The Distillation

The researchers said MDMA appears to enhance the extinction of the conditioned fear by altering neuronal activity in the amygdala, a brain structure associated with memory and emotions.

Researchers have discovered that MDMA — commonly known as ecstasy or molly — speeds up the extinction of the conditioned fear response in mice. The findings help explain why the psychedelic drug is of benefit to people suffering from post-traumatic stress disorder. Clinical studies have found that using MDMA as an aid during psychotherapy resulted in long-lasting improvements in PTSD symptoms. But Matthew Young of Emory University and his colleagues wanted to understand the psychological mechanism behind these results. The researchers said MDMA appears to enhance the extinction of the conditioned fear by altering neuronal activity in the amygdala, a brain structure associated with memory and emotions.

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