The chemistry of metaphosphate acids has historically been studied in aqueous media, where acid-catalyzed hydrolysis and solvent leveling effects of these strong acids have prevented their observations and rigorous ...

Polyhydroxybutyrates (PHBs) are biodegradable polymers produced by bacteria in the form of insoluble granules for carbon storage. Insights into the mechanisms of granule formation are important for improving commercial PHB ...

(cont.) Identification and characterization of T cell epitopes derived from infectious agents or vaccines can greatly enhance the ability to study and eventually direct the immune response. This work contains a description ...

Strained cycloalkynes have been of interest to organic chemists for many years due to their exotic structure and their potential utility as synthetic building blocks. This thesis examines the generation of cyclohexyne ...

Progress towards the total synthesis of gambierol inspired by the biosynthetic hypothesis for ladder polyethers is described. Syntheses of the ABCD and FGH fragments have been completed in 29 and 3 1 steps, respectively, ...

Protein glycosylation is an important process because of the great diversity of glycoproteins that can be produced by the introduction of different oligosaccharide sequences. Our group has made significant progress in the ...

Studies directed toward the synthesis of the A-ring portion of glycinoeclepin A are described. The enantioselective synthesis of key diketone intermediate 128 in four steps from 2,2-dimethyl-1,3-cyclohexanedione (5) has ...