Bile Acid Sequestering Agents: May interfere with the action of Ursodiol Tablets by reducing its absorption (7.1) Aluminum-based Antacids: May interfere with the action of Ursodiol Tablets by reducing its absorption (7.2) Drugs that alter the metabolism of lipids or induce cholestasis may interfere with the action of Ursodiol Tablets (7.3)