Manningham potentially could miss all of training camp and start the regular season on the PUP list, meaning he would miss the first six games.

The 49ers potentially could activate Williams and Hunter before the final cuts. Still, there’s a chance those two players will miss most of training camp and most of the pre season.

With Williams and Hunter on the shelf for now, do you expect LaMichael James to win the No.2 running back job this season, and Quinton Patton or A.J. Jenkins or someone else to win the No.2 wide receiver job?