Tim Miller, the director behind Fox’s most lucrative X-Men film to date, Deadpool, will not be returning for the sequel, after all. EW has confirmed the filmmaker has dropped out of Deadpool 2, with additional reports citing creative differences with star Ryan Reynolds.

The studio announced Miller was developing the sequel with Deadpool screenwriters Rhett Reese and Paul Wernick back in April. However, Deadline notes that Miller and Reynolds experienced “mutual creative differences” over the project that eventually resulted in the director’s amicable departure.

Instead, Miller will next develop Fox’s adaptation of the Daniel Suarez novel Influx, expected to be a trilogy of films.

Much like Hugh Jackman with Wolverine and Robert Downey Jr. with Iron Man, Reynolds’s career found new life with Deadpool. The superhero’s first solo film earned $782.6 million worldwide, making it the highest-grossing installment of the X-Men franchise and the second highest-grossing R-rated film of all time (just behind The Passion of the Christ).

While channeling Ferris Bueller’s Day Off, the post-credits scene from Deadpool announced the mutant Cable for the sequel. Production on Deadpool 2 was expected to begin early next year, though now Fox has to find a new director.