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Thursday, January 15, 2009

I had a patient with severe opthalmopathy with Graves' disease who I was going to send to RAI. I was concerned about the historical risk of worsening eye disease with RAI. Here is a meta-analysis which summmarizes all the RCT trials. It appears there is increase in patients with preexisting eye disease. May be a good idea to pretreat with prednisone.