Abstract:Skin,like other human organs, skin anginghappens with time. But different from other organs, an importantenvironmental factor affecting skin aging is ultraviolet radiation . With the increase of ozone hole in the atmosphere, theaggravation of environmental light pollution and the improvement of people’s living standard, people pay more and moreattention to the changes of skin caused by photo damage and photoaging, such as erythema, wrinkles, pigmentation andelasticity decline. Therefore, the research on the mechanism and treatment of photoaging has become a hot topic. However,natural photoaging is a long process, so most of the experiments of photoaging is a step after the establishment of theexperimental animal model of photoaging. Therefore, it is important to establish a reliable model closer to the naturalphotoaging of human skin. This review mainly summarizedthe mechanism of photoaging, the modeling methods of photoaging,and the progress of detection standard.