Norvir

"The study of 18 patients is the first to show that the drug does not require the presence of herpes simplex virus 2 (HSV-2) to suppress HIV in patients. The researchers hope to confirm their results in a larger study.

Norvir

DRUG-DRUG INTERACTIONS
LEADING TO POTENTIALLY SERIOUS AND/OR LIFE THREATENING REACTIONS

Co-administration of NORVIR
with several classes of drugs including sedative hypnotics, antiarrhythmics, or
ergot alkaloid preparations may result in potentially serious and/or
life-threatening adverse events due to possible effects of NORVIR on the hepatic
metabolism of certain drugs. Review medications taken by patients prior to
prescribing NORVIR or when prescribing other medications to patients already
taking NORVIR [see CONTRAINDICATIONS, WARNINGS
AND PRECAUTIONS, DRUG INTERACTIONS, and CLINICAL
PHARMACOLOGY].

DRUG DESCRIPTION

Ritonavir is chemically designated as
10-Hydroxy-2-methyl-5-(1-methylethyl)-1-[2-(1methylethyl)-4-thiazolyl]-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic
acid, 5-thiazolylmethyl ester, [5S-(5R*,8R*,10R*,11R*)]. Its molecular formula is
C37H48N6O5S2, and its
molecular weight is 720.95. Ritonavir has the following structural formula:

Ritonavir is a
white-to-light-tan powder. Ritonavir has a bitter metallic taste. It is freely
soluble in methanol and ethanol, soluble in isopropanol and practically
insoluble in water.

What are the precautions when taking ritonavir capsules, oral solution (Norvir)?

Before taking ritonavir, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.