Tumors with MYCN amplification had a unique genomic signature of 1p deletion and 17q gain, but few other rearrangements. (17647283)

Tumors with an aggressive clinical phenotype without MYCN amplification, showed multiple structural rearrangements. Most notable were deletions of 3p, 4p, and 11q and gain of 1q, 2p, 12q, and 17q. (17647283)

There is a subset of tumors with an aggressive clinical phenotype and no detectable DNA CNAs. (17647283)