Her married name became Lady Spencer.
She held the office of Lady of the Bedchamber to Queen
Anne from 1702 to 1712.
As a result of her marriage, Lady Anne Churchill was styled as
Countess of Sunderland on September 28 1702, but is not to be
confused with her mother-in-law Anne Digby, also named Anne Spencer,
Countess of Sunderland.

The title of Duke of Marlborough passed over
from her elder sister Henrietta to her son Charles.

She died at the age of 33, and was buried on April 24 1716 in Brington,
Northamptonshire.