Chemical identification

Names and identifiers:

Rd toxin

Vomitoxin

Deoxynivalenol

4-Deoxynivalenol

Dehydronivalenol

4-Desoxynivalenol

RTECS YD0167000

EU number:

610-668-0

Description:

Deoxynivalenol (DON , Vomitoxin) is a type B trichothecene. It occurs in grains such as wheat, barley, oats, rye, and maize, rice, sorghum. Deoxynivalenol (DON ) is produced by numerous strains of Fusarium and some other fungi. Deoxynivalenol (DON ) poisonings occur both in humans and farm animals. Deoxynivalenol (DON ) is highly toxic, producing a wide range of immunological disturbances and is particularly noted for inducing feed refusal and emesis in pigs, hence the alternative name vomitoxin Deoxynivalenol (DON ) usually co-occurs with other Fusarium toxins, such as Zearalenone, Nivalenol and its derivates, as well as the group of fumonisins.

Further Information

Deoxynivalenol (DON ) is soluble in common polar organic solvents as acetonitrile, methanol and ethyl acetate, slightly soluble in water.

Compound Classification:

trichothecene type B mycotoxin

Storage, handling:

Store in a freezer upon arrival, at -10°C to -25°C

Protect from moisture

Other vendors may recommend higher temperatures for storage.

Applications:

The main toxic effect of Deoxynivalenol (DON ) is inhibition of protein synthesis via binding to the ribosome.In agricultural R&D, DON is widely used to select crops strains with increased resistance against Fusarium.