The paper details our work on creating stereoregular cyclopolyethers. Ring-closing metathesis from an isotactic polyether affords the target cyclopolyether. Stereoselective cis-dihydroxylation gives a PEGose framework that mimics the helical ladder structure of amylose. This topological control of synthetic polymer frameworks is a really tough challenge in polymer science in the quest for biopolymer mimics. Great work!