Ayo handed La Salle a championship Season 79 of the UAAP. But the Green Archers failed to defend their crown this season, losing to the Ateneo Blue Eagles. La Salle compiled a 30-5 record under Ayo's tutelage.

But it was with the Letran Knights where Ayo perfected his 'Mayhem' system. The mayhem defense is the defensive strategy employed by Ayo to trap opponents on both ends of the floor.

Ayo ended 10 years of frustration for Letran by winning the NCAA title in 2015. The Knights stunned the San Beda Red Lions in Season 91.