Giuliana Rancic Back to Work After Successful Double Mastectomy

Miss California Alyssa Campanella (R) answers a question with show hosts Andy Cohen (L) and Giuliana Rancic during the 2011 Miss USA pageant in the Theatre for the Performing Arts at Planet Hollywood Hotel and Casino in Las Vegas, Nevada June 19, 2011. Campanella was later crowned Miss USA 2011.

Television personality Giuliana Rancic has returned to work Tuesday night for the first time since her double mastectomy surgery just two weeks ago.

"It is so good to be back," she said in the opening of the show. "Thank you, all of you, once again for your love, your support, your prayers. Means the world to me, thank you so much!"

Rancic further showed her excitement and appreciation for being back to work by tweeting shortly before going on air, "back at work today since surgery. Excited to be on set of @ENews. I've missed my 2nd family (co-workers and you guys!!!) #thankful."

The star of "Giuliana & Bill" told E News, "Thankfully, I've been feeling better every single day since surgery and this weekend my doctors gave me the green light to get back to work."

She continued, "Even though I moved a tad slower than usual today, everyone welcomed me back with open arms and it was a wonderful homecoming."

Rancic had reservations about coming back early, but in the long run was happy she did it. "I wasn't sure whether I was going to return to E! News this week or after the new year. The last thing I wanted to do was rush my recovery," reported RealityTVWorld.

The "E! News Live" host was recently diagnosed with breast cancer in October, and had already undergone an unsuccessful lumpectomy.

She and her husband Bill, decided the mastectomy was the route to go instead of having a double lumpectomy, reported NBC.

She explained that some of the pros of the surgery would be not having to worry about future mammograms and allowing her to possibly have children sooner.

After her first surgery in October Bill told E!, "Giuliana has had a tough year and a half. Between the IVF attempts and now with this, I wish I could carry some of the load. Watching her being wheeled into the [operating room] was heartbreaking for me."

Giuliana had spoken about her health issues and her public battle with trying to get pregnant as well.

"Sometimes I have to get [injections] 21 days in a row, three times a day. It's a lot. But you've got to do it," she said.

"I still have a long road ahead, but thanks to everyone's overwhelming love, support and prayers, it will be an easier journey."

Rancic told Ryan Seacrest in an interview that she felt she needed to come public about her diagnosis, in an effort to help empower and encourage woman everywhere to get tested.

“I feel like such a heavy weight has been lifted off my shoulders,” she told Seacrest concerning her condition. “I've been keeping this secret from a lot of dear friends for a while now and it’s nice to get it out there and not hide anymore.”