Oddsmaker Nick Kalikas from BetOnFighting.com, quickly set the line on the fight, opening with dos Santos as a -240 favorite, with the comeback on Overeem at +190.

“I was very impressed with Overeem’s performance against Brock. I think we might see his domination of Lesnar impact the betting line early, so wouldn’t be shocked if we see the initial line drop slightly,” Kalikas told MMAWeekly.com when opening the line.

“As we get closer to fight day, I think we might see it climb back up some. Should be a great fight, but make no mistake JDS is the rightful solid favorite heading in. I firmly believe he’s currently the best heavyweight in the world.”

Opening it up to fans with our MMAWeekly.com Reader’s Poll, you guys seemed to think otherwise, at least early on. After several thousand votes were cast, it was close, but Overeem was the outright favorite.

The consensus centered on how the fight would end… by knockout or TKO.

After the poll closed, it was Overeem as the favorite with 48 percent of you saying he would win by KO or TKO, while 43 percent thought the dos Santos would be the fighter with the heavier hands when they finally square off.

Considering the early returns, this will surely be one of the most anticipated heavyweight title fights in some time.