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Topical dutasteride (Topicals & Shampoos)

posted by brm, his room, 18.12.2007, 22:41

Frankly, I don't know what we can make of this information.
1) a quick turnover in vitro generally points to a quick turnover in vivo. But a slow turnover in vitro doesn't necessarily induce a slow one in vivo
2) Above all, the indication they give is about the HALFLIFE of these complexes. But what do we care? These complexes are the dihydrofinasteride complexes AFTER the chemical reaction, that is, inert products unable to neutralize any other DHT molecule. The only relevant point is the halflife of the reactant: finasteride and dutasteride themselves. And once again, because of this, your point is a good one.

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