Factors affecting contraceptive use among married women of reproductive age in Bangladesh

AbstractAflatoxins cause health burden in feed chain particularly in tropical areas of the world, causing great health hazards to animals and in advance, to human. Currently, there is no universal measure to detoxify aflatoxins in contaminated feeds to render them safe. The study aimed to evaluate potential of crude clays and ashes as test binding materials (TBM) in binding aflatoxins in solution, towards reducing their toxicity to animals ingesting aflatoxin contaminated feeds. Using in-vitro technique, clays designated AC, KC, CC and MC and ashes VA and RA were evaluated for their capacity to bind aflatoxins B1 (AFB1), B2 (AFB2), G1 (AFG1) and G2 (AFG2) relative to a commercial binder MycobinderR (Evonik) as a reference. On average, CC, VA, KC, MC, AC, RA and MycobindR were able to bind 39.9%, 51.3%, 61.5%, 62.0%, 72.6%, 84.7%and 98.1% of the total aflatoxins in buffered solution, respectively. The capacity of AC and RA was statistically (p<0.05) equal and potentially high in binding aflatoxins next to the MycobindR. The capacity trend of the TBM and MycobindR to bind aflatoxins, largely seemed to follow the trend of their cation exchange capacity (CEC). The CEC (meq/100g) varied as 7.0, 15.4, 18.8, 25.4, 27.2, 27.2 and 38.9 for CC, MC, KC, VA, AC, RA and MycobindR, respectively. The Average proportions of AFB1, AFB2, AFG1 and AFG2 adsorbed to the TBMs were 96.3%, 42.7%, 80.8% and 32.1%, respectively. The binding capacity of the TBM relative to MycobindR was about 100% for AC and RA, 50% for KC, MC and VA and 33.3% for CC. The AC and RA seem to be promising resources in binding aflatoxins and can be utilized in alleviating aflatoxin contamination of feeds.

Devreese, M. (2013). Development of in vitro and in vivo models for testing the efficacy of mycotoxin detoxifying agents and their possible interaction with oral absorption of veterinary drugs (Doctoral dissertation, Ghent University).

Kolosova, A. and Stroka, J. (2012). Evaluation of the effect of mycotoxin binders in animal feed on the analytical performance of standardised methods for the determination of mycotoxins in feed. Food Additives & Contaminants: Part A, 29(12), 1959-1971.​https://doi.org/10.1080/19440049.2012.720035