TAGGEDInstitute for Computational Medicine

Arrhythmias linked to sudden cardiac death are very rare, making it difficult to study how they occur—and how they might be prevented. To make it much easier to discover what triggers this deadly disorder Johns Hopkins scientists constructed a powerful new computer model that replicates the biological activity within the heart that precedes sudden cardiac death.

A team of Johns Hopkins computational scientists and cancer experts devised its own bioinformatics software to evaluate how well current strategies identify cancer-promoting mutations and distinguish them from benign mutations in cancer cells.