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CONCERTA® Basics

The Dose Makes the Difference

Once-daily CONCERTA® delivers all-day ADHD symptom control

Covers the all-important homework hours between 4 and 6 pm

CONCERTA® can help your child focus at home and at school

One morning dose of CONCERTA® provides all-day ADHD symptom control. CONCERTA® is the only ADHD treatment with the unique OROS® delivery system, which slowly releases
medication at an increasing rate throughout the day. One morning dose covers your child's busy day — including the all-important homework hours between the hours of 4 and 6 pm.

Methylphenidate, the medication in CONCERTA®, has been prescribed for over 50 years. CONCERTA® is recommended among first-line therapies by the American Academy of Pediatrics, as part of a total treatment program. This includes both medication and behavioral therapy.

CONCERTA® is proven to help manage the symptoms of inattention, hyperactivity, and impulsivity. With these symptoms under control, your child can focus better and pay closer attention to the things he or she is doing throughout the day. All of this may help your child manage ADHD
symptoms at school, at home, and at play.

At school, teachers reported that children taking CONCERTA® showed improvements in ADHD symptoms as measured in areas such as focusing better, paying better attention, and completing projects they started. In a laboratory school study, improved attention in children was
demonstrated by completing more math problems accurately throughout the day.

CONCERTA® is approved for doses up to 54 mg per day in children and 72 mg per day in adolescents. Children are typically started on a daily dose of 18 mg of CONCERTA®. But, like many ADHD medications, your child's dosage may need to be adjusted to achieve better results. This approach is called titration. Your child's healthcare professional can determine which dose is
right for your child.

Over 53 million prescriptions have been written for CONCERTA®. With more than 9 years of proven safety, CONCERTA® has been studied in clinical trials in over 2,700 children and adolescents. And CONCERTA® is medication for children and adolescents with ADHD.

Help your child get on the path to success in managing ADHD symptoms. If your child has been
diagnosed with ADHD, ask about managing everyday challenges with CONCERTA®.

CONCERTA® is a prescription product approved for the treatment of attention deficit hyperactivity disorder (ADHD) as part of a total treatment program that may include counseling or other therapies.

IMPORTANT SAFETY INFORMATION
Talk to your healthcare professional for a proper diagnosis and treatment of ADHD. Only a healthcare professional can decide whether medication is right for you or your child.

Abuse of methylphenidate may lead to dependence. Tell your healthcare professional if you or your child has had problems with alcohol or drugs. Keep CONCERTA® in a safe place to prevent misuse and abuse.

CONCERTA® should not be taken by patients who have: allergies to methylphenidate or other ingredients in CONCERTA®; significant anxiety, tension, or agitation; glaucoma; tics, Tourette's syndrome, or family history of Tourette's syndrome; current or past use of monoamine oxidase inhibitor (MAOI); esophagus, stomach, or intestinal narrowing. Children under 6 years of age should not take CONCERTA®.

Tell your healthcare professional if you or your child has had any heart problems, heart defects, high blood pressure, or a family history of these problems; has had depression, abnormal thoughts or visions, bipolar disorder, or seizure. Tell your doctor if you have or your child has numbness, pain, skin color change or sensitivity to temperature in fingers or toes. Contact your healthcare professional immediately if you or your child: develops abnormal thinking or hallucinations, abnormal or extreme moods and/or excessive activity; or if aggressive behavior or hostility develops or worsens while taking CONCERTA®. Painful and prolonged erections (priapism) have occurred with methylphenidate. If you or your child develop priapism, seek medical help right away. Because of the potential for lasting damage, priapism should be evaluated by a doctor immediately. Your child's healthcare professional should check height and weight often and may interrupt CONCERTA® treatment if your child is not growing or gaining weight as expected.

Stimulants may impair the ability of the patient to operate potentially hazardous machinery or vehicles. Caution should be used accordingly until you are reasonably certain that CONCERTA® does not adversely affect your ability to engage in such activities.

The most common adverse reaction in double-blind clinical trials (>5%) reported in children and adolescents was upper abdominal pain. The most common adverse reactions in double-blind clinical trials (>5%) in adult patients were decreased appetite, headache, dry mouth, nausea, insomnia, anxiety, dizziness, weight decreased, irritability, and hyperhidrosis.