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Northwest of Cerulean City. It is located in Kanto and was first introduced in Gen I. You must have beaten the Pokémon League to enter. If you use Surf and try to get in a Cooltrainer will block it until you have beaten all the gym leaders in the Kanto region. This is the only place to catch Mewtwo. The Mewtwo is at Lv 70.

Contents

Items

Generation I

Pokémon Red, Green and BlueFull Restore: on the riverbank near the southwest corner of the first floor; center of the second floorMax Elixir: on the riverbank on the first floorMax Revive: north edge of the basementNugget: near the northwest corner of the first floorPP Up: east edge of the second floorUltra Ball: southwest corner of the second floor; center of the basementPokémon YellowFull Restore: east edge of the second floorMax Elixir: west of the entrance on the first floor; north edge of the basementMax Revive: east edge of the first floor; southeast of the second floor's center; center of an elevated area in the basementRare Candy: southeast corner of the first floor; west edge of the second floorUltra Ball: center of the first floor; center of the second floor; center of an elevated area in the basement; northeast corner of the basement

Generation III

Full Restore: on the riverbank near the southwest corner of the first floor; against the eastern edge of the second floorMax Elixir: near the center of the first floorMax Revive: in the northeast corner of the basementNugget: in the northwest corner of the first floorPP Up: near the southwest corner of the second floorUltra Ball: near the southeast corner of the second floor; near the center of the basement

Trivia

In Generation I, any Pokémon that can only be found in the Cerulean Cave is listed as "area unknown" in the Pokédex. This was fixed in Generation III, however. Whether this was intended or just a glitch is unknown (most likely a glitch).Though its design varies with each iteration, the version of it found in Pokémon FireRed and LeafGreen and Pokémon HeartGold and SoulSilver is very heavily similar to the one in the original Pokémon Red and Green, which was never released outside of Japan. The only difference is the Generation III addition of Rock Smash boulders.