Choe Son-hui has been involved in several diplomatic interactions with the US over the past decade. She is one of Kim Jong-un's top aides and analysts say her statement will have been sanctioned by the leader himself.

It came days after Mr Pence warned that North Korea "may end like Libya" - where then-leader Muammar Gaddafi was killed by rebels in 2011 after renouncing nuclear weapons eight years earlier.

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Media captionViewpoint: Why Trump's summit strategy was so unusual

Ms Choe, in an article carried by the state news agency KCNA on Thursday, said Mr Pence had made "unbridled and impudent remarks".

She added: "As a person involved in US affairs, I cannot suppress my surprise at such ignorant and stupid remarks gushing from the mouth of the US vice-president.

"Whether the US will meet us at a meeting room or encounter us at nuclear-to-nuclear showdown is entirely dependent upon the decision and behaviour of the United States."

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Media captionWhy North Korea is angry at this man: John Bolton

Meanwhile North Korea is pressing ahead with plans to dismantle its only nuclear testing facility later this week.

The Punggye-ri site is located in a remote part of the north-west of the country. A group of international journalists, who have been invited to observe the event, are on their way there.

How this story has developed

- 10 May: Trump says he will meet Kim in Singapore on 12 June

- 12 May: North Korea announces dismantling of test site

- 16 May: North threatens to scrap summit over comments by US National Security John Bolton about "Libyan model"

- 18 May: Trump distances himself from Bolton, saying US is not pushing for Libya-style denuclearisation

- 22 May: Trump insists that unless the US gets "certain conditions... we won't have the meeting"

'Careful diplomacy requires careful messaging'

Analysis from Laura Bicker, BBC News, Seoul

So we are back to name calling and threats of nuclear war - just weeks before the planned summit.

Some may say this is a typical Pyongyang power play. But it was also so avoidable.

North Korea had made it clear last week that mentioning the Libyan model of denuclearisation touched a nerve. Firstly because the Gaddafi regime collapsed and he was killed, but also because the North believe its weapons programme is far more advanced than Libya's ever was.

So to even mention the two countries in the same context will be a grave insult and Pyongyang may feel that Washington is not showing it the respect it deserves.

The US had been warned, and yet Mr Pence decided to repeat the comparison anyway. Careful diplomacy requires careful messaging and careful language, and North Korea clearly feels the Trump administration has shown a lack of discipline in this regard.

It is interesting that Pyongyang decided not to target Donald Trump, who also made similar remarks. Aiming the insults at those around the president rather than Mr Trump himself may suggest North Korea is not ready to throw away the prospect of a summit quite yet.