The more serious of the collisions, reported at Mile 225 at 3:05 p.m., closed the highway while a LifeMed Alaska air ambulance landed.

Details surrounding that incident remained unclear at 10 p.m. Monday, but a company spokesperson confirmed the other crash involved a Princess Cruises tour bus.

A motor coach driven by 21-year-old John Snyder of Trapper Creek was en route from Mt. McKinley Princess Lodge to Denali when it was rear-ended by a semi-truck carrying a double tractor trailer, according to Princess

Alaska State Troopers report the truck was owned by Lynden Transport driven by 39-year-old Jason Avila of Wasilla.

Avila was flown to a hospital to be treated for injuries that are not considered life-threatening, troopers report, and the passengers apparently have a similar prognosis.

"There were 44 guests," said Bruce Bustamante, a Princess spokesperson. "10 were injured, but thankfully the injuries do not appear to be life-threatening."

That crash occurred near Mile 169 of the highway and was reported to troopers at 2:52 p.m. The bus had stopped at an Alaska Railroad crossing, but the semi did not stop, according to troopers.

The injured were taken to a hospital for treatment, including some who were transported by a LifeMed Alaska air ambulance.

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