The protein encoded by ABCG4 is included in the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCG4 Kits (8) and ABCG4 Proteins (3) and many more products for this protein.

ABCG1 (show ABCG1 Antibodies) and ABCG4 act in concert with ABCA1 (show ABCA1 Antibodies) to maximize the removal of excess cholesterol from cells and to generate cholesterol-rich lipoprotein particles

based on the results, we propose that ABCG1 (show ABCG1 Antibodies) and ABCG4 mediate the intracellular vesicular transport of cholesterol/sterols within both neurons and astrocytes to regulate cholesterol transport in the brain

a role for Abcg4 in sterastrocyol efflux in the brain, Abcg4 promotes efflux of cholesterol, desmosterol, and possibly other sterol biosynthetic intermediates to HDL (show HSD11B1 Antibodies).

ABCG4 Antigen Profile

Protein Summary

The protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily and is expressed predominantly in liver tissue. The function has not yet been determined but may involve cholesterol transport. Alternate splice variants have been described but their full length sequences have not been determined.