The article discusses the origin and treatment strategies of necrobiosis lipodica diabeticorum. The disease was described as a chronic granulomatous dermatitis with no known cause. It commonly develops among patients aged 30-40 years old and has a female-male ratio of 3:1. The disease, which is associated with Chrohn's disease, ulcerative colitis and sadarcoidosis also develops in patients with diabetes. It usually appears as yellow-red plaques with telangiectatic vessels, central atrophy and raised violet-coloured edges on the shins and the back of the hands. Therapeutic options include glucocorticoids or psoralen plus ultraviolet A photochemotherapy, while new treatment strategies include cyclosporin A and infliximab.

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27603081

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