Less than an hour after suffering the injury, Shaw wrote on Twitter: "Thank you everyone for your messages, words can't describe how gutted I am, my road to recovery starts now, I will come back stronger."

Former PSV player Memphis Depay scored the opener for the visitors in Eindhoven, before Moreno headed in an equaliser on the stroke of half-time.

Luciano Narsingh then nodded home in the second half to secure victory.

'A very bad tackle with two legs'

Moreno went over to see Shaw as he was taken off the pitch

Mexican centre-back Moreno escaped censure for the challenge on Shaw, and Van Gaal was unhappy referee Nicola Rizzoli took no action.

"A boy who came to Manchester United at 18 years old, it was very difficult, and the next season he plays fantastic and then that happens like this," said the Dutchman.

"When I say it is a red card and penalty, you will say I am a bad loser. Every word I say is taken in the wrong way. It was in the 18-yard box and it was very bad tackle with two legs.

"I'm not a doctor so I cannot say, but when you have a double fracture it is four to six months. But you can never say that in advance.

"He won't play in the group stage, I don't think. I hope he will play again this season."

'Hector was not out to injure anyone'

PSV manager Phillip Cocu expressed sympathy for Shaw, and said Moreno had not intended to hurt him.

The former Netherlands midfielder said: "We are all sorry about Shaw's injury.

"Hector is a player who went for the ball and was not out to injure anyone but it didn't look good."

'A devastating blow'

Shaw wrote a message on Twitter within an hour of the injury being sustained

Analysis from chief football writer Phil McNulty: The serious injury sustained by Luke Shaw is not only a devastating blow to the 20-year-old, who had made such an outstanding start to this season, but also to Manchester United and manager Louis van Gaal.

Before the start of the campaign Van Gaal said: "I think that this will be the season of Luke Shaw - that I believe." Now those hopes have been cut down by an injury that looked so bad that the defender will be sidelined for months.

In a somewhat stodgy start to the new season for United, Shaw had shone as he looked leaner, sharper and more settled than during a mixed first year at Old Trafford.

The sight of the left-back being taking on off an stretcher also capped a poor day for England manager Roy Hodgson after Arsenal midfielder Jack Wilshere was ruled out for three months as he requires surgery on a hairline fracture of his left leg.

What could Shaw miss?

194 days: England play Germany in a friendly (26 March, 2016)

212 days: Henrik Larsson's recovery time after a double leg break

218 days: Bryan Oviedo's recovery time after a double leg break

243 days: Final day of the Premier League season (15 May, 2016)

250 days: FA Cup final (21 May, 2016)

252 days: Aaron Ramsey's recovery time after a double leg break

269 days: Euro 2016 begins in France (10 June, 2016)

296 days: Eduardo's recovery time after a double leg break

299 days: Euro 2016 final (10 July, 2016)

Shaw's United team-mates react

Shaw was inundated with messages of support on social media.

Goalkeeper David De Gea said "defeat hurts, but Luke Shaw's injury hurts even more".

Defender Chris Smalling said his "thoughts and prayers" were with his team-mate and midfielder Ander Herrera wants Shaw to "come back soon, my friend".

Messages of support for Shaw

Match of the Day presenter Gary Lineker

Former England striker Alan Shearer

Shaw's former club Southampton

Shaw tweeted a reply to Southampton

Former Southampton team-mate Jose Fonte said on Instagram: "Really upset by what happened just now but I know my boy is strong and will be back stronger then ever! Wishing a speedy recovery to Luke Shaw. Love you mate."