Abstract : In experiments in rabbits and primates we have: (1) Reaffirmed a prolonged reduction in blood volume and visceral organ flow for periods of at least 18 hours after resuscitation from hemorrhagic shock. (2) Shown that none of the readily identifiable humoral controls of blood pressure or vascular resistance are involved in this flow redistribution (i.e., renin/angiotensin, cathecholamines, thromboxane). (3) Demonstrate improved survival in shocked rabbits treated with ATP-MgC12. (4) Failed to demonstrate any change in mortality in shocked animals subjected to endorphin antagonism with naloxone. (5) Shown no favorable effect of resuscitation with fluorocarbons on survival in rabbits in hemorrhagic shock.