I have used a lot of caulk for many different projects. The only one I have had any real success with is window caulk, like Quad. You could not use this for interior projects like bathrooms but it is the only caulk I have used that does not mold, discolor or peel over time.

Even the best caulk will mildew in a bathroom sooner or later if the air is dark warm and moist. The absolut BEST preventative of mildew in the bathroom is adequate ventilation. I use a minimum 100 CFM, maximum 1.0 sone fan. If the room is larger than about 10 X 10, consider higher CFM, possilby a remote inline fan.

Ian's comment about Quad is spot on in my experience. Not sure what the stuff if formulated from but it's amazingly resilient and when removed a couple of years later, still seems almost "tacky". That said, it's not for interior use due, I believe, to the VOC issue. Then again... I've used it on a number of occasions "inside" and once the VOC's liberated, things were fine. Anything with polyurethane I'd stay away from. Silkolene, various others and even the 3M $20 a tube I tried from the boat store (uh huh- those were supposed to be the cat's-ass of caulk- made in France of all things!) All yellowed terribly once the usual cleaning agents used in bathrooms were applied. Terrible stuff, just don't understand what the story is with Poly....

In accordance with EPA, when the spot infected with mildew is bigger then 30 sq . ft ., you need to seek for specialist to do a mold elimination for you. The simple truth is, at times mould is concealed behind the wall surfaces, under the carpeting, and so forth. Its often a good approach to have a mould inspection if you happen to suspect big mould contamination. In the event you in Nj, check out this company - Mold Removal NJ . Best of luck!

I've heard that polyseamseal is a good product for inhibiting the growth of mold and mildew on your caulk. Wanted to get some opinions on this.

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A poorly built shower will take on a lot of water and often Mastic is used to set tiles in our wet rooms. By building a better shower you help eliminate food sources for mould and reduce the water absorption rates.