This thesis is divided into four chapters. Chapter one is a review of dearomatising [3,3]-sigmatropic rearrangements and is split by sub-classification of Claisen rearrangements. Chapter two introduces the decarboxylative Claisen rearrangement (dCr) and details investigations of the application of this reaction to compounds containing furan rings. Chapter three focuses on the natural product hinckdentine A. It begins with a brief review of previous studies towards the natural product, before discussing attempts to synthesise this compound by a decarboxylative Claisen rearrangement. Chapter four provides experimental procedures and characterisation data.