Lot's of possible endings for the show. What would be neat is for everybody to take a month or so to think about it, and then offer two things:
1. How would you like the show to end,with specific outcomes for each major character;
2. How do you think it will end, with specific outcomes for each major character.
Maybe the one closest to the actual ending will get a "Walter White AttaBoy"!

I think Hank's wife, Marie, grows increasingly suspicious about Skylar and Hank starting to think about Walter being involved might play into it as well as she will know something is up but Hank will not say anything to her.

So she follows Sklyar one day and sees her dropping something off at the storage room.

Then she has a klepto relaspe and steals it. Well maybe it is not a klepto thing but she steals the money some way and thinks she is doing it to protect Skylar.

This sets off a trigger of events when Skylar finds out the money is gone but does not know where or how...at the same time Walt gets a tip that Hank or the DEA is closing in on him so he goes to get the money and it is gone.

Kind of a flash back to when Skylar took the money to pay off Ted's debts and Walt needing the money.

So Walt takes off. Sklyar moves in with Hank and Marie with the kids as she either acts ignorant of the situation or she pleads to Hank and Marie that she is innocent and only did it because she was afraid Walt would kill her or harm the kids...which would play into her protecting the kids and getting them out of the house thing. Eventually however Skylar winds up going into a mental institution.

Jesse has his money and he wants out so he goes and gets the one girl and they just leave somewhere...maybe mexico or some other country.

Todd winds up taking over the business by being the new best meth cook in the business.

Walt winds up getting surrounded by DEA agents and gets in a massive shoot out because he does not care if he lives or dies because the cancer has returned. However instead they take him alive and he goes to prison and they leave it like he is going to die because of the cancer but never lets you know one way or the other...they could actually have him saying...I beat it once I can do it again or some other thing to leave it up in the air.

With Skylar in a mental institution...Hank and Marie adopt the young child, JR is old enough he would not need adopted. Marie tells Hank about the money. They turn it in but get a substantial reward.

Ok...that was my far out there, no way it would happen, full of holes, 5 minutes of thought scenario.

I think Walt will make his family and their money disappear using "the guy." He then leaves and goes off on his own.

Next, the M-60 is used against Czechs or the kids Uncle and his gang. He tries to get out of the business but they won't let him. He will go back to take care of the problem with the M-60.

Hank will also confront Walt and tell him he knows what's up and that he will catch him. Walt tells him he will turn himself in if his family is left alone.

Right before Walt is ready to turn himself over Jesse visits and tells Walt he knows he poisoned the kid. Pulls out the gun he had when Walt visited him at his house and shoots him in the head killing him. Jesse leaves and gets in his car to drive off with the girl from rehab and her kid. It ends with them driving crossing the Mexican border.

I think Walt will make his family and their money disappear using "the guy." He then leaves and goes off on his own.

Next, the M-60 is used against Czechs or the kids Uncle and his gang. He tries to get out of the business but they won't let him. He will go back to take care of the problem with the M-60.

Hank will also confront Walt and tell him he knows what's up and that he will catch him. Walt tells him he will turn himself in if his family is left alone.

Right before Walt is ready to turn himself over Jesse visits and tells Walt he knows he poisoned the kid. Pulls out the gun he had when Walt visited him at his house and shoots him in the head killing him. Jesse leaves and gets in his car to drive off with the girl from rehab and her kid. It ends with them driving crossing the Mexican border.

THE END

I'm thinking something similar but I think the family gets accidentally killed by the ricin.

Doubt it, time had just passed. He could have told Hank he is out of the business at the point, and really was, when all of a sudden he was approached by some Czechs or gang members. It's all up in the air

Doubt it, time had just passed. He could have told Hank he is out of the business at the point, and really was, when all of a sudden he was approached by some Czechs or gang members. It's all up in the air