Bradykinin

Bradykinin is an inflammatory mediator.
It is a physiologically and pharmacologically active peptide of the kinin group of proteins, consisting of nine amino acids.

There are two forms of bradykinin receptors – B1 and B2. B1 is less present constitutively, but may be upregulated in chronic inflammation. B2 receptors are abundant in most tissues.
Stimulation of these receptors activate C polymodal receptors and cause nociception.

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