Saccharin to Treat Cancer

Are you sweet enough? Maybe you are if you use saccharin. But wait! Are there other uses that this comforter can be used for? Scientists believe that it could treat cancer. The saccharin molecule deactivates carbonic anhydrase IX, a protein in aggressive cancers.

Carbonic anhydrase IX regulates PH so that cancer can more easily spread through the body. It is hoped that saccharin can change the PH level. If it is not at an optimum level the cancer can be successfully treated with radiation and chemo therapy.

Healthy tissues, except for the gastrointestinal tract, have no carbonydrase anydrose IX. Other carbonic anydrase proteins are there though. Molecules tested before blocked similar carbonic anydrase proteins which are present to make the body work. By tweaking the saccharin molecule it was discovered that it does not affect helpful anhydrase proteins.

Tests have begun on liver and breast cancer. These are currently on animals. If the research is successful work on humans will open a new road to treating aggressive cancers.