Storage & Safety

Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance

Microtubule-associated proteins 1A/1B light chain 3 beta 2, also as known as MAP1LC3B2, belong to the MAP1LC3 family. MAP1LC3B2 is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. This protein probably is involved in formation of autophagosomal vacuoles (autophagosomes). It is expressed primarily in heart, testis, brain and skeletal muscle and testis. Recombinant human MAP1LC3B2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.