IndicationCINRYZE® (C1 esterase inhibitor [human]) is an injectable prescription medicine that is used to help prevent swelling and/or painful attacks in teenagers and adults with Hereditary Angioedema (HAE).

Important Safety InformationYou should not use CINRYZE if you have had life-threatening immediate hypersensitivity reactions, including anaphylaxis to the product.

Tell your healthcare provider about all of your medical conditions, including if you:

have an indwelling catheter/access device in one of your veins.

have a history of blood clots, heart disease, or stroke.

are taking birth control pills or androgens.

are pregnant or planning to become pregnant. It is not known if CINRYZE can
harm your unborn baby.

are breastfeeding or plan to breastfeed. It is not known if CINRYZE passes into
your milk and if it can harm your baby.

Allergic reactions may occur with CINRYZE. Call your healthcare provider or get emergency support services right away if you have any of the following symptoms:

wheezing

difficulty breathing

chest tightness

turning blue (look at lips and gums)

fast heartbeat

swelling of the face

faintness

rash

hives

Serious blood clots may occur with CINRYZE. Call your healthcare provider or get emergency support services right away if you have any of the following symptoms:

pain and/or swelling of an arm or leg with warmth over the affected area

discoloration of an arm or leg

unexplained shortness of breath

chest pain or discomfort that worsens on deep breathing

unexplained rapid heart rate

numbness or weakness on one side of the body

Because CINRYZE is made from human blood, it may carry a risk of transmitting infectious agents, e.g., viruses and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent.

The most common side effects seen with CINRYZE were headache, nausea, rash, and vomiting. These are not all the possible side effects of CINRYZE. Tell your healthcare provider about any side effect that bothers you or that does not go away. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. You can also report side effects to Shire Medical Information at 1-866-888-0660.

The CINRYZEConnect™ Program Participation Agreement

Participation in the CINRYZEConnect Program is completely voluntary, such that no compensation, reimbursement, or other consideration is provided by ViroPharma for participation.

ViroPharma has created the CINRYZEConnect Program for people living with hereditary angioedema (HAE), enabling them to communicate with one another and share their experiences. ViroPharma makes the initial contact possible, but after the introduction ViroPharma has no involvement with conversations between mentors and mentees.

Mentors in this program are not trained by ViroPharma. All participants acknowledge that mentors are not representatives of ViroPharma, nor do they speak on behalf of ViroPharma.

Mentors are not physicians or medical experts. Mentors are people who have been prescribed CINRYZE® (C1 esterase inhibitor [human]). CINRYZE is an injectable prescription medicine that is used to help prevent swelling and/or painful attacks in teenagers and adults with HAE. Though mentors may answer questions about living with HAE, they are not qualified to give medical advice.

All conversations are between mentors and mentees. ViroPharma would hope these conversations remain confidential. However, due to ViroPharma’s limited involvement of only making initial contact possible, ViroPharma does not and cannot guarantee such confidentiality. Conversations will not be tracked or recorded by ViroPharma. Conversation topics are decided by the mentor and mentee.

By selecting "Agree" to this Participation Agreement and then electronically signing and submitting the Authorization Form, I elect to participate in the CINRYZEConnect Program. I acknowledge that my participation in this program is completely voluntary. In addition, I acknowledge that, as a participant in the program, I am providing ViroPharma Incorporated ("ViroPharma") with certain personal medical information, which includes among other things (i) my name, (ii) my mailing and email address, (iii) my date of birth, (iv) whether I have been diagnosed with hereditary angioedema ("HAE"), and (v) which (if any) medications I am taking to treat HAE (optional).

ViroPharma is committed to maintaining the privacy and security of personal information and will protect the information that you provide pursuant to this authorization in accordance with its policies and procedures.

Indication
CINRYZE® (C1 esterase inhibitor [human]) is an injectable medicine that is used to help prevent swelling and/or painful attacks in teenagers and adults with Hereditary Angioedema (HAE).

Important Risk Information
You should not use CINRYZE if you have had life-threatening immediate hypersensitivity reactions, including anaphylaxis to the product.

I authorize ViroPharma and its partners to contact me, assign a mentor for me, and provide me with the mentor’s contact information. I authorize ViroPharma to use my medical information to send me promotional materials related to CINRYZE® (C1 esterase inhibitor [human]) and the CINRYZESolutions® and Ryze Above® Programs.

I understand that I may cancel this authorization at any time by mailing a letter requesting such cancellation to ViroPharma Incorporated, 730 Stockton Drive, Exton, PA 19341, but that this cancellation will not apply to any information already used or disclosed through this authorization.

Upon selecting "Agree" you will be taken to the Authorization Form to complete the sign-up process.

We’re sorry, you must agree to the Terms of Use in order to connect with a mentor.