SIGLEC5 Antibody (PA5-11676)

Performance guaranteed

Purchase with confidence, knowing that we stand behind
the performance of our antibodies with the InvitrogenTM
antibody performance guarantee. If an InvitrogenTM antibody
doesn't perform in your experiment as described on our website
or datasheet, we'll replace the product at no cost to you, or
if you prefer, we'll provide you with a credit for a future
purchase.*
Learn more.

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C

Tested Applications

Dilution *

Western Blot (WB)

1:1000

* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the
product for use in their own experiment using appropriate negative and positive controls.

Background/Target Information

SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. This protein binds equally to alpha2,3-linked and alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. This molecule is expressed by monocytic/myeloid lineage cells. SIGLEC5 is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differenciation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.