Synthetic peptide unique to PAC9 protein was used to generate antibodies in rabbit. (unfortunately, the amino acid sequence is considered to be commercially sensitive). All peptides were amidated before conjugation.

Applications

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application

Abreviews

Notes

WB

1/500. Detects a band of approximately 110 kDa (predicted molecular weight: 150 kDa).

Target

FunctionMay play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin.

Tissue specificityExpressed in multiple cells of the lung, with expression highest in airway smooth muscle.