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Vitamin and Supplements Regimen

Are there any guidelines about the safe doses of Vitamin B-6? I am a bit confused: some of you mentioned taking 50mg or 100mg daily, and many products offer high doses (I was for instance considering this supplement: Daily Essential Nutrients - A Natural Alternative For Mood Disorders, which would provide 66mg per day), but in my home country the official recommendation is to avoid exceeding 5mg per day because of the potential neurotoxicity.

Is it sensible to take B-12 and B-6 separately, in order to get a high dose of B-12 and a low of B-6? Or is the balance important?

B-6 at 5 mgs per day is OK. It is the B-12 that is more important. Folate (folic acid) is also important. Getting the whole range of Bs with low dose B-6 is a challenge. That is why I suggest a B-50 Complex plus B-12.

100 mgs of B-6 daily is considered the very lowest range for toxicity with B-6 not usually a problem until 1000 mgs per day is taken.

That Daily Essential Nutrients is killer expensive at $1.50 US per daily dose (4 capsules each day). It only has 23 mgs of B-6 in a daily dose of 4 capsules.

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