With support from the Esophageal Cancer Awareness Association, other organizations, and individuals, the NCCN Guidelines for Patients®: Esophageal Cancer has been updated from Version 2013 to Version 2015 to reflect the updates in the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for Esophageal Cancer. The 2015 Version addresses appropriate referral to cancer genetics professionals and new recommendations for surveillance have been added. Furthermore, information regarding the treatment of early cancers has been revised, and systemic therapy regimens have been updated. A digital version of the NCCN Guidelines for Patients®: Esophageal Cancer can be downloaded free-of-charge on NCCN.org/patients.