E. German Secret Drug Tests Reported

The East German Communist government, needing hard currency in
the 1980s, allowed two pharmaceutical giants to test drugs on
patients, a report says.

For the drug companies, the government gave them a chance to
evade strict controls on tests that were coming into force in
western Europe, The Local.de reported. The testing was documented
in a report, "Tests und Tote" or "Tests and the Dead," aired Monday
on the German state broadcaster ARD.

Hoechst AG and Sandoz, two West German companies, paid East
Germany millions of deutschmarks for providing test subjects, the
broadcast said. The patients involved were not told they would be
getting untested medication or a placebo.

Gerhard Lehrer died in a Dresden hospital where he was being
treated for a heart attack in 1989, Der Spiegel reported. His wife
says his doctor told him he was being given an effective,
hard-to-get drug, but he became suspicious and told her before he
died to keep some of the medication.

When she had the pills tested, she learned her husband had
received a placebo. ARD investigators learned Lehrer was part of a
study for Ramipril, a drug designed to bring down blood pressure,
that was being tested by Hoechst.

Hoechst has since been merged into the French pharmaceutical
company Sanofi-Aventis, which cooperated with ARD.

The number of drug studies jumped from 20 in 1982, the report
said, to 165 in 1988. But they stopped soon after when the East
German regime collapsed and Germany was reunified.