C-X-C motif chemokine 1 (CXCL1)

Links to databases

CXCL1 is a chemokine that upon binding to its receptor CXCR2 elicits chemotactic activity on neutrophils and among others is involved in inflammatory response. CXCL1 has been described to be involved in several inflammation-related diseases such as inflammatory bowel disease, systemic lupus erythematosus, E. coli-associated renal inflammation, etc.

NOTE: The calibrator curve below shows the performance of the assay with the estimated sensitivity and dynamic range parameters indicated. These curves are generated during the assay validation process using recombinant antigens. Please note that when analyzing biological samples the data generated will be given in the form of relative quantification (NPX values) and cannot be converted to absolute protein concentrations. For more info about NPX measurements, please visit our FAQ page.

Analytical Measuring Range

LOD (pg/mL)

7.63

LLOQ (pg/mL)

30.52

ULOQ (pg/mL)

31250

Hook (pg/mL)

31250

Range (logs)

3

Calibrator curve generated in multiplex

Precision

Within run precision Coefficient of Variation (CV)

7%

Between run precision Coefficient of Variation (CV)

12%

Precision (repeatability) is calculated from linearized NPX values over LOD.

Biomarker Validation Data

Additional validation data, as well as a more detailed description of how the Olink panels are quality controlled can be found in our Data Validation documents. To download or to learn more go to the Data Validation page.