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Abstract

A fluorescent cationic core-shell nanoparticle efficiently enters into cells with high transfection efficacy. A FNP/CHT10-dsRNA complex is orally fed to insect pests and knocks down a midgut-specific chitinase gene of the Asian corn borer, which leads to death. This is the first report on the genetic control of insect pests through a non-viral gene delivery system to knock down key developmental gene expression.

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Publication History

Issue published online: 3 September 2013

Article first published online: 24 June 2013

Manuscript Revised: 19 April 2013

Manuscript Received: 15 March 2013

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