A lonely, aging movie star named Bob Harris (BILL MURRAY) and a conflicted newlywed, Charlotte (SCARLETT JOHANNSON), meet in Tokyo. Bob is there to film a Japanese whiskey commercial; Charlotte is accompanying her celebrity-photographer husband. Strangers in a foreign land, the two find escape, distraction and understanding amidst the bright Tokyo lights after a chance meeting in the quiet lull of the hotel bar. They form a bond that is as unlikely as it is heartfelt and meaningful.