dear doctor Goodman
my mother was diagnosed ovarian cancer in june 2004: iv st g2; she got six cycles carbo-taxol for 4 times: every time disease come back every seven-eight months with raising of ca-125 and arise of liquid in pelvic region; last time doctors given her six cycles of carbo-caelyx and she stopped tre months ago. now ca 125 arise an ther'is liquid in pelvi another time. doctors said that now there is no drug that is better than another; what is the most effective drug in platinum resistant ovarian cancer and what i have to hope from its use.
thank you very much, Giovanni.

Dear Giovanni,
Thank you for your question. It sounds like it has been rough for your mother and I am sure it has been very tough for you as well. Your mother has received good drugs for ovarian cancer. If the cancer is returning within 6 months of therapy, we do label that cancer as platinum resistant.

There is no best chemo drug when a cancer is platinum resistant. Here is a list of options:
gemzar
topotecan
cytoxan
hexamethylmelamine
navelbine
taxol - in a different schedule such as weekly dosing
taxotere
tamoxifen
arimidex

We do just try one drug after another in this setting. The decision about which drug to use is usually based on side effects and how well a person is doing. There are also clinical trials of phase I and 2 drugs for women with platinum resistant cancer.

You should ask your mother's oncologist about these options.
best wishes

The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.