Parkinson's Disease Support Group

Parkinson's disease is a movement disorder often characterized by muscle rigidity, tremor, a slowing of physical movement, and in extreme cases, a loss of physical movement. The primary symptoms of Parkinsons are due to excessive muscle contraction, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the...

concern's of doctors

Minutes of the Recombinant DNA Advisory Committee 9/20/06
efficacy, potential participants may flock to the Phase II trial and, therefore, some formal rate of enrollment should be established.
Dr. Piantadosi requested that the investigators give additional serious consideration to unmasking the monitoring committee.
Dr. Kirchhoff expressed concern about the long list of exclusion criteria. To the extent that the exclusion system is stringent, it creates a numerically small subgroup in the larger group of PD patients. The risk is that that subgroup may not be representative of the general PD patient population, and the long-term risk, if this approach is successful, is that the positive findings will be applied to the larger group.
To help determine the risks for the sham surgery participants, Dr.

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