3.1.1 Regulatory Hormones

GOAL: To describe the function components of the reproductive systems of male and females, the physiological basis for reproductive cyclicity in females and changes in the reproductive systems that occur at the puberty in males and females.
3.1 Objective:
To describe the hormones of the hypothalamic-pituitary-gonadal axis that control reproductive function in females and males.
3.1.1 Regulatory Hormones ( Interactive Diagram)
-What pituitary hormones simulate the gonards in males and females?
-What cells synthesize and secrete gonadotropins
-Why is gonadotropin secretion cyclical in females and not in the males?
-What are FSH and LH and what is the plasma half-life of FSH and LH?
-Why do peripheral plasma levels of FSH and LH not reflect pulsating GnRH secretion?
-What organs are important for removal of FSH and LH from the circulation?
-What cells in the ovaries and testis are simulated by FSH and LH?
-What type of receptors mediates the cellular actions of FSH and LH?
-What is GnRH, where is it synthesized, and where and how is it secreted?
-What are the target cells for GnRH?
-What are the physiological roles of sex steroids?
-What is the effect of the neonatal exposure to the male levels of testosterone on the gonadotropin secretion in the adulthood?
-What is the effect of castration of neonatal male rats on gonadotropin secretion?
-What are inhibin and activin and where are they synthesized in the males / females?
-What controls the synthesis of the inhibin and activin in males and females?
-How does the synthesis and secretion of inhibin vary in females?
-What are the actions of inhibin and activin in gonads and in the hypothalamic-pituitary unit?
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