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NFL Picks

Week 10 NFL Picks: Game-by-Game Against the Spread Odds & Predictions

Here's an NFL Week 10 betting cheat sheet. Each week of the season, you will find the entire slate with picks ATS and each capper's quick-hitting reasoning. SBR also will have full previews of each week's prime-time and marquee games.

PANTHERS

STEELERS

Matthew Jordan: Pittsburgh has covered six all-time meetings in series. Carolina not great in road losses in Atlanta and Washington and is 2-5 ATS in past seven after a win. Wish this was at -2.5.

Rainman: Panthers finally have to hit the road, where they don’t play as well. Steelers have found their groove with Conner at running back. Their defense has also strongly improved. They’re 4-0 L4 ATS.

Swinging Johnson: Pittsburgh just beat one of the best defenses on the road while Panthers defeated the worst defense at home. Steelers D has not allowed >21 pts since Week 5 and offense is clickin’.

Doug Upstone: Have to admit to giving strong consideration to backing Carolina at Pittsburgh, before finding the Panthers are 2-10 ATS on the road after scoring 30 points or more in two straight games.

Kevin Stott: good matchup from The Mustard Palace where the series (PIT 6-0 ATS L6, 3-0 ATS L3 Home) and Thursday Night (CAR 1-7 ATS) Trends both point to backing Big Ben and the Black and Yellow (W4).

LIONS

Doug Upstone:Chicago seems like an obvious chose over Detroit off two wins and a pair of Lions setbacks. But Detroit is 7-0 ATS in road games after trailing their last two games by 10+ points at the half.

BEARS

Matthew Jordan: The Bears are expecting Khalil Mack back, and that spells trouble for Matthew Stafford as he was just sacked 10 times by Vikings. Chicago’s 10-game in-division losing streak ends.

Rainman: Detroit will have that much more trouble scoring against Chicago’s elite D after trading Tate. Also, Golladay has fallen out of favor with Stafford. Chicago will gash Detroit’s bottom-ranked run D.

Swinging Johnson: I’m not sure what kind of a number the oddsmakers would be able to deal that would hook me into backing the Lions on the road. Bears superior in every facet as Patricia comes unraveled.

Kevin Stott: Chicago leads NFC North, but only team not to have won game in it. Bears 3-15 SU L18 before Vikes, 10-16-1 ATS L27 Home Faves but didn’t have QB like Trubisky, a shot at division most of those years.

BENGALS

Matthew Jordan: Cincinnati isn’t as good as New Orleans, and Bengals will be without A.J. Green. But Cincy is off its bye week, and this just feels like a letdown game for Saints off huge Rams win.

Rainman: This is a tough spot for the road faves. After upsetting the undefeated Rams, the Saints will have to travel and try to avoid a let-down. Dalton and his weapons can exploit NO’s bottom-ranked pass D.

Swinging Johnson: If this doesn’t scream trap then you haven’t been around long enough. NO off huge win over LA and looking ahead to game with defending SB champs after this. Cats are a live home pup.

Doug Upstone:Atlanta has won three in a row and Matt Ryan is hot. It is hard to imagine Cleveland's leaky defense is going to find a way to slow the Dirty Birds down. The Browns are 2-9 ATS off a home game.

Kevin Stott: Last back-to-back Browns (3-0 ATS L3 series) wins were in 2014 when Baker Mayfield was a soph at Oklahoma and got 0 snaps with Trevor Knight the Sooners starter and Cody Thomas the backup.

BROWNS

Rainman: I love the new O-coordinator. He knows how to utilize Duke Johnson, who will again be a weapon against Atlanta’s awful linebackers. Atlanta shouldn’t be favored away with its decimated defense.

PATRIOTS

Matthew Jordan: Trap game potential for some teams, but Patriots don’t seem to have those. Plus, they should get Gronk back and are 5-0 ATS in past five meetings. Titans on a short week too.

Rainman: It’s too risky to bet against the Patriots with a spread of a touchdown or lower. Tennessee’s secondary has been helpless against top quarterbacks like Wentz and Rivers. Brady will find a way.

Swinging Johnson: Titans got a nice win over Dallas but working on a short week and that’s a recipe for disaster when facing TB12 and The Evil Genius. Patriots are 8-2 SU and 7-3 ATS vs. Tennessee.

Doug Upstone: Off a nice road underdog win at Dallas, Tennessee would seem like a nice potential home dog. Then you realize New England is 17-5 ATS after three or more wins the last three seasons.

Kevin Stott: With Gronk iffy and Rookie Michel out, Brady’s weapons for NE are down but Edelman has been his usual sparkplug self and the Titans O’s fade-worthy (106 points). Tennessee has L3 straight.

TITANS

JAGUARS

Matthew Jordan: Both teams off their bye and heading in opposite directions. The Jaguars just can’t be this bad and their defense is still much better than Indy’s. Jags have covered 6 straight in series.

Rainman: It would have been unheard of a few weeks ago to get the Jags as dogs in Indy. Rested after a bye week, this defense is still elite. The soul of Jax’s offense Fournette is expected to return.

Doug Upstone: When the season started there was not a chance in hell Indianapolis would be favored against Jacksonville in Week 10. The Jaguars end a four-game losing streak and win outright in Indy.

COLTS

Swinging Johnson: How the mighty have fallen but fallen they have, as Jax is a shadow of the team they were in 2017. Colts & Luck rolling against a suddenly vulnerable Jags’ D and a woeful offense.

CARDINALS

Matthew Jordan: I’m just always going to take this big a number in an NFL game. Cards off bye week with nada to lose, and Kansas City might be looking ahead to mega-showdown next Monday vs. Rams.

Swinging Johnson: NFL spreads are resembling college numbers but the NFL is about parity and this inflated line is there to ward off an influx of square money on the Chiefs. Stay sharp – grab the points.

Kevin Stott: Line here may be historically high (NFL Faves of 17+ 6-4-1 ATS L11) and with nothing to lose, Arizona should score at least 17 points of their own vs. the porous Chiefs D (432.4 ypg allowed, #31).

CHIEFS

Rainman: This is a huge mismatch. The Chiefs will score at will thanks to Mahomes, Hill, Hunt, and Kelce. Falling behind will expose Rosen to KC’s strong pass rush, who will make any rhythm impossible.

Doug Upstone: Oddsmakers go on the offensive this week tired of losing with Kansas City. The Chiefs offense is too strong and Arizona will commit at least two turnovers that K.C. turn into points to cover.

BILLS

Matthew Jordan: I won’t be betting on this horrific offensive matchup personally, but the Jets shouldn’t be more than a TD favorite against anyone. The Bills can keep it close with their defense.

Doug Upstone: The Jets have scored 33 points in their past three games, yet, they are about a 7-point fave. But with Buffalo averaging 7.6 PPG in their last six games, ouch. I'll grab the points and use rosary.

JETS

Rainman: Sticking to my rule to never bet on Buffalo -- even if it’s the Jets. Darnold will be more careful after throwing four picks. He’s bad, but better than that. Bills have scored 20 points in their L3.

Swinging Johnson: Darnold coming off worst performance as a pro and will be salivating at the prospect of Buffalo meat. Bills should be named Possums, both play dead at home and get killed on the road.

Kevin Stott: Airplanes 3-1 ATS L4 meetings and Bills haven’t scored a TD in 4 of their 7 Losses and have a green Roster comprised of 40% 1st-2nd year guys including Rookie QB Allen (Elbow) who has been hurt.

REDSKINS

Doug Upstone: What's the lesser of two evils, Washington offense or Tampa Bay turning the ball over? Situation favors Redskins with Buccaneers 0-7 ATS after a 2-game road trip. No Fitz-Magic in this spot.

BUCS

Matthew Jordan: The Redskins are easily the worst first-place team in the NFL and were exposed Sunday by the Falcons. The Bucs suck defensively but at least will score some behind Ryan FitzMagic.

Rainman: Difference in offensive firepower is huge, especially with the injuries to Washington’s offense. Skins rank 22nd in opposing passer rating, so expect more Fitzmagic, who will remain TB’s starter.

Swinging Johnson: One thing the Bucs can do is score but their defense is so bad it’s offensive. Yet, the Skins are in a funk and a track meet right now is not one for which they’re prepared to win.

Kevin Stott: Tough handicap at The Big Sombrero w/Skins 1-4-1 ATS L6 vs. Bucs who will be at Home and have gunslinger Fitzpatrick (#1 Passer Rating) and prolific Evans constant threats. Should be high-scoring.

CHARGERS

Swinging Johnson: Chucky’s world is crumbling anddespite the fact that laying double-digits on the road in NFL is tantamount to disaster, the Raiders are uniquely capable of making this a sound strategy.

Doug Upstone: The Chargers 19-5 ATS at Oakland and accomplished that with far lesser teams than this one and against much better clubs than the Raiders are fielding under Jon Gruden. No more Pride & Poise.

Kevin Stott: Bolts all the way w/Rivers 16-8 SU lifetime vs. the unpolished Silver and Black with 41 TDs and 18 Picks. KC’s start and Record are shadowy motivating factors for San Diego (9-18 SU L27 Road).

RAIDERS

Matthew Jordan: Raiders on extra rest and can only play better than they did at the 49ers in Week 9. Oakland lost 26-10 at Chargers in Week 5, but Bolts are 1-10 in past 10 AFC West road games.

Rainman: I know that I wrote about Oakland throwing in its towel on the season. But they have a rivalry with the Chargers, so I think they get up for this one. Double digits is too many points here.

DOLPHINS

Rainman: Green Bay has only beaten one team by more than a field goal (Buffalo) and now being asked to lay nearly double digits. I don’t trust their inconsistent defense and Rodgers can’t do it all.

PACKERS

Matthew Jordan: Desperation time for Pack, but at least not playing another powerhouse. Fins will announce whether Osweiler or Tannehill at QB by Wednesday. Like choosing between fat girls for prom.

Swinging Johnson: Scheduling gods were not happy with the Packers giving them Rams and Pats back-to-back. But GB has done its penance and is rewarded with the equivalent of shooting fish in a barrel.

Doug Upstone: Green Bay is a rather ordinary team in 2018. But a quarterback matchup of Aaron Rodgers vs. Brock Osweiler at Lambeau Field just screams of a Packers win and spread cover this week.

Kevin Stott: No more Ha Ha or Montgomery for GB (3-1 ATS L4 vs MIA, 1-3 ATS L4 at GB), but we aren’t sure that Fish swim well on ice and Mr. Rodgers is 8-0-1 L9 Home with 22 TDs, just 3 Picks, Cheddar breath.

SEAHAWKS

Matthew Jordan: Silly to bet this at 10 as it probably finishes right on that number. Seattle is good enough to hang around and nearly beat the Rams earlier this year. L.A. flat off epic Saints loss?

Swinging Johnson: In a week where spreads of 10+ are common, we believe this hound is one worthy of feeding. The Seahawks have covered 4 of last 6 and should have enough in the tank to keep this close.

Rainman: Rams’ defense has serious problems. Particularly the linebackers are mostly poor and the secondary is overrated. Both teams excel at controlling possession, so double digits is too much.

RAMS

Doug Upstone: L.A. defense is a problem. Yet after watching Seattle scuffle at home vs. the Chargers, are the Seahawks going to slow the Rams offense? The answer is a resounding NO! Angry Rams by 17.

Kevin Stott: Nice NFC West tussle from LA Memorial Coliseum with more meaning to visiting Seattle (1-5 ATS L6 at Rams). LA has the D (22.2 ppg), healthy Receivers and will be in a foul mood after that first Loss.

COWBOYS

EAGLES

Matthew Jordan: Double-whammy against Dallas as it’s on a short week and Eagles off bye – and now have Golden Tate. Have you seen the Cowboys on road this year? They 1-4 ATS in past 5 as road dog.

Rainman: Philly is built to exploit Dallas’ pass D. I love Wentz to have another big game with a 100+ passer rating. The Eagles’ second-best run D will limit Zeke, forcing Dak to throw, who won’t keep up.

Swinging Johnson: Philly has had 2 weeks to prepare while the Boyz are working on a short week. Dallas is 0-4 ATS in last 4 when playing on a Sunday following a Monday night game and looked lousy on MNF.

Doug Upstone: This would appear to be a convenient situation for Philadelphia off a bye and Dallas off a short week. The Eagles are 9-1 ATS at home after one or more wins against the spread since 2016.

Kevin Stott: Philly needs Wins, Confidence and Momentum and Wentz will look to incorporate new WR Golden Tate (Lions) into the O vs. the Cowpoke (3-1 ATS L4 at Philly) who have own new toy WR (Cooper).

GIANTS

Swinging Johnson: First there was Sweet Jimmy G and now it’s Nicky the Kid, launching for the Niners. Big Blue is coming off a bye but the sensational debut by undrafted Mullens has influenced this line.

49ERS

Rainman: SF is a lot better than its record indicates. They’ve lost three games by 3 points or less, so not much separates them from a winning record. Their better-ranked run D gives them edge here.

Doug Upstone: Garbage game in Santa Clara. Because neither defense really generates turnovers, the sloppy offense will lose and not cover. The Giants are 1-9 ATS when the line is +3 to -3 since last year.

Kevin Stott: Jints (18.8 ppg) will travel 2,896.3 miles to try to beat a team -- SF (3-0 ATS L3 series) -- without its starting QB playing in a stadium named after denim-made trousers. Edge pantalones?