Weight loss plus vitamin D reduce cancer-linked chronic inflammation

the ONA take:

According to a new study published online ahead of print in the journal Cancer Prevention Research, researchers at Fred Hutchinson Cancer Research Center in Seattle, Washington, have found that the addition of vitamin D supplementation to weight loss had a greater improvement in chronic inflammation compared with weight loss alone.

Chronic inflammation is known to contribute to the development and progression of some cancers, as well as other diseases.

For the study, researchers enrolled 218 healthy, overweight, postmenopausal women who had insufficient vitamin D levels. All participants participated in a diet and weight loss program and half were randomly assigned to receive vitamin D 2,000 IU daily for 1 year.

Results showed that women who lost 5 to 10% of their body weight and took vitamin D supplementation experienced the greatest reduction in chronic inflammation.

"We were quite surprised to see that vitamin D had an effect on an inflammation biomarker only among women who lost at least 5 percent of their baseline weight," Catherine Duggan, Ph.D., a principal staff scientist in the Public Health Sciences Division at Fred Hutchinson Cancer Research Center said. "That suggests vitamin D can augment the effect of weight loss on inflammation."

Addition of vitamin D supplementation to weight loss had a greater improvement in chronic inflammation.

Researchers have found that weight loss, in combination with vitamin D supplementation, has a greater effect on reducing chronic inflammation than weight loss alone. Chronic inflammation is known to contribute to the development and progression of several diseases, including some cancers.