The association between volume and age across the lifespan in entorhinal cortex and…

Figure 3

The association between volume and age across the lifespan in entorhinal cortex and hippocampal subfields. All volumes are adjusted for intracranial volume (ICV; see text for details). The associations with age in the entorhinal cortex [Volumei = 786.06 – 9.65(Agei) + 0.08(Agei2)] and CA3-dentate gyrus [Volumei = 308.02 – 2.64(Agei) + 0.02(Agei2)] were quadratic (both p < 0.01), whereas the effect in CA1–2 was linear [p < 0.001; Volumei = 351.76 – 0.63(Agei)]. There were no age differences in subiculum volume (p = 0.17). Gray circles represent data points that were winsorized.