Pawsitive

Pawsitive is a social application that helps all owners understand their pet’s personalities and connect with other owners about their anxieties and questions.

Piconect

Privately share audio, wherever and whenever

Piconect helps college-aged millennials who want to share music with their friends while avoiding public embarrassment and enabling greater private access to music sharing in public settings.

Smart Child Seat

Keep your child safe, every, single, ride

Our app assists parent/caregivers in ensuring that their child seat is installed correctly in their car. It also provides a modality to connect with the CPS technician community for information and product suggestions.

Croni

A tablet-based self-ordering solution where customers can place orders, earn points, and pay, increasing store’s revenues and improving customer experience. We provide both the hardware and software to our clients, and include modules for data analytics and a loyalty program to further foster revenue and empower our clients to effectively manage their business.

mHealth Engage

mHealth Engage provides mobile health researchers with a centralized repository of eligible clinical research participants who are actively seeking out opportunities to participate in research.

OncopHore Nanotechnologies

OncopHore Nanotechnologies provides a pH-sensitive nanoparticle for chemotherapeutics. Once administered, our nanoparticle remains intact until it reaches the slightly acidic microenvironment surrounding the tumor. The slight acidic pH causes the nanoparticle to dissolve and release the drug cargo, allowing for reduced toxicity and improved drug delivery.

Primary cells

We provide primary brain cell models for neurobiology research. Our cells products significantly reduce the time and cost of making cell models that provide highly relevant data on living brain cells thereby cirumventing in many cases the need to run animal studies.

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Trefo

Trefo uses teams of robots powered by AI algorithms to perform automated timber cruises that estimate volume and value of timberland. By aiming to count every tree, we vastly improve to our customers intel on timber assets. Trefo is significnatly quicker and accurate than currently available solutions.

xRad

xRad is a cloud-based medical imaging diagnostic platform that aims to empower physicians of developing nations in providing an online access to patient data and communication. Through a centralized, modular platform that integrates to specific PACS systems, xRad allows business to business communication between hospitals as well.

Spring 2018 Cohort

PCI is proud to announce the Spring 2018 Cohort for the Penn I-Corps Accelerator Program.

Cellview Sciences

Chromosense is a minimally invasive procedure to determine whether an embryo has the correct number of chromosomes. We use carbon nanopipette technology, which can pierce and manipulate single cells without inflicting damage, to inject molecular beacons into the nuclei of developing embryo cells.

Nanopore

NanoXCell Therapeutics

Applying carbon nano pipetes in a completely novel manner to transfect cells to treat Epidermolysis Bullosa (EB), a group of rare genetic skin conditions, which is characterized by extremely fragile skin and recurrent blister formation, resulting from minor mechanical friction or trauma.

PDAC diagnostics

There is currently no diagnostic for pre-symptomatic Pancreatic cancer; by the time symptoms are present the disease is generally fatal. We are developping a diagnostic based on biomarkers identified by the Zaret lab at the University of Pennsylvania.

Quantitative Radiology Solutions (QRS)

Automatic Anatomy Recognition (AAR) is a body-wide and generalizable image segmentation and analytics methodology that can be used to automatically quantify organs and diseased tissues in MRI, CT & PET-CT scans. The technology can be deployed to help physicians plan treatment and assess response for patients with cancer and neurological disorders.

Strella Biotechnology

Hundreds of millions of dollars are lost annually due to fresh apple spoilage in the packing and distribution phase. Our biosensors measure ethylene gas, which reliably and efficiently measure fruit maturation using mechanisms of the fruits themselves.

Vital Start

Developing an enhanced care management/coordination Health IT tool called SwaddleTool to support treatment babies & mothers recovering from opioid addiction.

Fall 2017 Cohort

PCI is proud to announce the Fall 2017 Cohort for the Penn I-Corps Accelerator Program.

3D Optics

Researchers and biologists who need to visualize the entire structure of a biological specimen will use our add-on imaging device along with our tissue clearing system to overcome imaging limitations and to simplify and expedite workflow unlike the existing prohibitively expensive equipment.

Basin Logix

Water Agency Managers who need to achieve sustainability and comply with new regulations will use our water exchange to reduce regulatory burden and to streamline the transfer of water unlike legacy water transfer operations.

BCC

Lung transplant teams who need to transplant lungs will use our Biomimetic Chest Cavity to limit damage to lungs ex-vivo and therefore increase the pool of available organs unlike traditional cold buffer storage and EVLP.

Bone on a Chip

Research Investigators who need to test the efficacy of their bone-related drugs will use our bone-on-a-chip to reduce time, money, and effort in large animal models/clinical trials and to produce translatable data unlike small animal models.

DentaCheck

General dentists who need assistance in diagnosing x-rays will use our cloud-based, HIPAA-compliant dental software to minimize the x-ray diagnosis error rate and to augment their expertise, unlike the slow process of getting a second dental treatment opinion.

Eager

Software platform to assist teachers and school administrators to support struggling students by assessing student risk dynamically, communicating student progress to stakeholders, and implementing school-wide behavioral rewards system.

Jetlag Goggle

Jet lag and social jet lag suffers, who need to improve their sleep, will use our Jet Lag Goggle providing dynamic lights to realign the circadian and to improve their sleep, unlike sleeping pills.

Naanoscope

Mental healthcare providers who need to diagnose, monitor and document treatment progress for patients with depression will use Naanoscope, which is a package that monitors behavioral and physiological measures to improve prognosis and improves documentation by reducing subjectivity.

NeoNur

Neonur is a neurocognitive assessment tool, utilizing the late gestational developmental pattern of coordination of suck swallow and breath, to aid in the monitoring of the readiness to orally feed, and neural development. Neonur provides appropriate oral feeding guidance to NICU staff and feeding specialists for both infant and mother resulting in improved care preventing readmissions, decreased anxiety, and the potential for earlier discharge from the hospital, and the researcher a tool to better understand neurocognitive delays.

NurseMatch

Charge nurses who develop nurse-patient assignments will use our software to reduce the time, stress, and complexity of current methods, and make assignments more data-driven and efficiently unlike current manual approaches.

ReNeruon

Neurologists and Neurosurgeons specializing in Parkinson’s disease who need to treat their patients will use our bio-engineered neural pathway to slow the progression of the disease and to restore motor function unlike current available treatments such as DBS and other medical interventions.

Zmartar

Health departments who need real-time water quality reports will use our digital early warning system to eliminate exposure to water-borne pathogens and to increase rapid and accurate diagnoses unlike day-long lab methods.

Instructors

Spring 2017 Cohort

PCI is proud to announce the Spring 2017 Cohort for the Penn I-Corps Accelerator Program.

ABSCOPAL Effect

The primary objective of this application is to perform proof-of-concept study for a novel, molecular-targeted radiotherapy for patients with metastatic melanoma. The proposed study will perform per-clinical characterization of a novel radio-iodinated form of L-DOPA. Based on perviously conducted preliminary studies, we expected to selectively delivery radio-iodinated L-DOPA directly to the tumor, thus providing improved anti-tumor activity in primary and metastatic melanoma lesions.

Antanna

The Respi-Bed is an innovation that updates and consolidates existing technology already available with the ability to be used on every hospital bed. The design allows us to incorporate multiple monitoring and support systems onto a hospital bed, simply using the space currently taken up by the headboard

Blaise

low cost, modular, scalable, compact, and light weight and intravenous infusion device with a full color, intuitive and easy to program wireless touch interface with an integrated camera scanner to scan bar code and QR codes with an additional and monitoring capabilities to support auto programming.

Blood Substitute

Our technology is an artificial protein that can bind and release oxygen under physiological conditions. It holds promise as a blood substitute for trauma patients when blood is not available for transfusion. Since the protein is simple, stable and well understood, its properties can be modified to increase efficacy and reduce toxicity. This type of redesign is often not possible in natural proteins. Additionally, our protein can be quickly and cheaply produced in quantity from bacteria.

Bone Boys

Our product is the “bone-on-a-chip,” which is a small, patients-specific device that emulates bone microarchitecture and function in vitro. It will contain a porous bone structure with real bone that is generated from high-resolution MRI images (MRI to 3D rendering to 3D printing). Thus, the device will allow the user to perform pre-clinical trials of drugs, providing a non-invasive alternative to methods such as animal testing.

Ostiio

Current distractor systems used for expanding bones in the face/skull have an external component that protrudes through the skin to allow for activation of the device with a screwdriver; this is both a source of infection and social isolation. Our technology eliminates this problematic component, with activation instead being achieved wirelessly, through a magnetic mechanism. Importantly, this technology allows for a novel device that is fully buried under tissue.

Doctigo

Doctigo is a mobile recruitment app for moonlighting doctors, improving the way hospitals fill vacant shifts. Doctors build a profile, browse shifts and pick up extra work with less hassle. Doctigo unlocks maximal utility from the internal hospital workforce and reduces the need for expensive temporary staff via recruitment agencies. Doctigo is a finalist in AppItUP 2017, with a prototype app nearing completion.

Floureer

For micro-entrerpreneurs and super individuals who want to make an impact by doing what they love, Floureer is a user-centered professional social platform that empowers users with democratized coaching and emotion-triggered profiles that attract resources and opportunities. Unlike other job marketplaces, Floureer empowers users to create a flourishing career rather than just “finding jobs or people.” In addition, Floureer provides all-free resources for laid-off population as its social impact.

Kidsmile

Parents Input children’s voice using speech recognition system and Google API, and checklist of children’s behaviors. Then, the algorithms behind the app refers online pre-installed database children’s development research and assessment (for example, Child Behavior Checklist critique, Dynamic Indicator of Basic Early Literacy and Kids Integrated Data System by GSE). We also aim to collaborate with Dr. Michelle Johnson PM&R who invented Smart Toy Gym to expand the data collection and accuracy.

NanoSink Technologies

NanoSink utilizes metal sheets (developed by the Singh Center) with macroscopic surface area and nanoscale thickness as a replacement for common heatsink components, such as vertical fins. Using photolithography and atomic layer deposition (ALD), we can create a corrugated pattern which gives the plates structural integrity where otherwise they would be as flimsy as cellophane. Our models show order of magnitude improvement in heat removal while being smaller and requiring less powerful fans.

VisiPlate

VisiPlate is a nanoscale drainage implant for open angle glaucoma patients. It consists of an ultrathin alumina plate attached to a small silicone drainage tube and is surgically implanted in the eye. The ultrathin (25-100 nm) plates have a honeycomb corrugation that provides rigidity, allowing for easy manipulation by hand and exceptional strength. By draining fluid from the eye to a space above the plate, VisiPlate lowers intraocular pressure and prevents blindness. Y-Prize 2017 winner (https://yprize.upenn.edu)

Fall 2016 Cohort

PCI is proud to announce the Fall 2016 Cohort for the Penn I-Corps Accelerator Program.

Amavii

Air-gun based technology to research traumatic brain injury (TBI) at the cellular level

The device is composed of a patented air-gun based technology that can vary pressure frequencies to study a wide range of cellular injury and response, and an imaging component that allows for real-time observation. Initially intended as a research tool to study cellular injury due to traumatic brain injury (TBI).

Cellecture, LLC

Fully automated and closed system for T-cells for adoptive cell therapy.

DURCHBLICK

Kayak for online groceries, a price comparison tool

DURCHBLICK is a price comparison tool for online groceries, that allows users to save up to 30% on every purchase by comparing the price of their individual, full basket across all online grocery retailers. Through our ‘shopping list tool’ we further enable users to do their weekly shopping in less than 15 minutes.

ed.ONWARD

Connecting schools with where they want to go

An integrated education platform that connects organizations with wellness solutions and passionate practitioners.

EyeTool

Modular low cost multifunctional tool for cataract surgery.

Flexible Meniscal Biter

Safe and effective meniscus tear treatment

Current instruments and techniques often cannot treat meniscus tears optimally. We are developing methods and devices that will make meniscus tear treatment safer and more effective. These innovations are protectable intellectual property. Ultimately, we plan to manufacturer or license this technology.

inTouch

Stay connected to the people that matter most.

inTouch is a mobile application that keeps non-sales professionals connected to the people that matter most. It is a works by streamlining their personal and professional contacts across different social mediums (ie. texts, emails, FB, Linkedin), intelligently reminding them to keep in touch, and allowing them to reach out with just a few clicks (using pre-made drafts and calendar integration).

Mechano-Therapeutics

Deliver drugs when needed using mechanical signals

A mechanically-activated drug delivery platform to deliver therapeutics in response to physical activity to augment repair of orthopaedic tissues using novel microcapsule technology.

NeuroFlow

Biometric data to improve the assessment and treatment of mental health illnesses

NeuroFlow’s software platform quantifies stress using electroencephalogram (EEG) data, allowing physicians to measure a patient’s mental health over time and in response to various treatments. This software is used in combination with plug-and-play wireless EEG headsets that allow for minimal interruption of doctors’ and therapists’ current workflow and time constraints.

Pal.ly

Smart robotic pet companion to reduce social isolation among the elderly population

Reproducibility as a Service

We help increase trust in data science by autiomatically reproducing and logging analyses.

Ninety percent of scientists acknowledge a reproducibility crisis, they cannot replicate previously published works. Computational research and Data Science in particular should be reproducible because these analyses can be scripted. RaaS is a cloud based assistant that follows data scientists, replicating and logging everything they do. This ensures others can trust and replicate computational workflows.

revoLOOtion

revoLOOtion aims to solve the sanitation crisis starting with ⅔ of the world who doesn’t have access to private toilets. We provide dignified, delightful-to-use, odorless, rapid-drying composting toilets to urban families in high density informal settlements who have had to rely on unhygienic shared toilets or no toilets at all (read: open defecation).

Sanguis

At-home blood count testing for chemotherapy patients

Sanguis is a blood cell count monitoring device that patients can use at home to track their health.

Summer 2016 Cohort

PCI is proud to announce the 2016 Cohort for the Penn I-Corps Accelerator Program.

Breaux Capital

The first fintech startup empowering Black male millennial to pool and invest their money while building their community – together.

Sitting at the intersection of fintech, financial education, and a lifestyle membership club; Breaux Capital is the first financial services startup for Black Male Millennials. Inspired by organizations that empower women to build wealth & culture, Breaux Capital empowers Black millennials, with a focus on Black males, to leverage the power of pooling capital resources for wealth creation. We provide a platform for members to: gain investment and entrepreneurial knowledge, equitably invest their money, network, and serve their community as a cohesive group via our products BreauxEDU and BreauxBOX as well as our membership club the Breaux100.

MeMix

Easing mealtime disruptions, the must-have mealtime app

MeMix is a mealtime solution based on research and accepted behavior change strategies and tailored to the unique needs of children with Autism Spectrum Disorder. MeMix is an app that promotes nutrition-based education, positive behavioral reinforcement and social support. Incorporating gamification, MeMix helps children with Autism Spectrum Disorder adopt healthy eating behaviors through an interactive platform engaging both parents and children. MeMix provides the framework to ease mealtime frustrations for parents and promotes healthy eating in children

Rehab CARES

Novel robotic technology delivers affordable, accessible, and effective rehabilitation to all regardless of where they live in the USA and the world

To deliver affordable, accessible, and effective (AAE) rehabilitation to all, regardless of where they live in the world. We engage in a socially responsible rehabilitation by focusing on the design and development of this holistic device that can be sent anywhere in a crate/box to support rehabilitation service delivery in low resource settings in the USA and worldwide, as well as enable access to rehabilitation of underserved persons with activity limitations and impairment due to aging, disease or trauma. While AAE forms the core of our innovation, Rehab-in-a-BOX reinforces community-based rehabilitation, social, engaging and fun therapy – all of which will augment the rehabilitation process tremendously.

TEAM:

Michelle Johnson

Roshan Rai

Suneet Sharma

RightAir

Developing a vest that severe COPD patients wear to offload their work of breathing and alleviate their shortness of breath.

Severe COPD (chronic obstructive pulmonary disease), popularly called emphysema, is a smoking-related lung disease that causes 2 million Americans to suffer years of intolerable shortness of breath. RightAir’s AIR-AD, is a respiratory assist device that fits like a vest over the chest and offloads the work of breathing. With each breath in, the AIR-AD generates a vacuum that helps lift the chest and abdomen, drawing air in. With each breath out, the AIR-AD increases pressure over the chest and helps the patient breath out faster. By assisting the work of breathing, patients no longer feel short of breath and can once again engage in normal daily activities.

TEAM:

Kartik Bhamidipati
Jake Brenner
Perry Dubin
Zaw Min Oo

Root

Root, is an outlet attachment that controls, monitors, and optimizes electricity usage. It uses a data driven approach with regards to the users Bluetooth and Wi-Fi signals in order to make decisions about energy waste. For example, if a user leaves home and leaves appliances on, he gets notifications asking if they should be turned off.

TEAM:

Ahmad Attia

Lawrence Choi

Vincent Po

Michael Raevsky

Stratton Spirou

Jeff Wang

Don Yu

Spring 2016 Cohort

PCI is proud to announce the 2016 Cohort for the Penn I-Corps Accelerator Program.

Animotion

Automated Anatomy Recognition (AAR):

A solution to Quantitative Radiology by localizing and delineating of all major organs in multiple body regions using MRI, CT and PET/CT images for applications in radiation therapy planning, medical oncology and surgical planning