Euro Brain Injury 2017

On behalf of the Conference Organizing Committee, it is with great pleasure that we welcome you to the official website of the 3rd International Conference on Neurological Disorders and Brain Injuryduring April 18-19, 2017 at London, UK

Brain Injury defined as an alteration in brain function or other evidence of brain pathology. Brain Injury occurs as a result of severe injuries, disease, or health conditions like Acquired Brain Injury is an injury to the brain that has occurred after birth and Traumatic Brain Injury (TBI) caused by an external force. There are 7.7 million people in the Europe who have experienced Brain Injury and have disabilities which has a significant impact on their lives. Mainly Brain stroke, epilepsy, dementia, headache and TBI are the neurological conditions suffered in Europe.

The brain is the most complex part of the human body. The three Brain chemicals noradrenaline, dopamine and serotonin are involved in both bodily functions and Brain. The structural connectivity describes anatomical connections linking a set of neural elements whereas functional connectivity is generally derived from time series observations, and describes patterns of statistical dependence among neural elements. Brain connectivity is thus crucial to elucidating how neurons and neural networks process information. The goal of this session is to understand the Causes, Origin, Genesis and Source of various types of Neurological disorder of brain.

Neurodegenerative disease is defined as a range of conditions which primarily affect the neurons in brain. Neurodegenerative diseases are debilitating and untreatable conditions that result in death of nerve cells or progressive degeneration. Aging and genetic factors are the overwhelming causes of several neurodegenerative disorders. The commonness of these disorders is snowballing due to the increase in the human life span, making neuronal degenerative pathologies a serious public health problem. This causes problems with mental functioning and movement. The goal of this session is to understand the Causes, Origin and Source of various types of Neurodegenerative diseases of brain like Dementias and Huntington’s Disease etc.

Cerebrospinal fluid bathes the spinal cord and brain and functions as a cushion to defend these areas. Cerebrospinal fluid leaks happen through a communication between the nose and lining of the brain. These communications may happen immediately or result from prior sinonasal surgery or trauma. Complications may happen if the cause is trauma or surgery. Infections after trauma or surgery can lead to meningitis and serious complications, such as swelling of the brain. Most Cerebrospinal fluid leaks are a complication of a spinal tap or surgery.

Pathophysiology of Brain disorders was affected by various factors such as cellular mechanism and Molecular , Altered cerebral hemodynamic, Cerebral oxygenation, Cerebrovascular autoregulation, Excitotoxic cell damage, Cerebral metabolic dysfunction, Inflammation and Changes in coordination or balance. There are more than 1.2 million people in the Europe living with a neurological condition which has a vital impact on their lives.

Brain Disorders are the extremely common cause of serious disability and have a major but often unrecognized, impact on health and social services. When the brain is damaged, it can affect several different things, including your sensation, your memory, and even your personality. Brain disorders include any disabilities or conditions that affect the brain. This includes those conditions that are caused by Brain injury, genetics, neurological disorders, or traumatic injury. There are 10 million people in the Europe who have experienced neurological condition which has a great impact on their lives. Mainly stroke, epilepsy, dementia, headache and brain injury are the neurological conditions suffered in Europe

A stroke happens when the blood supply to the brain is disrupted due to clot. The way a stroke affects the brain depends on which part of the brain suffers damage, and to what degree. Sitting just above the spinal cord, the brain stem controls your heartbeat, breathing and blood pressure. It also controls your hearing, swallowing, speech and eye movements. The goal of this session is to understand the Causes, Origin, and Source of various types of the stroke of the brain like ischemic stroke, which is caused by a blood clot etc.

Brain surgery is a critical and complicated process that involves repairing structural problems in the brain. The type of brain surgery done depends highly on the condition being treated. For example, a brain aneurysm is typically repaired using an endoscope etc

Brain injury has become the leading cause of mortality and morbidity all over the world. Every year 1,365,000 emergency department visits due to brain injury. Earlier to arrival to the ICU, patients with severe Brain Injury are normally received, stabilized and resuscitated in the operating room or emergency department. Severely brain-injured patient has been transferred to ICU, the management consists of the terms of high-quality general care and various strategies aimed at maintaining hemostasis with: Prevention of intracranial hypertension, Stabilization of the patient, Maintenance of an adequate and stable (CPP) cerebral perfusion pressure, Avoidance of systemic, secondary brain insults (SBI), Optimization of cerebral hemodynamic and oxygenation.

With mild or critical brain injury, diagnosis is usually self-evident. In the appearance of other life-threatening injuries, which is often the closed brain injury can be missed, a case with motor vehicle accidents. The focus is on lifesaving measures. The patient may be on a ventilator and serious and the evaluation for brain injury will be limited until the patient is allowed to emerge from mechanical ventilation and medications. Injury to particular areas of the brain will cause specific symptoms. For example, Injury to the cerebellum will cause loss of coordination and balance, frontal lobes injury will cause loss of higher cognitive functions, such as loss of inhibitions leading to inappropriate social behavior. The brainstem controls things like breathing and heart rate, as well as arousal. An injury to this area could inhibit any of these processes.

Biomarkers present a powerful approach to studying the spectrum of neurological disease with applications in randomized clinical trials, screening, observational and analytic epidemiology, diagnosis and prognosis. Biomarkers of axonal, astroglial and neuronal damage could be practiced to diagnose brain injury. Such biomarkers could give important information for medical counseling of at-risk individuals, such as concussed athletes and military personnel. Cerebrospinal fluid markers (CFM) are preferred over peripheral blood markers, owing to their increased proximity to the brain and decreased susceptibility to the confounding impacts of various extracerebral factors

For essentially every known human disease, researchers attempt to induce alike aspects of the disease in animals to build an animal model. Animals are used as models of Brain injuries, Parkinson’s, Alzheimer’s spinal cord injuries, congenital blindness etc. Researchers generally use rabbits in toxicity and safety testing of medical devices, drugs and vaccines. In 2009, more than 244,000 rabbits were used in research, more than any other species covered under the Animal Welfare Act, followed next by hamsters and guinea pigs that are both used a great deal in toxicity testing and as models for cardiovascular, neurological diseases, infectious and drug abuse research.

Brain injury is a clinical diagnosis that can have significant effects on an individual's life, yet is difficult to identify through traditional imaging techniques. Researchers are examining many cases related to brain injuries. Scientists are designing new evaluation tools to assess the problems that people who have suffered brain injuries encounter. Scientists are also examining the effects of various treatment methods that have been developed

According to the latest survey conducted by WHO, it is revealed that Neurological Disorders encompassing Stroke, Alzheimer & Dementia, Epilepsy and many more accounts for more than 12% of deaths worldwide on an average and it is also predicted that the number of disability –adjusted life years vanished due to Neurological disorders are expected to accelerate from 95 million globally in 2015 to 103 million by 2030.Moreover, the worldwide cost of neurological sequelae solitary estimated in 2010 was US$ 2.5 trillion and it is assumed that the value will spike to over US$ 6 trillion by 2030.

Alzheimer's Research UK currently funds 150 research projects across the UK and has committed nearly £40million to dementia research. Their research will focus on improving the quality of life of those already living with Alzheimer’s disease and other forms of dementia.

The Alzheimer's Association funds independent investigators worldwide, they have awarded over $335 million to more than 2,250 projects. Research conducted by the Alzheimer's Society, shows that there will be 850,000 people living with dementia in the UK by 2015. This will cost the UK £26 billion a year.

Two-thirds (£17.4 billion) of the cost of dementia is paid by people with dementia and their families, either in unpaid care (£11.6 billion) or in paying for private social care. This is in contrast to other conditions, such as heart disease and cancer, where the NHS provides care that is free at the point of use.
National Alliance provided fund of $650 million to fuel the research on mental illness. NARSAD Young Investigator Grant provides $30,000 per year on research in Neural and behavior disorders such as schizophrenia, mood disorders, anxiety disorders, or child and adolescent mental illnesses. Brain tumour research receives less than 1% (0.7%) of national cancer research spending in the UK.

The number of people living in the UK with neurological conditions are reported by the specialist organisations as follows:

Parkinson’s disease - 120,000
Multiple sclerosis - 100,000

Huntington’s disease - 6,500-8,000

Motor neurone disease - 5,000

Progressive supranuclear palsy - 4,000-10,000

Multiple system atrophy - 3,000

Why London?

London is the most populous city in the United Kingdom. There are about 15 Universities in and around London which are working in the field of Neurological disorder. Around 1000 neurologist, psychiatrist and neurosurgeons are working exclusively on Neurological disorder in London. Along with professional services, media companies are concentrated in London and the media distribu­tion industry is London’s second most competitive sector.

Why to attend???

3rd International Conference on Neurological Disorders and Brain Injury is a unique forum to bring together worldwide distinguished academics in the field of neuroscience and neurology, Brain researchers, public health professionals, scientists, academic scientists, industry researchers, scholars to exchange about state of the art research and technologies.

Aim of this conference is stimulate new ideas for treatment that will be beneficial across the spectrum of Brain disorders.

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