Summary

A range of solid phase immunoassays have been developed using enhanced chemiluminescence to provide a signal which can be measured in a qualitative or quantitative manner. The “Amerlite” anti-HBs assay has been used routinely to test more than 3000 post-vaccine anti-HBs levels. The results show that 5% of vaccinees are non-responders, but that more than 30% produce antibody levels greater than 1000 mIU/ml.