Summary: We show that bone morphogenetic protein and nodal drive epithelial-mesenchymal transition (EMT) and invasiveness in melanoma cells, induce EMT and a melanoma-like invasive phenotype in melanocytes.

Summary: We describe a novel role for BMP activity in promoting a direct and cell type-independent mechanism for apical constriction, cell elongation and epithelial invagination, separate from acquisition of placode-specific identities.