Th17

Th17 cells are present in higher numbers and expression of IL-17 is higher in psoriatic lesions compared with healthy tissue. Global gene expression studies have consistently demonstrated the upregulation of the IL-17 pathway in psoriasis.

Th1

Th1

It has been recognised for many years that the Th1 pathway is involved in psoriasis, although recent research has highlighted the significance of other pathways such as Th17.