Caffeine Affects Fat Metabolism Like Light Weight Training

Several genes involved in fat metabolism that were methylated before the exercise lost their methyl group. Such demethylation allows genes to more easily make proteins, which suggests that more proteins involved in the breakdown of fat are being made after exercise

And in petri dishes, exposure to caffeine caused the same beneficial demethylation, probably via elevation of muscle calcium (the same mechanism that probably explains exercise-caused demethylation.

We already knew from the results that muscle-preserving (at the expense of fat) adaptations were triggered by weight training. What’s interesting is that caffeine triggers some of the same adaptations directly.