About Memmert

In over 190 countries all over the world, hundreds of thousands of Memmert products have been permanently in use for decades. This is why Memmert is one of the leading suppliers of temperature control appliances worldwide.

Case Studies

Cell-based assays in the incubator

Prof. Evi Kostenis is the head of a research group at the Institute for Pharmaceutical Biology of the University of Bonn that validated a label-free screening test system for pharmaceutically active substances based on optic biosensors and now uses it for numerous research projects with much success. They use a Peltier-cooled incubator IPP and an incubator I, both by Memmert, to ensure precise temperature control during the assays.

November 2010 temperature distribution in Memmert ovens

11/06/2010
Publications

Under the heading “Safe Processes“, the German laboratory journal GIT published a report by the independent accredited test laboratory, testo industrial services, on the outstanding results of various heat distribution measurements in the Memmert heating oven UFP 500. The requirements of the stricter standard DIN 12880:2007-05 were met with no problem. It turned out that for comparable appliances from competitors, on the other hand, the heating and control technology had a lot of catching up to do. In German (translation see below).

Translation Safe Processes

No direct conclusions about the reliability of the control behaviour while heating up can be drawn from the technical data on temperature stability and homogeneity as provided by the manufacturers of heating ovens and incubators. For this reason, the accredited service provider Testo industrial services was contracted to test the Memmert UFP 500 oven. The oven yielded top results for temperatures of 50 °C, 150 °C and 250 °C and fan speeds from 0 to 100%.

An increasing number of manufacturers of heating ovens and incubators now proudly claim in their data sheets that their appliances are tested in accordance with DIN/ISO 12880, which has been tightened in 2007. In reality, these measurements are one-off events and do not necessarily allow inferences to be made about the controlling action of an appliance over longer periods of time.

In order to reproduce processes at any given time in daily routines, however, reliably constant temperatures and controlling accuracy are imperative. Shortly after the introduction of the new standard, the accredited calibration lab Testo industrial services therefore conducted measurements on the Memmert UFP 500 oven in accordance with the updated 12880:2007-05. These measurements clearly showed that in spite of comparable statements of other manufacturers with respect to temperature distribution and constancy, there were significant temperature deviations while heating up and in a stabilised state over longer periods of time. This indicates that several appliances on the market are in dire need of having their heating and controlling technology optimised.

Tightened requirements of DIN/ISO 12880:2007-05

In 2007, the test requirements of the DIN/ISO 12880:2007-05 for heating ovens and incubators were extended. Instead of the previous nine measuring points, the test standard now requires 27 measuring points for appliances with more than 50 litres chamber volume to determine the homogeneity and constancy of temperatures.

The second main modification of the DIN/ISO 12880:2007-05 is also likely to sort the wheat from the chaff. Until now, performance, meaning fast heating up and cooling down, was the focal point. However, this did not include the time it takes until the temperature has reached a stabilised state, so that it really is controlled reliably. According to the new standard, the times stated for heating up, cooling down and recovery are defined by the point in time when the actual temperature in the centre of the oven or incubator chamber stays permanently within the tolerances defined in the standard.

Stabilising and controlling behaviour

Testo industrial services GmbH is an ideal partner when it comes to temperature distribution measurement. The independent service provider is one of the few companies in Germany accredited for heating ovens and incubators. The Memmert UFP 500 heating oven yielded excellent results with different temperature and fan speed combinations in all measurements. Reaching a constant temperature homogeneity even when the fan is off presents a challenge for all ovens. Since warmer air layers rise, heating and controlling technology must be extremely fine-tuned, so that a permanent heat exchange is guaranteed in the whole chamber even for natural convection. Figure 1 exemplifies an even distribution of heat in the Memmert UFP 500 over 120 minutes. The red curve represents the divergence of the most deviating measured values out of 27 measuring points.

Temperature overshoots really must be avoided in a heating oven or incubator, especially when the load is sensitive. If the fan is activated to enhance heat exchange within the chamber, the heating and controlling technology must interact in such a way that the temperature can only increase or decrease within limited tolerances. Appliances with simple ring heaters are likely to reach their limits here. The example in Figure 2 shows that the Memmert UFP 500, with its large-area heating of the entire chamber and its two separately controlled heating zones, controls the temperature very consistently in its stabilised state over 120 minutes, even for a temperature of 250 °C and at full fan speed. Moreover, the temperature is quite homogeneous even during heating up. The red curve shows the difference between the highest and lowest temperature deviation out of a total of 27 measuring points distributed evenly in the chamber.

With the new standard 12880:2007-05, ovens and incubators with excellent controlling accuracy and temperature stability came out on top. And it proves that developing device-specific heating and cooling technology for high consistency, as Memmert has done for years, yields the best results.