Methods

We analyzed 232 CM patients diagnosed from 1989 to 2013 at a University Hospital. Genomic DNA of patients was analyzed by polymerase chain reaction, and enzymatic digestion, for discrimination of pertinent genotypes. RFS and OS were calculated using the univariate Kaplan-Meier estimate probabilities, and differences between survival curves were analyzed by the log-rank test. OS was calculated from the date of diagnosis until the date of death or last follow-up.