Osomatsu-san, also known as Mr. Osomatsu, is the 2015 TV anime adaptation of the classic Fujio Akatsuka manga, Osomatsu-kun, which was originally serialized in Weekly Shonen Sunday from 1962 to 1969. The franchise was also adapted into an anime by Studio Zero in 1966, then again in 1988 by Studio Pierrot who also handled the 2015 series which was created in honor of Akatsuka’s 80th birthday.

Like Osomatsu-kun, Osomatsu-san follows the comic exploits of the Matsuno sextuplets, only this time they’re around 10 years older and have all become NEETs. The sextuplets are: Osomatsu - the oldest and the leader who loves gambling and playing pachinko; Karamatsu - a ladies’ man and cool dude; Choromatsu - an otaku and generally the voice of reason; Ichimatsu - tired and depressed but loves cats; Jyushimatsu - hyperactive and crazy about baseball with the catchphrase "Muscle muscle, hustle hustle"; and Todomatsu - the youngest and a success with the ladies which earns him the appropriate nickname “Totty.”