Between the frontiers of the three super-states Eurasia, Oceania, and Eastasia, and not permanently in possession of any of them, there lies a rough quadrilateral with its corners at Tangier, Brazzaville, Darwin, and Hongkong. These territories contain a bottomless reserve of cheap labour. Whichever power controls equatorial Africa, or the Middle East or Southern India or the Indonesian Archipelago, disposes also of the bodies of hundreds of millions of ill-paid and hardworking coolies, expended by their conquerors like so much coal or oil in the race to turn out more armaments, to capture more territory, to control more labour, to turn out more armaments, to capture more territory, to control…Thus George Orwell—in his only reference to the less-developed world.I wish I could disagree with him. Orwell may have erred in not anticipating the withering of direct colonial controls within the “quadrilateral” he speaks about; he may not quite have gauged the vehemence of urges to political self-assertion. Nor, dare I hope, was he right in the sombre picture of conscious and heartless exploitation he has painted. But he did not err in predicting persisting poverty and hunger and overcrowding in 1984 among the less privileged nations.I would like to live to regret my words but twenty years from now, I am positive, the less-developed world will be as hungry, as relatively undeveloped, and as desperately poor, as today.

Dilbert: Maybe I’m unlucky in love because I’m so knowledgeable about science that I intimidate people. Their intimidation becomes low self-esteem, then they reject me to protect their egos.Dogbert: Occam’s Razor.Dilbert: What is “Occam's Razor”?Dogbert: A guy named Occam had a rule about the world. Basically he said that when there are multiple explanations for something the simplest explanation is usually correct. The simplest explanation for your poor love life is that you’re immensely unattractive.Dilbert: Maybe Occam had another rule that specifically exempted this situation, but his house burned down with all his notes. Then he forgot.Dogbert: Occam’s Razor.Dilbert: I’m an idiot.Dogbert: I don’t think we can rule it out at this point.

Enlightenment is man’s emergence from his self-incurred immaturity. Immaturity is the inability to use one's own understanding without the guidance of another. This immaturity is self-incurred if its cause is not lack of understanding, but lack of resolution and courage to use it without the guidance of another. The motto of enlightenment is therefore: Sapere aude! Have courage to use your own understanding!

From the original French in Traité élémentaire de chimie (1789, 1793), discours préliminaire, ix; and from edition translated into English by Robert Kerr, as Elements of Chemistry (1790), Preface, xvii.

Original German from 'Der Mensch' (1849), collected in Gesammelte abhandlungen zur wissenschaftlichen medicin (1856), 6. Webmaster used Google translate for the English version. This longer quote unites the shorter quotes from within it shown separately on the Rudolf Virchow quotations page, with alternative translations, which begin: “There can be no scientific dispute…”, “Belief has no place…”, and “The task of science…”.

A ... hypothesis may be suggested, which supposes the word 'beginning' as applied by Moses in the first of the Book of Genesis, to express an undefined period of time which was antecedent to the last great change that affected the surface of the earth, and to the creation of its present animal and vegetable inhabitants; during which period a long series of operations and revolutions may have been going on, which, as they are wholly unconnected with the history of the human race, are passed over in silence by the sacred historian, whose only concern with them was largely to state, that the matter of the universe is not eternal and self-existent but was originally created by the power of the Almighty.

A celebrated author and divine has written to me that “he has gradually learnt to see that it is just as noble a conception of the Deity to believe that He created a few original forms capable of self-development into other and needful forms, as to believe that He required a fresh act of creation to supply the voids caused by the action of His laws.”

A cell has a history; its structure is inherited, it grows, divides, and, as in the embryo of higher animals, the products of division differentiate on complex lines. Living cells, moreover, transmit all that is involved in their complex heredity. I am far from maintaining that these fundamental properties may not depend upon organisation at levels above any chemical level; to understand them may even call for different methods of thought; I do not pretend to know. But if there be a hierarchy of levels we must recognise each one, and the physical and chemical level which, I would again say, may be the level of self-maintenance, must always have a place in any ultimate complete description.

A formative influence on my undergraduate self was the response of a respected elder statesmen of the Oxford Zoology Department when an American visitor had just publicly disproved his favourite theory. The old man strode to the front of the lecture hall, shook the American warmly by the hand and declared in ringing, emotional tones: ‘My dear fellow, I wish to thank you. I have been wrong these fifteen years.’ And we clapped our hands red. Can you imagine a Government Minister being cheered in the House of Commons for a similar admission? “Resign, Resign” is a much more likely response!

A life that stood out as a gospel of self-forgetting service.He could have added fortune to fame but caring for neither he found happiness and honor in being helpful to the world.The centre of his world was the south where he was born in slavery some 79 years ago and where he did his work as a creative scientist.

A man who keeps company with glaciers comes to feel tolerably insignificiant by and by. The Alps and the glaciers together are able to take every bit of conceit out of a man and reduce his self-importance to zero if he will only remain within the influence of their sublime presence long enough to give it a fair and reasonable chance to do its work.

A principle of induction would be a statement with the help of which we could put inductive inferences into a logically acceptable form. In the eyes of the upholders of inductive logic, a principle of induction is of supreme importance for scientific method: “... this principle”, says Reichenbach, “determines the truth of scientific theories. To eliminate it from science would mean nothing less than to deprive science of the power to decide the truth or falsity of its theories. Without it, clearly, science would no longer have the right to distinguish its theories from the fanciful and arbitrary creations of the poet’s mind.” Now this principle of induction cannot be a purely logical truth like a tautology or an analytic statement. Indeed, if there were such a thing as a purely logical principle of induction, there would be no problem of induction; for in this case, all inductive inferences would have to be regarded as purely logical or tautological transformations, just like inferences in inductive logic. Thus the principle of induction must be a synthetic statement; that is, a statement whose negation is not self-contradictory but logically possible. So the question arises why such a principle should be accepted at all, and how we can justify its acceptance on rational grounds.

All truth passes through three stages. First, it is ridiculed. Second, it is violently opposed. Third, it is accepted as being self-evident. [Caution: expressed in this wording, it is likely misattributed.]

Schopenhauer did write a different reflection with this theme, much less tersely, on how the acceptance of truth has “only one short victory celebration is granted between the two long periods where it is despised as paradox and condemned as trivial.” See the Introduction to The World as Will and Representation (1819), xvi. The “three stages” quote is included here so it may be found with this caution: it is questionable that Schopenhauer expressed this idea with this wording. Although widely repeated, Webmaster has not yet found any citation to a primary source for these words. (Schopenhauer was German, so any quote in English represents a translation.) According to Ralph Keys, diligent search by scholars has found no written source in German, either. The sentiment has been variously restated and attributed to other authors. A somewhat better-documented version of the “three stages of truth” is attributed to Louis Agassiz, though still with only second-person references. See Ralph Keyes, The Quote Verifier (2006), 225-226.

Among natural bodies some have, and some have not, life; and by life we mean the faculties of self-nourishment, self-growth and self-decay. Thus every natural body partaking of life may be regarded as an essential existence; … but then it is an existence only in combination. … And since the organism is such a combination, being possessed of life, it cannot be the Vital Principle. Therefore it follows that the Vital Principle most be an essence, as being the form of a natural body, holding life in potentiality; but essence is a reality (entetechie). The Vital Principle is the original reality of a natural body endowed with potential life; this, however, is to be understood only of a body which may be organized. Thus the parts even of plants are organs, but they are organs that are altogether simple; as the leaf which is the covering of the pericarp, the pericarp of the fruit. If, then, there be any general formula for every kind of Vital Principle, it is—tthe primary reality of an organism.

And do you know what “the world” is to me? Shall I,show it to you in my mirror? This world: a monster of energy, without beginning, without end; a firm, iron magnitude of force that does not grow bigger or smaller, that does not expend itself but only transforms itself; as a whole, of unalterable size, a household without expenses or losses, but likewise without increase or income; enclosed by “nothingness”' as by a boundary; not by something blurry or wasted, not something endlessly extended, but set in a definite space as a definite force, and not a space that might be “empty” here or there, but rather as force throughout, as a play of forces and waves of forces, at the same time one and many, increasing here and at the same time decreasing there; a sea of forces flowing and rushing together, eternally changing, eternally flooding back, with tremendous years of recurrence, with an ebb and a flood of its forms; out of the simplest forms striving toward the most complex, out of the stillest, most rigid, coldest forms toward the hottest, most turbulent, most self-contradictory, and then again returning home to the simple out of this abundance, out of the play of contradictions back to the joy of concord, still affirming itself in this uniformity of its courses and its years, blessing itself as that which must return eternally, as a becoming that knows no satiety, no disgust, no weariness: this, my Dionysian world of the eternally self-creating, the eternally self-destroying, this mystery world of the twofold voluptuous delight, my “beyond good and evil,” without goal, unless the joy of the circle itself is a goal; without will, unless a ring feels good will toward itself-do you want a name for this world? A solution for all its riddles? A light for you, too, you best-concealed, strongest, most intrepid, most midnightly men?—This world is the will to power—and nothing besides! And you yourselves are also this will to power—and nothing besides!

And thus Nature will be very conformable to her self and very simple, performing all the great Motions of the heavenly Bodies by the Attraction of Gravity which intercedes those Bodies, and almost all the small ones of their Particles by some other attractive and repelling Powers which intercede the Particles. The Vis inertiae is a passive Principle by which Bodies persist in their Motion or Rest, receive Motion in proportion to the Force impressing it, and resist as much as they are resisted. By this Principle alone there never could have been any Motion in the World. Some other Principle was necessary for putting Bodies into Motion; and now they are in Motion, some other Principle is necessary for conserving the Motion.

And when with excellent Microscopes I discern in otherwise invisible Objects the Inimitable Subtlety of Nature’s Curious Workmanship; And when, in a word, by the help of Anatomicall Knives, and the light of Chymicall Furnaces, I study the Book of Nature, and consult the Glosses of Aristotle, Epicurus, Paracelsus, Harvey, Helmont, and other learn'd Expositors of that instructive Volumne; I find my self oftentimes reduc’d to exclaim with the Psalmist, How manifold are thy works, O Lord? In wisdom hast thou made them all.

André Weil suggested that there is a logarithmic law at work: first-rate people attract other first-rate people, but second-rate people tend to hire third-raters, and third-rate people hire fifth-raters. If a dean or a president is genuinely interested in building and maintaining a high-quality university (and some of them are), then he must not grant complete self-determination to a second-rate department; he must, instead, use his administrative powers to intervene and set things right. That’s one of the proper functions of deans and presidents, and pity the poor university in which a large proportion of both the faculty and the administration are second-raters; it is doomed to diverge to minus infinity.

Anybody who looks at living organisms knows perfectly well that they can produce other organisms like themselves. This is their normal function, they wouldn’t exist if they didn’t do this, and it’s not plausible that this is the reason why they abound in the world. In other words, living organisms are very complicated aggregations of elementary parts, and by any reasonable theory of probability or thermodynamics highly improbable. That they should occur in the world at all is a miracle of the first magnitude; the only thing which removes, or mitigates, this miracle is that they reproduce themselves. Therefore, if by any peculiar accident there should ever be one of them, from there on the rules of probability do not apply, and there will be many of them, at least if the milieu is reasonable. But a reasonable milieu is already a thermodynamically much less improbable thing. So, the operations of probability somehow leave a loophole at this point, and it is by the process of self-reproduction that they are pierced.

From lecture series on self-replicating machines at the University of Illinois, Lecture 5 (Dec 1949), 'Re-evaluation of the Problems of Complicated Automata—Problems of Hierarchy and Evolution', Theory of Self-Reproducing Automata (1966).

As to giving credit to whom credit is due, rest assured the best way to do good to one’s-self is to do justice to others. There is plenty for everybody in science, and more than can be consumed in our time. One may get a fair name by suppressing references, but the Jewish maxim is true, “He who seeks a name loses fame.”

Before Kuhn, most scientists followed the place-a-stone-in-the-bright-temple-of-knowledge tradition, and would have told you that they hoped, above all, to lay many of the bricks, perhaps even the keystone, of truth’s temple. Now most scientists of vision hope to foment revolution. We are, therefore, awash in revolutions, most self-proclaimed.

Biology … is the least self-centered, the least narcissistic of the sciences—the one that, by taking us out of ourselves, leads us to re-establish the link with nature and to shake ourselves free from our spiritual isolation.

But in the heavens we discover by their light, and by their light alone, stars so distant from each other that no material thing can ever have passed from one to another; and yet this light, which is to us the sole evidence of the existence of these distant worlds, tells us also that each of them is built up of molecules of the same kinds as those which we find on earth. A molecule of hydrogen, for example, whether in Sirius or in Arcturus, executes its vibrations in precisely the same time. Each molecule, therefore, throughout the universe, bears impressed on it the stamp of a metric system as distinctly as does the metre of the Archives at Paris, or the double royal cubit of the Temple of Karnac ... the exact quantity of each molecule to all others of same kind gives it, as Sir John Herschel has well said, the essential character of a manufactured article and precludes the idea of its being external and self-existent.

By a recent estimate, nearly half the bills before the U.S. Congress have a substantial science-technology component and some two-thirds of the District of Columbia Circuit Court’s case load now involves review of action by federal administrative agencies; and more and more of such cases relate to matters on the frontiers of technology.If the layman cannot participate in decision making, he will have to turn himself over, essentially blind, to a hermetic elite. … [The fundamental question becomes] are we still capable of self-government and therefore freedom?Margaret Mead wrote in a 1959 issue of Daedalus about scientists elevated to the status of priests. Now there is a name for this elevation, when you are in the hands of—one hopes—a benevolent elite, when you have no control over your political decisions. From the point of view of John Locke, the name for this is slavery.

By the early 1960s Pauling had earned a reputation for being audacious, intuitive, charming, irreverent, self-promoting, self-reliant, self-involved to the point of arrogance and correct about almost everything.

By their very nature chemical controls are self-defeating, for they have been devised and applied without taking into account the complex biological systems against which they have been blindly hurled.

Complex organisms cannot be construed as the sum of their genes, nor do genes alone build particular items of anatomy or behavior by them selves. Most genes influence several aspects of anatomy and behavior–as they operate through complex interactions with other genes and their products, and with environmental factors both within and outside the developing organism. We fall into a deep error, not just a harmful oversimplification, when we speak of genes ‘for’ particular items of anatomy or behavior.

Conformity-enforcing packs of vicious children and adults gradually shape the social complexes we know as religion, science, corporations, ethnic groups, and even nations. The tools of our cohesion include ridicule, rejection, snobbery, self-righteousness, assault, torture, and death by stoning, lethal injection, or the noose. A collective brain may sound warm and fuzzily New Age, but one force lashing it together is abuse.

Daniel Bernoulli used to tell two little adventures, which he said had given him more pleasure than all the other honours he had received. Travelling with a learned stranger, who, being pleased with his conversation, asked his name; “I am Daniel Bernoulli,” answered he with great modesty; “and I,” said the stranger (who thought he meant to laugh at him) “am Isaac Newton.” Another time, having to dine with the celebrated Koenig, the mathematician, who boasted, with some degree of self-complacency, of a difficult problem he had solved with much trouble, Bernoulli went on doing the honours of his table, and when they went to drink coffee he presented Koenig with a solution of the problem more elegant than his own.

Disinterestedness is as great a puzzle and paradox as ever. Indeed, strictly speaking, it is a species of irrationality, or insanity, as regards the individual’s self; a contradiction of the most essential nature of a sentient being, which is to move to pleasure and from pain.

Do we really wish to replace the fateful but impartial workings of chance with the purposeful self-interested workings of human will?Reported in 1981, expressing concern for the future of gene-splicing.

Dr. M.L. von Franz has explained the circle (or sphere) as a symbol of Self. It expresses the totality of the psyche in all its aspects, including the relationship between man and the whole of nature. It always points to the single most vital aspect of life, its ultimate wholeness.

Each of us has read somewhere that in New Guinea pidgin the word for 'piano' is (I use English spelling) 'this fellow you hit teeth belonging to him he squeal all same pig'. I am inclined to doubt whether this expression is authentic; it looks just like the kind of thing a visitor to the Islands would facetiously invent. But I accept 'cut grass belong head belong me' for 'haircut' as genuine... Such phrases seem very funny to us, and make us feel very superior to the ignorant foreigners who use long winded expressions for simple matters. And then it is our turn to name quite a simple thing, a small uncomplicated molecule consisting of nothing more than a measly 11 carbons, seven hydrogens, one nitrogen and six oxygens. We sharpen our pencils, consult our rule books and at last come up with 3-[(1, 3- dihydro-1, 3-dioxo-2H-isoindol-2-yl) oxy]-3-oxopropanoic acid. A name like that could drive any self-respecting Papuan to piano-playing.

Ecologically speaking, a spilt tanker load is like sticking a safety pin into an elephant’s foot. The planet barely notices. After the Exxon Valdez accident in Alaska the oil company spent billions tidying up the coastline, but it was a waste of money because the waves were cleaning up faster than Exxon could. Environmentalists can never accept the planet’s ability to self-heal.

Every great scientist becomes a great scientist because of the inner self-abnegation with which he stands before truth, saying: “Not my will, but thine, be done.” What, then, does a man mean by saying, Science displaces religion, when in this deep sense science itself springs from religion?

Faced with the admitted difficulty of managing the creative process, we are doubling our efforts to do so. Is this because science has failed to deliver, having given us nothing more than nuclear power, penicillin, space travel, genetic engineering, transistors, and superconductors? Or is it because governments everywhere regard as a reproach activities they cannot advantageously control? They felt that way about the marketplace for goods, but trillions of wasted dollars later, they have come to recognize the efficiency of this self-regulating system. Not so, however, with the marketplace for ideas.

Few men live lives of more devoted self-sacrifice than the family physician, but he may become so completely absorbed in work that leisure is unknown…. More than most men he feels the tragedy of isolation—that inner isolation so well expressed in Matthew Arnold’s line “We mortal millions live alone.”

Address to the Canadian Medical Association, Montreal (17 Sep 1902), 'Chauvinism in Medicine', published in The Montreal Medical Journal (1902), 31, 267. Collected in Aequanimitas, with Other Addresses to Medical Students, Nurses and Practitioners of Medicine (1904), 299.

Finally, in regard to those who possess the largest shares in the stock of worldly goods, could there, in your opinion, be any police so vigilant and effetive, for the protections of all the rights of person, property and character, as such a sound and comprehensive education and training, as our system of Common Schools could be made to impart; and would not the payment of a sufficient tax to make such education and training universal, be the cheapest means of self-protection and insurance?

Finally, since I thought that we could have all the same thoughts, while asleep, as we have while we are awake, although none of them is true at that time, I decided to pretend that nothing that ever entered my mind was any more true than the illusions of my dreams. But I noticed, immediately afterwards, that while I thus wished to think that everything was false, it was necessarily the case that I, who was thinking this, was something. When I noticed that this truth “I think, therefore I am” was so firm and certain that all the most extravagant assumptions of the sceptics were unable to shake it, I judged that I could accept it without scruple as the first principle of the philosophy for which I was searching. Then, when I was examining what I was, I realized that I could pretend that I had no body, and that there was no world nor any place in which I was present, but I could not pretend in the same way that I did not exist. On the contrary, from the very fact that I was thinking of doubting the truth of other things, it followed very evidently and very certainly that I existed; whereas if I merely ceased to think, even if all the rest of what I had ever imagined were true, I would have no reason to believe that I existed. I knew from this that I was a substance, the whole essence or nature of which was to think and which, in order to exist, has no need of any place and does not depend on anything material. Thus this self—that is, the soul by which I am what I am—is completely distinct from the body and is even easier to know than it, and even if the body did not exist the soul would still be everything that it is.

First, the chief character, who is supposed to be a professional astronomer, spends his time fund raising and doing calculations at his desk, rather than observing the sky. Second, the driving force of a scientific project is institutional self-aggrandizement rather than intellectual curiosity.[About the state of affairs in academia.]

For if there is any truth in the dynamical theory of gases the different molecules in a gas at uniform temperature are moving with very different velocities. Put such a gas into a vessel with two compartments [A and B] and make a small hole in the wall about the right size to let one molecule through. Provide a lid or stopper for this hole and appoint a doorkeeper, very intelligent and exceedingly quick, with microscopic eyes but still an essentially finite being.Whenever he sees a molecule of great velocity coming against the door from A into B he is to let it through, but if the molecule happens to be going slow he is to keep the door shut. He is also to let slow molecules pass from B to A but not fast ones ... In this way the temperature of B may be raised and that of A lowered without any expenditure of work, but only by the intelligent action of a mere guiding agent (like a pointsman on a railway with perfectly acting switches who should send the express along one line and the goods along another).I do not see why even intelligence might not be dispensed with and the thing be made self-acting.Moral The 2nd law of Thermodynamics has the same degree of truth as the statement that if you throw a tumblerful of water into the sea you cannot get the same tumblerful of water out again.

For that which can shewn only in a certain Light is questionable. Truth, ’tis suppos’d, may bear all Lights: and one of those principal Lights or natural Mediums, by which Things are to be view’d, in order to a thorow Recognition, is Ridicule it-self.Also seen in short form: “Ridicule is the test of truth.”

For the time of making Observations none can ever be amiss; there being no season, nor indeed hardly any place where in some Natural Thing or other does not present it self worthy of Remark: yea there are some things that require Observation all the Year round, as Springs, Rivers, &c. Nor is there any Season amiss for the gathering Natural Things. Bodies of one kind or other presenting themselves at all times, and in Winter as well as Summer.

For the first time there was constructed with this machine [locomotive engine] a self-acting mechanism in which the interplay of forces took shape transparently enough to discern the connection between the heat generated and the motion produced. The great puzzle of the vital force was also immediately solved for the physiologist in that it became evident that it is more than a mere poetic comparison when one conceives of the coal as the food of the locomotive and the combustion as the basis for its life.

For the saving the long progression of the thoughts to remote and first principles in every case, the mind should provide itself several stages; that is to say, intermediate principles, which it might have recourse to in the examining those positions that come in its way. These, though they are not self-evident principles, yet, if they have been made out from them by a wary and unquestionable deduction, may be depended on as certain and infallible truths, and serve as unquestionable truths to prove other points depending upon them, by a nearer and shorter view than remote and general maxims. … And thus mathematicians do, who do not in every new problem run it back to the first axioms through all the whole train of intermediate propositions. Certain theorems that they have settled to themselves upon sure demonstration, serve to resolve to them multitudes of propositions which depend on them, and are as firmly made out from thence as if the mind went afresh over every link of the whole chain that tie them to first self-evident principles.

For thousands of years men have striven and suffered and begotten and woman have brought forth in pain. A hundred years ago, perhaps, another man sat on this spot; like you he gazed with awe and yearning in his heart at the dying light on the glaciers. Like you he was begotten of man and born of woman. He felt pain and brief joy as you do. Was he someone else? Was it not you yourself? What is this Self of yours? What was the necessary condition for making the thing conceived this time into you, just you and not someone else?

For twenty pages perhaps, he read slowly, carefully, dutifully, with pauses for self-examination and working out examples. Then, just as it was working up and the pauses should have been more scrupulous than ever, a kind of swoon and ecstasy would fall on him, and he read ravening on, sitting up till dawn to finish the book, as though it were a novel. After that his passion was stayed; the book went back to the Library and he was done with mathematics till the next bout. Not much remained with him after these orgies, but something remained: a sensation in the mind, a worshiping acknowledgment of something isolated and unassailable, or a remembered mental joy at the rightness of thoughts coming together to a conclusion, accurate thoughts, thoughts in just intonation, coming together like unaccompanied voices coming to a close.

For undemocratic reasons and for motives not of State, they arrive at their conclusions—largely inarticulate. Being void of self-expression they confide their views to none; but sometimes in a smoking room, one learns why things were done.

Forty years ago the philosopher Alfred North Whitehead thought it self-evident that you would get a good government if you took power out of the hands of the acquisitive and gave it to the learned and the cultivated. At present, a child in kindergarten knows better than that.

From the freedom to explore comes the joy of learning. From knowledge acquired by personal initiative arises the desire for more knowledge. And from mastery of the novel and beautiful world awaiting every child comes self-confidence.

Furthermore, it’s equally evident that what goes on is actually one degree better than self-reproduction, for organisms appear to have gotten more elaborate in the course of time. Today's organisms are phylogenetically descended from others which were vastly simpler than they are, so much simpler, in fact, that it’s inconceivable, how any kind of description of the latter, complex organism could have existed in the earlier one. It’s not easy to imagine in what sense a gene, which is probably a low order affair, can contain a description of the human being which will come from it. But in this case you can say that since the gene has its effect only within another human organism, it probably need not contain a complete description of what is to happen, but only a few cues for a few alternatives. However, this is not so in phylogenetic evolution. That starts from simple entities, surrounded by an unliving amorphous milieu, and produce, something more complicated. Evidently, these organisms have the ability to produce something more complicated than themselves.

From lecture series on self-replicating machines at the University of Illinois, Lecture 5 (Dec 1949), 'Re-evaluation of the Problems of Complicated Automata—Problems of Hierarchy and Evolution', Theory of Self-Reproducing Automata (1966).

Given any rule, however “fundamental” or “necessary” for science, there are always circumstances when it is advisable not only to ignore the rule, but to adopt its opposite. For example, there are circumstances when it is advisable to introduce, elaborate and defend ad hoc hypotheses, or hypotheses which contradict well-established and generally accepted experimental results, or hypotheses whose content is smaller than the content of the existing and empirically adequate alternative, or self-inconsistent hypotheses, and so on.

His mother’s favorite, he [Freud] possessed the self-confidence that told him he would achieve something worth while in life, and the ambition to do so, though for long the direction this would take remained uncertain.

Historians constantly rewrite history, reinterpreting (reorganizing) the records of the past. So, too, when the brain's coherent responses become part of a memory, they are organized anew as part of the structure of consciousness. What makes them memories is that they become part of that structure and thus form part of the sense of self; my sense of self derives from a certainty that my experiences refer back to me, the individual who is having them. Hence the sense of the past, of history, of memory, is in part the creation of the self.

Humanity is about to learn that a lunatic (touched by the moon) is not a crazy man but one so sane, well-informed, well-coordinated, self-disciplined, cooperative and fearless as to be the first earthian human to have been ferried to a physical landing upon the moon, and thereafter to have been returned safely to reboard his mother space vehicle earth.

Humanity, in the course of time, had to endure from the hands of science two great outrages against its naive self-love. The first was when humanity discovered that our earth was not the center of the universe…. The second occurred when biological research robbed man of his apparent superiority under special creation, and rebuked him with his descent from the animal kingdom, and his ineradicable animal nature.

From a series of 28 lectures for laymen, Part Three, 'General Theory of the Neurons', Lecture 18, 'Traumatic Fixation—the Unconscious' collected in Sigmund Freud and G. Stanley Hall (trans.), A General Introduction to Psychoanalysis (1920), 246-247.

I am curious in a super-apish way. I like finding out things. That … is all that the “noble self-sacrificing devotion to truth” of 99-44/100% of all scientists amounts to—simple curiosity. That is the spirit in which nearly all productive scientific research is carried on.

I beg this committee to recognize that knowledge is not simply another commodity. On the contrary. Knowledge is never used up, it increases by diffusion, and grows by dispersion. Knowledge and information cannot be quantitatively assessed, as a percentage of the G.N.P. Any willful cut in our resources of knowledge is an act of self-destruction.

I consider then, that generally speaking, to render a reason of an effect or Phaenomenon, is to deduce It from something else in Nature more known than it self, and that consequently there may be divers kinds of Degrees of Explication of the same thing. For although such Explications be the most satisfactory to the Understanding, wherein 'tis shewn how the effect is produc'd by the more primitive and Catholick Affection of Matter, namely bulk, shape and motion, yet are not these Explications to be despis'd, wherein particular effects are deduc'd from the more obvious and familiar Qualities or States of Bodies, ... For in the search after Natural Causes, every new measure of Discovery does both instinct and gratifie the Understanding.

I do not maintain that the chief value of the study of arithmetic consists in the lessons of morality that arise from this study. I claim only that, to be impressed from day to day, that there is something that is right as an answer to the questions with which one is able to grapple, and that there is a wrong answer—that there are ways in which the right answer can be established as right, that these ways automatically reject error and slovenliness, and that the learner is able himself to manipulate these ways and to arrive at the establishment of the true as opposed to the untrue, this relentless hewing to the line and stopping at the line, must color distinctly the thought life of the pupil with more than a tinge of morality. … To be neighborly with truth, to feel one’s self somewhat facile in ways of recognizing and establishing what is right, what is correct, to find the wrong persistently and unfailingly rejected as of no value, to feel that one can apply these ways for himself, that one can think and work independently, have a real, a positive, and a purifying effect upon moral character. They are the quiet, steady undertones of the work that always appeal to the learner for the sanction of his best judgment, and these are the really significant matters in school work. It is not the noise and bluster, not even the dramatics or the polemics from the teacher’s desk, that abide longest and leave the deepest and stablest imprint upon character. It is these still, small voices that speak unmistakably for the right and against the wrong and the erroneous that really form human character. When the school subjects are arranged on the basis of the degree to which they contribute to the moral upbuilding of human character good arithmetic will be well up the list.

I don't know what your Company is feeling as of today about the work of Dr. Alice Hamilton on benzol [benzene] poisoning. I know that back in the old days some of your boys used to think that she was a plain nuisance and just picking on you for luck. But I have a hunch that as you have learned more about the subject, men like your good self have grown to realize the debt that society owes her for her crusade. I am pretty sure that she has saved the lives of a great many girls in can-making plants and I would hate to think that you didn't agree with me.

I have a peculiar theory about radium, and I believe it is the correct one. I believe that there is some mysterious ray pervading the universe that is fluorescing to it. In other words, that all its energy is not self-constructed but that there is a mysterious something in the atmosphere that scientists have not found that is drawing out those infinitesimal atoms and distributing them forcefully and indestructibly.

I know of scarcely anything so apt to impress the imagination as the wonderful form of cosmic order expressed by the “Law of Frequency of Error.” The law would have been personified by the Greeks and deified, if they had known of it. It reigns with serenity and in complete self-effacement, amidst the wildest confusion. The huger the mob, and the greater the apparent anarchy, the more perfect is its sway. It is the supreme law of Unreason. Whenever a large sample of chaotic elements are taken in hand and marshaled in the order of their magnitude, an unsuspected and most beautiful form of regularity proves to have been latent all along.

I was suffering from a sharp attack of intermittent fever, and every day during the cold and succeeding hot fits had to lie down for several hours, during which time I had nothing to do but to think over any subjects then particularly interesting me. One day something brought to my recollection Malthus's 'Principles of Population', which I had read about twelve years before. I thought of his clear exposition of 'the positive checks to increase'—disease, accidents, war, and famine—which keep down the population of savage races to so much lower an average than that of more civilized peoples. It then occurred to me that these causes or their equivalents are continually acting in the case of animals also; and as animals usually breed much more rapidly than does mankind, the destruction every year from these causes must be enormous in order to keep down the numbers of each species, since they evidently do not increase regularly from year to year, as otherwise the world would long ago have been densely crowded with those that breed most quickly. Vaguely thinking over the enormous and constant destruction which this implied, it occurred to me to ask the question, Why do some die and some live? The answer was clearly, that on the whole the best fitted live. From the effects of disease the most healthy escaped; from enemies, the strongest, swiftest, or the most cunning; from famine, the best hunters or those with the best digestion; and so on. Then it suddenly flashed upon me that this self-acting process would necessarily improve the race, because in every generation the inferior would inevitably be killed off and the superior would remain—that is, the fittest would survive.[The phrase 'survival of the fittest,' suggested by the writings of Thomas Robert Malthus, was expressed in those words by Herbert Spencer in 1865. Wallace saw the term in correspondence from Charles Darwin the following year, 1866. However, Wallace did not publish anything on his use of the expression until very much later, and his recollection is likely flawed.]

I will simply express my strong belief, that that point of self-education which consists in teaching the mind to resist its desires and inclinations, until they are proved to be right, is the most important of all, not only in things of natural philosophy, but in every department of dally life.

I've always felt that maybe one of the reasons that I did well as a student and made such good grades was because I lacked ... self-confidence, and I never felt that I was prepared to take an examination, and I had to study a little bit extra. So that sort of lack of confidence helped me, I think, to make a good record when I was a student.

Iconography becomes even more revealing when processes or concepts, rather than objects, must be depicted–for the constraint of a definite ‘thing’ cedes directly to the imagination. How can we draw ‘evolution’ or ‘social organization,’ not to mention the more mundane ‘digestion’ or ‘self-interest,’ without portraying more of a mental structure than a physical reality? If we wish to trace the history of ideas, iconography becomes a candid camera trained upon the scholar’s mind.

Ideologues of all persuasions think they know how the economy will respond to the Administration’s strange mixture of Lafferism and monetarism. Indeed, their self-confidence is so vast, and their ability to rationalize so crafty, that one cannot imagine a scenario for the next few years, that they would regard as falsifying their dogma. The failure of any prediction can always be blamed on quirky political decisions or unforeseen historical events.

If and when all the laws governing physical phenomena are finally discovered, and all the empirical constants occurring in these laws are finally expressed through the four independent basic constants, we will be able to say that physical science has reached its end, that no excitement is left in further explorations, and that all that remains to a physicist is either tedious work on minor details or the self-educational study and adoration of the magnificence of the completed system. At that stage physical science will enter from the epoch of Columbus and Magellan into the epoch of the National Geographic Magazine!

If in a discussion of many matters … we are not able to give perfectly exact and self-consistent accounts, do not be surprised: rather we would be content if we provide accounts that are second to none in probability.

If in a given community unchecked popular rule means unlimited waste and destruction of the natural resources—soil, fertility, waterpower, forests, game, wild-life generally—which by right belong as much to subsequent generations as to the present generation, then it is sure proof that the present generation is not yet really fit for self-control, that it is not yet really fit to exercise the high and responsible privilege of a rule which shall be both by the people and for the people. The term “for the people” must always include the people unborn as well as the people now alive, or the democratic ideal is not realized.

If in some madhouse there is a lunatic who still believes the old churchly tenet that heaven is up above, even this [the first manned landing on the moon] probably will not disabuse him. Surely those of us still sane enough to be at large realize that this event will have no more to so with theology, God, or self-knowledge than any flower we pluck or any hand we press—in fact, much less.

If one looks with a cold eye at the mess man has made of history, it is difficult to avoid the conclusion that he has been afflicted by some built-in mental disorder which drives him towards self-destruction.

If one small and odd lineage of fishes had not evolved fins capable of bearing weight on land (though evolved for different reasons in lakes and seas,) terrestrial vertebrates would never have arisen. If a large extraterrestrial object—the ultimate random bolt from the blue—had not triggered the extinction of dinosaurs 65 million years ago, mammals would still be small creatures, confined to the nooks and crannies of a dinosaur's world, and incapable of evolving the larger size that brains big enough for self-consciousness require. If a small and tenuous population of protohumans had not survived a hundred slings and arrows of outrageous fortune (and potential extinction) on the savannas of Africa, then Homo sapiens would never have emerged to spread throughout the globe. We are glorious accidents of an unpredictable process with no drive to complexity, not the expected results of evolutionary principles that yearn to produce a creature capable of understanding the mode of its own necessary construction.

If there is a lesson in our story it is that the manipulation, according to strictly self-consistent rules, of a set of symbols representing one single aspect of the phenomena may produce correct, verifiable predictions, and yet completely ignore all other aspects whose ensemble constitutes reality.

If there is one thing I’ve learned in my years on this planet, it’s that the happiest and most fulfilled people I’ve known are those who devoted themselves to something bigger and more profound than merely their own self interest.

If you look at a tree and think of it as a design assignment, it would be like asking you to make something that makes oxygen, sequesters carbon, fixes nitrogen, distills water, provides habitat for hundreds of species, accrues solar energy’s fuel, makes complex sugars and food, changes colors with the seasons, creates microclimates, and self-replicates.

In acute diseases the physician must conduct his inquiries in the following way. First he must examine the face of the patient, and see whether it is like the faces of healthy people, and especially whether it is like its usual self. Such likeness will be the best sign, and the greatest unlikeness will be the most dangerous sign. The latter will be as follows. Nose sharp, eyes hollow, temples sunken, ears cold and contracted with their lobes turned outwards, the skin about the face hard and tense and parched, the colour of the face as a whole being yellow or black.

In an age of egoism, it is so difficult to persuade man that of all studies, the most important is that of himself. This is because egoism, like all passions, is blind. The attention of the egoist is directed to the immediate needs of which his senses give notice, and cannot be raised to those reflective needs that reason discloses to us; his aim is satisfaction, not perfection. He considers only his individual self; his species is nothing to him. Perhaps he fears that in penetrating the mysteries of his being he will ensure his own abasement, blush at his discoveries, and meet his conscience. True philosophy, always at one with moral science, tells a different tale. The source of useful illumination, we are told, is that of lasting content, is in ourselves. Our insight depends above all on the state of our faculties; but how can we bring our faculties to perfection if we do not know their nature and their laws! The elements of happiness are the moral sentiments; but how can we develop these sentiments without considering the principle of our affections, and the means of directing them? We become better by studying ourselves; the man who thoroughly knows himself is the wise man. Such reflection on the nature of his being brings a man to a better awareness of all the bonds that unite us to our fellows, to the re-discovery at the inner root of his existence of that identity of common life actuating us all, to feeling the full force of that fine maxim of the ancients: 'I am a man, and nothing human is alien to me.'

In both social and natural sciences, the body of positive knowledge grows by the failure of a tentative hypothesis to predict phenomena the hypothesis professes to explain; by the patching up of that hypothesis until someone suggests a new hypothesis that more elegantly or simply embodies the troublesome phenomena, and so on ad infinitum. In both, experiment is sometimes possible, sometimes not (witness meteorology). In both, no experiment is ever completely controlled, and experience often offers evidence that is the equivalent of controlled experiment. In both, there is no way to have a self-contained closed system or to avoid interaction between the observer and the observed. The Gödel theorem in mathematics, the Heisenberg uncertainty principle in physics, the self-fulfilling or self-defeating prophecy in the social sciences all exemplify these limitations.

In its earliest development knowledge is self-sown. Impressions force themselves upon men’s senses whether they will or not, and often against their will. The amount of interest in which these impressions awaken is determined by the coarser pains and pleasures which they carry in their train or by mere curiosity; and reason deals with the materials supplied to it as far as that interest carries it, and no further. Such common knowledge is rather brought than sought; and such ratiocination is little more than the working of a blind intellectual instinct. It is only when the mind passes beyond this condition that it begins to evolve science. When simple curiosity passes into the love of knowledge as such, and the gratification of the æsthetic sense of the beauty of completeness and accuracy seems more desirable that the easy indolence of ignorance; when the finding out of the causes of things becomes a source of joy, and he is accounted happy who is successful in the search, common knowledge passes into what our forefathers called natural history, whence there is but a step to that which used to be termed natural philosophy, and now passes by the name of physical science.In this final state of knowledge the phenomena of nature are regarded as one continuous series of causes and effects; and the ultimate object of science is to trace out that series, from the term which is nearest to us, to that which is at the farthest limit accessible to our means of investigation.The course of nature as it is, as it has been, and as it will be, is the object of scientific inquiry; whatever lies beyond, above, or below this is outside science. But the philosopher need not despair at the limitation on his field of labor; in relation to the human mind Nature is boundless; and, though nowhere inaccessible, she is everywhere unfathomable.

In many cases, mathematics is an escape from reality. The mathematician finds his own monastic niche and happiness in pursuits that are disconnected from external affairs. Some practice it as if using a drug. Chess sometimes plays a similar role. In their unhappiness over the events of this world, some immerse themselves in a kind of self-sufficiency in mathematics. (Some have engaged in it for this reason alone.)

In order to form for one's self a just notion of the operations which result in the production of thought, it is necessary to conceive of the brain as a peculiar organ, specially designed for the production thereof, just as the stomach is designed to effect digestion, the liver to filter the bile, the parotids and the maxillary and sublingual glands to prepare the salivary juices.

In recent years scientists have grown self-conscious, perhaps because they have only lately become of age. They realize that they are now part of the drama of human history, and they look to the professional historian for background and perspective.

In science it is no crime to be wrong, unless you are (inappropriately) laying claim to truth. What matters is that science as a whole is a self-correcting mechanism in which both new and old notions are constantly under scrutiny. In other words, the edifice of scientific knowledge consists simply of a body of observations and ideas that have (so far) proven resistant to attack, and that are thus accepted as working hypotheses about nature.

In science, self-satisfaction is death. Personal self-satisfaction is the death of the scientist. Collective self-satisfaction is the death of the research. It is restlessness, anxiety, dissatisfaction, agony of mind that nourish science.

Quoted in 'Ariadne', New Scientist (17 Jun 1976) 70, 680, which states it comes from Le Nouvel Observateur which revived the quote, “from an earlier interview.” If you know this primary source, please contact Webmaster.

In the beginning was the myth. God, in his search for self-expression, invested the souls of Hindus, Greeks, and Germans with poetic shapes and continues to invest each child’s soul with poetry every day.

In the course of centuries the naïve self-love of men has had to submit to two major blows at the hands of science. The first was when they learnt that our earth was not the centre of the universe but only a tiny fragment of a cosmic system of scarcely imaginable vastness... the second blow fell when biological research destroyed man's supposedly privileged place in creation and proved his descent from the animal kingdom and his ineradicable animal nature… But human megalomania will have suffered its third and most wounding blow from the psychological research of the present time which seeks to prove to the ego that it is not even master in its own house, but must content itself with scanty information of what is going on unconsciously in its mind.

In the year 1692, James Bernoulli, discussing the logarithmic spiral [or equiangular spiral, ρ = αθ] … shows that it reproduces itself in its evolute, its involute, and its caustics of both reflection and refraction, and then adds: “But since this marvellous spiral, by such a singular and wonderful peculiarity, pleases me so much that I can scarce be satisfied with thinking about it, I have thought that it might not be inelegantly used for a symbolic representation of various matters. For since it always produces a spiral similar to itself, indeed precisely the same spiral, however it may be involved or evolved, or reflected or refracted, it may be taken as an emblem of a progeny always in all things like the parent, simillima filia matri. Or, if it is not forbidden to compare a theorem of eternal truth to the mysteries of our faith, it may be taken as an emblem of the eternal generation of the Son, who as an image of the Father, emanating from him, as light from light, remains ὁμοούσιος with him, howsoever overshadowed. Or, if you prefer, since our spira mirabilis remains, amid all changes, most persistently itself, and exactly the same as ever, it may be used as a symbol, either of fortitude and constancy in adversity, or, of the human body, which after all its changes, even after death, will be restored to its exact and perfect self, so that, indeed, if the fashion of Archimedes were allowed in these days, I should gladly have my tombstone bear this spiral, with the motto, ‘Though changed, I arise again exactly the same, Eadem numero mutata resurgo.’”

Included in this ‘almost nothing,’ as a kind of geological afterthought of the last few million years, is the first development of self-conscious intelligence on this planet–an odd and unpredictable invention of a little twig on the mammalian evolutionary bush. Any definition of this uniqueness, embedded as it is in our possession of language, must involve our ability to frame the world as stories and to transmit these tales to others. If our propensity to grasps nature as story has distorted our perceptions, I shall accept this limit of mentality upon knowledge, for we receive in trade both the joys of literature and the core of our being.

It is admitted by all that a finished or even a competent reasoner is not the work of nature alone; the experience of every day makes it evident that education develops faculties which would otherwise never have manifested their existence. It is, therefore, as necessary to learn to reason before we can expect to be able to reason, as it is to learn to swim or fence, in order to attain either of those arts. Now, something must be reasoned upon, it matters not much what it is, provided it can be reasoned upon with certainty. The properties of mind or matter, or the study of languages, mathematics, or natural history, may be chosen for this purpose. Now of all these, it is desirable to choose the one which admits of the reasoning being verified, that is, in which we can find out by other means, such as measurement and ocular demonstration of all sorts, whether the results are true or not. When the guiding property of the loadstone was first ascertained, and it was necessary to learn how to use this new discovery, and to find out how far it might be relied on, it would have been thought advisable to make many passages between ports that were well known before attempting a voyage of discovery. So it is with our reasoning faculties: it is desirable that their powers should be exerted upon objects of such a nature, that we can tell by other means whether the results which we obtain are true or false, and this before it is safe to trust entirely to reason. Now the mathematics are peculiarly well adapted for this purpose, on the following grounds:1. Every term is distinctly explained, and has but one meaning, and it is rarely that two words are employed to mean the same thing.2. The first principles are self-evident, and, though derived from observation, do not require more of it than has been made by children in general.3. The demonstration is strictly logical, taking nothing for granted except self-evident first principles, resting nothing upon probability, and entirely independent of authority and opinion.4. When the conclusion is obtained by reasoning, its truth or falsehood can be ascertained, in geometry by actual measurement, in algebra by common arithmetical calculation. This gives confidence, and is absolutely necessary, if, as was said before, reason is not to be the instructor, but the pupil.5. There are no words whose meanings are so much alike that the ideas which they stand for may be confounded. Between the meaning of terms there is no distinction, except a total distinction, and all adjectives and adverbs expressing difference of degrees are avoided.

It is easy for men to give advice, but difficult for one’s self to follow; we have an example in physicians: for their patients they order a strict regime, for themselves, on going to bed, they do all that they have forbidden to others.

It is grindingly, creakingly, crashingly obvious that, if Darwinism were really a theory of chance, it couldn’t work. You don't need to be a mathematician or physicist to calculate that an eye or a haemoglobin molecule would take from here to infinity to self-assemble by sheer higgledy-piggledy luck. Far from being a difficulty peculiar to Darwinism, the astronomic improbability of eyes and knees, enzymes and elbow joints and all the other living wonders is precisely the problem that any theory of life must solve, and that Darwinism uniquely does solve. It solves it by breaking the improbability up into small, manageable parts, smearing out the luck needed, going round the back of Mount Improbable and crawling up the gentle slopes, inch by million-year inch. Only God would essay the mad task of leaping up the precipice in a single bound.

It is impossible to answer your question briefly; and I am not sure that I could do so, even if I wrote at some length. But I may say that the impossibility of conceiving that this grand and wondrous universe, with our conscious selves, arose through chance, seems to me the chief argument for the existence of God; but whether this is an argument of real value, I have never been able to decide.[Replying to query about his religious views]

It is interesting to transport one’s self back to the times when Astronomy began; to observe how discoveries were connected together, how errors have got mixed up with truth, have delayed the knowledge of it, and retarded its progress; and, after having followed the various epochs and traversed every climate, finally to contemplate the edifice founded on the labours of successive centuries and of various nations.

Description of Bailly’s plan when writing his history of astronomy books, quoted by François Arago, trans. by William Henry Smyth, Baden Powell and Robert Grant, in 'Bailly', Biographies of Distinguished Scientific Men (1859), Vol. 1, 114. Arago first presented this biography of Bailly when he read it to the Academy of Sciences (26 Feb 1844).

It is true that mathematics, owing to the fact that its whole content is built up by means of purely logical deduction from a small number of universally comprehended principles, has not unfittingly been designated as the science of the self-evident [Selbstverständlichen]. Experience however, shows that for the majority of the cultured, even of scientists, mathematics remains the science of the incomprehensible [Unverständlichen].

It is, I believe, justifiable to make the generalization that anything an organic chemist can synthesize can be made without him. All he does is increase the probability that given reactions will “go”. So it is quite reasonable to assume that given sufficient time and proper conditions, nucleotides, amino acids, proteins, and nucleic acids will arise by reactions that, though less probable, are as inevitable as those by which the organic chemist fulfills his predictions. So why not self-duplicating virus-like systems capable of further evolution?

It seems plain and self-evident, yet it needs to be said: the isolated knowledge obtained by a group of specialists in a narrow field has in itself no value whatsoever, but only in its synthesis with all the rest of knowledge and only inasmuch as it really contributes in this synthesis toward answering the demand, ‘Who are we?’

It seems to me it [hands-on experience] was more prevalent in a more primitive society, where you’re closer to machinery. [As a university teacher,] I see this with farm kids all the time. They have a more or less rugged self-reliance.

About the his concern that as society is changing, education is losing the benefits of childhood hand-on experience. In interview, Rushworth M. Kidder, 'Grounded in Space Science', Christian Science Monitor (22 Dec 1989).

It seems to me that the view toward which we are tending is that the specificity in gene action is always a chemical specificity, probably the production of enzymes which guide metabolic processes along particular channels. A given array of genes thus determines the production of a particular kind of protoplasm with particular properties—such, for example, as that of responding to surface forces by the formation of a special sort of semipermeable membrane, and that of responding to trivial asymmetries in the play of external stimuli by polarization, with consequent orderly quantitative gradients in all physiologic processes. Different genes may now be called into play at different points in this simple pattern, either through the local formation of their specific substrates for action, or by activation of a mutational nature. In either case the pattern becomes more complex and qualitatively differentiated. Successive interactions of differentiated regions and the calling into play of additional genes may lead to any degree of complexity of pattern in the organism as a largely self-contained system. The array of genes, assembled in the course of evolution, must of course be one which determines a highly self­regulatory system of reactions. On this view the genes are highly specific chemically, and thus called into play only under very specific conditions; but their morphological effects, if any, rest on quantitative influences of immediate or remote products on growth gradients, which are resultants of all that has gone on before in the organism.

It was astonishing that for some considerable distance around the mould growth the staphococcal colonies were undergoing lysis. What had formerly been a well-grown colony was now a faint shadow of its former self...I was sufficiently interested to pursue the subject.[Sep 1928, the first observation of penicillin. Lysis is the dissolution or destruction of cells.]

From Novum Organum (1620), Book 1, Aphorism 6. Translated as The New Organon: Aphorisms Concerning the Interpretation of Nature and the Kingdom of Man), collected in James Spedding, Robert Ellis and Douglas Heath (eds.), The Works of Francis Bacon (1857), Vol. 4, 48.

It would not become physical science to see in its self created, changeable, economical tools, molecules and atoms, realities behind phenomena... The atom must remain a tool for representing phenomena.

I’m very intense in my work. At any given moment, I think I know the answer to some problem, and that I’m right. Since science is the only self-correcting human institution I know of, you should not be frightened to take an extreme stand, if that causes the stand to be examined more thoroughly than it might be if you are circumspect. I’ve always been positive about the value of the Hubble constant, knowing full well that it probably isn’t solved.

Leaving aside genetic surgery applied humans, I foresee that the coming century will place in our hands two other forms of biological technology which are less dangerous but still revolutionary enough to transform the conditions of our existence. I count these new technologies as powerful allies in the attack on Bernal's three enemies. I give them the names “biological engineering” and “self-reproducing machinery.” Biological engineering means the artificial synthesis of living organisms designed to fulfil human purposes. Self-reproducing machinery means the imitation of the function and reproduction of a living organism with non-living materials, a computer-program imitating the function of DNA and a miniature factory imitating the functions of protein molecules. After we have attained a complete understanding of the principles of organization and development of a simple multicellular organism, both of these avenues of technological exploitation should be open to us.

From 3rd J.D. Bernal Lecture, Birkbeck College London (16 May 1972), The World, the Flesh and the Devil (1972), 6. Collected in The Scientist as Rebel (2006), 292. (The World, the Flesh & the Devil: An Enquiry into the Future of the Three Enemies of the Rational Soul is the title of a book by J. D Bernal, a scientist who pioneered X-ray crystallography.)

Let us now declare the means whereby our understanding can rise to knowledge without fear of error. There are two such means: intuition and deduction. By intuition I mean not the varying testimony of the senses, nor the deductive judgment of imagination naturally extravagant, but the conception of an attentive mind so distinct and so clear that no doubt remains to it with regard to that which it comprehends; or, what amounts to the same thing, the self-evidencing conception of a sound and attentive mind, a conception which springs from the light of reason alone, and is more certain, because more simple, than deduction itself. … It may perhaps be asked why to intuition we add this other mode of knowing, by deduction, that is to say, the process which, from something of which we have certain knowledge, draws consequences which necessarily follow therefrom. But we are obliged to admit this second step; for there are a great many things which, without being evident of themselves, nevertheless bear the marks of certainty if only they are deduced from true and incontestable principles by a continuous and uninterrupted movement of thought, with distinct intuition of each thing; just as we know that the last link of a long chain holds to the first, although we can not take in with one glance of the eye the intermediate links, provided that, after having run over them in succession, we can recall them all, each as being joined to its fellows, from the first up to the last. Thus we distinguish intuition from deduction, inasmuch as in the latter case there is conceived a certain progress or succession, while it is not so in the former; … whence it follows that primary propositions, derived immediately from principles, may be said to be known, according to the way we view them, now by intuition, now by deduction; although the principles themselves can be known only by intuition, the remote consequences only by deduction.

Let us then suppose the Mind to be, as we say, white Paper, void of all Characters, without any Ideas; How comes it to be furnished? Whence comes it by that vast store, which the busy and boundless Fancy of Man has painted on it, with an almost endless variety? Whence has it all the materials of Reason and Knowledge? To this I answer, in one word, from Experience: In that, all our Knowledge is founded; and from that it ultimately derives it self. Our Observation employ’d either about external, sensible Objects; or about the internal Operations of our Minds, perceived and reflected on by our selves, is that, which supplies our Understandings with all the materials of thinking.

Man has never been a particularly modest or self-deprecatory animal, and physical theory bears witness to this no less than many other important activities. The idea that thought is the measure of all things, that there is such a thing as utter logical rigor, that conclusions can be drawn endowed with an inescapable necessity, that mathematics has an absolute validity and controls experience—these are not the ideas of a modest animal. Not only do our theories betray these somewhat bumptious traits of self-appreciation, but especially obvious through them all is the thread of incorrigible optimism so characteristic of human beings.

Mathematical reasoning is deductive in the sense that it is based upon definitions which, as far as the validity of the reasoning is concerned (apart from any existential import), needs only the test of self-consistency. Thus no external verification of definitions is required in mathematics, as long as it is considered merely as mathematics.

Mathematics … above all other subjects, makes the student lust after knowledge, fills him, as it were, with a longing to fathom the cause of things and to employ his own powers independently; it collects his mental forces and concentrates them on a single point and thus awakens the spirit of individual inquiry, self-confidence and the joy of doing; it fascinates because of the view-points which it offers and creates certainty and assurance, owing to the universal validity of its methods. Thus, both what he receives and what he himself contributes toward the proper conception and solution of a problem, combine to mature the student and to make him skillful, to lead him away from the surface of things and to exercise him in the perception of their essence. A student thus prepared thirsts after knowledge and is ready for the university and its sciences. Thus it appears, that higher mathematics is the best guide to philosophy and to the philosophic conception of the world (considered as a self-contained whole) and of one’s own being.

Mathematics … engages, it fructifies, it quickens, compels attention, is as circumspect as inventive, induces courage and self-confidence as well as modesty and submission to truth. It yields the essence and kernel of all things, is brief in form and overflows with its wealth of content. It discloses the depth and breadth of the law and spiritual element behind the surface of phenomena; it impels from point to point and carries within itself the incentive toward progress; it stimulates the artistic perception, good taste in judgment and execution, as well as the scientific comprehension of things.

Mathematics, as much as music or any other art, is one of the means by which we rise to a complete self-consciousness. The significance of mathematics resides precisely in the fact that it is an art; by informing us of the nature of our own minds it informs us of much that depends on our minds.

Mathematics, including not merely Arithmetic, Algebra, Geometry, and the higher Calculus, but also the applied Mathematics of Natural Philosophy, has a marked and peculiar method or character; it is by preeminence deductive or demonstrative, and exhibits in a
nearly perfect form all the machinery belonging to this mode of obtaining truth. Laying down a very small number of first principles, either self-evident or requiring very little effort to prove them, it evolves a vast number of deductive truths and applications, by a procedure in the highest degree mathematical and systematic.

Measured objectively, what a man can wrest from Truth by passionate striving is utterly infinitesimal. But the striving frees us from the bonds of the self and makes us comrades of those who are the best and the greatest.

Modern anthropology has taught us, through comparative investigation of so-called primitive cultures, that the social behavior of human beings may differ greatly, depending upon prevailing cultural patterns and the types of organisation which predominate in society. It is on this that those who are striving to improve the lot of man may ground their hopes: human beings are not condemned, because of their biological constitution, to annihilate each other or to be at the mercy of a cruel, self-inflicted fate.

Nature never makes excellent things, for mean or no uses: and it is hardly to be conceived, that our infinitely wise Creator, should make so admirable a Faculty, as the power of Thinking, that Faculty which comes nearest the Excellency of his own incomprehensible Being, to be so idlely and uselesly employ’d, at least 1/4 part of its time here, as to think constantly, without remembering any of those Thoughts, without doing any good to it self or others, or being anyway useful to any other part of Creation.

Nature when more shy in one, hath more freely confest and shewn herself in another; and a Fly sometimes hath given greater light towards the true knowledge of the structure and the uses of the Parts in Humane Bodies, than an often repeated dissection of the same might have done … We must not therefore think the meanest of the Creation vile or useless, since that in them in lively Characters (if we can but read) we may find the knowledge of a Deity and ourselves … In every Animal there is a world of wonders; each is a Microcosme or a world in it self.

Observation is simple, indefatigable, industrious, upright, without any preconceived opinion. Experiment is artificial, impatient, busy, digressive; passionate, unreliable. We see every day one experiment after another, the second outweighing the impression gained from the first, both, often enough, carried out by men who are neither much distinguished for their spirit, nor for carrying with them the truth of personality and self denial. Nothing is easier than to make a series of so-called interesting experiments. Nature can only in some way be forced, and in her distress, she will give her suffering answer. Nothing is more difficult than to explain it, nothing is more difficult than a valid physiological experiment. We consider as the first task of current physiology to point at it and comprehend it.

Our posturing, our imagined self-importance, the delusion that we have some privileged position in the Universe, are challenged by this point of pale light. Our planet is a lonely speck in the great enveloping cosmic dark. In our obscurity, in all this vastness, there is no hint that help will come from elsewhere to save us from ourselves.

Out of the interaction of form and content in mathematics grows an acquaintance with methods which enable the student to produce independently within certain though moderate limits, and to extend his knowledge through his own reflection. The deepening of the consciousness of the intellectual powers connected with this kind of activity, and the gradual awakening of the feeling of intellectual self-reliance may well be considered as the most beautiful and highest result of mathematical training.

Physio-philosophy has to show how, and in accordance indeed with what laws, the Material took its origin; and, therefore, how something derived its existence from nothing. It has to portray the first periods of the world's development from nothing; how the elements and heavenly bodies originated; in what method by self-evolution into higher and manifold forms, they separated into minerals, became finally organic, and in Man attained self-consciousness.

Politicians, real-estate agents, used-car salesmen, and advertising copy-writers are expected to stretch facts in self-serving directions, but scientists who falsify their results are regarded by their peers as committing an inexcusable crime. Yet the sad fact is that the history of science swarms with cases of outright fakery and instances of scientists who unconsciously distorted their work by seeing it through lenses of passionately held beliefs.

Politicians, real-estate agents, used-car salesmen, and advertising copy-writers are expected to stretch facts in self-serving directions, but scientists who falsify their results are regarded by their peers as committing an inexcusable crime. Yet the sad fact is that the history of science swarms with cases of outright fakery and instances of scientists who unconsciously distorted their work by seeing it through lenses of passionately held beliefs.

Pride is a sense of worth derived from something that is not organically part of us, while self-esteem derives from the potentialities and achievements of the self. We are proud when we identify ourselves with an imaginary self, a leader, a holy cause, a collective body or possessions. There is fear and intolerance in pride; it is sensitive and uncompromising. The less promise and potency in the self, the more imperative is the need for pride. The core of pride is self-rejection.

Probably among all the pursuits of the University, mathematics pre-eminently demand self-denial, patience, and perseverance from youth, precisely at that period when they have liberty to act for themselves, and when on account of obvious temptations, habits of restraint and application are peculiarly valuable.

Psychiatrist David Shainberg argued that mental illness, which appears chaotic, is actually the reverse. Mental illness occurs when images of the self become rigid and closed, restricting an open creative response to the world.[Co-author with David Peat]

In John F. Briggs and David Peat, Seven Life Lessons of Chaos: Spiritual Wisdom from the Science of Change (1999, 2000), 29. A footnote gives the source of this idea as from David Shainberg, The Transforming Self: New Dimensions in Psychoanalytic Process (1973).

Pure mathematics is a collection of hypothetical, deductive theories, each consisting of a definite system of primitive, undefined, concepts or symbols and primitive, unproved, but self-consistent assumptions (commonly called axioms) together with their logically deducible consequences following by rigidly deductive processes without appeal to intuition.

Rulers and generals muster their troops. Magnates muster the sums of money which give them power. The fascist dictators muster the irrational human reactions which make it possible for them to attain and maintain their power over the masses. The scientists muster knowledge and means of research. But, thus far, no organization fighting for freedom has ever mustered the biological arsenal where the weapons are to be found for the establishment and the maintenance of human freedom. All precision of our social existence notwithstanding, there is as yet no definition of the word freedom which would be in keeping with natural science. No word is more misused and misunderstood. To define freedom is the same as to define sexual health. But nobody will openly admit this. The advocacy of personal and social freedom is connected with anxiety and guilt feelings. As if to be free were a sin or at least not quite as it should be. Sex-economy makes this guilt feeling comprehensible: freedom without sexual self-determination is in itself a contradiction. But to be sexual means—according to the prevailing human structure—to be sinful or guilty. There are very few people who experience sexual love without guilt feeling. “Free love” has acquired a degrading meaning: it lost the meaning given it by the old fighters for freedom. In films and in books, to be genital and to be criminal are presented as the same thing.

Science is but a feeble means for motivating life. It enlightens men, but fails to arouse them to deeds of self-sacrifice and devotion. … It dispels ignorance, but it never launched a crusade. It gives aid in the struggle with the hard surroundings of life, but it does not inform us to what end we struggle, or whether the struggle is worth while. … Intelligence can do little more than direct.

As quoted by M.G. Mellon in his retiring Presidential Address to the Winter Meeting of the Indiana Academy of Science at the University of Notre Dame (30 Oct 1942), 'Science, Scientists, and Society', printed in Proceedings of the Indiana Academy of Science (1943), 52, 15. No source citation given.

Science itself is badly in need of integration and unification. The tendency is more and more the other way ... Only the graduate student, poor beast of burden that he is, can be expected to know a little of each. As the number of physicists increases, each specialty becomes more self-sustaining and self-contained. Such Balkanization carries physics, and indeed, every science further away, from natural philosophy, which, intellectually, is the meaning and goal of science.

Science will continue to surprise us with what it discovers and creates; then it will astound us by devising new methods to surprise us. At the core of science’s self-modification is technology. New tools enable new structures of knowledge and new ways of discovery. The achievement of science is to know new things; the evolution of science is to know them in new ways. What evolves is less the body of what we know and more the nature of our knowing.

Scientific modes of thought cannot be developed and become generally accepted unless people renounce their primary, unreflecting, and spontaneous attempt to understand all their experience in terms of its purpose and meaning for themselves. The development that led to more adequate knowledge and increasing control of nature was therefore, considered from one aspect, also a development toward greater self-control by men.

The Civilizing Process: The Development of Manners—Changes in the Code of Conduct and Feeling in Early Modern Times (1939), trans. Edmund Jephcott (1978), 225. Originally published as Über den Prozess der Zivilisation.

Scientific training gives its votaries freedom from the impositions of modern quackery. Those who know nothing of the laws and processes of Nature fall an easy prey to quacks and impostors. Perfectionism in the realm of religion; a score of frauds in the realm of medicine, as electric shoe soles, hair brushes and belts, electropises, oxydonors, insulating bed casters, and the like; Christian science. In the presence of whose unspeakable stillness and self-stultifying idealism a wise man knows not whether to laugh or cry; Prof. Weltmer's magnetic treatment of disease; divine healing and miracle working by long-haired peripatetics—these and a score of other contagious fads and rank impostures find their followers among those who have no scientific training. Among their deluded victims are thousands of men and women of high character, undoubted piety, good intentions, charitable impulses and literary culture, but none trained to scientific research. Vaccinate the general public with scientific training and these epidemics will become a thing of the past.

As quoted by S.D. Van Meter, Chairman, closing remarks for 'Report of Committee on Public Policy and Legislation', to the Colorado State Medical Society in Denver, printed in Colorado Medicine (Oct 1904), 1, No. 12, 363. Van Meter used the quote following his statement, “In conclusion, allow me to urge once more the necessity of education of the public as well as the profession if we ever expect to correct the evils we are striving to reach by State and Society legislation. Much can be accomplished toward this end by the publication of well edited articles in the secular press upon medical subjects the public is eager to know about.” Prof. Weitmer is presumably Sidney A. Weltmer, founder of The Weltmer Institute of Suggestive Therapeutics, who offered a Course in Magnetic Healing by mail order correspondance (1899).

Self-esteem must be earned! When you dare to dream, dare to follow that dream, dare to suffer through the pain, sacrifice, self-doubts, and friction from the world, you will genuinely impress yourself.

Since an organism is inseparable from its environment, any person who attempts to understand an organism’s distribution must keep constantly in mind that the item being studied is neither a stuffed skin, a pickled specimen, nor a dot on a map. It is not even the live organism held in the hand, caged in a laboratory, or seen in the field. It is a complex interaction between a self-sustaining physicochemical system and the environment. An obvious corollary is that to know the organism it is necessary to know its environment.

Since Copernicus, man seems to have got himself on an inclined plane—now he is slipping faster and faster away from the center into—what? into nothingness? into a 'penetrating sense of his nothingness?' ... all science, natural as well as unnatural—which is what I call the self-critique of knowledge—has at present the object of dissuading man from his former respect for himself, as if this had been but a piece of bizarre conceit.

Study the hindrances, acquaint yourself with the causes which have led up to the disease. Don’t guess at them, but know them through and through if you can; and if you do not know them, know that you do not, and still inquire. “Cannot” is a word for the idle, the indifferent, the self-satisfied, but it is not admissible in science. “I do not know” is manly if it does not stop there, but to say “I cannot” is a judgment both entirely illogical, and in itself bad as favouring rest in ignorance.

Success in the solution of a problem generally depends in a great measure on the selection of the most appropriate method of approaching it; many properties of conic sections (for instance) being demonstrable by a few steps of pure geometry which would involve the most laborious operations with trilinear co-ordinates, while other properties are almost self-evident under the method of trilinear co-ordinates, which it would perhaps be actually impossible to prove by the old geometry.

Symbolism is useful because it makes things difficult. Now in the beginning everything is self-evident, and it is hard to see whether one self-evident proposition follows from another or not. Obviousness is always the enemy to correctness. Hence we must invent a new and difficult symbolism in which nothing is obvious. … Thus the whole of Arithmetic and Algebra has been shown to require three indefinable notions and five indemonstrable propositions.

That a shutdown of existing reactors would be catastrophic I believe is self-evident. It is not only the energy that we would lose, it is the $100 billion investment whose write-off would cause a violent shock to our financial institutions.

The Qualities then that are in Bodies rightly considered, are of Three sorts.First, the Bulk, Figure, Number, Situation, and Motion, or Rest of their solid Parts; those are in them, whether we perceive them or no; and when they are of that size, that we can discover them, we have by these an Idea of the thing, as it is in it self, as is plain in artificial things. These I call primary Qualities.Secondly, The Power that is in any Body, by Reason of its insensible primary Qualities, to operate after a peculiar manner on any of our Senses, and thereby produce in us the different Ideas of several Colours, Sounds, Smells, Tastes, etc. These are usually called sensible Qualities.Thirdly, The Power that is in any Body, by Reason of the particular Constitution of its primary Qualities, to make such a change in the Bulk, Figure, Texture, and Motion of another Body, as to make it operate on our Senses, differently from what it did before. Thus the Sun has a Power to make Wax white, and Fire to make Lead fluid. These are usually called Powers.

The beauty of his better self lives onIn minds he touched with fire, in many an eyeHe trained to Truth’s exact severity;He was a teacher: why be grieved for himWhose living word still stimulates the air?

The classification of facts and the formation of absolute judgments upon the basis of this classification—judgments independent of the idiosyncrasies of the individual mind—essentially sum up the aim and method of modern science. The scientific man has above all things to strive at self-elimination in his judgments, to provide an argument which is as true for each individual mind as for his own.

The day when the scientist, no matter how devoted, may make significant progress alone and without material help is past. This fact is most self-evident in our work. Instead of an attic with a few test tubes, bits of wire and odds and ends, the attack on the atomic nucleus has required the development and construction of great instruments on an engineering scale.

The enthusiasm of Sylvester for his own work, which manifests itself here as always, indicates one of his characteristic qualities: a high degree of subjectivity in his productions and publications. Sylvester was so fully possessed by the matter which for the time being engaged his attention, that it appeared to him and was designated by him as the summit of all that is important, remarkable and full of future promise. It would excite his phantasy and power of imagination in even a greater measure than his power of reflection, so much so that he could never marshal the ability to master his subject-matter, much less to present it in an orderly manner.Considering that he was also somewhat of a poet, it will be easier to overlook the poetic flights which pervade his writing, often bombastic, sometimes furnishing apt illustrations; more damaging is the complete lack of form and orderliness of his publications and their sketchlike character, … which must be accredited at least as much to lack of objectivity as to a superfluity of ideas. Again, the text is permeated with associated emotional expressions, bizarre utterances and paradoxes and is everywhere accompanied by notes, which constitute an essential part of Sylvester’s method of presentation, embodying relations, whether proximate or remote, which momentarily suggested themselves. These notes, full of inspiration and occasional flashes of genius, are the more stimulating owing to their incompleteness. But none of his works manifest a desire to penetrate the subject from all sides and to allow it to mature; each mere surmise, conceptions which arose during publication, immature thoughts and even errors were ushered into publicity at the moment of their inception, with utmost carelessness, and always with complete unfamiliarity of the literature of the subject. Nowhere is there the least trace of self-criticism. No one can be expected to read the treatises entire, for in the form in which they are available they fail to give a clear view of the matter under contemplation.Sylvester’s was not a harmoniously gifted or well-balanced mind, but rather an instinctively active and creative mind, free from egotism. His reasoning moved in generalizations, was frequently influenced by analysis and at times was guided even by mystical numerical relations. His reasoning consists less frequently of pure intelligible conclusions than of inductions, or rather conjectures incited by individual observations and verifications. In this he was guided by an algebraic sense, developed through long occupation with processes of forms, and this led him luckily to general fundamental truths which in some instances remain veiled. His lack of system is here offset by the advantage of freedom from purely mechanical logical activity.The exponents of his essential characteristics are an intuitive talent and a faculty of invention to which we owe a series of ideas of lasting value and bearing the germs of fruitful methods. To no one more fittingly than to Sylvester can be applied one of the mottos of the Philosophic Magazine:“Admiratio generat quaestionem, quaestio investigationem investigatio inventionem.”

The explosive component in the contemporary scene is not the clamor of the masses but the self-righteous claims of a multitude of graduates from schools and universities. This army of scribes is clamoring for a society in which planning, regulation, and supervision are paramount and the prerogative of the educated. They hanker for the scribe’s golden age, for a return to something like the scribe-dominated societies of ancient Egypt, China, and Europe of the Middle Ages. There is little doubt that the present trend in the new and renovated countries toward social regimentation stems partly from the need to create adequate employment for a large number of scribes. And since the tempo of the production of the literate is continually increasing, the prospect is of ever-swelling bureaucracies.

The fact that man produces a concept ‘I’ besides the totality of his mental and emotional experiences or perceptions does not prove that there must be any specific existence behind such a concept. We are succumbing to illusions produced by our self-created language, without reaching a better understanding of anything. Most of so-called philosophy is due to this kind of fallacy.

The fateful question for the human species seems to me to be whether and to what extent their cultural development will succeed in mastering the disturbance of their communal life by the human instinct of aggression and self-destruction … One thing only do I know for certain and that is that man's judgements of value follow directly from his wihes for happiness—that, accordingly, they are an attempt to support his illusions with arguments. (1930)

The great purpose of school can be realized better in dark, airless, ugly places … It is to master the physical self, to transcend the beauty of nature. School should develop the power to withdraw from the external world.

As quoted in various 21st century books, each time cited only as from the The Philosophy of Education (1906), with no page number. For example, in John Taylor Gatto, A Different Kind of Teacher: Solving the Crisis of American Schooling (2000), 61. Note: Webmaster is suspicious of the attribution of this quote. The Library of Congress lists no such title by Harris in 1906. The LOC does catalog this title by Harris for 1893, which is a 9-page pamphlet printing the text of a series of five lectures. These lectures do not contain this quote. William Torrey Harris was editor of the International Education Series of books, of which Vol. 1 was the translation by Anna Callender Bracket of The Philosophy of Education by Johann Karl Friedrich Rosenkranz (2nd ed. rev. 1886). The translation was previously published in The Journal of Speculative Philosophy (1872, -73, -74), Vols vi-viii. Webmaster does not find the quote in that book, either. Webmaster has so far been unable to verify this quote, in these words, or even find the quote in any 19th or 20th century publication (which causes more suspicion). If you have access to the primary source for this quote, please contact Webmaster.

The greatest possibility of evil in self-medication [with penicillin] is the use of too-small doses, so that, instead of clearing up the infection, the microbes are educated to resist penicillin and a host of penicillin-fast organisms is bred out which can be passed on to other individuals and perhaps from there to others until they reach someone who gets a septicemia or a pneumonia which penicillin cannot save. In such a case the thoughtless person playing with penicillin treatment is morally responsible for the death of the man who finally succumbs to infection with the penicillin-resistant organism. I hope this evil can be averted.

The Himalayas are the crowning achievement of the Indo-Australian plate. India in the Oligocene crashed head on into Tibet, hit so hard that it not only folded and buckled the plate boundaries but also plowed into the newly created Tibetan plateau and drove the Himalayas five and a half miles into the sky. The mountains are in some trouble. India has not stopped pushing them, and they are still going up. Their height and volume are already so great they are beginning to melt in their own self-generated radioactive heat. When the climbers in 1953 planted their flags on the highest mountain, they set them in snow over the skeletons of creatures that had lived in a warm clear ocean that India, moving north, blanked out. Possibly as much as 20,000 feet below the sea floor, the skeletal remains had turned into rock. This one fact is a treatise in itself on the movements of the surface of the earth.If by some fiat, I had to restrict all this writing to one sentence; this is the one I would choose: the summit of Mount Everest is marine limestone.

The individual on his own is stable only so long as he is possessed of self-esteem. The maintenance of self-esteem is a continuous task which taxes all of the individual’s powers and inner resources. We have to prove our worth and justify our existence anew each day. When, for whatever reason, self-esteem is unattainable, the autonomous individual becomes a highly explosive entity. He turns away from an unpromising self and plunges into the pursuit of pride—the explosive substitute for self-esteem. All social disturbances and upheavals have their roots in crises of individual self-esteem, and the great endeavor in which the masses most readily unite is basically a search for pride.

The intrinsic character of mathematical research and knowledge is based essentially on three properties: first, on its conservative attitude towards the old truths and discoveries of mathematics; secondly, on its progressive mode of development, due to the incessant acquisition of new knowledge on the basis of the old; and thirdly, on its self-sufficiency and its consequent absolute independence.

In Tarner Lecture, at Trinity College, Cambridge (Oct 1956), 'The Principle of Objectivation', printed in Mind and Matter (1958), 39. Also collected in What is Life?: With Mind and Matter and Autobiographical Sketches (1992, 2012), 119.

The mathematician starts with a few propositions, the proof of which is so obvious that they are called self-evident, and the rest of his work consists of subtle deductions from them. The teaching of languages, at any rate as ordinarily practised, is of the same general nature authority and tradition furnish the data, and the mental operations are deductive.

The next care to be taken, in respect of the Senses, is a supplying of their infirmities with Instruments, and, as it were, the adding of artificial Organs to the natural; this in one of them has been of late years accomplisht with prodigious benefit to all sorts of useful knowledge, by the invention of Optical Glasses. By the means of Telescopes, there is nothing so far distant but may be represented to our view; and by the help of Microscopes, there is nothing so small, as to escape our inquiry; hence there is a new visible World discovered to the understanding. By this means the Heavens are open'd, and a vast number of new Stars, and new Motions, and new Productions appear in them, to which all the ancient Astronomers were utterly Strangers. By this the Earth it self, which lyes so neer us, under our feet, shews quite a new thing to us, and in every little particle of its matter, we now behold almost as great a variety of creatures as we were able before to reckon up on the whole Universe it self.

The old Sussex tortoise, that I have mentioned to you so often, is become my property. I dug it out of its winter dormitory in March last, when it was enough awakened to express its resentments by hissing; and, packing it in a box with earth, carried it eighty miles in post-chaises. The rattle and hurry of the journey so perfectly roused it that, when I turned it out on a border, it walked twice down to the bottom of my garden; however, in the evening, the weather being cold, it buried it-self in the loose mound, and continues still concealed … When one reflects on the state of this strange being, it is a matter of wonder to find that Providence should bestow such a profusion of days, such a seeming waste of longevity, on a reptile that appears to relish it so little as to squander more than two-thirds of its existence in joyless stupor, and be lost to all sensation for months together in the profoundest of slumbers.

The practice of that which is ethically best—what we call goodness or virtue—involves a course of conduct which, in all respects, is opposed to that which leads to success in the cosmic struggle for existence. In place of ruthless self-assertion it demands self-restraint; in place of thrusting aside, or treading down, all competitors, it requires that the individual shall not merely respect, but shall help his fellows… It repudiates the gladiatorial theory of existence… Laws and moral precepts are directed to the end of curbing the cosmic process.

The principles of logic and mathematics are true universally simply because we never allow them to be anything else. And the reason for this is that we cannot abandon them without contradicting ourselves, without sinning against the rules which govern the use of language, and so making our utterances self-stultifying. In other words, the truths of logic and mathematics are analytic propositions or tautologies.

The process of self-estrangement and its removal underlies all education. The mind must fix its attention upon what is alien to it and penetrate its disguise, making it become familiar. … Wonder is only the first stage of this estrangement. It must be followed by recognition.

The quantum theory of gravity has opened up a new possibility, in which there would be no boundary to space-time and so there would be no need to specify the behaviour at the boundary. There would be no singularities at which the laws of science broke down and no edge of space-time at which one would have to appeal to God or some new law to set the boundary conditions for space-time. One could say: 'The boundary condition of the universe is that it has no boundary.' The universe would be completely self-contained and not affected by anything outside itself. It would neither be created nor destroyed. It would just BE.

The question of the origin of life is essentially speculative. We have to construct, by straightforward thinking on the basis of very few factual observations, a plausible and self-consistent picture of a process which must have occurred before any of the forms which are known to us in the fossil record could have existed.

The reasoning of mathematicians is founded on certain and infallible principles. Every word they use conveys a determinate idea, and by accurate definitions they excite the same ideas in the mind of the reader that were in the mind of the writer. When they have defined the terms they intend to make use of, they premise a few axioms, or self-evident principles, that every one must assent to as soon as proposed. They then take for granted certain postulates, that no one can deny them, such as, that a right line may be drawn from any given point to another, and from these plain, simple principles they have raised most astonishing speculations, and proved the extent of the human mind to be more spacious and capacious than any other science.

The self is the class (not the collection) of the experiences (or autopsychological states). The self does not belong to the expression of the basic experience, but is constructed only on a very high level.

The self-fulfilling prophecy is, in the beginning, a false definition of the situation evoking a new behavior which makes the originally false conception come true. The specious validity of the self-fulfilling prophecy perpetuates a reign of error. For the prophet will cite the actual course of events as proof that he was right from the very beginning. … Such are the perversities of social logic.

The self-same atoms which, chaotically dispersed, made the nebula, now, jammed and temporarily caught in peculiar positions, form our brains; and the “evolution” of brains, if understood, would be simply the account of how the atoms came to be so caught and jammed.

The story of a theory’s failure often strikes readers as sad and unsatisfying. Since science thrives on self-correction, we who practice this most challenging of human arts do not share such a feeling. We may be unhappy if a favored hypothesis loses or chagrined if theories that we proposed prove inadequate. But refutation almost always contains positive lessons that overwhelm disappointment, even when no new and comprehensive theory has yet filled the void.

The successes of the differential equation paradigm were impressive and extensive. Many problems, including basic and important ones, led to equations that could be solved. A process of self-selection set in, whereby equations that could not be solved were automatically of less interest than those that could.

The true beauty of nature is her amplitude; she exists neither for nor because of us, and possesses a staying power that all our nuclear arsenals cannot threaten (much as we can easily destroy our puny selves).

The universe is of the nature of a thought or sensation in a universal Mind… To put the conclusion crudely—the stuff of the world is mind-stuff. As is often the way with crude statements, I shall have to explain that by “mind” I do not exactly mean mind and by “stuff” I do not at all mean stuff. Still that is about as near as we can get to the idea in a simple phrase. The mind-stuff of the world is something more general than our individual conscious minds; but we may think of its nature as not altogether foreign to feelings in our consciousness… Having granted this, the mental activity of the part of world constituting ourselves occasions no great surprise; it is known to us by direct self-knowledge, and we do not explain it away as something other than we know it to be—or rather, it knows itself to be.

The value the world sets upon motives is often grossly unjust and inaccurate. Consider, for example, two of them: mere insatiable curiosity and the desire to do good. The latter is put high above the former, and yet it is the former that moves some of the greatest men the human race has yet produced: the scientific investigators. What animates a great pathologist? Is it the desire to cure disease, to save life? Surely not, save perhaps as an afterthought. He is too intelligent, deep down in his soul, to see anything praiseworthy in such a desire. He knows by life-long observation that his discoveries will do quite as much harm as good, that a thousand scoundrels will profit to every honest man, that the folks who most deserve to be saved will probably be the last to be saved. No man of self-respect could devote himself to pathology on such terms. What actually moves him is his unquenchable curiosity–his boundless, almost pathological thirst to penetrate the unknown, to uncover the secret, to find out what has not been found out before. His prototype is not the liberator releasing slaves, the good Samaritan lifting up the fallen, but the dog sniffing tremendously at an infinite series of rat-holes.

There are many hypotheses in science which are wrong. That’s perfectly all right; they’re the aperture to finding out what’s right. Science is a self-correcting process. To be accepted, new ideas must survive the most rigorous standards of evidence and scrutiny.

There may only be a small number of laws, which are self-consistent and which lead to complicated beings like ourselves. … And even if there is only one unique set of possible laws, it is only a set of equations. What is it that breathes fire into the equations and makes a universe for them to govern? Is the ultimate unified theory so compelling that it brings about its own existence?

Therefore I chance to think that all Nature and the graceful sky are symbolised in the art of geometry. … Now as God the maker play’d He taught the game to Nature whom He created in His image; taught her the self-same game which He played to her.

These estimates may well be enhanced by one from F. Klein (1849-1925), the leading German mathematician of the last quarter of the nineteenth century. “Mathematics in general is fundamentally the science of self-evident things.” ... If mathematics is indeed the science of self-evident things, mathematicians are a phenomenally stupid lot to waste the tons of good paper they do in proving the fact. Mathematics is abstract and it is hard, and any assertion that it is simple is true only in a severely technical sense—that of the modern postulational method which, as a matter of fact, was exploited by Euclid. The assumptions from which mathematics starts are simple; the rest is not.