With EPA since 1974 and at the EPA Office of Pollution Prevention and Toxics (OPPT) or its precursors since 1979. Previously EPA observer to the NRC Numerical Data Advisory Board, EPA representative to the interagency Integrated Data Users Group and organizer and chair of the former EPA Data Users Group. Participated in the initial development of the Biotechnology Program operating under the Toxic Substance Control Act (TSCA) at EPA and part of that program since 1984. In addition to participating in team assessments of industrial and commercial microbes that fall within the purview of that law, helped develop policies for regulating these organisms. Currently participate in intra- and interagency working groups developing guidance for microbial risk assessment. Part of a group coordinating EPA’s intra- and interagency biofuels related activities. EPA representative to the Interagency Metabolic Engineering Working Group that helps coordinate research support for metabolic engineering throughout the US government. Member of the sub-working group on microorganisms of the OECD Working Group on Harmonization of Regulatory Oversight in Biotechnology.