The Final Showdown

The mission is initiated by speaking to a policeman in the plaza in front of HQ after completing the Zero Point Power Up mission. Once the mission has been initiated, vehicles (including the Incredicopter) will not be available for use, though Packs will.

The Incredible must first locate Syndrome by following the arrows. It is not a simple path to reach him, and it requires scaling a building across the street and down a ways (look for a the blue glass building), crossing the street by rail-riding a cable, and launching the Hover Board of a ramp-like roof access door so that it can get enough height to fly across to the next building.

Once the correct roof has been reached, a cut scene will launch as Syndrome make his final confrontation.

The Incredible will stay on one rooftop while Syndrome stays on the roof directly across, hurling energy bolts at the Incredible. Omnidroids will spawn on the Incredible's roof, which the Incredible must pick up with the Zero Point Energy Gauntlet and hurl at Syndrome. Knock Syndrome down three times and he'll fall off the roof, after which he'll return with heavier Omnidroids. Repeat this process two more times to defeat Syndrome and end the mission (and the main story). Keep in mind that the Gauntlet requires that the character be very close to whatever is being picked up, and also requires accurate aim to throw the droids at Syndrome.

Note: If the Incredible falls off the roof, the gameplay should reset. It is possible though to hit the ground - this seems to be a glitch from which there is no way to get back up without quitting out of the game.