The Wood Library-Museum

Benzocaine

German chemist Eduard Ritsert (1859-1946) was one of many who joined in the search for a non-addictive substitute for cocaine. In 1900, he synthesized benzocaine, a derivative of the organic compound para-aminobenzoic acid (PABA). Two years later, he introduced benzocaine under the name “Anaesthesin” (also called Anesthesine). In 1903 he patented his formula, and founded a company to manufacture and sell it. Benzocaine is a weak local anesthetic and has been used primarily as an external pain reliever. It is an ingredient in numerous commercial products for application on the skin, as well as in the ears, and mouth. The “Benzocaina” brand was made by the English pharmaceutical and surgical equipment maker, Allen & Hanburys. The use of benzocaine in topical analgesics has declined because, like the PABA from which it is derived, it can cause allergic reactions.

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