The MacBook Pro has two Thunderbolt 3 controllers, one on each side. Each Thunderbolt 3 controller takes two DisplayPort inputs from the GPU of the MacBook Pro. Both DisplayPort signals can be transmitted down a single Thunderbolt 3 cable.

Each LG UltraFine 5K display requires two DisplayPort signals over Thunderbolt to support 5K 60Hz resolution. This is why each LG UltraFine 5K requires a separate Thunderbolt controller (one on each side of the MacBook Pro). The Thunderbolt controller in the LG UltraFine 5K uses both DisplayPort signals, that is why it does not have a second Thunderbolt 3 port to daisy chain other Thunderbolt devices.

The Blackmagic eGPU has a Thunderbolt 3 controller which takes two DisplayPort inputs from the GPU of the BlackMagic eGPU. Both DisplayPort signals can be transmitted down a single Thunderbolt 3 cable.

Because the GPU of the Blackmagic eGPU is separate from the MacBook Pro GPU, and because the LG UltraFine 5K connected to the Blackmagic GPU takes DisplayPort signals from the GPU of the Blackmagic eGPU, there will be no conflict. This is not possible with other eGPU solutions unless you have a Thunderbolt 3 add-in card (with DisplayPort inputs) between the Thunderbolt display and the GPU of the eGPU.

If the OS doesn't allow it, then that's a bug that should be reported.

The displays connected to the MacBook Pro will not be accelerated like the display connected to the Blackmagic eGPU. They might see some improvement, depending on the software.

I own a 2016 13" MacbookPro and the LG 5k display. Typically I use it for programming (VSCode, XCode etc.), occasional light gaming. Drawn to this product as it works with the display and would make a decent desktop dock with its extra ports and power.

I do notice windows get a bit choppy on the 5k display, so I'm curious the benefits that this eGPU will bring - essentially will it be enough to notice in my every day? Benchmarks seem to focus on either heavy 3D games or video rendering.

Yes. The choppiness comes from tearing and stuttering because your internal integrated GPU is way to weak to export 5k video at 60hz. however I would suggest using the pro version of this egpu with a Vega 56 for great performance on a 5k monitor

Will it help free up processing for running more plugins or adding track counts since it will be handling most of the graphics load? ...Or, maybe if running multiple external monitors while editing? Thanks in advance!