Patients complete a detailed epidemiological questionnaire, including information on education, occupation, smoking habits, alcohol consumption, height, weight, family history of cancer, and past medical history.

Blood samples are collected from patients. DNA is extracted from these blood samples and from samples collected from cancer-free control participants in MREC-SEARCH-CONTROL as well as from additional controls through the European Prospective Investigation of Cancer (EPIC) study (a population based study of diet and health based in Norfolk, East Anglia). DNA samples are analyzed for polymorphisms of low penetrance cancer susceptibility genes.

In addition to the prostate cancer patients recruited for this study, patients with breast, ovarian, endometrial, colorectal, bladder, kidney, pancreatic, brain and esophageal cancer, malignant melanoma, and lymphoma cancer are recruited in the following related clinical trials: MREC-SEARCH-BREAST, MREC-SEARCH-OVARIAN, MREC-SEARCH-ENDOMETRIAL, MREC-SEARCH-COLORECTAL, and MREC-SEARCH-CANCER.

Inclusion Criteria

DISEASE CHARACTERISTICS:

- Diagnosis of prostate cancer within the past 5 years

- Identified through the cancer registry serving any of the following geographic regions of the United Kingdom:

- East Anglia

- Trent

- West Midlands

PATIENT CHARACTERISTICS:

- Identified by the patient's general practitioner as fit to contact for this study

- No serious mental illness or retardation

PRIOR CONCURRENT THERAPY:

- Not specified

Type of Study:

Observational

Study Design:

N/A

Outcome Measure:

Acquisition of epidemiological information and biological material

Safety Issue:

No

Principal Investigator

Paul Pharoah, MD

Investigator Role:

Study Chair

Investigator Affiliation:

Cancer Research UK

Authority:

Unspecified

Study ID:

CDR0000589199

NCT ID:

NCT00758173

Start Date:

February 2008

Completion Date:

Related Keywords:

Prostate Cancer

prostate cancer

Prostatic Neoplasms

Name

Location

We are a Cancer Social Network, Resource Directory & Education Hub supporting all those affected by cancer. knowcancer.com is intended to be solely for informational purposes and should not be a substitute for professional medical advice, diagnosis or treatment.