[excerpts] ... HHS's plan has two specific goals that relate to vaccines. The first goal is to have in place by 2011 domestic production capacity sufficient to supply vaccine to the entire U.S. population within six months of the onset of a pandemic. The second goal is to stockpile enough doses of vaccine to inoculate 20 million people as soon as possible after the onset of a pandemic. ... This Congressional Budget Office (CBO) paper, which was prepared at the request of the Senate Majority Leader, focuses on the government's role in the vaccine market that stems from HHS's plan. It provides information on the current state of readiness, the additional expenditures likely to be necessary to achieve HHS's vaccine-related goals, the expenditures that are likely to be needed to maintain preparedness, and the approaches of other countries as they too face the prospect of an influenza pandemic.

Contents

Summary ix 1 The Market for Seasonal-Influenza Vaccine and the Challenge of Providing Vaccine in a Pandemic 1 The Market for Seasonal-Influenza Vaccine 3 Supplying Vaccine in a Pandemic 5 Overview of HHS's Plan 5 Risks Associated with HHS's Plan 7 Additional Public Health Questions 7

Figures1-1. Vaccine Production for the 2006­2007 Influenza Season in the United States 4 1-2. Seasonal-Influenza Vaccine for the U.S. Market 4

Boxes2-1. Vaccine Development: Typical Time and Cost 10 2-2. What Constitutes the Next Generation of Influenza Vaccines? 16______________________________ This information is provided to subscribers, friends, faculty, students and alumni of the School of Industrial & Labor Relations (ILR). It is a service of the Institute for Workplace Studies (IWS) in New York City. Stuart Basefsky is responsible for the selection of the contents which is intended to keep researchers, companies, workers, and governments aware of the latest information related to ILR disciplines as it becomes available for the purposes of research, understanding and debate. The content does not reflect the opinions or positions of Cornell University, the School of Industrial & Labor Relations, or that of Mr. Basefsky and should not be construed as such. The service is unique in that it provides the original source documentation, via links, behind the news and research of the day. Use of the information provided is unrestricted. However, it is requested that users acknowledge that the information was found via the IWS Documented News Service.