]]>A few reminiscences on Hilary Koprowskihttp://www.microbeworld.org/component/jlibrary/?view=article&id=10466
http://www.microbeworld.org/component/jlibrary/?view=article&id=10466The science-themed art of Deb Skluthttp://www.microbeworld.org/component/jlibrary/?view=article&id=10448
http://www.microbeworld.org/component/jlibrary/?view=article&id=10448Avian influenza H7N7 virus outbreak: Lessons for H7N9http://www.microbeworld.org/component/jlibrary/?view=article&id=10426
http://www.microbeworld.org/component/jlibrary/?view=article&id=10426Hilary Koprowski, Columbia University Medical Center, 2005http://www.microbeworld.org/component/jlibrary/?view=article&id=10424
http://www.microbeworld.org/component/jlibrary/?view=article&id=10424Avian influenza H7N9 viruses isolated from humans: What do the gene sequences mean?http://www.microbeworld.org/component/jlibrary/?view=article&id=10408
http://www.microbeworld.org/component/jlibrary/?view=article&id=10408Henrietta Lacks (HeLa) genome sequence published then withdrawnhttp://www.microbeworld.org/component/jlibrary/?view=article&id=10289
http://www.microbeworld.org/component/jlibrary/?view=article&id=10289Circovirus in Shanghaihttp://www.microbeworld.org/component/jlibrary/?view=article&id=10261
http://www.microbeworld.org/component/jlibrary/?view=article&id=10261Receptor for new coronavirus-EMC identifiedhttp://www.microbeworld.org/component/jlibrary/?view=article&id=10224
http://www.microbeworld.org/component/jlibrary/?view=article&id=10224How I record my lectureshttp://www.microbeworld.org/component/jlibrary/?view=article&id=10162
http://www.microbeworld.org/component/jlibrary/?view=article&id=10162Proposed US policy on dual use research of concernhttp://www.microbeworld.org/component/jlibrary/?view=article&id=10151
http://www.microbeworld.org/component/jlibrary/?view=article&id=10151Antimicrobial peptides induced by herpesvirus enhance HIV-1 infectionhttp://www.microbeworld.org/component/jlibrary/?view=article&id=10138
http://www.microbeworld.org/component/jlibrary/?view=article&id=10138Harvard University: Great virology, bad science writinghttp://www.microbeworld.org/component/jlibrary/?view=article&id=10126
http://www.microbeworld.org/component/jlibrary/?view=article&id=10126Virologia en Españolhttp://www.microbeworld.org/component/jlibrary/?view=article&id=10106
http://www.microbeworld.org/component/jlibrary/?view=article&id=10106Did hepatitis C virus originate in horses?http://www.microbeworld.org/component/jlibrary/?view=article&id=10089
http://www.microbeworld.org/component/jlibrary/?view=article&id=10089Human infections with influenza H5N1 virus: How many?http://www.microbeworld.org/component/jlibrary/?view=article&id=10062
http://www.microbeworld.org/component/jlibrary/?view=article&id=1006250% case fatality rate established by WHO is high, but the lethality of the virus might be lower if there are many infections accompanied by mild or no disease. One way to answer this question is to determine how many individuals carry antibodies to the virus in populations that are at risk for infection. A number of such studies have been done, and some have concluded that the results imply a low but substantial level of infection (even less than one percent of millions of people is a lot of infections). The conclusion of a new meta-analysis of H5N1 serosurveys is that most of the studies are flawed, and that the frequency of H5 infections appears to be low.]]>A virology course for allhttp://www.microbeworld.org/component/jlibrary/?view=article&id=10036
http://www.microbeworld.org/component/jlibrary/?view=article&id=10036The risks and benefits of influenza H5N1 researchhttp://www.microbeworld.org/component/jlibrary/?view=article&id=10019
http://www.microbeworld.org/component/jlibrary/?view=article&id=10019End of moratorium on influenza H5N1 researchhttp://www.microbeworld.org/component/jlibrary/?view=article&id=9992
http://www.microbeworld.org/component/jlibrary/?view=article&id=9992Viruses on Timehttp://www.microbeworld.org/component/jlibrary/?view=article&id=9978
http://www.microbeworld.org/component/jlibrary/?view=article&id=9978Effectiveness of this season’s influenza vaccinehttp://www.microbeworld.org/component/jlibrary/?view=article&id=9959
http://www.microbeworld.org/component/jlibrary/?view=article&id=9959Be curioushttp://www.microbeworld.org/component/jlibrary/?view=article&id=9952
http://www.microbeworld.org/component/jlibrary/?view=article&id=9952Poliovirus on Timehttp://www.microbeworld.org/component/jlibrary/?view=article&id=9926
http://www.microbeworld.org/component/jlibrary/?view=article&id=9926Friday flu shothttp://www.microbeworld.org/component/jlibrary/?view=article&id=9925
http://www.microbeworld.org/component/jlibrary/?view=article&id=9925Deans write to Obama about CIA vaccine scheme in Pakistanhttp://www.microbeworld.org/component/jlibrary/?view=article&id=9912
http://www.microbeworld.org/component/jlibrary/?view=article&id=9912WHO will switch to type 2 inactivated poliovirus vaccinehttp://www.microbeworld.org/component/jlibrary/?view=article&id=9911
http://www.microbeworld.org/component/jlibrary/?view=article&id=9911The gender bias of science facultyhttp://www.microbeworld.org/component/jlibrary/?view=article&id=9905
http://www.microbeworld.org/component/jlibrary/?view=article&id=9905Vaccine-associated poliomyelitis in Pakistanhttp://www.microbeworld.org/component/jlibrary/?view=article&id=9854
http://www.microbeworld.org/component/jlibrary/?view=article&id=9854HIV among US youthhttp://www.microbeworld.org/component/jlibrary/?view=article&id=9851
http://www.microbeworld.org/component/jlibrary/?view=article&id=9851Polio immunizers murdered by Talibanhttp://www.microbeworld.org/component/jlibrary/?view=article&id=9850
http://www.microbeworld.org/component/jlibrary/?view=article&id=9850NIH head defends new center for translational sciencehttp://www.microbeworld.org/component/jlibrary/?view=article&id=9849
http://www.microbeworld.org/component/jlibrary/?view=article&id=9849Glass microbeshttp://www.microbeworld.org/component/jlibrary/?view=article&id=9801
http://www.microbeworld.org/component/jlibrary/?view=article&id=9801Influenza is on the risehttp://www.microbeworld.org/component/jlibrary/?view=article&id=9788
http://www.microbeworld.org/component/jlibrary/?view=article&id=9788Great ape protection acthttp://www.microbeworld.org/component/jlibrary/?view=article&id=9780
http://www.microbeworld.org/component/jlibrary/?view=article&id=9780Virology Lecture: Picornaviruseshttp://www.microbeworld.org/component/jlibrary/?view=article&id=9749
http://www.microbeworld.org/component/jlibrary/?view=article&id=9749Viruses of protozoan parasites may exacerbate human diseasehttp://www.microbeworld.org/component/jlibrary/?view=article&id=9719
http://www.microbeworld.org/component/jlibrary/?view=article&id=9719Spread of koala retrovirus in Australiahttp://www.microbeworld.org/component/jlibrary/?view=article&id=9647
http://www.microbeworld.org/component/jlibrary/?view=article&id=9647World Polio Dayhttp://www.microbeworld.org/component/jlibrary/?view=article&id=9563
http://www.microbeworld.org/component/jlibrary/?view=article&id=9563An RNA virus that infects Archaea?http://www.microbeworld.org/component/jlibrary/?view=article&id=9526
http://www.microbeworld.org/component/jlibrary/?view=article&id=9526Museum pelts help date the koala retrovirushttp://www.microbeworld.org/component/jlibrary/?view=article&id=9493
http://www.microbeworld.org/component/jlibrary/?view=article&id=9493No further evidence of novel coronavirushttp://www.microbeworld.org/component/jlibrary/?view=article&id=9490
http://www.microbeworld.org/component/jlibrary/?view=article&id=9490Behind the scenes: TWiV 202 at the University of Nebraskahttp://www.microbeworld.org/component/jlibrary/?view=article&id=9486
http://www.microbeworld.org/component/jlibrary/?view=article&id=9486A new rhabdovirus from a patient with hemorrhagic feverhttp://www.microbeworld.org/component/jlibrary/?view=article&id=9452
http://www.microbeworld.org/component/jlibrary/?view=article&id=9452A new coronavirus isolated from humanshttp://www.microbeworld.org/component/jlibrary/?view=article&id=9420
http://www.microbeworld.org/component/jlibrary/?view=article&id=9420Behind the scenes: TWiV 200 at the NEIDLhttp://www.microbeworld.org/component/jlibrary/?view=article&id=9408
http://www.microbeworld.org/component/jlibrary/?view=article&id=9408Thirty years in my laboratory at Columbia Universityhttp://www.microbeworld.org/component/jlibrary/?view=article&id=9407
http://www.microbeworld.org/component/jlibrary/?view=article&id=9407The Hershey-Chase food blenderhttp://www.microbeworld.org/component/jlibrary/?view=article&id=9358
http://www.microbeworld.org/component/jlibrary/?view=article&id=9358Behind the scenes: Recording TWIM 40 at Cold Spring Harbor Laboratoryhttp://www.microbeworld.org/component/jlibrary/?view=article&id=9344
http://www.microbeworld.org/component/jlibrary/?view=article&id=9344Here are photographs I took during our visit to Cold Spring Harbor Laboratory to record This Week in Microbiology #40. We roamed around campus scouting locations before deciding on the Szybalski Reading Room in the Carnegie Library. That's Ray Ortega setting up in the Szybalski Reading Room. Also in some photos are Stan Maloy, John Kirby, and Waclaw Szybalski. The Milestones in Microbiology photo includes Stan Maloy, Bruce Stillman, Waclaw Szybalski, and James D. Watson.]]>From a food blender to real-time fluorescent imaginghttp://www.microbeworld.org/component/jlibrary/?view=article&id=9343
http://www.microbeworld.org/component/jlibrary/?view=article&id=9343Video: Cloning HeLa cells with Professor Philip I. Marcushttp://www.microbeworld.org/component/jlibrary/?view=article&id=9311
http://www.microbeworld.org/component/jlibrary/?view=article&id=9311Milestones in Microbiology at Cold Spring Harbor Laboratoryhttp://www.microbeworld.org/component/jlibrary/?view=article&id=9307
http://www.microbeworld.org/component/jlibrary/?view=article&id=9307How lethal is rabies virus?http://www.microbeworld.org/component/jlibrary/?view=article&id=9264
http://www.microbeworld.org/component/jlibrary/?view=article&id=9264A viral mashup in snakeshttp://www.microbeworld.org/component/jlibrary/?view=article&id=9232
http://www.microbeworld.org/component/jlibrary/?view=article&id=9232Is it Ebolavirus or Ebola virus?http://www.microbeworld.org/component/jlibrary/?view=article&id=9203
http://www.microbeworld.org/component/jlibrary/?view=article&id=9203Don’t Panic—Ebola Isn’t Heading For Youhttp://www.microbeworld.org/component/jlibrary/?view=article&id=9190
http://www.microbeworld.org/component/jlibrary/?view=article&id=9190Herpetic Legion - Reactivationhttp://www.microbeworld.org/component/jlibrary/?view=article&id=9156
http://www.microbeworld.org/component/jlibrary/?view=article&id=9156Origin of the H5N1 stormhttp://www.microbeworld.org/component/jlibrary/?view=article&id=9067
http://www.microbeworld.org/component/jlibrary/?view=article&id=9067Influenza H5N1 virus versus ferrets, round twohttp://www.microbeworld.org/component/jlibrary/?view=article&id=8965
http://www.microbeworld.org/component/jlibrary/?view=article&id=8965Aaron J. Shatkin, 77http://www.microbeworld.org/component/jlibrary/?view=article&id=8920
http://www.microbeworld.org/component/jlibrary/?view=article&id=8920Can India remain polio-free?http://www.microbeworld.org/component/jlibrary/?view=article&id=8905
http://www.microbeworld.org/component/jlibrary/?view=article&id=8905Kawaoka paper published on aerosol transmission of H5 influenza virus in ferretshttp://www.microbeworld.org/component/jlibrary/?view=article&id=8730
http://www.microbeworld.org/component/jlibrary/?view=article&id=8730Earth’s virology professorhttp://www.microbeworld.org/component/jlibrary/?view=article&id=8722
http://www.microbeworld.org/component/jlibrary/?view=article&id=8722A mad cow in Americahttp://www.microbeworld.org/component/jlibrary/?view=article&id=8707
http://www.microbeworld.org/component/jlibrary/?view=article&id=8707Capturing viruses with bacteriahttp://www.microbeworld.org/component/jlibrary/?view=article&id=8673
http://www.microbeworld.org/component/jlibrary/?view=article&id=8673More evidence for mild influenza H5N1 infectionshttp://www.microbeworld.org/component/jlibrary/?view=article&id=8638
http://www.microbeworld.org/component/jlibrary/?view=article&id=863850%, which is based on the number of deaths among the fewer than 600 cases confirmed by the World Health Organization. Such fear is misguided, because it is likely that the fatality ratio is far lower. For example, studies of >7,000 healthy individuals have revealed that about 0.5% of them carry antibodies to the virus in their blood, indicating that mild or asymptomatic infections do occur. T-lymphocytes that recognize influenza H5N1 virus have now been detected in a high-risk cohort of individuals in Vietnam, providing additional evidence for asymptomatic human infections.
]]>Building the perfect bughttp://www.microbeworld.org/component/jlibrary/?view=article&id=8587
http://www.microbeworld.org/component/jlibrary/?view=article&id=8587A spike for piercing the cell membranehttp://www.microbeworld.org/component/jlibrary/?view=article&id=8517
http://www.microbeworld.org/component/jlibrary/?view=article&id=8517Tulips broken by viruseshttp://www.microbeworld.org/component/jlibrary/?view=article&id=8478
http://www.microbeworld.org/component/jlibrary/?view=article&id=8478Influenza H5N1 is not lethal in ferrets after airborne transmissionhttp://www.microbeworld.org/component/jlibrary/?view=article&id=8423
http://www.microbeworld.org/component/jlibrary/?view=article&id=8423Renato Dulbecco, 1914-2012http://www.microbeworld.org/component/jlibrary/?view=article&id=8389
http://www.microbeworld.org/component/jlibrary/?view=article&id=8389Evidence for influenza H5N1 infections in humanshttp://www.microbeworld.org/component/jlibrary/?view=article&id=8387
http://www.microbeworld.org/component/jlibrary/?view=article&id=838750%, based on the number of deaths among the fewer than 600 cases confirmed by the World Health Organization. Wang, Parides, and Palese suggest that this number is an overestimate.]]>Norton Zinder, 1928-2012http://www.microbeworld.org/component/jlibrary/?view=article&id=8337
http://www.microbeworld.org/component/jlibrary/?view=article&id=8337H5N1 facts, not fearhttp://www.microbeworld.org/component/jlibrary/?view=article&id=8205
http://www.microbeworld.org/component/jlibrary/?view=article&id=8205Prominent Virologists Want U.S. Advisory Board to Take a Second Look at Controversial Flu Papershttp://www.microbeworld.org/component/jlibrary/?view=article&id=8189
http://www.microbeworld.org/component/jlibrary/?view=article&id=8189My virology course at Columbia Universityhttp://www.microbeworld.org/component/jlibrary/?view=article&id=8176
http://www.microbeworld.org/component/jlibrary/?view=article&id=8176Small fragments of viral nucleic acid cross borders in monkey meathttp://www.microbeworld.org/component/jlibrary/?view=article&id=8141
http://www.microbeworld.org/component/jlibrary/?view=article&id=8141India polio-free for one yearhttp://www.microbeworld.org/component/jlibrary/?view=article&id=8123
http://www.microbeworld.org/component/jlibrary/?view=article&id=8123Palese: Don’t censor live-saving sciencehttp://www.microbeworld.org/component/jlibrary/?view=article&id=8098
http://www.microbeworld.org/component/jlibrary/?view=article&id=8098An engineered doomsdayhttp://www.microbeworld.org/component/jlibrary/?view=article&id=8075
http://www.microbeworld.org/component/jlibrary/?view=article&id=8075Should we fear avian H5N1 influenza?http://www.microbeworld.org/component/jlibrary/?view=article&id=8050
http://www.microbeworld.org/component/jlibrary/?view=article&id=8050Authors retract paper on detection of murine leukemia virus-releated sequences in CFS patientshttp://www.microbeworld.org/component/jlibrary/?view=article&id=8021
http://www.microbeworld.org/component/jlibrary/?view=article&id=8021A bad day for sciencehttp://www.microbeworld.org/component/jlibrary/?view=article&id=8008
http://www.microbeworld.org/component/jlibrary/?view=article&id=8008Megavirus, the biggest known virushttp://www.microbeworld.org/component/jlibrary/?view=article&id=7983
http://www.microbeworld.org/component/jlibrary/?view=article&id=7983Genome of arsenic bacterium sequencedhttp://www.microbeworld.org/component/jlibrary/?view=article&id=7934
http://www.microbeworld.org/component/jlibrary/?view=article&id=7934Ferreting out influenza H5N1http://www.microbeworld.org/component/jlibrary/?view=article&id=7933
http://www.microbeworld.org/component/jlibrary/?view=article&id=7933The dwindling American science majorshttp://www.microbeworld.org/component/jlibrary/?view=article&id=7902
http://www.microbeworld.org/component/jlibrary/?view=article&id=7902Chronic Fatigue Syndrome and the CDC: A Long, Tangled Talehttp://www.microbeworld.org/component/jlibrary/?view=article&id=7864
http://www.microbeworld.org/component/jlibrary/?view=article&id=7864How good is the influenza vaccine?http://www.microbeworld.org/component/jlibrary/?view=article&id=7761
http://www.microbeworld.org/component/jlibrary/?view=article&id=7761Ten seminal virologistshttp://www.microbeworld.org/component/jlibrary/?view=article&id=7729
http://www.microbeworld.org/component/jlibrary/?view=article&id=7729The World of Viruseshttp://www.microbeworld.org/component/jlibrary/?view=article&id=7711
http://www.microbeworld.org/component/jlibrary/?view=article&id=7711

]]>The Lazarus virushttp://www.microbeworld.org/component/jlibrary/?view=article&id=7621
http://www.microbeworld.org/component/jlibrary/?view=article&id=7621David and Goliath: How one cytokine may take down influenzahttp://www.microbeworld.org/component/jlibrary/?view=article&id=7582
http://www.microbeworld.org/component/jlibrary/?view=article&id=7582Scientist Who Led XMRV Research Team Let Gohttp://www.microbeworld.org/component/jlibrary/?view=article&id=7557
http://www.microbeworld.org/component/jlibrary/?view=article&id=7557Robert A. Weisberg, 1937-2011http://www.microbeworld.org/component/jlibrary/?view=article&id=7551
http://www.microbeworld.org/component/jlibrary/?view=article&id=7551Trust science, not scientistshttp://www.microbeworld.org/component/jlibrary/?view=article&id=7523
http://www.microbeworld.org/component/jlibrary/?view=article&id=7523Viral dessertshttp://www.microbeworld.org/component/jlibrary/?view=article&id=7464
http://www.microbeworld.org/component/jlibrary/?view=article&id=7464Gut microbes influence defense against influenzahttp://www.microbeworld.org/component/jlibrary/?view=article&id=7416
http://www.microbeworld.org/component/jlibrary/?view=article&id=7416Wild poliovirus in Chinahttp://www.microbeworld.org/component/jlibrary/?view=article&id=7415
http://www.microbeworld.org/component/jlibrary/?view=article&id=7415Virology at the Deutsches Museumhttp://www.microbeworld.org/component/jlibrary/?view=article&id=7324
http://www.microbeworld.org/component/jlibrary/?view=article&id=7324Dr. Kiki's Science Hour Guest Vincent Racaniellohttp://www.microbeworld.org/component/jlibrary/?view=article&id=7134
http://www.microbeworld.org/component/jlibrary/?view=article&id=7134Live tweeting of the ASV meetinghttp://www.microbeworld.org/component/jlibrary/?view=article&id=7119
http://www.microbeworld.org/component/jlibrary/?view=article&id=7119Transgenic mice susceptible to poliovirushttp://www.microbeworld.org/component/jlibrary/?view=article&id=7013
http://www.microbeworld.org/component/jlibrary/?view=article&id=7013Happy as a clam? Maybe not.http://www.microbeworld.org/component/jlibrary/?view=article&id=6985
http://www.microbeworld.org/component/jlibrary/?view=article&id=6985Poliomyelitis after a twelve year incubation periodhttp://www.microbeworld.org/component/jlibrary/?view=article&id=6935
http://www.microbeworld.org/component/jlibrary/?view=article&id=6935Murine gammaretroviruses in prostate cancer cell lineshttp://www.microbeworld.org/component/jlibrary/?view=article&id=6903
http://www.microbeworld.org/component/jlibrary/?view=article&id=6903Schistosomiasis posterhttp://www.microbeworld.org/component/jlibrary/?view=article&id=6879
http://www.microbeworld.org/component/jlibrary/?view=article&id=6879Hookworm posterhttp://www.microbeworld.org/component/jlibrary/?view=article&id=6878
http://www.microbeworld.org/component/jlibrary/?view=article&id=6878Viruses go greenhttp://www.microbeworld.org/component/jlibrary/?view=article&id=6848
http://www.microbeworld.org/component/jlibrary/?view=article&id=6848XMRV is a recombinant virus from micehttp://www.microbeworld.org/component/jlibrary/?view=article&id=6732
http://www.microbeworld.org/component/jlibrary/?view=article&id=6732New Elsevier Slogan: “It’s All about The Benjamins”http://www.microbeworld.org/component/jlibrary/?view=article&id=6701
http://www.microbeworld.org/component/jlibrary/?view=article&id=6701Canine hepacivirus, a relative of hepatitis C virushttp://www.microbeworld.org/component/jlibrary/?view=article&id=6689
http://www.microbeworld.org/component/jlibrary/?view=article&id=6689WHO decides to keep smallpox stocks....for nowhttp://www.microbeworld.org/component/jlibrary/?view=article&id=6687
http://www.microbeworld.org/component/jlibrary/?view=article&id=6687Not-so-similar fate of identical twins infected with HIV-1http://www.microbeworld.org/component/jlibrary/?view=article&id=6648
http://www.microbeworld.org/component/jlibrary/?view=article&id=6648Ila Singh finds no XMRV in patients with chronic fatigue syndromehttp://www.microbeworld.org/component/jlibrary/?view=article&id=6559
http://www.microbeworld.org/component/jlibrary/?view=article&id=6559Dickson Despommier’s Parasitic Diseases lectureshttp://www.microbeworld.org/component/jlibrary/?view=article&id=6549
http://www.microbeworld.org/component/jlibrary/?view=article&id=6549Retroviruses and amyotrophic lateral sclerosishttp://www.microbeworld.org/component/jlibrary/?view=article&id=6484
http://www.microbeworld.org/component/jlibrary/?view=article&id=6484The press concludes that arboviruses can be sexually transmittedhttp://www.microbeworld.org/component/jlibrary/?view=article&id=6427
http://www.microbeworld.org/component/jlibrary/?view=article&id=6427Baruch S. Blumberg, MD, 1925-2011http://www.microbeworld.org/component/jlibrary/?view=article&id=6412
http://www.microbeworld.org/component/jlibrary/?view=article&id=6412Viruses engineer the ecosystemhttp://www.microbeworld.org/component/jlibrary/?view=article&id=6325
http://www.microbeworld.org/component/jlibrary/?view=article&id=6325Virophage, the virus eaterhttp://www.microbeworld.org/component/jlibrary/?view=article&id=6259
http://www.microbeworld.org/component/jlibrary/?view=article&id=6259Myra McClure on XMRVhttp://www.microbeworld.org/component/jlibrary/?view=article&id=6244
http://www.microbeworld.org/component/jlibrary/?view=article&id=6244Should smallpox virus be destroyed?http://www.microbeworld.org/component/jlibrary/?view=article&id=6214
http://www.microbeworld.org/component/jlibrary/?view=article&id=6214XMRV infection of Rhesus macaqueshttp://www.microbeworld.org/component/jlibrary/?view=article&id=6001
http://www.microbeworld.org/component/jlibrary/?view=article&id=6001Is Vilyuisk encephalitis a viral disease?http://www.microbeworld.org/component/jlibrary/?view=article&id=5949
http://www.microbeworld.org/component/jlibrary/?view=article&id=5949Frederick Hayden on influenza antiviralshttp://www.microbeworld.org/component/jlibrary/?view=article&id=5874
http://www.microbeworld.org/component/jlibrary/?view=article&id=5874A virology course at Columbia Universityhttp://www.microbeworld.org/component/jlibrary/?view=article&id=5872
http://www.microbeworld.org/component/jlibrary/?view=article&id=5872Are all virus particles infectious?http://www.microbeworld.org/component/jlibrary/?view=article&id=5810
http://www.microbeworld.org/component/jlibrary/?view=article&id=58101000 ??), then it’s not that all cells don’t receive “a particle” at MOI=1 – but that they don’t get an “infectious dose”. Not sure how to say it better – enough to initiate an infection.
So why does polio require 1000 virions to make an infectious dose? I don’t buy the idea that most of the particles are not “viable”.
]]>Multiplicity of infectionhttp://www.microbeworld.org/component/jlibrary/?view=article&id=5750
http://www.microbeworld.org/component/jlibrary/?view=article&id=5750Derek Smith on antigenic cartographyhttp://www.microbeworld.org/component/jlibrary/?view=article&id=5700
http://www.microbeworld.org/component/jlibrary/?view=article&id=5700Derek Smith, Professor of Infectious Disease Informatics, University of Cambridge, U.K., has developed a method for visualizing antigenic evolution by creating two-dimensional maps in a process called antigenic cartography. These maps are made with data that provide information on the antigenic properties of the pathogen. In the case of influenza virus, the data come from measuring the ability of an antiviral antibody to inhibit hemagglutination – binding of virions to red blood cells. Such maps show how amino acid changes can affect antibody binding to virus particles, which cannot be done by comparing nucleotide sequences of different virus isolates. By charting influenza virus strains in this way, it should be possible to better understand genetic and antigenic evolution.