Welcome to Vaxign: Vaccine Design!

Vaxign (Vaccine Design) is a vaccine target prediction and analysis system based on the principle of reverse vaccinology. Two programs exist in Vaxign: (1) Vaxign Query: provide precomputed Vaxign results for users to explore, and (2) Dynamic Vaxign Analysis: allow sequence input and dynamic Vaxign execution and result visualization.

1. Vaxign Query:

This program allows users to search precomputed Vaxign results for > 350 genomes. A user can either select a genome(s) for all possible vaccine targets based on desired parameters, or query a protein sequence(s) from a genome to find possible vaccine vaccine target(s):

Select a Genome(s), Query a Protein (Optional), and Set up Parameters (Optional)

Select a Genome Group (Required)

Select a Genome (Required)

Sequence ID(s)

(One ID per line, or use comma, tab-delimited format)
Or load IDs from file

Tips: To select (or unselect) individual genomes, press Ctrl key and then select; For genome selection in continuous order, you can also use Shift key.

2. Dynamic Vaxign Analysis:

This program allows users to input a protein sequence(s) and set up parameters. The Vaxign web server will dynamically calculate the possibilities of using the protein(s) as vaccine target(s) using the automatic Vaxign pipeline. It is noted that lengthy computational time may be expected.