Yi Chen

Simultaneous BOLD fMRI and fiber-optic recording of fluorescent calcium signal can help clarify the cellular contributions to neurovascular coupling in different brain regions of healthy and diseased animal models. A key challenge is to target the deep brain nuclei with only several hundreds of microns. The goal of this project is to create a robotic controlling system to target small brain nuclei inside the MRI scanner and automate the process to a large degree.