Now, after having a grapefruit-sized tumor removed and undergoing four rounds of radiation and chemotherapy, Quivers returned to the studio this week and announced she is cancer-free.

"It's pretty amazing. I was brushing my teeth this morning and thinking about going back on the air for the first time after surgery and how incredibly difficult that was. And today not feeling anything at all," Quivers said Wednesday on the show, according to The Hollywood Reporter. "It was just a normal day. You can get up and brush your teeth, throw in your clothes and run out the door."

Stern, who has worked alongside Quivers since 1981, sincerely expressed how happy he was to have his sidekick back.

"I've been praying for this day and I'm really happy that you are here and it makes me very, very happy. Honestly, I did not think this day would come. I was very, very depressed over your illness. I wasn’t sure what the outcome was gonna be," Stern said on-the-air. "There were times I really did think I was going to lose you permanently… I'll tell you what, this is a pretty remarkable day that you are here triumphant and cured… I could never be without you again."

Stern talked about how difficult it is for him to do the show without Quivers in May 2012, when she first announced her surgery.

"Doing a show without Robin is like cutting off my left arm," he said on the show. "Or my right arm. Or maybe both. She was my backbone, you understand. Where I would lose courage, Robin always had the courage. She always is the brave one. Always the brave one with me. I could go to her, and I could always rely on her."