Using simulation to refine DNA microarraysDNA microarray technology has transformed genomics — the study of genes and their function — by enabling scientists to monitor the expression of thousands of genes simultaneously. Microarrays are slides patterned with thousands of microscopic spots containing DNA molecules, or probes. Each probe is designed to hybridize uniquely to one DNA sequence, or target. As targets hybridize to probes, the various regions on a chip become fluorescent.