]]>http://cannabissativaphd.com/new-jersey-city-list/feed/0126How to Get into the Marijuana Industryhttp://cannabissativaphd.com/get-marijuana-industry/
http://cannabissativaphd.com/get-marijuana-industry/#respondTue, 03 Oct 2017 02:15:34 +0000http://cannabissativaphd.com/?p=103How to Get into the Marijuana Industry

The Growing Marijuana Industry

The marijuana industry is highly regulated and starting a new business can, therefore, require a lot of time and money to become approved as a state-approved medical marijuana business. Read on to learn about how to get into the weed business and the different types of business roles available within the marijuana industry.

To get into the cannabis business in any state, you must first work with either the State Department of Health, Department of Commerce, and/or Department of Taxation to become a licensed medical marijuana business. This process is easier in some states with more lenient marijuana laws, such as California, where recreational use of marijuana is also legal. In other states, it may be difficult to get involved in the industry. For example, if your state only operates state-owned dispensaries, it can be more difficult to get into the weed business. If your state has legalized recreational marijuana use, there would be many more opportunities for you to open a business selling marijuana-containing products.

In a few states where medical marijuana is not legal, it is still possible to open a business selling derivatives of marijuana and hemp, such as cannabidiol (CBD) oil. However, this may be a bit of a gamble, as the Drug Enforcement Administration views CBD oil, and virtually all other marijuana-based products, as illegal.

In states with legal medical marijuana, individuals wishing to get into the marijuana business can apply with their state to establish cultivation centers, dispensaries, and in some states, sell marijuana-based products. For those who have the proper credentials, such as medical professionals, a host of medical opportunities are available as well. The availability of these types of business opportunities varies by state; for example, if you live in a state where recreational marijuana is illegal, it would therefore also be illegal for you to open a marijuana-infused baked goods company.

There are several facets of the medical marijuana business that, depending on your state, it may be possible to operate within. Marijuana businesses are largely limited to operating within one state, due to the complex laws regulating marijuana possession and use that could prohibit the trafficking and transport of marijuana across state lines, even if the states in question have legalized medical and/or recreational marijuana.

How to get into the Marijuana Industry as Marijuana Growers?

To become a marijuana grower, it would be helpful to have several years of experience running a commercial-scale garden. You must also familiarize yourself with the basics of cannabis horticulture, such as the different phases of plant growth, plant watering and ventilation, plant nutrition, and plant harvesting; you should also familiarize yourself with how to identify pests and how to properly use (or avoid the use of) pesticides. You should know that most marijuana growers are on call around-the-clock, so if something goes wrong at the cultivation center, you will be required to travel to the center to fix it at any time of the day.

If you do not think that you are ready to work in or operate a cultivation center, you may consider applying to be a trimmer. A skilled trimmer is required to remove the unwanted materials of the marijuana plant during harvest.

It may or may not be possible to open your own cultivation center in your state. Consult your local state’s medical marijuana laws to determine what is and is not possible. Some states operate entirely state-owned cultivation centers, while other states that have legalized recreational use of marijuana have a less strict process for opening a cultivation center.

How to get into the Marijuana Industry as a Marijuana Dispensaries?

Like marijuana cultivation, the operation of marijuana dispensaries varies by state – some states’ dispensaries are highly state-controlled, while other states allow private citizens to open cultivation centers and dispensaries. Running a marijuana dispensary can bring a salary of $100,000 or more, according to Robert Calkin, CEO of the Cannabis Career Institute. States have different laws about how much marijuana citizens can possess for medical use – some states allow 1 ounce of marijuana at any time, while other states allow the possession of up to 24 ounces of weed. If you decide to open your own dispensary

Some states also allow individual citizens to grow marijuana plants in their home – consult your state laws to find out exactly what is and is not legal in your state. However, in most states, it remains illegal to sell any marijuana, including home-cultivated marijuana, to another person.

Selling Marijuana-based products

In general, unless a state has legalized recreational marijuana, it is not possible to sell marijuana-based products. One exception is CBD oil, which has been legalized in some states that have not legalized medical marijuana. To open a marijuana-based business, you may need to register with the medical marijuana registry of a given state and follow the laws relating to marijuana set forth by the state’s Department of Commerce and Taxation.

Will CBD Oil show up on Drug Tests?

Although cannabidiol (CBD) is an inactive compound with no psychoactive effects, it is possible that using cannabis-derived CBD oils and other CBD products could theoretically lead to a positive drug test. CBD oil can also be made from hemp, in which case, (Check them out on Amazon) hemp-derived CBD products are legal in any state, can be purchased over-the-counter, and do not require a medical marijuana prescription or other special authorization from the state.

Most cannabis-based CBD products are in the form of oil-based capsules or extracts either taken orally as a supplement or used topically as a lotion. However, new CBD products are constantly arriving on the market.

The United States Food and Drug Administration (FDA) has repeatedly warned companies who manufacture CBD oil to improve incorrect labeling. CBD oil manufacturers have also been criticized by FDA for making medical claims that remain unsubstantiated by the scientific literature. Therefore, it can be difficult to have complete confidence that the CBD oil being sold on the medical marijuana market is in fact what it claims to be. Therefore, individuals who are concerned about having positive drug tests while using CBD oil may want to consider transitioning to a hemp-based CBD oil or taking regular drug tests on their own, because it can be impossible to know what the true component profile of cannabis-based CBD oils are.

What are some different types of drug tests that screen for compounds found in marijuana and other drugs?

There are many types of drug tests that enable detection of compounds in blood, urine, hair follicles, and even perspiration. These different tests can test directly for the drugs of interest, metabolites, and other indirect or direct markers, and have various levels of sensitivity and specificity. However, certain vitamins and minerals, as well as a few prescription and over-the-counter medications can interfere with various types of drug tests and either mask positive results or cause false positives. Therefore, the gold standard, in drug testing is the application of an analytic chemistry technique, Gas Chromatography-Mass Spectrometry (GCMS), to test samples to enable the identification of compounds with very high accuracy.

How do drug tests for marijuana work?

There are many different ways to test for marijuana, which is easy to detect by urine, hair, or saliva tests. Cannabinoids are fat-soluble and can be stored in the body’s fat cells, and therefore will be detected on one’s body and in one’s system for days or even weeks after use. The concentrations of marijuana detected by urinalysis, hair follicle analysis, or saliva tests can distinguish between a person who has been actively smoking or consuming marijuana and a person who has spent some time in the same place as a marijuana smoker.

Can CBD oil show up on a drug tests?

Hemp-based CBD oilcan show up on drug tests, especially in cases where a very large amount of the hemp-based product has been used (e.g., consumed or applied topically). However, gas chromatography-mass spectrometry (GC-MS), a more expensive analytic method, can distinguish between using hemp-based products such as hemp-based CBD oil, which is not illegal, and cannabis, which is a Schedule I Controlled Substance according to the Drug Enforcement Administration. In a study by Fortner and colleagues (1997), participants screened positive for marijuana after eating a hempseed bar, but GC-MS did not give a detectable level of marijuana in their systems.

It is important to note that CBD oils are derived from flowers, leaves, and stalks of the marijuana or hemp plant. Therefore, cannabis-derived CBD oil is indeed derived from marijuana and could lead to a positive result on a drug test due to the trace presence of THC in the cannabis-derived product. This positive finding would likely be substantiated by GC-MS.

When and for how long does CBD oil show up on drug tests?

This depends, but marijuana is slow to leave the body and unlike alcohol, which is partially water-soluble, marijuana is fat-soluble and therefore not immediately excreted. Hemp-based CBD oil should not contain some of the psychoactive chemicals present in marijuana and should ultimately be able to be confirmed as a false positive by GC-MS. However, cannabis-based CBD oil could contain trace amounts of marijuana, and if that is indeed the case, the GC-MS test would remain positive for days or weeks.

Marijuana can be stored in fat cells for a long time. People with a high body fat percentage could potentially store the compounds present in marijuana in their adipose tissue for a longer time than individuals with a lower amount of body fat.

Cannabis is a scientific term that refers to the taxonomic name of the plant that produces both marijuana and hemp. Specifically, cannabis is the genus of the plant Cannabis sativa. There are three main species, or varieties, of cannabis: cannabis sativa, cannabis indica, and cannabis ruderalis. Cannabis sativa is most often cited as the plant from which both marijuana and hemp originate.

In 1970, the Controlled Substances Act classified all forms of cannabis – including hemp – as a Schedule I drug, making it illegal to grow marijuana or hemp in the United States. While the federal government considers marijuana to be an illegal schedule I controlled substance, the federal government has relaxed some regulations on hemp, due to its lack of psychoactive properties, which has made cultivating and manufacturing hemp much easier and widespread. For this reason, hemp is readily available in stores like Amazonand is added to a variety of products available on the market. Marijuana remains tightly regulated and only is legal to use in certain states.

What is Hemp?

Hemp was first cultivated in what has now known as Taiwan over 10,000 years ago. Hemp was used in textiles as long ago as 4000 BC.

Legally, hemp can be defined as a cannabis plant that has very low THC and high CBD. Hemp and marijuana, therefore, are different varieties of the same plant. Hemp has been used for centuries to create fuel, paper, food, textiles, detergents, plastics, paints, and varnishes. Hemp contains about 0.3% to 1% THC. Hemp cannot be grown in the United States without a permit from the Drug Enforcement Administration (DEA). Despite the federal prohibition, 32 states have legal means to grow industrial hemp, seven states allow the cultivation of hemp crops for research, and five states allow registered farming of hemp.

Marijuana

Just like hemp, marijuana has a storied history of use. The first recorded historical use of marijuana was by a Chinese emperor in 2727 BC, and cannabis seeds were used in food in Ancient China as long ago as 6000 BC.

Marijuana refers to the cultivation of the cannabis plant for recreational or medicinal drug use. Marijuana contains up to 25% THC. The federal government, including the DEA, recognizes marijuana as an illegal drug, but several states have approved the use of recreational and medicinal marijuana through state-run registries and industries.

Hemp versus Marijuana – How are hemp and marijuana similar?

Marijuana and hemp are derived from the same family of plants, but what differentiates hemp from marijuana is the level of the psychoactive compound delta-9-tetrohydrocannabinol (THC) that marijuana contains. Other cannabinoid compounds, such as CBD, can be present in both marijuana and hemp. Marijuana has a much higher concentration of THC than hemp does. Marijuana is approximately 25% THC, whereas hemp has a trace amount of THC. THC is responsible for marijuana’s psychoactive effects. The psychoactivity of marijuana is largely the reason that it has been classified as an illegal drug.

In what part of the cannabis plant are hemp and marijuana located?

Marijuana, as it is used recreationally or medicinally, typically refers to smoking of the flowers formed after a cannabis plant sprouts. Hemp, on the other hand, can include the entire plant, including the stalks and plant fibers, which are often used in paper products.

Hemp protein bars are a delicious and convenient source of vegan protein. Vega is a protein supplement company that sells many delicious flavors of protein bars containing hemp seeds. Protein bars are available in chocolate peanut butter, coconut cashew, chocolate caramel, and other healthy and delectable flavors.

What is Cannabidiol/ CBD Oil?

Cannabidiol oil, also called CBD oil, is a compound that can be made from the cannabis sativa plant or its non-psychoactive relative, the hemp plant. In cannabis, cannabidiol (CBD) is one of hundreds of active compounds, and CBD in particular makes up a significant portion of the content of the cannabis plant, comprising up to 40% of the plant’s extract. CBD oils are derived from flowers, leaves, and stalks of the marijuana or hemp plant. Unlike marijuana, CBD does not have psychoactive effects.

The US Drug Enforcement Administration has classified marijuana as a Schedule I controlled substance, which means that it is against federal law to possess or use marijuana in any form, including as CBD. Therefore, the use of CBD oil is also not approved by the Food and Drug Administration (FDA), and many of the health claims have not been rigorously evaluated. However, the use of medical marijuana is legal in many states, and in some states which have not legalized medical marijuana, the use of products containing CBD has also been legalized.

What uses does CBD Oil have?

The health claims made by sellers of CBD oils have not been thoroughly evaluated by the FDA. However, scientific research studies have established potential therapeutic roles for CBD oil for many conditions, including cigarette addiction, acne, diabetes, fibromyalgia, Post-Traumatic Stress Disorder (PTSD), schizophrenia, Crohn’s disease, multiple sclerosis, and insomnia. These potential treatments may stem from the interactions of the cannabinoid with endocannabinoid receptors in the brain, organs, and immune system. CBD is known to have anti-epileptic, anti-depressant, anti-inflammatory, anti-nausea, antioxidant, muscle relaxant, and sedative properties.

In some cases, CBD can be used as a treatment for patients, especially children, with epilepsy that does not improve by the use of seizure medications — approximately 33% of all patients. However, according to a report conducted by the National Academy of Sciences, more research must be done to elucidate whether CBD or marijuana can be used as an effective epilepsy treatment.

According to the American Cancer Society, in-vitro laboratory studies have shown that cannabinoids such as CBD have been shown to slow the growth of or cause the death of cancer cells. These cannabinoids may also reduce the growth of some forms of cancer. However, further study is required to better understand the effect of cannabinoids on cancer cells in the human body; using marijuana or CBD by itself as a form of cancer treatment can have harmful health consequences.

Different Types of CBD Oil: Top 10 Products from Amazon

Cannabidiol, or CBD, oil cannot be purchased online because of marijuana’s designation as a Schedule I controlled substance and illegal drug by the federal government. However, many hemp oils are available on the market. Hemp seed oil is made from the seeds of the hemp plant, which are cold-pressed to create a delicious oil that is high in healthy unsaturated fats including Omega 3 and Omega 6. No cannabinoids are present in hemp seed oil.

Hemp oil is legal in most countries and can be found at the grocery store in the oil section. It is also used as an ingredient in many lotions and soaps. Hemp oil can also be found in eco-friendly plastics and paints.

]]>http://cannabissativaphd.com/what-is-cannabidiol-cbd-oil/feed/087How to get into the Marijuana Industry by statehttp://cannabissativaphd.com/how-to-get-into-the-marijuana-industry/
http://cannabissativaphd.com/how-to-get-into-the-marijuana-industry/#respondWed, 06 Sep 2017 20:02:48 +0000http://cannabissativaphd.com/?p=74How to get into the marijuana industry: by state?

If you want to know how to get into the marijuana industry, you"ve come to the right place. Read on to find out how to qualify as a medical marijuana business and as a user in each state. In all 29 states and the District of Columbia where medical marijuana has been legalized, the use of medical marijuana requires a form, prescription, or another type of written statement from the patient’s physician. These qualifications are always evolving, but we want this page to be a resource of information by state on how to get into the medical marijuana industry by state.

California Qualifications of Medical Marijuana

To start a cannabis business in California, you must register with CA’s Bureau of Medical Cannabis. Individuals wishing to use medical marijuana must have a qualifying physician’s recommendation or a valid county-issued medical marijuana identification card. More information is available from the California Department of Public Health.

How to get into weed business in Colorado?

People wishing to start a medical marijuana business in Colorado must file an application with the Marijuana Enforcement Division. Individuals wishing to join the medical marijuana registry in CO can do so by visiting the Colorado Department of Public Health and Environment’s Medical Marijuana Registry website.

Connecticut Medical Marijuana Qualifications

To use medical marijuana in CT, individuals must obtain a Connecticut medical marijuana certificate from the Connecticut Department of Consumer Protection. To open a medical marijuana business in Connecticut, individuals must apply with the Department of Consumer Protection as well.

Delaware Medical Marijuana Qualifications

Full details are not yet available, but qualified patients wishing to use medical marijuana in DE must register with the Delaware Department of Health. Delaware currently has one medical marijuana distribution center and is working to create up to two more centers. Applicants can learn more about how to open a medical marijuana dispensary center here.

Florida Cannabis Qualifications

Qualified patients must join the FL Medical Marijuana Use Registry. Floridians cannot grow their own marijuana but it is legal to apply to open a Medical Marijuana Treatment center under Florida law. Consult the FAQs at the FL Department of Health for more information.

Illinois Medical Weed/Cannabis Qualifications

Illinois Department of Public Health oversees a Medical Cannabis Patient Registry Program. Patients wishing to learn more about the program can do so at the IDPH website. Applicants wishing to open a medical marijuana cultivation center must submit an application with the Illinois Department of Agriculture and those wishing to open a business can file here thanks to the Compassionate Use of Medical Cannabis Pilot Program Act.

Maine Medical Marijuana Regulations

Maine Medical Use of Marijuana Program information is located at the Department of Health and Human Services of Maine here. Registration with the Maine Medical Marijuana Program is mandatory for those wishing to start a business but optional for patients seeking a prescription, who must simply possess a medical marijuana registry ID card issued by the Maine Department of Health and Human Services.

Maryland Medical Cannabis Pending

The Maryland Medical Cannabis Commission (MMCC) oversees marijuana-related laws and access for businesses and patients in MD. Medical cannabis is currently not available in the state of Maryland, but the MMCC expects availability by the end of summer 2017.

Massachusetts Medical Marijuana Laws

Marijuana use by patients and medical marijuana businesses are regulated by the Medical Use of Marijuana Program of the Department of Health and Human Services of MA. Patients must register to enter the medical marijuana program and to open a medical marijuana dispensary.

Michigan Michigans Medical Marijuana Program

Information on Michigan’s Medical Marijuana Program for patients and businesses can be found here.

Minnesota Medical Marijuana Information

Consult the website of the Minnesota Department of Health for information on medical cannabis for patients and businesses here.

Montana Medical Cannabis Information

The Montana Medical Marijuana Program oversees the distribution of medical marijuana to patients and by businesses; more information is available here.

Nevada Cannabis Industry

Licensed retail marijuana stores must register with Nevada’s Department of Taxation. Individuals seeking medical marijuana prescriptions can find out more about the requirements here.

New Hampshire Medical Weed/Marijuana program

While no current regulations exist for marijuana businesses in the state of NH, patients seeking medical marijuana must register with the Therapeutic Cannabis Program. More information is available here.

New Jersey Medical Cannabis Program

The State of New Jersey’s Department of Health oversees the Medical Marijuana Program for businesses and patients; more information is here.

New Mexico Medical Cannabis Program

New Mexico patients of medical marijuana must obtain an ID card to participate in the registry. Businesses must obtain certification from the New Mexico Department of Health. Information about New Mexico’s Medical Cannabis program, for patients and businesses, is here.

New York: How to get into the marijuana industry

Medical marijuana patients must register online and obtain a registry ID card to participate in the registry. Medical marijuana businesses should apply to the New York State Medical Marijuana Program. Information about New York State’s Medical Marijuana Program is located here.

North Dakota: How to get into the marijuana industry

North Dakota’s Department of Health oversees the state’s medical-marijuana program. More information for patients and those wishing to open a business is located here.

Ohio: How to get into the marijuana industry

The Ohio Medical Marijuana Control Program will allow people with certain medical conditions to buy and use medical marijuana. More information for patients is here.

Oregon: How to get into the marijuana industry

The Oregon Medical Marijuana Program oversees the cardholder registry for patients prescribed medical marijuana. Medical marijuana information for patients, growers, processors, dispensaries, physicians, and laboratories is available here. Learn more about dispensary and cultivation rules here.

Pennsylvania: How to get into the marijuana industry

Pennsylvania residents The Pennsylvania Medical Marijuana Program oversees the medical marijuana operations of the state; a medical marijuana ID card is required to obtain medical marijuana. More information for patients and businesses can be found here.

Rhode Island: How to get into the marijuana industry

The RI Department of Health’s Medical Marijuana Program administers the state’s Medical Marijuana Act provisions and its related laws. More information about the Medical Marijuana Program is located here.

Vermont

Patients and dispensaries must register with the Vermont Marijuana Registry; more information is here.

Washington

The Washington State Department of Health has listed the requirements for becoming a medical marijuana patient here. A patient must first get a medical marijuana authorization and then join the database and get a medical marijuana card. Click here to learn more about how set up a medical marijuana retail store in the state of Washington.

West Virginia

The WV Bureau for Public Health is in the early stages of developing West Virginia’s medical marijuana program, which is not yet functional; however, full details about the program are here.

Why do we have cannabinoid receptors?

What are receptors and how do they work in the body?

To understand why do we have cannabinoid receptors we must first understand what receptors are. Receptors are proteins typically found on a cell’s surface which bind to compounds called “ligands.” Ligands can be a neurotransmitter, hormone, or other substance which bind to a receptor. Brain cells, which are also called neurons, have many different types of neurotransmitter receptors. The receptor system that binds cannabinoids that come from marijuana use or from endogenous cannabinoids produced within the body is called the endocannabinoid system.

A ligand-receptor interaction can activate many diverse downstream responses. In the brain, the interaction of a receptor with a neurotransmitter can cause a cascade of molecular interactions, ultimately controlling and directing a vast array of cognitive and behavioral responses such as learning, memory, motor control, and decision-making.

Cannabinoids can have many diverse effects in the body, both from their direct interactions with cannabinoid receptors and the interactions that can occur downstream of these interactions, which affects the release of other neurotransmitters.

While cannabis is a frequently abused drug when used for recreational purposes, medicines including cannabinoids can potentially serve many therapeutic purposes, including the treatment of nausea and vomiting, eating disorders, cancers, and neurodegenerative conditions, due to the complex dynamics of the cannabinoid system and the widespread localization of different types of cannabinoid receptors throughout the body.

Visualization of endocannabinoid Signaling System

What are cannabinoid receptors?

Cannabinoid receptors are a category of receptors located on the cell membrane of cells throughout the body and are involved in various physiological responses including appetite, the sensation and perception of pain, mood, and memory. Cannabinoid receptors also play an important role in immune system modulation, this answers the question of why do we have cannabinoid receptors in the body.

What are the different types of cannabinoid receptors and what do they do?

Two types of receptors have been identified in the endocannabinoid system and are located throughout the brain, organs, and immune system. These receptors are called CB1 and CB2. Most cannabinoids can bind to both the CB1 and CB2 receptors in the body. In the brain, CB1 can be found on neurons in regions including the basal ganglia, cerebellum, hippocampus, and cerebral cortex. CB2 is primarily found in the immune system.

When C1 receptors are activated by a ligand — such as THC or anandamide — these receptors can modulate the release of many neurotransmitters including acetylcholine, norepinephrine, dopamine, serotonin, glutamate, and GABA. Unlike most neurotransmitter receptors, CB1 cannabinoid receptors in the brain can bind ligands presynaptically; most other neurotransmitters act postsynaptically (after an action potential has fired). In this way, cannabinoid receptors can have a more modulatory effect on brain function than “traditional” neurotransmitters. The actions of CB1 receptors in the brain can be considered to have a function that is similar to a “dimmer” function on a light switch. Compared to rats, humans have relatively high concentrations of CB1 receptors in the cerebral cortex, which is involved in higher-level reasoning and decision-making, and the amygdala, an important node for fear, anxiety, and emotional processing. CB1 receptors are activated by various compounds including the chemicals anandamide and 2-arachidonoylglycerol (2-AG) that are naturally produced in the body, as well as plant cannabinoids such as the psychoactive compound THC which is found in cannabis.

CB1 plays a role in drug-seeking behavior; several studies now indicate that activating the CB1 receptor in addicts restores drug-seeking behavior, likely due to the presence of CB1 receptors in the brain’s limbic system, and particularly due to the interaction between these receptors and the dopamine receptors in the nucleus accumbens. CB1 receptors act as an upstream modulator of dopamine neurons, and CB1 receptor antagonists can reduce drug-seeking behavior in some addicts.

CB2 cannabinoid receptors, which were discovered in 1993, are mostly located in the immune system. CB2 receptors have been found on T cells in the body’s immune system and therefore may have a host of largely unexplored therapeutic applications. 2-AG, which is produced in the body naturally, is the primary ligand for 2-AG, but plant-based cannabinoids also bind to and affect the functioning of CB2 receptors.

What are CB1 and CB2 Receptors?

How does the endogenous cannabinoid, or endocannabinoid, system work? What effects do cannabinoid receptors control in the body?

The endocannabinoid receptor system has two main receptor types, and most cannabinoids and endocannabinoids bind to both types.

The endocannabinoid system works in two main ways – it can be activated by the production of cannabinoids made by the body or those taken from a plant-based or other sources, such as marijuana or synthetic analogs.

The body produces endogenous cannabinoids, or endocannabinoids, such as anandamide. Anandamide is an endocannabinoid which is synthesized in the Purkinje cells of the brain and can inhibit the release of glutamate or GABA in the neocortex. Unlike most neurotransmitters, cannabinoids act on the presynaptic neuron – other neurotransmitters, such as acetylcholine or dopamine, act postsynaptically (after a neuron has fired). The other way that the endocannabinoid system can be stimulated is by the use of marijuana and similar compounds which contain THC, a compound which interacts with receptors of the cannabinoid system. THC has a chemical structure that is very similar to that of the endogenous compound anandamide and therefore can bind at the same receptor sites.

The endocannabinoid system is also stimulated when individuals take marijuana or synthetic marijuana analogs, which can stimulate the cannabinoid system. Delta-9-tetrahydrocannabinol, or THC, is an active ingredient in marijuana that gives users a “high” feeling. THC acts on the brain’s endocannabinoid system, interfering with the brain’s natural ability to create and use endocannabinoids that the body makes, e.g., the production of the endocannabinoid anandamide after a hard workout. THC gives a marijuana user a feeling of euphoria due to its interactions with the endocannabinoid system. While these effects may be pleasant or rewarding in the short term, chronic marijuana abuse can heighten the release of dopamine and dysregulate the brain’s reward system with chronic abuse. THC can also act on the brain to dysregulate the natural balance of neurotransmitters, causing behavioral manifestations such as anxiety. People who abuse marijuana or THC can, therefore, experience a vast array of psychological and cognitive symptoms such as hallucinations, delusions, and a loss of the sense of personal identity.

Thanks to CB2 receptors, cannabis also plays a role in the modulation of the body’s immune system, and play a role in cytokine release, which is part of the body’s normal immune response. While it was previously thought that CB2 receptors were solely localized to the immune system, recent studies indicate that CB2 receptors may also be located on brain cells as well, leading to a complex neuro immune interaction in this receptor system which could potentially be a novel therapeutic target.

We hope this information has helped you answer the question: why do we have cannabinoid receptors to begin with.

What are Purkinje cells?

Purkinje cells, which are also called Purkinje neurons, were the first neurons identified in the brain. Purkinje cells are neurons (brain cells) located in the brain’s cerebellar cortex. Jan Evangelista Purkyně was the first to discover these cells in sheep brains in 1832. Santiago Ramón y Cajal, who drew detailed maps of neurons in the late 1800s, was awarded the Nobel Prize in Physiology or Medicine in 1906 for his drawings of neurons including Purkinje cells.

To understand the function of Purkinje cells, it is important to know about basic neuronal structure. Each neuron in the brain has a cell body, or soma, from which many spinelike processes, called dendrites, originate. Dendrites serve to collect input from nearby firing cells. Each neuron also has an axon, which is an insulated fiber that conducts action potentials to signal to nearby cells.

Structurally, Purkinje cells are very distinct, and were famously drawn by Ramón y Cajal in 1899. Each Purkinje cell has many dendrites, or branches, which receive inputs from other neurons that are called granule cells. Each Purkinje cell also has an axon, which is a single projection that transmits signals to the cerebellum, which controls movement and cognition. Purkinje cells are inhibitory, so their activity reduces the activity of adjoining brain cells. Purkinje cells dampen the activity of adjoining neurons by releasing GABA, an inhibitory neurotransmitter which binds to receptors and acts to decrease neuronal activity. Purkinje cells also engage in retrograde signaling, which refers to the backwards transmission of neurotransmitter molecules. Retrograde signaling of Purkinje cells serves as a key modulatory function for these cells.

Where are Purkinje cells in the brain?

Purkinje cells are located in the brain’s cerebellar cortex, which is the brain’s topmost outer layer. In particular, Purkinje cells are located in the outer layer of the cerebellum. The cerebellum is a structure located at the back of the brain and is responsible for maintenance of balance and posture, coordination of voluntary movement, motor learning, and cognitive functions including language, visuospatial, memory, and task planning and organizing.

In the cerebellum, Purkinje cells work to reduce the firing of neurons that receive inputs from them. Purkinje cells inhibit the activity of deep cerebellar nuclei which relay information from the cerebellar cortex to the thalamus. Purkinje cells are the sole output of all motor coordination in the cerebellar cortex. The cerebellum is a key relay in the establishment of fine motor control.

What do Purkinje cells do? What might they have an effect on?

Purkinje cells themselves are implicated in motor control and learning, and are the only neurons that send signals out of the brain’s cerebellar cortex; as inhibitory GABAergic neurons, Purkinje cells block other neurons from transmitting impulses. Dozens of Purkinje cells converge on a single nucleus in the deep cerebellum; it is thought that the inhibition provided by Purkinje cells serves as a timing signal to modulate downstream behavior and provide precise neuronal control of motor behaviors for the brain’s thalamus, which plays a critical role in the brain’s motor control network.

Purkinje cells play a crucial role in the brain in the coordination of complex motor and cognitive processes and disruptions to these cells’ function is associated with many diseases and disorders. Loss of Purkinje cells is associated with other diseases including Niemann Pick disease type C and cerebellar essential tremor. Neurodegenerative diseases including Alzheimer’s disease and Huntington’s disease involve the progressive loss of brain cells including Purkinje cells. Recent work suggests that disruptions to Purkinje cells may be responsible for symptoms of Autism as well (Sudarov, 2013).

What type of cannabis plant has an effect on Purkinje cells?

All cannabis that contains the psychoactive compound delta-9-tetrohydrocannabinol, or delta-9-THC, affects the brain mainly by activating one of the two known endocannabinoid receptors in the brain. The primary target of cannabinoids and endocannabinoids in the brain is the CB1 receptor. The CB1 receptor is an endocannabinoid receptor primarily localized to the brain and found in the cerebral cortex as well as abundantly in the cerebellum. CB1 is primarily located presynaptically in the most superficial layer of the cerebellar cortex.

Endocannabinoids such as 2-arachidonoylglycerol (2-AG) can be released by Purkinje cells and contribute to retrograde signaling of neurons. Retrograde signaling is a process by which the endocannabinoid acts “backwards” to signal from the synapse back to the cell body; typical neuronal signaling travels outward from the cell body to the synapses. Retrograde transmission allows neurons to create feedback loops to enhance neurotransmission rather than actually distribute information; in this way, THC has a modulatory effect on Purkinje cells and in the brain. The endocannabinoids anandamide and 2-AG are thought to play an important role in modulatory retrograde signaling in the formation of new memories.

Because THC also binds to endocannabinoid receptors, it is likely that cannabis can impact retrograde signaling in the cerebellar Purkinje cells as well. Over the past 25 years, scientists have learned a lot about the effects of cannabis, and specifically, THC, on neuronal activity. THC has many diverse effects on various brain systems involving reward, cognition, perception, and movement. Subchronic THC exposure was shown to result in impaired eyeblink conditioning and motor control in mice, and the THC-induced behavioral impairments observed were related to a fast downregulation of CB1 receptors in the cerebellum.

It is thought that endocannabinoid signaling is disrupted by THC due to changes in neurotransmitter release from the neurons that project to Purkinje cells, rather than due to changes to Purkinje cells themselves. In the cerebellum, CB1 receptors are expressed on the terminals of fibers that project to Purkinje cells, and are thought to regulate synaptic plasticity processes. CB1 receptors inhibit the release of glutamate in the cerebellar cortex, and the decrease in CB1 receptor activity results in overall increase in excitatory, or glutamatergic, activity. Repeated cannabis exposure affects cerebellar-mediated associative learning, but not other types of learning that do not involve the cerebellum. Therefore, research indicates that cerebellar function is highly affected by the consumption of cannabis, and the resulting downregulation of the endocannabinoid receptor CB1.

Altered time perception is frequently reported by THC users and this could be linked to temporal disintegration that is linked to an increase in internal clock speed by a mechanism that involves cerebellar function as well.

[Note: I don’t know how open source this photo is, but you may consider using Ramon y Cajal’s original drawings on your website – this is from Wikipedia, so I think it is Public Domain, but I don’t know about fair use for images on commercial blogs. Anyway, here is the link, in case it is useful for your blog: https://en.wikipedia.org/wiki/Neuron#/media/File:PurkinjeCell.jpg]

Sources used to write the article on “why do we have Cannabinoid receptors?":

Where is marijuana native to?

From where does marijuana originate?

If you are wondering where is marijuana native to, this is the article for you. Cannabis sativa, the marijuana plant, is thought to have originated in Central Asia, in what is now Mongolia and south Siberia. People have been using cannabis for over 12,000 years, which means that cannabis is one of the world’s oldest cultivated crops. Ancient Greeks and Romans were familiar with cannabis, and later, in the Middle East, cannabis use spread throughout the Islamic empire and North Africa.

Where is marijuana indigenous?

Cannabis sativa was originally found in the Caucuses of eastern Europe, as well as India and Iran. Today, it can be found growing all over the world in warm to temperate regions which are amenable to plant life.

How did marijuana migrate?

Burned cannabis seeds have been found in burial mounds in Siberia from 3,000 BC, and in the tombs of nobility buried in China and Siberia in 2500 BC. Hemp and marijuana were both used by ancient Chinese as a medicine. Marijuana arrived in Korea about 1000 years later, in 2000 BC, and made its way to the South Asian subcontinent in 1000 BC. Cannabis was used throughout India as a calming drug in ancient times. The anxiolytic properties of marijuana were lauded in an ancient Sanskrit poem whose name can be translated, in English, to “Science of Charms”: in this poem, marijuana is elevated to one of “five kingdoms of herbs…which release us from anxiety.”

Between 2000 and 1400 BC, cannabis made its way to Europe. In the Middle East, cannabis spread through the Islamic empire to North Africa. In 1545, Spaniards imported cannabis to Chile to use it as a fiber. In North America, hemp was grown on many plantations to be used in clothing and fiber.

Eventually, in the early 1900s, cannabis ended up in the United States. Marijuana was brought to the United States from Mexico when immigrants fled the country during the Mexican Revolution of 1910-1911.

Who was the first user or users of marijuana and what was the intended use?

According to written records, the Chinese Emperor Shen Nung was the first to use cannabis in 2727 BC. Ancient Greeks and Romans also were familiar with the cannabis plant making it one of the first places where marijuana is native to.

The first users of marijuana were located in Central Asia – specifically, what is now Mongolia and eastern Europe. In its early use, marijuana was used medicinally for many purposes. Marijuana proved, in particular, to be a powerful anesthetic, and the Vikings and medieval Germans later used cannabis to relieve toothaches and the pain associated with childbirth.

Sources used in answering the question what are the origins of marijuana and where marijuana is native to.

In what states is medical marijuana legal?

Marijuanas Legal States are numerous. 29 states, the District of Columbia, Guam, and Puerto Rico have legalized medical and/or recreational use of marijuana. Each state has different rules and regulations on how the medical marijuana is dispensed. Many states also enable patients to cultivate a limited amount of marijuana in their homes.

How many states have medical cannabis?

29 states and Washington, D.C. currently have laws legalizing medical marijuana on the books.

In states where medical cannabis is not legal, are other forms of marijuana derivatives legal, such as CBD?

Many states which have not legalized cannabis have laws on the books that legalize CBD. Alabama, Georgia, Indiana, Iowa, Mississippi, Missouri, South Carolina, Tennessee, Virginia, Wisconsin, and Wyoming all have legalized the use of cannabis extracts containing CBD to treat severe and debilitating conditions such as seizures or epilepsy. Other states, such as Idaho, Texas, or Oklahoma, have not legalized medical marijuana or marijuana derivative use of any kind.

What states have legal recreational cannabis?

Although medical marijuana is legal in 29 states and the District of Columbia, many states have been reluctant to legalize the smoking of marijuana and prefer instead to legalize prescription cannabis medicines. The states that have legalized the use of recreational cannabis are Alaska, California, Colorado, Maine, Massachusetts, Nevada, Oregon, and Washington. In other states, it is only legal to obtain a certain amount of marijuana for medical purposes only and only through the approval of a licensed primary care provider.

In what states is medical marijuana legal?

The states in which medical marijuana is legal are: Alaska, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, Florida, Hawaii, Illinois, Maine, Maryland, Massachusetts, Michigan, Minnesota, Montana, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Dakota, Ohio, Oregon, Pennsylvania, Rhode Island, Vermont, Washington, West Virginia, and the District of Columbia. Read on to find out more about marijuana laws and legalization in each state.

When and how did medical marijuana become legal in medical marijuana states?

Most states legalized medical marijuana through ballot initiatives. Medical marijuana was also approved by ballot initiative in the District of Columbia, whose budget is controlled by Congress. In DC, legalization efforts stalled due to the criticism of the legalization by federal lawmakers, but the first DC resident obtained marijuana from a DC-run dispensary in 2013. A few states have legalized the recreational use of marijuana through ballot initiatives as well.

What’s legal and what are the limitations of legal use?

While state law has made medical marijuana use legal in 29 of 50 states, federal law classifies marijuana as an illegal drug. Therefore, federal law enforcement officers may arrest anyone on federal lands for possession or use of any amount of marijuana. Marijuana consumption and use must also happen outside of public areas. Certain states allow the cultivation of marijuana plants in residences, but there are limitations on this as well, such as a maximum number of plants or a maximum number of mature or flowering plants allowed to be maintained at one time.

Selling marijuana is illegal in all states except by a licensed medical or recreational marijuana dispensary that is approved by the state. Possessing more than the legal upper limit of marijuana as specified by the state is also illegal. Federal law classifies marijuana as a Schedule I substance according to the Controlled Substances Act, so it is illegal to transport marijuana across state lines, even if the states traveled through have all legalized the medical or recreational use of marijuana.

State and federal law prohibit the use of marijuana, alcohol, or any other mind-altering substances while operating a car, boat, or other vehicles. Driving under the influence of cannabis, alcohol, or other mind-altering substances is also illegal.

What you need to qualify for medical cannabis?

To qualify for medical cannabis, most states require registration with the state’s medical marijuana registry or system. This typically requires the approval of a physician and the filing of an application which may include the submission of a drivers’ license, photo, and/or application fee in addition to a written statement from the patient’s primary health care provider. In some cases, caregivers of patients may be able to join the medical marijuana system as well.

Read on to learn more about medical marijuana legalization rules and regulations in each state.

Marijuanas Legal States: District of Columbia

Both recreational and medical marijuana is legal in DC for individuals 21 years of age or older; individuals can possess 2 ounces of less of marijuana for private use. More information about D.C.’s medical marijuana program can be found here.

MARIJUANAS LEGAL STATES Alaska

Both recreational and medical marijuana are legal in AK, thanks to an Alaska Supreme Court decision and a voter-approved ballot initiative, respectively. A person who is at least 21 years old can possess 1 oz. or less of marijuana. Information about the Medical Marijuana registry of Alaska can be found here.

MARIJUANAS LEGAL STATES Arizona

Medical marijuana was legalized by a voter-approved ballot measure in 2011. Arizonans can possess up to 2.5 oz. of usable marijuana. More information on medical marijuana in AZ is available here.

MARIJUANAS LEGAL STATES Arkansas

Medical marijuana was legalized by a voter-supported ballot initiative in November 2016. Qualified patients or designated caregivers can purchase up to 2.5 oz. from a dispensary every 14 days. More information is available from the Arkansas Department of Health here.

MARIJUANAS LEGAL STATES California

Both recreational and medical marijuana are legal in CA. In 1996, California was the first state to legalize medical marijuana through a voter-supported ballot initiative. Adults over the age of 21 can possess up to 1 oz. of pot. More information about participating in California’s medical marijuana program is available through the California Department of Public Health.

MARIJUANAS LEGAL STATES: Colorado

Both recreational and medical marijuana are legal in CO, thanks to voter-approved ballot initiatives. Coloradoans above the age of 21 can legally possess 1 oz. of marijuana. More information about Colorado’s medical marijuana program is available here.

Connecticut Joins MARIJUANAS LEGAL STATES

The Connecticut State Senate legalized medical marijuana in 2012. Under the law, patients of at least 18 years of age can buy 2.5 ounces of medical cannabis a month.

Delaware Joins MARIJUANAS LEGAL STATES

Delaware’s state legislature legalized medical marijuana in 2011. A registered medical marijuana patient can possess six ounces of cannabis at once and obtain up to three ounces of marijuana every 14 days. More information about Delaware’s medical marijuana program is available here.

Florida Joins Marijuanas Legal States List

Florida’s voters approved a ballot measure legalizing medical cannabis in 2016. Patients can possess a limited supply (30-45 days worth) of medical or low-THC cannabis at once. More information about FL medical marijuana is here.

Hawaii Joins Marijuanas Legal States List

HI’s state legislature legalized medical cannabis in 2000, and patients can possess up to 4 oz of usable cannabis. More information about HI medical marijuana is here.

Illinois Joins Marijuanas Legal States List

IL legalized medical marijuana by state legislature in 2013; patients can possess 2.5 oz. of cannabis in a 14-day period. More information about IL medical marijuana programs are here.

Maine Joins Marijuanas Legal States List

Maine has legalized both recreational and medical marijuana. Medical marijuana was legalized through a ballot initiative in 1999, and voters recreational use was recently approved by a ballot measure in 2017. Persons above the age of 21 can own up to 2.5 oz. of marijuana for private use. More information on ME’s medical marijuana program is here.

Maryland added to Marijuanas Legal States List

Maryland legalized medical marijuana in 2014 by state legislature. However, medical cannabis is not yet available in this state. More information on MD’s medical marijuana program is here.

Massachusetts

MA has legalized both recreational and medical marijuana. Medical marijuana was approved by the state legislature in 2012, and in 2017, voters approved the recreational use of marijuana by ballot measure. Adults 21 age or older can possess one ounce of cannabis outside of their residence and up to ten oz. of marijuana inside their residence. More information about MA’s medical marijuana program is here.

Michigan

Michigan voters approved a ballot measure in 2008 to legalize medical marijuana. Each patient can possess up to 2.5 oz. of marijuana. More information about the Michigan Medical Marihuana Program is here.

Minnesota

MN’s state legislature legalized cannabis in 2014. Each patient can have a 30-day supply of medication but smoking is not an approved method of use. More information about Minnesota’s Medical Marijuana program is here.

Montana

Montana legalized medical cannabis by ballot measure in 2004. Medical marijuana cardholders can possess up to 1 oz. of marijuana. More information about MT medical marijuana is here.

Nevada

Nevada has decriminalized both recreational and medical marijuana. NV approved medical marijuana by a ballot initiative in the late 1990s. Adults over the age of 21 can own up to 1 oz. of marijuana and up to 3.5 grams of cannabis concentrates. More information about NV’s medical marijuana program is here.

New Hampshire

New Hampshire legalized medical marijuana by state legislature in 2013. Patients can possess up to 2 oz. of marijuana. More information about NH’s Therapeutic Cannabis Program is available here.

New Jersey

New Jersey legalized medical marijuana by state legislature in 2010. NJ patients are limited to 2 ounces in a 30 day period. More information about New Jersey’s medical marijuana program can be found here.

New Mexico

New Mexico legalized medical cannabis in 2007. Eight ounces are medical cannabis are available to patients over a 90 day period. To learn more about the medical cannabis program in NM, click here.

New York

New York’s state legislature legalized medical cannabis in 2014. A 30-day supply of non-smokable cannabis is available to patients. To learn more about the medical cannabis program in NY, click here.

North Dakota

North Dakota legalized medical cannabis by ballot initiative in 2016. Patients can obtain 3 oz. of medical cannabis. More information about medical marijuana in ND is available here.

Ohio

Ohio legalized medical cannabis by state legislature in 2016. Possession laws have not yet been specified. To learn more about medical marijuana practices in OH, click here.

Oregon

Both recreational and medical use of marijuana are decriminalized in Oregon. Medical marijuana became legal in 1998 thanks to a ballot initiative. Patients can own up to twenty-four ounces of cannabis. To learn more about medical marijuana programs in OR, click here.

Pennsylvania

Medical marijuana was approved by state legislature in PA in 2016. Only a 30-day supply is allowed, and no smoking of marijuana is permitted – only oils, topical creams, etc., are allowed. To learn about the medical marijuana program in Pennsylvania, click here.

Rhode Island

Medical marijuana was decriminalized in Rhode Island by state legislature in 2006. Patient can possess 2.5 ounces for private use in their home. To learn more about Rhode Island’s medical marijuana programs, click here.

Vermont

Medical marijuana was legalized in VT in 2004. Patients can be prescribed up to two ounces of usable marijuana to be used privately in their homes. To learn more about Vermont’s medical marijuana program, click here.

Washington

Both medical and recreational marijuana is legalized in Washington State. Medical cannabis became legal through a voter initiative in 1998. The medical marijuana patient registry program is voluntary but enables patients to own 3 ounces of useable marijuana, and provides restrictions on solid and liquid forms of marijuana products as well. To learn more about Washington’s medical marijuana program, click here.

West Virginia

Medical marijuana was legalized in WV by state legislature in 2017. Patients may be prescribed a 30-day supply of medications. To learn more about West Virginia’s Medical Marijuana Program, click here. While WV’s medical marijuana program is not currently operational yet, it enables patients to seek forms of marijuana for medical treatments that do not include smoking marijuana, such as oils, creams, pills, nebulizers, etc.

There are many different types of cannabinoids and they can be separated into different categories; today we will explore CBD vs CBN. Over 60 cannabinoids have been isolated and identified from the cannabis sativa plant, which is most commonly known as marijuana. Cannabidiol (CBD) and Cannabinol (CBN) are two subcategories of cannabinoid compounds that are found in cannabis.

What is CBD and what does it do in the body?

Cannabidiol, or CBD, is the most abundant cannabinoid in cannabis sativa – it comprises up to 40% of cannabis resin. However, CBD doesn’t produce a “high” like other compounds in cannabis, and because of this, it is typically used for medical reasons rather than recreationally. CBD produces anxiolytic effects which are thought to minimize the hallucinogenic effects of the psychoactive compound THC which is abundant in cannabis. CBD interacts with the human endocannabinoid neurotransmitter system to suppress production of the endogenous cannabinoid anandamide, therefore blocking the “high” feelings obtained from cannabis, and specifically, THC. Metabolically, CBD results in a longer action of THC at a lower intensity due to its competitive inhibition of THC. CBD may also inhibit the metabolism of enzymes in the liver, which can be dangerous for people who take medications affecting the Cytochrome P450 system in liver cells but also throughout the body.

What is CBN and what does it do in the body?

Cannabinol, or CBN, is a product that is created when the cannabis plant is exposed to air, and, like CBD, can also have an antagonistic effect on the psychoactive properties associated with THC. CBN is thought to decrease the potency of the cannabis plant – when exposed to air, the THC in cannabis sativa oxidizes and forms the compound CBN. Laboratory research has identified CBN’s potential as an anticonvulsant and anti-inflammatory medication. CBN is a weak partial agonist at CB1 and CB2, the two cannabinoid receptors. Unlike CBD, CBN’s metabolic effects are not well understood.

Where are CBN and CBD found and how are they different?

CBN and CBD are both compounds found in the cannabis sativa, or marijuana, plant. The two compounds are functionally similar in that they both are thought to mitigate the psychoactive effects of THC. However, CBN and CBD are two distinct compounds which have many differences. CBN is the oxidative by-product of THC and appears after long storage, when the plant is exposed to oxygen. CBD, on the other hand, is already present in cannabis sativa and does not appear after oxidation. Another difference is how the compounds are treated within the endocannabinoid system. CBD directly acts on the endocannabinoid system to block the production of the endogenous cannabinoid anandamide. CBN, on the other hand, is created by the exposure of marijuana to air and the degradation of THC. While CBD influences the receptor binding and metabolism of THC, it does not have a well-identified direct effect on the cannabinoid system and instead is simply an oxidative byproduct of the psychoactive compound THC.

What are the possible uses/treatment of CBD vs CBN?

Lets look at possible uses of CBD vs CBN. CBD can be taken orally, applied topically as a lotion, and sometimes inhaled as a vapor or used intravenously. CBD has been shown to reduce chronic inflammation and pain in some animal studies, and is currently used by patients of multiple sclerosis and fibromyalgia to reduce their chronic pain symptoms. CBD may also help people stop abusing cigarettes and even opioids, but helping ease some of the withdrawal symptoms associated with cessation. Finally, CBD may also play a therapeutic role in epilepsy, neurodegeneration, and severe anxiety disorders such as Post-Traumatic Stress Disorder. CBD has also been studied for its potential role as an anti-cancer agent; CBD may suppress the growth of cancer cells. CBD is an attractive option for many people struggling with these diseases because the legal medicines available on the market often come with a host of unpleasant and unwanted side effects, while CBD does not have the same side effect profile.

CBN, while less studied for its clinical potential, has been shown to be an anticonvulsant, anti-inflammatory, anti-MRSA, and a reducer of keratinocyte proliferation, stimulation of bone formation.

What are the possible side effects of CBD and CBN?

CBD inhibits many metabolic processes, including inhibition of the cytochrome P450 metabolism for many drugs. Therefore, CBD may increase the bioavailability of certain classes of drugs including macrolides, calcium channel blockers, antihistamines, haloperidol, and sildenafil.

What are the current CBD products on the market?

The CBD market is rapidly expanding; last year, the market was worth $202 million. In 2015, the total market for hemp-derived CBD products was $90 million, and the market for marijuana-derived CBD products was $112 million.

The Drug Enforcement Administration (DEA) maintains that CBD is an illegal substance, just like other marijuana products. While hemp oil is legal in all 50 states, the DEA maintains that both CBD oil or what marketers call “hemp-derived CBD oil” is not legal everywhere. The legal definition of items that are considered to be marijuana includes oil derived from cannabis seeds or anything derived from the oil that is made from cannabis seeds.

In states with medical marijuana laws on the books, CBD can be obtained with a prescription. Many companies sell a variety of CBD-based products, including CBD oil, chewing gum, energy drops meant to be mixed into one’s water, lotion, capsules, and CBD oil that is produced either from hemp or cannabis. Prescription: Medical Marijuana, Inc., offers prescription CBD oil for epilepsy, Alzheimer’s Disease, Parkinson’s Disease, chronic pain, and migraines.

What are the current CBN products on the market?

CBN has been used as a sleep aid for people who have insomnia. Individuals who have a medical weed prescription sometimes make sure to use high-CBN strains at night or allow their cannabis to oxidize, to enable them to sleep better at night. Currently, no prescription medications isolating CBN have been introduced to the market, although therapeutic potential may exist. Limited evidence indicates that CBN can help stimulate bone growth in addition to a host of other medical benefits.