Updates don't install | Update failure or U44M errors

Issue

When you try to install an update to Adobe Photoshop CS6, you receive one of the following errors:

Update Failure

U44M1P7

U44M2P7

U44M1P6

U44M1|210

Solution

Many update errors are caused by missing or modified files that Photoshop requires, typically removed by a disk cleanup utility (such as CleanMyMac or MacKeeper). Make sure that you have the latest updates for your cleanup utilities or discontinue use.