NCIt Definition: Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage.

RADLEX Definition: Any of a group of malignant tumors of lymphoid tissue that differ from hodgkin disease, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant reed-sternberg cells, a characteristic of Hodgkin's disease. [MeSH]

PDQ Definition: Distinct from Hodgkin lymphoma both morphologically and biologically, Non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage. Check for active clinical trials using this agent. (NCI Thesaurus)

HPO Definition: A typer of lymphoma characterized microscopically by the absence of multinucleated Reed-Sternberg cells. [HPO:probinson]

NICHD Definition: A malignant neoplasm of the lymphatic system that is comprised of abnormal lymphocytes in the absence of Reed-Sternberg cells.

NCI-GLOSS Definition: Any of a large group of cancers of lymphocytes (white blood cells). NHLs can occur at any age and are often marked by lymph nodes that are larger than normal, fever, and weight loss. There are many different types of NHL. These types can be divided into aggressive (fast-growing) and indolent (slow-growing) types, and they can be formed from either B-cells or T-cells. B-cell NHLs include Burkitt lymphoma, chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), diffuse large B-cell lymphoma, follicular lymphoma, immunoblastic large cell lymphoma, precursor B-lymphoblastic lymphoma, and mantle cell lymphoma. T-cell NHLs include mycosis fungoides, anaplastic large cell lymphoma, and precursor T-lymphoblastic lymphoma. Lymphomas that occur after bone marrow or stem cell transplantation are usually B-cell NHLs. Prognosis and treatment depend on the stage and type of disease.

CTEP Definition: CTEP_For_FDA: 10029593/NonHodgkin's lymphoma NOS

CSP Definition: characterized by malignant lymphomas; clinically similar to Hodgkin's disease, except that the lymphomas seen in this disease are initially more widespread; most common manifestation is painless enlargement of one or more peripheral lymph nodes.

MSH Definition: Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease.

Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease.

NDFRT

MESH_DUI

D008228

NDFRT

MESH_NAME

Lymphoma, Non-Hodgkin

NDFRT

MESH_UI

M0012822

NDFRT

MIMTYPE

3

OMIM

MIMTYPEMEANING

Phenotype description, molecular basis known.

OMIM

MIMTYPEVALUE

pound

OMIM

MMR

20130709

MSH

MN

C04.557.386.480

MSH

MN

C15.604.515.569.480

MSH

MN

C20.683.515.761.480

MSH

MODIFIER_ID

900000000000451002

SNOMEDCT_US

NCI_THESAURUS_CODE

C3211

PDQ

NDFRT_KIND

DISEASE_KIND

NDFRT

Neoplastic_Status

Malignant

NCI

NICHD_Hierarchy_Term

Non-Hodgkin Lymphoma

NCI

NUI

N0000001910

NDFRT

ORDER_NO

02541

ICD10CM

ORIG_STY

Genetic condition

PDQ

ORIG_STY

Neoplasm diagnosis

PDQ

PID

1514

PDQ

PM

1997; see LYMPHOMA, NON-HODGKIN'S 1987-1997; for LYMPHOMA, SMALL CLEAVED-CELL, DIFFUSE see LYMPHOMA, SMALL CLEAVED-CELL, DIFFUSE 1991-2007; for LYMPHOMA, SMALL NONCLEAVED-CELL see LYMPHOMA, SMALL NONCLEAVED-CELL 1991-2007; for LYMPHOMA, MIXED-CELL, DIFFUSE see LYMPHOMA, MIXED-CELL, DIFFUSE 1991-2007; for LYMPHOMA, DIFFUSE see LYMPHOMA, DIFFUSE 1991-2007; for LYMPHOSARCOMA see LYMPHOMA, DIFFUSE 1991-2007, see LYMPHOMA, NON-HODGKIN'S 1987-1990, see LYMPHOSARCOMA 1963-1986; for LYMPHOMA, HIGH-GRADE see LYMPHOMA, HIGH-GRADE 1991-2007; for LYMPHOMA, INTERMEDIATE-GRADE see LYMPHOMA, INTERMEDIATE-GRADE 1991-2007; for RETICULUM-CELL SARCOMA see LYMPHOMA, LARGE B-CELL, DIFFUSE 1987-2007; for LYMPHOMA, LOW-GRADE see LYMPHOMA, LOW-GRADE 1991-2007; for LYMPHOMA, MIXED-CELL see LYMPHOMA, MIXED-CELL 1991-2007, see LYMPHOMA, MIXED 1987-1990; for SARCOMA, RETICULUM-CELL see LYMPHOMA, LARGE-CELL 1991-2007, see LYMPHOMA, HISTIOCYTIC 1987-1990, see SARCOMA, RETICULUM-CELL 1963-1986