Weitere Produktkategorien zu TCF20 ELISA Kit

Weitere ELISA Kits für TCF20 Interaktionspartner

Human Transcription Factor 20 (TCF20) Interaktionspartner

Nonsense and one frameshift variant of TCF20 were identified the patients with intellectual disability and postnatal overgrowth. Such de novo variants of TCF20 may represent a novel differential diagnosis in the overgrowth syndrome spectrum.

mutations in TCF20 are associated with Autism spectrum disorders

SPBP is a transcriptional coactivator of NRF2 regulating expression of the autophagy receptor p62.

Study has identified SPBP as a transcriptional coactivator of AR. We also show that Pax6 (zeige PAX6 ELISA Kits) inhibits SPBP-mediated enhancement of AR activity on the AR target gene probasin promoter, a repression that was partly reversed by increased expression of SPBP.

Interaction between SPBP and TopBP1 (zeige TOPBP1 ELISA Kits) was found to be mediated by the ePHD domain of SPBP and the BRCT6 domain of TopBP1 (zeige TOPBP1 ELISA Kits).

TCF20 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene binds a platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 (stromelysin 1) promoter. The protein localizes to the nucleus and displays DNA-binding and transactivation activities. It is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Alternative splicing results in two transcript variants encoding different isoforms.