This patent describes methods of treating, e.g., reducing, ameliorating or preventing, skin damage induced by UVB, etc., by decreasing the level or activity of VEGF-A in the skin of a subject. In one aspect, the invention features compositions containing an agent that decreases the expression, activity or level of VEGF-A or VEGFR. In a preferred embodiment, the composition is applied in a cosmetic composition for topical administration.

Method and compositions are provided in this invention for treating or preventing a skin pathology or disorder associated with diabetes and/or aging. Topical administration of at least one agent capable of restoring an impaired physiological condition of the skin is described, such as PKC modulating agents, various adipokines and insulin signaling-related molecules. In particular, the inventors noted the restoration of subcutaneous adipose tissue can overcome many diabetic skin pathologies and aging skin disorders and conditions.

This patent discloses compositions having antioxidant and anti-inflammatory activity that in one aspect are derived by exposing a berry to an acidic solvent composition, adding a cryoprotectant and recovering a berry extract having a stabilized anthocyanin content. Compositions comprising the stabilized anthocyanin-containing berry extract, formulated for oral and/or topical administration, are also provided.

According to this invention, a topical vasodilation composition can be applied to skin affected by at least one abnormal blood vessel to non-invasively disrupt the tissue architecture, e.g., by inducing ischemia to promote healing.

Cosmetic compositions with anti-free radical activity are disclosed in this patent. Such compositions preferably contain an association of at least the following three substances: idebenone, N-acetylcysteine and alpha-tocotrienol or an ester thereof, with a C2-C4 organic acid.

These inventors discuss a method and system for noninvasive face lifts and deep tissue tightening. The method and treatment system are configured for imaging, monitoring and thermal injury to treat the SMAS facial region. First, the region of interest is imaged for localization of the treatment area and surrounding structures. Second, ultrasound energy is delivered at a depth, distribution, timing and energy level to achieve the desired therapeutic effect. Lastly, the treatment area is monitored before, during, and after therapy to plan and assess the results and/or provide feedback.

Provided herein are compositions of sandalwood heartwood oil and methods of making and using such compositions for the treatment of skin disorders such as acne, rosacea, psoriasis, eczema, dermatitis--i.e., atopic dermatitis and seborrheic dermatitis, dandruff, diaper rash or fungal infections.

Described by this patent is a botanical antioxidant composition including a first extract comprising at least one hydroxycinnamic acid, and at least one additional antioxidant extract comprising one or more antioxidants selected from the group consisting of vitamins, stilbenoids, curcumininoids, tannins, flavones, fiavonols, flavan-3-ols, flavanones, anthocyanidins, anthocyanins, isoflavones, flavanonols, proanthocyanidins, dihydroxybenzoic acids and pyridine alkaloids.