TY - JOUR
T1 - Household air pollution as an important factor in the complex relationship between altitude and COPD
JF - European Respiratory Journal
JO - Eur Respir J
DO - 10.1183/13993003.02454-2018
VL - 53
IS - 2
SP - 1802454
AU - Basagaña, Xavier
Y1 - 2019/02/01
UR - http://erj.ersjournals.com/content/53/2/1802454.abstract
N2 - The relationship between altitude and chronic obstructive pulmonary disease (COPD) remains controversial. Altitude per se is a relevant variable for respiratory health, as subjects living at high altitude are exposed to lower atmospheric pressure, which by affecting the driving pressure for gas exchange in the lungs leads to hypoxia [1]. It has been reported that high altitude natives have larger lungs and higher forced vital capacity (FVC) than predicted, potentially as an adaptation mechanism, which is relevant for COPD research, as it consequently leads to lower forced expiratory volume in 1 s to FVC ratios [2–4].Household air pollution, whose relationship with COPD is still understudied, is yet another factor explaining the complex relationship between altitude and COPD http://ow.ly/Ao4K30nmxDtI thank Otavio Ranzani (ISGlobal) for critical reading of the text. ISGlobal is a member of the CERCA Programme, Generalitat de Catalunya.
ER -