Micro lesion effect of the globus pallidus internus with deep brain stimulation in Parkinson’s...
Wang, Yi; Li, Peng; Gong, FeiLong; Gao, Yuan; Xu, Yang; Wang, Wei
2017-07-28 00:00:00
Acta Neurochir (2017) 159:1727–1731 DOI 10.1007/s00701-017-3271-4 ORIGINAL ARTICLE - FUNCTIONAL Micro lesion effect of the globus pallidus internus with deep brain stimulation in Parkinson’s disease patients 1 1 1 1 1 1 Yi Wang & Peng Li & FeiLong Gong & Yuan Gao & Yang Y. Xu & Wei Wang Received: 24 April 2017 /Accepted: 10 July 2017 /Published online: 28 July 2017 Springer-Verlag GmbH Austria 2017 Abstract on medication. Compared with the preoperative state, the Background The micro-lesion effect (MLE) has been ob- UPDRSIII score, off time and severe dyskinesia time had served in many Parkinson’s disease (PD) patients after deep improved postoperatively. brain stimulation (DBS) surgery. For subthalamic nucleus Conclusions The MLE of GPi is a predictor of PD patients (STN) stimulation, the MLE has been reported as a predictor who would benefit from DBS in the long term. Medication of the long-term efficacy of DBS. However, the research on may have some conflicting effects on the MLE. The exact the MLE in the globus pallidus internus (GPi) is insufficient. mechanism of the MLE requires further exploration. In this report, we conducted a study of the correlation between the MLE and improvement of GPi DBS. . .
http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.pngActa NeurochirurgicaSpringer Journalshttp://www.deepdyve.com/lp/springer-journals/micro-lesion-effect-of-the-globus-pallidus-internus-with-deep-brain-mNaTHwEgXP