What are the effects of cannabis?

The effects experienced by the cannabis user are variable and will depend upon the dose, method of administration, prior experience, any concurrent drug use, personal expectations, mood state and the social environment in which the drug is used.

Effects of cannabis include:

an altered state of consciousness. The user may feel “high”, very happy, euphoric, relaxed, sociable and uninhibited.

distorted perceptions of time and space. The user may feel more sensitive to things around them, and may also experience a more vivid sense of taste, sight, smell and hearing.

impaired coordination and concentration, making activities such as driving a car or operating machinery difficult and dangerous.

negative experiences, such as anxiousness, panic, self-consciousness and paranoid thoughts.

People who use large quantities of cannabis may become sedated or disoriented and may experience toxic psychosis – not knowing who they are, where they are, or what time it is. High doses may also cause fluctuating emotions, fragmentary thoughts, paranoia, panic attacks, hallucinations and feelings of unreality.

The effects of cannabis are felt within minutes, reach their peak in 10 to 30 minutes, and may linger for two or three hours. THC is highly lipid soluble and can be stored in fat cells potentially for several months. The stored THC is released very slowly, and unevenly, back into the bloodstream.

Medical uses

While cannabis remains a Schedule 1 substance, research has resulted in development and marketing of dronabinol and nabilone which are synthetic cannabinoid products.

Marinol (dronabinol) is used for the control of nausea and vomiting caused by chemotherapeutic agents used in the treatment of cancer and to stimulate appetite in AIDS patients.

Cesamet (nabilone) is used for the control of nausea and vomiting caused by chemotherapeutic agents used in the treatment of cancer.

Medical Cannabis (Medical Marijuana)

There are eight medical conditions for which patients can use cannabis:

CBD Oil or Realm Oil

Several states are now considering or have passed bills to allow legalization of medical marijuana oil (CBD oil or Realm Oil) for intractable seizures in children with Dravet Syndrome. These children can suffer 40 or more seizures per day; the seizures are often prolonged in length. The oil is made a from a special strain of marijuana called “Charlotte’s Web” that has extremely low levels of tetrahydrocannabinol (THC), the psychoactive ingredient in marijuana that leads to the “high”. However, the strain has elevated levels of cannabidiol, or CBD, a non-psychoactive component that has been shown to have a number of therapeutic benefits, including those that limit seizure activity. The oil is taken in an oral liquid form, not smoked like traditional marijuana. News media has showcased several families from states that do not allow the CBD oil. These families have moved to Colorado from their home states to access the oil legally for their children who suffer from the debilitating seizures. Legislation is currently under review in several states to allow the oil for children with this debilitating seizure condition.

That being said, it is unlikely that the federal government is interested in pursuing individuals complying with state-mandated regulations surrounding legalized cannabis for recreational use, although the CSA law still gives them authority to do so.

The Department of Justice (DOJ) has attempted to clarify this issue. On August 29, 2013, the DOJ issued guidance to Federal prosecutors concerning marijuana enforcement under the CSA. The DOJ is focused on priorities, such as:

Preventing the distribution to minors

Preventing revenues from sale of marijuana towards criminal activity

Preventing diversion of marijuana from states where it is legal to states where it is not legal

Preventing state-legalized marijuana from being a cover for other illegal drugs or activity

Prevent violence and guns in the cultivation and distribution of marijuana

Prevent drugged driving and other public health issues

Prevent the use of public land for marijuana cultivation

Preventing marijuana possession or use on federal property

Additional states may undertake or pursue citizen petitions in the future to legalize the recreational use of cannabis. Reportedly there may be initiatives for full commercial legalization on the ballot in California and Maine in 2016. According to the Brookings Institute, Presidential years bring out an electorate more favorable to cannabis legalization than the off-year electorate. Other states pursuing legalization may include Arizona, Nevada, Massachusetts, Montana, Rhode Island, and Vermont. Maine and Michigan citizen voters have also passed legalization of cannabis for recreational use, but state law will likely override these voter referendums; only medical marijuana is currently legal according to state law in these states.

A majority of Americans support legalization of marijuana – 52 percent pro versus 45 percent con – according to findings from a Pew Research Center survey in March 2013. Support for marijuana legalization has increased dramatically since 2010, by 11 percentage points.

Specific city and county laws have been enacted to regulate how citizens and tourists may possess and consume marijuana. Penalties exist for driving while under the influence of marijuana. Someone driving under the influence of marijuana is considered impaired in both Colorado and Washington when five nanograms per milliliter (ng/mL) of blood or more of active THC is detected.

Do not use cannabis if you are pregnant or could become pregnant. There is some evidence that women who smoke cannabis during the time of conception or while pregnant may increase the risk of their child being born with birth defects. Pregnant women who continue to smoke cannabis are probably at greater risk of giving birth to low birthweight babies.