Activase regulatory update

The U.K.'s NICE issued a final appraisal determination (FAD) to update its previous recommendation on the use of Actilyse alteplase to treat acute ischemic stroke. Specifically, the guidance recommends the use of Actilyse within 4.5 hours of the onset of symptoms after intracranial haemorrhage has been excluded, instead of within 3 hours of the onset of symptoms. Final guidance is expected in November.