CPTC-GMNN-3 Evaluation by the Human Protein Atlas

Characterization SOP Files

Background

NCI Identification Number:

10987

Antigen Name:

Geminin

CPTC Name:

CPTC-GMNN

Keywords:

Gem; OTTHUMP00000039393; RP3-369A17.3; geminin

Function:

Inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.