The investigators want to determine if the benefits of weight loss outweigh the potential risk in a group of older adults. The investigators will test the hypothesis that changes in diet composition alone or in conjunction with weight loss will have a significant effect on fat stores, and as a result, improve cardiometabolic risk factors and functional status in adults 65 and older.

history of prior surgical procedures for weight control or liposuction

use of estrogen or testosterone replacement therapy

current use of insulin or sulfonylurea agents

current use of corticosteroids > 5 days/month on average

current use of medications for treatment of psychosis or manic-depressive illness

use of weight-loss medications in previous 3 months

dependence on others for food procurement or preparation

ischemic changes on exercise treadmill test

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00955903