The SCOLISCORE Test

The SCOLISCORE Test

The SCOLISCORE Test is a new, simple saliva test that is changing how doctors evaluate scoliosis. With the help of genetic science and other diagnostic information, physicians can now reliably predict which children diagnosed with mild adolescent idiopathic scoliosis (AIS) have a low likelihood of progression to severe scoliosis – a condition that could require years of treatment.

The SCOLISCORE Test, when combined with other diagnostic criteria, has the potential to reduce the number of physician visits and repeated x-ray exposure for the lowest risk patients – nearly 75% of the patient population – as well as provide greater peace of mind to parents and children whose scoliosis has a low likelihood of progression.

From a saliva sample, the SCOLISCORE Test identifies the genetic risk factors associated with severe scoliosis and assigns a numerical value between 1 and 200. Patients who score 50 or less are considered low risk patients.

The SCOLISCORE Test utilizes 53 DNA markers found to be linked to the progressive form of scoliosis.

Results are returned to the administering physician in two to three weeks.

Backed by clinical data from nearly 10,000 scoliosis patients worldwide, the SCOLISCORE Test has been shown to be 99% predictive for children who score in the low risk group – the majority of patients. Those who score in the intermediate or high risk groups are expected to continue to be closely monitored for curve progression.

Scoliosis affects about 7 million people in the U.S., most of them children between the ages of 10 and 15.

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