Perceptual-Filling-In (PFI) and Motion-Induced-Blindness (MIB) are two phenomena of temporary blindness in which, after prolonged viewing, perceptually salient targets repeatedly disappear and reappear, amidst a field of distracters. We used monocular depth cues such as occlusion and those provided by the Water-Color Illusion and manipulated the eccentricity. Results show that the target disappears sooner and longer when it appears in back than when it appears in front. We argue that our earlier findings (Hsu, Yeh, & Kramer, 2004) that stereoscopically presented targets disappear longer when they have a negative rather than a positive or zero disparity reflect a more general effect of depth on PFI and MIB that is independent of how this depth is induced.