Hereditary cardiac disease

The hereditary cardiac disease constitute cardiac diseases in which the genetic background plays a role in pathogenesis. The spectrum of genetic causes spans from monogenic (Mendelian) disorders to genetic risk factor which in epidemiological studies have show to be associated with diseases.

Arbour L et al. (2008) A KCNQ1 V205M missense mutation causes a high rate of long QT syndrome in a First Nations community of northern British Columbia: a community-based approach to understanding the impact.