I tried the send to Speed Grade menu option in Premiere Pro and a progress bar came up, but then did nothing, and Speed Grade did not open. Premiere Pro created a file for Speed Grade, (has the Speed Grade icon) but clicking on the file also does nothing.

Ok - Issue is resolved. Adobe logged into my machine but didn't have any luck figuring it out. They did determine that SpeedGrade would work in another User Account which made them think that it was a permissions problem. They suggested that I contact Apple for information on how to REALLY repair permissions, which they did. Still no luck. Back to Adobe they said.

Thinking about what Dennis said about that SpeedGrade preferences were in the Documents folder, not the hidden library folder, I first manually deleted the SpeedGrade preferences folder that was in the Adobe folder in the Documents folder, restarted, emptied the trash. Then I simply copied the files that were in the Adobe folder in the Documents folder of the user account where SpeedGrade worked to the Adobe folder in the Documents folder of the problem user account.

I tried this same mode of attack with no luck. My speedgrade however will launch on another user. When I went in on my main account to disable root user, I found that I was never even enabled in the first place, so that didn't do me any good. is this an apple issue or adobe?