Hahn DL Fam Pract 1995; 41:345-351*** The first report of a dramatic effect of antimicrobial treatment of adult asthma, using patients as their own controls. The effect appeared to be “bimodel”, i.e., it was either dramatic or did not occur.

Follow up clinical experience suggests that clinical relapses in some patients tend to occur after about two years, but they often respond to re-treatment.