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Major side effects of amiodarone. Authors Elsa-Grace Giardina, MD, MS, FACC, FACP, FAHA. Elsa-Grace Giardina, MD, MS, FACC, FACP, FAHA. (200 to 300 mg/day).Metronidazole: beware of neurotoxic side effects: Metronidazole, a `classic` drug in canine medicine, is currently very popular to treat a variety of diseases.