ANTI-AGING BREAKTHROUGH:

Thymic Protein A

An Interview with Dr. Terry Beardsley on his new
discovery.

Dr. Terry Beurdsley is an immunologist with a Ph.D.
in Experimental Biology from Baylor College of Medicine, Texas.

He has been
the principal scientist in the Monoclonal Antibody Facility at Smith Kline
Beckman; Assistant Professor of Research at the University, of California at San Diego; Research Associate at Scripps Clinic,
La Jolla; and Assistant Research Professor at UCLA Laboratory of Nuclear
Medicine.

He has spent most of his career researching the thymus gland, and is considered
one of the experts on this subject.

He is the first person to isolate and
purify an intact thymic protein and make it available for commercial use.

TH:

Dr. Beardsley, you have recent been
awarded a U.S. patent for your important discovery of a whole thymic peptide
called Thymic Protein A, which promises to extend human life span through
its major role in strengtbening the human immune system.

A:

I would like briefly to explain the function
of the human immune system for your readers, before I discuss my discovery.

First, let me say that it is now established in medicine that a strong immune
system increases life span by protecting the body from the daily attacks
of pathogens in our environment, as well as slowing down the diseases of
aging.

Any substance which measurably strengthens immunity may well extend
life and, most importantly, quality of life.

Witness all the new research
to find agents to improve immunity in the treatment of cancer and other
degenerative diseases.
We know that the immune system is a
complex network of specialized organs,
glands and cells and it is composed of two
basic sub-systems, the Humoral and the Cell
Mediated, each with different methods of
defending the body against disease.

B-lymphocytes (B-cells) and T-lymphocytes (T-cells) are types of white blood cells utilized as soldiers
by the immune system.

B-cells are the antibody producers used in Humoral
Immunity and T-cells are the shock troops used in Cell Mediated Immunity. They
are all born in the bone marrow.

B-cells mature in the bone
marrow, hence the B for bone marrow.

T-cells are matured by
proteins from the thymus gland.

Both sides of the immune system
must function properly in order for the body to have an optimum immune response
to invading pathogens. In fact, B-cells will react quicker, proliferate and
produce an antibody response more efficiently in the presence of a T-cell
response.

So the presence and sufficient
activity of T-cells is crucial for maximum immunity in an individual.

TH:

We bear a lot ubout the importance of T-4 cells as regulators of the
immune system. Please elaborate.

A:

Of all the cells
in the immune system the T-4 helper cell is the most important
because it serves as controller of many key functions of immunity. It’s like the
“conductor who keeps
an orchestra playing in tempo and in tune.

It regulates the delicate balance
of the immune system by secreting certain lymphokines and cytokines, among them
Interleukin-2 and Interferon, which act as “messengers” to tell specific cells
to attack and destroy certain invading pathogens.

The T-4 cell is also necessary to
interact with B-cells, as it transforms them into cells which produce antibodies
to a particular antigen.

In addition, the T-4 cell calls
upon the bone marrow to manufacture more of itself and other types of T-cells
and has a role in the production of total white blood cell levels, red blood
cells and production of the important CD56 natural killer cells, which also
attack and destroy cancer cells, among others.

The key word in all this is
“regulation.”

We are beginning to understand
that the body has its own methods of keeping balance. The cause of many
degenerative illnesses is increasingly viewed as a “dysregulation” of immunity.

For example, autoimmune diseases
such as Lupus, Multiple Sclerosis or Arthritis are now understood to be caused
by too strong an immune response of certain cells, which actually attack the
body.

Cancer, Chronic Fatigue Syndrome
and AIDS are examples of illnesses which involve a weakened immunity.

In the past, medicine has tried
to either strengthen or decrease immune response by certain synthetic agents and
drugs. I do not believe in forcing an immune response.

I feel that the correct way to
deal with these illnesses is by a well-regulated immune system.

Since the T-4 cell is the key to
regulation, we need to cooperate with nature by protecting and strengthening its
activity, rather than interfering with or forcing it to behave in a certain
manner.

The widespread use of
chemotherapy and radiation in treatment of cancer are well-known as damaging to
the immune system.

In many cases, the patient who
receives these treatments damages the T-cells and thus his or her ability to
mount a sufficient immune response to the constant stream of pathogens which
enter the body every day.

Many people treated for cancer
die of opportunistic infections which would normally be easily handled by a
strong immune system. While a healthy young person aged 21 has an abundance of
well-functioning T-cells to regulate the immune system, by the age of 40 most
adults’ immunity has been significantly decreased.

Now we are learning that this is
due to a lack of properly programmed T-cells and the shrinking of the thymus
gland.

TH:

What is the role of the thymus gland
in immunity?

A:

Since T-4 cells are naive (immature) when born, they will not function
unless they are programmed by certain thymic protein.

I have been fortunate
enough to be one of the
first to discover a specific substance which
activates the T-4 cell; which I call Thymic Protein A.

I am the first scientist to
produce this protein in an intact manner in the laboratory so that it can be
administered to people to help regulate their immune systems.

The thymus is a ductless gland which lies
just beneath the breastbone. We now know
that it begins to shrink after puberty. By age
40 an average human has only a small portion of the thymus still intact
as the glandular tissue converts to connective and fatty tissue.

In the past 30 years research has shown
that newly-born (naive) T-lymphocytes
migrate from the bone marrow to the thymus where they are programmed to
distinguish
between self and non-self.

Three
main classes of cells are produced:

T-4 helper cells, which help to signal
and to turn on certain functions and stimulate production of antibodies
by the B-lymphocytes;

T-8 cytotoxic (killer)
cells, which are guided by the T-4 helper cells to attack and destroy
invading cells such as viruses and cancer cells;

and T-S suppressor cells,
which are necessary to terminate attack by the T-8 killer cells.

TH:

We have beard of using thymus extracts to treat immune deficiency. How
does Thymic Protein A compare with these extracts?

A:

For many decades physicians have treated deficiencies involving the thyroid
gland, the pancreas, and adrenal gland with physiologic replacements, with
the theory:
If a gland dries up, replace it.

Extracts of
thymus generally consist of whole thymus
gland which is ground and dried or strained
into liquid and administered in capsules or in sublingual drops.

By the
very nature of how these extracts are processed, the resultant product is
a conglomeration of thymus tissue, cell debris, fragments of thymus proteins
and thymus by-products.

These extracts are only slightly effective because
they are mere fragments. To attain full effectiveness a protein must have
a specific shape with exact transmitter and receptor sites.

It is therefore
logical that since supplying whole but biologically
inactive thymus in a processed and
fragmented form helps people with thymus
deficiencies, it would be much more effective to supply a purified single
thymus protein which is still biologically active.

The new intact thymic protein I call Thymic Protein A is the
complete 500-amino chain which fits the receptor site on the T-4 cell.

The
protein acts like specific software which turns on the computer
(in this case the T-4 cell). No other thymic extract known compares because
none of them are intact.

Due to the processing methods I explained
previously, they contain only fragments of the whole protein and do not
fit the T-4 receptor. Thats why even drugs like thymosin, a patented
thymic fraction, on which many millions of dollars have been spent in development,
has shown only a mild positive effect, and only when used together with
doses of interferon to treat hepatitis.

TH:

What benefit to Longevity does
Thymic Protein A offer?

A:

As I stated previously, the thymus has
atrophied by the age of 40 and no longer
produces sufficient proteins to program
newly-born T-cells properly.

It may well be
determined that the atrophy of the thymus
is one of natures methods of programmed
death for humans.

Longevity medicine
seeks to extend life by measuring the bodys
vital functions, to determine which organs
are performing at reduced capacity, and
attempt to restore their function by replacing
the missing natural substances such as
hormones.

Witness the use of human
growth hormone, melatonin, DHEA and
other substances.

We now have added to our arsenal one of the most important
of these natural replacements, Thymic Protein A.

A daily dose of a mere 4 micrograms of
this material can make a major difference in
longevity by strengthening the immune system through its T-cell programming
role.

The more T-cells that are
properly functioning, the more immune response
may be mounted against all infections and pathogenic agents which are constantly
entering the body.

TH:

What kinds of results have you gotten
with Thymic Protein A?

A:

The benefits to strengthening the
immune system with Thymic Protein A
include increased stamina, energy, well-being and ability to ward off infections.

Clinical research is already underway, and one pilot study recently completed
showed that a dose of 12 micrograms of Thymic Protein A daily for 60 days
produced a 50 percent or greater reduction in the level of Early Antigen
Epstein-Barr viral loads in 67 percent of individuals tested.

These results
simply confirm the positive anecdotal reports we have received from sufferers
of Chronic Fatigue Syndrome. Another study is underway on Hepatitis C.

In
the four years that Thymic Protein A has been available, anecdotal reports
have shown protection against flu, resolution of many types of infections, from
minor to major, as well as benefits in serious illnesses such as cancer.

Most significant are numerous
reports from people undergoing chemotherapy who have taken this substance and
maintained their total white blood count at acceptable levels.

It is well-known among
oncologists that chemotherapy and radiation will often induce a serious drop in
white blood count to dangerous levels which may dictate cessation of therapy.

TH:

Are any doctors using Thymic
Protein A?

A:

Yes, indeed. Dr. Julian Whitaker has
called Thymic Protein A: Likely the most
powerful natural stimulant of the immune
system ever discovered.

Many other physicians such as Drs. Robert
Atkins, Abram Ber, Jonathan Wright, Lee Cowden and Serafina Corsello, are
using it regularly in their practices and for themselves.

TH:

In what form is Thymic Protein A available?

A:

Thymic Protein A is sold as a powder
in sealed individual dose packets, administered under the tongue, where
it rapidly dissolves.

Each box contains 30 packets. The suggested use is
from l-3 packets per day.

Those who wish to improve their immune function
may use one packet daily, or every other day.

Higher doses are not harmful
and may be used with additional benefits.

Some individuals with serious
health problems may require higher doses for periods of time. Because the
product is so highly purified, no allergic reactions should occur, as is
possible with whole thymus extracts.

The product is made from cultured cells,
not from actual thymus glands. No animals must be sacrificed and there are
no considerations of the health of the donor animal, as there would be with thymic extracts from whole glands.

The potential of this new thymic protein
is just beginning to be realized.

The implications for protection against
infections and overall slowing of the aging of the immune system are only
a few of the possible benefits of this unique substance.

One day in the
near future all medicine will utilize this protein, with an array of other, natural substances to protect against the very causes of illness and aging. exciting
for both designers and users.