Product Specification

EIA (1:4,000)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.

Formulation:

Liquid. Contains 0.1% sodium azide.

Handling:

Avoid freeze/thaw cycles.

Shipping:

Shipped on Blue Ice

Long Term Storage:

-20°C

Scientific Background:

Cyclic GMP (cGMP), which has been shown to be present at levels typically 10-100 fold lower than cAMP, is formed by the action of the enzyme guanylate cyclase on GTP. Some hormones, such as Acetylcholine, Insulin, and Oxytocin, as well as certain other chemicals like Serotonin and Histamine cause an increase in cGMP levels. Stimulators of guanylate cyclase such as the vasodilators nitroprusside, nitroglycerin, sodium nitrate, and nitric oxide (NO) also stimulate cGMP levels.