Information about Hyzaar.

Serious side effects have been reported with HyzaarSee theHyzaar Precautionssection.

This medication is not recommended for use during pregnancy due to the risk for harm to an unborn babyConsult your doctor for more detailsSee also Warning section

Your blood pressure will need to be checked oftenYour kidney function may also need to be testedVisit your doctor regularly.

Hyzaar is a combination of losartanCozaarand hydrochlorothiazide and is used for treating high blood pressureLosartan is an oral medication that belongs to a class of drugs called angiotensin receptor blockersARBsOther ARBs include irbesartanAvaprovalsartanDiovanand candesartanAtacandAngiotensinformed in the blood by the action of angiotensin converting enzymeACEis a powerful chemical that attaches to angiotensin receptors found in many tissues but primarily on smooth muscle cells surrounding blood vesselsAngiotensin’s attachment to the receptors causes the muscles to contract and the blood vessels to narrowvasoconstrictwhich leads to an increase in blood pressurehypertensionLosartanmore specificallythe chemical formed when the liver converts the inactive losartan into an active chemicalblocks the angiotensin receptorBy blocking the action of angiotensinlosartan relaxes the musclesdilates blood vessels and thereby reduces blood pressure.

What is losartan and hydrochlorothiazideand how does it workmechanism of action