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Publication date: Available online 15 December 2018Source: Journal of Minimally Invasive GynecologyAuthor(s): Huiying Zhang, Huixia Zhang, Xueqing He, Wenyan Tian, Xueru SongABSTRACTEndometrial polyps are frequently encountered in the uterine cavity of infertile women. There is much debate regarding the treatment of endometrial polyps in patients who are undergoing assisted reproductive technology (ART). A systematic review was performed by searching PubMed, Embase, and the Cochrane Library for retrospective or prospective studies that compared the effect of hysteroscopic resection of polyps with no treatment on pregnancy ...

Endometrial polyps are frequently encountered in the uterine cavity of infertile women. There is much debate regarding the treatment of endometrial polyps in patients who are undergoing assisted reproductive technology (ART). A systematic review was performed by searching PubMed, Embase, and the Cochrane Library for retrospective or prospective studies that compared the effect of hysteroscopic resection of polyps with no treatment on pregnancy outcomes of patients who underwent ART. Primary outcomes were clinical pregnancy, live birth, miscarriage, and implantation rate after ART.

Abstract
A balanced Robertsonian translocation results from fusion of two acrocentric chromosomes. Carriers are phenotypically normal, and are often diagnosed because of recurrent miscarriages, infertility or aneuploid offspring. Mortality and site-specific cancer risks in carriers have not been prospectively investigated. We followed 1987 carriers diagnosed in Great Britain for deaths and cancer risk, over an average of 24.1 years. Standardised mortality (SMR) and incidence (SIR) ratios were calculated comparing the number of observed events against population rates. Overall mortality was raised for carriers diagnosed aged

CONCLUSIONS: Despite the significant proportion and recent growth of Catholic health care within the U.S. health care sector, little is known about reproductive health outcomes in these settings and in comparison with other settings.
PMID: 30531578 [PubMed - as supplied by publisher]

Asherman syndrome (AS) is a condition defined by the presence of intrauterine adhesions (IUAs) resulting when the bona fide endometrium is replaced by fibrotic tissues, causing the uterine walls to adhere to one another and causing symptoms such as infertility, recurrent miscarriage, menstrual abnormalities, pelvic pain, and abnormal placentation. A successful treatment for AS requires a comprehensive approach and prevention seems to be paramount and starts by optimizing the diagnostic strategy (1 –3).

ConclusionFCM is widely used to assess cellular populations, but not typically employed for endometrial evaluation. FCM provides a rapid, detailed, and quantitative analysis and reduces inter-observer subjectivity bias. Detailed understanding of the normal endometrial immunophenotype, and associated deviations, may provide insight into the aetiology of infertile patients labelled “unexplained”. Failure despite transfer of high grade, or proven euploid blastocysts, is a difficult problem, and endometrial profiling may help identify research areas to determine potential future therapeutic interventions for this d...

AbstractThe aging-related decline in fertility is an increasingly pressing medical and economic issue in modern society where women are delaying family building. Increasingly sophisticated, costly, and often increasingly invasive, assisted reproductive clinical protocols and laboratory technologies (ART) have helped many older women achieve their reproductive goals. Current ART procedures have not been able to address the fundamental problem of oocyte aging, the increased rate of egg aneuploidy, and the decline of developmental potential of the eggs. Oocyte maturation, which is triggered by luteinizing hormone (LH) in vivo...

Background.Infertility is common after HCT predominantly as a result of the chemoradiotherapy used in conditioning. Patients are increasingly encouraged to store gametes, tissue or embryos before transplant for use after their potentially sterilising treatment. Furthermore, some patients do retain or recover fertility and conceive naturally.Methods:We sent questionnaires to 602 EBMT centers requesting retrospective details of number of pregnancies following either allogeneic or autologous HCT, use of artificial reproductive techniques (ART) and pregnancy outcome for all patients treated between 1995-2015.Results:47 centers...

Constitutional (germline) chromosomal rearrangements, including translocations and inversions, are well recognized for their potential to impact fertility and miscarriage risk [1,2]. Conventional chromosome studies are routinely performed on adult patients with histories of infertility or recurrent miscarriages, and it is under these circumstances when constitutional rearrangements are often revealed [1,2]. However, in this context, carriers of constitutional rearrangements are often phenotypically and cognitively normal (assuming the rearrangements are truly balanced and genes of clinical significance are intact) and thes...