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Did you know that Saturday kicked off National Infant Immunization Week, which is part of a worldwide observance that shines the spotlight on the importance of vaccination? Most of us think of infant immunization as a tool to protect babies from childhood illnesses like chickenpox and whooping cough. But did you know that one infant immunization protects them from cancer later in life?

Globally, hepatitis B virus (HBV) is one of the top causes of cancer. Every year, it kills more than three-quarters of a million people worldwide. An HBV infection might be defeated by the immune system, but when it’s not, it can become a chronic infection. And chronic infections can lead to serious health outcomes, including cirrhosis and liver cancer. The younger you are, the less likely you’ll be able to fight off an HBV infection — 90 percent of infants infected with HBV will develop chronic infections, and 25 percent of them will go on to die prematurely after developing liver disease. Compare that to 2 to 6 percent of infected adults who will develop chronic infections.

Because infants are so vulnerable to developing chronic infections, vaccinating them against hepatitis B at birth makes sense.

Most people think of hepatitis as a bloodborne disease, and it is spread very efficiently when IV drug users share needles, during needle-stick accidents and other occupational injuries, or by using contaminated piercing needles, tattoo equipment, or acupuncture needles. Even sharing items like razors, toothbrushes, and nail clippers can do it, as the virus can survive outside of the human body for a week. HBV can also be spread by sexual contact, including vaginal and anal sex.

Lastly, babies and children can be at risk as the virus can be transmitted from mother to infant during birth, and during early childhood when risk of chronic infection is high. A significant number of people with chronic infections acquired them during early childhood, but we don’t know exactly how they got them, as their parents and other household contacts were negative for the virus or its antibodies. Since infants and children are at the highest risk for developing chronic infections, focusing on that population for prevention is very important.

Wouldn’t it be great if we could wipe sexually transmitted diseases off the face of the earth? If vaccinologists have a big “to-do” list out there, probably every single infectious disease is on it, including every STD. But some STDs have a higher priority than others, while other pathogens, unfortunately, don’t yield to our efforts quite as easily as other vaccine-preventable diseases.

Celebrate National Immunization Awareness Month by taking a look at a vaccinologist’s hypothetical “to-do” list below. While we already have a couple of STDs checked off that list, there is still more progress to be made!

Human papillomavirus: Gardasil, the most widely used HPV vaccine, introduced a new-and-improved version earlier this year. Gardasil 9 protects against seven strains of HPV that collectively cause 90 percent of cervical cancers and anal cancers, plus the two HPV strains that are jointly responsible for 90 percent of genital warts. Not only that, but vaccination against HPV will also reduce the frequency of “pre-cancers,” which are cellular abnormalities that can be treated before progressing into full-fledged cancer — meaning less time, money, and anxiety spent dealing with follow-up procedures and treatments. In fact, Australia is already seeing a huge nosedive in genital warts and pre-cancers — all thanks to their sky-high HPV vaccination rates.

Hepatitis A and B: Hepatitis, a disease of the liver, can be caused by several types of viruses, including hepatitis A virus and hepatitis B virus. Both can be transmitted sexually, but thanks to the vaccines, you can ask to be protected against them using a combination vaccine, meaning you’ll only have to get three shots over a six-month period rather than the five shots you’d receive if you were vaccinated for the two viruses separately. Continue reading →

One of my least-favorite medical memories must have happened when I was 5 years old, give or take. All I remember is that I was very small, surrounded on all sides by my mom, my pediatrician, and a nurse, and shrinking into a corner as the nurse came at me with a needle. I was squirming and protesting and cringing, but she grabbed my arm and pierced it with a syringe, quick as lightning. Before I could howl in protest, it was over.

Arm yourself against genital warts with Gardasil!

But here’s the thing: It hurt. A lot. And for days afterward, I went about my business feeling as if I had been punched in the arm. When I complained to my mom about how sore I was, she said that my muscles were completely tensed up, and shots hurt more when your muscles are tense. That fact only compounded my annoyance — why had that mean old nurse pricked me at the height of my freakout? If someone had just explained it to me, maybe I could have calmed down enough to relax my muscles and minimize the pain.

That incident made a mark on me, and once I hit adulthood I saw no reason to continue inviting the painful sting of immunization if I didn’t have to. It wasn’t until vaccine-preventable diseases like pertussis and measles started making a comeback that I had to admit to myself that avoiding immunization wasn’t anything to be proud of, and I started getting all my booster shots and yearly influenza vaccinations. Continue reading →

Despite the fact that it’s been approved for males for years, Gardasil is still largely seen as a vaccine for girls, and human papillomavirus (HPV) is still thought of by many as a virus that only impacts the female population. The fact of the matter is that HPV can have serious consequence for boys and men, and Gardasil is an important tool in protecting their sexual health. Why, then, does the association between girls and Gardasil persist?

Let’s stop thinking of Gardasil as the cervical cancer vaccine. Gardasil is a cancer vaccine, period.

Before Gardasil’s introduction, the pharmaceutical company Merck launched an HPV-awareness campaign to get a buzz going for their upcoming vaccine. Their talking points could be boiled down to one simple fact: HPV causes cervical cancer. Outside of the medical field, HPV was a little-known virus, and Merck strove to connect HPV and cervical cancer in the public’s mind so that, after it hit the market, Gardasil’s value would be easily recognized.

So the origins of the association between girls and Gardasil lie in its marketing — and the fact that the Food and Drug Administration (FDA) initially only approved its use in females. From its introduction in 2006 until 2009, Gardasil was only FDA-approved for use in girls and women, and its routine use in males was not recommended by the Advisory Committee on Immunization Practices until December 2011.

While Gardasil’s website is currently gender neutral, archives show that before FDA approval for males, it contained photos of young women and female-specific language. This initial focus on female recipients could have “feminized” Gardasil, entrenching its association with girls and women in the cultural imagination. Some scholars say that, by only recommending it for one sex, the FDA implicitly assigned liability for HPV transmission to females, and advertisers framed the woman as a disease vector in taglines targeting females, such as “spread the word, not the disease.” Although a male’s sexual history is a major predictor of a female partner’s HPV status, girls and women were assigned sole responsibility for their HPV status while boys and men were not similarly burdened. Such messages downplayed the male role in HPV transmission as well as HPV’s effect on males. Continue reading →

One of the most confusing sexually transmitted diseases (STDs) out there is human papillomavirus, or HPV. Despite the fact that it’s the most common STD in the United States, most Americans don’t know very much about it. So, whenever I wade into conversations about HPV on Internet message boards, I prepare myself to enter an ocean of misinformation and misunderstandings.

The strains of HPV that cause genital warts are different from those that cause cancer.

This post, in fact, was inspired by some particularly egregious falsehoods spouted by quite confident-sounding message-board denizens who were dispensing advice to a distraught man with genital warts. He had read that the virus responsible for genital warts was also responsible for cervical cancer, and was upset that he might have “given” cancer to his beloved girlfriend. While some commenters gave good advice, others shared ideas that were not factually correct — and in a forum devoid of sources or citations, it would have been difficult for him to distinguish the bad information from the good.

Situations such as these highlight why it’s not a great idea to get medical advice from the “hive mind” of the World Wide Web. I know American health-care access still isn’t all it can be, but dang — I hope most people know to use reputable sources, like the Centers for Disease Control and Prevention (CDC), whenever they take to the ’net in search of health information.

The first thing to know about HPV is that it can be spread by any type of sexual contact — penetrative and non-penetrative. It can be transmitted by vaginal sex and anal sex, as well as by oral sex or rubbing genitals together, even without penetration. Continue reading →

This is starting to tick me off. Too many parents are not taking advantage of the Gardasil vaccine — which prevents cancer. CANCER. Come on, people. Seriously. (Yahoo Health)

Hopefully people aren’t avoiding vaccinating their children with Gardasil due to “promiscuity” worries. ’Cause that’s been thoroughly debunked! (Slate Double X)

Despite the gross miscarriage of justice that was Burwell v. Hobby Lobby, the Obama Administration is actually kicking butt in the fight for contraception coverage. (Think Progress)

Oh look, Arizona Republicans are trying to pass new and horrible abortion legislation! There’s something you don’t see every day. #Sarcasm (Tucson Weekly)

Could the future of birth control possibly include a pill that would allow men to have “dry” (fluid free) orgasms????? No babies and no fretting over that dastardly “wet spot” on your 800 thread count sheets! Dreams really might come true after all. (The Atlantic)

Ever think about the temperature of the place you store condoms and other birth control? If not, it’s probably a good idea to start! #BetterSafeThanSorry (Bustle)

It’s January, which means it’s time to festoon our surroundings with streamers, throw around the confetti, break out the noisemakers, and shout Happy Cervical Health Awareness Month!

And, in 2015, we have something huge to celebrate: Last month, the Food and Drug Administration (FDA) approved Gardasil 9, the next-generation HPV vaccine, which provides broader protection than the current version. Next month, the new and improved vaccine will start to be shipped to health care providers, and the Advisory Committee on Immunization Practices is expected to give the Centers for Disease Control and Prevention the green light to recommend the vaccine, after which insurance plans and the Vaccines for Children program should start covering it.

The newest version of Gardasil protects against the seven strains of human papillomavirus that together cause 90 percent of cervical cancers.

Why is this news so exciting for people who care about cervical health? Because, while the current version of Gardasil, which debuted in 2006, protects recipients from the two HPV strains that cause 70 percent of cervical cancers, Gardasil 9 will protect against seven strains of HPV that collectively cause 90 percent of cervical cancers. On top of that, both versions of Gardasil protect against the two HPV strains that are together responsible for 90 percent of genital warts.

Gardasil 9 has been shown to be highly effective in clinical studies, and it is safe to use, which means Gardasil just became an even more potent weapon against cancers caused by HPV. Not only that, but vaccination against HPV will also reduce the frequency of precancerous lesions, which are cellular abnormalities that can be treated before progressing into full-fledged cancer. Less pre-cancer means less time, money, and anxiety spent dealing with followup procedures after an abnormal Pap test, for example. Continue reading →