No history of renal conditions that contraindicate high dosages of sodium

Cardiovascular:

No severe heart disease

No uncontrolled hypertension

No history of congestive heart failure

No history of other cardiovascular conditions that contraindicate high dosages of sodium

Pulmonary:

No severe lung disease

Other:

Not pregnant or nursing

Fertile patients must use effective contraception during and for 4 weeks after study participation

No serious active infections or fever

No other serious concurrent disease

PRIOR CONCURRENT THERAPY:

Biologic therapy:

At least 4 weeks since prior immunotherapy

No concurrent immunomodulating agents

Chemotherapy:

At least 4 weeks since prior chemotherapy (6 weeks for nitrosoureas)

No concurrent antineoplastic agents

Endocrine therapy:

Concurrent corticosteroids for cerebral edema allowed (must be on a stable dose for at least 1 week prior to study entry)

Radiotherapy:

At least 8 weeks since prior radiotherapy

Surgery:

Must recover from prior surgery

Other:

Prior cytodifferentiating agent allowed

No prior antineoplaston therapy

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00003457