I'm running 13.8.1.38 on Windows 10 (Fresh install) on a 6700K with a GTX 1070 and 32 gigs of RAM on a blisteringly fast NVMe drive. I HAD a GTX 670 a few days ago with the same problem so I can't really point at the graphics card drivers.

What's happening is when I open Ae with the default setup of the comp window being on a separate monitor it then starts up white in the comp window and nothing displays. Dragging the comp window back to the main Ae window makes it duplicate the timeline (not clickable, just visual) in itself (Think drag trails on a broken Windows 98 crash). I close Ae with the windows docked all in one screen, open it up again, and all is well. I'll drag the comp window back to the other monitor and it carries on working. I'm also finding that the Ae process doesn't die as quickly as I would expect, it chills there for up to five minutes some times. I have to manually stop it before Ae will open again.

I'm running Windows 10 in my freelance studio and my interface panels are usually scattered across four monitors and I haven't experienced this issue. Although, I don't think any of my layouts are very similar to yours. If I remember, the next time I'm in there without a looming deadline, I'll give it a poke.

In the meantime, it wouldn't hurt to file a bug so Adobe knows about the issue.

Thanks Szalam The more I work the more it's feeling like a bad windows install honestly. I'm getting mild display glitches every now and then. I might test on a different drive with a new OS and see if I get different results... too many variables right now.

Tried a few different builds of Windows and I'm getting the same results. So now I suspect either hardware or mildly incompatible graphics drivers (even though I have the latest). I've even swapped out my motherboard (for the same model) because it had bad tracks on the back.

So either it's my 1070 or it'll solve itself later with future driver updates.