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Actress Catherine Zeta-Jones is set to play a female drug lord in an upcoming biopic called The Godmother.

Zeta-Jones has been tapped to play Griselda Blanco, the first and only woman to rise to the high ranks of Colombia's Medellin drug cartel.

Blanco became a menacing figure during the drug wars in Miami, Florida in the 1970s and 1980s, and earned the nickname La Madrina (Black Widow). She was suspected to have ordered hundreds of assassinations to keep her money and power.

Norwegian director Eva Sorhaug is set to helm the project, which will begin filming early next year (15).

Zeta-Jones is no stranger to the crime drama genre - she portrayed the wife of a drug kingpin in the hit 2000 film Traffic.