There came a girl to the big city
Now she wasn’t all that pretty
She didn’t see anyone like her
Not one clique cared for her
What would you do in a situation such?
She did the same, stayed quiet much.
Queen B Bacteriodes had a perfect pout
Her girl gang would follow her around

Lactobacillus tweeted I need no fuss
So you see this girl got really lonely
Thought ‘why nobody wants to be friends with me?’
She laid low, didn’t get carried away
By all the shallow trends in her way
Didn’t do shit just to get accepted
Chilled out despite being neglected
Then came in the ravishing Salmonella

If this was a fairytale, she was Bella

Within 12-36hrs she got all the attention
Charmed the people of the gut with her Vi so fine
Told stories of strange lands & how with her the host loves to dine
The enchanted flora onlooked as she swam
In her flagella bikini without giving a damn
But the dean of St. Bowel High School didn’t agree
Said ‘This is a prestigious Gut, not a fashion spree!’
Sent Salmi to Payer‘s for detention, called for diarrhea disciplinary
Well it’s highschool, crazy things happen
From the sky a lot of Antibiotics started fallin’
It was a catastrophe, I still hear the cries
In this story eventually everyone dies.

The gut hallways empty, every flora wiped out
No Peptococcus to flirt, No wannabe Bacteriodes to pout
Nobody survived, but one forgotten soul
That new girl without friends all so lone
She made it through the antibiotic storm
Without the mean girls around she got in her form
And just when I thought things will heal,
She revealed her name is Clostridium Difficile!

Charged and entoxicated with new power in her hands
She painted the town with pseudomembranous sands
The shy little creature was shy no more
Wicked rather, like a crooked whore
With an evil grin concocted toxin A&B
It’s always the quiet ones, you see!
As the legend goes her tyranny did end
Since special force Capt. Metronidazole was sent
His funny sidekick Sporlac took care of the rest
And finally there was peace as you might have guessed.

The use of systemic antibiotics, including (but not limited to) any penicillin-based antibiotic such as ampicillin, cephalosporins, and clindamycin, causes the normal bacterial flora of the bowel to be altered. In particular, when the antibiotic kills off other competing bacteria in the intestine, any bacteria remaining will have less competition for space and nutrients. The net effect is to permit more extensive growth than normal of certain bacteria. Clostridium difficile is one such type of bacterium. In addition to proliferating in the bowel, C. difficile also produces toxins. Without either toxin A or toxin B, C. difficile may colonize the gut, but is unlikely to cause pseudomembranous colitis.[24] The colitis associated with severe infection is part of an inflammatory reaction, with the “pseudomembrane” formed by a viscous collection of inflammatory cells, fibrin, and necrotic cells.