8 foods cause 90% of food allergies (click to enlarge the image). The likelihood of a negative oral food challenge is shown in relation to the respective values of skin prick test (SPT) and serum IgE (sIgE).

For oral immunotherapy (OIT), it's important whether the intervention is transient or long-lived.

There are two groups of milk and egg allergy patients based on severity. Mild patients can be exposed to heated milk or egg will helps treat food allergy. Dr Wood recommended all kids with milk or egg allergy to be considered for intro of heated egg/milk. Although Dr Wood has some cut-offs for IgEs (milk below 20, egg below 10), they will challenge kids with higher IgE (though success is low).

Can peanut proteins be engineered to block IgE binding sites that will allow for IT but be safer than normal peanut protein? Dr Wood developed a product called EMP-123 that worked best when delivered per rectum - Wood, Allergy, 2013.

Exercise is becoming a risk factor for OIT adverse effects, so no exercise within 2 hours of food OIT dosing is strongly recommended.

Dr Wood discussed the following study: Peanut SLIT in CoFAR - JACI 2013;131:119. There was some protection with slight increase by 68 weeks. But most benefit occurred within the first 44 weeks of therapy.

The Twitter summary was made possible by @DrAnneEllis and @MatthewBowdish

Several allergists did a great job posting updates from the 2014 meeting of the #ACAAI. I used the website “All My Tweets” to review the tweets. For comparison, here are the tweets from previous #ACAAI meetings (scroll down the page for the past years): http://allergynotes.blogspot.com/search/label/ACAAI

Subscribe and Connect

About Us

Disclaimer: All opinions expressed here are those of their authors and not of their employer. The information provided here is for educational purposes only and is not intended to provide medical advice. By accessing the web site, the visitors acknowledge that there is no physician-patient relationship between them and the authors.