What is pemphigoid nodularis?

Pemphigoid nodularis is a rare nodular variant of bullous pemphigoid. There is limited literature on pemphigoid nodularis to date, with only case reports describing the condition. It was first described by Provost et al (1979) and Yung et al (1981) [1,2].

What is the differential diagnosis for pemphigoid nodularis?

Pemphigoid nodularis can appear similar to nodularprurigo and other forms of prurigo. However, nodularprurigo lacks blisters and has no serum or immunofluorescence evidence of IgG to bullous pemphigoid antigens. Histology can be used to differentiate between the two conditions.

What is the treatment for pemphigoid nodularis?

The treatment for pemphigoid nodularis can be challenging. Topical steroid therapy alone is inadequate.