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Philadelphia • Given a second chance, Lawrence Tynes couldn't make the Philadelphia Eagles pay for a tactical gamble that nearly backfired.

Tynes missed two field-goal tries from 54 yards with 15 seconds left and Philadelphia held on for a 19-17 victory over the New York Giants on Sunday night.

Tynes missed wide left on his first attempt, but the Eagles had called a timeout to ice him. He was short on his second attempt.

"When you're surrounding by 66,000 people that probably wanna rip your head off, yeah," Eagles coach Andy Reid said when asked if he regretted the timeout.

With LeSean McCoy leading the way on the ground, Michael Vick guided Philadelphia (3-1) to another comeback.

Alex Henery kicked a 26-yard field goal with 1:49 left, and the Eagles overcame two pass interference penalties on New York's final drive.

The defending Super Bowl champion Giants (2-2) have struggled against Philadelphia, losing eight of the last nine meetings.

McCoy ran for 121 of his 123 yards rushing in the second half.

"It's just the Giants and Eagles, this is what it comes down to," McCoy said. "Eventually our running game would crack it, and that's what we did."

After Eli Manning tossed a go-ahead 6-yard TD pass Bear Pascoe, Vick drove the Eagles to the Giants 2 before Osi Umenyiora sacked him for a 6-yard loss on third down. Henery then hit his fourth field goal to put the Eagles ahead to stay.

A pass interference penalty on Dominique Rodgers-Cromartie kept the Giants' last drive alive and put the ball at the Eagles 35 after Manning threw an incomplete pass on fourth-and-1. Another pass interference call on Nnamdi Asomugha on third-and-10 moved it to the Eagles 27.

Then Ramses Barden got called for offensive pass interference to move it back to the 36.

After an incomplete pass, the Giants sent out Tynes to try for the winning kick.

"I don't believe in icing the kicker. Let him step up there and do what he does," Vick said. Eagles 19,Giants 17