Forensic Psychiatry, Pharmacogenetics & Adverse Drug Reactions

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Curriculum Vitae, Dr Yolande Lucire,PhD MBBS DPM

Download CVQualifications2012 SafeSciMET Certificate : Stratification: Pharmacogenetics and Drug Safety, Karolinska Institutet1996 PhD UNSW in Arts and Social Sciences in History and Philosophy of Science1970 Member, then Fellow, Royal Australian & New Zealand College of Psychiatry (RANZCP)1967 Diploma of Psychological Medicine, London 1964 MB BS, University of Sydney

Work2009 - Current Medico-legal psychiatry and medico-legal issues in psychiatry related to workers’ compensation claims, and research and publishing on genetic links to adverse drug reactions to psychiatric drugs.1972 - 2008 Private practice, originally child and family, then general, forensic and medico-legal psychiatry in Sydney; medico-legal work relating to psychiatric defences in criminal proceedings and workers’ compensation/ personal injury claims, and research and publishing. 2001 - 2006 Conjoint Senior Lecturer, Psychiatry, Rural Medical School.1997 - 2005 Consultant Psychiatrist, Nolan House, Albury.1994 - 1995 Consultant Forensic Psychiatrist, London, Devonshire Place, Locum Consultant Psychiatrist, East Ham Memorial Hospital.Fellow Wellcome Institute for the History of Medicine. (Completing PhD).1983 -1995 Senior Forensic Psychiatrist, Consultant to Department of Corrective Services NSW, and Long Bay Prison Hospital. 1972 - 1980 Consultant (VMO) South Sydney Hospital,(including Rehabilitation) Psychiatrist, Rozelle Hospital, Sydney.1972 - Present Consultant Psychiatrist in private practice, Sydney.1967 - 1972 General Practice. 1968 - 1970 Senior Registrar in Child Psychiatry, Royal Alexandria Hospital for Children.1967 Registrar, Sutton & Belmont Hospital, Surrey, UK. 1965 SRMO, Netherne Hospital, Surrey, UK.1964 RMO, Prince Henry Hospital.BookConstructing RSI: Belief and Desire, UNSW Press, 2003.Publications in peer reviewed medical and forensic journals 1)Factors Affecting Conception in Women Seeking Termination of Pregnancy. Medical Journal of Australia 1975 (pages 824-27).2)‘I Fear the Greeks.’ Legal Service Bulletin, Feb. 1981. A medico-political expose of Social Security Conspiracy (prepared originally for a conference of psychiatry and law but deemed sub-judice at the time). Submission to the Minister and Commission of Inquiry into Social Security Prosecutions. 3)The Medical Evidence in the First 50 Administrative Appeals Tribunal Decisions. Legal Service Bulletin, Dec. 1982. (Australian) Analysis of the difficulties of evaluation of Invalid Pension applicants. 4)Neurosis in the Workplace. 1986 Medical Journal of Australia 145: 323-7. This paper has been given many citations both in medical and in social science journals.5)PhD. Ideology and Aetiology: RSI: an epidemic of craft palsy.6)Medea - Anatomy of a Multicide.Journal of the Australian Academy of Forensic Sciences. December 1993. 7)Social Iatrogenesis of Epidemic Neurosis. (RSI) Journal of Community Health Studies XX (2) 1988. 8)Analysis of the Function of the Expert, in "The Expert Witness Self- Examined" in book, The Expert Medical Witness, Federation Press 1989.9)Sex and the practitioner: The Victim Presented at the Plenary Session of the Australian Academy of Forensic Sciences September 11, 2001. Australian Journal of Forensic Sciences. Vol. 34 no.1 18-22. 10)Comparison Codes Medical Practice Act and Common Law. Whither 200 years of due process? Australian Journal of Forensic Sciences. Vol 34, No.1, 22-24, 2002.11)The Bearing of Daubert on Sexual Abuse Allegations. Journal of the Australian Academy of Forensic Sciences. Vol 32, No. 245-59, 2001.12)By invitation: Editorial: From personalized medicine to personalized justice: the promises of translational pharmacogenomics in the justice system Wong SH, Happy C, Blinka D, Gock S, Jentzen JM, Donald Hon J, Coleman H, Jortani SA, Lucire Yolande, Morris-Kukoski CL, Neuman MG, Orsulak PJ, Sander T, Wagner MA, Wynn JR, Wu AH, Yeo KT.Pharmacogenomics. 2010, Jun;11(6):731-7.13)Lucire Y, Crotty C. Antidepressant-induced akathisia homicides associated with diminishing mutations in metabolizing genes of the CYP450 family. Pharmacogenomics and Personalized Medicine 2011:4 1–17.http://www.dovepress.com/articles.php?article_id=7993 Conference papers, Submissions, Other Publications 14)The Adversary System or a Better Way? Read at the RANZCP Conference 1983. Prepared as a submission on the Invalid Pension problem for Senator Grimes in 1982.15)When emotions get converted. On the genesis of RSI as Conversion Disorder Safety Australia, Feb. 1986. Read at Medical Mythology conference, November 1985.16)Institutionalised & Rewarded Neurosis: RSI, the Australian Disease. Australian Institute of Management Journal, April 1986.17)Differential Diagnosis of Conversion. Presented at RANZCP Annual Conference, May 1986.18)Resistance to Paradigm Shift, The Injury Theory versus the Psychosocial Model of Causation in Epidemic RSI. Read at RANZCP Annual Conference, May 1986. Analysis of sources of resistance to the psychosocial model.19)The Use of Proforma for Disability Evaluation. Paper presented RANZCP conference, Hobart, May 1985.20)The First Forensic Interview, "RSI" - the Use of a Pre-Printed Proforma. Presented November 1985 and available in video from the Institute of Psychiatry, Rozelle Hospital. Also available in print.21)Square Pegs in Round Holes: A Comparison of Medical & Legal Concepts of "Causation" in Epidemic Neurosis, using the epidemic of RSI Proceedings of Conference of the Medico-legal Society of Victoria. Kota Kinabalu, Malaysia,1986.22)Workers' Compensation: A New Approach:Submission to writers of white paper on workers' compensation in NSW, 1986.23)Theory and Philosophy of Assessment: An analysis of the sources of variance in expert opinion evidence. Forensic Psychiatry Bulletin, 1986.24)RSI, an Epidemic of Craft Palsy. A chapter commissioned by Dr. (now professor) Professor Ivor Jones, then Snr. lecturer in Psychiatry, Melbourne University, for text book, "Essentials of Australian Forensic Psychiatry," 1986. (This book was never published).25)The Role of the Psychiatric Assessor in Personal Injury Claims. Presented at RANZCP Forensic Psychiatry Conference Leura, November 1990.26)Repetitive Strain Injury - An Epidemic of Craft Palsy. Proceedings of the Medico-Legal Society of NSW. Vol. 8, pages 134-146.27)Chronic Fatigue Syndrome:What is a disease? Debate with the Prince of Wales Hospital, Presented in November 1990, at the Institute of Psychiatry in NSW, for Continuing Medical Education.28)The NSW Mental Health Review Tribunal, first seven years of operations. Presented RANZCP Forensic Section Conference November 15-20, 1991.29)Life events and getting sick with "RSI." Presented RANZCP Forensic Section Conference November 15-20, 1991.30)The Narcissist in the Culture of Compensation. Presented 1992 RANZCP Conference ,Brisbane.31)The five-colour theorem:A model to elucidate the components of illness, disease and morbidity. Presented at Philosophy and Psychiatry Conference, 1996.32)Can a Linear Medical Model Identify Causation of Illness? (Draft only). 33)How to do a Sex Abuse Evaluation. RANZCP Conference Forensic Section, June 2000, Port Douglas34)The Politicization of Medicine and the Medicalization of Industrial Relations. Presented at Garran and Baxter conference on Psychological Injury. 35)Comparative Analysis of Paradigmatic Assumptions of the True Believers and The Sceptics contributing to Moral Panic about Child Sexual Abuse. Published on website at www.lucire.com.au36)Health Status and Predicament in Claimants for RSI 1986-1992. RANZCP Forensic Section Conference, 2001.37)The Social Construction of the War Neuroses: Are We Being Served? Commissioned paper for 11th Brigade Senior Medical Officers Conference, 14 July, 2001, Townsville Presented again, RANZCP Forensic Section Conference, 2001. Published in BMJ online. http://www.bmj.com/cgi/eletters/322/7278/9538)Politicising Medicine and Medicalizing Industrial Relations (repeated) RANZCP Forensic Section Conference, 2001.39)Towards A Taxonomy of Confabulation RANZCP Conference Brisbane June 2001.40)Submission To: Proceedings Before Standing Committee on Law and Justice Inquiry Into Child Sexual Assault Matters. At Sydney on Friday 10 May, 2002.41)Confabulation: Forensic Issues. ANZAPPL Conference July 2002, Darwin.42)Submission to Ipp Inquiry: Review of the Law of Negligence: 43)SSRIs: Forensic Issues. Risk Benefit Analysis and Potential for Litigation In Australia.Duty To Warn? (PowerPoint)Presented at RANZCP Forensic Section Conference October 2003, Geelong. 44)The Use of Textual Analysis in Differentiating True from Fabricated Sex Abuse Allegations. (PowerPoint).Presented at RANZCP Forensic Section Conference October 2003, Geelong. 45)Submission to Productivity Commission on adverse responses to antidepressants and the increase in demand for mental health services. http://www.pc.gov.au/__data/assets/pdf_file/0003/17814/subpr047.pdf46)Pharma Fraud, Pharmacological Iatrogenesis and the Crisis In Mental Health. Precedent: (the Law Magazine) 2005.47)SSRIs: Do they cause suicide? The Science: Daubert Admissible Evidence. Australian Academy of Forensic Sciences, May 19, 2004. Also presented at International conference of Medical Law, Sydney, 2004.48)SSRIs and their effects on Mental Health Presentations: A plausible Hypothesis, (PowerPoint). Presented at RANZCP Forensic Section Conference October 2004, Fremantle.49)New Drugs New Problems: PowerPoint, presented Section of Forensic Psychiatry, April 9, 2005.50)New Drugs New Problems Medico-political Expose of the Suicide Crisis in Mental Health, Australian Journal of Forensic Sciences.51)The Ethics of the Solitary Empiricist: How Pharmas Changed Common Human Unhappiness into a Deficit Disease. Blackheath Philosophy Forum, May 9, 2005.52)Do Second Generation Antidepressants Cause Suicide? A Daubert Hearing. Health, Australian Journal of Forensic Sciences. May 19, 2004.53)Effects of Second Generation Antidepressants and Antipsychotics on Mental Health Services in Australia. Royal Australian and New Zealand College of Psychiatrists 40th Conference, Convention Centre, Sydney 22 to 27 May, 2005. 54)Akathisia and Crime: Product Liability Issues. Royal Australian and New Zealand College of Psychiatrists 40th conference, Convention Centre, Sydney 22 to 27 May, 2005.55)Submission to Commission of Inquiry: Acute Care Services in NSW Public Hospitals on the prevalence and costs of adverse drug reactions to the health service: focus on psychiatric drugs and Vioxx. 56)Re-focussing Upstream: New Psychiatric Drugs, Genetic Polymorphisms and Public Health. Prepared For Submission Special Commission of Inquiry: Acute Care Services in NSW Public Hospitals. (Garling Inquiry. This was ignored on the basis that "the health department does not agree with her.”)57)The Effects of Pharmaceutical Industry Fraud, and the Texas Medication Algorithm Project on Mental Health Costs And Demand, RANZCP Conference, Gold Coast, 2006.58)Submission To Commonwealth Minister of Health concerning the implementation of the Deloitte report commissioned by the Australian Centre for Health Research. Improving the Quality Use of Medicines in Australia; Realising the Potential of Pharmacogenomics, October 2008. http://www.tga.gov.au/alerts/medicines/pdseap-report2009.htm59)Genetic Polymorphisms, Antidepressants, Akathisia Homicide and the Crisis in Mental Health: Prototype for a Project to Provide Adequate Defences. Poster at The Bureau of Crime Statistics and Research’s 40th Anniversary Symposium, 18 – 19 February 2009.60)Submission to Complaints Handling Inquiry NSW Department of Health. http://www.scribd.com/doc/2220637/Review-Of-Inquiry-Into-Complaints-Handling-In-NSW-Health61)‘CYP450 Testing May Be Essential In Psychiatry.’ Presented at ASCEPT conference 2009. 62)Submission to Senate Suicide Inquiry 2010 on the Prevalence of Medication-Induced Suicide and its Relationship to Demand for Services, and Public Health. 63)Poster and presentation: Do Street Drugs Cause Schizophrenia and Does Pharmacogenetics Explain This Problem?Human Genome Meeting 2012, Darling Harbour, Sydney.64) Pharmacogenomics and Psychiatry Conference, New York, March 2012, presented Akathisia Homicides paper.65)The Australia and New Zealand Association of Psychiatry, Psychology and Law Conference, ‘Evolving Paradigms in Forensic Practice,’ Melbourne, November 2012, presented paper: Failure of regulators.66)Relevant information Report of the Psychiatric Drug Safety Expert Advisory Panel, 24 December 2009. This investigation was conducted on 90 of Dr. Lucire's 90 reported cases of akathisia in 2007.http://www.tga.gov.au/pdf/alerts-medicine-ssri-pdseap-091224.pdfThis report identified the problems with SSRI prescribing that I had been reporting.67)Annual Conference of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) in December 2012.Presented paper, “Do street drugs cause schizophrenia?Does pharmacogenetics explain this problem?”

Membership & Associations

Committee member: Australian New Zealand Association of Psychology, Psychiatry and the Law, NSW Branch. 2001-2005.

Council member: Australian Academy of Forensic Sciences, 2001- 2009.

Fellow: The Royal Australian and New Zealand College of Psychiatrists, Member Forensic Section (RANZCP)

(Now resigned).

Member: International Centre for the Study of Psychiatry and Psychology (ICSPP).

Invited Speaker: Conference of the Medico-legal Society of Victoria,Kota Kinabalu, Malaysia, 1986. Lecture: 'Square Pegs in Round Holes: A Comparison of Medical & Legal Concepts of "Causation" in Epidemic Neurosis, using the Epidemic of RSI as an example, Published in Proceedings'.