Reproducible

End point determination

Temperature difference can be used together with optional product temperature sensors to determine the end point.

Sample protective state

If the sample temperature rises above the set collapse temperature or the pressure is outside the safety range then the sample pretective state is activated. This reduces the pressure and stops the shelf heating.

Flexible drying chambers

Adjustable shelf distance according to your application needs

Possibility to link two manifold racks together

Second Interface

An additional Interface can be connected and placed outside the fume hood to control the process outside

Upgrade to Interface Pro anytime to enable working within the advanced Lyovapor™ Software

Ergonomic handling

Easy reading of process parameters due to the adjustable display

Adaptable position of the display at the front or on the side

Comprehensive service

Voice of the customer

“The Lyovapor™ L-200 is an extremely high quality laboratory Freeze Drying system for a wide range of applications. The operation of the Freeze Dryer and the drying of all kinds of different samples are straightforward."

Which materials can be freeze dried?

In general, all materials can be freeze dried, except for samples of oil rich products, sugar rich materials, products forming an impervious skin, and products containing high salt concentration.The material can be in a liquid state as an emulsion, dispersion or as a solid of bulk materials.

How should the process parameters be chosen in order to optimize the primary drying phase?

The pressure must be below the ice vapor pressure of the frozen samples. However, very low pressures are often counterproductive since the vacuum is not the only factor facilitating the sublimation process. Since sublimation is an endothermic process, it is also important to supply the frozen samples with energy with respect to the critical sample temperatures.

What are the advantages of using heatable shelf?

The heated shelf provides the energy to increase the sublimation rate and as a result the drying time becomes shorter. Furthermore, the process is reproducible due to the consistent input of energy. Furthermore, the shelf can be heated up to 60°C which can dramatically decrease the moisture content to about 1%.The Lyovapor Pro system with heatable shelves gives accurate heat distribution to within +/-1 °C across the entire shelf, thus improving the efficiency of the process.

Which critical sample temperatures should I pay attention to during the primary and secondary phase?

In the primary phase the glass transition temperature (Tg`), the superior collapse temperature or the eutectic temperature of the frozen sample are the key parameters. In the secondary drying the glass transition temperature as well as the eutectic temperature of the solid sample should not be exceeded. The Lyovapor Pro system offers the sample protection mode preventing sample damages in consequence of the temperature rise above the critical values.

Which sensors are available for end point determination and process monitoring?

Why should I chose Infinite Control for my Lyovapor instrument?

Infinite Control is the synergy of the Pro interface with access to heatable shelves, the Lyovapor software for data logging, process control, and the Monitor App for real-time process monitoring. This combination enables a convenient, efficient freeze drying cycle and optimum products.