Nix, who selected Florida State quarterback E.J. Manuel with a first-round selection in the NFL draft last month, held the GM reins since the final day of 2009. He joined the club as a scout in 1993.

"I've made this decision to step away from the General Manager's position because I feel it is the right time," Nix said in a statement released by the team.

"By the 'right time,' I mean I think we have a good young roster, an excellent head coach with a good staff, and it's time to let someone else handle these responsibilities and move forward together. Timing is the main thing, but there are other benefits as well. This job is very demanding with a 24-7 schedule of responsibilities.

"This new position will enable me to spend more time with my family. I appreciate the opportunity given to me by Mr. Wilson and Russ and I'm fortunate to step away from the job and still remain a part of the team."

If the Bills blossom with their current nucleus, Nix's fingerprints will be included. His first-round picks included running back C.J. Spiller, defensive tackle Marcell Dareus and cornerback Stephon Gilmore. He also signed Mario Williams as a free agent last year, luring the defensive end with a six-year deal could be worth $100 million and was the richest ever for a defensive player.

"I feel strongly that the team is on the right course for success," Nix said. "We have some excellent talent on our team and Coach Marrone and his staff are doing a terrific job in leading and teaching the players we have on our roster. I was very impressed with the 24 rookies we had in this past weekend and I'm very excited about the upcoming season. I think this is going to be an exciting time for our team and our fans."

In March, Nix and Tampa Bay Buccaneers GM Mark Dominik were targeted by two pranksters who recorded their conversation, which was exposed on Deadspin.com.