Alternative to Metoprolol Succinate

Leigh A. Zaykoski

Metoprolol succinate is an extended-release version of metoprolol. This drug is a beta blocker that is used to treat high blood pressure and other heart conditions. While many patients can take this drug with no problems, an alternative to metoprolol succinate may be needed if it does not control blood pressure adequately or causes unpleasant side effects.

Beta Blockers

Metoprolol succinate is just one of many drugs known as beta blockers. These medications block the effects of epinephrine on the heart, which slows the heartbeat and reduces blood pressure. These drugs also improve blood flow, reducing the force of the heartbeat. If metoprolol succinate is not effective, other beta blockers may be used to control blood pressure. Examples of beta blockers include bisoprolol, atenolol and propranolol.

Calcium Channel Blockers

Calcium channel blockers relax the blood vessels and reduce the pumping strength of the heart. In addition to treating high blood pressure, these drugs can also be used to treat heart arrhythmia and chest pain. Those with heart failure or with structural damage to their heart muscles should avoid calcium channel blockers. Examples of calcium channel blockers include verapamil, diltiazem and nifedipine.

ACE Inhibitors

ACE inhibitors, also known as angiotensin-converting enzyme inhibitors, are used to treat hypertension and heart failure. This type of drug may also be used to slow kidney failure in diabetic patients. ACE inhibitors work by preventing an enzyme from narrowing the blood vessels and releasing hormones that contribute to an increase in blood pressure. When the blood vessels are relaxed, the heart can beat with less force, reducing blood pressure. Examples of ACE inhibitors include lisinopril, captopril, enalapril, fosinopril and quinapril.

Diuretics

Diuretics are used to treat high blood pressure and congestive heart failure. They reduce the amount of water in the body by working with the kidneys to increase the amount of urine that is produced. The three types of diuretics are loop diuretics, thiazide diuretics and potassium-sparing diuretics. All three types relax the blood vessels and reduce cardiac output and blood volume. Patients who are taking loop or thiazide diuretics need to consume adequate amounts of potassium, as increased urine production can cause a reduced potassium level in the body. Examples of diuretic drugs include hydrochlorothiazide, furosemide and amiloride.