Magnetization transfer ratio (MTR) is a magnetic resonance imaging (MRI) method which may detect
demyelination not detected by conventional MRI in the central nervous system of patients with multiple
sclerosis (MS). A ...

Mass spectrometry based protein profiling and biomarker discovery has given rise to
the field of clinical proteomics. The underlying assumption is that proteins can
provide information of diagnostic or therapeutic value ...

Objective. To evaluate the acceptability and efficacy of medical abortion at home up to 63 days&rsquo; gestation without limits on travel distance to a registered institution.
Design. Observational prospective study.
Setting. ...

Introduction: Children with cerebral palsy (CP), one of the most common childhood neurological disorders, often have associated
medical and psychological symptoms.This study assesses mental health problems compared to ...

Introduction: The prevalence of pediatric obesity has increased worldwide during the last decades, and is currently a serious health challenge, as it causes extensive health problems in terms of cardiovascular comorbidities ...

Background
Intracranial arachnoid cysts (AC) are membranous sacs filled with CSF-like fluid that are commonly found in the temporal fossa. The majority of ACs are congenital. Typical symptoms are headache, dizziness, and ...

Background
The prevalence of microembolic signals (MES) during the acute phase of ischemic stroke and its influence on outcome is not well studied. The aim of our study was to determine the prevalence of MES, the different ...

Oral cancer, represented mainly by oral squamous cell carcinoma (OSCC), is the eighth most common type of human cancer worldwide. The number of new OSCC cases is increasing worldwide, especially in the low-income countries, ...

Background: Molecular studies of immunoglobulin (IG) genes have provided
insights into the pathogenesis of different lymphoid malignancies and allowed the
development of useful diagnostic tools as well as powerful ...

The gene encoding mt-tRNALeu(UUR), MT-TL1, is a hotspot for pathogenic mtDNA mutations. Amongst the first to be described was the 3302A>G transition which resulted in a substantial accumulation in patient muscle of RNA19, ...

Objective: Polymerase gamma (POLG) mutations are a common cause of mitochondrial disease and have also been linked to neurodegeneration and aging. We studied the molecular mechanisms underlying POLG-related neurodegeneration ...

Objective: We sought to investigate various molecular subtypes defined by genomic instability that may be related to early death and recurrence in colon cancer.
Methods: We sought to investigate various molecular subtypes ...

Molecular subtyping of breast cancer may provide additional prognostic information regarding patient outcome. However, its clinical significance remains to be established. In this study, the main aims were to discover ...

A month of birth effect on multiple sclerosis (MS) risk has been reported from different countries. Recent critics have suggested that this finding is caused by confounding and that adequately adjusting for year and place ...

Background: Health effects of diving have been observed in divers who have not experienced any diving related accidents. The aim of the study was to study total, and cause specific mortality, in Norwegian retired professional ...

Purpose: Based on a clinical observation, this study was initiated to examine whether treatment with lamotrigine (LTG) is associated with an increased risk of sudden unexpected death in epilepsy (SUDEP) in sub-groups of ...

Background: Mosaic whole-chromosome tetrasomy has not previously been described as a cause
of fetal malformations.
Case presentation: In a markedly dysmorphic child with heart malformations and developmental
delay, CGH ...