In the Spring of 2066, with global oil resources diminishing and China's fossil fuel dependency causing an energy crisis in the nation, China became more aggressive in its trade talks with the United States. With the United States unwilling to export oil to China, Chinese-American relations turned for the worse.

2077年10月23日 - 大戰爆發，a massive nuclear exchange between the nuclear powerhouses of the world. 兩個小時以內，世界毀滅了。Both China and the United States are left severely destroyed and inoperable beyond Old World standards.

During and after the war the North American and East Asian continents suffered greatly. The most significant political consequences of the war in the United States were the Canadian annexation, the Canadian resistance and protests, and riots prompted by food shortages which resulted in the declaration of martial law. The conflict culminated in a nuclear exchange that would become known as the Great War. In a sense, the Sino-American war ended in stalemate as both sides were deprived of resources, suffered enormous military and civilian casualties and were ultimately decimated by total nuclear war.