Compared to patients with normal perfusion (<5% stress perfusion defect), the hazard ratio for an adverse cardiac event during a 4-yr follow-up period was 2.7 for patients with 5% to 10% perfusion defect; 3.3 for patients with 10% to 20% perfusion defect, and 4.1 for patients with a greater than 20% perfusion defect on regadenoson SPECT nuclear imaging. (J Nucl Cardiol. 2015 Feb 14.a)

Sunday, February 8, 2015

The PiB compound has been promising for detection of amyloid deposits in the brain. In this study of 22 patients,(11)C-PiB PET/CT was positive in 13 of the 15 with biopsy-proven cardiac amyloidosis, and negative in 0 out of the 7 patients without cardiac amyloidosis. (JACC Cardiovasc Imaging. 2015 Jan;8(1):50-9.)