anti-H2A Histone Family, Member Y (H2AFY) Antibodies

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Additionally we are shipping H2AFY Proteins (8) and many more products for this protein.

H2AFY Antibodies by Reactivity, Application, Clonality and Conjugate

More product categories related to H2AFY Antibody

Top referenced anti-H2AFY Antibodies

Chicken Polyclonal H2AFY Primary Antibody for WB - ABIN2787623
:
Bernstein, Muratore-Schroeder, Diaz, Chow, Changolkar, Shabanowitz, Heard, Pehrson, Hunt, Allis: A phosphorylated subpopulation of the histone variant macroH2A1 is excluded from the inactive X chromosome and enriched during mitosis. in Proceedings of the National Academy of Sciences of the United States of America 2008
(PubMed)

More Antibodies against H2AFY Interaction Partners

Human H2A Histone Family, Member Y (H2AFY) interaction partners

The Skp2-mH2A1-CDK8 (show CDK8 Antibodies) axis has a critical role in breast cancer development via dysregulation of the G2/M transition, polyploidy, cell growth dysregulation, and loss of tumor suppression.

We show that composite nucleosomes containing mH2A and NRF-1 (show NFE2L1 Antibodies) are stably positioned on gene regulatory regions and can buffer transcriptional noise associated with antiviral responses

High MacroH2A1 expression is associated with epigenetic markers for activation of lipogenic genes in fat-induced steatosis.

The Skp2-mH2A1-CDK8 (show CDK8 Antibodies) axis has a critical role in breast cancer development via dysregulation of the G2/M transition, polyploidy, cell growth dysregulation, and loss of tumor suppression.

macroH2A may help maintain the long-term stability of the differentiated state of somatic cells.

H2AFY Antigen Profile

Protein Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.