Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

All LSBio Custom kits have been predesigned and all necessary components, including antibodies and standards have been identified. Upon receiving a custom kit order, the kit will be assembled and quality control tested before being shipped out. Kit assembly and testing typically takes 4 to 6 weeks. In most cases the final kit is based on the Sandwich assay principle, with a few being Competitive EIA based. Specifications such as Range, Sensitivity, and Precision are defined upon completion. In the event that the custom kit cannot be successfully developed with 6 weeks of the order date, the customer will be notified and the order canceled at no cost.

Target:

IQGAP1

Reactivity:

Human

Description:

LS-F15971 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the detection of Human IQGAP1. It is based upon a Custom assay principle.

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Detection Range:

To be determined

Sensitivity:

To be determined

Kit Components:

Typical components include:

Coated 96-well Strip Plate

Standard (Lyophilized)

Sample Diluent

Assay Diluent A

Assay Diluent B

Detection Reagent A

Detection Reagent B

Wash Buffer (25x concentrate)

TMB Substrate

Stop Solution

Adhesive Plate Sealers

Storage:

Short term: 4°C; Long term: see manual.

Restrictions:

For research use only.

About IQGAP1

Description: Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.