Probably possible. But I don't think this really fits for several reasons.
- The story is told from Guybrush's point of view, which makes a closeup rather out of place here.
- The style doesn't really fit. Other closeups are more photo realistic, while this one is an obvious drawing.
- The colors don't match. The entire face is off and that bright coat looks more like Bob's then LeChuck's.

Quote:

Originally Posted by Aububuh

I also forgot to mention that I've run the setup 3 times now, and it always produces the same results.

What version of MI1SE do you have?
What happens, if you run extract_classic.exe inside the tools folder?