arsenical

arsenical

[ahr-sen´ĭ-k'l]

1. pertaining to arsenic.

2. a compound containing arsenic; arsenicals were once widely used in medicine, but have now mostly been replaced by antibiotics. However, some are still used to treat infectious diseases, especially those caused by protozoa, as well as skin disorders and blood dyscrasias; they must be administered with caution because of their toxicity. All arsenicals are toxic to humans and some are carcinogenic. See also arsenic poisoning.

ar·sen·i·cal

(ar-sen'i-kăl),

1. A drug or agent, the effect of which depends on its arsenic content.

2. Denoting or containing arsenic.

arsenical

(är-sĕn′ĭ-kəl)

adj.

Of or containing arsenic.

n.

A drug or preparation containing arsenic.

ar·sen·i·cal

(ahr-sen'i-kăl)

1. Denoting or containing arsenic.

2. A drug or agent, the effect of which depends on its arsenic content.

3. A class of chemical agents that contain arsenic.

arsenical

1. pertaining to arsenic.

2. a compound containing arsenic.

arsenical herbicide

includes monosodium or disodium methanearsonates. See also organic arsenical (below).

Next, utilizing an in vitro extraction procedure that simulates the human gastrointestinal tract, we estimated the bio-accessible iAs in rice and provided an upper-bound assessment available through a quantitative (complete speciation of all arsenicals in a solid rice sample) As speciation-based analysis using ion chromatography inductively coupled plasma-mass spectrometry (ICICP-MS).

A just published preclinical article, "Darinaparsin induces a unique cellular response and is active in an arsenic trioxide-resistant myeloma cell line", by Boise et al in Molecular Cancer Therapeutics May 2009, further elucidates the mechanism of action of darinaparsin and highlights substantial differences between darinaparsin and inorganic arsenic trioxide, aspects of darinaparsin likely to be included in the discussion session following the abstract presentation, "Mechanisms of Action of Arsenicals in Hematologic Malignancies".

From 10,451 participants in the NHANES 2003-2010 urine arsenic subsamples, we excluded 387 missing total urine arsenic, arsenobetaine, or DMA; 229 who were pregnant; 880 who were missing BMI, cotinine, urinary creatinine, or education information; and 5,626 with detectable arsenobetaine because seafood arsenicals markedly contribute to total arsenic exposure and DMA and make it difficult to evaluate the contribution of other foods to iAs exposure (NavasAcien et al.

Patent and Trademark Office for patent applications numbered 11/252,966 and 11/349,043, covering claims for various organic arsenic compounds, including purified crystalline darinaparsin (ZIO-101), glycolic arsenicals, and the oral pharmaceutical composition of an organic arsenic compound, and their use in the treatment of cancer.

Patent and Trademark Office for patent applications numbered 11/252,966 and 11/349,043, covering claims for various organic arsenic compounds, including purified crystalline darinaparsin, glycolic arsenicals, and the oral pharmaceutical composition of an organic arsenic compound, and their use in the treatment of cancer.

All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.