A Professional, in-vitro forensic diagnostic test for
use in the qualitative detection of Oxycodone (synthetic
opiates) in human urine at the
sensitivity cut off level of 100 ng/ml Oxycodone established as standard by
the U.S. Department of Health and Human Services, DOT, World Health
Organization and SAMHSA. The Oxycodone test should be used separately from
the standard opiate test when Oxycodone use is suspected. The sensitivity
detection level of the Oxycodone test is considerably higher than the
standard opiate test as required to detect this specific drug of abuse.

INTENDED
USE

For a comprehensive
discussion on drug of abuse testing including typical detection time periods
see the DRUG
TESTING FAQ

The QuickScreen™ One-Step Rapid Oxycodone Test is a rapid, visual, qualitative,
competitive binding immunoassay for the detection of Oxycodone
(Percodan, Percocet, Roxicodone, Oxycontin) and it's metabolites in human urine. The test provides a fastconfirmation of the presence of Oxycodone in the subject sample at a
minimum cutoff sensitivity level of 100 ng/ml
opiates, thesensitivity level set by the
National Institute on Drug Abuse and Departments of Health and Human Services
for this specific drug of abuse. While classified as an Opiate, the chemical
structure and metabolite of Oxycodone requires a separate Opiate test with a
substantially higher sensitivity detection level than that of the standard
Opiate drug test. Consequently, a positive test result will not only confirm
Oxycodone but other opiates as well. In this regard the Oxycodone test is not
Oxycodone specific but opiate specific being able to detect Oxycodone/opiate use
at the higher sensitivity level required while the 2000 ng/ml sensitivity level
of the standard opiate test would not detect Oxycodone. Note: Where indicated, any positive test should be confirmed using quantitative
methods by a qualified testing laboratory.Note:
This assay provides only a preliminary analytical test
result. A more specific alternative chemical method such as high-pressure liquid
chromatography (HPLC) or Gas chromatography/mass spectrometry (GC/MS) must be used in
order to obtain a confirmed analytical result. For test situations requiring laboratory
confirmation by such methods please refer to the QuickScreen Pro At Home Test Kit. Clinical consideration and professional judgment should be applied to all
test results, particularly when preliminary positive results are indicated.

SUMMARY
AND EXPLANATION OF THE TEST

Oxycodone, often called a narcotic,
is an analgesic (pain reducer) which works by depressing the central nervous system.
Oxycodone is abused for its opiate-like effects. In addition to its equalpotency to morphine in analgesic effects, it is also equipotent to
morphine in relieving abstinence symptoms from chronic opiate (heroin, morphine)
use.For this reason, it is
often used to alleviate or prevent the onset of opiate withdrawal by street
users of heroin and methadone. In early studies by the Addiction Research Center
in Lexington, Kentucky in the 1960's, it was discovered that the subjective and
physiological effects of Oxycodone were greater than an equivalent dose of
morphine in opiate substance abusers. Many dosage forms are available.
Oxycodone’s behavioral effects can last up to 5 hours. The drug is most often
administered orally. The sustained-release formula has a longer duration of
action (8-12 hours). A recent study comparing controlled released products
containing Oxycodone (Oxycontin) and morphine (MS Contin) reported that
Oxycontin was twice as potent as MS Contin. As with other
opiates, Oxycodone can also depress the respiratory system
resulting in suffocation and death when overdosed. Doctors often
prescribe Oxycodone for severe or chronic pain. Oxycodone is
very addictive, both physically and psychologically. Use for only a short time
normally results in addiction.Some physical indications of opiate use include: extreme loss of appetite and weight, cramps, nausea, vomiting, excessive scratching and complaint of itching,excessive sweating, constipation, pin-point pupils and watery eyes, reduced vision, drowsiness, euphoria, trance-like states, excessive thirst, tremors, twitching, irritability,hallucinations and lethargy. For
comprehensive information on drug testing including typical half-life or drug
detection periods see the Drug Testing FAQ.

The QuickScreen™ One-Step Rapid
Oxycodone Test utilizes a unique combination of monoclonal antibodies to
selectively identify Oxycodone and it's major metabolites in urine with a high degree of
sensitivity. The test kit is a rapid, visually read screening method that does not require
special instrumentation or training.

PRINCIPLE

The QuickScreen™ One-Step Rapid
Oxycodone Test technology incorporates a chromatographic absorbent device in which the drug or drug metabolites in the sample compete with an
opiate derivative immobilized on a porous membrane for limited antibody sites. This is the preferred scientific method for qualitative assay. In the assay procedure, urine mixes with labeled antibody-dye conjugate and migrates through test device. When
Oxycodone levels are below 100 ng/ml (the detection cutoff sensitivity of the test) unbound antibody-dye conjugate binds to immobilized antigen conjugate in the Test Zone ("T"), producing a pink-rose colored band that indicates a negative result. Conversely, when
Oxycodone levels are above the detection limit, antibody-dye conjugate binds to the free drug, forming an antigen-antibody-dye complex. The complex competes with immobilized antigen conjugate in the Test Zone, preventing the development of a pink-rose colored band. Regardless of the test result, a color band is produced in the Control Zone ("C") by a non-specific sandwich dye conjugate reaction. This band serves as a built-in quality control by demonstrating antibody recognition, verifying that the reagents are chemically active, and confirming that the test was performed correctly.

Refrigerated specimens or other materials should be equilibrated to room temperature before testing.

Open the foil pouch at the notch, remove the test device, and
if required, label the device with the donor ID.

Holding the dropper vertically as shown, add
4 drops of urine into the sample well "S"
waiting 5 seconds between drops.

Observe migration, or lateral flow of the sample across the entire test
panel. Add additional sample drops if migration is not complete.

Positive results may be observed as soon as
5 minutes, depending on the concentration of
Oxycodone in the tested specimen. To confirm negative results, a complete
reaction time of 8-10 minutes is required. Do not interpret results after
15 minutes.

INTERPRETATION
OF TEST RESULTS:

Negative

Positive

Invalid

The
development of two lines, a control line and a test line, in the test
result window indicates a negative test screen for the targeted drug or
drug metabolite.

The development of only one line, the
control line, in the test result window indicates a positive test screen
for the targeted drug or drug metabolite.

The
absence of a control line in the test result window indicates an invalid
test result regardless of the presence of a test line in the test result
window.

Positive: One (1) pink-rose band appears in the control zone and no band appears in the test zone. A positive result indicates the
Oxycodone level is 100 ng/ml or higher in the test urine sample.
Negative: One
band appears in the test zone and one band appears in the control zone. A negative result indicates that the
Oxycodone level is below the detection sensitivity of 300 ng/ml. IMPORTANT: any line, no matter how faint, appearing in the test area
confirms a negative test.
Invalid: If there are no distinct color bands visible in both the test zone and
the control zone or if there is a visible band in the test zone but not in the
control zone, then the test is invalid. In this instance, re-testing of the
specimen is required.

The QuickScreen™ One-Step Rapid Oxycodone test is now available to professionals
and individuals concerned with Oxycodone abuse.
The test is one-step, fast,
self-contained, individually packaged and can be performed any time the targeted
drug use or abuse is suspected. The tests come in order units of five (5)
individual tests at a cost per single diagnosis/screen of $4.00 for the minimum
order unit. For testing situations where sample adulteration is suspect, a
Rapid Urine Adulteration test is available.

Description

Sale Unit

Cost

QuickScreen Rapid Oxycodone (OXY)
Test Cassette

Five (5) Tests

$19.90

Fifteen (15) Tests

$45.00

Thirty(30) Tests

$75.00

One Hundred(100) Tests

$190.00

Two HundredFifty
(250) Tests

$375.00

*If the
order buttons are absent or inoperable, please use the
pricing overview page to order.