Tag: "precursors" at biology news

...blood cells formed in the bone marrow of mice. The precursors to red blood cells are handy for this because such... last stage of red cell formation, and DNA-damaged precursors generate red blood cells containing an easily detected "micronucleus" consisting of fragments of nuc...

...irm the possibility that self-supporting hair cell precursors exist in or can be derived from the postnatal mammalian cochlea. Currently there are no clinical treatments to repair these hair cells vital to normal hearing. In the United States, 30% of people over the age of 65 have a handicapping hearing l...

...al new player in early events that commit fat cell precursors to becoming full-blown fat, according to a report in the February issue of the journal Cell Metabolism, published by Cell Press. Drugs that block some activities of the enzyme, known as xanthine oxidoreductase (XOR), might therefore offer a novel ant...

...emical consequences of long-lived states? Are they precursors to some of the chemical photoproducts that we know cause damage? That's the Holy Grail in this field -- connecting our growing knowledge of the electronic states of DNA with the photoproducts that damage it," he said. ...

...he researchers could then harvest fetal liver cell precursors for transplant. Ultimately, the scientists found that uniparental cells, regardless of parent of origin, were able to functionally replenish the entire blood-producing system of adult mice. The scientists were able to maintain animals for more...

...t, the altered human cells accumulated cholesterol precursors and died because cholesterol is essential for cell survival. To show that Dap1 directly works with P450s and not through some other biochemical steps, Espenshade’s team tested the ability of human Dap1 protein to bind to four of the 57 known human...

...m is an ideal subject for the study of germ cells, precursors of eggs and sperm in all sexually reproducing species. The planarian Newmark studies, Schmidtea mediterranea, is a tiny creature with a lot of interesting traits. Cut it in two (lengthwise or crosswise) and each piece will regenerate a new planari...

... on the skin. These plaques, or lesions, resembled precursors of cancer. Breeding experiments with the mice indicated that high Srcasm levels counteracted the effects of Fyn. The findings reveal that levels of Fyn and Srcasm work in a kind of see-saw ?when Srcasm production is low, dangerous amounts of Fyn ...

...erizing the mechanisms that generate photoreceptor precursors from stem cells. Swaroop believes the research ha...ve proven to be functional. The photoreceptor precursors were transplanted into three different types of mice with retinal degeneration caused by distinct ge...

...lator -- that regulates the formation somites, the precursors of vertebrae. In their most recent findings, the t...ing the periodicity of the production of vertebral precursors in the embryo," said Dr. Pourquié. "I'm excited about this work because mutation of the genes ...

...cular peptide it will create, because neuropeptide precursors undergo extensive post-translational processing." Some of the neuropeptides the researchers discovered were a result of direct measurements of bee brains using an extremely sensitive mass spectrometer. Some of the genes were found because they rese...

...om neural stem cells, has a reciprocal function in precursors of inhibitory and excitatory neurons: cells with high levels of activated Notch became excitatory neurons, while cells with low levels of Notch became inhibitory. Interestingly, the researchers found that one way Notch combats an inhibitory fate is...

...n three dimensions, to form the tubes that are the precursors to new blood vessels," Bresnick says. "Then we got excited." Further tests showed that NK-B could inhibit angiogenesis in four ways. It prevents the production of vascular endothelial growth factor (VEGF), a key stimulator of blood-vessel formatio...

...ithin host tissues and feeding each other chemical precursors needed to make nutrients. In the future, Eisen says, the bacteria will likely evolve into organelles of the insect, losing their distinction as bacteria altogether. Looking ahead, Eisen is continuing to explore the genomes of other animal-bacterial...

...iza Hall Institute have discovered the different " precursors " that produce DC. In doing so, they have also determined that the practical operations of DC are more specialized than previously believed. Rather than being generalized "police "within the body, it seems that DC are effectively organized as special...

...hritis or some cancers. Using immature blood cell precursors grown in a dish, the research team showed that adding MIF to the cells decreases both the final number and maturity of red blood cells. The researchers believe this effect can lead to anemia. When infected with plasmodium, mice genetically engineer...

... "We show in this work that neural crest stem cell precursors are designated very early in development -- as early as the gastrula stages -- and in an independent fashion from those other tissues," said Martín García-Castro . The researchers grew grafts of cells from "stage 3" chick embryos, before the neura...

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