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NANOMEDICINE

OVERVIEW

•Statistics

•What is nanomedicine ?

Applications

1)Tumors

2)Nanoinjectors

3)Surgery

4)Neuro-electronic interfaces

Ayman Ibrahim

2

STATISTICS

•

Nanomedicine is a large industry, with nanomedicinesales reaching6.8 billion dollarsin 2004, and withover200 companiesand38 productsworldwide, aminimum of3.8 billion dollarsin nanotechnology R&Dis being invested every year

•nanoinjectorbased on a single carbonnanotubethat isonly 25 nm in diameter.

•This canbe inserted into a singlecell.

•Thematerial is held in place by achemical linkagethatis sensitive to the cell interior.

•Oncethe tube is inside the cell, the linkage is brokenand thematerial is released.

•Thistechnique will be of great use to cell biologists,allowing themto overcomemany of the limitations ofexisting microinjection techniques.

Ayman Ibrahim

8

SURGERY

•At Rice University, a flesh welder is used tofuse two pieces of chicken meat into asingle piece.

•

The two pieces of chicken are placedtogether touching.

•

A greenish liquid containing gold-coatednanoshells is dribbled along the seam.

•

An infrared laser is traced along theseam, causing the two sides to weldtogether.

•solve the difficulties and blood leakscaused when the surgeon tries torestitch

the arteries and wounds.

Ayman Ibrahim

9

NEURO-ELECTRONIC INTERFACES

•Neuro-electronic interfacing is the construction ofnanodevices that will permit computers to be joinedand linked to the nervous system as to control anddetect nerve impulses .

Ayman Ibrahim

10

NEURO-ELECTRONIC INTERFACES

•The computers will be able to interpret, register,and respond (particpate)to signals the body givesoff when it feels sensations. The demand for suchstructures is huge because many diseases involvethe decay of the nervous system .

Ayman Ibrahim

11

NEURO-ELECTRONIC INTERFACES

•Also, many injuries and accidents may impair thenervous system resulting in dysfunctional systemsand paraplegia.

•If computers could control the nervous systemthroughneuro-electronic interface, problems thatimpair the system could be controlled so thateffects of diseases and injuries could be overcome.

Ayman Ibrahim

12

NEURO-ELECTRONIC INTERFACES

•It’s a sort of like a Remote for the bodywhere u could monitor body signals and alsosend signals to different body organs.

Ayman Ibrahim

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THANKS

Ayman Ibrahim

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REFERENCES

•American institute of physics

•Reviews in the journal Nanomedicine.

•

Brooks BR,Bruccoleri

RE,Olafson

BD, States DJ,Swaminathan

S,Karplus

M (1983). “CHARMM: A program for macromolecular energy,minimization, and dynamics calculations“. J CompChem

4: 187–217.

•

Brunger

et al. “Trypsinogen-Trypsin

Transition: A MolecularDynamics Study of Induced Conformational Change in the ActivationDomain”.