Vanity Fair’s fourth New Establishment Summit will focus on art and content in the digital age by bringing together leaders and entrepreneurs in technology, entertainment, finance, and politics. Recently confirmed speakers include directors Patty Jenkins and Ava DuVernay; Disney C.E.O. Bob Iger;Ted Sarandos, Netflix’s chief content officer; and former U.S. secretary of state John Kerry.

Preet Bharara, former U.S. attorney for the southern district of New York, and Sally Yates, former U.S. deputy attorney general, will share the stage for a conversation about challenges to America’s legal culture, and how those challenges could shape society. The summit takes place October 3 and 4 at the Wallis Annenberg Center for the Performing Arts in Beverly Hills, and is presented by Condé Nast.

Los Angeles-based innovators will play a prominent role in the program. Evan Spiegel, co-founder and C.E.O. of Venice, California-based Snap Inc., will be interviewed by Walter Isaacson, author of a forthcoming book on Leonardo da Vinci. The conference will open with a panel discussion on the future of Los Angeles from the perspective of the arts community. The panel will feature Michael Govan, chief executive officer of the Los Angeles County Museum of Art (LACMA), actress and director Anjelica Huston, and architect Sir David Adjaye.

Other sessions include a look at how the 1990s have irrevocably shaped modern political and cultural discourse, and a panel on how technology—and tech companies—will transform the way we watch sports. The conference will conclude with Larry David in conversation with Graydon Carter, editor of Vanity Fair. A complete schedule of panels and interviews may be found on the summit site.

Discovery Communications and BMW are presenting sponsors of the summit. HBO, Dom Pérignon, and Hennessy X.O are principal sponsors. LionTree, Moncler, American Airlines, and The Venetian Las Vegas are supporting sponsors.