A man runs for cover after alleged shelling Tuesday by Syrian government forces on the Bustan al-Qasr neighbourhood of northern Syrian city of Aleppo. (Karam al-Masri / AFP via Getty Images)

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BEIRUT — Syrian activists say that two days of heavy clashes between Kurdish fighters and al-Qaida-linked rebels in the northeast have killed at least 41 on both sides.

The Britain-based Syrian Observatory for Human Rights says the clashes in Hassakeh province pitted Kurdish militias against rebels from two al-Qaida-linked factions — Jabhat al-Nusra and the Islamic State in Iraq and the Levant.

Such rebel infighting has become common in recent months in the northeast, which has a large Kurdish population.

Observatory’s director Rami Abdul-Rahman said Wednesday that 29 of the dead are from the two extremist groups, while the remaining 12 are Kurdish fighters.

Blast in southern Syria kills 21

An explosion struck a vehicle packed with passengers traveling in southern Syria overnight, killing at least 21 people, including four children, activists said Wednesday.

The deaths came as Muslims observe the holiday of Eid al-Adha, or the Feast of Sacrifice, and underscored just how relentless the violence in Syria’s civil war is. Since its outbreak in March 2011, the conflict has claimed the lives of more than 100,000 people, and forced some 7 million to flee their homes.

The blast hit the vehicle around midnight Tuesday as it was driving near Tel al-Juma in Daraa province, the Britain-based Syrian Observatory for Human Rights said. Six women were also among the dead, it added. It was unclear what kind of vehicle was involved.

It was not immediately clear what caused the explosion, nor why a group of women and children were traveling in dangerous and disputed territory in the middle of the night.

The Observatory said local activists accuse government troops, who are stationed at an army outpost in the area besieged by rebels, of planting explosives by the roadside. However, roadside bombs are frequently used by rebels to target highways traveled by regime forces.

The Observatory also reported government shelling in Daraa province and the rebel-held suburbs of Damascus, as well as air raids in the central province of Hama and Idlib province in the north. There was no immediate word on casualties.

Syria’s revolt began with largely peaceful protests against President Bashar Assad but later descended into civil war. Now in its third year, the conflict has carved the country up into rebel- and regime-controlled areas, with front-lines crisscrossing the country.