Use existing NeuroMatic code
to create your own Hodgkin-Huxley-like models
that run within the NeuroMatic environment.

Select a model using the Model Select drop-down menu at the top of the Model Tab.
Key parameters such as the resting membrane potential (V0), membrance capacitance (Cm),
membrane conductance amplitudes (gNa, gK, gLeak...) and reversal potentials (eNa, eK, eLeak...)
are displayed in the ListBox control and can be edited here.

Code –
view the NeuroMatic procedure code for the currently selected model
(also see Igor Menu/NeuroMatic/Procedures/Model).

This figure shows an IAF simulation (black) of a cerebellar granule cell
receiving the sum of 4 mossy-fiber synaptic inputs.
The synaptic inputs have an AMPA-receptor component (gAMPA, n=4; red)
and NMDA-receptor component (gNMDA, unblocked, n=4; green).
The conductance trains were computed via the
Pulse Tab
by clicking the Model Button
and selecting
“Granule Cell Synaptic Conductance Train with Short-Term Plasticity”.
The resulting Pulse Waves had prefix names
“gAMPA” and “gNMDA”,
which were entered as values for
the Model Tab ListBox parameters
gAMPA_WavePrefix and gNMDA_WavePrefix.
Some of the parameters for this IAF simulation
can be seen in the above screenshot of the Model Tab.

This figure shows 3 overlaid simulations of the
Hodgkin-Huxley Model
for a single compartment with -65 mV resting potential.
A 70 ms current step was injected at 10 ms,
with amplitude 50, 100 and 150 pA (red, green and blue)
via the ListBox parameters
iClampDuration, iClampOnset,
iClampAmp and iClampAmpInc.

This figure shows two overlaid simulations of a
ventral cochlear nucleus bushy cell (Type II) model
configured by selecting “Rothman_VCN”
in the top model-select drop-down menu.
A 100 ms current step was injected at 10 ms,
with amplitude -500 and 500 pA (red and blue)
via the ListBox parameters
iClampDuration, iClampOnset,
iClampAmp and iClampAmpInc.