Kerlone

DRUG DESCRIPTION

Kerlone (betaxolol hydrochloride) is a β1-selective (cardioselective)
adrenergic receptor blocking agent available as 10-mg and 20-mg tablets for
oral administration. Kerlone (betaxolol hydrochloride) is chemically described as 2-propanol, 1-[4-[2-(cyclopropylmethoxy)
ethyl] phenoxy]-3-[(1-methylethyl) amino]-, hydrochloride, (±). It has
the following chemical structure:

Betaxolol hydrochloride is a water-soluble white crystalline powder with a
molecular formula of C18H29NO3·HCl and a molecular
weight of 343.9. It is freely soluble in water, ethanol, chloroform, and methanol,
and has a pKa of 9.4.

What are the precautions when taking betaxolol hydrochloride (Kerlone)?

See also warning section.

Before taking betaxolol, tell your doctor or pharmacist if you are allergic to it; or to other beta blockers (e.g., atenolol, metoprolol); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain types of irregular heartbeats (e.g., sinus bradycardia, second- or third-degree atrioventricular block), a certain serious heart condition (cardiogenic shock), uncontrolled severe heart failure, a certain type of tumor (untreated pheochromocytoma).