GenAge entry for klf-1 (Caenorhabditis elegans)

Gene information (ID: 1970)

Potential relevance to longevity and/or ageing

Observations

Ectopic expression of klf-1 in worms, performed in a transgenic line carrying an intestine-specific construct and resulting in a modest level of overexpression, extends lifespan by approximately 15%. This effect is wwp-1 dependent.