Drug permeability

Permeability across biological membranes is a key factor in the absorption and distribution of drugs. Poor permeability can arise due to a number of structural features, as well as membrane-based efflux mechanisms. This can lead to poor absorption across the gastrointestinal mucosa or poor distribution
throughout the body.

CDCO offers in vitrocell-based methods to simulate gastrointestinal permeability and transporter interactions, and in vivo models to assess brain uptake.