PR3SERPIN A1 levels were similar in males and females, and in those with or without previous histories of hypertension, angina, AMI or heart failure, but were slightly elevated in those with diabetes [547.0 (76.94035.5) ng/ml] compared with non-diabetic patients [495.1 (29.33118.2) ng/ml; P<0.018].

PURPOSE: The purpose of this study was to investigate adverse reaction reports of pain and/or cyanosis attributed to alpha 1-proteinase inhibitor (A1PI), a plasma alpha-globulin protein used to treat A1PI deficiency.