Results: :
Up to 747 different sites of the SIV integration were sequencedand mapped in human genome. SIV-hPEDF favored gene-dense regionsand transcription units of the genome for integration. Integrationin cancer-related genes or that near their promoters was observed,however, there was no particular preference for the integrationto them.

Conclusions: :
Our data indicate that the integration site preferences of ourSIV-hPEDF show much the same tendency of other lentiviral vectors,which were previously reported.