Methotrexate

Methotrexate is an experimental antimetabolic chemosterilant that shows promise in control of insects through sterilization. This ubiquitous chemical also has medicinial value in humans as both an anti-cancer agent and has been used to treat arthritis. The drug acts by inhibition of dihydrofolic acid reductase, resulting in an inhibition of the synthesis of purine nucleotides and thymidylate.