Hilary Swank, Matt Dillon, Jamie Foxx, and Queen Latifah joined sports icons like Peyton Manning for the largest fundraiser for Down Syndrome in the nation, which happened to be held in downtown Denver.

Dixon walked alongside Queen Latifah who spoke about the importance of the Global Down Syndrome's cause.

Frank Stephens was awarded the Quincy Jones Exceptional Advocacy Award. He is an active spokesman for the Global Down Syndrome Foundation and a member of the Board of Directors of Special Olympics Virginia.

President Obama described Stephens as a man who “writes eloquently about the pain and exclusion when others don’t accept you or treat you with the respect every human being deserves.”

For the fashion show newcomers, model Amanda Booth, joined by her son Micah, offered some advice to the models.

Peyton Manning didn't walk the red carpet - but he was all smiles on the runway.

Actor and Global Down Syndrome Foundation spokesperson John C. McGinley, who has a son with Down Syndrome said he's excited that the event keeps growing.

To date, the event has raised more than $12 million and attracted 1,200 guests.

The night was filled with touching moments you can see in the gallery below:

To hear from this year's ambassador, Louie Rotella IV, watch the video below: