Scamander carries a magical briefcase with him that contains numerous dangerous beasts. When he accidentally leaves the case open and creatures escape, it's up to him to contain them before any no-maj (American muggles) find out.

Scroll down for our breakdown of everything we spotted in the new trailer.

The trailer opens with Newt Scamander onboard a ship heading towards New York City.

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A voiceover, likely Colin Farrell's character — an auror named Graves — says: "You’re an interesting man, Mr. Scamander. Just like your suitcase, I think there’s much more to you than meets the eye."

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A creature attempts to wriggle out of Newt's briefcase, which magically expands inside to contain his "fantastic beasts."

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"Kicked out of Hogwarts, for endangering human life with a beast," Graves says. This is new information ... perhaps Newt's expulsion is the reason why he's taken a trip to the US.

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Sounds like Newt has something in common with everyone's favorite gamekeeper, Hagrid, who was wrongfully expelled for releasing a basilisk in the school.

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"Yet one of your teachers argued strongly against your expulsion," Graves says. Another thing in common with Hagrid: Newt had an ally in Albus Dumbledore.

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"I wonder, what makes Albus Dumbledore so fond of you, Mr. Scamander?" Dumbledore was the Transfiguration professor at Hogwarts before becoming Headmaster. Clearly, Newt was one of his students, and a favored one at that.

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Newt stands at the boat's docking area, where immigrants are processed.

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He approaches the inspector, clearly nervous.

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A critter in his case unlatches one hook, and Newt scrambles to seal it again.

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He flicks a lock setting to "Muggle Worthy," hoping to get the case through customs.

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The customs officer asks a series of questions to the nervous and stammering Newt. "First trip to America? Anything edible in there? Any livestock?"

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When the officer opens the case, no beasts are visible. Just a regular man's luggage.

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The stern-looking man says "Welcome to New York."

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Newt breathes in relief. He's in.

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While in New York, Newt meets Porpentina "Tina" Goldstein, a witch who works for the Magical Congress of the United States of America (MACUSA).

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Here's a look inside the MACUSA headquarters in New York City. A group of men is hurrying across the room ... trouble is brewing.

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Based on this newspaper we see, there appears to be an ongoing issue of "wizarding exposure" to the no-maj (American muggles).

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Then we get a glimpse of Newt's other companions. On the left here is Jacob Kowalski, an American no-maj who finds himself in the company of wizards.

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They are entering a secret room with Porpentina and her sister (on the right) Queenie.

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Kowalski seems shocked to see magic performed for the first time.

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He and Newt appear to be houseguests of Porpentina and Queenie.

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At the end of the trailer we see them sharing a room.

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Kowalski is enjoying some tea in bed. On the bookshelf to the right is a volume called "Living with Legilimins." We know Queenie is a legilimens (meaning she can see into minds like Snape and Voldemort).

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Kowalski looks on as Newt opens his briefcase, and climbs inside of the magically expanded room.

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Newt climbs down, as if there is a staircase inside.

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He beckons to Kowalski, indicating he should follow suit.

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Kowalski doesn't seem keen on the idea.

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Back on the New York streets, there's an important political fundraiser taking place.

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It looks like a gathering in honor of someone named Senator Shaw, likely a no-maj man.

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But as he addresses the crowd, the chandeliers overhead explode. Something's not right.

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We see doors exploding inwards, and people go flying.

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Someone — or something — is wreaking havoc.

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The camera zooms overheads, as if from the point of view of a beast, as people fling themselves out of the way. Is this one of Newt's escaped creatures?

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Outside again, police seem to be bracing themselves against an attack.

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In an underground area, we see Newt and Porpentina with a bird of some sort. "Harry Potter" fan site Pottermore confirmed this is a new creature called the "Swooping Evil."

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Here's a look at the bird in action.

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The same bird appears to make up the "S" in the word "Beasts" from the movie titles.

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Porpentina and Newt are running away from a pair of wizards.

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Dressed like 1920s detectives, our guess is these men are American Aurors.

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Here's one of them apparating into a room.

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We get a strange shot of a young girl flinging something into the air. A bird, maybe? Birds seem to be a popular theme in the trailer.

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Here's our first clear look at Colin Farrell's character, Graves.

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And here's another shot of Newt in the streets, looking concerned.

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More concerned-Newt. Judging on the light shining on his face, and the train tracks behind him, this might be a NYC subway station.

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Graves is in the same station, fiercely casting a spell at something.

In a more lighthearted moment, we see Newt's pet — a Niffler! These creatures were first introduced in "Harry Potter and the Goblet of Fire." They are cuddly, and love treasure. Newt's niffler seems to be digging into a purse.

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But Graves speaks again, warning the MACUSA leader about a specific beast. "No human could do what this thing’s capable of," he says.

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He's warning Seraphina, the wizard-President of the US. Based on his phrasing, Graves seems to be emphasizing that no-majs will know the destruction is coming from a magical source.

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And finally, another apparition shot of Newt. He leaps off the roof of a building and vanishes into thin air.

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Watch the full trailer again below. "Fantastic Beasts" hits theaters November 18, 2016.