Wild party broken up in Sydney's east

A 19-year-old eastern suburbs woman was sprayed with capsicum spray after allegedly assaulting police as they attempted to arrest her friend at a party, police say.

It was one of a number of violent incidents on what was a typically busy Saturday night for police in Sydney, including shots allegedly being fired in the city's west.

According to police media, the capsicum spray incident occurred when police went to a home on Pacific Avenue, Tamarama about 11.30pm, after receiving complaints from neighbours about excessive noise.

When a 25-year-old woman was arrested at the home over alleged offensive behaviour, the 19-year-old allegedly attempted to intervene and assaulted police. The younger woman was also arrested, and according to police was sprayed with capsicum.

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Later in the night, Blacktown police were called to a house on Hope Street, Seven Hills, following a report that shots had been fired "into the home".

No one was injured and police are urging anyone with information to call Blacktown police or Crime Stoppers.

In another incident, a 19-year-old woman was robbed at knifepoint in Parramatta.

Police say the woman was walking along O'Connell Street about 8.15pm when she was approached by a man near a pedestrian crossing.

The man allegedly threatened her with a knife and demanded her mobile phone, before fleeing towards Fennel Street. Police are still searching for the alleged offender and are asking anyone with pertinent information to come forward.

Meanwhile, there was a serious one-punch attack in the state's central west on Saturday afternoon.

Police say a 16-year-old boy was walking with friends inside a shopping centre in Orange when he was allegedly approached by a 20-year-old man who punched him in the head, causing him to fall to the ground.

The teenager suffered a fractured skull and lost consciousness. He was treated by paramedics and taken to a local hospital, where he remains in a serious but stable condition.