"Numb3rs" follows the story of dedicated FBI agent Don Eppes (Rob Morrow), who recruits his mathematical-genius younger brother, Charlie (David Krumholtz), to help solve a wide range of crimes in Los Angeles.

Inspired by actual events, the two brothers, who couldn't be more different, take on the most perplexing criminal cases, using a mix of police work and mathematics to provide surprising revelations and solutions to the most confounding criminal questions.