I am going to the surgeon on Monday and I will let everyone know what his decision is. If this problem is from the clip at the very least I can let other woman know to really think this over. I had no marks or discoloration on my breast and now I do. Its not only the reaction that bothers me, but having to expose my breast to strangers, whether they are drs or not. Its such a private part. It is embarrassing having to whip out my breast to show someone what is going on. Such a horrible feeling.

I did try to get coverage with the insurance, but the form they sent out to me had nothing on it pertaining to what I was asking for. I should have pursued it with someone higher up, but I have other illnesses going on, and I am just too tired to fight.

I called the company that made this clip to see if there were complaints like mine, they told me know. There recommendation was to try the Internet for help. Some help they were.

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Hi Karen - I am sorry to hear that you feel this way. Myself I feel that after 8 breast surgeies, all the numerous tests, dr. visits, and radiation - that exposing myself is no big deal anymore. You get used to it over time.

I'm not sure what type of "marker" I have placed within my chest wall, but my breast surgeon put it in there when she removed the remaining cancer after I did not get clear margins the first time. It was something that she and my radiation oncologist decided, so it would make getting localized radiation more exact. I'm just not sure what metal make up it is. It's been inside my breast along with a tissue expander as I was going through reconstruction when my plastic surgeon found my cancer returned (cancer twice in a 3 yr period!). I have not had any problems with it, but I also know that it will most likely be removed once radiation is complete and I finish up the reconstruction process.

I hope for your sake you get to the bottom of this problem and are feeling better soon!

Karen - I also had a small titanium marker placed in my breast after stereotactic biopsy was completed, which is still there. I did not have the same problem as you, however, after a year I still have some intense itching on the breast near the biopsy site. The itching was extreme for the first few months, and when checking with the doctor, I was only told to use lotion, that it must be dry skin. Well, it obviously had nothing to do with the outer skin, I had told her the itch was where the marker had been placed, and it itched intensely, and felt like something was crawling under my skin in that area. She seems to think I'm a bit looney, I guess, and totally dismissed the entire thing. Since I am allergic to all types of things, I inquired if she had ever heard of anything similar, or if I could be allergic to the metal or a component used in the marker. She stated she was certain this was not the cause. So, I have not seen any relief, and although it is not as extreme as it was for the first 12 months, I still have symptoms of itching and the crawling feeling. I personally don't think it will ever go completely away, but I just get dismissed by anyone in the medical profession whenever I bring it up. So, I just deal with it. Frustrating as it is. I wish you well, and hope after this has been removed that you are able to move forward without any more of the unpleasant symptoms or side effects from this. Please keep us updated, and my thoughts and prayers are you. Donna

I work in a concierge medical practice and one of our patients had a core guided breast biopsy. she is having a lot of pain and discomfort. I have been trying to do research in re: to this clip which is a standard INRAD clip it is made of titanium and PVC. PVC is polyvinyl acetate. it is used in chewing gum, glues etc. the allergy could be from the PVC not the titanium. However, the reaction could also be from the foreign body itself. sometimes your body doesn't like things that shouldn't be there and it wants it OUT NOW! unfortunately, the only way to get rid of these symptoms is to surgically have the marker removed. Thought I would pass this information along! hope it helps

I had a core breast biopsy in which a titanium clip was inserted. I have been in excruciating pain ever since, to the point that I had to be hospitalized. I have been told over and over that it is not possiblt that the clip is bothering me, however I feel very strongly that it is. I wasn't in any pain prior to the procedure and the doctors can noot find the reason for my pain, yet they continue to dismiss the possibility of a reaction to the titanium clip.

Do you know anyone who had the clip removed and whose symptoms/pain went away? Any information or advice that you have would be helpful. I am tryingto locate any information that I can provide to my doctor to show that there are indeed others suffering from the clips.

Hello, I also had a breast biopsy on Jan 25 2010 and ever since breast infection and symptoms exploded... was put on anitbiotic for 3 weeks but still had terrible breast pain and swollen lymph nodes... they even did a sentinal lymph node biopsy at same time as lumpectomy last Wed. as it was showing possible metatasis... final path report showed no cancer in lymph node but the site where the clip was showed fat necrosis with central hemorrhage and centrally with the area of the necrosis is the metal clip. I had the clip out the at the lumpectomy time and my healing has been very fast.. it will be a week tomorrow and I feel so much better. I also asked if I could have been having a reaction to the clip and was pooh poohed.... keep pressing as now I know it caused me excruciating pain for the month it was in me...I was so sick and I think everyone thought I was crazy.

Thank you so much for sharing your story. I am glad to hear that you are feeling better. I did have the clip removed and the pain went away immediately. I don't understand how so many in the medical profession can continue to act like this is in women's heads. From the stories that I alone have read makes me believe that women should be notified prior to their procedure that there is a posibilty that they could have a bad reaction to the clip.

Wow! so glad to read this. I have been worried because ever since I had a biopsy marker placed after a stereotactic biopsy my breast has been itching. I go back soon for a one-year follow up so will ask the doc but it is good to know someone else has experienced this, just in case they try to tell me it is in my head.

I glad to hear this, next Tuesday I go in for a sterotactic biopsy and was told that a marker will be placed inside. After reading all the stories here I know what to look forward to. Also if the itching begins I will know why. Thank you for sharing with us.

I was just diagnosed with invasive ductal carcinoma after a stereotactic biopsy. I too had the titanium clip placed and have been in pain ever since. I know without a doubt that this is an inflammatory response to the clip as I was not in any pain before the biopsy. I had the expected initial soreness after the procedure and a substantial amount of bruising. After the initial soreness faded I was left with this irritating sensation and shooting pains, as well as severe nipple tenderness. My primary doc has placed me on an anti-inflammatory med as well as a pain med. I will be having a lumpectomy in the near future and I can tell you with all certainty that this clip will be removed at that time, as I will insist upon it. I cannot live with this kind of pain for the rest of my life.

No one would want you to live with pain for the rest of your life, Maggie - that certainly defies the Hippocratic Oath! Be sure to tell the surgeon ahead of time about your pain/tenderness, and that you absolutely want that titanium clip removed, no arguments accepted, OK? Good luck with your lumpectomy - hope you get clear margins first time out. PJH

Hi, I am so grateful to be able to find people who can relate. I too had a clip inserted in Dec and am feeling worse and worse. I am now trembling in my lower extremeties and hands almost constantly. I believe it is related and the dr told me that it is impossible for it to have any neg effect since it is so small. Ha! I would like them to have it placed in their breast and then give me an intelligent answer. I too feel like the medical profession is ignoring any claims of adverse reactions. She said in her 20 years that no one has ever had a problem. Hard to believe. Can you tell me how you did with the surgery when it was removed? I am looking for a surgeon to remove mine and would love to know if you are close to my location. I am in Georgia but would go anywhere to have it removed. Thanks so much!

Thanks so much for sharing your info with us! I am really concerned now since I am having continual shking and trembling in my legs, feet, & hands. It is getting worse. Do you have any further discovery concerning these clips? Do you know of any good surgeons who are willing to remove these? Thanks for caring!!!

I am sorry to her of your pain. I am in the Cleveland Ohio are, but I would imagine you should be able to find someone in your area whow would be willing to remove it. I do know that I had to go to a number of doctors & suffered for an entire moth before having mine removed though. I was lucky enough to find a surgeon who had previously had patients that had issues from the clip.

I unfortunately had picked up a surgical site infection, but I guess you run that risk with any operation, but the pain feom the clip was gone the same day it was removed. I had had a second pain, inmy chest wall, that I had had from the original procedure & that I am still dealing with, however it is nothing like the pain that was from the clip- I could not have done anything, work scholl in that kind of pain, and am grateful I found a doctor to remove it.

Thanks for your response. i am glad you could find a doctor who could help you out. Sounds like you have been through a lot. I too, believe that this is a reaction from the clip. The doctor I saw said in her 20 yrs she has never seen anyone have a reaction to the metal. But she did say she can't say 100 percent that it could not happen. I am wondering if it is effecting my nervous system. Anyway, I will continue to look for a surgeon who will remove this. The breast surgeon I saw was concerned about the surgery deforming my breast. How has your surgery been? Anything to prepare me for the removal? She said it would be a 2 inch incision.

The incision was about 2 inches maybe 3, but it was on the edge of the where the lighter skin color met the darker skin color of the nipple area so that it helps to camoflauge it. It has sa bit of a opuckered look but I have been told this will fill in with time. I would take the scar any day over the pain so it was worth getting it removed. I would suggest making sure that you have some good support bras or even sports bras to wear afterwards. The extra support seemed to help.

Hi - I am from CA and had a core needle biopsy and also had a clip inserted about 7 weeks ago. I found out I have ADH (atypicial ductal hyperplasia) and have to have surgery in a week.

The problem is I have been having a Horrible sore throat for over 6 weeks now.

I have been to the Doctor for the sore throat and he thinks it is viral due to the fact all throat cultures came back negetative. I Never have had a problem with my throat and certainly nothing that would last this long. I have tried every remedy imaginable and it will Not go away.

Then all of a sudden today my husband asked me when Excactly did you start getting the sore throat - was it before your core needle biosy or after. I said a couple of days after. I got a low grade fever and chills and then just this raging sore throat. That's when my Husband said - I bet you are having a reaction to the Titanium Marker they put in you. You body is trying to reject IT!

Wow I wonder if that could be possible. Well I have my Surgery in a week for the ADH - so guess what - I am going to ask my Surgeon to Remove the Marker!

We will see if my throat finally quits hurting after that! Any thoughts???

Definitely have the marker removed. A number of women seem to have adverse reactions to titanium, and I've read about many whose symptoms have disappeared once the clip is removed. So make sure it's taken out when you have your surgery, OK? Good luck - PJH

Dear PJH, I would so much appreciate it if you could tell where you read about the symptoms disappearing after titanium is removed. I have been communicating with others on medhelp.org regarding trouble with titanium dental implants. We are all contemplating removal of various sorts of titanium which has become osseointigrated into the jaw. We would love it if we could find people who have gone through with removal of titanium and since have had their symptoms disappear. Any info. would be helpful. Thanks.

Right here on this site, I've read from at least one woman who said her symptoms disappeared. Not sure which post it was on - try searching "titanium" and see if you can find the appropriate threads... PJH

Thanks to all the women who have posted on this site and shared their stories. A titanium breast clip was placed in my breast after a biospy on April 30, 2010. On the 3rd day I noticed that I was out of breathe after walking up 10 stairs. On the 4th day I woke up with a sore neck. On the 5th day, the sore neck was much worse and I could not turn my head from side to side. The breast pain from the biopsy is gone by day 6 but there is a new pain in the breast. It is an achy, heavy feeling. The pain is still in my neck, but has now also moved into my shoulder, shoulder blade, down my arm, and up into my ear and my jaw-all on the right side which is the side the biopsy was on. I do not feel well and I know there is something wrong. I am advised from the nurse at the breast center to see my surgeon who ordered the biospy but did not perform it. She is out of town so I am referred to her partner. I am also having tingling and numbness in my right hand. The surgeon completely dismisses the possiblity that my symptoms could be due to the titanium clip. My pain continues so I decide to go see my primary health care provider who is a nurse practioner and is a very dedicated health professional. She listened intently and concluded that the titanium marker was the most likely cause of the symptoms I am having. She referred me to a breast specialist who is also a surgeon. This surgeon performed an ultrasound and noticed that there was a hematoma present. She agreed that the clip could be the cause of the problem (her nurse however was adamant that there was no possible way that the clip could be causing the problem) but she prefers that we wait until the hematoma is gone and the breast has healed better before removing the clip. She also thought it was possible that the hematoma could be causing the pain. I agreed to wait her recommended 4 weeks. After 2 weeks the pain became much worse. I am now experiencing sharp stabbing pain and biting pain in the breast that will sometimes cause me to flinch. After the 4 weeks she repeats the ultrasound that showed the hematoma was almost gone and she concluded that the hematoma was not causing the pain and that it must be from the clip. She did say that she had not heard of this happening but that didn't mean that it couldn't. She removed the clip without taking me to surgery. After 4 days, the pain in my breast was completely gone. The other symptoms are slowly resolving. I do still have pain in my neck and my shoulder but I feel it is slowing getting better.

If you are having symptoms that are not normal, please listen to your body and then find a health care professional that will listen to you!

Good for you for being persistent and finding the right doctor to help you. It is very frustrating when medical people insist that an outcome that is unusual is impossible! I'm glad that you are feeling so much better. Thanks for sharing your experience here.

The FDA has a website where you, the patient, can report any adverse reactions to medical devices such as the titanium breast clips. It is so important that those of us that have had a reaction to the clip report it. Just type in MedWatch in your search engine and you will find the site. It is also called MedWatch online Voluntary Reporting Form. You won't be able to fill in all the information and that is fine, just fill in what you can. It is the same form that the facility that did the breast biospy can use. But please don't rely on them to report the adverse event, also you can provide the details that they can't.

The form is very easy to fill out and won't take much of your time. If you prefer you can call them at 1-800-332-1088 to report the adverse reaction also.

THe FDA then reports this information on the Maude Data Base, which you can look at online.

It was a surgical procedure but she was able to do it in the breast biopsy room where they perform the stereotactic biopsies. I was given 15 mg of Valium before the procedure and it worked very well, I don't remember much about having the procedure done. I never felt her numb the area or felt the inicison. I have about a 1 to 1/2 inch scar. I had 2 stitches and a lot of surgical glue that stayed on for about 4 weeks. I had to have someone drive me home. They had to put me in a wheelchair and take me to the car (as I said, the valium worked really well!) but after about 45 minutes I was able to walk by myself. The incision was sore for about 6 weeks, but I quit applying ice too quickly and as soon as I started doing that again it really helped the pain. It was nice not having to go the operating room, having an IV, and being given anesthesia but if that had been the only way to have it removed I would have done it.

I had no mass/lump, no cancer, no pre-cancer. Now surgeon tells me I have atypical hyperplasia something or other. NO MORE MAMMOGRAMS for me since I found this link on mammograms causing cancer. http://www.healingdaily.com/conditions/mammograms.htm. Pretty soon, they will just skip the mammos and we'll just go in for our "annual biopsy." lol.

CHICAGO - Low-dose radiation from annual mammography screening may increase breast cancer risk in women with genetic or familial predisposition to breast cancer, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

"For women at high risk for breast cancer, screening is very important, but a careful approach should be taken when considering mammography for screening young women, particularly under age 30," said Marijke C. Jansen-van der Weide, Ph.D., epidemiologist in the Department of Epidemiology and Radiology at University Medical Center Groningen in the Netherlands. "Further, repeated exposure to low-dose radiation should be avoided."

Women who are at high risk for breast cancer need to begin screening at a younger age, because they often develop cancer earlier than women at average risk. However, according to Dr. Jansen-van der Weide and colleagues, young women with familial or genetic predisposition to the disease may want to consider alternative screening methods to mammography, because the benefit of early tumor detection in this group of women may be offset by the potential risk of radiation-induced cancer.

According to the American Cancer Society, there is strong evidence supporting the benefits of mammography for women after age 40. However, there are conflicting reports regarding the benefits of mammography for women under 40. Alternative screening methods such as ultrasound and MRI may be made available to younger women, but are generally used as an adjunct to mammography.

The American Cancer Society recommends that some women at high risk (greater than 20 percent lifetime risk) should have MR imaging and mammography every year, typically beginning at age 30.

The researchers conducted an analysis of peer-reviewed, published medical research to determine if low-dose radiation exposure affects breast cancer risk among high-risk women. Out of 47 articles found on the topic, six were selected by the reviewers for inclusion in their analysis. Four studies looked at the effect of exposure to low-dose radiation among breast cancer gene mutation carriers, and two studies researched the effect of radiation on women with a family history of breast cancer. Using data from these studies, the researchers were able to calculate pooled odds ratios to estimate radiation-induced breast cancer risk.

The results showed that among all high-risk women in the study, average increased risk of breast cancer due to low-dose radiation exposure was 1.5 times greater than that of high-risk women not exposed to low-dose radiation. High-risk women exposed before age 20 or with five or more exposures were 2.5 times more likely to develop breast cancer than high-risk women not exposed to low-dose radiation.

She noted that this analysis is based on a small study sample and should be interpreted with caution. Dr. Jansen-van der Weide also pointed out that these results apply only to specific high-risk groups of women. Women at average risk were not assessed in this study.

In general, early detection with mammography and prompt treatment can significantly improve a woman's chances of survival. More than 90 percent of women whose breast cancer is found in an early stage will survive. For young, high-risk women and their doctors, it is important to weigh the benefits against any potential risk when making a decision about annual breast cancer screening with mammography.

Yes, I know about this study. It would only apply to women at high familial or genetic risk (those at genetic risk comprise less than 1% of the population), and only when they're young. This study is no reason for ALL women to decide they shouldn't have screening mammograms, which is the impression I was trying to avoid giving. But thanks for posting this - if readers read it all the way through to the end, it does include the whole story. Be well- PJH

Hi, I too having major pain in my left breast - biospy and marker left Dec 09.

Summary, pain masked as acid reflex or hiatal hernia, 3x in the ER, CT heart, then GI and endoscopy. A lot of pain over the last month and escalating.

CT heart great (40 year old no history to warrant issue) Endoscopy normal no acid reflex. Dismissed when I called the original radiologist in my request to have marker removed. It is my belief I am having an adverse reaction to the marker. She not convinced it was, my persistent to find resolution, even though dismissed at the clinic, but directed to the breast surgeon. She did not examine my breast, we spoke in the office, I even stated as I left. You are not even going to do an exam and or an ultrasound to check for a hematoma? Her reply no your xrays looked good in Jul. Well, it didn't sit well with me at all.

I am in excruciating pain for over a month. Ruled out all other possibilities for me thus far.

Bottom line, this is a "CLASS III" device placed in my body and I believe I am having a reaction please remove. Upon calling other surgeons, they will not touch someone else's placement. She can not remove but refer me to the breast surgeon. While there in pain, I request assistance and then gently pushed follow new patient consult protocol. That didn't work for me, I voiced their accountability and perhaps my lawyer should call if I am not taken with regard. Made known this doesn't work for me, I need to see a surgeon asap, and I want a surgeon who would be willing to remove. Same clinic a few hours later. Surgeon (lovely man) examines, we find the pain is extreme to the touch when he examines my breast - at the spot of marker. Ultrasound shows two hematomas, one where the marker is located. Surgery booked for two days later.

I am in a lot of pain, and it is NOT ok to dismiss someones beliefs should they not match with their expert opinion. It is a class III device and it is my belief women having issues, symptoms that are showing up the same for us should be reporting to the FDA. I don't know that process yet. I hope to find releif soon, I am not looking forward to having to have another surgery on my breast, but I need to be out of this horrible pain and willing to keep the process of elimination so I can have my life back.

Use your voice, it is our body and it is not ok to place a class III device without my written consent and then avoid my experience to what I am feeling...

I too have had this burning and pain which I never had before the biopsy and the insertion of the clip. They do not tell you they will insert the clip at least I wasn't told until after the surgery. I go back for the results tomorrow 12/6/ so I know what I am going to insist on!!

Dear butterfly, my mom just recently had a biopsy and had the titanium clip put is...I am very upset about it too...I believe that the severe hives she has is from the clip...they have said it was from the medicine they put on it and recomended benidril and topical benidril too with a loose gause dressing...however I am not totally convinced they are telling me the truth ...I am trying to investigate this more...I live 27 miles south of youngstown ohio...and the one doctor in Mamograghy told me NO BODY has ever had a problem with the clip...I don't believe him...I love my mom and want truthfull answers...thank you...please write back...ajbclb911@att.net thank you Cheryl

Hello, my girlfriend just had x-rays of her right breast,after previosly[two yrs ago} having a titnium marker clip put in her left breast,she seemed o.k with no reactions from the implant,now after beeing radiated she is experieancing alot of pain in the area of the implant is this normal or could the radiation caused a problem she is 44 yrs old.I'm at joesunseri@gmail.com

I had breast biopsy yesterday (Jan 3,2011). I was not told before the biopsy about inserting the clips. However when the nurse told me after the surgery about the clips being placed inside, I got very upset. Don't understand why they are not informing the patients before the surgery. I am terrified as to what adverse reaction the clips are going to cause. At this point keeping my fingers crossed about the biopsy result.

I had a biopsy done in nov and had a titanium clip placed in the breast. I have had symptoms within 3 weeks from swelling starting in the forearms, and face, up the arms (both), back of neck, back of knees, pelvis area, and head, jaw as well. It is quite uncomfortable. My allergist has helped me to rule out all other items except this clip and is int he process of getting a sample of it for a metal patch test. This test has to be performed by the dermatologist and does not have a good track record of having a positive (has false negatives). I see the surgeon who ordered the biopsy which was done at the hopsital under a local by the radiologist this wednesday. The surgeon has already said that he did not place it and it would require extensive surgury to remove. I am reading here that is can be done the same way it was put in. The surgeon already does not believe the clip is a problem and has stated he will not remove unless a positive allergy test is found. My primary care physician says there a re no known cases of this ever being a problem. The allergist believes and says there are cases and it is entirely possible, and is praying for the positive result. The allergist can not make the call to remove it othersise he would. My appointment with the dermatologist is not until March 8 with a long cancellation list. How do you get to someone who will just remove it based on my symptoms? Did insurance cover?

Your story sounds similar to mine. I need resolution. I too had a core biopsy done in Nov (beneign). I started with symptoms within 3 weeks with swelling in my forearms, up the arms, in the arm pits (pain in armpits)around the breast where the biopsy was done, back of knees, pelvic area, top of thighs, head, back of neck, face. My allergist has worked with me to remove all other allergy items, and is down to the most unlikey, the titanium clip. He has made an appointment for me with the dermatologist who will administer a metal patch test of the clip itself. This appointment isn't until April 8 and there is a long cancellation list. This patch test has false negatives. I see the surgeon who ordered the biopsy on Wednesday. The surgeon already has told the allergist that he did not put it in and has never seen this allergy before, even though he ordered it. The surgeon also says it would be an extensive surgury to remove the clip where I have read here that it can be removed the same way it was put in. I also had a very large hematoma and called the breast center within a few days. The nurse stated it was normal and asked the size (1 inch plus, very sore). My breast is still very sore after almost 4 months. How do I go abouth finding someone who will remove it? The allergist can't say remove it although he would like to, my primary care doesn't believe in it, and I don't think I will be getting much support form the surgeon. All along I sit in this reactive phase of an allergy with many supporting allergies to back it up. I am allergic to other metals as I can not wear a watch or certain earrings, zyrtek (allergy med with titanium dioxide), zantac (also has tit di), make ups with tit di, suntan lotions with tit di, plus adhesives, wool... How do you find someone who will believe and remove it? I'd even travel to get this taken care of. What about insurance coverage?

This is a tough situation, obviously. I think, in your shoes, I'd start with the social workers at the hospital where the surgery was done. It's their job to help patients navigate this kind of tricky situation. So - make an appointment, lay it all out, and see if they can help you. Best of luck - PJH

It is my understanding that it can not be rmoved the same way the clip was put

in. I had to undergo regular surgery to remove it. I saw several doctors as well as a dermatologist, however I had to see a surgeon to have it removed. I also had seen other surgeons that would not remove it b/c I saw them shortly after it had been placed and they thought the symptoms would subside. I suffered for a full moth before I saw a surgeon who was willing to remove it. I was so week by the time I saw her, and was blacking out and vomiting from the pain...I guess my point is that I was visible ill and. My insurance did cover the surgery.

Whatever you do, just keep fighting for yourself. My family Dr. was wonderful. He had no doubt that it was the clip making me ill (as I was completely heathy before) so he helped get me in touch with variou doctors. I also didn't need a referral with my insuracne so I just went to multiple drs before finding one who was willing to clean up the mess so to speak.

Thank you for writing back. It has been since Nov 16 that this clip was placed in. Reactions for me didn't begin until about 3 weeks after (even though I started with swelling and soreness in the arm pit and breast) and we thought it was carpal tunnel due to the swelling and even had surgury, then thought allergic reaction and worked with the allergist to remove all other allergen causes. I have been loosing weight as well, am nausious, but not throwing up. The reactions are so intense at times that I am so out of it as my head swells. Can I ask where you live (I am in the Lake George, ny area) and how you were able to find someone to remove it? How do you even choose a doctor who will remove it? We don't have too much faith in the surgeon we see tomorrow who ordered the biopsy in regards to saying he will remove it; however, must go thru the process of having him say no before going elsewhere. We have then exhausted the primary care doctor who doesn't believe this allergy can exist, the allergist who can't recommend it and the surgeon who ordered it. Meanwhile, I continue to get worse with no rest for my body in between as it reacts all the time. We have talked about calling the radiologist at the hospital who did the biopsy, and then somehow finding other doctors, but who?

I just read your note regarding adverse effect from the metal marker inserted. I too was told that no one has suffered from the marker placed in the breast .They are coverung up this becauce they dont want a law suit--wel I got news for them ..I am pursuing this to the fullest extent of the law. Mine was placed 2 months ago ,,several ,surgeon visits,,and it high time womwn are made aware that these markers are harmful and dangerous for women. I have a huge reddish,fever at site and severec itching as well. Goin in this week to follow up the steriods I was put on for one week-obviously it did NOTHING to alleviate the symptoms. I will keep you posted on my continued pain and suffering!

I am online like yourself attempting to find information on the Bard Ultraclip II - Titanium Marker. Do they not hear the cries of the many womany begging for help. Recently I had a biopsy done and they placed one of the titanium markers in my mass. I immediately had severe pain and was dismissed over and over again. All the while my entire body is breaking out in severe hives and my body is starting to shut down. I attempted to get anyone to listen to me as I know when my body is having a reaction. Well let me tell all the women on this site. Please inform yourself prior to having this clip placed in your body. IT IS VERY DANGEROUS! They almost killed me. The only reason they removed it from my body is I ended up in a surgeons office who had to addmit me for emergency surgery last Friday due to the fact that my heart was slowed down to a pulse of 38 and the breathing was shutting off. I agree with you these medical supposed professionals need to take notice there is a problem here. We need to find a way to ban together and get something done. No person and No woman should ever be made to feel like garbage or like they are going crazy again. I do not want to wait until someone is dead to say I should have made my voice loud.

I went in for a needle biopsy 3 weeks ago and was not told that the titanium marker clip had been placed until after the procedure was done. I went through extreme pain through the entire biopsy. Now 3 weeks out, I am still in pain and my breast is so tender, it hurts to wear a bra. I want this clip removed, but do not want to use the same barbaric surgeon that did my biopsy. I am to have an excisional biopsy next month to remove more tissue and the surgeon has agreed to remove the clip. I will be trying to locate another surgeon as I do not trust this doctor. Women need to know before hand about this clip.

Hi.....please go to the bottom of the page where I wrote a big paragraph in bold font and read what I had to say....i think it may be of help to you. I read you said that you will be having a patch test done to test for the titanium allergy....from my readings the patch test does not usually work for this. You need a blood test....please scroll down to my other post for the info....hope it can be of some help to you.

Hi....please check into www.melisa.org ....i wrote a huge post about this below and just want to inform others of the only blood test i've found that actually will test you for titanium allergy. A patch test by an allergist does not work, it needs to be an actual blood test from my understanding. I had my gallbladder removed 9 months ago and have suffered since and had many test all of which determine nothing. I have finally started to wonder if it's from the titanium clips they put in me...which led me to my search. The test is called "the melisa test" "pronounced "meliza"...i am going to be doing it next week or so, they faxed my family doctor a consent form, he faxed it back and now they will ship me a kit that is safe to ship my blood sample in. It is a certified lab in South Amboy that does this testing. I hope this can be of some help. Best wishes....and i hope others read this post too. I don't mean to sound like an advertisement for this, but i know how badly i'm suffering and how sad and depressed i am feeling and if the info i've come across can help another, i feel it's my obligation to pass it along.

I too have two titanium marker clips in my breasts - one on each side. Ever since the first one was placed - my breasts have itched like crazy from inside.

The first one was 4 yrs ago and just had one on the other side. My doctor too told me it was not the clips, but was my "bras" that make me itch - get cotton ones. I have tried all kinds of lotions, oil, soaps, creams. But it is always there.

Sue, I'm so sorry you're going this. It's always disheartening to hear when doctors dismiss your symptoms as something silly like your bra, when you clearly can feel the itching is coming from inside. Have you considered having the clips removed? PJH

Well, I did not know about anyone else having these symptoms until I came across this blog site yesterday. I emailed the manufacturers of the clips, but I doubt I will get a response. I asked the doctor before I had the second biopsy two weeks ago about the chance that the first one was making me itch all the time and she said it was not the clip - it is titanium and there are no allergic reasctions. So, I went ahead with the second biopsy and clip. I did have a reaction as soon as the process was over: cold sweat, nausea and shaking. They told me it was from the meds they injected to numb me. I also had a huge rash and blister from the steri-strips. But those symptoms went away.

I am plagued by constant itching just on my breasts. I will check with my physician about having them removed, now that I know that I am not crazy and not the only one with this problem. Thanks!

Kelly, I am so glad to hear that I am not the only one with symptoms from the marker clip. Since I have gotten the clip I have been having chest pain in the area of the clip, down my left upper arm, and sometimes in my back but, still in the area of the clip from the back. I use to have some burning symptoms in my chest but now since I've had the clip it burns a lot but, I can deal with that I just can't stand having the pain feeling like someone is stabbing me and it's going through my back. I am schedule to have a lumpectomy on the 21st of October 2011 and I will definitely have it removed. I tahnks each one of you lady for the information you have annotated because I know that it is the clip and not me. I also, told the doctor of my symptoms but, he didn't say anything about whether it had to do with the clip or not. I told my husband about the pain and as I'm writing about my symptoms I am hurting. I pray for ever last one of you ladies thanking God for a positive report for those who do not have cancer and I'm asking Him for a positive report for those who don't know their results yet including me and I'm asking Him for a supernatural healing for those who have been diagnosed with the disease.

Hi, I am in Atlanta, Ga. My breast has calmed down and now I am waiting because I have been going to Alternative Health doctors who are dealing with other symptoms and it is helping my overall health. Many women had issues that I have heard from similar to yours and the only way it is resolved is by removing the clip. It may take time but I would keep looking for a good surgeon to remove it. Do your research and ask if they have ever removed a clip before. A plastic surgeon may be a good choice since they deal with the breast. I was ready to go out of state if need be but I do not have the severe sypmtoms you have. Get your husband to complain but don't give up and don't let them tell you it is in your head.

I'm living in Cleveland Ohio, and I have just found out I havd the same shooting pain on my right breast. I had biopcy in July last year, and there was no cancer found. I would like to contact you to get more information about the surgen you had for removing the clip for you. I called my Dr.'s office and his assistant told me that she had never heard about it the clip causing pain in her 30 years perfessionas.

Hi there
The doctor I had went to was Donna Vecchione, she is out of Southwest General in Middleburg hts. My pain ceased the day the clip came out. I am sorry to hear of your suffering. I will keep you in my prayers. The best advice I can give you is to just keep seeking medical attention until you found a doctor that will listen. Please let me know if there are any other questions you may have.
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Yes, I also notice some pain where the two titanium clips remain in my breast since 2009. The doctor and tech who does the ultrasound tell me it could not possibly be the clips. I beg to differ. I have had biopsies before and did not have this problem. It is not a severe pain, just nagging and when I rolled out of bed and hit the floor one night on that side of the breast, I felt sharp pains in the area of the two clips. Doctors should listen to their paitients. I feel like I was part of this doctor's research study and that the clips were not necessary. No cancer, by the way.

Yes, I also notice some pain where the two titanium clips remain in my breast since 2009. The doctor and tech who does the ultrasound tell me it could not possibly be the clips. I beg to differ. I have had biopsies before and did not have this problem. It is not a severe pain, just nagging and when I rolled out of bed and hit the floor one night on that side of the breast, I felt sharp pains in the area of the two clips. Doctors should listen to their paitients. I feel like I was part of this doctor's research study and that the clips were not necessary. No cancer, by the way.

You are right. Doctors should listen to their patients. You know when and where you hurt, and doctors should respect your experience. Your pain could well be caused by the titanium; it could also be caused by scar tissue. I have pain at the site of every surgery I have ever had, and in my case, the problem is scar tissue. Like you, my pain is not severe, and it changes with my movements.

I am so glad that you did not have cancer and that so far the clips have not been needed to check out problems near that site.

Dear Proverbs, Thank you for your story - it gives me hope that I'm not loosing my sanity. I was told that no one else had ever complained about the titanium clip. I've put up with the pain almost 2 years and I've just had it! Did your insurance pay for the removal? The radiologist who put mine in, said he would take it out the same way. How are you doing now that some time has passed?

Hi Daisy, How are you doing these days? I pray you're over it and are well by now. I'm guessing you've received hundreds of e-mails since giving your address on healthcentral.com. I too, tried to send you an e-mail but was told it wasn't a valid address. After so much pain I can hardly stand it for over a year and a half and being told it couldn't possibly be the clip that's causing it, I finally got the bright idea to check "on line" for any other supposedly "crazy" ladies who might have the similar problem. Wow! Was I ever surprised to find all you gals out there. Truthfully I was relieved to know that it's not in my blond head and then I got mad. I was flat out lied to, more than once, when I went for help. It seems like there's this big "cover-up" from the medical community - or is that in my head too? Regardless, I'm scheduling the removal immediately.

Are there any action groups that you know of who plan on bringing this out of the closet? If so, let me know what I can do.

Hi Painter, I'm sorry you are having so much trouble so long after your biopsy. Good for you in doing the research to find out what might be causing your pain. This thread makes it clear that some doctors are not doing a very good job of listening to their patients. Too many ignore patient concerns.

You can register your experience with the FDA, which keeps track of problems with medical devices. You should also report your problem to the manufacturer of the clip. Ask the doctor about the kind that was used. The word cover up would refer to a company knowing that the device caused problems and hiding that information. Most women don't have problems with the clips, so most doctors would not have a sense of how frequent they are. If women having problems report them, then the government can order recalls if warranted and issue warnings if the problems are infrequent, but possible.

My insurance company did pay for the removal of the clip. I would love to tell you that I am pain free and symptom free. I am definetly better than I was but I do still have some issues. I know beyond a shadow of a doubt that the clip was the cause of my pain and symptoms. Unfortunately, I feel like a car that has been in a wreck and will never be the same again.

I'm glad to hear you're dong beter - though sorry you're not back to normal. Time heals - hopefully your last side effects will eventually disappear, and you can put this all behind you... Take care- PJH

I totally agree with you on this issue. I feel highly violated. It is my body and I had prior knowledge of the clip to even assess what possible side effects it could have. I have scar tissue and inflamation around the clip area and a radiating pain up into my armpit and side. I feel certain it is from this clip as it is against every principle I have to put anything in my body without researching it and this inflam ation showed up on the last ultra sound. I am sure you have to have surgery to remove the clip. I am going back to the Breast Center in Orange County about it.

I am incensed when I read this website and see how many are affected and the dismissal of the medical community. I wuld like to know when these titanium clips became standard practice?????

Hi Proverbs, nice to hear from you. I saw my GYN for advice this past week. She was totally against a Radiologist removing the clip and insisted I should see a surgeon, which I will do. Now the question is WHO. The GYN thinks there is a build up of scar tissue and probably inflamation that will have to be cleaned out, but it seems to reason that more surgery will cause more scar tissue. It's been almost 2 years since the clip was put in. I'd hate to think I'll have the same issue with scar tissue after 2 more years. I feel like I'm on a merry-go-round and I'm afraid to jump off. Sorry to hear that your symptoms are lingering but glad to know you're better. Let's pray you keep on getting better with time.

Lesley, I couldn't find an exact date when titanium markers became standard practice. I found quite a few research articles in medical journals for radiologists and surgeons about different types of clips and procedures used to place them in 2002-2003. So I am guessing that they came into wide use about then.

I am sorry you are having such a difficult time with pain and inflammation. Keep in mind that everyone has scar tissue from any surgical procedure. For some people scar tissue can be a problem even in procedures that don't use markers. It is a shame that many of the women who have written into this thread did not have doctors who took their problem seriously. Probably the reason that happens is because of the hundreds and hundreds of the biopsies the doctors perform, most women do not have a problem, so when a woman does, some doctors don't pay attention the way they should.

Well thanks for checking that. I have had no success yet getting a call back from the Breast Center on this so will stop in after work on Thursday and see what I can find out. The U/S tecj there rec that I have a high level ultra sound because of all the inflamation and scar tissue...maybe I can find some kind of creme that eases the ache??

hi my name is diane i am from virginia i had my biopsy on jan 12 2012 since then i have developed a rash, shooting pains and lumps in the breast that wasnt there before. i went to the doctor today however they said no way it could not be from the marker they placed in but i have never had this pain until now please help what do i do any suggestions please call 804-512-7527

Diane, since it has been only a few weeks since your surgery, it could well be that an infection, a hematoma, or other problem related to the surgery, not the marker, is causing the problem. Stitches and/or scar tissue can cause the shooting pains, especially if they are pressing on a nerve. It may also be that you are one of the rare people who has a titanium allergy. Your doctors should have a theory about what is causing your increased pain, rash, and lumps, and they should have a plan of action about what to do about the problem. It can take a while for the bruising and pain from a biopsy to heal, but if your symptoms are getting worse, not better, then you need to be back in the doctor's office. Be assertive about getting answers, but be open-minded about what might be causing the problem. I hope you are soon feeling better.

I stumbled on this site by googling pain after inserting a marker after a biopsy...I had mine put in about 6 weeks ago and have been experiencing some shooting pains, not unbearable, but some pain and since I had no pain before or during Biopsy I thought strange...glad to know its not all in my head....going to doctor in a week and will mention these pains and go from there...since I had Hyperplasmia I go back for another mamogram in 6 months so will def be talking to surgeon on removing....thanks for info
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I HAD 2 METAL CLIPS PLACED AFTER 2 BIOPSIES IN THE PAST MONTH. I AM SCHEDULED FOR A MASTECTOMY THIS WEEK AND LOOKING FORWARD TO RELIEF FROM THIS PAIN. NO ONE CAN TELL ME THAT IT IS NOT FROM THE CLIPS AS IT JUST STARTED LAST WEEK. WHAT'S UPSETTING IS THAT NO ONE ASKED MY PERMISSION TO LEAVE THESE THINGS IN ME. I WAS TOLD AFTER THE FACT. THESE PROCEDURES SHOULD NOT BE DONE WITHOUT THE PATIENTS KNOWLEDGE!!!!!!!

It's unfortunate they didn't inform you about the clips ahead of time; speaks to the fact that we can't trust our health care providers to give us all the information we want, all of the time. It's a challenge, but for best results we probably need to become "expert patients" - do some research ahead of time, then be ready with questions when we speak with the doctor. Best of luck with your surgery - our mastectomy insider tips may prove useful to you. - PJH

I hope your pains subside on their own soon. I'd guess, since you'll be having another mammogram in 6 months, the doctor would want the clip to stay in at least until then. I hope your next mammogram shows no change, and you can relax and feel better - PJH

I had a core needle biopsy and a marker placed. I had unremitting pain from that day forward. Since removing a lump is really up to the woman (the patient), and not the health care provider, after 6 months, I consulted a 2d breast surgeon. He did believe my complaint of unremitting pain after the marker was placed. I had a lumpectomy, with removal of the marker. The next day, while still coping with surgical pain, the stabbing, non-stop pain from the marker was gone. At the post-op check, the doctor remarked that the marker must have been placed on or near a nerve which lead to the stabbing pain.

Good point, Debbie; it's not just a possible reaction to the titanium, but the marker might actually be touching a nerve and causing pain. You're right; pain isn't somethng to ignore, as it's the body's signal that something's wrong. I'm glad you were able to get the clip removed. Take care - PJH

I had a stereotactic biopsy (benign) about a year ago and off and on I have shooting sharp pain where the marker has been inserted. I can't understand why they keep telling women there are no side effects. After reading from some of the women here, and with my own paid - it simply is not true.

Hi, I live in Marietta & just found out I had 3 of these markers put in me a week ago with out my knowledge or permission during 3 biopsies. I have immune issues & am mad as H#** about it. Did you ever find a good doc that would take them out and if you don't mind my asking, what practice / doctor put one in you? Have you heard anything about Millennium in Dunwoody? I have decided to dedicate myself part time for 1 year to fight for women's rights to be informed & have a choice.

My biopsy procedure was at Northside. The head nurse was blonde, maybe Nancy? She assured me you could have it removed later. Lies!

I haven't heard of that group..I am doing better, but I still have shakiness that is associated to coming on right after the clip was inserted. I had names of doctors in CA who would remove it, but I have not gone that route yet. It is a serious surgery and can deform your breast.

I find it quite aggravating and deceptive that the doctors that do biopsies never mention that a possible reaction could occur due to the titanium marker they place within your breast. Rare as that may be, it clearly has happened. What about the fact that the marker can be optional ? Shouldnt they have to mention that ? It is our body - not theirs and we ought to be given that choice. My Radiologist gave me the distinct impression that this was protocol for anyone having a vaccum assisted needle biopsy. We as patients trust our care givers. Instead we ought to question them on every little detail that they intend to do to our bodies. It was explained to me sooooo casually as if it were nothing. Even if just a few patients have reactions, or could have a reaction, it's their job to inform patients it's possible. Why are we not pre-tested for metal allergies ? I had a biospy about 5 weeks ago and the 4th week had a severe infection set in to my breast. It was so tender at the site of the marker it brought tears to my eyes. I went in to have a Radiologist at the hospital check out my problem and he said he had NEVER seen anything like it before. I am currently finishing a 7 day round of antibiotics but something still doesnt seem quite right. I am of course nervous. In my particular case I broke out in a red rash and had breast tenderness. My Gynocologist & I noted the rash was elevated in a couple areas. I knew I had a horrible infection and yet the Radiologist told me it was from a change in my laundry detergent. O really ! An infection that looked like the outline of flower petals all around my breast nipple area. NO where else on my body but my nipple area which was where the marker was placed. Thank God he thought I should see my Gynocologist and she gave me an antibiotic. Otherwise I'd have been sent home with a horrible infection. It looks and feels better but I am still have stabbing pains and a burning sensation on and off. When I asked about the marker and a possible allergic reaction he said in 20 plus years of practice he has never seen anyone who had an allergic reaction and I need to get off the internet. I am planning to have blood work done and sent in to determine if I am having a reaction to the titanium implant marker. This has been a nightmare and it's not over yet. My questions for you are who took out your marker and was it difficult to have them agree to do it ? I understand that it can be difficult to get a doctor to do that procedure. Thank You and Gods Blessings to you for a speedy full recovery and a very long life.

Sharon, I'm so sorry you're going through this; and sorry you're dealing with a radiologist who's too arrogant to accept that it might be an allergy. He's right in that chances are very good it's NOT an allergic reaction; but just because he's never seen it happen - certainly doesn't mean it's not possible! If you continue to run into stone walls, I'd suggest you speak with your hospital social worker; she can help you figure out how to get the clip removed, if it's your decision to do so (and it certainly is your decision to make - no one else's). Good luck to you - PJH

I had he same procedure with two titanium clips implanted and immediately started having terrible pain and the incisions were not healing had fluid coming out of the holes and discoloration. Went to a breast surgeon had a ultrasound done and had fluid collections around both of he markers. The pain became excruciating had major surgery Huey used mamma gram to place wires down to the markers and the surgeon was to remove the wires and remove the clips he failed to get either clip. I have terrible scars. Finally I had a very intelligent radiologist remove them by using reverse mammotone where I had to lay upside down he had never done this procedure before almost broke the machine but he removed them and after the recovery no more pain or fluid collections thank god for a caring husband and a understanding caring radiologist and I am allergic to almost everything almost all meds but it still took a lot of convincing to make them understand I truly was allergic to the clip. Be persistent and it's your body and you can find info on the Internet good luck.
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Hi Karen, I too had a clip marker put in my breast during breast biopsy. Several months later I had much pain in my breast. I had to wait another 6 months before I could take another breat exam by that time over a year had passed. Nothing showed up on my breast xrays or sonagram. Then one day I noticed my nipple swollen and around area pimple like leasions. My Dr. took a sample from my nipple and blood test. It came back as a staph infection in my breast. I now am going to have to have surgery to get clip marker out. I knew I did not like him putting a clip in ther since Iam allergic even to pierce earings. I do not know if infection is gone since I was put on antibiotics for 8 days. I still feel pain and have nipple soreness and pain. Iam so afraid to have it removed but I have too since it is causing staph infection that will not go away till clamp is out. My advice to anyone is if you are allergic to earrings or hyperallergetic don" t let them insert a marker in your breast as staph infection is serious.

Emogene, I'm so sorry you've had this bad reaction leading to a staph infection. The staph infection might have been from some other cause, but if the doctors feel removing the clip wil also help cure the infection, great - I hope they're right. Your advice about knowing exactly what's going to happen before you get a biopsy is invaluable - we all need to be our own best advicates, when it comes to being a patient. Best of luck - I hope you feel better soon. PJH

Jen, it has been several months since the previous posts, so you might want to click on the name of the person you want to contact and send her a private message with your question in case she isn't reading this thread anymore.

Hi - Since this is an older thread, you might want to click on the name of the person you're posing the question to, then send them a private message. That way, you're be more certain of getting an answer. Also, please see my answer to the message you sent me earlier today, OK? Take care - PJH

I was angry to find out after the fact too! The doctor did not say a word as he put the clip into my breast. They should have asked me if I wanted a clip in my breast point blank. Go get 'em. I think it's outrageous to leave anything in someone's body and not ask for their express permission unless it is a life threatening matter in which you cannot ask the patient.

Dear Marker, I agree with you that everyone should be told about the marker. If you read the fine print in the papers you signed, you will probably find that it was mentioned, but the doctor or nurse should have explained its purpose and made sure you knew about it.

A friend of mine is very glad right now that she had the marker. It means that she can have a lumpectomy instead of a mastectomy. Chemo before her surgery reduced her tumor so much that that doctors need the marker to find the area that needs to be removed.

I would like to know about any adverse reaction on the hydromark titanium clip, shape 3 (Hydromark is a water-soluble polyethylene glycol-based hydrogel, which contains a central marker). My reaction on titanium is negativ, but I have very strong pain (neurological) in my breast but also in my arm, my ribs, since 5 months! Maybe it was caused by radiation? or by compression during 1 hour?

I consulted more 20 doctors, and they don't know how to explain my pain.

I would like to know about any adverse reaction on the hydromark titanium clip, shape 3 (Hydromark is a water-soluble polyethylene glycol-based hydrogel, which contains a central marker). My reaction on titanium is negativ, but I have very strong pain (neurological) in my breast but also in my arm, my ribs, since 5 months! Maybe it was caused by radiation? or by compression during 1 hour?

I consulted more 20 doctors, and they don't know how to explain my pain.

Alba, I'm so sorry you're going through this. If you've consulted 20 doctors and they can't help you, then I'm afraid we can't, either - we're not doctors here, just well-read breast cancer survivors. My advice would be to try some alternative healing - acupuncture, for instance, or Reiki. When medical science can't help, it sometimes helps to go the mind-body route. Best of luck to you - PJH

Last Thursday I went in for additional views after a mammogram that revealed a cluster of calcification. I have fibrous breasts and have been called in for additional views in the past ... and they always turned out to be nothing. So I was really surprised when, instead of having the radiologist come out and tell me it was just a calcified milk duct, the technician told me I immediatedly needed an ultrasound. After the ultrasound, they took additional mammomgram views. I only have major medical insurance coverage, so this whole time I am thinking, "How are we going to pay for all this?" They knew I had a child with special needs and told me he needed me and I couldn't take care of him if I didn't take care of myself.

I was told that on Monday (three days later) I need to come in for a biopsy guided by ultrasound. Like your posts that I have read, it was casually mentioned that they would be inserting a titanium marker clip ... and it would be left inside my body! I asked if my body wouldn't react negatively to something foreign. The doctor, who is considered one of their best and about to retire, told me he has never seen a negative reaction in his entire career and that this procedure has been around for 30 years.

Monday also happens to be my birthday, but I said to go ahead with it because I know I will have a rotten birthday knowing the next day or later in the week I have to do this. I figured I'd just get it over and spend the rest of my day letting everyone pamper me. I don't have the money for second opinions and the biopsy is now only a day away, so I didn't figure I'd have time for research.

But I have been having serious second thoughts about this procedure. Especially since I don't feel any lumps (I do a breast exam every month). I did have a lump removed surgically about 13 years ago (it was benign) and I've had lumps come and go. However, I do have a strong family history of breast cancer. So I know I shouldn't mess around.

Here's the question: Based on the post I am responding to, it sounds like I DO have the option of asking for the biopsy without the titanium marker. Is that true? If I ask, is it likely the radiologist will refuse because he will feel he won't be able to detect it as accurately? Is the marker only for future procedures? Isn't the whole point of having an ultrasound-guided biopsy to help them accurated pinpoint the affected area?

I am really a purist. I also have very sensitive skin. I am wondering what will happen if I go in on Monday and say I refuse to go through with this if they insist on the marker.

Last Thursday I went in for additional views after a mammogram that revealed a cluster of calcification. I have fibrous breasts and have been called in for additional views in the past ... and they always turned out to be nothing. So I was really surprised when, instead of having the radiologist come out and tell me it was just a calcified milk duct, the technician told me I immediatedly needed an ultrasound. After the ultrasound, they took additional mammomgram views. I only have major medical insurance coverage, so this whole time I am thinking, "How are we going to pay for all this?" They knew I had a child with special needs and told me he needed me and I couldn't take care of him if I didn't take care of myself.

I was told that on Monday (three days later) I need to come in for a biopsy guided by ultrasound. Like your posts that I have read, it was casually mentioned that they would be inserting a titanium marker clip ... and it would be left inside my body! I asked if my body wouldn't react negatively to something foreign. The doctor, who is considered one of their best and about to retire, told me he has never seen a negative reaction in his entire career and that this procedure has been around for 30 years.

Monday also happens to be my birthday, but I said to go ahead with it because I know I will have a rotten birthday knowing the next day or later in the week I have to do this. I figured I'd just get it over and spend the rest of my day letting everyone pamper me. I don't have the money for second opinions and the biopsy is now only a day away, so I didn't figure I'd have time for research.

But I have been having serious second thoughts about this procedure. Especially since I don't feel any lumps (I do a breast exam every month). I did have a lump removed surgically about 13 years ago (it was benign) and I've had lumps come and go. However, I do have a strong family history of breast cancer. So I know I shouldn't mess around.

Here's the question: Based on the post I am responding to, it sounds like I DO have the option of asking for the biopsy without the titanium marker. Is that true? If I ask, is it likely the radiologist will refuse because he will feel he won't be able to detect it as accurately? Is the marker only for future procedures? Isn't the whole point of having an ultrasound-guided biopsy to help them accurated pinpoint the affected area?

I am really a purist. I also have very sensitive skin. I am wondering what will happen if I go in on Monday and say I refuse to go through with this if they insist on the marker.

You certainly do have the option of asking that the clip not be left in - and yes, it's only left there for the possibility there'll be a future procedure, to guide the surgeon right back to that same spot. Your doctor not ever having seen an adverse reaction in 30 years is probably typical; reactions to titanium, though possible, are extremely rare. Yes, your radiologist will probably react negatively to you asking that the clip not be left; it's a deviation from standard procedure, and s/he may think it leaves open the possibility of a future malpractice suit. Will s/he refuse to do the surgery? Quite possibly.

So, what to do? I'd guess you need to decide just how serious you are about this. Only you know to what degree you're a purist; and whether your sensitive skin might translate to troubles with the clip. You also know your degree of current stress; if the surgery is postponed or cancelled – if you need to do some research to find another radiologist who won't insert the clip – how will you feel? Keep in mind that, despite the responses on this post, statistically speaking a bad reaction to titanium would be a tiny, tiny possibility. There's no easy answer here, unfortunately. Ultimately, you have to decide what's best for YOU; then make it happen. Best of luck to you. PJH

I just wanted to let you know that I went through with the biopsy today. Your information helped me have a really good discussion with the doctor prior to the procedure. He agreed that the titanium marker clip is to help with future procedures, but he said they use that clip in a follow-up mammogram to prove they hit the mark during the biopsy. But he said he could confirm it with an x-ray. So he didn't hassle me at all. He was very nice and really experienced ... The doctor every patient hopes for.

He explained everything he was doing and let me know ahead of time how the popping would sound as he took a biospy. He would say, "One, two, three," so I'd know exactly when he would take it. While prepping me, he first injected a little anesthetic in the outer layer of my skin and then as that took affect, he gradually went deeper and deeper. I literally only felt a prick the first time and then a slight stinging as he injected the anesthetic.

The actual biopsy was painless. It is worse getting a cavity filled! The most uncomfortable part was having my arm extended up under my head. I had to lie still and my fingers were tingling and my arm was starting to go to sleep. They were going to do a follow-up mammogram, and when I asked why, the technician said, "You're right, since you don't have a clip, you don't need one." It all went well. I will know if it is cancerous by Wednesday. Today is my birthday so I plan to take the rest of the day off!

I'm SO glad it all went well for you! Sounds like you have a very good radiologist indeed. Your description sounds so familiar... I still remember that popping sound! I kept thinking "Roto-Rooter..." Anyway, the odds are still with you - about 85% of breast biopsies are negative - no problem. So hold onto that thought, and have a very happy birthday. I recommend chocolate cake – it cures all ills! Let us know what you find out Wednesday, OK? PJH

Dear Charlotte, I am so glad you found a radiologist to take the clips out. I had 2 clips put in and the calcifications are benign, but I have the same problem are you. I have stabbing pain in certain positions. I saw a surgeon and he said he could get one out and try with the other but was not certain about the other. I too will have scars. If you could tell me the name of the radiologist I would like to talk to him and try to find someome where I live in Utah to do the same procedure. You are so kind to write about what happened to you and help others. Thank you very much, Catherine

Dear Charlotte, I am so glad you found a radiologist to take the clips out. I had 2 clips put in and the calcifications are benign, but I have the same problem are you. I have stabbing pain in certain positions. I saw a surgeon and he said he could get one out and try with the other but was not certain about the other. I too will have scars. If you could tell me the name of the radiologist I would like to talk to him and try to find someome where I live in Utah to do the same procedure. You are so kind to write about what happened to you and help others. Thank you very much, Catherine

I hope maybe she might take out my clip. I can't get anyone to admit there is a problem but have developed some atrocious mast cell disorder, sun intolerance, and anaphylactic episodes since the week after it was put it. It is not hyperbolic to say it has ruined my life. (more accurately, IT RUINED MY LIFE!!!!) I told the surgeon I was allergic to nickel and he said it would be fine and I believed him. In went the Hydromark clip. I am also intolerant to polyethylene glycol but no one asked me that either (they should have probably thought twice with putting anything into a girl with a history of guillain barre, nickel allergy, latex allergy, and sulfa allergy). As it turns out, the people who came up with Hydromark don't have an answer for much - Mystery Biotech Company Flees Tuscon. Now, no one in my town (Toledo) will listen to me (They figure I will sue - BUT all I want is to get the thing out before I develop mast cell lymphoma. I don't want to wreck my reputation with a lawsuit! All I want is to use my masters to have a professional career and they treat me like I am looking for a handout). Since it was put in, I can't even have bras touching my skin (no elastic, hooks, spandex, lyrca, etc). I used to have a latex sensitivity, now it is an insane reaction that resulted in my having to discard my entire wardrobe - all because nickel and other metals are sensitizers. (How I am supposed to wear a suit for my job!?! I have no choice but to dress in 100% cotton now). Not surprising - Nickel is widely known for being used in immunologic research to sensitize/increase rats' allergies to other things. I have been denied the record of which type of clip it is. Another doctor I consulted refused to take it out unless he knew exactly what it was and had proof through other testing that I am allergic to whatever metal it is. He also mentioned Munchausens when I showed him pictures of my allergic skin reactions. Oh happy day. All I have is an op note that says "Hydromark." Hydromark only makes two clips - stainless steel and titanium. Either way, there is probably nickel in it (any metallurgist can tell you nickel is ubiquitous, is in metal alloys and contaminates just about every metal). So far, the first breast surgeon consult gave me an mammogram - established the clip migrated. See Evaluation of a hydrogel based breast biopsy marker (HydroMARK®) as an alternative to wire and radioactive seed localization for non-palpable breast lesions I am going broke over this. It is not that I am stupid either - I have three degrees. I should never have agreed to it but I shouldn't have to live this way. A number of allergists have also refused to help. I have never felt so hopeless in my life. I'll be lucky if I don't die of anaphylaxis before someone actually agrees to help me. Not to mention the thousands of dollars I have spent trying to get help. :(

In case the link to the article quits resolving, I am quoting it here:

Mystery Company Flees Tuscon (Hydromark)

December 02, 2008 12:00 am • By Tim Steller Arizona Daily Star

"Florida officials are crowing about luring a biomedical company away from Tucson.

But the company is largely unknown to people in Southern Arizona's biotech circles or at the University of Arizona.

Florida Gov. Charlie Crist issued a press release last week celebrating the recruitment of Biopsy Sciences, which relocated to Pinellas County, Fla.

"Biopsy Sciences' move to Florida is indicative of the state's focus on a future rich in science, research and innovation," Crist said in the press release.

The St. Petersburg Times reported that the company has 10 employees and that it formerly used laboratory space at the University of Arizona.

However Michael Cusanovich, the director of Arizona Research Laboratories at the UA and president of the Bioindustry Organization of Southern Arizona, said he had not heard of the company. Neither had representatives of the UA's chemistry department or the UA's Science and Technology Park.

Company officials could not be reached for comment.

The company developed a product known as the HydroMark, which is described as "a novel ultrasound visible marker" that helps patients by replacing lengthy mammogram-guided procedures with a quicker and more accurate ultrasound-guided procedure that is more comfortable.

● Read more in Wednesday's Arizona Daily Stat/The St. Petersburg Times contributed to this report."

Hello ~ I too, had a sterotactic biopsy performed with no cancer found, however, a "titanium" clip was left inside my left breast. Since this time, my breast pain is so severe sometimes, I can hardly stand it. I went to a "General Surgeon" and asked her to remove it. She removed scare tissue and said that was the culprit of the pain. Since that surgery, the pain has become much worse. Everyone on this thread seems to be having the same trouble. JC Lincloln Health & Breast Reasearch Center in AZ did the Stereotactic Biopsy and did not tell me they were going to leave the marker in. I went to the top and they would do nothing about it and told me to find my own surgeon. I am at a loss. There should be something that can be done about this! This is not in our heads, people! This is real. What can we do?!?!

Yes, most of the people on this thread do have this problem, but keep in mind the vast majority of women who don't have trouble with their marker would probably never even find this thread, much less comment on how everything went fine for them. Nevertheless, it is clear that the marker is a real problem for a tiny proportion of biopsied women and that often these women's doctors are not responsive to their needs. One of our readers did find a helpful doctor who sent her for allergy testing. When the allergy test showed that she had an allergy to titanium and some other metals, the surgeon said the clip needed to come out. I would encourage you to ask around about surgeons who are good at listening to and believing patients. Nurses and physical therapists are often good sources for recommendations if you can get them to talk "off the record." Your primary care doctor might also have some ideas about who would be the best doctor to take out the clip.

Many women have persevered and had the marker removed. If you're determined to have the marker removed, it sounds like you're going to have to advocate for yourself - as they told you at "the top," you have to find a surgeon willing to do the surgery for you. First place I'd start? A social worker at your local hospital, as I assume the breast center you accessed doesn't employ social workers. It may be a long road, with LOTS of patience and strength required - but it's that or leave the marker in. Action trumps anger and worry and frustration any day, so start with finding a social worker; these professionals are there to help you in just this type of situation. Best of luck - PJH

I also had some tenderness, pain and itching since the first clip was placed at my first biopsy. I had a second biopsy in order to enroll in a clinical trial and they placed a second clip. After that the pain and tenderness was much worse. Just yesterday, two and a half weeks after my second biopsy, that scar opened and the second clip came out - my body sent it back through the biopsy path (about 2 cm distance). I'm going to the doctor this week to have them check to make sure there's no infection.
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I can fully relate to you and the others on this site.I had a marker put in with a known collagen and metal allergy.The doctors putting it in lied saying it was just titanium no collagen as I told them I was allergic,vegetarian and kosher.Collagen is from slaughterhouse waste containing all animals and against everything I believe in.I had pain 15 min after and for 2 months.Finally I went to a new hospital and got an Indian doctor who was sympathetic to vegetarians who sent me to a radiologist to remove the thing.I felt better instantly on the table.It still hurts as the collagen soaked in and was not removed all the way and was referred to a plastic surgeon.He will remove the collagen and now ugly scar tissue for $1200.Tips-go to a university hospital and get a Melissa test for titanium allergy as proof or go to a plastic surgeon.Also hospitals in Vancouver Canada will remove it for about $900 CAD.Thailand and Singapore Raffles Hosp.deals w/plastic surgery and allergies and do this for less.

Hello Everyone. I had a breast biopsy a month ago because they said there are some tiny calcifications the size of grains of sand that are getting bigger. The radiologist told me they would insert a small clip in case it is cancer. "You will not feel it", he said. Well, I feel it. I have stabbig pains in certain positions. The good news is that I do not have cancer. I saw a surgeon today and he told me there are two clips in there and the pain is caused by bleeding around the clips. He said that the pain would subside after while but I do not think so. He said that he will take out one. I said we need to take them both out. He said he did not know if he could but he would try. They are deep inside. I do not know what to do because what if one is left in and I still have pain. I would appreciate any advise. The radiologist should have told me that this could happen and let me decide about leavng it in.

Catherine, I'm sorry you're having this pain. The vast majority of women don't have any issue with these clips, but unfortunately, you're not one of them. I'd suggest you get a second opinion from another surgeon before you get the one clip removed; hopefully you can find someone who feels confident s/he can get both out at the same time. Good luck - PJH

I had a biopsy the beginning of November and they put two clips in. I have constant pain and discomfort in the breast. I am have a lot of allergies ~ thus my body is telling me that this is a foreign matter and it does not like it.
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I had a stereotactic biopsy done in July of 2012 and markers put in. I had pain in my breast and a red mark for about 6 months. I went back in July of 2013 and had my yearly mammogram done and did not get a letter that additional films were needed. The next day after that mammogram I got extremely sick. It felt like I was being stabbed in the back and I could not breath. I was sick for 3 days and ended up in the emergency room. They gave me a chest x-ray and an EKG and said I was fine and had acid reflux to stop at a pharmacy and get something for it.

I continued to have pain ending up in the emergency room again where I was told that I had a thoraxic sprain and was having a panic attack because of the pain in my back. I was sent to therapy and had the same thing happen where I was having such sever pain in my back I couldn't do the therapy. They felt they were making things worse and told me to go back to my PCP.

I then had a CT scan and it came back normal. I continued to have pain and was told I had anxiety and was put on medication.

I am now taking 2 anti anxiey meds and hormone replacement.

I then went for a gall bladder test and it wasn't working so they took that out!

I went back in July of 2014 and had my yearly mammogram, it was requested that I go back for more films and a sonogram. I was then told I needed another biopsy. When I got to the hospital the radiologist said he was comfortable with the areas that they were watching were cancer free!! Yeah very happy I didn't need to do anything. He then asked if I had breast surgery in the last 2 years.

I told him I did not why was he asking. He said my markers were not there they had migrated somewhere in my body and asked if I noticed if they had came out through my skin somewhere. REALLY!!

I came home and started researching if anybody else had a problem and found this blog.

I now have to have a second opinion and they will decide if we are going to do another biopsy.

UGH!! I just want someone to listen to me. I was a very healthy woman before I had these things in my body. I am still having this pain I'm just not freaking out about it. Take a Zanax and go to bed! Not the way I want to live my life.

I can't believe that so many women are having a problem and nobody is listening. Can't someone listen to us!!!!!!!!!!

Linda, this is a good forum to post your concerns; at least you have us and your fellow readers listening. I've never heard of a clip migrating out of your breast to another location, but if that's what they surmise happened, I guess it's possible. I'm glad you're not stressing as much as you used to, but it would be great to get rid of the pain, wouldn't it? I hope you can find someone who takes a possible titanium allergy seriously, and can help you do something about it. Good luck - PJH

Ended up paying $4k for a "General Surgeon" to take out the marker, and she didn't! I specifically told her to, as I KNOW that is what the problem is with the severe pain! She just took out scare tissue from the Stereo Biop and said that was the problem. Now, it's worse . . . Ugh.

Following a biopsy 3 years ago at Ann Arundle Hospital in Annapolis, MD., I too have this clip in my breast. It has discolored my breast and is very painful. I am looking into a law suite for the discomfort this has caused me. The Dr. who inserted the clip said "I would never even know it was there, it's only the size of a grain of rice and it's just a marker for your future breast exams to let the doctors know this area has been checked before". Well that was a total lie! I see this a an unnecessary procedure that has caused me extreme discomfort! They should check the entire breast as many times as necessary, therefore having this clip serves no real purpose! Now in order to get this annoying foreign object removed I was told to first contact my primary care provider then I will need to see a surgeon. This is a racket! Now there will be even more hands in the pocket of my health insurance!!! What a mess! We need 20/20 on this!

I know this is an old question, but just wanted to add my two cents... had a stereo biopsy in January and they inserted a clip. I've had breast pain off and on, but it's recently been better - until last night. My daughter gave me a big bear hug and squooshed my right breast and it's been acting up ever since - sensations like something crawling under my skin, itching like crazy, and just a general sense of something not right with it. It's at the site where they put the clip. It's like the bear hug jarred something loose or pushed it into other tissue or something... hard to explain but judging from this thread I'll bet you all know what I'm talking about. I'm worried that this has started something now. I'll keep an eye on it and hopefully it'll calm back down but what a bummer, after all this time, to have it flare up like this! At least I know it's not in my head, though. That's a relief in itself. Thanks for listening. --Vickie

Vickie, that nice big bear hug could very well have pushed the clip so it's touching a nerve; this sounds very much like nerve pain/tingling. Hopefully if this is what it is, either the clip will move again, or the nerve will compensate and get used to it, and the pain and other sensations will stop. Best of luck - I hope you're back to normal soon! PJH

karen i notice the date and was wondering if you had the clip removed? if so was that the problem. iam going to see a surgeon to have my clip removed. i hope that is the answer to the itching and shoulder pain in my left breast that has been going on for five years. pam

Sherry, we don't use our personal email boxes. If you'd like to send me a private message, just click on my nameat the top of this reply - that will take you to a page where you can send a private message. I'll look forward to hearing from you - PJH

I had an MRI that showed suspicious cyst followed by an ultrasound to determine that mass was solid not fluid. During the ultrasound last week I was urged into a core needle biopsy procedure guided by ultrasound performed by the radiologist, although I was asking for and really wanted a lumpectomy. The radiologist also inserted a metal clip for future identification. I am scheduled for a lumpectomy and lymph node biopsy next week, and may end up getting double mastectomy.

I am now (post op 1 week) having pain in my armpit lymph nodes and tingling in wrist and hand, initially on the side of the procedure and now on both sides. What is this? Did radiologist hit a nerve? Is this inflammation? I am worried that biopsy can cause cancer cells to spread, which is why I wanted lumpectomy in the first place.

Annemarie, I'm not a doctor, so I don't know everything that was in the doctor's mind. I can guess that he may not have wanted to do a lumpectomy until he had more information about the nature of the lump. The amount of tissue he would remove might be different for a benign lump than for a malignant one.

You have some post-operative pain that sounds a bit unusual to me. The pain on the side of the biopsy makes sense, but not on the other side. I don't think the marker would have anything to do with this, and it will help the surgeon make sure that he goes back to the proper spot. Call the surgeon's office and report all of your symptoms. Also write down all of your questions so that when you see the doctor to discuss the next steps, you will have them right there. It is a good idea to take someone with you to help you speak up for what you want as you move along with treatment. I don't know if going straight to a lumpectomy was a viable medical option, but it is clear that your doctor did not do an adequate job of explaining his decision-making process. I hope the next steps in treatment go well for you.

I had a marker clip put in my left breast at age 37 when the Navy doctors at Camp Pendleton Naval Hospital did a biopsy. Not only was the operation a total hack job (every doctor who has seen my breast since then has asked if I was stabbed... terrible cut and stiches from the biopsy), but the clip is MUCH larger than what the civilian world was using. That was in 1997. I recently lost weight and as a 52 year old, of course my breast are not perky anymore. So when I get mammograms or my husband is on top of me, I feel like I'm getting stabbed. The clip can be seen on the mammogram very clearly, and looks like an open safety pin! I kid you not!!! The pain has gotten worse over the past few years, and I finally went back to the doctor yesterday. They did another mammogram and said that the clip is too long and probably is "stabbing" me when I sleep on my stomach or even have on a tight bra or just have pressure on it. So they are sending me to a breast surgeon to see about having it removed. I often feel stabbing sharp pains at various times during the day. Then they go to dull pains, like I felt when I was recovering from the original surgery 15 years ago. So my pain and discomfort is different than most of the people posting here. My clip is stabbing me! I hope the insurance will pay to have it taken out. If not, I'll just try and get a loan from the bank. But I can't live with this pain any longer!

Wow! I'm sorry that you have had to live with this for 15 years. Since the clip is clearly not "standard issue" and it is causing pain, your insurance should cover removing it. If they deny the surgery cost, file an appeal. The breast surgeon's recommendation will be the basis of their decision, so if the surgeon thinks it needs to come out, they will probably pay the claim with no fuss.

I had breat biopsy on 1/26/2012. They took three samples out of my right breast and placed three markers in. My breast started to get red and swollen in couple days. I thought it would be a normal reaction to the trauma but it kept swelling and finally liquid started to come out of one of the biopsy points. The surgeon has put me on penicilin. One week after that she sent me back to the radiologist to remove the remaining liquid. Three days after liquid removal I had a lot of blood coming out of my breast. The surgeon told me that none of the liquid samples grew any bacteria. Since penicilin didn't work she put me on cipro and doxycycl. I have asked whether it could be a reaction to the markers but she did not think so. She sent me to a infectious disease specialist which I have just seen today. He says that the cultures and blood results do not show any sign of infection but there is a lot of inflammation. They are not sure what to do, they will discuss this week. I just want to be able to hug my kids again without going through all this pain. Any inputs will be greatly appreciated.

Although redness and swelling can happen after a biopsy or any other surgery, generally the symptoms get better not worse over time. When they do get worse, checking for infection like your doctor did is the usual course of action. Since your doctors are not finding evidence of infection, then other possible causes of inflammation need to be considered. One might be some type of allergic reaction, possibly to the markers, but maybe also to some other product you have used, such as surgical tape, topical medicines, and so forth. One cause of breast swelling and redness following a biopsy can be due to the lymph vessels in the skin of the breast becoming clogged by scar tissue. I read about a study done at the Mayo Clinic in 1997 that found previous breast surgery was the cause of redness and swelling in a small sample of patients even though no cancer or infection was present. Was your biopsy negative for cancer?

If you are have not be seen by a doctor at a comprehensive cancer center or other breast surgeon with expertise in these kinds of complications, you might want to ask for a referral to a comprehensive cancer center or research hospital. It sounds like your current doctors are at a loss about the cause of the problem, and they might well appreciate some input from another doctor.

Thank you so much for your response. Yes, my biopsy was negative for cancer. After going through numerous test and checks, my surgeon now thinks that this is most possibly granulomatous mastitis. She thinks we should start steroid treatment before surgery as surgery does not guarantee that it won't come back. I am terrified of drugs let alone steroids.

I am getting a second opinion at NYU next week. In the meantime, I have this lump that has been growing on top of my breast (right on top of one of the biopsy areas) and now it started to bleed a little (very painfull too).

I have been asking the doctors whether this could be a reaction to the markers. Though they say they don't want to rule it out, I don't hear them talking about removing them as a treatment option.

Even if this is gm, I am not sure why it started to grow right after the biopsy. I am also concerned that it sounds like there is no certain way of treating this condition. Any inputs?

I'm glad you're getting a second opinion - hopefully from a breast specialist? Granulomatous mastitis is a rare diagnosis, and it might be your surgeon is doing some grasping at straws trying to pin down what's causing the inflammation and pain, since it doesn't seem to be an infection. I'd definitely ask the doctor at NYU about having the markers removed; they're there just on the rare possibility that cancer might develop in the area biopsied sometime in the future. In the meantime, if there's ANY chance they're causing your distress - why not get them removed and see if it helps? Good luck with your appointment next week; this all sounds very distressing... PJH

I was not familiar with granulomatous mastitis, so I took a look at a few medical journal articles about it. From what I read this is a rare condition, so seeing the doctor at NYU is an excellent idea. Anytime one has a rare condition, it is important to get to the people with the most expertise in treating it. One of the articles talked about the possibility that granulomatous mastitis is an auto-immune problem, so you might want to consult a rheumatologist as well as breast surgeons. Keep asking about the markers. I don't know if they are connected to your current problem, but it is a question worth asking. We know that reactions to the markers are rare, but so is the diagnosis the doctors are currently considering.

I understand your concerns about drugs, but sometimes that is the best way to treat a problem. Steroids sound particularly scary because of their misuse by some athletes. However, you would be taking the correct dosage under medical supervision. If you have side effects, the dosage could probably be adjusted. I hope that the visit with the doctor at NYU gives you better information.

Thanks for your responses and suggestions-my suspicious findings were from an MRI - to those who face much anxiety know your choices and what you can later live with. A rescan would have been my best option - I was told by the radiologist that I could see a surgeon to have this tag removed - does anyone know of the extent of this surgery - quite invasive ? (I apologize for my somewhat irrational mindset at this point-as these clips have benefitted people too.)

sorry to hear of all the physical symptoms post clip placement- I can not believe radioligist's refuse to due breast biopsys without putting these clips in. Overwhelmed with anxiety by not only the recomm. of having a breast biopsy - but also from the pure anxiety of having a clip left in me. Perhaps one more erason to put in my brain to getting breast ca. My biopsy was done only about a week ago-I think the anxiety is now going to kill me-despite pathology results stating it was benign.

Please keep in mind that adverse reactions to titanium clips, this thread notwithstanding, are extremely rare. And thank goodness, your biopsy showed no cancer. So your goal now is to somehow get your head straight. It's very hard, I know, not to worry. But worry is eviscerating; it does nothing, other than make you feel bad. Please read our post on fear; and please consider speaking with someone who can help you get past this: a social worker at the hospital or, if that doesn't help, a therapist (whom the social worker could refer you to). You need to rid yourself of this extreme anxiety, and move on with your life. Best of luck to you - it's not easy, I know. But you CAN do it... millions of us have faced down fear, and in time, you will have done so, too. PJH

The internet is a blessing. It provides information that helps people get good medical care. It can also cause needless anxiety. It is much too soon for you to know if you will be one of the rare cases where a clip causes a problem. It is going to take a while to heal from the biopsy. If you are still in pain after your incision heals, then this thread could be valuable information about a possible cause that you could investigate with your doctor. But right now you need to expect that your biopsy incision will heal well and that you will remain cancer free. If this anxiety is interfering with your ability to carry out your daily tasks, or if it lasts more than a few days, then talking to a counselor about the source of your anxiety would be a good idea. Of course, most people have some anxiety around a biopsy. It's hard to turn off the "what if" going on in your brain. "What if it had been cancer?" "What if I get this rare problem with the clip?" But you should see less pain and less worry in the days ahead. I'm glad your biopsy was benign.

I was scheduled for a sterotactic biopsy last week, 3 pinpoints of calcification, after hearing that they were going to leave in a 'clip', I decided to reschedule so that I could have time to research it. Thank you all for your personal stories.

I'm writing today to address the 'anxiety' issues that have come up. Please look up "EFT", Emotional Freedom Technique, also known as "Tapping". There are many free resources & it truly works in lessening fear & anxiety.

Thanks for your feedback here - I'm glad you've found something to help you deal with your fear. And I trust you'll come to a resolution about the biopsy that's acceptable to both you and your doctors. Good luck - I hope you get good news. PJH

Thanks for sharing a technique that has helped you. As you research the clips, keep in mind that reactions are rare. People who had the clips and no problems are not likely to write in this discussion. If you have a history of metal allergies or other health issues that might make the clip problematic, a frank discussion with your doctor about the risks and benefits for you specifically would be a good idea. Leaving a marker for the exact area biopsied this time could help avoid future biopsies if this one is benign as we all hope it will be. If you do have cancer, the marker could make a lumpectomy more accurate. I hope all goes well with your biopsy and that the tapping keeps you calm.
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I am also having clip problems but I had titanium placed in my back and was ok with that. I think it could also be the glue as I was highly allergic to the glue on the tape they wrapped my breast in years ago when they took out another lump, which happened to be coagulated clips from my bc surgery!

My breast was oozing and the skin just peeled off. It was the tape.

Now my itching is horrible like everyone elses however I'm not having any pain, just itching.

The fact that my the clips coagulated from my surgery might mean something.

PLEASE DO YOURSELVES A FAVOR AND LOOK INTO MELISA.ORG ....I AM PUTTING THIS IN BIG CAPS AND BOLD FONT SO ALL CAN SEE. IT IS AN ACTUAL BLOOD TEST TO SEE IF YOU ARE ALLERGIC TO TITANIUM, PRONOUNCED "meliza test". I myself did not have breast surgery, but I had my gallbladder removed 9 months ago and have been living a nightmare. I have had many tests done and none can say why, i finally started to look into whether i may be allergic to the titanium cilps they put in me. I know a lot of doctors act like it's a low chance that someone would be allergic to titanium but do not listen, get yourself tested for the allergy. From my reading, a regular patch test done by an allergist will not work, you need an actual blood test. The test is called THE MELISA TEST. I will be doing this in the next week or so. From my understanding there are labs in a few different countries that do the test, in the USA, i have found two. A lady who is a doctor and works with the MELISA organization responded to my email and told me of a lab in South Amboy, New Jersey that does the titanium allergy test (MELISA TEST). I also think there may be one in Wisconsin. I called the lab, had them fax the form to my doctor, he filled it out and faxed it back to them. Now they will be sending me a kit that is safe to ship blood in. I'll go get my blood drawn and then ship it. From my understanding it will cost me 75 dollars to test for the titanium allergy and they claim it'll take about ten days for the results. The lab in New Jersey is ran by a female doctor, so it is nothing shady. It's a certified lab. They also test for other metals, so i am also thinking of testing for stainless steel allergy, because from my readings stainless steel contains nickel, which a lot are allergic to. I'm not sure whether my clips are titanium or stainless steel, but since it's like pulling teeth to find out, I will test both. Please look into this...I wish you all well, things will be better, keep on keeping on....after hurricanes come rainbows...big hugs!!

Thank you so much for this info. I too have had a Marker placed in my left breast in jan 2011. Since then it seems like I have had one infection after another, Bronchitus, Sinus, internal Breast Itching and weakness in all of my body. I just recently commented to my husband how strange my breast feels,sometimes pain,sometimes cold numbness. These posts have been a blessing to me. Thank you all for your info. I rarely look up info like this but thank God I did. I am very disappointed in the insensitivity towards us by the medical field. lUCKILY some Drs. still honor there oath to serve and heal. My prayers are with you all. ps I will look into takeing the MELISA TEST..

Just a quick update to let you all know that I mentioned the marker placed inside of me to my Gyno. She too feels that it is all in my head and it is a coincidence. Since I know my body and I know it is not all in my head I still feel the itching, pain and numbness at diffrent times in side of my breast. I am now over my Bronchitus and pneumonia and I will be seeing another surgeon next tuesday. I will be asking her to remove the clip. Hopefully I can be rid of this and move forward with my recovery. I hope all of you who still have this clip find a way to have it removed soon.

For all you ladies who are suffering from the titanium markers I too have been pressured by doctors that they can't do the biopsy without the marker. I am fixing to be an advocate for women on this issue as I have been to a news reporter in Greenville South Carolina on this subject and have been ignored.I am about to go a step further as I have great concerns for the women suffering as they are this is an outrage it is a violation on our health.Women in torament, who knows maybe they are experimenting on women to see how the body reacts to the titanium maybe they are going to use this metal for the mark of the beast later on. Never the less its a serious issue I need help from anyone who cares to help me address the world about this.--at: (deanandfelicia@facebook.com..or..deanandfelicia@yahoo.com..god bless all !!!!

I know of no evidence that titanium markers are being used by doctors to experiment on women. Titanium is used in a wide variety of medical applications, especially for broken bones and joint replacements. It is generally safe. Some people do have a reaction to it, so if a woman doesn't want her doctor to use a marker in a biopsy, she has the right to refuse it. If she does so, she needs to understand that the doctor may later have trouble finding the exact spot biopsied leading to more extensive follow-up surgery than she would have had with the marker. Another benefit to the marker is that if the biopsy is benign, it allows the radiologist to look at the exact spot biopsied in later mammograms to make sure everything is still OK. Every medical procedure has risks and benefits. There is a tiny risk that a titanium marker will lead to problems, but for most women the benefits are greater than the risks.

I just had my biopsy last August 10, and I wasn;t aware about the negative effects of the procedure since my radiologist and nurse assured me nothing is going to happen to me. After reading all of this I am very scared i thought my nightmare is over. I just really hope it won't cause a negative effect in my body, right now I still have bruises from the procedure and waiting for it to heal. I just hope that nothing is going to happen to me after an excruciating and expensive procedure I've gone throuhg. For those who experienced side effects I will pray for your safety and recovery. Be strong pls. keep in touch with me if you can ziur_nylanoj@yahoo.com

Jona, keep in mind that this is a support list, so people who are having problems are the ones who write in. Reactions to titanium are rare. That is why is is used for reinforcing bone and joint replacements. The amount used for a biopsy marker is much smaller. The thousands and thousands of women who have breast biopsies with no reaction to the titanium have no reason to write in and add to this thread. Your radiologist and nurse are reassuring you because they work with breast biopsy patients every day who do just fine, and probably the worst thing they have to do is tell a woman that the biopsy shows cancer, in which case that marker is going to be invaluable in planning her lumpectomy or mastectomy. I'm sorry that your biopsy was excruciating. All biopsies involve some level of pain, but usually it gets better within a few days. I hope you get good news from the pathology report.

Thank you for your reply, I already knew the result of my biopsy and it's non-cancerous so I am very happy. As of now my left breast is doing well. No adverse effect except the bruise which I think is normal. I am applying hot and cold compress everyday so slowly slowly it changes. My bruise now is starting to change to a lighter bruise. No allergies and itching. It's already the 6th day after the biopsy so I am really fine :) Thank you for the information you posted in this thread it made me feel better and relieved.

I'm so pleased to hear that your biopsy was benign. Although everyone heals at a different rate, your progress sounds typical. As long as the bruising and incision continue to get better, you don't need to worry. If you developed increasing soreness or new redness, it would be time to contact the doctor to get checked out.

Does anyone know the name of a plastic or other type surgeon, or a hospital, where they will remove these titanium clips? My surgeon is no use, she refuses to admit there is any problem. I am in the northeast - I will travel to any reputable dr who will remove this biopsy clip.

I am from the northeast and seeing a breast surgeon on Oct 13 2011...I went to my gyno on Sept 20th and told her that I have been having lots of pain in my left breast...she said that this was NOT Normal and set me up with a surgeon..I told her that I could be doing nothing and I would get a sharp pain like someone was stabbing me with a knife..I have had my marker clip put in a few years ago and I would get twitches here and there with pain..I am also having problem with the transvaginal mesh sling but I am part of a class action suit on that one..I wouldn't be surprise if there was going to be a class action suit on these marker clips..I will let you know what the surgeon said..I am from the Saratoga Springs NY area.

Let us know what you find out from the surgeon. Keep in mind scar tissue from surgery can be painful. I still have pains in several areas where I have scar tissue from previous surgeries and no markers. One of the areas goes back to a surgery in 1992. The surgeon may find that your clip is pressing on a nerve or causing some other type of problem, but please keep an open mind about the cause of your pain.

I am also having clip problems but I had titanium placed in my back and was ok with that. I think it could also be the glue as I was highly allergic to the glue on the tape they wrapped my breast in years ago when they took out another lump, which happened to be coagulated clips from my bc surgery!

My breast was oozing and the skin just peeled off. It was the tape.

Now my itching is horrible like everyone elses however I'm not having any pain, just itching.

The fact that my the clips coagulated from my surgery might mean something.

Thanks for sharing your experience, which is a good example of how complex medical issues can be. The itching sounds like it might be allergic in nature. You don't mention how long you have had it. It can be several weeks (or longer) for healing to occur after a biopsy. If it is getting worse, please go back to the doctor and get checked out to make sure you are not getting an infection. Either way, ask the doctor about the best product to try to help the itching. Some of the over-the-counter products shouldn't be used over large areas of skin or for a long time.

Thank you all so much for sharing your experiences. I had a biopsy done today, and refused to let them place the marker. My mother's good friend had one placed two years ago, and has had severe pain and itching ever since. Thank goodness my mom told me about this. I had made up my mind not to let them put it in, and after a few minutes of argument from the doctor, she finallly gave up. She seemed very annoyed at my non-compliance, but afterward, the ultra-sound technician agreed that it was my body and my choice. I was wondering this afternoon if I'd made the right decision, and your testimonials confirm for me that I did. I hope you all find relief soon and enjoy good health!

Dawn, best of luck to you - about 85% of breast biopsies are negative, and I hope you fall into that group. Please read our post on biopsies - I think you'll find the information helpful. Take care - PJH

I felt pain when the anesthesia wore off, so fill any prescription for pain killers that they give you before you need them. Both my biopsies were extensive. The first was benign, and the second one showed cancer. I was fine in a day or two from both. Everyone will be different depending on the location of the biopsy, how much tissue the doctor takes, and the patient's own pain tolerance and speed of healing. I hope all goes well with your biopsy and that you get a good report.

Hi All-I was given a marker at the time of my biopsy. I was not asked, I was told what was being done. I was 63 at the time. I did not give it much thought until I spoke to my stepdaughter who told me that she has had pain her breast where a marker was placed. She said the pain increases during her menstural cycle. She told her twin sister not to have the marker put in but the hospital insisted she do so at the time of her biopsy. I thought I was imagining the itching until my husband suggested to try to find out how others fared. I am furious that no option was given nor were any side effects discussed. What kind of nonsense is this? Women are being told that their pain and itching is in their heads? Interestingly enough, I had radiation for uteran cancer. I was told there were literally no side effects. Funny, weeks after completing the treatment I experienced numbness in my pubic area and inner thighs. Going on line regarding this issue resulted in finding other women with similiar and/or more severe side effects. I cannot wait to see my radiologist and the breast surgeon who did my biopsy! Ladies thanks for sharing...I have always said that without other women to talk with we would be in a heap of trouble. M

Thanks for sharing your experience here. For sure, doctors don't know/can't predict all the side effects we experience - sometimes I think we each have our own personal ones! If you haven't already, please take a look at our post on titanium markers - you might find it interesting. Cheers- PJH

I am online like yourself attempting to find information on the Bard Ultraclip II - Titanium Marker. Do they not hear the cries of the many womany begging for help. Recently I had a biopsy done and they placed one of the titanium markers in my mass. I immediately had severe pain and was dismissed over and over again. All the while my entire body is breaking out in severe hives and my body is starting to shut down. I attempted to get anyone to listen to me as I know when my body is having a reaction. Well let me tell all the women on this site. Please inform yourself prior to having this clip placed in your body. IT IS VERY DANGEROUS! They almost killed me. The only reason they removed it from my body is I ended up in a surgeons office who had to addmit me for emergency surgery last Friday due to the fact that my heart was slowed down to a pulse of 38 and the breathing was shutting off. I agree with you these medical supposed professionals need to take notice there is a problem here. We need to find a way to ban together and get something done. No person and No woman should ever be made to feel like garbage or like they are going crazy again. I do not want to wait until someone is dead to say I should have made my voice loud.

OMG. This is absolutely amazing... I never thought of looking this question up... I had a Clip put in around 2000. Ever Since then, I get excruciating Pain in that One Breast. It puts me in tears, it hurts so bad. It almost makes me think I am about to have a Heart Attack.... I also complained about this to my doctor and he said Oh no, thats not the cause of your breast hurting... But I know it is.... I can rub that certain spot and the pain goes away for a little bit ... It doesnt hurt everyday either... WOW... I cant believe all the women who have had this procedure and are hurting like this..... This just amazes me.....

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