This is a lecture/ discussion course covering the molecular basis of human physiological systems and related methodologies used in modern physiological and medical research. The course is subdivided into six parts including: 1) Nerve, Muscle and Bone Physiology, 2) Hormones, Signal Transduction, and Regulation of Gene Expression, 3) Sensory Physiology (hearing, taste, vision, smell, pain), 4)Pathophysiology of Metabolic Diseases, 5) Cellular and Physiological Homeostasis, and 6) Regenerative Medicine. Given the interdisciplinary nature of the course, no single textbook will be used. Rather, clinically relevant research papers, review articles or specific book chapters (assigned by each lecturer) will be available for downloading at the RWJMS AMP website or via the Rutgers RWJMS Library website.