Harboring a Grudge

Your first mission for Packie can be acquired by heading to the "P" on your map. This "P" is located in the borough of Dukes, on Savannah Avenue alongside the southern end of Meadow Park. Once you get there and head inside, you'll meet Packie, his mother, and his sister (who seems to take a liking to Niko, and vice-versa). The demented and abusive conversation that ensues while inside will give you a little hint as to why Francis, Packie's brother, is so off-base. However, Packie will have a job for Niko if he's interested in taking it, and the two head out of the house.

Your destination is over the bridge in Algonquin, on Privateer Road alongside the east end of the island. To get there, the HUD will bring you over the Algonquin Bridge via Colony Island. As you head over, Packie and Niko will have a lengthy conversation about all sorts of things, and the two new friends seem to take quite a liking to each other. They have an especially disturbing conversation about prison, as you will see. Anyway, when you reach your location under the raised highway on Privateer Road in Algonquin, pull into the arrow as seen on the HUD and on-screen.

Packie will explain the plan briefly and then get out of the car, so you should get out of your car and follow him. He'll bring you alongside a waterside warehouse, and the two of you will begin climbing up to the roof. Follow the on-screen prompts, as you'll need to jump up on things, boost yourself up, shimmy across chasms, and all that jazz. This acts as a sort of tutorial, though it's a little late in the game to be of any use. Anyway, once on the roof, Packie and Niko will observe a boat coming in to the dock, and the two will resolve to steal the meds being loaded onto a truck parked nearby.

When you regain control, you'll be told by an in-game prompt to jump down to the area below and get fighting, but we highly recommend that you resist that urge if you have a sniper rifle in your inventory. With the sniper rifle, you can clear out a great deal (if not almost all) of the enemies waiting down below for you. This will make your life much, much easier, since these guys are all armed with automatic weapons and can potentially tear you apart if you go down there without thinning them out. Take aim from various areas on the roof to get a full vantage point of the area below and kill whoever you see. That sniper rifle is useful!

After clearing out a substantial amount of enemies (or, after regaining control and killing what enemies you can with other weapons in your inventory), you can jump down to the area below and begin working your way towards the garage where the truck is parked. Use what cover you can once down on the ground level to block any remaining enemy bullets, and keep an eye on all sides so that you aren't surprised by anyone you didn't see earlier. The cops are probably on to you by this point, as well, since you've been shooting willy-nilly for so long, so you're going to have to deal with them in addition.

With the enemies outside of the warehouse holding the truck eliminated, you can then focus on any holdouts inside the garage. Some will make themselves seen from the get-go, while others will only make themselves seen as you near the garage or enter it. So, keep your weapon at the ready and cap any foes that make themselves seen as you run towards the truck. When the coast is clear, you can then hijack the truck, pick up Packie en route (keeping in mind that cops in the area will pull you out of the truck and arrest you if you aren't careful), and then get going, pounding through the chain link fence to the road on the other side.

The drive to the garage where you have to drop the truck off is not a smooth one. Even if you're being chased by the police, however, the HUD will still give you some direction as to where you have to go (which is to a garage located off of Union Drive West on the west side of Algonquin). At the very least, you're going to have the criminals you stole from on your tail, and at worst, you'll have the cops on you as well. Thankfully, if the latter is on you, the HUD will still show you where you need to go. Grenades will be found in the truck as the drive proceeds, allowing you to toss them out the window to stymie the advance of your enemies, as well. The truck can take a lot of damage, however, so there's really not much to worry about in terms of getting to the lockup in one piece.

When you arrive, park the truck in the garage. Then, Packie will congratulate Niko on a job well done. An Italian mobster will then drive up and ask Packie if all is well with the mission, and he tells him that everything is fine. He then introduces Niko to the mobster, letting him know that he was integral in successfully stealing the meds. After letting Niko know that he may be in touch with you, the mobster then invites Packie into the car, and the two take off. You're on your own, with another successful mission under your belt.