ABSTRACT BOOK - Index Risk factors for suboptimal efficacy of 3-factor prothrombin complex concentrates in emergency reversal of anticoagulation with vitamin k antagonists in patients with major bleeding

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F. Dentali, D. Imberti, E. Tamborini Permunian, E. Croci, W. Ageno

Role of ABO blood group and of thrombophilic abnormalities on the presence of residual vein obstruction after deep-vein thrombosis of the lower limbs

Cerebral venous thrombosis and myeloproliferative neoplasms: results from an international database of 706 patients with cerebral vein thrombosis and from 2,267 patients with myeloproliferative neoplasms

The iceberg of multidrug-resistant bacterial infections in Internal Medicine has not completely emerged: it’s time for reappraisal. Results of a case-control study in a High Care Internal Medicine Unit

ABSTRACT BOOK - Index Inverting clichés on the progressive care model in Hospital and on the role of “the doctor in charge of care” (medical tutor): results from an inter-disciplinary comparison in Tuscany

Diagnosis and timing of a new hospitalization in the first 30 days after discharge in patients with hyperglycemia and correlation with the management of patients upon discharge from the hospital: our experience

Introduction: The diagnosis of food hypersensitivity (FH) in adult patients with gastrointestinal symptoms, beyond the immediate IgE-mediated clinical manifestations, is very often difficult. The aims of our study were to: i) evaluate the frequency of FH in patients with irritable bowel syndrome (IBS)-like clinical presentation; and ii) compare the diagnostic accuracy of two different methods of in vitro basophil activation test (BAT). Materials and Methods: Three hundred and five patients, (235 females, age range 18-66 years) were included and underwent a diagnostic elimination diet and successive double-blind placebo-controlled (DBPC) challenges. Two different methods of in vitro BAT (CD63 expression after in vitro wheat or cow’s milk protein stimulation) were evaluated: one was performed on separated leukocytes, and the other on whole blood. Results: Ninety patients of the 305 studied (29.5%) were positive to the challenges and were diagnosed as suffering from FH. BAT on separate leukocytes showed a sensitivity of 86% and a specificity of 91% in FH diagnosis. BAT on whole blood showed a sensitivity of 15%-20% and a specificity of 73% in FH diagnosis (p