A third person has been confirmed dead on Monday, after a shocking vehicle collision on an isolated stretch of road in Western Australia.

According to a police spokesperson, on Sunday afternoon a utility vehicle crashed into a mini-bus carrying a number of tourists along the Indian Ocean Drive around 30 km north of the township of Lancelin.

The driver of the utility vehicle died at the scene along with another man on board the mini-bus, while the third person succumb to his injuries after being taken to hospital.

With nine people still recovering in hospital, it took emergency responders "some time" to free those trapped from the wreckage before seven ambulances and two helicopters were able to transport the survivors for treatment.

Local media outlet, the Australian Broadcasting Corporation, has reported that at least three survivors remain in a serious condition.

Considered to be one of the state's most notorious stretches of road, the Indian Ocean Drive witnessed six people losing their lives on the 60 km route in 2017.