ULTRASONIC NEUROMODULATION

Academic interests in how micromechanical forces regulate synaptic physiology and plasticity led us to begin pioneering methods and devices for noninvasively stimulating brain circuits using low-intensity, low-frequency pulsed ultrasound about a decade ago. Our primary observations that the mechanical forces exerted by low-intensity pulsed ultrasound can safely and directly stimulate action potentials and synaptic transmission in intact brain circuits spawned new lines of research by laboratories around the world to study and develop ultrasound for noninvasive neuromodulation. Work on cellular mechanisms of action continues alongside our translational efforts aimed at modulating intact deep-brain limbic circuitry in humans. See Ultrasonic Neuromodulation and Neuromechanobiology.

ELECTRICAL NEUROMODULATION

In addition to developing noninvasive neural interfaces using pulsed ultrasound, we also engineer neuromodulation methods and devices that implement high-frequency, pulsed electrical currents delivered to peripheral and cranial nerves. More Info

NEUROMODULATION FOR HUMAN PERFORMANCE ENHANCEMENT

OUR PURPOSE IS TO EXPAND HUMAN POTENTIAL

We focus our applied research efforts on establishing new boundaries for human performance by creating, studying, and iteratively optimizing ultrasonic and electrical neuromodulation technologies. Our lab serves an established leader role by developing these neuromodulation platforms, testing and evaluating neuromodulation device/protocol safety and efficacy, and globally deploying neuromodulation systems intended to enhance brain health and human performance in healthy individuals and elite athletes. More Info