I know some people might think it but I don't think RE needs a reboot theres too many loose ends that havent been tied up.

The one I always go on about is the ending of RE4

<Spoilers>

Ada takes the Sample but dosen't give it to Wesker and she says that she knows Wesker isn't stupid and tough times lay ahead. Well Wesker got the sample in RE5 so we need to know how the hell he got it.

and who are the other corpoation Ada was working for...the "Organization" the rival of Umbrella.

I think this is why Leon and Ada will be in RE6. Hopefully not co-op like RE5 but with Ada getting a small side game like in RE4.