Cystistat® has a wide range of published papers supporting the treatment of cystitis.

Cystistat® efficacy has been described in:

Bladder Pain Syndrome / Interstitial Cystitis (BPS/IC) 1

Recurrent Bacterial Cystitis (RBC) by the protection of the urothelium 11, 12

Radiation-induced cystitis (RIC) 5, 13, 14

How does Cystistat® work?

The site of action of Cystistat® is the urothelium.

Cystistat® has been developed to temporarily replenish the deficient GAG layer on the bladder epithelium. It has a double effect:

Cystistat® has a barrier effect (primary) 15

Extracted from Moreland publication which is based on the osteoarthritis model 16

Cystistat® also has a regenerative role (secondary effect) 17

In the urothelium, HA is predominantly found at the basal cell membrane 17

Cystistat® restores a good environment for cell proliferation 17

Cystistat® has a regenerative role of the GAG layer in the bladder and can provide a chance to cure*1,18

* However, late recurrences surpassing the observation period cannot be excluded. 50 % of the patients were free of bladder symptom after primary therapy of Cystistat® without any further therapy during the 5 year follow-up 1

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*However, late recurrences surpassing the observation period cannot be excluded. 50 % of the patients were free of bladder symptom after primary therapy of Cystistat® without any further therapy during the 5 year follow-up1