Paramount's Western animation Rango topped the US box office this weekend in the biggest debut of 2011 so far.

The film, which reunites Johnny Depp with his Pirates Of The Caribbean director Gore Verbinski, took $38 million in its opening weekend, well ahead of Matt Damon's sci-fi thriller The Adjustment Bureau, which entered in second place taking $20.9 million.

Alex Pettyfer's second offering of 2011, the teen fantasy drama Beastly, exceeded expectations by entering third in the top ten with $10.1 million.

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Owen Wilson's comedy Hall Pass falls to fourth with $9 million, while last week's box office topper Gnomeo & Juliet rounds out the top five with $6.9 million.