The room was full of some of the most pioneering women in music history including Alicia Keys, Trailblazer Award winner Janelle Monaé, and Cyndi Lauper, who was honored with the Icon Award.

Patti LaBelle presented Ariana Grande with the Women of the Year Award, where she performed her hit song "Thank U, Next," sporting her signature high pony-tail, thigh-high boots and wearing a pre-fall Christian Siriano mini-dress that has yet to hit the runway.

“I want to say that I find it interesting that this has been one of the best years of my career and like the worst of my life. I’m not saying that for sympathy. I’m just saying that because I feel like a lot of people would look at someone in my position right now … and think, ‘She’s really got her shit together,’ you know? Like, ‘She’s really on it.’ Like, ‘She’s got it all," Ariana said in her candid acceptance speech. “I do, but as far as my personal life goes, I really have no idea what the f--k I’m doing,” she admitted.

20PHOTOS

Billboard Women In Music 2018

See Gallery

Billboard Women In Music 2018

NEW YORK, NEW YORK - DECEMBER 06: Singer Ariana Grande attends the Billboard Women In Music 2018 on December 06, 2018 in New York City. (Photo by Mike Coppola/Getty Images for Billboard )

NEW YORK, NY - DECEMBER 06: Singer/songwriter Alicia Keys attends the Billboard's 13th Annual Women in Music event at Pier 36 on December 6, 2018 in New York City. (Photo by Jim Spellman/WireImage)

NEW YORK, NY - DECEMBER 06: Kacey Musgraves attends the Billboard's 13th Annual Women in Music event at Pier 36 on December 6, 2018 in New York City. (Photo by Jim Spellman/WireImage)

NEW YORK, NEW YORK - DECEMBER 06: Cyndi Lauper attends Billboard's 13th Annual Women in Music Event at Pier 36 on December 06, 2018 in New York City. (Photo by Dia Dipasupil/FilmMagic)

NEW YORK, NY - DECEMBER 06: Model Ashley Graham attends the Billboard's 13th Annual Women in Music event at Pier 36 on December 6, 2018 in New York City. (Photo by Jim Spellman/WireImage)

NEW YORK, NEW YORK - DECEMBER 06: Janelle Monáe attends Billboard's 13th Annual Women in Music Event at Pier 36 on December 06, 2018 in New York City. (Photo by Dia Dipasupil/FilmMagic)

NEW YORK, NY - DECEMBER 06: Ellie Goulding attends the Billboard's 13th Annual Women in Music event at Pier 36 on December 6, 2018 in New York City. (Photo by Jim Spellman/WireImage)

NEW YORK, NY - DECEMBER 06: Singer/songwriter Dua Lipa attends the Billboard's 13th Annual Women in Music event at Pier 36 on December 6, 2018 in New York City. (Photo by Jim Spellman/WireImage)

NEW YORK, NY - DECEMBER 06: Maggie Rogers attend Billboard Women In Music 2018 on December 6, 2018 in New York City. (Photo by Mike Coppola/Getty Images for Billboard )

NEW YORK, NEW YORK - DECEMBER 06: Lauren Jauregui attends Billboard's 13th Annual Women in Music Event at Pier 36 on December 06, 2018 in New York City. (Photo by Dia Dipasupil/FilmMagic)

NEW YORK, NY - DECEMBER 06: Grace VanderWaal attends the Billboard's 13th Annual Women in Music event at Pier 36 on December 6, 2018 in New York City. (Photo by Jim Spellman/WireImage)

NEW YORK, NY - DECEMBER 06: Patti LaBelle and Ariana Grande hug onstage at Billboard Women In Music 2018 on December 6, 2018 in New York City. (Photo by Kevin Mazur/Getty Images for Billboard )

NEW YORK, NY - DECEMBER 06: Patti LaBelle and Ariana Grande hug onstage at Billboard Women In Music 2018 on December 6, 2018 in New York City. (Photo by Kevin Mazur/Getty Images for Billboard )

NEW YORK, NEW YORK - DECEMBER 06: Janelle Monáe (L) and Cyndi Lauper attend Billboard's 13th Annual Women in Music Event at Pier 36 on December 06, 2018 in New York City. (Photo by Dia Dipasupil/FilmMagic)

NEW YORK, NY - DECEMBER 06: Singer/songwriter Hayley Kiyoko attends the Billboard's 13th Annual Women in Music event at Pier 36 on December 6, 2018 in New York City. (Photo by Jim Spellman/WireImage)

NEW YORK, NY - DECEMBER 06: Musician Anderson .Paak attends the Billboard's 13th Annual Women in Music event at Pier 36 on December 6, 2018 in New York City. (Photo by Jim Spellman/WireImage)

NEW YORK, NY - DECEMBER 06: Tierra Whack attends the Billboard's 13th Annual Women in Music event at Pier 36 on December 6, 2018 in New York City. (Photo by Jim Spellman/WireImage)

NEW YORK, NY - DECEMBER 06: St. Vincent attends the Billboard's 13th Annual Women in Music event at Pier 36 on December 6, 2018 in New York City. (Photo by Jim Spellman/WireImage)

NEW YORK, NEW YORK - DECEMBER 06: Fletcher attends Billboard's 13th Annual Women in Music Event at Pier 36 on December 06, 2018 in New York City. (Photo by Dia Dipasupil/FilmMagic)

NEW YORK, NEW YORK - DECEMBER 06: (Image was captured on the LG V40 ThinQ) Victoria Monét attends Billboard's 13th Annual Women in Music Event at Pier 36 on December 06, 2018 in New York City. (Photo by Dia Dipasupil/FilmMagic)

Up Next

See Gallery

Discover More Like This

HIDE CAPTION

SHOW CAPTION

of

SEE ALL

BACK TO SLIDE

Other winners included country star Kacey Musgraves, who took home the Innovator Award and performed an acoustic performance of "Butterflies" from her newly Grammy-nominated album "Golden Hour."

From Ashley Graham to Dua Lipa and Maggie Rogers, check out all of the leading ladies in the gallery above.