Conflict of interest: LL: honoraria for lectures and research support (Biotronik). EMB: research support (Biotronik). WH, JK, JS, and MZ: honoraria for lectures and research support (Biotronik). EV: honoraria for lectures and consulting fees (Biotronik). CM, TD, HS: honoraria for lectures (Biotronik). JVL: previous employment by study sponsor. TL: honoraria for lectures and research support (Biotronik). The other authors have no conflict of interest.