The design of the V268 Ultrasonic guitar was doubtlessly influenced by the growing popularity of the Gibson ES-335 in the late 1960s. By including a series of battery powered onboard special effects in their "335 style" model, Vox hoped to lure customers away from a Gibson.

The 1968 US Vox price list indicated that the retail price of the Ultrasonic guitar was $450 USD. In 2011 dollars, the Ultrasonic would retail for about $2875.

The Ultrasonic guitar was produced for Vox in Italy by EKO in Recanati Italy. A decal on the back of each guitar states: "Made by Vox in Italy."

The circuitry for all the onboard effects (treble/bass booster, distortion, and repeat percussion) in the Ultrasonic guitar was designed into a single module. In some cases, this module was sealed and encapsulated, making it not repairable or replaceable. Additionally, the Vox service schematic for this guitar provides no "point to point" repair information on these modules. If you find that changing the 9 volt battery that powers the internal effects does not correct a malfunctioning effects circuit, it is likely that the onboard features are permanently inoperative. Complete replacement effects modules have not been available since Whirlpool, the company that purchased the assets of Thomas Organ in 1970, closed the Vox warehouse permanently in 1979.

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