2am: Artichoke Basille's Come the witching hour, the third location of this celebrated slice shop is colonized by Chelsea club kids. It's four times the size of the East Village original, which means plenty of seating for large, rambunctious groups. In addition to the signature creamy spinach-artichoke pizza, there are expanded options like a salty-crunchy "burnt anchovy" pie and giant bowls of hearty pasta fagioli. Be warned: There's a strong popped-collar quotient at this hour. 114 Tenth Ave at 17th St (212-792-9200). Kitchen open until 5am.

5am: Donut Pub The decor hasn't changed much since the 1964 opening of this 14th Street hole-in-the-wall. Claim a swivel stool at the counter and select your pastry of choice from the trays of handmade, old-fashioned doughnuts lining one wall: Expertly twisted French crullers, puffy Boston kremes and finger-staining sugar jellies ($1--$2) are all staples. Gussied-up MePa partyers file in to sate their late-night sweet tooth, but there's a solid old--New York clientele, too: Ex-beatnik regulars are a refreshing fixture, as is the occasional crazy—on a recent visit, a woman flashed her breasts and demanded free coffee. 203 W 14th St between Seventh and Eighth Aves (212-929-0126). Kitchen open 24hrs.