Cells, Tissues, and Disease

Principles of General Pathology

Second Edition

Guido Majno and Isabelle Joris

This book lays out the principles of general pathology for biomedical researchers, grad students, medical students, and physicians, with elegance and deep insight. Disease processes are explained in the light of malfunctions at the cellular level, offering a rich understanding of the clinical correlates of all aspects of fundamental cellular physiology and basic biomedicine. The book has been fully revised and updated to present a current but deep understanding of disease states at the cell and tissue levels - cellular pathology, inflammation, immunopathology vascular disturbance, and tumor biology.

Cells, Tissues, and Disease

Principles of General Pathology

Second Edition

Guido Majno and Isabelle Joris

Description

This book lays out the principles of general pathology for biomedical researchers, grad students, medical students, and physicians, with elegance and deep insight. Disease processes are explained in the light of malfunctions at the cellular level, offering a rich understanding of the clinical correlates of all aspects of fundamental cellular physiology and basic biomedicine. The book has been fully revised and updated to present a current but deep understanding of disease states at the cell and tissue levels - cellular pathology, inflammation, immunopathology vascular disturbance, and tumor biology.

Cells, Tissues, and Disease

Principles of General Pathology

Second Edition

Guido Majno and Isabelle Joris

Table of Contents

Introduction Part I: Cellular Pathology 1. The long road to the elementary patient2. Cellular adaptations3. Symptoms of cellular disease: Intracellular accumulations4. Pathology of the organelles5. Cell injury and cell death6. Pathologic calcification7. Extracellular pathologyPart II: Inflammation 8. Introduction to inflammation9. Inflammation: The actors and their language10. The four cardinal signs of inflammation11. Leukocytes called to action: Steps to Phagocytosis12. The inflammatory exudate13. Chronic inflammation14. Wound healing15. General effects of local injury and inflammation16. Variations and aberrations of the inflammatory responsePart III:Immunopathology 17. Hypersensitivity reactions18. Pathology of transplantation19. Autoimmune disease20. Immunosuppression21. Disturbances of fluid exchange22. Hemostasis and thrombosis23. Obstacles to blood flow24. Ischemia and shockPart V: Tumors 25. Tumors: Names and personalities26. Anatomy and biology of tumors27. Tumor aggression28. The causes of tumors29. Genes and tumors30. Antitumor defenses31. The reversability of tumors32. Epidemiology of cancer33. What is a tumor?34. Tumors as a clinical problem

Cells, Tissues, and Disease

Principles of General Pathology

Second Edition

Guido Majno and Isabelle Joris

Reviews and Awards

"The authors have collaborated closely over many decades. As a result...this [textbook] is cohesively and tighly written with uniformity of style and presentation. ...and the delightful, flowing language comes as a breath of fresh air. It is highly recommended for any beginning or intermediate course in biomedical sciences and pathology." --JAMA

". . .a pleasant surprise for a textbook of general pathology. Well-written and a pleasure to read."--ACP News