Antibodies with simultaneous subsite specificities to protein and lipid epitopes

US Patent No. 9119828

Issued: September 01, 2015

Status: Active

Antibodies and method of making antibodies, either monoclonal or polyclonal wherein said antibodies have dual or multi-specific binding capacity to more than one type of antigenic epitope. The antibodies have simultaneous or independent recognition subsites to each of the epitopes. Antigenic epitopes include lipids, peptides, proteins, amino acid sequences, sugars and carbohydrates. Monoclonal antibodies and a method of making monoclonal antibodies of the invention include monoclonal antibodies that are broadly neutralizing to HIV-1 or other envelop viruses wherein the monoclonal antibody has subsites that simultaneously recognize protein and lipid epitopes from the virus.

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Austin Leach, PhD, CLP

Austin Leach, PhD, CLP

Austin joined TechLink in 2014 and specializes in advanced materials and nanotechnology licensing. He is also leading technology marketing initiatives for TechLink. Prior to joining TechLink, he honed his technical skills in medical device R&D at Abbott Laboratories, working on cardiovascular implants and next-generation continuous glucose monitoring systems for diabetes management. Austin has a doctorate in materials science and engineering. In addition to traveling to exotic destinations with his wife, Austin enjoys playing guitar, raising dogs and organic produce, and exploring galaxies far, far away.