Abstract: Lack of stringent measures in safety and construction laws has been attributed to poor performance in Health and Safety (H&S} in the construction industry. The purpose of the paper is to present how the conceptualized integrated H&S compliance model for contractors in Ghana will be developed. The conceptualized model theory forms the bases of the discussion in this paper. A total number of fifteen studies relevant to accident causation theories were selected out of the total number of thirty studies reviewed, through a rigorous process. The assessment of H&S compliance model for the study was carried out through the combination of objective and subjective attributes. The Domino Theory forms the basis for theoretical and conceptual framework of this paper. The study adopted various constructs from Accident Root Causes Tracing Model (ARCTM) and Domino theory. The hypothesized integrated holistic H&S compliance model is presented in this paper based on an in-depth review of the previous models. Government support and contractor's organizational culture serve as variable constructs identified as gaps in H&S compliance research. Discussions also included the integrated holistic model and the variables of the model, identification of the model and justification for the selected variables. The paper presented the conceptualized H&S compliance model. The gaps identified in H&S compliance research served as the variable constructs. They are government support and contractor's organizational culture.