Uses

In the United States, Bicillin C-R (a
injectable suspension which 1.2 million units of benzathine penicillin & 1.2 million
units of procaine penicillin per 4 mL) is not recommended for
treating syphilis, since it contains only half the recommended dose
of benzathine penicillin. Medication errors have been made due to
the confusion between Bicillin L-A &
Bicillin C-R.[2] As a
result, changes in product packaging have been made; specifically,
the statement "Not for the Treatment of Syphilis" has been added in
red text to both the Bicillin CR and Billin CR 900/300 syringe
labels.[3]