Other locations on the Seward Peninsula include the mining towns of Council, Solomon, Candle, Haycock and Taylor. While still frequented by locals of neighboring communities, there are no longer year round residents in these locations. There is a United States Coast GuardLORAN station at Port Clarence. The U.S. Air Force operates a radar station at the "Tin City" site, 7 miles (11 km) southeast of Wales.

Much of the peninsula is part of the Bering Land Bridge Preserve, administered by the National Park Service

The Seward Peninsula has several distinct geologic features. The Devil Mountain Lakes on the northern portion of the peninsula are the largest maar lakes in the world. They were formed over 21,000 years ago as the result of an underground steam explosion.[4] The Killeak Lakes and White Fish Lake are also volcanic maar lakes of notable size on the northern Seward Peninsula. Four mountain ranges line the southern side of the peninsula, the most prominent being the Kigluaik (or Sawtooth) Mountains. The highest point in the range and the peninsula is the peak of 4,714-foot (1,437 m) Mount Osborn. Other mountain ranges on the Seward Peninsula include the Bendeleben Mountains, Darby Mountains, and York Mountains. The Lost Jim Lava Flow north of Kuzitrin Lake is a lava field formed roughly 1,000 to 2,000 years ago, which covers roughly 88 square miles (228 km2).
Several geothermal hot springs are located throughout the peninsula, including Serpentine Hot Springs, Pilgrim Hot Springs, Granite Mountain, Elim, Clear Creek and Lava Creek.

The Seward Peninsula is the western-most limit of distribution for the Black spruce, Picea mariana, a dominant overstory species of the region.

Alaska's reindeer herding was concentrated on Seward Peninsula ever since the first shipment of reindeer were imported there from eastern Siberia in 1892.[5] It was believed that migrating caribou, could be prevented from mingling with the domesticated reindeer on the Peninsula because of the geography of the peninsula, thereby avoiding loss of reindeer that might wander off with caribou.[5][6] However, in 1997 the domesticated reindeer joined the Western Arctic Caribou Herd on their summer migration and disappeared.[7]

Cape Prince of Wales, the westernmost point on the mainland of the Americas, is on the western tip. The cape is only 51 miles (82 km) from Cape Dezhnev, the closest point on the Russian mainland. In August 2011 Russia announced an ambitious project to construct a rail tunnel under the Bering Strait, linking the Seward Peninsula in Alaska with the Chukchi Peninsula in Russia. If completed, the project would cost an estimated US $65 billion and would be the world's longest tunnel at 103 km (64 mi) long.[8]