The Loop 1604 eastbound main lanes will be closed this weekend between Blanco Road and U.S. 281, starting at 10 p.m. Friday. They will reopen 5 a.m. Monday or once the work is completed.

Construction crews will be removing and laying asphalt on the main lanes.

Traffic will have to exit Blanco Road and enter the highway again at the Stone Oak Parkway entrance ramp.

In addition, the exit ramp to Stone Oak Parkway from westbound Loop 1604 will be closed from 9 a.m. to 4 p.m. Friday, and from 7 a.m. to 4 p.m. Saturday. The exit ramp to Donella off of U.S. 281 southbound also will be closed, from 7 a.m. to 4 p.m. Saturday.