Hmm pressed send to soon!
Mum told me the other day her friends daughter had multiple miscarriages- she is known as a female bleeder (mum couldn't tell me much) but apparently when she gets pregnant her blood thickens too much causing miscarriage, so for her she was put on asprin once pregnant. Mum told me this cause apparently a grandmother and some great aunts in our family were the same :s

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HUGE APOLOGIES FOR THE LONG POST…
I thought I would give a history of our attempts at TTC and why i think i need to stop stalking this thread and join.

I was diagnosed with PCO when I was 16 and was told by my gyno at the time to come back when I wanted to get pregnant, fast forward to 29 (2003) when I was married and then we tried to save a bit- didn’t work, and began trying to conceive in 2005.

We tried for 12 + months when I was then referred to an IVF specialist.
We did our first down reg cycle in 2006 where we got 29 eggs, we were over the moon and thought we have lots of chances here- we were very green and naive then. Only 3 survived after fertilization etc. (eggs immature)

I became so sick with the cycle,I had a constant migraine for a month, a fresh embie was transferred and I was then put in hospital doped up on pethidine fir two wks and suffered my first BFN.

We had a break between March 2006 and Dec2009, during that time I developed severe depression

2009 I found out I was gluten intolerant, and guess what? Gluten can cause infertility as well as depression and in my case was the main culprit for my debilitating migraines. This made a huge difference to OUR lives. DH had his wife back. Weight that had crept on from depression was starting to drop off with eliminating gluten.

Dec 2009 a FET BFN we then had another break and tried clomid, FS thought it was a waste of time but I wanted to lose more weight as well as try and get some money behind us, living on one income for a while didn’t help the ivf finances.

I don’t think we ever thought it would take this long ( I suppose do any of us?) as both my SIL’s have had 5 kids between them with ivf and all bar one were all first tries..GRRR!...no pressure at all!!

April 2011 we sit down with FS and discuss our options, FS seriously saying we need to give this a ' real go' not coming and going as we are getting older.

May 2011 I did an Antagonist/ICSI cycle (this was heaven compared to my last cycle no side effects!! We found during this cycle that DH now has a low sperm count), 16 eggs and we are fortunate with 5 blastocysts. Transfer a fresh embie, even though I have mild OHSS. FS assures me it will be ok. I get a BFP on my 37th birthday- woo hoo this has to be a sign doesn’t it?? HCG 190… 2 weeks later on my way to babysitting my brothers kids (they are my world) I have brown discharge. I panic and ring my mum (DH at work) and then ring my FS. He says not to stress due to the colour but to go see my GP tomorrow if I’m concerned (it was on a weekend). GP books me in for a scan and BT's Nothing can be seen during the ultrasound and need an internal, sonographer finds the sac but no heart beat and the embie is measuring 1.5 wks behind. Then your mind goes into overdrive, maybe I implanted late, the sonographers not perfect they may have missed the heartbeat, it could be too early etc. We ring FS and tell him and he says to come and see him on the Monday for another scan. We are now 7 wks, no heart beat but there was growth- I grasp on to that, FS tells me that I am more than likely going to M/c. No I’m not- I’m not giving up on my child! FS says to have another scan in a week locally and then to come see the FS who is covering for him while he is at a conference. We scan again at 8 weeks and there was definitely no growth or hb, I still had had no further bleeding. It was then recommended I have a D&C as my body was not responding accordingly. I have never been in so much pain, as I was following this procedure. It was like I was going through labor (not that I have experienced it, just what I imagine), with every clot I expelled my abdomen contracted. I was about to call the ambulance when I rang the relieving FS who saw me at her rooms at 11pm that night. She examined me and thought I must have an infection. I was placed on 3 diff types of antibiotics and pain killers.-MMC8+3 wks. I never POAS with this pregnancy.

Aug 2011 we do another FET blastocyst, nothing different was tried, I start to notice the very light brown discharge/headaches and start to wonder if this is happening again. 1st BT HCG 93 I m/c at 6 wks naturally.

Sept 2011 meets with FS and discusses doing further tests, He agrees even though I have only had 2 m/c, it’s too early to be labeled with recurrent miscarriages. He tests for blood clotting disorders, lupus, Karyotype (both of us normal), hep and all your other basic first tests. All come back clear/ normal.

Oct 2011 FS agrees to put in two blasties, I am given the lecture. I nod at all the right times and just state we are aware of the risks. I am put on baby aspirin (as it can’t hurt); Was taking COQ 10, Vit E as well as my pregnancy vitamins. 5 days later I know I’m pregnant again, I didn’t do a test, I can read my body very well and was noticing the subtle changes. 5dp5dt I get a faint BFP on an hpt. 7dp5dt I develop a sorethroat/ shocking headaches it continues to get worse where I have a temp of 40,placed on antibiotics, 2 days later I start to bleed 9dp5dt HCG 1- chemical. I think t cooked the embies.

Dec 2011 we discuss with FS about doing another Antag/Icsi cycle and freezing all the embryos due to mild OHSS and that I want my body to be at its best when transferring an embryo and not already traumatized. He tried to talk us out of our decision due to the money that we would lose, but we were firm. I also spoke to him about NK cells, he stated he still believed there is not enough evidence to support their impact on pregnancy but would be willing to treat me as though I had them with prednisone. ( only a short script as he is concerned with side effects) We get 16 eggs, only 8 fertilize and we are told by the embryologist that my eggs on day 2 are no good and to think about freezing some at Day 3 to have some in the bank. That was the worst 24 hrs of ourvlives, we questioned if we should have done the cycle, did we just waste 16 of my eggs and our money etc...Get a call the next day and told that 3 of the eggs were excellent and they advised to freeze them today and let the others grow to weed out the weaker ones. None others survived. I put a complaint in about the embryologist too.

Jan 2012 I quit my job (social worker) too stressful, thought this could be contributing to the recurrent m/c

Feb 2012 we go on a 10 day cruise sth pacific to be relaxed for the next FET and just needed a holiday, it was great didn’t think about IVF once. Out of sight out of mind.

April 2012 we transfer 2 Day 3s, i start on steroids same day as FET for 5 consecutive days, again I knew I was pregnant by 3dp3dt, this was confirmed with a faint BFP at 7dp3dt. My grandfather passed away during these two weeks, and I kept saying to myself when one life is taken another is created. We were so nervous about doing this cycle too, the embryologists words kept ringing in our heads. It was confirmed with an early HCG 112 11dp3dt, HCG 351 13dp3dt and then HCG 1763 16dp3dt- it was doubling every 1.3 days- absolutely perfect. EDD will be christmas day - my grandmothers birthday, she so wanted to see me with a baby before she passed (Another sign??) No bleeding had all the symptoms everything was going along smoothly and exactly 7 weeks we see the hb and what a beautiful sight that was- i burst into tears. Did we finally make it? Was it safe to start breathing?
That weekend I start to get pain in my buttocks, down my leg and through my hip–it hurt to walk too and the headaches were getting bad. I was constantly waking with one. I didn’t think anything of it. Then 9 days later I see that dreaded brown discharge and know instinctively what that’s meant in the past. (I had just put my ticker on bubhub too and hoped I wasn’t jinxing myself, as well as my BIL and SIL bringing their cot and accessories over for us to use- double jinx). I was at my in laws (all DH’s family was there- Dh was at work) and I ran out of there, firstly telling MIL what was happening. I get home call my mum who comes straight over. I call the Royal Women’s Hospital first who tell me they cannot do anything and then I call the Epworth who tell me to come straight away. BT’s were done and I was told to come back for an ultrasound in the morning. I dread going to ultrasounds now I think I’m developing a phobia,it’s always bad news…of course there was no HB and bub had stopped growing 5 days after the 7 wks scan. Why was my question? We were sitting at the hospital, in a room for privacy and I felt the world was spinning and I was standing still. Everything was textbook, HCG was perfect, it was in the right position, I stopped work, and I was virtually on bedrest. It just didn't make sense...I had a D&C at 9+1 wks and a biopsy was taken- the results revealed an abnormality trisomy 13 and duplication of 5&7. Nature being cruel, but it was positive that there seems to be no reason I can't carry a child.

We still have two frosties, FS wants to do same regime as last transfer, prednisone for first 5 days of FET and transfer both embies. Feel it's a luck game now (& i have no control anymore, but did i to start with?) fs has suggested pgd but feels the odds are in our favour not to go down this path yet due to both our individual karotype tests being normal.

Will transfer embies most likely in sept, working with a TCM lady- doing acupuncture, massage, cupping and taking herbs weekly. So want to give her two AF cycles to see if this helps.

Also had a knee arthroscope today, so will be recovering the next couple of weeks.

…again sorry for long long long post...but I just wanted to capture my background do you know a bit about me and our struggles.

And it would be so nice to be in one consistent thread. So that's my journey so far.

Has anyone telltale signs of miscarrying. I'm convinced my headaches become unbearable when the embryo has passed away and I have a brown discharge. FS said that a brown discharge wouldn't be a usual concern initially (old blood) but it is for me..

I recognise a few names and I'm so excited for kmvw!!

.

hi there, im so sorry for ure long journey, may i ask ure prednisone are u on it for the whole 12 weeks and then ween off??? or only for 5 days pre transfer???? also do u take clexane???? apparently that also helps with the baby aspirin. I too have PCOS and truely believe the prednisone helped me concieve and maintain my pregnancy of my DD, prior to that i did try it for only 5 days and M/C or chem.

Zakmick I knew you had a very tough journey but I didn't know it has been so rough. I wish you all the best and know your luck will change. I've had a tough three years as well, I thought we had been cursed so many bad things happened and kept happening. At some point your luck changes, it will change as it did for us

Can't change the past, but we can learn from it to make us stronger and move forward!

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Thanks for the kind welcome and words of wisdom, that's why I needed to come in here.

I'm with City Fertility in Melbourne DW FS.

Prednisone I'm only on for 5 days from day of transfer, I've asked about being on it longer and he has said a definite no. He believes the side effects are too risky, weight gain (I am overweight), sleeplessness etc.
My arguments for longer prednisone too was that I have allergies (food intolerances) and I have read that the steroids can help strengthen the body and I've been recently diagnosed with heamochromotosis (my body absorbs too much iron).

I asked about the clexane too but at last apt, as we just got back the results from the POC test he said none of the things will change this outcome. Your body wasn't the problem for not hanging on to the embryo it was a chromosome issue. However I kept trying to bring him back to this is the 4th m/c we don't know why the others happened. (wish I had the karotype test completed on the embryo at first d&c, hindsight is a wonderful thing). FS just kept bringing me back to the results and told me to stop googling. It infuriated me a bit as DH sided with him and was happy to just do as last cycle.

When I brought up the fact I was doing TCM, he was dismissive too ( I know he is a science man) but wants me on no herbs etc if I'm stimming, he is happy for acupuncture to continue though, if it relaxes me.

I spoke to my TCM lady and she said what she would do, would compliment the ivf and not work against it- this would be through acupuncture and herbs. Has anyone done this? Continued with herbs as well as the acupuncture?

I only go on progestrone support if it's a medicated cycle i.e. After a stimming cycle or medicated FET. Other than that FS prefers the natural approach, and not too many drugs if it can be avoided. The progestrone gives me migraines too. GRR..

He believes that the progestrone in the uterus reflects differently than the blood, and if it is a healthy embryo that the body will respond accordingly. BT for hcg results are always just beta hcg, he never tests for progestrone.

We did have an apt booked to see Lyn Burmeister at Monash but cancelled due (DH is right too) to that I would not be in the right frame of mine if we met with her before using our 2 frosties with cfc.

I think I will meet with FS once more before sept, and discuss with him my concerns about this being the 4th m/c and why not give clexane a go, there are no side effects/risks from this except the bruising from the injection site (am I right?) there are only gains. It will be an uphill battle, but I was the one initially who got him to consider putting me on the prednisone to start with- not him, and that was through my googling!!

Can't change the past, but we can learn from it to make us stronger and move forward!

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Originally Posted by bubs4kylee

Zakmick - oh my!!! I just read your story and my heart goes out to you. I do recognize you from previous threads over the past 18 mkbths that I have been on........ Oh Hun I wish you all the best for sep. I too recently crossed over to this thread. I feel the monthly threads go to quick and to be honest it's too Dam painful being left behind each month. I'm currently pupo with two, day 3 embryos but I didn't think they looked that good.... This was my 8th transfer. But my 6th full stim. I never get many eggs. DH has dodgy sperm.....
Which clinic are you at if you don't mind me asking??

All the best kylee.

Good luck Kylee, the one thing from this whole journey I have learnt is that not always the best embryos give the desired outcome. The classing of all the embryos etc I think is hard sometimes as it makes us worry before they are transferred, that they are not good quality.
Your embies didn't arrest they were dividing which is what their meant to do. Enjoy being PUPO!!

Zacmick
Iam so sorry that your doctors wont listen to you I had the same problem after my last miscarriage i sat in my ob office and cried and said to her please can we try what I want this time she did agree after my melt down iam now on 25mg prednisiolone from day one of ivf injections and keep going till 12 weeks if i get a bfp and wean back down to 5mg if i dont i use to get the flu and headaches aftet every transfer a sign i think that nk cells are attacking i also take
100mg asprin once a day
5mg folic acid once a day
1000iu vitamin d twice a day
Elevit once a day
Caltrate 600mg once a day
Progesterone pressies after transfer
If i get a bfp i will start on clexane injections
I think it gets to a point where it cant hurt to try anything

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Zacmick
Iam so sorry that your doctors wont listen to you I had the same problem after my last miscarriage i sat in my ob office and cried and said to her please can we try what I want this time she did agree after my melt down iam now on 25mg prednisiolone from day one of ivf injections and keep going till 12 weeks if i get a bfp and wean back down to 5mg if i dont i use to get the flu and headaches aftet every transfer a sign i think that nk cells are attacking i also take
100mg asprin once a day
5mg folic acid once a day
1000iu vitamin d twice a day
Elevit once a day
Caltrate 600mg once a day
Progesterone pressies after transfer
If i get a bfp i will start on clexane injections
I think it gets to a point where it cant hurt to try anything

this is what im on too and what i took when i fell PG with DD.
after reading "is your body baby reading" by dr alan beer, i finally understood what was going on with my ivf journey.

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Any one had a karyotype test that didn't work?? 8 week wait suppose to get results next fri but found out yesterday mine didn't grow in the lab, fs sent out forms to repeat but said it still might not work??? The last few weeks have been torture and now I gotta do it all again have appt next fri to discuss it and dh results but he had said not to do a cycle till we got them back :s

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Originally Posted by moomechanic

Any one had a karyotype test that didn't work?? 8 week wait suppose to get results next fri but found out yesterday mine didn't grow in the lab, fs sent out forms to repeat but said it still might not work??? The last few weeks have been torture and now I gotta do it all again have appt next fri to discuss it and dh results but he had said not to do a cycle till we got them back :s

Sorry no ...8 wk wait that's a long time, ours were back in 5-6wks both the individual and the product of conception test.
FS advised us not to do a cycle until the results came in for the individual tests too..
That's so frustrating, you think they could have called earlier to say they needed another sample, 8 wks is a long time to get back to FS and say your sample didn't grow.. I would very peeved!!

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