Interim Management Statement

Oxford, UK - 19 November 2013: Oxford BioMedica ("Oxford BioMedica" or "the Company") (LSE: OXB), the leading gene-based biopharmaceutical company, today publishes its interim management statement for the period from 1 July to 18 November 2013.

· Winner of UK Technology Strategy Board (TSB) funding award in August; £1.8 million grant for EncorStat®confirmed by the TSB in October following successful due diligence

· Agreement from the US Food and Drug Administration (FDA) and the French regulatory agency, ANSM, to resume recruitment into the RetinoStat® Phase I, StarGen™ Phase I/IIa and UshStat® Phase I/IIa studies following a voluntary pause in recruitment

ProSavin®

· Evaluation of a more potent formulation of ProSavin® (called OXB-102) is ongoing

At 31 October 2013, the Company had a net cash1 balance of £3.6 million. In order to give the Company further flexibility, Oxford BioMedica has entered into a conditional £5.0 million loan facility agreement with its largest shareholder, Vulpes Life Sciences Fund - see separate announcement issued today.

1. Cash, cash equivalents and available for sale investments

OUTLOOK

During the rest of 2013 and 2014, revenues are expected to be generated from intellectual property, development and manufacturing alliances and a potential significant option fee that may arise should Sanofi choose to exercise its option over RetinoStat®. Oxford BioMedica remains focused on completing the RetinoStat® Phase I study as soon as possible, generating further recurring income and developing the next generation of highly valuable LentiVector® platform product opportunities.

John Dawson, Chief Executive Officer of Oxford BioMedica, said:"The past few months have been positive on a number of fronts and operationally the Company continues to build a very strong position. The conditional £7.1 million AMSCI award gives us the confidence to develop a UK centre of excellence and to become a partner-of-choice for companies needing gene- and cell-therapy manufacturing solutions; the LentiVector® platform product portfolio continues to generate positive data; and, following extensive characterisation studies using our internal state-of-the-art analytical methods, we received support from the US and French regulatory agencies to resume recruitment into our ocular trials. With multiple opportunities ahead, the Directors remain focused on bringing further revenue into the business and creating growth at Oxford BioMedica."

-Ends-

For further information, please contact:

Oxford BioMedica plc:

Lara Mott, Head of Investor Relations and Corporate Communications

Tel: +44 (0)1865 783 000

Media Enquiries:

Mary-Jane Elliott/Emma Thompson/Matthew Neal

Consilium Strategic Communications

Tel: +44 (0)20 7920 2354

Notes to editors

1. About Oxford BioMedica®

Oxford BioMedica plc (LSE: OXB) is a biopharmaceutical company developing innovative gene-based medicines and therapeutic vaccines that aim to improve the lives of patients with high unmet medical needs. The Company's technology platform includes a highly efficient LentiVector® gene delivery system, which has specific advantages for targeting diseases of the central nervous system and the eye; and a unique tumour antigen (5T4), which is an ideal target for anti-cancer therapy. Through in-house and collaborative research, Oxford BioMedica has a broad pipeline with current partners and licensees including Sanofi, Pfizer, Novartis, GlaxoSmithKline, MolMed, Sigma-Aldrich, Biogen Idec, Emergent BioSolutions, ImaginAb and Immune Design Corp. Further information is available at www.oxfordbiomedica.co.uk and www.oxbsolutions.co.uk.