Red presents the Task Force with a Blacklist case searching for a plastic surgeon who creates new identities for wanted criminals. Liz and her sister, Jennifer, secretly investigate the events that took place the night the real Raymond Reddington died.

While Liz and the Task Force track a notorious underground biohacker, Red initiates a strategy to extricate himself from a problematic position. Meanwhile, Cooper's integrity is tested with a difficult choice.

Red acclimates to his new surroundings in federal prison, where he is challenged by an old rival. Samar goes undercover to stop a black market organization that fronts cash to criminals. Meanwhile, Liz and Jennifer continue their investigation into Red's past.

When Red is sent to a federal medical institution following his request to the court for a psychiatric evaluation, Liz and Jennifer use his time away to search for a Blacklister they believe may have valuable information about Red's past.

When Liz and Jennifer search for a woman who may know a secret about Red's past, they find themselves in the cross-hairs of a ruthless smuggler, forcing Liz to ask an unexpected source for help. Meanwhile, Red mediates between two rival gangs in prison.

Cooper puts his reputation on the line to appeal to the White House on Red's behalf, as Liz and the Task Force resume their search for The Corsican, a Blacklister with ties to an international conspiracy. Meanwhile, Samar's abilities in the field are tested.

The Task Force searches for a woman who specializes in hostile takeovers of criminal organizations, and may have intelligence connected to an international conspiracy involving presidential advisor Anna McMahon. Meanwhile, Aram enacts a daring plan to gain leverage over Red.

Liz and Ressler investigate a Blacklister who offers to erase gambling debts - at a deceptively high price. Meanwhile, Dembe grows concerned as Red tests the loyalties of their business associates in search of the individual who turned him in to the police.

Red and the Task Force spring into action to stop an anti-capitalist terrorist group from kidnapping and torturing the children of the one percent. Meanwhile, Ressler goes behind Liz's back to find out what happened to her mother, former KGB operative Katarina Rostova.

When a frozen corpse is discovered in the woods, the Task Force is drawn into the investigation of an old case that has gained notoriety due to a popular true crime podcast. Meanwhile, Red visits Dom Wilkinson for help making a difficult decision, and Ressler makes a discovery about Katarina Rostova's past.

Alone in a foreign country after a mission goes catastrophically wrong, Katarina Rostova goes on the run to avoid the forces trying to hunt her down. Isolated and out of options, she seeks out the only person she trusts, a man who has vowed to always protect her.

When multiple children are abducted under similar circumstances, the Task Force rushes to find the kidnapper. Meanwhile, Red goes on the hunt for a man who can find anything, while Liz considers a big change.