Rushing numbers offer the greatest disparity, and perhaps the best reflection of their NFL status. After all, the 49ers have run for at least 149 yards in each game during their four-game win streak, while the Jaguars continue to search for their first 100-yard rushing game (and first win).

The 49ers tout the NFL’s third-ranked rushing attack (143.3 yards per game) and its fourth-leading rusher (Frank Gore, 547 yards). The Jaguars average a league-worst 63.0 rushing yards per game, with Maurice Jones-Drew netting just 3.1 yards per carry (25th-ranked total of 316 yards).

Here are other stats worth noting before the 49ers return to practice Wednesday at their resort in Hertforshire:

— The Jaguars’ offense is among the league’s bottom three in most categories, including: yards, rushing yards, interception percentage, sacks, first downs, third-down efficiency, points per game and red-zone efficiency.

— While the Jaguars have scored touchdowns on just 5-of-18 trips inside their opponents’ 20-yard line, the 49ers defense ranks 31st in that area by yielding touchdowns on 14-of-20 red-zone drives.

— Turnovers have come in bunches lately for the 49ers, and they own a plus-four differential. The Jaguars are minus-seven, largely doomed by 12 interceptions.

— After leading 24-0 through three quarters Sunday at Tennessee, Colin Kaepernick then failed to complete his final three passes, dropping his fourth-quarter passer rating this season to 54.4, or 31st in the league.

— Kaepernick ranks sixth in terms of third-down passing with a 101.7 rating. He’s completed 60 percent of third-down passes. Five of his eight touchdown throws have come on third down, as have two of five interceptions.

— The Jaguars may start Chad Henne for a fifth game in place of Blaine Gabbert, who’s been battling a bad hamstring (and ineffective play). Henne has the league’s 28th passer rating (72.9) with five interceptions and two touchdowns. Gabbert (one touchdown, seven interceptions) has appeared only three games, so his 36.0 passer rating is spared from qualifying among the league’s worst.

— The 49ers have two of the league’s top-50 receivers: No. 27 Anquan Boldin (34 catches for 495 yards and two touchdowns) and No. 50-tie Vernon Davis (24 receptions for 466 yards and six touchdowns).

— With three interceptions apiece, Eric Reid and Tramaine Brock are tied for the sixth-most in the league.

— Aldon Smith, who’s missed the past four games, still ranks 15th among the league’s sack leaders with his total of 4 ½.