High Throughput Genomics (HTG)

The High Throughput Genomics group of Prof. Dr. Annalisa Marsico, jointly established by the FU Berlin (FB Mathematics and Computer Science) and the MPI for Molecular Genetics, focuses on the bioinformatics of non-coding RNAs in both eukaryotes and bacteria and their predicted role in gene regulatory networks.

Besides the implementation of pipelines to analyze and integrate several types of novel high-throughput genomic data (small RNA-seq, i-CLIP and Hi-C data), the research aims at building coherent stastical models to explain the data and ultimetely help deriving mechanistic biological hypothesis about non-coding RNA function and regulation.Close collaboration with experimental groups inside and outside FU in order to validate the in silico predictions with wet lab experiments is part of the research.