A command line tool for integrating functional genomic information into a genome-wide association study (GWAS). The basic setup is as follows: you have performed a GWAS or a meta-analysis of many GWAS, and have identified tens of loci that influence the disease or trait (our approach works best if there are at least ~20 independent loci with p-values less than 5e-8). We set out to address the following questions: (i) Are these associations enriched in particular types of regions of the genome (coding exons, DNAse hypersensitive sites, etc.)?, and (ii) Can we use these enrichments (if they exist) to identify novel loci influencing the trait?

Type:

Desktop

fgwas specifications

Unique identifier:

OMICS_11295

Interface:

Command line interface

Operating system:

Unix/Linux

Computer skills:

Advanced

Stability:

Stable

Maintained:

Yes

Software type:

Package/Module

Restrictions to use:

None

License:

GNU General Public License version 2.0

Version:

0.3.6

Requirements:

GNU Scientific, Boost

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