Combat relies on three options - light attacks, heavy attacks, and grabs, mapped to one button apiece - but doesn't ask players to memorize long combo strings. Another form of attack is the lunge, which allows Wolverine to quickly close the distance between him and an enemy. Not only can Wolverine dispatch of enemies via his variety of attacks, he can also use the environment to his advantage, like impaling foes on spikes. Due to the physics system, when Wolverine is shot or stabbed, which removes parts of his flesh and clothes, his injuries will heal in real-time, allowing you to see his muscles and skin grow back. During the course of combat, Wolverine's rage meter begins to build up, and when full allows him to unleash more deadly, devastating attacks. His claws will also glimmer red when he is in berserker mode.

X-Men Origins: Wolverine needs a Core 2 Duo E6300 1.86GHz or Athlon 64 X2 Dual Core 5200+ processor coupled with a GeForce 8800 GS to run system requirements at recommended high graphics settings. This will return around 60FPS at 1080p screen res. System memory required for X-Men Origins: Wolverine is 2 GB performance memory. Your PC needs 1 GB system memory as well for min. Your GPU is expected to be able to deliver DirectX 9. Recommended needs around a 11 year old PC to run.