A case-control study has been conducted in four areas in Canada in which 40 cases of breast cancer matched by age and marital status with neighborhood controls were administered a medical and dietary history questionnaire, a 24-hour recall of dietary information and a four-day diet record. The Study has produced evidence of an association between an increased intake of nutrients, especially total fat, in both pre-menopausal and post-menopausal women with breast cancer. Reasons why a weak association might have been anticipated are discussed, and it is concluded that in reality the association is stronger. Furthermore, its consistency with other evidence, both experimental and international, suggests that it is causal.

11. DOCID:7561 SCORE: 0.00154327418432782DOCNO: 7272905OWNER: NLMSTATUS: MEDLINEQUALIFIER: epidemiologyAUTHOR: D L Levin DLAUTHOR: R R Connelly RRAUTHOR: S S Devesa SSPUBTYPE: Journal ArticleJOURNALTITLE: Cancer. COUNTRY: UNITED STATESTITLE: Demographic characteristics of cancer of the pancreas: mortality, incidence, and survival.PUBDATE: 19810301
Mortality and incidence rates for pancreatic cancer in the United States were examined by various demographic characteristics. Disease rates have continued to increase over time but at a much slower pace than in earlier years. Most recently available rates for blacks were significantly higher than for whites and rates for males of each race were higher than for females. Income and education levels had little influence on incidence rates among either blacks or whites. Incidence rates were not significantly higher in urban as compared with rural areas of Iowa and Colorado. The two-year survival rate for pancreatic cancer was about 5% in recent years and did not vary significantly by race or sex. Smoking and diabetes, the two risk factors most consistently associated with the pancreatic cancer, explain only a small proportion of the disease. Much epidemiologic work remains to be done.

13. DOCID:5493 SCORE: 0.00140618798230577DOCNO: 154458OWNER: NLMSTATUS: MEDLINEQUALIFIER: diagnosisAUTHOR: E Krokowski EPUBTYPE: Journal ArticleJOURNALTITLE: RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin. COUNTRY: GERMANY, WESTTITLE: [Success and apparent success resulting from early cancer diagnosis (author's transl)]PUBDATE: 19790201
Cancer screening techniques are of great value in improving the results of treatment of various tumours. Unfortunately screening and early diagnosis of cancers does not improve the prognosis in every case. Early diagnosis may lead to an apparent success without affecting the final outcome of treatment. Early diagnosis may even be harmful to the patient if the diagnostic and therapeutic methods lead to dissemination of the tumour, as has been shown by a number of authors. Consequently cancer screening and early diagnosis should be confined to those selected tumours which are not affected adversely by diagnostic methods.

14. DOCID:6817 SCORE: 0.00140616833903141DOCNO: 663808OWNER: NLMSTATUS: MEDLINEQUALIFIER: pathologyAUTHOR: K J Syrjänen KJAUTHOR: L H Hjelt LHPUBTYPE: Journal ArticleJOURNALTITLE: Surgery, gynecology & obstetrics. COUNTRY: UNITED STATESTITLE: Tumor-host interrelationships in carcinoma of the female breast.PUBDATE: 19780701
Three hundred and two carcinomas of the female breast were studied histologically with special reference to the morphologic aspects of the tumor, its surrounding host tissue and the regional lymph nodes. The nuclear grade of the tumor was positively correlated with the five year survival rate of the patient. Tumor metastases in the regional lymph nodes were observed to be a sign of a poor prognosis. The stromal lymphocyte and mast cell reactions did not correlate with the frequency of nodal metastases or the five year survival rate. Sinus histiocytosis in the lymph nodes was a sign of favorable five year survival because of its presence in cancer-free nodes only. The paracortical activity of the lymph nodes was an important determinant of whether or not tumor metastases appear in the node.