VIROVEK'S

BAC-TO-AAV TECHNOLOGY

FOR LARGE SCALE AAV PRODUCTION

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Safety and Storage

AAV Safety

According to guidelines from the National Institutes of Health (NIH), AAV vectors are considered risk group 1 agents that are not associated with disease in healthy adult humans. Our recombinant AAV vectors can be handled in a Biosafety Level 1 (BSL-1) environment.

AAV Vector Storage and Handling

For short-term storage, AAV vectors are stable at room temperature and 4°C. You may elect to have us ship your vectors on Ice Packs at 4°C.

For long-term storage, keep AAV vectors at -80°C. Do NOT store at -20°C. Research suggests that long-term storage at -20°C is not necessarily effective, and may result in decreased transduction efficiency of the virus when it is removed from storage, thawed, and used. You may elect to have us ship your vectors on Dry Ice at -80°C.

Additional recommendations for AAV handling:

AAV can be thawed at room temperature.

Please avoid unnecessary freeze-thawing of AAV vectors, as excessive freeze-thawing cycles may result in a significant decrease in titer and loss of biological activity.

Safety Data Sheet

Our AAV vectors are not considered Hazardous Materials by Federal OSHA or CalOSHA, and are not legally required to come with a Safety Data Sheet (SDS). However, we would like to provide relevant information on recommended handling practices and safety. This data sheet may be helpful if you anticipate difficulties with product identification in international shipping requirements, or within your organization. Please click on the title below to view the document.