Romeo × Juliet (ロミオ×ジュリエット, Romio to Jurietto) is a TV anime series, loosely based on William Shakespeare's classical play, Romeo and Juliet, along with numerous references and characters from other Shakespearean plays. Though the anime borrows mostly from Shakespeare's story, the manga adaptation differs extensively from the original. Romeo x Juliet was broadcast in Japan on Chubu-Nippon Broadcasting from April 4, 2007 to September 26, 2007. In 2009, Romeo x Juliet was dubbed into English and released by Funimation Entertainment.

Fourteen years ago in the floating island of Neo Verona, Leontes Montague and his men led a bloody coup and murdered all of the members of House Capulet, the rulers of Neo Verona. However, one survivor, Juliet, was able to escape thanks to a group of Capulet loyalists. Fourteen years later, Leontes, the new Prince of Neo Verona, rules the land with an iron fist and crushes anyone who opposes him. Juliet, now a sixteen-year-old girl, fights against House Montague's oppression by becoming a masked vigilante known as "The Crimson Whirlwind". While attending the Rose Ball hosted by the Montagues with a friend, Juliet meets Romeo, Prince Montague's son and both of them fall in love at first sight. Unlike his father, Romeo is a kind and humble man who is opposed to his father's cruelty and shares many ideals with Juliet. Unfortunately for them, Capulet loyalists are planning a rebellion to overthrow House Montague while Leontes is obsessed with destroying the threat of House Capulet permanently. As these star-crossed lovers face many challenges and adventures together which will strengthen their love, an ancient secret hidden within Neo Verona is slowly revealed.