A policeman is flagged down by a 32-year-old woman at a park in Joliet, Illinois who says she can't remember who she is or how she got there. She is later found to be a mother of four children living in Jackson, Michigan. Her name is Amber. She has not recovered memory of her earlier life or what triggered her amnesia. Doctors are at a loss to know what caused this case of "global amnesia."

Jim, a rock sculptor living near Ontario, California, looks like Indiana Jones in the movie Raiders Of The Lost Ark. Prop him up on a bar stool drinking down some brew and he would fit into any beer commercial. He is manly but has an unmanly and embarrassing problem. All of a sudden he can't seem to control his bowels. He is running to the bathroom all the time. His doctor says it is irritable bowel syndrome, a now common condition that forces sufferers to be closely tethered to bathrooms. A drug is prescribed that slows down gastric transit time but induces sleepiness, and can't be taken while driving. But what is the cause of his problem?

Robert, an award-winning journalist, wakes up one morning with a slight weakness in his left leg. Then he begins to lose his ability to speak. He has to say "yes" or "no" by shifting his eyes. Doctors offer an experimental drug. For unexplained reasons, doctors delay treatment until Robert loses feeling throughout his body and is now permanently confined to a wheelchair. Doctors say Robert had a bout of Guillain Barré syndrome that never went into remission as most other cases do. Again, doctors have no idea of the cause of this progressive loss of nervous system control, some believing it is triggered by a virus.

Steve, age 35, had been suffering heart palpitations for years and finally was diagnosed with atrial fibrillation, a quivering heart muscle in the top chambers of the heart. Surgery and medication began to slowly help Steve regain his energy. Steve wonders if his children will inherit his problem. Despite successful treatment, neither surgery nor medication addresses the still unknown cause of atrial fibrillation. Millions of Americans, mostly men, face this same problem. Treatment consists of prescribing blood thinners to prevent a blood clot in the heart being thrown into the lungs or brain and controlled destruction of the heart muscle (ablation) itself. But what is its cause?

Martin, at age 56, first noticed could not keep up with his 70-year old brother in law when out hunting. He began to experience shortness of breath, fatigue, swelling in his ankles and a persistent cough. The diagnosis: heart failure. The cure: the implantation of a device in his chest that helps his heart pump blood. The device is credited with saving his life. More commonly heart failure is treated with a battery of drugs. But a recent study shows the drugs are of negligible value.

Strikingly, all of these illnesses may be related to a single nutritional deficiency.

Vitamin deficiencies not on modern medicine's radar screen

Could modern medicine completely miss detection of a widespread vitamin deficiency disease that emanates as many different diseases? Dr. Derrick Lonsdale MD, a practicing physician in Cleveland, Ohio and noted expert on the subject, says "it is possible to start thinking that our disease model is catastrophically wrong." 22116701

In a recently published journal article Dr. Lonsdale says that the origin of this oversight can be traced to when "vitamins fell into disrepute and even today they are often spurned by physicians who regard their pharmaceutical use as absurd."

The vitamin deficiency Dr. Lonsdale is talking about: thiamin — vitamin B1, the very first vitamin ever discovered. Unknowingly, due to a shift towards high carbohydrate diets, refined sugars and availability of alcohol, beri beri, the name for vitamin B1 deficiency disease, is alive and well in the modern world even though it was thought to be conquered through food fortification decades ago.

Modern beri beri is subtle. It is not the same vitamin deficiency disease that was traced to removal of bran from polished rice decades ago and quelled with vitamin fortified foods. As Dr. Lonsdale says, modern beri beri as a disease characterized by high calorie intake and where the diet is rich in carbohydrates. It occurs in over-fed human populations. As early as 1914 it was known that the risk for beriberi increases with greater carbohydrate and sugar consumption.

Dr. Lonsdale says there are often surprisingly clear clues to the disease found in the diet. Sugary foods, particularly those with sucrose and fructose, are the primary offenders. A classic example would be a person who consumes three or four cans of soda pop a day. A shortage of vitamin B1 then results in inefficient use of oxygen in the body and tissues that require high amounts of oxygen, such as the heart and brain, suffer the most.

In fact, in virtually every nerve disorder, including multiple sclerosis and glaucoma (optic nerve) a shortage of vitamin B1 should be ruled out with a strong repeated dose of a highly absorbable form of thiamin.

In an era where modern medicine treats nearly every disease as if it were a "drug deficiency," recent studies reveal that an overlooked nutrient, vitamin B1, may have profound effect in treating or reducing the risk for major diseases such as Alzheimer's disease, diabetic-related disorders (retinopathy, neuropathy, kidney disease), and heart failure.

In 2008 researchers said: "More immediately, given the emerging multiple benefits of thiamine repletion, even mild thiamine deficiency in diabetes should be avoided and thiamine supplementation to high dose should be considered as adjunct nutritional therapy to prevent dyslipidemia (abnormal blood cholesterol) and the development of vascular complications in clinical diabetes."

One wonders about the role of thiamin deficiency not just in the prevention of diabetic complications, such a kidney, retinal and nerve damage, but in the actual onset of the disease itself.

Heart failure induced by a deficiency of thiamin is called cardiac beriberi. Anywhere from 3% to 91% of patients with heart failure are vitamin-B1 deficient. Thiamin supplementation is not widely practiced among cardiac patients despite evidence of its importance.

Many other drugs deplete vitamin B1. Included in the list are many antibiotics (penicillin, amoxicillin, ciprofloxacin, gentamycin, kanamycin, minoxycycline, neomycin, doxycycline and tetracycline). Theophylline, a drug used to treat asthma, dilantin (phenytoin), used to treat seizures, also interfere with vitamin B1.

Atrial fibrillation and vitamin B1 deficiency

Atrial fibrillation is a very common heart rhythm disorder. About 1% of American adults endure this distressing condition which is a major risk for stroke. Advancing age increases risk for atrial fibrillation. Above 80-years of age about 8-percent suffer with this problem.

This is the way a recent review article stated it: "Currently available anti-arrhythmic (anti-abnormal heart rhythm) drugs for the management of AF are not sufficiently effective and are burdened with cardiac and extra-cardiac side effects that may offset their therapeutic benefits. Better knowledge about the mechanisms underlying generation and maintenance of atrial fibrillation may lead to the discovery of new targets for pharmacological interventions."

In this era of modern medicine, treatment appears to be very crude. Drugs that inhibit blood clotting and subsequent stroke are employed at the risk of inducing hemorrhages, and as a last resort, the patient's heart tissue is intentionally destroyed by application of electrical energy (radiofrequency), leaving scar tissue behind. Ablation treatment, as it is called, is widely performed, but in this era of evidenced-based medicine, there is no evidence that ablation makes any difference in all-cause mortality. Symptoms are allayed, but does the patient live any longer?

The agonizing experience of atrial fibrillation causes this writer to look into areas not investigated by prior investigators.

Here are some pertinent facts surrounding atrial fibrillation that may help lead to an understanding of its cause:

An indirect correlation can be made between atrial fibrillation, the above listed factors, and a covert nutritional deficiency. All of the above co-factors associated with atrial fibrillation are also correlated with a shortage of thiamin — water-soluble vitamin B1.

Vitamin B1 requirements

But still, it is difficult for physicians to fathom that a shortage of a simple vitamin is what causes such widespread disease. After all, the daily requirement for vitamin B1 is just 1.5 milligrams per day, which should easily be met in a world of fortified foods and multivitamins. Furthermore, the body stores about 30-50 milligrams. But body stores can be depleted fairly rapidly, within 4-6 weeks. It is not fully appreciated that the human body's reserve pool of thiamin, can be fully depleted within days.

Taking common vitamin B1 tablets may not result in resolution of deficiency-related health problems. An obscure form of B1, the fat-soluble benfotiamine form of thiamin, is highly advised. In 1998 it was reported that benfotiamine produces 5 to 25 times greater vitamin B1 levels in the brain than plain thiamin. Over a decade has past while modern medicine has ignored this discovery. It appears that many millions of people may have prematurely become senile who could have averted their age-related brain disorder by supplementing their diet with benfotiamine.

Food fortification programs significantly reduce symptoms of beriberi, but fall short of providing complete protection from a totally preventable disease. The single greatest strike against beriberi modernus would be to fortify beer with thiamin. But this has only been mulled over. No action plans have been drawn. .

Human idiosyncrasies will likely confound the best laid plans aimed at disease prevention. Mega-dose vitamin pills will have to be designed to overcome the proclivity for alcohol and sugar, since attempts to get the public to abstain will likely fail.

The many profitable drugs that modern medicine prescribes to curb the symptoms caused by thiamin deficiency disease certainly give no incentive to properly fortify foods and provide adequate doses of thiamin in multivitamins, to get at the cause of this wide-spectrum disease.

Vitamin B1 pill should advisably be taken apart from coffee, tea or alcohol.

Outside the lens of modern medicine

America and other developed countries have developed a lifestyle that unconsciously foments a widespread shortage of vitamin B1. Because medical research focuses on minutiae rather than looking at a broader picture, a disease that is so widespread and manifests itself as many other diseases is outside the lens of modern medicine. Modern medicine is making too much money off of beri beri to cure it.

Surveys show patients themselves demand the costly high-tech care that America showcases to the world rather than 10-cent cures. When it comes to preventing beriberi modernus, it's every man for himself. Such is the current state of disease prevention in America today.