The ESC4000 G2S series servers feature vertically-oriented hard disk drive (HDD) bays. This smart arrangement frees up space on either side of the drive bays, allowing more direct airflow from the front panel to the GPUs and other components.

Compared to previous-generation ESC4000 G2 servers, with the fans at full speed the GPUs in G2S servers up to 10% (9°C) cooler; they also require up to 39W less energy and run up to 6.6% (5°C) cooler than previous models.