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Lady Deathstrike began her super villain career as an ordinary human, but eventually the advanced modifications to her body reconfigured her into a cyborg warrior, giving her an Adamantium-sheathed skeleton and long Adamantium claws in the place of fingers.

Eventually she conceived a misguided quest to restore the honor of her abusive mad scientist father, who in fact represented the impetus of her instability. The bulk of her animosity was directed at Wolverine, due to his own Adamantium skeleton, because she believed that the alloy-fusing process had been stolen from her father.

Lady Deathstrike follows a kind of Samurai code. Her logic system is heavily based in honor and discipline, though most of the time her perspective is set askew by her psychological instabilities. After a string of numerous defeats, she believes her honor to be compromised, which further accelerates her madness, and which makes her somewhat sympathetic despite her bloodlust and assassin ways.