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Constrain to acidosls back and forward steps. Treatment of the lactic acidosis induced by metformin is based on the use of supportive general measures; in severe cases, procedures of extrarrenal purification like hemodialysis or continuous hemodiafiltration have been successfully used.

Metformin is an antihyperglycemic agent commonly used in diabetic patients. Metabolic effects of metformin on glucose and lactate metabolism in noninsulin-dependent diabetes mellitus. We use cookies to help provide and enhance our service and tailor content and ads.

Biochem J ; Pt 3: Diabetes Care ;33 Suppl 1: Lactic acidosis is an uncommon side effect of metformin use, which is more likely to arise in patients with certain predisposing factors. J Clin Endocrinol Metab ;81 Check out this article to learn more or contact your system administrator.

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Lactic acidosis is a serious complication of metformin therapy and is more frequent in patients with kidney failure and other intercurrent complaints.