Written by Keith Giffen, penciled by Scott Kolins and Ariel Olivetti, cover by Gabriele Dell'Otto.

This is it! 48 pages of cosmic guts and glory! If you want to see your favorite cosmic level heroes and villains, you dare not miss Annihilation: Prologue! This is the book to read for the NEXT YEAR'S worth of cosmic stories! Get in on the ground floor as Marvel raises these great characters from the ashes!Heroes will die. Villains and heroes will form allegiances. Empires will fall. Featuring: Nova, Silver Surfer, Thanos, Drax the Destroyer, Ronan the Accuser and the Super-Skrull.