Meg Ryan arrives at the 2005 Vanity Fair Oscar Party at Mortons in West Hollywood February 27, 2005. (Reuters/ Kimberly White)

Actress Meg Ryan arrives for Puccini's "Madama Butterfly" at Lincoln Center Plaza in New York September 25, 2006. (Reuters/Shannon Stapleton)

Actress Meg Ryan, who stars in the motion picture crime thriller "In the Cut," poses as she arrives during the premiere of the film at the Academy of Motion Picture Arts & Sciences in Beverly Hills, California October 16, 2003. (Reuters/Jim Ruymen)

Actress Meg Ryan speaks during "Earth to L.A. The Greatest Show on Earth" a benefit for the Natural Resources Defense Council, an environmental group working to safeguard the environment through education and legislation, in Los Angeles May 6, 2004. (Reuters/Fred Prouser)