To quote myself from another thread:
[Spoiler for people that haven't done Hanako's bad ending yet]

Well, you end up not going outside with her and the next day (or a few more later, can't quite recall) she starts to flip shit and screams at, telling you that she doesn't want a white knight in shining armor and wants to be treated normally.
Was quite hard to see such a shy and timid character suddenly scream at you.