Burdo operated along the Atlantic coast carrying out training exercises and mock landings during December 1945 through October 1948, with the exception of three trips to the Caribbean. On 1 November 1948, in company with other units of the Atlantic Fleet, Burdo departed Norfolk en route to NS Argentia, Newfoundland, for cold weather operations. On 20 November, she returned to Norfolk and continued with her Atlantic and Caribbean operations until May 1951.

In May 1951, she became a unit of the Midshipmen Practice Squadron, and participated in the midshipmen summer cruise to northern Europe and the Caribbean, returning to Norfolk at the end of July. After overhaul, she resumed training exercises in cooperation with the Marines. Early in January 1953, Burdo was assigned to the 6th Fleet, and operated as a unit of the Amphibious Group until May 1953. During this assignment, she participated in one of the first NATO exercises.

Over the next several years, Burdo engaged in amphibious operational training along the eastern seaboard, conducted six Caribbean training cruises, and had another tour with the 6th Fleet.