Abstract

METHODS:Retrospective data review of 102 adults with confirmed PLCH, seen at our institution over 23 years.

RESULTS:Sixteen of 102 (16%) patients with PLCH, 12 men and 4 women, experienced 37 pneumothoraces, 10 patients (63%) had more than one, and in 11 (69%) was the initial presentation. Mean age at diagnosis was lower in the pneumothorax group (29.4 ±8.4 [mean±SD] vs. 42.3± 12.7; p<0.001). Recurrence was 58% (14/24 episodes) when pneumothorax was managed with observation or chest tube and 0% with surgery and pleurodesis. Survival was 13.8 years with pneumothorax and 18.3 without (p=0.715). Pulmonary function was not different in the pneumothorax group (p > 0.1).CONCLUSIONS: Recurrence was high when the pneumothorax was managed conservatively. No significant differences were observed in pulmonary function and survival in the pneumothorax group.

CLINICAL IMPLICATIONS:Our data supports the early use of surgical therapy with pleurodesis for pneumothorax in patients with PLCH.

Mode of Pneumothorax Management and Recurrences Rates in 16 Patients with PLCH

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