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We thank Dr. Riopelle for his question. In the article,1 table 2 contains the results of unadjusted comparisons across study arms for all pain endpoints. In addition to these unadjusted comparisons, for the study’s primary endpoint an analysis was performed to assess differences across study arms after adjusting for sex, American Society of Anesthesiologists status, and type of anesthesia. In all cases, the results of the unadjusted and adjusted comparisons across treatment groups were consistent.