Why do you recommend that biological parents provide DNA samples?

To help our clinical experts interpret your child’s results, we strongly recommend that both biological parents also provide DNA samples. Analyzing the parents’ DNA can help confirm or rule out a positive result if a variant (or change) is detected in the child’s DNA. While a false positive is very unlikely, this simple step may help prevent unnecessary worry for you and your family.

Providing a sample is simple! Every DNA sample for Sema4 Natalis is collected at home through a gentle cheek swab. We recommend doing this at the same time you collect your child’s DNA sample.

If you order Natalis through your pediatrician, a parent can provide their sample at the healthcare provider’s office at the same time that the child does.

If you would like to provide a DNA sample, here are a few important things to know:

When you order Sema4 Natalis, please indicate which biological parent(s) will provide a sample

We will only analyze your sample if your child screens positive

If your DNA sample is analyzed, Sema4 will include the results in a comprehensive report that will be shared with you and your child’s doctor. You will not receive a separate report for the analysis of your sample