I like The Yog-sothoth cephalo-podcast. It is all about H.P.Lovecraft with a heavy emphasis of Role-playing Call of Cthulhu. They have several recordings of themselves playing Call of Cthulhu scenarios that are hilarious. check out Mask of Nyarlathotep and Horror on the Orient Express. It takes-up alot of time. I also like Penny-arcade's podcast: Downloadable Content, a daily online comic, the less reliable podcast is basically a recording of them coming-up with the comic idea for that day. Comic book readers will love Fan Boy Radio which is actually a podcast of an hour-long radio show. They've had great comic book writers and artists on as well as some cool actors and music artists. I enjoyed the interview with Wil Wheaton. The World War Z podcast has some excerpts from the book. It is basically a promotion for the audio book though. There is a Frankenstein podcast which is the entire book on audio, that'll be some fun listening. And If you like listening to people talk about the video game industry you'll love the Game Theory Podcast. Those are most of the ones I listen to and none of them are music.

CBC Radio has two podcasts I listen to: Dispatches, with a variety of submissions from journalists around the globe, and Ideas: "programs that explore everything from culture and the arts to science and technology to social issues".

I already approve of many things already mentioned: pseudopod and Escape pod, as well as This American Life. Anything you can find featuring Mur Lafferty reading her work is also worthwhile. In addition to stuff already mentioned, she has an ongoing fantasy/magical realism series called Heaven (season 2 is called Hell, and so on...) dealing with adventures in the afterlife that's pretty nice. Her stuff is delightfully fun, and she's a great reader/narrator.

To that, I add Dan Savage's Savage Lovecast. If you've ever read his print column, just imagine that with him fielding recorded questions from listeners, often calling them and interacting with them in the podcast.

My hero The Amazing Randi has a podcast, but I've only listened to one episode so far, so I can't vouch for it yet. Though I have high hopes.

Last: though I have yet to read his fiction, I've found a bunch of stuff by SF author Rudy Rucker (find him on itunes podcast search), some fiction reading, some lectures that are all fascinating.

I'm addicted to podcasts, video and audio. I'm subscribed to too many to list here, but her's a few of my favorites...

Alive in BaghdadThis weekly video podcast is put together by Iraqi journalists on the ground and involves a variety of topics, from corruption in the passports bureuas to the efforts to clean up a soccer field in Basra. It attempts to show life in Iraq through the eyes of the people who have to live and work there. It is informative and eye opening, and if you have any interest in what's going on in Iraq, I recommend it.

Ask a NinjaStupid and hillarious is about all I can say. May not be to your taste, but I like the Stoopid Funny.

The Best of the LeftThis is a weekly podcast that aggregates clips from across the left-wing media spectrum, from Keith Olberman to the Young Turks. It's a good way to pick up on anything you might miss from the real "liberal media" on a weekly basis.

CrackleI get several video podcast from here, including "Penn Says" which is just Penn Jillete talking shit for several minutes every other day or so, there's also a short film podcast, a sketch comedy podcast, and several others. Good stuff.

Tiki Bar TVThis seems to come out at random, and is more dumb fun. Also includes a drink recipe with every episode.

Aliens You Will Meet This is a cute, short podcast that comes out weekly. It deals with the adventures of an interplanetary Ambassador as he meets different aliens. There was a puppet show of this podcast at DragonCon.

Voices: New Media Fiction This is the first ever podiobook anthology. It was edited by Mur Lafferty, who I see has some fans here.

I'd like to throw my two cents in for This American Life and Savage Love as well. Both are great podcasts.

This Is HellFrom Chicago/WNUR. Each week, four hours of uninterrupted interviews with all the relevant left-ish thinkers. Comedic relieve interspersed as necessary. Better than Democracy Now! - but I am biased as I contribute to the show. Still, highly recommended. Take a look at who they have had on in the archives and you'll know right away if it is of interest to you.

My associate Jesse Munoz and myself record a podcast called Sidetracked twice a week concerning movies, comics, and whatever other topics strike our fancy. You can find the show at Sidetracked The Podcast.