VEHICLE TO VEHICLE WIRELESS CONTROL SYSTEM TRAINING - A system for mounting to a first vehicle and for learning information from a first transmitter configured to be mounted to a second vehicle. The first transmitter is further configured to cause the activation of a remote device by transmitting a first control signal to the remote device. The system includes a receiver and processing electronics coupled to the receiver and configured to increase the sensitivity of the receiver. Increasing the sensitivity of the receiver is based on the receipt of a first command that indicates that the information will be communicated from the first transmitter. The receiver with increased sensitivity is configured to receive the information from the first transmitter. The processing electronics are configured to used the received information to determine signal characteristics. The system further includes a memory coupled to the processing electronics and configured to store the signal characteristics, and a second transmitter coupled to the processing electronics. The second transmitter is configured to receive a second command from the processing electronics to generate and transmit a second control signal based on the stored signal characteristics. The second control signal is transmitted to the remote device to cause the activation of the remote device.

2010-08-19

20100210232

CONTROLLING X-WAY RECEIVER DIVERSITY - Method for controlling receiver diversity operation in a base station of a mobile telecommunications network, the base station comprising a first receiver arrangement and a second receiver arrangement, the method comprising:

2010-08-19

20100210235

METHOD AND APPARATUS FOR RECEIVER DIVERSITY CONTROL IN WIRELESS COMMUNICATIONS - Receiver diversity in a wireless device is controlled in response to operating conditions, transmission requirements, and control settings. The control of diversity reduces power consumption by enabling receive diversity on given conditions. Operating conditions, transmission requirements, and control settings are used separately or used in conjunction to determine whether benefits of multi-antenna receive diversity, such as higher link capacity, higher data throughput, lower transmit power, and lower error rate, warrant the higher power cost of the diversity.

METHOD AND SYSTEM FOR COMPLETING A ZONE RELATED CALL - A method and system, for completing a call to a mobile subscriber having one or more zones defined, where the calling party is presented options for call completion based on the distance and direction of the called mobile subscriber in relation to his zones and presence inside a perimeter around his zone. The call completion comprising; call back, notification by SMS or notification by voice message on entry or exit of the area enclosed by the perimeter, or connect with additional charges for the calling party.

2010-08-19

20100210261

METHOD FOR ENSURING THE ACCESSIBILITY OF MOBILE RADIO DEVICES USING AN OPTIMIZED PAGING MECHANISM - The invention relates to a method for performing a paging call in a cellular mobile communications system, wherein a terminal device is operated in a first radio cell of the mobile communications system provided with radio signals from a radio transmission device, said terminal device being in an idle state, and data to be transmitted to the terminal device are present in a data transmission device of the mobile communications system. The invention is characterized in that upon detection of a loss of service or fault in the radio transmission device, measures for handling the loss of service/fault in said radio transmission device are taken, with the goal of restoring the accessibility of the mobile radio device for which said radio transmission device is the last known radio transmission device.

2010-08-19

20100210268

HANDOVER METHOD AND APPARATUS IN A WIRELESS COMMUNICATION SYSTEM INCLUDING FEMTO CELLS - A handover method and apparatus for facilitating a handover of a user equipment to a femto cell in a wireless communication system supporting both the femto and macro cells. When a handover condition is detected, the user equipment acquires identity information of a target femto cell base station from system information transmitted by the target femto cell base station, decides whether to handover to the target femto cell base station, based on the identity information; and transmits a measurement report message including the identity information to a serving base station of the user equipment, when the handover is to be made.

2010-08-19

20100210279

Dynamic Reconfiguration of Communication Resources in a Multi-Transceiver Configuration - A system and method that provide dynamic reconfiguration of communication resources in a multi-transceiver configuration. Various aspects of the present invention may comprise communicating a first portion of a first communication using a plurality of transceivers. A determination may be made to reallocate at least one of the plurality of transceivers for a second communication. A second portion of the first communication may be communicated using the plurality of transceivers less the reallocated transceiver(s), and the second communication may be communicated using at least the reallocated transceiver(s). Various aspects of the present invention may also comprise communicating a first communication utilizing a first transceiver and a second communication utilizing a second transceiver. A determination may be made to utilize the first and second transceivers in a MIMO configuration to communicate next information. The next information may then be communicated utilizing the first and second transceivers in a MIMO configuration.

2010-08-19

20100210286

Location services interworking with intelligent network - The invention provides location information indicating the geographical location of a mobile station via a core net-work node serving the mobile station The method includes the steps of initiating a communication between the mobile station and the network by calculating the geographical location, supplying corresponding location information indicating the geographical location to the core network node, and subsequently routing the communication between the mobile station and the network.

2010-08-19

20100210298

SOUND-GENERATION ARRANGEMENTS IN PORTABLE ELECTRONIC DEVICES - A mobile electronic device is provided. The mobile electronic device includes a housing having an ear-facing surface. Also, the mobile electronic device includes an audio transducer disposed within the housing. Further, the mobile electronic device includes an acoustic channel coupled between the audio transducer and the ear-facing surface for transmitting sound waves produced by the audio transducer to external of the ear-facing surface, wherein the audio-transducer having an audio-transmitting plane disposed at an angle other than parallel relative to the ear-facing surface.

2010-08-19

20100210310

PORTABLE TERMINAL - There has been a problem that a portable telephone grows larger its size by the volume of a space for improving its acoustic characteristics. Then, a portable terminal includes upper casing

2010-08-19

20100210321

Using Receive Diversity to Extend Standby Time in QPCH Mode - The standby time of a CDMA cell phone is extended by using two receive chains to monitor the Quick Paging Channel (QPCH) when the signal-to-noise ratio falls within a predetermined range. Monitoring the QPCH saves battery power by obviating the need to monitor the general paging message unless quick paging (PI) bits are set. The QPCH is not monitored, however, in noisy environments where PI bits are incorrectly detected causing the paging message to be needlessly monitored. Power is saved by monitoring the QPCH in noisier environments without increasing the incorrect detection rate. Incorrect detection is reduced in the predetermined range by using an additional receive chain to achieve receive diversity. Although additional power is consumed by the second receive chain in the predetermined range, the power saved by not demodulating the paging message at each slot more than compensates for the additional power consumed by the second receive chain.

2010-08-19

20100210327

Audio driver housing with expandable chamber for portable communication devices - A portable communication device includes an audio driver movable within an audio driver housing which forms an expandable chamber. The portable communication device includes at least two portions that are moveably connected to each other allowing the device to be in at least a closed position and an open position. The audio driver can be maintained in a compressed position when the portable communication device is in an open position. Accordingly, the volume of the chamber is independent of the relative position between the portions forming the portable communication device.

2010-08-19

20100210337

Game System Including Slot Machines And Game Control Method Thereof - A game system for playing a basic game, includes: slot machines which, when a combination of “BONUS” symbols stop in a winning line, transmit a signal for switching to a roulette game; a second game device, separate from the slot machines, which executes a second game; and a display for displaying an image corresponding to game status of the second game device. In cases in which the switching signal has been transmitted from any one of the slot machines, other slot machines enter a mode that allows the players at the other slot machines to participate in the second game. Furthermore, the game system includes a central controller which can communicate with the slot machines, the second game device, and the display, and which, upon reception of the switching signal from the slot machine, transmits a roulette game start signal to start the roulette game in the second game device.

2010-08-19

20100210338

METHOD FOR PLAYING A VIDEO GAMING MACHINE - A method for playing video gambling games whereby pay tables vary from play to play, or, alternatively, whereby a plurality of pay tables are possible within a game. For example, in a video poker game a player wagers against a first pay table. If a winner occurs, the next game offers a new pay table with a greater expected value. This process continues until the player loses, whereupon the player is returned to play against the first pay table. Pay tables increment and decrement in expected value based on achieving predetermined events within the current game, within a previous game or games or randomly.

2010-08-19

20100210341

METHOD OF GAMING, A GAME CONTROLLER AND A GAMING SYSTEM - A method of gaming comprising: (a) defining a target outcome to be achieved in respect of a game, the target outcome having an associated award; (b) allocating a number of game rounds to achieve the target outcome; (c) conducting the allocated game rounds, each of which can result in a contribution to the target outcome; (d) accumulating any contributions during the one or game rounds; and (e) making the associated award if the target outcome is achieved based on the accumulated contributions before the allocated game rounds are exhausted.

2010-08-19

20100210352

ACCESSING WAGERING GAME SERVICES BY AIMING HANDHELD DEVICE AT EXTERNAL DEVICE - A portable wagering game machine includes a signal receiver and motion sensors. The signal receiver receives signals from a signal emission device that are used to determine the position and orientation of the portable wagering game machine relative to a gaming establishment devices and locations. The position and orientation information may be used to determine a gaming establishment device or location aimed at by the portable wagering game machine. The portable wagering game machine may then access or interact with a service associated with the device or location, or interact with the device itself.

2010-08-19

20100210358

MODIFICATION OF IMAGES FROM A USER'S ALBUM FOR SPOT-THE-DIFFERENCES - A computer implemented system and method for generating a game, such as spot-the-difference are provided. The method includes receiving a user-selected original image and storing the image in memory. From the original image, the method includes automatically generating a pair of images which are visually identical except for a predetermined number of random localized modifications, and providing the pair of images to the user as a game which can be played by spotting differences between the pair of images as a result of the modifications.

2010-08-19

20100210369

WHEEL BEARING DEVICE AND MANUFACTURING METHOD THEREFOR - A wheel bearing device of the invention includes a flanged shaft member that includes a shaft portion to which a rolling bearing is assembled, a fitting shaft portion that is formed on one end side of the shaft portion and that is fitted to a center hole of a wheel, and a plurality of flange portions that extend radially outward on an outer peripheral surface located between the shaft portion and the fitting shaft portion and each of which has a bolt hole in which a hub bolt for fastening the wheel is arranged. Each flange portion is formed by side extrusion when a forged recess is formed at a center of an end surface of the fitting shaft portion by cold forging.

2010-08-19

20100210375

GOLF CLUB HEAD - In one embodiment, a golf club head can include a golf club face comprising two or more grooves. A first cross section of a first region of a first end of a first groove of the two or more grooves is taken perpendicular to an edge of a sidewall of the first region of the first end, and a second cross section of a second region of the first end is taken perpendicular to an edge of a sidewall of the second region of the first end, and the first cross section is substantially proportional to the second cross section, and each of the first and second cross sections are symmetric. A third cross section of the first region of the first end is taken perpendicular to a bottom of the first region of the first end, and a fourth cross section of the second region of the first end is taken perpendicular to a bottom of the second region of the first end, and the third cross section is substantially non-proportional to the fourth cross section, and each of the third and fourth cross sections are symmetric. Other embodiments are described herein.

2010-08-19

20100210376

LONG LASTING GOLF TEE - A long lasting golf tee for use when striking a golf ball with a golf club. The long lasting golf tee includes a shank having a ground insertion tip at one end and a golf ball support structure at the other end, the shank formed of a member selected from the group consisting of aluminum and its physical equivalents for the intended purpose; an enlargement positioned so as to encircle the shank below the golf ball support structure and located so as to be struck by a clubface of a golf club after the golf ball has been struck from the golf ball support structure, the enlargement having a diameter and a thickness; wherein the diameter of the enlargement is larger than that of the golf ball support structure and smaller than the diameter of the golf ball, the thickness of the enlargement along the shank being less than the diameter; the enlargement being substantially elastic and having a resistance to compression sufficient to prevent the clubface of the golf club from impacting the golf ball support structure. A method of making a long lasting golf tee is also provided.

2010-08-19

20100210391

PLANETARY DRIVE SERVO ACTUATOR - A planetary drive servo actuator comprises a drive assembly operable to turn an output shaft. The drive assembly includes an outer cylinder configured to rotate within the housing and an inner cylinder configured to rotate within the outer cylinder. A clutch is operable to prevent the outer cylinder from rotating within the housing and to allow the inner cylinder to be rotated within the outer cylinder to turn the output shaft.

2010-08-19

20100210409

HYBRID DRIVE TRAIN - A hybrid powertrain of a motor vehicle, especially of a mobile machine having an internal combustion engine and an electric motor, the powertrain also having a hydraulic machine.

HANDLE-MOUNTED PARKING BRAKE DEVICE FOR AN ENGINE-POWERED WHEELED VEHICLE - A handle-mounted parking brake device includes a parking brake lever movable between a first position, where a brake unit is disposed at a non-braking position for permitting rotation of a wheel axle of a vehicle, and a second position, where the brake unit is disposed at a braking position, and a cutoff switch having a mechanical switch body displaceable with movement of the parking brake lever between switch-on and switch-off positions, where a condenser discharge ignition is powered by and cut off from a DC power supply, respectively. Premature activation of a starter motor can be avoided to ensure cutoff of an engine when the vehicle is in a parking brake state so as to reliably prevent inadvertent operation to drive the vehicle.

2010-08-19

20100210424

SWINGING GYMNASTIC MACHINE - A swinging gymnastic machine includes a front swinging assembly, a rear swinging assembly, a handle assembly pivotally secured to the front swinging assembly, and a pedal assembly pivotally secured to the rear swinging assembly. Each of the front and rear swinging assemblies has a spring unit. The front and rear swinging assemblies are durable and are unsusceptible of deflection. The swinging gymnastic machine also has the benefit of reducing the occupied space when it is not in use as both a front leg and the handle assembly are adapted to be folded rearwardly. A person has to exert a great force to overcome the resistance of both the front and rear swinging assemblies through the arms and calves in order to effectively exercise.

2010-08-19

20100210429

RESISTANCE APPARATUS FOR A WAIST-TWISTING EXERCISER - A resistance apparatus for a waist-twisting exerciser wherein the resistance apparatus includes a spring and an adjuster with a pulley block. The adjuster is mounted on a swing element while the spring is fixed at a proper position of the swing element such that the spring is correctly engaged into the pulley block of the adjuster. In applying force to the swing element in motion, the spring may be pulled to create an effective exercise resistance force for increasing the exercise effect. Moreover, the position of the adjuster is adjustable for changing the tension of the spring.

2010-08-19

20100210435

ADAPTABLE FOAM ROLLER - A composite paint roller is provided for improving ease of cleaning, manufacture and adaptability of the same. The roller comprises an elongate cylindrical core, a sheath, and first and second end caps. The sheath is removably mountable about and frictionally engageable to the core. The core defines a core length and opposing open ends. The sheath defines an axial length and opposing sheath ends. The axial length of the sheath is greater than the core length with the opposing sheath ends being foldable and axially insertable into the opposing open ends to produce a radial compression of the sheath adjacent the opposing open ends. The radial compression creates opposing beveled ends of the roller. The first and second end caps each are attachable to the opposing open ends to secure the opposing sheath ends within the opposing open ends.

Catalytic Materials for Fabricating Nanostructures - Nano-catalysts that have utility for forming nanostructures and manufacturing nanomaterials are described. In some embodiments the nano-catalyst is formed from a powder-based substrate material and is some embodiments the nano-catalyst is formed from a solid-based substrate material. In some embodiments the substrate material may include metal, ceramic, or silicon or another metalloid. The nano-catalysts typically have metal nanoparticles disposed adjacent the surface of the substrate material. Methods of forming the nano-catalysts are disclosed. The methods typically include functionalizing the surface of the substrate material with a chelating agent, such as a chemical having dissociated carboxyl functional groups (—COO), that provides an enhanced affinity for metal ions. The functionalized substrate surface may then be exposed to a chemical solution that contains metal ions. The metal ions are then bound to the substrate material and may then be reduced, such as by a stream of gas that includes hydrogen, to form metal nanoparticles adjacent the surface of the substrate.

MAKE AND USE OF SURFACE MOLECULES OF VARIED DENSITIES - The present invention relates to quantitative and quantity aspects of array synthesis and array uses as a device for high capacity producing synthetic molecules for off-array surface applications and as an assay device for on-array surface applications.

2010-08-19

20100210496

Fragrance Effect of Perfume Esters - Adhesion of perfume esters to surfaces, such as the surfaces of textiles, of hard objects, or of the human body, was able to be improved. Said object is achieved substantially by using particular enzymes leading to improved fixing of the perfume ester on hard and/or soft surfaces.

2010-08-19

20100210504

ENHANCED TRANSPORT USING MEMBRANE DISRUPTIVE AGENTS - Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are described. The compositions include a membrane barrier transport enhancing agent and are usually administered in combination with an enhancer and/or exposure to stimuli to effect disruption or altered permeability, transport or release. In a preferred embodiment, the compositions include compounds which disrupt endosomal membranes in response to the low pH in the endosomes but which are relatively inactive toward cell membranes (at physiologic pH, but can become active toward cell membranes if the environment is acidified below ca. pH 6.8), coupled directly or indirectly to a therapeutic or diagnostic agent. Other disruptive agents can also be used, responsive to stimuli and/or enhancers other than pH, such as light, electrical stimuli, electromagnetic stimuli, ultrasound, temperature, or combinations thereof. The compounds can be coupled by ionic, covalent or H bonds to an agent to be delivered or to a ligand which forms a complex with the agent to be delivered. Agents to be delivered can be therapeutic and/or diagnostic agents. Treatments which enhance delivery such as ultrasound, iontopheresis, and/or electrophereis can also be used with the disrupting agents.

MODULATION OF ACTIVITY OF PRONEUROTROPHINS - The present invention provides agents for inhibiting binding of a pro-neurotrophin to a Vps10p-domain receptor, in particular the binding of a pro-NGF or a pro-BDNF to a Sortilin receptor. The invention thus provides agents for the manufacture of a medicament, for treating and/or preventing disease or disorders such as but not limited to neurological, neuropsychiatric and ocular diseases, disorders, and degeneration as well as obesity, diabetes, pain and/or nociception in an individual.

2010-08-19

20100210524

NOVEL ESTROGEN RECEPTOR LIGANDS - The invention provides a compound of formula (I) or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt, wherein W, X, Y, Z, R

2010-08-19

20100210536

USE OF LEPTIN (22-56 ) AS A THERAPEUTIC AGENT - The present invention is directed to the use of the peptide compound Val-Pro-Ile-Gln-Lys-Val-Gln-Asp-Asp-Thr-Lys-Thr-Leu-Ile-Lys-Thr-Ile-Val-Thr-Arg-Ile-Asn-Asp-Ile-Ser-His-Thr-Gln-Ser-Val-Ser-Ser-Lys-Gln-Lys-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Val-Pro-Ile-Gln-Lys-Val-Gln-Asp-Asp-Thr-Lys-Thr-Leu-Ile-Lys-Thr-Ile-Val-Thr-Arg-Ile-Asn-Asp-Ile-Ser-His-Thr-Gln-Ser-Val-Ser-Ser-Lys-Gln-Lys-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.

2010-08-19

20100210537

USE OF A DEFENSIN PEPTIDE AS A THERAPEUTIC AGENT - The present invention is directed to the use of the peptide compound Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquide buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-AIa-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.

TRAP-14 AS A THERAPEUTIC AGENT - The present invention is directed to the use of the peptide compound Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pm-Phe-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.

2010-08-19

20100210576

POLYENE DIESTER ANTIBIOTICS - The present invention discloses a new polyene diester and its preparation. This polyene diester has a structure of Formula 1, which is used as prodrugs by introducing diester group to polyene antibiotics, and these prodrugs exhibit antifungal or antiviral activities through releasing parent polyenes by esterase in vivo. The new derivatives have good antimicrobial activity and better safety. These new derivatives are useful for the antifungal and antiviral treatment. PA-COOR Formula 1

COMPOSITIONS AND METHODS FOR ENHANCING CORTICOSTEROID DELIVERY - The present invention comprises a composition, method of enhancing potency and method of delivering corticosteroids in a vehicle comprising at least two penetration enhancers, and solvents and emulsifiers. The propylene glycol and penetration enhancers are present in ratio to the total of the propylene glycol, penetration enhancers, and solvents and emulsifiers of at least about 0.70.

2010-08-19

20100210610

Organic compounds - There are provided according to the invention compounds of formula (I), in free or salt form, wherein R

2010-08-19

20100210616

METAL COMPLEXES INCORPORATED WITHIN BIODEGRADABLE NANOPARTICLES AND THEIR USE - Compounds for antimicrobial applications, and for treating bacterial and fungal infection are set forth. The compounds may include a metal complex incorporated into a biodegradable polymeric nanoparticle. Also, a method of treating bacterial and fungal infections in a mammal includes the steps of administering an effective amount of a silver(I) metal salt incorporated into a biodegradable polymeric nanoparticle.

2010-08-19

20100210628

NOVEL sEH INHIBITORS AND THEIR USE - The invention is directed to novel sEH inhibitors and their use in the treatment of diseases mediated by the sEH enzyme. Specifically, the invention is directed to compounds according to Formula I:

ISOXAZOLE-ISOXAZOLES AND ISOXAZOLE-ISOTHIAZOLES - The present invention is concerned with isoxazole-isoxazoles and isoxazole-isothiazoles of formula I, having affinity and selectivity for GABA A α5 receptor, their manufacture, pharmaceutical compositions containing them and their use as cognitive enhancers or for the therapeutic and/or prophylactic treatment of cognitive disorders like Alzheimer's disease.

2010-08-19

20100210653

Novel Compounds, Their Preparations and Use - Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the treatment and/or prevention of conditions mediated by Peroxisome proliferator-activated receptors (PPAR), in particular the PPARδ suptype.

AQUEOUS PHARMACEUTICAL COMPOSITION - The present invention relates to an aqueous pharmaceutical composition comprising 1-(2-dimethylaminoethyl)-3-((2R,4aS,5R,10bS)-5-phenyl-9-trifluoromethyl-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-ylmethyl)urea as active compound, to a liquid pharmaceutical composition which is suitable for the preparation of the aqueous pharmaceutical composition, and to a process for the preparation of the compositions.

REGENERATION AND SURVIVAL OF CARDIAC PROGENITORS AND CARDIOMYOCYTES WITH A STRETCH ACTIVATED TRANSCRIPTION FACTOR - The present invention relates generally to the field of cardiovascular repair, and more particularly to methods and compositions for the survival of cells in response to mechanical stress and to the proliferation of postnatal cardiomyocytes. The present invention relates to a nuclear form of Creb312(N) polypeptide which when expressed in a cell promotes cell survival in response to stress such as mechanical stretch stress. Another aspect of the invention relates to the expression of the nuclear form of Creb312(N) polypeptide in a cardiomyocyte promotes propagation or regeneration of the cardiomyocyte. Other aspect relates to methods and compositions for gene therapy for the treatment of cardiac diseases and disorders in a subject comprising increasing the expression of Creb312(N) polypeptide in cells in vivo or ex vivo, such as cardiac cells and cardiac progenitor cells, and in some embodiments, subsequent transplantation of the Creb312 expressing cells into a subject for the treatment of cardiac diseases and disorders in the subject.

2010-08-19

20100210719

O-DESMETHYLVENLAFAXINE - Processes for preparing desvenlafaxine and stable amorphous O-desmethylvenlafaxine succinate solid dispersions with one or more pharmaceutically acceptable carriers.

2010-08-19

20100210724

Method for modifying the properties of an aqueous suspension - A method for modifying the properties of a suspension of solid or liquid particles in an aqueous medium, includes the step of adding to the suspension or to the aqueous medium a polymer prepared by inverse emulsion polymerization of monomers A

2010-08-19

20100210732

Methods of Preventing the Serotonin Syndrome and Compositions for Use Therefor - The present invention is directed to pharmaceutical compositions and the use thereof for preventing or minimizing the intensity of the serotonin syndrome. The present invention is directed at a method of preventing or minimizing the intensity of the serotonin syndrome in humans which comprises administering proserotonergic agents and serotonin surge protectors, wherein said concurrent administration reduces or prevents serotonin excess, which is the cause of the serotonin syndrome. The present invention is also directed to pharmaceutical compositions comprising proserotonergic agents and serotonin surge protectors useful for carrying out the method of the present invention.

2010-08-19

20100210741

COBALT-MOLYBDENUM SULFIDE CATALYST MATERIALS AND METHODS FOR STABLE ALCOHOL PRODUCTION FROM SYNGAS - The present invention provides methods and compositions for the chemical conversion of syngas to alcohols. The invention includes catalyst compositions, methods of making the catalysts, and methods of using the catalysts including techniques to maintain catalyst stability. Certain embodiments teach compositions for catalyzing the conversion of syngas into products comprising at least one C

2010-08-19

20100210748

REACTIVE POLYURETHANE COMPOSITIONS - The present invention relates to reactive polyurethane compositions having only small amounts of free, low molecular weight diisocyanates before and after crosslinking, and to the production thereof and the use thereof in reactive one- and two-component adhesives/sealants, bonding foams, encapsulating compounds and in flexible, rigid and integral foams.

2010-08-19

20100210759

Adhesive Compositions, Micro-fluid Ejection Devices and Methods for Attaching Mirco-Fluid Ejection Heads - Adhesive compositions, micro-fluid ejection devices, and methods for attaching micro-fluid ejection heads to devices. One such adhesive composition is provided for use in attaching a micro-fluid ejection head to a device, such as to reduce chip bowing and/or to decrease chip fragility upon curing of the adhesive. Such an exemplary composition may include one having from about 50.0 to about 95.0 percent by weight of at least one cross-linkable resin selected from the group consisting of epoxy resins, siloxane resins, urethane resins, and functionalized olefin resins; from about 0.1 to about 25.0 percent by weight of at least one thermal curative agent; and from about 0.0 to about 30.0 percent by weight filler, and exhibit a relatively low shear modulus upon curing (e.g., less than about 10.0 MPa at 25° C.).

2010-08-19

20100210761

LIQUID ADMIXTURE COMPOSITION - An admixture comprises an aqueous composition of a) a copolymeric dispersing component, b) an antifoaming agent component, c) a surfactant component, and d) water. The components may be a blend or physically or chemically attached and result in a stable liquid system that can be used as a dispersing agent for a calcium sulfate compound containing construction chemicals composition.

2010-08-19

20100210769

CURABLE FLUORINE-CONTAINING POLYMER COMPOSITION - There is provided a curable fluorine-containing polymer composition which is rapidly cured at relatively low temperature by hydrosilylation reaction to form a coating film having not only high hardness and flexibility but also water- and oil-repellency, thereby giving stain-proofing effect for a long period of time, especially maintaining property of removing and wiping-off stain. The curable fluorine-containing polymer composition comprises a fluorine-containing polymer comprising a fluorinated ethylenic monomer unit and an un-fluorinated ethylenic monomer unit, in which a part or the whole of the un-fluorinated ethylenic monomer units are units represented by the formula:

SLURRY PHASE POLYMERISATION PROCESS - Process for producing a multimodal polyethylene in at least two reactors connected in series, in which 20-80 wt % of a high molecular weight (HMW) polymer is made in suspension in a first reactor and 20-80 wt % of a low molecular weight (LMW) polymer is made in suspension in a second reactor in the presence of the HMW polymer, wherein the solids concentration in the second LMW reactor, defined as the mass of polymer divided by the total mass of slurry, is at least 35 wt %, most preferably between 45 wt % and 60 wt %, and/or the ratio of solids concentration in the first reactor to that in the second reactor is maintained at less than 1.0, preferably between 0.6 and 0.8, and further wherein the volume of the second reactor is at least 10%, preferably at least 30% and more preferably at least 50% greater than the volume of the first reactor.

2010-08-19

20100210797

Polyethylene Films having Improved Barrier Properties - Blown films and processes of forming the same are described herein. The blown films generally include high density polyethylene exhibiting a molecular weight distribution of from about 1.5 to about 8.0 and a density of from 0.94 g/cc to less than 0.96 g/cc.

ANTI-IL-22RA ANTIBODIES AND BINDING PARTNERS AND METHODS OF USING IN INFLAMMATION - The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-22, IL-20, or both IL-20 and IL-22 polypeptide molecules. IL-20 and IL-22 are cytokines that are involved in inflammatory processes and human disease. IL-22RA (zcytor11) is a common receptor for IL-20 and IL-22. The present invention includes anti-IL-22RA antibodies and binding partners, as well as methods for antagonizing IL-22 or both IL-20 and IL-22 using such antibodies and binding partners.

Mimetic Drug Delivery Systems for Release with Specific Molecular Triggers - The present invention provides a molecule-imprinted reversible polymeric network composition and methods of making and using the same. In addition, the instant invention provides a composition for the delivery of an active agent. The composition includes a polymer matrix formed from at least a first and a second monomer and one or more active agents deposited within the polymer matrix. One or more recognition sites on at least one of the at least first and second monomers and an active site formed in the polymer matrix by the one or more recognition sites. The template binds to the active site by interacting with at least one of the one or more recognition sites, wherein the template causes the release of the one or more active agents.

2010-08-19

20100210836

SMALL MOLECULE INHIBITORS OF LYMPHOID TYROSINE PHOSPHATASE - The present invention relates to lymphoid tyrosine phosphatase inhibitors and autoimmunity. More specifically, the invention relates to the identification of lymphoid tyrosine phosphatase inhibitors and the analysis of the structure-activity relationship.

PLANT EXTRACTS AND USE THEREOF - An object of the present invention is to provide a plant extract which comprises o-diphenol type chlorogenic acids in a high concentration. Also, it is to provide a plant extract excellent in deodorizing property or anti-oxidation property, which does not substantially comprise ferulylquinic acids and caffeine content. The present invention provides a plant extract, which comprises chlorogenic acids comprising an o-diphenol type chlorogenic acid and does not substantially comprise ferulylquinic acid and caffeine, which is excellent in deodorizing property or anti-oxidation property.

BRACHYTHERAPY TREATMENT DEVICE - Brachytherapy devices and methods that may allow high doses of radiation to be applied to areas in need of treatment, while reducing damage to healthy tissue that may be in the vicinity. The devices and methods may utilize an expansion device and a treatment device. The expansion device may include an outer expandable assembly that is implanted into a post-surgical cavity. The treatment device may include an inner expandable assembly that is mated to the expansion device during treatment fractions, and provides a pathway for the radiation source, for example an HDR (high dose rate) afterloader source.

2010-08-19

20100210898

MAMMALIAN REPRODUCTION - The invention is designed to enhance mammalian reproduction and in particular to improve the use of existing artificial insemination catheters in combination with novel products and processes for the insemination of mammals such as pigs. The invention comprises a controlled/sustained release delivery system comprising a metabolite/carrier combination based on specific gels, polymers and/or other molecular complexes for metabolite delivery at the point of insemination in order to promote aspects of spermatozoa function.

2010-08-19

20100210900

PROPELLABLE APPARATUS AND RELATED METHODS - Propellable apparatus, assemblies and related methods including a self-enclosed member are disclosed. The self-enclosed member can include an inner surface at least partially defining an enclosed region, and an outer surface that turns outwardly to engage a cavity or lumen wall in addition to turning inward to at least partially encompass a central region defining a longitudinal path. The apparatus can include an internal drive mechanism engageable with the outer surface of the self-enclosed member to provide relative movement between the self-enclosed member and the cavity or lumen wall. A tapered member, positioned on the apparatus adjacent an end of the self-enclosed member, can provide a size transition between an outer surface portion of the self-enclosed member and an outer surface of a payload insertable within the central region. In some examples, one or more reinforcing members can be integrated within the self-enclosed member for increased durability and rotational use.

Surgical Instruments for Accessing and Stabilizing a Localized Portion of a Beating Heart - Surgical devices for stabilizing the heart are disclosed which facilitate anastomosis under beating heart conditions. Various instruments or devices may be maneuvered and secured on a retractor device to provide stabilization of the heart. An instrument mount is provided which is preferably configured to accept a surgical instrument, such as a tissue stabilizer, and to allow the instrument to be easily maneuvered to a desired position and subsequently locked into position with a simple operation of a single locking actuator. Further disclosed are stabilizer devices each having at least one surface for contacting the heart and each being adapted to be mounted to the retractor while having the ability to be positioned in the desired location against the heart.

APPARATUS AND METHOD TO CONVEY A FLUID - An apparatus includes a fluid path, a coupling, and a nozzle. The fluid path is to carry a fluid including one or more microparticles. The coupling is located in the fluid path. The nozzle is located in the fluid path to move the fluid through a stagnant region located near the coupling.

2010-08-19

20100210940

CT-Guided Focused Ultrasound for Stroke Treatment - Techniques and systems are disclosed for performing mechanical ablation of blood clots using low-intensity ultrasound. A system includes a computed tomography (CT) scanner to acquire axial scans of a target subject containing at least one intravascular blood clot, and generate volumetric CT data of the target subject based on the acquired axial scans. A data processing device is in communication with the CT scanner to process the generated volumetric CT data, and identify at least one parameter of an ultrasound beam to ablate the at least one intravascular blood clot based on the processed volumetric CT data. Also, an ultrasound ablation device is in communication with the data processing device to generate the ultrasound beam based on the identified at least one parameter, and apply the generated ultrasound beam with the identified at least one parameter to ablate the at least one intravascular blood clot.

2010-08-19

20100210948

ULTRASONOGRAPH - Provided is an ultrasonograph that can automatically optimize the sweep rate of Doppler images and M-mode images according to the heart rate of a test subject, without the need for an operator to perform a troublesome operation. The ultrasonograph is provided with a means for sending an ultrasonic beam into body tissue, a means for receiving an ultrasonic signal that has been reflected off the body tissue and a blood flow, a means for constructing a cross-sectional image of the body tissue from the received ultrasonic signal, a means for performing phase detection on an ultrasonic Doppler blood flow signal that has been reflected off the body tissue by the blood flow, a means for calculating a frequency component of the Doppler blood flow signal on which phase detection has been performed, and a means for performing a sweeping display of the calculated frequency component as Doppler images in a time series. The ultrasonograph has a heart rate measuring means for measuring the heart rate of the test subject at a predetermining timing, and the ultrasonograph also includes an optimum sweep rate calculating means for calculating an optimum sweep rate based on the heart rate obtained by the heart rate measuring means, and an optimum sweep rate setting means for setting the sweep rate of at least either of the Doppler images and M-mode images.

MULTI-STATE PERFORMANCE MONITORING SYSTEM - The present invention is directed to systems and methods for monitoring performance of a variety of activities, preferably including swimming, in a number of states. The invention may comprise an analytics application, a primary device and, optionally, one or more secondary devices or third-party devices for sensing characteristics of the performance of an activity or the environment in which it is performed. The devices are worn during the performance of the activity and contain sensors, preferably accelerometers, for sensing information pertaining to the performance of one or more activities. The information sensed may be provided to a user in the form of real-time feedback and/or made available for long-term analytics and tracking.

2010-08-19

20100210976

METHOD AND APPARATUS FOR TREATING TISSUES WITH HIFU - A method for treating a desired volume of tissue using HIFU or other energy modality to ablate a pattern of elemental treatment volumes each having a volume that is greater than that of the focal zone of the HIFU transducer but smaller than the overall volume of the desired treatment volume. In one embodiment, the pattern of elemental treatment volumes are arranged to form a shell which partially or wholly encapsulates the desired volume of tissue, which then necroses in situ due to effects other than direct HIFU damage (including some combination of ischemia, thermal conduction, inflammation, apoptosis, etc.). The necrosed tissue remains in the body and is subsequently resorbed and/or healed via normal body mechanisms.

2010-08-19

20100210986

NEGATIVE PRESSURE WOUND TREATMENT DRESSINGS AND SYSTEMS - Dressings, systems, and methods to facilitate the application of reduced pressure to an extremity, such as heel, on a patient are provided. In one instance, a dressing for treating an extremity on a patient includes a drape envelope, a transport manifold, and a pouch. The drape envelope has an outer drape member, inner drape member, and an interior portion between the outer drape member and the inner drape member. The inner drape member has fenestrations on at least an application portion. The transport manifold is disposed within the interior portion of the drape envelope. The pouch is for receiving the extremity and includes the drape envelope and a pouch-forming attachment. The dressing allows reduced pressure to be initially supplied at a remote location from the wound and avoid leaks. Other systems, methods, and apparatuses are disclosed.

2010-08-19

20100210995

SYSTEMS AND METHODS FOR TREATING SUPERFICIAL VENOUS MALFORMATIONS LIKE SPIDER VEINS - Systems and methods treat superficial venous malformations, such as spider veins. The systems and methods distribute a reactive agent, e.g., a light-reactive agent such as talaporfin sodium or verteporfin, at or near an inner wall of a vein. The systems and methods activate the reactive agent by applying energy, e.g. non-thermal light energy at a wavelength that activates the reactive agent to cause localized injury to the inner wall of the vein.

2010-08-19

20100211003

High Precision Infusion Pumps - A system architecture for closed loop control of infusion devices is described. The architecture provides means to control the flow from an infusion device as well as in some embodiments the pressure of the delivery. A variety of infusion systems are described that use the closed loop control architecture. In some embodiments the closed loop control may be adapted to current commonly used infusion means such as a gravity feed intravenous system. Other embodiments describe infusion pump system that use biasing or drive mechanisms of springs, elastomers, rotary and linear motors.