Ian Jones summarises a number of studies that consider the benefits and harms of antidepressants during pregnancy, including a recent cohort study that found that exposure to antidepressants in the womb is associated with a modest increased risk of speech and language disorders.

Only 6 studies were available for this review of the adverse effect of lingual and buccal orthodontic treatment. The available data suggests that lingual orthodontic techniques may induce higher levels of pain, speech difficulties, and oral hygiene problems but thes findings should be views with caution because of the limited quality of the evidence.