Homozygous mice. The genetic background of these mice was not specified but included at least some 129S4/SvJae, possibly some 129P2/OlaHsd, and likely had a large contribution from C57BL/6 (based on it being used as wild-type controls for these mice).

Double homozygous mice. The genetic background of these mice was not specified but included at least some 129S4/SvJae and 129P2/OlaHsd and likely included a large contribution from C57BL/6 (based on it being used as wild-type controls for these mice).