30 COPE: COlchicine for acute PEricarditisNNT= 5Corticosteroid therapy:RecurrencesOR 4.3095% CI 1.21 to 15.25; p=0.024Here we can see the main results of the study. The primary end point was the recurrence rate. Colchicine reduced the recurrence rate at 18 months down to 11% and was also able to reduce the symptoms persistence at 72 hours as it can be observed in pts with a gouty attack. Drug withdrawal was recorded in about 8% of cases due to diarrhea. Thus in this study we need to treat 5 pts with colchicine in order to prevent 1 recurrence. In multivariate analysis, corticosteroid therapy was an independent risk factor for recurrences.Drug withdrawalImazio M et al. Circulation 2005; 112(13):