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Not sure about toxins in the kelp granules, but i'd make sure to supplement with a yeast based form of selenium for at least a few weeks before hand(250mcg). As supplementing with potassium idiode has caused quite a few people some issues, and selenium has a protective affect. I wouldn't be supplementing with any more than 1gram btw and if i did supplement i'd try potassium iodide and see if you feel any hypothyroid/hyper symptoms.