Tardive Dyskinesia/Dystonia, Parkinsonism & AkathisiaSSRI antidepressants induced side-effects (Iatrogenic
Extrapyramidal Symptoms) arerecognized to be similar to Neuroleptic (anti-psychotic) induced side-effects.
These side-effects are known as Tardive Dyskinesia/Dystonia (severe body movement disorder, mostly permanent),
Parkinsonism (a sign of future Parkinson's disease) and Akathisia (a Neurological driven severe mania/agitation that can lead to
suicidality, suicide attempts, self-harm & suicide).
It is well documented in the medical literature that these neuroleptic induced side-effects refer to damage at
dopaminergic neurons in the "motor system" of the
"Basal Ganglia",
a structure deep in the "Limbic System"
of the brain.
1,
2,
3,
4,
http://www.emedicine.com/EMERG/topic338.htm (scroll down)

Serotonin SyndromeThe Serotonin Syndrome
is a potentially lethal condition caused by excessive serotonergic activity.
It is a very dangerous and a potentially fatal side effect of the serotonergic enhancing drugs such as SSRI antidepressants
and is diagnosed by the presence of at least 3 of 10 symptoms: mental status changes (confusion, hypomania), agitation,
myoclonus, hyperreflexia, diaphoresis, shivering, tremor, diarrhea, incoordination, and fever.
This "hyperserotonergic" toxic condition requires heightened clinical awareness in order to prevent, recognize, and treat the condition promptly.
Promptness is vital because, as we just mentioned, the serotonin syndrome can be fatal and death from this side effect
can come very rapidly.
The Serotonin syndrome is brought on by excessive levels of serotonin and
is difficult to distinguish from the "Neuroleptic Malignant Syndrome" because the symptoms are so similar.
The "Neuroleptic Malignant Syndrome" is a serious condition brought on by the use of neuroleptic drugs (anti-psychotics).
Source: Prozac: Panacea or Pandora? by Dr Ann Blake Tracy
http://members.aol.com/atracyphd/syndrome.htmSource: Journal of Clinical Psychiatry

Antidepressant induced neurological and/or physical toxicity (body and/or brain damage) either as a result of prolonged inhibition of
P450-2D6 liver-enzymes, or as a result of impairing serotonin metabolism, can take on many forms as described below. A few examples are: Hyperserotonemia, such as the lifethreatening condition the Serotonin Syndrome,
Epileptiform Discharges, Epileptic Seizures and/or Epilepsy, Hypoglycaemia/Hyperglycemia
(Low/Elevated Blood Sugar Imbalance), Stroke/Hemorrhagic Syndromes, Frontal Lobe Syndrome, Tardive Dyskinesia/Dystonia, Parkinsonism, Akathisia, Mania, etc...