Senior Scientist I, DMPK | 41-RHC-RA-0419

Pharmacyclics is committed to the development and commercialization of novel therapies intended to improve the quality and duration of life and to resolve serious unmet medical needs for cancer patients. Pharmacyclics is a wholly-owned subsidiary of AbbVie (NYSE:ABBV), a global, research-based biopharmaceutical company. Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products and a pipeline containing multiple promising new molecules that are being studied in more than 200 clinical trials for over 20 different types of cancer.

More than 1,200 Pharmacyclics and AbbVie research scientists, clinicians, marketing, operations and corporate professionals work in the San Francisco Bay Area. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. Together, we are striving to outsmart cancer.

To learn more about us, please visit us at http://www.pharmacyclics.com/

General Position Summary/Purpose: Provide in vitro ADME support to Pharmacyclics drug discovery and development projects. Conceive and implement novel experimental approaches to answer in vitro ADME questions in support of drug discovery and development projects. Investigate, develop, validate or optimize existing and new methods for solving project related scientific issues. Work closely with bioanalytical and PK scientists, and report into drug metabolism function, integrating DM and PK data to support preclinical development of drug candidates and regulatory submissions. Contribute to project science in the area of DMPK, by developing productive collaborations and communications with other groups across scientific disciplines.

Key Accountabilities/Core Job Responsibilities:

Routinely demonstrate scientific initiative and creativity in research or development activities.

Highly autonomous and productive in performing laboratory research requiring only minimal direction from supervisor.

Demonstrates high proficiency across a wide range of in vitro ADME technologies and capable of initiating new areas of investigation that are scientifically meaningful and can be incorporated into a research or development program.

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All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability.

If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process, or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact us at HR@pcyc.com for assistance.