Death Stranding is to be the first game by Kojima Productions. It will feature actors Norman Reedus and Mads Mikkelsen, as well as Guillermo del Toro. According to the game's director Hideo Kojima Reedus and Mikkelsen are expected to give their performances to the characters they play, while the character based on del Toro's appearance will be played by a to be cast actor.

Despite Kojima saying he expected the studio's first game to be released on PC, Death Stranding is currently only announced to be released on PS4.