Abstract：Abstract : natural gas reservoirs in economic evaluation, mainly USES have internal rate of return, net present value, the investment capital is recovered in technical and economic indexes such as to its development benefit evaluation. However into the development phase, natural gas reservoir exploration and the construction of a productivity has ended, and the related is about the problem of operation cost, operation cost, or will directly affect the economic benefits of natural gas gas reservoir development. Therefore, by using the basic principle of economic technology, combined with the natural gas of gas reservoir development and investment income and expenditure, established the operation of natural gas gas reservoir development economic limit cost model and get the gas gas reservoir development operation cost economic boundary and single well daily output, well depth, the relationship between the price data, finally using these data, applying SPSS software for the data of multiple linear regression, obtained the natural gas gas reservoir development operation cost economic boundary and single well daily output, well depth, the price between mathematical model for gas gas reservoir development operation cost of the calculation of the economic limit provides an easy way.