Antioxidants are the crusaders against the free radicals and the oxidation processes that damage our skin and our health. Some antioxidants are produced naturally by our bodies. Also, we now know that many substances, including vitamins, minerals and certain foods and topical ingredients contain powerful antioxidants which can supplement what our bodies produce. This is important to know because as we age, our antioxidant levels decrease, so supplementation is essential.

OXIS International, Inc. develops technologies and products to research, diagnose, treat and prevent diseases of oxidative stress associated with damage from free radical and reactive oxygen species and the related increased inflammation that accompanies oxidative stress. OXIS presently holds the rights to four therapeutic classes of compounds in the treatment of oxidative stress, and has focused commercialization programs in clinical cardiovascular markers, including MPO (myeloperoxidase) and GPx (glutathione peroxidase), as well as the super potent antioxidant, Ergothioneine, that is planned to be introduced as an over-the-counter nutraceutical supplement.

OXIS prepares to bring a unique compound called Ergothioneine, one of the more powerful antioxidants available, into the highly lucrative nutraceuticals market. With its proprietary method for commercially producing Ergothioneine, OXIS plans to become the primary worldwide source for the molecule. OXIS has tested and commercialized Ergothioneine as a nutraceutical dietary supplement (Ergo-Pur™ and Ergo-plex™). Additionally, several companies, including two major international cosmetics firms, use Ergothioneine as an anti-aging agent in skin-care products.

OXIS's customers include leading pharmaceutical companies such as Pfizer, Glaxo SmithKline and Genzyme and universities such as Baylor College of Medicine, University of Minnesota, Virginia School of Technology, distributors and government laboratories.

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