Methods: A total of 39 patients, 19 with low-grade gliomas and 20 with high-grade gliomas, and 15 deceased controls who underwent autopsy after trauma were included. Adhesion molecules were measured using enzyme-linked immunosorbent assay and the results were analyzed.

Results: Statistically significant differences were found between the patients and controls regarding every molecule (p<0.05). Furthermore, significantly higher levels were found in patients with high-grade gliomas compared with those with low-grade gliomas.

Conclusion: These results suggest that adhesion molecules may have a role in glioma formation and targeted therapies could help in the treatment of these devastating brain tumors.