Random and unannounced tests for human growth hormone are coming to big league clubhouses. Major League Baseball and the Players Association say the blood testing will start with the first pitch of the upcoming season.

Since 2010, baseball has tested minor league players for HGH, but tested major league players only during the offseason, spring training and for reasonable cause. Major League Baseball is the first American sports league to test for human growth hormone.

The announcement comes a day after no former player was elected to the Hall of Fame this year.