Sandro ruled out of Tottenham's pre-season tour

In demand: Sandro has been linked with a move away to Italian side Napoli

Brazilian midfielder Sandro has been withdrawn from Tottenham's squad for the pre-season tour of the United States and Canada because of a virus, the Barclays Premier League club confirmed.

Spurs have headed across the Atlantic for matches against Major League Soccer sides the Seattle Sounders, Toronto FC, where they should face former striker Jermain Defoe, and the Chicago Fire as new manager Mauricio Pochettino looks to assess the squad ahead of his first season at White Hart Lane.

Football's twitterati - Top 10 most followed Premier League clubs on twitter (December 2014)

Football's twitterati - Top 10 most followed Premier League clubs on twitter (December 2014)

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10. Aston Villa (@AVFCOfficial) - 359K

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9. West Ham United (@whufc_official) - 372K

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8. Newcastle United (@NUFC) - 479K

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7.Everton (@Everton) - 486K

LIVERPOOL, ENGLAND - APRIL 20: Kevin Mirallas of Everton celebrates scoring their second goal during the Barclays Premier League match between Everton and Manchester United at Goodison Park on April 20, 2014 in Liverpool, England. (Photo by Alex Livesey/G

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6.Tottenham (@SpursOfficial) - 980K

LONDON, ENGLAND - MAY 11: Emmanuel Adebayor (2nd right) of Tottenham Hotspur celebrates with team mates after scoring during the Barclays Premier League match between Tottenham Hotspur and Aston Villa at White Hart Lane on May 11, 2014 in London, England.

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5. Manchester City (@MCFC) - 2.18million

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4. Manchester United (@manutd) - 4.03m

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3. Liverpool (@LFC) - 3.64million

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2.Chelsea (@chelseafc) - 4.85million

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1. Arsenal (@Arsenal) - 5million

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"Romania defender Vlad has been complaining of stiffness in his lower back and is continuing to be assessed to determine the extent of the problem, while Sandro is recovering from a virus and has been kept behind on medical advice to avoid the risk of spreading the infection."

Last weekend, it was revealed striker Emmanuel Adebayor needed a short stay in hospital after suffering from malaria.

Tottenham are also set to face Celtic in Helsinki before a final warm-up match against Schalke at White Hart Lane ahead of the new Barclays Premier League season opener at West Ham on August 16.