Browse our MDM2 (MDM2) ELISA Kits

On www.antibodies-online.com are 9 Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) ELISA Kits from 5 different suppliers available. Additionally we are shipping MDM2 Antibodies (384) and MDM2 Proteins (15) and many more products for this protein. A total of 444 MDM2 products are currently listed.

The study found the frequency of Mdm2 SNP309 G/G in the Thai population to be very low, and suggests that this can explain to some extent the low incidence of severe inflammation and gastric cancer changes in the Thai population.

the MDM2 SNP309 G/G homozygous genotype might be a risk factor for gastric cancer in Thailand

The proposed non-linear feedback control and perturbations compensation method for the p53 (show TP53 ELISA Kits)-mdm2 system can result in more efficient chemotherapy schemes where the infusion of medication will be better administered.

physiological activation of the 5S RNP (show RNPC3 ELISA Kits)-Mdm2-p53 (show TP53 ELISA Kits) pathway may contribute to functional decline of the hematopoietic system in a cell-autonomous manner over time.

MDM2 maintains homeostasis and long survival in podocytes preventing apoptosis.

MDM2 Antigen Profile

Antigen Summary

This gene is a target gene of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of this gene can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein has E3 ubiquitin ligase activity, which targets tumor protein p53 for proteasomal degradation. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. More than 40 different alternatively spliced transcript variants have been isolated from both tumor and normal tissues.