Note=Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer.

Sequence similarities

Belongs to the mesothelin family.

Post-translationalmodifications

Both MPF and the cleaved form of mesothelin are N-glycosylated.Proteolytically cleaved by a furin-like convertase to generate megakaryocyte-potentiating factor (MPF), and the cleaved form of mesothelin.