Apo-Metronidazole
Synthesis Reference

Apo-Metronidazole
Molecular Weight

Apo-Metronidazole
Melting Point

Apo-Metronidazole
H2O Solubility

Apo-Metronidazole
State

Solid

Apo-Metronidazole
LogP

-0.262

Apo-Metronidazole
Dosage Forms

Tablet; Intravenous injection

Apo-Metronidazole
Indication

Treatment of acute acne rosacea

Apo-Metronidazole
Pharmacology

Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.

Apo-Metronidazole
Absorption

Well absorbed

Apo-Metronidazole
side effects and Toxicity

Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)