..Unlike in a bet-hedging strategy, we observe that cells with a higher investment in maintenance, measured as the basal RpoH transcriptional activity prior to antibiotic treatment, are more likely to give rise to stressed, frail progeny...

Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenation

..The identification of these two mutants implies that reducing mortality is not impossible; rather, due to its cost, it is subject to trade-offs with other traits that contribute to the competitive success of the organism...

Dissecting the genetic components of adaptation of Escherichia coli to the mouse gut