A scientific look at bad science

A study in the Proceedings of the National Academy of Sciences reviewed 2,047 retractions of biomedical and life-sciences articles and found that just 21.3 percent stemmed from straightforward error, while 67.4 percent resulted from misconduct, including fraud or suspected fraud (43.4 percent) and plagiarism (9.8 percent).

Surveys of scientists have tried to gauge the extent of undiscovered misconduct. According to a 2009 meta-analysis of these surveys, about 2 percent of scientists admitted to having fabricated, falsified, or modified data or results at least once, and as many as a third confessed “a variety of other questionable research practices including ‘dropping data points based on a gut feeling,’ and ‘changing the design, methodology or results of a study in response to pressures from a funding source’ ”.