Background: Obesity in pregnancy is increasing and is a risk factor for metabolic pathology such as preeclampsia. Leptin is an adipokine which has a direct relationship to obesity.

Aim: to measure leptin in lean, obese and diabetic pregnant women at three months intervals throughout their pregnancies.

Methods: Pregnant women were recruited in the 1st trimester of pregnancy, and three groups were formed: a) with pregestational Body Mass Index (BMI) less than 25 kg/m2, b) BMI higher than 25 kg/m2 and c) with Gestational Diabetes Mellitus (GDM). Serum levels of leptin were measured with radioimmunoassay (RIA) technique.

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Please refer to this study by its ClinicalTrials.gov identifier: NCT01649167

Sponsors and Collaborators

Materno-Perinatal Hospital of the State of Mexico

Universidad Autonoma del Estado de Mexico

Investigators

Principal Investigator:

Verónica Jackeline García Solorio, MSc

Autonomous University of the State of Mexico

Study Chair:

Hugo Mendieta Zerón, PhD

Autonomous University of the State of Mexico

More Information

No publications provided

Responsible Party:

Hugo Mendieta Zeron, Researcher of the Medical Research Center (CICMED), Materno-Perinatal Hospital of the State of Mexico