The United States Senate elections, 1994 was an election held on November 8, 1994, in which the Republican Party was able to take control of the Senate from the Democrats. In a midterm election, the opposition Republicans held the traditional advantage. Congressional Republicans campaigned against the early presidency of Bill Clinton, including his unsuccessful health care plan.[citation needed]

The Republicans successfully defended all of its seats and captured eight seats from the Democrats, including the seats of sitting Senators Harris Wofford (PA) and Jim Sasser (TN), as well as six open seats in Arizona, Maine, Michigan, Ohio, Oklahoma, and Tennessee. Notably, since Sasser's defeat coincided with a Republican victory in the special election to replace Al Gore, Tennessee's Senate delegation switched from entirely Democratic to entirely Republican in a single election.

Ted Kennedy usually coasted to re-election, but in this election he faced an unusually tough challenge from Republican businessman Mitt Romney. Though the final result was a 17-point Kennedy victory, it marked the first time since his initial election in 1962 that Kennedy received less than 60% of the vote.

Democrat Harris Wofford was appointed to the Senate when three-term Republican Senator H. John Heinz III died in a 1991 plane crash. He won a special election to hold that seat later that year. In his tough re-election against Republican Congressman Rick Santorum, the pro-choice Wofford lost the endorsement of pro-life Democratic Governor Robert Casey. This contributed to his loss to Santorum by two percentage points.

One of the biggest upsets of the night was the defeat of three-term incumbent Senator Jim Sasser. Sasser had been the influential Chairman of the Budget Committee and was among the leading candidates to replace Mitchell as Democratic Floor Leader. Sasser, however, would be defeated by prominent Nashville heart surgeon Bill Frist by a margin of 14 points.

Less surprising was the Republican victory in the other Tennessee Senate contest. Harlan Matthews had held the seat since Al Gore's resignation to assume the Vice Presidency in 1993, but chose not to seek the Democratic nomination in the special election. The Republican nominee, actor and attorney Fred Thompson, defeated six-term Democratic Congressman Jim Cooper in an overwhelming landslide.

Democrat Chuck Robb received over 70% of the vote when first elected in 1988, but struggled to win re-election. Furor over Robb's alleged affair with model Tai Collins provided plenty of momentum for the Republicans nominee, Iran-Contra figure Oliver North. A factor to Robb's advantage was the independent candidacy of attorney J. Marshall Coleman. North likely lost votes to Coleman especially when Virginia's other Senator, Republican John Warner, endorsed Coleman over North. Robb received 46% of the vote to North's 43% with Coleman garnering 11%.