Effects of a Probiotic on Body Weight

Summary

Probiotics administration is associated with health benefits on gut barrier integrity and
immunological functions of the gastrointestinal tract. Recently, probiotics consumption was
proposed to reduce fat mass and body weight in rodents (Lee HY. et al. 2006; Hamad EM. et
al. 2009) as well as abdominal fat in human (Kadooka Y, 2010). The mechanisms explaining
the effects of probiotics in weight control are not well understood.

The primary objective of the clinical trial is to investigate whether a consumption of a
probiotic formula when compared to an intake of a placebo, is associated with a greater
reduction of body weight.

The effect of probiotic supplements among subjects undergoing bariatric surgery indicates conflicting results. Moreover, whether these effects remain after ceasing the treatment remained to be elucida...

The aim of this study was to investigate the effect of synbiotic and probiotic supplementation on serum vascular dysfunction and necrosis markers in hemodialysis (HD) patients. In this randomized, dou...

Perturbations in the gastrointestinal microbiome caused by antibiotics are a major risk factor for Clostridium difficile infection (CDI). Probiotics are often recommended to mitigate CDI symptoms; how...

Childhood obesity is a major public health concern with limited treatment options.

Medical and Biotech [MESH] Definitions

Obesity, Abdominal

A condition of having excess fat in the abdomen. Abdominal obesity is typically defined as waist circumferences of 40 inches or more in men and 35 inches or more in women. Abdominal obesity raises the risk of developing disorders, such as diabetes, hypertension and METABOLIC SYNDROME X.

Obesity, Morbid

The condition of weighing two, three, or more times the ideal weight, so called because it is associated with many serious and life-threatening disorders. In the BODY MASS INDEX, morbid obesity is defined as having a BMI greater than 40.0 kg/m2.

Therapeutic Misconception

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.

Obesity, Metabolically Benign

A sub-PHENOTYPE of obese individuals who have a risk for CARDIOVASCULAR DISEASES between that of healthy individuals with normal weight and unhealthy individuals with obesity.

Pediatric Obesity

BODY MASS INDEX in children (ages 2-12) and in adolescents (ages 13-18) that is grossly above the recommended cut-off for a specific age and sex. For infants less than 2 years of age, obesity is determined based on standard weight-for-length percentile measures.

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