The San Diego Holiday Inn Express Hotel in Otay Mesa welcomes you!

This choice San Diego hotel is nestled in the heart of the Otay Mesa Industrial Business Park, a short drive from downtown San Diego and less than a mile from beautiful Tijuana, Mexico.

Our new hotel in San Diego offers a convenient suburban location near the Sleep Train Wireless Amphitheatre, SeaWorld Aquatica, SeaWorld, the Chula Vista Olympic Training Park and the famous San Diego Zoo. Your family can learn
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The San Diego Holiday Inn Express Hotel in Otay Mesa welcomes you!

This choice San Diego hotel is nestled in the heart of the Otay Mesa Industrial Business Park, a short drive from downtown San Diego and less than a mile from beautiful Tijuana, Mexico.

Our new hotel in San Diego offers a convenient suburban location near the Sleep Train Wireless Amphitheatre, SeaWorld Aquatica, SeaWorld, the Chula Vista Olympic Training Park and the famous San Diego Zoo. Your family can learn about local history at the Cabrillo National Monument, the Air and Space Museum and the Maritime Museum. For some great bargains, check out Las Americas Premium Outlets with 125 outlet stores and 13 restaurants in a lovely outdoor setting, or try the Otay Town Center Mall, just four miles from our San Diego hotel.

Business travelers will enjoy a stay at our San Diego hotel because of its convenient location near companies such as Toyota, Bose, Panasonic, Maxwell, Tyco, JVC, Siemens Medical and Samsung, each within six miles of our San Diego hotel in the Otay Mesa Industrial Park. The International Commercial Border Crossing is .25 miles away. The Brown Field Municipal Airport is three miles away.

Guest Reviews

Rated 5.0 out of 5.0 by Cullenab Great Place to Stay
This is a very nice hotel, they have a very large breakfast and my room was very clean and up to date. Highly recommended!
July 24, 2015

Rated 5.0 out of 5.0 by Soccer Aunt Great stay
I lean towards Holiday Inn brand hotels mainly for the amenities - refrigerator, microwave, pool. Great for tournament weekends. Very kid friendly.
July 21, 2015

Rated 1.0 out of 5.0 by Bugsgalore Bugs galore
Stayed at location to attend Comic-Con. Horrendous experience. My daughter and I were eaten alive by bugs. Hotel Management was informed the morning after and again at checkout. No attempts were made to make amends or change room. Manager had the "too bad so sad" attitude. I was unable to find another place to stay due to Comic-Con Convention filling up hotel rooms in area. Brought up issue of bugs again at checkout. Manager stated, "You must have gone to the beach". I didn't want to waste my time arguing with someone who obviously has no business being in the hotel industry. I had a long drive home. Also on one of the morning they interrupted our stay by sending a crew of people to take measurements of our room. I don't know why they they did that at such a time. Worst stay ever, will never stay there againnor possibly with this chain. Been a member for years and staying exclusively with them for 10+ years. This was absolutely the worst. I documented by bites with picturtes my wife and I took. This is my third attempt at writing this review, they keep rejecting it.
July 21, 2015

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