OVERDOSE

Measures to be taken are immediate lavage of the stomach and injection of physostigmine
0.5 to 2 mg intravenously and repeated as necessary up to a total of 5 mg. Fever
may be treated symptomatically (tepid water sponge baths, hypothermic blanket).
Excitement to a degree which demands attention may be managed with sodium thiopental
2% solution given slowly intravenously or chloral hydrate (100-200 mL of a 2%
solution) by rectal infusion. In the event of progression of the curare-like
effect to paralysis of the respiratory muscles, artificial respiration should
be instituted and maintained until effective respiratory action returns.