Expert advice for Omeprazole

Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.

Omeprazole can decrease magnesium levels in blood. Get your magnesium levels checked regularly. You may need a magnesium supplement or need to discontinue your medicine.

Inform your doctor if you are suffering from osteoporosis as Omeprazole can weaken your bones by decreasing calcium levels in blood. You may need a calcium supplement, preferably calcium citrate.

Omeprazole is a well-tolerated medicine and provides relief for a long time.

It may take a few days to show its effect. You can take an antacid for a quick relief during this time unless your doctor has asked you not to use them.

Once you start feeling better, do not stop taking your medicine. Take it for the duration as advised by your doctor

Warnings

Special precautions for Adom 10 mg/20 mg Tablet

Alcohol

CAUTION

Taking a large amount of alcohol can increase acidity and ca

use acid reflux in the food pipe causing heartburn. This would decrease the effect of this drug and can aggravate your underlying condition.

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Pregnancy

WEIGH RISKS VS BENEFITS

Adom 10 mg/20 mg Tablet may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

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Lactation

Adom 10 mg/20 mg Tablet is probably safe to use during lacta

tion.
Limited human data suggests that the drug does not represent a significant risk to the baby.

Frequently asked questions for Adom 10 mg/20 mg Tablet

Frequently asked questions for Domperidone

Domperidone is used for the treatment of nausea (feeling sick) and vomiting as and when recommended by your doctor.

Q. Is Domperidone an over the counter drug?

Domperidone is not an over the counter (OTC) medicine and it is not advisable to take it without a prescription.

Q. Does Domperidone cause weight gain?

Weight gain has not been reported with the use of Domperidone. If you notice any abnormal weight gain while using Domperidone, please talk to your doctor.

Q. Does Domperidone raise the blood pressure?

The increase in blood pressure is generally not seen with the use of Domperidone. But if you experience an increase in blood pressure while using Domperidone, please consult your doctor.

Q. Can I take Domperidone for morning sickness?

Domperidone is not indicated or recommended for treating morning sickness. Please consult your doctor if you plan to take any medicine for treating morning sickness.

Q. Can I take Domperidone with antibiotics?

The use of Domperidone with antibiotics like erythromycin, levofloxacin, moxifloxacin, spiramycin, and some antifungals is not recommended. Please consult your doctor before using any antibiotics with Domperidone.

Q. Can I take Domperidone with lansoprazole?

Yes, Domperidone can be taken with lansoprazole as no drug-drug interactions have been clinically seen when they are taken together. However, interactions may occur. Please consult your doctor before using the two medicines together.

Q. Can I take Domperidone with doxycycline?

Yes, Domperidone can be taken with doxycycline. No drug--drug interactions have been reported. However, please consult your doctor before taking Domperidone with doxycycline.

Q. Can I take Domperidone with omeprazole?

Yes, Domperidone can be taken with omeprazole. No drug--drug interactions have been reported. However, interactions may occur. Please consult your doctor before using the two medicines together.

Q. Can I take Domperidone with citalopram?

The use of Domperidone with citalopram is not recommended as it may increase the underlying heart problems like prolonged QTc interval. Please consult your doctor before taking the two medicines together.

Q. Can I take Domperidone with amitriptyline?

Yes, Domperidone can be taken with amitriptyline. No drug--drug interactions have been reported. However, please consult your doctor before taking Domperidone with amitriptyline.

Q. Can I take Domperidone with amoxicillin?

Yes, Domperidone can be taken with amoxicillin. No drug-drug interactions have been reported. However, please consult your doctor before taking Domperidone with amoxicillin.

Q. Can I take Domperidone with paracetamol?

Yes, Domperidone can be taken with paracetamol. No drug--drug interactions have been reported. However, interactions may occur. Please consult your doctor.

Q. Can I take Domperidone with tramadol?

Yes, Domperidone can be taken with tramadol as no drug--drug interactions have been reported. However, please consult your doctor before taking Domperidone with tramadol.

Q. Is Domperidone safe?

Yes. Domperidone is safe if used at prescribed doses for the prescribed duration as advised by the physician/ doctor.

Q. Is Domperidone used for motion sickness?

Domperidone is indicated for use in motion sickness. Please consult your doctor before using Domperidone for motion sickness as it must be used in the dose and duration as advised by your doctor.

Q. Is Domperidone an antibiotic?

No, Domperidone is not an antibiotic. Domperidone is an anti-emetic which is used to treat nausea (feeling sick) and vomiting (being sick).

Q. Does Domperidone cause drowsiness?

Drowsiness has been reported as one of the rare side effects with Domperidone. Please talk to your doctor if you experience excessive drowsiness while taking Domperidone.

Q. Does Domperidone increase milk secretion?

Yes, Domperidone can increase milk secretion also known as galactorrhea. This is an uncommon side effect of Domperidone. Talk to your doctor if you are experiencing this side effect while taking this medicine.

Q. Does Domperidone cause bloating (gas)?

Domperidone can cause some uncommon gastrointestinal side effects like regurgitation, appetite disorder, and heartburn, diarrhoea. However, bloating (gas) has not been reported as a side effect with Domperidone.

Q. Does Domperidone cause hair loss?

Domperidone has not been reported to cause hair loss. Please consult your doctor in case you experience excessive hair loss while taking Domperidone.

Q. Does Domperidone help to treat constipation?

Domperidone is not indicated to treat constipation. Please talk to your doctor regarding its use.

Q. Does Domperidone cause heart problems?

Domperidone may be associated with an increased risk of heartbeat problem and heart attack. This risk may be more likely in those over 60 years old or taking higher doses. The risk also increases when Domperidone is given together with other medicines. Please share your medical history with your doctor if you are prescribed Domperidone.

Q. Does Domperidone cause constipation?

Yes, Domperidone has been seen to cause constipation as a side effect.Consult your doctor if you experience excessive constipation while using Domperidone.

Q. Does Domperidone help to relieve bloating (gas)?

Domperidone is an anti-emetic which is used to treat nausea (feeling sick) and vomiting (being sick). It is not indicated to treat bloating (gas). Please consult your doctor before using this medicine.

Q. Can I take Domperidone with rabeprazole?

Domperidone can be safely taken with Rabeprazole as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone increases gut motility and Rabeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.

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Frequently asked questions for Omeprazole

Q. Can I take Omeprazole with domperidone?

Omeprazole can be safely taken with domperidone as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone works by increasing the gut motility and Rabeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.

Q. What are the various conditions in which the use of Omeprazole is contraindicated?

Use of Omeprazole is contraindicated if you are allergic to this medicine or any other medicine belonging to the same class of drugs. Also, do not take Omeprazole if you are already taking a medicine containing nelfinavir (used for the treatment of HIV infection).

Q. What if I miss my dose of Omeprazole?

If you miss a dose of Omeprazole, take it as soon as you remember and the next dose as scheduled. However, if it is almost the time for your next dose, skip the missed dose and take your next dose and then follow the regular schedule. Do not take double the dose.

Q. Can I take Omeprazole along with oral contraceptive pills (birth control pills)?

Omeprazole can be safely taken with oral contraceptive pills (birth control). They do not affect each other's action and no harmful effects have been seen when they are used together.

Q. What is Omeprazole?

Omeprazole belongs to the group of medicines known as proton pump inhibitors (PPIs). This drug decreases the acid production in your stomach and is indicated for the treatment of conditions caused by excess acid secretion in the stomach.

Q. Is Omeprazole better than pantoprazole?

Omeprazole and pantoprazole both belong to the same class of drugs and are used in disease conditions with excess acid production like heartburn, acidity, stomach ulcers and intestinal ulcers. Both work by decreasing acid production in the stomach and are seen to be almost equally effective and safe in many clinical research studies. However, the response may vary from patient to patient and depend on the dose.

Q. Can Omeprazole cause subacute cutaneous lupus erythematosus?

Omeprazole has been reported to cause subacute cutaneous lupus erythematosus in many studies. Common signs and symptoms of this disease include painful joints, tiredness, weakness, rash, fever, anemia, mouth ulcers, hair loss, and many others and these may get aggravated again and again. Talk to your doctor if you experience these side effects as you may need to discontinue this medicine.

Q. Is Omeprazole better than lansoprazole?

Omeprazole and lansoprazole are two different medicines belonging to the same class 'proton pump inhibitors'. Some studies mention that lansoprazole is more effective than Omeprazole for rapid relief of symptomatic heartburn. However, the effect of these medicines may vary upon individual response.

Q. Is Omeprazole better than probiotics?

Probiotics and Omeprazole perform different functions in the body. Omeprazole suppresses acid production in the stomach to prevent injury to the walls of the stomach and esophagus while probiotics help to prevent the overgrowth of harmful bacteria in the body, help to maintain a balance in the stomach between good and harmful bacteria and protect the stomach from infections. Probiotics and Omeprazole both are useful in the eradication of helicobacter pylori, which can cause stomach ulcers and also contribute to acid reflux.

Q. Can I take Omeprazole with ondansetron?

Ondansetron is an anti-emetic medicine which helps in relieving nausea (feeling sick) or vomiting. No harmful effects have been seen when Omeprazole is used with ondansetron. So, these two medicines can be taken together.

Q. Can Omeprazole cause lactose intolerance?

Lactose intolerance has been reported with the use of Omeprazole in some patients. Many Omeprazole preparations contain lactose as an ingredient. This is a digestive problem in which the patient cannot digest lactose, a type of sugar mainly found in milk and dairy products. The patient may complain of symptoms like flatulence (gas), diarrhea, bloating, stomach pain and feeling of being sick (nausea). Read the ingredients mentioned on the pack before taking the medicine.

Q. Can I take Omeprazole with Vitamin E?

Omeprazole can be taken with vitamin E. The combinations seems to have a beneficial effect in terms of better maintenance of moderate to severe esophagitis. However, there are not many studies or reports on this subject. Talk to your doctor for more information on this.

Q. Can I take Omeprazole with levosulpiride?

Omeprazole can be safely taken with levosulpiride as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Levosulpiride works by increasing the gut motility and Omeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.

Q. Is Omeprazole better than famotidine?

Omeprazole is a proton pump inhibitor (PPI) and famotidine is an H2 blocker. Both lowers the amount of acid in your stomach, treats heartburn, and heals ulcers. Studies have shown that Omeprazole is more effective than famotidine for the control of gastro-oesophageal reflux disease symptoms, in rapid healing of duodenal ulcers and achieving more rapid pain relief. However, the effect of these medicines may vary upon individual response.

Q. Does Omeprazole use increase the risk of clostridium difficile infection?

Use of proton pump inhibitors (PPIs) like Omeprazole may be associated with an increased risk of Clostridium difficile–associated diarrhea (CDAD) as reported in few studies and informed by the US FDA as well. A possibility of CDAD can be there in patients taking PPIs and developed diarrhea that does not improve.

Q. Can Omeprazole be used in cancer patients?

Omeprazole can be taken by cancer patients as prescribed by a doctor. Since cancer patients may also take many other medicines for the primary cancer treatment or for other symptoms and infections, there are chances of drug interactions with Omeprazole.

Q. For how long can Omeprazole be taken?

Take Omeprazole for as long as advised by your doctor. The duration of taking Omeprazole would vary depending on your condition. Do not stop taking this medicine without talking to your doctor.

Q. Can Omeprazole cause calcium deficiency and osteoporosis?

Omeprazole can cause osteoporosis (thinning of bones) as it decreases the calcium absorption leading to calcium deficiency. This leads to an increased risk of bone fractures on long-term use, like hip, wrist or spine fractures. Inform your doctor if you have osteoporosis or if you are taking corticosteroids (these can increase the risk of osteoporosis) before starting your therapy. Take enough calcium and vitamin D to reduce the risk.

Proton (acid) pumps are found on the stomach mucosa and they are responsible for secreting acid in the stomach. Omeprazole works by blocking this gastric acid pump and this unique mechanism of action helps in decreasing the acid secretion in the stomach.

Q. Does Omeprazole cause hepatitis B and can a patient of hepatitis take Omeprazole?

Omeprazole can rarely cause hepatitis with or without jaundice and very rarely it can lead to hepatic failure and encephalopathy in patients with the underlying liver disease. Omeprazole does not cause hepatitis B or any other viral hepatitis. However, there are studies showing an increased occurrence of hepatic encephalopathy in hepatitis B patients using PPIs. These medicines should be used with caution in patients with the underlying liver disease.

Q. Is Omeprazole better than dexlansoprazole?

Omeprazole and dexlansoprazole are two different medicines belonging to the same class of proton pump inhibitors. There are no studies which compare Omeprazole and dexlansoprazole. Omeprazole and dexlansoprazole have similar action, but their effect may vary in different patients.

Q. Does Omeprazole increase chromogranin levels?

Use of proton pump inhibitors like Omeprazole has been seen to be associated with an increase in chromogranin levels. This increase in chromogranin levels can be due to the effect of these drugs on enterochromaffin cells and this could also falsely increase the levels in patients with neuroendocrine tumours.

Q. Does Omeprazole cause dementia?

Use of proton pump inhibitors like Omeprazole has been recently linked with the development of dementia in elderly patients. As this risk of developing dementia is not confirmed, talk to your doctor for more information on this effect.

Q. Does Omeprazole cause vitamin deficiencies?

Omeprazole may cause vitamin B12 and vitamin C deficiency. When taken orally, vitamin B12 requires an acidic environment for its absorption from the stomach while Omeprazole causes a decrease the gastric acid secretion. You may need to take vitamin B12 supplements from outside. The clinical significance of the decrease in vitamin C levels is not known, so vitamin C supplementation is not recommended.

Q. Does Omeprazole have an expiry date?

Yes, Omeprazole does expire. Please check the expiry date written on the pack and it refers to the last day of that month. Do not use Omeprazole after the expiry date.

Q. What is the role of Omeprazole before endoscopy in patients with gastrointestinal bleeding?

Omeprazole before endoscopy in patients with gastrointestinal bleeding reduces the need for endoscopic therapy, the rate of post-endoscopy bleeding, and shortens hospital stays. Hence Omeprazole is given before endoscopy in patients with gastrointestinal bleeding.

Q. Is Omeprazole better than ranitidine?

Omeprazole is a proton pump inhibitor (PPI) and ranitidine is an H2 blocker. Both lowers the amount of acid in your stomach, treats heartburn, and heals ulcers. Studies have shown that Omeprazole is more effective than ranitidine in resolving heartburn in patients with gastroesophageal reflux disease (GERD), rapid healing of ulcers and prevent ulcers in patients who use nonsteroidal anti-inflammatory drugs (NSAIDs). However, the effect of these medicines may vary upon individual response.

Q. Are there any withdrawal symptoms associated with the use of Omeprazole?

There are no withdrawal symptoms seen when patients stop using Omeprazole as it has no habit forming tendencies.

Q. Can Omeprazole cause magnesium deficiency?

Omeprazole can cause magnesium deficiency in the blood. Low magnesium levels is a rare side effect seen in patients treated with Omeprazole for at least three months and in most cases after a year of therapy. The patient may have symptoms like tetany, arrhythmias, and seizures and may need to stop this medicine and take magnesium from outside. Magnesium levels should be tested at regular intervals in the patients taking Omeprazole for a long duration.

Q. Is Omeprazole a controlled substance?

Omeprazole is not a controlled substance. It is available when prescribed by a doctor.

Q. Can Omeprazole be used in cardiac patients?

Patients with cardiac disease can take Omeprazole. However, Omeprazole can interact with certain drugs (e.g clopidogrel, digoxin) which might be used by a patient with an underlying cardiac disease. Patients taking Omeprazole and digoxin may need to be monitored for digoxin toxicity. Omeprazole decreases the activation of clopidogrel, thus reducing its effects. Patients taking these medicines together needs to be monitored closely by a doctor.

Q. Can the use of Omeprazole cause iron deficiency?

Use of Omeprazole can cause iron deficiency and a decrease in hemoglobin levels as it decreases the acidic environment of the stomach needed for the absorption of iron. However, there are no recommendations on the regular monitoring of iron levels or taking iron supplements when the patient is taking Omeprazole.

Q. How is Omeprazole different from esomeprazole?

Omeprazole and esomeprazole both belong to the same class of drugs and are used in disease conditions with excess acid production like heartburn, acidity, stomach ulcers and intestinal ulcers. Esomeprazole is an S-isomer of Omeprazole. Studies have shown that esomeprazole provides more effective and rapid acid control than Omeprazole, without any increase in side effects and fewer variations in response between different patients.

Q. Is Omeprazole a narcotic substance?

Omeprazole is a not a narcotic substance and has not been reported to have any abuse potential. Omeprazole does not get you high and does not cause any addiction as no withdrawal symptoms have been reported when you stop taking this drug.

Q. Is Omeprazole available without a prescription as an over the counter product?

Omeprazole is a prescription medicine and you can buy this drug by providing a doctor's prescription. Omeprazole is not available as an over the counter (OTC) product.

Q. How is Omeprazole metabolised in the body?

Omeprazole is metabolized in the liver by the cytochrome P450 enzymes mainly CYP2C19. There could be an increase in the level of Omeprazole in patients with underlying liver disease because of a decrease in its metabolism. However, the amount of drug does not increase if given once a day.

Q. Can Omeprazole be used in stroke patients?

Omeprazole can be used in stroke patients. There are studies suggesting that proton-pump inhibitors (PPIs) as a class are not associated with an increased short-term risk of recurrent stroke or death among older adults treated with clopidogrel after stroke.

Q. How is Omeprazole better than cimetidine?

Omeprazole is a proton pump inhibitor and cimetidine is an H2 receptor blocker. They act in different ways but both decrease the acid production in the stomach. However, Omeprazole is more potent, longer acting, and has fewer adverse effects when compared to cimetidine.

Q. Is Omeprazole better than rabeprazole?

Omeprazole and Rabeprazole belong to the same class of medicines known as proton pump inhibitors (PPIs) and work in the same way to decrease acid production in the stomach. However, few clinical studies have shown that rabeprazole provides better relief of the symptoms including the daytime pain of duodenal ulcers. The difference in response may also vary in different patients