Embedded electrical and optical biosensors to monitor behavior of tissues

Optimizing these techniques for high throughput and scale up

Approach: Dynamic scaffolds provide cues to direct cells

The key attribute is dynamic scaffolds, where we can independently control the composition and mechanical environment. At the heart is the cardiac test bed—3D Printing, multiscale patterning to build cardiomyocyte scaffolds with micron-scale features and cm-size extent. Next, deploy actuators to drive scaffold movement, followed by nanoscale patterning —provided by Thrust Area 1. Following that:

Both organic compounds for cell adhesion and both metals for embedded biosensor fabrication