Description

Zoxil CV (500/100 mg) Injection is a combination medicine used to treat a variety of bacterial infections. Amoxycillin interferes with the growth and division process of the bacterial cell wall while clavulanic acid ensures extended anti-bacterial activity. This combination is used to treat bacterial infections of the lungs and airways, middle ear, sinuses, skin, bone and joints, and the urinary tract.

Uses of Zoxil CV (500/100 mg) Injection

What is it prescribed for?

Ear Infection (Otitis Media)

This medicine is used to treat infections of the middle ear caused by bacteria.

Nose Infection (Sinusitis)

This medicine is used in the treatment of infections of the nose and nasal chamber caused by bacteria.

Throat Infection (Tonsillitis/Pharyngitis)

This medicine is used in the treatment of infections of the throat and airways leading to lungs, namely Tonsillitis and Pharyngitis caused by bacteria.

Lower Respiratory Tract Infection

This medicine is used in the treatment of infections of the airways leading to the lungs. The infections can be Pneumonia, acute bronchitis, or others caused by different bacterial strains.

Skin Infection

This medicine is used in the treatment of infections of the skin and skin structures caused by bacteria.

Urinary Tract Infection

This medicine is used in the treatment of infections of the bladder (Cystitis) and kidneys (Pyelonephritis).

Infections associated with surgical procedures

This medicine is used to prevent possible infections associated with major surgical procedures such as joint replacement surgery, biliary tract surgery, etc.

Bone and joint infections

This medicine is used for the treatment of infections of the bones and joints (Osteomyelitis) caused by Staphylococcus aureus.

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Side effects

Major & minor side effects for Zoxil CV (500/100 mg) Injection

Allergic Skin Reactionsevere

Diarrheasevere

Feversevere

Joint pain

Skin yellowing

Easy bruising and bleeding

Heavy menstrual bleeding

Tooth discoloration

Nausea or vomiting

Altered sense of tasterare

Convulsionssevererare

Painful intercoursesevererare

Swelling of face, lips, eyelids, tongue, hands and feet severerare

Black or tarry stoolsrare

Muscle or joint pain

Sleeplessness

Irregular heartbeatrare

SEVERE

Contact your doctor immediately if any of these symptoms are experienced on a regular basis.

RARE

Observed in a small fraction of population.

This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

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Highlights

Commonly asked questions for Zoxil CV (500/100 mg) Injection

Onset of action

The effect of this medicine can be observed within 1-2 hours of administration.

Duration of effect

The effect of this medicine lasts for an average duration of 6-8 hours.

Safe with alcohol?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?

No habit forming tendencies were reported.

Usage in pregnancy?

This medicine should be used in pregnant women only if the need is clearly established and the benefits outweigh the risks. Consult your doctor before using this medicine.

Usage while breast-feeding?

This medicine should be used in breastfeeding women only if the need is clearly established. Consult your doctor before using this medicine.

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When not to use?

Contraindications of Zoxil CV (500/100 mg) Injection

Allergy

This medicine is not recommended for use if you have a known history of allergy to Amoxycillin or Clavulanic acid derivatives. Do not consume this medicine if you have a known history of allergy to Penicillins or Beta lactam antibiotics.

Cholestasis

This medicine is not recommended for use if you have had a condition where the normal flow of bile from the liver is interrupted (cholestasis).

Liver dysfunction

This medicine is not recommended for use if you have a history of liver dysfunction associated with the use of these medicines in combination.

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Dosage

Missed Dose

Since this medicine is administered in a clinical or a hospital setup, the likelihood of a missed dose is very low. Contact your doctor immediately if you have missed a scheduled dose of this medicine.

Overdose

Since this medicine is administered in a clinical or a hospital setup, the likelihood of an overdose is very low. However, if an overdose of this medicine is suspected, your doctor will initiate emergency medical treatment. Symptoms of an overdose may include nausea, vomiting, diarrhea, drowsiness, etc.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

- Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

- Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Disease interactions

Mononucleosis

moderate

This medicine is not recommended for use in patients with a history of mononucleosis since these patients may develop a skin reaction/eruption. Replacement with a suitable alternative should be done under your doctor's supervision.

Colitis

moderate

This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis. Inform your doctor if you have any history of gastrointestinal diseases. Report any incidence of severe diarrhea, abdominal pain, and blood in stools to the doctor immediately. Replacement with a suitable alternative may be necessary based on the clinical condition.

Renal Diseases

moderate

This medicine should be used with caution in patients with a history of renal diseases or active renal diseases. Close monitoring of the renal function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative might be required in some cases based on the clinical condition.

Food interactions

Information not available.

Lab interactions

Urine Sugar Test (Benedict's of Fehling's reagent)

moderate

Report the use of this medicine prior to the test. This medicine may give a false positive result for the presence of glucose/sugar in the urine. The urine sugar test should be performed with a different reagent in case you are receiving this medicine.

This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Administer Zoxil CV (500/100 mg) Injection exactly as prescribed by the doctor. It is recommended to take this medicine under the supervision of a doctor or a trained healthcare professional.

Warnings

Warnings for special population

Pregnancy

- This medicine should be used in pregnant women only if the need is clearly established and the benefits outweigh the risks. Consult your doctor before using this medicine.

Breast-feeding

- This medicine should be used in breastfeeding women only if the need is clearly established. Consult your doctor before using this medicine.

General warnings

Allergic Reaction

- This medicine is likely to cause moderate to severe allergic reaction and the likelihood is very high in patients who are known to have an antibiotic allergy. Report the occurrence of any such reaction to the doctor on priority.

Diarrhea

- Use of this medicine is likely to cause diarrhea. It may be a mild episode requiring no specific treatment or a severe case of colitis or Clostridium Difficile-Associated Diarrhea (CDAD). Chances of occurrence are very high in patients having a history of diarrhea after using antibiotics. All such instances should be reported to the doctor on priority.

Mononucleosis

- This medicine is not recommended for use in patients with Mononucleosis. This medicine is likely to cause rashes and bumps on the skin if the patient is suffering from Mononucleosis.

Drug-resistance

- Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Liver disease

- This medicine should be used with caution in patients having an impairment of the normal liver function. It is advised to regularly monitor the liver enzyme levels while taking this medicine and even after treatment with this medicine is complete.

Form and method of administration

- This medicine is generally administered either by slow intravenous injection over a period of 3-4 minutes or by intravenous infusion over a period of 30-40 minutes. It is not suitable for intramuscular administration. The patient should be shifted to oral forms as soon as possible.

Other details

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works

Amoxycillin binds to certain specific receptors and prevents the formation of a necessary component for cell wall building process. Clavulanic acid is effective against a specific species of bacteria that are resistant to other antibiotic medicines. Thus, the combination becomes effective against an extended range of bacteria.

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&Chere.