Further Information

DMSO, Methanol. The solubility of 17-AAG in DMSO is >10 mM. General tips for obtaining a higher concentration: Heating to 37°C and using ultrasonic bath is advisable.

Compound Classification:

Benzoquinone ansamycin antibiotic.

Geldanamycin derivate.

HSP90 inhibitor.

Storage, handling:

Store in a freezer upon arrival, at -10°C to -25°C

Use the original container to store the product.

Keep the lid tightly closed.

Avoid exposing to strong direct light.

Applications:

This compound was mentioned as an anticancer medicine. Geldanamycin derivates all interfere with heat-shock proteins, especially HSP90. 17-AAG belongs to a class of drugs called heat shock protein 90 (Hsp90) inhibitors.