Topic Contents

Ectopic Pregnancy: Managing Methotrexate Side Effects

Topic Overview

Methotrexate side effects are more likely to cause problems
when treatment lasts for many months, which is common in cancer and rheumatoid
arthritis treatment. But side effects do occur when methotrexate is given
to end an
ectopic pregnancy.

The most common side
effects of methotrexate treatment for ectopic pregnancy are nausea and
indigestion. Side effects vary from woman to woman. And some women do not
experience any side effects. If you are treated with methotrexate, you will be followed
closely by your doctor.

The suggestions below may
help you manage methotrexate side effects. Tell your doctor about
any symptoms you have during your treatment.

For nausea

Eat small meals more frequently instead of three
large meals daily.

Ask your doctor about
using an antinausea (antiemetic) medicine, such as prochlorperazine or
ondansetron (Zofran) to prevent or reduce nausea.

Rest as much
as possible.

Try to eliminate strong odors from your
surroundings.

Do not use nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and aspirin, which can
increase the risk of stomach irritation.

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