Polyclonal Antibody to GFRα-1 (IN)

PSC-1133-C020

20 µg

87.00 USD

PSC-1133-C100

100 µg

358.00 USD

Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerve system. Physiological responses to GDNF require the presence of a novel glycosyl-phosphatidylinositol linked protein GDNFRα, which is a cell surface receptor for GDNF [1,2]. The cDNAs encoding GDNFRα from human, rat, chicken and mouse have been cloned [1-5]. GDNFRα was also termed Ret ligand 1 (RETL1) or TGF-β-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFRα [5-7].