The quest for enlightenment has occupied mankind for millennia. And from the depictions we've seen-monks sitting on meditation cushions, nuns kneeling in prayer, shamans communing with the universe-it seems that this elusive state is reserved for a chosen few. But now, neuroscientist David Perlmutter and medical anthropologist and shaman Alberto Villoldo have come together to explore the commonalities between their specialties with the aim of making enlightenment possible for anyone.