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Tiny Dancers

Could observation of waltzing therapeutic nanoparticles help determine drug efficacy?

By nature, the process of drug delivery is sensitive. The binding of a ligand at a cell receptor is akin to a dancer selecting a partner. A fine-tuned affinity is required for the partnership to work; binding that is too strong or weak can result in a failed interaction. The successful delivery of immunotherapies is a constant challenge, as is the ability to detect ligand-receptor interactions at a high resolution when trying to select the most effective immunotherapies.

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