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Ephrin A3 ELISA Kits (EFNA3)

On www.antibodies-online.com are 13 Ephrin A3 (EFNA3) ELISA Kits from 6 different suppliers available. Additionally we are shipping Ephrin A3 Antibodies (49) and Ephrin A3 Proteins (16) and many more products for this protein. A total of 90 Ephrin A3 products are currently listed.

Results demonstrate that neurons expressing different odorant receptors express different levels of ephrin-A3 and -A5 protein (show NRP1 ELISA Kits) on their axons.

In mice deficient for ephrin-A2, A3 and A5, eye-specific inputs segregated but shape and location of eye-specific layers were profoundly disrupted. Ephrin-As and neural activity act together to control patterning of eye-specific retinogeniculate layers.

Human Ephrin A3 (EFNA3) interaction partners

Results show that EFNA3 serves as a tumor suppressor in malignant peripheral nerve sheath tumor cells and it may play a critical role in the FAK signaling and VEGF-associated tumor angiogenesis pathway.

The interaction between ephrin-As, Eph (show EPHA1 ELISA Kits) receptors and integrin alpha3 is plausibly important for the crosstalk between Eph (show EPHA1 ELISA Kits) and integrin signalling pathways at the membrane protrusions and in the migration of brain cancer cells.

EphA2 (show EPHA2 ELISA Kits)/ephrin-A3 interactions may play a role in the localization and network of Langerhans cells in the epithelium and in the regulation of their trafficking.

Ephrin A3 (EFNA3) Antigen Profile

Antigen Summary

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin.