Cancer
chemotherapy
is the use of drugs to kill cancer cells. Unlike
radiation therapy
and surgery, which are localized treatments, chemotherapy is a systemic treatment, meaning the drugs travel throughout the whole body. This means chemotherapy can reach cancer cells that may have metastasized to other areas.

Chemotherapy is not commonly used for endometrial cancer. The treatment may be ordered for advanced disease, when the cancer has spread to other parts of the body, or if the disease recurs. The drugs are often given in combination and in cycles. All of these drugs are given intravenously at the doctor’s office or in the hospital.

Chemotherapy Drugs Used for Uterine Cancer:

Cisplatin

Cyclophosphamide

Doxorubicin

Carboplatin

Paclitaxel

Ifosfamide

Combination chemotherapy
regimens used in uterine cancer include:

CAP (cyclophosphamide, adriamycin, cisplatin)

Cisplatin and doxorubicin

Cyclophosphamide and doxorubicin

Carboplatin and paclitaxel

Effectiveness

Doctors have yet to find a chemotherapy regimen that is curative or highly effective for advanced or recurrent uterine cancer. In various studies, the response rates to chemotherapy range from 36% to 67%. However, even in those who respond to treatment, the response lasts only 4-8 months on average.

Chemotherapy is sometimes combined with hormonal therapy for the treatment of advanced or recurrent uterine cancer.

Revision Information

This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.