Filmmaker Judd Apatow gave a rare standup performance in Los Angeles Saturday night, using the opportunity to spend most of his routine zinging President Trump and his family.

Mr. Apatow, an outspoken critic of Mr. Trump, had joined Pete Holmes at the Regent Theater to promote their HBO series “Crashing.” Mr. Apatow started off his set by saying the president’s election victory made him feel like “a person about to get raped, but I didn’t know how bad it would be,” The Daily Beast reported.

Mr. Apatow said now that Mr. Trump is president, “I feel like I’ve just been raped and I just don’t know if I’m going to get murdered.”

He then turned his sights on the first family, joking that first lady Melania Trump is deliberately delaying her move to the White House in order to avoid her husband.

“Every day she’s not in the White House is a day she’s not getting f—ed by Donald Trump,” Mr. Apatow said. “Wouldn’t you stay away?”

“I mean, think about it: Hillary Clinton didn’t move out of the White House and her husband got a blow job in it,” he said.

Mr. Apatow even included a few jokes about 10-year-old Barron Trump, The Daily Beast reported.

“He f—ing gets it,” the comedian said.

“You ever see the look on his face when Trump’s talking?” he asked. “People are like, ‘Is there something wrong with him?’ No! He knows his dad’s a f—ing asshole!”

Mr. Apatow told The Hollywood Reporter during an interview Monday that he thinks it’s important for people who disagree with the president to speak out.

“We have a president that fights against sane gun laws, Planned Parenthood, our current health care system, environmental protection, banking regulation and it looks like he wants to defund PBS and the national endowment for the arts,” he said.

“He is caught lying on a daily basis and is caught up in a massive amount of conflicts of interest,” he added. “I think all of us are at risk as a result of these policies and by using humor or any other weapon we have, people who disagree should speak up.”