Fluoxetine vs. Nortriptyline in preventing post-stroke depression

Completed

Results

During the 3-month treatment period, 1 minor depression developed in the fluoxetine group (N=13), 1 minor depression developed in the nortriptyline group (N=13), and five minor depressions developed in the placebo group (N=15), indicating a statistically significant (P = 0.05) reduction of minor depression in the treated groups. No instances of major depression were reported.

Recruitment

Gender: Both

Study Size: 48

Follow Up: 21 Months

Principal Investigator

Kenji Narushima

The University of Iowa College of Medicine
200 Hawkins Drive, 2887 JPP
Iowa City, Iowa 52246-1057

Professionals

Education

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This project is supported in part by the NIH Specialized Programs of Translational Research in Acute Stroke (SPOTRIAS) Network, and NINDS grant 3P50NS055977 to Washington University in St. Louis School of Medicine and UT Southwestern Medical Center.