Deutsche Leitlinien

ESMO Clinical Practice Guidelines by Tumour Type

According to the ESMO the ESMO Clinical Practice Guidelines (CPG) are intended to provide oncology professionals with a set of recommendations for the best standards of cancer care, based on the findings of evidence-based medicine.

Each Clinical Practice Guideline includes information on the incidence of the malignancy, diagnostic criteria, staging of disease and risk assessment, treatment plans and follow-up designed to help oncologists deliver an appropriate quality of care to their patients.

Cancer Council Australia: Wiki-based clinical practice guidelines

The Cancer Council Australia wiki platform is web-based information and education on clinical practice guidelines and that can be constantly updated.

The Wiki-based clinical practice guidelines will ultimately improve the standard and consistency of clinical practice according to the best and most recent scientific evidence available. It is a service provided by Cancer Council Australia to inform clinical practice. Unlike written guidelines wiki guidelines are constantly updated as new evidence becomes available and are linked to source abstracts and other evidence-based sites that add to the value of visiting the wiki site.

PDQ® - NCI's Comprehensive Cancer Database

PDQ Cancer Information Summaries

According to the NCI Website the PDQ (Physician Data Query) is NCI's comprehensive cancer database. It contains summaries on a wide range of cancer topics; a registry of 8,000 open and 19,000 closed cancer clinical trials from around the world; and a directory of professionals who provide genetics services. PDQ also contains the NCI Dictionary of Cancer Terms, with definitions for 6,800 cancer and medical terms, and the NCI Drug Dictionary, which has information on 2,300 agents used in the treatment of cancer or cancer-related conditions.

The PDQ cancer information summaries are peer-reviewed, evidence-based summaries on topics including adult and pediatric cancer treatment, supportive and palliative care, screening, prevention, genetics, and complementary and alternative medicine. Most of the summaries are available in two different formats:

Health Professional versions provide detailed information written in technical language and are fully referenced with links to PubMed abstracts.Patient versions are written in lay language and include links to the NCI Dictionary of Cancer Terms. Many patient summaries also include illustrations.Both versions of the summaries are available to health professionals, patients, and the general public as a service of the NCI. Some of the summaries are also available in Spanish.

According to the NCI Website the adult treatment summaries provide prognostic and treatment information on the major types of cancer in adults. Summaries are available for over 70 types of cancer, including a number of brief summaries on less common cancers. Health professional versions of the summaries provide detailed information on prognosis, staging, and treatment for each disease; refer to key citations in the literature; and link to abstracts for the citations. All of the PDQ adult treatment summaries are available in patient versions and in Spanish.

According to the NCI Website the pediatric treatment summaries contain prognostic and treatment information on the major types of cancer in children, as well as information on unusual childhood cancers. Health professional versions of the summaries provide detailed information on prognosis, staging, and treatment for each disease; refer to key citations in the literature; and link to abstracts for the citations. All of the PDQ pediatric treatment summaries are available in patient versions and in Spanish.

According to the NCI Website the PDQ's supportive and palliative care summaries provide descriptions of the pathophysiology and treatment of common physical and psychosocial complications of cancer and its treatment, such as pain, hypercalcemia, and nausea/vomiting. Each health professional version generally contains an overview, information on etiology, assessment and management, and references to the current literature. All of the PDQ supportive and palliative care summaries are available in patient versions and in Spanish.

According to the NCI Website summaries on screening/detection for many of the common cancers such as lung, colorectal, breast, and prostate, as well as other cancers, are available. The health professional-oriented summaries contain current data concerning screening/detection for particular disease sites, the levels of evidence for those statements, and the significance and evidence of benefit for the statements, which include supporting references to current literature. All of the PDQ screening/detection summaries are available in patient versions.

According to the NCI Website summaries on prevention for many of the common cancers such as lung, colorectal, breast, and prostate, as well as other cancers, are available. Health professional versions of the summaries contain current data concerning prevention for particular disease sites, the levels of evidence for those statements, and the significance and evidence of benefit for the statements. Supporting references to current literature are included. All of the PDQ prevention summaries are available in patient versions.

According to the NCI Website the PDQ genetics summaries provide evidence-based information about the genetic basis of certain cancers. Information is given about risk factors related to family history, major genes and syndromes associated with the disease, interventions specific to individuals at high risk, and the ethical, legal, and social issues related to cancer risk counseling and gene testing. An overview of cancer genetics and summaries on the genetics of breast and ovarian cancer, colorectal cancer, medullary thyroid cancer, prostate cancer, and skin cancer are currently available. A summary covering the elements of cancer risk assessment and counseling is also available.

According to the NCI Website the health professional versions of the summaries contain background information about the treatments; a brief history of their development; information about their proposed mechanism(s) of action; and information about relevant laboratory, animal, and clinical studies. Most of the summaries also are available in a patient version that is written in a question-and-answer format. All complementary and alternative medicine summaries include glossary links to definitions of scientific terms.

ASCO Behandlungsguidelines

According to ASCO the guidelines can address specific clinical situations (disease-oriented) or use of approved medical products, procedures, or tests (modality-oriented). Using the best available evidence, ASCO expert panels identify and develop practice recommendations for specific areas of cancer care that would benefit from using practice guidelines. Learn more about ASCO's Guideline Development Process.

British Columbia Cancer Agency Guidelines

Cancer Management Guidelines

As part of its responsibility to establish a coordinated, province-wide program of cancer control for residents of British Columbia, the BC Cancer Agency has prepared these cancer management guidelines, based on the accumulated experiences of this Agency together with "best" practice evidence derived from major cancer centres throughout the world.

The recommendations have been developed by provincial tumour groups comprised of oncologists, radiologists, pathologists, oncology nurses, pharmacists and practitioners from health disciplines contributing to specialized oncology care at the BC Cancer Agency and University of British Columbia.

News

In the largest study so far undertaken, US researchers have shown that testosterone replacement slows the recurrence of prostate cancer in low-risk patients. This may call into question the general applicability of Nobel-Prize winning hormonal prostate treatment. The work is presented at the European Association of Urology congress in Barcelona.