News and Resources from the Bessant Bioinformatics Lab at QMUL

Proteomics Informed by Transcriptomics

Proteomics Informed by Transcriptomics

In collaboration with David Matthews of the University of Bristol we have pioneered the use of de novo transcript assemblies from RNA-seq data for the routine creation of sample-specific proteomes. This approach, coined “Proteomics Informed by Transcriptomics” (PIT), brings the power of proteomics to previously intractable applications, such as host-pathogen studies and metaproteomics experiments.