WORCESTER — A Leominster man was killed and two people were seriously injured Friday when a car traveling south on Interstate rolled onto its roof on a guardrail, hanging precariously 25 feet above the intersection of West Boylston Drive and Mattson Avenue.

State police Friday night said Brian Pedone, 28, of Leominster, was pronounced dead earlier in the day at UMass Memorial Medical Center — University Campus.

Two ladder trucks, one on Mattson Avenue and one on Exit 1 of I-, were needed to help stabilize the vehicle and remove victims of the accident, which occurred about 10:30 a.m. near the Greendale Mall.

State police said the three victims had to be extricated from the car. They were all taken to UMass Memorial's University Campus. The two other victims, identified only as a 31-year-old Grafton man and a 45-year-old Worcester man, were listed in critical condition Friday night, state police said.

The right lane of I- and Exit 1 were closed while police investigated.

About a quarter of the car hung over the edge of the wall. The vehicle's bumper was torn off in the accident, and it and other debris fell onto Mattson Avenue.

Worcester Fire Department Deputy Chief Geoffrey Gardell said firefighters from Grove Street and Greendale fire stations responded, and that firefighters with the department's heavy rescue team performed the extrication. District Chief Michael Conley oversaw the operation, Chief Gardell said.

State police said the cause of the accident remains under investigation.