Asian catfish culture has been conducted in ABC Karawang to support aquaculture industrialization programs since 2010. Asian catfish can be cultivated in a high density and mass scale, but with low's margins. The selling price of this comodity is low and fish rearing is needs a long time. To increase the value added, in 2015 ABC Karawang perform asian catfish culture that used polyculture system with giants goramy which is a high economic fish. The objective of this activity is to produce fillet size of asian catfish > 700 g/fish as a profitable business with a gain of giants goramy as a byproduct. In the nursery phase is done in a 500 M2 ponds (stocked asian catfish 15,000 fish; giants goramy 3350 fish). In the growth phase is done 1000 m2 ponds (stocked asian catfish 10,000 fish; giants goramy 1000-2000 fish). Yields showed that the nursery phase obtained survival (SR) asian catfish 81-84%; giants goramy 56-75%. In the growth phase asian catfish 95-99%; giants goramy 47-57%. Feed conversion (FCR) in the nursery phase from 0.89 to 0.92%, while growth phase FCR 1.19 to 1.22. In the nursery phase can increase profits by 182%, while in the phase of enlargement could increase profits by 5.7%.