With fans at U.S. Cellular Field and the White Sox dugout watching in disbelief, Cubs pitcher Carlos Zambrano engaged in a shouting match with first baseman Derrek Lee before manager Lou Piniella sent him home. Zambrano then had dinner with Ozzie Guillen, irking Cubs management. In the opening series, Piniella attacked Sox analyst Steve Stone's resume after Stone criticized him for not playing Tyler Colvin. In a Sunday night game at Wrigley, Gavin Floyd and Ted Lilly took a double no-hit bid into the seventh.

2. 2006: White Sox win 4-2

Cubs catcher Michael Barrett punched A.J. Pierzynski after a collision at home at the Cell, igniting the first and only City Series brawl. Barrett and Pierzynski shook hands before the opener at Wrigley. In Game 2 at Wrigley, Pierzynski cranked a two-out, three-run homer off Ryan Dempster in the ninth to give the Sox an 8-6 victory, stunning the crowd that had booed Pierzynski during every at-bat. Fans littered the field, causing a long delay. Upset with being asked if he felt like "here we go again," Dempster replied, "It's pathetic, it really is."

3. 2007: Cubs win 5-1

In Piniella's first season as Cubs manager, Ryan Theriot's squeeze bunt off closer Bobby Jenks scored pinch runner Angel Pagan in the ninth inning of Game 2 at the Cell, leading the Cubs to a 2-1 victory. "Couple of weeks ago, Lou was the worst manager in baseball," Guillen said. "And all of a sudden he beat the White Sox on a squeeze play in the ninth. Wow, he's a genius the last two days."

4. 1997: White Sox win 2-1

"We have the drunkest fans in baseball," Cubs outfielder Brian McRae bragged to Sox first baseman Frank Thomas. Thomas replied, "We have the working-class fans here." McRae countered: "Our fans are working. They're working business deals on cellphones during the games." And thus it began at Comiskey Park. Wilson Alvarez threw a shutout in the finale to give the Sox the first-ever interleague series. "Hats off to him," Cubs first baseman Mark Grace said. "But I'll bet you he's going to say, 'God, I wish I could play them every day.'"

5. 2001: White Sox win 4-2

In the second series at Wrigley Field, Jose Valentin mocked Cubs slugger Sammy Sosa by kissing his fingers and tapping his heart in the Sox dugout after hitting a homer in a victory. "I'm not going to apologize because I don't think I did anything to offend anyone," Valentin said. "Sammy has no problem with it, so I won't say I'm sorry." Valentin became a cult hero to Sox fans.

6. 2009: White Sox win 4-2

In Game 1 at the Cell, Piniella called outfielder Milton Bradley a "piece of (bleep)" after Bradley's dugout explosion and sent him home. The two made up the next day. "Like I've said, I don't have the same set of rules as other people," Bradley said. "I've committed mistakes in my past to where you don't get the leeway other guys might get. To a certain extent, I guess that's fair."

7. 2011: White Sox win 4-2

One year after his dugout tirade, Zambrano gave up three first-inning runs before settling down for a 6-3 victory. "Thank God I made it through the first day at U.S. Cellular Field," Zambrano said. In the second game, Guillen booted Geovany Soto's face mask after an argument at home plate, eliciting laughs from both dugouts.

8. 2012: White Sox win 4-2

In the final moment of his 14-year career, Cubs reliever Kerry Wood struck out Dayan Viciedo at Wrigley Field in the opener of the series. Wood walked off the field to a standing ovation, carrying his son, Justin, who ran out of the dugout. "It was time to give somebody else a chance," Wood said. It was also the game Cubs right-hander Jeff Samardzija accidentally hit Paul Konerko in the face with a split-fingered fastball. Samardzija apologized, and Konerko agreed it was an accident.

9. 1998: Cubs win 3-0

The Cubs swept the Sox at Wrigley to run their winning streak to nine, while Sox stars Robin Ventura, Frank Thomas and Albert Belle fumed because their shoes had been stolen from the visitors clubhouse. The Cubs stole the first game when the ivy ate up Magglio Ordonez's double, preventing a run from scoring because of the ivy rule. The "Ivy Game" became a classic. "It'll go down in folklore," Ventura said afterward. "But do you think they're going to tear down the vines because of that?" They did not.

10. 2002: Series tied 3-3

The Sox may have sealed the fate of Cubs manager Don Baylor, who was fired days after the second series ended. At Comiskey, Wood hit Konerko in the helmet with an offspeed pitch, but Konerko bounced back and hit two homers to lead the Sox from an eight-run deficit to a stunning 13-9 victory. "He's the type of guy that this type of stage he thrives on," Sox manager Jerry Manuel said. It was the biggest blown lead for the Cubs since 1976, when Mike Schmidt hit four home runs to help the Phillies escape a 12-1 deficit.

11. 2005: Series tied 3-3

Sox GM Ken Williams and Cubs minor-league baserunning instructor Vince Coleman, a longtime friend, engaged in a heated exchange during Cubs batting practice at Wrigley. Coleman was upset Williams denied the Cubs' request to let Coleman sit in the dugout. Umpires' warnings were delivered two straight days at Wrigley, once after Zambrano hit Aaron Rowand and nicked Pierzynski. Cubs bullpen coach Juan Lopez told Guillen rats were known to hide in the outfield vines, starting a long-running telling of rat stories.

12. 2016: Series tied 2-2

In a made-for-psychotherapy matchup between emotional starters, John Lackey outdueled Chris Sale in the finale to help the Cubs to a split. But new Cubs closer Aroldis Chapman, who arrived on the first day of the series with a testy press conference, ultimately stole the show by wowing the crowd at Wrigley with 103-mph fastballs.

13. 1999: White Sox win 4-2

The veteran Cubs were playing well until the rebuilding Sox swept them in June at Wrigley, sending them on a plunge from which they never recovered. "I guess it's a good thing for the bars because you can debate it all day," Cubs pitcher Kevin Tapani said. Mike Caruso's two-run eighth-inning homer won the finale after a 31/2-hour rain delay. Police were called when angry fans who had exited during the deluge demanded to be allowed back inside.

14. 2003: White Sox win 4-2

Shortly after his corked-bat episode, Sosa had to wear earplugs during batting practice, prompting Sox catcher Sandy Alomar Jr. to quip, "I wasn't sure if it was an earplug or cork coming out of his head." Third-base coach Wendell Kim cost the Cubs a game with a decision that had fans calling for his head. Then Kim made the same call the next day that worked. Kim said he was so happy he was crying in the shower.

15. 2008: Series tied 3-3

In the second round of the series, White Sox fans waved a giant blue "L" flag in the left-field bleachers at Wrigley during the ninth inning of a Sox victory. Before Game 2, Guillen told Cubs executive Crane Kenney a story of all the rats he had seen, to which Kenney cracked, "Ozzie, the rats are part of the Wrigley Field ambience." The Cubs then hit four home runs in the fourth inning, including two by newcomer Jim Edmonds, tying a club mark set in 1930 and matched in 2000.

16. 2000: Series tied 3-3

The Sox won the opener at Comiskey in 14 innings, and clinging to a one-run lead with two out and the tying run on third in the eighth inning of Game 2, reliever Sean Lowe picked Grace off first with Sosa at the plate. It was the Sox's ninth victory in 10 games en route to a division title.

17. 2004: Cubs win 4-2

After losing two of three on the South Side, the Cubs swept in Wrigley, taking the finale on Damaso Marte's bases-loaded walk to Todd Walker in the ninth. "It's not the way you draw it up," Walker said. "Those are the types of at-bats that give people heart attacks."

18. 2015: Series tied 3-3

Chris Coghlan hit two home runs to lead the Cubs to a 6-5 victory over former Cub Samardzija in the City Series finale at the Cell, their 14th victory in 15 games. In Game 2, a fan threw a plastic bottle of beer at Cubs rookie left fielder Kyle Schwarber. "I guess that's what this series is all about," Schwarber said, joking he should have shotgunned it.

19. 2013: Cubs win 4-0

Samardzija threw a two-hit shutout — the first of his career — in the rebuilding Cubs' 7-0 romp in the opener of the City Series at the Cell. "Really, the fans make this series," he said. "Let's be honest. The excitement and passion they have for both teams, you hear it and feel it in the dugout." The Cubs outscored the Sox 32-8 in the four-game sweep of the series.

20. 2014: White Sox win 3-1

The Cubs honored the retiring Konerko before his final game at Wrigley. "As many times as I've been hit here, it might be a first-aid kit or some stitches," Konerko said. The Sox clinched the Crosstown Cup at the Cell with an 8-3 victory before a crowd of 21,075, the smallest in City Series history.