Newest reported 2001 Nissan Frontier problems

The EGR valve can become clogged with carbon, which causes the Check Engine Light to illuminate. This can result in moderate to severe misfires on acceleration and the EGR valve and passages will need to be cleaned.

The fuel injectors can fail and cause drivability problems. Often there is no Check Engine light and the failures can be caused by corrosion of the connector, clogging beyond the point of cleaning, and/or internal failures.