Lamivudine Tablets (Lamivir HBV and Lamivir) - Product Information

Lamivudine tablets (Lamivir HBV and Lamivir) is used for the treatment of chronic hepatitis B virus infection associated with evidence of hepatitis B viral replication and active liver inflammation. This medicine is also used along with other medicines to treat human immunodeficiency virus (HIV) infection.

Generic Epivir and Generic Epivir HBV Tablets (Lamivir HBV and Lamivir) is used to treat hepatitis B infection. It is also used along with other medicines to treat human immunodeficiency virus (HIV) infection.

Lamivudine is an antiviral agent which is highly active against hepatitis B virus.

Lamivudine Tablets and Lamivudine HBV Dosage

The recommended oral dose of Lamivudine HBV(Generic Epivir HBV) for treatment of chronic hepatitis B in adults is 100 mg once daily. Safety and effectiveness of treatment of Lamivir- HBV beyond 1 year have not been established and the optimum duration of treatment is not known.

The recommended oral dose of Lamivudine tablets (Generic Epivir) in HIV-1 infected adults and adolescents greater than 16 years of age is 300 mg daily, administered as either Lamivir 150 mg twice daily or 300 mg once daily, in combination with other antiretroviral agents.
If Lamivudine tablets are administered to a patient infected with HIV-1 and HBV, the dosage indicated for HIV-1 therapy must be used as part of an appropriate combination regimen.

Lamivir HBV and Lamivir Contraindications

Lamivir HBV and Lamivir tablets are contraindicated in patients with a hypersensitivity to Lamivudine or any inactive ingredient present in tablets.

Warnings and Precautions

Co-infected HIV-1/HBV Patients: Emergence of Lamivudine resistant HBV variants associated with lamivudine-containing antiretroviral regimens has been reported.
Emtricitabine-containing products should not be administered concomitantly with Lamivudine containing products.
Hepatic decompensation, some fatal, has occurred in HIV-1/HCV co-infected patients receiving interferon and Ribavirin based regimens.
Monitor for treatment associated toxicities. Discontinue Lamivir HBV and Lamivir as medically appropriate and consider dose reduction or discontinuation of interferon alfa, Ribavirin, or both.
Pancreatitis: Use with caution in pediatric patients with a history of pancreatitis or other significant risk factors for pancreatitis. Discontinue treatment as clinically appropriate.
Immune reconstitution syndrome and redistribution/accumulation of body fat have been reported in patients treated with combination antiretroviral therapy.
In patients with moderate to severe renal impairment, serum Lamivudine concentrations (AUC) are increased due to decreased renal clearance, therefore the dose should be reduced for patients with a creatinine clearance of less than 50 mL/minute.
Cases of lactic acidosis, usually associated with severe hepatomegaly and hepatic steatosis, have been reported with the use of combination nucleoside analogue therapy in patients with HIV.

Lamivudine Side Effects

The most common reported Lamivudine side effects with incidence greater than or equal to 15% in adults were headache, nausea, malaise and fatigue, nasal signs and symptoms, diarrhea, and cough.

Please inform your doctor in case any of the symptoms listed below are severe or do not go away:

diarrhea

headache

fatigue

chills

nausea

vomiting

loss of appetite

dizziness

trouble sleeping

depression

stuffy nose

cough

In case you experience any of the following symptoms listed below please inform your doctor immediately:

rash

stomach pain

vomiting (in children)

nausea (in children)

fever

muscle pain

numbness, tingling, or burning in the fingers or toes

Lamivudine Overdosage

Currently is no known antidote for Lamivudine. In case overdose occurs, the patient should be monitored, and standard supportive treatment utilized, as required.

Due to the fact that a negligible amount of Lamivudine was removed via (4-hour) hemodialysis, continuous ambulatory peritoneal dialysis, and automated peritoneal dialysis, it is not known if continuous hemodialysis would provide clinical benefit in a Lamivudine overdose event.

Lamivudine During Pregnancy

Lamivudine has been classified by the US FDA as Pregnancy Category C. There are no adequate and well-controlled trials of Lamivudine- HBV or Lamivudine in pregnant women.

Due to the fact that animal reproduction studies are not always predictive of human response, Lamivir- HBV and Lamivir should be used during pregnancy only if the potential benefits outweigh the potential risks to the fetus.
Do not use this medicine without your doctor's consent in case you are pregnant.

Nursing Considerations

Lamivudine is excreted in human milk. Since there exists a potential for serious adverse reactions in nursing infants, a decision should be made to discontinue Lamivir- HBV taking into consideration the importance of continued hepatitis B therapy to the mother and the known benefits of breastfeeding.
Do not use this medication without telling your doctor if you are breast-feeding a baby.

Buy Lamivudine Pills Online at Only $0.56 per Pill

You can buy Generic Epivir HBV and Generic Epivir online from Clear Sky Pharmacy at a cheap price. Lamivir- HBV 100 mg and Lamivir 150 mg pills, manufactured by Cipla Ltd. , India are supplied in a blister strip of 10 tablets. The 100 mg Lamivudine HBV tablets as well as the 150 mg Lamivudine tablets cost only $0.56 per unit when you place an order for 360 tablets.

Disclaimer

The above information is provided to the best of our knowledge and in good faith, it is without a warrant of any kind, expressed or implied.

We focus on premium quality drugs at the lowest possible prices and we guarantee that you will always receive the same brand name exactly as presented on our site.
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