Epigenetics Now Goes Far Beyond HDAC Inhibitors

By Anette BreindlScience Editor

Monday, April 8, 2013

WASHINGTON – Several presentations at the American Association for Cancer Research's (AACR) Annual Meeting this week underscored the size of the epigenetic space. Targeting epigenetic alterations has gone far beyond histone deacetylase (HDAC) and DNA methyltransferase (DNMT) inhibitors, which are the two classes of epigenetic enzymes that have approved drugs targeting them.