Breast Cancer one of the appalling diseases among the middle-aged women and it is a foremost threatening death possibility cancer in women throughout the world. Earlier prognosis and preclusion reduces the conceivability of death. The proposed system beseech various data mining techniques together with a real-time input data from a biosensor device to determine the disease development proportion. Surface acoustic waves (SAW) biosensor empowers a label-free, worthwhile and straight detection of HER-2/neu cancer biomarker. The output from the biosensor is fed into the proposed system as an input along with data collected from Winconsin dataset. The complete dataset are processed using data mining classification algorithms to predict the accuracy. The exactness of the proposed model is improved by ranking attributes by Ranker algorithm. The results of the proposed model are highly gifted with an accuracy of 79.25% with SVM classifier and an ROC area of 0.754 which is better than other existing systems. The results are used in designing the proper drug thereby improving the survivability of the patients.