Abstract

It is a common observation that patients with pernicious anemia may fail to respond to the oral administration of liver, liver extract and ventriculin, and that these same patients will respond promptly to an extract given intramuscularly. Satisfactory and more rapid improvement in the patient's blood has been frequently noted after intravenous injection of specially prepared liver extract.1, 2, 3, 4, 5 However, this intravenous therapy is not in general use because of the side reactions noted in many cases.

The case of pernicious anemia reported in this paper is of interest because on the first admission the patient responded