Synopsis: The current study uses a randomized control design to evaluate the benefits of using the DISC, an evidence-based, computerized psychiatric interview in 31 school-based health and mental health clinics in New York City. Findings reveal that structural differences between health and mental health clinics may affect the way the DISC enhances their services. In health clinics, the tool may increase self-referrals, intake assessments, and cases referred for psychiatric medication evaluations and individual therapy. Across clinics with the DISC, clinicians reported an increase in assessment visits with youth as well as the number of re-assessments. Further, the DISC was reported to be helpful because it facilitated clinical diagnosis and communication with youth. Therefore, the results have implications for improving assessment strategies used in these settings.