This is the original TV series based off of the Lupin III manga. Here we are introduced to the world famous thief Lupin III, his right-hand man Jigen, his rival and sometime love interest Fujiko, and the kendo master Goemon. Also, Inspector Zenigata is there from the start to make capture Lupin.

Kenshin Himura, better known as Hitokiri Battousai, has made an oath to never kill again. To atone for his past actions he has become a wanderer who uses a reverse-blade sword to help people. He is 28 at the start of the series--which is set roughly ten years after the events of the Tsuiokuhen OVA. He saves a girl named Kaoru Kamiya and she invites him to stay at her dojo. Other characters join the cast as part of Kenshin's group as the series goes on.

Vash the Stampede is a gunman on the run with a 60 billion double dollar bounty on his head which has made it difficult for him to go anywhere without being chased and shot at. Every town he ever visits ends up being destroyed because of his pursuers, but miraculously no one ever gets killed. Meryl and Milly are two insurance agents that have been sent to find Vash the Stampede and keep him under surveillance so no more damage is caused. Meryl, who leads the pair, refuses to believe that the man they have met can possibly be the legendary gunman. This spikey haired, gangly, young man is extremely friendly, a pacifist, hates blood and suicide, absolutely loves donuts, and is a dork and a crybaby (far from a notorious outlaw). But there is more to Vash and his past than meets the eye.