chancre

chancre:

see syphilissyphilis, contagious sexually transmitted disease caused by the spirochete Treponema pallidum (described by Fritz Schaudinn and Erich Hoffmann in 1905). Syphilis was not widely recognized until an epidemic in Europe at the end of the 15th cent......Click the link for more information..

chancre

[′shaŋ·kər]

(medicine)

A lesion or ulcer at the site of primary inoculation by an infecting organism.

The initial lesion of syphilis.

chancre

Pathol a small hard nodular growth, which is the first diagnostic sign of acquired syphilis

Adding to the frustration, syphilis itself may be asymptomatic during many stages of the disease or the present chancres are painless, atypical, or located in an inconspicuous anatomical site, thus confounding the clinical diagnostic capabilities (19).

Syphilitic chancres often mimic other genital ulcers, including those caused by different sexually transmitted diseases such as chancroid (as a result of infection with Haemophilus ducreyi) or granuloma inguinale (Klebsiella granulomatis).

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