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Kuiper comes from a judo background and holds a black belt in the discipline.[2] He made his mixed martial arts debut in February 2009 and defeated his opponent, Ahmed Sultan, with a triangle choke. He went on to have a further six fights that same year, winning all of them in the first or second round. In 2009 he won the Belgium MMA title, and was rewarded with the MMA fighter of the year 2009.

Kuiper was expected to face Thiago Perpetuo on January 19, 2013 at UFC on FX 7.[6] However, Perpetuo suffered an injury and was replaced by Caio Magalhaes.[7] On December 27, it was announced that Magalhaes had also pulled out of the bout and that Kuiper would be shifted to UFC on Fox 6 on January 26, 2013 to face Buddy Roberts.[8] It was then announced on January 8 that Roberts had been forced out of the bout with an illness and was replaced by promotional newcomer Josh Janousek.[9] Then just days before the event, Janousek himself pulled out of the bout citing an injury. With no time to find a suitable replacement for Kuiper, he was pulled from the event as well.[10][11] This meant that 4 potential opponents for Kuiper (Perpetuo, Magalhaes, Roberts and Janousek) had all pulled out of the proposed bout.

Kuiper faced Brad Scott on October 26, 2013 at UFC Fight Night 30.[13] He lost the fight via front choke submission in the first round, and was subsequently released from the promotion shortly after.[14]