This is the second patent issued to the Company covering dicationic compounds for the treatment of fungal infection; the patent covers dications for the treatments of Candida albican, Cryptococcus neoformans, Aspergillos fumigatus and Fusarium Solani, and also covers compounds that incorporate bis-benzimidazoles and furan chemical structures.

The analytic serotype sensitivities for the LFA, two currently available LAs, and an ELISA were compared using purified glucuronoxylomannan from multiple strains of four serotypes of Cryptococcus neoformans and C.

Mitigating against the need for optimal detection of all fungal pathogens by blood culture, alternative and more sensitive methods exist for detection of Cryptococcus neoformans, Aspergillus fumigatus, and other filamentous fungi; specifically, the cryptococcal antigen test, the Platelia galactomannan assay (Bio-Rad, Hercules, Calif) for invasive aspergillus, and the Histoplasma urinary antigen test.

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