CONTRA-INDICATIONS:In patients with renal impairment.Hypersensitivity to any tetracycline.Oxytetracycline should not be given in pregnancy, lactation and in
young children.

WARNINGS:Use with care in patients with liver function impairment;Do not use concomitantly with hepatotoxic medicines;Tooth discolouration , enamel hypoplasia and retarded bone growth
may occur in children under the age of 12 years. These effects may
also occur in the foetus if given to prenant women;Symptoms of myasthenia may be aggravated;Photosensitivity may occur (see " Side effects and Special
Precautions");Pseudotumor cerebri may occur.

DOSAGE AND DIRECTIONS FOR USE:Oxytetracycline should be taken either one hour before meals or two
hours after meals. The maximum dose for oxytetracyline should not
exceed 3g daily for adults and 50mg/kg bodymass/day for children.The usual dose for oxytetracycline for the commonly occurring
infection , depending on the severity is 250 to 500 mg every six
hours.For acne , the adult dosage is as follows: 250mg twice daily

SIDE EFFECTS AND SPECIAL PRECAUTIONS:Oxytetracycline is not indicated for treating commonly occurring
infections in children under 12 years of age.Gastro-intestinal: Nausea, Vomiting , Diarrhea , Glossitis ,
Dysphagia related to oesophagitis.Secondary fungal overgrowth (Candida Albicans): Oral candidiasis,
Vulvovaginitis, pruritus aniSecondary bacterial overgrowth infections may occur.Resisitant coliform organisms such as Proteus spp. may cause
diarrhea.Supper-infection due to resistant staphylococci may cause
fulminating enteritis.Increased severity of uraemia and hepatotoxicity in patient with
renal disease given high doses.