Manual of clinical problems in adult ambulatory care

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Because estrogen given in this fashion enters directly into the systemic
circulation, there is no first-pass effect; thus, the increased synthesis of hepatic
proteins ... The patch is effective for treating symptoms of the menopause as well
as for maintaining bone mass. ... after 3-5 days), many experts are now
recommending continuous estrogen treatment with a progestin given on days 1
to 12 of each month.

Title

:

Manual of clinical problems in adult ambulatory care

Author

:

Laurie Dornbrand, Axalla J. Hoole

Publisher

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Little Brown and Company - 1992-04-01

ISBN-13

:

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