GTX 750 Ti Can Handle any Motherboard on PCIx16 slot...PCIe 3.0 only offers more bandwidth but in real world use like games you won't notice a difference. PCIe 3.0 isn't fully utilized yet so you'll be fine.even a PCIe 3.0 GPU will work in 2.0 with 0 problems...

If you do a system build and add the video and audio card listed above to the build, ensure the compatibility mode is turned on... you can then click on motherboards and it will give you a list of compatible boards you can choose from, along with various prices from different vendors.