Phys.org news tagged with:growth factorhttp://phys.org/
en-usPhys.org internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine.Simple polymer could unlock more effective bone regeneration treatmentsA new technique developed by biomedical engineers could help to unlock the full potential of a promising treatment for bone regeneration, creating better therapies for spinal injuries, bone grafts and other orthopaedic surgeries.http://phys.org/news/2016-08-simple-polymer-effective-bone-regeneration.html
Polymers Mon, 29 Aug 2016 08:00:28 ESTnews391676414Fibroblast growth factor signalling controls fin regeneration in zebrafishResearchers at Tokyo Institute of Technology found that fibroblast growth factors (Fgfs) play an important role in regeneration of damaged fins in zebrafish, offering potential clues on tissue regeneration in other species.http://phys.org/news/2016-08-fibroblast-growth-factor-fin-regeneration.html
Cell & Microbiology Thu, 04 Aug 2016 10:10:32 ESTnews389524223A surplus with consequencesWhy do healthy cells become malignant and proliferate uncontrollably? Scientists of the University of Würzburg have investigated the role of a special protein in this process and settled and old controversy.http://phys.org/news/2016-08-surplus-consequences.html
Biochemistry Thu, 04 Aug 2016 08:50:01 ESTnews389518933First signalling pathway of the digestive lineage in planarians is describedA scientific study describes for the first time the function of a signalling pathway –particularly, the pathway of epidermal growth factor receptors (EGFR) - in the differentiation of the planarian digestive lineage. EGFR pathway, evolutionarily preserved, has a fundamental role when regulating the cell differentiation and proliferation in lots of organisms (such as mammals' neural stem cells) and it is over-activated in most of human cancers.http://phys.org/news/2016-05-pathway-digestive-lineage-planarians.html
Cell & Microbiology Fri, 20 May 2016 09:20:01 ESTnews382954163Beta cells from love handlesResearchers at ETH Zurich have managed to use a synthetic genetic program to instruct stem cells taken from fatty tissue to become cells that are almost identical to natural beta cells. This brings them a major step closer to a personal repair kit for diabetes sufferers.http://phys.org/news/2016-04-beta-cells.html
Cell & Microbiology Mon, 11 Apr 2016 05:00:01 ESTnews379566183Severe water stress likely in Asia by 2050, study findsEconomic and population growth on top of climate change could lead to serious water shortages across a broad swath of Asia by the year 2050, a newly published study by MIT scientists has found.http://phys.org/news/2016-03-severe-stress-asia.html
Environment Wed, 30 Mar 2016 14:00:09 ESTnews378556254Making heads and tails of embryo developmentProteins usually responsible for the destruction of virally infected or cancerous cells in our immune system have been found to control the release from cells of a critical growth factor governing head and tail development in fruit flies (Drosophila melanogaster). This may help explain how these perforin-like proteins function in human brain development and neurodevelopmental disorders such as Autism Spectrum Disorder.http://phys.org/news/2015-10-tails-embryo.html
Cell & Microbiology Tue, 27 Oct 2015 09:28:20 ESTnews365156890Development of growth factor-free tissue adhesive porous films capable of promoting angiogenesisA group at NIMS MANA has developed tissue adhesive porous films that promote angiogenesis without using growth factors. This new technology may contribute to medical cost reduction while maintaining the quality of medical treatment. This study was published in the online version of the academic journal Biomaterials on June 9, 2015.http://phys.org/news/2015-08-growth-factor-free-tissue-adhesive-porous.html
Biochemistry Fri, 28 Aug 2015 10:30:01 ESTnews359972581How intracellular signaling regulates growth factor productionCancer cells need life-essential molecules to proliferate. These so-called growth factors are activated by ectodomain shedding of precursor proteins on the outside of the plasma membrane, mainly carried out by three human cleavage enzymes. A pharmaceutical blocking of these enzymes could hinder cancer from growing but would also inhibit other life-essential processes. Now, researchers from German Leibniz Institute for Age Research (FLI) and Harvard University, US, showed that the factor-precursor-producing cells themselves determine if and when cleavage may occur. This is decided by intracellular signaling. Interfering with defined signaling in cells producing cancer growth factors could be developed into a new way of cancer treatment.http://phys.org/news/2015-07-intracellular-growth-factor-production.html
Biochemistry Fri, 10 Jul 2015 08:20:01 ESTnews355732974Inkjet inks made of bioactive silk could yield smart bandages and other innovationsSilk inks containing enzymes, antibiotics, antibodies, nanoparticles and growth factors could turn inkjet printing into a new, more effective tool for therapeutics, regenerative medicine and biosensing, according to new research led by Tufts University biomedical engineers and published June 16 in the journal Advanced Materials online in advance of print.http://phys.org/news/2015-06-inkjet-inks-bioactive-silk-yield.html
Engineering Wed, 17 Jun 2015 07:30:02 ESTnews353742686'Open' stem cell chromosomes reveal new possibilities for diabetesStem cells hold great promise for treating a number of diseases, in part because they have the unique ability to differentiate, specializing into any one of the hundreds of cell types that comprise the human body. Harnessing this potential, though, is difficult. In some cases, it takes up to seven carefully orchestrated steps of adding certain growth factors at specific times to coax stem cells into the desired cell type. Even then, cells of the intestine, liver and pancreas are notoriously difficult to produce from stem cells. Writing in Cell Stem Cell April 2, researchers at University of California, San Diego School of Medicine have discovered why.http://phys.org/news/2015-04-stem-cell-chromosomes-reveal-possibilities.html
Cell & Microbiology Thu, 02 Apr 2015 12:00:27 ESTnews347194813Biomedical engineer developing nanomaterial for healing broken bonesA new material that triggers stem cells to begin forming bone could enable a more effective treatment for hard-to-heal bone breaks and defects, says a Texas A&M University biomedical engineer who is part of the team developing the biomaterial.http://phys.org/news/2015-03-biomedical-nanomaterial-broken-bones.html
Bio & Medicine Wed, 18 Mar 2015 07:36:33 ESTnews345882962Gold nanorods target cancer cellsUsing tiny gold nanorods, researchers at Swinburne University of Technology have demonstrated a potential breakthrough in cancer therapy.http://phys.org/news/2014-12-gold-nanorods-cancer-cells.html
Bio & Medicine Thu, 18 Dec 2014 06:21:12 ESTnews338106058Protein-engineered cages aid studies of cell functionsCarbon monoxide (CO) plays an important role in cell functions, by signalling responses that counteract inflammation, and cell growth and death. As a result, researchers have been in pursuit of molecules that release CO into cells in order to study biological responses. Now Takafumi Ueno and colleagues in Japan report in the Journal of the American Chemistry Society how they have developed a protein cage that overcomes the limitations of previously reported CO releasing molecules.http://phys.org/news/2014-11-protein-engineered-cages-aid-cell-functions.html
Materials Science Wed, 19 Nov 2014 05:50:02 ESTnews335597762Population boom, droughts contributed to collapse of ancient Assyrian EmpireThere's more to the decline of the once mighty ancient Assyrian Empire than just civil wars and political unrest. Archaeological, historical, and paleoclimatic evidence suggests that climatic factors and population growth might also have come into play. This is the opinion of Adam Schneider of the University of California-San Diego in the US, and Selim Adali of the Research Center for Anatolian Civilizations in Turkey, published in Springer's journal Climatic Change.http://phys.org/news/2014-11-population-boom-droughts-contributed-collapse.html
Earth Sciences Wed, 05 Nov 2014 09:33:24 ESTnews334402312Over-organizing repair cells set the stage for fibrosisThe excessive activity of repair cells in the early stages of tissue recovery sets the stage for fibrosis by priming the activation of an important growth factor, according to a study in The Journal of Cell Biology.http://phys.org/news/2014-10-over-organizing-cells-stage-fibrosis.html
Cell & Microbiology Mon, 20 Oct 2014 09:00:02 ESTnews333003379Biochemists target relief for crippling condition(Phys.org) —A molecule nobody thought to explore may unlock a potential therapeutic target for a debilitating connective tissue disorder, according to Western-led research.http://phys.org/news/2014-01-relief-crippling-condition.html
Biochemistry Fri, 10 Jan 2014 08:00:02 ESTnews308560471The secret of short stemsThe normal height to which plants grow is a critical trait. In the wild Arabidopsis thaliana uses the same genetic changes in the biosynthesis of the growth factor gibberellin to cut its size in half as found in semi-dwarf varieties of rice and barley that have been bred by people. When expressing the same phenotype, various plant species apparently fall back on the same genes in their genotype. There must therefore be so-called "hot spots" whose repeated mutation produces the same traits that are beneficial in some conditions.http://phys.org/news/2013-11-secret-short-stems.html
Biotechnology Tue, 12 Nov 2013 12:45:06 ESTnews303482693Super song learners: Researchers uncover mechanism for improving song learning in juvenile zebra finchesMost songbirds learn their songs from an adult model, mostly from the father. However, there are relatively large differences in the accuracy how these songs are copied. Researchers from the Max Planck Institute for Ornithology in Seewiesen now found in juvenile zebra finches a possible mechanism that is responsible for the differences in the intensity of song learning. They provided the nerve growth factor "BDNF" to the song control system in the brain. With this treatment the learning ability in juvenile males could be enhanced in such a way that they were able to copy the songs of the father as good as it had been observed in the best learners in a zebra finch nest.http://phys.org/news/2013-10-super-song-learners-uncover-mechanism.html
Plants & Animals Wed, 23 Oct 2013 09:02:33 ESTnews301737740'Vicious cycle' shields, spreads cancer cellsA "vicious cycle" produces mucus that protects uterine and pancreatic cancer cells and promotes their proliferation, according to researchers at Rice University. The researchers offer hope for a therapeutic solution.http://phys.org/news/2013-09-vicious-shields-cancer-cells.html
Biochemistry Mon, 16 Sep 2013 16:15:10 ESTnews298566899Synthetic mRNA can induce self-repair, regeneration of the infarcted heartA team of scientists at Karolinska Institutet and Harvard University has taken a major step towards treatment for heart attack, by instructing the injured heart in mice to heal by expressing a factor that triggers cardiovascular regeneration driven by native heart stem cells. The study, published in Nature Biotechnology, also shows that there was an effect on driving the formation of a small number of new cardiac muscle cells.http://phys.org/news/2013-09-synthetic-mrna-self-repair-regeneration-infarcted.html
Biotechnology Sun, 08 Sep 2013 13:00:06 ESTnews297860353Microparticles create localized control of stem cell differentiationBefore scientists and engineers can realize the dream of using stem cells to create replacements for worn out organs and battle damaged body parts, they'll have to develop ways to grow complex three-dimensional structures in large volumes and at costs that won't bankrupt health care systems.http://phys.org/news/2013-07-microparticles-localized-stem-cell-differentiation.html
Cell & Microbiology Tue, 09 Jul 2013 11:08:30 ESTnews292586896EGF growth factor accelerates cell division, study findsBiologists at Heidelberg University have discovered new approaches for the treatment of cancer. They investigated how a special signalling molecule, the epidermal growth factor (EGF), stimulates the separation of chromosomes in the cell. The researchers were able to demonstrate that EGF accelerates the division of the cell nucleus, i.e. mitosis, as well as boosts precision in chromosome segregation. "Because the regulation of the EGF pathway is radically altered in many types of cancers, the results of our research point to new approaches in cancer therapy", explains Prof. Dr. Elmar Schiebel from the Center for Molecular Biology of Heidelberg University (ZMBH). Together with scientists from the University of Leicester, the European Molecular Biology Laboratory and the German Cancer Research Center, Prof. Schiebel and his team have published their findings in the journal Developmental Cell.http://phys.org/news/2013-05-egf-growth-factor-cell-division.html
Cell & Microbiology Tue, 14 May 2013 08:51:58 ESTnews287740271Same protein that fires up cancer-promoting Erk also blocks its activationA protein which is intimately involved in cancer-promoting cell signaling also keeps a key component of the signaling pathway tied down and inactive, a team led by scientists from The University of Texas MD Anderson Cancer Center reports this week in Nature Structural Molecular Biology.http://phys.org/news/2013-04-protein-cancer-promoting-erk-blocks.html
Cell & Microbiology Fri, 19 Apr 2013 17:44:55 ESTnews285612278Symposium highlights epigenetic effects of milkIt seems the ads were right. A milk mustache is a good thing to have. Animal and dairy scientists have discovered that drinking milk at an early age can help mammals throughout their lives.http://phys.org/news/2013-04-symposium-highlights-epigenetic-effects.html
Other Fri, 05 Apr 2013 13:08:01 ESTnews284385872Jekyll and Hyde corals tell different warming story(Phys.org) —Like the rings of a tree trunk, Strontium-to-calcium ratios (Sr/Ca) in coral skeletons have been widely used to determine past ocean temperatures from yearly banded corals. However, scientists have now found that biological (growth) effects can overpower the climate information locked in the coral skeletons.http://phys.org/news/2013-03-jekyll-hyde-corals-story.html
Environment Tue, 26 Mar 2013 08:02:29 ESTnews283503741Stem cells use signal orientation to guide division, study showsCells in the body need to be acutely aware of their surroundings. A signal from one direction may cause a cell to react in a very different way than if it had come from another direction. Unfortunately for researchers, such vital directional cues are lost when cells are removed from their natural environment to grow in an artificial broth of nutrients and growth factors.http://phys.org/news/2013-03-stem-cells-division.html
Cell & Microbiology Thu, 21 Mar 2013 14:00:13 ESTnews283092106Study finds stem cells in deer antlerA team of researchers in Seoul, Korea have reported finding evidence that deer antlers - unique in that they regenerate annually - contain multipotent stem cells that could be useful for tissue regeneration in veterinary medicine.http://phys.org/news/2013-03-stem-cells-deer-antler.html
Cell & Microbiology Tue, 19 Mar 2013 10:24:55 ESTnews282907475How plants halt hair growth: A developmentally timed molecular pathway controls cell size in ArabidopsisNormal development and function in multicellular organisms relies on tight control of cell growth, yet surprisingly little is known about how such control is achieved. Although some promoters of growth have been identified, very few growth suppressors are known.http://phys.org/news/2013-03-halt-hair-growth-developmentally-molecular.html
Biotechnology Fri, 15 Mar 2013 09:19:07 ESTnews282557933New evidence highlights threat to Caribbean coral reef growthCoral reefs build their structures by both producing and accumulating calcium carbonate, and this is essential for the maintenance and continued vertical growth capacity of reefs. An international research team has discovered that the amount of new carbonate being added by Caribbean coral reefs is now significantly below rates measured over recent geological timescales, and in some habitats is as much as 70% lower.http://phys.org/news/2013-01-evidence-highlights-threat-caribbean-coral.html
Environment Tue, 29 Jan 2013 11:00:01 ESTnews278676520