Glyphosate’s Suppression of Cytochrome P450 Enzymes and Amino Acid Biosynthesis by the Gut Microbiome: Pathways to Modern Diseases by Anthony Samsel and Stephanie Seneff

Study Links Monsanto’s Roundup to Autism, Parkinson’s and Alzheimer’s A new review of hundreds of scientific studies surrounding glyphosate—the major component of Monsanto’s Roundup herbicide—sheds light on its effects within the human body. The paper describes how all of these effects could work together, and with other variables, trigger health problems in humans, including debilitating diseases like gastrointestinal disorders, diabetes, heart disease, obesity, Parkinson’s and Alzheimer’s disease.( abridged from news article by GENNA REED ECOWATCH / NEWS ANALYSIS http://www.nationofchange.org/study-links-monsanto-s-roundup-autism-parkinson-s-and-alzheimer-s-1367764115

In this paper (see link below to entire study) Glyphosate’s Suppression of Cytochrome P450 Enzymes and Amino Acid Biosynthesis by the Gut Microbiome: Pathways to Modern Diseases by Anthony Samsel and Stephanie Seneff Published: 18 April 2013 in Special Issue Biosemiotic Entropy: Disorder, Disease, and Mortality , the authors call for more independent research to validate their findings, stating that “glyphosate is likely to be pervasive in our food supply, and contrary to being essentially nontoxic, it may in fact be the most biologically disruptive chemical in our environment.” If the body of independent research on GE foods and the herbicides used with them shows one thing, it is that there are unanswered questions begging for unbiased research. And while these questions remain unanswered, Americans have the right to know how their food was produced.

Glyphosate, the active ingredient in Roundup®, is the most popular herbicide used worldwide. The industry asserts it is minimally toxic to humans, but here we argue otherwise. Residues are found in the main foods of the Western diet, comprised primarily of sugar, corn, soy and wheat. Glyphosate’s inhibition of cytochrome P450 (CYP) enzymes is an overlooked component of its toxicity to mammals. CYP enzymes play crucial roles in biology, one of which is to detoxify xenobiotics. Thus, glyphosate enhances the damaging effects of other food borne chemical residues and environmental toxins. Negative impact on the body is insidious and manifests slowly over time as inflammation damages cellular systems throughout the body. Here, we show how interference with CYP enzymes acts synergistically with disruption of the biosynthesis of aromatic amino acids by gut bacteria, as well as impairment in serum sulfate transport. Consequences are most of the diseases and conditions associated with a Western diet, which include gastrointestinal disorders, obesity, diabetes, heart disease, depression, autism, infertility, cancer and Alzheimer’s disease. We explain the documented effects of glyphosate and its ability to induce disease, and we show that glyphosate is the “textbook example” of exogenous semiotic entropy: the disruption of homeostasis by environmental toxins, http://www.mdpi.com/1099-4300/15/4/1416 Glyphosate’s Suppression of Cytochrome P450 Enzymes and Amino Acid Biosynthesis by the Gut Microbiome: Pathways to Modern Diseases by Anthony Samsel and Stephanie Seneff Published: 18 April 2013 in Special Issue Biosemiotic Entropy: Disorder, Disease, and Mortality