Given a threshold on the posterior probabilities, genes are declared as null or differentially expressed. For any given threshold, the FDR (false discovery rate) and FNR (false non-discovery rate) can be estimated using the posterior probabilities. Estimated numbers of false positives and false negatives are also output.

Modify several different aspects of a binary sequential boundary.
Most modifications do not change the stopping boundaries. The exceptions are 'missN', which allows modifications for missing assessments,
and 'closeout', which allows for early stopping of the trial for administrative reasons (i.e., reasons that do not depend on the responses in the trial).
Other modifications possible: level of the confidence intervals (using tsalpha, conf.level, or alternative), which boundaries are binding (i.e., can change from a boundary with binding futility boundaries to one with
non-binding futility boundaries), null hypothesis value (theta0), and whether the confidence intervals should match the non-binding futility p-values on the superiority boundaries (cipMatch).