Vanguard is one of the best, especially if you believe in the investing philosophy of indexing. What do you use them for? Taxable investing? Ira/Roth Ira? ETFs? The Vanguard brokerage platform is free if you use it to buy their ETFs. If you do a lot of trading and have substantial assets the Wells Fargo wellstrade seems to be the best brokerage platform.

The most important part of investing: make a plan, actually do the plan, ignore the noise.