Purpose: :
Th17 which produce IL-17 is new effecter population involvedin the progression of inflammatory disorder, such as autoimmunediseases and transplant rejection. We studied potential involvementof IL-17 in corneal allograft rejection reaction.

Results: :
Rejected group corneas were vascularized and had severe opacity,while control group corneas were clear. Although IFN-g productionwas higher in rejected group compare with control group, wecould not detect significant difference between control groupand rejected group in IL-17, TGF-b, IL-10 or IL-6 production.IL-23 was not detected in either group.

Conclusions: :
These results suggest that Th17 cells were less related to cornealallograft rejection than Th1 cells.