1Department of Pathology, Faculty of Veterinary Medicine, Mustafa Kemal University, TR- 31060 Hatay - TURKEY2Department of Pathology, Faculty of Veterinary Medicine, Ankara University, TR-06110 Ankara - TURKEY3Department of Microbiology, Faculty of Veterinary Medicine, Ankara University, TR-06110 Ankara - TURKEY
DOI :
10.9775/kvfd.2017.18879
Tuberculosis and tumors are two major health problems in both humans and animals; and there are still many question marks in the
association between these two important diseases. In this case, progressive malignant mixed tumor and productive tuberculosis were
observed simultaneously in 8 years old, terrier, and female dog. After mastectomy of the left mammary chain; removed tissue was brought
for pathological examination. For the histopathology examination, specimens were fixed in 10% neutral buffered formalin. Tissues were
processed routinely and stained with hematoxylin-eosin and Ziehl-Neelsen for acid-fast bacilli detection. Microscopically, atypical neoplastic
cells and caseation necrosis located in the center of tubercle were seen. After these findings, Mycobacterium spp. was investigated in the
same sample and was confirmed by PCR amplification. Concomitant tuberculosis and neoplasm, previously reported in only a goat, is a rare
occurrence in domestic animals.
Keywords :
Dog, Histopathology, Malignant mixed tumor, Mycobacterium spp.