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Thank you to the excellent team assembled by McGraw-Hill to complete this textbook: to our development editor, Susan Kelly, for her rare mastery of the details and the Big Picture, all at the same time; to the artist, Matt Chansky, for turning our scribbles into real art and for being patient with all of our changes; and to Karen Davis and Michael Weitz for keeping us all on task. Particular thanks to our student reviewers James Thorburn, Aiden Brazil, and Brendan Sheehan for their excellent feedback, and to the Memorial University Medical School Class of 2011 for helping us to decide on which features to include in the book.