Try using CleanRip to rip them. I'd recommended running then through DiscEx without compressing them, but alternatively you can created the folder yourself and name the game. Example using Zelda Wind Waker

USB:/Games/GZLE01/game.iso

Make sure any games you're trying to run follow that structure, even naming the game as "game.iso"...literally name it game.iso and not after the games name, simply game.iso and nothing more. If your unsure what to name the games folder (ie my GZLE01 folder) look up the specific game on GameTDB and it should tell you what the ID is, just make sure you get the correct ID.

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DiscEX is pretty useless since resizing games to play on the Wii makes them pretty much unplayable, though it does name the folders correctly. USB Loader GX gives the ripped games their respectful folders and names the ripped game; game.iso. Now, I did use my old PNY 2GB flash drive I use for repairing computers and was able to play Luigi's Mansion on it with out a problem, but I formatted it to FAT16 Cluster Size 32KB. My External 320GB Western Digital HDD has the GC games partition as FAT32 32KB Clusters. I wonder if that's what's causing the problems. I'll edit this post later OR make a new one detailing if changing the partition's format works. Cause all my other flash drives formatted to FAT32 don't work either, the only one I formatted to FAT16 ends up working. :U

DiscEX is pretty useless since resizing games to play on the Wii makes them pretty much unplayable, though it does name the folders correctly. USB Loader GX gives the ripped games their respectful folders and names the ripped game; game.iso. Now, I did use my old PNY 2GB flash drive I use for repairing computers and was able to play Luigi's Mansion on it with out a problem, but I formatted it to FAT16 Cluster Size 32KB. My External 320GB Western Digital HDD has the GC games partition as FAT32 32KB Clusters. I wonder if that's what's causing the problems. I'll edit this post later OR make a new one detailing if changing the partition's format works. Cause all my other flash drives formatted to FAT32 don't work either, the only one I formatted to FAT16 ends up working. :U

Ummm, what? How's compressing them make them unplayable? Lol only certain games won't work compressed but most do...trust me, I use compressed/scrubbed GC and Wii games and 99% of them work compressed. Though you are right, games can be played without using DiscEx...it's entirely up to the person if they want to use that program.

Anyway, if your GC games are on a separate partition that's probably the cause. The GC games need to be on the primary active partition, you can have all your Wii and GC ISOs on one partition.

Ummm, what? How's compressing them make them unplayable? Lol only certain games won't work compressed but most do...trust me, I use compressed/scrubbed GC and Wii games and 99% of them work compressed. Though you are right, games can be played without using DiscEx...it's entirely up to the person if they want to use that program.

Anyway, if your GC games are on a separate partition that's probably the cause. The GC games need to be on the primary active partition, you can have all your Wii and GC ISOs on one partition.

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My GC games are on the Primary partition and my Wii Games are on a logical partition formatted to WBFS and they work fine in USB Loader GX and WiiFlow.
I heard that a lot of games using DiscEX failed, so I never used it, I know most games work with it but I don't see any point in using it unless I really needed the space.
But if I was having this problem with EVERY other flash drive I have available at my disposal, then it's not an issue with how many partitions I have because each one of those flash drives don't have partitions. The issue was that FAT32 wasn't working for me and I had to format to FAT16 w/ 32KB Clusters. But FAT16 only works on 2GB and lower, so there's no way to partition a HDD to FAT16. I'll need to see if I can find a way to get games to work from the HDD instead of just the flash drive.

What program do you use to format? I've always had luck with EASUS, if you haven't already you may want to consider trying that.

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I thought that too, but then I have four other flash drives that don't work the same FAT32 32KB Cluster setup.

I've never had issues with Aomei Partition Assistant, I used to use EASEUS, their practically the same, but Aomei has features I like and a better looking UI.

I have two flash drives that work, one using FAT16 @ 32KB Clusters and the other FAT32 with 16KB Clusters, both work flawlessly. One is a PNY the other is a Philips 2GB.
I'm going to change the other primary on my HDD to FAT32 16KB Clusters and see if that does any good. Gonna take a while backing up all the data then copying it back.

Most Portable/External HDD's use Western Digital HDD's because their reliable and heavy duty, I have never had a bad WD drive before, ever, but I have had countless Seagate's and Hitachi Travelstar's go kaput on me, specially Seagate. Though Seagate promised better HDD's so I gave them another chance and currently use a 1TB in my desktop and so far so good. Also, most of the time, the Wii doesn't like the SATA-to-USB or IDE-to-USB bridge controller, doesn't have much to do with the HDD itself.

I've always had good luck with my Seagates, but a couple people I know had WDs and had them die after only owning them a year....but I also know people who have WDs and have no issues at all so who knows. In either case it definitely is strange that your HDD and some other USB devices aren't working right with this using FAT32 32kb clusters, when you said that some are. Wish I could help you out here but I'm not sure what else to say about it, it's oblivious the HDD is having issues with either the program or the Wii itself. Hope you can solve the issue.

My GC games are on the Primary partition and my Wii Games are on a logical partition formatted to WBFS and they work fine in USB Loader GX and WiiFlow.
I heard that a lot of games using DiscEX failed, so I never used it, I know most games work with it but I don't see any point in using it unless I really needed the space.
But if I was having this problem with EVERY other flash drive I have available at my disposal, then it's not an issue with how many partitions I have because each one of those flash drives don't have partitions. The issue was that FAT32 wasn't working for me and I had to format to FAT16 w/ 32KB Clusters. But FAT16 only works on 2GB and lower, so there's no way to partition a HDD to FAT16. I'll need to see if I can find a way to get games to work from the HDD instead of just the flash drive.

Just because your wii games are on a logical partition does not make the fat 1st partition. You have to make all partitions logical and change the fat to primary 1st plus active and then the other partition could primary as long as the fat is the first partition

since I am having problems trying to edit my posts just want to mention that DiscEX never compress any of my GCgames you need GCReEx to compress it and in fact if you compress it with GCReEX, DiscEX says it is under-dumped so I do not compress any of my GC games and I still use DiscEX and all my GCgames works perfect and it does not matter how many partitions you have on the hard drive primary or logical the FAT32 has to be 1st partition for GC games to work
2TB WD, Ist partition FAT32 primary plus active, 2nd partition NTFS primary for the 1st Wii
1.5TB Seagate, one partition FAT32 primary for the 2nd Wii
500GB Toshiba, one partition FAT32 primary for the Wii, Xbox360 or PS3
no issues with all three hard drives all Wii and GC backups and homebrew works perfect, do not even need a SD card

since wad manager1.7 does not let me install wads from USB, I sometimes use wad manager 1.8

Acronis Disk Director 11 Advanced and MiniTool Partition Wizard changes the cluster size without formatting your drive you do not lose your data plus it is very quick, I made a backup of the homebrew stuff and remove it from the drive but I left all the games and movies on the hard drive and I did not lose any and they all work perfect after I change the cluster size from 64KB to 32KB then I put back all the homebrew stuff usually what you keep on the SD back on the drive so I do not need the SD card in the Wii

ugh...problems loading the gc games

So I have the usb loader gx r 1200(iso249) with d2x v8 iso56 and Dios Mios v2.2(iso249)
When i get to usb loader gx i click the game (Im pretty sure I have all the setting right.) and it starts to load.
It gives me the same DML cant use no disk feature or w.e (The same thing SNES got earlier in this thread but I couldnt find it to get the fix.)
And then it goes to black, after a few seconds the Dios Mios screen pops up. Then black again. And i waited a few minutes and nothing came back. (These im trying to play from an hdd btw)

Ive been working at this stuff for the past two days and have become more familiar with everything thats actually going on. Any help would be wonderful.

My isos that I am using I used usb loader gx to rip from the disks to my hdd. I have the compression settings on in the usb loader.
(I only have 4 games, Luigis mansion, windwaker, sm sunshine, and pikman)
Im using a 320gb wd passport. one of the older models.
Ive tried reinstalling both the usb loader and dios mios. Have not tried the cios because im not really sure what it does.

Thanks for any help ive hit a dead end. My final idea is try some other gc isos im going to try that later.