Owen Wilson and Vince Vaughn are an unbeatable combination as two Washington DC lawyers who get their kicks, and their girls, by crashing weddings. Displaying talent, wit, intelligence, and ample charm, the pair seldom fails at their mutual mission of seduction. But eventually they get bored with the routine. Everything explodes when they crash an upper-crust wedding given by US Senator William Cleary (Christopher Walken). Jeremy (Vaughn) makes the ostensible mistake of seducing Cleary's sexually ravenous daughter Gloria (Isla Fisher) and John (Wilson) falls head over heels for the beautiful, slightly sarcastic older sister, Claire (Rachel McAdams). But Claire is nearly engaged to a slimy, macho, ivy-league snob played with beady-eyed gusto by ALIAS's Bradley Cooper. The boys get lured away on a weekend trip to the Cleary's estate, which is when the film begins to resemble an early 1930s pre-code comedy with its innuendo-filled banter, eccentric grandmothers, suspicious rivals, and copious bed-hopping.

Vaughn's motor-mouth aggression plays off Wilson's irresistible sensitivity (and vice versa) to such perfection that they leave other contemporary romantic comedy teams in the dust. They manage to get plenty of laughs and warmth from their believably close male friendship without resorting to any clichéd homoerotic references. Their respective love interests are also outstanding, particularly McAdams who displays extraordinary wit and presence in addition to her stunning beauty. Walken is surprisingly low-key as the senator, tuning his usual craziness down to a few tensile stares. Seventies mini-series staple Jane Seymour is memorable as the senator's sex-starved, boozed-up wife, who makes a play for John.