In Super Mario World 2: Yoshi's Island, Chain Chomps would usually wait on a faraway hill until Yoshi & Baby Mario passed, then fly up and come crashing down, creating a big gap in the path. In later levels, a giant Chain Chomp would chase after Yoshi, eating the soft land underneath Yoshi's feet. If Yoshi managed to outrun it, it would accidentally bite a hard block, stop just short of Yoshi, and fall down. A much smaller Chain Chomp resides chained to a block in Sluggy the Unshaven's Fort (World 5, Level 4). This particular chomp, when turned into a "?" cloud, would lead to a room with an information block that would tell you a secret code to let you play the Yoshi vs. Bandit mini-games. Also in the game was a round boulder called a Chomp Rock, which could roll over enemies and serve as a boost for Yoshi.

A few Chain Chomps appeared in Super Mario Sunshine as red hotpuppies who left behind a trail of lava in Pianta Village. Mario would have to put them out with FLUDD (his combination water squirter/jetpack), pull their tails, and launch them into a pond. In a later episode, Mario faced a much larger Chomp, cooled it down, and dragged it to a spa to give it a hot bath.