TOYOPEARL MX-Trp-650M is a high capacity mixed-mode resin used for the purification of monoclonal antibodies and other proteins. This multi-modal resin maintains dynamic binding capacity (DBC) at elevated feedstock and buffer conductivities.

In addition to fast binding and elution kinetics, TOYOPEARL MX-Trp-650M minimizes the amount of WFI needed for either feedstock dilution during capture or column elution further downstream, leading to lower in-process pool volumes and higher throughput.

TOYOPEARL MX-Trp-650M maintains a high DBC even after extended CIP (clean in place) cycles using 0.5 mol/L NaOH.