Salvia (sage; Lamiaceae), with about 950 species, is one of the largest genera of angiosperms, and displays a remarkable breadth of ecological, geographical, and morphological variation. Salvia occurs on six continents, with major species radiations in East Asia, the Mediterranean region (including southwest Asia), and Mexico-Central/South America, as well as relatively minor species radiations in California and South Africa. It is differentiated from other genera in subtribe Salviinae by possessing only two fertile stamens (as opposed to four), and by most members of the genus having an elongated connective, which has been hypothesized to be responsible, at least in part, for the extraordinary success of the genus. Salvia is also among the most popular genera of horticultural plants. However, despite the widespread distribution and ecological and horticultural importance of Salvia, relationships within the genus remain unclear. This lack of phylogenetic clarity has impeded our ability to understand the evolutionary history of the genus, and resultantly, definitively elucidating the specific morphological characters responsible for the evolutionary success of Salvia has remained elusive. Here we explore phylogentic relationships within Salvia using Anchored Phylogenomics.