ARGENT Cell Signaling Regulation Kits from ARIAD—Now Available from Clontech

Clontech is the exclusive provider of iDimerize products—homodimerization and heterodimerization systems and ligands (e.g. AP20187, AP21967) which were previously provided by ARIAD under the brand name ARGENT. The tables below show the iDimerize nomenclature and the equivalent ARGENT products and components.

D/D Solubilizer (A different molecule which is functionally equivalent to AP21998)

Dimerization Domains

The amino acid sequences of the FV and FV' domains are identical; however there are significant differences at the nucleotide sequence level which reduce the potential for recombination between the repeating domain within the pC4M-FV2E plasmid (pHom-Mem1). The same is true of the F and F' domains within pC4M-FV2E (pHet-Mem1). Clontech does not distinguish between the two when referring to the dimerization domain.