I would like to statically link my app to ProfUIS --trying to build the static version of the ProfUISDLL - I have read the FAQ and it seems to imply that this configuration exists in the project...but when I open the ProfUISDLL project there is no ’Static ...’ configuration. When I build my project with the Use of MFC : Use MFC in a Static Library I get a linker error: cannot open file ’ProfUIS254sm.lib’

The problem is that you are opening the wrong project. ProfUISDLL project contains all the build configuration for dynamically linked library(thus the DLL in name). All statically linked libraries can be built in the ProfUISLIB project. A quote from the Prof-UIS Build Configurations feature article:

"Supported Project ConfigurationsThe following table lists the supported project configurations and corresponding library files. You can find configurations 1-12 in the ProfUISDLL project. After compiling the library using any of these configurations, you will get two files with .lib and .dll extensions, which you can further use in your project. All the static configurations 13-36 are defined in the ProfUISLIB project."