The formulation of LowCross-Buffer helps to reduce immunoassay interference and can therefore significantly improve the quality of detection. Nonspecific binding of the antibodies, negative effects of interfering substances and low or medium affinity cross reactivities of the antibodies can be significantly reduced. In addition matrix effects, coming for example from blood sera or plasma specimens are minimized. Reduction of all these negative effects improves the quality of the assay and the reliability of your immunoassay results.

LowCross-Buffer is used to replace your standard sample or antibody dilution buffer.

Reduce immunoassay interference caused by:

cross reactivity

non-specific binding

matrix effects

HAMAs (Human Anti-Mouse Antibodies)

rheumatoid factor

LowCross-Buffer® is a ready-to-use sample and antibody dilution buffer that can be substituted for your standard assay buffers to improve the quality of immunoassays, including

ELISA

EIA

WB

IHC

RIA

Protein Arrays

Immuno-PCR

LowCross-Buffer® acts like an "affinity gatekeeper", shielding the specific signal from low affinity cross-reactivities and interferences.

Examples:

ELISA

Click here to see paragraph 2.7 where LowCross Buffer was stated to have helped to avoid cross reactivities