Evidence suggests that uptake of NICE guidance is variable. Only the implementation of technology appraisal guidance is mandatory for NHS organisations

Implementing NICE guidance requires change – influences of change may be categorised into three clusters: the innovation itself, the characteristics of the people involved and the context of its introduction

Key elements to successful implementation of NICE guidance include: board support, clear leadership, a NICE manager, support from a multidisciplinary team, a systematic approach to implementation/financial planning and a process to evaluate uptake and feedback