Drug Interactions With Medroxyprogesterone Intramuscular Injection

By Susan Lakey, PharmD, MPH
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If certain drugs are used in combination with medroxyprogesterone intramuscular injection, negative interactions may occur. Some of these reactions, such as with antibiotics or retinoids, can decrease the effectiveness of medroxyprogesterone. Other reactions may cause loss of bone density or other potentially serious side effects. To help minimize any complications, tell your healthcare provider about any other medicines, vitamins, or supplements you are taking.

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