1. The biochemical and haematological effects of tolmetin (a pyrole acetic acid derivative), on blood sugar,' serum cholesterol, serum uric acid, blood count, coagulation time, plasma fibrinogen content and euglobin clot lysis time (ELT) were studied in albino rabbits
2. Tolmetin (10 mg/kg), (P.O.) produced marked and significant hypoglycaemic, hypocholesterolaemic and hypouricaemic effects which started after one hour with a peak effect at two hours without complete recovery even upto four hours.
3. It decreased coagulation time and platelet count but increased plasma fibrinogen level and ELT.

1. The biochemical and haematological effects of tolmetin (a pyrole acetic acid derivative), on blood sugar,' serum cholesterol, serum uric acid, blood count, coagulation time, plasma fibrinogen content and euglobin clot lysis time (ELT) were studied in albino rabbits
2. Tolmetin (10 mg/kg), (P.O.) produced marked and significant hypoglycaemic, hypocholesterolaemic and hypouricaemic effects which started after one hour with a peak effect at two hours without complete recovery even upto four hours.
3. It decreased coagulation time and platelet count but increased plasma fibrinogen level and ELT.

1. The biochemical and haematological effects of tolmetin (a pyrole acetic acid derivative), on blood sugar,' serum cholesterol, serum uric acid, blood count, coagulation time, plasma fibrinogen content and euglobin clot lysis time (ELT) were studied in albino rabbits
2. Tolmetin (10 mg/kg), (P.O.) produced marked and significant hypoglycaemic, hypocholesterolaemic and hypouricaemic effects which started after one hour with a peak effect at two hours without complete recovery even upto four hours.
3. It decreased coagulation time and platelet count but increased plasma fibrinogen level and ELT.

Seventeen antihistamines were studied far their effect on acetylcholine (Ach) Induced contraction of skeletal muscle (Skm) under Gaddum's superfusion technique. All drugs exhibit some degree of cuare like action In 0.1 to 10 mcg dose except in pheniramine, mabhydroline and metiamide where there was a regression of curarimimetic effect with increasing doses. During recovery from drug effect the tissue showed an increased sensitivity to the action of Ach. In some instances this potentiation was immediate. In high doses (100 mcg and above). some of the antihistamines produced contracture of Skm which was not blocked by curare.

1. The biochemical and haematological effects of tolmetin (a pyrole acetic acid derivative), on blood sugar,' serum cholesterol, serum uric acid, blood count, coagulation time, plasma fibrinogen content and euglobin clot lysis time (ELT) were studied in albino rabbits
2. Tolmetin (10 mg/kg), (P.O.) produced marked and significant hypoglycaemic, hypocholesterolaemic and hypouricaemic effects which started after one hour with a peak effect at two hours without complete recovery even upto four hours.
3. It decreased coagulation time and platelet count but increased plasma fibrinogen level and ELT.

1. The biochemical and haematological effects of tolmetin (a pyrole acetic acid derivative), on blood sugar,' serum cholesterol, serum uric acid, blood count, coagulation time, plasma fibrinogen content and euglobin clot lysis time (ELT) were studied in albino rabbits
2. Tolmetin (10 mg/kg), (P.O.) produced marked and significant hypoglycaemic, hypocholesterolaemic and hypouricaemic effects which started after one hour with a peak effect at two hours without complete recovery even upto four hours.
3. It decreased coagulation time and platelet count but increased plasma fibrinogen level and ELT.

1. The biochemical and haematological effects of tolmetin (a pyrole acetic acid derivative), on blood sugar,' serum cholesterol, serum uric acid, blood count, coagulation time, plasma fibrinogen content and euglobin clot lysis time (ELT) were studied in albino rabbits
2. Tolmetin (10 mg/kg), (P.O.) produced marked and significant hypoglycaemic, hypocholesterolaemic and hypouricaemic effects which started after one hour with a peak effect at two hours without complete recovery even upto four hours.
3. It decreased coagulation time and platelet count but increased plasma fibrinogen level and ELT.