I was just curious to know how different are the Pokémon games on M3i compared to the original cards ?

I'm a happy owner of an M3i Zero and was wondering...
Is there anything -beside the PokéWalker for the upcoming ones, of course- that doesn't work on M3i version ?
Like Wi-Fi connections, wireless, ect....

I don't know a lot about these games and what other options they offer.