We are interested in the mechanisms of the ribosome function. The ribosome is a central component of cell metabolism, translating genetic code and synthesizing proteins in all living organism. The ribosome is an extremely complex and highly dynamic machine. Our research is focused on the mechanics of ribosome movement along mRNA during protein synthesis. Movement of ribosomes along mRNA is essential attribute of protein synthesis in all organisms and often used to regulate protein expression.

Ermolenko DN, Richardson JM, Makhatadze GI. Noncharged amino acid residues at the solvent-exposed positions in the middle and at the C terminus of the alpha-helix have the same helical propensity. Protein Sci. 2003 Jun; 12(6):1169-76.