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Candidiasis is a yeast infection, an inflammatory reaction caused by Candida fungi. Infection occurs when Candida fungi penetrate the tissue, colonize, and release toxins that cause an acute inflammatory response. The infections are also termed moniliasis, which is defined as a yeast infection of the skin and mucous membranes. Infections are common in the mouth (thrush), esophagus, pulmonary system, vagina (moniliasis), and skin (diaper rash). Most typically, Candida infections occur in moist areas of the skin such as skin folds, around fingernails, and in mucous membranes, with the most common site being the vulvovaginal area. Candida may infest wounds, catheter sites, and intravenous sites. Infections may take 6 to 8 weeks to resolve. In immunosuppressed patients, candidiasis can become disseminated by entering the bloodstream and causing serious infections in other organs; such infections are difficult to eradicate. Candida albicans is the most common fungus that causes pathology in patients with the human immunodeficiency virus (HIV), and women with persistent and severe infections should have HIV testing.

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