Cushings Syndrome (CS) is a hormonal disorder caused by high levels of the hormone cortisol. The most common cause of Cushings Syndrome is excess steroid medications. Otherwise, Cushings Syndrome is caused by growths (tumors) in the body.

What are the Signs and Symptoms?

Change in fat distribution, with more fat in the upper body, such as a rounded face, increased fat around the neck, a large abdomen, and thinning arms and legs

The skin becomes fragile and thin, with easy bruising and poor healing. Purplish pink stretch marks called striae may appear

Women may have excessive hair growth

Bones are weakened due to osteoporosis, resulting in risk of fracture

Changes in mood, including fatigue, irritability, anxiety and depression

Hypertension and diabetes

Changes in the menstrual cycle in women. Men may describe diminished sexual libido and performance.

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