Lyndra said today that it won a 5-year grant from the National Institute of Allergy and Infectious Diseases, a branch of the National Institutes of Health. The grant is slated to support the formulation and preclinical development of a once-weekly oral HIV treatment. The Watertown, Mass.-based company makes use of a sustained-release technology developed by Robert […]

Researchers from the Massachusetts Institute of Technology, Brigham and Women’s Hospital and the Charles Stark Draper Laboratory have developed the means to wirelessly power electronic devices that stay in the digestive tract indefinitely. The team suggests that these devices could be used as sensors in the GI tract or carry drugs to be delivered over […]

Lyndra, Inc. said today that it closed a $23m Series A round, led by Polaris Partners, to fund the development of its long-acting therapeutic oral delivery platform. Quark Venture, GF Securities, Yonghua Capital, Healthlink Capital, Partners Healthcare, Suffolk Equity and others invested in the round. The Watertown, Mass.-based company touts its tech as the 1st […]

Massachusetts Institute of Technology (MIT) and Boston Children’s Hospital researchers have discovered a way to prevent fibrosis from forming around medical device implants by blocking certain cells. The body’s immune system usually attacks implanted medical devices that are used for drug delivery, sensing or tissue regeneration. Defense cells in the body try to isolate the […]

Researchers from the Massachusetts Institute of Technology have developed a way to amplify certain types of cancer treatment by tethering nanoparticles to cancerous tumor cells. The team’s work was published in Nature Communications. The researchers found that tethered nanoparticles increase the forces exerted on the cells by phenomena such as blood flow, therefore making the cells […]

MIT engineers and biologists teamed up and designed a living-cell-injected hydrogel that can illuminate when exposed to certain chemicals. The MIT team made wearable sensors using the hydrogel with living cells that lit up after touching a surface with certain chemicals. The new material has the potential to detect chemicals in the environment and the […]

MIT and Brigham and Women’s Hospital researchers have announced an ingestible device innovation: a small voltaic cell that can withstand the acidity of fluids in the stomach and still transmit information to a base station. The small device can stay in the gastrointestinal tract for long periods of time and can produce enough power to […]

The ongoing opioid crisis in the U.S. is harrowing – 91 Americans die every day from an opioid overdose, according to the Centers for Disease Control & Prevention. Companies are searching for innovative ways to deliver opioid maintenance treatment to patients that are hoping to get clean. Buprenorphine is a compound used for medication-assisted treatment, traditionally administered […]

Robert Langer, a pioneer in drug delivery and the most cited engineer in history, has co-founded 30 companies and treated more than 20 million patients as a result of his innovations. In a conversation with Wired, he spoke about his career, which has spanned for 4 decades and began with his 1976 discovery of a method to delay […]

Researchers from the Massachusetts Institute of Technology and Brigham & Women’s Hospital have developed a technique to deliver strands of RNA to colon cells using bursts of ultrasound waves. The team’s technique turned down the production of a protein involved in inflammatory bowel disease in mice. The paper, which was published in Gastroenterology, described a simple […]