Box Office: ‘Neighbors’ Is Life of the Party Friday, Taking No. 1 Spot From ‘Spider-Man 2’

The Seth Rogen and Zac Efron comedy chugged its way to $19.6 million Friday, heading for $48-$49 million in its domestic debut.

Neighbors, the R-rated comedy starring Seth Rogen and Zac Efron as feuding next door neighbors, partied its way to a stellar $19.6 million Friday, and is on its way to unseating holdover Amazing Spider-Man 2 for the top spot at the domestic box office.

Directed by Nick Stoller, the filmmaker behind Forgetting Sarah Marshall and The Five-Year Engagement, Neighbors is likely to earn an outstanding $48 million to $49 million in its U.S. debut, while the Andrew Garfield-starring Spidey sequel, which earned $10.1 million Friday, is expected to gross $36 million to $37 million for the Mother’s Day weekend.

Opening in 3,279 theaters, Neighbors, which was doing strong advanced ticket sales ahead of the weekend, was produced by This Is the End team Rogen, Evan Goldberg and James Weaver.(Rogen and Goldberg also directed that 2013 end-of-the-world comedy.) The trio is producing Neighbors alongside Nathan Kahane and Joe Drake‘s Good Universe banner. The R-rated Universal film follows a young couple (Rogen and Rose Byrne) with a new baby, whose quiet suburban lifestyle is ruined when a rowdy frat moves in next door.

The raunchy comedy also opened in 29 international territories and it is No. 1 in 16 territories. In the U.K. and Ireland, the film opened No. 1 with a 46 percent market share. Through Friday, its box office total is an estimated $10.4 million (£6.1 million) at 500 dates including some previews. The film is also No. 1 in Australia with 50 percent market share with a total after two days plus last weekend’s previews is $4.3 million.

Sony’s Spider-Man sequel, now in its second weekend and playing in 4,324 locations, should have a new domestic cume of around $147 million by Sunday, but is seeing a drop of nearly 60 percent in its second weekend.

The film, also starring Emma Stone and Jamie Foxx, grossed $91.6 million in North America last weekend and has collected north of $450 million globally. It will continue to do strong business overseas this weekend.

Faith-based comedy Mom’s Night Out, starring Patricia Heaton, earned $1.25 million Friday, putting the film on its way to between $4 million and $5 million for the weekend. The religious audience who flocked to see such recent faith-based dramas as God’s Not Dead and Heaven Is for Real does not seem to be supporting the new TriStar Pictures comedy — about a stressed-out mother of young children (Sarah Drew) who attempts an outing with other moms from the same congregation — in the same way.

Independent animated film Legends of Oz also opened this weekend in 2,525 locations, but the family film is falling flat at the domestic box office, earning just $981,000 Friday. U.S. distributor Clarius Entertainment hopes that Mothers Day will lead to more families heading into theaters to see the film, but several box office observers have the 3D film debuting to a soft $4 million in the U.S.