Socio-economic development, land use, climate change and food security are all interconnected at different scales. Decision makers in Vietnam need to be aware about the complex and uncertain relationships between global and local drivers of socio‐economic change, and take a forward look when formulating food security and climate change mitigation and adaptation policies. This study uses a novel global-­to‐local approach that combines an economic (Computable General Equilibrium or CGE) model with a spatially explicit land use model to capture change at the global, national and landscape level for the period 2010 ‐ 2030 under three scenarios. The key findings of this policy brief are presented in terms of: