From Interstate 70, take Highway 19 (Exit 175) south 15 miles to Hermann. Cross the Missouri River bridge and continue south on 19 through town. Turn left (east) on Highway H, then left on Bayer Road. Look for Stone Haus B&B on the right.

Traveling west on Highway 100, turn left on Gutenberg Street at the Tin Mill Brewery. Continue on Gutenberg until it becomes Bayer Road. Look for Stone Haus B&B on the left, just before the Highway H intersection.