This Is MS Multiple Sclerosis Community: Knowledge & Support

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Effective combination of minocycline and interferon-beta in a model of
multiple sclerosis.

Giuliani F, Fu SA, Metz LM, Yong VW.

Department of Clinical Neurosciences, University of Calgary, Calgary,
Alberta, Canada.

The objective of the current study was to investigate whether minocycline
improves the effect of an existing multiple sclerosis (MS) medication,
interferon-beta, on experimental autoimmune encephalomyelitis (EAE) in mice. ...

The protein coat which surrounds and protects the chlamydial elementary body relies on disulphide bonds within and between macromolecules to maintain its conformity. Reduction of these bonds disrupts the ...

Does anyone have any one have any casual recommendations as to what ABX to take, how much to take, and the frequency? I noticed that the trials running now only involve mino, or doxy, but I noticed several of you all posting that you are taking both? or other combo's? Why, what is the mode of action? As long as you are receiving the MMP's, isn't that what matters? Paratek is developing a non-antibiotic tetracycline, ...

Its interesting, but it seems like something that would be easy to prove (or disprove).

Elaine DeLack has a different point of view. Based on her research (she cites the Journal of Neuroscience Research; Archives of Neurology; Pharmacology, - Biochemistry and Behavior, Journal of Laboratory and Clinical Medicine; Annals of Neurology; Journal of Neurochemistry) she writes: "I believe that MS is a result of ...

I have been taking Minocycline 50 mg every other day for 3 weeks. I am slowly increasing it as I go. Anyways, for the last week or so I have had something like bone pain in my arm and then again in my right leg.

It was a good thing I was sitting down because when this spongy bone pain struck my right arm, I would have fallen. It was quick though. The leg ...

Sleep disorders are common in MS, with a flattening of the normal circadian sleeping/waking rhythm, leading to wakefulness at night and somnolence during the day One cause of this may be decreased nocturnal biosynthesis of melatonin [Wu YH et al., Molecular changes underlying reduced pineal melatonin levels in Alzheimer disease: alterations in preclinical and clinical stages. J Clin Endocrinol Metab. ...

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