"Dostinex has been approved for the
treatment of hyperprolactinemic disorders, either idiopathic or due to pituitary adenomas (tumors).
Dostinex has been very successful in treating hyperprolactinemia and has been proved much more successful
in doing so than Parlodel (Bromocriptine )"

Dostinex patient information

"Cabergoline (Dostinex) was tolerated
satisfactorily by all our patients. The results have confirmed a high efficacy and a very good tolerability
of Cabergoline (Dostinex) in the treatment of patients with pituitary adenomas. Together with a very
convenient administration, such therapy can provide a very good patient compliance thus should be
considered the first line option in patients with prolactinomas"

Dostinex is a relatively new drug that has been approved for the treatment
of hyperprolactinemic disorders and pituitary tumors. Dostinex decreases
the levels of prolactin, a hormone in your body that when elevated
may cause various medical conditions.

What conditions have been treated successfuly with Dostinex ?

Dostinex is mainly used for treating Hyperprolactinemia and many medical conditions
that are affected by the prolactin hormone. It has been used to treat Parkinson's desease,
Restless Legs Syndrom(RLS), excessive lactation and acromegaly. However you should
consult with your doctor if Dostinex is appropriate for your medical condition.

"These data
indicate that cabergoline is a very effective agent for lowering the prolactin
levels in hyperprolactinemic patients and that it appears to offer considerable
advantage over Bromocriptine in terms of efficacy and tolerability"

"Given
that these patients had advanced disease which makes it difficult to find
significant therapeutic effects, medical therapy with potent dopamine
agonists such as cabergoline (Dostinex) may evolve as a novel therapeutic
option in a subgroup of patients with clinically nonfunctioning tumours
declining operation and radiotherapy"

"Cabergoline
(Dostinex) was shown to be significantly more effective than Bromocriptine
in inducing a complete biochemical response and clinical efficacy
and was better tolerated than Bromocriptine in the majority of patients.
Notable tumour shrinkage until tumour disappearance was observed
during cabergoline treatment in most patients with macroprolactinoma
and it was also proven effective in patients resistant to or with
a poor response to Bromocriptine …
The great efficacy of this compound together with its excellent
tolerability makes this drug the current treatment of choice for
the majority of patients with hyperprolactinaemic disorders"

"These data
indicate that cabergoline is a very effective agent for lowering the prolactin
levels in hyperprolactinemic patients and that it appears to offer considerable
advantage over Bromocriptine in terms of efficacy and tolerability"

"Dostinex has been approved for the
treatment of hyperprolactinemic disorders, either idiopathic or due to pituitary adenomas (tumors).
Dostinex has been very successful in treating hyperprolactinemia and has been proved much more successful
in doing so than Parlodel (Bromocriptine )"

"Six
months of treatment with cabergoline normalized testosterone levels in
most cases, thus restoring and maintaining during treatment the capability
of normal sexual activity in hyperprolactinemic males"

Dostinex has been shown to be very useful in treating Parkinson's Desease

"Cabergoline (Dostinex) significantly improved early morning
motor function, and in spite of increased phase shifts and awakenings,
patients felt significantly more refreshed in the morning during cabergoline
therapy"

We
suggest that cabergoline (Dostinex) is an adequate adjuvant treatment
for Parkinson' disease. There is improvement in motor symptoms (without
substantially increased dyskinesias), reduced severity and duration of
the wearing-off period, and diminished need for levodopa. Cabergoline
can also be useful in the treatment of sleep disturbances associated with
advanced Parkinson's disease such as nocturnal akinesia and dystonia.

"The
efficacy of cabergoline (Dostinex) in Parkinson's Desease patients with
nocturnal disabilities, restless leg syndrome and augmentation has also
been demonstrated. Audits of the clinical efficacy of cabergoline indicate
that it is well-tolerated and has an acceptable side effect profile."

"A
single dose of cabergoline (Dostinex) during hospitalization improves
the patients' compliance and thus the effect of treatment. Cabergoline
(Dostinex)can be used as the drug of first choice for arrest of lactation
after abortion during the second trimester of pregnancy."

"Our conclusion
is that Dostinex is the most effective agent for prevention of the postpartal
lactation given once a day (2 table.) in the first 24 h. post delivery.
We read good effect when the medicine was taken twice daily x 1/2 table.
for 2 days. Dostinex shows vary good compliance and low rate of relapse
of the Lactation"

"In conclusion,
the treatment with dopaminergic drugs such as quinagolide and
cabergoline, significantly increased the efficacy of somatostatin analogs, and
can be used in combined therapy in poorly responsive patients"

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