We welcome the opportunity to clarify our analysis for Dr. Rinaldo and colleagues. We modeled a pool of infective patients that included both hospitalized and nonhospitalized individuals, but calibrated the model to reproduce hospitalized cases that were accurately measured. Our analysis of vaccines and water was not intended to represent the massive and far more robust multiagency public health response to the Haitian cholera epidemic; rather, it was intended to explore the projected relative effects of low levels of vaccination and water distribution. We did not distinguish symptomatic and asymptomatic cases in our model.