I woke up this morning and Murphy has lost a lot of his color. I noticed his gills were red a couple of days ago, but thought nothing of it. I have been treating Murphy with Maracyn and Epsom since Saturday. I have already ordered Kanaplex and expect it to be here tomorrow. I was treating him because of fin rot.
Please help :( I don't know what to do... and honestly I'm out of resources. I've already spent $60 on Murphy since Saturday.

Housing
What size is your tank? 5 GallonWhat temperature is your tank? 79 degrees
Does your tank have a filter? No
Does your tank have an air stone or other type of aeration? Yes
Is your tank heated? Yes
What tank mates does your betta fish live with? None

Food
What type of food do you feed your betta fish? Omega One Betta Buffet and Bloodworms on occasion.How often do you feed your betta fish? Once a day except Sundays
Maintenance
How often do you perform a water change? 100% weekly and 50% mid week.
What percentage of the water do you change when you perform a water change? 50% - 100%
What type of additives do you add to the water when you perform a water change? API Stress coat, API water conditioner. Also I have been adding Maracyn and Epsom to treat his fin rot.

Water Parameters:
Have you tested your water? If so, what are the following parameters?I have not tested my water, but I did a 100% water change Saturday and added water conditioner, stress coat, epsom, and Maracyn.

Symptoms and Treatment
How has your betta fish's appearance changed? He has lost alot of his color just since last night.
How has your betta fish's behavior changed? He seems the same, just staying in the corner of the tank.
When did you start noticing the symptoms? TodayHave you started treating your fish? I already have him in Epsom and Maracyn for fin rot.
Does your fish have any history of being ill? YesHow old is your fish (approximately)? 8-12 months

The red coloring on his face could indicate ammonia burns but from your water change description I doubt it. Could also have been septicemia.. you see similar color pattern. You had some very aggressive bacterial infection of some sort we knew going into to trying to treat because it had already a chunk of his face which is why you were skipping salt treatment..when you get something that aggressive sometimes the meds just don't have time to take hold.

I was thinking Septicemia also because his whole body eventually turned that red color. I'm not sure... It's just so wild how quickly this all happened. He was fine at 2am and by 7am he had totally changed. I feel so bad for the poor guy. For the first 2 days he was doing great, I was so hopeful :( He isn't in any pain anymore.