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It's unclear how long he might be sidelined. Dorsey left Friday's practice with the injury. Dorsey reportedly had torn his biceps and would need an operation.

It is not known if Dorsey, injured on his 29th birthday, will miss the entire upcoming season as more evaluations still must be done. A decision about Dorsey's status is expected to be made after surgery on Monday, nbcsports.com reported.

The Niners had a day off from training camp Saturday.

Losing Dorsey would be a huge blow 11 months after starting nose tackle Ian Williams went down with a season-ending ankle injury in a Week 2 loss at Seattle. Dorsey quickly emerged as a reliable replacement and stabilizing force for the defensive line.

Williams has had multiple surgeries and is currently on the physically unable to perform list. Mike Purcell, an undrafted free agent last year, could be an immediate option to fill the void left by Dorsey as the 49ers prepare for their preseason opener Thursday at Baltimore.

Dorsey, the No. 5 overall pick in the 2008 draft for the Chiefs, appeared in 16 regular-season games with 13 starts last year. In 2013, Dorsey signed a two-year contract that could pay him up to $7 million with incentives.

THOUSANDS SEE MANZIEL: An announced crowd of 20,673 fans came to InfoCision Stadium at the University of Akron to see Johnny Manziel and Brian Hoyer continue their competition for the Browns starting quarterback job. Manziel worked only with Cleveland's second-string offense in the scrimmage, while Hoyer worked with the first unit. The 2012 Heisman Trophy winner completed 3-of-7 passes for 14 yards with runs of 9 and 5 yards. "It felt good to run," said Manziel. "And I think the plays we executed on those worked really well." Manziel described his rookie growing pains and attempt to learn the intricacies of the playbook as "a struggle" last week. "There's no gap that I'm looking at right now," Manziel said after the scrimmage. "It's know the playbook, know everything. There's still so many little things here and there that can throw a play and change a play and a defensive look, and that's stuff that I wasn't used to. Now I'm seeing it, adjusting, learning."

JAGUARS: Former Florida State receiver Kenny Shaw signed with the team. Shaw, who had 54 receptions for the Seminoles in his senior season, was signed as an undrafted rookie by the Browns in May and waived last month.

DOLPHINS: Center Samson Satele signed with the team and guard Samuel Longo was waived. Satele previously played with the Dolphins in 2007-08, and was with the Colts last season.