In a collaborative and highly interdisciplinary effort, the Wang, Warren, Malcolmson, Blum, and Theis labs have disclosed a new class of molecules that may be used as biomolecular tags for MRI, potentially enabling metabolic processes to be viewed in real time. The work, published in the journal

Charbonneau and collaborators have recently made the stunning prediction that, upon cooling, simple glass-forming liquids can form two different types of amorphous solids. This work and the broader scientific context for this fundamental advance is featured this month in the French popular scien

The Hargrove lab discusses progress towards the molecular characterization of long noncoding RNAs (lncRNAs), a relatively new class of biomacromolecules implicated in a wide range of biological processes and human diseases.

A new review from the McCafferty lab focuses on KDM1 class lysine demethylases. These enzymes are integrally involved in many biological processes and diseases and are therefore promising therapeutic targets.

Researchers in the McCafferty Lab have recently designed a mutant enzyme that shows promise as a molecular probe. This engineered enzyme is a mutant of lysine–specific demethylase 1A (KDM1A/LSD1), an epigenetic target with therapeutic potential.