alpha-glucosidase inhibitor

α-glucosidase inhibitor

an oral agent that aids in the control of diabetes mellitus by delaying the absorption of glucose from the digestive system.

alpha-glucosidase inhibitor

any of a group of oral antihyperglycemic agents that act by competitive inhibition of alpha-glucosidase, delaying intestinal carbohydrate absorption and lessening postprandial increases in glucose levels.

alpha-glucosidase inhibitor

An oral drug that lowers blood sugars by preventing carbohydrate absorption from the gastrointestinal tract.

The alpha-glucosidase inhibitors are effective in lowering PPG because they delay carbohydrate absorption, with one meta-analysis reporting mean reductions of 42 and 49 mg/dL for acarbose and miglitol, respectively.

Thiazolidinediones, sulfonylureas, meglitinides, dipeptidyl-peptidase 4 (DPP-4) inhibitors, amylin agonists and alpha-glucosidase inhibitors are some of the different treatment classes available to type 2 diabetics - some are oral medications, whereas others must be injected.

Alpha-glucosidase inhibitors delay the digestion of oligosaccharide and disaccharide to monosaccharide by inhibiting [alpha]-glucosidases on the small intestinal brush-border, and reduce the rate of glucose absorption.

In the retail arena pharmacists who had been dispensing sulfonylureas, oral drugs that stimulate the pancreas to work harder to make insulin (and sometimes helping the body to more effectively use insulin), are also now receiving prescription orders for biguanides and, more recently, alpha-glucosidase inhibitors.

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