Compare Skelaxin vs. Valium

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Skelaxin (metaxalone) is used for muscle spasms and musculoskeletal pain with mixed results.

Helps you relax.

Valium (diazepam) is effective for occasional or short-term use for anxiety and muscle spasm. Compared to similar drugs, Valium (diazepam) acts very quickly but can have interactions with other medicines.

●●●●●

3.8/ 5 average rating with 976 reviewsforValium

Upsides

Can be used for muscle spasms and muscle pain if other medications have not worked.

Available as generic.

Slightly less sedation and side effects compared to other muscle relaxants.

Valium (diazepam) effectively relieves anxiety and muscle spasms.

Valium (diazepam) has less severe withdrawal symptoms compared to other similar drugs.

Works very quickly.

Available in generic.

Downsides

Effects don't last that long. You need to take Skelaxin (metaxalone) up to 3-4 times daily.

Several studies showed mixed results when Skelaxin (metaxalone) was compared with a sugar pill for treatment of muscle spasms and musculoskeletal pain.

Can make you very drowsy or sleepy

Even though a generic is available, it is still fairly expensive.

Use of Valium (diazepam) can cause memory problems, drowsiness, dizziness, and confusion.

Valium (diazepam) can be habit-forming, so it's not typically used for long-term treatment.

Most people find that their body will get used to Valium (diazepam) levels and they may need higher doses over time to achieve the same effect.

People with severe liver problems should not take Valium (diazepam). Several drugs can also interfere with how Valium (diazepam) works.