Formerly Langgangan, Sta. Praxedes can claim an exclusive situation which no other town in Cagayan was ever in. In 1917, Langgangan was plucked from Mountain Province to become part of Cagayan but because of boundary dispute it was decided that it had to go to the more aggressive Ilocos Norte. Finally in 1922, by an executive order, it was decided that it really belonges to Cagayan.

It was inhabited by Itnegs and Apayaos only to be overwhelmed by Ilocano migrants who now make this 11,000 hectares town their home.

Fishing is the main livelihood of the people which includes area weed gathering that results to having the dried seaweed "gamet" for a delicacy. Natural resources like oil, gold and forest products are likewise abound.

202 kilometers away from Tuguegarao and much nearer to Ilocos Norte having for a neighbor the famous town of Pagudpod. It has 18 barangays and is presently a 6th class municipality.