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Take the streetcar that is going Northbound to Spadina Station. The fare is CAN$3.00. Get off at the Willcocks Street stop. Total trip time from Union Station is around 15 minutes. Wilson Hall Residence is on the north-east corner at 40 Willcocks Street.

From the Metro Toronto Bus Terminal:

The Metro Toronto Bus Termianl is located on Bay, just north of Dundas. Take the Westbound Dundas streetcar (ask for a transfer) until you reach Spadina Avenue intersection.
Get off, and take the Northbound Spadina streetcar until you reach the Willcocks stop. Streetcar fare is CAN$3.00, and the toal trip time is around 15 minutes. Wilson Hall Residence is on the north-east corner.

From Pearson International Airport:

The quickest and easiest way to get to New College Wilson Hall Residence from Pearson Internatonal is by airport taxi. If you ask for a flat rate to New College Residence, University of Toronto (intersection - Spadina/Willcocks, just north of College Street), it will cost around CAN$48-$55. Total trip time depending on traffic will be around 45 minutes to over an hour.