The Melbourne Renegades bounced back to winning ways in the Big Bash League with a resounding 48-run triumph over the Adelaide Strikers at the Etihad Stadium.

Having seen their perfect record come to an end against the Perth Scorchers last time out, the Renegades strolled to victory to leapfrog Melbourne rivals the Stars and take over at the top of the table.

Their spinners were the key against the Strikers, Muttiah Muralitharan leading the way with three for 18, including dismissing the dangerous duo of Kieron Pollard and Theo Doropoulos in successive deliveries, from his four overs.

Fellow overseas signing Marlon Samuels also claimed three wickets, Adelaide skipper Johan Botha one of the West Indian's victims when he was comfortably caught by opposite number Aaron Finch at cover for a run-a-ball 31.

Michael Klinger (24) and Michael Neser, who made an unbeaten 29 down the order, were the only other Adelaide batsmen to reach double figures as they were bowled out for 107 with nine balls to spare.

The Renegades had earlier worked their way up to 155 for six from their 20 overs despite losing Finch - the tournament's top run-scorer - Michael Hill and Samuels with only 51 on the scoreboard.

Ben Rohrer steadied the ship with 35 from 27 deliveries before he fell to a superb return catch by Pollard, the all-rounder running backwards before diving to take a fine one-handed effort just above the turf.

However, Tom Cooper continued the recovery with a well-made 59, the Dutch international hitting two sixes and the same number of fours in a 46-ball knock that eventually came to an end off the final ball of Melbourne's innings.