Santin's main title was in the Italian Formula Three Championship in 1984, in which he drove a Ralt-Alfa to four wins. From 1985 to 1988, Santin drove in the European Formula 3000 championship for many teams (Sanremo in 1985; Coloni, Sanremo, Lola Sport, Eddie Jordan Racing and Formula Team in 1986; Genoa in 1987 and Eddie Jordan Racing in 1988), without great results. His better results were two sixth places in Silverstone and Vallelunga in 1986, driving a Lola T86/50. His best start position was in Mugello in 1986, when he started from the second position, also driving a Lola T86/50.

Santin has also raced in prototypes championships and drove in the 1989 Le Mans 24 Hours with Pascal Fabre. Nowadays, he attends historical Formula 3 events in Italy.