Home

Education

Research

My Research focuses on novel metabolic markers of diabetes and cardiovascular risk. I investigate the role of lifestyle, nutrition, genetics, and biomarkers in the development and progression of cardiometabolic diseases.

Current work is focused on cholesterol metabolism and specifically how the presence of a small proinflammatory protein (apolipoprotein C-III) on HDL particles marks a potentially dysfunctional type of HDL that is not inversely associated with risk of cardiovascular disease. I also use candidate gene and genome-wide association studies to investigate genetic variation in cholesterol metabolism, and gene-environment interactions of importance to cardiometabolic diseases.

Investigations are conducted in the Health Professionals Follow-Up Study, the Nurses’ Health Study, the Danish EPIC cohort study (Diet, Cancer and Health), the Multi-Ethnic Study of Atherosclerosis, and the Cardiovascular Health Study.