The posterior localization of oskar protein in the posterior
pole of drosophila embryos is requested to direct the
deployment of nanos, the posterior body patterning morphogen
in Drosophila. The regulation mechanism involves translation
repression of oskar mRNA prior to its localization at the
posterior pole of the oocyte. Translation repression is
mediated by the ovarian protein bruno that binds specifically
to a cis-acting element located in the the 3'UTR of the
oskar mRNA made ......