Oncology Test Further Highlights Broad Market Applicability of GeneXpert System
SUNNYVALE, Calif., June 17 /PRNewswire-FirstCall/ -- Cepheid (Nasdaq: CPHD ) today announced the release of its improved Xpert(R) BCR-ABL Monitor test to be marketed as a CE IVD product under the Euro...

People with schizophrenia have an increased number of unusual chromosomal changes, particularly structural changes that have the potential to alter the function of the genes. These results were published today in the scientific journal Nature .
Research scientists found changes in the structur...

Barcelona, Spain: Prenatal biochemical screening tests are widely used to look for chromosomal abnormalities in the fetus which can lead to serious handicap, or even death during gestation or in the first few days after birth. But these tests are only able to detect fewer than half of the total ...

A new technique could pave the way toward screening people at risk for lung cancer for the genetic changes that may foreshadow malignancies, researchers from the University of Colorado say.
The most successful way to reduce mortality in cancer is prevention, said researcher Wilbur A. Franklin, ...

Commercially available gene chips have been used by a pediatric research team to scrutinize all of a patient’s chromosomes in order to identify small defects that lead to genetic diseases //.
Because currently used genetic tests usually cannot detect these abnormalities, the new research may l...

ROCKVILLE, Md. and NEW YORK, Jan. 27 /PRNewswire-USNewswire/ -- Researchers from the J. Craig Venter Institute (JCVI) and the Ludwig Institute for Cancer Research (LICR) have uncovered new genomic alterations that lead to gene fusions in a breast cancer cell line by using 454 Life Sciences sequenc...

...mosomes in a cell. Normal human cells have two copies of each
chromosome. Cancer cells will often duplicate or lose pieces of chromosomes, and these chromosomal changes can help physicians categorize a tumor, determine its aggressiveness, and/or determine which tumors will respond to specific drugs.
With...

...use of the ClariSure aCGH postnatal test as an aid in detecting copy-number chromosomal abnormalities implicated in dozens of medical conditions, including mental ...ted the ClariSure test's ability to use a single blood specimen to identify chromosomal abnormalities associated with dozens of disorders, including Down, cri du c...

...omprehensive test yet developed for the detection of
fetal aneuploidies, the presence of extra chromosomes, which cause Down
syndrome (T-21) and other chromosomal abnormalities.
Risk assessment for Down syndrome is routinely offered to patients in the
first and/or second trimester of pregnancy. These eval...

...he development of an improved first and second trimester non-invasive fetal chromosomal screening test to detect Down syndrome and other genetic fetal conditions. ...ghly accurate screening for common fetal autosomal (Trisomy 18, 21) and sex chromosomal (47, XXY) chromosome abnormalities is feasible, particularly in the first t...

...ase or monitor response to
therapy.
The discovery, titled "Prostate specific membrane antigen associates
with anaphase promoting complex and induces chromosomal instability," is
outlined in the July issue of Molecular Cancer Therapeutics, an American
Association for Cancer Research journal and provides new ins...

Description:...nding technology to attain the earliest gender detection with unprecedented sensitivity and unsurpassed accuracy. The technique traces the amount of Y chromosomal DNA in the maternal blood to determine gender. Here's how it works: Your baby releases its DNA into your blood plasma. Because DNA between different p...Company:Acu-Gen Biolab, Inc.

Description:...gnificant chance of miscarriage. As a result, the current standard care offers invasive prenatal baby gender testing only to those women whose risk of chromosomal or genetic abnormalities are greater than or equal to the risk of a procedure-related loss. This means that the vast majority of women never receive t...Company:Paragon Genetics

...tions, of which monosomy X is most common. It is a chromosomal disorder in which all or part of one of the sex c... Turner Syndrome . Turner syndrome is a chromosomal condition that affects development in females. ......some of females that ... Turner syndrome is a chromosomal condition that alters development in females. ... ...

... common autosomal... Trisomy 18 , also called Edwards syndrome, is a chromosomal condition associated ... Individuals with trisomy 18 often have a low ...alies and severe to ... Trisomy 18 in the embryo/fetus is also a common chromosomal cause of ... Trisomy 18 is also called "Edwards syndrome," named af...

...enetic messages are confused and ... Trisomy 13 (also called Patau Syndrome) occurs in up to 1 out of 5,000 ... Trisomy 13 Syndrome is a rare chromosomal disorder in which all or a portion of ... In addition, those with trisomy 13 mosaicism typically have less severe symptoms; ... The term " tri...

... Patau syndrome, also known as trisomy 13 and trisomy D, is a chromosomal abnormality, a syndrome in which a patient has an additional chromosome 13 due to a non-disjunction of chromosomes during meiosis. Some are ca...

... Sex linkage is the phenotypic expression of an allele that is related to the chromosomal sex of the individual. This mode of inheritance is in contrast to the inheritance of traits on autosomal chromosomes, where both sexes have the same...

Amsterdam, The Netherlands: One-step screening for both genetic and chromosomal abnormalities has come a stage closer as scientists announced that an embryo test they have been developing has successfully screened cells taken from spare embryos that were known to have cystic fibrosis.
They tol...

NEW YORK (Dec. 19, 2007) -- Approximately one in every 500 to 650 baby boys is born with an extra X chromosome, a variation in their genetic code that until a few years ago was thought to result in infertility in all cases. However, this is no longer the case. A recent conference hosted by NewYork...

Researchers have a new understanding of the process cells use to ensure that sperm and eggs begin life with exactly one copy of each chromosome ?a process that must be exquisitely regulated to prevent problems such as miscarriages and mental retardation. The new work reveals how gluelike protein co...

A pediatric research team has used commercially available gene chips to scrutinize all of a patient's chromosomes to identify small defects that cause genetic diseases. Because currently used genetic tests usually cannot detect these abnormalities, the new research may lead to more accurate diagnos...

...ndings are published in the July 31 edition of the Journal of Biological Chemistry , available online now.
Previously the researchers found that a chromosomal inversion a genetic misalignment, where part of the chromosome containing the DLX5 gene gets flipped around during cell division cooperates with ano...

...otide arrays through a partnership with Baylor College of Medicine . Large chromosomal abnormalities that are associated with over 270 genetic syndromes can be ea...ted and genome-wide studies (GWAS). Array CGH is used to detect genome-wide chromosomal imbalances with a single laboratory test consisting of multiple probes targ...

...rectal cancer cases and controls, identifying all variants residing in this chromosomal region common to colorectal cancer patients.
Houlston and colleagues the...ery likely the causal basis for colorectal cancer risk associated with this chromosomal region.
Houlston explained, "Our efforts show that many different method...

...g elsewhere in the chromosomes. This suggests that chromosomal organization plays an important evolutionary role,...nes function.
Scientists once hypothesized that chromosomal breakage and recombination occurred randomly along...at the breakpoints occurred more often in specific chromosomal regions than in others.
In 2004, Lewin and his ...

...ncluding a form of mental retardation and other neurological and birth defects.
In the domestic cattle genome, researchers found that some of these chromosomal rearrangements affect genes related to immunity, metabolism, digestion, reproduction and lactation. For instance, researchers think some of these chan...

Description:... chromosomal Grade Agarose was developed specifically for pulsed field separations of DN...ation of very low percentage agarose gels. Megabase DNA separations done in chromosomal Grade
Agarose are up to 50% faster than with ...Company:Bio-Rad

Description:... plays an integral role in proofreading the nascent strands in DNA
replication, in transcription-coupled nucleotide excision repair and in preventing chromosomal recombination between different species of bacteria. Mut S binds to DNA specifically at base pair mismatches and small (<4 nt) insertions and deletion...Company:USB Corp.

...plasmid is integrated, the transferred DNA consists of the F-plasmid sequence plus an amount of chomosomal DNA from the donor bacterium. The amount of chromosomal DNA that is transferred depends on how long the bacteria hold contact; the transfer of the whole bacterial chromosome would take about 100 minutes. Th...

...brain disorders are congenital . Tay-Sachs disease , Fragile X syndrome , Down syndrome , and Tourette syndrome are all linked to genetic or chromosomal errors. Malfunctions in the embryonic development of the brain can be caused by genetic factors or by drug use or disease in the mother.
Brai...

...nes . Oncogenes promote cancer when "switched on" by a mutation, whereas tumor suppressor genes prevent cancer unless "switched off" by a mutation. chromosomal translocation , such as the Philadelphia chromosome , is a special type of mutation and may involve oncogenes or tumor suppressor genes. In general, ...

...es
5 Karyotype
6 Human chromosome
7 chromosomal aberrations
8 See also
9 External links .... It seems to serve structural purposes during the chromosomal stages. Heterochromatin can be further distinguish...ve a small number of unclonable gaps. [1]
chromosomal aberrations
Some chromosome abnormalities do no...

...sity of organismal form in an evolutionary context.
The findings of developmental biology can help to understand developmental malfunctions such as chromosomal aberrations , for example, Down syndrome . An understanding of the specialization of cells during embryogenesis may shield information on how to sp...

...er of cases of trisomy 21 are due to mosaicism. ... Online support groups for those whose lives have been touched by the diagnosis of a trisomy chromosomal disorder. Trisomy 13, also called Patau syndrome, is a genetic disorder associated with ... Partial trisomy -- the presence of a part of an ext...

...is connected to the right ... Information about transposition in the free online ... transposition - (genetics) a kind of mutation in which a chromosomal segment is ... Transposition of the great arteries is a congenital (present at birth) heart defect. ... After a transposition of the grea...

...n. A change of location. Genetics. A transfer of a chromosomal segment to a new position, especially on a nonho...logous chromosome ... Translocation ... Other chromosomal translocations may occur more frequently in the ... that carry chromosomal translocations are typically healthy; ... Tr...

... Synapsis is the pairing of two homologous chromosomes that occurs during meiosis. It is a form of chromosomal crossover. Synapsis takes place during prophase I. When homologous chromosomes synapse, they come closer together until they are connected by a ...

(Date:3/3/2015)... New York, NY (PRWEB) March 03, 2015 ... sleepy this spring. Sanjeev Kothare, MD, has tips for parents. ... tired come March 8 at 2:00 a.m. when they set ... because when you wake up that day -- one hour ... sleep. , That’s why parents should start thinking about “sleep ...

(Date:3/3/2015)... 03, 2015 Sunday, March 1, through Saturday, ... the time of year, every region of the country is ... why Amica Insurance is sharing the following tips ... to help keep you safe in the event of severe ... Change wet clothing frequently to prevent loss of body heat. ...

(Date:3/3/2015)... March 03, 2015 According to ... http://www.idataresearch.com ), market saturation has made neurosurgery navigation ... the United States. Unit sales growth moderately increased ... as facilities replace older systems, and as new ... market is very much a replacement and upgrade ...