Fig. 2

Human IgG and IgM antibody responses to rPvRON2. Reactivity indices of a IgG per person against rPvRON2 in infected individuals from Itaituba (n = 93) and infected individuals from Manaus (n = 124), b IgG response from infected individuals from Itaituba (n = 93) and non-infected individuals who had malaria in the past (n = 97), c IgM response from infected individuals (n = 56) and non-infected individuals (n = 97) from Itaituba, measured by ELISA. The differences in the total number of individuals evaluated for each protein are due to samples running out of plasma. Error bars indicate the mean with standard deviation. p values are indicated in the figure. ns not significant. Significant differences were calculated by Fisher’s test