The chapters in this book reflect the range of technical advances and their applications that are currently transforming biology. Topics covered include the application of computational methods, the robotics of modern automation methodologies, the new chemical and imaging methods that reveal chromosome structure and elucidate gene function, and the emergence of evolutionary and functional information by comparative genomics. Eminent international scientists describe in detail the new technology necessary to study the entire genome in a holistic manner and all the high throughput and large-scale experimental methodologies currently being used in genomic science. In addition the authors describe the progress of the newest technologies that are currently being developed. Written by experts in the field, this concise yet informative volume covers all aspects of technology pertaining to genomic studies. An essential book for anyone involved in genomic science.

"This book provides a very comprehensive review on numerous comtemporary genomics technologies and tools by a team of experts in the field. Very informative for getting a quick comparison of different technologies!"fromFunctional Genomics.

"The chapters in this book reflect the range of technical advances that have, and are presently, transforming the way we perform genomic analyses in the lab ... Topics covered in this book are generally well covered and clearly explained, plus each chapter contains a helpful further reading section. This book ... would be of general interest to anyone working within the genomic technology field."fromMicrobiology Today (2003) 30: 48.

"On balance, I liked this book. ... if you're looking for twelve diverse and generally well-written reviews bound into one volume, this will do nicely."fromHuman Genetics (2003) 113: 193.

"... this volume provides useful information about both current and emerging genomic technologies ... this is a good quality production; the presentation of the text is easy to the eye, broken up by a sufficient number of illustrations. A useful introduction to genomic technologies for anyone from graduate students to researchers."fromThe Biochemist (2003).

"The Functional Genomics Series describes the state-of-the-art of technical means to efficiently analyse sequence information - provided by the nascent disciplines of bioinformatics and computational biology - and the need to fit the genomic pieces into the puzzle of biological function, resulting in an understanding of the functioning of complex systems of genes and macromolecules."fromInternational Microbiology (2003) 6: 75-78.

" ... describes in detail the new technologies available for studying the whole-genomes of organisms ranging from microbes to humans."fromInternational Microbiology (2003) 6: 75-78.

Table of contents

1. An Historical Perspective on Genomic Technologies

David J. Galas and Stephen J. McCormack

2. Molecular Cytogenetics and Human Genome Function

Pierre P. Massion and Joe W. Gray

3. Genome Comparison Techniques

Lisa Stubbs

4. Impact of Transgenic Technologies on Functional Genomics

Cooduvalli S. Shashikant and Frank H. Ruddle

5. Present and Future Tags and Labels in High Throughput Genomic Analysis