The software has its preloaded tools acting as close to them as they perceive it.IE: I use the basic mechanical pencil for sketching out ideas.The increasing the size for a darkening an area or using the darker pencil tool.

Then for "inking" using the basic g-pen settings works for me. With using bucket tool or market> milli/felt pen to fill in blacks.I havent played around with thier screen tones. But I assume its kinda like photoshop where you just fill/select an area an apply the tones to them.

I use MS5 But not the expert version :/From what I can see it is very much like paint tool Sai (never used Sai so I'm not too sure), but with some extra features specifically for Manga. Like screen tones, panel tools and things like that :3

I use Manga Studio 5 ex. I had the normal version originally but I loved it so much I upgraded. The upgraded version has a grouping funtion called "Story" where you can keep all the pages for one story together. Super convienient.

I really love the tools too and it's very customization. I use to use Sai but I completely switched over to Manga Studio.It also comes with tons of comic tools (even screentones and bubbles). It's just really convenient. I'm in love with it and tend to preach how amazing it is to people. ///