MEG-1 (PTPN4), GST-tag

Catalog #: 30015

Size: 20 µg

$375

Species: Human

Host Species: E. coli

MW: 60.3 kDa

Genbank #: NM_002830

Tag(s): N-terminal GST-tag

a.a: 637–926

Background:

PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP acts at junctions between the membrane and the cytoskeleton and has been shown to interact with glutamate receptor delta 2 and epsilon subunits. It also is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation.