..Knowledge of the responses of the brain and its vasculature to ischemia and oligemia is growing more important with the increasing availability of CT and MR perfusion techniques...

Carotid stenting for asymptomatic carotid stenosis: trial it

Colin P DerdeynMallinckrodt Institute of Radiology and the Departments of Neurology and Neurological Surgery, Washington University School of Medicine, St Louis, MO, USAStroke 38:715-20. 2007

..Randomized trials in this high surgical risk patient population must include a medical treatment arm. In this article, we will review the existing data for CAS in patients with asymptomatic atherosclerotic carotid artery stenosis...

No effect of low-dose statins treatment on cerebral blood flow in humans with atherosclerotic cerebrovascular disease

..9+/-13.5 and 44.2+/-13.3 mL/100 g min for the statin and nonstatin groups, respectively. We conclude that the stroke risk reduction observed with statin therapy in humans likely involves mechanisms other than an increased basal CBF...

..In addition, the biologic imaging of atherosclerotic plaques and hemodynamic assessment eventually will play an important role in stratifying patient risk and guiding physiologically based patient selection for intervention...

Angioplasty and stenting for atherosclerotic intracranial stenosis: rationale for a randomized clinical trial

..This article reviews these data and discusses the rationale for a randomized trial of angioplasty and stenting versus best medical management for patients who have symptomatic intracranial stenosis...

Effect of intraarterial papaverine and/or angioplasty on the cerebral veins in patients with vasospasm after subarachnoid hemorrhage due to ruptured intracranial aneurysms

..This case report is only the second to provide compelling evidence that hypertension can lead to direct dilation of vasospastic arteries, thereby providing valuable insight into its potential mechanism...

..The prudent practitioner will carefully select the patients for CAS with EPD and CEA, so that patients will have the safest opportunity to avoid the devastating effects of cerebrovascular accidents...

Traumatic enucleation with avulsion of the ophthalmic artery resulting in aneurysm-like subarachnoid hemorrhage

..The addition of asymptomatic CVD or symptomatic CVD as modifiers to the Borden-Shucart and Cognard systems improves their accuracy for risk stratification of patients with high-grade dural arteriovenous fistulas...

Transfer of a self-expanding stent to a braided microcatheter with the aid of transcatheter illumination: technical report and illustrative case

..Many different approaches to the management of this complication have been proposed. In this report, we present our experience with conservative management in two cases in which vessel rupture occurred and review the relevant literature...

..Recognition of this route of access, if present, may facilitate endovascular treatment of these lesions. Access to the transverse sinus via this approach can be straightforward and may be underused...

Clinical features and outcome in North American adults with moyamoya phenomenon

..0001). These methods may be useful for categorizing the hemodynamic status of patients with bilateral cerebral occlusive diseases, including atherosclerosis and moyamoya, to determine the association with the risk of subsequent stroke...

..The goal of this study was to determine the procedural feasibility and safety as well as long-term complication rates of carotid angioplasty and stent placement in a consecutive cohort of relatively young, high-surgical-risk patients...

Absent relationship between the coil-embolization ratio in small aneurysms treated with a single detachable coil and outcomes

..Regression analysis for localized arterial input function gave estimates of a scaling factor for quantitation that described perfusion accurately in patients with substantial variability in hemodynamic impairment...

Endovascular treatment of the vertebral artery origin in patients with symptoms of vertebrobasilar ischemia

..We report our experience with the endovascular treatment of the vertebral artery origin in patients presenting with symptomatic vertebrobasilar ischemia and compare our results with those reported in the literature...

Conventional angiography remains an important tool for measurement of carotid arterial stenosis

Colin P DerdeynRadiology 235:711-2; author reply 712-3. 2005

Training, competency, and credentialing standards for diagnostic cervicocerebral angiography, carotid stenting, and cerebrovascular intervention: a joint statement from the American Academy of Neurology, the American Association of Neurological Surgeons,

The International Subarachnoid Aneurysm Trial (ISAT): a position statement from the Executive Committee of the American Society of Interventional and Therapeutic Neuroradiology and the American Society of Neuroradiology

..Positive results from these experiments would support further investigation of a potentially important mechanism of stroke protection applicable to all patients with atherosclerotic coronary and cerebrovascular disease. ..