It dissolves best in water. Other liquids may contain ingredients which delay or affect dissolution. (For example, milk contains compounds such as protein and fat so it takes longer to dissolve the tablets.)

Room temperature is best. Cold water slows the dissolution, and warm water can make the product foam excessively. The surface of the tablet needs to be submerged completely in water for rapid dissolution.

The tablets may have started to break down. It's likely that the foil package has a slight imperfection or hole. This may cause the tablets to discolor and crumble. While there is no safety concern, be aware that the product won't be as effective.

We don't recommend using our products after they expire. It isn't harmful if ingested, but it may not be as effective in relieving your symptoms. We recommend you discard expired Alka-Seltzer Plus® products.

Liquid Gels: On the lower edge of the back carton, there are two down arrows. The flap lifts up to provide the remaining information, including the dosage directions. The information with the orange background (on the left) pertains to our Day Cold Formula, while the information with the green background (on the right) pertains to the Night Cold Formula. You can also view the directions online by visiting our product page.

Effervescent Tablets: The label on the back of the carton peels back, indicated by a yellow tab in the lower right corner. Once lifted, the remaining information and dosage directions are visible. The information with the orange background (on the left) pertains to our Day Cold Formula, while the information with the green background (on the right) pertains to the Night Cold Formula. View the directions online by visiting our product page.