Colony Guardians are armed with an Auto Cannon and a tracking Rocket Launcher. Both weapons are fairly powerful and can take down an agent in a few seconds.

While the Rocket Launcher will lock-on and track a target, the missile itself will not avoid obstacles, it is easy to lead it into a pillar or other obstruction, but players should be careful since the rocket has high AoE.

Colony Guardians will fly in a semi-erratic pattern - they can be annoyingly difficult to hit.

As a Mechanical NPC, they are vulnerable to the effects of an EMP Bomb and related debuffs.

Colony Guardias are very resistent and can take a lot of punishment before being destroyed.