During the Totality Crisis in 2381, a number of Starfleet vessels suffered from warp core breaches. The matter was kept under a veil of secrecy and led to the Enterprise-E being sent a message from Starfleet Command to drop out of warp at Kuiper 575 in order for both the Enterprise-E and the USS Titan to be escorted to Jupiter Station. At the time on Stardate 58562.5, multiple Starfleet ships suffered from catastrophic warp core failiures leading to the deaths of thousands - some due to the actual destruction whilst others were lost when the major research platforms suffered from the loss of their shields which led to Jupiter's deadly radiation killing them. (TOSnovel: Captain's Glory)

It is unclear whether the 22nd century station existed into the 24th century, or whether a later replacement facility shared the same designation.