Depression

Models that used coded clinical data from electronic health records predicted antidepressant treatment response in general but not response to specific antidepressants in patients with major depressive disorder.

Depression is “vastly underdiagnosed” in people with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), states a literature review published online in the Harvard Review of Psychiatry.

The protein GPR56 may provide an easy-to-measure biomarker of a patient’s response to antidepressants as well as a novel drug target for the treatment of major depressive disorder, according to a published study.

Women who had depressive symptoms during their third trimester of pregnancy, or persistently before and after giving birth, were twice as likely to have babies with very low levels of immunoglobulin A.

A single dose of psilocybin combined with psychotherapy produced significant improvements in emotional and existential distress in patients with cancer that lasted more than 4 years, according to a published study.