The schedules are approved by the American Academy of Pediatrics (AAP), the American Academy of Family Physicians, the Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention, and the American College of Obstetricians and Gynecologists.

New in 2014 is an AAP recommendation that pregnant adolescents receive Tdap vaccine for each pregnancy to protect against tetanus, diphtheria and pertussis, preferably during week 27 through week 36 of gestation, regardless of time since previous Td or Tdap vaccine. The 2013 recommendation called for a Tdap booster for pregnant adolescents but did not specify whether it should be administered for subsequent pregnancies.