Application Information: Plasminogen antibody [9E7]

AP: Use at an assay dependent dilution. ELISA: Use at an assay dependent dilution. IHC-P: Use at an assay dependent dilution. Antigen retrieval is not essential but may optimise staining. Optimal dilutions/concentrations should be determined by the end user.

Concentration

8.7
mg/ml
(Please refer to the vial label for the specific concentration)

Purification

IgG fraction

Purification Note

Purity tested by electrophoresis.

Specifications: Plasminogen antibody [9E7]

Full Name

plasminogen

Product Description

Mouse monoclonal [9E7] to Plasminogen

Background

Plasminogen is a plasma protein synthesised mostly in the liver. It consists of a single polypeptide chain and has a molecular weight of 88.5 kDa. The plasma concentration is usually in the range of 70 - 200mg/L. Plasminogen is activated by tissue-plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Plasmin consists of a heavy (A-) chain which contains 5 kringles and a light (B-) chain with the active site. Plasmin is a trypsin-like protease whose natural substrate is fibrin, with binding sites for fibrin residing on the kringles. Plasmin is essential for fibrinolysis and decreased fibrinolytic potential due to congenital defects in plasmin can lead to recurring thrombosis, thrombophlebitis and pulmonary embolism.

Synonyms

DKFZp779M0222

Host

Mouse

Clonality

Monoclonal

Clone Name

9E7

Target

Plasminogen

Isotype

IgG2a

Immunogen

Full length native protein (purified) (Human).

Antigen Species

Human

Species Reactivity

Human

Storage Conditions: Plasminogen antibody [9E7]

Storage Buffer

Preservative: 0.1% Sodium Azide; Constituents: PBS. pH 7.4

Storage Instruction

Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. We recommend to parafilm vials during storage to prevent evaporation of buffer.

Notes

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.