Proton pump inhibitors and fracture risk. The HUNT study, Norway

Osteoporosis InternationalNov 24, 2019

Hoff M, Skovlund E, Skurtveit S, et al. - Data from the Nord-Trøndelag Health Study, The Fracture registry in Nord-Trøndelag, and the Norwegian Prescription Database, comprising of 15,017 women and 13,241 men aged 50–85 years were used in order to determine whether proton pump inhibitors (PPIs) and fracture risk were associated with each other. A total of 266 women and 134 men had a first hip fracture and 662 women and 127 men, a first forearm fracture, during a median of 5.2 years follow-up. Using PPIs, the proportion of females and males was 17.9% and 15.5%, respectively. Thus, it was noted that the use of PPIs was not related to a heightened risk of fractures.

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