Arsenal were not expecting to see the 21-year-old come off the bench and will now lament that fact after he took a kick to his fragile ankles from German counterpart Sidney Sam.

Wilshere remains hopeful about being fit for Southampton but Wenger has regularly erred on the side of caution with Wilshere's fitness so far this season and may continue to do so against Southampton.

The young England and Arsenal star has struggled with injury over the last two seasons, specifically with regards to his ankle. Ankle fractures in the past have caused him to miss large chunks of Arsenal's seasons in the past, stalling his development as a result.

This is not the first time Wenger has been at odds with Hodgson after the England manager played Wilshere for a full 90 minutes against Brazil despite Wenger's pleas to not do so.

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