The ever-evolving Material Girl has switched up her look again, but it’s more than her style that seems to have changed.

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Madonna’s always been a shapeshifter, her look evolving from New York club kid to Marilyn Monroe 2.0 to PVC-clad dominatrix and beyond. But in the past decade, its Madonna’s new faces, not hairstyles, that have topped her most talked-about looks.

With a new album coming in 2015, the iconic artist covers the December issue of Interview magazine, and looks fresher than ever. No disrespect to the fabulous lighting by European photography team Mert and Markus or expert airbrushing by Interview, but also there’s no denying her unabashed cosmetic supe-me-up.

In the accompanying interview, conducted by David Blaine (yes, the magician), a friend she met “a hundred years ago” (#VampireLove), the 56-year-old covers topics that are more than skin deep. When Blaine asks about “Devil Prays,” a song on her upcoming album, she explains it’s about how drugs can spark a spiritual experience. “A lot of people drop acid or do drugs, because they want to get closer to God,” she says. “But there’s going to be a short circuit, and that’s the illusion of drugs, because they give you the illusion of getting closer to God, but ultimately they kill you.”

Never a big drug person herself, she does admit in the interview that she “tried everything once.” “As soon as I was high, I spent my time drinking tons of water to get it out of my system,” she says. “As soon as I was high, I was obsessed with flushing it out of me.”

This is your Madonna on drugs.

She goes on to say that, these days, her religious communion of choice is prayer, which she not only uses to “call angels,” but to help her to live in the moment. “The ritual of prayer isn’t a religious thing as much as it is having a ritualistic moment to acknowledge things and not take things for granted,” she says.

“For instance: the fact that you wake up and there’s air in your lungs; the fact that you have a job to do; the fact that you have friends; the fact that you have your health. You’re going to do something that’s going to bring you joy. We take these things for granted.”