I've only started taking Zoloft for 4 days, and I can't sleep, and I am anxious all the time, not even in social situations! I thought Zoloft takes several weeks to start working...I'm pretty sure it is the Zoloft because nothing else in my daily life has changed. Is it normal to experience these side effects so early? My doctor told me to report back to him in 3 weeks. Should I keep taking the Zoloft to see if things improve?

Side effects of antidepressants kick in instantly, but it takes weeks until they (fully) work. It will very likely get better, so I suggest you take it as prescribed. Pdocs can give low-medium dose benzos for ~2 weeks to combat increased anxiety and insomnia.

melissa's tip is good: Take it in the morning when you get insomnia from it.

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