Ironically, considering the site, the guides seem to favor the Genesis for these games. Though the guide for Separation Anxiety is strictly for the Genesis version, and doesn't do as good a job going over the basics of controls, the controls really aren't switched up between the 2 games, so looking over the controls for Maximum Carnage will give you the control scheme for Separation Anxiety.

If you want to survive these highly challenging games, try to find the secret areas, which often lead to healing items and extra lives.