Presentation Details

Room: Terra Date: 4 September Time: 11:00:00 Presenter: Li Zhang

Abstract Resume

Background:Although many studies have found the usefulness of aerobic and resistance training in reducing body fat, few study was about maximum lipid oxidation rate (MLOR) intensity
exercise, or has been compared its effect on reducing fat and metabonomics change with resistance training.
Methods:55 obese youth, whose body fat percentage were over 38%, were divided into control group(C, n=15), aerobic training group (AT, n=20）and resistance training group (RT, n=17).
The experiment lasted for 8 weeks. Subjects were submitted to different physical training and the same diet restriction during 1st -4thweek and no intervention during 5th-8th week in order to see the
sustainability of training effect. The C group didn’t receive extra exercise intervention besides their normal life activity. The AT group was trained by aerobic exercise with intensity of the MLOR
point. RT group were trained by resistance strength training. The exercise time was 1.5 hours/day and 6 days/week. The daily calory was based on subject’s personal RMR. Parameters including body
composition by DEXA and blood metabonomics by NMR were measured pre-training and at the end of the 4th and the 8th week.
Results:(1) At the end of 4th week, when compared AT and RT groups with C group, significant differences (p<0.001) were observed in: BMI (C 0.433±2.40% vs. AT -8.22±1.95% and RT
-7.72±1.70%), total fat mass (C -2.47±9.28% vs. AT -19.89±7.69% and RT -18.36±6.18%), arm fat mass (C -4.51±13.8% vs. AT -22.04±9.36% and RT -16.30±8.45%), leg fat mass (C -3.65±7.73% vs. AT
-8.78±27.22% and RT -15.80±4.63%), trunk fat mass (C -1.48±12.8% vs. AT -21.97±9.68% and RT -20.04±9.03%), total muscle mass (C 1.54±3.03% vs. AT -2.28±2.16% and RT -1.77±3.77%). When compared AT
group with RT group, we only found significant difference in total muscle mass (p=0.004). (2) When compared the change between the 8th week and the 4th week in AT group, significant
differences(p<0.05) were observed in: total fat mass (-3.89±6.79%) and trunk fat mass (-5.73±7.86%). In RT group, significant differences were observed in: arm fat mass (-5.79±10.63%) and leg fat mass
(-4.06±6.45%). However, no significant differences was found between AT and RT groups. (3) Metabolic profiles of 4th week and 8th week could be distinguished from each other and 19 metabolites were
identified by OPLS-DA, which are characteristically manifested mainly in lipid, energy and creatine metabolism. Inflammatory marker NAC also has changed. However, the scores plot of the PCA model
showed a differentiation tendency of metabolic profiles by training but return by detraining.
Conclusions:Four weeks of resistance strength exercise and maximum lipid oxidation rate intensity exercise combine proper diet restriction showed satisfied effect on reducing body
fat. And the metabolic profile was also been significantly affected, but resumed by one month of detraining. Resistance exercise showed better benefit of protecting muscle than aerobic exercise. The
fat mass reduces faster in body parts that not participate in exercise directly than body parts that directly participate in exercise.