Eleven people were killed in separate head on collisions on opposite sides of the country today - including a tragic family of four.

In Tampa, Florida, five men, including four fraternity brothers, lost their lives on a southwest Florida highway early this morning when a suspected drunk driving on the wrong-side of the road smashed into their car.

And in Diamond Bar, California, a family of four perished in massive 100mph pileup after a Camaro driving the wrong way down the freeway slammed head-on into their SUV.

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The driver: Olivia Culbreath, 21, has been identified by authorities as the driver of the wrong-way Camaro

Devastating: A family of four is among the six people killed Sunday morning in a suspected drunk-driving wrong-way crash in California

Hunting for clues: Officials investigate the scene of the horrific accident

The driver of the Camaro, Olivia Culbreath, 21, survived the 4.45am crash and police have indicated that they believe she was intoxicated at the the time of the collision which also caused the death of two of Culbreath's passengers.

Culbreath and another passenger are currently in intensive care at a local hospital and authorities said that two of the victims were ejected from the vehicles in the tragic smash.

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In Florida, a Ford Expedition heading south in the northbound lanes of Interstate 275 in Tampa collided head-on with a Hyundai Sonata about 2am.

Victims: Jobin Joy Kuriakose, 21 (left) and Ankeet Patel, 22 (right) died when an SUV plowed into their vehicle

Victims: Dammie Yesudhas (left) and Imtiyaz Ilias, 20 (right) were University of South Florida students

As the Ford burst into flames, killing the unidentified driver, the Hyundai's four young passengers succumbed to their injuries.

Due to extensive fire damage, officials are working to identify the male driver of the Ford who was in his early 20s.

Police have identified the victims in the other car as Jobin Joy Kuriakose, 21, Ankeet Harshad Patel, 22, Imtiyaz 'Jim' Ilias, 20 and Dammie Yesudhas, 21 - all members of University of South Florida's Sigma Beta Rho fraternity.

News of the horrific crash has rocked the close-knit fraternity, with condolences rolling in after Sigma Beta Rho Fraternity, Inc posted this touching message on the Facebook page:

'RIP to four of our brothers from Mu Chapter at USF in Tampa who we lost early this morning from a car crash.