The IgG fraction of culture supernatant was purified by Protein G affinity chromatography

Specifications: c-Kit antibody [14G5]

Full Name

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Product Description

Mouse Monoclonal antibody [14G5] to c-Kit

Background

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]