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Neural fibrolipoma

Mason (1953)Also called fibrolipomatous hamartoma of nerve, perineural lipoma, fatty infiltration of the nerve, intraneural lipoma, lipomatosis of nerveDue to infiltration and hypertrophy of mature fibrofatty tissue infiltrating epi and perineuriumCommonly present at birth or early childhood, and most present before 30 years of ageNon-hereditaryMedian nerve is most commonly involved (more than 80%). 2nd most common ulnar nerve. Other reported nerves include brachial plexus, radial, peroneal nervesUsually less than 30 years age

Clinical features:Soft, slowly enlarging mass in the palmar aspect of the hand, wrist or forearm since childhoodPainNeurological symptomsAssociated macrodactyly = macrodystrophia lipomatosa, usually involves 2 and 3rd digits, in 27-67%

Radiography:Soft-tissue swelling and bone overgrowth, usually of 2 and 3rd digits, may show bowingSecondary degenerative changes may be seen

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