Gene expression data from microarrays are being applied to predict preclinical and clinical endpoints, but the reliability of these predictions has not been established. In the MAQC-II project, 36… (More)

Epigenetic mechanisms have been proposed to play crucial roles in mammalian development, but their precise functions are only partially understood. To investigate epigenetic regulation of embryonic… (More)

Pre-computed data cube facilitates OLAP (On-Line Analytical Processing). It is a well-known fact that data cube computation is an expensive operation, which attracts a lot of attention. While most… (More)