anti-CD83 (CD83) Antibodies

The protein encoded by CD83 is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. Additionally we are shipping CD83 Proteins (31) and CD83 Kits (15) and many more products for this protein.

Human CD83 interaction partners

this study shows differential expression and function of CD83 on human immune cells, and reveals potential new roles for this molecule as a target of therapeutic manipulation in transplantation, inflammation, and autoimmune diseases

Crystal structure of human CD83 reveals that its surface domain consists of an Ig-like domain only.CD83 exerts its immunological activity by mixed homotypic and heterotypic interactions as typically observed for proteins present in the immunological synapse.

this study shows that dendritic cells from rheumatoid arthritis patients have low expression levels of CD83

CD83(+) T cells share important features with regulatory T cells, identifying CD83 as a novel lineage marker to discriminate between different T cell populations.

CD83 Antigen Profile

Protein Summary

The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene.