3 AbbVie… Who We are?A leading global biopharmaceutical company one year old, but carrying 120 years history in research.AbbVie aspires to contribute to Healthcare Sustainability via Innovative Medicines and New Healthcare Solutions.(Chicago Based company)

4 Responsibly active member of the communityAbbVie Way!Leading biopharmaceutical company in the life sciences industry that fosters pharma innovation & competitivenessa long-term, reliable Partner and a key contributor to the economy and healthcare sustainabilityResponsibly active member of the community

5 AbbVie Part of the Innovative Biopharmaceutical IndustryThe innovative biopharmaceutical industry represents global leading pharmaceutical research and biotechnology companiesOur companies are devoted to discovering new medicines that allow patients to live longer, healthier, and more productive livesIn 2009, the biopharmaceutical sector invested approximately $65.3 billion in research and development

6 Biopharmaceutical Companies’ Investment in R&D Increasing Steadily“Total Biopharmaceutical Company R&D andPhRMA Member R&D: 1995–20081The pharmaceutical industry is one of the most research-intensive industries in the United States. Pharmaceutical firms invest as much as five times more in research and development, relative to their sales, than the average U.S. manufacturing firm.2— Congressional Budget Office“Sources: 1Burrill & Company, analysis for PhRMA, 2005–2009; Pharmaceutical Research and Manufacturers of America, PhRMA Annual Member Survey (Washington, DC: PhRMA, ); 2CBO, Research and Development in the Pharmaceutical Industry, 2006.66

10 How we can help? Technology and knowledge transferImprove patient access to innovative medicines and as results improve patient outcomesImprove efficiency of healthcare deliveryAnticipate in boosting the economy by local investmentsTechnology and knowledge transferCreate high quality jobs

11 Improve patient access to innovative medicines and as results improve patient outcomesPrescription medicines play a major role in saving and improving livesOver the last 25 years, prescription medicines have significantly reduced deaths from major diseases such as heart disease, several cancers, and HIV /AIDSImproved the quality of lives of people suffering from conditions such as arthritis disease. Currently we are talking about full remission from Many Immune Diseases such as Crohn’s, Rheumatoid Arthritis, Psoriasis, Parkinson, needless to mention the prematurity solutions for babies…etc…Recent advances include a new generation of personalized medicines, treatment for some rare diseases and cure for infections like Hepatitis C.

12 Major Advances in Treatment and PreventionSince 1980 life expectancy for cancer patients has increased by 3 years. Research finds that medicines alone account for 50-60% of survival increases.Thanks in part to new medicines, heart failure and heart attack deaths fell by 45% in just the last decade.Within three years of introduction of the first antiretroviral treatments, HIV/AIDS deaths dropped by nearly 70%.“The rapid increases that have been observed in drug-related R&D spending have been accompanied by major therapeutic gains in available drug treatments.”CBO, 2006E. Sun, et al., “The Determinants of Recent Gains in Cancer Survival: An Analysis of the Surveillance, Epidemiology, and End Results (SEER) Database,” Journal of Clinical Oncology, May 2008 Suppl (Abstract 6616).F. Lichtenberg, “The Expanding Pharmaceutical Arsenal in the War on Cancer,” NBER Working Paper 10328, February, 2004.K. A. Fox, et al., “Decline in Rates of Death and Heart Failure in Acute Coronary Syndromes, ,” Journal of the American Medical Association (JAMA) 297, no. 17 (2007):CASCADE Collaboration, “Determinants of Survival Following HIV-1 Seroconversion After Introduction of HAART,” The Lancet 362 (2003):12

15 How we can help? Technology and knowledge transferImprove patient access to innovative medicines and as results improve patient outcomesImprove efficiency of healthcare deliveryAnticipate in boosting the economy by local investmentsTechnology and knowledge transferCreate high quality jobs

17 Some Real Life Examples of Health Education– IMID CongressIMID – Immune Mediated Inflammatory Disorders Congress 5% -7% MEA population is afflictedTreated and managed by multi-specialists like Rheumatologists, Dermatologists, Gastroenterologists, Ophthalmologists and Internists who have little time and opportunity to communicate with each other.IMID Congress created a multispecialty platform to bring these specialists together to discuss the latest developments and research to achieve improved patient outcomes. Result: Increased referrals of patients across the specialties that facilitates better co-management of patients.

19 Some Real Life Examples of what we did – Academy of ImagingAbbVie partnered with GENERAL Electric to support continuous education of Rheumatologists who were interested in learning ultrasound of the joints. This education was the first of its kind in the MEA and helped to improve the standard of care of the RA patients and support the physician in diagnosis and monitoring of the disease.Result: Rheumatologists started using US in practice and ultrasound became increasingly recognized as a standard tool for diagnosing and treating the aggressive disease early.

21 Some Real Life Examples of what we did – Patient Support ProgramPatient Support Specialists (trained physicians and pharmacists by qualification) educate patients on disease understanding and elevate awareness on possible detrimental outcomes if left untreated.In addition:Organize patients’ days whereby consultants areinvited to educate patientsAdvise patients to follow up with PhysiotherapistsOrganize meetings of patients with Nutritionists to learn about optimal diet regime.Facilitate appointment with Psychiatrists for the depressed Ps patients if neededThe program is endorsed by MOH and Health AuthoritiesReceived endorsement of the Her Royal Highness Princess Oraib Al Saud (daughter of HH Saudi King) to endorse a valuable program aimed to raise prematurity awareness and to call for action to set the healthcare standards of Neonatology in Saudi.The program is supported by many other corporate partners.

22 How we can help? Technology and knowledge transferImprove patient access to innovative medicines and as results improve patient outcomesImprove efficiency of healthcare deliveryAnticipate in boosting the economy by local investmentsTechnology and knowledge transferCreate high quality jobs

37 We need Common understanding!Common Interest and Better understanding of each other needsOpen DialogueTransparencyTrust

38 Improving Patients’ Health and Quality of Life“New drugs allow children with rheumatoid arthritis to walk and to go to school. New drugs shrink cancerous tumors and they control the advance of HIV. They prevent or halt heart disease, slow the progression of multiple sclerosis, and cure infectious diseases.” 13—Mark B. McClellan, M.D., Ph.D., Then-FDA Commissioner,September 2003Innovative medicines not only extend life but also make life itself betterfor patients. New medicines can improve quality of life for patientssuffering from long-term illnesses or help patients remain independent bypreventing disability. Patients’ lives are often improved by medicinesbecause the medicines can avert complications or limit the severity of asickness. For example:• Increasingly, researchers and clinicians are turning their attention totargeted therapies, which attack cancer cells while avoiding healthyones. These medicines are generally given in the form of pills ratherthan as intravenous (IV) drugs. Because they do not kill healthy cells,they are capable of fighting cancer with fewer side effects such asnausea and hair loss.• One recent study found that inner-city children who had asthma, butwere enrolled in a comprehensive disease management program thatincluded appropriate medications, experienced significant quality oflife improvements. As their symptoms decreased and their capacity foractivity rose, they reported greater emotional well-being.24

39 Partners in care to Improve Quality of LifeYES WE ARE PARTNERS!!!Partners in care to Improve Quality of Life