He was asked on Bloomberg TV's "Political Capital With Al Hunt" about the impracticality of fully repealing Obamacare now that more than 7 million people have signed up on the insurance marketplaces, and more are benefiting from other provisions.

"I'd question the premise of that entire argument. No, I don't know that [we can't repeal it]," Ryan said in the interview, which is set to air Friday night. "So this whole thing that, oh, we have 7.1 million people, which, by the way, we won't even get into the legitimacy of that statistic. So we have -- let's just take it for argument. Seven million people on Obamacare; there's no way you can change it. It's just going to have to learn to live with it. I don't buy that for a second."

Ryan, asked if the next president will repeal Obamacare, said he doesn't think the law "can last" and posited that "the architecture of this law is so fundamentally flawed that I think it's going to collapse under its own weight."