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Phone:

00351253601515

Position:

Assistant Professor/Researcher

Research Group:

Innovation for Life - Functional Genomics and Nanobiotechnology for Sustainable Living

Research Line/Work:

Microbial Functional Genomics

Work Address:

CBMA-Centre for molecular and environmental biology
Department of Biology
University of Minho
Campus de Gualtar
4710-087 Braga - Portugal

Current Research & Key Publications

Current Work:

Currently, I am leading a research team in Bacterial Functional Genomics. Our research is strongly engaged in Systems Biology approaches using Pseudomonas selected isolates. Bacteria belonging to the Pseudomonas genus possess an intricate ability to tolerate and thrive in challenging environments such as the Human lungs, the deep sea or highly polluted soils. Such competence resides in their wide nutritional and metabolic versatility and in a complex network of adaptation mechanisms. In other words, the necessary code to efficiently cope with a wide variety of different substrates and biotic and/or abiotic stress conditions is included in their genomic catalog. Therefore, they hold great potential, as a source of novel biomolecules and cell factories, for different biotechnological applications, namely in the fields of biocatalysis, biosensors, bioremediation, and biomedicine. So far, we have sequenced the full genomes of 3 Pseudomonas isolates and set a variety of in silico and wet-lab approaches to explore the genome catalogs of the sequenced isolates, including genome assembly and annotation pipelines, RNA-Seq, expression proteomics and metabolomics approaches.

The main topics of research are:i) Systems and synthetic biology approaches to enhance Pseudomonas biotech potential

ii) Metagenomic characterization of microbiomes from soil and cetaceans

Title: Exploitation of immunogenic proteins of the Burkholderia cepacia complex to design new diagnostic and therapeutic strategiesFunding: FCT- PTDC/BBB-BIO/1958/2012Period: 2013-2015Role: Team member (responsible of the research activities at University of Minho)

Title: ROOT-INT- Role of a two-component regulatory system in the early interaction between Sinorhizobium meliloti and plant root hairsFunding: FCT-PTDC/BIA-MIC/113733/2009 Period: 2011-2014Role: Team member (responsible of the research activities at University of Minho)

Title: NANOECOTOX-Impacts of metal nanoparticles to aquatic ecosystems: from community responses to cellular targetsFunding: PTDC/AAC-AMB/121650/2010 (2012-2015)Period: 2012-2015Role: Team member