Sodium in the structure of The Structure of DPP4 in Complex With An Oxadiazole Inhibitor (pdb 2hha)

The binding sites of Sodium atom in the structure of The Structure of DPP4 in Complex With An Oxadiazole Inhibitor (pdb code 2hha). This binding sites where shown with 5.0 Angstroms radius around Sodium atom. The 2hha structure was solved by G.SCAPIN, with X-Ray Crystallography technique, brief refinement statistics is given in the table below:

Resolution (A)

30.0-2.4

Space group

P212121

a (A)

117.971

b (A)

125.584

c (A)

136.716

alpha (°)

90.00

beta (°)

90.00

gamma (°)

90.00

Rfactor (%)

18.5

Rfree (%)

23.3

Sodium Binding Sites:

Sodium binding site 1 out of 1 in 2hha

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Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Sodium in the PDB 2hha. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Sodium atom, shown by VdW sphereResidues shown as a stick model or VDW spheres: A: Gly490, A: Leu491, A: Arg492,