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Washington University School of Medicine neuroscientists have attached the light-sensing protein rhodopsin to opioid receptor parts to activate the receptor pathways using light from a laser fiber-optic device. They also influenced ...

UNC researchers uncovered a cellular mechanism by which kappa opioid receptors drive anxiety. These proteins inhibit the release of the neurotransmitter glutamate in a part of the brain that regulates emotion. KORs are targets for t...

Researchers found initial confirmation that a novel scaffold protein previously unassociated with the mu opioid receptor (MOR) regulates MOR-induced signaling activation. The MOR is the target of opioid drugs like morphine and is an...

In a new study, researchers have characterized the effects of a series of opioids on proteins in the brain other than opioid receptors. In the British Journal of Pharmacology study, several synthetic opioids inhibited serotonin and ...