Although the immunopathology of chronic chagasic cardiomyopathy (CCC) caused by Trypanosoma cruzi is poorly understood, cytokines are likely to play a role in its mediation. The Cebus apella monkey is a good model system for Chagas' disease, since...

The mechanisms of protection and pathogenesis in malaria are not well understood. Antibodies to sporozoites and asexual erythrocytic stages of the parasite antigens have been shown to have a protective role in experimental model. In human P....