KAAD-Cyclopamine

Brand: Stemolecule™Product Code: 04-0028

KAAD-cyclopamine is a sonic hedgehog antagonist known to target Smoothened, a 7-transmembrane receptor of the hedgehog signaling pathway. KAAD-cyclopamine halts the migration or proliferation of a variety of cancer cells (e.g. esophageal, gastrointestinal, hepatic and pancreatic cancer).