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Rob Lowe joked that he turned down a part in "Grey's Anatomy" for a role in the short-lived series "Dr. Vegas."

They say there are some games that have no winners. This sounds like one of them.

"[Charlie Sheen and I] competed to see who could play harder, then show up for work and still kick ass,” admits Rob Lowe in a brand new "Vanity Fair" interview. "The verdict: Charlie by a nose."

No pun intended, we're sure.

Lowe, who has a recurring role on the hit comedy "Parks and Recreation," goes on to explain that there was a time when he and Sheen were considered "uncool" - mostly because they lived in Malibu but didn't surf. He describes Sheen as "a wonderful mix of nerd and rebel," before making it clear that the two future superstars had very different upbringings.

Over the course of the interview, Lowe also recounts his first meeting with Tom Cruise (“He’s open, friendly, funny, and has an almost robotic, bloodless focus and an intensity that I’ve never encountered before"), his many sexual conquests (including Demi Moore, Natassja Kinski, Princess Stephanie, and even Fawn Hall), and his feelings about being a member of the fabled Brat Pack that ruled movies during the '80s.

“We should all be so lucky in our lives to create things that we’re still talking about 25 years later.”