Background: The primary aim of our study was to evaluate the safety and potential toxicity of gemcitabine combined with microbubbles under sonication in inoperable pancreatic cancer patients. The secondary aim was to ...

Choline and betaine are nutrients involved in one-carbon metabolism. Choline is essential for neurodevelopment and brain function. We studied the associations between cognitive function and plasma concentrations of free ...

Introduction: The search for and development of the optimal joint implant include
preclinical testing. Restoration of the individual and natural biomechanics in the hip
joint is a central goal in hip arthroplasty, and ...

Background: Targeted temperature management in cardiac arrest was introduced following evidence of
increased survival from two controlled trials published in 2002. We wanted to investigate whether
the introduction of ...

Background: Incidence and mortality from sudden cardiac arrest is high, making it a
prevalent cause of death. Both incidence and survival rates show great variability
between populations. In order to improve survival ...

The performance of transabdominal ultrasound (US) in chronic pancreatitis (CP) following the advances in US technology made during recent decades has not been explored. Our aim in this prospective study was to evaluate the ...

Background and purpose &mdash; The bone cement market for total knee arthroplasty (TKA) in Norway has been dominated by a few products and distributors. Palacos with gentamicin had a market share exceeding 90% before 2005, ...

Microsatellite instability (MSI) is associated with better prognosis in colorectal cancer (CRC). Elevated microsatellite alterations at selected tetranucleotides (EMAST) is a less-understood form of MSI. Here, we aim to ...

Introduction: Cardiovascular diseases are the leading cause of death worldwide. It can be
defined as a group of interrelated diseases of the heart and blood vessels, including
atherosclerotic cardiovascular diseases. ...

Background and aims: Chronic kidney disease (CKD) may give implications of nutritional status, and studies suggest that patients with CKD have increased risk of malnutrition and nutrition related conditions such as sarcopenia. ...

Introduction and aim: The prevalence of malnutrition in hospital ranges between 10%-60%.
Patients undergoing gastrointestinal surgery are at risk for malnutrition both because of
insufficient food intake pre- and/or ...

Background: Predictors of long-term symptomatic remission are crucial to the successful tailoring of treatment in first episode psychosis. There is lack of studies distinguishing the predictive effects of different social ...

High flow nasal cannula (HFNC) is a relatively new non-invasive ventilation therapy that seems to be well tolerated in children. Recently a marked increase in the use of HFNC has been seen both in paediatric and adult care ...

Purpose: Primary mesenchymal tumors of the pancreas are rare, with leiomyosarcomas the most encountered entities among the pancreatic sarcomas. With few exceptions, single case reports published over the last six decades ...

BACKGROUND: Cancer-associated fibroblasts (CAFs) were shown to be important for tumour progression in head and neck squamous cell carcinomas (HNSCCs). Their heterogeneity and lack of specific markers is increasingly ...