Our research primarily centers on the development of cellular therapies. Current projects focus on the use of pluripotent stem cells for the treatment of blood disorders such as hemoglobinopathies. Our laboratory also has a long-term interest in understanding the development of the liver, including its various cellular elements such as hepatocytes, hematopoietic cells and sinusoidal endothelial cells. We also work closely with many of the investigators at BSRI using in vitro and in vivo models to study various viral and parasitic diseases with the goal of developing methods of preventing infection or new therapies.