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As you know, Wise Disk Cleaner and Wise Care 365 are auto-cleaner, if some files cannot be deleted, they could be protected by other programs or they are used now.For security reason, Wise Disk Cleaner doesn't force delete these kind files.If you are sure these files can delete safely, you can try Wise Force Deleter.

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I saw these invalid shortcuts stored in Windows/winsxs, the possible reason is that wise disk cleaner doesn't have enought permision to delete them or these files are protected by system, wise disk cleaner cannot delete them.You can try to delete them manyally.