I think ASCA is an antibody in the blood that attacks a particular bacteria that is sometimes very prevelant in Crohn's patients. But I'm not sure if high levels indicate Crohn's or the opposite.I am a pre-30yr. old who has been diagnosed with Crohn's for 14 years. Symptoms change from cramping and weight loss to severe anemia with fatigue and diarrhea.

I'm DONE (D-O-N-E, DONE!!!) with immuno-suppressants. Tremble, yee Pharmacuetical companies, for you will not withstand the aggressive onslaught of our healing!

I have the exact same problem..asca igg was high.. iga was normal...past all other tests for chrons. I just went to the doctor for a physical and now I have done 5 different tests including colonoscopy..pill cam..Doctor says I am fine.. Only symptoms I have is slight constipation sometimes. Also have a sudden increase in acne which is strange for 28yrs old. Please I would love to hear a update on this subject from anyone. I know all the info online says 95 percent conclusive for crohns so I have been super stressed.

I had strongly positive ASCA antibodies about 5 years ago when I had a rare form of colitis they "said" was diverticular colitis. I had to have surgery and was symptoms free for about 4 years but now, I am having symptoms again. I don't even want to go in for all the darn testing again. I think I have crohn's in there somewhere. I have joint pain, fatigue, and occasional low grade fevers. My rheumatologist thinks they missed the crohn's somehow. I hear sometimes it can be hard to find unless it's pretty prominent in the biopsy.d 1/09 with colitis sigmoid colon with some diverticular disease as well, Colon resection Nov. 2010, in remission for 4 years but think it's coming back-:)))))) inflammatory arthritis, type 2 d, asthma, skin scleroderma, hashimoto's thyroid diseaseMeds: VSL#3 probiotic, Vit. D, nexium, synthroid, metformin, fenofibrate, Positive ANA speckled pattern 1:180, high sed r

If you have high levels of ASCA and your acne flares when you have issues, you should find a well-educated specialist to investigate the possibility of Behçet's disease. "Acne" is a common manifestation, and it can be accompanied by gastrointestinal problems. Higher than normal ASCA levels can indicate Behçet's as well, but it's ultimately a diagnosis of exclusion. Are you near any good teaching hospitals? If so, I would do some digging to see if anyone familiar with Behçet's can see you.