Even people without skin conditions can develop one especially if they've covered in glue and latex for hours at a time day after day. The actor who played Rev Bem on Andromeda had to quit the show because his skin couldn't handle the make up any longer. Kes grew longer hair so Jennifer Lein could stop wearing the ears because her skin became to sensitive to the glue. If you have a skin condition of some kind to begin with you might not even be able to handle it in the first place.

And let's not forget Virginia Hey as Zhaan on Farscape, and that was just paint, no latex or glue, because she shaved her head and eyebrows for the part