Over 400 cities worldwide will see millions marching against the US chemical and agricultural company Monsanto in an effort to boycott the use of Genetically Modified Organisms in food production.

Marches are planned in 52 countries in addition to some 47 US states that are jointing in the protest.

“MAM supports a sustainable food production system. We must act now to stop GMOs and harmful pesticides,” said Tami Monroe Canal, founder of March Against Monsanto (MAM) in a press release ahead of the global event.

The movement was formed after the 2012 California Proposition 37 on mandatory labeling of genetically engineered food initiative failed, prompting activists to demand a boycott of the GMO in food production.

The main aim of the activism is to organize global awareness for the need to protect food supply, local farms and environment. It seeks to promote organic solutions, while “exposing cronyism between big business and the government.”

Activists claim that Monsanto spent hundreds of millions of dollars to “obstruct all labeling attempts” while suppressing all “research containing results not in their favor.”

Birth defects, organ damage, infant mortality, sterility and increased cancer risks are just some of the side-effects GMO is believed to cause.

“That is what the scientists have learned about, that the genetically modified foods will increase allergies that they are going to be less nutritious and that they can possibly or very contain toxins that can make us ill,” Organic Consumers Association’s political director Alexis Baden-Mayer told RT.

GMOs have been partially banned in a number of countries, including Germany, Japan, and Russia but yet in most countries across the globe still feed GMOs to their animals.

Citing the US example, Baden-Mayer told RT that “it is hard to distinguish the company Monsanto from the players in the US government.”

“Most of the genetically modified crops grown in the US, almost all of them end up in factory farms, concentrated in animal feeding operations,” stating that US has enough grassland to pasture and raise “100 percent grass-fed beef” and produce even more grass fed beef than is raised on “modified corn and soy.”

One year ago over 2 million people in 436 cities in 52 countries worldwide marched against the largest producer of genetically engineered seeds.