Interpretive Summary: Greens are an excellent source of minerals, vitamins, and other dietary constituents. Lithium salts have potential for pest control in organic agriculture. In this greenhouse study, we observed that when lithium sulfate is added to the soil at low levels (10 lbs /Ac), leaves of the spinach cultivar ‘Samish’ increased in vitamin C content by 17% and leaf total sulfur (inorganic and organic) concentrations in a mustard greens cultivar, Florida Broadleaf, increased by 60%. Plant fresh weights and leaf dry weights grown in one of the two soils used, were also increased by lithium applications to the soil. Soil type and light intensity were both found to influence mineral nutrient, plant pigment, and oxalate concentrations in spinach and mustard greens. Lithium, though not required by plants, is known to enhance general wellness in people.