Examining the potential of PSMD9 to predict outcome to radiotherapy in cancer patients Some patients respond better to radiotherapy than others. Predicting in advance which patients will not be responsive to radiotherapy will allow doctors to use higher doses of radiation, or drugs to increase the effectiveness of treatment. A group in Leeds have shown that a specific protein, PSMD9, predicts how well breast cancer patients respond to radiotherapy. This […]

Bladder cancer usually develops in the lining of the bladder, and can spread to the muscle surrounding the organ. The most common sign of bladder cancer is blood in the urine, with others including more frequent or sudden urges to urinate or a burning sensation whilst urinating. Smoking is thought to cause around half of all cases of bladder cancer. The number of cases of bladder cancer across Yorkshire […]

Pim-1 chromatic modifier activity associated with myc-dependent gene expression In cells, DNA is closely associated with a number of different proteins which help give it structure and stability. This complex of proteins and DNA is called chromatin. One way in which genes can be turned on and off is by rearranging the chromatin so that areas of DNA become exposed or hidden to certain molecules. PIM1 is a protein that […]

Bowel cancer (also called colorectal cancer) is the third most common type of cancer in England, with 4668 cases diagnosed in Yorkshire in 2010. The symptoms of early bowel cancer can include blood in your stool, a change in normal bowel habits, abdominal pain or unexplained weight loss. Currently everyone aged 60 ”“ 69 is offered bowel cancer screening every two years in England to increase the chances of catching […]

Breast cancer is the most common cancer in women in the UK, but what is less known is that it can affect men too at a rate of around 1 in every 100,000 men affected. In Yorkshire 5350 people were diagnosed with breast cancer in 2010 and the rate that men get breast cancer has doubled in Yorkshire in the last 10 years. The NHS has introduced a screening program […]

Brain cancer, often called glioma, glioblastoma, or meningioma is a cancer that develops from the cells of your brain, the covering of the brain, or the nerves. These tumours are relatively rare, but they are very hard to treat effectively. Treatment is often by surgery, but may also include chemotherapy and radiotherapy depending on the exact type of brain cancer and the location in the brain. More than 30 people […]