Describe the physiological changes which occur in the GI tract during pregnancy

Describe the haematological changes which occur during pregnancy

-Prothrombotic state with increased fibrin deposition at implatation site and increased fibrinogen and clotting factors in blood.-Reduced fibrinolysis and changes in vascular flow due to venodilation-Anaemia

34

Why cant you give warfarin in thromboembolic disease of pregnancy?

-Warfarin can cross the placenta and is teratogenic

35

What causes anaemia during pregnancy?

-Plasma volume increases more than red cell mass -> physiological anaemia-Can also be due to Fe or folate deficiencies

36

Describe changes in the immune system during pregnancy

-Non-specific suppression of the local immune responses at the materno-fetal interface

37

Give 2 diseases which can occur due to transfer of antibodies across the placenta