Natalia was regarded by many as the performer who largely represented the latex fetish film industry during the late 1980s and early 1990s for her starring roles in many of the then leading fetish film production companies, including the now defunct Viola Bizarre and Shiny Films.

Natalia has largely retired from active fetish film production in recent years. Natalia has been quoted saying "Never say never" when asked on the issue of her returning to film production either for others or by her own production. However, it has been several years since her last publicly released film.

In the 1990s and early 2000s she was married to noted fetish film producer and director Jo Hammer, who she worked for in many of their notable productions such as the Rubber Ghost trilogy.

Today, Natalia Mühlhausen mostly works only as a professional rubber escort.