{2532} Primeκαίkai{kahee}Apparently a primary particle, having a copulative and sometimes also a cumulative force; and, also, even, so, then, too, etc.; often used in connection (or composition) with other particles or small words.

{3004} Primeλέγωlego{leg'-o}A primary verb; properly to 'lay' forth, that is, (figuratively) relate (in words [usually of systematic or set discourse; whereas G2036 and G5346 generally refer to an individual expression or speech respectively; while G4483 is properly to break silence merely, and G2980 means an extended or random harangue]); by implication to mean.

{0846} Primeαὐτόςautos{ow-tos'}From the particle αὖ [[au]] (perhaps akin to the base of G0109 through the idea of a baffling wind; backward); the reflexive pronoun self, used (alone or in the compound of G1438) of the third person, and (with the proper personal pronoun) of the other persons.

Mark 8:21

_ _ How is it that ye do not understand?  “do not understand that the warning I gave you could not have been prompted by any such petty consideration as the want of loaves in your scrip.” Profuse as were our Lord’s miracles, we see from this that they were not wrought at random, but that He carefully noted their minutest details, and desired that this should be done by those who witnessed, as doubtless by all who read the record of them. Even the different kind of baskets used at the two miraculous feedings, so carefully noted in the two narratives, are here also referred to; the one smaller, of which there were twelve, the other much larger, of which there were seven.

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Mark 8:21

And he said unto them, (c) How is it that ye do not understand?

(c) How does it come to pass that you do not understand these things which are so plain and evident.

How:

Mark 8:12 And he sighed deeply in his spirit, and saith, Why doth this generation seek after a sign? verily I say unto you, There shall no sign be given unto this generation.Mark 8:17 And when Jesus knew [it], he saith unto them, Why reason ye, because ye have no bread? perceive ye not yet, neither understand? have ye your heart yet hardened?Mark 6:52 For they considered not [the miracle] of the loaves: for their heart was hardened.Mark 9:19 He answereth him, and saith, O faithless generation, how long shall I be with you? how long shall I suffer you? bring him unto me.Psalms 94:8 Understand, ye brutish among the people: and [ye] fools, when will ye be wise?Matthew 16:11-12 How is it that ye do not understand that I spake [it] not to you concerning bread, that ye should beware of the leaven of the Pharisees and of the Sadducees? ... Then understood they how that he bade [them] not beware of the leaven of bread, but of the doctrine of the Pharisees and of the Sadducees.John 14:9 Jesus saith unto him, Have I been so long time with you, and yet hast thou not known me, Philip? he that hath seen me hath seen the Father; and how sayest thou [then], Shew us the Father?1 Corinthians 6:5 I speak to your shame. Is it so, that there is not a wise man among you? no, not one that shall be able to judge between his brethren?1 Corinthians 15:34Awake to righteousness, and sin not; for some have not the knowledge of God: I speak [this] to your shame.