DERMAL (LIQUID) - Defatting of the skin with irritation, dryness, erythema, and cracking commonly occur. Blistering may occur, particularly if exposure to concentrated xylene is prolonged and the exposed area of skin is occluded.

OCULAR - Brief exposure to high vapor concentrations can cause a sensation of irritation. Vacuolar keratopathy has occurred in a few workers with prolonged exposure to high vapor concentrations. Splash accidents have produced transient, superficial injury in most cases. Older literature reports conjunctivitis and occasionally corneal burns following eye contact with liquid xylene.