Built-in Quality

A stringent validation process ensures the highest quality data possible. Each data point is performed in duplicate. Strict quality control protocols ensure that any assay results not meeting set specifications will be automatically repeated. EC50 or IC50 value determinations for each GPCR are performed with known agonist and/or antagonist (when available) to determine data validity and consistency.

More detail around the protocol, specifications, and controls can be obtained in our customer protocol and assay conditions guide, which is available in the PDF downloads on the right.

All of the functional, GPCR-specific GeneBLAzer® and Tango™ cell lines used in the SelectScreen® Cell-based GPCR Profiling (SSCG) Service provide superior response profiles as a result of optimization of assay conditions and selection of high-responding cell populations. All GeneBLAzer® and Tango™ cell lines in the portfolio were researched and developed by Invitrogen; we ensure the consistency, reliability, and performance of each cell line. In fact, the same cell lines that we use in our service can be purchased by our clients to perform internal follow-up experiments. GPCR-specific GeneBLAzer® and Tango™ cell lines:

Are division arrested or cryo-preserved to avoid variability associated with cell division

Listed below are the GPCR targets available for profiling. Our list of targets represents a cross section of GPCR families, with most of the GPCRs falling into the Class A category of GPCR targets, with a smaller number in Class B. We will continue to expand our panel of GPCR targets, with emphasis on a broad representation of as many families as possible. Check back often for updates to this list.

If your target of interest is not on the list below, additional catalog GPCR cell lines may be profiled using our Custom Services. View the entire list of GPCR cell lines available.